# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Helicase_C PF00271.26 EPX70414.1 - 4.4e-16 58.5 0.0 1.1e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPX70414.1 - 3.1e-11 43.0 0.0 1.1e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase adh_short PF00106.20 EPX70415.1 - 1.2e-32 113.1 0.1 1.5e-32 112.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPX70415.1 - 5.3e-27 95.1 0.0 6.6e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPX70415.1 - 1.5e-14 54.1 0.0 2.3e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EPX70415.1 - 0.004 16.8 0.9 0.0074 15.9 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EPX70415.1 - 0.0049 16.3 0.3 0.013 14.9 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EPX70415.1 - 0.017 14.2 0.1 0.038 13.1 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EPX70415.1 - 0.03 14.3 0.2 0.06 13.3 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding NdhL PF10716.4 EPX70416.1 - 2.3 8.0 6.9 7.7 6.3 2.1 2.4 2 1 0 2 2 2 0 NADH dehydrogenase transmembrane subunit SpoIISA_toxin PF14171.1 EPX70416.1 - 8.8 5.5 7.8 12 5.0 5.4 1.3 1 1 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system AP_endonuc_2 PF01261.19 EPX70418.1 - 3.2e-35 121.3 0.0 1.1e-34 119.6 0.0 1.7 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel DUF2313 PF10076.4 EPX70418.1 - 0.11 11.8 0.0 0.31 10.3 0.0 1.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2313) AP_endonuc_2_N PF07582.7 EPX70418.1 - 0.14 11.7 0.1 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus Con-6 PF10346.4 EPX70419.1 - 1.8e-29 100.8 9.8 3.1e-15 55.2 0.5 2.2 2 0 0 2 2 2 2 Conidiation protein 6 MEF2_binding PF09047.5 EPX70419.1 - 0.15 11.7 0.2 15 5.3 0.0 2.3 2 0 0 2 2 2 0 MEF2 binding ALMT PF11744.3 EPX70419.1 - 0.37 9.3 2.3 0.4 9.2 1.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Toxin_43 PF15604.1 EPX70419.1 - 1.1 9.3 7.4 4.9 7.1 2.4 2.1 1 1 1 2 2 2 0 Putative toxin 43 RELT PF12606.3 EPX70419.1 - 3.6 6.8 5.1 0.6 9.2 0.9 1.8 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Catalase PF00199.14 EPX70420.1 - 2.1e-184 612.6 0.8 2.7e-184 612.2 0.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EPX70420.1 - 1.5e-16 60.0 1.7 3.3e-16 58.8 0.1 2.4 2 0 0 2 2 2 1 Catalase-related immune-responsive COX14 PF14880.1 EPX70421.1 - 0.00026 20.5 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly FtsL PF04999.8 EPX70421.1 - 0.032 13.9 0.0 0.035 13.8 0.0 1.0 1 0 0 1 1 1 0 Cell division protein FtsL RNase_PH PF01138.16 EPX70422.1 - 6.4e-22 78.2 0.2 1.6e-21 77.0 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EPX70422.1 - 2.5e-10 40.1 0.0 5.1e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 KH_1 PF00013.24 EPX70423.1 - 2e-40 136.2 3.6 3.7e-16 58.5 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EPX70423.1 - 4.2e-30 102.8 9.8 6.5e-12 44.8 1.7 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EPX70423.1 - 1.3e-11 43.8 3.3 0.0026 17.2 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EPX70423.1 - 3.9e-07 29.5 1.1 0.1 12.2 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EPX70423.1 - 0.00012 21.7 1.4 0.13 12.0 0.1 3.1 3 0 0 3 3 3 2 NusA-like KH domain MFS_1 PF07690.11 EPX70424.1 - 2.4e-44 151.5 24.9 1.3e-43 149.1 17.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily PepSY_TM PF03929.11 EPX70424.1 - 0.43 11.0 0.1 0.43 11.0 0.1 5.2 6 0 0 6 6 6 0 PepSY-associated TM helix DUF1228 PF06779.9 EPX70424.1 - 1.9 8.5 7.4 1.2 9.2 1.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) Alpha-amylase PF00128.19 EPX70425.1 - 6.1e-56 190.1 3.8 1.4e-55 188.9 2.7 1.5 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EPX70425.1 - 1.8e-16 59.9 0.4 1.8e-16 59.9 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) DUF187 PF02638.10 EPX70425.1 - 0.0064 15.4 0.4 0.012 14.4 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase like GH101 Vma12 PF11712.3 EPX70426.1 - 1.6e-15 57.0 0.6 2.3e-15 56.5 0.4 1.4 1 1 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Catalase PF00199.14 EPX70427.1 - 1.6e-174 580.1 0.2 2.2e-174 579.6 0.1 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EPX70427.1 - 1.6e-15 56.7 0.1 4.6e-15 55.2 0.1 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive MFS_1 PF07690.11 EPX70428.1 - 4.3e-23 81.5 24.4 4.3e-23 81.5 16.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UPF0542 PF15086.1 EPX70428.1 - 0.091 12.4 0.1 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Pombe_5TM PF09437.5 EPX70429.1 - 0.0015 18.0 8.1 0.0046 16.4 5.3 2.1 1 1 0 1 1 1 1 Pombe specific 5TM protein Redoxin PF08534.5 EPX70430.1 - 5.9e-31 106.9 0.1 6.7e-31 106.8 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EPX70430.1 - 2.9e-10 39.8 0.0 3.6e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family SAP PF02037.22 EPX70431.1 - 0.0058 16.1 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 SAP domain OMPdecase PF00215.19 EPX70432.1 - 3.3e-78 262.1 0.0 3.8e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family RAMP4 PF06624.7 EPX70433.1 - 0.00051 19.5 0.4 0.00069 19.1 0.3 1.3 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF4366 PF14283.1 EPX70433.1 - 0.096 12.0 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Glycos_transf_1 PF00534.15 EPX70434.1 - 9e-19 67.5 0.0 1.3e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPX70434.1 - 6.8e-09 35.9 0.0 1.8e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EPX70434.1 - 0.00014 21.6 0.0 0.00033 20.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Ribosomal_L6 PF00347.18 EPX70435.1 - 8.6e-33 112.6 3.7 1.1e-17 64.2 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 HMA PF00403.21 EPX70435.1 - 0.13 12.4 0.4 20 5.4 0.1 2.3 2 0 0 2 2 2 0 Heavy-metal-associated domain Ribosomal_L29 PF00831.18 EPX70437.1 - 3.6e-20 71.3 3.1 3.6e-20 71.3 2.1 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein Annexin PF00191.15 EPX70437.1 - 0.022 14.6 0.1 0.042 13.7 0.1 1.5 1 0 0 1 1 1 0 Annexin Ribosomal_S9 PF00380.14 EPX70437.1 - 0.028 14.6 2.3 0.077 13.2 1.6 1.7 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Snapin_Pallidin PF14712.1 EPX70437.1 - 0.05 13.9 1.2 0.05 13.9 0.8 1.7 1 1 0 1 1 1 0 Snapin/Pallidin DUF1013 PF06242.6 EPX70437.1 - 0.088 12.8 3.8 0.13 12.2 1.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1013) GAS PF13851.1 EPX70437.1 - 0.13 11.4 10.7 0.051 12.7 2.2 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding SRP_SPB PF02978.14 EPX70437.1 - 0.15 12.3 1.2 2.3 8.5 0.1 2.1 1 1 1 2 2 2 0 Signal peptide binding domain Prefoldin PF02996.12 EPX70437.1 - 0.83 9.3 6.0 2.2 7.9 0.0 2.6 3 0 0 3 3 3 0 Prefoldin subunit PGC7_Stella PF15549.1 EPX70437.1 - 1.9 8.4 5.0 2.3 8.1 3.5 1.1 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain UNC45-central PF11701.3 EPX70438.1 - 3e-07 30.2 9.5 0.0001 21.9 0.3 3.7 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 EPX70438.1 - 0.0021 18.3 2.1 0.22 11.8 0.1 3.8 4 1 0 4 4 4 1 HEAT repeats V-ATPase_H_C PF11698.3 EPX70438.1 - 0.05 13.5 0.2 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 V-ATPase subunit H HEAT PF02985.17 EPX70438.1 - 0.059 13.4 0.6 18 5.7 0.0 3.7 2 0 0 2 2 2 0 HEAT repeat Arm PF00514.18 EPX70438.1 - 0.86 9.5 11.0 1.2 9.1 0.0 5.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat zf-HIT PF04438.11 EPX70439.1 - 3e-08 33.1 13.1 4.7e-08 32.5 9.1 1.3 1 0 0 1 1 1 1 HIT zinc finger BUD22 PF09073.5 EPX70439.1 - 2.1 7.3 17.0 0.21 10.6 8.8 1.5 2 0 0 2 2 2 0 BUD22 BCIP PF13862.1 EPX70440.1 - 3.5e-71 238.7 0.3 4.4e-71 238.4 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PepX_N PF09168.5 EPX70440.1 - 0.042 14.0 0.3 1.7 8.8 0.1 2.9 2 1 1 3 3 3 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Helicase_Sgs1 PF11408.3 EPX70440.1 - 0.49 10.2 2.2 1.3 8.8 0.0 2.6 3 0 0 3 3 3 0 Sgs1 RecQ helicase tRNA_int_end_N2 PF12928.2 EPX70441.1 - 2.7e-28 97.2 0.1 5e-28 96.3 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EPX70441.1 - 0.0097 15.4 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Peptidase_M16 PF00675.15 EPX70442.1 - 1.5e-20 73.4 0.0 3e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EPX70442.1 - 2.5e-14 53.3 0.0 1.4e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain WD40 PF00400.27 EPX70443.1 - 1.2e-16 59.8 13.5 3.5e-06 26.6 0.0 7.1 8 1 1 9 9 9 3 WD domain, G-beta repeat Lgl_C PF08596.5 EPX70443.1 - 0.012 14.0 0.3 0.052 11.9 0.0 2.2 3 0 0 3 3 3 0 Lethal giant larvae(Lgl) like, C-terminal DUF3548 PF12068.3 EPX70443.1 - 0.051 12.8 0.1 0.092 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) SNF2_N PF00176.18 EPX70444.1 - 1.6e-67 227.4 0.0 2.4e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPX70444.1 - 7.9e-12 44.8 0.0 2.1e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EPX70444.1 - 2.6e-07 30.2 7.5 2.6e-07 30.2 5.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPX70444.1 - 0.00011 22.1 7.3 0.00011 22.1 5.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPX70444.1 - 0.00011 21.9 6.8 0.00011 21.9 4.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DEAD PF00270.24 EPX70444.1 - 0.00041 19.8 0.1 0.0012 18.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 EPX70444.1 - 0.00086 19.0 7.2 0.00086 19.0 5.0 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPX70444.1 - 0.0028 17.2 6.0 0.0028 17.2 4.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPX70444.1 - 0.01 15.5 3.1 0.027 14.1 2.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EPX70444.1 - 0.22 11.3 3.6 0.56 10.0 2.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein LRR_6 PF13516.1 EPX70445.1 - 9.2e-05 22.1 19.5 18 5.8 0.2 9.4 9 1 1 10 10 10 1 Leucine Rich repeat zf-MIZ PF02891.15 EPX70445.1 - 0.0062 16.0 0.6 0.014 14.9 0.4 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger RFPL3_antisense PF10489.4 EPX70445.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Ret finger protein-like 3 antisense LRR_2 PF07723.8 EPX70445.1 - 0.044 14.2 0.8 0.044 14.2 0.6 3.7 4 0 0 4 4 4 0 Leucine Rich Repeat Ste50p-SAM PF09235.5 EPX70445.1 - 0.065 13.2 1.2 6.1 6.9 0.1 3.3 3 1 0 3 3 3 0 Ste50p, sterile alpha motif DUF1183 PF06682.7 EPX70446.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) HSP20 PF00011.16 EPX70447.1 - 6.4e-22 77.3 0.8 7.6e-22 77.0 0.5 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EPX70447.1 - 0.0083 16.6 0.5 0.15 12.6 0.1 2.1 2 0 0 2 2 2 1 CS domain PIH1 PF08190.7 EPX70447.1 - 0.012 15.1 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF4097 PF13349.1 EPX70447.1 - 0.018 14.5 0.1 0.041 13.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) OmpA PF00691.15 EPX70447.1 - 0.11 12.8 0.1 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 OmpA family GPI-anchored PF10342.4 EPX70448.1 - 3.4e-10 40.2 0.3 4.1e-10 40.0 0.2 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 EPX70449.1 - 1.7e-13 50.8 1.3 2.1e-13 50.5 0.9 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tubulin PF00091.20 EPX70450.1 - 1.1e-73 247.6 0.0 1.8e-73 246.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPX70450.1 - 9.5e-46 154.9 0.8 1.7e-45 154.1 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EPX70450.1 - 1.6e-06 28.1 0.0 3.9e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Transposase_mut PF00872.13 EPX70450.1 - 0.13 10.7 0.1 6.5 5.1 0.0 2.2 2 0 0 2 2 2 0 Transposase, Mutator family Isy1 PF06246.7 EPX70451.1 - 1.6e-53 181.7 8.8 5.9e-52 176.6 6.1 2.0 1 1 0 1 1 1 1 Isy1-like splicing family DUF1005 PF06219.7 EPX70451.1 - 0.033 12.8 0.0 0.046 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) YolD PF08863.5 EPX70451.1 - 0.077 12.8 1.7 0.48 10.2 0.1 2.3 2 0 0 2 2 2 0 YolD-like protein Cyclin_N PF00134.18 EPX70452.1 - 4.2e-16 58.6 0.2 8.7e-16 57.6 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPX70452.1 - 0.00018 21.4 0.1 0.01 15.7 0.0 2.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EPX70452.1 - 0.03 14.1 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat RINGv PF12906.2 EPX70453.1 - 2e-07 30.9 7.5 4.2e-07 29.9 5.2 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EPX70453.1 - 2.7e-05 23.8 6.0 2.7e-05 23.8 4.1 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING-like PF08746.6 EPX70453.1 - 0.011 15.7 4.6 0.011 15.7 3.2 1.8 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_2 PF13923.1 EPX70453.1 - 0.037 14.0 6.8 0.12 12.4 4.7 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EPX70453.1 - 0.056 13.0 9.6 0.14 11.8 5.9 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 EPX70453.1 - 0.28 10.8 6.6 0.69 9.6 4.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX70453.1 - 0.29 10.8 4.1 0.78 9.4 2.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EPX70453.1 - 6.1 6.8 8.8 3 7.8 3.9 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain DASH_Duo1 PF08651.5 EPX70454.1 - 8.4e-23 79.7 3.4 1.4e-22 79.0 2.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 SPOB_ab PF14682.1 EPX70454.1 - 0.081 12.7 1.6 0.14 11.9 1.1 1.4 1 1 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal DUF4435 PF14491.1 EPX70454.1 - 0.18 11.6 3.7 0.23 11.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) Bunya_G1 PF03557.10 EPX70454.1 - 0.29 8.8 3.2 0.36 8.5 2.2 1.0 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 hNIFK_binding PF12196.3 EPX70455.1 - 0.3 10.5 5.1 2.2 7.7 0.4 2.7 2 1 0 2 2 2 0 FHA Ki67 binding domain of hNIFK PGM_PMM_I PF02878.11 EPX70456.1 - 4.6e-36 123.3 0.1 8e-36 122.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EPX70456.1 - 3.1e-21 75.5 0.0 5.4e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EPX70456.1 - 3.2e-15 56.3 0.0 8.5e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EPX70456.1 - 4.6e-11 42.5 0.0 1.1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Cg6151-P PF10233.4 EPX70457.1 - 5.1e-35 119.8 15.2 6.2e-35 119.5 10.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cytochrom_B558a PF05038.8 EPX70457.1 - 0.32 10.5 11.4 2.4 7.7 7.9 2.2 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Bac_export_2 PF01312.14 EPX70457.1 - 0.61 8.9 7.1 0.67 8.7 5.0 1.0 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF373 PF04123.8 EPX70457.1 - 4.4 6.2 10.2 5.5 5.9 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Gp_dh_C PF02800.15 EPX70458.1 - 1e-73 245.9 0.0 1.7e-73 245.2 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EPX70458.1 - 6e-60 201.5 0.2 9e-60 201.0 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EPX70458.1 - 0.016 15.1 0.5 0.06 13.2 0.1 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EPX70458.1 - 0.12 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Tbf5 PF06331.7 EPX70459.1 - 4e-26 90.5 0.4 4.4e-26 90.4 0.3 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 zf-UBR PF02207.15 EPX70460.1 - 2.2e-18 65.7 12.3 2.2e-18 65.7 8.5 2.3 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EPX70460.1 - 0.00065 19.3 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Mago-bind PF09282.5 EPX70461.1 - 4.9e-10 38.7 0.1 1.1e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 Mago binding LCD1 PF09798.4 EPX70461.1 - 3.6 5.4 10.5 4.8 5.0 7.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein RNA_pol_Rbc25 PF08292.7 EPX70462.1 - 3.5e-39 133.7 0.0 5.1e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EPX70462.1 - 3.6e-17 62.2 0.0 5.2e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EPX70462.1 - 0.006 16.6 0.0 0.017 15.1 0.0 1.8 1 1 0 1 1 1 1 S1 RNA binding domain Pyr_redox_2 PF07992.9 EPX70463.1 - 7.2e-10 39.0 0.0 4.5e-09 36.4 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPX70463.1 - 0.004 16.1 0.0 0.95 8.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 EPX70463.1 - 0.0063 15.4 0.0 0.55 9.0 0.0 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EPX70463.1 - 0.069 12.9 0.0 14 5.4 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EPX70463.1 - 0.13 11.0 0.1 0.38 9.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 EPX70463.1 - 0.2 11.6 1.3 33 4.4 0.2 2.8 2 1 2 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase WTF PF03303.8 EPX70464.1 - 0.00072 19.0 6.0 0.0036 16.7 4.2 2.0 1 1 0 1 1 1 1 WTF protein DUF1404 PF07185.6 EPX70464.1 - 0.022 14.3 5.9 0.033 13.7 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1404) DUF1119 PF06550.6 EPX70464.1 - 0.72 8.9 9.5 0.99 8.4 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1119) Transketolase_N PF00456.16 EPX70465.1 - 1.1e-137 458.3 0.0 1.4e-137 457.9 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EPX70465.1 - 4e-45 153.4 0.0 8.1e-45 152.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EPX70465.1 - 2.4e-11 43.6 0.0 4.6e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 EPX70465.1 - 6.1e-09 35.0 0.0 1.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EPX70465.1 - 7.8e-06 25.5 0.1 5.9e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EPX70465.1 - 0.0002 20.4 0.0 0.00061 18.8 0.0 1.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase COPIIcoated_ERV PF07970.7 EPX70466.1 - 2.2e-33 115.7 0.0 3.2e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EPX70466.1 - 3.2e-20 71.8 0.0 1.2e-19 70.0 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ATP_bind_3 PF01171.15 EPX70467.1 - 2.1e-19 69.7 0.0 3.2e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EPX70467.1 - 0.00088 19.5 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 EPX70467.1 - 0.0035 15.9 0.0 0.0049 15.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.10 EPX70467.1 - 0.011 15.2 1.0 0.011 15.2 0.7 3.0 4 0 0 4 4 4 0 RecR protein Asn_synthase PF00733.16 EPX70467.1 - 0.088 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase DUF3970 PF13113.1 EPX70467.1 - 0.093 12.4 0.6 0.2 11.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) CK_II_beta PF01214.13 EPX70468.1 - 1.4e-71 239.8 0.0 1.7e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF2985 PF11204.3 EPX70468.1 - 0.07 12.8 0.0 0.59 9.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2985) DUF1682 PF07946.9 EPX70469.1 - 1.6e-70 237.5 0.4 1.9e-70 237.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Cyt-b5 PF00173.23 EPX70470.1 - 6.9e-24 83.4 0.1 8.8e-24 83.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LAMTOR PF15454.1 EPX70471.1 - 0.00076 19.7 0.5 0.0014 18.8 0.1 1.6 1 1 1 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF4266 PF14086.1 EPX70471.1 - 0.46 11.0 2.1 41 4.7 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4266) AAA PF00004.24 EPX70472.1 - 9.1e-16 58.2 0.0 2.2e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.13 EPX70472.1 - 1.5e-09 37.6 0.1 5.4e-09 35.8 0.1 2.0 2 0 0 2 2 2 1 BAH domain AAA_22 PF13401.1 EPX70472.1 - 2.4e-07 30.9 0.0 6.6e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPX70472.1 - 3.1e-07 30.5 0.0 1.4e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EPX70472.1 - 0.00031 20.4 0.0 0.00062 19.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EPX70472.1 - 0.002 17.8 0.0 0.017 14.8 0.0 2.5 1 1 0 1 1 1 1 Archaeal ATPase Zot PF05707.7 EPX70472.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_19 PF13245.1 EPX70472.1 - 0.013 15.2 0.0 0.034 13.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 EPX70472.1 - 0.015 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EPX70472.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 EPX70472.1 - 0.093 12.0 0.4 0.48 9.6 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Rad21_Rec8_N PF04825.8 EPX70473.1 - 4.5e-28 97.4 0.1 8.3e-28 96.5 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EPX70473.1 - 1e-12 47.0 2.1 1.2e-12 46.7 0.0 2.2 3 0 0 3 3 3 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EPX70473.1 - 2.4e-05 24.0 0.9 0.00016 21.3 0.0 2.3 2 0 0 2 2 2 1 ScpA/B protein Mt_ATP-synt_D PF05873.7 EPX70474.1 - 2.6e-10 40.1 0.5 3.6e-10 39.7 0.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Myosin_tail_1 PF01576.14 EPX70474.1 - 0.002 15.9 0.9 0.0027 15.5 0.7 1.3 1 0 0 1 1 1 1 Myosin tail DUF2681 PF10883.3 EPX70474.1 - 0.0082 16.3 1.5 0.066 13.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) XhlA PF10779.4 EPX70474.1 - 0.014 15.3 0.6 0.014 15.3 0.4 2.0 2 1 0 2 2 2 0 Haemolysin XhlA THDPS_N PF14790.1 EPX70474.1 - 0.015 14.8 0.6 0.12 11.9 0.4 2.0 1 1 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal AAA_13 PF13166.1 EPX70474.1 - 0.02 13.4 2.8 0.023 13.1 1.9 1.0 1 0 0 1 1 1 0 AAA domain COG2 PF06148.6 EPX70474.1 - 0.02 14.7 1.1 0.045 13.6 0.8 1.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 EPX70474.1 - 0.021 14.6 2.3 0.21 11.4 0.2 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EPX70474.1 - 0.027 14.7 6.4 0.54 10.5 2.5 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 EPX70474.1 - 0.027 14.3 0.3 0.035 13.9 0.2 1.2 1 0 0 1 1 1 0 Tropomyosin like Phage_GP20 PF06810.6 EPX70474.1 - 0.031 13.7 2.6 2.2 7.7 0.4 2.4 2 1 0 2 2 2 0 Phage minor structural protein GP20 TBPIP PF07106.8 EPX70474.1 - 0.035 13.6 3.7 0.1 12.1 2.5 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WEMBL PF05701.6 EPX70474.1 - 0.035 12.5 6.0 0.082 11.3 4.2 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF128 PF01995.11 EPX70474.1 - 0.036 12.9 0.2 0.14 11.0 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF128 FH2 PF02181.18 EPX70474.1 - 0.043 12.7 1.2 0.056 12.3 0.8 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain DapH_N PF08503.5 EPX70474.1 - 0.045 13.8 1.8 0.074 13.1 1.3 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal Spc7 PF08317.6 EPX70474.1 - 0.05 12.2 2.9 0.063 11.9 2.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ApoLp-III PF07464.6 EPX70474.1 - 0.071 13.1 5.7 1.2 9.1 0.8 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Vps51 PF08700.6 EPX70474.1 - 0.1 12.4 4.9 4.2 7.2 0.0 3.0 2 1 1 3 3 3 0 Vps51/Vps67 DUF1380 PF07128.7 EPX70474.1 - 0.11 12.2 0.3 0.28 11.0 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1380) DUF2408 PF10303.4 EPX70474.1 - 0.11 12.5 1.7 0.77 9.8 1.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) BLOC1_2 PF10046.4 EPX70474.1 - 0.11 12.5 5.2 7 6.8 0.6 2.5 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 EPX70474.1 - 0.12 11.5 1.8 0.16 11.1 1.3 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4201 PF13870.1 EPX70474.1 - 0.19 11.1 1.3 0.31 10.4 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) MCPsignal PF00015.16 EPX70474.1 - 0.24 10.9 4.9 0.35 10.3 3.0 1.4 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 EPX70474.1 - 0.25 11.1 4.0 6.1 6.6 0.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 EPX70474.1 - 0.4 10.5 3.0 0.63 9.9 0.7 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 EPX70474.1 - 0.49 10.1 3.2 1 9.1 0.4 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.6 EPX70474.1 - 5.7 6.9 8.7 7.3 6.5 1.8 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF1014 PF06244.7 EPX70475.1 - 6.9e-27 94.0 17.8 2e-26 92.5 12.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) U79_P34 PF03064.11 EPX70475.1 - 3.2 7.1 13.6 4.4 6.7 9.4 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 VPS9 PF02204.13 EPX70476.1 - 8e-23 80.4 0.2 2e-22 79.1 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Glyco_transf_8C PF08437.5 EPX70476.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal SEN1_N PF12726.2 EPX70477.1 - 1.6e-92 310.8 24.1 8.4e-47 159.6 4.9 2.6 1 1 1 2 2 2 2 SEN1 N terminal AAA_11 PF13086.1 EPX70477.1 - 3.2e-69 233.0 2.2 3.2e-69 233.0 1.5 2.9 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EPX70477.1 - 3.9e-62 209.2 0.0 1.1e-61 207.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPX70477.1 - 7.9e-12 44.7 0.0 2.1e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPX70477.1 - 9.1e-07 28.6 1.5 8.5e-05 22.2 0.1 3.2 2 1 1 3 3 3 1 AAA domain UvrD_C_2 PF13538.1 EPX70477.1 - 0.0043 17.1 0.0 0.016 15.3 0.0 2.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 EPX70477.1 - 0.01 15.2 0.1 0.028 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Glyco_hydro_72 PF03198.9 EPX70478.1 - 2e-126 421.2 7.9 2.5e-126 420.9 5.5 1.0 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EPX70478.1 - 3.1e-15 56.4 2.3 9.8e-15 54.8 1.6 1.9 1 0 0 1 1 1 1 X8 domain CAF1 PF04857.15 EPX70479.1 - 1.8e-55 188.1 2.8 2.1e-55 187.8 1.9 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 EPX70479.1 - 0.0041 16.6 0.3 3.1 7.2 0.0 2.8 3 0 0 3 3 3 2 3'-5' exonuclease SWM_repeat PF13753.1 EPX70480.1 - 0.035 13.1 0.1 3 6.8 0.0 2.7 2 0 0 2 2 2 0 Putative flagellar system-associated repeat ELYS PF13934.1 EPX70481.1 - 6.9e-45 153.5 3.7 9.5e-45 153.0 2.6 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly XPG_N PF00752.12 EPX70482.1 - 8.2e-31 106.2 0.0 1.7e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EPX70482.1 - 4.7e-23 81.0 0.0 1.1e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EPX70482.1 - 0.049 13.1 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 XPG domain containing SMC_N PF02463.14 EPX70483.1 - 1.9e-65 220.1 0.0 2.9e-65 219.5 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPX70483.1 - 1.7e-29 102.2 0.4 8.2e-29 100.0 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EPX70483.1 - 6.3e-12 46.0 25.5 1.6e-07 31.5 4.7 4.4 2 2 1 3 3 3 2 AAA domain AAA_29 PF13555.1 EPX70483.1 - 6.5e-08 31.9 0.0 1.6e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EPX70483.1 - 0.0034 17.2 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit YqgF PF14639.1 EPX70483.1 - 0.014 14.9 0.2 0.014 14.9 0.2 2.8 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 FtsK_SpoIIIE PF01580.13 EPX70483.1 - 0.06 12.8 1.8 0.34 10.3 0.2 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Reo_sigmaC PF04582.7 EPX70483.1 - 0.14 11.2 24.7 0.56 9.3 0.3 5.5 4 2 1 6 6 6 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EPX70483.1 - 0.17 12.1 0.0 0.17 12.1 0.0 6.3 3 2 0 4 4 4 0 ABC transporter AAA_23 PF13476.1 EPX70483.1 - 0.31 11.3 114.9 0.11 12.7 36.3 6.6 3 2 0 4 4 4 0 AAA domain CAF1A PF12253.3 EPX70484.1 - 1.1e-20 73.5 8.2 1.1e-20 73.5 5.7 3.4 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EPX70484.1 - 3.3e-14 52.8 54.7 3.3e-14 52.8 37.9 2.0 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CUE PF02845.11 EPX70484.1 - 0.019 14.4 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 CUE domain RRM_1 PF00076.17 EPX70485.1 - 3.5e-20 71.3 0.0 4.6e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX70485.1 - 8.8e-15 54.4 0.0 1.2e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX70485.1 - 0.00011 21.9 0.2 0.19 11.5 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 EPX70486.1 - 4.5e-65 219.1 0.0 7.3e-65 218.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EPX70486.1 - 2.2e-29 102.2 0.4 5.9e-29 100.9 0.2 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EPX70486.1 - 1.1e-21 77.4 0.0 2.7e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Spc97_Spc98 PF04130.8 EPX70488.1 - 1.6e-123 412.8 15.2 2e-123 412.6 10.5 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Epimerase PF01370.16 EPX70489.1 - 1.6e-50 171.7 0.0 2e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EPX70489.1 - 1.2e-25 89.2 0.2 2.4e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EPX70489.1 - 4.2e-17 61.7 0.0 9.6e-17 60.5 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EPX70489.1 - 1.2e-13 50.5 0.0 1.5e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPX70489.1 - 2e-12 47.3 0.0 3.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EPX70489.1 - 1.3e-09 38.3 0.0 2.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPX70489.1 - 4.9e-09 35.4 0.0 1.5e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EPX70489.1 - 8.1e-09 34.7 0.0 1.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EPX70489.1 - 9.7e-09 35.1 0.0 2.6e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EPX70489.1 - 0.00024 20.4 0.0 0.00046 19.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EPX70489.1 - 0.003 16.9 0.2 0.0052 16.1 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.1 EPX70489.1 - 0.009 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 EPX70489.1 - 0.0096 14.9 0.1 0.013 14.4 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EPX70489.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DapB_N PF01113.15 EPX70489.1 - 0.022 14.6 0.1 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DAO PF01266.19 EPX70489.1 - 0.19 10.6 0.9 0.3 9.9 0.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ran_BP1 PF00638.13 EPX70490.1 - 1.2e-19 70.5 0.0 3.1e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EPX70490.1 - 0.048 13.3 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 WH1 domain GRIP PF01465.15 EPX70491.1 - 6.6e-12 44.7 0.7 1.7e-11 43.4 0.5 1.8 1 0 0 1 1 1 1 GRIP domain KaiC PF06745.8 EPX70491.1 - 0.02 14.0 1.8 0.04 13.0 1.3 1.6 1 0 0 1 1 1 0 KaiC TSC22 PF01166.13 EPX70491.1 - 0.036 14.0 19.7 0.39 10.7 0.2 4.4 4 0 0 4 4 4 0 TSC-22/dip/bun family TMCO5 PF14992.1 EPX70491.1 - 0.037 13.1 27.2 0.054 12.6 18.8 1.3 1 0 0 1 1 1 0 TMCO5 family Mitofilin PF09731.4 EPX70491.1 - 0.07 11.7 27.4 0.088 11.4 19.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GRAB PF10375.4 EPX70491.1 - 0.089 12.5 0.3 0.28 10.9 0.2 1.9 1 0 0 1 1 1 0 GRIP-related Arf-binding domain Macoilin PF09726.4 EPX70491.1 - 0.094 10.9 20.4 0.11 10.7 14.2 1.1 1 0 0 1 1 1 0 Transmembrane protein MAGE_N PF12440.3 EPX70491.1 - 0.11 12.7 6.3 0.28 11.5 0.2 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal THOC7 PF05615.8 EPX70491.1 - 0.4 10.9 23.1 29 4.9 15.8 2.4 1 1 0 1 1 1 0 Tho complex subunit 7 IncA PF04156.9 EPX70491.1 - 0.53 9.8 28.5 29 4.1 19.0 2.3 1 1 0 1 1 1 0 IncA protein Syntaxin-18_N PF10496.4 EPX70491.1 - 0.83 9.5 10.5 1 9.2 6.0 2.3 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus CCDC155 PF14662.1 EPX70491.1 - 1.2 8.6 30.8 0.031 13.8 14.8 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Reo_sigmaC PF04582.7 EPX70491.1 - 1.3 8.0 5.5 3.4 6.7 3.8 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EPX70491.1 - 2.5 7.8 13.2 10 5.9 1.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) SPX PF03105.14 EPX70491.1 - 5.8 6.6 23.6 7.7 6.2 16.4 1.2 1 0 0 1 1 1 0 SPX domain Pox_A_type_inc PF04508.7 EPX70491.1 - 6.3 6.8 14.4 6 6.9 0.3 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Bap31 PF05529.7 EPX70491.1 - 6.8 6.1 25.8 5.9 6.3 5.3 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like TMF_TATA_bd PF12325.3 EPX70491.1 - 8.7 6.1 30.4 2.7 7.7 9.8 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Ish1 PF10281.4 EPX70492.1 - 2.1e-37 126.8 14.8 8.7e-06 25.7 0.1 7.9 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EPX70492.1 - 0.00018 21.0 0.2 7.5 6.1 0.1 4.8 4 0 0 4 4 4 2 HeH/LEM domain Apolipoprotein PF01442.13 EPX70492.1 - 0.00027 20.5 1.9 0.51 9.8 0.3 3.4 3 1 0 3 3 3 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EPX70492.1 - 0.0032 17.8 17.8 1 9.7 2.5 4.3 3 1 1 4 4 4 3 Bacterial protein of unknown function (DUF883) Slx4 PF09494.5 EPX70492.1 - 0.025 14.2 0.1 41 4.0 0.0 4.2 4 0 0 4 4 4 0 Slx4 endonuclease YtxH PF12732.2 EPX70492.1 - 0.51 10.7 25.3 1.3 9.4 3.5 5.7 3 2 0 3 3 3 0 YtxH-like protein DUF1664 PF07889.7 EPX70492.1 - 0.76 9.5 7.8 6.3 6.6 0.3 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Actin PF00022.14 EPX70493.1 - 1.4e-65 221.3 0.0 8.2e-38 129.8 0.0 2.3 2 1 0 2 2 2 2 Actin DUF3793 PF12672.2 EPX70493.1 - 0.018 14.6 2.5 0.44 10.1 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) Kin17_mid PF10357.4 EPX70494.1 - 9.2e-50 167.5 3.5 9.2e-50 167.5 2.4 1.8 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EPX70494.1 - 0.00017 21.6 2.3 0.00045 20.3 1.6 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPX70494.1 - 0.00019 21.4 1.6 0.00051 20.0 1.1 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EPX70494.1 - 1.9 8.6 12.9 0.081 13.0 0.7 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DER1 PF04511.10 EPX70495.1 - 2.9e-34 118.3 9.4 3.5e-34 118.0 6.5 1.0 1 0 0 1 1 1 1 Der1-like family NMT_C PF02799.10 EPX70495.1 - 0.045 13.1 0.9 0.079 12.3 0.6 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DUF2818 PF10993.3 EPX70495.1 - 0.091 13.2 1.1 0.27 11.7 0.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2818) Rhomboid PF01694.17 EPX70495.1 - 0.13 12.3 9.4 0.15 12.0 5.8 1.7 2 1 0 2 2 2 0 Rhomboid family UPF0640 PF15114.1 EPX70495.1 - 0.52 9.8 2.8 1.1 8.7 0.1 2.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0640 DUF4118 PF13493.1 EPX70495.1 - 0.86 9.8 10.9 0.71 10.1 4.7 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4118) Rad60-SLD PF11976.3 EPX70496.1 - 3.2e-25 87.6 0.2 4.4e-25 87.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EPX70496.1 - 1.3e-10 40.5 0.1 1.8e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family TMF_TATA_bd PF12325.3 EPX70497.1 - 1.2e-26 92.8 48.1 2.3e-26 91.9 8.4 3.9 2 1 2 4 4 4 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EPX70497.1 - 2.4e-09 36.8 8.7 2.4e-09 36.8 6.0 6.3 4 2 2 6 6 6 2 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 EPX70497.1 - 0.0014 17.1 1.2 0.0014 17.1 0.8 2.8 2 1 1 3 3 3 1 AAA domain KLRAQ PF10205.4 EPX70497.1 - 0.0032 17.4 3.4 0.0032 17.4 2.4 5.4 2 2 3 5 5 5 1 Predicted coiled-coil domain-containing protein FliJ PF02050.11 EPX70497.1 - 0.016 15.2 2.0 0.016 15.2 1.4 5.4 2 2 2 5 5 5 0 Flagellar FliJ protein UPF0270 PF06794.7 EPX70497.1 - 0.22 11.3 5.1 5.1 6.9 0.5 3.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0270) DUF4407 PF14362.1 EPX70497.1 - 0.45 9.4 28.3 0.6 9.0 1.0 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) IncA PF04156.9 EPX70497.1 - 0.74 9.3 59.8 0.28 10.7 12.2 3.3 2 1 1 3 3 3 0 IncA protein TPR_MLP1_2 PF07926.7 EPX70497.1 - 1.3 8.7 55.8 1.8 8.3 9.2 5.2 3 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein FUSC PF04632.7 EPX70497.1 - 7 4.9 5.0 15 3.8 3.5 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Slu7 PF11708.3 EPX70498.1 - 4.2e-50 170.7 12.5 6.5e-50 170.1 8.7 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EPX70498.1 - 0.13 11.9 0.7 0.31 10.7 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3128 PF11326.3 EPX70498.1 - 1.1 9.3 5.3 0.51 10.5 1.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3128) RRM_6 PF14259.1 EPX70499.1 - 2.5e-16 59.3 0.0 5.2e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX70499.1 - 6.4e-14 51.3 0.0 1.6e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glycos_transf_1 PF00534.15 EPX70499.1 - 0.01 15.2 2.1 0.092 12.1 0.1 2.5 1 1 1 2 2 2 0 Glycosyl transferases group 1 Peptidase_C58 PF03543.9 EPX70499.1 - 5.1 6.5 10.8 2.1 7.7 0.7 2.7 1 1 1 2 2 2 0 Yersinia/Haemophilus virulence surface antigen PTPlike_phytase PF14566.1 EPX70499.1 - 6.3 6.8 7.9 0.84 9.6 2.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF1777 PF08648.7 EPX70499.1 - 9.1 5.9 21.8 4.4 7.0 8.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Ribosomal_L21e PF01157.13 EPX70500.1 - 2.9e-40 136.0 5.7 4.5e-40 135.4 4.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e UbiA PF01040.13 EPX70501.1 - 2e-30 105.9 20.8 2.7e-30 105.4 14.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family CRAL_TRIO PF00650.15 EPX70502.1 - 3e-23 82.0 0.0 4.4e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EPX70502.1 - 1.8e-07 31.1 0.0 3.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPX70502.1 - 2.4e-07 30.7 0.1 8.7e-07 28.9 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF1373 PF07117.6 EPX70502.1 - 0.062 13.0 0.1 0.12 12.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1373) Rota_NS35 PF02509.9 EPX70502.1 - 0.1 11.2 0.1 0.22 10.2 0.0 1.6 2 0 0 2 2 2 0 Rotavirus non-structural protein 35 Isochorismatase PF00857.15 EPX70503.1 - 5.5e-23 81.7 0.0 7e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family CbiG_N PF11760.3 EPX70503.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.6 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal Arrestin_C PF02752.17 EPX70504.1 - 7.4e-06 26.1 0.4 2.1e-05 24.6 0.1 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pkinase PF00069.20 EPX70505.1 - 4.1e-37 127.7 0.0 7.2e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70505.1 - 3.4e-29 101.7 0.0 5.1e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX70505.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EPX70505.1 - 0.014 15.1 0.0 0.67 9.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EPX70505.1 - 0.078 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RCC1 PF00415.13 EPX70506.1 - 3.6e-68 225.5 2.3 8.3e-14 51.5 0.0 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPX70506.1 - 8e-36 120.8 34.5 1e-07 31.4 0.5 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EPX70506.1 - 0.0017 17.8 2.3 16 5.1 0.0 4.8 5 0 0 5 5 5 1 Putative carbohydrate binding domain Kelch_2 PF07646.10 EPX70506.1 - 0.027 14.2 0.0 4.8 7.1 0.0 3.7 4 0 0 4 4 4 0 Kelch motif DUF2458 PF10454.4 EPX70507.1 - 1.1e-28 100.0 3.5 1.1e-28 100.0 2.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) DGCR6 PF07324.6 EPX70507.1 - 1.7e-05 24.4 1.4 3e-05 23.6 1.0 1.3 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein MipZ PF09140.6 EPX70507.1 - 0.065 12.3 0.3 0.12 11.4 0.2 1.4 1 0 0 1 1 1 0 ATPase MipZ EssA PF10661.4 EPX70507.1 - 0.16 11.6 4.4 0.15 11.7 1.6 2.0 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA RhoGAP PF00620.22 EPX70508.1 - 2.7e-36 124.4 0.0 4.2e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 EPX70508.1 - 0.069 11.9 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Sialidase_penC PF12135.3 EPX70508.1 - 0.16 11.6 0.7 0.32 10.6 0.2 1.7 2 0 0 2 2 2 0 Sialidase enzyme penultimate C terminal domain His_Phos_2 PF00328.17 EPX70509.1 - 4.9e-46 157.6 0.0 6e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Phage_holin_T PF11031.3 EPX70509.1 - 0.061 12.4 0.2 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage T holin Pkinase PF00069.20 EPX70510.1 - 5.4e-67 225.6 0.0 7.5e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70510.1 - 4.2e-45 153.8 0.0 6.4e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX70510.1 - 2.5e-05 23.4 0.0 4.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EPX70510.1 - 0.024 14.0 0.0 0.068 12.5 0.0 1.7 1 1 1 2 2 2 0 RIO1 family Endonuclease_5 PF04493.9 EPX70510.1 - 0.033 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Endonuclease V Seadorna_VP7 PF07387.6 EPX70510.1 - 0.09 11.5 0.0 0.73 8.6 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 Kdo PF06293.9 EPX70510.1 - 0.092 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RICTOR_N PF14664.1 EPX70512.1 - 3e-88 295.9 1.8 2.1e-87 293.1 0.5 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EPX70512.1 - 2.1e-87 291.8 5.1 6.5e-84 280.4 3.1 3.5 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EPX70512.1 - 5.4e-33 113.3 0.2 1.8e-31 108.4 0.0 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EPX70512.1 - 4.7e-27 93.7 0.1 9.6e-25 86.3 0.0 3.6 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.1 EPX70512.1 - 0.011 15.9 4.0 3.2 8.1 0.0 4.4 6 0 0 6 6 6 0 HEAT repeats KLRAQ PF10205.4 EPX70512.1 - 0.27 11.2 4.0 5.1 7.1 1.0 2.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein FAD_binding_1 PF00667.15 EPX70513.1 - 1.8e-60 204.1 0.0 2.6e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EPX70513.1 - 1.1e-12 48.5 0.0 6.3e-11 42.8 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain ox_reductase_C PF08635.5 EPX70514.1 - 1.3e-70 235.3 0.0 1.8e-70 234.8 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EPX70514.1 - 8.1e-18 65.0 0.0 1.4e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPX70514.1 - 0.0036 17.0 0.0 0.0081 15.9 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain FCH PF00611.18 EPX70515.1 - 2.6e-21 75.5 4.0 2.6e-21 75.5 2.8 3.2 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EPX70515.1 - 8.5e-21 73.2 0.1 2.3e-11 43.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EPX70515.1 - 8.8e-17 60.2 0.0 3.4e-09 35.9 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EPX70515.1 - 7.8e-16 57.3 0.0 2.6e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 EPX70515.1 - 3.3e-08 33.1 8.0 3.3e-08 33.1 5.5 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AIP3 PF03915.8 EPX70515.1 - 0.0037 16.2 9.4 0.0037 16.2 6.5 2.3 3 0 0 3 3 3 1 Actin interacting protein 3 Nbl1_Borealin_N PF10444.4 EPX70515.1 - 0.056 12.8 0.2 0.14 11.5 0.1 1.7 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal DEAD PF00270.24 EPX70516.1 - 1.3e-36 125.6 0.8 2e-36 125.0 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX70516.1 - 1.9e-23 82.0 0.1 3.7e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 EPX70516.1 - 0.033 13.7 0.2 0.11 12.1 0.1 1.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EPX70516.1 - 0.036 14.2 0.4 0.47 10.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.1 EPX70516.1 - 0.083 12.8 0.0 0.99 9.3 0.0 2.6 3 0 0 3 3 3 0 Helicase C-terminal domain Daxx PF03344.10 EPX70516.1 - 1.8 6.9 11.8 2.5 6.4 8.2 1.1 1 0 0 1 1 1 0 Daxx Family Spermine_synth PF01564.12 EPX70517.1 - 1.1e-98 329.0 0.0 1.3e-98 328.8 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EPX70517.1 - 3.5e-05 24.3 0.0 5.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX70517.1 - 0.00013 21.6 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX70517.1 - 0.0022 18.4 0.1 0.0055 17.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.11 EPX70517.1 - 0.02 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_24 PF13578.1 EPX70517.1 - 0.021 15.6 0.0 0.046 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EPX70517.1 - 0.051 12.9 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 EPX70517.1 - 0.084 12.0 0.4 0.78 8.8 0.1 2.4 2 1 1 3 3 3 0 O-methyltransferase 60KD_IMP PF02096.15 EPX70518.1 - 2.2e-44 151.4 3.8 3.2e-44 150.9 2.7 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein WD40 PF00400.27 EPX70519.1 - 2.3e-51 169.9 16.8 4.3e-11 42.2 0.1 11.2 11 0 0 11 11 11 8 WD domain, G-beta repeat PQQ_2 PF13360.1 EPX70519.1 - 2.2e-06 27.3 1.8 0.011 15.2 0.5 3.1 2 1 0 2 2 2 2 PQQ-like domain WAK PF08488.6 EPX70519.1 - 0.01 16.1 0.7 2.9 8.2 0.0 3.3 3 0 0 3 3 3 0 Wall-associated kinase IKI3 PF04762.7 EPX70519.1 - 0.022 12.6 0.5 3.2 5.4 0.0 2.7 2 1 1 3 3 3 0 IKI3 family PQQ_3 PF13570.1 EPX70519.1 - 0.035 14.3 5.1 10 6.5 0.0 5.6 4 2 1 5 5 5 0 PQQ-like domain PD40 PF07676.7 EPX70519.1 - 0.065 12.9 0.4 10 5.8 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat SH3_1 PF00018.23 EPX70520.1 - 1.6e-09 37.0 0.1 2.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPX70520.1 - 3.3e-08 32.9 0.1 5.9e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Transglut_core PF01841.14 EPX70520.1 - 1.7e-07 31.4 0.0 3.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_9 PF14604.1 EPX70520.1 - 2.2e-05 23.9 0.0 4.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4124 PF13511.1 EPX70521.1 - 2.3 8.3 5.1 2.7 8.1 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4124) Abhydrolase_2 PF02230.11 EPX70522.1 - 1.9e-40 138.6 0.0 2.1e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Pkinase PF00069.20 EPX70523.1 - 5e-66 222.5 0.0 8.7e-66 221.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70523.1 - 4.5e-49 166.8 0.0 7.1e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX70523.1 - 0.0028 16.6 0.0 0.031 13.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Lin-8 PF03353.10 EPX70523.1 - 0.061 12.5 0.5 0.094 11.9 0.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Exo_endo_phos PF03372.18 EPX70524.1 - 1.3e-27 97.3 0.1 2.3e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PQQ_3 PF13570.1 EPX70524.1 - 0.35 11.2 6.2 19 5.6 0.1 4.2 4 0 0 4 4 4 0 PQQ-like domain Septin PF00735.13 EPX70525.1 - 1.4e-106 355.6 0.2 2.3e-106 354.9 0.1 1.3 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EPX70525.1 - 3.5e-06 26.5 0.3 5.8e-05 22.6 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EPX70525.1 - 2.5e-05 23.5 0.0 6.9e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EPX70525.1 - 0.00012 21.9 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EPX70525.1 - 0.00028 21.0 0.1 0.002 18.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPX70525.1 - 0.011 16.0 1.2 0.064 13.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 EPX70525.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EPX70525.1 - 0.023 14.2 0.7 0.49 9.8 0.1 2.8 2 2 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EPX70525.1 - 0.027 14.6 0.2 0.18 11.9 0.0 2.4 2 1 1 3 3 3 0 RNA helicase AIG1 PF04548.11 EPX70525.1 - 0.034 13.2 1.5 0.05 12.6 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Gtr1_RagA PF04670.7 EPX70525.1 - 0.047 12.8 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 EPX70525.1 - 0.048 13.5 0.2 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EPX70525.1 - 0.058 13.8 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Sigma54_activat PF00158.21 EPX70525.1 - 0.074 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 EPX70525.1 - 0.14 11.6 0.7 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EPX70525.1 - 0.24 11.1 3.2 7.1 6.4 0.0 3.0 2 1 1 3 3 3 0 Dynamin family GCD14 PF08704.5 EPX70526.1 - 1.6e-99 332.3 0.0 2e-99 332.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EPX70526.1 - 0.00075 19.0 0.0 0.0017 17.9 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EPX70526.1 - 0.0015 19.0 0.0 0.024 15.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX70526.1 - 0.025 14.1 0.0 0.058 12.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MAGE_N PF12440.3 EPX70526.1 - 0.062 13.5 1.4 0.13 12.6 1.0 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Seryl_tRNA_N PF02403.17 EPX70526.1 - 0.2 11.7 2.0 0.39 10.7 1.4 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DMAP1 PF05499.7 EPX70527.1 - 2.1e-05 24.1 0.1 0.00049 19.7 0.0 2.2 2 0 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.26 EPX70527.1 - 0.0002 21.3 1.1 0.00041 20.3 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPX70527.1 - 0.00024 21.1 0.1 0.00093 19.2 0.1 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Dynamin_M PF01031.15 EPX70528.1 - 1.4e-107 358.9 0.3 1e-106 356.0 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EPX70528.1 - 1.2e-55 187.9 0.1 2.4e-55 186.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EPX70528.1 - 3.3e-26 91.0 5.4 7.5e-26 89.8 3.8 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EPX70528.1 - 0.00057 19.8 0.3 0.0052 16.7 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPX70528.1 - 0.031 14.7 0.0 0.1 13.0 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein Strep_SA_rep PF06696.6 EPX70528.1 - 9.7 6.0 6.5 1.5 8.6 1.8 1.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat PAP_assoc PF03828.14 EPX70529.1 - 4.1e-10 39.4 0.1 1.5e-09 37.6 0.1 2.1 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPX70529.1 - 2.4e-08 34.1 0.2 2.4e-07 30.9 0.0 2.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_central PF04928.12 EPX70529.1 - 1.4e-05 24.0 0.2 0.044 12.5 0.0 3.2 3 0 0 3 3 3 2 Poly(A) polymerase central domain HTH_36 PF13730.1 EPX70529.1 - 0.0094 16.0 0.7 0.14 12.2 0.1 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain tRNA_NucTransf2 PF09249.6 EPX70529.1 - 0.026 14.3 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain HTH_IclR PF09339.5 EPX70529.1 - 0.032 13.7 0.0 1.7 8.2 0.0 3.0 3 0 0 3 3 3 0 IclR helix-turn-helix domain MarR_2 PF12802.2 EPX70529.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 MarR family rRNA_proc-arch PF13234.1 EPX70530.1 - 4.3e-68 229.3 2.5 4.3e-68 229.3 1.7 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 EPX70530.1 - 4.3e-54 182.4 0.1 7.9e-54 181.6 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EPX70530.1 - 5.2e-23 81.3 0.1 1.2e-21 76.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX70530.1 - 5.4e-06 26.1 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 EPX70530.1 - 0.066 12.0 0.0 0.15 10.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-RanBP PF00641.13 EPX70532.1 - 4.2e-19 67.3 27.5 3.4e-09 35.6 0.7 4.3 4 0 0 4 4 4 3 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EPX70532.1 - 3.7e-07 29.6 0.0 7.5e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX70532.1 - 2.7e-05 24.0 0.0 5.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX70532.1 - 0.077 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ebp2 PF05890.7 EPX70533.1 - 6.2e-76 255.2 22.6 6.2e-76 255.2 15.7 2.2 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF4211 PF13926.1 EPX70534.1 - 3.2e-25 88.3 0.3 3.2e-25 88.3 0.2 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) SRP9-21 PF05486.7 EPX70535.1 - 4.7e-24 83.9 0.1 5.9e-24 83.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Mito_carr PF00153.22 EPX70536.1 - 1.1e-57 191.6 2.2 3e-21 74.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.17 EPX70537.1 - 7.2e-59 197.7 0.1 8.7e-59 197.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX70537.1 - 5.3e-21 75.3 0.0 8.4e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX70537.1 - 3.2e-09 36.2 0.0 3.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPX70537.1 - 1e-06 28.3 0.1 1.2e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPX70537.1 - 0.00014 21.7 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPX70537.1 - 0.012 14.8 0.2 0.017 14.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EPX70537.1 - 0.023 14.2 0.3 0.35 10.3 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 EPX70537.1 - 0.077 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Septin DUF2075 PF09848.4 EPX70537.1 - 0.079 11.9 0.0 0.14 11.0 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EPX70537.1 - 0.082 12.2 0.1 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPX70537.1 - 0.26 11.2 1.0 0.87 9.5 0.3 2.2 1 1 1 2 2 2 0 AAA ATPase domain CPSF_A PF03178.10 EPX70538.1 - 5.3e-61 206.4 3.6 1e-57 195.6 0.1 3.3 3 0 0 3 3 3 3 CPSF A subunit region MMS1_N PF10433.4 EPX70538.1 - 1.6e-45 155.1 4.7 3.1e-45 154.2 3.2 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF4597 PF15366.1 EPX70538.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Cofilin_ADF PF00241.15 EPX70539.1 - 1.1e-12 47.9 0.1 1.2e-12 47.7 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ribosomal_L50 PF10501.4 EPX70539.1 - 0.016 15.2 0.1 0.038 13.9 0.0 1.6 2 0 0 2 2 2 0 Ribosomal subunit 39S FAD_binding_6 PF00970.19 EPX70540.1 - 9.2e-14 51.3 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EPX70540.1 - 0.00016 22.1 0.0 0.001 19.6 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain AA_kinase PF00696.23 EPX70541.1 - 9.8e-39 133.3 0.4 1.5e-38 132.6 0.2 1.3 1 1 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EPX70541.1 - 2.3e-14 52.8 0.3 6.2e-14 51.4 0.1 1.9 2 0 0 2 2 2 1 PUA domain Thioredoxin PF00085.15 EPX70542.1 - 1.8e-57 191.4 0.0 3.9e-29 100.3 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EPX70542.1 - 5.3e-21 75.0 0.7 1.4e-20 73.7 0.5 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_8 PF13905.1 EPX70542.1 - 9.9e-13 48.0 1.3 5.9e-05 23.1 0.0 4.1 3 2 1 4 4 4 3 Thioredoxin-like Thioredoxin_2 PF13098.1 EPX70542.1 - 7.7e-12 45.4 5.6 0.00012 22.2 0.2 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EPX70542.1 - 4.4e-10 39.2 0.3 4e-05 23.2 0.1 2.8 2 1 1 3 3 3 2 AhpC/TSA family Thioredoxin_7 PF13899.1 EPX70542.1 - 4.6e-09 36.1 0.0 0.0026 17.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.1 EPX70542.1 - 2.1e-07 30.9 3.1 0.0013 18.5 0.1 3.5 2 1 1 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 EPX70542.1 - 7.3e-07 28.8 0.3 0.0024 17.4 0.1 2.5 2 1 0 2 2 2 2 Redoxin DnaI_N PF07319.6 EPX70542.1 - 0.0004 20.5 0.2 0.021 15.0 0.0 3.1 3 1 0 3 3 3 1 Primosomal protein DnaI N-terminus Thioredoxin_3 PF13192.1 EPX70542.1 - 0.00076 19.2 0.0 0.38 10.6 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_9 PF14595.1 EPX70542.1 - 0.00086 18.8 0.4 0.14 11.6 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin DDE_Tnp_1_2 PF13586.1 EPX70542.1 - 0.01 16.0 0.0 8 6.7 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain TraF PF13728.1 EPX70542.1 - 0.025 14.0 0.0 4.2 6.7 0.0 2.6 2 0 0 2 2 2 0 F plasmid transfer operon protein Activator-TraM PF11657.3 EPX70542.1 - 0.057 12.9 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM DSBA PF01323.15 EPX70542.1 - 0.076 12.5 0.3 5.2 6.5 0.0 3.1 2 1 1 3 3 3 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EPX70542.1 - 0.12 12.3 3.8 2.5 8.1 0.0 3.0 3 1 0 3 3 3 0 Thioredoxin Tom22 PF04281.8 EPX70543.1 - 6e-44 148.9 1.0 6.7e-44 148.7 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF3722 PF12519.3 EPX70544.1 - 4.5e-70 235.8 0.0 6.8e-70 235.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) WD40 PF00400.27 EPX70545.1 - 5e-27 92.7 24.2 1.2e-07 31.3 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EPX70545.1 - 1.2e-05 23.6 6.3 0.015 13.4 0.2 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Tox-GHH PF15636.1 EPX70545.1 - 0.085 12.5 0.0 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin STAG PF08514.6 EPX70546.1 - 9.3e-37 125.3 1.2 3.1e-36 123.6 0.8 1.9 1 0 0 1 1 1 1 STAG domain NOB1_Zn_bind PF08772.6 EPX70546.1 - 0.05 13.4 0.4 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Herpes_UL49_2 PF04823.7 EPX70547.1 - 0.1 12.6 0.6 0.24 11.3 0.4 1.6 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein CAP_GLY PF01302.20 EPX70548.1 - 5.7e-13 48.3 2.3 1.3e-12 47.2 0.8 2.0 2 0 0 2 2 2 1 CAP-Gly domain GAS PF13851.1 EPX70548.1 - 0.0004 19.6 9.4 0.0004 19.6 6.5 2.7 2 1 0 3 3 3 1 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 EPX70548.1 - 0.0038 16.2 18.6 0.0047 15.9 8.2 2.4 1 1 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 EPX70548.1 - 0.0076 15.9 0.5 0.0076 15.9 0.4 3.1 2 1 1 3 3 3 1 Mnd1 family CENP-F_leu_zip PF10473.4 EPX70548.1 - 0.012 15.4 24.5 0.22 11.3 8.8 3.4 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IL5 PF02025.10 EPX70548.1 - 0.044 13.8 0.4 0.11 12.4 0.3 1.6 1 0 0 1 1 1 0 Interleukin 5 AAA_27 PF13514.1 EPX70548.1 - 0.15 9.7 17.1 1.1 6.8 11.9 1.7 1 1 0 1 1 1 0 AAA domain NPV_P10 PF05531.7 EPX70548.1 - 0.29 11.3 3.7 8.2 6.7 2.0 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 EPX70548.1 - 0.4 10.2 18.5 2 7.9 0.8 2.7 2 2 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MCPsignal PF00015.16 EPX70548.1 - 0.44 10.0 6.1 0.14 11.6 1.9 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1492 PF07374.6 EPX70548.1 - 0.52 10.4 3.9 0.22 11.6 0.7 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1492) Tropomyosin_1 PF12718.2 EPX70548.1 - 0.69 9.7 25.6 0.7 9.7 8.5 2.8 3 1 0 3 3 3 0 Tropomyosin like DUF883 PF05957.8 EPX70548.1 - 0.74 10.2 7.5 0.28 11.5 2.9 2.0 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF883) DUF4250 PF14056.1 EPX70548.1 - 0.8 9.4 0.0 0.8 9.4 0.0 3.2 4 0 0 4 4 3 0 Domain of unknown function (DUF4250) Med10 PF09748.4 EPX70548.1 - 0.8 9.5 6.5 2.8 7.7 2.2 2.7 2 1 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex FUSC PF04632.7 EPX70548.1 - 0.88 7.9 6.9 0.85 7.9 4.1 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF3571 PF12095.3 EPX70548.1 - 0.89 9.8 7.1 21 5.4 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3571) Exonuc_VII_L PF02601.10 EPX70548.1 - 1.9 7.6 13.4 11 5.1 9.2 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit Phage_GP20 PF06810.6 EPX70548.1 - 3.3 7.1 12.0 0.23 10.8 3.2 2.6 2 2 1 3 3 3 0 Phage minor structural protein GP20 DUF2422 PF10337.4 EPX70548.1 - 4.7 5.8 6.6 1.4 7.6 2.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) Prefoldin_2 PF01920.15 EPX70548.1 - 4.8 6.9 24.6 0.4 10.4 0.2 4.8 3 1 0 3 3 2 0 Prefoldin subunit Spectrin PF00435.16 EPX70548.1 - 5.3 7.3 13.7 3.5 7.9 5.6 2.8 2 1 0 2 2 2 0 Spectrin repeat TPR_MLP1_2 PF07926.7 EPX70548.1 - 5.7 6.6 16.0 1.1 8.9 5.3 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Mod_r PF07200.8 EPX70548.1 - 5.9 6.7 18.4 0.3 10.9 6.4 2.7 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Histone_HNS PF00816.16 EPX70548.1 - 7.2 7.1 8.3 3.2 8.3 0.0 2.9 2 1 0 2 2 2 0 H-NS histone family BLOC1_2 PF10046.4 EPX70548.1 - 7.8 6.7 14.9 14 5.9 3.0 3.9 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Z1 PF10593.4 EPX70548.1 - 9.2 5.3 10.2 1.6 7.8 3.8 2.1 2 1 1 3 3 3 0 Z1 domain APG6 PF04111.7 EPX70548.1 - 9.6 5.1 20.1 2.4 7.1 7.3 2.4 2 0 0 2 2 2 0 Autophagy protein Apg6 G6PD_C PF02781.11 EPX70549.1 - 7.3e-78 261.3 0.2 1.3e-77 260.5 0.0 1.4 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EPX70549.1 - 4.9e-54 183.3 0.5 8.7e-54 182.5 0.3 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Flavodoxin_1 PF00258.20 EPX70550.1 - 1.2e-08 35.0 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EPX70550.1 - 2.6e-05 23.7 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase SNF2_N PF00176.18 EPX70551.1 - 6.6e-58 195.8 0.1 9.7e-58 195.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPX70551.1 - 6.8e-15 54.6 0.1 5.1e-13 48.6 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX70551.1 - 2.9e-06 27.2 0.5 1.7e-05 24.7 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Peptidase_U57 PF05582.7 EPX70552.1 - 0.3 9.9 6.6 3.5 6.5 4.6 2.0 1 1 0 1 1 1 0 YabG peptidase U57 F_actin_cap_B PF01115.12 EPX70553.1 - 1.1e-93 312.9 0.0 1.2e-93 312.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.12 EPX70553.1 - 0.0065 15.5 0.2 0.15 11.0 0.1 2.3 1 1 0 1 1 1 1 F-actin capping protein alpha subunit Bromodomain PF00439.20 EPX70554.1 - 2.8e-45 152.1 3.1 2.7e-23 81.6 0.2 2.8 3 0 0 3 3 3 2 Bromodomain Utp12 PF04003.7 EPX70555.1 - 1.1e-17 63.8 0.9 2.3e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 Dip2/Utp12 Family Aegerolysin PF06355.8 EPX70555.1 - 0.028 14.3 3.7 2.2 8.1 0.0 2.8 3 0 0 3 3 3 0 Aegerolysin TFIIA PF03153.8 EPX70555.1 - 1.2 8.9 23.0 3.4 7.4 16.0 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2407_C PF13373.1 EPX70556.1 - 1.3e-25 89.9 7.1 2.4e-24 85.8 4.9 2.3 1 1 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EPX70556.1 - 1.9e-16 60.0 0.0 4e-16 58.9 0.0 1.5 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EPX70556.1 - 0.11 12.1 0.0 0.62 9.7 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like ABC_tran PF00005.22 EPX70557.1 - 4.6e-58 195.3 1.1 7.1e-34 117.0 0.0 3.7 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EPX70557.1 - 4.7e-19 69.4 0.2 4.2e-08 33.4 0.1 4.2 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EPX70557.1 - 1.3e-13 50.6 0.0 0.00053 19.2 0.0 3.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EPX70557.1 - 9.3e-10 38.0 0.1 2.2e-09 36.8 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 EPX70557.1 - 7.5e-08 31.7 0.0 0.009 15.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EPX70557.1 - 8.8e-08 32.6 0.0 0.0086 16.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EPX70557.1 - 1.8e-07 31.1 0.1 0.098 12.6 0.0 3.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EPX70557.1 - 4.8e-07 30.6 0.0 0.059 14.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EPX70557.1 - 1.2e-06 28.2 0.0 0.14 11.8 0.0 3.6 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EPX70557.1 - 1.7e-06 27.7 0.1 0.15 11.4 0.0 3.9 4 0 0 4 4 4 1 AAA-like domain AAA_15 PF13175.1 EPX70557.1 - 1.8e-06 27.2 6.3 0.013 14.5 0.0 4.5 5 0 0 5 5 5 1 AAA ATPase domain DUF258 PF03193.11 EPX70557.1 - 7.1e-06 25.2 0.0 0.015 14.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPX70557.1 - 3.5e-05 23.9 0.0 0.15 12.2 0.0 3.5 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 EPX70557.1 - 4.2e-05 23.2 0.1 0.11 12.2 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA_25 PF13481.1 EPX70557.1 - 4.4e-05 22.9 0.0 0.15 11.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EPX70557.1 - 4.8e-05 23.3 0.0 0.51 10.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.12 EPX70557.1 - 0.00015 21.6 1.2 0.016 15.0 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 ArgK PF03308.11 EPX70557.1 - 0.00015 20.6 0.0 0.23 10.2 0.0 2.5 2 0 0 2 2 2 2 ArgK protein CLASP_N PF12348.3 EPX70557.1 - 0.00018 20.9 0.2 0.018 14.4 0.0 3.0 3 0 0 3 3 3 1 CLASP N terminal HEAT PF02985.17 EPX70557.1 - 0.00022 21.0 1.7 0.68 10.1 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat Dynamin_N PF00350.18 EPX70557.1 - 0.00027 20.7 0.0 0.75 9.5 0.0 3.3 2 1 0 2 2 2 1 Dynamin family AAA_16 PF13191.1 EPX70557.1 - 0.00032 20.7 4.5 0.5 10.3 0.2 3.5 3 2 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.17 EPX70557.1 - 0.00034 20.7 0.0 1.5 9.0 0.0 3.0 2 0 0 2 2 2 2 RNA helicase SbcCD_C PF13558.1 EPX70557.1 - 0.00043 20.1 0.1 0.53 10.2 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EPX70557.1 - 0.00044 20.6 14.5 0.037 14.3 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EPX70557.1 - 0.00048 20.3 0.1 0.92 9.7 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EPX70557.1 - 0.00056 19.6 1.2 0.43 10.2 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase AAA_33 PF13671.1 EPX70557.1 - 0.00076 19.3 0.1 1.7 8.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain HEAT_EZ PF13513.1 EPX70557.1 - 0.0013 19.1 2.0 15 6.1 0.0 5.2 4 0 0 4 4 4 0 HEAT-like repeat AAA_14 PF13173.1 EPX70557.1 - 0.0014 18.4 0.0 3 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.1 EPX70557.1 - 0.0016 18.7 6.4 0.011 16.0 0.0 4.3 3 2 1 4 4 4 1 HEAT repeats FtsK_SpoIIIE PF01580.13 EPX70557.1 - 0.0023 17.4 0.2 0.26 10.7 0.0 3.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_19 PF13245.1 EPX70557.1 - 0.004 16.8 0.1 0.78 9.5 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain DUF815 PF05673.8 EPX70557.1 - 0.0064 15.4 0.0 1.1 8.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EPX70557.1 - 0.011 15.2 0.1 0.36 10.3 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 EPX70557.1 - 0.021 14.3 0.0 3.8 6.9 0.0 2.8 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EPX70557.1 - 0.028 14.0 3.6 4.8 6.7 0.0 3.5 4 1 0 4 4 3 0 AAA domain GTP_EFTU PF00009.22 EPX70557.1 - 0.031 13.7 0.6 5.3 6.4 0.0 3.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EPX70557.1 - 0.035 13.6 0.0 12 5.3 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EPX70557.1 - 0.046 14.0 0.4 7.2 6.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 EPX70557.1 - 0.054 13.2 0.1 9.7 5.8 0.0 2.9 3 0 0 3 3 2 0 NTPase cobW PF02492.14 EPX70557.1 - 0.063 12.7 0.0 8.5 5.7 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EPX70557.1 - 0.067 12.7 0.0 9.8 5.6 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.1 EPX70557.1 - 0.074 11.5 3.1 7.6 4.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 EPX70557.1 - 0.12 11.9 0.4 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EPX70557.1 - 0.15 10.8 1.8 3 6.6 0.2 2.6 2 1 0 2 2 2 0 NB-ARC domain ABC_ATPase PF09818.4 EPX70557.1 - 0.28 9.6 1.9 9.8 4.6 0.0 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ATE_C PF04377.10 EPX70558.1 - 5.3e-46 155.8 2.1 5.3e-46 155.8 1.4 1.6 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EPX70558.1 - 4.6e-23 80.8 2.7 4.6e-23 80.8 1.9 2.1 2 1 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Pkinase PF00069.20 EPX70559.1 - 5.3e-61 206.0 0.0 1.2e-60 204.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70559.1 - 3.5e-31 108.2 0.0 6.3e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPX70559.1 - 0.097 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_76 PF03663.9 EPX70560.1 - 8.5e-44 150.4 10.5 1.1e-43 150.0 7.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.6 EPX70560.1 - 0.0068 15.4 0.2 0.29 10.1 0.1 2.4 2 0 0 2 2 2 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Fungal_trans PF04082.13 EPX70562.1 - 3.9e-31 107.8 0.2 1.3e-30 106.1 0.1 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX70562.1 - 2.8e-09 36.7 5.4 5.5e-09 35.7 3.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_25 PF13481.1 EPX70563.1 - 3.2e-06 26.6 0.0 8.2e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EPX70563.1 - 0.00037 19.6 0.1 0.05 12.7 0.0 2.2 2 0 0 2 2 2 2 KaiC Rad51 PF08423.6 EPX70563.1 - 0.00095 18.1 0.2 0.035 12.9 0.0 2.4 3 0 0 3 3 3 1 Rad51 RecA PF00154.16 EPX70563.1 - 0.0014 17.7 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_10 PF12846.2 EPX70563.1 - 0.0021 17.5 0.3 0.38 10.1 0.0 2.1 2 0 0 2 2 2 2 AAA-like domain IstB_IS21 PF01695.12 EPX70563.1 - 0.0037 16.7 0.0 0.0091 15.4 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein DnaB_C PF03796.10 EPX70563.1 - 0.095 11.5 2.3 1.4 7.7 0.4 2.8 2 1 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EPX70563.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain Pil1 PF13805.1 EPX70564.1 - 2.4e-101 338.4 0.1 3.2e-101 338.0 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Syja_N PF02383.13 EPX70565.1 - 4.3e-59 199.8 0.7 8.9e-58 195.5 1.7 1.8 1 1 1 2 2 2 1 SacI homology domain 6PF2K PF01591.13 EPX70566.1 - 7e-38 129.9 3.4 1.4e-37 128.9 2.4 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EPX70566.1 - 4.7e-27 95.0 0.0 9e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.5 EPX70566.1 - 2e-05 23.9 0.1 2.9e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EPX70566.1 - 0.00057 19.7 0.0 0.00099 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPX70566.1 - 0.0034 18.2 0.6 0.039 14.7 0.0 2.6 2 1 1 3 3 3 1 AAA domain DUF2048 PF09752.4 EPX70566.1 - 0.11 11.4 0.1 1.4 7.7 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2048) ATP-synt_C PF00137.16 EPX70567.1 - 1.6e-30 104.8 27.4 8.9e-18 63.9 4.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CLN3 PF02487.12 EPX70569.1 - 2e-77 260.6 29.9 2.5e-72 243.9 15.2 2.1 1 1 1 2 2 2 2 CLN3 protein DUF726 PF05277.7 EPX70570.1 - 7.5e-118 393.3 0.3 9.9e-118 392.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 EPX70570.1 - 0.0068 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 EPX70570.1 - 0.024 14.1 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.10 EPX70570.1 - 0.027 13.4 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2636 PF11120.3 EPX70571.1 - 0.12 11.9 0.6 0.18 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) PCI PF01399.22 EPX70572.1 - 7.7e-12 45.4 3.2 2.1e-11 44.0 0.1 2.9 3 1 0 3 3 3 1 PCI domain Metallopep PF12044.3 EPX70573.1 - 2.5e-140 467.6 0.0 2.9e-140 467.4 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EPX70573.1 - 0.0031 17.3 1.7 0.85 9.5 0.2 2.9 2 1 1 3 3 3 2 Jacalin-like lectin domain Reprolysin_2 PF13574.1 EPX70573.1 - 0.02 14.9 0.1 0.056 13.4 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EPX70573.1 - 0.021 14.7 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EPX70573.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Ribosomal_L7Ae PF01248.21 EPX70574.1 - 7.2e-26 89.5 0.0 8.8e-26 89.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EPX70574.1 - 0.0019 18.0 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 IPK PF03770.11 EPX70575.1 - 1.5e-41 142.2 0.0 1.9e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Calreticulin PF00262.13 EPX70576.1 - 4.1e-149 496.2 0.7 5.9e-149 495.6 0.5 1.2 1 0 0 1 1 1 1 Calreticulin family Peroxin-13_N PF04088.8 EPX70577.1 - 3.9e-24 85.3 2.2 5.8e-24 84.8 1.1 1.5 1 1 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EPX70577.1 - 1.7e-12 46.6 0.0 3.1e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EPX70577.1 - 9.8e-12 44.2 0.2 2.1e-11 43.1 0.1 1.6 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPX70577.1 - 1.1e-11 43.9 0.2 1.8e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SET PF00856.23 EPX70578.1 - 1.9e-09 38.0 0.0 1.5e-08 35.1 0.0 2.1 1 1 0 1 1 1 1 SET domain TFIIS_M PF07500.9 EPX70579.1 - 6.8e-29 100.2 4.9 8.4e-29 99.9 1.5 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EPX70579.1 - 1.6e-18 66.0 8.3 2.7e-18 65.3 5.7 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EPX70579.1 - 1.3e-11 43.7 0.2 2.9e-11 42.7 0.2 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Elf1 PF05129.8 EPX70579.1 - 0.053 13.2 2.6 0.096 12.3 1.8 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like ResIII PF04851.10 EPX70580.1 - 2.1e-23 83.1 0.1 6.9e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPX70580.1 - 7.4e-19 67.3 0.2 2.1e-18 65.9 0.1 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPX70580.1 - 1.5e-18 66.8 0.0 1.5e-16 60.3 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.1 EPX70580.1 - 0.012 15.7 0.0 0.069 13.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ARL2_Bind_BART PF11527.3 EPX70580.1 - 0.29 10.9 5.2 1 9.1 0.6 2.8 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART Aldolase_II PF00596.16 EPX70581.1 - 1.2e-38 132.5 0.0 1.4e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1604 PF07713.8 EPX70582.1 - 6.7e-32 109.1 2.2 6.7e-32 109.1 1.5 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch_2 PF12656.2 EPX70582.1 - 0.0057 16.4 0.0 0.024 14.4 0.0 2.2 1 1 0 1 1 1 1 DExH-box splicing factor binding site Allatostatin PF05953.7 EPX70582.1 - 0.13 12.7 0.3 0.48 11.0 0.2 2.0 1 0 0 1 1 1 0 Allatostatin Rad51 PF08423.6 EPX70583.1 - 9.5e-26 90.2 0.0 9.6e-25 86.9 0.0 2.2 1 1 0 1 1 1 1 Rad51 RecA PF00154.16 EPX70583.1 - 2.8e-08 33.2 0.0 9.6e-06 24.8 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_25 PF13481.1 EPX70583.1 - 4e-08 32.8 0.0 9.4e-08 31.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 EPX70583.1 - 2e-06 27.1 0.2 5.6e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.1 EPX70583.1 - 0.023 14.8 0.1 0.1 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPX70583.1 - 0.049 13.9 0.5 0.12 12.6 0.1 1.8 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 EPX70583.1 - 0.094 12.5 0.0 0.15 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.6 EPX70583.1 - 0.094 11.5 0.1 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 PAXNEB protein RNA_helicase PF00910.17 EPX70583.1 - 0.12 12.5 0.0 0.68 10.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase HA2 PF04408.18 EPX70585.1 - 1.7e-16 60.0 0.0 3.4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EPX70585.1 - 1.7e-13 50.4 0.0 3.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EPX70585.1 - 1.5e-11 43.9 0.0 3.8e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPX70585.1 - 5.4e-05 22.7 0.0 9.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPX70585.1 - 6.2e-05 23.1 0.1 0.00014 22.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPX70585.1 - 0.0014 18.5 0.4 0.06 13.2 0.3 2.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EPX70585.1 - 0.0047 15.8 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.22 EPX70585.1 - 0.026 14.8 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 EPX70585.1 - 0.2 11.8 1.5 1.4 9.0 1.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ufd2P_core PF10408.4 EPX70586.1 - 3.7e-181 603.5 23.1 4.7e-181 603.2 16.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EPX70586.1 - 3.5e-28 97.3 0.7 1.5e-27 95.3 0.3 2.3 2 0 0 2 2 2 1 U-box domain OGFr_N PF04664.8 EPX70586.1 - 0.0014 17.9 0.3 0.035 13.4 0.1 2.7 2 0 0 2 2 2 1 Opioid growth factor receptor (OGFr) conserved region Ras PF00071.17 EPX70587.1 - 6.6e-56 188.1 0.0 7.9e-56 187.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX70587.1 - 1.2e-15 57.9 0.0 1.8e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX70587.1 - 3.8e-05 23.0 0.0 5.2e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPX70587.1 - 0.033 13.4 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPX70587.1 - 0.038 13.1 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Sigma70_r2 PF04542.9 EPX70587.1 - 0.098 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 2 ICE2 PF08426.5 EPX70588.1 - 1.1e-99 333.8 34.5 1.3e-99 333.5 23.9 1.1 1 0 0 1 1 1 1 ICE2 Ribosom_S12_S23 PF00164.20 EPX70589.1 - 7.5e-40 135.1 0.5 8.9e-40 134.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mpp10 PF04006.7 EPX70590.1 - 2.2e-148 495.3 60.1 2.7e-148 495.0 41.7 1.0 1 0 0 1 1 1 1 Mpp10 protein PNK3P PF08645.6 EPX70591.1 - 7.6e-52 174.9 0.0 1.4e-51 174.0 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EPX70591.1 - 1.1e-25 90.2 0.1 4.4e-25 88.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPX70591.1 - 5.6e-08 32.1 0.0 0.0025 16.9 0.0 2.4 1 1 1 2 2 2 2 Zeta toxin KTI12 PF08433.5 EPX70591.1 - 6.3e-07 28.8 0.5 0.0017 17.6 0.1 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 HAD_2 PF13419.1 EPX70591.1 - 0.0013 18.9 0.1 0.22 11.7 0.0 2.9 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EPX70591.1 - 0.0015 18.4 0.0 0.0099 15.7 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase AAA_17 PF13207.1 EPX70591.1 - 0.0042 17.9 0.4 0.056 14.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain 6PF2K PF01591.13 EPX70591.1 - 0.0057 15.7 0.3 0.66 8.9 0.0 2.2 1 1 1 2 2 2 1 6-phosphofructo-2-kinase LNS2 PF08235.8 EPX70591.1 - 0.018 14.5 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) AAA_18 PF13238.1 EPX70591.1 - 0.019 15.3 0.0 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EPX70591.1 - 0.028 14.3 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EPX70591.1 - 0.066 13.3 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPX70591.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Pyrophosphatase PF00719.14 EPX70592.1 - 1.4e-50 170.8 0.1 1.8e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase TonB_2 PF13103.1 EPX70592.1 - 0.13 12.3 0.1 1.2 9.2 0.1 2.2 1 1 0 1 1 1 0 TonB C terminal DUF2417 PF10329.4 EPX70593.1 - 1.2e-53 181.9 5.5 1.6e-53 181.5 3.8 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EPX70593.1 - 7.9e-14 52.0 0.0 1.3e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPX70593.1 - 0.0023 17.6 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ail_Lom PF06316.6 EPX70593.1 - 0.065 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein Abhydrolase_1 PF00561.15 EPX70593.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold CBFD_NFYB_HMF PF00808.18 EPX70594.1 - 1.9e-28 98.2 0.5 2.7e-28 97.8 0.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPX70594.1 - 2e-08 34.2 0.0 3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EPX70594.1 - 0.0014 18.3 0.1 0.0018 18.0 0.0 1.3 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EPX70594.1 - 0.0029 17.2 0.1 0.0063 16.2 0.0 1.6 1 1 0 1 1 1 1 Bromodomain associated PAN_3 PF08277.7 EPX70594.1 - 0.016 14.7 0.2 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 PAN-like domain TFIID_20kDa PF03847.8 EPX70594.1 - 0.03 14.5 0.4 0.15 12.3 0.1 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A CENP-S PF15630.1 EPX70594.1 - 0.064 13.4 0.7 0.12 12.5 0.1 1.7 2 0 0 2 2 2 0 Kinetochore component CENP-S DUF1041 PF06292.12 EPX70594.1 - 0.51 10.5 2.7 2.1 8.5 1.8 1.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1041) tRNA-synt_2c PF01411.14 EPX70595.1 - 5.6e-220 731.3 0.1 9.1e-220 730.6 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EPX70595.1 - 2e-17 62.8 0.2 4.6e-17 61.6 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EPX70595.1 - 5.8e-08 32.3 0.1 1.6e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 DHHA1 domain Prok-TraM PF09228.5 EPX70595.1 - 0.019 15.0 0.9 0.16 12.1 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Dynactin_p22 PF07426.6 EPX70595.1 - 0.054 12.7 0.5 0.11 11.7 0.3 1.4 1 0 0 1 1 1 0 Dynactin subunit p22 HVSL PF09749.4 EPX70596.1 - 4.5e-44 150.2 3.4 5.3e-44 150.0 2.3 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Pkinase PF00069.20 EPX70597.1 - 1.5e-56 191.4 0.0 1.7e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70597.1 - 5.2e-20 71.6 0.0 7.7e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX70597.1 - 1.3e-05 25.0 0.1 0.00011 22.0 0.1 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPX70597.1 - 0.0091 15.5 0.1 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EPX70597.1 - 0.037 13.0 0.3 0.071 12.1 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPX70597.1 - 0.043 13.1 0.1 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APC_CDC26 PF10471.4 EPX70598.1 - 2.8e-09 37.5 1.9 6.7e-09 36.3 1.3 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Pribosyltran PF00156.22 EPX70599.1 - 1.3e-08 34.6 0.2 2.1e-07 30.6 0.2 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Cation_efflux PF01545.16 EPX70600.1 - 3.8e-74 249.3 3.2 4.5e-74 249.0 2.2 1.0 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EPX70600.1 - 0.0006 18.9 0.8 0.001 18.1 0.6 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2764 PF10962.3 EPX70600.1 - 0.1 11.8 0.0 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2764) Sin3_corepress PF08295.7 EPX70601.1 - 4.7e-36 122.5 2.1 1.9e-35 120.6 0.1 2.6 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.16 EPX70601.1 - 3.6e-18 64.8 10.5 2.2e-06 27.1 0.1 3.9 3 0 0 3 3 3 3 Paired amphipathic helix repeat BSD PF03909.12 EPX70601.1 - 0.00075 19.1 0.1 0.0019 17.9 0.1 1.8 1 0 0 1 1 1 1 BSD domain Pkinase PF00069.20 EPX70602.1 - 2.4e-72 243.2 0.0 4.1e-72 242.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70602.1 - 1.5e-41 142.2 0.0 2.8e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EPX70602.1 - 2.8e-35 120.1 1.5 3.2e-19 68.6 0.4 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EPX70602.1 - 1.5e-07 30.6 0.0 1e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPX70602.1 - 0.015 14.9 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EPX70602.1 - 0.021 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LETM1 PF07766.8 EPX70603.1 - 1.8e-94 315.7 0.1 2.4e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EPX70603.1 - 0.034 13.6 0.0 6.9 6.2 0.0 2.8 2 0 0 2 2 2 0 SAP domain MutS_V PF00488.16 EPX70604.1 - 1.1e-88 296.6 0.0 1.9e-88 295.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPX70604.1 - 4.9e-38 130.9 7.3 1.2e-37 129.7 5.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EPX70604.1 - 1.4e-19 70.1 0.0 3.5e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EPX70604.1 - 1.4e-11 44.6 0.0 2.9e-10 40.3 0.0 2.8 2 0 0 2 2 2 1 MutS domain II AAA_29 PF13555.1 EPX70604.1 - 0.026 14.0 0.0 0.064 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EPX70604.1 - 1.4 9.1 9.0 0.42 10.8 0.1 3.0 2 1 0 2 2 2 0 AAA domain TAFII55_N PF04658.8 EPX70605.1 - 3e-56 189.3 0.2 3e-56 189.3 0.2 2.0 2 1 0 2 2 2 1 TAFII55 protein conserved region Myc_N PF01056.13 EPX70605.1 - 0.41 9.7 7.5 0.79 8.8 5.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Tfb4 PF03850.9 EPX70605.1 - 1.9 7.6 4.6 13 4.8 0.0 2.1 2 0 0 2 2 2 0 Transcription factor Tfb4 Fe-ADH PF00465.14 EPX70606.1 - 3.5e-50 170.6 0.1 4.7e-50 170.2 0.1 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EPX70606.1 - 1.7e-38 132.4 0.3 2.1e-38 132.0 0.2 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EPX70606.1 - 9.9e-07 27.9 1.1 6.6e-06 25.2 0.7 2.0 1 1 0 1 1 1 1 3-dehydroquinate synthase DUF605 PF04652.11 EPX70607.1 - 1.3e-25 90.6 13.7 7.2e-13 48.6 0.0 2.1 1 1 1 2 2 2 2 Vta1 like Thioredoxin PF00085.15 EPX70608.1 - 4.4e-24 84.1 0.0 5.1e-21 74.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EPX70608.1 - 2.1e-11 43.9 1.5 1.3e-08 34.8 0.1 2.6 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EPX70608.1 - 2.3e-08 34.1 1.1 1.2e-06 28.6 0.1 2.9 3 2 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPX70608.1 - 4e-05 23.6 0.5 0.0022 18.0 0.1 3.3 2 2 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 EPX70608.1 - 0.00015 21.4 0.0 0.00034 20.2 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EPX70608.1 - 0.0016 17.9 0.0 0.0038 16.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EPX70608.1 - 0.0023 17.9 0.2 0.0079 16.1 0.0 2.0 3 0 0 3 3 3 1 Thioredoxin-like Glutaredoxin PF00462.19 EPX70608.1 - 0.0024 17.8 0.2 0.26 11.3 0.1 2.5 2 0 0 2 2 2 1 Glutaredoxin Redoxin PF08534.5 EPX70608.1 - 0.0027 17.2 0.1 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 Redoxin TraF PF13728.1 EPX70608.1 - 0.0078 15.7 0.0 0.37 10.2 0.0 2.6 2 1 0 2 2 2 1 F plasmid transfer operon protein Sec10 PF07393.6 EPX70609.1 - 3.6e-150 501.4 6.8 5e-150 501.0 4.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 FBP PF07299.6 EPX70609.1 - 0.012 14.9 1.4 5.5 6.2 0.0 3.1 3 0 0 3 3 3 0 Fibronectin-binding protein (FBP) FliD_C PF07195.7 EPX70609.1 - 2.7 7.2 12.3 0.69 9.1 2.6 2.6 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus zf-PARP PF00645.13 EPX70610.1 - 5.7e-16 58.5 0.0 9.2e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region FAD_binding_1 PF00667.15 EPX70611.1 - 6.7e-37 127.0 0.0 1e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EPX70611.1 - 3.9e-14 53.1 0.0 8.5e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Acyltransferase PF01553.16 EPX70612.1 - 0.0012 18.2 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase FTA2 PF13095.1 EPX70613.1 - 3.9e-08 33.1 0.1 5.5e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 SIR2 PF02146.12 EPX70614.1 - 1.1e-25 90.3 0.0 4.9e-25 88.2 0.0 2.0 1 1 0 1 1 1 1 Sir2 family zf-UDP PF14569.1 EPX70614.1 - 0.048 13.4 1.3 0.072 12.8 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger Zn-ribbon_8 PF09723.5 EPX70614.1 - 0.14 12.1 1.1 0.37 10.7 0.8 1.8 1 0 0 1 1 1 0 Zinc ribbon domain SNF2_N PF00176.18 EPX70615.1 - 3.1e-74 249.4 0.6 6.3e-74 248.4 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EPX70615.1 - 5.4e-24 83.6 3.7 2.5e-12 46.2 0.1 3.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EPX70615.1 - 1.1e-15 57.1 0.0 6.9e-15 54.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPX70615.1 - 2.9e-05 23.6 0.0 6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CHDCT2 PF08074.6 EPX70615.1 - 0.0026 17.4 0.0 0.0089 15.7 0.0 1.9 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain APG12 PF04110.8 EPX70616.1 - 5.2e-33 113.1 0.1 9.3e-33 112.2 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EPX70616.1 - 0.00037 20.4 0.0 0.00048 20.0 0.0 1.3 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Init_tRNA_PT PF04179.7 EPX70616.1 - 0.072 11.9 0.2 0.088 11.6 0.2 1.0 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase UPF0184 PF03670.8 EPX70616.1 - 0.11 12.7 0.2 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) PAP1 PF08601.5 EPX70617.1 - 9.2e-34 117.6 15.5 1.3e-30 107.3 7.4 4.3 1 1 1 3 3 3 2 Transcription factor PAP1 bZIP_1 PF00170.16 EPX70617.1 - 1.8e-08 34.2 11.5 5e-08 32.7 8.0 1.8 1 0 0 1 1 1 1 bZIP transcription factor Herpes_UL6 PF01763.11 EPX70617.1 - 0.018 13.2 2.7 0.023 12.8 1.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like bZIP_2 PF07716.10 EPX70617.1 - 0.024 14.4 12.8 0.14 12.0 2.8 2.5 2 0 0 2 2 2 0 Basic region leucine zipper TMPIT PF07851.8 EPX70617.1 - 0.089 11.8 1.7 0.18 10.8 1.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 EPX70617.1 - 0.3 10.6 7.1 1 8.9 4.9 1.9 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EPX70617.1 - 0.82 9.1 6.6 0.28 10.6 2.1 2.0 2 0 0 2 2 2 0 Septum formation initiator Adeno_PIX PF03955.9 EPX70617.1 - 2.1 8.9 4.5 0.97 9.9 1.3 1.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) bZIP_Maf PF03131.12 EPX70617.1 - 4.4 7.6 13.7 1.4 9.2 6.9 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Ribosomal_L15e PF00827.12 EPX70618.1 - 4.3e-89 297.1 9.0 5.1e-89 296.8 6.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 Fungal_trans PF04082.13 EPX70619.1 - 1.8e-27 95.8 0.0 3.2e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX70619.1 - 1.5e-09 37.5 13.8 1.5e-09 37.5 9.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chalcone PF02431.10 EPX70620.1 - 5.7e-37 127.0 0.2 6.9e-37 126.7 0.2 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase RFC1 PF08519.7 EPX70620.1 - 0.06 13.1 0.1 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain Chromo PF00385.19 EPX70621.1 - 3.5e-17 61.8 1.0 7.4e-17 60.7 0.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RRM_1 PF00076.17 EPX70621.1 - 2e-05 24.0 0.0 6.4e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX70621.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tudor-knot PF11717.3 EPX70621.1 - 0.026 14.2 1.3 0.067 12.9 0.9 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Ras PF00071.17 EPX70622.1 - 1.6e-63 212.8 0.8 1.9e-63 212.6 0.6 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX70622.1 - 1.9e-20 73.5 0.1 3e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX70622.1 - 1.1e-13 50.8 0.2 1.4e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EPX70622.1 - 1.8e-06 27.8 0.1 2.4e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPX70622.1 - 4.5e-05 22.9 0.2 8.6e-05 22.0 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 EPX70622.1 - 7.7e-05 21.9 0.3 9.6e-05 21.6 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 EPX70622.1 - 0.00017 20.8 0.2 0.00027 20.1 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EPX70622.1 - 0.00082 19.5 0.1 0.002 18.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPX70622.1 - 0.0013 17.9 0.0 0.0033 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EPX70622.1 - 0.022 15.0 0.3 0.032 14.5 0.2 1.5 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 EPX70622.1 - 0.024 13.8 0.0 0.037 13.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EPX70622.1 - 0.029 14.2 0.1 0.056 13.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPX70622.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3533 PF12051.3 EPX70622.1 - 0.065 11.9 0.2 0.073 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) AAA_5 PF07728.9 EPX70622.1 - 0.065 12.9 0.0 0.19 11.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.13 EPX70622.1 - 0.066 12.5 0.2 0.83 8.9 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.1 EPX70622.1 - 0.097 12.6 0.7 0.17 11.8 0.5 1.4 1 1 0 1 1 1 0 AAA domain SHMT PF00464.14 EPX70623.1 - 2.8e-203 674.6 0.0 3.3e-203 674.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EPX70623.1 - 0.022 13.9 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DUF3554 PF12074.3 EPX70624.1 - 1.4e-41 143.1 12.3 1.4e-41 143.1 8.5 5.7 5 1 1 6 6 6 1 Domain of unknown function (DUF3554) HEAT PF02985.17 EPX70624.1 - 1.3e-40 133.8 26.0 0.00065 19.5 0.0 19.8 21 0 0 21 21 21 10 HEAT repeat HEAT_2 PF13646.1 EPX70624.1 - 1.6e-38 130.8 38.3 1.3e-08 35.0 0.0 14.4 10 1 6 16 16 16 11 HEAT repeats HEAT_EZ PF13513.1 EPX70624.1 - 3.9e-29 100.3 37.3 0.00048 20.5 0.0 17.6 14 4 4 18 18 18 9 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPX70624.1 - 1.2e-12 47.9 0.0 0.22 11.9 0.0 8.1 6 2 2 8 8 8 5 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 EPX70624.1 - 2.6e-08 33.6 4.1 0.55 10.2 0.0 7.7 7 0 0 7 7 7 2 HEAT repeat associated with sister chromatid cohesion ParcG PF10274.4 EPX70624.1 - 0.00011 22.2 8.8 0.78 9.6 0.0 7.4 8 0 0 8 8 8 1 Parkin co-regulated protein HEAT_PBS PF03130.11 EPX70624.1 - 0.11 12.9 7.7 14 6.5 0.1 7.0 8 0 0 8 8 8 0 PBS lyase HEAT-like repeat Utp11 PF03998.8 EPX70625.1 - 5.8e-69 232.5 30.7 6.7e-69 232.4 21.3 1.0 1 0 0 1 1 1 1 Utp11 protein EMG1 PF03587.9 EPX70626.1 - 2e-78 262.3 0.0 3e-78 261.7 0.0 1.3 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PNRC PF15365.1 EPX70627.1 - 5.4e-05 23.1 3.2 5.4e-05 23.1 2.2 3.4 1 1 2 3 3 3 2 Proline-rich nuclear receptor coactivator MSC PF09402.5 EPX70628.1 - 5.6e-79 265.2 0.6 1e-78 264.3 0.4 1.4 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EPX70628.1 - 4.1e-09 35.8 0.0 1.1e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 HeH/LEM domain RRN3 PF05327.6 EPX70629.1 - 2.2e-153 511.3 5.2 3.2e-153 510.8 3.6 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 YniB PF14002.1 EPX70629.1 - 0.032 13.6 0.5 0.19 11.1 0.1 2.4 3 0 0 3 3 3 0 YniB-like protein Ribosomal_S7e PF01251.13 EPX70632.1 - 1.5e-82 275.6 0.3 1.7e-82 275.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e EB1 PF03271.12 EPX70633.1 - 1.1e-16 60.5 0.1 2.1e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EPX70633.1 - 2e-05 24.5 0.8 7.4e-05 22.7 0.4 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain Herpes_UL6 PF01763.11 EPX70633.1 - 0.0091 14.2 0.1 0.012 13.8 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like F-box-like_2 PF13013.1 EPX70634.1 - 2.9e-20 72.0 0.3 6.5e-20 70.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like domain zf-CCHC PF00098.18 EPX70635.1 - 3.6e-51 168.7 51.6 6.9e-08 32.0 1.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EPX70635.1 - 6e-15 54.6 43.4 0.0039 16.8 0.5 7.0 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EPX70635.1 - 1.9e-06 27.4 47.1 0.16 11.7 3.4 6.9 1 1 5 6 6 6 4 Zinc knuckle zf-CCHC_6 PF15288.1 EPX70635.1 - 0.00018 21.1 43.7 0.31 10.7 0.7 6.7 6 1 1 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.1 EPX70635.1 - 0.0059 16.0 2.2 0.0059 16.0 1.5 6.7 5 2 2 7 7 7 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.1 EPX70635.1 - 0.029 13.8 39.5 0.031 13.7 0.2 6.6 4 2 3 7 7 7 0 Zinc knuckle Methyltransf_11 PF08241.7 EPX70636.1 - 6.9e-10 39.2 0.0 1.2e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX70636.1 - 1.4e-06 28.1 0.0 2.5e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX70636.1 - 0.0037 17.5 0.0 0.0087 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX70636.1 - 0.0084 15.6 0.1 0.071 12.6 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX70636.1 - 0.12 12.8 0.2 1.2 9.6 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain BTB PF00651.26 EPX70637.1 - 3.8e-25 88.0 1.4 1e-13 51.1 0.1 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank PF00023.25 EPX70637.1 - 2e-09 36.7 0.3 1.4e-05 24.6 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EPX70637.1 - 1e-08 35.3 0.0 3e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPX70637.1 - 3.6e-08 33.6 0.0 2.6e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPX70637.1 - 3.7e-06 26.6 0.9 0.0052 16.9 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EPX70637.1 - 1.1e-05 25.4 0.0 0.0012 19.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) BACK PF07707.10 EPX70637.1 - 0.0011 18.7 0.1 0.0046 16.7 0.0 2.2 1 0 0 1 1 1 1 BTB And C-terminal Kelch Ins_P5_2-kin PF06090.7 EPX70637.1 - 0.0098 14.9 0.1 0.099 11.6 0.1 2.4 3 0 0 3 3 3 1 Inositol-pentakisphosphate 2-kinase CAP_GLY PF01302.20 EPX70638.1 - 1.6e-24 85.3 0.1 2.4e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EPX70638.1 - 7.5e-11 42.1 0.1 1.2e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain RNase_HII PF01351.13 EPX70639.1 - 1.7e-62 210.5 0.0 2.3e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII ADK PF00406.17 EPX70640.1 - 1.5e-59 200.1 0.0 1.8e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EPX70640.1 - 2.2e-15 56.0 0.0 4.8e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EPX70640.1 - 2.3e-07 31.6 0.0 4.6e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPX70640.1 - 1.5e-06 28.1 0.0 5.4e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPX70640.1 - 0.00086 19.6 0.4 0.0051 17.1 0.1 2.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPX70640.1 - 0.0018 17.4 0.1 0.0035 16.4 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin Thymidylate_kin PF02223.12 EPX70640.1 - 0.025 13.9 0.1 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase CTD_bind PF04818.8 EPX70641.1 - 0.0021 18.2 0.0 0.0066 16.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.14 EPX70641.1 - 0.0042 16.7 0.0 0.013 15.0 0.0 1.9 1 0 0 1 1 1 1 VHS domain DUF1460 PF07313.7 EPX70641.1 - 0.15 11.2 0.2 0.28 10.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) zf-C2H2_4 PF13894.1 EPX70641.1 - 0.16 12.3 5.2 6.2 7.3 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EPX70641.1 - 1.4 8.6 9.8 8.2 6.2 0.2 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type PUF PF00806.14 EPX70642.1 - 2.7e-39 130.4 12.9 6.2e-07 28.5 0.1 8.4 9 0 0 9 9 9 6 Pumilio-family RNA binding repeat Bcl-2 PF00452.14 EPX70642.1 - 0.0015 18.6 3.6 0.14 12.3 0.3 3.9 2 1 1 3 3 3 1 Apoptosis regulator proteins, Bcl-2 family CHZ PF09649.5 EPX70643.1 - 3.9e-11 41.9 0.3 3.9e-11 41.9 0.2 2.4 3 0 0 3 3 3 1 Histone chaperone domain CHZ UPF0300 PF08594.5 EPX70644.1 - 2.9e-69 232.2 0.6 2.9e-69 232.2 0.4 1.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0300) RNA_pol_Rpb2_6 PF00562.23 EPX70645.1 - 5.4e-121 403.9 0.0 9.4e-121 403.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPX70645.1 - 1.1e-64 217.0 0.1 1.1e-63 213.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EPX70645.1 - 9.4e-40 136.0 0.1 3.3e-39 134.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EPX70645.1 - 9.5e-30 102.6 0.1 2.8e-29 101.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EPX70645.1 - 3e-26 91.0 0.3 1.1e-25 89.2 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EPX70645.1 - 9e-19 67.0 0.1 1.9e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EPX70645.1 - 2.1e-14 53.1 1.8 6.1e-14 51.7 1.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 EPX70645.1 - 0.015 13.6 0.1 0.029 12.7 0.0 1.3 1 0 0 1 1 1 0 Baculovirus Y142 protein PQQ PF01011.16 EPX70645.1 - 0.12 11.9 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat DUF619 PF04768.8 EPX70646.1 - 1.9e-36 125.0 0.1 7.8e-36 123.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EPX70646.1 - 5.1e-28 97.8 0.0 1.1e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EPX70646.1 - 1.1e-22 80.7 0.5 8e-22 77.9 0.1 2.1 2 0 0 2 2 2 1 Amino acid kinase family DapB_N PF01113.15 EPX70646.1 - 0.0022 17.8 0.0 0.0055 16.6 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus OTCace PF00185.19 EPX70647.1 - 1.3e-45 155.0 0.1 1.9e-45 154.6 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EPX70647.1 - 1.7e-42 144.4 0.0 2.6e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain HMG_box PF00505.14 EPX70648.1 - 4.7e-09 36.3 5.9 2.2e-08 34.2 0.4 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPX70648.1 - 5.5e-09 36.2 2.2 1.8e-08 34.5 0.1 2.3 2 0 0 2 2 2 1 HMG-box domain Phe_tRNA-synt_N PF02912.13 EPX70648.1 - 0.0023 17.5 2.5 0.34 10.6 0.1 2.4 2 0 0 2 2 2 2 Aminoacyl tRNA synthetase class II, N-terminal domain DUF1104 PF06518.6 EPX70648.1 - 0.034 14.2 6.7 0.62 10.2 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) DUF3106 PF11304.3 EPX70648.1 - 0.066 13.6 5.3 5.4 7.4 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) Rabaptin PF03528.10 EPX70648.1 - 0.071 13.0 2.5 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 Rabaptin Med30 PF11315.3 EPX70648.1 - 0.073 13.2 0.9 2.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 30 DUF2203 PF09969.4 EPX70648.1 - 0.16 12.2 1.2 13 6.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Enkurin PF13864.1 EPX70648.1 - 1.3 9.2 7.1 1.6 9.0 0.3 2.4 2 1 0 2 2 2 0 Calmodulin-binding AAA_33 PF13671.1 EPX70649.1 - 3.7e-12 46.3 0.0 5.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPX70649.1 - 6.1e-12 46.4 0.0 9.5e-12 45.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 EPX70649.1 - 3.3e-11 43.2 0.1 6.9e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 EPX70649.1 - 1.7e-09 38.0 0.1 7.2e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPX70649.1 - 1.4e-05 25.2 0.0 3.7e-05 23.8 0.0 1.7 1 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPX70649.1 - 0.00014 22.1 0.0 0.00021 21.5 0.0 1.7 1 1 0 1 1 1 1 ABC transporter APS_kinase PF01583.15 EPX70649.1 - 0.00029 20.5 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.24 EPX70649.1 - 0.00065 19.9 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EPX70649.1 - 0.0012 18.4 0.8 0.0056 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 EPX70649.1 - 0.0013 18.1 0.3 0.31 10.4 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase Cytidylate_kin2 PF13189.1 EPX70649.1 - 0.0013 18.6 0.4 0.031 14.1 0.0 2.4 2 1 1 3 3 3 1 Cytidylate kinase-like family AAA_14 PF13173.1 EPX70649.1 - 0.0013 18.6 0.1 0.011 15.6 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.1 EPX70649.1 - 0.0014 18.0 0.0 0.0018 17.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPX70649.1 - 0.0017 17.4 0.1 0.0088 15.1 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin Rad17 PF03215.10 EPX70649.1 - 0.0023 16.6 0.0 0.0036 16.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 EPX70649.1 - 0.003 17.0 0.0 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain T2SE PF00437.15 EPX70649.1 - 0.0032 16.3 0.0 0.055 12.3 0.0 2.4 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_23 PF13476.1 EPX70649.1 - 0.0033 17.7 0.3 0.018 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EPX70649.1 - 0.0044 16.9 0.0 0.033 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPX70649.1 - 0.0051 16.3 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ADK PF00406.17 EPX70649.1 - 0.0068 16.2 0.8 0.22 11.3 0.0 2.6 2 1 0 2 2 2 1 Adenylate kinase AAA_16 PF13191.1 EPX70649.1 - 0.0071 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EPX70649.1 - 0.0072 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EPX70649.1 - 0.0074 16.4 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 EPX70649.1 - 0.008 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 EPX70649.1 - 0.0085 15.3 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein Elong_Iki1 PF10483.4 EPX70649.1 - 0.012 15.0 0.1 0.014 14.7 0.1 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 UPF0079 PF02367.12 EPX70649.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EPX70649.1 - 0.015 15.0 0.2 0.062 12.9 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase MobB PF03205.9 EPX70649.1 - 0.015 14.9 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_2 PF07724.9 EPX70649.1 - 0.028 14.3 0.1 0.066 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) DUF258 PF03193.11 EPX70649.1 - 0.029 13.5 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EPX70649.1 - 0.033 13.8 0.0 0.088 12.5 0.0 1.7 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.12 EPX70649.1 - 0.036 13.4 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.1 EPX70649.1 - 0.041 13.4 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EPX70649.1 - 0.052 12.5 0.1 0.24 10.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 EPX70649.1 - 0.058 12.3 0.0 0.12 11.3 0.0 1.5 1 1 1 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.1 EPX70649.1 - 0.066 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 EPX70649.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.4 EPX70649.1 - 0.069 12.6 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.7 EPX70649.1 - 0.072 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Vps26 PF03643.10 EPX70650.1 - 1.5e-127 424.0 4.8 1.7e-127 423.9 3.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EPX70650.1 - 0.0035 17.1 3.6 0.045 13.5 0.3 3.3 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Mpv17_PMP22 PF04117.7 EPX70651.1 - 1.7e-23 82.0 5.0 2.8e-23 81.3 3.4 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family CTP_transf_1 PF01148.15 EPX70651.1 - 0.42 10.2 8.5 0.4 10.3 0.2 2.2 2 0 0 2 2 2 0 Cytidylyltransferase family adh_short PF00106.20 EPX70652.1 - 2.2e-24 86.2 0.0 3.4e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPX70652.1 - 2.6e-08 33.9 0.0 4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPX70652.1 - 4.8e-07 29.6 0.0 9.1e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPX70652.1 - 0.0016 18.5 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPX70652.1 - 0.018 14.4 0.1 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPX70652.1 - 0.031 13.1 0.2 0.043 12.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EPX70652.1 - 0.044 14.2 0.1 0.088 13.2 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EPX70652.1 - 0.046 13.8 0.3 0.11 12.6 0.2 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L6 PF00347.18 EPX70653.1 - 2e-33 114.7 2.9 4e-18 65.6 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S5_C PF03719.10 EPX70654.1 - 7.2e-20 70.0 0.0 1.3e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EPX70654.1 - 1.3e-12 47.2 0.6 2.8e-12 46.1 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain DnaJ PF00226.26 EPX70655.1 - 8.8e-16 57.3 0.6 1.5e-15 56.6 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain COX14 PF14880.1 EPX70655.1 - 0.024 14.2 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Mito_carr PF00153.22 EPX70656.1 - 2.8e-68 225.6 3.0 1.3e-24 85.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltrans PF00432.16 EPX70657.1 - 5.3e-31 105.8 4.8 2.2e-09 36.7 0.1 5.6 6 1 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPX70657.1 - 4e-27 94.8 0.1 2.6e-13 50.3 0.1 4.6 4 1 1 5 5 5 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPX70657.1 - 4e-27 94.3 0.0 1.2e-11 44.5 0.0 5.7 3 1 3 6 6 6 4 Prenyltransferase-like Pec_lyase PF09492.5 EPX70657.1 - 2.3e-10 40.1 0.1 0.0075 15.4 0.1 4.0 2 2 3 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 EPX70657.1 - 0.00059 19.1 1.8 0.41 9.8 0.0 4.0 3 1 1 5 5 5 1 A-macroglobulin complement component Mago-bind PF09282.5 EPX70657.1 - 0.019 14.5 0.2 0.47 10.0 0.0 2.6 2 0 0 2 2 2 0 Mago binding HSP70 PF00012.15 EPX70658.1 - 1.6e-271 901.5 6.2 1.9e-271 901.3 4.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPX70658.1 - 1.8e-17 62.9 0.1 4.2e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EPX70658.1 - 0.00055 19.5 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Ppx-GppA PF02541.11 EPX70658.1 - 0.01 15.0 0.6 0.019 14.1 0.0 1.7 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Hydantoinase_A PF01968.13 EPX70658.1 - 0.023 13.8 0.1 0.11 11.5 0.0 2.1 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase Smg4_UPF3 PF03467.10 EPX70659.1 - 3.7e-30 105.2 6.0 2.4e-29 102.5 0.1 2.9 3 1 0 3 3 3 2 Smg-4/UPF3 family RRM_6 PF14259.1 EPX70659.1 - 0.044 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SUR7 PF06687.7 EPX70660.1 - 1.3e-14 54.2 17.2 2.1e-14 53.6 11.9 1.3 1 0 0 1 1 1 1 SUR7/PalI family MBOAT PF03062.14 EPX70661.1 - 1.2e-43 149.5 27.1 1.2e-43 149.5 18.8 2.4 1 1 2 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EPX70661.1 - 1.4e-06 28.2 4.5 1.4e-06 28.2 3.1 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family PAPS_reduct PF01507.14 EPX70662.1 - 1.9e-45 154.7 0.0 2.5e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF1043 PF06295.7 EPX70662.1 - 0.06 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Arb2 PF09757.4 EPX70663.1 - 1.5e-08 34.2 0.1 2.6e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Arb2 domain WD40 PF00400.27 EPX70664.1 - 1.1e-13 50.4 14.9 3.1e-05 23.6 0.1 4.9 5 1 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EPX70664.1 - 3.1e-05 22.3 0.1 4.8e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPX70664.1 - 0.003 16.3 9.4 0.0095 14.7 2.2 3.3 1 1 3 4 4 4 3 Nup133 N terminal like Hira PF07569.6 EPX70664.1 - 0.023 13.9 0.2 0.31 10.2 0.0 2.6 3 0 0 3 3 3 0 TUP1-like enhancer of split FliJ PF02050.11 EPX70665.1 - 0.13 12.2 1.5 0.21 11.6 1.0 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein PGA2 PF07543.7 EPX70665.1 - 0.33 10.7 7.1 0.37 10.5 4.6 1.4 1 1 0 1 1 1 0 Protein trafficking PGA2 Apt1 PF10351.4 EPX70665.1 - 3.2 6.4 7.8 3.5 6.3 5.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain BNIP3 PF06553.7 EPX70665.1 - 4 6.7 11.1 0.2 10.9 3.6 1.6 1 1 1 2 2 2 0 BNIP3 Myb_DNA-binding PF00249.26 EPX70666.1 - 2e-18 66.1 0.4 3.9e-08 33.2 0.0 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPX70666.1 - 4.9e-15 55.3 0.0 1.6e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Chorion_2 PF03964.10 EPX70666.1 - 0.0088 16.5 1.0 0.017 15.6 0.7 1.4 1 0 0 1 1 1 1 Chorion family 2 MBA1 PF07961.6 EPX70667.1 - 3e-41 140.8 0.8 3.8e-41 140.4 0.6 1.0 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 EPX70667.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain EF1G PF00647.14 EPX70667.1 - 0.046 13.4 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain Choline_kinase PF01633.15 EPX70668.1 - 4e-53 180.1 0.6 5.4e-53 179.7 0.4 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EPX70668.1 - 9.1e-08 32.1 0.0 2.5e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kin_N PF04428.9 EPX70668.1 - 0.00016 21.0 1.0 0.00037 19.9 0.1 1.9 2 0 0 2 2 2 1 Choline kinase N terminus RRM_5 PF13893.1 EPX70669.1 - 5.4e-22 77.3 0.0 1e-09 38.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX70669.1 - 8e-22 76.6 0.1 1.1e-08 34.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX70669.1 - 1e-17 63.8 0.1 1.4e-06 28.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPX70669.1 - 0.002 17.9 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EPX70669.1 - 0.12 12.1 0.0 15 5.4 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF2076 PF09849.4 EPX70670.1 - 3e-07 30.7 13.0 3.8e-07 30.4 9.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EPX70670.1 - 0.00084 19.1 5.3 0.0014 18.4 3.7 1.4 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 EPX70670.1 - 0.1 12.6 2.7 0.25 11.3 1.8 1.5 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Citrate_synt PF00285.16 EPX70671.1 - 6e-97 324.5 0.0 1.4e-96 323.3 0.0 1.5 2 0 0 2 2 2 1 Citrate synthase DUF627 PF04781.7 EPX70672.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF627) E1-E2_ATPase PF00122.15 EPX70673.1 - 1.1e-23 83.4 0.0 2.7e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EPX70673.1 - 1.4e-13 51.7 0.0 3.8e-12 47.0 0.0 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPX70673.1 - 4.3e-11 43.3 0.0 1.1e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPX70673.1 - 1.7e-07 31.1 0.0 5.6e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPX70673.1 - 0.00085 18.9 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.1 EPX70673.1 - 0.013 14.2 0.4 0.028 13.2 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Syntaphilin PF15290.1 EPX70674.1 - 0.00025 20.6 5.9 0.00025 20.6 4.1 2.2 2 1 1 3 3 3 1 Golgi-localised syntaxin-1-binding clamp Ank_2 PF12796.2 EPX70675.1 - 6.3e-46 154.6 0.5 3e-17 62.7 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPX70675.1 - 7.5e-35 118.6 1.1 5.9e-10 39.4 0.0 4.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EPX70675.1 - 2.2e-32 109.2 0.1 1.2e-06 28.0 0.0 5.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EPX70675.1 - 9.8e-31 105.0 0.2 7.5e-09 35.5 0.0 4.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPX70675.1 - 2.9e-26 88.9 0.0 7.9e-05 22.5 0.0 5.6 6 0 0 6 6 6 5 Ankyrin repeat Ribonuc_P_40 PF08584.6 EPX70676.1 - 1.2e-18 67.1 0.0 1.6e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit RNA_lig_T4_1 PF09511.5 EPX70677.1 - 6.5e-79 264.4 1.6 1e-78 263.8 1.1 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 EPX70677.1 - 6.6e-50 169.7 0.7 1.1e-49 168.9 0.0 1.6 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 EPX70677.1 - 2.5e-46 157.5 0.0 7.2e-46 156.1 0.0 1.8 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 EPX70677.1 - 0.0013 19.5 0.0 0.0067 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPX70677.1 - 0.029 14.6 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain IU_nuc_hydro PF01156.14 EPX70678.1 - 9.8e-94 314.0 2.4 1.1e-93 313.8 1.6 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CBFD_NFYB_HMF PF00808.18 EPX70679.1 - 9.5e-15 54.4 1.8 2.8e-14 52.9 1.2 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPX70679.1 - 4.1e-08 33.2 0.4 7.2e-08 32.4 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SAGA-Tad1 PF12767.2 EPX70679.1 - 0.72 9.4 12.4 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2215 PF10225.4 EPX70679.1 - 0.78 9.1 6.0 1.2 8.4 4.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Pox_Ag35 PF03286.9 EPX70679.1 - 1.7 8.0 21.6 0.39 10.2 12.6 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein vMSA PF00695.14 EPX70679.1 - 7.9 5.5 10.8 9 5.3 7.0 1.3 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus Hid1 PF12722.2 EPX70679.1 - 9.1 3.8 14.6 11 3.4 10.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CBFD_NFYB_HMF PF00808.18 EPX70680.1 - 3.8e-06 26.8 0.0 4.8e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPX70680.1 - 0.011 15.8 0.1 0.015 15.3 0.1 1.4 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 P16-Arc PF04699.9 EPX70681.1 - 1.2e-39 135.7 0.0 1.3e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Med20 PF08612.6 EPX70682.1 - 3.1e-18 65.7 0.1 4.3e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex ILVD_EDD PF00920.16 EPX70683.1 - 9.4e-209 694.1 0.3 1.1e-208 693.9 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family YEATS PF03366.11 EPX70684.1 - 3.9e-32 109.7 0.5 8.7e-32 108.6 0.3 1.6 1 0 0 1 1 1 1 YEATS family UPF0016 PF01169.14 EPX70685.1 - 1.4e-38 130.8 22.8 1.1e-21 76.7 3.3 2.5 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 Nitrate_red_gam PF02665.9 EPX70685.1 - 0.1 11.9 0.2 0.1 11.9 0.2 2.1 2 1 0 3 3 3 0 Nitrate reductase gamma subunit DUF204 PF02659.10 EPX70685.1 - 3.6 7.7 13.2 0.32 11.1 2.7 3.0 2 1 0 2 2 2 0 Domain of unknown function DUF COMPASS-Shg1 PF05205.7 EPX70686.1 - 1.1e-19 70.6 0.8 1.4e-19 70.3 0.5 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Clathrin PF00637.15 EPX70686.1 - 0.018 14.6 0.1 0.022 14.3 0.1 1.3 1 1 0 1 1 1 0 Region in Clathrin and VPS FHA PF00498.21 EPX70687.1 - 4.7e-18 65.0 0.1 7.4e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EPX70687.1 - 1.3e-05 24.8 14.8 2.5e-05 23.9 9.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EPX70687.1 - 0.00011 22.2 5.3 0.0009 19.3 3.0 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPX70687.1 - 0.0095 15.7 4.2 0.026 14.3 2.9 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EPX70687.1 - 0.036 13.8 11.0 0.081 12.6 7.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 EPX70687.1 - 0.27 10.9 10.4 0.28 10.8 5.9 2.0 2 0 0 2 2 2 0 PHD-finger zf-C3HC4 PF00097.20 EPX70687.1 - 0.96 9.1 15.2 1 9.0 9.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPX70687.1 - 2 8.5 16.5 2.1 8.4 10.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Gly_transf_sug PF04488.10 EPX70688.1 - 1.8e-24 86.1 0.0 3.2e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EPX70688.1 - 0.0039 15.7 1.5 0.01 14.3 0.1 1.9 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EPX70688.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Phage_XkdX PF09693.5 EPX70688.1 - 0.069 12.6 0.4 0.13 11.7 0.3 1.4 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) DUF3328 PF11807.3 EPX70688.1 - 0.1 12.2 1.9 0.84 9.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) OppC_N PF12911.2 EPX70688.1 - 4.5 6.7 7.6 0.88 8.9 0.1 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Sec3_C_2 PF15278.1 EPX70689.1 - 8.5e-22 77.0 5.0 1.9e-21 75.9 3.5 1.6 1 0 0 1 1 1 1 Sec3 exocyst complex subunit Sec3-PIP2_bind PF15277.1 EPX70689.1 - 3.7e-14 52.3 0.0 7.4e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.4 EPX70689.1 - 2.9e-05 22.4 1.6 2.9e-05 22.4 1.1 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec3 MOZ_SAS PF01853.13 EPX70690.1 - 4.2e-83 277.2 2.0 6.9e-83 276.5 1.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family He_PIG_assoc PF10632.4 EPX70690.1 - 0.093 12.0 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Pkinase PF00069.20 EPX70691.1 - 2.7e-67 226.6 0.0 5.4e-67 225.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70691.1 - 4.1e-39 134.2 0.0 8e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EPX70691.1 - 8e-22 76.7 8.8 2.8e-11 42.9 0.9 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EPX70691.1 - 8.2e-19 67.0 28.4 1.4e-10 40.7 5.4 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EPX70691.1 - 6.3e-07 29.8 0.3 6.3e-07 29.8 0.2 2.5 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPX70691.1 - 0.0012 17.9 0.0 0.0022 17.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 EPX70691.1 - 0.0024 17.6 0.1 0.0058 16.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain PHD PF00628.24 EPX70691.1 - 0.52 10.0 25.1 0.014 15.0 3.6 2.5 2 0 0 2 2 2 0 PHD-finger DUF4452 PF14618.1 EPX70692.1 - 8.4e-14 51.7 3.4 1.1e-13 51.3 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) DUF137 PF02006.11 EPX70692.1 - 0.0032 16.8 0.0 0.0046 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF137 Hamartin PF04388.7 EPX70692.1 - 0.13 10.8 0.6 0.14 10.7 0.4 1.0 1 0 0 1 1 1 0 Hamartin protein IBN_N PF03810.14 EPX70693.1 - 1.4e-11 44.1 0.0 2.7e-10 40.0 0.0 3.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.17 EPX70693.1 - 1e-05 25.2 3.2 1.3 9.2 0.0 6.8 6 0 0 6 6 6 1 HEAT repeat Arm PF00514.18 EPX70693.1 - 0.0055 16.4 0.8 7.8 6.4 0.0 4.1 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Xpo1 PF08389.7 EPX70693.1 - 0.021 14.7 0.1 0.021 14.7 0.0 5.0 6 2 0 6 6 6 0 Exportin 1-like protein Metallophos PF00149.23 EPX70694.1 - 5.8e-44 149.8 0.2 7.2e-44 149.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Clp1 PF06807.9 EPX70695.1 - 2.5e-20 73.0 0.0 1.3e-19 70.6 0.0 1.9 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EPX70695.1 - 2.5e-09 36.9 0.0 5.4e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EPX70695.1 - 0.0046 16.5 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EPX70695.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 EPX70695.1 - 0.041 13.1 0.1 0.84 8.8 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 EPX70695.1 - 0.07 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPX70695.1 - 0.1 12.9 0.0 15 5.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EPX70695.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain SH3_1 PF00018.23 EPX70697.1 - 4.7e-28 96.3 0.0 1.4e-14 53.2 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EPX70697.1 - 2.6e-17 62.0 0.1 1.4e-10 40.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 EPX70697.1 - 1.2e-14 53.6 0.0 5.1e-09 35.5 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EPX70697.1 - 2.7e-11 43.2 0.0 6.1e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 EPX70697.1 - 6.7e-05 22.4 0.0 0.00016 21.2 0.0 1.6 1 0 0 1 1 1 1 PB1 domain SH3_3 PF08239.6 EPX70697.1 - 0.063 13.4 0.0 0.41 10.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain DUF2009 PF09418.5 EPX70698.1 - 4e-206 685.2 0.2 4.5e-206 685.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) LRR_4 PF12799.2 EPX70700.1 - 2.7e-11 42.8 33.3 3.2e-06 26.6 0.8 6.5 4 3 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPX70700.1 - 6.9e-07 28.9 27.9 0.00035 20.2 2.7 4.5 4 1 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 EPX70700.1 - 8.5e-06 25.4 8.1 0.087 12.3 0.2 3.5 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.1 EPX70700.1 - 0.0088 16.0 23.1 4.9 7.5 0.0 8.9 9 1 1 10 10 10 2 Leucine Rich repeat LRR_1 PF00560.28 EPX70700.1 - 0.62 10.3 25.2 10 6.5 0.3 7.8 6 4 2 8 8 8 0 Leucine Rich Repeat CRF1 PF10380.4 EPX70701.1 - 5.8e-18 65.3 7.0 5.8e-18 65.3 4.9 3.2 2 2 0 2 2 2 1 Transcription factor CRF1 GDI PF00996.13 EPX70702.1 - 2.1e-219 728.2 0.0 2.4e-219 728.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.19 EPX70702.1 - 0.038 13.0 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Hormone_2 PF00123.15 EPX70702.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Peptide hormone NYN PF01936.13 EPX70702.1 - 0.12 12.6 0.1 0.57 10.4 0.0 2.1 2 1 0 2 2 2 0 NYN domain WD40 PF00400.27 EPX70703.1 - 1.2e-34 116.9 8.7 3.2e-10 39.4 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EPX70703.1 - 5.2e-06 26.2 0.7 0.4 10.3 0.1 3.7 1 1 2 3 3 3 2 Transcription factor IIIC subunit delta N-term NTF2 PF02136.15 EPX70704.1 - 1.6e-36 125.2 0.5 1.8e-36 125.1 0.4 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 EPX70704.1 - 0.019 15.1 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF4518 PF15008.1 EPX70704.1 - 0.022 13.8 0.4 0.081 11.9 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Pkinase PF00069.20 EPX70705.1 - 2.5e-69 233.3 0.0 3.5e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70705.1 - 1.8e-28 99.3 0.0 2.9e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EPX70705.1 - 2.3e-11 44.0 5.2 9.1e-11 42.1 3.6 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPX70705.1 - 6.4e-07 28.6 0.0 1.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 EPX70705.1 - 0.00085 19.1 0.4 0.0061 16.3 0.0 2.6 2 1 0 2 2 2 1 C2 domain Brix PF04427.13 EPX70706.1 - 3.4e-54 183.4 0.3 5.5e-54 182.7 0.2 1.3 1 0 0 1 1 1 1 Brix domain SUZ-C PF12901.2 EPX70706.1 - 0.1 12.2 0.1 12 5.6 0.2 2.5 2 0 0 2 2 2 0 SUZ-C motif U79_P34 PF03064.11 EPX70706.1 - 2.9 7.3 13.5 4.4 6.7 9.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Atrophin-1 PF03154.10 EPX70706.1 - 7.1 4.6 13.6 14 3.6 9.4 1.4 1 0 0 1 1 1 0 Atrophin-1 family Mus7 PF09462.5 EPX70707.1 - 7.9e-115 385.0 17.5 1.4e-114 384.2 12.1 1.4 1 0 0 1 1 1 1 Mus7/MMS22 family HbrB PF08539.6 EPX70708.1 - 3.4e-28 98.4 1.6 5.2e-28 97.8 1.1 1.3 1 0 0 1 1 1 1 HbrB-like Gon7 PF08738.5 EPX70709.1 - 0.052 13.5 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 Gon7 family Aminotran_1_2 PF00155.16 EPX70710.1 - 3.1e-68 230.3 0.0 3.5e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EPX70710.1 - 3.9e-07 29.4 0.0 6.6e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EPX70710.1 - 6.6e-06 25.4 0.0 1.1e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EPX70710.1 - 0.00011 20.6 0.1 0.00021 19.7 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EPX70710.1 - 0.00038 19.3 0.1 0.0044 15.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 EPX70710.1 - 0.13 10.8 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain PAPA-1 PF04795.7 EPX70711.1 - 2.5e-24 85.7 3.8 2.5e-24 85.7 2.6 3.3 2 1 1 3 3 3 1 PAPA-1-like conserved region Neugrin PF06413.6 EPX70712.1 - 3.4e-06 27.0 0.1 3.9e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EPX70712.1 - 0.00094 19.1 0.4 0.0018 18.2 0.3 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Sigma70_r4 PF04545.11 EPX70712.1 - 0.083 12.2 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 SPX PF03105.14 EPX70713.1 - 2.1e-31 109.7 7.6 2.9e-31 109.2 5.3 1.2 1 0 0 1 1 1 1 SPX domain zf-RING_2 PF13639.1 EPX70713.1 - 3.1e-07 30.1 9.6 7e-07 28.9 6.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EPX70713.1 - 4.6e-06 26.4 11.4 6.7e-06 25.8 7.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EPX70713.1 - 1.2e-05 24.8 7.1 2.5e-05 23.8 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX70713.1 - 3.4e-05 23.4 9.8 8.7e-05 22.0 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPX70713.1 - 6.8e-05 22.8 11.0 0.00019 21.3 7.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX70713.1 - 0.00055 19.5 7.9 0.0014 18.3 5.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EPX70713.1 - 0.0017 18.0 3.4 0.0043 16.7 2.4 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EPX70713.1 - 0.0071 15.8 4.0 0.023 14.2 2.8 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EPX70713.1 - 0.014 14.9 2.1 0.038 13.5 1.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EPX70713.1 - 0.13 12.3 8.5 0.61 10.2 5.9 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EPX70713.1 - 0.16 11.8 3.9 0.11 12.3 1.2 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EPX70713.1 - 2.4 7.7 9.9 6 6.4 6.2 2.0 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger DnaJ PF00226.26 EPX70714.1 - 6.5e-22 77.0 0.3 1.8e-21 75.6 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 EPX70714.1 - 7.1e-08 32.3 5.5 1.8e-07 31.0 3.8 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EPX70714.1 - 7e-06 26.0 1.2 7e-06 26.0 0.8 2.0 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EPX70714.1 - 3e-05 24.0 4.0 6.2e-05 23.0 2.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EPX70714.1 - 0.052 13.9 2.2 0.15 12.4 1.5 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPX70714.1 - 0.11 12.4 1.2 0.27 11.1 0.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EPX70714.1 - 1.6 9.2 4.9 0.6 10.5 1.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Rsa3 PF14615.1 EPX70715.1 - 1.5e-08 33.8 0.0 2.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Ribosome-assembly protein 3 tRNA_m1G_MT PF01746.16 EPX70716.1 - 8.3e-46 155.9 0.1 1.4e-45 155.1 0.1 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DNA_primase_S PF01896.14 EPX70717.1 - 1.5e-57 193.4 0.0 2.3e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Drc1-Sld2 PF11719.3 EPX70718.1 - 8.4e-43 147.0 36.2 3.8e-28 98.7 11.1 2.2 1 1 1 2 2 2 2 DNA replication and checkpoint protein Fe-S_assembly PF04384.8 EPX70718.1 - 0.0079 16.5 0.3 4 7.8 0.3 2.5 2 0 0 2 2 2 2 Iron-sulphur cluster assembly DUF3125 PF11323.3 EPX70718.1 - 0.011 15.4 1.0 5.3 6.9 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3125) IncA PF04156.9 EPX70718.1 - 1.6 8.2 8.0 0.15 11.6 2.3 1.7 2 0 0 2 2 2 0 IncA protein TPR_11 PF13414.1 EPX70719.1 - 3.4e-45 151.5 20.0 2.8e-15 55.7 0.1 7.3 2 2 5 8 8 8 7 TPR repeat TPR_1 PF00515.23 EPX70719.1 - 3.4e-30 102.3 18.7 7.5e-06 25.3 0.0 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.12 EPX70719.1 - 3.4e-29 98.3 18.4 3.4e-05 23.4 0.0 10.5 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 EPX70719.1 - 4.7e-25 87.6 3.2 0.00043 20.8 0.5 6.4 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EPX70719.1 - 5.1e-19 67.9 17.1 2.3e-05 24.2 0.6 7.3 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 EPX70719.1 - 9.7e-16 56.6 6.1 0.051 13.7 0.0 8.5 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPX70719.1 - 2.2e-13 48.9 18.1 0.24 11.2 0.0 10.0 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPX70719.1 - 2.6e-12 46.2 9.2 0.53 11.0 0.0 9.0 6 3 4 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPX70719.1 - 1e-09 38.6 12.7 0.00013 22.2 1.4 5.6 4 2 2 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EPX70719.1 - 2.6e-09 37.0 18.2 0.0048 16.9 1.0 5.2 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EPX70719.1 - 2.6e-08 33.0 9.7 0.038 13.7 0.2 7.3 6 1 1 7 7 7 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EPX70719.1 - 7.1e-06 25.1 1.5 0.06 12.5 0.1 3.9 4 0 0 4 4 4 2 SHNi-TPR TPR_9 PF13371.1 EPX70719.1 - 1.5e-05 24.7 4.2 0.02 14.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EPX70719.1 - 0.0069 16.2 3.9 2.9 7.9 0.3 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 EPX70719.1 - 0.035 14.5 0.5 37 5.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPX70719.1 - 0.07 13.6 17.6 0.97 10.0 0.0 7.2 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 EPX70719.1 - 0.14 11.9 16.5 2.9 7.8 0.2 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat CDC45 PF02724.9 EPX70719.1 - 0.21 9.5 10.8 0.36 8.8 7.5 1.3 1 0 0 1 1 1 0 CDC45-like protein PPI_Ypi1 PF07491.6 EPX70720.1 - 1.5e-26 91.7 3.8 2.2e-26 91.2 2.6 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor DUF755 PF05501.6 EPX70720.1 - 0.14 12.1 4.3 0.2 11.7 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF4588 PF15251.1 EPX70721.1 - 0.0042 17.0 2.6 0.0059 16.6 0.9 1.6 1 1 0 2 2 2 1 Domain of unknown function (DUF4588) WD40 PF00400.27 EPX70722.1 - 1.5e-66 218.0 33.7 1.9e-13 49.6 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EPX70722.1 - 1.9e-06 26.3 4.9 0.099 10.7 0.1 3.7 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPX70722.1 - 0.0011 17.7 3.2 0.4 9.3 0.0 3.2 2 1 1 3 3 3 2 Nup133 N terminal like eIF2A PF08662.6 EPX70722.1 - 0.0013 18.4 0.5 1.2 8.8 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EPX70722.1 - 0.003 15.8 0.0 1.4 7.1 0.0 2.5 2 1 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 EPX70722.1 - 0.19 11.4 2.2 3.7 7.3 0.0 3.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF4451 PF14616.1 EPX70724.1 - 5.3e-28 97.2 3.9 1.3e-27 96.0 2.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) eIF-5_eIF-2B PF01873.12 EPX70725.1 - 3.1e-46 156.0 0.2 4.7e-46 155.5 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EPX70725.1 - 0.00013 21.2 0.2 0.00028 20.1 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding IF2_N PF04760.10 EPX70725.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region DUF1708 PF08101.6 EPX70726.1 - 2.2e-71 240.9 9.5 2.2e-71 240.9 6.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) DUF4449 PF14613.1 EPX70727.1 - 3.7e-38 131.0 0.6 3.7e-38 131.0 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) FBPase PF00316.15 EPX70727.1 - 0.033 13.0 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase CorA PF01544.13 EPX70727.1 - 0.42 9.6 5.9 0.058 12.4 0.7 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Homeobox PF00046.24 EPX70728.1 - 9.8e-17 60.3 0.7 2.3e-16 59.1 0.5 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EPX70728.1 - 0.015 14.9 0.3 0.036 13.7 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain Trp_syntA PF00290.15 EPX70729.1 - 1.4e-83 279.4 0.1 2.2e-83 278.7 0.1 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EPX70729.1 - 2.1e-47 161.8 0.1 3.6e-47 161.0 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KRAP_IP3R_bind PF14722.1 EPX70729.1 - 0.037 13.5 0.0 0.2 11.2 0.0 2.1 2 1 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain PTH2 PF01981.11 EPX70730.1 - 7.6e-45 151.3 0.2 1e-44 150.9 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 U1snRNP70_N PF12220.3 EPX70731.1 - 4.3e-29 100.6 4.0 6.9e-29 100.0 2.8 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EPX70731.1 - 5.3e-18 64.4 0.0 8.2e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX70731.1 - 4.2e-14 52.2 0.0 6.8e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX70731.1 - 7.9e-09 35.2 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Caprin-1_C PF12287.3 EPX70731.1 - 5.4 6.3 6.4 8.6 5.6 4.4 1.3 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term DCP2 PF05026.8 EPX70732.1 - 1.1e-36 124.6 1.1 2.2e-36 123.6 0.7 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EPX70732.1 - 1.1e-15 57.5 0.0 2.1e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain zf-RING_5 PF14634.1 EPX70733.1 - 1.7e-06 27.6 6.2 2.5e-06 27.0 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPX70733.1 - 7.6e-05 22.6 3.5 0.00018 21.4 2.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPX70733.1 - 0.0022 17.7 4.7 0.0036 17.0 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPX70733.1 - 0.018 14.6 7.2 0.039 13.6 5.0 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CHY PF05495.7 EPX70733.1 - 0.028 14.5 3.1 0.048 13.8 2.2 1.3 1 0 0 1 1 1 0 CHY zinc finger zf-RING_UBOX PF13445.1 EPX70733.1 - 0.037 13.7 2.8 0.066 12.9 1.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 EPX70733.1 - 0.037 13.6 4.5 0.14 11.7 3.3 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3133 PF11331.3 EPX70733.1 - 0.073 12.6 3.0 0.18 11.3 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3133) zf-ribbon_3 PF13248.1 EPX70733.1 - 0.11 11.6 3.4 7.6 5.8 3.1 2.4 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4_4 PF15227.1 EPX70733.1 - 0.26 11.2 4.6 0.37 10.7 1.5 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Cytochrome_C7 PF14522.1 EPX70733.1 - 0.46 10.1 4.7 0.78 9.4 3.3 1.3 1 0 0 1 1 1 0 Cytochrome c7 IBR PF01485.16 EPX70733.1 - 2.9 7.8 7.9 5.2 7.0 4.4 2.2 1 1 1 2 2 2 0 IBR domain Miro PF08477.8 EPX70734.1 - 0.014 15.8 0.1 0.02 15.3 0.0 1.4 1 1 0 1 1 1 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EPX70734.1 - 0.14 11.5 0.1 2.7 7.4 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Yos1 PF08571.5 EPX70735.1 - 3.1e-31 107.2 1.9 3.5e-31 107.1 1.3 1.0 1 0 0 1 1 1 1 Yos1-like MIF4G PF02854.14 EPX70736.1 - 6.4e-52 176.0 12.2 4.1e-24 85.1 0.8 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 EPX70736.1 - 2.9e-32 111.7 18.5 2.9e-32 111.7 12.8 2.3 2 1 0 2 2 2 1 Up-frameshift suppressor 2 Alg6_Alg8 PF03155.10 EPX70737.1 - 1.1e-156 522.3 36.8 1.3e-156 522.1 25.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Endonuclease_NS PF01223.18 EPX70738.1 - 7.8e-60 202.0 0.0 9.5e-60 201.7 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease zf-Tim10_DDP PF02953.10 EPX70739.1 - 7.5e-24 82.8 0.3 9.2e-24 82.5 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.3 EPX70739.1 - 0.024 14.4 0.1 0.026 14.3 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) PQ-loop PF04193.9 EPX70740.1 - 1.2e-35 120.8 21.6 1.2e-18 66.4 3.3 2.9 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EPX70740.1 - 0.011 15.5 1.7 0.011 15.5 1.2 2.9 3 2 0 3 3 3 0 Sugar efflux transporter for intercellular exchange NfeD PF01957.13 EPX70740.1 - 0.023 14.8 2.9 6.2 6.9 0.0 3.1 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding COX14 PF14880.1 EPX70740.1 - 0.066 12.8 0.2 0.15 11.6 0.2 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DUF572 PF04502.8 EPX70741.1 - 0.0013 18.0 19.7 0.0016 17.6 13.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) YukD PF08817.5 EPX70741.1 - 0.1 13.1 0.1 0.44 11.1 0.0 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Tox-HDC PF15656.1 EPX70741.1 - 0.12 12.5 1.6 0.47 10.6 0.1 2.2 1 1 2 3 3 3 0 Toxin with a H, D/N and C signature YABBY PF04690.8 EPX70741.1 - 0.79 9.9 11.1 0.048 13.9 1.1 2.2 1 1 1 2 2 2 0 YABBY protein SOBP PF15279.1 EPX70741.1 - 1.8 8.8 13.5 2.3 8.4 9.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein APG6 PF04111.7 EPX70741.1 - 2 7.4 24.5 2.5 7.0 16.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Asp-B-Hydro_N PF05279.6 EPX70741.1 - 3 7.6 19.3 4.1 7.1 13.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Atg14 PF10186.4 EPX70741.1 - 5.6 5.8 19.0 9.5 5.0 13.2 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LMBR1 PF04791.11 EPX70741.1 - 9.3 4.7 7.6 11 4.5 5.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF342 PF03961.8 EPX70741.1 - 9.4 4.5 15.3 13 4.0 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Motile_Sperm PF00635.21 EPX70742.1 - 1.2e-24 86.0 0.0 2.1e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Cut8_C PF08559.5 EPX70743.1 - 5.8e-42 142.8 0.2 8.6e-42 142.3 0.1 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EPX70743.1 - 3.8e-12 45.7 0.5 8.2e-12 44.7 0.3 1.6 1 0 0 1 1 1 1 Cut8 dimerisation domain Pex19 PF04614.7 EPX70744.1 - 1.7e-27 96.6 10.3 2.2e-27 96.2 7.1 1.0 1 0 0 1 1 1 1 Pex19 protein family Imm6 PF14434.1 EPX70744.1 - 0.022 14.4 1.0 0.044 13.5 0.7 1.4 1 0 0 1 1 1 0 Immunity protein Imm6 MAT1 PF06391.8 EPX70744.1 - 0.023 14.3 0.4 0.023 14.3 0.3 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Inos-1-P_synth PF01658.12 EPX70744.1 - 0.25 11.2 2.4 2.8 7.7 1.6 2.1 1 1 0 1 1 1 0 Myo-inositol-1-phosphate synthase Allexi_40kDa PF05549.6 EPX70744.1 - 0.27 10.4 2.9 3.2 6.9 0.2 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF342 PF03961.8 EPX70744.1 - 2.3 6.5 7.6 0.68 8.2 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) RRN3 PF05327.6 EPX70744.1 - 6.1 4.8 9.0 5.6 4.9 5.6 1.4 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sclerostin PF05463.6 EPX70745.1 - 0.005 16.3 0.7 0.0068 15.9 0.5 1.3 1 0 0 1 1 1 1 Sclerostin (SOST) MFS_1 PF07690.11 EPX70746.1 - 2.2e-29 102.3 36.7 2.2e-29 102.3 25.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPX70746.1 - 0.04 12.1 0.2 0.04 12.1 0.2 2.2 2 1 0 3 3 3 0 Fungal trichothecene efflux pump (TRI12) RRM_6 PF14259.1 EPX70747.1 - 1.1e-16 60.5 0.0 8.9e-05 22.3 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX70747.1 - 3.6e-11 42.5 0.0 1.7e-05 24.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX70747.1 - 6.7e-09 35.4 0.0 0.017 14.9 0.0 4.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.7 EPX70748.1 - 1.4e-40 138.7 0.4 1.6e-40 138.4 0.2 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) AFT PF08731.6 EPX70748.1 - 0.023 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 Transcription factor AFT Csm1 PF12539.3 EPX70748.1 - 0.092 13.2 0.9 0.44 11.0 0.1 2.1 2 1 0 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 Snf7 PF03357.16 EPX70749.1 - 3.6e-15 55.7 20.1 3.6e-15 55.7 13.9 1.4 1 1 0 1 1 1 1 Snf7 V_ATPase_I PF01496.14 EPX70749.1 - 5.2 4.7 15.0 58 1.3 10.6 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family SOBP PF15279.1 EPX70749.1 - 6.2 7.1 8.9 8.2 6.7 6.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CS PF04969.11 EPX70750.1 - 1.2e-07 32.1 0.2 1.9e-07 31.4 0.2 1.2 1 0 0 1 1 1 1 CS domain ABC_tran PF00005.22 EPX70751.1 - 8.7e-53 178.3 0.0 2.2e-29 102.5 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPX70751.1 - 6.6e-34 117.5 31.2 6e-17 61.9 10.4 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EPX70751.1 - 3.4e-15 55.8 0.3 0.00011 21.5 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPX70751.1 - 6.6e-09 35.1 0.3 0.00035 20.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EPX70751.1 - 8.8e-09 35.0 0.4 0.0022 17.4 0.0 3.6 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 EPX70751.1 - 8.2e-08 31.4 0.0 0.0078 15.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.12 EPX70751.1 - 5e-07 29.7 2.1 0.0075 16.1 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EPX70751.1 - 3.4e-06 26.7 0.1 0.08 12.4 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_21 PF13304.1 EPX70751.1 - 3.9e-06 27.0 12.6 0.11 12.4 1.5 5.2 4 1 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EPX70751.1 - 7.4e-06 26.4 2.2 0.0019 18.5 0.2 2.6 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EPX70751.1 - 4.7e-05 22.6 0.1 0.062 12.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EPX70751.1 - 6.5e-05 22.5 0.9 0.047 13.1 0.0 2.7 3 0 0 3 3 2 2 AAA-like domain AAA_17 PF13207.1 EPX70751.1 - 0.0001 23.1 0.0 0.34 11.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EPX70751.1 - 0.00012 22.0 0.2 0.37 10.7 0.1 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EPX70751.1 - 0.00018 21.6 0.8 0.8 9.8 0.0 3.4 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EPX70751.1 - 0.00021 20.8 0.0 0.016 14.7 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EPX70751.1 - 0.00048 20.1 0.7 0.099 12.6 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EPX70751.1 - 0.0027 17.5 0.3 0.42 10.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EPX70751.1 - 0.0035 17.6 0.2 3 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EPX70751.1 - 0.0079 15.9 1.5 2.3 7.9 0.1 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EPX70751.1 - 0.009 16.5 0.0 7.1 7.1 0.0 3.2 2 0 0 2 2 2 0 Miro-like protein AIG1 PF04548.11 EPX70751.1 - 0.0099 14.9 2.0 2 7.4 0.0 2.7 3 0 0 3 3 3 1 AIG1 family IstB_IS21 PF01695.12 EPX70751.1 - 0.01 15.2 0.1 1.5 8.1 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein ResIII PF04851.10 EPX70751.1 - 0.014 15.2 0.1 12 5.6 0.0 3.5 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EPX70751.1 - 0.015 15.0 0.2 0.21 11.3 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 EPX70751.1 - 0.015 15.4 0.5 1.8 8.7 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPX70751.1 - 0.02 14.3 0.0 3 7.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Dynamin_N PF00350.18 EPX70751.1 - 0.021 14.6 1.4 0.73 9.6 0.1 2.8 3 0 0 3 3 2 0 Dynamin family Zeta_toxin PF06414.7 EPX70751.1 - 0.021 13.8 0.6 2.5 7.1 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin NB-ARC PF00931.17 EPX70751.1 - 0.024 13.4 0.1 5.9 5.6 0.0 2.8 3 0 0 3 3 2 0 NB-ARC domain NACHT PF05729.7 EPX70751.1 - 0.033 13.8 1.4 1.5 8.4 0.1 2.6 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 EPX70751.1 - 0.041 13.0 0.4 1.3 8.0 0.0 2.5 2 0 0 2 2 2 0 KaiC TrwB_AAD_bind PF10412.4 EPX70751.1 - 0.099 11.2 0.8 5.5 5.4 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 EPX70751.1 - 0.14 11.1 0.1 5.6 5.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Siva PF05458.7 EPX70751.1 - 0.17 11.4 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) AAA_5 PF07728.9 EPX70751.1 - 0.25 11.0 2.1 10 5.8 0.1 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EPX70751.1 - 0.36 9.9 0.7 30 3.6 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Aldedh PF00171.17 EPX70752.1 - 2.1e-184 613.1 0.0 2.4e-184 612.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LCD1 PF09798.4 EPX70753.1 - 1.3e-21 76.3 22.0 1.8e-12 46.0 5.0 4.0 2 1 0 3 3 3 2 DNA damage checkpoint protein Cortex-I_coil PF09304.5 EPX70753.1 - 0.0054 16.7 8.3 0.013 15.5 5.8 1.6 1 0 0 1 1 1 1 Cortexillin I, coiled coil SurA_N PF09312.6 EPX70753.1 - 0.0062 16.3 1.7 0.018 14.9 1.1 1.8 1 0 0 1 1 1 1 SurA N-terminal domain AAA_23 PF13476.1 EPX70753.1 - 1.2 9.4 10.2 3.4 7.9 7.0 1.8 1 0 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.17 EPX70753.1 - 1.5 8.9 12.4 0.25 11.3 5.5 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ras PF00071.17 EPX70754.1 - 4.5e-67 224.4 0.1 6.1e-67 224.0 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX70754.1 - 1.3e-19 70.7 0.0 2.3e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX70754.1 - 1.2e-13 50.6 0.1 1.4e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPX70754.1 - 2.3e-05 23.6 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPX70754.1 - 0.00034 20.1 0.1 0.0012 18.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPX70754.1 - 0.00043 20.2 0.0 0.0008 19.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPX70754.1 - 0.00097 18.3 0.0 0.0038 16.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EPX70754.1 - 0.0074 15.5 0.1 0.0093 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EPX70754.1 - 0.027 14.4 0.1 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.13 EPX70754.1 - 0.029 13.6 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA PF00004.24 EPX70754.1 - 0.037 14.2 0.1 1.5 9.0 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EPX70754.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EPX70754.1 - 0.088 12.9 0.0 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPX70754.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM PF00493.18 EPX70754.1 - 0.11 11.2 0.1 0.31 9.8 0.0 1.6 2 0 0 2 2 2 0 MCM2/3/5 family G-alpha PF00503.15 EPX70754.1 - 0.13 10.8 2.2 7.3 5.1 0.2 2.7 1 1 1 2 2 2 0 G-protein alpha subunit Thr_synth_N PF14821.1 EPX70755.1 - 1.7e-30 104.8 0.0 3.5e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EPX70755.1 - 8.5e-18 64.6 0.0 1.6e-17 63.7 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Bap31 PF05529.7 EPX70757.1 - 3.1e-45 154.0 3.0 3.7e-45 153.7 2.1 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like NPV_P10 PF05531.7 EPX70757.1 - 0.059 13.6 0.9 0.095 12.9 0.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.6 EPX70757.1 - 0.14 11.5 2.7 0.2 11.0 1.9 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 EPX70757.1 - 0.77 9.3 9.1 0.022 14.3 2.0 1.6 2 0 0 2 2 2 0 IncA protein TMF_DNA_bd PF12329.3 EPX70757.1 - 0.83 9.5 13.1 1.1 9.0 9.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Aconitase PF00330.15 EPX70758.1 - 9.4e-185 614.5 0.0 1.1e-184 614.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPX70758.1 - 1.6e-42 144.7 0.0 2.9e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 EPX70759.1 - 3e-05 24.0 1.6 0.029 14.5 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EPX70759.1 - 0.0092 16.2 15.8 0.094 13.0 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPX70759.1 - 0.025 14.9 22.9 0.061 13.6 0.7 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPX70759.1 - 0.31 11.4 20.4 0.44 11.0 0.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPX70759.1 - 0.33 10.9 6.0 0.19 11.6 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Dus PF01207.12 EPX70760.1 - 5.8e-36 123.9 0.0 1.5e-34 119.2 0.0 2.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EPX70760.1 - 3.5 7.4 7.3 18 5.1 1.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Amidohydro_2 PF04909.9 EPX70761.1 - 4.1e-08 33.1 0.1 8.6e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EPX70761.1 - 1.1e-05 25.2 0.1 2.8e-05 23.9 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EPX70761.1 - 0.00012 22.1 0.0 0.00026 21.1 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EPX70761.1 - 0.036 13.8 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Amidohydrolase RRM_1 PF00076.17 EPX70762.1 - 2.2e-28 97.6 0.1 2e-13 49.7 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX70762.1 - 1.2e-20 73.1 0.0 6.1e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX70762.1 - 1.4e-11 44.0 0.0 1.3e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPX70762.1 - 0.0013 18.5 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.3 EPX70762.1 - 0.084 12.6 0.0 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Limkain b1 DbpA PF03880.10 EPX70762.1 - 0.12 12.1 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 DbpA RNA binding domain Ras PF00071.17 EPX70763.1 - 5.9e-51 172.0 0.0 6.9e-51 171.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX70763.1 - 3.6e-16 59.7 0.0 5.8e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX70763.1 - 2e-06 27.1 0.0 3.1e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPX70763.1 - 0.0012 18.0 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EPX70763.1 - 0.014 14.6 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EPX70763.1 - 0.027 13.9 0.0 2.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EPX70763.1 - 0.09 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase NST1 PF13945.1 EPX70764.1 - 3.2e-63 213.2 11.6 3.2e-63 213.2 8.1 4.5 3 1 2 5 5 5 2 Salt tolerance down-regulator DUF217 PF02697.9 EPX70765.1 - 0.059 13.6 0.2 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized ACR, COG1753 TBP PF00352.16 EPX70766.1 - 4e-68 224.8 0.1 6.4e-35 118.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EPX70766.1 - 0.0013 18.7 0.0 0.53 10.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) tRNA-synt_1e PF01406.14 EPX70767.1 - 4.3e-142 472.6 0.0 8.7e-142 471.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EPX70767.1 - 1.3e-10 40.4 0.8 5.8e-06 25.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EPX70767.1 - 8.4e-06 24.0 0.4 0.00061 17.9 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 EPX70767.1 - 0.00029 19.6 0.0 0.02 13.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (K) Nnf1 PF03980.9 EPX70768.1 - 1.2e-26 92.8 6.2 1.2e-26 92.8 4.3 1.7 2 0 0 2 2 2 1 Nnf1 Leu_zip PF15294.1 EPX70768.1 - 0.0021 17.2 11.3 0.0026 16.9 7.9 1.2 1 0 0 1 1 1 1 Leucine zipper XPG_I_2 PF12813.2 EPX70768.1 - 0.13 11.7 2.4 0.16 11.4 1.7 1.1 1 0 0 1 1 1 0 XPG domain containing TnpV PF14198.1 EPX70768.1 - 0.42 10.5 7.8 0.19 11.6 2.3 2.2 1 1 1 2 2 2 0 Transposon-encoded protein TnpV DUF4163 PF13739.1 EPX70768.1 - 2.7 8.8 5.6 19 6.0 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) PMSR PF01625.16 EPX70769.1 - 8.3e-58 194.6 1.0 9.7e-58 194.4 0.7 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Cnd3 PF12719.2 EPX70769.1 - 0.063 12.2 0.0 0.079 11.9 0.0 1.1 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Uso1_p115_head PF04869.9 EPX70770.1 - 3.2e-64 216.6 5.1 9.6e-64 215.0 3.5 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region IncA PF04156.9 EPX70770.1 - 0.00016 21.3 94.6 0.15 11.6 17.8 6.1 1 1 5 6 6 6 4 IncA protein WEMBL PF05701.6 EPX70770.1 - 0.0059 15.1 79.7 0.26 9.6 44.8 2.2 1 1 1 2 2 2 2 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 EPX70770.1 - 0.12 11.5 38.9 0.057 12.6 5.8 5.0 2 1 3 5 5 5 0 Reovirus sigma C capsid protein ERM PF00769.14 EPX70770.1 - 2 7.9 81.1 0.83 9.1 18.2 4.3 1 1 2 4 4 4 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.4 EPX70770.1 - 3.2 7.6 104.5 2 8.2 8.2 5.5 2 2 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EPX70770.1 - 5.6 6.3 75.9 0.56 9.6 19.1 4.4 1 1 1 3 3 3 0 Intermediate filament protein DUF869 PF05911.6 EPX70770.1 - 5.7 5.0 82.9 0.038 12.2 36.9 3.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) APG6 PF04111.7 EPX70770.1 - 7.7 5.4 92.0 0.38 9.7 9.4 4.6 1 1 3 4 4 4 0 Autophagy protein Apg6 PRP3 PF08572.5 EPX70771.1 - 1.1e-65 221.1 10.5 1.8e-65 220.4 7.3 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EPX70771.1 - 5.4e-37 126.3 0.1 5.4e-37 126.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) WD40 PF00400.27 EPX70772.1 - 3.3e-49 163.0 21.1 5.9e-09 35.4 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EPX70772.1 - 3.4e-12 45.8 0.8 8.3e-12 44.6 0.5 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EPX70772.1 - 6.9e-08 31.0 4.5 0.0034 15.5 0.0 4.1 3 1 1 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.28 EPX70772.1 - 2.2e-07 30.3 0.3 5.4e-07 29.0 0.2 1.8 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EPX70772.1 - 0.01 15.2 0.1 1.3 8.4 0.0 2.8 2 1 0 2 2 2 0 PQQ-like domain Nucleoporin_N PF08801.6 EPX70772.1 - 0.029 13.1 7.6 1.8 7.2 0.2 4.2 1 1 2 3 3 3 0 Nup133 N terminal like BBS2_Mid PF14783.1 EPX70772.1 - 0.053 13.2 0.1 0.74 9.6 0.0 3.0 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EPX70772.1 - 0.069 13.4 1.5 28 5.1 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain ABC_tran PF00005.22 EPX70773.1 - 1.1e-47 161.7 0.5 1.8e-27 96.2 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPX70773.1 - 5.5e-42 144.0 32.9 3.2e-21 75.9 8.0 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EPX70773.1 - 3.3e-14 52.6 6.6 0.00048 19.4 2.3 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPX70773.1 - 5.3e-12 46.2 12.1 7.2e-05 22.8 0.5 5.0 4 1 0 4 4 3 2 AAA domain AAA_23 PF13476.1 EPX70773.1 - 2.7e-08 34.3 0.1 4.9e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPX70773.1 - 1.4e-06 27.7 0.5 0.058 12.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPX70773.1 - 1.9e-06 27.1 0.1 0.0015 17.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EPX70773.1 - 9.7e-06 25.1 0.0 0.02 14.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 EPX70773.1 - 1.8e-05 23.7 2.9 0.04 12.8 0.1 3.0 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_25 PF13481.1 EPX70773.1 - 2.4e-05 23.8 0.1 0.023 14.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EPX70773.1 - 3.1e-05 24.0 0.5 0.054 13.4 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EPX70773.1 - 7.8e-05 23.4 0.0 0.83 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EPX70773.1 - 0.00011 21.9 1.3 0.14 11.8 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EPX70773.1 - 0.00017 21.7 0.4 0.049 13.8 0.0 3.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EPX70773.1 - 0.0003 21.0 0.0 1.1 9.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EPX70773.1 - 0.00045 20.7 1.3 0.22 12.0 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein AAA_10 PF12846.2 EPX70773.1 - 0.00047 19.6 1.3 0.45 9.9 0.0 2.7 2 1 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 EPX70773.1 - 0.00079 19.5 4.6 0.45 10.6 0.1 3.7 2 2 0 2 2 2 1 AAA domain DUF87 PF01935.12 EPX70773.1 - 0.0011 18.7 3.2 0.13 12.0 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 Arch_ATPase PF01637.13 EPX70773.1 - 0.0013 18.4 0.2 0.017 14.7 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase MMR_HSR1 PF01926.18 EPX70773.1 - 0.0014 18.6 4.3 0.8 9.6 0.4 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EPX70773.1 - 0.0016 17.6 0.5 0.11 11.6 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.1 EPX70773.1 - 0.018 14.9 3.4 0.4 10.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EPX70773.1 - 0.019 14.8 0.1 18 5.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 EPX70773.1 - 0.025 14.1 0.1 6 6.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EPX70773.1 - 0.028 14.1 0.2 0.31 10.8 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Dynamin_N PF00350.18 EPX70773.1 - 0.033 14.0 2.9 0.28 10.9 0.4 2.6 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 EPX70773.1 - 0.034 13.8 1.7 1.7 8.2 0.1 2.7 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.12 EPX70773.1 - 0.041 13.3 0.8 5.9 6.2 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_5 PF07728.9 EPX70773.1 - 0.054 13.2 2.4 16 5.1 0.0 3.7 3 1 1 4 4 3 0 AAA domain (dynein-related subfamily) ResIII PF04851.10 EPX70773.1 - 0.056 13.2 0.4 17 5.1 0.0 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF815 PF05673.8 EPX70773.1 - 0.081 11.8 0.2 2.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EPX70773.1 - 0.12 11.2 0.1 4.5 6.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DEAD PF00270.24 EPX70773.1 - 0.13 11.7 0.7 12 5.3 0.0 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase PduV-EutP PF10662.4 EPX70773.1 - 0.15 11.5 1.0 4.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.11 EPX70773.1 - 0.16 11.1 0.1 4.8 6.3 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein ATP_bind_1 PF03029.12 EPX70773.1 - 0.17 11.4 1.4 3.9 6.9 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 EPX70773.1 - 0.17 11.3 0.1 20 4.5 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Guanylate_kin PF00625.16 EPX70773.1 - 0.18 11.2 0.4 0.57 9.5 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase cobW PF02492.14 EPX70773.1 - 0.2 11.1 4.1 1.4 8.3 0.5 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EPX70773.1 - 0.31 10.6 0.1 6.2 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 EPX70773.1 - 0.52 9.5 4.6 15 4.7 0.0 3.2 3 0 0 3 3 3 0 Poxvirus A32 protein Translin PF01997.11 EPX70774.1 - 1.9e-37 128.8 2.8 2.2e-37 128.6 2.0 1.0 1 0 0 1 1 1 1 Translin family MCC-bdg_PDZ PF10506.4 EPX70774.1 - 0.0049 16.6 1.6 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 PDZ domain of MCC-2 bdg protein for Usher syndrome Filament PF00038.16 EPX70774.1 - 0.1 12.0 3.1 0.055 12.9 0.9 1.5 2 0 0 2 2 2 0 Intermediate filament protein KTI12 PF08433.5 EPX70775.1 - 7.9e-95 317.1 0.0 8.9e-95 316.9 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EPX70775.1 - 5.3e-06 27.2 0.0 8.7e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPX70775.1 - 0.00013 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPX70775.1 - 0.00029 21.1 0.0 0.00045 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPX70775.1 - 0.038 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EPX70775.1 - 0.068 12.8 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Sec7 PF01369.15 EPX70776.1 - 1.8e-67 226.6 0.6 5.6e-67 225.0 0.4 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EPX70776.1 - 5e-46 156.2 4.6 5e-46 156.2 3.2 3.1 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EPX70776.1 - 7.4e-29 99.1 14.4 1.6e-27 94.8 0.2 6.3 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) La PF05383.12 EPX70777.1 - 5.6e-21 74.1 0.0 9.5e-21 73.3 0.0 1.4 1 0 0 1 1 1 1 La domain Got1 PF04178.7 EPX70778.1 - 1.9e-24 86.0 18.6 2.5e-24 85.6 12.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family SID-1_RNA_chan PF13965.1 EPX70778.1 - 0.02 13.1 1.7 0.035 12.2 1.2 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Glycophorin_A PF01102.13 EPX70778.1 - 0.4 10.4 1.8 0.69 9.6 1.3 1.4 1 0 0 1 1 1 0 Glycophorin A DUF3671 PF12420.3 EPX70778.1 - 2.1 8.3 7.6 3 7.8 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF485 PF04341.7 EPX70778.1 - 9.3 6.0 11.7 0.34 10.6 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF485 Alpha-amylase PF00128.19 EPX70779.1 - 2.8e-27 95.9 0.2 2.8e-24 86.0 0.1 3.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EPX70779.1 - 8.8e-14 51.5 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EPX70779.1 - 3.4e-07 29.8 0.0 8.9e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 EPX70779.1 - 0.0063 17.0 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial Ig-like domain Alpha-amylase PF00128.19 EPX70780.1 - 1.4e-63 215.1 2.8 1.4e-63 215.1 1.9 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EPX70780.1 - 6.2e-08 32.6 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF187 PF02638.10 EPX70780.1 - 0.0023 16.8 0.1 0.0043 15.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 Sec7_N PF12783.2 EPX70781.1 - 4.5e-30 104.2 4.3 4.5e-30 104.2 3.0 5.0 5 1 1 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EPX70781.1 - 6.2e-05 22.4 1.2 0.045 13.2 0.2 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1981) Inhibitor_I78 PF11720.3 EPX70782.1 - 1.3e-09 37.6 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EPX70782.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.5 1 1 1 2 2 2 0 Potato inhibitor I family adh_short PF00106.20 EPX70784.1 - 2.1e-20 73.2 0.2 2.9e-20 72.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPX70784.1 - 9.1e-15 55.0 0.6 1.1e-14 54.8 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPX70784.1 - 8.6e-06 25.5 0.2 1.3e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPX70784.1 - 0.00022 21.2 0.3 0.00049 20.1 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 EPX70784.1 - 0.0033 16.6 0.2 0.061 12.4 0.1 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EPX70784.1 - 0.0074 15.7 0.6 0.014 14.7 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPX70784.1 - 0.028 13.6 0.3 0.042 13.0 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family PAE PF03283.8 EPX70784.1 - 0.036 12.6 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Glyco_hydro_81 PF03639.8 EPX70785.1 - 1.1e-242 807.0 24.3 1.3e-242 806.8 16.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Cas_APE2256 PF09651.5 EPX70785.1 - 0.0054 16.4 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_APE2256) Actin PF00022.14 EPX70786.1 - 1.7e-130 434.9 0.0 2e-130 434.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPX70786.1 - 5.1e-08 31.8 0.0 0.00016 20.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.3 EPX70786.1 - 0.11 11.3 0.1 0.81 8.4 0.0 2.0 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Proteasome PF00227.21 EPX70788.1 - 5.2e-47 159.6 0.0 6.5e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EPX70788.1 - 1.8e-13 49.4 0.3 4.1e-13 48.3 0.2 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal NAD_Gly3P_dh_N PF01210.18 EPX70790.1 - 6.7e-53 178.6 0.0 1.8e-52 177.2 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EPX70790.1 - 1.5e-51 174.0 0.1 3.2e-51 172.9 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EPX70790.1 - 0.0087 16.4 0.1 3.5 8.1 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent RabGAP-TBC PF00566.13 EPX70791.1 - 5.3e-27 94.7 5.4 5.3e-27 94.7 3.7 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain AAA PF00004.24 EPX70792.1 - 5.8e-15 55.6 0.0 1.2e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EPX70792.1 - 2e-14 53.3 0.1 4.9e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPX70792.1 - 1.3e-13 50.9 0.0 8.2e-13 48.3 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EPX70792.1 - 4.4e-09 35.5 0.1 0.0016 17.2 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EPX70792.1 - 6.1e-05 23.1 0.0 0.004 17.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPX70792.1 - 9.4e-05 22.0 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EPX70792.1 - 0.00016 21.3 0.0 0.00031 20.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPX70792.1 - 0.00017 20.7 0.0 0.00037 19.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 EPX70792.1 - 0.00018 21.0 0.0 0.00035 20.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF815 PF05673.8 EPX70792.1 - 0.00025 20.0 0.0 0.00075 18.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EPX70792.1 - 0.00056 19.9 0.2 0.012 15.6 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 EPX70792.1 - 0.0038 16.8 0.6 0.023 14.2 0.2 2.2 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EPX70792.1 - 0.005 16.0 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EPX70792.1 - 0.013 15.0 0.0 0.038 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EPX70792.1 - 0.017 14.5 0.1 0.045 13.2 0.0 1.6 1 1 0 1 1 1 0 FtsK/SpoIIIE family DUF2075 PF09848.4 EPX70792.1 - 0.018 14.0 0.0 0.05 12.5 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EPX70792.1 - 0.032 13.9 0.0 0.08 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPX70792.1 - 0.033 13.8 0.0 0.087 12.4 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EPX70792.1 - 0.038 13.9 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EPX70792.1 - 0.039 13.3 0.0 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EPX70792.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EPX70792.1 - 0.075 12.4 0.2 0.8 9.0 0.1 2.7 1 1 0 1 1 1 0 AAA-like domain TrwB_AAD_bind PF10412.4 EPX70792.1 - 0.11 11.1 0.0 0.19 10.2 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SNF2_N PF00176.18 EPX70792.1 - 0.12 11.1 0.1 3.1 6.5 0.0 2.4 2 1 0 3 3 3 0 SNF2 family N-terminal domain AAA_17 PF13207.1 EPX70792.1 - 0.15 12.9 0.0 0.31 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain PWWP PF00855.12 EPX70793.1 - 2.9e-08 33.7 0.2 1.7e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 PWWP domain NAM-associated PF14303.1 EPX70793.1 - 0.033 14.5 10.7 0.73 10.1 0.5 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain SF3b1 PF08920.5 EPX70794.1 - 1.8e-17 63.7 4.9 1.1e-16 61.2 3.4 2.4 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EPX70794.1 - 5.3e-17 61.8 7.3 0.00058 20.0 0.0 7.8 7 1 1 8 8 8 5 HEAT repeats HEAT PF02985.17 EPX70794.1 - 1.1e-15 56.2 5.3 0.035 14.1 0.0 10.3 10 0 0 10 10 9 3 HEAT repeat HEAT_EZ PF13513.1 EPX70794.1 - 3.2e-14 52.9 4.2 0.14 12.7 0.0 8.1 7 2 1 8 8 8 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPX70794.1 - 7.5e-07 29.4 0.8 1 9.8 0.0 5.7 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.7 EPX70794.1 - 8.4e-05 22.0 0.5 0.35 10.2 0.0 4.8 5 0 0 5 5 5 1 NUC173 domain Adaptin_N PF01602.15 EPX70794.1 - 0.0004 18.8 0.5 0.018 13.3 0.1 3.2 1 1 0 1 1 1 1 Adaptin N terminal region UNC45-central PF11701.3 EPX70794.1 - 0.0013 18.3 0.1 0.05 13.2 0.0 3.3 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central DUF3385 PF11865.3 EPX70794.1 - 0.0015 18.4 2.1 0.32 10.9 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Arm PF00514.18 EPX70794.1 - 0.0015 18.2 3.1 7.4 6.5 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EPX70794.1 - 0.0018 17.6 0.6 1.5 8.1 0.0 3.5 4 0 0 4 4 4 1 CLASP N terminal Dopey_N PF04118.9 EPX70794.1 - 0.0031 16.3 1.4 0.26 10.0 0.0 3.6 3 1 0 3 3 3 1 Dopey, N-terminal Cnd1 PF12717.2 EPX70794.1 - 0.0041 16.9 2.3 19 5.0 0.0 4.8 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 CRM1_C PF08767.6 EPX70794.1 - 0.018 14.0 0.1 0.057 12.3 0.0 1.8 1 0 0 1 1 1 0 CRM1 C terminal DUF4533 PF15047.1 EPX70794.1 - 0.1 12.0 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) Nramp PF01566.13 EPX70795.1 - 8.6e-92 307.6 19.9 1.3e-91 307.1 13.8 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein ORC2 PF04084.9 EPX70795.1 - 0.12 11.2 0.2 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 Ribophorin_I PF04597.9 EPX70796.1 - 1.2e-108 363.4 8.5 1.3e-108 363.3 5.9 1.0 1 0 0 1 1 1 1 Ribophorin I DUF2808 PF10989.3 EPX70796.1 - 0.0031 17.1 0.2 0.053 13.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2808) FKBP_C PF00254.23 EPX70797.1 - 7.2e-27 93.2 0.0 2.6e-26 91.4 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase RR_TM4-6 PF06459.7 EPX70797.1 - 0.0075 16.1 17.1 0.47 10.2 10.1 2.3 2 0 0 2 2 2 2 Ryanodine Receptor TM 4-6 Dynamin_N PF00350.18 EPX70797.1 - 0.39 10.5 5.4 1 9.1 2.8 2.0 2 0 0 2 2 2 0 Dynamin family Hid1 PF12722.2 EPX70797.1 - 0.52 7.9 6.8 0.59 7.7 4.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 EPX70797.1 - 0.67 8.3 2.2 0.75 8.1 1.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.1 EPX70797.1 - 2.2 6.5 5.5 2.7 6.2 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF2413 PF10310.4 EPX70797.1 - 3.1 6.5 17.4 4.8 5.8 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Herpes_DNAp_acc PF04929.7 EPX70797.1 - 4.1 6.2 10.1 5.8 5.7 7.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Neur_chan_memb PF02932.11 EPX70797.1 - 6 6.6 6.4 10 5.9 4.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2951 PF11166.3 EPX70797.1 - 8.5 6.3 10.7 9.1 6.2 5.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Ycf1 PF05758.7 EPX70797.1 - 8.5 3.9 10.4 11 3.6 7.2 1.1 1 0 0 1 1 1 0 Ycf1 Aminotran_3 PF00202.16 EPX70798.1 - 6e-13 48.3 0.0 1.1e-09 37.6 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-III Nuf2 PF03800.9 EPX70799.1 - 3.8e-42 143.7 2.8 3.8e-42 143.7 1.9 2.7 2 1 0 2 2 2 1 Nuf2 family DUF2265 PF10023.4 EPX70799.1 - 8 5.4 19.9 2.8 7.0 2.2 2.3 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) Peptidase_C12 PF01088.16 EPX70800.1 - 4.6e-48 163.2 0.0 5.2e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Rtf2 PF04641.7 EPX70800.1 - 0.022 13.9 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Methyltransf_12 PF08242.7 EPX70800.1 - 0.036 14.5 0.0 0.061 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Nop25 PF09805.4 EPX70800.1 - 0.041 13.9 0.8 0.056 13.5 0.6 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Tropomyosin_1 PF12718.2 EPX70801.1 - 1.3e-37 128.8 33.5 1.6e-37 128.5 23.2 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EPX70801.1 - 6.3e-13 48.3 37.1 8.5e-07 28.3 5.0 3.0 1 1 2 3 3 3 3 Tropomyosin GAS PF13851.1 EPX70801.1 - 1.8e-05 24.0 29.1 0.0016 17.7 13.8 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 EPX70801.1 - 0.0017 18.2 0.4 0.0017 18.2 0.3 4.4 2 2 2 4 4 4 1 bZIP transcription factor FlaC_arch PF05377.6 EPX70801.1 - 0.0034 17.2 15.8 0.25 11.2 2.6 3.9 2 2 1 4 4 4 2 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 EPX70801.1 - 0.0044 16.8 6.4 0.0044 16.8 4.4 2.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.3 EPX70801.1 - 0.0082 15.4 20.3 0.046 12.9 3.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) NPV_P10 PF05531.7 EPX70801.1 - 0.0088 16.2 6.3 0.13 12.5 0.1 3.2 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein PilJ PF13675.1 EPX70801.1 - 0.0097 16.2 10.2 0.19 12.0 0.5 2.3 1 1 1 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4164 PF13747.1 EPX70801.1 - 0.012 15.7 9.9 0.012 15.7 6.8 2.9 1 1 2 3 3 2 0 Domain of unknown function (DUF4164) Laminin_II PF06009.7 EPX70801.1 - 0.013 15.2 5.0 0.013 15.2 3.5 2.6 1 1 1 2 2 2 0 Laminin Domain II DUF4200 PF13863.1 EPX70801.1 - 0.014 15.3 12.0 0.014 15.3 8.3 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 EPX70801.1 - 0.02 14.6 3.9 0.02 14.6 2.7 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Filament PF00038.16 EPX70801.1 - 0.023 14.1 27.9 0.71 9.2 6.6 2.6 1 1 0 2 2 2 0 Intermediate filament protein IncA PF04156.9 EPX70801.1 - 0.024 14.2 33.6 0.38 10.3 10.2 2.0 1 1 1 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 EPX70801.1 - 0.031 13.4 3.2 0.38 9.9 0.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EPX70801.1 - 0.033 14.0 34.3 0.49 10.2 6.7 3.9 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding WEMBL PF05701.6 EPX70801.1 - 0.036 12.5 30.8 0.046 12.1 21.4 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light BLOC1_2 PF10046.4 EPX70801.1 - 0.04 14.0 15.4 0.69 10.0 4.9 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_I PF06008.9 EPX70801.1 - 0.049 12.9 22.7 0.036 13.3 4.0 2.5 1 1 2 3 3 3 0 Laminin Domain I TBPIP PF07106.8 EPX70801.1 - 0.06 12.8 26.4 0.32 10.5 6.6 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_13 PF13166.1 EPX70801.1 - 0.064 11.7 20.8 0.033 12.6 8.9 1.8 1 1 1 2 2 2 0 AAA domain Adeno_PIX PF03955.9 EPX70801.1 - 0.067 13.7 12.6 0.86 10.1 2.4 2.7 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) Prefoldin PF02996.12 EPX70801.1 - 0.086 12.4 0.7 0.086 12.4 0.5 4.0 2 2 2 4 4 4 0 Prefoldin subunit ATG16 PF08614.6 EPX70801.1 - 0.088 12.6 29.2 0.15 11.9 8.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.7 EPX70801.1 - 0.091 12.5 1.3 0.58 9.9 0.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Taxilin PF09728.4 EPX70801.1 - 0.13 11.3 25.6 0.3 10.1 7.2 2.2 1 1 1 2 2 2 0 Myosin-like coiled-coil protein APG6 PF04111.7 EPX70801.1 - 0.14 11.1 33.1 0.063 12.3 8.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 MamL-1 PF09596.5 EPX70801.1 - 0.15 11.9 0.1 0.15 11.9 0.1 3.0 3 1 1 4 4 3 0 MamL-1 domain DUF3584 PF12128.3 EPX70801.1 - 0.15 9.3 28.7 0.27 8.4 19.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.3 EPX70801.1 - 0.17 11.7 25.1 1.7 8.5 4.5 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding AAA_27 PF13514.1 EPX70801.1 - 0.22 9.1 26.5 1.6 6.3 18.4 2.4 1 1 0 1 1 1 0 AAA domain DUF4463 PF14703.1 EPX70801.1 - 0.22 12.0 0.3 0.22 12.0 0.2 3.6 1 1 1 2 2 1 0 Domain of unknown function (DUF4463) WXG100 PF06013.7 EPX70801.1 - 0.23 11.5 11.1 5.6 7.0 0.7 3.7 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DUF641 PF04859.7 EPX70801.1 - 0.23 11.2 18.9 0.47 10.2 4.3 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) EzrA PF06160.7 EPX70801.1 - 0.23 9.5 22.8 2.2 6.3 5.5 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Nup54 PF13874.1 EPX70801.1 - 0.26 10.9 20.6 0.44 10.1 3.1 2.4 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Spectrin PF00435.16 EPX70801.1 - 0.34 11.2 23.5 1.3 9.3 8.5 2.8 1 1 1 2 2 2 0 Spectrin repeat KLRAQ PF10205.4 EPX70801.1 - 0.34 10.9 21.1 2.5 8.1 5.4 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein MAD PF05557.8 EPX70801.1 - 0.52 8.3 26.0 0.055 11.5 7.9 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein CCDC155 PF14662.1 EPX70801.1 - 0.54 9.8 30.2 0.43 10.1 18.1 2.1 1 1 1 2 2 1 0 Coiled-coil region of CCDC155 Streptin-Immun PF11083.3 EPX70801.1 - 0.55 10.2 15.3 0.87 9.6 1.8 3.3 1 1 3 4 4 4 0 Lantibiotic streptin immunity protein DUF342 PF03961.8 EPX70801.1 - 0.56 8.5 24.8 0.11 10.8 5.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) ORF6C PF10552.4 EPX70801.1 - 0.56 9.9 17.2 0.39 10.4 0.6 3.8 1 1 1 3 3 3 0 ORF6C domain Uds1 PF15456.1 EPX70801.1 - 0.56 10.2 27.3 0.14 12.1 6.2 2.4 1 1 1 2 2 2 0 Up-regulated During Septation Ax_dynein_light PF10211.4 EPX70801.1 - 0.58 9.9 25.6 1.2 8.9 2.7 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain TPR_MLP1_2 PF07926.7 EPX70801.1 - 0.58 9.8 30.8 0.34 10.6 8.8 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein MIF4G_like_2 PF09090.6 EPX70801.1 - 0.59 9.3 13.1 0.48 9.6 8.0 1.6 1 1 0 1 1 1 0 MIF4G like ERM PF00769.14 EPX70801.1 - 0.62 9.5 37.1 0.11 11.9 16.0 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Spc7 PF08317.6 EPX70801.1 - 0.64 8.6 26.1 1.6 7.2 10.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 EPX70801.1 - 0.65 9.7 32.6 0.31 10.7 3.3 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 EPX70801.1 - 0.72 8.7 24.9 0.2 10.5 12.2 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF869 PF05911.6 EPX70801.1 - 0.85 7.7 26.6 4.7 5.3 18.5 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Occludin_ELL PF07303.8 EPX70801.1 - 1.5 9.5 17.5 27 5.5 2.5 3.5 1 1 1 2 2 2 0 Occludin homology domain Seryl_tRNA_N PF02403.17 EPX70801.1 - 1.6 8.8 28.1 3.4 7.7 1.3 3.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Rootletin PF15035.1 EPX70801.1 - 2 8.3 26.4 15 5.4 18.3 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF948 PF06103.6 EPX70801.1 - 2.3 8.1 10.3 0.67 9.8 1.0 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) FliD_C PF07195.7 EPX70801.1 - 2.4 7.3 11.2 5 6.3 1.1 2.6 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus CALCOCO1 PF07888.6 EPX70801.1 - 2.6 6.2 25.8 4.9 5.3 17.9 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spore_III_AB PF09548.5 EPX70801.1 - 2.7 7.6 11.3 6.5 6.4 1.4 2.5 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) IFT57 PF10498.4 EPX70801.1 - 3.3 6.3 22.2 0.73 8.5 5.7 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF812 PF05667.6 EPX70801.1 - 3.5 6.0 24.9 8.4 4.7 6.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Vfa1 PF08432.5 EPX70801.1 - 3.5 7.5 21.3 4.7 7.1 13.0 1.9 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Prefoldin_2 PF01920.15 EPX70801.1 - 3.8 7.3 32.8 1.6 8.4 1.8 4.3 1 1 3 4 4 4 0 Prefoldin subunit Cep57_CLD_2 PF14197.1 EPX70801.1 - 4.1 7.4 30.7 0.52 10.2 4.4 3.9 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 Synaptonemal_3 PF15191.1 EPX70801.1 - 4.1 7.1 12.4 5 6.9 0.9 3.2 1 1 2 3 3 3 0 Synaptonemal complex central element protein 3 Phage_GP20 PF06810.6 EPX70801.1 - 5.5 6.4 25.1 7.5 5.9 7.1 3.0 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF3829 PF12889.2 EPX70801.1 - 5.9 5.9 15.7 6.5 5.8 10.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) DUF2009 PF09418.5 EPX70801.1 - 6 5.5 9.5 6.1 5.4 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2009) Mnd1 PF03962.10 EPX70801.1 - 6.1 6.4 29.1 1.9 8.1 9.6 2.4 1 1 2 3 3 3 0 Mnd1 family Sec34 PF04136.10 EPX70801.1 - 6.4 6.4 11.9 1.7 8.3 0.2 2.4 1 1 1 2 2 2 0 Sec34-like family DUF4140 PF13600.1 EPX70801.1 - 6.5 7.2 25.1 0.97 9.9 1.4 3.7 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) Fib_alpha PF08702.5 EPX70801.1 - 6.8 6.8 14.4 4.9 7.2 3.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.9 EPX70801.1 - 7 6.2 27.7 5.4 6.5 5.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CENP-Q PF13094.1 EPX70801.1 - 7.4 6.5 31.3 52 3.8 21.7 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FUSC PF04632.7 EPX70801.1 - 7.4 4.8 7.8 9.1 4.5 5.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.14 EPX70801.1 - 8.4 4.1 22.1 45 1.6 15.3 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family rRNA_proc-arch PF13234.1 EPX70801.1 - 8.8 5.3 16.1 11 5.0 1.2 3.1 1 1 2 3 3 3 0 rRNA-processing arch domain bZIP_Maf PF03131.12 EPX70801.1 - 8.9 6.6 20.2 4 7.8 1.8 3.3 1 1 2 3 3 3 0 bZIP Maf transcription factor FemAB PF02388.11 EPX70801.1 - 9.2 4.8 16.7 1.3 7.6 2.7 2.3 1 1 1 2 2 2 0 FemAB family DUF1720 PF08226.6 EPX70802.1 - 6.9e-31 106.1 385.7 8.1e-08 32.2 16.6 18.2 3 2 4 7 7 4 3 Domain of unknown function (DUF1720) EF-hand_4 PF12763.2 EPX70802.1 - 6.3e-26 90.1 0.0 2.8e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EPX70802.1 - 7.8e-06 25.3 0.2 1.6e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 EPX70802.1 - 0.0011 19.0 0.0 0.0038 17.3 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair Prefoldin_2 PF01920.15 EPX70802.1 - 0.031 14.0 11.2 0.014 15.1 2.8 2.4 2 0 0 2 2 2 0 Prefoldin subunit EF-hand_6 PF13405.1 EPX70802.1 - 0.035 13.9 0.2 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain AAA_13 PF13166.1 EPX70802.1 - 0.046 12.1 10.9 0.079 11.4 7.5 1.3 1 0 0 1 1 1 0 AAA domain EF-hand_1 PF00036.27 EPX70802.1 - 0.14 11.5 0.0 79 2.9 0.0 3.2 3 0 0 3 3 3 0 EF hand Spc7 PF08317.6 EPX70802.1 - 0.19 10.3 13.8 0.33 9.5 9.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 EPX70802.1 - 0.3 10.8 13.7 0.18 11.6 5.3 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 EPX70802.1 - 0.79 9.6 11.4 3 7.8 1.5 3.3 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Prominin PF05478.6 EPX70802.1 - 1.9 5.8 7.9 2.9 5.2 5.5 1.2 1 0 0 1 1 1 0 Prominin Reo_sigmaC PF04582.7 EPX70802.1 - 3.9 6.5 9.2 7.2 5.6 6.4 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TBPIP PF07106.8 EPX70802.1 - 5.8 6.4 18.0 4.3 6.8 3.9 3.2 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) eIF2A PF08662.6 EPX70803.1 - 3.1e-42 144.4 3.4 2.4e-40 138.3 0.6 3.1 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EPX70803.1 - 0.00042 19.8 0.1 0.0012 18.4 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX70803.1 - 0.002 18.0 0.0 0.006 16.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-bind_3 PF12776.2 EPX70803.1 - 0.044 14.4 4.0 5.4 7.7 0.1 3.8 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain RRM_5 PF13893.1 EPX70803.1 - 0.085 12.7 0.1 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.18 EPX70804.1 - 1.2e-108 362.8 0.7 1.2e-108 362.8 0.5 3.1 3 0 0 3 3 3 1 Kinesin motor domain Ribosomal_S28e PF01200.13 EPX70805.1 - 3.4e-34 116.4 2.0 3.6e-34 116.3 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.13 EPX70806.1 - 5.2e-56 188.7 0.1 8.9e-56 187.9 0.1 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EPX70806.1 - 1.5e-26 92.1 0.3 2.8e-26 91.2 0.2 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EPX70806.1 - 0.043 13.3 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like Red1 PF07964.6 EPX70807.1 - 2.5e-15 55.7 37.7 4.7e-13 48.1 19.5 2.4 1 1 0 2 2 2 2 Rec10 / Red1 bZIP_2 PF07716.10 EPX70808.1 - 6.4e-11 41.9 12.6 1.3e-10 40.9 8.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EPX70808.1 - 1e-05 25.3 9.2 2.4e-05 24.2 6.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 EPX70808.1 - 0.0006 19.6 1.5 0.0013 18.5 1.0 1.6 1 0 0 1 1 1 1 Haemolysin XhlA bZIP_Maf PF03131.12 EPX70808.1 - 0.021 15.1 2.2 0.047 13.9 1.5 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor TSC22 PF01166.13 EPX70808.1 - 0.051 13.5 0.1 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4094 PF13334.1 EPX70808.1 - 0.17 12.3 1.1 0.47 10.8 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF4551 PF15087.1 EPX70808.1 - 4 5.6 9.1 0.95 7.7 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4551) Ydc2-catalyt PF09159.5 EPX70809.1 - 2.6e-34 118.9 1.3 8.3e-31 107.4 0.9 2.2 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EPX70809.1 - 6.2e-06 26.1 0.2 0.011 15.6 0.0 3.1 2 1 0 2 2 2 2 Poxvirus A22 protein SAP PF02037.22 EPX70809.1 - 0.00014 21.2 0.8 0.00038 19.8 0.5 1.7 1 0 0 1 1 1 1 SAP domain Terminase_6 PF03237.10 EPX70809.1 - 0.02 13.6 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family OrfB_IS605 PF01385.14 EPX70809.1 - 0.08 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Probable transposase RRM_1 PF00076.17 EPX70810.1 - 4.8e-18 64.5 0.0 9.4e-18 63.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX70810.1 - 1.2e-14 53.9 0.0 2.4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX70810.1 - 1.1e-09 38.0 0.0 2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EPX70810.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PMBR PF09373.5 EPX70810.1 - 0.13 12.2 3.4 36 4.5 0.0 3.7 3 0 0 3 3 3 0 Pseudomurein-binding repeat MS_channel PF00924.13 EPX70811.1 - 1.4e-34 119.2 1.0 3e-34 118.1 0.7 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.1 EPX70811.1 - 0.073 12.9 0.1 0.23 11.4 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain Ribosomal_S8e PF01201.17 EPX70812.1 - 6.2e-51 172.0 1.2 7.1e-51 171.8 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EPX70812.1 - 0.029 14.6 0.2 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Small acidic protein family UBX PF00789.15 EPX70813.1 - 1.6e-16 60.1 0.0 5.1e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 UBX domain Thioredoxin_7 PF13899.1 EPX70813.1 - 3.8e-16 58.8 0.0 7e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 EPX70813.1 - 5.5e-13 48.2 0.0 1e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredox_DsbH PF03190.10 EPX70813.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 DUF2890 PF11081.3 EPX70813.1 - 0.07 13.1 3.9 0.2 11.7 2.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Pkinase PF00069.20 EPX70814.1 - 1e-67 228.0 0.0 1.3e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70814.1 - 1.7e-44 151.8 0.0 2.2e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX70814.1 - 2.3e-06 26.7 0.0 0.0013 17.8 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 EPX70814.1 - 0.027 13.5 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX70814.1 - 0.073 12.7 0.0 0.57 9.8 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family ATP-synt_C PF00137.16 EPX70815.1 - 1.3e-26 92.2 27.5 3.4e-15 55.6 7.1 2.3 2 0 0 2 2 2 2 ATP synthase subunit C PTS_2-RNA PF01885.11 EPX70816.1 - 8.8e-59 197.9 0.0 1.4e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Yae1_N PF09811.4 EPX70816.1 - 2.3e-08 33.4 5.7 4.3e-08 32.5 4.0 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal KH_1 PF00013.24 EPX70817.1 - 0.0029 17.2 0.2 0.0079 15.8 0.1 1.7 1 0 0 1 1 1 1 KH domain MTBP_C PF14920.1 EPX70818.1 - 0.0011 18.5 2.3 0.0015 18.1 1.6 1.1 1 0 0 1 1 1 1 MDM2-binding DUF4164 PF13747.1 EPX70818.1 - 0.03 14.4 0.2 0.03 14.4 0.1 2.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4164) BLOC1_2 PF10046.4 EPX70818.1 - 0.064 13.3 2.9 6.2 7.0 0.1 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cluap1 PF10234.4 EPX70818.1 - 0.084 12.0 6.6 0.11 11.7 0.4 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF919 PF06034.6 EPX70818.1 - 0.11 12.1 3.0 1.1 8.9 0.1 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) CorA PF01544.13 EPX70818.1 - 0.12 11.3 1.4 0.16 10.9 1.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Exonuc_VII_S PF02609.11 EPX70818.1 - 0.13 12.0 3.4 0.89 9.3 0.8 2.5 2 0 0 2 2 2 0 Exonuclease VII small subunit DUF1635 PF07795.6 EPX70818.1 - 0.14 11.5 4.7 0.18 11.1 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) Streptin-Immun PF11083.3 EPX70818.1 - 0.15 12.0 5.3 0.29 11.1 0.2 2.7 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein ATG16 PF08614.6 EPX70818.1 - 0.23 11.2 9.4 0.12 12.1 4.6 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) H-kinase_dim PF02895.9 EPX70818.1 - 0.27 11.6 4.1 2.4 8.5 0.3 2.6 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain KLRAQ PF10205.4 EPX70818.1 - 0.42 10.6 6.8 0.16 12.0 1.9 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Fzo_mitofusin PF04799.8 EPX70818.1 - 0.71 9.2 4.4 0.47 9.8 0.3 2.1 2 1 0 2 2 2 0 fzo-like conserved region DivIVA PF05103.8 EPX70818.1 - 0.86 9.6 6.2 2.3 8.3 0.1 2.8 2 1 0 3 3 3 0 DivIVA protein APG6 PF04111.7 EPX70818.1 - 0.93 8.4 9.0 1.8 7.5 6.0 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF4446 PF14584.1 EPX70818.1 - 2 8.2 5.8 2.5 7.9 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) EAP30 PF04157.11 EPX70818.1 - 2 7.5 6.8 4.5 6.3 3.5 1.9 1 1 1 2 2 2 0 EAP30/Vps36 family GAS PF13851.1 EPX70818.1 - 2.3 7.3 12.7 2.4 7.2 2.2 2.1 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Rabaptin PF03528.10 EPX70818.1 - 2.5 8.0 7.2 5 7.0 1.0 2.3 2 0 0 2 2 2 0 Rabaptin Fib_alpha PF08702.5 EPX70818.1 - 2.5 8.2 7.7 3.3 7.8 0.8 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.8 EPX70818.1 - 3.2 8.5 8.9 3.9 8.2 1.8 2.4 1 1 1 2 2 2 0 Occludin homology domain DUF904 PF06005.7 EPX70818.1 - 5 7.4 7.3 21 5.5 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Cor1 PF04803.7 EPX70818.1 - 5.6 6.7 11.1 24 4.6 0.8 3.0 2 1 1 3 3 3 0 Cor1/Xlr/Xmr conserved region AATF-Che1 PF13339.1 EPX70818.1 - 7.1 6.7 9.2 3.5 7.7 2.4 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Rho_Binding PF08912.6 EPX70818.1 - 7.2 6.9 9.1 14 6.0 0.5 3.2 2 1 1 3 3 3 0 Rho Binding DUF1640 PF07798.6 EPX70819.1 - 7.9e-49 166.0 2.0 9.1e-49 165.8 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Pepsin-I3 PF06394.8 EPX70819.1 - 0.032 13.8 3.6 0.26 10.9 0.1 2.6 2 1 1 3 3 3 0 Pepsin inhibitor-3-like repeated domain Col_cuticle_N PF01484.12 EPX70819.1 - 0.054 13.1 0.1 16 5.2 0.0 3.1 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain Phage_glycop_gL PF11108.3 EPX70819.1 - 0.19 11.7 1.7 1.1 9.2 0.1 2.6 1 1 2 3 3 3 0 Viral glycoprotein L RNB PF00773.14 EPX70821.1 - 2.2e-98 329.5 1.7 5.7e-98 328.1 0.0 2.5 3 0 0 3 3 3 1 RNB domain OB_RNB PF08206.6 EPX70821.1 - 0.085 12.3 0.1 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain Nol1_Nop2_Fmu PF01189.12 EPX70822.1 - 2e-27 96.3 0.0 3.2e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EPX70822.1 - 0.00012 21.7 0.0 0.0003 20.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX70822.1 - 0.00012 22.6 0.0 0.00024 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPX70822.1 - 0.0006 18.9 0.0 0.0014 17.6 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_15 PF09445.5 EPX70822.1 - 0.0021 17.6 0.2 0.038 13.5 0.0 2.4 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Cornichon PF03311.9 EPX70823.1 - 2.6e-41 140.7 12.9 2.9e-41 140.6 8.9 1.0 1 0 0 1 1 1 1 Cornichon protein DUF2340 PF10209.4 EPX70824.1 - 1.5e-48 163.9 3.3 1.7e-48 163.8 2.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) ubiquitin PF00240.18 EPX70824.1 - 0.096 12.1 2.7 1.4 8.3 0.1 2.5 1 1 1 2 2 2 0 Ubiquitin family GABP-alpha PF11620.3 EPX70824.1 - 0.11 12.4 0.6 0.27 11.2 0.4 1.8 1 1 0 1 1 1 0 GA-binding protein alpha chain DUF2407 PF10302.4 EPX70824.1 - 0.17 12.0 0.6 0.3 11.3 0.4 1.6 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain ABC_tran PF00005.22 EPX70825.1 - 6.5e-45 152.7 0.0 1.6e-22 80.3 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EPX70825.1 - 9.3e-15 55.3 2.4 0.0018 18.3 0.0 4.3 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 EPX70825.1 - 1e-12 47.8 0.3 0.0085 15.3 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPX70825.1 - 1.6e-09 37.1 0.0 0.0014 18.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EPX70825.1 - 2.2e-08 34.7 0.9 0.0086 16.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EPX70825.1 - 5.6e-08 33.6 0.0 0.0082 16.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EPX70825.1 - 1.1e-07 31.3 0.2 0.16 10.9 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EPX70825.1 - 1.7e-07 31.4 0.0 0.025 14.6 0.0 4.3 5 1 0 5 5 3 2 AAA domain MMR_HSR1 PF01926.18 EPX70825.1 - 5.4e-07 29.5 0.0 0.07 13.0 0.0 3.3 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EPX70825.1 - 8.7e-07 28.6 0.0 0.05 13.0 0.0 3.4 4 0 0 4 4 4 2 AAA-like domain DUF258 PF03193.11 EPX70825.1 - 1.7e-06 27.3 0.0 0.0031 16.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EPX70825.1 - 2e-06 28.2 0.0 0.08 13.4 0.0 3.4 3 0 0 3 3 2 2 Miro-like protein MobB PF03205.9 EPX70825.1 - 3.2e-06 26.9 0.6 0.044 13.4 0.0 2.9 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EPX70825.1 - 8.4e-06 25.7 0.0 0.12 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EPX70825.1 - 3.4e-05 23.6 0.0 0.043 13.4 0.0 2.9 2 0 0 2 2 2 1 Archaeal ATPase DUF87 PF01935.12 EPX70825.1 - 4e-05 23.5 0.7 0.039 13.7 0.0 3.2 3 1 1 4 4 3 1 Domain of unknown function DUF87 AAA_18 PF13238.1 EPX70825.1 - 5.5e-05 23.4 0.1 0.16 12.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPX70825.1 - 5.7e-05 23.1 2.5 0.2 11.6 0.1 4.1 3 1 0 3 3 3 1 AAA ATPase domain Dynamin_N PF00350.18 EPX70825.1 - 7.4e-05 22.6 0.0 0.017 14.9 0.0 2.6 2 0 0 2 2 2 1 Dynamin family ArgK PF03308.11 EPX70825.1 - 0.0001 21.2 0.1 0.38 9.4 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_28 PF13521.1 EPX70825.1 - 0.00011 22.2 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EPX70825.1 - 0.00012 22.2 0.0 0.47 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 EPX70825.1 - 0.00012 22.3 0.1 0.79 9.9 0.0 3.8 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EPX70825.1 - 0.00014 21.7 0.0 0.26 11.2 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EPX70825.1 - 0.00016 21.5 0.0 1 9.2 0.0 3.5 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 EPX70825.1 - 0.00022 20.9 0.0 0.38 10.3 0.0 2.9 3 0 0 3 3 2 2 NACHT domain Zeta_toxin PF06414.7 EPX70825.1 - 0.0008 18.5 0.0 13 4.7 0.0 3.9 4 0 0 4 4 4 0 Zeta toxin MutS_V PF00488.16 EPX70825.1 - 0.00092 18.6 0.0 0.93 8.8 0.0 2.3 2 0 0 2 2 2 2 MutS domain V AAA_25 PF13481.1 EPX70825.1 - 0.0021 17.5 0.0 4.1 6.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EPX70825.1 - 0.0021 17.5 0.1 0.54 9.6 0.0 2.9 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 EPX70825.1 - 0.0069 14.9 0.3 2.8 6.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 EPX70825.1 - 0.0082 15.7 0.0 7 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EPX70825.1 - 0.011 15.5 0.1 2.6 7.8 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain T2SE PF00437.15 EPX70825.1 - 0.012 14.5 0.0 4 6.2 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 EPX70825.1 - 0.013 14.9 0.0 1.2 8.6 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 EPX70825.1 - 0.016 14.6 0.1 6.7 6.1 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family HEAT_EZ PF13513.1 EPX70825.1 - 0.023 15.2 1.5 15 6.2 0.1 4.4 5 0 0 5 5 3 0 HEAT-like repeat ATP_bind_1 PF03029.12 EPX70825.1 - 0.024 14.1 0.3 8.8 5.7 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.16 EPX70825.1 - 0.024 13.7 0.3 0.89 8.6 0.0 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EPX70825.1 - 0.031 13.1 0.0 6.4 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMS19_N PF14500.1 EPX70825.1 - 0.041 13.1 0.1 0.65 9.2 0.0 2.5 1 1 2 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II NTPase_1 PF03266.10 EPX70825.1 - 0.069 12.8 0.6 14 5.3 0.0 2.8 2 0 0 2 2 2 0 NTPase Adeno_IVa2 PF02456.10 EPX70825.1 - 0.073 11.7 0.0 5 5.6 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Microtub_assoc PF07989.6 EPX70826.1 - 5.5e-23 80.5 3.5 5.5e-23 80.5 2.5 10.4 9 3 3 12 12 12 1 Microtubule associated Mto2_bdg PF12808.2 EPX70826.1 - 1.2e-18 66.9 5.2 1.2e-18 66.9 3.6 6.2 8 0 0 8 8 8 1 Micro-tubular organiser Mto1 C-term Mto2-binding region IncA PF04156.9 EPX70826.1 - 0.0026 17.3 17.5 0.0026 17.3 12.1 8.7 3 2 4 7 7 7 2 IncA protein Reo_sigmaC PF04582.7 EPX70826.1 - 0.0027 16.9 3.3 0.0027 16.9 2.3 6.3 2 2 5 8 8 8 4 Reovirus sigma C capsid protein DUF2937 PF11157.3 EPX70826.1 - 0.047 13.0 17.3 0.77 9.0 0.2 5.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2937) AAA_13 PF13166.1 EPX70826.1 - 0.048 12.1 91.8 0.008 14.6 21.9 4.8 1 1 2 4 4 4 0 AAA domain OGFr_III PF04680.8 EPX70826.1 - 0.11 12.6 0.8 0.25 11.5 0.5 1.5 1 0 0 1 1 1 0 Opioid growth factor receptor repeat DUF948 PF06103.6 EPX70826.1 - 7.6 6.4 36.7 0.49 10.2 0.5 7.3 4 2 2 7 7 7 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.20 EPX70827.1 - 7.1e-57 192.5 2.1 9.7e-57 192.0 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70827.1 - 2.4e-28 98.9 0.5 1.3e-20 73.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EPX70827.1 - 0.00049 20.5 0.1 0.0012 19.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPX70827.1 - 0.019 13.9 0.0 0.019 13.9 0.0 2.9 3 0 0 3 3 3 0 Kinase-like DASH_Hsk3 PF08227.6 EPX70828.1 - 1.4e-17 63.5 7.8 2e-17 63.1 5.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like DASH_Dam1 PF08653.5 EPX70828.1 - 0.016 14.9 0.4 0.028 14.1 0.3 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 DUF550 PF04447.7 EPX70828.1 - 0.022 14.3 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF550) Methyltransf_17 PF12692.2 EPX70828.1 - 0.023 14.3 0.1 0.027 14.1 0.1 1.0 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase DNA_photolyase PF00875.13 EPX70828.1 - 0.089 12.5 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 DNA photolyase Leader_Thr PF08254.6 EPX70828.1 - 0.22 11.2 1.4 0.34 10.6 1.0 1.3 1 0 0 1 1 1 0 Threonine leader peptide GvpK PF05121.7 EPX70828.1 - 0.26 11.1 2.0 1.9 8.3 0.2 2.0 1 1 1 2 2 2 0 Gas vesicle protein K GATA PF00320.22 EPX70829.1 - 4.2e-16 57.9 1.9 1e-15 56.7 1.3 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EPX70829.1 - 3.7e-11 42.3 2.4 6.4e-11 41.6 1.6 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ApbA PF02558.11 EPX70830.1 - 1.2e-23 83.2 0.0 1.8e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EPX70830.1 - 1.8e-18 66.7 0.0 3.6e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DUF3818 PF12825.2 EPX70831.1 - 1.1e-51 175.6 2.7 6.4e-40 136.8 0.0 3.0 2 1 1 3 3 3 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EPX70831.1 - 6.1e-22 77.6 0.0 1.2e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 PX-associated TRP PF06011.7 EPX70832.1 - 1.2e-64 218.4 23.3 1.2e-64 218.4 16.2 1.4 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPX70832.1 - 4.9e-32 110.8 1.2 5e-32 110.8 0.1 1.6 2 0 0 2 2 2 1 ML-like domain Acetyltransf_1 PF00583.19 EPX70833.1 - 2.4e-10 40.3 0.0 3.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPX70833.1 - 4e-07 30.1 0.0 5.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPX70833.1 - 8.3e-07 29.1 0.0 1e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EPX70833.1 - 0.00067 19.2 0.0 0.00077 19.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPX70833.1 - 0.0045 16.8 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.1 EPX70833.1 - 0.046 13.6 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPX70833.1 - 0.072 13.0 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAP_assoc PF03828.14 EPX70834.1 - 6.1e-13 48.5 0.1 1.3e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Wbp11 PF09429.5 EPX70835.1 - 2.1e-18 66.0 11.7 2.1e-18 66.0 8.1 2.9 2 1 0 2 2 2 1 WW domain binding protein 11 NpwBP PF12622.2 EPX70835.1 - 1.2e-12 48.0 5.7 1.2e-12 48.0 4.0 3.0 3 0 0 3 3 3 1 mRNA biogenesis factor AdoMet_MTase PF07757.8 EPX70836.1 - 1.9e-50 169.6 0.2 3.7e-50 168.7 0.2 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 EPX70836.1 - 0.00025 20.7 0.0 0.003 17.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX70836.1 - 0.018 14.7 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.12 EPX70836.1 - 0.025 13.9 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase L51_S25_CI-B8 PF05047.11 EPX70837.1 - 1.7e-06 27.6 0.1 3e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RNA_pol_A_bac PF01000.21 EPX70838.1 - 1.3e-32 112.3 0.0 2.8e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EPX70838.1 - 2.5e-15 55.3 0.0 3.1e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 EPX70838.1 - 0.14 11.6 0.0 0.41 10.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF22 Chorismate_bind PF00425.13 EPX70839.1 - 3.1e-90 301.9 0.0 4.1e-90 301.5 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EPX70839.1 - 1.1e-26 93.5 0.1 3.5e-24 85.4 0.0 3.0 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region COX6B PF02297.12 EPX70840.1 - 4.1e-20 71.5 5.2 5e-20 71.2 3.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 EPX70840.1 - 0.089 12.7 0.3 0.089 12.7 0.2 1.6 2 0 0 2 2 2 0 CHCH domain UCR_hinge PF02320.11 EPX70840.1 - 0.2 11.6 1.8 0.42 10.5 0.3 2.0 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 EPX70840.1 - 1.1 9.1 4.5 1.7 8.5 0.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) WLM PF08325.5 EPX70841.1 - 1.3e-39 136.0 1.8 1.3e-39 136.0 1.2 2.3 1 1 2 3 3 3 1 WLM domain ubiquitin PF00240.18 EPX70841.1 - 7.7e-07 28.4 1.2 1.1e-06 27.8 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family DUF45 PF01863.12 EPX70841.1 - 0.0006 19.6 3.6 0.0046 16.7 2.5 2.5 1 1 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_MA_2 PF13485.1 EPX70841.1 - 0.0034 17.4 1.6 0.077 13.0 0.4 2.3 2 0 0 2 2 2 1 Peptidase MA superfamily SprT-like PF10263.4 EPX70841.1 - 0.03 13.9 0.5 0.047 13.3 0.4 1.3 1 0 0 1 1 1 0 SprT-like family Proteasome PF00227.21 EPX70842.1 - 1.1e-58 197.7 0.1 1.5e-58 197.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPX70842.1 - 2e-10 39.7 0.3 4.9e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ApoO PF09769.4 EPX70845.1 - 5e-22 78.3 0.5 3.8e-21 75.4 0.0 1.9 1 1 1 2 2 2 1 Apolipoprotein O Ca_hom_mod PF14798.1 EPX70845.1 - 0.00078 18.4 0.0 0.00093 18.2 0.0 1.2 1 0 0 1 1 1 1 Calcium homeostasis modulator Bromodomain PF00439.20 EPX70846.1 - 2.1e-48 162.1 0.2 5.3e-23 80.7 0.0 2.4 2 0 0 2 2 2 2 Bromodomain Utp12 PF04003.7 EPX70847.1 - 1.1e-05 25.2 0.0 1.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family EF1_GNE PF00736.14 EPX70848.1 - 4e-29 100.1 0.4 7.5e-29 99.2 0.3 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EPX70848.1 - 1.7e-11 44.0 4.3 5.2e-11 42.4 3.0 1.9 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EPX70848.1 - 0.00036 20.9 0.0 0.0012 19.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPX70848.1 - 0.0091 15.8 1.0 0.15 11.9 0.2 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPX70848.1 - 0.07 13.1 1.6 0.17 11.9 0.0 2.4 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Rox3 PF08633.5 EPX70849.1 - 2.6e-18 67.0 0.1 3.9e-18 66.4 0.0 1.2 1 1 0 1 1 1 1 Rox3 mediator complex subunit Glutaredoxin PF00462.19 EPX70850.1 - 1.6e-12 47.2 0.0 2.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DAO PF01266.19 EPX70851.1 - 6.4e-22 77.9 0.0 9.5e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPX70851.1 - 0.0031 17.5 0.2 0.0093 15.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPX70851.1 - 0.011 16.1 0.2 0.024 15.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPX70851.1 - 0.033 13.2 0.0 0.072 12.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EPX70851.1 - 0.058 12.4 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Fe_hyd_lg_C PF02906.9 EPX70852.1 - 4.4e-72 242.7 0.0 8.7e-71 238.4 0.0 2.2 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain EF-hand_8 PF13833.1 EPX70852.1 - 0.12 11.9 0.1 0.51 9.9 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain pair Pkinase PF00069.20 EPX70853.1 - 9.5e-59 198.6 0.0 3.8e-37 127.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70853.1 - 1.2e-26 93.3 0.0 1.7e-21 76.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPX70853.1 - 1.6e-05 24.0 0.0 0.00058 18.9 0.0 2.4 2 0 0 2 2 2 1 Kinase-like PAS_9 PF13426.1 EPX70853.1 - 0.00051 20.3 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain APH PF01636.18 EPX70853.1 - 0.0009 19.0 0.0 0.2 11.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPX70853.1 - 0.0077 15.1 0.2 3.4 6.4 0.0 2.4 2 0 0 2 2 2 2 Seadornavirus VP7 PAS_4 PF08448.5 EPX70853.1 - 0.017 15.1 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS PF00989.19 EPX70853.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 PAS fold DUF3818 PF12825.2 EPX70854.1 - 2.2e-101 338.9 5.4 2.2e-101 338.9 3.8 1.9 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EPX70854.1 - 4.6e-27 94.2 0.4 1.1e-26 93.0 0.3 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EPX70854.1 - 7.6e-15 54.6 0.1 2.8e-14 52.8 0.1 2.0 1 0 0 1 1 1 1 PX domain Lum_binding PF00677.12 EPX70855.1 - 5.2e-46 154.4 1.0 1.1e-23 82.8 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain ERO1 PF04137.10 EPX70856.1 - 5.2e-123 410.5 1.1 6.5e-123 410.2 0.8 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Fer4_18 PF13746.1 EPX70856.1 - 0.027 14.8 0.1 0.089 13.2 0.1 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain PIG-F PF06699.6 EPX70857.1 - 8.7e-39 133.4 14.3 1.5e-38 132.6 9.9 1.4 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F adh_short PF00106.20 EPX70857.1 - 6.9e-21 74.8 0.0 9.4e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPX70857.1 - 2.5e-08 33.7 0.0 3.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPX70857.1 - 0.00013 21.7 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPX70857.1 - 0.001 18.5 0.0 0.0054 16.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EPX70857.1 - 0.0029 16.7 0.0 0.0046 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EPX70857.1 - 0.0035 17.0 0.0 0.0096 15.6 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EPX70857.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding DUF3336 PF11815.3 EPX70858.1 - 5.8e-32 110.1 0.1 1.1e-31 109.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EPX70858.1 - 2.5e-09 37.3 0.3 5.2e-07 29.8 0.0 2.3 1 1 1 2 2 2 2 Patatin-like phospholipase RasGEF PF00617.14 EPX70859.1 - 2.1e-52 177.5 2.1 4.4e-52 176.5 0.7 2.2 2 0 0 2 2 2 1 RasGEF domain SH3_1 PF00018.23 EPX70859.1 - 1.1e-09 37.5 0.0 2.2e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain RasGEF_N PF00618.15 EPX70859.1 - 1.2e-09 38.1 3.3 2.8e-09 37.0 0.8 2.8 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 EPX70859.1 - 9e-09 34.7 0.0 1.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPX70859.1 - 2.8e-05 23.5 0.0 5.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kinetochor_Ybp2 PF08568.5 EPX70860.1 - 2.4e-38 131.8 13.4 5.6e-24 84.3 1.8 2.1 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Mito_carr PF00153.22 EPX70861.1 - 3.7e-70 231.7 1.2 4.1e-26 90.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 EPX70861.1 - 0.00099 19.4 0.3 0.81 10.0 0.2 2.4 2 0 0 2 2 2 2 YtxH-like protein DUF2420 PF10336.4 EPX70862.1 - 1.1e-24 86.2 0.4 2.1e-24 85.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) CDP-OH_P_transf PF01066.16 EPX70863.1 - 2.7e-13 50.0 5.3 2.7e-13 50.0 3.6 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase G-patch PF01585.18 EPX70864.1 - 1e-13 50.8 5.2 1e-13 50.8 3.6 1.7 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EPX70864.1 - 0.0063 16.3 0.8 0.018 14.8 0.6 1.9 1 1 0 1 1 1 1 DExH-box splicing factor binding site HIT PF01230.18 EPX70865.1 - 7.3e-24 84.1 0.1 8.9e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPX70865.1 - 3.4e-13 49.8 0.0 4.3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EPX70865.1 - 0.00067 19.2 0.0 0.00085 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 60KD_IMP PF02096.15 EPX70866.1 - 2.8e-29 102.1 0.7 3.5e-29 101.8 0.5 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein ADH_zinc_N PF00107.21 EPX70867.1 - 2.7e-24 85.1 0.0 4.2e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPX70867.1 - 2.9e-11 44.3 0.0 5.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPX70867.1 - 5.2e-11 42.2 0.0 2e-09 37.1 0.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EPX70867.1 - 0.013 15.3 0.2 0.31 10.9 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Cpn10 PF00166.16 EPX70867.1 - 0.075 12.9 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit Ist1 PF03398.9 EPX70868.1 - 6.6e-33 113.4 0.1 9.5e-33 112.9 0.1 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Roughex PF06020.6 EPX70868.1 - 0.0032 16.2 2.4 0.0043 15.7 1.7 1.1 1 0 0 1 1 1 1 Drosophila roughex protein DEAD PF00270.24 EPX70869.1 - 4.8e-43 146.5 0.0 1e-42 145.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX70869.1 - 1.5e-21 75.9 0.0 3.3e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX70869.1 - 2.4e-12 47.0 0.7 2.2e-10 40.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPX70869.1 - 0.0014 17.4 0.1 0.019 13.7 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain DDE_3 PF13358.1 EPX70869.1 - 0.06 13.0 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease AAA_22 PF13401.1 EPX70869.1 - 1.3 9.2 3.6 7.9 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain Transthyretin PF00576.16 EPX70870.1 - 3.7e-36 123.4 0.1 4.2e-36 123.2 0.1 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.1 EPX70870.1 - 0.0047 16.9 1.9 0.056 13.4 1.3 2.0 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain phage_tail_N PF08400.5 EPX70870.1 - 0.22 11.2 1.0 3.2 7.4 0.7 2.0 1 1 0 1 1 1 0 Prophage tail fibre N-terminal NUP PF06516.6 EPX70871.1 - 5.4e-103 344.1 0.6 6.2e-103 343.9 0.4 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) NMT1 PF09084.6 EPX70872.1 - 2.4e-73 246.2 0.0 3.2e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EPX70872.1 - 0.00034 20.0 0.0 0.0016 17.8 0.0 2.1 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.2 EPX70872.1 - 0.0058 16.0 0.0 0.0089 15.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.2 EPX70872.1 - 0.17 10.8 0.0 1.6 7.6 0.0 2.2 1 1 1 2 2 2 0 PBP superfamily domain SET PF00856.23 EPX70873.1 - 2.9e-10 40.6 0.0 5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 SET domain DASH_Spc19 PF08287.6 EPX70874.1 - 4.7e-34 117.2 9.4 2.6e-33 114.8 6.5 1.8 1 1 0 1 1 1 1 Spc19 Cep57_CLD_2 PF14197.1 EPX70874.1 - 0.0096 15.8 3.3 0.0096 15.8 2.3 2.4 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 DASH_Dam1 PF08653.5 EPX70874.1 - 0.031 14.0 0.2 4.9 6.9 0.0 2.7 2 1 0 2 2 2 0 DASH complex subunit Dam1 FlaC_arch PF05377.6 EPX70874.1 - 0.063 13.1 0.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.12 EPX70874.1 - 0.086 12.4 5.7 2.8 7.6 0.0 3.2 3 1 0 3 3 3 0 Prefoldin subunit DivIC PF04977.10 EPX70874.1 - 0.11 11.9 4.3 0.96 8.9 1.1 2.8 1 1 2 3 3 3 0 Septum formation initiator Muted PF14942.1 EPX70874.1 - 0.12 12.2 2.4 0.37 10.6 0.8 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Snapin_Pallidin PF14712.1 EPX70874.1 - 0.18 12.1 6.1 4.7 7.5 0.0 2.9 1 1 2 3 3 3 0 Snapin/Pallidin Prefoldin_2 PF01920.15 EPX70874.1 - 3.5 7.4 7.7 1.2 8.9 1.0 2.9 3 1 0 3 3 3 0 Prefoldin subunit Ribosomal_L37e PF01907.14 EPX70875.1 - 9.4e-26 89.3 14.5 1.6e-25 88.6 10.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EPX70875.1 - 0.00099 18.8 2.7 0.0014 18.3 1.9 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-C3HC4_2 PF13923.1 EPX70875.1 - 0.11 12.5 3.8 0.17 11.9 2.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX70875.1 - 0.13 12.0 3.5 0.19 11.4 2.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain HypA PF01155.14 EPX70875.1 - 0.22 11.2 1.3 0.31 10.7 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family GATA PF00320.22 EPX70875.1 - 0.43 9.9 6.8 0.48 9.8 1.0 2.3 1 1 1 2 2 2 0 GATA zinc finger zf-ribbon_3 PF13248.1 EPX70875.1 - 0.49 9.6 3.8 1.8 7.8 2.7 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Neuropeptide_S PF14993.1 EPX70875.1 - 0.58 9.8 2.6 0.58 9.8 0.3 2.2 2 1 1 3 3 3 0 Neuropeptide S precursor protein zf-C3HC4 PF00097.20 EPX70875.1 - 0.81 9.4 5.4 1.2 8.8 3.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.1 EPX70875.1 - 0.87 9.1 6.3 1.6 8.2 4.4 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DNA_RNApol_7kD PF03604.8 EPX70875.1 - 7.4 6.1 7.3 4.6 6.7 1.2 2.2 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Kelch_4 PF13418.1 EPX70876.1 - 5.5e-47 157.3 9.1 4.5e-12 45.5 0.0 6.6 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EPX70876.1 - 7.6e-47 156.5 9.0 1e-10 41.4 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EPX70876.1 - 2e-37 126.5 11.7 2.1e-08 33.9 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EPX70876.1 - 3.7e-33 112.3 8.2 8.6e-09 35.1 0.1 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EPX70876.1 - 4.4e-32 109.3 0.1 3.7e-09 35.9 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EPX70876.1 - 1e-28 97.9 3.0 4.2e-06 26.3 0.1 5.7 5 0 0 5 5 5 5 Kelch motif HALZ PF02183.13 EPX70876.1 - 2.2 8.0 9.0 0.2 11.4 1.0 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper tRNA-synt_2 PF00152.15 EPX70877.1 - 1.5e-78 263.9 0.1 2.4e-78 263.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPX70877.1 - 7.8e-06 25.6 0.3 1.4e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EPX70877.1 - 0.02 14.1 0.2 2.8 7.0 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF4557 PF15101.1 EPX70877.1 - 0.22 11.3 1.3 0.38 10.5 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FSH1 PF03959.8 EPX70878.1 - 5.3e-62 209.0 0.0 8.3e-62 208.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DHFR_1 PF00186.14 EPX70878.1 - 3.1e-25 88.6 0.0 4.3e-24 84.9 0.0 2.1 1 1 0 1 1 1 1 Dihydrofolate reductase Abhydrolase_5 PF12695.2 EPX70878.1 - 5.5e-09 35.9 0.0 5.6e-08 32.6 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPX70878.1 - 0.0013 18.6 0.0 3.3 7.5 0.0 3.2 2 1 1 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPX70878.1 - 0.047 13.1 0.1 0.13 11.7 0.1 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Uricase PF01014.13 EPX70879.1 - 1.4e-70 235.7 4.0 4.8e-37 127.1 1.7 2.0 2 0 0 2 2 2 2 Uricase EAF PF09816.4 EPX70880.1 - 2e-21 76.0 0.0 3.7e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor AICARFT_IMPCHas PF01808.13 EPX70882.1 - 1.7e-118 395.3 0.0 2.2e-118 394.9 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EPX70882.1 - 1.8e-24 85.5 0.0 3.3e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Methyltransf_4 PF02390.12 EPX70883.1 - 8.5e-51 171.8 0.0 1.1e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EPX70883.1 - 0.00013 22.5 0.0 0.00022 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPX70883.1 - 0.00049 19.5 0.0 0.0013 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 EPX70883.1 - 0.00049 19.1 0.0 0.00079 18.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 EPX70883.1 - 0.0013 18.3 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EPX70883.1 - 0.0032 17.1 0.0 0.0059 16.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX70883.1 - 0.0053 17.0 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX70883.1 - 0.0054 17.1 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX70883.1 - 0.046 14.2 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EPX70883.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EPX70883.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase cobW PF02492.14 EPX70884.1 - 1e-34 119.4 0.0 1.3e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EPX70884.1 - 0.00031 19.6 1.6 0.0038 16.0 1.1 2.0 1 1 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 EPX70884.1 - 0.0024 18.6 0.0 0.0052 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPX70884.1 - 0.0039 16.6 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPX70884.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EPX70884.1 - 0.014 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Pox_A32 PF04665.7 EPX70884.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.7 EPX70884.1 - 0.04 13.5 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EPX70884.1 - 0.1 12.6 0.1 0.18 11.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EPX70884.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EPX70884.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase NTPase_1 PF03266.10 EPX70884.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 NTPase MobB PF03205.9 EPX70884.1 - 0.57 9.8 0.0 0.57 9.8 0.0 2.4 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B PBP1_TM PF14812.1 EPX70887.1 - 0.00094 19.4 0.2 0.0013 19.0 0.1 1.3 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 EPX70887.1 - 0.0088 15.8 1.0 0.0094 15.7 0.7 1.1 1 0 0 1 1 1 1 RXT2-like, N-terminal Use1 PF09753.4 EPX70887.1 - 0.052 12.9 1.5 0.089 12.2 1.1 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 DEAD PF00270.24 EPX70888.1 - 1.6e-44 151.3 0.0 8e-44 149.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX70888.1 - 7.7e-27 92.9 0.1 1.6e-26 91.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX70888.1 - 0.028 14.2 0.0 0.1 12.4 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EPX70888.1 - 0.031 12.6 0.0 0.069 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) Erv26 PF04148.8 EPX70889.1 - 2.6e-67 226.3 7.0 3e-67 226.1 4.8 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 BatA PF07584.6 EPX70889.1 - 0.57 10.4 4.6 1.2 9.3 2.8 2.0 1 1 0 1 1 1 0 Aerotolerance regulator N-terminal Asp PF00026.18 EPX70890.1 - 3.8e-32 111.8 4.5 4.9e-32 111.4 3.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPX70890.1 - 6.5e-05 22.9 0.0 0.002 18.1 0.0 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal HSA PF07529.8 EPX70891.1 - 1.7e-17 62.9 1.2 1.3e-16 60.1 0.1 2.8 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 EPX70891.1 - 2.2e-11 43.6 0.1 9.3e-11 41.6 0.1 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPX70891.1 - 0.0047 16.9 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_S13 PF00416.17 EPX70892.1 - 4.1e-29 101.1 0.0 5.3e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EPX70892.1 - 0.0022 16.6 0.0 0.0024 16.5 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HPS3_N PF14761.1 EPX70893.1 - 1.6e-05 24.4 11.8 1.4 8.3 0.1 4.1 1 1 2 4 4 4 4 Hermansky-Pudlak syndrome 3 BOFC_N PF08977.5 EPX70893.1 - 0.086 12.6 8.9 14 5.6 0.0 4.2 4 0 0 4 4 4 0 Bypass of Forespore C, N terminal DIM PF08194.7 EPX70893.1 - 0.16 11.9 1.4 0.23 11.4 1.0 1.2 1 0 0 1 1 1 0 DIM protein Cylicin_N PF15241.1 EPX70893.1 - 0.95 9.3 3.8 88 3.0 0.0 3.9 4 0 0 4 4 4 0 Cylicin N-terminus ADK PF00406.17 EPX70894.1 - 2.9e-39 134.3 0.0 3.4e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EPX70894.1 - 3.1e-09 37.2 0.0 6.4e-09 36.1 0.0 1.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EPX70894.1 - 2e-06 28.6 0.0 2.6e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EPX70894.1 - 2.1e-05 24.0 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 EPX70894.1 - 0.00016 21.6 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPX70894.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Proteasome PF00227.21 EPX70895.1 - 3.9e-47 160.0 0.0 4.7e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPX70895.1 - 2e-09 36.5 0.4 3.5e-09 35.8 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nuc_sug_transp PF04142.10 EPX70896.1 - 1.8e-92 308.8 13.5 3.3e-92 308.0 9.3 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EPX70896.1 - 6.1e-11 41.7 13.8 7.8e-11 41.4 9.5 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EPX70896.1 - 1.6e-06 27.8 23.3 0.00012 21.7 0.6 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EPX70896.1 - 9.7e-06 25.7 1.8 9.7e-06 25.7 1.2 2.6 3 0 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EPX70896.1 - 8e-05 22.6 2.7 8e-05 22.6 1.9 3.5 2 1 1 3 3 3 1 EamA-like transporter family Na_Ca_ex PF01699.19 EPX70897.1 - 8.1e-43 145.3 38.5 1.8e-23 82.6 8.5 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF1980 PF09323.5 EPX70897.1 - 0.062 13.0 0.1 0.22 11.2 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) DUF1109 PF06532.6 EPX70897.1 - 3 7.2 15.3 0.18 11.1 5.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1109) Mad3_BUB1_I PF08311.7 EPX70898.1 - 1.1e-43 148.0 1.2 2.2e-43 147.0 0.9 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Troponin PF00992.15 EPX70898.1 - 0.0072 16.3 0.4 0.012 15.6 0.3 1.3 1 0 0 1 1 1 1 Troponin Sua5_yciO_yrdC PF01300.13 EPX70899.1 - 1.9e-50 170.5 0.0 7e-50 168.7 0.0 1.8 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 EPX70899.1 - 2.5e-30 105.1 0.0 4.6e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DGF-1_4 PF11024.3 EPX70899.1 - 0.013 15.8 0.4 3.6 8.0 0.0 3.2 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Syntaxin-18_N PF10496.4 EPX70900.1 - 2.5e-10 40.0 0.5 2.6e-09 36.7 0.0 2.7 2 1 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus BRE1 PF08647.6 EPX70900.1 - 0.02 14.8 0.6 0.02 14.8 0.4 2.7 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase MCPsignal PF00015.16 EPX70900.1 - 0.058 12.9 4.0 0.11 12.0 0.6 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FH2 PF02181.18 EPX70901.1 - 5e-51 173.7 0.1 5e-51 173.7 0.0 2.3 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EPX70901.1 - 2.7e-18 66.1 4.4 2.7e-18 66.1 3.0 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EPX70901.1 - 2.7e-05 23.6 4.7 3.5e-05 23.2 0.0 3.1 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain WD40 PF00400.27 EPX70902.1 - 8.9e-57 187.0 15.0 1.8e-07 30.7 0.0 11.1 12 0 0 12 12 12 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 EPX70902.1 - 0.07 12.9 0.5 19 5.0 0.0 4.4 5 1 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 EPX70903.1 - 3.4e-08 32.9 0.2 0.19 11.8 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat CLASP_N PF12348.3 EPX70903.1 - 3.2e-07 29.9 0.9 7.1e-07 28.8 0.6 1.5 1 0 0 1 1 1 1 CLASP N terminal TAN PF11640.3 EPX70903.1 - 0.0028 17.3 0.8 0.0079 15.9 0.6 1.8 1 1 0 1 1 1 1 Telomere-length maintenance and DNA damage repair NYD-SP28_assoc PF14775.1 EPX70903.1 - 0.038 13.6 0.5 0.13 12.0 0.3 1.9 1 0 0 1 1 1 0 Sperm tail C-terminal domain ox_reductase_C PF08635.5 EPX70903.1 - 0.12 11.8 0.0 3.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Putative oxidoreductase C terminal IncA PF04156.9 EPX70903.1 - 3.7 7.1 9.1 1.1 8.8 2.7 2.5 3 0 0 3 3 3 0 IncA protein OKR_DC_1_N PF03709.10 EPX70904.1 - 0.089 12.8 0.0 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Spo0M PF07070.6 EPX70904.1 - 0.19 11.0 0.1 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein HA2 PF04408.18 EPX70905.1 - 2.4e-15 56.3 0.0 9.5e-15 54.4 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EPX70905.1 - 2.1e-12 46.8 0.0 7e-12 45.1 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EPX70905.1 - 3.5e-12 46.0 0.1 1.3e-11 44.1 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RWD PF05773.17 EPX70905.1 - 1e-09 38.3 0.5 3.7e-09 36.4 0.3 2.0 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EPX70905.1 - 1.8e-08 34.0 0.7 6.1e-08 32.3 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase UBA PF00627.26 EPX70905.1 - 6.4e-05 22.6 0.1 0.015 15.1 0.0 3.1 3 0 0 3 3 3 1 UBA/TS-N domain AAA_22 PF13401.1 EPX70905.1 - 0.00012 22.2 0.1 0.00031 20.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EPX70905.1 - 0.0021 17.0 0.0 0.0042 16.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EPX70905.1 - 0.0029 17.6 1.4 0.0066 16.4 0.2 2.3 2 1 0 2 2 1 1 AAA ATPase domain KaiC PF06745.8 EPX70905.1 - 0.047 12.7 0.0 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.1 EPX70905.1 - 0.082 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EPX70905.1 - 0.11 12.0 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SH3BGR PF04908.10 EPX70905.1 - 0.13 12.1 5.0 0.33 10.9 0.0 3.8 4 1 1 5 5 5 0 SH3-binding, glutamic acid-rich protein ABC_tran PF00005.22 EPX70906.1 - 1.6e-40 138.6 0.0 3.3e-21 76.0 0.0 3.9 4 1 0 4 4 3 2 ABC transporter AAA_21 PF13304.1 EPX70906.1 - 1.5e-18 67.7 13.0 3.4e-06 27.2 0.0 5.2 5 0 0 5 5 5 4 AAA domain ABC_tran_2 PF12848.2 EPX70906.1 - 4.2e-09 36.1 7.4 4.2e-09 36.1 5.1 5.0 4 1 1 5 5 4 1 ABC transporter AAA_29 PF13555.1 EPX70906.1 - 1.5e-06 27.6 0.1 0.038 13.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EPX70906.1 - 2e-06 27.1 20.5 0.022 14.0 5.6 5.3 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA PF00004.24 EPX70906.1 - 4.9e-06 26.7 0.3 0.044 13.9 0.0 3.9 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPX70906.1 - 5.3e-06 26.6 0.1 0.015 15.4 0.0 3.8 3 1 0 3 3 3 1 AAA domain Miro PF08477.8 EPX70906.1 - 2.6e-05 24.6 2.1 0.1 13.1 0.0 3.8 4 0 0 4 4 2 2 Miro-like protein AAA_16 PF13191.1 EPX70906.1 - 3e-05 24.0 0.1 0.011 15.7 0.1 3.3 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EPX70906.1 - 5.8e-05 22.3 0.0 0.01 15.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EPX70906.1 - 6.3e-05 22.6 0.1 0.0068 16.1 0.1 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EPX70906.1 - 0.00011 21.8 0.1 0.47 10.2 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 EPX70906.1 - 0.00013 21.8 0.0 0.013 15.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EPX70906.1 - 0.00021 21.1 1.9 0.6 10.0 0.0 3.7 3 1 0 3 3 3 2 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 EPX70906.1 - 0.00063 19.2 0.0 0.031 13.7 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EPX70906.1 - 0.001 19.4 0.9 0.025 14.9 0.1 5.5 5 1 0 6 6 5 2 AAA domain AAA_25 PF13481.1 EPX70906.1 - 0.0014 18.0 1.8 1.5 8.2 0.1 3.3 3 1 0 3 3 2 2 AAA domain AAA_28 PF13521.1 EPX70906.1 - 0.0017 18.3 0.0 0.14 12.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EPX70906.1 - 0.0023 17.5 0.0 0.34 10.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 EPX70906.1 - 0.004 16.6 0.0 0.082 12.3 0.0 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EPX70906.1 - 0.0041 17.0 0.1 2.9 7.7 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EPX70906.1 - 0.0064 15.9 3.7 1.1 8.5 0.0 3.9 4 1 1 5 5 4 1 AAA-like domain MMR_HSR1 PF01926.18 EPX70906.1 - 0.0069 16.3 0.0 0.4 10.6 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.9 EPX70906.1 - 0.0072 16.0 0.1 0.71 9.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EPX70906.1 - 0.014 15.1 0.2 0.47 10.1 0.1 2.6 2 0 0 2 2 2 0 NTPase DUF3584 PF12128.3 EPX70906.1 - 0.021 12.1 0.1 0.021 12.1 0.1 3.4 3 0 0 3 3 2 0 Protein of unknown function (DUF3584) AAA_17 PF13207.1 EPX70906.1 - 0.025 15.3 11.7 0.033 15.0 0.0 4.5 4 1 0 4 4 3 0 AAA domain AAA_18 PF13238.1 EPX70906.1 - 0.046 14.0 0.0 0.046 14.0 0.0 4.8 5 1 0 5 5 4 0 AAA domain RNA_helicase PF00910.17 EPX70906.1 - 0.06 13.5 0.0 4.4 7.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase PRKCSH-like PF12999.2 EPX70907.1 - 1.9e-65 219.6 8.6 1.9e-65 219.6 6.0 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EPX70907.1 - 1.5e-50 170.6 1.5 1.5e-50 170.6 1.0 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 EPX70907.1 - 0.0039 17.0 21.3 0.19 11.6 8.1 2.7 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A ACT_3 PF10000.4 EPX70907.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 ACT domain ArdA PF07275.6 EPX70907.1 - 0.077 13.2 4.8 0.17 12.1 3.3 1.5 1 0 0 1 1 1 0 Antirestriction protein (ArdA) Med28 PF11594.3 EPX70907.1 - 1.6 9.0 13.9 0.062 13.5 2.0 3.2 2 1 1 3 3 3 0 Mediator complex subunit 28 DUF2990 PF11693.3 EPX70907.1 - 2.1 8.2 4.3 5 7.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2990) DUF948 PF06103.6 EPX70907.1 - 4 7.3 10.0 3.4 7.5 0.0 3.9 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 EPX70907.1 - 4.4 5.6 14.2 2 6.7 1.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF342) DUF3053 PF11254.3 EPX70907.1 - 5.1 6.2 7.2 1.4 8.1 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3053) Cep57_MT_bd PF06657.8 EPX70907.1 - 6.8 6.7 11.4 0.91 9.5 0.6 3.1 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 FlaC_arch PF05377.6 EPX70907.1 - 7.7 6.5 11.8 8.5 6.3 0.7 3.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) MerR-DNA-bind PF09278.6 EPX70907.1 - 8.8 6.8 6.2 1.9 8.9 0.2 2.7 3 0 0 3 3 3 0 MerR, DNA binding SNARE PF05739.14 EPX70908.1 - 1.3e-17 63.1 2.1 1.3e-17 63.1 1.4 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EPX70908.1 - 1e-15 57.7 8.8 4.9e-15 55.5 3.2 2.3 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EPX70908.1 - 1e-05 25.2 6.4 0.0048 16.4 1.8 2.2 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.7 EPX70908.1 - 0.0079 16.4 5.5 0.18 12.0 0.6 2.5 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 EPX70908.1 - 0.01 15.9 1.0 7.2 6.8 0.0 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Allexi_40kDa PF05549.6 EPX70908.1 - 0.014 14.7 4.0 0.016 14.4 0.5 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein Prominin PF05478.6 EPX70908.1 - 0.021 12.4 0.1 0.021 12.4 0.1 2.0 1 1 1 2 2 2 0 Prominin Vac_Fusion PF02346.11 EPX70908.1 - 0.029 13.7 1.1 2 7.9 0.0 3.0 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Vps51 PF08700.6 EPX70908.1 - 0.048 13.5 0.7 0.61 9.9 0.0 2.9 2 1 1 3 3 3 0 Vps51/Vps67 Skp1 PF01466.14 EPX70908.1 - 0.07 13.1 0.8 0.19 11.8 0.6 1.8 1 0 0 1 1 1 0 Skp1 family, dimerisation domain V-SNARE PF05008.10 EPX70908.1 - 0.084 13.0 0.4 0.084 13.0 0.3 3.2 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Med4 PF10018.4 EPX70908.1 - 0.1 11.9 0.1 0.1 11.9 0.1 2.7 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Toxin_52 PF15605.1 EPX70908.1 - 0.14 12.0 1.7 12 5.8 0.1 3.4 1 1 2 4 4 4 0 Putative toxin 52 DUF4094 PF13334.1 EPX70908.1 - 0.32 11.4 3.5 0.53 10.6 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Med28 PF11594.3 EPX70908.1 - 1.9 8.7 5.3 22 5.3 2.4 2.5 1 1 1 2 2 2 0 Mediator complex subunit 28 Acetyltransf_1 PF00583.19 EPX70909.1 - 5.6e-12 45.5 0.0 9.1e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPX70909.1 - 3.5e-09 36.7 0.2 5.7e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPX70909.1 - 4.3e-07 30.0 0.0 5.8e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPX70909.1 - 2.6e-06 27.4 0.1 3.6e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPX70909.1 - 9.9e-06 25.2 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EPX70909.1 - 0.0051 16.6 0.0 0.0069 16.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PWI PF01480.12 EPX70910.1 - 1.3e-27 95.6 0.1 2.2e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 PWI domain Ribosomal_S13 PF00416.17 EPX70911.1 - 3e-40 136.9 3.0 3.6e-40 136.7 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EPX70911.1 - 0.00098 17.7 0.0 0.0012 17.4 0.0 1.2 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EPX70911.1 - 0.0054 16.7 0.4 0.025 14.6 0.1 2.1 2 1 0 2 2 2 1 Helix-hairpin-helix motif Peptidase_M28 PF04389.12 EPX70912.1 - 1.1e-29 103.4 0.0 1.8e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 rpo30_N PF12410.3 EPX70912.1 - 0.007 16.0 0.2 0.016 14.8 0.2 1.5 1 0 0 1 1 1 1 Poxvirus DNA dependent RNA polymerase 30kDa subunit Peptidase_M20 PF01546.23 EPX70912.1 - 0.0072 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TFIIS_C PF01096.13 EPX70913.1 - 3e-17 61.9 1.1 3e-17 61.9 0.8 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EPX70913.1 - 6.2e-17 60.9 8.1 2.4e-13 49.5 0.4 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.2 EPX70913.1 - 8.1e-06 25.5 9.2 0.0016 18.2 0.5 2.7 2 1 1 3 3 3 2 Double zinc ribbon zf-ribbon_3 PF13248.1 EPX70913.1 - 1.8e-05 23.7 9.8 0.78 9.0 0.0 3.8 3 1 0 3 3 3 3 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EPX70913.1 - 0.00016 21.0 14.8 0.28 10.7 0.8 3.5 3 1 0 3 3 3 3 zinc-ribbon domain Lar_restr_allev PF14354.1 EPX70913.1 - 0.00026 21.2 1.2 0.00026 21.2 0.9 2.8 1 1 1 2 2 2 1 Restriction alleviation protein Lar C1_1 PF00130.17 EPX70913.1 - 0.00076 19.1 5.6 0.0011 18.7 0.4 2.4 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-TFIIB PF13453.1 EPX70913.1 - 0.0019 17.3 8.3 0.002 17.2 0.6 2.3 2 0 0 2 2 2 1 Transcription factor zinc-finger Terminase_GpA PF05876.7 EPX70913.1 - 0.0019 16.6 0.4 0.0019 16.6 0.3 1.4 2 0 0 2 2 2 1 Phage terminase large subunit (GpA) zinc_ribbon_4 PF13717.1 EPX70913.1 - 0.002 17.8 9.3 5.1 6.8 0.4 4.2 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EPX70913.1 - 0.0035 16.8 9.7 4.5 6.9 0.4 4.2 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.14 EPX70913.1 - 0.004 16.8 7.9 0.24 11.0 0.2 3.0 2 1 0 2 2 2 1 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 EPX70913.1 - 0.011 15.3 8.9 0.63 9.7 0.5 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain UPF0547 PF10571.4 EPX70913.1 - 0.014 15.0 14.4 0.087 12.5 0.2 4.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 VP_N-CPKC PF11475.3 EPX70913.1 - 0.027 14.0 3.8 2.7 7.6 0.1 3.0 3 0 0 3 3 2 0 Virion protein N terminal domain Prok-RING_1 PF14446.1 EPX70913.1 - 0.027 14.1 6.1 0.92 9.2 0.3 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.1 EPX70913.1 - 0.031 13.9 2.9 1.5 8.5 0.2 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-DNA_Pol PF08996.5 EPX70913.1 - 0.034 13.5 6.2 0.04 13.2 0.7 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DUF3797 PF12677.2 EPX70913.1 - 0.061 12.9 10.6 0.58 9.8 1.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF3797) Ogr_Delta PF04606.7 EPX70913.1 - 0.062 12.9 1.4 0.062 12.9 1.0 2.9 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger Ribosomal_S27e PF01667.12 EPX70913.1 - 0.08 12.4 8.6 0.086 12.4 0.0 3.3 3 1 1 4 4 4 0 Ribosomal protein S27 Nudix_N_2 PF14803.1 EPX70913.1 - 0.081 12.6 11.1 2.7 7.7 2.4 4.1 3 1 0 3 3 3 0 Nudix N-terminal Zn_ribbon_recom PF13408.1 EPX70913.1 - 0.093 13.0 6.5 3.5 7.9 0.2 2.8 2 2 0 2 2 2 0 Recombinase zinc beta ribbon domain CNP1 PF08750.6 EPX70913.1 - 0.11 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CNP1-like family TF_Zn_Ribbon PF08271.7 EPX70913.1 - 0.12 11.6 14.5 1 8.7 3.2 3.4 3 1 0 3 3 2 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 EPX70913.1 - 0.12 12.1 11.0 0.13 12.0 1.9 3.3 2 2 1 3 3 3 0 Transposase zinc-ribbon domain DUF164 PF02591.10 EPX70913.1 - 0.13 12.0 3.1 9.2 6.1 0.0 3.7 4 0 0 4 4 4 0 Putative zinc ribbon domain zf-AN1 PF01428.11 EPX70913.1 - 0.17 11.7 9.3 3 7.7 0.8 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger DUF2387 PF09526.5 EPX70913.1 - 0.19 11.6 0.3 0.19 11.6 0.2 2.4 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zinc-ribbons_6 PF07191.7 EPX70913.1 - 0.21 11.3 9.2 0.34 10.7 0.5 2.9 2 1 1 3 3 3 0 zinc-ribbons Rubredoxin PF00301.15 EPX70913.1 - 0.22 11.4 8.3 7 6.6 0.1 3.6 4 0 0 4 4 3 0 Rubredoxin zf-FPG_IleRS PF06827.9 EPX70913.1 - 0.24 11.0 13.5 3.7 7.2 0.4 3.4 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Baculo_LEF5_C PF11792.3 EPX70913.1 - 0.26 10.6 7.6 0.6 9.5 0.0 3.7 4 0 0 4 4 4 0 Baculoviridae late expression factor 5 C-terminal domain zf-C2H2_4 PF13894.1 EPX70913.1 - 0.28 11.6 12.9 0.7 10.3 0.9 3.8 4 0 0 4 4 3 0 C2H2-type zinc finger zf-MYND PF01753.13 EPX70913.1 - 0.3 10.9 7.9 1 9.3 1.2 2.7 2 1 0 2 2 2 0 MYND finger YhfH PF14149.1 EPX70913.1 - 0.33 10.7 9.5 3.2 7.6 0.9 3.3 3 0 0 3 3 3 0 YhfH-like protein zf-ISL3 PF14690.1 EPX70913.1 - 0.36 10.8 8.5 4.4 7.4 0.1 3.7 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PolC_DP2 PF03833.8 EPX70913.1 - 0.41 8.2 6.0 0.22 9.1 0.4 2.0 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 GFA PF04828.9 EPX70913.1 - 0.47 10.4 10.3 1.6 8.7 0.6 3.4 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.11 EPX70913.1 - 0.49 10.2 6.8 1.1 9.2 1.2 2.9 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RecR PF02132.10 EPX70913.1 - 0.67 9.4 13.2 0.2 11.1 2.0 3.5 3 1 0 3 3 3 0 RecR protein Zn-ribbon_8 PF09723.5 EPX70913.1 - 0.73 9.8 17.3 3.7 7.5 0.4 3.8 2 2 1 4 4 4 0 Zinc ribbon domain DUF2072 PF09845.4 EPX70913.1 - 0.74 9.7 7.0 2 8.3 0.1 3.1 1 1 2 3 3 3 0 Zn-ribbon containing protein (DUF2072) zf-RING_3 PF14369.1 EPX70913.1 - 0.82 9.7 9.3 9.3 6.3 0.0 3.7 3 1 0 3 3 3 0 zinc-finger Nop10p PF04135.7 EPX70913.1 - 0.87 9.3 0.1 0.87 9.3 0.1 2.8 3 1 1 4 4 3 0 Nucleolar RNA-binding protein, Nop10p family RNHCP PF12647.2 EPX70913.1 - 0.9 9.4 6.2 2.5 7.9 1.9 2.7 1 1 1 2 2 2 0 RNHCP domain DUF2082 PF09855.4 EPX70913.1 - 0.96 9.3 0.1 0.96 9.3 0.0 3.5 3 1 0 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) IBR PF01485.16 EPX70913.1 - 1 9.2 10.9 0.75 9.7 0.9 2.6 2 2 0 2 2 2 0 IBR domain zf-LITAF-like PF10601.4 EPX70913.1 - 1.2 9.0 9.5 5.2 7.0 0.1 4.0 3 1 1 4 4 4 0 LITAF-like zinc ribbon domain zf-C4_Topoisom PF01396.14 EPX70913.1 - 1.3 8.5 15.6 0.35 10.4 1.1 4.0 3 1 1 4 4 4 0 Topoisomerase DNA binding C4 zinc finger Stc1 PF12898.2 EPX70913.1 - 1.5 8.9 7.0 0.7 9.9 0.5 2.2 1 1 1 2 2 2 0 Stc1 domain PhnA_Zn_Ribbon PF08274.7 EPX70913.1 - 2.4 7.9 11.6 31 4.4 2.1 4.0 3 1 0 3 3 3 0 PhnA Zinc-Ribbon zf-C4pol PF14260.1 EPX70913.1 - 2.5 8.1 7.5 46 4.0 4.2 2.6 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zf-CHY PF05495.7 EPX70913.1 - 3 8.0 9.1 4.4 7.5 0.3 2.8 2 1 0 2 2 2 0 CHY zinc finger zf-C2H2 PF00096.21 EPX70913.1 - 3.2 8.2 15.1 0.58 10.6 0.8 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2HC5 PF06221.8 EPX70913.1 - 3.3 7.5 8.2 7.6 6.3 0.3 2.9 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type DUF2296 PF10058.4 EPX70913.1 - 3.6 7.3 7.2 14 5.5 0.0 3.4 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) zf-C2H2_6 PF13912.1 EPX70913.1 - 3.8 7.5 17.1 0.61 10.0 0.3 4.2 4 1 0 4 4 4 0 C2H2-type zinc finger PADR1 PF08063.7 EPX70913.1 - 4.4 6.7 10.6 2.5 7.5 0.1 3.4 3 1 0 3 3 3 0 PADR1 (NUC008) domain CpXC PF14353.1 EPX70913.1 - 4.5 7.2 10.9 10 6.1 1.7 3.4 2 2 1 3 3 3 0 CpXC protein RRN7 PF11781.3 EPX70913.1 - 5.5 6.5 10.7 31 4.1 0.1 3.9 3 1 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 C1_4 PF07975.7 EPX70913.1 - 5.7 7.0 12.4 11 6.0 1.6 3.3 2 2 0 2 2 2 0 TFIIH C1-like domain NOB1_Zn_bind PF08772.6 EPX70913.1 - 6 6.7 13.3 3.2 7.6 0.1 3.6 2 2 2 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like ADK_lid PF05191.9 EPX70913.1 - 6.1 6.6 8.5 36 4.1 0.0 3.7 4 0 0 4 4 4 0 Adenylate kinase, active site lid Opy2 PF09463.5 EPX70913.1 - 7.1 6.8 12.9 22 5.2 0.0 3.5 3 1 0 3 3 3 0 Opy2 protein Elf1 PF05129.8 EPX70913.1 - 8.2 6.2 9.0 0.51 10.0 0.7 2.7 2 2 0 2 2 2 0 Transcription elongation factor Elf1 like Ino80_Iec3 PF14612.1 EPX70914.1 - 3.4e-11 43.6 0.4 6.1e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Osmo_CC PF08946.5 EPX70914.1 - 0.09 12.8 0.2 0.09 12.8 0.1 1.8 2 0 0 2 2 2 0 Osmosensory transporter coiled coil TAF8_C PF10406.4 EPX70916.1 - 2.2e-18 66.0 1.3 3.6e-18 65.3 0.9 1.3 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Phage_CP76 PF06892.6 EPX70916.1 - 0.0074 15.6 0.1 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Phage regulatory protein CII (CP76) Methyltransf_22 PF13383.1 EPX70916.1 - 0.055 12.9 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mitochondr_Som1 PF11093.3 EPX70917.1 - 0.018 14.8 0.1 0.018 14.8 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial export protein Som1 Rxt3 PF08642.5 EPX70918.1 - 1.2e-22 80.2 3.2 2.2e-14 53.6 0.0 3.1 2 1 1 3 3 3 2 Histone deacetylation protein Rxt3 LCCL PF03815.14 EPX70918.1 - 0.00081 19.3 0.0 0.0027 17.6 0.0 1.8 2 0 0 2 2 2 1 LCCL domain DUF2457 PF10446.4 EPX70919.1 - 6.3e-17 61.4 7.1 6.3e-17 61.4 4.9 3.2 1 1 2 3 3 3 1 Protein of unknown function (DUF2457) LAP1C PF05609.7 EPX70919.1 - 4.1 5.9 15.2 0.052 12.2 5.2 1.7 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Biotin_lipoyl PF00364.17 EPX70920.1 - 1.2e-21 76.0 0.7 2.5e-21 75.0 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EPX70920.1 - 4.5e-05 22.9 0.1 0.00014 21.3 0.0 1.9 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EPX70920.1 - 0.00029 20.4 0.6 0.0086 15.7 0.0 2.9 2 1 1 3 3 3 1 Biotin-lipoyl like QRPTase_N PF02749.11 EPX70920.1 - 0.16 11.8 0.1 0.72 9.7 0.0 2.1 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Peptidase_M22 PF00814.20 EPX70921.1 - 7.5e-69 232.2 0.0 8.9e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family RabGAP-TBC PF00566.13 EPX70922.1 - 8e-43 146.3 2.9 8e-43 146.3 2.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.15 EPX70922.1 - 1.3e-10 40.6 0.5 3.8e-10 39.1 0.3 1.7 1 0 0 1 1 1 1 GRAM domain SPRY PF00622.23 EPX70923.1 - 4.3e-29 101.1 1.0 6.9e-29 100.4 0.7 1.3 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 EPX70923.1 - 3.5e-16 59.2 2.8 3.5e-16 59.2 2.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EPX70923.1 - 0.0013 18.4 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 LisH TnpV PF14198.1 EPX70923.1 - 0.012 15.4 0.6 0.39 10.6 0.0 2.8 2 1 1 3 3 3 0 Transposon-encoded protein TnpV Blo-t-5 PF11642.3 EPX70923.1 - 0.06 13.0 1.0 0.57 9.9 0.2 2.2 2 0 0 2 2 2 0 Mite allergen Blo t 5 UQ_con PF00179.21 EPX70924.1 - 2.6e-48 162.9 0.0 3.5e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EPX70924.1 - 4.4e-05 23.1 0.1 7.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EPX70924.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.6 1 1 0 1 1 1 0 RWD domain Pkinase PF00069.20 EPX70925.1 - 3.4e-66 223.0 0.0 4.5e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70925.1 - 9.5e-25 87.1 0.0 1.5e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX70925.1 - 2e-06 26.9 0.0 3.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPX70925.1 - 0.003 16.6 0.0 0.0053 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX70925.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DFP PF04127.10 EPX70926.1 - 4.9e-21 75.1 0.0 3.4e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Cmc1 PF08583.5 EPX70927.1 - 2.8e-13 49.4 4.8 4e-13 48.9 3.3 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EPX70927.1 - 0.04 13.9 2.0 0.48 10.4 0.2 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF4239 PF14023.1 EPX70927.1 - 0.073 12.4 0.4 0.089 12.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) UCR_hinge PF02320.11 EPX70927.1 - 0.24 11.3 3.8 0.14 12.0 0.6 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.8 EPX70927.1 - 1.2 9.1 4.4 4.4 7.3 0.4 2.6 2 0 0 2 2 2 0 CHCH domain DUF3128 PF11326.3 EPX70927.1 - 1.3 9.2 6.1 6.6 6.9 4.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Ubiq_cyt_C_chap PF03981.7 EPX70928.1 - 1.6e-33 115.5 0.2 2.2e-33 115.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone TIP41 PF04176.8 EPX70929.1 - 1.1e-55 187.6 0.1 1.4e-55 187.4 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family PH_7 PF15408.1 EPX70930.1 - 4.8e-23 81.0 0.0 9.7e-23 80.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EPX70930.1 - 0.00015 21.9 0.0 0.00053 20.1 0.0 2.0 1 0 0 1 1 1 1 PH domain PRCC PF10253.4 EPX70931.1 - 3.2e-12 47.5 4.2 3.2e-12 47.5 2.9 2.9 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting MatE PF01554.13 EPX70932.1 - 1.7e-61 206.5 27.4 9.2e-33 113.1 8.8 2.5 2 0 0 2 2 2 2 MatE DUF3446 PF11928.3 EPX70932.1 - 5.2 7.3 10.8 7.4 6.8 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) SET PF00856.23 EPX70933.1 - 1e-09 38.9 2.9 5.8e-08 33.2 0.1 3.0 2 2 0 2 2 2 1 SET domain DUF3908 PF13048.1 EPX70933.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3908) BolA PF01722.13 EPX70934.1 - 5.7e-15 55.0 0.0 7.7e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Ins_P5_2-kin PF06090.7 EPX70935.1 - 2.6e-39 135.1 0.3 2e-38 132.1 0.2 2.4 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase PRESAN PF09687.5 EPX70935.1 - 0.052 13.6 0.4 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 Plasmodium RESA N-terminal Ribosomal_L12 PF00542.14 EPX70936.1 - 6.4e-21 74.1 9.5 1.1e-19 70.1 3.3 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EPX70936.1 - 0.43 11.0 11.8 0.056 13.8 4.0 2.2 2 1 0 2 2 2 0 60s Acidic ribosomal protein CTK3 PF12243.3 EPX70937.1 - 1.2e-49 167.5 0.0 1.8e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EPX70937.1 - 1.1e-16 60.6 3.1 1.1e-16 60.6 2.1 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Nro1 PF12753.2 EPX70938.1 - 2.6e-66 224.2 4.3 1e-64 218.9 3.0 2.0 1 1 0 1 1 1 1 Nuclear pore complex subunit Nro1 URO-D PF01208.12 EPX70939.1 - 1.5e-130 435.1 0.0 1.7e-130 434.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) cNMP_binding PF00027.24 EPX70940.1 - 7.5e-36 121.8 0.0 1e-16 60.5 0.0 4.5 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EPX70940.1 - 3.3e-18 66.3 5.5 3.5e-17 63.0 3.8 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase DUF21 PF01595.15 EPX70941.1 - 5.3e-33 113.8 0.1 8.7e-33 113.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EPX70941.1 - 0.0073 16.0 0.1 0.15 11.8 0.0 2.7 2 1 0 2 2 2 1 CBS domain Got1 PF04178.7 EPX70942.1 - 1.7e-18 66.8 12.9 1.9e-18 66.6 9.0 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 EPX70942.1 - 0.31 9.9 7.7 0.37 9.7 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) CAAD PF14159.1 EPX70942.1 - 1.6 8.4 8.4 1.9 8.2 0.6 2.3 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Neurensin PF14927.1 EPX70942.1 - 6.2 6.1 6.1 12 5.2 4.2 1.7 1 1 0 1 1 1 0 Neurensin NfeD PF01957.13 EPX70942.1 - 8.5 6.5 7.6 9.3 6.3 4.4 1.7 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Rhodanese PF00581.15 EPX70943.1 - 1.3e-27 96.3 0.0 5e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain efThoc1 PF11957.3 EPX70944.1 - 8.3e-97 324.7 0.1 8.3e-97 324.7 0.1 1.8 3 0 0 3 3 3 1 THO complex subunit 1 transcription elongation factor SNF2_N PF00176.18 EPX70945.1 - 4.3e-75 252.2 0.0 9.1e-75 251.2 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPX70945.1 - 2e-13 50.0 0.0 6.1e-13 48.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPX70945.1 - 0.00012 21.5 0.0 0.0026 17.2 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Seryl_tRNA_N PF02403.17 EPX70945.1 - 0.039 13.9 0.2 0.039 13.9 0.2 3.6 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CHCH PF06747.8 EPX70946.1 - 1e-07 31.6 7.0 1.5e-07 31.1 4.8 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EPX70946.1 - 0.26 11.4 3.4 0.3 11.2 2.3 1.3 1 0 0 1 1 1 0 GCK domain RRM_5 PF13893.1 EPX70947.1 - 1.5e-06 27.9 0.0 3.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX70947.1 - 2.1e-05 24.0 0.0 4.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPX70947.1 - 0.0004 20.0 0.0 0.00077 19.1 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 EPX70947.1 - 0.0051 16.7 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DSHCT PF08148.7 EPX70948.1 - 2.5e-56 189.7 0.3 6e-56 188.5 0.2 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EPX70948.1 - 4.3e-21 75.1 1.0 1.7e-20 73.2 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX70948.1 - 1.5e-05 24.7 0.0 4.2e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EPX70948.1 - 0.0055 15.9 1.0 0.042 13.0 0.7 2.4 1 1 0 1 1 1 1 rRNA-processing arch domain GPI2 PF06432.6 EPX70949.1 - 1.1e-91 307.1 23.7 1.2e-91 306.9 16.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase SMC_Nse1 PF07574.8 EPX70950.1 - 2.7e-14 53.2 0.0 2e-11 43.8 0.0 2.2 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex Mga PF05043.8 EPX70950.1 - 0.0031 17.7 0.1 0.0063 16.7 0.1 1.5 1 0 0 1 1 1 1 Mga helix-turn-helix domain zf-RING-like PF08746.6 EPX70950.1 - 0.075 13.0 15.2 0.18 11.8 10.5 1.6 1 1 0 1 1 1 0 RING-like domain Cpn10 PF00166.16 EPX70951.1 - 2.9e-24 84.8 0.0 3.3e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Amidase PF01425.16 EPX70952.1 - 3.4e-107 359.0 0.0 4.3e-107 358.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Acetyltransf_7 PF13508.1 EPX70953.1 - 2.7e-07 30.6 0.1 6.6e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPX70953.1 - 0.00019 21.3 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EPX70953.1 - 0.00067 19.5 0.0 0.0024 17.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPX70953.1 - 0.00071 19.6 0.0 0.0025 17.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Pex24p PF06398.6 EPX70954.1 - 4.5e-36 124.3 5.9 1.2e-34 119.7 4.1 2.1 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Aldedh PF00171.17 EPX70955.1 - 4.5e-157 523.1 0.0 5.5e-157 522.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPX70955.1 - 0.16 10.6 0.2 1.5 7.4 0.2 2.0 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) IBN_N PF03810.14 EPX70956.1 - 1.6e-19 69.5 2.2 1.5e-18 66.4 0.4 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.5 EPX70956.1 - 4.8e-10 38.5 0.0 2.7e-08 32.7 0.0 2.7 2 0 0 2 2 2 1 Cse1 HEAT_2 PF13646.1 EPX70956.1 - 0.00071 19.8 0.4 2.7 8.3 0.1 3.3 2 0 0 2 2 2 2 HEAT repeats DUF2435 PF10363.4 EPX70956.1 - 0.038 13.8 0.6 0.21 11.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) DUF2150 PF09920.4 EPX70956.1 - 0.055 13.0 0.7 0.16 11.5 0.5 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) HEAT PF02985.17 EPX70956.1 - 0.067 13.2 2.8 0.19 11.8 0.1 3.5 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 EPX70956.1 - 0.19 12.2 2.8 2.1 8.9 0.1 4.0 3 1 1 4 4 4 0 HEAT-like repeat Actin PF00022.14 EPX70957.1 - 2.9e-78 263.0 0.0 3.4e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Actin Dfp1_Him1_M PF08630.5 EPX70958.1 - 2.7e-40 137.0 0.0 8.4e-40 135.4 0.0 1.9 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 EPX70958.1 - 1.3e-22 79.1 0.9 2.4e-22 78.3 0.6 1.5 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EPX70958.1 - 1.1e-06 28.7 0.1 3.2e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EPX70958.1 - 0.00015 21.5 0.0 0.00036 20.3 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain zf-C2H2_2 PF12756.2 EPX70958.1 - 0.026 14.6 0.3 0.064 13.3 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) KH_1 PF00013.24 EPX70959.1 - 1.2e-100 329.0 51.0 1.9e-11 43.4 0.1 15.5 14 2 0 14 14 14 13 KH domain KH_3 PF13014.1 EPX70959.1 - 8.5e-64 210.3 40.9 4.5e-08 32.5 0.1 14.5 14 0 0 14 14 14 9 KH domain KH_2 PF07650.12 EPX70959.1 - 1e-07 31.3 35.4 0.13 11.8 0.9 10.6 9 2 2 11 11 11 4 KH domain BMC PF00936.14 EPX70959.1 - 2.8e-06 26.9 8.3 0.36 10.5 0.0 7.1 9 0 0 9 9 9 2 BMC domain FCD PF07729.7 EPX70959.1 - 0.0014 18.9 0.0 0.23 11.7 0.0 3.4 3 0 0 3 3 3 1 FCD domain SLBB PF10531.4 EPX70959.1 - 0.075 12.9 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 SLBB domain Seryl_tRNA_N PF02403.17 EPX70959.1 - 0.61 10.1 9.1 0.64 10.0 0.1 4.3 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain zf-C2H2_2 PF12756.2 EPX70960.1 - 5.4e-36 122.7 13.8 1.7e-30 105.1 0.5 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EPX70960.1 - 1.1e-11 44.4 28.4 1.6e-05 24.9 2.0 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPX70960.1 - 2.2e-08 34.0 10.3 5.5e-07 29.5 1.7 4.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EPX70960.1 - 0.00027 21.0 30.5 0.025 14.9 0.6 5.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type DUF629 PF04780.7 EPX70960.1 - 0.00033 19.3 9.2 0.0017 16.9 0.0 3.6 2 1 1 4 4 4 2 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 EPX70960.1 - 0.0048 16.7 0.9 0.0048 16.7 0.6 4.5 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EPX70960.1 - 0.022 15.0 25.2 0.17 12.2 0.4 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger Pal1 PF08316.6 EPX70960.1 - 0.072 13.5 1.8 0.17 12.3 0.1 2.4 2 0 0 2 2 2 0 Pal1 cell morphology protein zf-LYAR PF08790.6 EPX70960.1 - 0.22 11.2 0.1 0.22 11.2 0.1 4.4 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger AKAP95 PF04988.7 EPX70960.1 - 6.3 6.5 11.8 9.3 5.9 1.1 3.4 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2HC5 PF06221.8 EPX70960.1 - 9.6 6.0 8.4 2.4 7.9 0.1 3.3 4 0 0 4 4 4 0 Putative zinc finger motif, C2HC5-type STAG PF08514.6 EPX70961.1 - 4.9e-05 23.0 0.0 0.00025 20.7 0.0 2.3 1 0 0 1 1 1 1 STAG domain Flu_M1_C PF08289.6 EPX70961.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Cyclin_N PF00134.18 EPX70962.1 - 2.7e-36 123.9 0.1 4.9e-36 123.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPX70962.1 - 1.1e-28 99.4 0.1 2.7e-28 98.2 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain PGP_phosphatase PF09419.5 EPX70963.1 - 6.8e-54 181.7 0.0 7.9e-54 181.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EPX70963.1 - 0.00022 20.8 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Fe-S_biosyn PF01521.15 EPX70964.1 - 1.3e-19 70.1 0.0 1.8e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis MCP_N PF05581.7 EPX70964.1 - 0.017 15.2 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Vibrio chemotaxis protein N terminus MAGE PF01454.14 EPX70965.1 - 9.1e-26 90.4 0.0 1.2e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 MAGE family Myosin_head PF00063.16 EPX70966.1 - 9e-252 837.0 3.6 9e-252 837.0 2.5 1.9 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.14 EPX70966.1 - 2e-07 30.5 0.6 6.6e-07 28.8 0.4 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ERM PF00769.14 EPX70966.1 - 2.2e-05 24.1 31.8 2.2e-05 24.1 22.0 5.2 2 1 1 5 5 5 2 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 EPX70966.1 - 0.0042 16.3 9.0 0.0042 16.3 6.3 4.7 1 1 4 5 5 5 1 Reovirus sigma C capsid protein HALZ PF02183.13 EPX70966.1 - 0.006 16.2 1.0 0.006 16.2 0.7 10.1 10 1 1 11 11 11 1 Homeobox associated leucine zipper AAA_22 PF13401.1 EPX70966.1 - 0.012 15.8 0.8 0.16 12.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EPX70966.1 - 0.048 13.4 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain BLOC1_2 PF10046.4 EPX70966.1 - 0.24 11.5 0.0 0.24 11.5 0.0 8.8 5 2 2 9 9 9 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CNH PF00780.17 EPX70967.1 - 9.1e-44 149.9 0.0 1.6e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EPX70967.1 - 1.4e-33 116.2 0.1 2.4e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EPX70967.1 - 3.5e-16 59.3 0.0 9.8e-16 57.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EPX70967.1 - 1.2e-05 25.4 0.3 6e-05 23.2 0.1 2.4 2 1 0 2 2 2 1 PH domain CNH PF00780.17 EPX70968.1 - 7.1e-83 278.1 0.0 1.2e-82 277.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EPX70968.1 - 1.4e-36 125.4 0.9 3.6e-36 124.0 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.15 EPX70968.1 - 1.9e-32 112.5 0.0 3.9e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EPX70968.1 - 3.1e-11 42.8 0.2 7.6e-11 41.6 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SNase PF00565.12 EPX70969.1 - 5.2e-58 193.9 0.0 2.3e-15 56.7 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EPX70969.1 - 1.8e-23 82.6 0.0 4e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Ribosomal_L37 PF08561.5 EPX70970.1 - 3.4e-19 68.2 7.0 7.7e-18 63.8 2.3 2.9 2 1 0 2 2 2 1 Mitochondrial ribosomal protein L37 PolyA_pol PF01743.15 EPX70971.1 - 9.7e-21 74.2 0.1 1.8e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EPX70971.1 - 5.1e-06 25.9 0.0 1.8e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A MU117 PF15474.1 EPX70972.1 - 2.1e-24 85.8 7.2 2.7e-24 85.4 5.0 1.1 1 0 0 1 1 1 1 Meiotically up-regulated gene family PolC_DP2 PF03833.8 EPX70973.1 - 0.13 9.8 1.2 0.18 9.4 0.8 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 TFIIS_M PF07500.9 EPX70974.1 - 4.6e-23 81.4 0.3 8.6e-23 80.5 0.2 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EPX70974.1 - 2.8e-13 50.3 0.0 5.8e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EPX70974.1 - 4e-09 36.0 10.5 6.9e-09 35.2 7.3 1.4 1 0 0 1 1 1 1 PHD-finger LETM1 PF07766.8 EPX70974.1 - 0.0046 16.0 0.3 0.0078 15.2 0.2 1.3 1 0 0 1 1 1 1 LETM1-like protein zf-CW PF07496.10 EPX70974.1 - 0.047 13.4 5.1 0.1 12.3 3.5 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.1 EPX70974.1 - 0.11 11.8 6.2 0.19 11.0 4.3 1.4 1 0 0 1 1 1 0 PHD-finger TPR_11 PF13414.1 EPX70975.1 - 7.8e-53 176.0 28.8 1.9e-18 65.8 1.8 6.4 5 1 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 EPX70975.1 - 1.9e-39 131.7 28.9 1.1e-06 28.0 0.6 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EPX70975.1 - 4.9e-32 107.2 28.4 1.8e-05 24.3 0.3 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 EPX70975.1 - 3.2e-19 68.6 15.5 7e-10 38.7 2.1 6.1 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPX70975.1 - 1e-16 61.0 11.8 0.0011 19.2 0.3 6.9 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPX70975.1 - 3.2e-15 56.3 20.4 0.00052 20.6 0.0 6.9 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EPX70975.1 - 8.1e-15 53.9 13.4 0.19 12.4 0.0 7.9 6 2 3 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EPX70975.1 - 3.7e-13 48.2 23.4 0.012 15.2 0.0 8.5 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 EPX70975.1 - 8.2e-12 44.3 14.1 0.004 17.2 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPX70975.1 - 1.4e-08 33.8 8.9 6.5e-05 22.4 0.0 6.0 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPX70975.1 - 4.6e-08 32.8 2.4 0.73 9.7 0.0 5.3 2 2 3 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 EPX70975.1 - 0.00021 21.3 17.7 0.086 12.9 0.9 4.7 2 1 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 EPX70975.1 - 0.0013 18.1 8.3 0.47 9.8 0.2 4.5 2 2 2 4 4 4 2 26S proteasome subunit RPN7 TPR_10 PF13374.1 EPX70975.1 - 0.0074 16.1 6.5 1.3 9.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.7 EPX70975.1 - 0.0085 15.8 5.4 0.45 10.3 0.7 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPX70975.1 - 0.026 14.9 19.7 0.4 11.2 0.0 7.0 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF3808 PF10300.4 EPX70975.1 - 1.2 7.6 5.9 0.59 8.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) TPR_4 PF07721.9 EPX70975.1 - 8.7 7.1 7.9 22 5.8 0.2 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Oxysterol_BP PF01237.13 EPX70976.1 - 1.3e-86 290.3 0.0 1.6e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Alb1 PF09135.6 EPX70977.1 - 7.1e-07 29.8 20.2 8.3e-07 29.6 14.0 1.1 1 0 0 1 1 1 1 Alb1 DUF1974 PF09317.6 EPX70977.1 - 0.11 11.8 3.9 0.14 11.5 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) MDFI PF15316.1 EPX70977.1 - 4.7 7.1 5.6 5.5 6.9 3.9 1.2 1 0 0 1 1 1 0 MyoD family inhibitor PI3_PI4_kinase PF00454.22 EPX70978.1 - 1.5e-41 142.4 1.3 2.6e-41 141.6 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EPX70978.1 - 7.7e-26 90.6 1.6 2.4e-25 89.0 0.2 2.6 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FAT PF02259.18 EPX70978.1 - 3.1e-08 33.0 3.8 3.6e-07 29.4 1.7 2.6 2 0 0 2 2 2 1 FAT domain FATC PF02260.15 EPX70978.1 - 1.2e-05 24.6 0.0 3.4e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 FATC domain CRAL_TRIO PF00650.15 EPX70979.1 - 4.2e-39 133.5 0.0 6.3e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPX70979.1 - 1.6e-10 40.9 0.3 4.1e-10 39.6 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPX70979.1 - 0.0038 17.1 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Rep_fac-A_3 PF08661.6 EPX70980.1 - 3.8e-25 87.9 0.1 4.5e-25 87.6 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 RNB PF00773.14 EPX70981.1 - 9.5e-57 192.7 0.1 2.3e-56 191.4 0.0 1.7 1 0 0 1 1 1 1 RNB domain TRP PF06011.7 EPX70983.1 - 2.8e-57 194.2 31.8 9.7e-57 192.4 22.1 1.7 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPX70983.1 - 6.3e-13 48.9 0.0 1.2e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 ML-like domain DUF1469 PF07332.6 EPX70983.1 - 0.66 9.7 5.0 0.1 12.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) UDPGP PF01704.13 EPX70984.1 - 2.3e-192 639.1 2.1 2.7e-192 638.9 1.5 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Peptidase_M1 PF01433.15 EPX70985.1 - 8.7e-78 262.1 0.0 1.1e-77 261.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EPX70985.1 - 7.2e-48 161.8 0.7 1.3e-47 160.9 0.2 1.7 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EPX70985.1 - 5e-14 52.4 0.0 9.3e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EPX70985.1 - 0.11 12.4 0.6 0.71 9.8 0.4 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase IBN_N PF03810.14 EPX70986.1 - 5.8e-14 51.7 1.1 1.4e-13 50.5 0.1 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EPX70986.1 - 4.4e-07 29.9 0.6 4.4e-07 29.9 0.4 4.3 4 1 1 5 5 5 1 Exportin 1-like protein RIH_assoc PF08454.6 EPX70986.1 - 0.053 13.1 0.3 0.25 10.9 0.0 2.2 2 0 0 2 2 2 0 RyR and IP3R Homology associated Pkinase PF00069.20 EPX70987.1 - 4.7e-66 222.5 0.0 6.4e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70987.1 - 2.5e-27 95.6 0.0 5.6e-27 94.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX70987.1 - 0.00011 21.2 1.3 0.15 10.9 0.1 2.5 2 1 0 2 2 2 2 Kinase-like DUF2413 PF10310.4 EPX70988.1 - 3.4e-85 286.5 15.9 4.6e-85 286.0 11.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) FTP PF07504.8 EPX70988.1 - 0.058 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif GPI-anchored PF10342.4 EPX70989.1 - 1e-10 41.9 4.8 1e-10 41.9 3.4 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EPX70989.1 - 0.087 12.3 2.8 0.29 10.6 1.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) DUF605 PF04652.11 EPX70989.1 - 1.7 7.9 20.9 2.2 7.6 14.5 1.2 1 0 0 1 1 1 0 Vta1 like Ribosomal_L14 PF00238.14 EPX70990.1 - 5e-35 119.9 0.0 5.6e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Mad3_BUB1_I PF08311.7 EPX70991.1 - 1.2e-31 109.0 0.5 2.3e-31 108.2 0.4 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EPX70991.1 - 2.5e-13 49.7 0.0 4.9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX70991.1 - 5.4e-06 25.6 0.0 9.5e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WTF PF03303.8 EPX70992.1 - 0.16 11.3 8.4 1.1 8.5 5.8 2.1 1 1 0 1 1 1 0 WTF protein ELFV_dehydrog PF00208.16 EPX70993.1 - 5.9e-60 202.8 0.0 9.1e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EPX70993.1 - 2.8e-15 54.9 0.1 1.2e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EPX70993.1 - 2.5e-05 23.8 0.0 8.4e-05 22.1 0.0 1.9 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ku_PK_bind PF08785.6 EPX70993.1 - 0.031 14.1 2.0 0.77 9.6 0.2 2.7 2 0 0 2 2 2 0 Ku C terminal domain like SIR2 PF02146.12 EPX70994.1 - 4.4e-55 186.1 0.0 8.3e-55 185.2 0.0 1.5 1 0 0 1 1 1 1 Sir2 family Vfa1 PF08432.5 EPX70994.1 - 0.13 12.2 9.4 0.22 11.5 6.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FbpA PF05833.6 EPX70995.1 - 5.1e-36 124.1 10.2 5.1e-36 124.1 7.1 3.4 2 2 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 EPX70995.1 - 5.9e-20 70.9 0.0 2e-19 69.2 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 EPX70995.1 - 2.4e-18 65.8 0.0 6.8e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Band_7 PF01145.20 EPX70996.1 - 1.3e-21 77.3 0.3 1.8e-21 76.8 0.2 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ribosomal_L34e PF01199.13 EPX70997.1 - 2e-38 130.4 0.9 2.6e-38 130.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e VTC PF09359.5 EPX70998.1 - 4e-100 334.4 1.0 4.2e-100 334.4 0.0 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EPX70998.1 - 7.7e-27 94.7 18.0 4e-12 46.4 7.5 4.1 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EPX70998.1 - 1.6e-08 34.6 3.3 3.4e-08 33.5 2.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) AIRC PF00731.15 EPX70999.1 - 3.5e-66 221.1 1.9 6.8e-66 220.1 1.3 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EPX70999.1 - 3.6e-66 221.7 0.0 5.8e-66 221.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EPX70999.1 - 4.9e-12 45.9 0.0 9.5e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EPX70999.1 - 5.8e-05 22.4 0.0 0.00011 21.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 EPX70999.1 - 8.2e-05 22.0 0.0 0.00027 20.3 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EPX70999.1 - 0.013 14.2 0.0 1 8.0 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon XdhC_C PF13478.1 EPX70999.1 - 0.019 15.2 0.0 0.054 13.8 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain CoA_binding_2 PF13380.1 EPX70999.1 - 0.075 13.2 0.3 14 5.8 0.0 2.8 1 1 1 2 2 2 0 CoA binding domain MerC PF03203.9 EPX71000.1 - 0.78 10.1 4.0 1.9 8.9 2.7 1.6 1 1 0 1 1 1 0 MerC mercury resistance protein Aconitase PF00330.15 EPX71001.1 - 1.1e-154 515.4 0.0 2.6e-154 514.1 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPX71001.1 - 1.1e-38 132.2 0.0 2.2e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L21p PF00829.16 EPX71001.1 - 6.9e-10 38.9 0.1 1.3e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF521 PF04412.8 EPX71001.1 - 0.0085 14.6 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Abhydrolase_6 PF12697.2 EPX71003.1 - 1.3e-23 84.0 0.0 1.7e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPX71003.1 - 8.8e-13 48.3 0.0 1.7e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPX71003.1 - 1.4e-09 37.8 0.0 1.7e-09 37.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EPX71003.1 - 0.00071 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EPX71003.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 EPX71003.1 - 0.0051 15.9 0.0 0.21 10.6 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.9 EPX71003.1 - 0.0076 15.5 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EPX71003.1 - 0.044 13.3 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Ser_hydrolase PF06821.8 EPX71003.1 - 0.061 12.9 0.0 0.48 10.0 0.0 2.3 1 1 2 3 3 3 0 Serine hydrolase DUF2305 PF10230.4 EPX71003.1 - 0.077 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 EPX71003.1 - 0.091 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.16 EPX71003.1 - 0.12 11.5 0.0 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Calreticulin PF00262.13 EPX71005.1 - 1.3e-21 76.6 0.2 2.1e-21 76.0 0.0 1.3 2 0 0 2 2 2 1 Calreticulin family Glyco_hydro_114 PF03537.8 EPX71005.1 - 0.053 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 DcpS_C PF11969.3 EPX71006.1 - 5e-27 94.4 1.7 1e-26 93.4 1.2 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EPX71006.1 - 8.9e-27 93.6 2.1 1.4e-26 93.0 0.9 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Sld5 PF05916.6 EPX71007.1 - 3.6e-06 27.2 0.2 1.1e-05 25.6 0.1 2.0 1 1 0 1 1 1 1 GINS complex protein UPF0086 PF01868.11 EPX71008.1 - 3.4e-15 55.4 0.0 5.4e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Arm PF00514.18 EPX71010.1 - 1.1e-05 25.0 0.4 0.00032 20.4 0.0 3.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EPX71010.1 - 0.0084 16.3 1.4 0.85 9.9 0.2 4.0 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 EPX71010.1 - 0.22 12.0 5.7 0.24 11.9 0.1 4.1 5 0 0 5 5 5 0 HEAT-like repeat DNA_mis_repair PF01119.14 EPX71011.1 - 8.4e-25 86.5 0.1 1.5e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EPX71011.1 - 5.1e-14 52.0 0.0 1.4e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EPX71011.1 - 1.6e-10 40.6 0.0 5.2e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RIO1 PF01163.17 EPX71012.1 - 6.1e-52 175.7 0.1 1.1e-51 174.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EPX71012.1 - 2.4e-31 107.6 0.1 4.4e-31 106.8 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EPX71012.1 - 3.6e-14 53.0 0.8 1.2e-06 28.4 0.0 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EPX71012.1 - 6e-06 25.4 0.0 0.00041 19.4 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EPX71012.1 - 0.00038 19.6 0.1 0.00073 18.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain F-box-like PF12937.2 EPX71013.1 - 3.5e-12 45.8 1.9 6.8e-12 44.9 1.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPX71013.1 - 4.1e-08 32.6 1.0 9.8e-08 31.4 0.7 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EPX71013.1 - 0.00013 21.6 0.3 0.039 13.8 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat UIM PF02809.15 EPX71013.1 - 0.0045 16.4 11.0 0.0079 15.6 0.4 2.8 2 0 0 2 2 2 1 Ubiquitin interaction motif F-box-like_2 PF13013.1 EPX71013.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain Citrate_synt PF00285.16 EPX71014.1 - 5.3e-15 55.0 0.0 4.3e-14 52.0 0.0 2.1 1 1 0 1 1 1 1 Citrate synthase CoA_binding PF02629.14 EPX71014.1 - 1e-14 54.7 0.0 2.7e-14 53.4 0.0 1.8 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EPX71014.1 - 4.9e-14 52.2 0.0 8.5e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EPX71014.1 - 2e-07 30.6 0.0 3.2e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain 5-FTHF_cyc-lig PF01812.15 EPX71015.1 - 2.2e-39 135.1 0.0 2.6e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Na_H_antiport_1 PF06965.7 EPX71015.1 - 0.15 10.7 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Na+/H+ antiporter 1 Strep_SA_rep PF06696.6 EPX71016.1 - 0.054 13.2 0.3 0.088 12.5 0.2 1.3 1 0 0 1 1 1 0 Streptococcal surface antigen repeat B-block_TFIIIC PF04182.7 EPX71017.1 - 3.5e-17 61.9 1.2 9.7e-17 60.5 0.0 2.5 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC Myb_DNA-bind_6 PF13921.1 EPX71017.1 - 0.0089 16.1 0.1 0.036 14.1 0.1 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Asp PF00026.18 EPX71018.1 - 3.6e-47 161.1 4.3 4.3e-47 160.9 3.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPX71018.1 - 6.2e-11 42.5 1.4 8.6e-10 38.8 0.3 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EPX71018.1 - 8.8e-06 25.4 0.1 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EPX71018.1 - 1.3e-05 25.6 0.6 0.027 14.9 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease RVP PF00077.15 EPX71018.1 - 0.00021 21.1 0.0 0.29 11.0 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease TAXi_C PF14541.1 EPX71018.1 - 0.081 12.4 0.1 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DUF4538 PF15061.1 EPX71019.1 - 0.1 11.8 0.0 0.25 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Spc24 PF08286.6 EPX71020.1 - 1e-27 96.1 4.4 1e-27 96.1 3.0 1.9 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Syntaphilin PF15290.1 EPX71020.1 - 0.019 14.4 2.7 0.019 14.4 1.9 2.0 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp APG6 PF04111.7 EPX71020.1 - 0.019 13.9 10.5 0.026 13.5 7.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 CCDC32 PF14989.1 EPX71020.1 - 0.04 13.7 6.5 0.85 9.4 1.6 2.2 1 1 1 2 2 2 0 Coiled-coil domain containing 32 Spc7 PF08317.6 EPX71020.1 - 0.045 12.4 16.2 0.14 10.8 11.3 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 EPX71020.1 - 0.047 11.5 8.9 0.052 11.3 6.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 EPX71020.1 - 0.058 13.2 2.1 0.083 12.7 1.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AKNA PF12443.3 EPX71020.1 - 0.18 11.8 10.5 0.69 9.9 4.9 2.3 1 1 1 2 2 2 0 AT-hook-containing transcription factor Sec2p PF06428.6 EPX71020.1 - 0.27 11.1 14.5 0.3 10.9 7.2 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.5 EPX71020.1 - 0.36 10.9 10.5 0.64 10.1 7.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4613 PF15390.1 EPX71020.1 - 0.38 8.8 4.4 0.42 8.7 3.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) HrpB7 PF09486.5 EPX71020.1 - 0.4 10.6 9.6 0.65 9.9 4.5 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Bap31 PF05529.7 EPX71020.1 - 1 8.8 9.9 1.4 8.3 6.9 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3573 PF12097.3 EPX71020.1 - 2.7 6.5 5.4 4.4 5.8 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) YlqD PF11068.3 EPX71020.1 - 3.4 7.7 13.7 5.3 7.0 9.0 1.7 1 1 0 1 1 1 0 YlqD protein Laminin_II PF06009.7 EPX71020.1 - 3.4 7.4 10.5 5.4 6.7 6.8 1.5 1 1 0 1 1 1 0 Laminin Domain II Spore_III_AB PF09548.5 EPX71020.1 - 4.8 6.9 9.6 4.9 6.8 5.6 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) RRN7 PF11781.3 EPX71021.1 - 1.9e-07 30.4 2.3 3.3e-07 29.6 1.6 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 eIF-5a PF01287.15 EPX71022.1 - 3.5e-27 94.1 0.7 5e-27 93.6 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EPX71022.1 - 8.4e-05 22.1 1.0 8.4e-05 22.1 0.7 1.8 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 EPX71022.1 - 0.0084 15.9 0.1 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.7 EPX71023.1 - 2.3e-130 435.5 9.8 2.8e-130 435.2 6.8 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family TelA PF05816.6 EPX71023.1 - 0.045 12.4 0.2 0.13 10.8 0.1 1.7 1 1 0 1 1 1 0 Toxic anion resistance protein (TelA) Ank_4 PF13637.1 EPX71024.1 - 1.2e-10 41.6 4.5 0.0061 17.0 0.1 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPX71024.1 - 2.5e-10 40.5 0.6 2e-05 24.8 0.5 3.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPX71024.1 - 7.2e-07 29.2 3.4 2e-05 24.6 0.0 3.7 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPX71024.1 - 4.4e-06 26.4 4.7 0.011 15.8 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 EPX71024.1 - 2.4e-05 23.9 3.8 0.0046 16.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat CENP-Q PF13094.1 EPX71024.1 - 0.15 12.0 8.1 0.36 10.8 5.1 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.14 EPX71024.1 - 1.3 6.7 8.4 1.9 6.2 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S24 PF00717.18 EPX71026.1 - 3.8e-07 29.6 0.1 8.8e-07 28.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EPX71026.1 - 4.4e-05 23.0 0.0 0.01 15.3 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Pkinase PF00069.20 EPX71027.1 - 2.5e-08 33.3 0.0 4.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71027.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase INCENP_ARK-bind PF03941.10 EPX71028.1 - 1.2e-22 79.4 4.9 2.1e-22 78.6 2.1 2.4 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Exo5 PF09810.4 EPX71029.1 - 5.3e-82 275.6 0.3 7e-82 275.2 0.2 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Cas_Cas4 PF01930.12 EPX71029.1 - 0.12 12.2 2.9 7.3 6.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF83 ARD PF03079.9 EPX71031.1 - 3.7e-48 163.4 0.1 4.3e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EPX71031.1 - 2e-09 36.8 0.0 3.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EPX71031.1 - 3.8e-06 26.6 0.0 5.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EPX71031.1 - 0.055 12.8 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_8 PF13621.1 EPX71031.1 - 0.095 12.1 0.0 0.12 11.9 0.0 1.3 1 1 0 1 1 1 0 Cupin-like domain Cupin_6 PF12852.2 EPX71031.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Cupin RF-1 PF00472.15 EPX71032.1 - 4.5e-23 81.2 6.6 7.3e-23 80.5 4.6 1.3 1 0 0 1 1 1 1 RF-1 domain DUF2992 PF11208.3 EPX71032.1 - 0.024 14.5 6.1 0.037 13.9 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Peptidase_S49_N PF08496.5 EPX71032.1 - 0.97 9.2 4.1 1.7 8.4 2.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Histone PF00125.19 EPX71033.1 - 2.6e-31 107.5 0.3 3.5e-31 107.1 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPX71033.1 - 0.0022 17.9 0.8 0.0062 16.5 0.6 1.8 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EPX71033.1 - 0.0033 17.5 0.2 0.0051 16.9 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EPX71033.1 - 0.054 12.7 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Antimicrobial12 PF08107.6 EPX71033.1 - 0.069 12.7 0.1 3.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Pleurocidin family SPC12 PF06645.8 EPX71034.1 - 4e-18 64.9 1.6 5.3e-18 64.5 1.1 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ECF-ribofla_trS PF07155.7 EPX71034.1 - 0.063 13.0 1.2 0.072 12.8 0.3 1.5 2 0 0 2 2 2 0 ECF-type riboflavin transporter, S component SdpI PF13630.1 EPX71034.1 - 0.6 9.8 3.4 0.9 9.2 2.3 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family Rpr2 PF04032.11 EPX71035.1 - 3.8e-21 74.7 8.9 4.6e-21 74.4 6.2 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.11 EPX71035.1 - 0.14 12.1 5.0 0.17 11.8 3.5 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain A2L_zn_ribbon PF08792.5 EPX71035.1 - 0.4 10.1 5.3 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain SIR2 PF02146.12 EPX71035.1 - 1.4 8.5 4.9 2.2 8.0 3.4 1.3 1 1 0 1 1 1 0 Sir2 family Zn_Tnp_IS1595 PF12760.2 EPX71035.1 - 4.2 7.2 10.2 1.6 8.5 4.8 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain MaoC_dehydratas PF01575.14 EPX71036.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain zf-C2H2 PF00096.21 EPX71037.1 - 1.3e-08 34.7 5.6 0.00048 20.3 1.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPX71037.1 - 3.6e-05 23.7 6.9 0.049 13.9 1.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EPX71037.1 - 0.097 12.8 1.6 0.17 12.0 1.1 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EPX71037.1 - 1.1 9.7 4.8 2 8.8 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Histone PF00125.19 EPX71038.1 - 7.2e-15 54.8 0.4 8.7e-15 54.6 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPX71038.1 - 7.1e-06 25.9 0.1 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EPX71038.1 - 5.8e-05 23.1 0.1 8.2e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EPX71038.1 - 8.5e-05 22.4 0.1 0.00012 21.9 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 EPX71038.1 - 0.012 14.8 0.0 0.013 14.8 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EPX71038.1 - 0.029 14.0 0.0 0.037 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated DUF1819 PF08849.6 EPX71038.1 - 0.1 12.0 0.6 0.36 10.2 0.1 1.8 1 1 1 2 2 2 0 Putative inner membrane protein (DUF1819) TFIID_20kDa PF03847.8 EPX71038.1 - 0.1 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 EPX71039.1 - 6.8e-32 109.4 0.1 1.1e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EPX71039.1 - 6.3e-06 26.2 0.0 9.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPX71039.1 - 0.0024 17.8 0.2 0.0056 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPX71039.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Rav1p_C PF12234.3 EPX71040.1 - 2.5e-150 501.6 6.7 4.4e-150 500.8 4.6 1.4 1 1 0 1 1 1 1 RAVE protein 1 C terminal PH PF00169.24 EPX71040.1 - 0.76 10.0 4.2 0.83 9.8 0.6 3.0 2 2 0 2 2 2 0 PH domain UQ_con PF00179.21 EPX71041.1 - 5.5e-52 174.9 0.0 6.3e-52 174.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPX71041.1 - 0.075 12.9 0.1 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 RWD domain EMP70 PF02990.11 EPX71042.1 - 2.8e-190 633.2 14.4 3.8e-190 632.8 10.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Med4 PF10018.4 EPX71043.1 - 4.4e-24 84.9 4.0 5.9e-24 84.4 2.7 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 MRP-S26 PF14943.1 EPX71043.1 - 0.028 13.9 1.7 0.054 13.0 1.2 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF342 PF03961.8 EPX71043.1 - 0.031 12.6 1.6 0.045 12.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin_2 PF14523.1 EPX71043.1 - 0.093 12.7 8.4 0.029 14.3 3.6 1.8 2 1 0 2 2 2 0 Syntaxin-like protein His_kinase PF06580.8 EPX71043.1 - 0.21 11.4 3.2 0.13 12.2 0.8 1.7 2 0 0 2 2 2 0 Histidine kinase DUF3810 PF12725.2 EPX71043.1 - 0.27 10.0 4.5 0.11 11.4 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Reo_sigmaC PF04582.7 EPX71043.1 - 0.42 9.7 3.7 0.66 9.1 2.6 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 EPX71043.1 - 6.2 6.8 8.3 2.1 8.3 0.3 2.7 3 0 0 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 EPX71043.1 - 6.7 7.1 8.3 2.8 8.3 3.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF972) PCI PF01399.22 EPX71044.1 - 1.1e-13 51.4 0.0 1.1e-12 48.1 0.0 2.4 2 0 0 2 2 2 1 PCI domain Apc3 PF12895.2 EPX71044.1 - 0.018 15.1 0.2 0.056 13.5 0.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Cellulase PF00150.13 EPX71045.1 - 1.6e-17 63.6 7.7 2.4e-17 63.0 5.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_L16 PF00252.13 EPX71047.1 - 2.2e-34 118.0 0.3 2.7e-34 117.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e HMGL-like PF00682.14 EPX71048.1 - 3.2e-75 252.8 0.1 5.1e-75 252.1 0.1 1.3 1 0 0 1 1 1 1 HMGL-like DUF2624 PF11116.3 EPX71048.1 - 0.0036 17.7 0.1 1.3 9.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2624) Apc4 PF12896.2 EPX71048.1 - 0.051 12.8 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Mito_fiss_reg PF05308.6 EPX71048.1 - 0.067 12.5 0.5 2.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator NUC173 PF08161.7 EPX71049.1 - 1.8e-06 27.4 3.2 0.029 13.7 0.0 3.3 2 1 1 3 3 3 2 NUC173 domain HEAT PF02985.17 EPX71049.1 - 0.0022 17.9 1.0 5 7.4 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat DUF1546 PF07571.8 EPX71049.1 - 0.025 14.7 0.1 0.082 13.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) PSP1 PF04468.7 EPX71050.1 - 9.4e-34 115.2 1.0 1.6e-33 114.5 0.7 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region zf-CCCH PF00642.19 EPX71053.1 - 2.3e-22 78.1 16.5 2.1e-12 46.3 2.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPX71053.1 - 1.6 8.8 16.9 0.092 12.7 3.0 2.9 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Dynamin_N PF00350.18 EPX71054.1 - 3.3e-42 144.1 0.0 1.1e-41 142.4 0.0 2.0 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EPX71054.1 - 4.6e-10 38.7 1.0 2.6e-07 29.7 0.1 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EPX71054.1 - 0.00035 20.4 0.0 0.0015 18.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPX71054.1 - 0.0022 18.4 0.5 0.0055 17.2 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein TRAPP PF04051.11 EPX71055.1 - 1e-45 155.0 0.1 1.2e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Acyltransferase PF01553.16 EPX71056.1 - 6.9e-13 48.1 0.0 6.7e-12 44.9 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase RNA_polI_A14 PF08203.6 EPX71057.1 - 4e-15 55.8 0.1 4e-15 55.8 0.1 2.3 1 1 1 2 2 2 1 Yeast RNA polymerase I subunit RPA14 CAF-1_p150 PF11600.3 EPX71057.1 - 0.0014 18.1 19.1 0.0015 17.9 13.2 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2126 PF09899.4 EPX71057.1 - 0.13 10.2 2.8 0.16 9.9 2.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) RR_TM4-6 PF06459.7 EPX71057.1 - 0.34 10.7 13.0 0.38 10.6 9.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BTV_NS2 PF04514.7 EPX71057.1 - 1.1 8.1 9.9 1.1 8.0 6.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1510 PF07423.6 EPX71057.1 - 1.5 8.1 16.4 1.6 8.0 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 EPX71057.1 - 1.7 8.5 8.6 1.8 8.4 5.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Ycf1 PF05758.7 EPX71057.1 - 2.3 5.8 10.6 2.1 5.9 7.3 1.1 1 0 0 1 1 1 0 Ycf1 NARP1 PF12569.3 EPX71057.1 - 3 6.4 20.2 4.1 6.0 14.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 U79_P34 PF03064.11 EPX71057.1 - 3.9 6.9 13.1 6 6.3 9.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Herpes_DNAp_acc PF04929.7 EPX71057.1 - 4.2 6.2 10.2 4.4 6.1 7.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Leucyl-specific PF14795.1 EPX71057.1 - 5.5 6.9 6.2 12 5.7 4.3 1.6 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain PBP_sp32 PF07222.7 EPX71057.1 - 6.9 5.7 10.4 9 5.3 7.2 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PHD PF00628.24 EPX71058.1 - 0.00035 20.2 12.8 0.00061 19.4 8.9 1.4 1 0 0 1 1 1 1 PHD-finger HORMA PF02301.13 EPX71058.1 - 0.0045 16.5 1.1 0.0092 15.4 0.8 1.5 1 0 0 1 1 1 1 HORMA domain PHD_2 PF13831.1 EPX71058.1 - 0.18 11.1 7.1 0.36 10.1 4.9 1.5 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.27 EPX71059.1 - 8.9e-48 158.5 14.6 2.1e-11 43.2 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EPX71059.1 - 1.4e-10 40.7 1.2 3.4e-10 39.4 0.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPX71059.1 - 5e-09 35.5 2.1 1.6e-08 33.9 1.4 1.9 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EPX71059.1 - 3.2e-08 32.1 7.9 0.068 11.2 0.1 4.9 2 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EPX71059.1 - 0.0025 17.3 0.4 4.8 6.5 0.1 3.7 3 1 0 3 3 3 1 PQQ-like domain PQQ_3 PF13570.1 EPX71059.1 - 0.081 13.2 2.3 42 4.6 0.0 4.3 3 1 1 4 4 4 0 PQQ-like domain PRANC PF09372.5 EPX71059.1 - 0.74 9.8 0.0 0.74 9.8 0.0 3.6 3 1 1 4 4 4 0 PRANC domain SUN PF03856.8 EPX71060.1 - 2.8e-96 321.5 21.3 3.3e-96 321.3 14.8 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) PMI_typeI PF01238.16 EPX71061.1 - 2.1e-116 389.0 0.0 2.5e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EPX71061.1 - 0.00033 20.1 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EPX71061.1 - 0.11 12.2 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain NARP1 PF12569.3 EPX71062.1 - 3.1e-67 227.4 0.7 3.1e-67 227.4 0.5 2.0 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EPX71062.1 - 3.8e-14 52.0 24.6 1.8e-06 27.4 2.2 5.9 4 1 3 7 7 7 5 TPR repeat TPR_16 PF13432.1 EPX71062.1 - 3.7e-11 43.3 3.2 0.037 14.7 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPX71062.1 - 1.6e-10 40.6 3.3 0.47 11.2 0.1 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPX71062.1 - 6.3e-09 35.0 19.0 0.0062 16.3 0.0 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPX71062.1 - 4.2e-08 32.4 5.3 0.06 13.1 0.5 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPX71062.1 - 2.2e-07 30.7 12.6 0.17 11.8 0.5 5.8 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPX71062.1 - 1.1e-06 28.0 10.0 0.00082 18.9 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPX71062.1 - 4.4e-06 26.9 8.7 1.6 9.1 0.0 5.6 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EPX71062.1 - 5.3e-06 26.1 2.1 0.15 11.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EPX71062.1 - 9.1e-06 25.7 28.0 0.054 13.6 0.0 5.5 3 2 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EPX71062.1 - 1.2e-05 24.7 18.5 0.0072 15.8 0.1 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPX71062.1 - 0.00055 19.9 10.7 0.13 12.4 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPX71062.1 - 0.0011 19.3 5.7 0.48 11.0 0.6 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EPX71062.1 - 0.0037 17.1 0.5 1.8 8.5 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EPX71062.1 - 8.3 6.3 14.3 50 3.8 0.6 6.2 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 EPX71063.1 - 4.7e-09 35.4 4.0 0.0057 16.4 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPX71063.1 - 3.1e-08 33.1 8.1 0.022 14.4 0.0 3.9 3 1 0 4 4 4 3 TPR repeat TPR_8 PF13181.1 EPX71063.1 - 5.5e-08 32.0 3.4 0.0016 18.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPX71063.1 - 3.9e-07 30.5 1.7 0.13 13.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPX71063.1 - 1.1e-06 28.8 9.0 0.085 13.2 0.6 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPX71063.1 - 5.7e-06 26.5 2.1 0.33 11.7 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPX71063.1 - 9e-06 25.0 3.3 0.17 11.5 0.1 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPX71063.1 - 7.2e-05 22.6 9.6 0.017 15.0 0.7 4.8 3 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPX71063.1 - 0.00014 21.7 2.8 0.85 9.9 0.1 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPX71063.1 - 0.00038 20.0 3.5 1.2 9.1 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPX71063.1 - 0.015 15.2 2.2 5 7.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPX71063.1 - 0.016 15.6 4.8 2.9 8.5 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 EPX71063.1 - 0.018 15.0 7.7 1.1 9.2 2.2 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat HEAT_EZ PF13513.1 EPX71063.1 - 0.096 13.2 0.1 0.39 11.2 0.1 2.1 1 1 0 1 1 1 0 HEAT-like repeat TPR_20 PF14561.1 EPX71063.1 - 0.23 11.5 10.3 4.7 7.3 0.5 4.0 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EPX71063.1 - 0.31 10.9 2.5 1.1 9.1 0.2 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat UPF0020 PF01170.13 EPX71064.1 - 4.3e-10 39.4 0.0 8.3e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EPX71064.1 - 5.2e-09 36.1 0.0 9.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EPX71064.1 - 0.0093 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Peptidase_M22 PF00814.20 EPX71065.1 - 9.9e-87 290.8 0.0 1.2e-86 290.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Dna2 PF08696.6 EPX71066.1 - 3.2e-51 173.6 0.1 4.6e-36 124.0 0.0 2.5 1 1 1 2 2 2 2 DNA replication factor Dna2 AAA_12 PF13087.1 EPX71066.1 - 2.5e-49 167.3 0.0 5.3e-49 166.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPX71066.1 - 6.3e-39 133.9 0.0 3.5e-19 69.3 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EPX71066.1 - 1.2e-10 40.9 0.0 2.6e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPX71066.1 - 1.3e-07 31.4 0.0 3.7e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EPX71066.1 - 6.8e-07 29.0 0.5 0.51 9.8 0.0 4.6 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EPX71066.1 - 5.9e-05 22.5 0.4 0.00016 21.1 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EPX71066.1 - 0.00012 21.8 0.0 0.00031 20.4 0.0 1.7 1 0 0 1 1 1 1 Helicase SRP54 PF00448.17 EPX71066.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EPX71066.1 - 0.0082 16.1 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EPX71066.1 - 0.014 14.4 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EPX71066.1 - 0.045 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ArgK PF03308.11 EPX71066.1 - 0.079 11.7 0.0 0.18 10.5 0.0 1.5 2 0 0 2 2 2 0 ArgK protein DUF853 PF05872.7 EPX71066.1 - 0.083 11.2 0.1 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FtsK_SpoIIIE PF01580.13 EPX71066.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Alpha-amylase PF00128.19 EPX71067.1 - 5.3e-25 88.4 0.1 1.2e-18 67.5 0.0 2.9 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EPX71067.1 - 2.3e-15 56.7 0.1 4.3e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EPX71067.1 - 8.7e-08 31.7 0.0 1.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 EPX71067.1 - 0.014 16.0 0.0 0.044 14.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain Zip PF02535.17 EPX71068.1 - 1.4e-54 185.2 5.1 1.7e-54 184.9 3.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter SIR2 PF02146.12 EPX71069.1 - 1.5e-62 210.4 0.0 2.4e-62 209.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EPX71069.1 - 6.4e-07 29.0 0.3 1.2e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EPX71069.1 - 0.0093 15.7 0.1 0.35 10.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain AAA_2 PF07724.9 EPX71070.1 - 2.9e-50 170.5 0.0 7.7e-49 165.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EPX71070.1 - 9.6e-28 97.0 0.0 3.3e-15 56.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EPX71070.1 - 6.4e-23 80.4 0.2 2e-22 78.8 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 EPX71070.1 - 9.5e-17 60.6 0.1 1.6e-08 34.3 0.0 3.3 2 0 0 2 2 2 2 Clp amino terminal domain AAA_5 PF07728.9 EPX71070.1 - 1.4e-15 57.2 0.1 4.8e-10 39.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPX71070.1 - 4.9e-14 52.7 10.2 2.9e-05 24.1 0.0 5.2 4 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 EPX71070.1 - 5.4e-13 49.2 1.2 0.00013 22.1 0.0 4.4 3 2 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 EPX71070.1 - 4.7e-10 39.2 0.0 6.7e-07 28.9 0.0 2.7 2 1 1 3 3 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EPX71070.1 - 4.7e-08 32.6 0.0 0.0048 16.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EPX71070.1 - 7.7e-07 29.4 0.0 0.01 16.1 0.0 3.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EPX71070.1 - 9.7e-07 28.1 0.0 0.016 14.4 0.0 3.3 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EPX71070.1 - 1.2e-06 29.3 7.5 0.055 14.2 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EPX71070.1 - 3.3e-05 23.3 1.0 0.16 11.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EPX71070.1 - 6.1e-05 22.7 0.7 0.37 10.5 0.0 3.9 5 0 0 5 5 3 2 Part of AAA domain Zeta_toxin PF06414.7 EPX71070.1 - 6.5e-05 22.1 0.6 0.039 13.0 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_3 PF07726.6 EPX71070.1 - 8.5e-05 22.1 0.1 0.037 13.6 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EPX71070.1 - 0.00015 21.8 0.1 0.98 9.3 0.0 3.7 3 1 0 3 3 3 2 AAA domain ABC_tran PF00005.22 EPX71070.1 - 0.00016 22.0 0.9 0.12 12.7 0.0 3.7 3 1 0 3 3 3 1 ABC transporter RNA_helicase PF00910.17 EPX71070.1 - 0.00017 21.7 0.0 1 9.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase T2SE PF00437.15 EPX71070.1 - 0.001 18.0 0.2 0.0095 14.8 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_21 PF13304.1 EPX71070.1 - 0.0011 19.0 0.0 0.4 10.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 EPX71070.1 - 0.0015 18.1 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EPX71070.1 - 0.0016 18.2 6.4 0.25 10.9 0.2 4.2 4 1 0 4 4 3 1 Archaeal ATPase DUF258 PF03193.11 EPX71070.1 - 0.0049 16.0 0.0 2.9 7.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EPX71070.1 - 0.0087 15.7 0.0 3.2 7.4 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EPX71070.1 - 0.0093 15.8 6.7 0.2 11.5 0.3 3.8 3 1 0 3 3 2 1 AAA domain NACHT PF05729.7 EPX71070.1 - 0.015 15.0 0.3 0.95 9.1 0.0 2.9 3 0 0 3 3 3 0 NACHT domain AAA_29 PF13555.1 EPX71070.1 - 0.019 14.4 0.1 8.5 5.9 0.0 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain PhoH PF02562.11 EPX71070.1 - 0.024 13.8 0.0 1.1 8.4 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein Torsin PF06309.6 EPX71070.1 - 0.026 14.4 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Torsin DUF2075 PF09848.4 EPX71070.1 - 0.029 13.3 0.0 1.8 7.4 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 EPX71070.1 - 0.05 13.6 0.0 4.4 7.3 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_10 PF12846.2 EPX71070.1 - 0.081 12.3 6.6 3.3 7.0 0.2 4.6 3 2 1 4 4 4 0 AAA-like domain UPF0079 PF02367.12 EPX71070.1 - 0.091 12.3 0.0 26 4.4 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 Occludin_ELL PF07303.8 EPX71070.1 - 0.82 10.4 4.5 2.8 8.7 3.1 1.9 1 0 0 1 1 1 0 Occludin homology domain AAA_23 PF13476.1 EPX71070.1 - 1.3 9.2 0.0 1.3 9.2 0.0 3.9 3 1 0 3 3 2 0 AAA domain IncA PF04156.9 EPX71070.1 - 1.5 8.3 9.2 4.5 6.8 6.3 1.8 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EPX71070.1 - 2.6 7.0 5.3 4.4 6.2 3.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 PCNA_N PF00705.13 EPX71071.1 - 8.7e-59 196.5 3.8 1.9e-58 195.5 2.4 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EPX71071.1 - 7.3e-53 177.8 0.0 1.3e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EPX71071.1 - 2.4e-07 30.1 0.0 2.8e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EPX71071.1 - 0.00039 19.4 0.2 0.0033 16.4 0.1 2.1 1 1 1 2 2 2 1 Hus1-like protein dCMP_cyt_deam_1 PF00383.17 EPX71072.1 - 2.4e-25 88.1 0.4 3.9e-25 87.4 0.3 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region PRK PF00485.13 EPX71072.1 - 0.006 16.1 0.0 0.013 15.0 0.0 1.7 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family Bd3614-deam PF14439.1 EPX71072.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase AAA_17 PF13207.1 EPX71072.1 - 0.026 15.3 0.0 0.061 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain Ribosomal_S13 PF00416.17 EPX71073.1 - 3e-40 136.9 3.0 3.6e-40 136.7 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EPX71073.1 - 0.00098 17.7 0.0 0.0012 17.4 0.0 1.2 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EPX71073.1 - 0.0054 16.7 0.4 0.025 14.6 0.1 2.1 2 1 0 2 2 2 1 Helix-hairpin-helix motif SRF-TF PF00319.13 EPX71074.1 - 0.1 11.8 0.3 0.21 10.8 0.2 1.5 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Rpp20 PF12328.3 EPX71075.1 - 4.8e-11 42.4 0.3 2.2e-07 30.6 0.0 2.0 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EPX71075.1 - 0.02 14.4 0.1 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Alba M16C_assoc PF08367.6 EPX71075.1 - 0.084 11.7 0.1 0.78 8.5 0.0 1.9 2 0 0 2 2 2 0 Peptidase M16C associated TMF_DNA_bd PF12329.3 EPX71076.1 - 0.013 15.3 2.9 0.013 15.3 2.0 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.1 EPX71076.1 - 0.3 10.5 22.5 0.018 14.4 3.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TBPIP_N PF15517.1 EPX71076.1 - 0.33 10.6 2.5 0.57 9.8 0.5 2.3 2 1 1 3 3 3 0 TBP-interacting protein N-terminus LMBR1 PF04791.11 EPX71076.1 - 0.38 9.2 6.2 0.52 8.8 4.1 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 EPX71076.1 - 1.5 8.3 20.1 4.1 6.9 13.9 1.9 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 EPX71076.1 - 1.7 7.6 19.1 0.49 9.3 11.2 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4200 PF13863.1 EPX71076.1 - 3.7 7.5 21.0 0.63 10.0 1.7 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) FlgN PF05130.7 EPX71076.1 - 7.9 6.7 20.2 0.44 10.7 6.6 2.5 1 1 1 2 2 2 0 FlgN protein Ribosomal_L4 PF00573.17 EPX71077.1 - 8.4e-45 152.5 1.4 1.1e-44 152.0 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EPX71077.1 - 1.1e-27 95.7 2.7 1.1e-27 95.7 1.9 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PIF1 PF05970.9 EPX71077.1 - 0.045 12.6 0.1 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Pro_CA PF00484.14 EPX71079.1 - 5.2e-47 159.6 0.2 5.2e-47 159.6 0.1 1.5 2 0 0 2 2 2 1 Carbonic anhydrase Ribosomal_60s PF00428.14 EPX71080.1 - 4.5e-28 97.4 13.4 5.2e-28 97.2 9.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein TT_ORF2 PF02957.10 EPX71080.1 - 0.033 14.8 0.2 0.047 14.3 0.2 1.2 1 0 0 1 1 1 0 TT viral ORF2 DUF1995 PF09353.5 EPX71080.1 - 0.12 11.9 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) SET PF00856.23 EPX71081.1 - 3.9e-13 50.0 0.2 1e-09 38.8 0.1 2.5 2 0 0 2 2 2 2 SET domain zf-MYND PF01753.13 EPX71081.1 - 1.4e-11 44.0 13.8 1.4e-11 44.0 9.6 2.2 2 0 0 2 2 2 1 MYND finger LCM PF04072.9 EPX71082.1 - 4.1e-26 91.6 0.0 6.6e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Xpo1 PF08389.7 EPX71083.1 - 1.7e-34 118.8 2.0 1.7e-34 118.8 1.4 3.6 4 0 0 4 4 4 1 Exportin 1-like protein Gon7 PF08738.5 EPX71083.1 - 0.0089 16.0 0.2 0.021 14.8 0.1 1.6 1 0 0 1 1 1 1 Gon7 family RIX1 PF08167.7 EPX71083.1 - 5.5 6.6 8.0 1.5 8.4 0.4 3.7 5 1 1 6 6 6 0 rRNA processing/ribosome biogenesis U3_snoRNA_assoc PF08297.6 EPX71084.1 - 3.8e-09 36.6 5.1 3.8e-09 36.6 3.5 2.8 1 1 1 2 2 2 1 U3 snoRNA associated CDC27 PF09507.5 EPX71084.1 - 0.49 9.5 25.4 0.82 8.8 17.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GEMIN8 PF15348.1 EPX71084.1 - 2.1 8.3 15.4 3.5 7.6 10.6 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Asp-B-Hydro_N PF05279.6 EPX71084.1 - 3.6 7.3 19.7 4.3 7.1 13.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4661 PF15576.1 EPX71084.1 - 6.9 6.2 10.7 9 5.8 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) NTF2 PF02136.15 EPX71085.1 - 1.3e-28 99.7 0.0 3e-28 98.5 0.0 1.7 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EPX71085.1 - 1.2e-10 40.8 0.1 2.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71085.1 - 6.1e-10 38.9 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPX71085.1 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif DUF605 PF04652.11 EPX71085.1 - 0.11 11.8 20.7 0.18 11.1 14.3 1.3 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EPX71085.1 - 0.41 10.5 12.4 0.5 10.2 8.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EPX71085.1 - 2.6 6.1 17.5 3.3 5.8 12.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CENP-H PF05837.7 EPX71086.1 - 1.3e-11 44.6 6.7 1.3e-11 44.6 4.6 1.6 2 0 0 2 2 2 1 Centromere protein H (CENP-H) RcbX PF02341.10 EPX71086.1 - 0.042 13.9 0.1 0.081 13.0 0.1 1.5 1 0 0 1 1 1 0 RbcX protein DUF342 PF03961.8 EPX71086.1 - 0.048 12.0 1.8 0.062 11.7 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Uds1 PF15456.1 EPX71086.1 - 0.053 13.5 5.3 0.047 13.6 1.3 2.3 2 1 0 2 2 2 0 Up-regulated During Septation TGT PF01702.13 EPX71086.1 - 0.073 12.3 0.1 0.15 11.2 0.0 1.5 1 1 0 1 1 1 0 Queuine tRNA-ribosyltransferase TMF_DNA_bd PF12329.3 EPX71086.1 - 0.16 11.7 4.2 0.42 10.4 2.9 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Vac7 PF12751.2 EPX71087.1 - 1.7e-07 30.4 14.1 4.4e-07 29.0 9.1 2.1 1 1 0 1 1 1 1 Vacuolar segregation subunit 7 Casein_kappa PF00997.13 EPX71087.1 - 1.3 8.7 6.3 0.24 11.0 1.2 1.8 2 0 0 2 2 2 0 Kappa casein DNA_pol_E_B PF04042.11 EPX71088.1 - 2.5e-49 167.3 0.8 3.7e-49 166.8 0.6 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DWNN PF08783.6 EPX71089.1 - 2.9e-33 113.6 0.2 5e-33 112.8 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EPX71089.1 - 8.2e-05 22.0 6.9 0.00026 20.4 4.8 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EPX71089.1 - 0.00016 21.5 12.4 0.00016 21.5 8.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX71089.1 - 0.003 17.1 11.0 0.003 17.1 7.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPX71089.1 - 0.0068 16.2 12.4 0.0068 16.2 8.6 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 EPX71089.1 - 0.026 14.3 2.9 0.046 13.4 2.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Thioredoxin_4 PF13462.1 EPX71089.1 - 0.04 13.9 0.9 0.14 12.1 0.0 2.3 3 0 0 3 3 3 0 Thioredoxin zf-C3HC4 PF00097.20 EPX71089.1 - 0.045 13.3 14.5 0.096 12.3 10.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 EPX71089.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.0 2 0 0 2 2 1 0 Zinc knuckle zf-CCHC PF00098.18 EPX71089.1 - 0.68 9.9 5.7 0.12 12.3 0.6 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-RING_5 PF14634.1 EPX71089.1 - 1.7 8.4 19.3 0.12 12.1 9.6 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 EPX71089.1 - 7.8 6.1 11.5 17 5.1 8.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DEAD PF00270.24 EPX71090.1 - 1.1e-44 151.9 0.0 2e-43 147.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX71090.1 - 1.1e-27 95.7 0.0 2.4e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX71090.1 - 2.3e-05 24.3 0.0 0.00028 20.7 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EPX71090.1 - 0.043 12.2 0.0 0.52 8.6 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 EPX71090.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain POTRA_2 PF08479.6 EPX71090.1 - 0.12 12.1 0.0 0.49 10.0 0.0 2.0 3 0 0 3 3 3 0 POTRA domain, ShlB-type Phos_pyr_kin PF08543.7 EPX71091.1 - 1.5e-73 246.9 0.4 2.2e-73 246.5 0.2 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EPX71091.1 - 2.8e-23 82.7 0.0 4.3e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EPX71091.1 - 0.00014 21.1 0.3 0.00053 19.2 0.2 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EPX71092.1 - 8.9e-80 267.4 0.6 1.3e-79 266.9 0.4 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EPX71092.1 - 1.6e-50 171.8 0.6 2.6e-50 171.1 0.4 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.10 EPX71092.1 - 4e-05 22.9 3.1 0.00033 19.9 0.0 2.5 2 1 0 2 2 2 1 Hydroxyethylthiazole kinase family PfkB PF00294.19 EPX71092.1 - 0.037 13.1 0.0 0.067 12.3 0.0 1.4 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Carb_kinase PF01256.12 EPX71092.1 - 0.06 12.6 0.4 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate kinase SPT16 PF08644.6 EPX71093.1 - 1.1e-58 197.3 0.1 3.9e-58 195.6 0.1 2.0 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EPX71093.1 - 1.1e-51 174.5 0.2 1.1e-51 174.5 0.1 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EPX71093.1 - 2.1e-26 92.7 0.0 3.9e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EPX71093.1 - 2.3e-23 81.9 0.0 6.1e-23 80.6 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.1 EPX71093.1 - 0.23 11.0 0.0 0.49 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Nol1_Nop2_Fmu PF01189.12 EPX71094.1 - 2.1e-98 329.1 0.0 3.5e-98 328.4 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Met_10 PF02475.11 EPX71094.1 - 0.00038 20.1 0.0 0.00071 19.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EPX71094.1 - 0.32 11.6 0.0 0.32 11.6 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain ABC_membrane PF00664.18 EPX71095.1 - 4.1e-92 308.4 37.4 1.9e-48 165.2 9.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPX71095.1 - 2.6e-67 225.3 0.0 4.4e-33 114.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EPX71095.1 - 1.3e-12 48.3 0.0 0.096 12.6 0.0 4.6 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EPX71095.1 - 2.9e-12 46.3 4.9 4.5e-05 22.7 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EPX71095.1 - 3.2e-09 35.8 2.8 0.0001 21.0 0.0 3.5 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EPX71095.1 - 6.1e-08 32.0 1.5 0.00079 18.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPX71095.1 - 6.3e-07 28.7 0.0 0.019 14.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EPX71095.1 - 7e-07 30.0 0.0 0.03 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPX71095.1 - 5.1e-06 26.5 0.2 0.11 12.5 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EPX71095.1 - 3.2e-05 23.4 0.7 0.23 10.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 EPX71095.1 - 0.00029 20.4 0.3 1.6 8.2 0.0 3.6 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.1 EPX71095.1 - 0.0006 19.6 1.6 1.6 8.7 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EPX71095.1 - 0.00064 20.1 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPX71095.1 - 0.0053 16.6 0.8 3.6 7.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPX71095.1 - 0.0072 16.6 0.3 7.6 6.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EPX71095.1 - 0.0073 16.4 6.0 3.4 7.8 0.5 4.3 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPX71095.1 - 0.011 15.5 0.3 5 6.8 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) MobB PF03205.9 EPX71095.1 - 0.017 14.8 0.2 8.8 6.0 0.1 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EPX71095.1 - 0.019 14.6 0.0 2.1 8.1 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 EPX71095.1 - 0.043 13.7 0.4 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EPX71095.1 - 0.053 12.9 0.3 23 4.3 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EPX71095.1 - 0.055 13.3 0.0 27 4.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.18 EPX71095.1 - 0.087 12.7 0.5 12 5.8 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EPX71095.1 - 0.087 12.2 1.3 14 4.9 0.0 3.1 4 0 0 4 4 3 0 AAA-like domain Zeta_toxin PF06414.7 EPX71095.1 - 0.089 11.8 1.1 3.6 6.6 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin NB-ARC PF00931.17 EPX71095.1 - 0.12 11.2 0.2 9 5.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ER_lumen_recept PF00810.13 EPX71096.1 - 2.2e-50 170.9 10.4 3.2e-50 170.4 7.2 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EPX71096.1 - 0.16 11.5 14.7 0.056 12.9 1.2 3.6 3 1 1 4 4 4 0 PQ loop repeat DUF788 PF05620.6 EPX71096.1 - 4.4 7.1 8.7 0.34 10.7 1.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF788) UCH PF00443.24 EPX71097.1 - 2.3e-51 174.4 0.0 4e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPX71097.1 - 2.5e-16 59.9 0.0 4.3e-15 55.9 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4 PF00097.20 EPX71098.1 - 6.3e-07 28.9 2.9 1.5e-05 24.5 2.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPX71098.1 - 9e-07 28.8 5.9 3.2e-06 27.0 4.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPX71098.1 - 2e-06 27.5 6.7 4.1e-06 26.5 4.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPX71098.1 - 0.00034 20.2 7.1 0.00077 19.0 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPX71098.1 - 0.00036 20.3 1.4 0.00036 20.3 1.0 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPX71098.1 - 0.0055 16.3 1.0 0.0055 16.3 0.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EPX71098.1 - 0.05 13.3 10.7 0.17 11.6 7.4 2.0 1 1 0 1 1 1 0 zinc-RING finger domain Lar_restr_allev PF14354.1 EPX71098.1 - 0.066 13.5 3.7 0.076 13.3 1.1 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar PAM2 PF07145.10 EPX71098.1 - 0.38 10.3 3.0 1.1 8.8 2.1 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zf-rbx1 PF12678.2 EPX71098.1 - 0.62 10.2 4.1 2.3 8.4 2.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger FYVE PF01363.16 EPX71098.1 - 0.77 9.6 6.4 2.1 8.3 4.4 1.7 1 0 0 1 1 1 0 FYVE zinc finger Atg8 PF02991.11 EPX71099.1 - 3.3e-50 168.3 0.2 3.8e-50 168.1 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EPX71099.1 - 2e-06 27.8 0.0 2.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Pro_isomerase PF00160.16 EPX71100.1 - 8.1e-46 156.0 0.1 9.8e-46 155.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Stc1 PF12898.2 EPX71102.1 - 1.6e-15 56.8 11.0 2.1e-15 56.5 7.6 1.1 1 0 0 1 1 1 1 Stc1 domain ATE_N PF04376.8 EPX71102.1 - 6.5 6.6 9.6 1.2 8.9 1.0 2.3 1 1 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus HECT PF00632.20 EPX71103.1 - 2.3e-83 279.9 0.1 4.3e-83 279.0 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Chorismate_bind PF00425.13 EPX71104.1 - 3.5e-74 249.3 0.0 5.5e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EPX71104.1 - 8.1e-32 110.2 0.0 1.1e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EPX71104.1 - 1.8e-16 60.4 0.0 3.7e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EPX71104.1 - 1.5e-08 34.3 0.0 2.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 zf-C4H2 PF10146.4 EPX71105.1 - 0.0061 16.6 15.9 0.0061 16.6 11.0 2.6 1 1 0 2 2 2 1 Zinc finger-containing protein DUF3373 PF11853.3 EPX71105.1 - 0.77 8.2 5.0 8.6 4.7 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) EzrA PF06160.7 EPX71105.1 - 0.94 7.5 30.6 0.77 7.8 4.3 2.8 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF3450 PF11932.3 EPX71105.1 - 4.3 6.5 18.4 0.62 9.2 3.6 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3450) Fungal_trans PF04082.13 EPX71106.1 - 7.4e-11 41.4 4.2 7.4e-11 41.4 2.9 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX71106.1 - 7.8e-09 35.3 5.7 2.5e-08 33.6 4.0 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EutH PF04346.7 EPX71106.1 - 0.06 12.2 0.3 0.093 11.6 0.2 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH Acid_PPase PF12689.2 EPX71107.1 - 5.9e-61 204.9 0.0 6.6e-61 204.8 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EPX71107.1 - 0.00076 19.7 0.9 0.0045 17.2 0.0 2.0 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 EPX71107.1 - 0.0011 18.7 0.1 0.0015 18.2 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.21 EPX71107.1 - 0.041 14.2 0.3 0.22 11.8 0.0 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 EPX71108.1 - 1.1e-17 63.1 15.9 0.00058 19.6 0.0 8.8 10 0 0 10 10 10 6 WD domain, G-beta repeat PSII_BNR PF14870.1 EPX71108.1 - 0.0041 16.1 0.0 0.046 12.7 0.0 2.5 3 0 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 Syja_N PF02383.13 EPX71109.1 - 1.1e-86 290.5 1.5 1.3e-86 290.2 1.0 1.1 1 0 0 1 1 1 1 SacI homology domain YfhO PF09586.5 EPX71109.1 - 0.0059 14.6 1.1 0.0085 14.1 0.8 1.2 1 0 0 1 1 1 1 Bacterial membrane protein YfhO AA_kinase PF00696.23 EPX71110.1 - 4.1e-41 141.1 0.0 6.6e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EPX71110.1 - 1.2e-12 47.0 0.6 2.6e-09 36.3 0.0 3.0 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 EPX71110.1 - 1.3e-11 43.8 1.3 2.1e-10 39.9 0.1 2.7 2 0 0 2 2 2 1 ACT domain NAPRTase PF04095.11 EPX71110.1 - 0.03 13.6 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Pescadillo_N PF06732.6 EPX71111.1 - 7.7e-130 432.1 2.1 7.7e-130 432.1 1.5 2.5 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 EPX71111.1 - 3.4e-10 39.9 0.0 1.6e-09 37.7 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Cytokin_check_N PF10407.4 EPX71112.1 - 1.5e-16 59.7 0.3 3e-16 58.8 0.2 1.4 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus MCM PF00493.18 EPX71113.1 - 1.4e-133 444.8 0.0 1.9e-133 444.3 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPX71113.1 - 1.8e-30 105.9 0.3 6.3e-29 100.9 0.1 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPX71113.1 - 1.7e-07 30.5 0.0 1.2e-05 24.5 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPX71113.1 - 9.7e-07 28.5 0.0 2.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPX71113.1 - 0.013 15.1 0.0 0.049 13.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPX71113.1 - 0.041 13.3 0.0 0.55 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EPX71113.1 - 0.079 12.6 0.2 1.7 8.3 0.1 2.5 2 0 0 2 2 2 0 NTPase Ribonuc_red_sm PF00268.16 EPX71114.1 - 4.1e-118 393.4 0.5 4.9e-118 393.2 0.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain TRM PF02005.11 EPX71115.1 - 1e-147 492.0 0.0 1.3e-147 491.6 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EPX71115.1 - 1e-05 25.2 0.2 1.8e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EPX71115.1 - 0.0049 16.8 0.1 0.014 15.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF917 PF06032.7 EPX71115.1 - 0.062 11.8 0.0 0.096 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) DEAD PF00270.24 EPX71116.1 - 1.4e-06 27.9 0.0 3.3e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EPX71116.1 - 0.068 12.9 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RRM_1 PF00076.17 EPX71117.1 - 6.6e-17 60.9 0.0 9.9e-17 60.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71117.1 - 1.1e-12 47.7 0.0 1.4e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX71117.1 - 0.0001 22.0 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.20 EPX71118.1 - 6.5e-11 41.4 0.0 6.5e-11 41.4 0.0 1.7 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.1 EPX71118.1 - 6.3e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 S4 domain NTP_transferase PF00483.18 EPX71119.1 - 6.2e-27 94.4 0.0 8.3e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EPX71119.1 - 1.7e-10 39.9 4.4 1.8e-05 24.0 0.2 4.4 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EPX71119.1 - 3e-08 33.9 0.0 9.7e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain Fucokinase PF07959.7 EPX71119.1 - 0.003 16.1 1.3 0.032 12.8 0.3 2.1 2 0 0 2 2 2 1 L-fucokinase Oxidored_nitro PF00148.14 EPX71119.1 - 0.023 13.3 0.1 0.52 8.8 0.0 2.5 2 1 1 3 3 3 0 Nitrogenase component 1 type Oxidoreductase IspD PF01128.14 EPX71119.1 - 0.12 11.8 0.1 0.62 9.5 0.0 2.2 3 0 0 3 3 3 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pex14_N PF04695.8 EPX71120.1 - 6.9e-24 84.4 3.1 1.2e-17 64.1 0.2 3.7 2 2 1 3 3 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1759 PF03564.10 EPX71120.1 - 0.0025 17.6 1.0 0.0025 17.6 0.7 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1759) DUF3584 PF12128.3 EPX71120.1 - 0.019 12.3 13.2 0.022 12.0 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SRP54_N PF02881.14 EPX71120.1 - 0.05 13.6 2.8 0.058 13.4 0.5 2.2 2 0 0 2 2 1 0 SRP54-type protein, helical bundle domain CHDCT2 PF08074.6 EPX71120.1 - 0.055 13.1 2.3 0.068 12.9 0.7 1.8 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain AAA_13 PF13166.1 EPX71120.1 - 0.066 11.6 13.2 0.1 11.0 9.1 1.2 1 0 0 1 1 1 0 AAA domain ISG65-75 PF11727.3 EPX71120.1 - 0.082 11.9 6.1 0.12 11.3 4.2 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein FUSC PF04632.7 EPX71120.1 - 0.091 11.1 4.5 0.11 10.9 3.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CLAMP PF14769.1 EPX71120.1 - 0.099 12.7 4.9 0.77 9.9 0.4 2.7 3 0 0 3 3 2 0 Flagellar C1a complex subunit C1a-32 Imm6 PF14434.1 EPX71120.1 - 0.1 12.3 3.9 1.7 8.3 2.7 2.4 1 1 0 1 1 1 0 Immunity protein Imm6 Peptidase_C6 PF00851.13 EPX71120.1 - 0.14 10.7 3.4 0.19 10.3 2.4 1.1 1 0 0 1 1 1 0 Helper component proteinase RmuC PF02646.11 EPX71120.1 - 0.16 10.8 9.2 1.3 7.7 0.2 2.2 1 1 1 2 2 2 0 RmuC family TMF_DNA_bd PF12329.3 EPX71120.1 - 0.17 11.6 17.0 1.6 8.5 3.9 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PilJ PF13675.1 EPX71120.1 - 0.24 11.7 8.2 2.9 8.2 5.6 2.4 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Vps53_N PF04100.7 EPX71120.1 - 0.29 9.8 9.3 0.65 8.7 6.3 1.6 1 1 1 2 2 2 0 Vps53-like, N-terminal GvpK PF05121.7 EPX71120.1 - 0.33 10.8 6.3 0.95 9.3 1.2 2.9 3 0 0 3 3 3 0 Gas vesicle protein K DUF1664 PF07889.7 EPX71120.1 - 0.46 10.2 8.2 0.22 11.3 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.11 EPX71120.1 - 0.49 8.9 4.7 0.57 8.7 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.14 EPX71120.1 - 0.5 8.1 6.9 0.75 7.5 4.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L29 PF00831.18 EPX71120.1 - 0.55 9.9 12.4 0.62 9.7 1.3 3.0 3 0 0 3 3 3 0 Ribosomal L29 protein DASH_Dad3 PF08656.5 EPX71120.1 - 0.89 9.2 8.4 6.5 6.5 0.2 3.1 3 1 1 4 4 4 0 DASH complex subunit Dad3 Enkurin PF13864.1 EPX71120.1 - 1.2 9.4 12.1 0.87 9.8 1.5 2.7 1 1 1 2 2 2 0 Calmodulin-binding Prefoldin_2 PF01920.15 EPX71120.1 - 1.3 8.8 13.9 2.7 7.7 0.6 3.0 1 1 2 3 3 3 0 Prefoldin subunit Prefoldin PF02996.12 EPX71120.1 - 1.5 8.4 12.2 10 5.7 0.9 3.2 2 1 0 2 2 2 0 Prefoldin subunit Laminin_II PF06009.7 EPX71120.1 - 1.8 8.3 10.0 1.9 8.2 5.9 1.7 1 1 0 1 1 1 0 Laminin Domain II Snapin_Pallidin PF14712.1 EPX71120.1 - 2.4 8.5 13.8 4.8 7.5 0.9 2.9 1 1 1 3 3 3 0 Snapin/Pallidin DUF4164 PF13747.1 EPX71120.1 - 2.4 8.3 15.8 5.4 7.2 0.8 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) BLOC1_2 PF10046.4 EPX71120.1 - 2.5 8.2 10.8 3.2 7.9 0.6 2.4 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 EPX71120.1 - 3 6.7 17.7 4.8 6.1 12.0 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Fzo_mitofusin PF04799.8 EPX71120.1 - 3.3 7.0 9.8 7 6.0 0.6 2.4 1 1 1 2 2 2 0 fzo-like conserved region TPR_MLP1_2 PF07926.7 EPX71120.1 - 3.7 7.3 18.0 1.4e+02 2.2 11.5 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ACCA PF03255.9 EPX71120.1 - 5.2 6.6 7.2 2.6 7.5 1.1 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit IL6 PF00489.12 EPX71120.1 - 5.5 6.5 8.5 2.1 7.9 0.3 2.6 1 1 0 2 2 2 0 Interleukin-6/G-CSF/MGF family IncA PF04156.9 EPX71120.1 - 6.2 6.3 16.6 15 5.1 11.5 1.6 1 1 0 1 1 1 0 IncA protein HR1 PF02185.11 EPX71120.1 - 6.4 6.5 10.6 0.49 10.1 1.1 2.4 2 0 0 2 2 2 0 Hr1 repeat Syntaxin-6_N PF09177.6 EPX71120.1 - 7.2 7.0 14.8 0.81 10.1 4.0 2.8 2 1 1 3 3 2 0 Syntaxin 6, N-terminal DUF2203 PF09969.4 EPX71120.1 - 9.8 6.4 6.6 1.2e+02 2.8 4.5 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) 2OG-FeII_Oxy_2 PF13532.1 EPX71121.1 - 5.3e-41 140.5 0.0 1.7e-40 138.9 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EPX71121.1 - 0.036 14.3 0.0 0.066 13.5 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF747 PF05346.6 EPX71122.1 - 1.4e-111 372.7 15.0 1.4e-111 372.7 10.4 1.5 2 0 0 2 2 2 1 Eukaryotic membrane protein family Complex1_LYR_1 PF13232.1 EPX71123.1 - 2.2e-13 50.1 0.3 3.2e-13 49.6 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EPX71123.1 - 1.7e-12 46.9 0.3 2.8e-12 46.2 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ribosomal_S22 PF08136.6 EPX71123.1 - 0.38 10.9 4.9 1.2 9.3 1.7 2.6 2 1 0 2 2 2 0 30S ribosomal protein subunit S22 family SPRY PF00622.23 EPX71124.1 - 1.5e-14 54.1 0.3 6.8e-13 48.7 0.0 2.7 2 1 1 3 3 3 1 SPRY domain PHD PF00628.24 EPX71124.1 - 0.0017 17.9 8.0 0.0032 17.1 5.6 1.5 1 0 0 1 1 1 1 PHD-finger zf-DHHC PF01529.15 EPX71125.1 - 3e-34 117.9 12.3 3e-34 117.9 8.5 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase Bystin PF05291.6 EPX71126.1 - 4.5e-134 446.1 0.2 7.1e-134 445.4 0.2 1.2 1 0 0 1 1 1 1 Bystin Astro_capsid PF03115.9 EPX71126.1 - 5.9 5.0 8.7 9.1 4.3 6.0 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Sec63 PF02889.11 EPX71127.1 - 6.6e-145 482.1 2.5 1.1e-90 304.0 0.4 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EPX71127.1 - 3.1e-56 189.4 4.5 6.4e-30 103.8 0.7 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EPX71127.1 - 5.8e-18 65.3 0.5 1e-09 38.5 0.2 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPX71127.1 - 2.5e-15 56.0 0.0 3.4e-06 26.8 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPX71127.1 - 5.3e-07 29.8 1.9 0.031 14.4 0.0 4.1 3 2 0 3 3 3 2 AAA domain SNF2_N PF00176.18 EPX71127.1 - 3.8e-05 22.6 0.4 0.01 14.6 0.1 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain PhoH PF02562.11 EPX71127.1 - 0.00012 21.4 0.0 0.019 14.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EPX71127.1 - 0.001 18.7 0.0 1.5 8.6 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_10 PF12846.2 EPX71127.1 - 0.0024 17.3 1.0 7.3 5.9 0.0 4.7 3 2 2 5 5 5 1 AAA-like domain IstB_IS21 PF01695.12 EPX71127.1 - 0.0057 16.0 0.5 5.6 6.3 0.0 3.4 4 0 0 4 4 4 2 IstB-like ATP binding protein Longin PF13774.1 EPX71128.1 - 6.6e-18 64.0 0.0 1.1e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EPX71128.1 - 3.5e-14 52.1 0.7 4.9e-14 51.6 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Imm43 PF15602.1 EPX71128.1 - 0.075 12.9 0.2 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 43 Snf7 PF03357.16 EPX71129.1 - 2e-21 76.1 12.4 2.5e-21 75.7 8.6 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EPX71129.1 - 0.033 13.6 2.4 0.05 12.9 1.6 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Tfb2 PF03849.9 EPX71130.1 - 1e-145 485.0 0.0 1.4e-145 484.6 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EPX71130.1 - 0.00046 19.9 0.0 0.00082 19.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT PF03061.17 EPX71131.1 - 1.3e-12 47.6 0.0 1.7e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily ChaC PF04752.7 EPX71132.1 - 1.7e-59 200.7 0.0 1.9e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein Med17 PF10156.4 EPX71133.1 - 1.1e-67 228.3 4.1 1.4e-67 228.0 2.8 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Arf PF00025.16 EPX71135.1 - 1.6e-66 222.8 0.0 1.8e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EPX71135.1 - 7.5e-11 41.3 0.1 1.1e-07 30.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EPX71135.1 - 7.7e-09 35.0 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPX71135.1 - 1.7e-06 27.9 0.0 5.5e-06 26.3 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 EPX71135.1 - 1.6e-05 24.3 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX71135.1 - 2.3e-05 24.8 0.0 3.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EPX71135.1 - 0.00043 19.5 0.0 0.00045 19.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EPX71135.1 - 0.024 14.1 0.0 0.1 12.0 0.0 2.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF1840 PF08895.6 EPX71135.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) GTP_EFTU PF00009.22 EPX71135.1 - 0.11 11.9 0.0 7.4 5.9 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain VHS PF00790.14 EPX71136.1 - 1.5e-27 95.9 0.0 4.6e-27 94.3 0.0 1.9 3 0 0 3 3 3 1 VHS domain GAT PF03127.9 EPX71136.1 - 6.4e-08 32.4 0.8 1.3e-07 31.5 0.6 1.5 1 0 0 1 1 1 1 GAT domain Med10 PF09748.4 EPX71138.1 - 4.1e-30 104.2 1.2 4.7e-30 104.0 0.8 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Hormone_recep PF00104.25 EPX71138.1 - 0.00032 19.8 0.3 0.023 13.8 0.0 2.3 2 1 1 3 3 3 2 Ligand-binding domain of nuclear hormone receptor TAFH PF07531.9 EPX71138.1 - 0.13 11.9 0.1 2.6 7.7 0.0 2.2 1 1 1 2 2 2 0 NHR1 homology to TAF zf-MYND PF01753.13 EPX71139.1 - 1.3e-06 28.1 20.4 2.8e-06 27.0 14.1 1.6 1 1 0 1 1 1 1 MYND finger HAT PF02184.11 EPX71140.1 - 4.5e-25 87.0 69.1 2.9e-17 62.0 4.8 12.6 14 1 0 14 14 13 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EPX71140.1 - 1.2e-23 81.4 12.9 0.0072 16.8 0.0 11.3 6 4 7 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 EPX71140.1 - 4.2e-19 68.6 0.1 2.5e-06 27.7 0.0 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPX71140.1 - 7.7e-16 58.3 16.6 0.00024 21.6 0.0 7.8 6 2 4 10 10 9 5 Tetratricopeptide repeat Suf PF05843.9 EPX71140.1 - 8.9e-16 58.4 27.2 0.001 18.8 1.2 7.9 4 3 3 7 7 7 4 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EPX71140.1 - 3.5e-13 48.3 11.3 0.0035 17.1 0.0 9.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPX71140.1 - 3.4e-10 39.6 9.4 1.9 9.0 0.0 8.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EPX71140.1 - 4.6e-10 38.9 6.9 0.02 14.5 0.0 6.7 5 1 1 6 6 6 3 TPR repeat TPR_12 PF13424.1 EPX71140.1 - 4.7e-09 36.0 12.8 0.43 10.5 0.0 7.5 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 EPX71140.1 - 5.9e-09 35.0 7.4 0.55 10.1 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPX71140.1 - 1.1e-07 31.0 2.3 3.8 7.5 0.0 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPX71140.1 - 1.3e-06 28.1 4.3 0.15 12.2 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPX71140.1 - 1.2e-05 24.5 12.8 0.44 9.5 0.4 5.2 2 2 2 4 4 4 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EPX71140.1 - 0.0013 18.5 2.8 9.9 6.1 0.1 4.4 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 EPX71140.1 - 0.0018 17.7 4.3 0.8 9.4 0.0 6.2 8 0 0 8 8 8 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EPX71140.1 - 0.0019 17.1 25.5 0.014 14.3 1.7 5.8 2 2 2 6 6 6 2 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.7 EPX71140.1 - 0.0064 16.2 21.2 0.039 13.7 1.9 5.9 4 3 1 5 5 5 1 Mad3/BUB1 homology region 1 PUA PF01472.15 EPX71141.1 - 2.4e-18 65.6 0.2 3.6e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 PUA domain Hira PF07569.6 EPX71142.1 - 1.7e-60 203.9 0.0 3.2e-60 203.0 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EPX71142.1 - 4.8e-44 146.7 30.4 4.1e-11 42.3 0.2 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 EPX71142.1 - 4.5e-09 35.6 2.0 4.5e-09 35.6 1.4 2.2 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.7 EPX71142.1 - 1.2e-05 24.8 1.5 0.49 10.1 0.1 4.7 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EPX71142.1 - 0.0053 16.4 0.1 0.31 10.7 0.0 3.6 4 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF3793 PF12672.2 EPX71142.1 - 0.1 12.1 0.0 10 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) TPR_2 PF07719.12 EPX71143.1 - 6.3e-07 28.8 8.6 0.0061 16.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPX71143.1 - 1.9e-06 27.4 5.2 0.21 11.2 0.0 4.9 4 0 0 4 4 4 3 TPR repeat TPR_8 PF13181.1 EPX71143.1 - 4.5e-06 26.0 7.6 0.0028 17.3 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPX71143.1 - 0.00096 19.4 4.9 0.41 11.2 0.0 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPX71143.1 - 0.0025 17.3 10.1 0.012 15.2 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPX71143.1 - 0.0036 17.1 1.4 0.93 9.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPX71143.1 - 0.0073 16.0 0.5 0.41 10.5 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPX71143.1 - 0.05 14.2 1.0 5 8.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPX71143.1 - 0.1 13.3 2.2 1.1 10.0 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ATP-synt_Eps PF04627.8 EPX71144.1 - 1e-17 63.3 0.4 1.3e-17 63.0 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain ChAPs PF09295.5 EPX71145.1 - 1.2e-152 508.3 0.0 1.7e-152 507.7 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EPX71145.1 - 4e-06 26.3 1.4 0.0071 15.9 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EPX71145.1 - 2.2e-05 24.0 0.9 2.4 8.3 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPX71145.1 - 0.00029 20.4 0.0 3 7.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EPX71145.1 - 0.0019 18.2 1.8 0.33 11.1 0.4 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EPX71145.1 - 0.0026 18.2 2.9 5.7 7.8 0.0 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPX71145.1 - 0.0032 17.7 1.3 6.6 7.1 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPX71145.1 - 0.04 13.8 2.8 0.27 11.1 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPX71145.1 - 0.075 13.7 2.8 0.22 12.2 0.1 2.9 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF1162 PF06650.7 EPX71146.1 - 1.7e-60 204.5 9.0 4.1e-60 203.3 1.4 3.8 3 1 0 3 3 3 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EPX71146.1 - 3e-36 123.5 0.2 1.2e-35 121.6 0.1 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EPX71146.1 - 0.0023 18.0 0.0 0.0062 16.6 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Sds3 PF08598.6 EPX71147.1 - 2.9e-13 49.8 11.1 2.9e-13 49.8 7.7 4.0 2 2 0 2 2 2 1 Sds3-like ABC1 PF03109.11 EPX71148.1 - 1.8e-25 89.1 0.0 1.2e-23 83.2 0.0 2.7 1 1 0 1 1 1 1 ABC1 family Ribosomal_L34 PF00468.12 EPX71149.1 - 1.1e-19 69.7 8.8 1.7e-19 69.2 6.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 CactinC_cactus PF09732.4 EPX71150.1 - 3e-06 26.8 0.4 5e-06 26.1 0.3 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein zf-met PF12874.2 EPX71150.1 - 9.4e-06 25.6 1.2 1.9e-05 24.6 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EPX71150.1 - 0.021 14.1 0.3 0.036 13.3 0.2 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Methyltransf_12 PF08242.7 EPX71152.1 - 4e-14 52.8 0.0 1.4e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX71152.1 - 4.7e-13 49.1 0.0 9.9e-13 48.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX71152.1 - 3.3e-11 43.5 0.0 1.1e-10 41.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX71152.1 - 8.1e-10 38.9 0.0 2.9e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX71152.1 - 2.6e-07 31.1 0.0 8.3e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX71152.1 - 3.8e-07 29.8 0.0 1.4e-06 28.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EPX71152.1 - 5.5e-06 25.5 0.0 0.043 12.7 0.0 2.2 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.13 EPX71152.1 - 2.1e-05 23.7 0.0 3.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EPX71152.1 - 8.1e-05 22.6 0.0 0.0002 21.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EPX71152.1 - 0.0008 20.2 0.0 0.0018 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EPX71152.1 - 0.0017 18.0 0.1 0.15 11.6 0.0 2.9 2 1 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.9 EPX71152.1 - 0.0079 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 EPX71152.1 - 0.081 12.3 0.0 2.1 7.7 0.0 2.7 2 1 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Aminotran_3 PF00202.16 EPX71153.1 - 1.3e-103 346.3 0.0 1.6e-103 346.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.12 EPX71153.1 - 0.13 11.3 0.1 2.8 6.8 0.0 2.5 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family FAA_hydrolase PF01557.13 EPX71154.1 - 1.5e-50 171.6 0.0 1.8e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RibD_C PF01872.12 EPX71155.1 - 5.8e-25 88.0 0.0 7.2e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain TUG-UBL1 PF11470.3 EPX71156.1 - 1.1e-16 60.5 0.3 3.1e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EPX71156.1 - 0.00023 21.1 0.0 0.001 19.0 0.0 2.1 1 1 1 2 2 2 1 UBX domain DUF953 PF06110.6 EPX71157.1 - 2.2e-13 49.6 0.0 2.6e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) DUF3521 PF12035.3 EPX71157.1 - 0.03 14.1 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) Thioredoxin_8 PF13905.1 EPX71157.1 - 0.038 14.1 0.0 0.15 12.1 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.1 EPX71157.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Ribosomal_S19e PF01090.14 EPX71158.1 - 6.3e-60 200.6 0.1 7e-60 200.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e DUF948 PF06103.6 EPX71159.1 - 0.04 13.7 3.1 4.1 7.3 0.1 4.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Aldedh PF00171.17 EPX71160.1 - 2e-127 425.3 0.0 2.3e-127 425.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Spt4 PF06093.8 EPX71161.1 - 2e-22 78.8 0.0 2.5e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DUF4448 PF14610.1 EPX71162.1 - 9.6e-16 57.8 0.2 1.2e-15 57.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EPX71162.1 - 0.016 15.6 0.5 0.032 14.6 0.3 1.7 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pkinase PF00069.20 EPX71163.1 - 1e-37 129.7 0.0 7e-19 67.9 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71163.1 - 5.8e-13 48.5 0.0 1.7e-09 37.1 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EPX71163.1 - 0.0003 20.6 0.4 0.0028 17.4 0.0 2.4 3 1 1 4 4 4 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EPX71163.1 - 0.0021 17.1 0.0 0.0057 15.6 0.0 1.6 2 0 0 2 2 2 1 Fructosamine kinase DUF1087 PF06465.8 EPX71163.1 - 0.12 12.2 0.9 0.3 11.0 0.6 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1087) SBDS PF01172.13 EPX71164.1 - 3.3e-17 62.0 0.2 3.6e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RRM_1 PF00076.17 EPX71166.1 - 2e-46 155.5 0.0 2.6e-17 62.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71166.1 - 5.9e-27 93.4 0.0 3.1e-09 36.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX71166.1 - 1.4e-24 85.7 0.0 8.3e-13 47.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPX71166.1 - 4.7e-06 26.3 0.0 4e-05 23.4 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif SNF2_N PF00176.18 EPX71167.1 - 1.2e-69 234.4 0.1 1.8e-69 233.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPX71167.1 - 1.1e-12 47.5 0.0 2.3e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EPX71167.1 - 1.4e-06 27.8 2.6 6.5e-06 25.7 2.0 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPX71167.1 - 4.8e-06 26.5 6.0 4.8e-06 26.5 4.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX71167.1 - 2.1e-05 24.1 4.6 5.2e-05 22.8 3.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPX71167.1 - 2.9e-05 23.8 5.4 9.4e-05 22.1 3.8 1.9 1 1 0 1 1 1 1 Ring finger domain DEAD PF00270.24 EPX71167.1 - 0.00015 21.2 0.0 0.00039 19.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.1 EPX71167.1 - 0.0005 19.7 3.0 0.00093 18.8 0.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EPX71167.1 - 0.0018 17.9 5.2 0.0061 16.2 3.6 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPX71167.1 - 0.0021 17.9 4.9 0.0061 16.4 3.2 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EPX71167.1 - 0.012 15.3 1.9 0.037 13.8 1.3 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.6 EPX71167.1 - 0.11 12.2 1.0 0.25 11.0 0.7 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) CN_hydrolase PF00795.17 EPX71168.1 - 1.3e-13 50.7 0.0 1.8e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BP28CT PF08146.7 EPX71169.1 - 9.2e-38 129.3 5.2 9.2e-38 129.3 3.6 3.9 4 0 0 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EPX71169.1 - 2e-12 47.1 0.1 2e-12 47.1 0.1 5.7 7 0 0 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EPX71169.1 - 1.1e-06 28.8 3.3 0.24 11.6 0.1 5.6 4 1 0 4 4 4 2 HEAT repeats Peptidase_M24 PF00557.19 EPX71170.1 - 1.4e-12 47.6 0.0 2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 F-112 PF09645.5 EPX71170.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 F-112 protein DHBP_synthase PF00926.14 EPX71171.1 - 1.8e-80 268.7 0.0 2e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase RFC1 PF08519.7 EPX71172.1 - 1.5e-56 190.4 0.2 3.9e-56 189.1 0.0 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EPX71172.1 - 3e-13 49.7 0.0 6.8e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EPX71172.1 - 6.9e-13 48.9 0.0 1.6e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPX71172.1 - 5.1e-06 26.6 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EPX71172.1 - 5.4e-05 22.0 0.0 0.00046 18.9 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EPX71172.1 - 0.00033 20.3 0.0 0.00079 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 EPX71172.1 - 0.00038 20.0 0.0 0.00074 19.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 EPX71172.1 - 0.0011 19.7 0.0 0.0032 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPX71172.1 - 0.0025 17.7 0.0 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPX71172.1 - 0.0025 16.9 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus SAGA-Tad1 PF12767.2 EPX71172.1 - 0.0054 16.4 0.0 0.0054 16.4 0.0 3.0 2 1 0 2 2 1 1 Transcriptional regulator of RNA polII, SAGA, subunit NTPase_1 PF03266.10 EPX71172.1 - 0.012 15.2 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.1 EPX71172.1 - 0.013 15.5 0.2 0.06 13.3 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EPX71172.1 - 0.033 14.4 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPX71172.1 - 0.035 13.9 0.0 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPX71172.1 - 0.079 12.6 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EPX71172.1 - 0.13 11.9 0.1 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Rgp1 PF08737.5 EPX71173.1 - 1.1e-59 202.5 0.0 1.7e-59 201.9 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 EPX71173.1 - 3.2e-06 27.0 6.9 0.00013 21.8 0.0 4.0 3 1 1 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EPX71173.1 - 0.0018 18.3 0.0 0.37 10.9 0.0 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Transglut_C PF00927.17 EPX71173.1 - 0.038 14.0 0.3 0.33 11.0 0.0 2.5 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Spo0M PF07070.6 EPX71173.1 - 0.059 12.6 0.0 1.7 7.9 0.0 2.8 3 0 0 3 3 3 0 SpoOM protein TPR_1 PF00515.23 EPX71174.1 - 2.5e-46 153.4 42.9 1.8e-08 33.6 0.1 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EPX71174.1 - 1.2e-43 146.5 31.6 2.2e-11 43.2 0.7 6.6 2 2 5 8 8 8 8 TPR repeat TPR_2 PF07719.12 EPX71174.1 - 1.4e-40 133.9 39.6 5.4e-06 25.9 0.0 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 EPX71174.1 - 2.9e-28 97.6 34.2 1.9e-07 30.8 0.3 7.5 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_8 PF13181.1 EPX71174.1 - 3.3e-27 92.1 32.7 8.8e-05 22.0 0.1 10.3 8 1 2 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 EPX71174.1 - 1.2e-26 92.7 20.8 2.8e-07 31.0 0.1 7.0 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 EPX71174.1 - 4.1e-25 85.9 18.1 0.0034 17.8 0.0 9.6 2 2 8 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 EPX71174.1 - 5.7e-25 85.3 23.1 0.0056 16.7 0.0 10.6 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.1 EPX71174.1 - 2.1e-18 66.4 21.0 0.00074 19.8 0.1 7.0 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 EPX71174.1 - 3.2e-17 61.7 28.8 0.0042 17.4 0.0 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 EPX71174.1 - 2.7e-13 48.6 29.5 0.014 15.1 0.1 9.9 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 EPX71174.1 - 1.6e-10 40.6 19.3 0.007 16.1 0.1 6.7 2 2 4 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 EPX71174.1 - 2.7e-10 40.2 20.8 7.3e-07 29.2 2.9 4.3 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EPX71174.1 - 7.5e-06 25.9 0.3 1.2 9.3 0.1 4.9 2 2 2 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.5 EPX71174.1 - 0.0038 16.0 1.2 1.1 7.9 0.0 2.6 2 1 2 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) BAF1_ABF1 PF04684.8 EPX71174.1 - 0.32 9.7 46.7 0.66 8.7 32.4 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SNAP PF14938.1 EPX71174.1 - 5.7 6.0 19.2 11 5.0 0.2 4.7 3 3 1 4 4 4 0 Soluble NSF attachment protein, SNAP IF-2B PF01008.12 EPX71175.1 - 8.6e-72 241.4 0.4 1e-71 241.2 0.3 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PEP-utilizers PF00391.18 EPX71175.1 - 0.032 13.7 0.5 0.37 10.3 0.1 2.9 3 1 0 3 3 3 0 PEP-utilising enzyme, mobile domain Ribosomal_S10 PF00338.17 EPX71176.1 - 1.1e-22 79.6 0.0 1.8e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Suf PF05843.9 EPX71177.1 - 1.5e-20 74.1 16.0 4.1e-05 23.4 0.7 6.2 4 2 1 5 5 5 4 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EPX71177.1 - 3.9e-15 54.9 0.2 8 7.4 0.0 10.5 10 1 1 11 11 11 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPX71177.1 - 2.2e-10 40.2 3.9 0.065 13.1 0.0 6.7 4 3 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPX71177.1 - 6.7e-09 36.1 0.3 0.19 12.4 0.0 6.7 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPX71177.1 - 1.1e-07 32.1 0.0 8.8 6.7 0.0 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EPX71177.1 - 2.3e-07 30.6 8.9 0.18 11.6 0.0 6.3 6 1 1 7 7 6 2 Mad3/BUB1 homology region 1 NRDE-2 PF08424.5 EPX71177.1 - 3.7e-07 29.3 12.0 0.00072 18.5 0.4 5.6 3 3 1 4 4 4 3 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 EPX71177.1 - 3.2e-06 26.6 0.7 6.5 6.4 0.0 6.5 6 1 0 6 6 6 1 TPR repeat TPR_15 PF13429.1 EPX71177.1 - 1.7e-05 24.0 3.7 1 8.3 0.0 5.7 4 2 1 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.4 EPX71177.1 - 0.0018 17.6 0.3 0.02 14.2 0.0 2.8 2 1 1 3 3 3 1 26S proteasome subunit RPN7 TPR_8 PF13181.1 EPX71177.1 - 0.021 14.5 11.5 0.97 9.3 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.15 EPX71177.1 - 0.046 13.7 0.8 12 6.1 0.0 4.3 4 0 0 4 4 4 0 PPR repeat TPR_2 PF07719.12 EPX71177.1 - 0.046 13.6 18.5 2.5 8.2 0.1 8.1 11 0 0 11 11 10 0 Tetratricopeptide repeat Apc3 PF12895.2 EPX71177.1 - 1.6 8.9 7.8 5.2 7.2 0.1 4.8 6 1 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 Sec7 PF01369.15 EPX71178.1 - 5.9e-64 215.2 0.8 4.6e-63 212.3 0.2 2.7 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 EPX71178.1 - 5.2e-21 74.8 1.7 4.3e-11 42.5 2.0 3.3 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal MCM PF00493.18 EPX71179.1 - 3.9e-139 463.0 0.8 6.2e-139 462.4 0.5 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPX71179.1 - 2.3e-24 86.2 0.1 1.1e-23 84.0 0.1 2.2 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPX71179.1 - 4.5e-08 32.4 0.0 7e-07 28.6 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EPX71179.1 - 0.00078 18.9 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EPX71179.1 - 0.002 17.7 0.0 0.0049 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPX71179.1 - 0.0043 16.7 0.0 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Tir_receptor_M PF03549.9 EPX71179.1 - 0.014 15.5 0.0 0.051 13.7 0.0 1.9 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain SF3b10 PF07189.6 EPX71180.1 - 3e-36 123.0 0.0 3.4e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Spc97_Spc98 PF04130.8 EPX71181.1 - 4.8e-13 48.2 13.5 2.7e-07 29.3 2.8 2.1 2 0 0 2 2 2 2 Spc97 / Spc98 family UQ_con PF00179.21 EPX71182.1 - 2.2e-35 121.1 0.1 3e-35 120.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RNase_PH PF01138.16 EPX71183.1 - 2.4e-31 108.7 0.0 3.2e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ThiF PF00899.16 EPX71184.1 - 3.6e-46 156.3 0.0 1.1e-30 106.1 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EPX71184.1 - 1.9e-41 141.1 0.0 4.3e-41 140.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EPX71184.1 - 5.2e-32 109.2 0.4 3.3e-23 81.0 0.0 2.5 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EPX71184.1 - 1.3e-26 91.6 1.0 2.5e-22 78.0 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Kinesin PF00225.18 EPX71186.1 - 1.8e-99 332.6 5.4 1.8e-99 332.6 3.8 2.1 2 0 0 2 2 2 1 Kinesin motor domain SbcD_C PF12320.3 EPX71186.1 - 0.023 14.7 4.7 0.069 13.2 3.3 1.8 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain IncA PF04156.9 EPX71186.1 - 6 6.4 18.2 15 5.0 12.5 1.8 1 1 0 1 1 1 0 IncA protein TRAPPC-Trs85 PF12739.2 EPX71187.1 - 5.2e-79 265.8 0.6 5.2e-79 265.8 0.4 1.6 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Apc3 PF12895.2 EPX71187.1 - 0.065 13.3 0.5 0.23 11.6 0.4 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Snf7 PF03357.16 EPX71188.1 - 1.1e-15 57.4 2.9 1.6e-15 56.9 2.0 1.2 1 0 0 1 1 1 1 Snf7 DUF2454 PF10521.4 EPX71189.1 - 6.3e-24 84.4 2.1 6.3e-24 84.4 1.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) G-patch PF01585.18 EPX71190.1 - 3e-09 36.5 0.0 6.4e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 G-patch domain Gpi16 PF04113.9 EPX71191.1 - 8.1e-158 525.9 3.8 3.9e-156 520.3 2.6 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Pkinase PF00069.20 EPX71192.1 - 7.6e-73 244.8 0.0 1.1e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71192.1 - 4e-48 163.7 0.0 6.8e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EPX71192.1 - 7.4e-22 77.5 0.1 7.4e-22 77.5 0.0 3.0 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 EPX71192.1 - 1.2e-08 34.2 0.1 2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 EPX71192.1 - 0.0017 17.6 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 DSHCT (NUC185) domain APH PF01636.18 EPX71192.1 - 0.031 13.9 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EPX71192.1 - 0.034 13.1 0.0 0.071 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L32p PF01783.18 EPX71193.1 - 8.9e-15 54.6 5.0 1.2e-14 54.2 3.5 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family Rad50_zn_hook PF04423.9 EPX71193.1 - 0.091 12.2 0.5 0.64 9.5 0.0 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif Auto_anti-p27 PF06677.7 EPX71193.1 - 0.29 10.9 3.6 4.5 7.1 0.1 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Spindle_Spc25 PF08234.7 EPX71194.1 - 1.1e-24 86.2 0.4 1.1e-24 86.2 0.3 2.3 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 THOC7 PF05615.8 EPX71194.1 - 0.00079 19.7 18.8 0.0013 19.0 13.0 1.3 1 0 0 1 1 1 1 Tho complex subunit 7 Spc7 PF08317.6 EPX71194.1 - 0.0013 17.5 15.0 0.0017 17.0 10.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein APG6 PF04111.7 EPX71194.1 - 0.0034 16.4 17.7 0.0034 16.4 12.3 2.0 1 1 1 2 2 2 1 Autophagy protein Apg6 DUF869 PF05911.6 EPX71194.1 - 0.0048 15.1 13.9 0.0066 14.7 9.7 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Prominin PF05478.6 EPX71194.1 - 0.096 10.2 10.9 0.23 8.9 7.6 1.5 2 0 0 2 2 2 0 Prominin Metal_resist PF13801.1 EPX71194.1 - 0.61 10.0 3.5 1 9.3 2.2 1.6 1 1 0 1 1 1 0 Heavy-metal resistance DUF1664 PF07889.7 EPX71194.1 - 1.5 8.6 8.9 3.1 7.6 5.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Img2 PF05046.9 EPX71194.1 - 2.4 8.4 6.2 1.2 9.4 2.4 1.9 1 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Cmyb_C PF09316.5 EPX71194.1 - 2.7 7.6 8.5 4.3 6.9 5.9 1.4 1 0 0 1 1 1 0 C-myb, C-terminal LMBR1 PF04791.11 EPX71194.1 - 3.6 6.0 6.2 4.4 5.7 4.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4349 PF14257.1 EPX71194.1 - 6.1 5.9 10.9 8.5 5.5 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2400 PF09674.5 EPX71194.1 - 6.2 6.4 9.1 21 4.7 4.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) TMPIT PF07851.8 EPX71194.1 - 7 5.6 11.3 12 4.9 7.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF812 PF05667.6 EPX71194.1 - 7.1 5.0 22.8 30 2.9 15.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) F1F0-ATPsyn_F PF10791.4 EPX71196.1 - 1.4e-34 118.1 0.5 1.5e-34 118.0 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EPX71196.1 - 0.056 13.4 0.1 0.064 13.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Med21 PF11221.3 EPX71197.1 - 4.8e-31 107.6 5.5 5.5e-31 107.4 3.8 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Beach PF02138.13 EPX71197.1 - 2e-06 27.4 1.3 2.3e-06 27.2 0.9 1.0 1 0 0 1 1 1 1 Beige/BEACH domain Med9 PF07544.8 EPX71197.1 - 1.5e-05 24.5 3.4 1.9e-05 24.3 1.2 1.9 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 MAD PF05557.8 EPX71197.1 - 0.0028 15.8 2.7 0.0031 15.6 1.9 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein HAP1_N PF04849.8 EPX71197.1 - 0.0072 15.3 7.8 0.0087 15.0 5.4 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF4404 PF14357.1 EPX71197.1 - 0.0094 16.3 1.4 0.0094 16.3 1.0 1.9 2 1 1 3 3 2 1 Domain of unknown function (DUF4404) ISG65-75 PF11727.3 EPX71197.1 - 0.018 14.1 2.5 0.024 13.7 1.7 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Fez1 PF06818.10 EPX71197.1 - 0.019 15.0 3.4 0.026 14.5 2.4 1.2 1 0 0 1 1 1 0 Fez1 DUF607 PF04678.8 EPX71197.1 - 0.041 13.7 0.5 0.051 13.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF342 PF03961.8 EPX71197.1 - 0.051 11.9 5.0 0.058 11.7 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 EPX71197.1 - 0.11 12.3 5.6 0.2 11.5 3.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Sipho_Gp157 PF05565.6 EPX71197.1 - 0.16 11.5 5.8 0.17 11.4 2.8 1.9 2 0 0 2 2 2 0 Siphovirus Gp157 DivIC PF04977.10 EPX71197.1 - 0.17 11.4 3.3 0.55 9.7 2.3 1.8 1 0 0 1 1 1 0 Septum formation initiator DUF948 PF06103.6 EPX71197.1 - 0.2 11.5 3.1 1.4 8.8 0.1 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TrbI_Ftype PF09677.5 EPX71197.1 - 0.2 11.4 1.2 0.47 10.3 0.3 1.8 1 1 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) AAA_23 PF13476.1 EPX71197.1 - 0.27 11.5 5.7 0.31 11.3 3.9 1.1 1 0 0 1 1 1 0 AAA domain COG2 PF06148.6 EPX71197.1 - 0.27 11.0 3.2 1.1 9.0 2.2 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 THOC7 PF05615.8 EPX71197.1 - 0.34 11.1 5.9 1.2 9.4 4.0 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 RasGAP PF00616.14 EPX71197.1 - 0.85 9.2 6.1 4.6 6.8 2.2 2.2 2 1 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase DUF4355 PF14265.1 EPX71197.1 - 1.6 8.7 8.8 2.5 8.0 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) RNase_T PF00929.19 EPX71198.1 - 3.8e-29 102.0 0.0 9.7e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EPX71198.1 - 3.2e-05 23.4 0.1 0.00017 21.1 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease BRICHOS PF04089.9 EPX71198.1 - 0.0088 15.8 0.2 0.11 12.3 0.0 2.6 2 1 0 2 2 2 1 BRICHOS domain Arm PF00514.18 EPX71199.1 - 1.9e-89 290.7 13.6 5.5e-12 45.0 0.0 8.6 9 0 0 9 9 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EPX71199.1 - 2.6e-27 94.9 0.0 6.5e-07 29.5 0.0 5.6 1 1 5 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 EPX71199.1 - 1e-20 73.5 0.3 2.5e-07 30.9 0.0 6.2 5 2 1 6 6 6 4 HEAT-like repeat IBB PF01749.15 EPX71199.1 - 7.9e-20 70.8 8.3 1.5e-19 69.9 5.7 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EPX71199.1 - 1.2e-18 65.4 0.8 0.00012 21.8 0.0 8.1 8 0 0 8 8 8 3 HEAT repeat Adaptin_N PF01602.15 EPX71199.1 - 9.9e-08 30.7 0.0 2.5e-05 22.8 0.0 3.2 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EPX71199.1 - 0.0001 22.1 0.0 4.7 7.1 0.0 4.5 2 2 3 5 5 5 3 V-ATPase subunit H Arm_2 PF04826.8 EPX71199.1 - 0.00047 19.3 0.0 0.18 10.9 0.0 3.2 1 1 2 3 3 3 2 Armadillo-like Proteasom_PSMB PF10508.4 EPX71199.1 - 0.00092 17.6 2.0 0.018 13.3 0.1 3.2 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit Mo25 PF08569.6 EPX71199.1 - 0.0065 15.5 0.7 0.015 14.3 0.0 1.9 2 0 0 2 2 2 1 Mo25-like HEAT_PBS PF03130.11 EPX71199.1 - 0.044 14.2 0.1 17 6.2 0.0 3.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Mt_ATP-synt_B PF05405.9 EPX71200.1 - 3.6e-47 159.8 7.9 4.8e-47 159.4 5.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DNA_pol_A_exo1 PF01612.15 EPX71200.1 - 0.047 13.1 0.1 0.065 12.7 0.1 1.2 1 0 0 1 1 1 0 3'-5' exonuclease DUF212 PF02681.9 EPX71200.1 - 0.19 11.4 1.8 0.2 11.3 0.1 1.7 2 0 0 2 2 2 0 Divergent PAP2 family FliT PF05400.8 EPX71200.1 - 0.3 11.5 3.5 0.16 12.3 0.5 2.0 2 0 0 2 2 2 0 Flagellar protein FliT DivIC PF04977.10 EPX71200.1 - 0.97 8.9 5.2 0.67 9.4 0.3 2.7 2 1 1 3 3 3 0 Septum formation initiator Reo_sigmaC PF04582.7 EPX71200.1 - 1.2 8.2 5.5 1.7 7.7 3.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EPX71200.1 - 1.8 8.3 8.7 5.9 6.7 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 EPX71200.1 - 8.4 6.3 7.6 2.1 8.3 0.3 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CBF PF03914.12 EPX71201.1 - 1.6e-39 134.9 0.1 3.5e-39 133.8 0.1 1.6 1 0 0 1 1 1 1 CBF/Mak21 family YcbB PF08664.5 EPX71201.1 - 0.15 11.8 1.1 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 YcbB domain PGI PF00342.14 EPX71202.1 - 1.1e-218 726.5 0.0 1.3e-218 726.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Mito_carr PF00153.22 EPX71203.1 - 2.9e-50 167.9 5.1 5.6e-17 61.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4243 PF14027.1 EPX71204.1 - 6.2e-05 22.5 0.0 8.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) PPR_2 PF13041.1 EPX71205.1 - 0.051 13.5 0.4 6.2 6.8 0.0 3.8 4 0 0 4 4 4 0 PPR repeat family Methyltransf_33 PF10017.4 EPX71206.1 - 5.3e-26 90.9 0.4 9.1e-26 90.2 0.2 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EPX71206.1 - 1.4e-24 86.8 1.4 1.8e-23 83.2 0.1 2.6 2 1 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 Methyltransf_25 PF13649.1 EPX71206.1 - 3.4e-05 24.1 0.0 7.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.2 EPX71206.1 - 6.2e-05 23.3 0.9 0.00017 21.9 0.6 1.8 1 0 0 1 1 1 1 DinB superfamily Methyltransf_32 PF13679.1 EPX71206.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SH3_1 PF00018.23 EPX71208.1 - 2.3e-13 49.2 0.1 4.4e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPX71208.1 - 7.9e-12 44.5 0.5 1.3e-11 43.9 0.1 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EPX71208.1 - 9.8e-12 44.1 0.0 1.5e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DPM3 PF08285.6 EPX71209.1 - 2.2e-24 85.0 0.3 2.5e-24 84.9 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Inos-1-P_synth PF01658.12 EPX71209.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase PALP PF00291.20 EPX71210.1 - 2.4e-74 250.3 0.3 3e-74 250.0 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EPX71210.1 - 2.2e-39 132.9 0.0 1.7e-20 72.4 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ph1570 PF09638.5 EPX71210.1 - 0.037 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Ph1570 protein Thi4 PF01946.12 EPX71211.1 - 8.2e-105 348.9 0.0 1.5e-104 348.1 0.0 1.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EPX71211.1 - 3.5e-09 36.0 0.9 8e-07 28.2 0.8 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPX71211.1 - 5.8e-06 25.4 0.3 7.4e-05 21.8 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPX71211.1 - 5.8e-06 26.2 0.4 1.9e-05 24.6 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPX71211.1 - 1.4e-05 25.0 0.1 2.3e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPX71211.1 - 2e-05 23.6 2.2 0.0017 17.3 0.7 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EPX71211.1 - 9.2e-05 21.6 0.1 0.00013 21.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPX71211.1 - 0.0004 20.5 0.3 0.00053 20.1 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPX71211.1 - 0.0013 18.5 1.4 0.0035 17.1 0.1 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EPX71211.1 - 0.0051 15.5 0.4 0.0089 14.6 0.3 1.4 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.9 EPX71211.1 - 0.023 13.1 0.6 0.038 12.4 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EPX71211.1 - 0.06 12.1 0.1 0.37 9.6 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A SNARE PF05739.14 EPX71212.1 - 0.00011 21.7 0.1 0.00011 21.7 0.1 3.5 3 1 0 3 3 3 1 SNARE domain V-SNARE_C PF12352.3 EPX71212.1 - 0.00032 20.7 1.1 0.026 14.5 0.3 2.8 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus PEMT PF04191.8 EPX71213.1 - 2.2e-56 188.4 17.7 1.4e-34 118.3 0.6 3.5 3 0 0 3 3 3 2 Phospholipid methyltransferase DUF3608 PF12257.3 EPX71214.1 - 2.3e-79 266.2 1.4 3.1e-78 262.5 1.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EPX71214.1 - 6.5e-21 73.8 0.0 1.8e-20 72.4 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Metallophos PF00149.23 EPX71215.1 - 1.9e-41 141.6 0.1 2.5e-41 141.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Thioredoxin PF00085.15 EPX71216.1 - 5.6e-18 64.5 0.1 9.7e-18 63.7 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 EPX71216.1 - 4.5e-17 61.7 0.0 2.5e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.1 EPX71216.1 - 8.2e-05 22.7 0.0 0.0016 18.6 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPX71216.1 - 0.0006 19.8 0.0 0.13 12.4 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EPX71216.1 - 0.006 16.5 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like ArsC PF03960.10 EPX71216.1 - 0.024 14.7 0.0 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 ArsC family GST_N_3 PF13417.1 EPX71216.1 - 0.092 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DIM1 PF02966.11 EPX71216.1 - 0.097 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF2847 PF11009.3 EPX71216.1 - 0.12 11.9 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Nt_Gln_amidase PF09764.4 EPX71217.1 - 4.4e-51 172.7 0.3 5.2e-51 172.5 0.2 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase Siva PF05458.7 EPX71218.1 - 0.015 14.8 17.9 0.02 14.4 12.4 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) COX17 PF05051.8 EPX71219.1 - 4.8e-22 77.7 6.0 5.7e-22 77.4 4.1 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DUF3235 PF11574.3 EPX71219.1 - 0.0016 18.6 0.0 0.0021 18.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3235) Secretogranin_V PF05281.6 EPX71219.1 - 0.12 11.7 5.0 0.13 11.6 3.5 1.1 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) FA_desaturase PF00487.19 EPX71220.1 - 0.084 12.3 1.0 0.11 11.8 0.7 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Tic20 PF09685.5 EPX71220.1 - 0.09 12.7 11.6 0.15 12.0 8.0 1.2 1 0 0 1 1 1 0 Tic20-like protein CaKB PF03185.10 EPX71220.1 - 0.097 12.0 0.0 0.23 10.7 0.0 1.6 1 1 0 1 1 1 0 Calcium-activated potassium channel, beta subunit DUF2207 PF09972.4 EPX71220.1 - 1.4 7.3 3.8 1.9 7.0 2.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) WTF PF03303.8 EPX71221.1 - 0.013 14.9 0.9 0.019 14.3 0.6 1.3 1 1 0 1 1 1 0 WTF protein Synaptobrevin PF00957.16 EPX71221.1 - 0.06 12.9 2.5 0.097 12.2 0.0 2.2 2 0 0 2 2 2 0 Synaptobrevin DUF2207 PF09972.4 EPX71221.1 - 0.071 11.6 0.1 0.072 11.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF373 PF04123.8 EPX71221.1 - 0.43 9.5 2.5 0.56 9.1 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF1673 PF07895.6 EPX71222.1 - 0.19 11.2 2.4 0.7 9.3 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) DUF3671 PF12420.3 EPX71222.1 - 4.1 7.4 6.7 5.5 7.0 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF1674 PF07896.7 EPX71223.1 - 5.3e-14 52.1 1.6 9e-14 51.4 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) Tubulin PF00091.20 EPX71224.1 - 5.7e-71 238.7 0.0 9.4e-71 238.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPX71224.1 - 5.4e-46 155.7 0.0 9.6e-46 154.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EPX71224.1 - 2.1e-05 24.5 0.0 4.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EPX71224.1 - 0.0022 17.4 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain GN3L_Grn1 PF08701.6 EPX71225.1 - 2.4e-24 85.0 13.0 2.4e-24 85.0 9.0 2.6 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EPX71225.1 - 9.4e-19 67.4 0.1 7e-13 48.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPX71225.1 - 1.8e-06 27.5 0.0 0.0017 17.7 0.0 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EPX71225.1 - 0.00018 20.8 0.0 0.00058 19.1 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EPX71225.1 - 0.00026 20.2 0.1 0.00047 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MCM PF00493.18 EPX71225.1 - 0.0021 16.9 0.3 0.08 11.7 0.2 2.3 2 0 0 2 2 2 1 MCM2/3/5 family Dynamin_N PF00350.18 EPX71225.1 - 0.0023 17.7 9.8 0.021 14.6 0.1 3.9 2 2 1 3 3 3 1 Dynamin family Miro PF08477.8 EPX71225.1 - 0.0025 18.2 0.7 0.12 12.8 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein MobB PF03205.9 EPX71225.1 - 0.024 14.3 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 EPX71225.1 - 0.03 13.4 0.0 0.1 11.6 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Torsin PF06309.6 EPX71225.1 - 0.062 13.1 0.2 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.1 EPX71225.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain SAPS PF04499.10 EPX71225.1 - 0.48 9.0 4.0 1.7 7.2 3.0 1.7 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein AAA_18 PF13238.1 EPX71225.1 - 1.6 9.0 0.0 1.6 9.0 0.0 3.5 3 1 1 4 4 3 0 AAA domain CRC_subunit PF08624.5 EPX71226.1 - 1.5e-41 141.5 0.0 2.4e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit RNB PF00773.14 EPX71227.1 - 6.5e-94 314.8 0.1 8.8e-94 314.4 0.1 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EPX71227.1 - 3.2e-09 36.9 0.0 1.2e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 PIN domain 4HBT PF03061.17 EPX71228.1 - 2.6e-08 33.8 0.0 3.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Cyto_heme_lyase PF01265.12 EPX71229.1 - 5.9e-64 216.1 23.2 3e-63 213.8 10.7 2.7 1 1 1 2 2 2 1 Cytochrome c/c1 heme lyase HMG_box PF00505.14 EPX71230.1 - 1.1e-13 51.1 0.3 2.2e-13 50.2 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 EPX71230.1 - 0.0017 17.7 0.1 0.0038 16.5 0.1 1.5 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 Fes1 PF08609.5 EPX71231.1 - 2.9e-25 88.5 2.1 8.1e-23 80.7 0.2 2.5 2 0 0 2 2 2 2 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EPX71231.1 - 0.053 13.7 0.0 0.86 9.9 0.0 2.5 1 1 1 2 2 2 0 HEAT repeats G-patch_2 PF12656.2 EPX71232.1 - 7.2e-21 73.8 0.1 7.2e-21 73.8 0.1 2.5 3 0 0 3 3 3 1 DExH-box splicing factor binding site MCM_bind PF09739.4 EPX71232.1 - 0.017 14.6 0.6 0.042 13.3 0.1 1.9 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor SRP54 PF00448.17 EPX71233.1 - 1.1e-49 168.5 0.2 1.8e-49 167.8 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EPX71233.1 - 1.6e-24 86.8 19.7 7.4e-14 51.7 6.0 2.2 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 EPX71233.1 - 1.3e-07 31.5 0.8 4.4e-07 29.9 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 EPX71233.1 - 1.2e-06 28.1 0.2 5e-06 26.0 0.0 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 EPX71233.1 - 5.1e-05 23.4 0.0 0.00016 21.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EPX71233.1 - 0.00014 21.3 0.4 0.00029 20.3 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain ArgK PF03308.11 EPX71233.1 - 0.0008 18.2 0.0 0.002 16.9 0.0 1.6 1 0 0 1 1 1 1 ArgK protein ArsA_ATPase PF02374.10 EPX71233.1 - 0.0021 17.1 4.6 2.1 7.3 0.0 3.7 3 1 0 4 4 4 2 Anion-transporting ATPase AAA_16 PF13191.1 EPX71233.1 - 0.0027 17.7 0.6 0.015 15.2 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain MobB PF03205.9 EPX71233.1 - 0.011 15.4 0.0 0.033 13.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EPX71233.1 - 0.018 14.6 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 EPX71233.1 - 0.028 13.5 0.4 0.087 11.9 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MMR_HSR1 PF01926.18 EPX71233.1 - 0.036 14.0 2.0 0.068 13.1 0.4 2.3 2 1 0 2 2 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EPX71233.1 - 0.043 13.7 2.0 0.14 12.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EPX71233.1 - 0.052 13.3 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain AAA PF00004.24 EPX71233.1 - 0.055 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EPX71233.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EPX71233.1 - 0.39 11.0 0.0 0.39 11.0 0.0 2.6 2 1 0 2 2 1 0 ABC transporter Methyltransf_23 PF13489.1 EPX71234.1 - 2.3e-17 63.1 0.0 3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX71234.1 - 4.5e-10 40.1 0.0 7.1e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX71234.1 - 3.5e-09 37.0 0.0 5.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX71234.1 - 1e-08 35.5 0.0 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX71234.1 - 3.3e-08 33.2 0.0 4.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX71234.1 - 2.1e-07 31.2 0.0 4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPX71234.1 - 7e-06 25.3 0.0 1.7e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EPX71234.1 - 3.2e-05 23.3 0.0 4.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 EPX71234.1 - 0.0031 16.8 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PCMT PF01135.14 EPX71234.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EPX71234.1 - 0.024 13.6 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Pox_MCEL PF03291.11 EPX71234.1 - 0.053 12.3 0.0 2 7.2 0.0 2.4 1 1 1 2 2 2 0 mRNA capping enzyme Methyltransf_26 PF13659.1 EPX71234.1 - 0.054 13.5 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EPX71234.1 - 0.064 11.9 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) N2227 PF07942.7 EPX71234.1 - 0.089 11.7 0.1 0.18 10.7 0.0 1.5 2 0 0 2 2 2 0 N2227-like protein DUF531 PF04407.7 EPX71234.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF531) UPF0223 PF05256.7 EPX71234.1 - 0.15 12.1 1.0 8.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0223) DCP1 PF06058.8 EPX71235.1 - 1.5e-35 121.9 0.4 1.7e-35 121.7 0.2 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family WH1 PF00568.18 EPX71235.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.8 1 1 0 1 1 1 0 WH1 domain DUF3315 PF11776.3 EPX71235.1 - 0.11 12.0 0.4 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3315) zf-CHY PF05495.7 EPX71236.1 - 1e-15 57.6 11.8 1.3e-15 57.3 8.2 1.1 1 0 0 1 1 1 1 CHY zinc finger DZR PF12773.2 EPX71236.1 - 0.014 15.1 6.3 0.049 13.4 4.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EPX71236.1 - 0.031 13.7 0.1 0.031 13.7 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EPX71236.1 - 0.043 13.4 7.2 1.2 8.7 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 EPX71236.1 - 0.06 13.1 0.5 0.06 13.1 0.4 1.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Crystallin PF00525.13 EPX71236.1 - 0.063 13.4 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal zinc_ribbon_4 PF13717.1 EPX71236.1 - 0.08 12.6 7.6 1.7 8.4 0.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EPX71236.1 - 0.13 11.4 4.3 0.62 9.3 3.0 2.1 1 1 0 1 1 1 0 zinc-ribbon domain DUF2296 PF10058.4 EPX71236.1 - 0.26 11.0 4.2 0.86 9.4 2.9 2.0 1 1 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) zf-RING_3 PF14369.1 EPX71236.1 - 0.32 11.0 8.9 0.94 9.5 2.9 2.7 1 1 1 2 2 2 0 zinc-finger Trm112p PF03966.11 EPX71236.1 - 0.36 11.2 3.1 0.97 9.8 0.1 2.5 2 2 0 2 2 2 0 Trm112p-like protein zf-RING_4 PF14570.1 EPX71236.1 - 0.37 10.4 6.9 4.3 6.9 0.0 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 EPX71236.1 - 0.92 9.5 8.9 0.15 12.0 0.8 2.4 2 1 0 2 2 2 0 Zinc ribbon domain C1_4 PF07975.7 EPX71236.1 - 2.1 8.4 7.8 2.7 8.0 0.8 2.3 1 1 2 3 3 3 0 TFIIH C1-like domain HypA PF01155.14 EPX71236.1 - 2.9 7.5 6.7 0.22 11.2 0.5 1.8 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family A2L_zn_ribbon PF08792.5 EPX71236.1 - 3.2 7.3 10.7 1.3 8.5 3.7 2.7 2 1 0 2 2 2 0 A2L zinc ribbon domain Autophagy_N PF03986.8 EPX71237.1 - 7.8e-35 119.7 0.2 1.1e-34 119.3 0.1 1.2 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EPX71237.1 - 6.6e-23 80.6 0.1 1.6e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EPX71237.1 - 2.6e-12 45.6 3.9 5.9e-12 44.4 2.7 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal SHS2_Rpb7-N PF03876.12 EPX71238.1 - 8.3e-11 41.8 0.0 1.6e-10 40.9 0.0 1.5 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EPX71238.1 - 0.016 15.3 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain Mago_nashi PF02792.9 EPX71239.1 - 3.2e-83 276.5 0.8 3.6e-83 276.3 0.6 1.0 1 0 0 1 1 1 1 Mago nashi protein DNA_Packaging PF11053.3 EPX71239.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 1 0 1 1 1 0 Terminase DNA packaging enzyme EAP30 PF04157.11 EPX71240.1 - 9.5e-39 132.8 3.0 9.5e-39 132.8 2.1 1.8 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EPX71240.1 - 3.6e-24 84.3 0.1 6.5e-24 83.5 0.1 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 EPX71240.1 - 0.00034 19.6 0.3 0.00034 19.6 0.2 2.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Interfer-bind PF09294.5 EPX71240.1 - 0.0032 17.4 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III zf-ribbon_3 PF13248.1 EPX71240.1 - 0.0035 16.4 1.0 0.0035 16.4 0.7 2.2 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 EPX71240.1 - 0.004 16.9 0.6 0.004 16.9 0.4 2.1 1 1 1 2 2 2 2 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 EPX71240.1 - 0.33 10.5 4.8 3.2 7.3 0.2 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Rubredoxin PF00301.15 EPX71240.1 - 0.43 10.4 4.8 11 6.0 0.5 2.4 2 0 0 2 2 2 0 Rubredoxin zinc_ribbon_2 PF13240.1 EPX71240.1 - 1.2 8.7 5.8 1 8.9 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TFIID_90kDa PF04494.10 EPX71240.1 - 2 8.4 7.1 0.14 12.2 0.7 2.2 3 0 0 3 3 3 0 WD40 associated region in TFIID subunit GCC2_GCC3 PF07699.8 EPX71240.1 - 2.9 7.5 8.1 0.97 9.0 0.8 2.4 2 0 0 2 2 2 0 GCC2 and GCC3 V-SNARE_C PF12352.3 EPX71241.1 - 3.7e-16 58.9 4.3 3.7e-16 58.9 3.0 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 EPX71241.1 - 1.5e-13 50.6 0.7 2.7e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus YqjK PF13997.1 EPX71241.1 - 0.027 14.6 2.2 0.028 14.5 0.0 2.2 3 0 0 3 3 3 0 YqjK-like protein Prominin PF05478.6 EPX71241.1 - 0.086 10.3 0.1 0.24 8.9 0.0 1.6 1 1 0 1 1 1 0 Prominin DASH_Dad4 PF08650.5 EPX71242.1 - 1.9e-31 107.7 8.7 2.1e-31 107.6 6.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 EPX71242.1 - 0.003 17.2 2.3 0.0039 16.8 1.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 SNARE PF05739.14 EPX71242.1 - 0.044 13.4 0.5 0.089 12.4 0.1 1.7 1 1 1 2 2 2 0 SNARE domain CSTF2_hinge PF14327.1 EPX71243.1 - 8.8e-21 73.7 1.0 8.8e-21 73.7 0.7 2.4 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EPX71243.1 - 8.7e-18 63.7 0.0 1.5e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71243.1 - 2.6e-09 36.9 0.0 6.6e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EPX71243.1 - 1.6e-07 30.4 4.1 4.3e-07 29.1 2.8 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 EPX71243.1 - 0.00032 20.4 0.0 0.00064 19.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 EPX71243.1 - 0.0081 15.6 0.0 0.099 12.1 0.0 2.5 2 0 0 2 2 2 1 Sporulation protein family 7 Sybindin PF04099.7 EPX71244.1 - 1.4e-50 170.7 0.1 1.5e-50 170.5 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EPX71244.1 - 3.1e-08 33.5 0.5 4.6e-08 32.9 0.4 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region ACOX PF01756.14 EPX71244.1 - 0.13 11.6 0.1 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA oxidase dsrm PF00035.20 EPX71245.1 - 4.5e-07 30.3 0.0 1.2e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 EPX71245.1 - 1.6e-06 28.0 0.0 1.2e-05 25.2 0.0 2.4 2 1 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EPX71245.1 - 6.2e-05 23.4 0.0 0.0003 21.2 0.0 2.1 2 1 0 2 2 2 1 Ribonuclease III domain DND1_DSRM PF14709.1 EPX71245.1 - 0.028 14.7 0.0 0.083 13.1 0.0 1.9 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Sterol-sensing PF12349.3 EPX71246.1 - 8.4e-33 112.9 9.3 1.7e-32 111.9 6.5 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation WD40 PF00400.27 EPX71246.1 - 0.03 14.1 0.1 0.24 11.3 0.1 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat BBS2_N PF14781.1 EPX71246.1 - 0.16 11.6 0.1 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Nup160 PF11715.3 EPX71247.1 - 2.4e-62 210.8 5.4 3.4e-62 210.3 3.7 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 EPX71247.1 - 0.021 14.7 0.0 0.059 13.2 0.0 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat Fe-S_biosyn PF01521.15 EPX71248.1 - 3.2e-14 52.8 0.0 4.8e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis ATP-synt_F PF01990.12 EPX71249.1 - 1.9e-28 98.6 0.4 2.2e-28 98.4 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Ins134_P3_kin PF05770.6 EPX71249.1 - 0.029 13.3 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase GrpE PF01025.14 EPX71250.1 - 7.9e-48 162.1 4.9 1e-47 161.8 3.4 1.1 1 0 0 1 1 1 1 GrpE Fez1 PF06818.10 EPX71250.1 - 0.00022 21.3 1.9 0.0003 20.8 1.3 1.2 1 0 0 1 1 1 1 Fez1 DUF812 PF05667.6 EPX71250.1 - 0.0023 16.5 3.5 0.0027 16.2 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Pro_dh PF01619.13 EPX71250.1 - 0.022 13.7 1.1 0.033 13.1 0.8 1.2 1 0 0 1 1 1 0 Proline dehydrogenase Mit_KHE1 PF10173.4 EPX71250.1 - 0.028 14.2 0.3 0.034 13.9 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related OmpH PF03938.9 EPX71250.1 - 0.031 14.2 5.8 0.042 13.7 4.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.8 EPX71250.1 - 0.055 12.5 1.2 0.068 12.2 0.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4446 PF14584.1 EPX71250.1 - 0.063 13.0 6.6 0.39 10.5 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Hph PF13694.1 EPX71250.1 - 0.067 13.2 2.1 0.085 12.8 1.4 1.1 1 0 0 1 1 1 0 Sec63/Sec62 complex-interacting family Atg14 PF10186.4 EPX71250.1 - 0.19 10.6 5.3 0.24 10.3 3.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 EPX71250.1 - 1.2 9.0 4.3 4.3 7.3 0.3 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 EPX71250.1 - 1.8 8.4 12.4 0.13 12.1 4.6 2.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EPX71250.1 - 1.9 8.0 6.7 3.4 7.2 4.6 1.5 1 1 0 1 1 1 0 IncA protein RabGAP-TBC PF00566.13 EPX71251.1 - 1.5e-48 165.1 0.8 3.9e-48 163.7 0.6 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 EPX71251.1 - 7.2e-06 26.0 4.4 8.2e-05 22.6 0.3 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EPX71251.1 - 1.5e-05 24.5 1.5 0.13 12.2 0.1 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EPX71251.1 - 2.9e-05 23.0 2.3 0.071 12.4 0.3 3.8 3 0 0 3 3 3 2 EF hand Prefoldin PF02996.12 EPX71252.1 - 2.2e-25 88.6 1.3 4.8e-25 87.5 0.2 1.8 1 1 1 2 2 2 2 Prefoldin subunit Cep57_MT_bd PF06657.8 EPX71252.1 - 8e-06 25.7 0.3 0.03 14.2 0.0 2.3 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 Prefoldin_2 PF01920.15 EPX71252.1 - 3.2e-05 23.6 1.0 0.022 14.5 0.0 2.2 2 0 0 2 2 2 2 Prefoldin subunit ZapA PF05164.8 EPX71252.1 - 0.0025 17.7 0.2 0.0059 16.5 0.1 1.7 1 1 1 2 2 2 1 Cell division protein ZapA COG5 PF10392.4 EPX71252.1 - 0.0034 17.3 1.5 0.59 10.0 0.1 2.3 2 0 0 2 2 2 2 Golgi transport complex subunit 5 DUF1192 PF06698.6 EPX71252.1 - 0.0084 15.9 0.3 0.17 11.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Streptin-Immun PF11083.3 EPX71252.1 - 0.054 13.4 0.9 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Reo_sigmaC PF04582.7 EPX71252.1 - 0.074 12.2 0.7 1.5 7.9 0.1 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IL6 PF00489.12 EPX71252.1 - 0.13 11.8 1.0 0.33 10.5 0.1 1.9 2 1 0 2 2 2 0 Interleukin-6/G-CSF/MGF family Rad21_Rec8_N PF04825.8 EPX71252.1 - 0.16 11.9 0.9 0.78 9.7 0.2 2.0 2 0 0 2 2 2 0 N terminus of Rad21 / Rec8 like protein BLOC1_2 PF10046.4 EPX71252.1 - 0.45 10.6 3.9 5 7.3 0.1 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FbpA PF05833.6 EPX71252.1 - 0.51 8.8 4.3 3.3 6.1 0.5 2.0 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) RPN7 PF10602.4 EPX71253.1 - 1.8e-45 154.5 1.6 3.2e-45 153.6 1.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EPX71253.1 - 1.4e-15 57.5 0.6 2.6e-14 53.4 0.0 2.6 2 1 0 2 2 2 1 PCI domain TPR_2 PF07719.12 EPX71253.1 - 8.2e-05 22.2 0.5 0.069 13.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPX71253.1 - 0.001 18.5 0.7 0.64 9.7 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPX71253.1 - 0.0023 18.4 0.0 0.11 13.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPX71253.1 - 0.0035 16.9 1.0 0.1 12.2 0.6 2.5 1 1 0 1 1 1 1 TPR repeat TPR_12 PF13424.1 EPX71253.1 - 0.006 16.4 1.1 1.2 9.0 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPX71253.1 - 0.0082 15.8 0.1 3.3 7.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Nudix_N PF12535.3 EPX71253.1 - 0.026 13.9 0.2 0.078 12.4 0.0 2.0 2 0 0 2 2 2 0 Hydrolase of X-linked nucleoside diphosphate N terminal TPR_10 PF13374.1 EPX71253.1 - 0.089 12.7 0.2 0.82 9.6 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EPX71253.1 - 0.2 11.1 3.6 0.49 9.8 0.5 2.5 3 0 0 3 3 3 0 Foie gras liver health family 1 NAD_Gly3P_dh_N PF01210.18 EPX71255.1 - 9.9e-58 194.3 0.0 1.3e-56 190.7 0.0 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EPX71255.1 - 1.6e-50 170.6 0.1 3.5e-50 169.6 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EPX71255.1 - 6.8e-05 23.2 0.1 0.00036 20.8 0.1 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.4 EPX71255.1 - 0.0043 16.7 0.3 2.4 7.9 0.0 2.7 3 0 0 3 3 3 2 Rossmann-like domain zf-LYAR PF08790.6 EPX71256.1 - 8.3e-15 54.1 3.5 1.9e-14 53.0 2.4 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Raftlin PF15250.1 EPX71256.1 - 0.42 9.0 13.5 0.51 8.8 9.4 1.1 1 0 0 1 1 1 0 Raftlin Ebola_NP PF05505.7 EPX71256.1 - 0.53 8.2 9.8 0.56 8.2 6.8 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein IBR PF01485.16 EPX71256.1 - 2.1 8.2 8.1 6.1 6.7 5.6 1.9 1 0 0 1 1 1 0 IBR domain GCD14 PF08704.5 EPX71256.1 - 5.6 6.3 8.5 10 5.5 5.9 1.5 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PWWP PF00855.12 EPX71257.1 - 2.4e-15 56.4 0.2 2.4e-15 56.4 0.1 3.0 3 1 0 3 3 3 1 PWWP domain Med26 PF08711.6 EPX71257.1 - 0.00026 20.4 0.1 0.00051 19.5 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CPSase_L_D2 PF02786.12 EPX71258.1 - 3e-110 366.4 0.1 2.6e-84 281.7 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EPX71258.1 - 2.7e-40 136.9 0.1 6.6e-40 135.6 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EPX71258.1 - 2.8e-37 128.2 0.1 6.9e-20 71.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 EPX71258.1 - 5.2e-35 119.8 0.0 6.4e-17 61.6 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EPX71258.1 - 1.4e-23 83.1 0.0 6.4e-11 41.5 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EPX71258.1 - 1.3e-19 70.1 0.0 1.6e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EPX71258.1 - 3e-16 59.4 0.3 5.2e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EPX71258.1 - 1.5e-10 40.9 0.0 1.6e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 EPX71258.1 - 4.1e-05 23.2 1.0 0.25 10.8 0.0 3.0 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EPX71258.1 - 0.00037 19.7 0.0 0.074 12.2 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain Epimerase PF01370.16 EPX71258.1 - 0.025 14.0 0.1 0.17 11.3 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 EPX71259.1 - 1.7e-97 325.5 1.9 1.7e-97 325.5 1.3 1.7 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPX71259.1 - 1.9e-40 137.1 1.6 1.1e-39 134.6 0.1 2.6 3 1 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EPX71259.1 - 0.00016 21.2 1.5 0.00016 21.2 1.0 2.7 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EPX71259.1 - 0.025 14.2 0.3 0.98 9.1 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.22 EPX71260.1 - 2.8e-39 134.4 0.0 5.1e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EPX71260.1 - 1.5e-26 92.2 0.0 3.1e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EPX71260.1 - 9.8e-21 73.4 0.0 2.3e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPX71260.1 - 3e-10 40.0 0.0 7.2e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 EPX71260.1 - 2.2e-06 28.1 0.0 6.4e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein EFG_II PF14492.1 EPX71260.1 - 0.00032 20.4 0.0 0.001 18.8 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 EPX71260.1 - 0.002 17.3 0.0 0.0071 15.5 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EPX71260.1 - 0.02 14.2 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 Ras family Snf7 PF03357.16 EPX71262.1 - 2.2e-27 95.4 6.4 2.6e-27 95.2 4.5 1.0 1 0 0 1 1 1 1 Snf7 WD40 PF00400.27 EPX71263.1 - 7.8e-44 146.0 22.1 1.8e-09 37.1 0.3 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF1500 PF07389.7 EPX71263.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) IKI3 PF04762.7 EPX71263.1 - 0.12 10.1 5.8 0.24 9.1 1.3 2.1 2 0 0 2 2 2 0 IKI3 family IMS PF00817.15 EPX71264.1 - 1.2e-39 135.4 0.1 2.7e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EPX71264.1 - 1.7e-11 44.1 0.0 3.5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 EPX71264.1 - 1.9e-08 34.3 0.1 7.8e-08 32.3 0.1 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF4414 PF14377.1 EPX71264.1 - 8e-07 28.9 15.6 0.00047 20.0 4.8 4.2 2 1 2 4 4 4 3 Domain of unknown function (DUF4414) PTCB-BRCT PF12738.2 EPX71264.1 - 3.4e-05 23.5 0.0 0.00011 22.0 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 EPX71264.1 - 0.012 15.6 0.0 0.047 13.7 0.0 2.2 1 0 0 1 1 1 0 IMS family HHH motif DUF1805 PF08827.6 EPX71264.1 - 0.043 13.6 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) FKBP_C PF00254.23 EPX71265.1 - 6.5e-29 99.8 0.3 2.7e-28 97.7 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Hid1 PF12722.2 EPX71265.1 - 1.1 6.8 14.6 1.3 6.5 10.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 EPX71265.1 - 1.7 6.5 26.7 3.8 5.4 18.5 1.6 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 EPX71265.1 - 2.5 6.3 42.0 4.2 5.6 29.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pil1 PF13805.1 EPX71266.1 - 1e-47 162.5 0.2 1.7e-47 161.8 0.1 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 E2R135 PF11570.3 EPX71266.1 - 0.049 13.7 1.7 0.12 12.4 0.5 2.0 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 Tim54 PF11711.3 EPX71267.1 - 1.2e-63 214.9 0.0 1.6e-61 208.0 0.0 2.0 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 RP-C_C PF11800.3 EPX71267.1 - 0.095 12.3 1.4 0.17 11.5 0.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Kei1 PF08552.6 EPX71267.1 - 1.1 8.8 2.8 1.8 8.1 1.9 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DnaJ PF00226.26 EPX71268.1 - 1.4e-28 98.4 0.4 2.3e-28 97.7 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EPX71268.1 - 2.4e-15 56.3 8.2 4.1e-15 55.5 5.7 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EPX71268.1 - 1.6e-12 47.1 0.1 7.8e-12 44.9 0.0 2.1 3 0 0 3 3 3 1 DnaJ C terminal domain HypA PF01155.14 EPX71268.1 - 0.064 12.9 3.0 1.8 8.2 0.7 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 EPX71268.1 - 1.2 9.5 9.8 3.6 7.9 0.4 3.6 2 1 2 4 4 4 0 Restriction alleviation protein Lar zf-RING_3 PF14369.1 EPX71268.1 - 8.2 6.5 11.1 12 5.9 0.7 3.0 2 1 0 2 2 2 0 zinc-finger Pkinase PF00069.20 EPX71269.1 - 6.7e-34 117.2 0.0 9e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71269.1 - 3.3e-12 46.0 0.0 4.2e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX71269.1 - 0.00076 19.2 0.0 1.2 8.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EPX71269.1 - 0.11 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RNase_T PF00929.19 EPX71270.1 - 4.8e-33 114.7 0.0 5.4e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Exonuclease RNase_H2-Ydr279 PF09468.5 EPX71271.1 - 1.5e-50 172.1 0.0 1.7e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) WTF PF03303.8 EPX71272.1 - 5.4 6.3 5.5 1.1 8.5 1.4 1.8 2 1 0 2 2 2 0 WTF protein SUN PF03856.8 EPX71273.1 - 5.4e-98 327.2 14.1 7.7e-98 326.7 9.8 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Aldedh PF00171.17 EPX71274.1 - 3e-158 526.9 0.1 3.4e-158 526.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EPX71274.1 - 0.0045 16.2 0.0 0.013 14.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) FmrO PF07091.6 EPX71274.1 - 0.14 11.1 0.2 0.23 10.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Gaa1 PF04114.9 EPX71275.1 - 1.1e-113 380.6 12.2 5.9e-111 371.6 1.1 2.2 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component CoA_binding_3 PF13727.1 EPX71275.1 - 8 6.2 7.7 0.51 10.1 0.8 2.3 1 1 1 2 2 2 0 CoA-binding domain SGT1 PF07093.6 EPX71276.1 - 1.7e-104 350.3 27.2 1.8e-95 320.5 0.1 2.0 1 1 1 2 2 2 2 SGT1 protein FliD_C PF07195.7 EPX71276.1 - 0.97 8.6 10.4 6.1 6.0 0.7 3.0 2 2 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Pyr_redox_dim PF02852.17 EPX71277.1 - 7.6e-41 138.5 1.4 1.2e-40 137.9 0.2 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EPX71277.1 - 2.9e-38 131.7 0.0 6.1e-38 130.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPX71277.1 - 2.9e-17 62.8 5.9 4.3e-16 59.0 0.2 3.2 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPX71277.1 - 5.3e-12 45.5 0.2 2.8e-10 39.8 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPX71277.1 - 1.5e-09 37.7 1.4 0.0006 19.7 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPX71277.1 - 2.3e-08 34.3 0.2 2.7e-05 24.3 0.0 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPX71277.1 - 2.8e-08 33.0 7.2 3.4e-07 29.4 5.0 2.5 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EPX71277.1 - 1.6e-05 23.9 3.5 6e-05 22.0 0.8 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EPX71277.1 - 0.00017 20.7 9.2 0.055 12.5 0.6 3.5 2 1 2 4 4 4 2 FAD binding domain Thi4 PF01946.12 EPX71277.1 - 0.00034 19.7 5.4 0.001 18.2 0.1 2.5 1 1 1 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EPX71277.1 - 0.00065 18.7 0.0 0.16 10.8 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EPX71277.1 - 0.0011 17.5 9.5 0.019 13.4 0.2 3.7 3 1 1 4 4 4 2 HI0933-like protein DAO PF01266.19 EPX71277.1 - 0.0018 17.2 4.8 1.2 8.0 1.2 3.3 2 1 1 3 3 3 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EPX71277.1 - 0.041 13.4 1.2 0.21 11.1 0.1 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EPX71277.1 - 0.06 12.9 0.3 0.17 11.5 0.2 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RrnaAD PF00398.15 EPX71278.1 - 1.1e-39 136.1 0.0 1.3e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TetR_N PF00440.18 EPX71278.1 - 0.11 12.0 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Acetyltransf_1 PF00583.19 EPX71279.1 - 8.8e-15 54.5 0.0 1.4e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPX71279.1 - 1.4e-10 41.1 0.1 2.5e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPX71279.1 - 8.8e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPX71279.1 - 1.5e-06 28.3 0.0 2.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPX71279.1 - 4.5e-05 23.6 0.0 5.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPX71279.1 - 0.00046 20.1 0.0 0.00059 19.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPX71279.1 - 0.016 15.0 0.0 0.024 14.5 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4557 PF15101.1 EPX71280.1 - 0.051 13.4 0.0 0.057 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SPDY PF03771.11 EPX71280.1 - 0.25 10.8 1.3 2.7 7.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF317) JmjC PF02373.17 EPX71281.1 - 3.2e-40 136.9 0.2 1.3e-39 135.0 0.1 2.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 EPX71281.1 - 6.1e-15 54.4 2.3 1.7e-14 53.0 1.6 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EPX71281.1 - 4.1e-12 45.9 10.0 1.2e-11 44.4 6.9 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger ARID PF01388.16 EPX71281.1 - 6.8e-07 29.0 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain TAFII28 PF04719.9 EPX71282.1 - 1.3e-35 121.0 0.0 1.9e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Glyco_hydro_31 PF01055.21 EPX71283.1 - 2.6e-147 491.2 1.0 3.5e-147 490.8 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EPX71283.1 - 3e-22 78.2 0.3 1e-21 76.5 0.2 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like NPCC PF08058.6 EPX71284.1 - 6e-24 84.5 0.0 8.5e-15 54.8 0.0 2.2 1 1 1 2 2 2 2 Nuclear pore complex component Spore_III_AF PF09581.5 EPX71284.1 - 0.044 13.6 0.4 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) FLILHELTA PF10306.4 EPX71285.1 - 5.8e-21 74.3 0.0 7.9e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA RRM_1 PF00076.17 EPX71287.1 - 4e-32 109.6 0.3 8.2e-15 54.1 0.0 4.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71287.1 - 2.7e-25 88.1 0.0 5e-08 32.7 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX71287.1 - 2e-14 53.1 1.1 7.3e-08 32.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L1 PF00687.16 EPX71288.1 - 3.6e-23 82.0 0.0 4.3e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Voldacs PF03517.8 EPX71289.1 - 2.2e-22 79.3 0.2 1.8e-21 76.4 0.2 2.3 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling FNIP_N PF14636.1 EPX71289.1 - 0.089 13.2 0.3 0.17 12.3 0.0 1.6 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Hid1 PF12722.2 EPX71290.1 - 5e-140 467.9 26.3 6e-140 467.6 18.2 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EPX71290.1 - 2.6e-56 191.1 0.0 9.4e-56 189.2 0.0 1.8 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein tRNA-synt_1c PF00749.16 EPX71291.1 - 5.4e-104 347.2 0.0 7.4e-104 346.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EPX71291.1 - 6.4e-40 136.6 0.5 1.6e-39 135.3 0.4 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EPX71291.1 - 2.8e-08 34.1 0.4 8.1e-08 32.6 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPX71291.1 - 0.00022 21.1 0.0 0.00065 19.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EPX71291.1 - 0.0064 15.6 0.2 0.022 13.8 0.1 1.7 1 1 1 2 2 2 1 tRNA synthetases class I (C) catalytic domain XRN_N PF03159.13 EPX71292.1 - 2.4e-105 351.1 0.2 5e-105 350.1 0.1 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus GTP_cyclohydroI PF01227.17 EPX71293.1 - 8e-76 253.3 0.2 9.6e-76 253.0 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EPX71293.1 - 0.00069 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein OmpH PF03938.9 EPX71293.1 - 0.11 12.4 0.7 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TPR_11 PF13414.1 EPX71294.1 - 3.8e-10 39.2 0.0 9.1e-09 34.8 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 EPX71294.1 - 6.9e-07 29.1 0.0 0.00041 20.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPX71294.1 - 1.1e-05 24.9 0.0 0.63 10.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPX71294.1 - 1.5e-05 24.4 0.0 0.28 11.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPX71294.1 - 2e-05 23.9 0.0 1.6 8.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat DnaJ PF00226.26 EPX71294.1 - 6e-05 22.7 0.0 0.00022 20.9 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain UBA PF00627.26 EPX71294.1 - 7.1e-05 22.5 0.0 0.00028 20.6 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain Apc3 PF12895.2 EPX71294.1 - 0.0052 16.8 0.1 0.15 12.2 0.0 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EPX71294.1 - 0.099 13.3 0.0 59 4.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TP6A_N PF04406.9 EPX71295.1 - 1.2e-21 76.1 0.0 2.8e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 EPX71295.1 - 0.00051 19.9 0.0 0.0014 18.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2399) DnaJ_CXXCXGXG PF00684.14 EPX71296.1 - 0.0074 16.3 9.1 0.57 10.2 1.0 2.5 2 1 0 2 2 2 2 DnaJ central domain Med13_C PF06333.7 EPX71296.1 - 2 6.8 5.7 2.4 6.5 4.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal IPP-2 PF04979.9 EPX71297.1 - 1.1e-05 25.6 1.0 1.1e-05 25.6 0.7 3.1 4 0 0 4 4 4 2 Protein phosphatase inhibitor 2 (IPP-2) EMP24_GP25L PF01105.19 EPX71298.1 - 3.3e-40 137.7 0.4 3.8e-40 137.5 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4302 PF14135.1 EPX71298.1 - 0.096 12.0 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) Peptidase_C48 PF02902.14 EPX71299.1 - 1.7e-49 168.3 2.7 2.6e-49 167.7 1.8 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Helicase_C_3 PF13625.1 EPX71300.1 - 1e-28 99.6 0.0 4.8e-28 97.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX71300.1 - 2.8e-15 56.6 0.3 2.6e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPX71300.1 - 1.3e-11 43.8 0.1 2.3e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPX71300.1 - 2e-10 40.3 0.0 4.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TehB PF03848.9 EPX71301.1 - 0.035 13.2 0.0 0.042 13.0 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_23 PF13489.1 EPX71302.1 - 2.6e-07 30.4 0.0 4.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX71302.1 - 6.6e-05 23.3 0.0 0.00047 20.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX71302.1 - 0.00087 19.7 0.0 0.0085 16.5 0.0 2.1 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX71302.1 - 0.00092 19.7 0.0 0.003 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX71302.1 - 0.0014 18.2 0.0 0.72 9.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EPX71302.1 - 0.0022 18.3 0.0 0.0092 16.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Reprolysin_5 PF13688.1 EPX71303.1 - 1.1e-26 93.9 0.1 1.1e-26 93.9 0.0 2.8 3 1 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EPX71303.1 - 5.3e-24 84.9 0.2 3.4e-17 62.6 0.0 2.8 3 0 0 3 3 3 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EPX71303.1 - 1.2e-19 71.0 0.0 7.7e-19 68.3 0.0 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EPX71303.1 - 4.4e-19 68.4 32.3 4.4e-19 68.4 22.4 4.2 3 1 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.1 EPX71303.1 - 1.3e-05 25.6 0.5 4.6e-05 23.9 0.0 2.3 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 EPX71303.1 - 1.4e-05 24.8 0.4 1.4e-05 24.8 0.3 3.0 1 1 1 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M10 PF00413.19 EPX71303.1 - 0.007 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.8 EPX71303.1 - 0.036 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Ribosomal_L3 PF00297.17 EPX71304.1 - 1.2e-120 401.8 5.9 1.4e-120 401.5 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DBR1 PF05011.8 EPX71305.1 - 6.5e-36 123.3 1.5 9.5e-36 122.8 0.1 1.9 3 0 0 3 3 3 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EPX71305.1 - 3.7e-14 52.5 0.6 5.9e-14 51.9 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UvdE PF03851.9 EPX71306.1 - 0.029 13.3 0.2 0.07 12.1 0.0 1.7 1 1 1 2 2 2 0 UV-endonuclease UvdE Ku_N PF03731.10 EPX71306.1 - 0.088 12.2 2.8 0.94 8.8 0.4 2.5 1 1 0 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain Nup188 PF10487.4 EPX71306.1 - 0.11 10.3 6.5 0.13 10.1 4.5 1.0 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 Prominin PF05478.6 EPX71306.1 - 0.13 9.7 6.0 0.32 8.4 4.2 1.6 1 1 0 1 1 1 0 Prominin AAA PF00004.24 EPX71307.1 - 1.3e-49 167.7 0.0 5.5e-45 152.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPX71307.1 - 2.7e-05 23.3 0.0 4.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPX71307.1 - 6e-05 23.1 0.1 0.00036 20.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EPX71307.1 - 9.6e-05 23.1 0.0 0.00045 21.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPX71307.1 - 0.00029 20.9 0.4 0.0024 18.0 0.0 2.6 2 1 1 3 3 2 1 AAA domain RNA_helicase PF00910.17 EPX71307.1 - 0.00046 20.3 0.0 0.0017 18.4 0.0 2.0 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.8 EPX71307.1 - 0.00068 18.4 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EPX71307.1 - 0.0012 18.5 0.0 0.0052 16.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPX71307.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EPX71307.1 - 0.0016 18.3 0.0 0.0088 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPX71307.1 - 0.0021 17.5 0.6 0.028 13.7 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPX71307.1 - 0.0025 17.5 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain Vps4_C PF09336.5 EPX71307.1 - 0.0031 17.3 0.0 0.079 12.8 0.0 2.9 2 1 1 3 3 3 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.12 EPX71307.1 - 0.0033 16.8 0.1 0.0071 15.7 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EPX71307.1 - 0.0098 15.0 0.1 0.024 13.7 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EPX71307.1 - 0.011 15.5 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPX71307.1 - 0.012 15.8 0.0 0.053 13.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EPX71307.1 - 0.016 14.7 0.5 0.035 13.6 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EPX71307.1 - 0.03 13.9 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EPX71307.1 - 0.033 13.0 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 EPX71307.1 - 0.044 12.9 0.0 0.096 11.7 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 EPX71307.1 - 0.052 12.7 0.1 0.17 11.0 0.1 1.8 2 0 0 2 2 1 0 PhoH-like protein DUF815 PF05673.8 EPX71307.1 - 0.091 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 EPX71307.1 - 0.096 12.3 0.1 0.47 10.0 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EPX71307.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 EPX71308.1 - 1.6e-25 89.5 4.6 3.8e-25 88.2 3.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_4 PF13637.1 EPX71309.1 - 6.2e-12 45.6 1.3 1.7e-06 28.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPX71309.1 - 5.6e-11 42.6 0.3 3.6e-08 33.6 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPX71309.1 - 7.6e-10 38.7 0.1 4.5e-05 23.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EPX71309.1 - 1.8e-09 36.9 1.2 0.00016 21.3 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EPX71309.1 - 2.2e-06 27.3 0.2 0.032 14.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Na_H_Exchanger PF00999.16 EPX71310.1 - 4.4e-61 206.5 41.4 6.1e-61 206.0 28.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PCIF1_WW PF12237.3 EPX71310.1 - 0.053 12.8 0.2 0.11 11.7 0.2 1.4 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain Pkinase PF00069.20 EPX71311.1 - 7.8e-73 244.8 0.0 9.1e-73 244.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71311.1 - 7.8e-34 116.9 0.0 1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX71311.1 - 5.6e-07 28.7 0.0 8.3e-07 28.2 0.0 1.3 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EPX71311.1 - 0.00068 19.0 0.1 0.0022 17.3 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 EPX71311.1 - 0.0013 18.5 0.0 0.028 14.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EPX71311.1 - 0.0065 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 EPX71312.1 - 1.5e-47 157.8 7.5 5.7e-10 38.6 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EPX71312.1 - 5.4e-07 28.1 12.2 0.17 9.9 0.5 4.8 3 2 2 5 5 5 4 Nucleoporin Nup120/160 CIMR PF00878.13 EPX71312.1 - 0.009 15.7 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat APG6 PF04111.7 EPX71312.1 - 0.019 14.0 4.1 0.032 13.2 2.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Ammonium_transp PF00909.16 EPX71313.1 - 1.6e-114 382.4 28.8 1.9e-114 382.2 19.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family UPF0122 PF04297.9 EPX71314.1 - 0.034 14.1 1.8 0.036 14.0 0.5 1.6 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Adeno_E4_34 PF04528.8 EPX71314.1 - 0.086 12.4 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region CheZ PF04344.8 EPX71314.1 - 1.2 8.7 4.6 2.3 7.8 1.0 2.0 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ DUF3134 PF11332.3 EPX71314.1 - 8.3 6.6 6.8 0.65 10.1 1.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3134) Complex1_LYR PF05347.10 EPX71315.1 - 3.8e-08 32.9 2.2 5.1e-08 32.5 1.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPX71315.1 - 2.8e-05 24.2 3.3 3.6e-05 23.8 2.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like HSP70 PF00012.15 EPX71316.1 - 1.3e-260 865.5 11.2 1.5e-260 865.3 7.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPX71316.1 - 3.6e-15 55.4 2.6 4.3e-13 48.5 0.5 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EPX71316.1 - 0.0049 16.5 0.1 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EPX71316.1 - 0.019 14.7 7.9 0.55 10.0 0.2 4.2 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.13 EPX71316.1 - 0.022 13.8 2.0 1.2 8.1 0.1 3.2 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase Kinesin PF00225.18 EPX71317.1 - 3.7e-103 344.7 0.1 3.7e-103 344.7 0.1 2.3 2 1 0 2 2 2 1 Kinesin motor domain Nbl1_Borealin_N PF10444.4 EPX71317.1 - 0.0064 15.8 1.3 0.0064 15.8 0.9 4.0 4 1 2 6 6 6 2 Nbl1 / Borealin N terminal G_glu_transpept PF01019.16 EPX71318.1 - 3.1e-170 567.0 0.0 3.6e-170 566.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Actin PF00022.14 EPX71319.1 - 1.5e-29 102.6 0.0 1.9e-28 99.0 0.0 2.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPX71319.1 - 0.00034 19.3 0.0 0.41 9.1 0.0 2.7 2 1 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.3 EPX71319.1 - 0.077 11.8 0.0 1 8.1 0.0 2.1 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Paf1 PF03985.8 EPX71320.1 - 3.3e-96 322.7 11.2 3.3e-96 322.7 7.8 1.9 1 1 1 2 2 2 1 Paf1 GAGA_bind PF06217.7 EPX71320.1 - 0.25 11.2 8.7 0.45 10.4 6.0 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Macoilin PF09726.4 EPX71320.1 - 2.3 6.4 11.4 3.9 5.6 7.9 1.3 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 EPX71320.1 - 8.1 6.2 10.3 63 3.3 0.0 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_S9 PF00380.14 EPX71321.1 - 1.6e-38 131.6 0.6 1.8e-38 131.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Exo70 PF03081.10 EPX71321.1 - 0.13 11.0 0.3 0.16 10.6 0.2 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Ribosomal_L13e PF01294.13 EPX71322.1 - 3.5e-71 238.3 4.3 4.4e-71 238.0 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L30 PF00327.15 EPX71323.1 - 3e-19 68.3 0.8 9.4e-19 66.7 0.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 EPX71323.1 - 1.3e-17 63.5 11.7 1.3e-17 63.5 8.1 2.3 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Rad9 PF04139.8 EPX71324.1 - 6.8e-91 303.8 6.4 8.2e-91 303.5 4.4 1.1 1 0 0 1 1 1 1 Rad9 TRAUB PF08164.7 EPX71325.1 - 2.3e-29 101.3 1.8 1.9e-28 98.3 0.4 2.7 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EPX71325.1 - 1.9e-22 79.8 1.8 1.9e-22 79.8 1.2 3.5 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor Chromo_shadow PF01393.14 EPX71326.1 - 5.7e-29 99.7 0.0 1.1e-26 92.3 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 EPX71326.1 - 4.1e-13 48.7 0.5 4.1e-13 48.7 0.4 2.8 2 1 1 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain ArfGap PF01412.13 EPX71327.1 - 5.8e-41 138.9 0.3 1.2e-40 137.9 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Adap_comp_sub PF00928.16 EPX71328.1 - 9.2e-80 267.5 0.1 1.2e-79 267.1 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EPX71328.1 - 8.4e-14 51.4 0.2 1.6e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain EppA_BapA PF07268.6 EPX71328.1 - 0.0052 16.4 0.0 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 Exported protein precursor (EppA/BapA) Ribosomal_L23 PF00276.15 EPX71329.1 - 2.7e-21 75.3 0.1 4.9e-21 74.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L23 Arg_repressor PF01316.16 EPX71329.1 - 0.0051 16.3 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain DEAD PF00270.24 EPX71330.1 - 2.9e-48 163.5 0.2 9.9e-48 161.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX71330.1 - 6.8e-22 77.1 0.1 3.7e-20 71.5 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EPX71330.1 - 4e-20 71.3 1.1 1.1e-19 69.9 0.8 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 EPX71330.1 - 0.00049 19.9 0.0 0.00049 19.9 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Oligomerisation PF02410.10 EPX71331.1 - 8.1e-11 41.8 0.1 3.5e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Oligomerisation domain Nipped-B_C PF12830.2 EPX71332.1 - 5.3e-39 133.7 4.2 5.3e-39 133.7 2.9 3.3 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EPX71332.1 - 2e-06 27.6 7.0 1.5e-05 24.8 0.3 4.0 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 EPX71332.1 - 0.0095 16.1 0.3 1.5 9.1 0.0 4.0 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 EPX71332.1 - 0.042 13.9 5.2 6.8 7.0 0.0 6.0 6 0 0 6 6 6 0 HEAT repeat Mu-like_Com PF10122.4 EPX71332.1 - 0.11 11.5 0.3 0.71 8.9 0.0 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com Proteasome PF00227.21 EPX71333.1 - 4.6e-37 127.1 0.0 5.4e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L10 PF00466.15 EPX71334.1 - 0.043 13.7 0.0 0.097 12.6 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L10 Trm112p PF03966.11 EPX71335.1 - 3.5e-18 65.7 0.1 4.3e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein zinc_ribbon_5 PF13719.1 EPX71335.1 - 0.028 14.0 0.1 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EPX71335.1 - 0.27 10.9 1.6 0.4 10.4 0.0 2.1 3 0 0 3 3 3 0 zinc-ribbon domain PCI PF01399.22 EPX71336.1 - 1.3e-12 47.9 0.1 1.3e-12 47.9 0.1 2.5 2 1 0 2 2 2 1 PCI domain M11L PF11099.3 EPX71336.1 - 0.17 11.5 1.1 0.23 11.1 0.2 1.6 2 0 0 2 2 2 0 Apoptosis regulator M11L like Ribosomal_S19 PF00203.16 EPX71337.1 - 2.6e-23 81.4 0.0 3.2e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Dzip-like_N PF13815.1 EPX71338.1 - 1.7e-05 24.5 0.7 5.8e-05 22.8 0.5 1.8 1 1 0 1 1 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal MOR2-PAG1_N PF14222.1 EPX71338.1 - 0.32 9.6 4.8 0.33 9.5 3.3 1.0 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Gti1_Pac2 PF09729.4 EPX71340.1 - 4.4e-55 186.0 0.0 1.3e-54 184.5 0.0 1.9 1 1 0 1 1 1 1 Gti1/Pac2 family WD40 PF00400.27 EPX71341.1 - 6.8e-74 241.3 12.9 2e-12 46.4 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EPX71341.1 - 9.9e-26 89.7 10.6 1.6e-25 89.0 7.4 1.4 1 0 0 1 1 1 1 Tup N-terminal Nucleoporin_N PF08801.6 EPX71341.1 - 7.4e-10 38.1 2.2 1.3e-06 27.4 0.4 3.4 1 1 2 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 EPX71341.1 - 6.6e-06 25.6 1.4 17 5.1 0.0 6.9 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EPX71341.1 - 8.2e-06 25.6 0.0 0.018 14.7 0.0 3.3 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EPX71341.1 - 0.0084 14.4 0.1 0.61 8.3 0.0 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 EPX71341.1 - 0.056 12.0 0.1 45 2.4 0.0 3.7 1 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PTCRA PF15028.1 EPX71341.1 - 0.13 11.8 0.5 0.3 10.6 0.2 1.6 1 1 0 1 1 1 0 Pre-T-cell antigen receptor Prefoldin_2 PF01920.15 EPX71341.1 - 1.1 9.0 8.0 0.22 11.2 2.2 1.9 2 0 0 2 2 2 0 Prefoldin subunit DUF3384 PF11864.3 EPX71342.1 - 2.1e-53 181.4 16.4 4.4e-53 180.4 11.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EPX71342.1 - 2.1e-50 170.7 0.1 4.6e-50 169.6 0.1 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EPX71342.1 - 3.2e-23 82.3 2.7 3.2e-23 82.3 1.8 3.1 2 2 0 3 3 3 1 Tuberin Metallophos PF00149.23 EPX71343.1 - 1.6e-11 43.9 1.0 3.6e-11 42.8 0.7 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2317 PF10079.4 EPX71343.1 - 0.0058 15.2 0.0 0.0085 14.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2317) Vps55 PF04133.9 EPX71344.1 - 1.4e-36 124.8 4.4 1.6e-36 124.6 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Oxidored_q1 PF00361.15 EPX71344.1 - 0.0015 17.8 3.9 0.0026 17.0 2.2 1.7 1 1 0 1 1 1 1 NADH-Ubiquinone/plastoquinone (complex I), various chains DUF3321 PF11968.3 EPX71345.1 - 1e-68 231.2 0.0 1.3e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EPX71345.1 - 0.015 15.0 0.0 0.47 10.1 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain PGK PF00162.14 EPX71346.1 - 9.2e-149 495.1 1.9 1e-148 494.9 1.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase HEAT PF02985.17 EPX71347.1 - 4.1e-26 88.6 0.9 0.00011 21.9 0.1 10.9 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 EPX71347.1 - 2.5e-21 75.5 5.9 0.00022 21.6 0.1 9.4 9 1 1 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.1 EPX71347.1 - 1.9e-15 56.9 6.1 0.0051 17.0 0.1 7.8 6 2 3 9 9 9 5 HEAT repeats IBN_N PF03810.14 EPX71347.1 - 5.4e-12 45.4 0.7 1.4e-09 37.6 0.1 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EPX71347.1 - 1.8e-10 41.0 0.5 0.18 12.2 0.0 6.3 4 2 2 6 6 6 4 Vacuolar 14 Fab1-binding region UME PF08064.8 EPX71347.1 - 1.9e-06 27.7 0.0 0.45 10.4 0.0 4.7 3 1 1 4 4 4 2 UME (NUC010) domain MMS19_C PF12460.3 EPX71347.1 - 4.9e-06 25.5 10.3 4.8e-05 22.2 0.0 4.3 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 EPX71347.1 - 0.00012 21.4 0.1 3.3 7.0 0.0 5.3 4 2 0 4 4 4 1 CLASP N terminal Ipi1_N PF12333.3 EPX71347.1 - 0.00036 20.4 0.1 0.24 11.3 0.1 4.3 3 1 1 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation DUF2435 PF10363.4 EPX71347.1 - 0.046 13.6 1.3 12 5.8 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) Trs65 PF12735.2 EPX71348.1 - 1.2e-22 80.5 1.3 2.7e-22 79.4 0.9 1.6 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 DUF4504 PF14953.1 EPX71349.1 - 4.2e-09 36.1 1.1 1.7e-08 34.1 0.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4504) Pkinase PF00069.20 EPX71350.1 - 5.7e-67 225.6 0.1 1e-66 224.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71350.1 - 3.9e-31 108.0 0.1 1.7e-29 102.7 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX71350.1 - 5.9e-07 28.7 0.5 6.6e-05 22.0 0.0 2.9 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EPX71350.1 - 0.016 14.9 0.0 4.2 7.0 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EPX71350.1 - 0.041 12.9 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.1 EPX71352.1 - 5.4e-46 156.3 0.2 7.2e-46 155.9 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EPX71352.1 - 2.5e-14 52.4 11.5 8.9e-08 31.5 1.4 3.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPX71352.1 - 1.8e-08 34.0 6.0 1e-06 28.3 0.2 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EPX71352.1 - 0.068 13.2 7.7 7.8 6.9 0.5 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat GGDEF PF00990.16 EPX71352.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 GGDEF domain LRR_7 PF13504.1 EPX71352.1 - 1.2 9.6 6.5 39 5.0 1.4 4.2 3 1 1 4 4 4 0 Leucine rich repeat Skp1_POZ PF03931.10 EPX71353.1 - 4.3e-13 49.1 0.0 7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain UPF0300 PF08594.5 EPX71354.1 - 1.3e-60 204.0 0.7 1.9e-60 203.4 0.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) Indigoidine_A PF04227.7 EPX71355.1 - 2.3e-124 414.4 0.0 3e-124 414.0 0.0 1.1 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EPX71355.1 - 3.1e-23 82.3 0.0 2.5e-22 79.3 0.0 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EPX71355.1 - 0.015 14.4 0.0 1.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase RRM_1 PF00076.17 EPX71356.1 - 1.5e-48 162.2 0.3 3.1e-13 49.1 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71356.1 - 9.5e-42 140.8 0.1 2.4e-12 46.6 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX71356.1 - 5e-25 87.1 0.1 3.8e-07 29.8 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 EPX71356.1 - 0.00098 18.4 1.7 0.0025 17.1 1.2 1.7 1 0 0 1 1 1 1 Lsm interaction motif Mak10 PF04112.8 EPX71357.1 - 3.6e-40 136.9 0.1 6.7e-40 136.0 0.1 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase NTase_sub_bind PF08780.6 EPX71357.1 - 0.098 12.4 0.1 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like Abp2 PF09441.5 EPX71358.1 - 1.9e-67 226.5 0.1 3.3e-67 225.7 0.1 1.3 1 0 0 1 1 1 1 ARS binding protein 2 DUF2730 PF10805.3 EPX71358.1 - 0.022 14.5 0.2 0.048 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DivIC PF04977.10 EPX71358.1 - 0.068 12.6 0.4 0.14 11.6 0.3 1.5 1 0 0 1 1 1 0 Septum formation initiator AT_hook PF02178.14 EPX71358.1 - 5.1 7.0 8.5 11 6.1 5.9 1.5 1 0 0 1 1 1 0 AT hook motif CENP-C_C PF11699.3 EPX71359.1 - 8.2e-25 86.6 0.1 3.3e-24 84.6 0.0 2.1 1 1 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 EPX71359.1 - 2.5e-09 37.8 1.5 2.5e-09 37.8 1.0 4.1 1 1 2 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 EPX71359.1 - 0.0021 17.5 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AT_hook PF02178.14 EPX71359.1 - 0.67 9.8 18.6 4.1 7.3 4.0 3.3 2 0 0 2 2 2 0 AT hook motif MRP_L53 PF10780.4 EPX71360.1 - 1.3e-13 50.6 0.1 3e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 39S ribosomal protein L53/MRP-L53 F-box-like PF12937.2 EPX71361.1 - 1.2e-08 34.4 0.5 2.8e-08 33.3 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPX71361.1 - 4.5e-07 29.3 0.4 1.1e-06 28.1 0.3 1.6 1 0 0 1 1 1 1 F-box domain Ribosomal_L19e PF01280.15 EPX71362.1 - 2.2e-61 205.9 10.0 2.2e-61 205.9 6.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e DUF3035 PF11233.3 EPX71362.1 - 1.5 8.8 5.6 0.98 9.4 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) Actin PF00022.14 EPX71363.1 - 8.1e-13 47.5 0.0 4.9e-12 44.9 0.0 1.9 1 1 0 1 1 1 1 Actin DRIM PF07539.7 EPX71364.1 - 8.2e-38 128.9 0.1 1.3e-36 125.1 0.0 3.0 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 EPX71364.1 - 0.033 14.2 3.9 3.3 8.0 0.0 5.9 6 0 0 6 6 6 0 HEAT repeat Zn_clus PF00172.13 EPX71365.1 - 0.00011 22.0 11.3 0.00021 21.1 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 EPX71367.1 - 3.9e-91 302.1 0.0 2.8e-45 153.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPX71367.1 - 1.1e-11 44.2 0.0 0.00017 20.7 0.0 3.2 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EPX71367.1 - 1.1e-11 44.9 0.0 0.00019 21.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPX71367.1 - 1.3e-11 44.7 0.1 4.6e-05 23.4 0.0 3.6 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 EPX71367.1 - 7.9e-11 42.2 1.2 0.00031 20.8 0.1 4.5 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EPX71367.1 - 1.2e-10 41.2 0.1 5.1e-05 23.0 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPX71367.1 - 2.9e-09 37.7 0.0 0.00034 21.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EPX71367.1 - 2.9e-08 33.3 5.0 0.1 11.9 0.0 4.3 2 2 2 4 4 4 2 AAA domain AAA_14 PF13173.1 EPX71367.1 - 4.3e-08 33.1 0.0 0.001 19.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EPX71367.1 - 9.9e-07 28.6 0.0 0.041 13.5 0.0 3.6 2 2 1 3 3 3 1 Archaeal ATPase Zeta_toxin PF06414.7 EPX71367.1 - 2.6e-06 26.6 0.0 0.021 13.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 EPX71367.1 - 3.2e-06 26.7 0.7 0.0043 16.7 0.0 3.4 3 0 0 3 3 2 1 Part of AAA domain TIP49 PF06068.8 EPX71367.1 - 4.5e-06 25.6 0.0 0.036 12.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus DUF815 PF05673.8 EPX71367.1 - 4.5e-06 25.7 0.0 0.0066 15.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_33 PF13671.1 EPX71367.1 - 5.7e-06 26.2 0.0 0.0039 17.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EPX71367.1 - 2.4e-05 24.4 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EPX71367.1 - 5.3e-05 22.7 0.0 0.096 12.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EPX71367.1 - 5.4e-05 22.4 0.3 0.078 12.1 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EPX71367.1 - 8.3e-05 22.6 0.0 0.024 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EPX71367.1 - 0.00017 21.1 0.0 0.35 10.4 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EPX71367.1 - 0.00018 21.8 0.0 0.058 13.6 0.0 2.8 2 0 0 2 2 2 1 ABC transporter Rad17 PF03215.10 EPX71367.1 - 0.00043 19.1 0.0 0.011 14.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 EPX71367.1 - 0.0015 18.8 0.0 0.079 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.13 EPX71367.1 - 0.0034 17.0 0.0 0.019 14.6 0.0 2.2 2 1 0 2 2 2 1 Bacterial dnaA protein NACHT PF05729.7 EPX71367.1 - 0.0037 16.9 1.1 0.13 11.9 0.0 3.5 4 0 0 4 4 4 1 NACHT domain CDC48_N PF02359.13 EPX71367.1 - 0.0046 16.8 0.0 0.018 14.9 0.0 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_11 PF13086.1 EPX71367.1 - 0.0047 16.5 0.0 0.19 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EPX71367.1 - 0.01 15.4 1.3 0.36 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EPX71367.1 - 0.01 15.4 0.1 0.039 13.5 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_23 PF13476.1 EPX71367.1 - 0.01 16.1 0.0 0.049 13.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EPX71367.1 - 0.013 15.5 0.0 6 6.9 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EPX71367.1 - 0.017 14.8 0.6 0.72 9.5 0.0 3.3 2 2 2 4 4 4 0 NTPase Parvo_NS1 PF01057.12 EPX71367.1 - 0.022 13.6 0.1 0.25 10.2 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EPX71367.1 - 0.028 13.8 0.0 7.3 6.0 0.0 3.5 3 1 0 3 3 3 0 Sigma-54 interaction domain cobW PF02492.14 EPX71367.1 - 0.038 13.4 0.2 1.9 7.9 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Beta_protein PF14350.1 EPX71367.1 - 0.04 13.0 0.0 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Beta protein ResIII PF04851.10 EPX71367.1 - 0.055 13.2 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.18 EPX71367.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase UPF0079 PF02367.12 EPX71367.1 - 0.074 12.6 0.1 2.9 7.5 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 EPX71367.1 - 0.14 11.1 0.0 0.58 9.0 0.0 1.9 1 1 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 EPX71367.1 - 0.15 11.6 0.0 4.2 6.9 0.0 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain KaiC PF06745.8 EPX71367.1 - 0.26 10.3 0.9 15 4.6 0.0 2.9 2 1 1 3 3 3 0 KaiC PUF PF00806.14 EPX71369.1 - 3e-16 57.8 0.5 0.00038 19.7 0.0 5.6 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EPX71369.1 - 3.7e-06 26.4 0.0 7.7e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX71369.1 - 5.1e-05 23.0 0.0 0.00022 21.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71369.1 - 0.0054 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CPSase_sm_chain PF00988.17 EPX71370.1 - 7.2e-45 151.6 0.0 1.1e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EPX71370.1 - 1.2e-44 152.1 0.0 1.6e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPX71370.1 - 0.00036 20.0 2.1 0.078 12.4 0.1 2.9 1 1 1 2 2 2 2 Peptidase C26 DJ-1_PfpI PF01965.19 EPX71370.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Glycos_transf_2 PF00535.21 EPX71371.1 - 2.1e-25 89.3 0.0 3.2e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EPX71371.1 - 5.2e-08 32.9 0.0 8.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Abhydrolase_1 PF00561.15 EPX71372.1 - 1.1e-37 129.8 0.0 2e-37 128.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPX71372.1 - 1.4e-12 48.0 0.2 6.7e-12 45.7 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPX71372.1 - 0.001 18.8 0.1 0.74 9.5 0.0 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase family Cep57_CLD_2 PF14197.1 EPX71372.1 - 0.017 15.0 0.1 0.058 13.3 0.1 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Abhydrolase_4 PF08386.5 EPX71372.1 - 0.063 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein DUF822 PF05687.8 EPX71372.1 - 0.064 13.6 0.4 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) IlvN PF07991.7 EPX71373.1 - 5.4e-48 162.4 0.1 8e-48 161.9 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EPX71373.1 - 1.3e-46 158.0 0.0 2.2e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EPX71373.1 - 0.027 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EPX71373.1 - 0.03 14.7 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SpoU_methylase PF00588.14 EPX71374.1 - 6.4e-31 107.1 0.0 9e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EPX71374.1 - 1.7e-15 56.9 0.0 4e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Methyltrn_RNA_4 PF09936.4 EPX71374.1 - 0.00012 21.5 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 SAM-dependent RNA methyltransferase Actin PF00022.14 EPX71375.1 - 2.6e-92 309.2 0.0 3.4e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 Actin RLAN PF14401.1 EPX71375.1 - 0.054 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain MreB_Mbl PF06723.8 EPX71375.1 - 0.19 10.2 0.0 0.36 9.3 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein zf-primase PF09329.6 EPX71377.1 - 2.5e-15 55.8 1.2 5.3e-15 54.7 0.8 1.6 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 EPX71377.1 - 0.02 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain WTF PF03303.8 EPX71378.1 - 0.00094 18.6 3.6 0.0018 17.7 2.5 1.5 1 1 0 1 1 1 1 WTF protein Synaptobrevin PF00957.16 EPX71378.1 - 0.29 10.7 0.0 0.29 10.7 0.0 2.7 4 0 0 4 4 4 0 Synaptobrevin DUF3671 PF12420.3 EPX71378.1 - 0.98 9.4 9.0 6.3 6.8 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function Epimerase PF01370.16 EPX71379.1 - 5.1e-17 62.0 0.0 6.9e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPX71379.1 - 6e-16 58.9 0.0 8e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EPX71379.1 - 3.5e-10 39.2 0.0 4.5e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EPX71379.1 - 2.8e-09 36.5 0.0 4.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EPX71379.1 - 7e-08 31.4 0.0 2.4e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPX71379.1 - 1.1e-05 24.4 0.3 2.3e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EPX71379.1 - 7.9e-05 22.6 0.1 0.0002 21.3 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EPX71379.1 - 0.00029 19.8 0.1 0.0016 17.4 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EPX71379.1 - 0.00054 20.3 0.1 0.0013 19.1 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 EPX71379.1 - 0.00085 19.2 0.2 0.002 18.0 0.1 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EPX71379.1 - 0.00088 19.5 0.1 0.0035 17.6 0.0 2.0 2 1 1 3 3 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EPX71379.1 - 0.0055 16.6 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.10 EPX71379.1 - 0.021 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.21 EPX71379.1 - 0.022 14.3 0.0 0.082 12.4 0.0 2.0 3 0 0 3 3 3 0 Zinc-binding dehydrogenase KR PF08659.5 EPX71379.1 - 0.12 12.0 0.1 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 KR domain DUF1673 PF07895.6 EPX71381.1 - 0.24 10.8 1.9 0.63 9.5 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) DUF3671 PF12420.3 EPX71381.1 - 2.4 8.1 6.4 4.4 7.3 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function COX16 PF14138.1 EPX71382.1 - 1.5e-20 73.0 0.3 1.9e-20 72.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Ribosomal_L11 PF00298.14 EPX71383.1 - 2.1e-27 95.0 0.2 3e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EPX71383.1 - 6.4e-23 79.9 0.5 1.1e-22 79.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain NAPRTase PF04095.11 EPX71384.1 - 7.5e-66 221.8 0.7 9.3e-66 221.5 0.5 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Complex1_LYR_2 PF13233.1 EPX71385.1 - 0.004 17.5 0.2 0.014 15.8 0.2 1.9 1 1 0 1 1 1 1 Complex1_LYR-like Nup96 PF12110.3 EPX71386.1 - 3e-74 249.7 0.4 4.4e-74 249.1 0.3 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EPX71386.1 - 3e-46 156.7 0.0 7.3e-46 155.4 0.0 1.7 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EPX71386.1 - 1.6e-16 60.5 364.2 3.6e-11 43.2 30.8 10.2 3 1 10 13 13 13 8 Nucleoporin FG repeat region TPR_MLP1_2 PF07926.7 EPX71387.1 - 1.7e-05 24.5 9.9 1.7e-05 24.5 6.9 16.7 4 3 15 20 20 20 4 TPR/MLP1/MLP2-like protein GCFC PF07842.7 EPX71388.1 - 2.5e-57 194.3 11.1 4.2e-57 193.5 7.7 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EPX71388.1 - 1.5e-16 59.9 0.9 3.6e-16 58.6 0.6 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EPX71388.1 - 6.5e-09 35.5 1.6 6.5e-09 35.5 1.1 2.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site TIP_N PF12457.3 EPX71388.1 - 0.53 10.3 13.5 0.037 14.1 1.4 2.8 3 0 0 3 3 3 0 Tuftelin interacting protein N terminal UBA PF00627.26 EPX71389.1 - 0.004 16.9 0.2 0.0074 16.0 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF1751 PF08551.5 EPX71389.1 - 0.88 9.9 5.1 0.41 10.9 0.5 2.3 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Sod_Fe_C PF02777.13 EPX71390.1 - 4.2e-34 116.5 2.0 7.2e-34 115.8 1.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EPX71390.1 - 3.6e-28 97.6 1.6 6.5e-28 96.8 1.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain LIM_bind PF01803.11 EPX71391.1 - 0.92 8.5 3.4 0.3 10.1 0.2 1.7 2 0 0 2 2 2 0 LIM-domain binding protein adh_short_C2 PF13561.1 EPX71392.1 - 4.8e-25 88.7 0.1 5.9e-25 88.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPX71392.1 - 1.4e-24 86.8 0.0 2.9e-24 85.8 0.0 1.5 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPX71392.1 - 1.7e-12 47.3 0.2 4.2e-12 46.0 0.1 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EPX71392.1 - 6.1e-11 42.2 0.6 2.6e-10 40.1 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPX71392.1 - 2.2e-09 36.6 0.1 2.9e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EPX71392.1 - 4.5e-07 30.0 0.1 8.1e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EPX71392.1 - 1.7e-06 27.3 0.0 2.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 EPX71392.1 - 0.00088 18.2 0.0 0.0031 16.4 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain 3HCDH_N PF02737.13 EPX71392.1 - 0.0037 16.9 0.1 0.044 13.4 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_trans_4_4 PF13579.1 EPX71392.1 - 0.0049 17.0 0.3 1.9 8.6 0.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Saccharop_dh PF03435.13 EPX71392.1 - 0.0054 15.7 0.1 0.0081 15.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EPX71392.1 - 0.011 16.0 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EPX71392.1 - 0.029 14.3 0.2 0.26 11.2 0.1 2.2 1 1 0 1 1 1 0 TrkA-N domain NmrA PF05368.8 EPX71392.1 - 0.036 13.3 0.1 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 EPX71392.1 - 0.068 11.8 0.1 0.13 10.8 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.10 EPX71392.1 - 0.077 12.8 0.1 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EPX71392.1 - 0.11 11.8 0.1 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ribosomal_L14 PF00238.14 EPX71393.1 - 5e-35 119.9 0.0 5.6e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ssu72 PF04722.8 EPX71394.1 - 1.2e-86 288.9 0.0 1.4e-86 288.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 EPX71394.1 - 0.072 13.4 0.1 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase GIT_SHD PF08518.6 EPX71395.1 - 1.5e-19 69.0 2.9 2.2e-10 39.6 1.2 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT tRNA-synt_2d PF01409.15 EPX71396.1 - 2.3e-89 298.8 0.0 3.3e-89 298.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EPX71396.1 - 4.9e-06 26.2 0.0 1.2e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EPX71396.1 - 6.5e-05 21.8 4.1 0.00022 20.0 0.0 3.4 3 1 2 5 5 5 1 tRNA synthetases class II (D, K and N) HTH_45 PF14947.1 EPX71396.1 - 0.063 13.0 1.4 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DWNN PF08783.6 EPX71396.1 - 0.099 12.5 1.2 2.7 8.0 0.0 2.7 3 0 0 3 3 3 0 DWNN domain Hist_deacetyl PF00850.14 EPX71397.1 - 8.1e-81 271.6 0.1 1e-80 271.3 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Plasmod_MYXSPDY PF07981.6 EPX71397.1 - 0.065 12.9 0.7 0.31 10.7 0.2 2.2 2 0 0 2 2 2 0 Plasmodium repeat_MYXSPDY ING PF12998.2 EPX71398.1 - 8.7e-19 67.7 4.2 1.4e-18 67.0 2.9 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EPX71398.1 - 4.9e-10 38.9 9.6 7.9e-10 38.2 6.7 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EPX71398.1 - 0.0041 16.4 3.2 0.0082 15.4 2.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EPX71398.1 - 0.0041 17.2 0.9 0.0041 17.2 0.6 1.9 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EPX71398.1 - 0.0093 15.9 0.6 0.02 14.8 0.4 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain DUF3950 PF13132.1 EPX71398.1 - 0.38 10.3 1.7 8.3 6.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) zf-RING-like PF08746.6 EPX71398.1 - 0.4 10.7 4.1 1 9.3 2.8 1.7 1 1 0 1 1 1 0 RING-like domain Ribosomal_60s PF00428.14 EPX71398.1 - 0.55 10.6 5.2 1.6 9.1 3.6 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein EIF_2_alpha PF07541.7 EPX71399.1 - 8e-41 138.3 0.0 1.8e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EPX71399.1 - 9.3e-12 44.8 2.5 2.1e-11 43.7 1.7 1.6 1 0 0 1 1 1 1 S1 RNA binding domain SH3_9 PF14604.1 EPX71400.1 - 2.1e-10 39.9 0.1 2.5e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPX71400.1 - 1e-07 31.2 0.0 1.2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPX71400.1 - 7.5e-05 22.1 0.0 8.6e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain RNase_PH PF01138.16 EPX71401.1 - 8.4e-33 113.4 0.0 1.2e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EPX71401.1 - 7.9e-12 44.9 0.7 4.7e-11 42.4 0.3 2.1 1 1 1 2 2 2 2 3' exoribonuclease family, domain 2 ACPS PF01648.15 EPX71402.1 - 1.4e-20 73.2 0.0 1.6e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily CLASP_N PF12348.3 EPX71403.1 - 1.2e-76 257.0 11.2 4.7e-68 228.9 0.4 3.3 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EPX71403.1 - 0.0021 18.0 2.2 56 4.2 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat tRNA-synt_1b PF00579.20 EPX71404.1 - 1.8e-75 253.7 0.1 2.3e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RFX_DNA_binding PF02257.10 EPX71405.1 - 4.6e-31 106.7 0.4 9.1e-31 105.8 0.3 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Fcf2 PF08698.6 EPX71406.1 - 1.9e-32 111.2 0.2 4.4e-32 110.0 0.1 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Sybindin PF04099.7 EPX71407.1 - 2e-21 76.1 0.1 2.5e-21 75.8 0.1 1.1 1 0 0 1 1 1 1 Sybindin-like family DUF4335 PF14233.1 EPX71407.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) DUF4499 PF14934.1 EPX71408.1 - 1.2e-08 34.8 2.7 1.5e-08 34.4 1.9 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4499) SET PF00856.23 EPX71409.1 - 8.5e-11 42.4 4.0 2.9e-10 40.6 1.9 2.3 2 1 1 3 3 3 1 SET domain CobT PF06213.7 EPX71409.1 - 0.098 11.7 11.3 0.16 11.1 7.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Phyto_Pns9_10 PF05878.6 EPX71409.1 - 0.22 10.4 3.3 0.4 9.6 2.3 1.4 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Trypan_PARP PF05887.6 EPX71409.1 - 0.46 10.3 5.7 35 4.1 4.9 2.7 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Sporozoite_P67 PF05642.6 EPX71409.1 - 9 4.0 8.2 13 3.4 5.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TatD_DNase PF01026.16 EPX71410.1 - 2.3e-42 144.9 0.0 4.1e-42 144.1 0.0 1.3 1 1 0 1 1 1 1 TatD related DNase DUF2418 PF10332.4 EPX71411.1 - 0.0039 17.4 0.2 0.0077 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF2929 PF11151.3 EPX71411.1 - 0.13 12.3 0.4 0.13 12.3 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) Vpu PF00558.14 EPX71411.1 - 0.18 11.3 1.0 0.56 9.8 0.1 2.1 2 0 0 2 2 2 0 Vpu protein ANTH PF07651.11 EPX71412.1 - 8.4e-77 257.6 0.0 8.4e-77 257.6 0.0 3.5 4 0 0 4 4 4 2 ANTH domain I_LWEQ PF01608.12 EPX71412.1 - 2.5e-62 209.3 6.7 2.5e-62 209.3 4.7 6.1 6 0 0 6 6 6 1 I/LWEQ domain DNA_pol_B PF00136.16 EPX71413.1 - 8.8e-100 334.6 0.0 1.4e-99 334.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EPX71413.1 - 6e-31 107.4 2.0 6.5e-17 61.3 0.1 2.6 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EPX71413.1 - 5e-10 39.2 8.3 1.3e-09 37.9 5.8 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF438 PF04282.8 EPX71413.1 - 0.093 12.5 0.1 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF438) Epimerase PF01370.16 EPX71415.1 - 1.8e-24 86.5 0.1 5.9e-24 84.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPX71415.1 - 5.9e-18 64.5 0.0 1.2e-17 63.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPX71415.1 - 2.3e-15 56.1 0.0 5.3e-15 55.0 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EPX71415.1 - 4.6e-11 43.0 0.0 1.2e-10 41.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPX71415.1 - 1.7e-07 30.4 0.1 2.5e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPX71415.1 - 1.8e-07 31.1 0.1 4.5e-06 26.6 0.0 2.6 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EPX71415.1 - 1.1e-05 24.8 0.1 2.7e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family KR PF08659.5 EPX71415.1 - 0.0014 18.3 0.1 0.0057 16.3 0.0 1.9 2 1 0 2 2 2 1 KR domain NAD_binding_2 PF03446.10 EPX71415.1 - 0.074 12.8 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Mito_carr PF00153.22 EPX71416.1 - 1.3e-70 233.1 0.9 1.3e-23 82.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Med12 PF09497.5 EPX71417.1 - 8e-22 76.9 0.9 2.9e-21 75.2 0.6 2.1 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Slx4 PF09494.5 EPX71419.1 - 6.9e-13 48.1 0.0 1.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease DUF3614 PF12267.3 EPX71419.1 - 0.08 13.2 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) GST_N PF02798.15 EPX71420.1 - 1.6e-11 44.2 0.0 4.7e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPX71420.1 - 2.1e-10 40.6 0.0 3.6e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPX71420.1 - 2.7e-08 33.6 0.0 7.2e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPX71420.1 - 9.8e-08 31.8 0.0 2.6e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPX71420.1 - 4.8e-05 23.1 1.3 0.0005 19.9 0.9 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPX71420.1 - 0.0075 16.7 0.0 0.014 15.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AMMECR1 PF01871.12 EPX71421.1 - 1.4e-40 138.2 0.0 1.7e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Mis14 PF08641.7 EPX71422.1 - 6e-19 68.4 3.4 9e-19 67.9 0.9 2.2 2 1 1 3 3 3 1 Kinetochore protein Mis14 like DUF2115 PF09888.4 EPX71422.1 - 0.16 12.0 0.6 0.55 10.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Frag1 PF10277.4 EPX71423.1 - 1.9e-34 119.0 10.5 1.9e-34 119.0 7.3 3.0 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family POTRA_2 PF08479.6 EPX71423.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 POTRA domain, ShlB-type RF-1 PF00472.15 EPX71424.1 - 1e-18 67.1 0.6 1.8e-18 66.4 0.4 1.4 1 0 0 1 1 1 1 RF-1 domain ubiquitin PF00240.18 EPX71425.1 - 5.2e-34 115.4 1.8 6.1e-34 115.2 0.5 1.7 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 EPX71425.1 - 8.5e-25 86.3 2.3 1.8e-24 85.3 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EPX71425.1 - 1.2e-19 69.7 0.5 2.3e-19 68.8 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPX71425.1 - 5.4e-06 26.5 0.4 4.7e-05 23.5 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPX71425.1 - 0.00032 20.4 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EPX71425.1 - 0.0014 18.5 0.3 0.0027 17.5 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPX71425.1 - 0.012 15.7 0.4 0.016 15.4 0.3 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2318 PF10080.4 EPX71425.1 - 0.018 14.7 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DZR PF12773.2 EPX71425.1 - 0.023 14.4 0.3 0.04 13.7 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Plexin_cytopl PF08337.7 EPX71425.1 - 0.077 11.2 2.0 1.2 7.3 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2870 PF11069.3 EPX71425.1 - 0.08 12.9 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) OrfB_Zn_ribbon PF07282.6 EPX71425.1 - 0.2 11.3 1.1 0.46 10.1 0.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EPX71425.1 - 0.39 10.0 2.5 0.85 8.9 1.7 1.6 1 1 0 1 1 1 0 zinc-ribbon domain CRAL_TRIO PF00650.15 EPX71426.1 - 4.3e-39 133.5 0.0 7.5e-39 132.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EPX71426.1 - 4.9e-09 36.2 0.2 8e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.5 EPX71427.1 - 1.3e-23 82.5 1.0 1.8e-23 82.0 0.2 1.7 2 0 0 2 2 2 1 DASH complex subunit Dam1 DUF1227 PF06777.6 EPX71427.1 - 0.065 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1227) WD40 PF00400.27 EPX71428.1 - 2.7e-10 39.7 0.7 0.0066 16.2 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EPX71428.1 - 1.1e-05 24.8 0.0 0.06 12.8 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.1 EPX71428.1 - 0.049 13.2 0.3 2.1 8.0 0.0 3.2 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal Pho88 PF10032.4 EPX71429.1 - 7.5e-65 217.7 0.0 8.8e-65 217.5 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) 7tm_1 PF00001.16 EPX71429.1 - 0.096 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF2419 PF10343.4 EPX71430.1 - 3.4e-113 377.6 0.0 4e-113 377.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Tom37_C PF11801.3 EPX71431.1 - 8.1e-06 25.7 1.4 0.0015 18.4 0.1 2.3 1 1 1 2 2 2 2 Tom37 C-terminal domain GST_C_3 PF14497.1 EPX71431.1 - 0.00078 19.8 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NFRKB_winged PF14465.1 EPX71431.1 - 0.031 14.1 1.2 0.043 13.6 0.2 1.8 2 0 0 2 2 2 0 NFRKB Winged Helix-like Rtf2 PF04641.7 EPX71432.1 - 0.002 17.3 1.3 0.002 17.3 0.9 2.1 1 1 1 2 2 2 1 Rtf2 RING-finger DUF4570 PF15134.1 EPX71432.1 - 0.08 12.7 9.0 0.85 9.4 4.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) PA26 PF04636.8 EPX71432.1 - 3.6 6.1 10.0 4.3 5.9 6.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2011 PF09428.5 EPX71432.1 - 6.4 6.6 19.7 2.1 8.2 11.6 1.6 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) Ndc1_Nup PF09531.5 EPX71432.1 - 8.1 4.7 12.1 9.2 4.5 8.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Med13_C PF06333.7 EPX71433.1 - 6.6e-17 61.1 2.5 1.3e-16 60.1 1.7 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Myb_DNA-binding PF00249.26 EPX71435.1 - 0.0037 17.2 0.1 0.0091 16.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPX71435.1 - 0.0079 16.2 0.7 0.027 14.5 0.5 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-Nse PF11789.3 EPX71436.1 - 1.2e-20 72.7 1.1 2.3e-20 71.8 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 EPX71436.1 - 0.0021 17.5 1.2 0.0038 16.6 0.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EPX71436.1 - 0.011 15.4 0.8 0.023 14.3 0.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 EPX71436.1 - 0.2 11.5 1.8 0.35 10.7 1.3 1.4 1 0 0 1 1 1 0 Ring finger domain DASH_Dad1 PF08649.5 EPX71437.1 - 1.8e-23 82.0 1.4 2.2e-23 81.7 1.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DUF310 PF03750.8 EPX71437.1 - 0.075 13.2 0.0 0.087 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF310) Ras PF00071.17 EPX71438.1 - 3.1e-51 172.9 0.0 3.7e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX71438.1 - 1.9e-13 50.9 0.0 5.9e-13 49.3 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPX71438.1 - 1.3e-06 27.8 0.0 2.8e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPX71438.1 - 0.00034 19.8 0.0 0.00039 19.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EPX71438.1 - 0.043 13.0 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DAP3 PF10236.4 EPX71438.1 - 0.059 12.2 0.1 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.22 EPX71438.1 - 0.059 13.6 0.1 0.085 13.1 0.1 1.6 1 1 0 1 1 1 0 ABC transporter DUF1673 PF07895.6 EPX71440.1 - 0.3 10.5 3.4 1.5 8.3 2.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) DUF3671 PF12420.3 EPX71440.1 - 4.6 7.2 6.7 7.6 6.5 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function TPR_1 PF00515.23 EPX71441.1 - 0.031 13.8 0.3 0.099 12.2 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_5 PF14634.1 EPX71441.1 - 0.65 9.7 12.0 0.16 11.7 4.8 2.7 2 0 0 2 2 2 0 zinc-RING finger domain PC4 PF02229.11 EPX71442.1 - 5.7e-21 73.5 0.2 9.3e-21 72.8 0.1 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DUF1212 PF06738.7 EPX71443.1 - 4.8e-39 133.8 3.2 1.2e-34 119.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EPX71443.1 - 6.4e-19 68.1 28.6 1.2e-18 67.3 8.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Septin PF00735.13 EPX71444.1 - 7.7e-86 287.5 0.0 1.6e-85 286.5 0.0 1.5 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EPX71444.1 - 1.4e-05 24.9 0.0 4.4e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EPX71444.1 - 0.00021 20.7 0.6 0.0011 18.4 0.0 2.2 2 0 0 2 2 2 1 Ras family GTP_EFTU PF00009.22 EPX71444.1 - 0.0049 16.3 0.2 0.37 10.1 0.0 3.3 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EPX71444.1 - 0.0066 16.9 0.4 0.031 14.7 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein UPF0079 PF02367.12 EPX71444.1 - 0.043 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EPX71444.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EPX71444.1 - 0.38 10.5 0.1 0.38 10.5 0.0 4.1 3 1 1 4 4 4 0 Dynamin family Sporozoite_P67 PF05642.6 EPX71444.1 - 6.1 4.5 12.9 8.8 4.0 8.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen OTU PF02338.14 EPX71445.1 - 2.7e-11 44.1 0.0 4.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Gly-rich_Ago1 PF12764.2 EPX71445.1 - 0.085 13.5 2.4 0.17 12.5 1.7 1.4 1 0 0 1 1 1 0 Glycine-rich region of argonaut CHCH PF06747.8 EPX71446.1 - 1.8e-06 27.6 1.6 2.5e-06 27.2 1.1 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EPX71446.1 - 0.0071 16.1 0.8 0.0087 15.8 0.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like SHMT PF00464.14 EPX71447.1 - 2.7e-206 684.5 0.0 3.1e-206 684.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EPX71447.1 - 2.8e-05 23.4 0.0 4.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EPX71447.1 - 0.069 11.8 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V MIF4G PF02854.14 EPX71448.1 - 5.2e-31 107.6 2.9 1e-30 106.7 2.0 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EPX71448.1 - 9.3e-24 83.3 0.0 4.1e-23 81.2 0.0 2.2 1 0 0 1 1 1 1 MA3 domain Ribosomal_S2 PF00318.15 EPX71449.1 - 1.7e-52 177.6 0.1 1.9e-51 174.3 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S2 tRNA-synt_2b PF00587.20 EPX71450.1 - 5.4e-46 156.3 0.1 9.7e-46 155.4 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPX71450.1 - 3e-20 71.9 0.2 5.2e-20 71.1 0.2 1.4 1 0 0 1 1 1 1 Anticodon binding domain Peptidase_M20 PF01546.23 EPX71451.1 - 7.3e-25 87.5 0.0 1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPX71451.1 - 3.5e-09 36.3 0.0 6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Glucan_synthase PF02364.10 EPX71452.1 - 0 1439.2 0.0 0 1438.1 0.0 1.5 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EPX71452.1 - 2.4e-37 127.3 0.7 8e-37 125.7 0.5 2.0 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aconitase PF00330.15 EPX71453.1 - 8.6e-170 565.1 0.0 2e-169 564.0 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPX71453.1 - 8e-44 148.9 0.1 1.4e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain CBS PF00571.23 EPX71454.1 - 2.1e-40 136.2 11.8 5e-12 45.4 0.2 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EPX71454.1 - 3e-12 46.0 0.1 7.4e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 PB1 domain FlxA PF14282.1 EPX71455.1 - 5.1e-05 23.1 3.3 7.1e-05 22.7 2.3 1.2 1 0 0 1 1 1 1 FlxA-like protein Med9 PF07544.8 EPX71455.1 - 0.0053 16.4 3.9 0.008 15.8 2.7 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EPX71455.1 - 0.006 16.1 3.3 0.0069 16.0 2.3 1.1 1 0 0 1 1 1 1 IncA protein Vps51 PF08700.6 EPX71455.1 - 0.03 14.1 1.2 0.062 13.1 0.8 1.5 1 0 0 1 1 1 0 Vps51/Vps67 TBCA PF02970.11 EPX71455.1 - 0.078 13.0 1.8 0.1 12.6 1.2 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor A DUF904 PF06005.7 EPX71455.1 - 0.2 11.9 4.7 0.32 11.3 3.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) COX7C PF02935.11 EPX71456.1 - 9.7e-14 50.9 0.6 1e-13 50.8 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc GHMP_kinases_N PF00288.21 EPX71457.1 - 2.1e-10 40.5 1.4 3.9e-10 39.6 0.2 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPX71457.1 - 0.0056 16.8 0.0 0.035 14.2 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal Cyto_heme_lyase PF01265.12 EPX71458.1 - 3.4e-75 252.9 3.5 8e-75 251.7 2.5 1.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase COX2-transmemb PF09125.5 EPX71458.1 - 0.18 11.3 0.3 0.33 10.5 0.2 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Ndc1_Nup PF09531.5 EPX71459.1 - 2e-92 310.5 17.9 2.3e-92 310.3 12.4 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup BCDHK_Adom3 PF10436.4 EPX71459.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase PLA2_B PF01735.13 EPX71460.1 - 8.3e-183 608.0 5.0 1e-182 607.7 3.5 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF3336 PF11815.3 EPX71461.1 - 7.7e-42 142.2 0.3 1.2e-41 141.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EPX71461.1 - 1.1e-18 67.9 0.1 2e-18 67.0 0.1 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase AAA PF00004.24 EPX71462.1 - 2.8e-49 166.6 0.0 6e-41 139.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EPX71462.1 - 1.9e-07 31.1 0.0 1.4e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPX71462.1 - 2.7e-07 30.7 0.0 4.1e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EPX71462.1 - 3.4e-06 26.5 0.0 8.4e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 EPX71462.1 - 1.7e-05 24.9 0.0 0.0033 17.5 0.0 3.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPX71462.1 - 2.9e-05 23.8 0.1 0.00098 18.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPX71462.1 - 0.0005 20.8 2.1 0.0028 18.4 0.0 3.4 2 2 1 3 3 1 1 AAA domain AAA_19 PF13245.1 EPX71462.1 - 0.00072 19.2 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EPX71462.1 - 0.00091 19.3 0.0 0.0042 17.2 0.0 2.2 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 EPX71462.1 - 0.0016 18.3 0.0 0.0069 16.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EPX71462.1 - 0.002 18.1 0.0 0.21 11.6 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 EPX71462.1 - 0.0026 17.1 0.4 0.013 14.9 0.0 2.4 2 1 0 2 2 1 1 AAA domain Bromodomain PF00439.20 EPX71462.1 - 0.0032 17.3 0.0 0.0092 15.8 0.0 1.8 1 0 0 1 1 1 1 Bromodomain AAA_18 PF13238.1 EPX71462.1 - 0.0047 17.2 2.1 0.018 15.3 0.0 3.2 3 0 0 3 3 1 1 AAA domain Sigma54_activat PF00158.21 EPX71462.1 - 0.0052 16.2 0.0 0.39 10.1 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_14 PF13173.1 EPX71462.1 - 0.0061 16.4 0.0 0.027 14.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EPX71462.1 - 0.0089 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPX71462.1 - 0.014 14.4 0.0 0.08 11.9 0.0 2.2 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EPX71462.1 - 0.017 15.1 0.8 0.071 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EPX71462.1 - 0.018 14.7 0.1 0.1 12.2 0.0 2.4 2 1 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 EPX71462.1 - 0.023 15.0 0.1 0.12 12.6 0.0 2.3 2 0 0 2 2 1 0 ABC transporter Mg_chelatase PF01078.16 EPX71462.1 - 0.023 13.8 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EPX71462.1 - 0.023 13.9 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 EPX71462.1 - 0.03 13.2 0.0 0.03 13.2 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 EPX71462.1 - 0.038 12.6 0.0 0.076 11.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus ResIII PF04851.10 EPX71462.1 - 0.046 13.5 0.7 2.2 8.0 0.0 3.1 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EPX71462.1 - 0.065 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PIF1 PF05970.9 EPX71462.1 - 0.095 11.6 0.0 0.24 10.2 0.0 1.7 1 0 0 1 1 1 0 PIF1-like helicase DUF3474 PF11960.3 EPX71462.1 - 0.28 11.2 1.7 6.5 6.7 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Telomere_Sde2 PF13019.1 EPX71463.1 - 1.3e-41 141.9 2.4 1.3e-41 141.9 1.6 1.5 2 0 0 2 2 2 1 Telomere stability and silencing TcdB_N PF12918.2 EPX71463.1 - 2.8 8.0 6.7 48 4.1 0.1 3.4 2 1 1 3 3 3 0 TcdB toxin N-terminal helical domain S10_plectin PF03501.10 EPX71464.1 - 9e-43 144.0 0.1 1.1e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Glycos_transf_2 PF00535.21 EPX71465.1 - 2.2e-33 115.3 0.0 2.9e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EPX71465.1 - 1.8e-11 44.2 0.0 2.9e-11 43.6 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EPX71465.1 - 2.6e-08 33.3 0.0 3.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EPX71465.1 - 2.6e-05 23.5 0.0 3.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 EPX71465.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 PS_Dcarbxylase PF02666.10 EPX71466.1 - 2.3e-55 187.0 0.0 4.7e-55 186.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EPX71466.1 - 3.8e-13 49.0 0.7 1.7e-12 47.0 0.1 2.4 3 0 0 3 3 3 1 C2 domain GCV_T PF01571.16 EPX71467.1 - 3.4e-66 222.6 0.0 4.2e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EPX71467.1 - 9.2e-24 83.3 0.1 1.6e-23 82.5 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 EPX71467.1 - 0.00081 19.2 0.0 0.0038 17.0 0.0 1.9 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family JAB PF01398.16 EPX71468.1 - 1.7e-35 121.2 0.0 2.9e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EPX71468.1 - 9.3e-24 83.7 1.1 1.7e-23 82.9 0.8 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EPX71468.1 - 4e-08 32.7 0.0 6.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF1754 PF08555.5 EPX71469.1 - 1.6e-09 38.2 15.6 1.6e-09 38.2 10.8 1.8 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF2362 PF10154.4 EPX71469.1 - 0.51 8.9 7.2 0.62 8.6 5.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Paramyxo_ncap PF00973.14 EPX71469.1 - 0.94 8.1 6.0 1.1 7.8 4.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Hid1 PF12722.2 EPX71469.1 - 1.4 6.5 7.5 1.6 6.2 5.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3347 PF11827.3 EPX71469.1 - 6.9 6.6 11.2 9.1 6.2 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Maf1 PF09174.5 EPX71470.1 - 4.5e-54 183.0 0.6 5.5e-54 182.7 0.4 1.1 1 0 0 1 1 1 1 Maf1 regulator Gti1_Pac2 PF09729.4 EPX71471.1 - 6.3e-52 175.8 0.0 7.5e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family Myb_DNA-bind_6 PF13921.1 EPX71472.1 - 0.27 11.3 9.1 0.051 13.6 0.6 3.7 3 1 0 3 3 3 0 Myb-like DNA-binding domain Pkinase PF00069.20 EPX71473.1 - 4.7e-74 248.8 0.0 5.6e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71473.1 - 2.5e-30 105.4 0.0 3.8e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX71473.1 - 1e-05 24.6 0.0 6e-05 22.1 0.0 2.0 1 1 2 3 3 3 1 Kinase-like Kdo PF06293.9 EPX71473.1 - 1.7e-05 24.0 0.2 3.9e-05 22.8 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX71473.1 - 0.0018 18.0 0.6 0.031 14.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EPX71473.1 - 0.0055 16.0 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family HEM4 PF02602.10 EPX71474.1 - 3.9e-34 117.9 0.0 4.4e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD ATP-synt_F PF01990.12 EPX71474.1 - 0.041 14.2 0.1 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit Polyoma_coat2 PF00761.15 EPX71474.1 - 0.087 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein Fig1 PF12351.3 EPX71475.1 - 2.5e-19 69.8 10.5 2.5e-19 69.8 7.2 1.6 1 1 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EPX71475.1 - 9.2e-05 22.0 23.0 0.0022 17.5 15.9 2.1 1 1 0 1 1 1 1 SUR7/PalI family DUF998 PF06197.8 EPX71475.1 - 0.0068 15.7 9.1 0.0068 15.7 6.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF998) DUF4383 PF14325.1 EPX71475.1 - 6.2 6.8 11.9 0.82 9.6 1.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4383) Ribul_P_3_epim PF00834.14 EPX71477.1 - 1.7e-75 252.5 0.0 1.9e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 EPX71477.1 - 0.026 14.0 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.19 EPX71477.1 - 0.035 13.4 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.12 EPX71477.1 - 0.084 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 PcrB family Iso_dh PF00180.15 EPX71478.1 - 4.4e-96 321.8 0.0 8.1e-96 320.9 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_S17 PF00366.15 EPX71479.1 - 5.3e-31 106.4 1.4 7.8e-31 105.9 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Rot1 PF10681.4 EPX71480.1 - 3.9e-77 258.3 0.6 4.9e-77 258.0 0.4 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal RRM_1 PF00076.17 EPX71481.1 - 4e-35 119.2 0.1 2.3e-18 65.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71481.1 - 2.1e-21 75.6 0.1 1.4e-10 41.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX71481.1 - 1e-15 57.2 0.1 9.6e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EPX71481.1 - 0.01 15.3 0.7 0.14 11.6 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Fungal_trans PF04082.13 EPX71482.1 - 1.1e-28 99.8 3.5 1.1e-28 99.8 2.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX71482.1 - 4.4e-10 39.2 10.2 8.4e-10 38.3 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.13 EPX71483.1 - 1.3e-114 382.8 0.0 1.5e-114 382.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EPX71483.1 - 7.5e-07 28.6 0.3 1.1e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EPX71483.1 - 2e-05 23.6 0.5 3e-05 23.0 0.4 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 EPX71483.1 - 5e-05 22.4 0.4 0.11 11.5 0.3 2.1 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EPX71483.1 - 0.00018 20.5 0.2 0.00027 19.9 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 EPX71483.1 - 0.006 15.5 0.2 0.045 12.6 0.1 2.0 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EPX71483.1 - 0.009 15.3 0.4 0.18 11.0 0.0 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 EPX71483.1 - 0.1 11.6 0.5 1.7 7.6 0.0 2.2 1 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase DJ-1_PfpI PF01965.19 EPX71484.1 - 1.3e-28 99.2 0.0 2.2e-28 98.5 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EPX71484.1 - 0.00022 20.6 0.0 0.00061 19.2 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Glyco_hydro_31 PF01055.21 EPX71485.1 - 2.7e-161 537.3 5.6 3.6e-161 536.9 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 ABC2_membrane PF01061.19 EPX71486.1 - 1.7e-65 220.0 65.1 1.3e-38 132.2 13.4 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EPX71486.1 - 5.2e-26 91.5 0.0 9.7e-14 51.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EPX71486.1 - 3.2e-22 78.1 0.6 8e-14 51.1 0.0 4.2 4 0 0 4 4 4 2 CDR ABC transporter AAA_25 PF13481.1 EPX71486.1 - 0.18 11.1 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ADH_zinc_N PF00107.21 EPX71487.1 - 2.3e-24 85.3 0.0 5.6e-24 84.1 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPX71487.1 - 4e-07 30.9 0.0 8.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase His_Phos_1 PF00300.17 EPX71488.1 - 2.1e-22 79.9 0.0 2.6e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1877 PF08974.5 EPX71488.1 - 0.016 14.8 0.1 0.026 14.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) M-factor PF03855.8 EPX71489.1 - 6.1e-07 29.3 3.5 7.4e-07 29.0 2.4 1.1 1 0 0 1 1 1 1 M-factor Glyco_hydro_38 PF01074.17 EPX71490.1 - 1.2e-88 296.9 0.0 2.1e-88 296.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EPX71490.1 - 8.3e-70 235.8 0.1 1.2e-69 235.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EPX71490.1 - 1.7e-24 85.8 0.0 3.9e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain GFO_IDH_MocA PF01408.17 EPX71491.1 - 3.5e-20 72.6 0.1 5.8e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EPX71491.1 - 2.3e-06 27.9 0.1 5.5e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EPX71492.1 - 3.5e-25 88.8 0.2 2.1e-24 86.2 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPX71492.1 - 2.7e-18 65.6 0.0 5.7e-18 64.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPX71492.1 - 3.3e-14 52.4 0.0 1.3e-13 50.4 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EPX71492.1 - 6.5e-10 39.3 0.0 1.9e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPX71492.1 - 3.3e-07 29.5 0.1 5.7e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPX71492.1 - 6.8e-07 29.3 0.2 2e-05 24.5 0.0 2.9 3 1 0 3 3 3 1 short chain dehydrogenase NmrA PF05368.8 EPX71492.1 - 0.0003 20.1 0.3 0.00075 18.8 0.1 1.7 1 1 1 2 2 2 1 NmrA-like family KR PF08659.5 EPX71492.1 - 0.0048 16.5 0.2 0.024 14.3 0.1 2.1 2 1 0 2 2 2 1 KR domain ADH_zinc_N PF00107.21 EPX71493.1 - 3.8e-13 49.1 0.1 6.2e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPX71493.1 - 0.0032 17.2 0.1 0.019 14.7 0.2 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ammonium_transp PF00909.16 EPX71494.1 - 1.9e-92 309.8 21.8 6.2e-52 176.4 5.9 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family Cu_amine_oxid PF01179.15 EPX71495.1 - 1.3e-169 564.2 0.1 1.7e-169 563.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EPX71495.1 - 7.7e-25 86.8 0.1 2.6e-24 85.2 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EPX71495.1 - 1.7e-11 44.0 0.0 3.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Aminotran_1_2 PF00155.16 EPX71496.1 - 1.6e-66 224.7 0.1 1.9e-66 224.4 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EPX71496.1 - 1.4e-08 33.4 0.1 2.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EPX71496.1 - 8.8e-06 24.6 0.1 1.3e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPX71496.1 - 6.5e-05 22.2 0.1 0.00014 21.1 0.1 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase AcetylCoA_hyd_C PF13336.1 EPX71497.1 - 1.5e-43 148.1 0.0 2.4e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 EPX71497.1 - 8.1e-28 97.5 0.0 1.4e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain CitF PF04223.7 EPX71497.1 - 0.0001 21.1 0.5 0.0002 20.1 0.2 1.5 2 0 0 2 2 2 1 Citrate lyase, alpha subunit (CitF) Fungal_trans PF04082.13 EPX71498.1 - 5.9e-33 113.8 5.4 5.9e-33 113.8 3.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX71498.1 - 4.7e-10 39.2 12.0 8.4e-10 38.4 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 EPX71499.1 - 4.7e-48 163.7 56.7 5.6e-48 163.5 39.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPX71499.1 - 5.8e-22 77.6 50.9 7.7e-22 77.2 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease Arginase PF00491.16 EPX71500.1 - 5.3e-86 288.3 0.0 6.5e-86 288.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EPX71500.1 - 0.045 13.9 0.1 0.073 13.2 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain HhH-GPD PF00730.20 EPX71501.1 - 1.2e-19 70.5 0.0 2.5e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.1 EPX71501.1 - 0.0051 16.9 1.2 0.084 13.0 0.4 2.8 2 1 1 3 3 3 2 Helix-hairpin-helix domain DUF4317 PF14199.1 EPX71501.1 - 0.11 11.3 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) DUF1749 PF08538.5 EPX71502.1 - 8.6e-103 343.3 0.0 9.5e-103 343.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 EPX71502.1 - 1.8e-06 27.7 0.0 5.6e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPX71502.1 - 0.00018 21.1 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPX71502.1 - 0.00075 19.4 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPX71502.1 - 0.0028 16.9 0.0 0.0098 15.1 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family LCAT PF02450.10 EPX71502.1 - 0.0042 16.1 0.0 0.012 14.6 0.0 1.6 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase GTP_EFTU PF00009.22 EPX71503.1 - 4.8e-61 205.4 0.1 6.9e-61 204.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EPX71503.1 - 1.1e-35 121.7 0.0 2.8e-35 120.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EPX71503.1 - 1.7e-19 69.4 0.0 4.3e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EPX71503.1 - 6.2e-14 51.6 0.0 1.5e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EPX71503.1 - 2.2e-12 46.9 1.6 4.4e-12 45.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPX71503.1 - 5.8e-05 23.0 0.1 0.00012 21.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase C2 PF00168.25 EPX71504.1 - 1.1e-51 172.5 5.2 1.2e-17 63.5 0.1 4.5 4 0 0 4 4 4 4 C2 domain DOCK-C2 PF14429.1 EPX71504.1 - 0.0038 16.8 0.5 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.1 EPX71504.1 - 0.0079 15.7 0.1 3.8 6.9 0.0 2.6 2 0 0 2 2 2 2 CEP76 C2 domain SHS2_Rpb7-N PF03876.12 EPX71505.1 - 5.4e-17 61.6 0.0 8.4e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EPX71505.1 - 5.1e-11 42.5 0.0 8.7e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EPX71505.1 - 0.075 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Hydrolase PF00702.21 EPX71506.1 - 3.7e-23 83.0 0.0 1e-22 81.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPX71506.1 - 4.9e-23 82.2 0.0 1.2e-22 81.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EPX71506.1 - 1.1e-21 76.9 0.1 2.3e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EPX71506.1 - 1.5e-05 24.8 0.0 4.8e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPX71506.1 - 0.0056 16.2 0.1 0.04 13.5 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EPX71506.1 - 0.013 14.8 0.1 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Runt PF00853.14 EPX71506.1 - 0.041 13.3 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Runt domain DPPIV_N PF00930.16 EPX71507.1 - 2.7e-99 332.0 5.5 3.9e-99 331.5 3.8 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EPX71507.1 - 2.5e-48 164.1 3.0 3.2e-48 163.7 1.4 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPX71507.1 - 6.2e-08 32.5 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPX71507.1 - 9e-06 25.7 0.3 7.8e-05 22.6 0.0 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 EPX71507.1 - 0.00092 18.6 0.2 0.0035 16.8 0.1 1.8 1 1 0 1 1 1 1 Putative esterase DUF2920 PF11144.3 EPX71507.1 - 0.0027 16.8 0.0 0.0061 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) PAF-AH_p_II PF03403.8 EPX71507.1 - 0.0072 14.6 0.0 2 6.6 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II DLH PF01738.13 EPX71507.1 - 0.01 15.1 0.0 0.045 13.0 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EPX71507.1 - 0.012 15.0 0.2 0.39 10.1 0.1 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 EPX71507.1 - 0.012 15.3 0.1 2.8 7.5 0.0 2.5 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EPX71507.1 - 0.023 14.1 1.9 0.076 12.4 0.6 2.0 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Methyltransf_23 PF13489.1 EPX71508.1 - 1e-11 44.8 0.0 1.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX71508.1 - 1.4e-06 28.8 0.0 3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX71508.1 - 5.3e-06 26.1 0.0 4e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Rhodanese PF00581.15 EPX71508.1 - 1.7e-05 25.1 0.0 3.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_12 PF08242.7 EPX71508.1 - 3.2e-05 24.3 0.0 0.00018 21.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX71508.1 - 8.7e-05 22.8 0.0 0.00021 21.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPX71508.1 - 9.2e-05 22.4 0.0 0.00057 19.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EPX71508.1 - 0.00015 21.0 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 EPX71508.1 - 0.00072 18.9 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 EPX71508.1 - 0.00085 18.8 0.0 0.0019 17.6 0.0 1.5 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.7 EPX71508.1 - 0.0015 18.9 0.0 0.02 15.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EPX71508.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EPX71508.1 - 0.032 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EPX71509.1 - 2.1e-58 196.3 0.0 3.5e-58 195.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPX71509.1 - 2.1e-19 69.3 0.0 2.3e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPX71509.1 - 0.00021 21.1 0.0 0.0023 17.7 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EPX71509.1 - 0.0041 16.4 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EPX71509.1 - 0.058 13.8 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MPP6 PF10175.4 EPX71510.1 - 9.2e-06 25.9 0.5 9.2e-06 25.9 0.3 2.5 1 1 0 2 2 2 1 M-phase phosphoprotein 6 Utp14 PF04615.8 EPX71510.1 - 0.18 9.9 22.1 0.2 9.8 15.3 1.0 1 0 0 1 1 1 0 Utp14 protein YqzL PF14006.1 EPX71510.1 - 0.41 10.8 2.6 1.4 9.1 1.8 1.9 1 0 0 1 1 1 0 YqzL-like protein TATR PF03430.8 EPX71510.1 - 0.49 8.9 10.1 0.54 8.8 7.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Peptidase_M16 PF00675.15 EPX71511.1 - 4e-37 127.2 0.0 2.1e-36 124.9 0.0 2.3 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EPX71511.1 - 1.1e-31 110.0 0.1 1.7e-20 73.4 0.0 2.7 2 1 0 2 2 2 2 Peptidase M16 inactive domain YchF-GTPase_C PF06071.8 EPX71512.1 - 5.4e-29 99.8 0.3 9.1e-29 99.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EPX71512.1 - 4.2e-12 46.0 0.0 9.1e-12 44.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPX71512.1 - 0.0086 15.3 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EPX71512.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 TGS domain BRCT PF00533.21 EPX71513.1 - 6.3e-08 32.6 0.0 0.00015 21.8 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain CPDase PF07823.6 EPX71514.1 - 5.3e-25 88.0 0.3 1.8e-24 86.2 0.2 1.7 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EPX71514.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Glyco_transf_20 PF00982.16 EPX71515.1 - 5.6e-158 526.3 0.0 7.6e-158 525.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EPX71515.1 - 5.3e-50 169.5 0.0 8e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase ox_reductase_C PF08635.5 EPX71516.1 - 1.5e-71 238.3 0.1 2.2e-71 237.8 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EPX71516.1 - 5.4e-19 68.8 0.0 8.9e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPX71516.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain PS_pyruv_trans PF04230.8 EPX71517.1 - 1.1e-26 94.1 0.1 1.9e-26 93.4 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase Methyltransf_16 PF10294.4 EPX71518.1 - 6.6e-13 48.4 0.0 8.2e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 EPX71518.1 - 0.03 13.2 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family GidB PF02527.10 EPX71518.1 - 0.065 12.3 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G COesterase PF00135.23 EPX71519.1 - 9.7e-07 27.8 0.2 0.0031 16.2 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 EPX71519.1 - 0.00071 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EPX71519.1 - 0.0011 17.8 0.1 0.0018 17.1 0.1 1.3 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 EPX71519.1 - 0.015 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Brr6_like_C_C PF10104.4 EPX71521.1 - 3.8e-29 100.9 4.3 5.2e-29 100.4 3.0 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF3805 PF12712.2 EPX71522.1 - 0.011 15.4 0.1 0.022 14.5 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3805) Ribosomal_L1 PF00687.16 EPX71523.1 - 3.8e-55 186.6 1.1 8.2e-55 185.5 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MutS_V PF00488.16 EPX71524.1 - 3.8e-79 265.4 0.0 5.8e-79 264.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPX71524.1 - 2.8e-41 141.5 0.1 6e-41 140.4 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EPX71524.1 - 3.1e-27 94.8 0.1 7.8e-27 93.5 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EPX71524.1 - 2e-13 50.5 1.6 5.1e-13 49.2 0.3 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EPX71524.1 - 1.3e-09 38.1 0.0 3.6e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV zf-CSL PF05207.8 EPX71525.1 - 2.7e-23 81.2 1.0 4.3e-23 80.5 0.7 1.3 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 EPX71525.1 - 0.051 13.1 0.3 0.085 12.4 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF164 PF02591.10 EPX71525.1 - 0.056 13.2 0.1 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain zinc_ribbon_4 PF13717.1 EPX71525.1 - 0.089 12.4 0.3 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EPX71525.1 - 0.15 12.0 1.4 0.34 10.8 1.0 1.6 1 1 0 1 1 1 0 Zinc ribbon domain Ribosomal_L41 PF05162.8 EPX71526.1 - 1.2e-07 31.3 27.7 1.2e-07 31.2 19.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 LTV PF04180.9 EPX71527.1 - 3.7e-111 372.6 26.3 4.9e-111 372.2 18.2 1.1 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.18 EPX71528.1 - 4.3e-17 62.1 0.3 8.7e-15 54.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EPX71528.1 - 6.5e-08 32.0 0.3 2.3e-05 23.6 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EPX71528.1 - 0.00023 20.3 0.2 0.00053 19.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EPX71528.1 - 0.0004 20.2 3.2 0.077 12.8 0.7 3.1 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.11 EPX71528.1 - 0.0039 16.3 0.1 0.009 15.1 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EPX71528.1 - 0.026 15.0 0.1 0.082 13.4 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Spo12 PF05032.7 EPX71529.1 - 6e-13 48.1 1.1 1.3e-12 47.1 0.8 1.6 1 0 0 1 1 1 1 Spo12 family UBA PF00627.26 EPX71530.1 - 4.3e-09 35.9 0.1 7.6e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EPX71530.1 - 0.0072 15.8 0.0 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 UBA-like domain ABC_membrane PF00664.18 EPX71531.1 - 7.4e-90 301.0 45.2 7.5e-48 163.3 6.4 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPX71531.1 - 4.4e-49 166.2 0.4 3.7e-30 104.9 0.0 2.8 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 EPX71531.1 - 8.6e-11 41.4 2.9 0.0031 16.7 0.2 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EPX71531.1 - 5.8e-06 26.4 0.5 0.034 14.1 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 EPX71531.1 - 1.2e-05 24.7 2.7 0.08 12.4 0.0 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EPX71531.1 - 1.3e-05 25.3 4.0 2 8.3 0.0 4.9 3 2 1 4 4 3 2 AAA domain AAA_25 PF13481.1 EPX71531.1 - 4.3e-05 23.0 0.0 0.21 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EPX71531.1 - 5.8e-05 23.0 1.0 0.13 12.2 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EPX71531.1 - 7.7e-05 21.9 0.6 0.14 11.3 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EPX71531.1 - 0.00022 21.6 0.0 0.27 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EPX71531.1 - 0.0011 19.4 0.0 2 8.9 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 EPX71531.1 - 0.0022 17.4 0.6 0.24 10.8 0.0 2.5 2 1 0 2 2 2 1 AAA-like domain NB-ARC PF00931.17 EPX71531.1 - 0.006 15.4 0.1 2.6 6.8 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain DUF87 PF01935.12 EPX71531.1 - 0.011 15.5 0.3 0.1 12.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_22 PF13401.1 EPX71531.1 - 0.011 15.8 1.0 7 6.8 0.2 3.1 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 EPX71531.1 - 0.014 14.3 0.0 0.12 11.2 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.1 EPX71531.1 - 0.056 14.2 0.4 0.78 10.5 0.3 2.6 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 EPX71531.1 - 0.077 11.7 0.0 3.1 6.4 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EPX71531.1 - 0.091 12.5 0.5 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 EPX71531.1 - 0.16 12.2 0.1 1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EPX71531.1 - 0.24 9.9 3.0 3.1 6.2 0.1 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class STE3 PF02076.10 EPX71532.1 - 3.9e-62 209.9 23.3 4.9e-62 209.5 16.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor 7tm_1 PF00001.16 EPX71532.1 - 0.0053 15.9 6.4 0.0053 15.9 4.4 2.9 2 1 0 3 3 3 1 7 transmembrane receptor (rhodopsin family) DUF247 PF03140.10 EPX71532.1 - 0.12 11.3 0.1 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function DUF3958 PF13125.1 EPX71532.1 - 0.14 12.0 1.6 0.33 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) His_biosynth PF00977.16 EPX71533.1 - 1.1e-36 126.2 0.0 1.4e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 EPX71533.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase DUF4602 PF15375.1 EPX71534.1 - 4.3e-05 23.5 19.5 4.3e-05 23.5 13.5 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4602) RNR_inhib PF08591.5 EPX71535.1 - 2.1e-06 28.5 0.0 3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Erf4 PF10256.4 EPX71536.1 - 2.8e-26 91.6 0.0 4.1e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Init_tRNA_PT PF04179.7 EPX71537.1 - 4.8e-132 441.0 0.0 5.8e-132 440.7 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase TFR_dimer PF04253.10 EPX71538.1 - 2.6e-24 85.1 0.0 7.2e-24 83.7 0.0 1.8 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EPX71538.1 - 5.1e-09 36.1 0.0 9.7e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EPX71538.1 - 3.4e-06 26.6 0.0 7.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 PA domain Seryl_tRNA_N PF02403.17 EPX71538.1 - 0.00017 21.6 0.2 0.0086 16.0 0.0 2.5 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF221 PF02714.10 EPX71539.1 - 3.5e-76 256.1 22.3 3.5e-76 256.1 15.5 2.1 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPX71539.1 - 5.8e-33 113.6 4.4 5.8e-33 113.6 3.1 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EPX71539.1 - 6.1e-14 52.3 0.1 1.4e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Oxysterol_BP PF01237.13 EPX71540.1 - 3e-77 259.4 1.6 6.3e-77 258.4 1.1 1.4 1 1 0 1 1 1 1 Oxysterol-binding protein Ribosomal_S16 PF00886.14 EPX71541.1 - 6.2e-24 83.4 0.1 7.6e-24 83.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 DUF2525 PF10733.4 EPX71541.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) HLH PF00010.21 EPX71542.1 - 3.8e-17 61.7 1.7 7e-17 60.8 1.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UPF0182 PF03699.8 EPX71542.1 - 0.032 12.1 0.5 0.048 11.6 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF972 PF06156.8 EPX71542.1 - 0.7 10.2 3.6 0.69 10.2 1.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) WD40 PF00400.27 EPX71544.1 - 5e-57 187.8 16.9 5.7e-12 45.0 0.4 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EPX71544.1 - 2e-08 32.8 4.8 0.33 9.0 0.0 5.1 2 1 3 5 5 5 5 Nucleoporin Nup120/160 eIF2A PF08662.6 EPX71544.1 - 7e-06 25.8 0.2 0.15 11.7 0.0 3.7 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EPX71544.1 - 7.3e-05 22.0 0.5 0.22 10.6 0.0 3.5 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EPX71544.1 - 7.6e-05 21.6 4.9 0.17 10.5 0.0 3.8 1 1 1 2 2 2 2 Nup133 N terminal like SecY PF00344.15 EPX71545.1 - 2.7e-89 299.5 14.0 3.4e-89 299.1 9.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EPX71545.1 - 9.2e-17 60.2 0.2 9.2e-17 60.2 0.1 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p RseC_MucC PF04246.7 EPX71545.1 - 0.22 11.0 0.1 0.22 11.0 0.1 2.4 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC TGS PF02824.16 EPX71546.1 - 3.5e-22 77.9 0.0 7.3e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EPX71546.1 - 1.8e-20 73.0 0.0 3.2e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPX71546.1 - 1.8e-12 46.7 0.0 3.3e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPX71546.1 - 0.00011 22.0 0.3 0.05 13.4 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EPX71546.1 - 0.005 17.3 0.0 0.019 15.4 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 EPX71546.1 - 0.086 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cut12 PF11500.3 EPX71547.1 - 2.5e-20 72.6 1.0 2.5e-20 72.6 0.7 2.9 3 0 0 3 3 3 1 Spindle pole body formation-associated protein IncA PF04156.9 EPX71547.1 - 0.17 11.4 5.6 0.055 13.0 0.5 2.2 2 0 0 2 2 2 0 IncA protein CYSTM PF12734.2 EPX71548.1 - 1e-11 44.7 15.6 1e-11 44.7 10.8 3.1 1 1 2 3 3 3 1 Cysteine-rich TM module stress tolerance CDT1 PF08839.6 EPX71549.1 - 3.3e-10 40.1 0.2 4.2e-09 36.5 0.2 2.3 1 1 0 1 1 1 1 DNA replication factor CDT1 like UTP15_C PF09384.5 EPX71550.1 - 1.4e-44 151.3 0.1 2.6e-44 150.4 0.0 1.5 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EPX71550.1 - 1.6e-26 91.1 9.2 4.4e-08 32.7 0.0 5.9 6 1 0 6 6 6 4 WD domain, G-beta repeat Spc97_Spc98 PF04130.8 EPX71551.1 - 2.6e-101 339.5 19.9 4.8e-101 338.7 13.8 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family AAA PF00004.24 EPX71552.1 - 5.6e-08 33.0 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPX71552.1 - 4.7e-07 30.0 0.1 8.1e-06 26.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EPX71552.1 - 4.2e-06 26.6 0.1 1.2e-05 25.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EPX71552.1 - 4.9e-06 26.2 0.3 1e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EPX71552.1 - 8.6e-05 23.3 1.9 0.00014 22.6 0.1 2.3 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EPX71552.1 - 0.00011 22.2 0.1 0.00099 19.1 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EPX71552.1 - 0.00015 21.5 0.0 0.00044 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EPX71552.1 - 0.00017 20.4 0.5 0.21 10.1 0.0 3.1 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 EPX71552.1 - 0.00042 19.9 0.4 0.00094 18.8 0.3 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPX71552.1 - 0.001 19.3 0.0 0.0048 17.2 0.0 2.1 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 EPX71552.1 - 0.0014 18.4 0.0 0.0041 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EPX71552.1 - 0.0022 17.6 0.1 0.0056 16.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF258 PF03193.11 EPX71552.1 - 0.0037 16.4 0.1 0.0081 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 RuvB_N PF05496.7 EPX71552.1 - 0.0079 15.2 0.0 0.095 11.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EPX71552.1 - 0.013 14.6 0.1 0.03 13.4 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EPX71552.1 - 0.018 15.3 0.1 0.018 15.3 0.0 2.3 2 1 0 2 2 1 0 AAA domain DNA_pol3_delta PF06144.8 EPX71552.1 - 0.022 14.2 0.0 0.058 12.9 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RNA_helicase PF00910.17 EPX71552.1 - 0.025 14.7 0.0 0.075 13.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EPX71552.1 - 0.029 13.2 0.5 0.059 12.2 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.1 EPX71552.1 - 0.052 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 EPX71552.1 - 0.07 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 EPX71552.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EPX71552.1 - 0.096 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 KaiC cobW PF02492.14 EPX71552.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EPX71552.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 NTPase MobB PF03205.9 EPX71552.1 - 0.15 11.7 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Spo7 PF03907.8 EPX71553.1 - 2e-47 161.5 13.3 3.5e-38 131.3 6.4 2.1 1 1 1 2 2 2 2 Spo7-like protein Cucumo_2B PF03263.8 EPX71553.1 - 0.17 12.1 2.0 0.43 10.8 1.4 1.6 1 0 0 1 1 1 0 Cucumovirus protein 2B RRM_6 PF14259.1 EPX71554.1 - 1.1e-11 44.5 0.0 4.3e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX71554.1 - 5.2e-06 26.2 0.0 2.4e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX71554.1 - 5.6e-06 25.8 0.2 4e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EPX71554.1 - 0.0013 18.7 0.4 0.0033 17.4 0.0 1.9 2 0 0 2 2 2 1 PWI domain Iso_dh PF00180.15 EPX71555.1 - 3e-97 325.7 0.1 3.4e-97 325.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 EPX71555.1 - 0.11 12.3 0.0 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Dpy-30 PF05186.8 EPX71556.1 - 1.5e-17 62.7 0.0 2.2e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif DSPc PF00782.15 EPX71558.1 - 1.2e-33 115.4 0.1 1.7e-33 114.9 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPX71558.1 - 0.0095 15.2 0.2 0.018 14.3 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EPX71558.1 - 0.078 11.8 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 EPX71558.1 - 0.094 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Ribosomal_L7Ae PF01248.21 EPX71559.1 - 6.1e-28 96.1 0.8 7.9e-28 95.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Peptidase_S24 PF00717.18 EPX71560.1 - 1.1e-07 31.3 0.0 1.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like ATP_synt_H PF05493.8 EPX71561.1 - 4.9e-21 74.5 4.0 5.1e-21 74.5 2.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit H UPF0104 PF03706.8 EPX71561.1 - 0.026 13.8 0.7 0.029 13.6 0.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) MFS_Mycoplasma PF07672.8 EPX71561.1 - 0.031 13.4 0.4 0.034 13.3 0.3 1.0 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF898 PF05987.8 EPX71561.1 - 0.076 11.8 1.1 0.093 11.5 0.8 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF4131 PF13567.1 EPX71561.1 - 0.079 12.3 2.4 0.094 12.1 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MgtE PF01769.11 EPX71561.1 - 0.09 13.0 0.3 0.11 12.8 0.2 1.0 1 0 0 1 1 1 0 Divalent cation transporter DUF4199 PF13858.1 EPX71561.1 - 0.094 12.6 2.7 0.11 12.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) QueT PF06177.6 EPX71561.1 - 0.11 12.4 0.7 0.11 12.4 0.5 1.0 1 0 0 1 1 1 0 QueT transporter DUF2919 PF11143.3 EPX71561.1 - 0.13 12.0 1.7 0.14 11.9 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) Cation_ATPase_C PF00689.16 EPX71561.1 - 0.17 11.3 2.8 0.19 11.2 1.9 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus YibE_F PF07907.6 EPX71561.1 - 0.19 10.8 1.1 0.21 10.7 0.7 1.0 1 0 0 1 1 1 0 YibE/F-like protein Frag1 PF10277.4 EPX71561.1 - 0.2 11.0 4.5 0.22 10.9 3.1 1.0 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF2207 PF09972.4 EPX71561.1 - 0.27 9.7 1.1 0.26 9.8 0.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) 7tm_3 PF00003.17 EPX71561.1 - 0.47 9.7 5.7 0.56 9.4 4.0 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Caudo_TAP PF02413.12 EPX71562.1 - 0.007 16.5 1.4 0.014 15.5 0.9 1.5 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein Pox_F11 PF04943.7 EPX71562.1 - 0.021 13.6 8.2 0.0097 14.7 3.5 1.8 2 0 0 2 2 2 0 Poxvirus F11 protein DUF848 PF05852.6 EPX71562.1 - 0.041 13.7 9.8 0.073 12.9 6.2 2.0 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) COG5 PF10392.4 EPX71562.1 - 0.046 13.6 7.9 0.13 12.2 5.2 2.0 1 1 0 1 1 1 0 Golgi transport complex subunit 5 V_ATPase_I PF01496.14 EPX71562.1 - 0.057 11.2 12.5 0.033 12.0 7.3 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EPX71562.1 - 0.15 11.0 13.8 0.26 10.1 9.4 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ZapA PF05164.8 EPX71562.1 - 0.2 11.6 5.6 0.13 12.2 1.8 2.3 1 1 1 2 2 2 0 Cell division protein ZapA OEP PF02321.13 EPX71562.1 - 0.21 11.1 4.9 1.1 8.8 2.0 2.3 2 0 0 2 2 2 0 Outer membrane efflux protein ATG16 PF08614.6 EPX71562.1 - 0.28 10.9 17.2 0.076 12.8 8.2 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 EPX71562.1 - 0.44 10.2 17.8 0.33 10.6 10.5 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Selenoprotein_S PF06936.6 EPX71562.1 - 1.1 8.7 5.5 0.75 9.2 2.5 1.7 1 1 1 2 2 2 0 Selenoprotein S (SelS) FlxA PF14282.1 EPX71562.1 - 4.8 7.1 14.6 0.11 12.4 1.5 2.7 1 1 1 2 2 2 0 FlxA-like protein XhlA PF10779.4 EPX71562.1 - 7.6 6.5 9.2 26 4.8 3.4 2.9 2 0 0 2 2 2 0 Haemolysin XhlA Allexi_40kDa PF05549.6 EPX71562.1 - 7.9 5.6 11.4 2.9 7.1 3.2 2.6 2 1 0 3 3 3 0 Allexivirus 40kDa protein Snapin_Pallidin PF14712.1 EPX71562.1 - 8.3 6.8 16.0 31 4.9 5.7 3.4 1 1 1 3 3 3 0 Snapin/Pallidin PDZ_1 PF12812.2 EPX71563.1 - 3.9e-32 109.9 0.0 2.8e-26 91.1 0.0 3.3 3 0 0 3 3 3 2 PDZ-like domain PDZ PF00595.19 EPX71563.1 - 5.3e-10 39.3 0.0 0.015 15.4 0.0 3.5 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Trypsin_2 PF13365.1 EPX71563.1 - 2.2e-09 37.3 0.0 8.2e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EPX71563.1 - 2e-07 30.7 0.0 0.14 12.1 0.0 3.7 3 0 0 3 3 3 3 PDZ domain Peptidase_S3 PF00944.14 EPX71563.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Alphavirus core protein Peptidase_S46 PF10459.4 EPX71563.1 - 0.53 8.6 2.1 0.98 7.7 0.2 1.9 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S7 PF00949.16 EPX71563.1 - 1 8.7 3.1 2.3 7.6 2.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease PAP_assoc PF03828.14 EPX71564.1 - 1.1e-17 63.7 0.0 2.5e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPX71564.1 - 0.00046 20.4 0.0 0.00085 19.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Aa_trans PF01490.13 EPX71565.1 - 1.9e-79 267.0 36.6 2.2e-79 266.8 25.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PHD PF00628.24 EPX71566.1 - 6.9e-09 35.2 7.5 1.2e-08 34.4 5.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EPX71566.1 - 0.012 14.8 6.6 0.023 13.9 4.6 1.4 1 0 0 1 1 1 0 PHD-finger Ribosomal_S14 PF00253.16 EPX71567.1 - 1.1e-17 63.1 1.6 1.2e-17 63.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Terpene_synth PF01397.16 EPX71567.1 - 0.029 13.7 0.0 0.029 13.7 0.0 1.0 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Ribosomal_S27e PF01667.12 EPX71568.1 - 5e-29 99.6 5.2 6.7e-29 99.2 3.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EPX71568.1 - 0.0086 15.9 1.3 0.01 15.7 0.9 1.2 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 EPX71568.1 - 0.082 12.2 2.5 0.12 11.7 1.7 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding HCV_NS4a PF01006.15 EPX71569.1 - 0.056 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a AAA_17 PF13207.1 EPX71569.1 - 0.089 13.6 0.0 0.78 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain MARVEL PF01284.18 EPX71570.1 - 3.8e-20 72.1 14.6 4.8e-20 71.8 10.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain VID27 PF08553.5 EPX71571.1 - 1.3e-274 913.3 14.4 1.5e-274 913.1 10.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Kinesin PF00225.18 EPX71572.1 - 6e-111 370.3 0.0 8.8e-111 369.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain HXXSHH PF07586.6 EPX71572.1 - 0.091 11.6 1.3 11 4.8 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1552) Ribosomal_S19e PF01090.14 EPX71573.1 - 1.5e-59 199.4 0.1 1.7e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Response_reg PF00072.19 EPX71574.1 - 2.6e-23 82.1 0.1 4.3e-16 58.9 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain PseudoU_synth_1 PF01416.15 EPX71575.1 - 3.7e-19 69.0 0.0 9e-09 35.7 0.0 2.7 3 0 0 3 3 3 2 tRNA pseudouridine synthase HAD PF12710.2 EPX71576.1 - 1.1e-19 71.4 0.4 2.5e-19 70.1 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EPX71576.1 - 1.7e-15 56.7 0.0 3.3e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EPX71576.1 - 1.5e-14 54.9 0.7 1.5e-13 51.6 0.5 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPX71576.1 - 2.1e-11 43.6 0.0 5.7e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPX71576.1 - 0.0023 17.5 0.6 0.007 15.9 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YopX PF09643.5 EPX71576.1 - 0.004 17.1 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 YopX protein ketoacyl-synt PF00109.21 EPX71577.1 - 6.9e-55 186.2 0.3 6.3e-54 183.1 0.0 2.1 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EPX71577.1 - 4.5e-33 113.6 0.8 9.9e-33 112.5 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EPX71577.1 - 3.1e-06 26.3 0.1 9.1e-06 24.8 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EPX71577.1 - 0.0059 16.2 2.9 3.3 7.4 0.0 3.3 4 0 0 4 4 4 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PIF1 PF05970.9 EPX71578.1 - 2.3e-63 214.3 2.1 2.7e-60 204.2 0.8 2.5 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 EPX71578.1 - 1.9e-18 66.7 0.0 3.8e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPX71578.1 - 1.3e-06 28.5 0.1 4.2e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 EPX71578.1 - 3.4e-06 25.1 0.1 5.6e-05 21.1 0.0 2.2 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 EPX71578.1 - 1.7e-05 24.8 0.2 0.00017 21.6 0.1 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EPX71578.1 - 1.7e-05 24.4 0.1 3.5e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EPX71578.1 - 0.00012 21.7 0.6 0.032 13.8 0.0 2.9 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EPX71578.1 - 0.00026 20.2 0.0 0.00066 18.9 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EPX71578.1 - 0.00027 20.0 0.1 0.012 14.5 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EPX71578.1 - 0.00078 18.4 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 EPX71578.1 - 0.002 17.4 0.5 0.0051 16.0 0.1 1.8 2 1 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.1 EPX71578.1 - 0.0028 17.6 0.0 0.0062 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 EPX71578.1 - 0.0032 17.0 0.5 4 6.8 0.2 3.0 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EPX71578.1 - 0.0038 17.4 0.1 0.011 15.8 0.1 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EPX71578.1 - 0.0042 16.7 0.1 0.0087 15.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TrwB_AAD_bind PF10412.4 EPX71578.1 - 0.0094 14.6 0.1 0.015 13.9 0.1 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 EPX71578.1 - 0.0096 15.6 0.5 0.058 13.0 0.3 2.1 1 1 0 1 1 1 1 Archaeal ATPase Sigma54_activat PF00158.21 EPX71578.1 - 0.018 14.5 0.1 0.039 13.4 0.1 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EPX71578.1 - 0.026 13.9 0.1 8.9 5.6 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.10 EPX71578.1 - 0.032 13.9 0.7 0.14 11.8 0.5 2.1 1 1 0 1 1 1 0 NTPase RNA_helicase PF00910.17 EPX71578.1 - 0.034 14.3 0.1 0.13 12.4 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Helicase_RecD PF05127.9 EPX71578.1 - 0.043 13.4 1.4 0.24 11.0 1.0 2.1 1 1 0 1 1 1 0 Helicase DUF258 PF03193.11 EPX71578.1 - 0.048 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EPX71578.1 - 0.056 13.1 1.2 0.33 10.6 0.3 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 EPX71578.1 - 0.063 12.0 0.1 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_7 PF12775.2 EPX71578.1 - 0.092 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 UvrD-helicase PF00580.16 EPX71578.1 - 0.35 10.1 3.3 1.1 8.5 0.1 2.8 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain FA_hydroxylase PF04116.8 EPX71579.1 - 2.3e-18 66.6 11.7 2.3e-18 66.6 8.1 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Xan_ur_permease PF00860.15 EPX71580.1 - 2.4e-26 92.1 30.1 1.6e-25 89.4 20.0 2.5 2 1 0 2 2 2 1 Permease family SAGA-Tad1 PF12767.2 EPX71581.1 - 1.7e-41 142.5 0.1 2.2e-41 142.2 0.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Uteroglobin PF01099.12 EPX71581.1 - 0.047 13.5 0.4 3.1 7.6 0.1 2.9 3 0 0 3 3 3 0 Uteroglobin family Rft-1 PF04506.8 EPX71582.1 - 1.9e-132 442.4 24.6 2.3e-132 442.1 17.1 1.0 1 0 0 1 1 1 1 Rft protein His_biosynth PF00977.16 EPX71583.1 - 1.7e-44 151.8 0.2 8.7e-44 149.4 0.1 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EPX71583.1 - 6.9e-29 100.6 0.0 1.3e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EPX71583.1 - 5.8e-07 29.3 0.0 5.9e-06 26.0 0.0 2.3 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EPX71583.1 - 6.2e-06 25.8 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.12 EPX71583.1 - 0.12 11.1 0.0 0.25 10.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) FtsJ PF01728.14 EPX71584.1 - 2.2e-55 187.4 0.0 2.5e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EPX71584.1 - 3.9e-05 23.4 0.0 6.2e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX71584.1 - 0.048 14.2 0.1 0.4 11.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EPX71584.1 - 0.079 12.5 0.0 5 6.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Sugarporin_N PF11471.3 EPX71585.1 - 0.024 14.2 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension dCMP_cyt_deam_1 PF00383.17 EPX71586.1 - 6.6e-26 89.9 2.6 9.9e-26 89.3 1.8 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 EPX71586.1 - 1.9e-06 28.6 0.0 3.8e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPX71586.1 - 4.2e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Cys_rich_CWC PF14375.1 EPX71586.1 - 0.016 15.0 9.8 0.03 14.2 6.8 1.5 1 0 0 1 1 1 0 Cysteine-rich CWC XOO_2897-deam PF14440.1 EPX71586.1 - 0.025 14.2 0.3 0.043 13.5 0.2 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase CoaE PF01121.15 EPX71586.1 - 0.048 13.0 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_33 PF13671.1 EPX71586.1 - 0.089 12.6 0.0 0.19 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain tRNA-synt_His PF13393.1 EPX71587.1 - 1.3e-39 136.1 0.0 4.2e-34 118.0 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EPX71587.1 - 3.5e-17 62.5 0.0 6.7e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.15 EPX71587.1 - 9.5e-16 57.2 1.5 2.6e-15 55.8 1.0 1.8 1 0 0 1 1 1 1 WHEP-TRS domain HGTP_anticodon PF03129.15 EPX71587.1 - 7e-13 48.3 0.0 1.6e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EPX71587.1 - 0.0026 16.5 0.1 0.5 9.0 0.1 2.7 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) ORF6C PF10552.4 EPX71587.1 - 0.082 12.6 0.1 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 ORF6C domain NMT_C PF02799.10 EPX71588.1 - 1.4e-74 249.5 0.0 3.8e-74 248.1 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EPX71588.1 - 8.5e-73 243.3 0.1 1.2e-72 242.7 0.1 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_7 PF13508.1 EPX71588.1 - 0.085 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2919 PF11143.3 EPX71589.1 - 0.0098 15.7 0.1 0.015 15.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2919) Nodulin-like PF06813.8 EPX71589.1 - 0.17 11.0 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Nodulin-like FAM70 PF14967.1 EPX71589.1 - 1.9 7.6 4.9 2.7 7.1 3.4 1.2 1 0 0 1 1 1 0 FAM70 protein Cyclin_N PF00134.18 EPX71590.1 - 1e-10 41.2 0.3 2.1e-10 40.2 0.2 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF1074 PF06382.6 EPX71590.1 - 0.0038 17.2 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1074) Cyclin PF08613.6 EPX71590.1 - 0.038 14.4 0.1 0.05 14.0 0.1 1.3 1 0 0 1 1 1 0 Cyclin Toxin_R_bind_C PF07951.7 EPX71590.1 - 0.074 12.7 0.3 0.12 12.0 0.1 1.5 1 1 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding FTHFS PF01268.14 EPX71591.1 - 3.4e-225 748.2 0.0 1.5e-200 666.9 0.0 2.2 1 1 1 2 2 2 2 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EPX71591.1 - 2.6e-68 228.1 1.9 5.1e-68 227.2 1.3 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EPX71591.1 - 6.1e-38 129.4 0.2 2.1e-37 127.7 0.2 1.9 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Glycos_transf_N PF04413.11 EPX71591.1 - 0.054 12.6 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Mit_ribos_Mrp51 PF11709.3 EPX71592.1 - 2.1e-27 96.1 0.6 4.2e-26 91.9 0.3 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein subunit Adaptin_N PF01602.15 EPX71593.1 - 3.6e-124 414.9 8.7 4.3e-124 414.7 6.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EPX71593.1 - 1.7e-11 44.2 0.0 6.7e-06 26.2 0.0 4.4 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.17 EPX71593.1 - 6.5e-10 38.2 0.4 0.18 11.9 0.0 5.0 4 0 0 4 4 4 3 HEAT repeat Cnd1 PF12717.2 EPX71593.1 - 1.3e-09 38.1 4.8 8e-09 35.5 0.0 3.3 1 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.8 EPX71593.1 - 0.005 15.9 0.7 0.015 14.4 0.0 2.1 3 0 0 3 3 3 1 Armadillo-like Arm PF00514.18 EPX71593.1 - 0.043 13.6 1.1 26 4.8 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ribosomal_L13 PF00572.13 EPX71594.1 - 1.9e-26 92.5 0.1 4.6e-26 91.3 0.0 1.7 3 0 0 3 3 3 1 Ribosomal protein L13 Ribonuc_L-PSP PF01042.16 EPX71595.1 - 5.6e-40 135.8 0.0 6.7e-40 135.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sec61_beta PF03911.11 EPX71596.1 - 1e-18 66.7 0.9 1.3e-18 66.4 0.6 1.1 1 0 0 1 1 1 1 Sec61beta family Syja_N PF02383.13 EPX71597.1 - 1.9e-87 293.0 0.1 3.6e-87 292.1 0.1 1.5 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EPX71597.1 - 3.3e-27 96.0 0.2 1.1e-26 94.2 0.1 1.9 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.11 EPX71598.1 - 1.6e-34 119.1 24.1 1.6e-34 119.1 16.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily SCIMP PF15050.1 EPX71598.1 - 0.083 12.7 0.0 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 SCIMP protein DUF727 PF05303.7 EPX71599.1 - 0.0065 16.2 0.1 0.012 15.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF727) IGR PF09597.5 EPX71600.1 - 2e-18 66.0 2.0 3e-18 65.4 1.4 1.3 1 0 0 1 1 1 1 IGR protein motif APG5 PF04106.7 EPX71601.1 - 1.1e-48 165.3 0.0 1.4e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 TPR_14 PF13428.1 EPX71602.1 - 6e-09 35.7 1.6 0.00029 21.2 0.3 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPX71602.1 - 0.0003 21.3 1.8 0.0051 17.4 0.7 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EPX71602.1 - 0.00068 18.6 2.3 0.14 10.9 0.0 4.1 3 1 1 4 4 4 1 NRDE-2, necessary for RNA interference Suf PF05843.9 EPX71602.1 - 0.0014 18.4 1.0 0.035 13.8 0.1 2.5 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EPX71602.1 - 0.0048 17.2 0.0 0.083 13.2 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Sugar_tr PF00083.19 EPX71603.1 - 4.1e-119 398.1 25.0 4.7e-119 397.9 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPX71603.1 - 1.9e-18 66.3 32.1 2.5e-14 52.7 7.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2763 PF10961.3 EPX71603.1 - 0.014 15.7 0.0 0.014 15.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) MFS_3 PF05977.8 EPX71603.1 - 0.05 11.7 5.8 0.096 10.7 4.0 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector Pox_A14 PF05767.7 EPX71603.1 - 1.5 8.8 6.4 0.19 11.7 0.1 2.6 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 RRM_1 PF00076.17 EPX71604.1 - 3.6e-23 80.9 0.0 1.6e-10 40.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71604.1 - 5e-18 64.8 0.0 1.9e-08 34.1 0.0 2.8 2 1 1 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX71604.1 - 1.2e-16 60.2 0.0 5.9e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EPX71604.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 ESCRT-II PF05871.7 EPX71605.1 - 2.1e-41 141.1 5.2 8.5e-41 139.1 2.9 1.9 1 1 1 2 2 2 1 ESCRT-II complex subunit LSM PF01423.17 EPX71606.1 - 1.7e-19 69.0 0.4 2e-19 68.9 0.3 1.0 1 0 0 1 1 1 1 LSM domain eIF2A PF08662.6 EPX71607.1 - 3.9e-79 264.8 0.1 2e-78 262.6 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EPX71607.1 - 0.006 16.4 0.1 2.6 8.0 0.0 4.1 4 1 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.1 EPX71607.1 - 0.023 14.7 2.4 0.043 13.8 0.4 2.4 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 Bromodomain PF00439.20 EPX71608.1 - 3.3e-28 97.4 1.0 1.7e-20 72.7 0.2 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EPX71608.1 - 3.8e-21 75.0 0.1 1e-20 73.6 0.0 1.8 2 0 0 2 2 2 1 BAH domain NCA2 PF08637.5 EPX71609.1 - 9.2e-87 290.6 9.8 1.5e-86 289.9 6.8 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Fumble PF03630.9 EPX71610.1 - 1e-138 461.8 0.8 1.2e-138 461.6 0.5 1.0 1 0 0 1 1 1 1 Fumble YtxC PF08812.6 EPX71610.1 - 0.097 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 YtxC-like family PTR2 PF00854.16 EPX71611.1 - 8.5e-61 205.7 15.7 8.5e-61 205.7 10.9 1.8 2 1 0 2 2 2 1 POT family CTP_transf_1 PF01148.15 EPX71612.1 - 1.7e-85 286.8 26.9 2.1e-85 286.5 18.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family RRM_1 PF00076.17 EPX71614.1 - 2.8e-16 58.8 0.0 4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71614.1 - 5.9e-10 38.9 0.0 9.1e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX71614.1 - 6.7e-10 38.6 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_2 PF07992.9 EPX71615.1 - 3.2e-06 27.1 0.0 7.6e-05 22.6 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPX71615.1 - 0.0038 17.0 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EPX71615.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HALZ PF02183.13 EPX71616.1 - 0.099 12.3 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper CBFD_NFYB_HMF PF00808.18 EPX71617.1 - 1.7e-16 59.9 0.3 2.7e-16 59.3 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPX71617.1 - 8.4e-11 41.8 0.2 1.3e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EPX71617.1 - 0.063 13.0 0.1 0.095 12.5 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Saccharop_dh PF03435.13 EPX71618.1 - 3.3e-127 424.6 0.0 3.8e-127 424.4 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EPX71618.1 - 2.5e-05 24.4 0.1 4.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EPX71618.1 - 0.0043 17.0 0.1 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding OCD_Mu_crystall PF02423.10 EPX71618.1 - 0.016 13.9 0.2 0.026 13.3 0.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DUF2100 PF09873.4 EPX71618.1 - 0.037 13.4 0.1 0.068 12.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) adh_short PF00106.20 EPX71618.1 - 0.082 12.8 0.2 0.64 9.9 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase SPX PF03105.14 EPX71620.1 - 3.1e-43 148.5 2.2 8.5e-43 147.1 1.6 1.7 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EPX71620.1 - 8.3e-28 97.4 37.4 1.1e-27 97.1 25.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EPX71620.1 - 3.5e-15 55.4 18.3 3.5e-15 55.4 12.7 2.8 1 1 2 3 3 3 2 Citrate transporter CENP-B_dimeris PF09026.5 EPX71620.1 - 0.0053 16.9 3.5 0.013 15.7 2.4 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EPX71620.1 - 0.069 12.6 4.0 0.11 11.9 2.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 EPX71620.1 - 0.34 11.2 3.3 0.82 10.0 2.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2530 PF10745.4 EPX71620.1 - 0.6 10.1 4.2 14 5.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Diphthamide_syn PF01866.12 EPX71621.1 - 1.1e-113 379.5 0.0 1.3e-113 379.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Ribonuc_L-PSP PF01042.16 EPX71621.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 Endoribonuclease L-PSP Ytp1 PF10355.4 EPX71622.1 - 2.6e-104 348.2 8.9 2.6e-104 348.2 6.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EPX71622.1 - 5.8e-25 86.8 11.3 5.8e-25 86.8 7.8 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) FeoB_C PF07664.7 EPX71622.1 - 0.39 10.1 3.7 0.36 10.2 0.2 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus DUF962 PF06127.6 EPX71622.1 - 4.4 7.2 8.6 23 4.9 4.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF962) FA_desaturase PF00487.19 EPX71623.1 - 5.6e-23 81.7 17.4 9.7e-23 80.9 12.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EPX71623.1 - 3.5e-20 70.9 0.1 5.5e-20 70.3 0.1 1.3 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Auto_anti-p27 PF06677.7 EPX71624.1 - 2.8e-16 58.9 1.3 4.2e-16 58.4 0.9 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Sas10 PF09368.5 EPX71625.1 - 1.7e-27 95.3 3.8 1.7e-27 95.3 2.7 2.3 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EPX71625.1 - 6.5e-12 45.4 0.2 2.6e-11 43.5 0.0 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family NIF PF03031.13 EPX71626.1 - 1.1e-48 164.8 0.2 1.8e-48 164.2 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Rrn6 PF10214.4 EPX71627.1 - 5.8e-64 216.5 22.2 2.2e-63 214.6 15.4 1.9 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Tht1 PF04163.7 EPX71627.1 - 0.034 12.5 6.3 0.05 12.0 4.4 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein ResIII PF04851.10 EPX71628.1 - 3e-24 85.8 0.0 7e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPX71628.1 - 2.6e-14 53.0 0.0 2.5e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX71628.1 - 5.7e-14 51.7 0.0 1.7e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPX71628.1 - 0.00017 21.7 0.0 0.00061 19.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EPX71628.1 - 0.0088 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain cobW PF02492.14 EPX71628.1 - 0.013 14.9 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Helicase_C_2 PF13307.1 EPX71628.1 - 0.017 15.0 0.0 0.06 13.3 0.0 1.9 1 1 0 1 1 1 0 Helicase C-terminal domain AAA_14 PF13173.1 EPX71628.1 - 0.048 13.5 0.0 0.3 11.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain TruB_N PF01509.13 EPX71629.1 - 1.4e-41 142.1 0.0 4.9e-40 137.1 0.0 2.3 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Peptidase_M36 PF02128.10 EPX71629.1 - 0.049 12.4 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) Mago_nashi PF02792.9 EPX71629.1 - 0.061 13.0 2.1 2.5 7.7 0.4 2.3 2 0 0 2 2 2 0 Mago nashi protein TraH PF06122.6 EPX71629.1 - 0.22 10.2 1.0 0.37 9.5 0.4 1.5 2 0 0 2 2 2 0 Conjugative relaxosome accessory transposon protein Ribosomal_L18p PF00861.17 EPX71630.1 - 1.6e-43 147.6 0.1 8.4e-43 145.3 0.0 2.1 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EPX71630.1 - 2.9e-30 104.6 3.3 2.9e-30 104.6 2.3 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EPX71630.1 - 0.07 13.1 0.2 0.31 11.1 0.1 2.1 1 1 0 1 1 1 0 Threonine synthase N terminus DUF4598 PF15370.1 EPX71631.1 - 1e-09 38.6 11.0 3.5e-09 36.9 7.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) NAD_kinase PF01513.16 EPX71632.1 - 2.3e-69 233.3 0.0 2.9e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Ribosomal_L32e PF01655.13 EPX71633.1 - 1.2e-48 163.7 1.3 1.5e-48 163.3 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Fmp27_WPPW PF10359.4 EPX71634.1 - 3.6e-124 414.7 7.7 7.7e-124 413.6 5.4 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 EPX71634.1 - 2.8e-121 405.5 8.6 5.5e-121 404.6 1.6 2.6 2 0 0 2 2 2 2 Golgi-body localisation protein domain Fmp27 PF10344.4 EPX71634.1 - 1.4e-66 224.8 31.2 2.2e-61 207.6 10.9 3.2 3 0 0 3 3 3 2 Mitochondrial protein from FMP27 Fmp27_GFWDK PF10347.4 EPX71634.1 - 5.4e-49 166.0 0.0 1.2e-48 164.9 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EPX71634.1 - 7.4e-38 129.7 0.1 2e-37 128.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EPX71634.1 - 6.5e-25 87.5 0.5 5.4e-24 84.5 0.0 3.0 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain CheZ PF04344.8 EPX71634.1 - 0.00065 19.4 0.3 0.0016 18.1 0.2 1.6 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ WD40 PF00400.27 EPX71635.1 - 2.6e-32 109.5 9.3 6.9e-09 35.2 0.1 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EPX71635.1 - 0.013 15.2 0.6 3 7.6 0.0 4.0 4 2 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Fungal_trans PF04082.13 EPX71636.1 - 9.3e-38 129.5 0.2 2e-37 128.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX71636.1 - 0.0041 16.9 5.4 0.0078 16.0 3.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPX71637.1 - 5.5e-32 110.8 32.2 5.5e-32 110.8 22.3 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX71637.1 - 0.00066 18.3 30.5 0.0019 16.8 21.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter ApbA PF02558.11 EPX71638.1 - 6.7e-33 113.2 0.0 1e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EPX71638.1 - 4.6e-29 100.9 0.1 8.9e-29 100.0 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 EPX71638.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 EPX71638.1 - 0.04 13.9 0.0 0.092 12.7 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain DUF3932 PF13068.1 EPX71638.1 - 0.12 12.4 0.1 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) Na_H_Exchanger PF00999.16 EPX71639.1 - 1.5e-64 217.9 26.1 1.8e-64 217.6 18.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EPX71639.1 - 1.5 8.7 5.0 0.65 9.9 0.4 2.6 2 0 0 2 2 2 0 YrhC-like protein DAO PF01266.19 EPX71640.1 - 6.5e-49 166.7 0.0 8.7e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPX71640.1 - 5e-12 45.3 0.5 1.5e-11 43.8 0.3 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EPX71640.1 - 2.4e-08 33.5 0.6 3.3e-05 23.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 EPX71640.1 - 0.00047 19.1 0.3 0.0061 15.4 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EPX71640.1 - 0.0011 18.1 0.2 0.19 10.8 0.0 2.2 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 EPX71640.1 - 0.0011 17.5 0.1 0.0018 16.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EPX71640.1 - 0.0016 17.5 0.1 0.005 15.9 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EPX71640.1 - 0.0029 17.3 1.1 0.013 15.1 0.7 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EPX71640.1 - 0.0033 17.3 0.3 0.0096 15.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPX71640.1 - 0.043 13.8 0.2 0.14 12.2 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPX71640.1 - 0.064 12.1 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein RICTOR_M PF14666.1 EPX71640.1 - 0.074 12.0 0.0 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Melibiase PF02065.13 EPX71641.1 - 1.8e-41 142.1 0.1 2.7e-38 131.7 0.1 2.1 1 1 0 1 1 1 1 Melibiase GST_N PF02798.15 EPX71642.1 - 7.6e-16 58.0 0.0 1.5e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPX71642.1 - 3.7e-15 55.6 0.0 7.6e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPX71642.1 - 5.8e-14 52.0 0.0 9.8e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPX71642.1 - 6.4e-10 38.8 0.0 1.6e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPX71642.1 - 1.5e-05 24.7 0.0 7.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPX71642.1 - 0.0053 17.1 0.0 0.01 16.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AA_permease PF00324.16 EPX71644.1 - 1.7e-133 445.5 29.3 1.9e-133 445.3 20.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPX71644.1 - 1.6e-33 115.8 35.2 2.2e-33 115.4 24.4 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_C26 PF07722.8 EPX71645.1 - 8.3e-45 152.8 0.0 1.1e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 EPX71645.1 - 1e-13 51.1 0.2 1.6e-13 50.5 0.1 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_5 PF13507.1 EPX71645.1 - 0.005 15.7 0.0 0.89 8.4 0.0 2.2 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain Methyltransf_3 PF01596.12 EPX71646.1 - 3.7e-17 62.0 0.0 5.8e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EPX71646.1 - 2.4e-10 41.1 0.0 4.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX71646.1 - 4.9e-06 27.0 0.0 0.00016 22.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPX71646.1 - 0.045 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Aldo_ket_red PF00248.16 EPX71647.1 - 2.1e-64 217.0 0.0 2.4e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EPX71648.1 - 2.7e-22 78.9 42.4 1.8e-20 72.9 29.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 EPX71648.1 - 3e-05 22.3 1.0 5.4e-05 21.4 0.7 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector TRI12 PF06609.8 EPX71648.1 - 3.4e-05 22.2 27.3 7.4e-05 21.1 18.9 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF872 PF05915.7 EPX71648.1 - 0.0087 15.9 0.1 0.0087 15.9 0.1 2.4 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) FAD_binding_8 PF08022.7 EPX71649.1 - 1.4e-23 82.7 0.0 5.4e-23 80.8 0.0 2.1 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EPX71649.1 - 1.6e-18 67.0 2.5 4e-18 65.8 1.1 2.1 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPX71649.1 - 7.4e-11 42.2 9.1 7.4e-11 42.2 6.3 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EPX71649.1 - 0.022 15.3 0.0 0.15 12.6 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain MFS_1 PF07690.11 EPX71650.1 - 1.1e-48 165.7 33.6 1.1e-48 165.7 23.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX71651.1 - 3.3e-109 365.4 28.7 3.9e-109 365.2 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPX71651.1 - 7.4e-16 57.8 26.4 1.6e-10 40.2 4.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EPX71651.1 - 0.0013 17.5 0.9 0.0023 16.6 0.5 1.6 1 1 0 1 1 1 1 BT1 family ORMDL PF04061.9 EPX71651.1 - 0.013 15.0 0.6 0.037 13.5 0.0 2.0 2 0 0 2 2 2 0 ORMDL family FAD-oxidase_C PF02913.14 EPX71652.1 - 6.7e-51 172.9 0.0 9.2e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EPX71652.1 - 8.9e-32 109.4 0.1 1.4e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 EPX71653.1 - 1.9e-44 151.8 73.2 1.1e-36 126.2 31.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX71653.1 - 3e-06 26.1 25.6 1.8e-05 23.5 5.4 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter DUF2427 PF10348.4 EPX71653.1 - 0.89 9.1 6.5 0.27 10.8 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) HSP20 PF00011.16 EPX71655.1 - 9.8e-21 73.5 1.2 1.2e-20 73.2 0.8 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PIH1 PF08190.7 EPX71655.1 - 0.0062 16.0 0.0 0.0069 15.8 0.0 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 DUF4097 PF13349.1 EPX71655.1 - 0.013 15.1 0.1 0.026 14.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) CS PF04969.11 EPX71655.1 - 0.052 14.0 0.4 0.14 12.7 0.1 1.7 2 0 0 2 2 2 0 CS domain OmpA PF00691.15 EPX71655.1 - 0.099 13.0 0.1 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 OmpA family DUF1700 PF08006.6 EPX71656.1 - 1.5 8.0 13.4 2.8 7.2 9.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) ACR_tran PF00873.14 EPX71656.1 - 6.2 4.0 5.9 9.9 3.4 4.1 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family WTF PF03303.8 EPX71657.1 - 0.17 11.2 3.6 0.32 10.3 2.5 1.6 1 1 0 1 1 1 0 WTF protein FAM176 PF14851.1 EPX71657.1 - 3.4 7.3 5.3 0.66 9.6 0.3 2.1 2 0 0 2 2 2 0 FAM176 family PRRSV_2b PF07069.6 EPX71657.1 - 5 7.4 8.9 5.7 7.3 0.8 2.7 2 1 1 3 3 3 0 Porcine reproductive and respiratory syndrome virus 2b MUG2_C PF08593.5 EPX71658.1 - 3.9e-16 59.0 0.0 2e-15 56.7 0.0 2.3 2 0 0 2 2 2 1 Meiotically up-regulated glycoproteins C-terminal DNA_topoisoIV PF00521.15 EPX71658.1 - 0.65 8.7 7.4 0.6 8.8 4.2 1.5 1 1 1 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A RIB43A PF05914.7 EPX71658.1 - 3.5 6.1 17.8 4.6 5.7 8.5 2.1 2 0 0 2 2 2 0 RIB43A Cyt-b5 PF00173.23 EPX71660.1 - 4.5e-21 74.4 0.1 6.2e-21 73.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MRP-L28 PF09812.4 EPX71660.1 - 0.0076 16.0 0.9 0.014 15.2 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 LysM PF01476.15 EPX71660.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 LysM domain M-factor PF03855.8 EPX71661.1 - 4.3e-05 23.4 5.8 6.2e-05 22.9 4.0 1.3 1 0 0 1 1 1 1 M-factor Hemerythrin PF01814.18 EPX71662.1 - 1.9e-12 47.4 0.0 2.9e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain RRN3 PF05327.6 EPX71662.1 - 0.062 11.4 0.0 0.079 11.0 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HSP20 PF00011.16 EPX71664.1 - 2.8e-21 75.2 0.8 3.4e-21 75.0 0.5 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PIH1 PF08190.7 EPX71664.1 - 0.007 15.8 0.0 0.0077 15.7 0.0 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 CS PF04969.11 EPX71664.1 - 0.043 14.3 0.4 0.1 13.1 0.2 1.8 1 1 1 2 2 2 0 CS domain DUF4097 PF13349.1 EPX71664.1 - 0.049 13.1 0.1 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) OmpA PF00691.15 EPX71664.1 - 0.087 13.2 0.1 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 OmpA family MFS_1 PF07690.11 EPX71665.1 - 1.9e-19 69.5 48.5 1.2e-10 40.7 28.7 3.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Prion_bPrPp PF11587.3 EPX71665.1 - 0.14 11.8 0.7 0.62 9.7 0.5 2.1 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal Pox_T4_C PF04490.7 EPX71666.1 - 0.029 14.1 0.2 0.038 13.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus T4 protein, C terminus ACCA PF03255.9 EPX71666.1 - 0.039 13.5 0.0 0.043 13.3 0.0 1.4 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Stathmin PF00836.14 EPX71667.1 - 0.008 15.8 0.7 0.011 15.3 0.5 1.3 1 0 0 1 1 1 1 Stathmin family MFS_1 PF07690.11 EPX71668.1 - 1.1e-40 139.4 49.2 1.1e-40 139.4 34.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPX71668.1 - 2.5e-20 72.2 19.8 3.2e-20 71.8 13.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPX71668.1 - 1.1e-11 44.0 13.9 1.1e-11 44.0 9.6 3.0 2 2 1 3 3 3 1 Sugar (and other) transporter Rad33 PF08730.5 EPX71669.1 - 0.094 12.1 0.1 1.7 8.0 0.2 2.0 1 1 1 2 2 2 0 Rad33 Asparaginase PF00710.15 EPX71670.1 - 8.6e-67 225.2 3.4 1e-66 224.9 2.3 1.1 1 0 0 1 1 1 1 Asparaginase ADH_zinc_N PF00107.21 EPX71671.1 - 8.6e-23 80.3 0.0 1.3e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPX71671.1 - 1e-06 29.6 0.0 2.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Gly_rich_SFCGS PF14272.1 EPX71671.1 - 0.0082 16.0 0.3 0.99 9.3 0.1 2.4 2 0 0 2 2 2 2 Glycine-rich SFCGS PGM_PMM_II PF02879.11 EPX71671.1 - 0.043 14.1 0.0 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Arginase PF00491.16 EPX71672.1 - 3.3e-86 289.0 0.0 4e-86 288.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EPX71672.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain AA_permease_2 PF13520.1 EPX71673.1 - 1.5e-49 168.6 57.8 1.9e-49 168.3 40.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPX71673.1 - 1.9e-24 85.8 49.1 2.9e-24 85.2 34.0 1.2 1 0 0 1 1 1 1 Amino acid permease AIRS PF00586.19 EPX71673.1 - 0.072 13.3 0.1 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain Fungal_trans PF04082.13 EPX71674.1 - 4.8e-35 120.6 9.3 4.8e-35 120.6 6.5 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX71674.1 - 2.7e-07 30.3 13.0 2.7e-07 30.3 9.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MatE PF01554.13 EPX71675.1 - 5.4e-60 201.6 24.8 4.9e-30 104.2 7.6 2.2 2 0 0 2 2 2 2 MatE MFS_1 PF07690.11 EPX71676.1 - 1.1e-20 73.6 39.3 3.1e-12 45.8 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX71676.1 - 1.5e-19 69.9 33.1 2.8e-15 55.8 8.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Sugar_tr PF00083.19 EPX71677.1 - 2.1e-15 56.2 14.4 2.1e-15 56.2 10.0 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPX71677.1 - 1.3e-08 34.0 38.7 2.9e-07 29.5 26.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-DHHC PF01529.15 EPX71678.1 - 6 6.2 7.0 11 5.4 4.9 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase WTF PF03303.8 EPX71679.1 - 3.6e-05 23.2 0.1 5.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 WTF protein DUF95 PF01944.12 EPX71679.1 - 0.0019 17.8 2.5 0.0019 17.8 1.7 1.6 2 0 0 2 2 2 1 Integral membrane protein DUF95 DUF3671 PF12420.3 EPX71679.1 - 0.13 12.2 5.5 0.34 10.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF4577 PF15145.1 EPX71679.1 - 0.13 12.1 0.7 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) MerE PF05052.7 EPX71679.1 - 0.17 11.8 0.2 0.17 11.8 0.1 1.7 2 0 0 2 2 2 0 MerE protein UPF0104 PF03706.8 EPX71679.1 - 0.28 10.4 14.1 2.3 7.3 10.0 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0104) DUF2207 PF09972.4 EPX71679.1 - 0.3 9.6 9.5 0.16 10.5 1.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Peptidase_A24 PF01478.13 EPX71679.1 - 0.99 9.5 6.7 1.6 8.9 4.7 1.3 1 0 0 1 1 1 0 Type IV leader peptidase family M-factor PF03855.8 EPX71680.1 - 4.3e-05 23.4 5.8 6.2e-05 22.9 4.0 1.3 1 0 0 1 1 1 1 M-factor AA_permease PF00324.16 EPX71681.1 - 3.1e-105 352.2 38.9 3.8e-105 351.9 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPX71681.1 - 4.4e-31 107.8 45.5 6.6e-31 107.2 31.6 1.2 1 0 0 1 1 1 1 Amino acid permease bZIP_2 PF07716.10 EPX71682.1 - 5.7e-13 48.4 13.8 5.7e-13 48.4 9.6 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EPX71682.1 - 1.5e-06 28.0 8.2 2.9e-06 27.1 5.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 EPX71682.1 - 0.0046 16.8 1.3 0.0077 16.1 0.9 1.3 1 0 0 1 1 1 1 Haemolysin XhlA bZIP_Maf PF03131.12 EPX71682.1 - 0.03 14.6 6.3 0.054 13.7 4.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 EPX71682.1 - 0.036 13.6 1.2 0.051 13.1 0.8 1.3 1 0 0 1 1 1 0 IncA protein NuA4 PF09340.5 EPX71682.1 - 0.088 12.4 0.8 0.19 11.3 0.6 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 DUF4543 PF15076.1 EPX71682.1 - 0.11 12.4 0.9 0.2 11.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) TPR_10 PF13374.1 EPX71682.1 - 0.22 11.5 0.9 0.4 10.6 0.7 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TMF_DNA_bd PF12329.3 EPX71682.1 - 0.84 9.4 6.0 0.15 11.8 1.6 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ecl1 PF12855.2 EPX71683.1 - 6.7e-06 25.2 7.7 1.3e-05 24.4 5.3 1.5 1 0 0 1 1 1 1 Life-span regulatory factor zf-C4pol PF14260.1 EPX71683.1 - 0.0031 17.4 3.1 0.0036 17.2 2.2 1.2 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta zf-HIT PF04438.11 EPX71683.1 - 0.029 14.0 3.2 0.029 14.0 2.2 1.5 2 0 0 2 2 2 0 HIT zinc finger DUF2116 PF09889.4 EPX71683.1 - 0.04 13.7 1.7 0.053 13.3 1.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DZR PF12773.2 EPX71683.1 - 0.072 12.9 4.2 0.055 13.2 2.0 1.5 2 0 0 2 2 2 0 Double zinc ribbon PHD PF00628.24 EPX71683.1 - 0.65 9.7 9.9 1.5 8.5 6.9 1.7 1 1 0 1 1 1 0 PHD-finger Tnp_zf-ribbon_2 PF13842.1 EPX71683.1 - 0.97 9.8 6.5 0.16 12.4 1.3 1.9 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon OPT PF03169.10 EPX71684.1 - 1.7e-140 469.4 47.9 1.9e-140 469.2 33.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.11 EPX71685.1 - 1.8e-17 63.0 19.9 2.5e-17 62.6 13.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FMN_red PF03358.10 EPX71686.1 - 3.2e-27 94.8 0.0 4.2e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EPX71686.1 - 5.8e-05 22.6 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold CRCB PF02537.10 EPX71687.1 - 1.6e-38 131.1 20.8 1.9e-25 88.9 2.9 2.7 3 1 0 3 3 3 2 CrcB-like protein GST_C PF00043.20 EPX71689.1 - 1.4e-09 37.8 0.2 2e-09 37.3 0.2 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPX71689.1 - 5.2e-08 33.2 0.0 7.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPX71689.1 - 1.3e-07 31.7 0.0 3.5e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPX71689.1 - 3.7e-07 29.9 0.0 9.1e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPX71689.1 - 5.1e-05 23.4 0.0 9.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Aminotran_1_2 PF00155.16 EPX71690.1 - 2.7e-18 66.0 0.0 3.6e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EPX71690.1 - 0.0012 17.5 0.0 0.0031 16.1 0.0 1.8 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 EPX71690.1 - 0.039 13.0 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase TauD PF02668.11 EPX71691.1 - 1.2e-45 156.1 0.6 1.8e-45 155.6 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sulfatase PF00884.18 EPX71692.1 - 1.1e-74 251.3 0.0 1.3e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EPX71692.1 - 6.3e-05 22.4 0.0 0.026 13.8 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EPX71692.1 - 0.0017 16.8 0.0 0.0025 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) ADH_zinc_N PF00107.21 EPX71693.1 - 2.5e-25 88.5 0.2 3.8e-25 87.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPX71693.1 - 2.1e-15 57.7 0.0 3.7e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPX71693.1 - 9.3e-14 51.1 0.1 4.6e-13 48.8 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EPX71693.1 - 0.0029 17.1 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EPX71693.1 - 0.011 15.9 0.1 0.017 15.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 EPX71693.1 - 0.03 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HSP20 PF00011.16 EPX71694.1 - 4.7e-21 74.5 0.7 5.5e-21 74.3 0.5 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PIH1 PF08190.7 EPX71694.1 - 0.007 15.8 0.0 0.0077 15.7 0.0 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 CS PF04969.11 EPX71694.1 - 0.044 14.3 0.3 0.099 13.2 0.2 1.7 1 1 0 1 1 1 0 CS domain DUF4097 PF13349.1 EPX71694.1 - 0.056 12.9 0.1 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) OmpA PF00691.15 EPX71694.1 - 0.089 13.2 0.1 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 OmpA family MFS_1 PF07690.11 EPX71696.1 - 7e-34 117.0 45.9 7e-34 117.0 31.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4381 PF14316.1 EPX71696.1 - 0.08 13.0 0.4 0.66 10.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Sugar_tr PF00083.19 EPX71696.1 - 0.15 10.6 34.1 0.28 9.6 9.6 3.0 2 2 0 2 2 2 0 Sugar (and other) transporter GPI-anchored PF10342.4 EPX71697.1 - 1.6e-10 41.2 0.1 2e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Zn_clus PF00172.13 EPX71698.1 - 5.8e-08 32.5 10.4 1.5e-07 31.1 7.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPX71698.1 - 6.6e-06 25.1 1.8 1.6e-05 23.9 1.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_31 PF01055.21 EPX71699.1 - 8.9e-159 529.0 5.9 1.3e-158 528.4 4.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 D-ser_dehydrat PF14031.1 EPX71700.1 - 3.3e-19 68.8 0.0 7.9e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EPX71700.1 - 4.9e-12 45.8 0.0 6.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Abhydrolase_3 PF07859.8 EPX71702.1 - 1.2e-18 67.4 0.0 1.4e-18 67.2 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 EPX71703.1 - 9.7e-28 96.8 40.1 1.1e-27 96.6 27.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MUG2_C PF08593.5 EPX71704.1 - 4.3e-16 58.8 0.0 2.3e-15 56.5 0.0 2.3 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal Tweety PF04906.8 EPX71704.1 - 0.25 9.7 0.4 0.4 9.0 0.0 1.4 2 0 0 2 2 2 0 Tweety KxDL PF10241.4 EPX71704.1 - 1.7 8.5 6.9 2.7 7.9 0.4 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein Sugarporin_N PF11471.3 EPX71704.1 - 6 6.5 9.0 0.24 11.0 1.2 2.5 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension DUF2802 PF10975.3 EPX71704.1 - 8.4 6.2 9.4 3.9 7.3 1.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) WTF PF03303.8 EPX71706.1 - 0.0008 18.8 1.9 0.0016 17.9 1.3 1.6 1 1 0 1 1 1 1 WTF protein UPF0104 PF03706.8 EPX71706.1 - 0.038 13.2 9.7 0.42 9.8 7.3 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0104) Ca_hom_mod PF14798.1 EPX71706.1 - 0.042 12.8 0.2 0.063 12.2 0.2 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator MerE PF05052.7 EPX71706.1 - 0.07 13.1 0.5 0.07 13.1 0.4 1.6 2 0 0 2 2 2 0 MerE protein HemY_N PF07219.8 EPX71706.1 - 0.78 9.3 0.0 0.78 9.3 0.0 2.3 2 1 0 2 2 2 0 HemY protein N-terminus DUF2207 PF09972.4 EPX71706.1 - 1.6 7.1 10.6 0.37 9.3 1.7 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF3671 PF12420.3 EPX71706.1 - 2.2 8.3 8.6 0.48 10.4 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function AKAP_110 PF05716.8 EPX71707.1 - 0.0095 13.9 0.0 0.015 13.3 0.0 1.2 1 0 0 1 1 1 1 A-kinase anchor protein 110 kDa (AKAP 110) Oxidored_FMN PF00724.15 EPX71708.1 - 1.6e-110 369.3 0.0 1.8e-110 369.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cyt-b5 PF00173.23 EPX71709.1 - 2.2e-21 75.4 0.1 3e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MRP-L28 PF09812.4 EPX71709.1 - 0.049 13.4 1.6 0.09 12.6 1.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 WTF PF03303.8 EPX71710.1 - 0.0027 17.1 1.7 0.0049 16.3 1.1 1.5 1 1 0 1 1 1 1 WTF protein Ca_hom_mod PF14798.1 EPX71710.1 - 0.14 11.0 2.0 0.2 10.6 1.4 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator DUF3671 PF12420.3 EPX71710.1 - 2.2 8.3 12.2 7.1e+02 0.2 8.4 2.2 1 1 0 1 1 1 0 Protein of unknown function Lactamase_B_2 PF12706.2 EPX71711.1 - 5.4e-24 84.8 0.0 6.7e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPX71711.1 - 4.5e-11 42.7 0.0 5.8e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPX71711.1 - 0.019 14.5 0.1 0.03 13.9 0.0 1.4 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily WTF PF03303.8 EPX71712.1 - 0.00017 21.1 3.1 0.00046 19.6 2.2 1.6 1 1 0 1 1 1 1 WTF protein HemY_N PF07219.8 EPX71712.1 - 0.14 11.7 0.3 0.14 11.7 0.2 1.7 2 0 0 2 2 2 0 HemY protein N-terminus HSP20 PF00011.16 EPX71714.1 - 1.7e-12 47.0 0.2 2.2e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EPX71714.1 - 0.08 13.5 0.1 0.11 13.0 0.1 1.3 1 0 0 1 1 1 0 CS domain DEAD PF00270.24 EPX71715.1 - 4.2e-11 42.6 0.0 8.1e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX71715.1 - 4.3e-08 32.9 0.0 1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX71715.1 - 0.00036 20.4 0.6 0.0074 16.1 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3505 PF12013.3 EPX71715.1 - 0.00072 19.7 0.1 0.0026 17.9 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Hemerythrin PF01814.18 EPX71716.1 - 4.6e-14 52.7 0.5 7.7e-14 51.9 0.1 1.5 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain adh_short PF00106.20 EPX71717.1 - 2e-32 112.4 0.7 2.4e-32 112.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPX71717.1 - 2.5e-27 96.2 0.1 3.1e-27 95.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPX71717.1 - 7.6e-15 55.0 0.3 1.1e-14 54.5 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPX71717.1 - 0.0005 19.5 0.0 0.00085 18.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EPX71717.1 - 0.01 15.5 0.3 0.017 14.7 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPX71717.1 - 0.058 12.5 0.1 0.12 11.5 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EPX71717.1 - 0.13 12.2 1.1 0.25 11.3 0.8 1.4 1 1 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 EPX71718.1 - 6.5e-30 104.2 0.1 7.6e-30 104.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPX71718.1 - 3.6e-20 72.7 0.1 4.7e-20 72.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPX71718.1 - 5.3e-09 35.9 0.0 6.8e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 EPX71718.1 - 0.0012 18.0 0.2 0.0018 17.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 EPX71718.1 - 0.015 13.9 0.0 0.025 13.2 0.0 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase NAD_binding_10 PF13460.1 EPX71718.1 - 0.017 15.1 0.5 0.026 14.5 0.4 1.3 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EPX71718.1 - 0.057 12.8 0.1 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EPX71718.1 - 0.094 12.5 0.3 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_6 PF00970.19 EPX71719.1 - 1.3e-12 47.7 0.0 2.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EPX71719.1 - 2.1e-09 37.8 0.0 5.7e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.17 EPX71719.1 - 2.8e-09 37.2 0.0 1.4e-08 35.0 0.0 2.1 1 1 0 1 1 1 1 Globin NAD_binding_6 PF08030.7 EPX71719.1 - 0.00041 20.2 0.2 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 EPX71719.1 - 0.026 14.1 0.1 0.055 13.1 0.0 1.7 2 1 0 2 2 2 0 Protoglobin Post_transc_reg PF13797.1 EPX71719.1 - 0.059 12.9 0.4 0.13 11.8 0.3 1.5 1 0 0 1 1 1 0 Post-transcriptional regulator LisH PF08513.6 EPX71720.1 - 4.6e-09 35.7 1.0 1.1e-08 34.5 0.7 1.7 1 0 0 1 1 1 1 LisH IATP PF04568.7 EPX71721.1 - 2e-13 50.2 0.1 2.2e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Trep_dent_lipo PF09710.5 EPX71721.1 - 0.046 12.4 0.5 0.051 12.2 0.4 1.1 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) DUF1816 PF08846.5 EPX71721.1 - 0.065 12.9 0.1 0.099 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) PspB PF06667.7 EPX71721.1 - 0.45 10.4 2.2 0.61 10.0 1.5 1.2 1 0 0 1 1 1 0 Phage shock protein B Acetyltransf_1 PF00583.19 EPX71722.1 - 3e-06 27.1 0.0 5.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EPX71722.1 - 3.3e-06 26.9 0.1 2.1e-05 24.3 0.0 2.1 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPX71722.1 - 5.8e-06 26.3 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pro_dh PF01619.13 EPX71723.1 - 5.6e-47 160.2 0.2 1e-46 159.4 0.1 1.3 1 0 0 1 1 1 1 Proline dehydrogenase NT-C2 PF10358.4 EPX71725.1 - 9.4e-25 86.7 0.0 2.4e-24 85.4 0.0 1.6 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2428 PF10350.4 EPX71726.1 - 1.7e-70 236.9 0.0 2.9e-70 236.2 0.0 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) DEAD PF00270.24 EPX71727.1 - 3.8e-40 137.1 0.2 7e-40 136.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX71727.1 - 1.9e-21 75.6 0.0 9.7e-11 41.3 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EPX71727.1 - 0.0023 17.7 5.0 0.0053 16.6 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EPX71727.1 - 0.21 10.8 0.1 0.21 10.8 0.0 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain UCH PF00443.24 EPX71728.1 - 3.5e-88 295.1 0.0 7.1e-88 294.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPX71728.1 - 1.9e-22 80.0 0.0 3.4e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EPX71728.1 - 6.4e-12 45.7 0.2 6.4e-12 45.7 0.1 2.7 2 1 0 2 2 2 1 DUSP domain Zn-ribbon_8 PF09723.5 EPX71728.1 - 0.075 13.0 1.6 2.5 8.1 0.4 2.5 2 0 0 2 2 2 0 Zinc ribbon domain PDH PF02153.12 EPX71729.1 - 8.6e-14 51.0 0.0 1.2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EPX71729.1 - 2.1e-05 24.8 0.0 0.00012 22.3 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EPX71729.1 - 6.3e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EPX71729.1 - 0.00062 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EPX71729.1 - 0.0028 17.3 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EPX71729.1 - 0.0029 17.0 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 EPX71729.1 - 0.036 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain RYDR_ITPR PF01365.16 EPX71730.1 - 0.00088 18.5 0.4 0.0024 17.1 0.3 1.8 1 0 0 1 1 1 1 RIH domain TFIID-18kDa PF02269.11 EPX71731.1 - 1e-26 92.5 0.2 1.2e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EPX71731.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Pkinase PF00069.20 EPX71732.1 - 8.9e-48 162.6 0.0 1.2e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71732.1 - 2.3e-29 102.2 0.0 3.3e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX71732.1 - 0.0013 17.7 0.0 0.0027 16.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPX71732.1 - 0.0018 17.3 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TB PF00683.12 EPX71732.1 - 0.019 14.4 1.8 0.045 13.3 1.2 1.6 1 0 0 1 1 1 0 TB domain RIO1 PF01163.17 EPX71732.1 - 0.055 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family SAC3_GANP PF03399.11 EPX71733.1 - 2.5e-50 170.9 1.2 3.3e-50 170.4 0.8 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPX71733.1 - 8.7e-06 25.5 0.0 2.8e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Thymidylate_kin PF02223.12 EPX71734.1 - 4.5e-51 172.8 0.1 5.2e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase Arch_ATPase PF01637.13 EPX71734.1 - 0.0005 19.8 0.4 0.0037 17.0 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 EPX71734.1 - 0.0015 18.8 0.7 0.034 14.4 0.4 2.6 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EPX71734.1 - 0.0041 17.0 0.5 0.022 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EPX71734.1 - 0.0083 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EPX71734.1 - 0.013 14.7 0.1 0.059 12.5 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EPX71734.1 - 0.013 15.3 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_35 PF14516.1 EPX71734.1 - 0.018 13.7 0.7 0.023 13.3 0.1 1.4 2 0 0 2 2 2 0 AAA-like domain SKI PF01202.17 EPX71734.1 - 0.018 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase NTS_2 PF15448.1 EPX71734.1 - 0.029 14.6 0.0 0.099 12.9 0.0 1.9 2 0 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein AAA_16 PF13191.1 EPX71734.1 - 0.031 14.2 0.0 0.031 14.2 0.0 1.2 1 1 0 1 1 1 0 AAA ATPase domain ADK PF00406.17 EPX71734.1 - 0.044 13.6 0.1 0.16 11.8 0.1 2.1 1 1 0 1 1 1 0 Adenylate kinase AAA_22 PF13401.1 EPX71734.1 - 0.068 13.3 0.1 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain ThiI PF02568.9 EPX71734.1 - 0.07 12.5 0.1 1.4 8.2 0.0 2.0 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) MobB PF03205.9 EPX71734.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EPX71734.1 - 0.096 12.9 0.4 0.18 12.0 0.3 1.7 1 1 0 1 1 1 0 ABC transporter Methyltransf_11 PF08241.7 EPX71735.1 - 7.8e-20 71.1 0.0 1.9e-19 69.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX71735.1 - 1.9e-17 63.2 0.0 2.6e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX71735.1 - 1.8e-15 57.2 0.0 6.5e-15 55.4 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX71735.1 - 7.4e-15 55.0 0.0 1.4e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX71735.1 - 3.9e-12 46.7 0.0 9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX71735.1 - 2.6e-11 43.7 0.0 4.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPX71735.1 - 1.4e-10 40.8 0.0 2.1e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EPX71735.1 - 1e-09 37.8 0.0 1.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EPX71735.1 - 7.6e-09 35.6 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPX71735.1 - 8.7e-09 34.8 0.0 4.6e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EPX71735.1 - 2.3e-08 33.6 0.0 3.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 EPX71735.1 - 1.2e-06 27.8 0.0 4.2e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 EPX71735.1 - 5e-06 26.0 0.0 8.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EPX71735.1 - 7.4e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPX71735.1 - 0.00011 21.4 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.11 EPX71735.1 - 0.00018 19.9 0.0 0.00026 19.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DOT1 PF08123.8 EPX71735.1 - 0.0004 19.7 0.0 0.00063 19.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 EPX71735.1 - 0.0012 18.4 0.0 0.002 17.6 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.6 EPX71735.1 - 0.0013 18.2 0.0 0.0046 16.4 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) DREV PF05219.7 EPX71735.1 - 0.0013 17.6 0.0 0.0063 15.4 0.0 1.9 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_5 PF01795.14 EPX71735.1 - 0.0072 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 MraW methylase family TehB PF03848.9 EPX71735.1 - 0.011 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.13 EPX71735.1 - 0.024 13.8 0.0 0.052 12.7 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase Pox_MCEL PF03291.11 EPX71735.1 - 0.057 12.2 0.0 2.7 6.7 0.0 2.1 1 1 0 1 1 1 0 mRNA capping enzyme TrkA_N PF02254.13 EPX71735.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain N6_N4_Mtase PF01555.13 EPX71735.1 - 0.066 12.6 0.0 0.48 9.8 0.0 2.1 2 1 0 2 2 2 0 DNA methylase Methyltransf_4 PF02390.12 EPX71735.1 - 0.069 12.1 0.0 0.15 11.0 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.14 EPX71735.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF2406 PF10295.4 EPX71736.1 - 5.6e-18 65.2 0.1 6e-17 61.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) DUF2973 PF11189.3 EPX71737.1 - 0.067 12.9 1.1 0.094 12.4 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2973) DUF1049 PF06305.6 EPX71737.1 - 0.084 12.3 0.2 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) SIT PF15330.1 EPX71737.1 - 0.15 12.1 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT F-box-like PF12937.2 EPX71738.1 - 3.9e-06 26.4 1.1 3.9e-06 26.4 0.8 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPX71738.1 - 0.00043 19.8 1.3 0.00095 18.7 0.9 1.6 1 0 0 1 1 1 1 F-box domain BRO1 PF03097.13 EPX71738.1 - 0.027 13.2 0.2 0.027 13.2 0.1 1.4 2 0 0 2 2 2 0 BRO1-like domain DUF1253 PF06862.7 EPX71739.1 - 6.5e-163 542.2 5.6 1.1e-162 541.4 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DUF2681 PF10883.3 EPX71739.1 - 0.15 12.2 1.6 0.45 10.7 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CTP_transf_2 PF01467.21 EPX71740.1 - 9.4e-23 80.9 0.1 5.6e-22 78.4 0.0 2.1 2 0 0 2 2 2 1 Cytidylyltransferase CagX PF03524.10 EPX71740.1 - 1 8.5 6.9 2.7 7.2 4.8 1.7 1 1 0 1 1 1 0 Conjugal transfer protein AMP-binding PF00501.23 EPX71741.1 - 4e-85 285.7 0.0 5.1e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPX71741.1 - 7.3e-15 55.6 0.0 1.9e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EPX71741.1 - 0.0016 17.0 0.0 0.01 14.4 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter adh_short PF00106.20 EPX71742.1 - 1.6e-27 96.5 0.7 1.9e-27 96.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPX71742.1 - 2.2e-21 76.7 0.6 2.8e-21 76.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPX71742.1 - 4e-08 33.1 0.9 6.3e-08 32.4 0.7 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPX71742.1 - 2.3e-07 30.9 0.4 2.9e-07 30.6 0.3 1.1 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EPX71742.1 - 0.00029 20.0 0.0 0.00086 18.5 0.0 1.6 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EPX71742.1 - 0.0034 17.1 0.2 0.0077 16.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EPX71742.1 - 0.092 11.8 1.7 0.47 9.5 0.2 2.3 1 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ank_5 PF13857.1 EPX71743.1 - 1.5e-07 31.4 0.0 3.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPX71743.1 - 1.2e-05 25.5 0.1 2.7e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPX71743.1 - 1.3e-05 24.7 0.0 2.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EPX71743.1 - 0.0051 17.2 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPX71743.1 - 0.008 16.3 0.0 0.026 14.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat DUF971 PF06155.7 EPX71743.1 - 0.014 15.7 0.6 0.049 14.0 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF971) RRM_1 PF00076.17 EPX71744.1 - 1e-16 60.3 0.0 2.5e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71744.1 - 3.5e-13 49.3 0.1 4.6e-12 45.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX71744.1 - 9.8e-10 38.1 0.1 2.1e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dopey_N PF04118.9 EPX71744.1 - 0.019 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Dopey, N-terminal Semialdhyde_dhC PF02774.13 EPX71745.1 - 7.7e-44 149.7 0.1 1.4e-43 148.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EPX71745.1 - 1e-33 116.2 0.0 2.3e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 EPX71745.1 - 1.7e-05 25.3 0.0 0.0007 20.1 0.0 2.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 EPX71745.1 - 0.0017 18.2 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EPX71745.1 - 0.01 14.8 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase EXS PF03124.9 EPX71746.1 - 2.1e-79 267.0 39.1 2.8e-79 266.6 27.1 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EPX71746.1 - 1.7e-35 123.1 13.4 9.5e-35 120.7 9.3 1.9 1 1 0 1 1 1 1 SPX domain Pkinase PF00069.20 EPX71747.1 - 3.2e-32 111.6 0.0 4.9e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71747.1 - 9.3e-24 83.8 0.0 1.3e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX71747.1 - 0.012 14.5 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EPX71747.1 - 0.25 11.0 0.0 0.74 9.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Arrestin_C PF02752.17 EPX71748.1 - 3.1e-07 30.5 0.7 7.3e-07 29.3 0.5 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Pal1 PF08316.6 EPX71749.1 - 7.7e-35 120.3 9.9 1.7e-33 116.0 3.4 3.4 2 1 0 2 2 2 1 Pal1 cell morphology protein DUF1353 PF07087.6 EPX71749.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) MBOAT PF03062.14 EPX71750.1 - 7.8e-28 97.5 34.9 7.8e-28 97.5 24.2 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EPX71750.1 - 0.0024 17.9 3.5 0.0024 17.9 2.4 3.2 5 0 0 5 5 5 1 Membrane bound O-acyl transferase family NUC153 PF08159.7 EPX71751.1 - 8.3e-09 34.8 3.5 1.8e-08 33.8 2.4 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EPX71751.1 - 0.084 12.7 0.3 29 4.7 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Pox_MCEL PF03291.11 EPX71752.1 - 1.2e-98 330.0 0.0 1.7e-98 329.6 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.1 EPX71752.1 - 1.4e-12 47.8 0.0 3.3e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX71752.1 - 1.4e-10 40.9 0.0 2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX71752.1 - 1.4e-10 41.7 0.0 2.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX71752.1 - 4.1e-10 40.0 0.0 7.3e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX71752.1 - 5.3e-10 39.6 0.0 1.1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX71752.1 - 1.7e-09 37.6 0.0 2.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPX71752.1 - 0.00019 21.4 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPX71752.1 - 0.0024 16.9 0.0 0.0045 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EPX71752.1 - 0.034 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 EPX71752.1 - 0.16 10.9 0.0 0.35 9.7 0.0 1.5 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family RCC1 PF00415.13 EPX71753.1 - 1.4e-25 89.2 0.0 3.1e-07 30.4 0.0 4.8 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EPX71753.1 - 4.5e-23 81.3 4.7 2.9e-12 46.5 0.1 3.3 2 1 1 3 3 3 2 BTB/POZ domain Ank_5 PF13857.1 EPX71753.1 - 8.2e-11 41.7 0.0 3.2e-06 27.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPX71753.1 - 3.4e-10 40.1 0.1 7.4e-08 32.6 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPX71753.1 - 2.5e-09 37.3 0.1 9.1e-09 35.5 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPX71753.1 - 3.7e-09 35.9 0.0 0.0041 16.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat RCC1_2 PF13540.1 EPX71753.1 - 5.8e-07 28.9 12.5 4.3e-06 26.1 0.3 4.6 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 EPX71753.1 - 8.1e-07 28.6 0.2 0.022 14.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Sdh_cyt PF01127.17 EPX71754.1 - 4.5e-27 94.2 1.0 5.7e-27 93.9 0.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sin_N PF04801.8 EPX71755.1 - 4.6e-30 104.8 0.2 5.9e-30 104.4 0.1 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region Ribosomal_L24e PF01246.15 EPX71756.1 - 1.5e-30 104.8 0.3 1.5e-30 104.8 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e ATP-synt_E PF05680.7 EPX71756.1 - 9.4 6.2 11.0 66 3.5 7.6 2.1 1 1 0 1 1 1 0 ATP synthase E chain Pkinase PF00069.20 EPX71757.1 - 2.8e-74 249.5 0.0 3.4e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71757.1 - 9.5e-48 162.5 0.0 1.2e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX71757.1 - 7.1e-10 38.3 0.0 5.8e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPX71757.1 - 0.00065 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPX71757.1 - 0.0075 15.6 0.2 0.014 14.7 0.1 1.4 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 EPX71757.1 - 0.011 15.0 0.1 0.055 12.8 0.0 1.9 1 1 1 2 2 2 0 RIO1 family APH PF01636.18 EPX71757.1 - 0.13 12.0 0.4 7.6 6.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 EPX71758.1 - 5.6e-66 221.2 4.0 6.3e-66 221.0 2.8 1.0 1 0 0 1 1 1 1 Peptidase M76 family DUF356 PF04009.7 EPX71758.1 - 0.089 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF356) SprT-like PF10263.4 EPX71758.1 - 0.44 10.1 5.3 0.96 9.0 3.5 1.9 1 1 1 2 2 2 0 SprT-like family UPF0113 PF03657.8 EPX71760.1 - 8.4e-10 38.5 0.0 1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EPX71760.1 - 0.048 13.3 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 PUA domain SRP72 PF08492.7 EPX71761.1 - 1.1e-12 48.1 4.0 2.9e-12 46.7 2.8 1.7 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_11 PF13414.1 EPX71761.1 - 0.0069 16.0 8.0 0.028 14.0 0.0 3.7 5 0 0 5 5 5 1 TPR repeat YfiO PF13525.1 EPX71761.1 - 0.015 14.7 0.2 6.2 6.2 0.0 2.4 1 1 1 2 2 2 0 Outer membrane lipoprotein TPR_14 PF13428.1 EPX71761.1 - 0.021 15.4 0.6 8.9 7.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat bZIP_2 PF07716.10 EPX71761.1 - 0.036 13.8 3.5 0.13 12.0 2.4 2.0 1 0 0 1 1 1 0 Basic region leucine zipper TPR_2 PF07719.12 EPX71761.1 - 0.053 13.4 3.2 5.4 7.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPX71761.1 - 0.098 13.1 1.0 0.78 10.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPX71761.1 - 0.11 12.3 3.3 1.2 9.0 0.1 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EPX71761.1 - 0.25 11.4 6.5 0.46 10.6 0.3 3.9 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Ferrochelatase PF00762.14 EPX71762.1 - 2.8e-92 309.0 0.0 3.3e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase F_bP_aldolase PF01116.15 EPX71762.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.5 1 1 0 1 1 1 0 Fructose-bisphosphate aldolase class-II DUF914 PF06027.7 EPX71763.1 - 1.5e-127 425.0 21.6 1.8e-127 424.8 14.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EPX71763.1 - 1.5e-06 28.3 11.5 1.5e-06 28.3 8.0 2.7 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EPX71763.1 - 0.00011 22.3 8.8 0.00011 22.3 6.1 2.9 3 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EPX71763.1 - 0.0015 18.1 26.3 0.005 16.5 3.3 3.0 2 2 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EPX71763.1 - 0.014 14.3 21.3 0.038 12.9 14.8 1.7 1 1 0 1 1 1 0 UAA transporter family KKLCAg1 PF15204.1 EPX71763.1 - 0.031 14.2 0.1 0.069 13.1 0.1 1.5 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 R3H-assoc PF13902.1 EPX71764.1 - 0.00025 21.0 0.2 0.00049 20.0 0.1 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain DUF4032 PF13224.1 EPX71764.1 - 0.071 12.8 0.2 0.11 12.1 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4032) RRM_1 PF00076.17 EPX71765.1 - 1.7e-16 59.5 0.0 1.1e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX71765.1 - 4.2e-05 23.2 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71765.1 - 0.00017 21.4 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sulfate_transp PF00916.15 EPX71766.1 - 2.5e-44 151.3 12.9 5.7e-44 150.2 8.9 1.6 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 EPX71766.1 - 7.6e-21 73.7 0.1 2e-20 72.3 0.0 1.7 2 0 0 2 2 2 1 STAS domain Sulfate_tra_GLY PF13792.1 EPX71766.1 - 9.5e-21 73.2 5.0 7.4e-20 70.4 3.4 2.7 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif Miro PF08477.8 EPX71767.1 - 1.2e-36 125.8 0.0 1.7e-19 70.4 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EPX71767.1 - 3.6e-30 103.5 0.0 8.6e-30 102.3 0.0 1.7 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EPX71767.1 - 1.5e-27 94.6 0.3 2.7e-27 93.8 0.2 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EPX71767.1 - 1.5e-19 69.9 0.0 9.3e-10 38.1 0.0 2.3 2 0 0 2 2 2 2 Ras family AAA_16 PF13191.1 EPX71767.1 - 6.9e-08 32.6 0.0 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EPX71767.1 - 1.1e-07 31.8 0.0 0.00022 21.1 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EPX71767.1 - 9.5e-07 29.0 0.0 0.01 16.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EPX71767.1 - 1.9e-06 27.1 0.0 0.0038 16.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EPX71767.1 - 4.9e-06 26.4 0.0 0.017 14.8 0.0 2.7 2 0 0 2 2 2 2 Archaeal ATPase EF-hand_7 PF13499.1 EPX71767.1 - 8.6e-06 25.7 3.6 0.095 12.8 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair NACHT PF05729.7 EPX71767.1 - 9.3e-06 25.3 0.0 0.016 14.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain ABC_tran PF00005.22 EPX71767.1 - 1.4e-05 25.4 0.0 0.1 12.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter EF-hand_1 PF00036.27 EPX71767.1 - 1.4e-05 24.0 3.2 0.036 13.3 1.2 3.1 2 0 0 2 2 2 2 EF hand RNA_helicase PF00910.17 EPX71767.1 - 1.9e-05 24.7 0.0 0.73 10.0 0.0 3.6 4 0 0 4 4 3 2 RNA helicase EF-hand_8 PF13833.1 EPX71767.1 - 4.8e-05 22.8 6.1 0.0038 16.8 0.8 3.3 2 1 1 3 3 3 1 EF-hand domain pair MobB PF03205.9 EPX71767.1 - 6.3e-05 22.7 0.1 0.18 11.4 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_21 PF13304.1 EPX71767.1 - 0.00018 21.5 0.3 0.0032 17.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EPX71767.1 - 0.00038 19.9 0.0 0.5 9.7 0.0 3.6 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EPX71767.1 - 0.00041 20.0 0.0 0.24 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPX71767.1 - 0.00044 19.7 0.1 0.17 11.4 0.0 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EPX71767.1 - 0.00056 19.7 0.1 0.028 14.2 0.0 2.5 2 0 0 2 2 2 1 Dynamin family EF-hand_6 PF13405.1 EPX71767.1 - 0.00065 19.3 7.1 0.028 14.3 1.5 3.1 3 0 0 3 3 2 1 EF-hand domain Zeta_toxin PF06414.7 EPX71767.1 - 0.00091 18.3 0.0 0.46 9.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.24 EPX71767.1 - 0.0016 18.6 0.0 2.7 8.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EPX71767.1 - 0.002 17.0 0.0 0.062 12.1 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Septin PF00735.13 EPX71767.1 - 0.0021 17.0 0.0 0.33 9.9 0.0 2.2 2 0 0 2 2 2 1 Septin cobW PF02492.14 EPX71767.1 - 0.0026 17.2 0.0 1.8 7.9 0.0 3.1 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EPX71767.1 - 0.0027 17.5 0.0 2.5 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EPX71767.1 - 0.0033 16.9 0.0 0.31 10.5 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EPX71767.1 - 0.0033 16.3 0.0 0.14 11.0 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EPX71767.1 - 0.0043 16.5 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain EF-hand_5 PF13202.1 EPX71767.1 - 0.0052 16.0 2.8 0.0052 16.0 1.9 2.2 2 0 0 2 2 2 1 EF hand ATP_bind_1 PF03029.12 EPX71767.1 - 0.0065 16.0 0.1 6.8 6.1 0.0 4.0 4 1 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 EPX71767.1 - 0.011 15.7 1.0 1.8 8.4 0.0 3.2 3 1 1 4 4 3 0 AAA domain AAA_15 PF13175.1 EPX71767.1 - 0.015 14.4 1.0 3.6 6.5 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EPX71767.1 - 0.015 15.1 0.0 5.5 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EPX71767.1 - 0.016 15.5 0.3 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain IIGP PF05049.8 EPX71767.1 - 0.026 13.3 0.0 4.7 5.9 0.0 2.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 EPX71767.1 - 0.031 15.0 0.0 17 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 EPX71767.1 - 0.056 12.8 0.4 1.7 8.0 0.0 2.6 3 0 0 3 3 2 0 Guanylate kinase AAA_25 PF13481.1 EPX71767.1 - 0.056 12.8 0.0 23 4.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.14 EPX71767.1 - 0.057 12.6 0.1 5.2 6.2 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EPX71767.1 - 0.06 13.6 0.0 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EPX71767.1 - 0.075 11.9 0.0 0.24 10.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 EPX71767.1 - 0.085 12.0 0.0 0.43 9.6 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Hpr_kinase_C PF07475.7 EPX71767.1 - 0.087 12.1 0.0 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain FtsK_SpoIIIE PF01580.13 EPX71767.1 - 0.11 11.9 0.0 2.9 7.3 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 EPX71767.1 - 0.13 11.6 0.0 11 5.5 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 EPX71767.1 - 0.14 11.8 0.0 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 NTPase Arf PF00025.16 EPX71767.1 - 0.14 11.4 0.0 2.3 7.4 0.0 2.7 3 0 0 3 3 2 0 ADP-ribosylation factor family IstB_IS21 PF01695.12 EPX71767.1 - 0.14 11.5 0.0 4.7 6.5 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SE PF00437.15 EPX71767.1 - 0.18 10.6 0.0 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.4 EPX71767.1 - 0.19 10.3 0.0 4.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.11 EPX71767.1 - 0.2 10.8 0.0 0.45 9.7 0.0 1.5 2 0 0 2 2 1 0 PhoH-like protein Fungal_trans PF04082.13 EPX71768.1 - 7.8e-14 51.1 0.3 2.4e-13 49.5 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX71768.1 - 6.1e-09 35.6 8.4 1.2e-08 34.7 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1980 PF09323.5 EPX71769.1 - 0.83 9.3 6.1 0.11 12.2 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) BATS PF06968.8 EPX71770.1 - 3.8e-25 87.5 0.0 8.9e-25 86.3 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EPX71770.1 - 2e-18 67.1 0.1 3.2e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Smr PF01713.16 EPX71771.1 - 5.5e-14 52.1 0.0 1.5e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Smr domain DUF4224 PF13986.1 EPX71771.1 - 0.1 12.1 0.3 0.83 9.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) PAPS_reduct PF01507.14 EPX71772.1 - 3.1e-35 121.5 0.0 1.2e-33 116.3 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SNF2_N PF00176.18 EPX71773.1 - 3.3e-64 216.5 0.1 4.6e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPX71773.1 - 1.8e-14 53.3 0.1 1.1e-13 50.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX71773.1 - 4.9e-09 36.2 0.4 5.7e-08 32.8 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPX71773.1 - 1.7e-08 34.1 0.0 4.1e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPX71773.1 - 0.0071 16.4 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain VMA21 PF09446.5 EPX71774.1 - 2.7e-12 46.4 6.1 3.4e-12 46.0 4.3 1.1 1 0 0 1 1 1 1 VMA21-like domain DUF1772 PF08592.6 EPX71774.1 - 0.0068 16.1 0.1 0.0072 16.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Silic_transp PF03842.8 EPX71774.1 - 0.017 13.2 0.3 0.019 13.0 0.2 1.1 1 0 0 1 1 1 0 Silicon transporter DUF3262 PF11660.3 EPX71774.1 - 0.45 10.6 3.6 0.57 10.3 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) CENP-Q PF13094.1 EPX71775.1 - 3.4e-15 56.4 8.3 3.4e-15 56.4 5.7 1.5 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Vma12 PF11712.3 EPX71775.1 - 0.082 12.6 0.6 0.14 11.8 0.4 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4314 PF14192.1 EPX71775.1 - 0.11 12.7 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) Tocopherol_cycl PF14249.1 EPX71775.1 - 0.16 10.6 0.2 0.25 9.9 0.0 1.4 2 0 0 2 2 2 0 Tocopherol cyclase DUF573 PF04504.9 EPX71775.1 - 0.27 11.5 6.9 1.4 9.2 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF573 MscS_porin PF12795.2 EPX71775.1 - 1.3 8.3 16.3 0.39 9.9 4.6 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF904 PF06005.7 EPX71775.1 - 5.6 7.3 13.4 1.6 9.0 6.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) WD40 PF00400.27 EPX71776.1 - 1.2e-29 101.0 14.6 7.3e-06 25.6 0.0 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EPX71776.1 - 6e-08 32.6 0.4 0.01 15.5 0.1 3.7 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EPX71776.1 - 0.0017 17.4 1.9 0.066 12.2 1.3 2.5 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal Sec6 PF06046.8 EPX71777.1 - 7.2e-126 420.5 4.1 1e-125 420.0 2.8 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF1193 PF06702.7 EPX71777.1 - 0.011 15.1 0.8 0.021 14.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1193) Pan_kinase PF03309.9 EPX71777.1 - 0.083 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Type III pantothenate kinase MPC PF03650.8 EPX71778.1 - 3.8e-38 130.1 0.1 4.8e-38 129.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF4028 PF13220.1 EPX71778.1 - 0.088 12.4 0.1 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) Fucokinase PF07959.7 EPX71779.1 - 0.0056 15.2 0.0 0.0086 14.6 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase Hydrolase_like2 PF13246.1 EPX71779.1 - 0.037 13.9 0.2 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Ribosomal_L50 PF10501.4 EPX71779.1 - 0.21 11.5 2.2 1.6 8.7 0.8 2.5 2 1 1 3 3 3 0 Ribosomal subunit 39S Sugar_tr PF00083.19 EPX71780.1 - 4e-121 404.7 24.8 4.6e-121 404.5 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPX71780.1 - 4.8e-19 68.2 27.1 1.5e-14 53.4 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EPX71780.1 - 0.011 15.6 1.7 0.022 14.7 0.0 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 MFS_3 PF05977.8 EPX71780.1 - 0.091 10.8 4.9 0.14 10.2 3.4 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector Sugar_tr PF00083.19 EPX71781.1 - 4.5e-117 391.3 27.4 5.3e-117 391.1 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPX71781.1 - 3.9e-18 65.3 30.7 1.8e-13 49.9 6.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EPX71781.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DAGAT PF03982.8 EPX71782.1 - 4.8e-94 314.3 0.0 5.8e-94 314.1 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Herpes_LAMP2 PF06126.6 EPX71782.1 - 0.097 11.0 0.6 0.13 10.6 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Urm1 PF09138.6 EPX71783.1 - 7.2e-30 102.9 0.6 8.4e-30 102.7 0.4 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EPX71783.1 - 5.2e-06 26.8 0.1 6.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 ThiS family zf-RING_2 PF13639.1 EPX71784.1 - 7.7e-13 48.0 10.2 7.7e-13 48.0 7.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPX71784.1 - 6.1e-12 45.3 11.1 6.1e-12 45.3 7.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX71784.1 - 2.5e-10 39.8 8.1 2.5e-10 39.8 5.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX71784.1 - 2.9e-10 39.6 11.6 2.9e-10 39.6 8.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX71784.1 - 2.3e-08 33.6 9.5 2.3e-08 33.6 6.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPX71784.1 - 3.6e-08 33.1 11.3 3.6e-08 33.1 7.8 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPX71784.1 - 2.1e-07 30.5 4.1 4.5e-07 29.4 2.6 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EPX71784.1 - 4.8e-05 23.3 7.1 4.8e-05 23.3 4.9 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EPX71784.1 - 0.00012 21.7 6.3 0.00071 19.3 1.7 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EPX71784.1 - 0.0013 18.5 2.1 0.0039 16.9 1.5 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 EPX71784.1 - 0.0026 17.6 0.1 0.0066 16.3 0.0 1.6 1 0 0 1 1 1 1 U-box domain DUF983 PF06170.7 EPX71784.1 - 0.0044 17.1 1.2 0.073 13.2 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF983) zf-RING_4 PF14570.1 EPX71784.1 - 0.015 14.8 9.5 0.015 14.8 6.6 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.7 EPX71784.1 - 0.024 14.3 14.9 0.38 10.5 5.1 2.4 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.2 EPX71784.1 - 0.075 12.8 16.0 0.56 10.0 0.6 2.8 2 1 1 3 3 3 0 Double zinc ribbon zf-AN1 PF01428.11 EPX71784.1 - 5.7 6.8 14.7 2.8 7.8 1.3 3.0 2 1 1 3 3 3 0 AN1-like Zinc finger Rep_fac-A_C PF08646.5 EPX71784.1 - 8.9 6.0 7.3 0.98 9.1 0.3 2.4 2 0 0 2 2 2 0 Replication factor-A C terminal domain Sugar_tr PF00083.19 EPX71785.1 - 1.3e-120 403.1 25.6 1.5e-120 402.8 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPX71785.1 - 4.8e-19 68.2 26.6 1e-13 50.7 7.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EPX71785.1 - 0.098 12.6 0.1 0.098 12.6 0.1 2.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF1129 PF06570.6 EPX71786.1 - 0.57 9.4 3.0 0.78 9.0 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Tic20 PF09685.5 EPX71786.1 - 0.75 9.8 13.3 0.061 13.3 5.4 1.8 1 1 1 2 2 2 0 Tic20-like protein Polysacc_synt_C PF14667.1 EPX71787.1 - 0.68 9.7 11.5 1.3 8.7 8.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF912 PF06024.7 EPX71787.1 - 2.1 8.4 4.5 7.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0104 PF03706.8 EPX71787.1 - 2.8 7.1 8.8 2.9 7.0 0.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0104) WTF PF03303.8 EPX71790.1 - 0.097 12.0 4.9 0.2 11.0 3.4 1.6 1 1 0 1 1 1 0 WTF protein MFS_1 PF07690.11 EPX71791.1 - 2.3e-38 131.8 22.1 2.3e-38 131.8 15.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX71791.1 - 6.7e-12 44.7 6.9 6.7e-12 44.7 4.8 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EPX71791.1 - 0.0002 19.7 1.4 0.00033 18.9 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EPX71791.1 - 0.00056 18.1 0.2 0.00089 17.4 0.2 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector UNC-93 PF05978.11 EPX71791.1 - 0.014 14.8 1.1 0.014 14.8 0.8 2.3 3 1 0 3 3 3 0 Ion channel regulatory protein UNC-93 OATP PF03137.15 EPX71791.1 - 0.95 7.4 8.4 2.5 6.0 2.8 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FANCL_C PF11793.3 EPX71792.1 - 0.058 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain MFS_1 PF07690.11 EPX71793.1 - 1.3e-35 122.7 32.0 1.3e-35 122.7 22.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX71793.1 - 7.1e-09 34.7 24.8 2.8e-07 29.4 17.1 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter SLAC1 PF03595.12 EPX71794.1 - 1.1e-68 231.3 45.2 1.2e-68 231.1 31.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel 2-oxoacid_dh PF00198.18 EPX71795.1 - 8.3e-83 277.1 0.1 1.1e-82 276.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 EPX71795.1 - 6.8e-18 64.0 0.1 1.6e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.17 EPX71795.1 - 1.4e-17 63.0 0.4 3.9e-17 61.6 0.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme GTP_EFTU PF00009.22 EPX71797.1 - 4.1e-57 192.6 0.0 7.4e-57 191.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPX71797.1 - 3.2e-36 123.4 0.0 8.7e-36 122.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPX71797.1 - 3.8e-16 58.9 1.1 1.1e-15 57.4 0.7 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EPX71797.1 - 6.9e-05 22.4 0.3 0.00022 20.8 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EPX71797.1 - 0.0014 18.5 0.5 0.0043 16.9 0.4 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2419 PF10343.4 EPX71798.1 - 1.1e-14 54.4 0.0 1.9e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Mga PF05043.8 EPX71798.1 - 0.064 13.5 0.0 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Mga helix-turn-helix domain UDPGP PF01704.13 EPX71799.1 - 2.6e-171 569.7 0.1 3.1e-171 569.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Hexapep PF00132.19 EPX71799.1 - 0.28 10.7 3.0 5 6.8 0.3 2.6 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) ENTH PF01417.15 EPX71800.1 - 2.5e-45 153.3 0.4 3.7e-45 152.8 0.3 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EPX71800.1 - 3.5e-05 22.6 0.0 5.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 EPX71800.1 - 0.049 13.2 0.1 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 VHS domain Asp_Glu_race_2 PF14669.1 EPX71800.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative aspartate racemase DSS1_SEM1 PF05160.8 EPX71800.1 - 3 7.6 6.4 12 5.7 4.4 1.9 1 1 0 1 1 1 0 DSS1/SEM1 family Malic_M PF03949.10 EPX71801.1 - 1.1e-84 284.0 0.3 2e-84 283.1 0.1 1.5 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.14 EPX71801.1 - 5e-58 195.6 0.0 7.6e-58 195.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF2299 PF10061.4 EPX71801.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) DGF-1_4 PF11024.3 EPX71803.1 - 0.082 13.3 0.3 0.1 13.0 0.2 1.2 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 MFS_1_like PF12832.2 EPX71804.1 - 2.4e-17 62.4 3.3 2.4e-17 62.4 2.3 4.3 3 1 1 5 5 5 1 MFS_1 like family RAI1 PF08652.6 EPX71804.1 - 0.044 13.5 1.5 0.065 13.0 0.0 2.0 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease TFIIA_gamma_N PF02268.11 EPX71805.1 - 1.7e-27 94.7 0.2 2.5e-27 94.2 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EPX71805.1 - 2.8e-25 87.8 0.8 4e-25 87.3 0.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF3971 PF13116.1 EPX71805.1 - 0.08 12.3 0.0 0.096 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function Epimerase_Csub PF13950.1 EPX71805.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit GPI-anchored PF10342.4 EPX71806.1 - 1.8e-09 37.9 1.6 1.8e-09 37.9 1.1 2.3 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CAT PF00302.13 EPX71806.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase DNA_pol_E_B PF04042.11 EPX71807.1 - 4.4e-41 140.4 0.5 6.8e-41 139.8 0.4 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 EPX71807.1 - 3.4e-38 131.6 3.5 3e-36 125.2 2.4 2.2 1 1 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal GTP_EFTU PF00009.22 EPX71808.1 - 9.5e-53 178.4 0.0 1.9e-52 177.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EPX71808.1 - 3e-13 49.4 0.1 1.5e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPX71808.1 - 1.5e-09 37.8 0.0 4.1e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EPX71808.1 - 2.5e-08 33.6 0.0 5.5e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EPX71808.1 - 0.00014 21.4 0.0 0.0012 18.3 0.0 2.6 1 1 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EPX71808.1 - 0.0003 20.7 0.1 0.00074 19.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IMS PF00817.15 EPX71809.1 - 1.6e-43 148.0 1.7 5.8e-43 146.2 0.1 2.5 3 0 0 3 3 3 1 impB/mucB/samB family IMS_C PF11799.3 EPX71809.1 - 6.2e-17 61.7 1.3 2.7e-16 59.6 0.4 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EPX71809.1 - 0.008 16.1 0.1 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif VWA PF00092.23 EPX71809.1 - 0.016 14.9 1.0 0.96 9.1 0.1 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain DUF2338 PF10100.4 EPX71809.1 - 0.033 12.5 1.2 0.071 11.4 0.0 2.0 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2338) Protoglobin PF11563.3 EPX71809.1 - 0.036 13.7 1.1 6.5 6.3 0.1 2.5 2 0 0 2 2 2 0 Protoglobin PolyA_pol PF01743.15 EPX71809.1 - 0.061 13.5 0.0 0.27 11.4 0.0 2.1 1 0 0 1 1 1 0 Poly A polymerase head domain Ribophorin_II PF05817.9 EPX71810.1 - 3.4e-16 58.6 0.9 4e-16 58.3 0.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Ribosomal_S8 PF00410.14 EPX71811.1 - 5.6e-22 77.9 0.0 7.2e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 RNA_pol_Rpc34 PF05158.7 EPX71811.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit Translin PF01997.11 EPX71812.1 - 4.6e-45 153.6 0.8 5.7e-45 153.3 0.5 1.1 1 0 0 1 1 1 1 Translin family Ebola_NP PF05505.7 EPX71812.1 - 0.0097 14.0 0.1 0.19 9.7 0.2 2.0 2 0 0 2 2 2 2 Ebola nucleoprotein RNase_P_pop3 PF08228.6 EPX71812.1 - 0.028 14.2 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 Zein-binding PF04576.10 EPX71812.1 - 0.044 13.8 2.2 2.3 8.4 1.5 2.5 2 0 0 2 2 2 0 Zein-binding LAG1-DNAbind PF09271.6 EPX71813.1 - 3.4e-24 85.9 5.0 4.2e-23 82.3 1.5 2.9 2 1 0 2 2 2 1 LAG1, DNA binding BTD PF09270.5 EPX71813.1 - 2.7e-20 72.6 0.3 6.9e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 Beta-trefoil DNA-binding domain DUF3835 PF12927.2 EPX71814.1 - 8.7e-08 33.0 1.5 8.7e-08 33.0 1.0 5.7 4 2 1 5 5 5 2 Domain of unknown function (DUF3835) tRNA-synt_2 PF00152.15 EPX71815.1 - 7.1e-117 389.9 0.0 9.5e-117 389.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPX71815.1 - 2.9e-05 23.8 0.2 0.00057 19.7 0.1 2.7 2 1 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EPX71815.1 - 3e-05 23.6 0.0 0.019 14.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) DIX PF00778.12 EPX71815.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 DIX domain DUF4131 PF13567.1 EPX71815.1 - 0.088 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Glyco_transf_34 PF05637.7 EPX71816.1 - 7.6e-77 258.0 0.8 1e-76 257.5 0.5 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family tRNA-synt_2d PF01409.15 EPX71817.1 - 1.5e-48 165.2 0.1 6.2e-27 94.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EPX71817.1 - 4.1e-25 87.7 0.5 9.8e-25 86.5 0.1 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 EPX71817.1 - 0.049 12.4 1.9 0.14 10.9 0.1 2.3 3 0 0 3 3 3 0 tRNA synthetases class II (D, K and N) Bunya_NS-S PF01104.12 EPX71818.1 - 0.028 13.8 0.2 0.053 13.0 0.1 1.5 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s GST_C_3 PF14497.1 EPX71818.1 - 0.054 13.9 0.0 0.52 10.8 0.0 2.2 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF2439 PF10382.4 EPX71819.1 - 4.3e-22 78.1 0.7 9.6e-22 76.9 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) CN_hydrolase PF00795.17 EPX71820.1 - 2.8e-29 101.7 0.0 4.5e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EPX71820.1 - 3.5e-23 81.7 0.0 9.1e-23 80.4 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 EPX71820.1 - 0.023 14.2 0.0 0.073 12.5 0.0 1.7 2 0 0 2 2 2 0 Asparagine synthase AAA PF00004.24 EPX71821.1 - 1.1e-51 174.4 0.0 2.5e-39 134.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EPX71821.1 - 1.4e-15 57.0 0.0 3.6e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EPX71821.1 - 9.2e-10 38.7 4.1 0.0011 19.0 0.1 3.7 2 2 1 3 3 3 2 AAA ATPase domain NACHT PF05729.7 EPX71821.1 - 5.3e-08 32.7 1.2 0.027 14.1 0.2 4.4 4 1 0 4 4 3 2 NACHT domain AAA_14 PF13173.1 EPX71821.1 - 3.7e-07 30.0 0.0 0.0082 16.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EPX71821.1 - 1.1e-05 25.2 0.0 0.091 12.4 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPX71821.1 - 1.8e-05 24.8 0.1 1.2 9.2 0.0 3.9 2 1 2 4 4 4 2 AAA domain AAA_17 PF13207.1 EPX71821.1 - 2.3e-05 25.1 0.0 0.23 12.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EPX71821.1 - 2.8e-05 23.6 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 EPX71821.1 - 3.5e-05 23.6 0.1 0.48 10.0 0.0 3.6 2 1 1 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 EPX71821.1 - 5.4e-05 22.6 0.1 4.3 6.6 0.0 4.4 3 1 1 4 4 4 1 AAA domain ABC_tran PF00005.22 EPX71821.1 - 0.00013 22.2 0.0 0.46 10.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_33 PF13671.1 EPX71821.1 - 0.00033 20.5 0.0 0.57 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 EPX71821.1 - 0.00035 20.2 0.1 0.29 10.7 0.0 2.5 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_24 PF13479.1 EPX71821.1 - 0.00036 20.1 0.5 0.67 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPX71821.1 - 0.00043 20.6 0.0 0.31 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EPX71821.1 - 0.00048 19.1 0.0 0.1 11.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EPX71821.1 - 0.0011 18.4 0.0 2.4 7.6 0.0 2.7 3 0 0 3 3 3 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 EPX71821.1 - 0.0012 18.0 0.0 0.35 9.9 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 EPX71821.1 - 0.0019 18.3 0.0 0.57 10.3 0.0 3.0 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 EPX71821.1 - 0.0071 16.2 0.0 0.027 14.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) UPF0079 PF02367.12 EPX71821.1 - 0.0099 15.5 0.0 4.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 EPX71821.1 - 0.015 15.3 0.0 3.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EPX71821.1 - 0.019 14.5 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SRPRB PF09439.5 EPX71821.1 - 0.019 14.1 0.2 0.27 10.4 0.1 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RuvB_N PF05496.7 EPX71821.1 - 0.024 13.6 0.0 0.086 11.8 0.0 1.9 2 1 0 2 2 1 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EPX71821.1 - 0.026 13.2 0.0 3.6 6.1 0.0 2.3 2 0 0 2 2 2 0 TIP49 C-terminus PduV-EutP PF10662.4 EPX71821.1 - 0.031 13.7 0.1 9.7 5.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.16 EPX71821.1 - 0.035 13.2 0.0 8.5 5.4 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 EPX71821.1 - 0.071 12.8 0.2 0.93 9.2 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EPX71821.1 - 0.088 11.6 1.3 1.2 7.9 0.0 2.8 3 1 0 3 3 3 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 EPX71821.1 - 0.11 11.9 0.0 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EPX71821.1 - 0.11 12.0 0.1 8.9 5.9 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EPX71821.1 - 0.16 11.8 0.1 10 6.0 0.1 2.6 3 0 0 3 3 2 0 AAA domain Pro_isomerase PF00160.16 EPX71822.1 - 2.6e-46 157.6 0.0 5.1e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EPX71822.1 - 1.6e-07 30.8 1.6 0.011 15.6 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat Piwi PF02171.12 EPX71823.1 - 4e-94 314.9 0.0 6.1e-94 314.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EPX71823.1 - 2.6e-23 81.7 0.3 4.8e-23 80.9 0.2 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EPX71823.1 - 3.1e-20 71.2 0.4 8e-20 69.9 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) YTH PF04146.10 EPX71824.1 - 1.4e-15 57.1 0.0 2.1e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain adh_short PF00106.20 EPX71825.1 - 4.1e-16 59.3 0.0 6.9e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPX71825.1 - 4.8e-06 26.3 0.0 8.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPX71825.1 - 6.7e-05 22.7 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPX71825.1 - 0.00053 19.4 0.1 0.00079 18.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPX71825.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding DUF1776 PF08643.5 EPX71825.1 - 0.026 13.6 0.0 0.17 10.9 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.15 EPX71825.1 - 0.099 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EPX71825.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.14 EPX71825.1 - 0.13 11.3 0.0 1.2 8.1 0.0 2.3 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EPX71825.1 - 0.2 11.3 0.1 0.3 10.7 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HEAT PF02985.17 EPX71826.1 - 0.00014 21.6 0.1 5.7 7.2 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat IncA PF04156.9 EPX71826.1 - 0.4 10.2 12.1 0.79 9.2 8.4 1.4 1 0 0 1 1 1 0 IncA protein Pil1 PF13805.1 EPX71827.1 - 2.5e-135 449.8 0.4 3.3e-135 449.4 0.3 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 V_ATPase_I PF01496.14 EPX71827.1 - 0.21 9.3 1.3 0.3 8.8 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1769 PF08588.5 EPX71828.1 - 2e-21 75.6 0.3 4.4e-21 74.5 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF2456 PF10445.4 EPX71829.1 - 1.4e-30 105.0 2.6 1.4e-30 105.0 1.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) DUF1295 PF06966.7 EPX71830.1 - 3.7e-59 199.8 9.1 4.8e-59 199.5 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EPX71830.1 - 0.089 13.0 0.0 0.089 13.0 0.0 2.9 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PHD PF00628.24 EPX71831.1 - 1.9e-12 46.6 6.1 1.9e-12 46.6 4.2 2.2 2 0 0 2 2 2 1 PHD-finger PX PF00787.19 EPX71832.1 - 2.7e-13 49.7 0.0 8.7e-13 48.0 0.0 1.8 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EPX71832.1 - 1.1e-09 37.8 3.9 1.1e-09 37.8 2.7 2.4 3 1 0 3 3 3 1 SNARE domain Ndc1_Nup PF09531.5 EPX71832.1 - 6.7 4.9 9.8 4.9 5.4 5.8 1.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF2929 PF11151.3 EPX71833.1 - 0.35 10.9 7.0 1.5 8.9 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2929) UCR_UQCRX_QCR9 PF05365.7 EPX71834.1 - 5e-23 80.4 2.7 5.5e-23 80.3 1.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like MCM PF00493.18 EPX71835.1 - 4.7e-126 420.0 0.1 7.2e-126 419.4 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPX71835.1 - 4.4e-19 69.1 0.1 1.3e-18 67.6 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPX71835.1 - 7.7e-08 31.7 0.2 1.8e-06 27.2 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EPX71835.1 - 0.0088 15.6 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPX71835.1 - 0.011 15.2 0.0 0.046 13.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain EF-hand_1 PF00036.27 EPX71837.1 - 5.1e-25 84.8 17.2 1.8e-07 29.9 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EPX71837.1 - 7.9e-25 86.7 11.9 1.2e-12 47.7 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EPX71837.1 - 1.6e-23 80.4 11.0 4e-08 32.4 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EPX71837.1 - 8.9e-16 56.4 14.2 0.00045 19.4 0.0 4.6 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.1 EPX71837.1 - 1.3e-14 53.5 15.8 7.2e-08 31.9 0.9 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EPX71837.1 - 2.6e-08 33.6 0.6 0.00028 20.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EPX71837.1 - 3.8e-05 23.3 6.3 0.013 15.2 0.9 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 EPX71837.1 - 0.11 12.1 0.1 0.71 9.4 0.0 2.1 1 1 0 2 2 2 0 Caleosin related protein Metal_resist PF13801.1 EPX71837.1 - 0.38 10.7 3.8 0.15 12.0 0.9 1.7 2 0 0 2 2 2 0 Heavy-metal resistance MgtE_N PF03448.12 EPX71837.1 - 0.88 9.9 6.3 0.32 11.3 1.7 2.1 2 1 0 2 2 2 0 MgtE intracellular N domain DUF3835 PF12927.2 EPX71837.1 - 1.9 9.4 5.2 14 6.7 1.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3835) DUF1040 PF06288.8 EPX71838.1 - 0.15 12.3 1.2 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) Spc97_Spc98 PF04130.8 EPX71839.1 - 8.5e-12 44.1 2.4 1.8e-09 36.4 0.7 2.3 2 0 0 2 2 2 2 Spc97 / Spc98 family CAP_N PF01213.14 EPX71841.1 - 1.8e-114 382.2 1.2 2.7e-114 381.6 0.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EPX71841.1 - 1e-57 193.8 6.8 1.6e-57 193.3 4.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EPX71841.1 - 0.00024 20.5 6.1 0.00049 19.4 4.2 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C Ldh_1_N PF00056.18 EPX71842.1 - 1.3e-40 138.4 0.0 2.2e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EPX71842.1 - 8.6e-38 129.7 0.0 1.1e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EPX71842.1 - 0.00014 20.7 0.0 0.00019 20.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EPX71842.1 - 0.0019 18.0 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EPX71842.1 - 0.012 15.9 0.0 0.037 14.3 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EPX71842.1 - 0.029 13.4 0.0 0.26 10.3 0.0 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.11 EPX71842.1 - 0.16 11.2 0.1 12 5.1 0.0 2.4 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase NAD_binding_10 PF13460.1 EPX71842.1 - 1.4 8.8 4.1 1 9.3 0.4 2.4 2 1 0 2 2 2 0 NADH(P)-binding Ribosomal_L1 PF00687.16 EPX71843.1 - 1.6e-34 119.2 0.9 2.1e-34 118.8 0.2 1.5 1 1 1 2 2 2 1 Ribosomal protein L1p/L10e family DnaI_N PF07319.6 EPX71843.1 - 0.5 10.6 3.9 14 6.0 0.1 3.3 2 1 1 3 3 3 0 Primosomal protein DnaI N-terminus ATP-synt_S1 PF05827.7 EPX71844.1 - 7.7e-32 110.7 4.9 8.9e-32 110.5 3.4 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) INSIG PF07281.7 EPX71845.1 - 4.3e-40 137.1 4.1 5.2e-40 136.8 2.8 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) N-SET PF11764.3 EPX71846.1 - 2.6e-28 99.0 0.0 2.6e-28 99.0 0.0 3.2 3 1 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 EPX71846.1 - 2.6e-24 86.3 0.5 2.6e-24 86.3 0.3 3.0 3 1 0 3 3 3 1 SET domain SET_assoc PF11767.3 EPX71846.1 - 5.2e-19 67.3 1.7 5.2e-19 67.3 1.2 2.0 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.17 EPX71846.1 - 6.3e-11 41.7 0.1 3.4e-08 33.0 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71846.1 - 1.9e-08 34.1 0.0 2.7e-06 27.2 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cnd2 PF05786.9 EPX71847.1 - 5.1e-161 537.7 15.1 6.3e-161 537.4 10.4 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF778 PF05608.7 EPX71847.1 - 0.0073 16.2 0.3 0.069 13.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF778) PRA1 PF03208.14 EPX71848.1 - 8.4e-32 109.6 0.1 1e-31 109.3 0.1 1.1 1 0 0 1 1 1 1 PRA1 family protein AAA PF00004.24 EPX71849.1 - 3.5e-43 146.9 0.0 5.6e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPX71849.1 - 2e-07 31.1 0.0 1.3e-05 25.2 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EPX71849.1 - 9.4e-07 28.6 0.4 5.1e-05 23.0 0.1 3.0 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EPX71849.1 - 1.8e-06 27.1 0.0 3.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EPX71849.1 - 2.5e-05 24.4 0.0 0.0029 17.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EPX71849.1 - 3.4e-05 23.8 0.0 9.7e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EPX71849.1 - 6e-05 23.8 0.1 0.00019 22.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPX71849.1 - 0.00026 20.6 0.1 0.00055 19.6 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EPX71849.1 - 0.00064 20.0 0.1 0.0022 18.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EPX71849.1 - 0.00086 18.1 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EPX71849.1 - 0.0012 18.6 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPX71849.1 - 0.0017 17.8 0.2 0.011 15.1 0.1 2.1 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EPX71849.1 - 0.0031 16.9 0.1 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EPX71849.1 - 0.0048 16.0 0.2 0.012 14.7 0.0 1.7 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EPX71849.1 - 0.0052 15.7 0.0 0.01 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EPX71849.1 - 0.0098 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPX71849.1 - 0.014 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPX71849.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EPX71849.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EPX71849.1 - 0.022 13.8 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.11 EPX71849.1 - 0.023 13.9 0.1 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 EPX71849.1 - 0.025 13.7 0.0 0.17 10.9 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_24 PF13479.1 EPX71849.1 - 0.026 14.1 0.4 0.052 13.1 0.1 1.6 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EPX71849.1 - 0.04 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EPX71849.1 - 0.04 13.3 0.0 0.22 10.9 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EPX71849.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EPX71849.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PXA PF02194.10 EPX71850.1 - 6.5e-24 84.5 4.6 8.8e-24 84.0 0.3 2.7 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 EPX71850.1 - 4.5e-06 26.7 0.2 0.01 15.8 0.0 2.7 2 0 0 2 2 2 2 Sorting nexin C terminal PX PF00787.19 EPX71850.1 - 1.6e-05 24.6 0.2 6.1e-05 22.7 0.1 2.1 1 0 0 1 1 1 1 PX domain Ribosomal_L19e PF01280.15 EPX71851.1 - 2.1e-61 206.0 10.0 2.1e-61 206.0 6.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e DUF3035 PF11233.3 EPX71851.1 - 1.5 8.8 5.6 0.98 9.4 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) SWIRM PF04433.12 EPX71852.1 - 9.1e-16 57.7 0.0 2.4e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 SWIRM domain UCH PF00443.24 EPX71853.1 - 1e-60 205.1 1.3 1.4e-60 204.7 0.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPX71853.1 - 1.1e-24 87.3 1.1 2.2e-24 86.4 0.8 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3287 PF11690.3 EPX71853.1 - 0.015 15.3 0.1 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) DUF2296 PF10058.4 EPX71853.1 - 0.016 14.9 1.8 0.6 9.9 0.3 3.2 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Peptidase_C98 PF15499.1 EPX71853.1 - 0.021 14.1 5.3 0.15 11.3 0.8 3.5 2 1 1 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Choline_transpo PF04515.7 EPX71854.1 - 6.3e-08 31.7 42.5 3.7e-07 29.1 16.4 3.2 2 1 2 4 4 4 2 Plasma-membrane choline transporter MitMem_reg PF13012.1 EPX71855.1 - 3.1e-35 120.7 0.5 5.9e-35 119.8 0.0 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EPX71855.1 - 2.5e-26 91.6 0.0 5.4e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mito_carr PF00153.22 EPX71856.1 - 7.1e-26 89.7 2.4 8.9e-15 54.1 0.1 3.5 3 2 0 3 3 3 3 Mitochondrial carrier protein PUF PF00806.14 EPX71857.1 - 2.6e-37 124.1 6.9 1.6e-06 27.2 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Ssl1 PF04056.9 EPX71858.1 - 4.2e-85 284.2 0.2 5.5e-85 283.8 0.2 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EPX71858.1 - 2.9e-17 62.3 16.5 2.9e-17 62.3 11.5 2.8 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EPX71858.1 - 7e-08 32.7 0.0 9.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EPX71858.1 - 0.0039 16.9 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zinc_ribbon_4 PF13717.1 EPX71858.1 - 0.49 10.1 11.6 1.6 8.5 1.0 3.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EPX71858.1 - 1.2 8.8 12.3 3 7.5 1.4 3.6 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.16 EPX71858.1 - 7.8 6.4 26.1 0.037 13.9 7.2 2.9 2 1 0 2 2 2 0 IBR domain RIX1 PF08167.7 EPX71859.1 - 1.3e-40 138.7 4.8 1.3e-40 138.7 3.4 2.9 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis HD_3 PF13023.1 EPX71860.1 - 8.7e-42 142.6 0.6 1.1e-41 142.3 0.4 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EPX71860.1 - 6e-06 26.2 0.9 1e-05 25.4 0.6 1.4 1 0 0 1 1 1 1 HD domain HD_2 PF12917.2 EPX71860.1 - 0.009 15.8 0.3 0.011 15.4 0.2 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme Streptin-Immun PF11083.3 EPX71860.1 - 0.08 12.9 1.1 0.13 12.2 0.8 1.3 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein dCMP_cyt_deam_1 PF00383.17 EPX71861.1 - 1.1e-21 76.4 0.1 1.5e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Methyltransf_16 PF10294.4 EPX71861.1 - 4.3e-18 65.3 0.0 6.8e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase APOBEC_N PF08210.6 EPX71861.1 - 0.00082 19.0 0.1 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Methyltransf_31 PF13847.1 EPX71861.1 - 0.0044 16.6 0.0 0.02 14.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Myb_DNA-bind_2 PF08914.6 EPX71861.1 - 0.024 14.4 0.0 0.085 12.6 0.0 1.9 2 0 0 2 2 2 0 Rap1 Myb domain NOT2_3_5 PF04153.13 EPX71862.1 - 3e-34 117.7 1.0 5.4e-34 116.9 0.7 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DnaJ PF00226.26 EPX71863.1 - 7.1e-24 83.3 4.5 1.7e-23 82.0 3.1 1.7 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EPX71863.1 - 5.2e-23 80.7 0.0 7e-18 64.3 0.0 3.0 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EPX71863.1 - 4.2e-11 42.7 13.7 7.6e-11 41.9 9.5 1.4 1 0 0 1 1 1 1 DnaJ central domain CUE PF02845.11 EPX71864.1 - 3.4e-09 36.0 0.0 7.5e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 CUE domain zf-RING_2 PF13639.1 EPX71865.1 - 9.7e-13 47.7 8.8 9.7e-13 47.7 6.1 1.8 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EPX71865.1 - 4.8e-08 33.0 5.8 1.2e-07 31.7 4.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPX71865.1 - 1.6e-06 27.9 8.5 3.5e-06 26.9 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX71865.1 - 4.7e-06 26.1 8.0 1.2e-05 24.8 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX71865.1 - 2.6e-05 23.7 6.2 4.5e-05 23.0 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX71865.1 - 0.00011 21.8 7.8 0.00021 20.9 5.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPX71865.1 - 0.00062 19.5 3.2 0.0013 18.4 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EPX71865.1 - 0.0017 17.8 3.3 0.0034 16.8 2.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EPX71865.1 - 0.076 13.0 8.2 0.15 12.1 5.7 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 EPX71865.1 - 0.48 10.4 7.4 1 9.4 5.1 1.6 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.1 EPX71865.1 - 5.7 6.7 7.5 14 5.5 5.2 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 EPX71865.1 - 5.8 6.6 10.7 2.2 8.0 4.8 2.1 2 0 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.1 EPX71865.1 - 8.6 6.0 7.5 17 5.1 5.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2418 PF10332.4 EPX71866.1 - 2.4e-25 88.7 2.3 2.4e-25 88.7 1.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) DUF3328 PF11807.3 EPX71866.1 - 0.2 11.2 3.3 0.24 11.0 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) BHD_3 PF10405.4 EPX71867.1 - 1e-29 102.0 0.1 2.1e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 EPX71867.1 - 6.9e-26 90.3 1.5 6.9e-26 90.3 1.0 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_2 PF10404.4 EPX71867.1 - 1e-16 60.9 0.2 1e-16 60.9 0.1 3.0 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 EPX71867.1 - 4.5e-16 58.1 0.4 4.5e-16 58.1 0.3 3.3 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 EPX71867.1 - 0.00012 22.2 0.0 0.00036 20.7 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily RabGAP-TBC PF00566.13 EPX71868.1 - 2.4e-33 115.4 0.2 2.3e-32 112.2 0.0 2.7 2 1 0 2 2 2 1 Rab-GTPase-TBC domain PSI_PsaH PF03244.9 EPX71868.1 - 0.042 13.0 0.1 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI Pkinase PF00069.20 EPX71869.1 - 1.8e-67 227.2 0.0 2.3e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71869.1 - 1.7e-29 102.7 0.0 2.2e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX71869.1 - 5.4e-09 35.4 0.0 8e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 EPX71869.1 - 4.6e-05 23.8 0.1 0.00011 22.5 0.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EPX71869.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1977 PF09320.6 EPX71869.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) PHD PF00628.24 EPX71870.1 - 1.6e-10 40.4 7.8 2.6e-10 39.8 5.4 1.3 1 0 0 1 1 1 1 PHD-finger zf-piccolo PF05715.8 EPX71870.1 - 0.012 15.5 3.3 0.012 15.5 2.3 1.8 2 0 0 2 2 2 0 Piccolo Zn-finger zf-PHD-like PF15446.1 EPX71870.1 - 0.013 14.8 3.3 0.034 13.4 2.3 1.8 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 EPX71870.1 - 0.02 14.1 5.9 0.081 12.2 4.1 2.0 1 1 0 1 1 1 0 PHD-finger FYVE_2 PF02318.11 EPX71870.1 - 0.039 13.8 1.4 0.07 13.0 1.0 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger COG5 PF10392.4 EPX71870.1 - 0.054 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Prok-RING_1 PF14446.1 EPX71870.1 - 0.076 12.7 2.2 0.14 11.8 1.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DZR PF12773.2 EPX71870.1 - 0.25 11.1 3.9 0.74 9.6 2.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon Gly-rich_Ago1 PF12764.2 EPX71870.1 - 0.39 11.3 4.6 0.72 10.5 2.2 2.1 1 1 1 2 2 2 0 Glycine-rich region of argonaut C1_1 PF00130.17 EPX71870.1 - 0.39 10.4 6.5 0.11 12.2 1.2 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MRP-L47 PF06984.8 EPX71871.1 - 1e-33 115.0 0.7 1.5e-33 114.4 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) ERCC4 PF02732.10 EPX71872.1 - 3.3e-24 85.2 0.7 9.2e-24 83.8 0.5 1.8 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EPX71872.1 - 0.00046 20.3 0.0 0.0025 17.9 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain HTH_45 PF14947.1 EPX71872.1 - 0.033 13.9 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix Ubie_methyltran PF01209.13 EPX71873.1 - 7.5e-85 283.7 0.0 9.6e-85 283.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EPX71873.1 - 5.5e-17 61.7 0.0 9.5e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX71873.1 - 2.1e-13 50.5 0.0 4.8e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX71873.1 - 3.6e-12 46.6 0.0 6.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX71873.1 - 1e-11 45.3 0.0 2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX71873.1 - 5.9e-11 42.3 0.0 8.9e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX71873.1 - 1.2e-08 35.2 0.0 2.9e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPX71873.1 - 3.6e-08 33.4 0.0 1.1e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EPX71873.1 - 3.6e-05 23.5 0.1 0.021 14.4 0.0 3.1 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 EPX71873.1 - 0.00027 20.6 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EPX71873.1 - 0.024 15.4 0.0 0.055 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 EPX71873.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Pox_MCEL PF03291.11 EPX71873.1 - 0.068 12.0 0.1 0.13 11.0 0.1 1.4 1 0 0 1 1 1 0 mRNA capping enzyme DUF2415 PF10313.4 EPX71874.1 - 4.6e-12 45.4 0.0 2.3e-11 43.1 0.0 2.2 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) Cytochrom_D1 PF02239.11 EPX71874.1 - 0.12 10.6 0.0 0.16 10.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain WD40 PF00400.27 EPX71874.1 - 1.1 9.2 10.9 0.62 10.0 0.2 4.6 6 0 0 6 6 6 0 WD domain, G-beta repeat HIT PF01230.18 EPX71875.1 - 4.6e-19 68.7 0.3 7.9e-17 61.5 0.2 2.4 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPX71875.1 - 0.00028 21.0 0.2 0.0071 16.5 0.1 2.3 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding 2-Hacid_dh_C PF02826.14 EPX71876.1 - 6.3e-50 168.7 0.0 9.5e-50 168.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPX71876.1 - 1.3e-37 128.2 0.0 1.7e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPX71876.1 - 5e-05 23.1 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EPX71876.1 - 0.0045 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAP PF00956.13 EPX71877.1 - 2.8e-78 262.4 7.2 2.8e-78 262.4 5.0 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) CNH PF00780.17 EPX71878.1 - 2.8e-07 30.2 0.3 5.8e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 EPX71878.1 - 0.0011 19.0 0.3 0.0011 19.0 0.2 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EPX71878.1 - 0.0087 16.0 0.6 0.0087 16.0 0.4 3.0 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.7 EPX71879.1 - 2.8e-41 141.2 21.6 2.8e-41 141.2 15.0 6.7 2 1 3 5 5 5 1 CASP C terminal KLRAQ PF10205.4 EPX71879.1 - 0.0018 18.2 7.3 0.0018 18.2 5.1 6.6 4 3 1 6 6 6 1 Predicted coiled-coil domain-containing protein SDH_alpha PF03313.10 EPX71879.1 - 0.99 8.3 4.4 18 4.2 2.8 2.8 2 2 0 2 2 2 0 Serine dehydratase alpha chain Ribosomal_L22 PF00237.14 EPX71880.1 - 3.9e-33 113.5 0.1 5.9e-33 112.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Meiotic_rec114 PF03525.9 EPX71880.1 - 0.009 14.5 0.0 0.0097 14.4 0.0 1.1 1 0 0 1 1 1 1 Meiotic recombination protein rec114 CBF_beta PF02312.12 EPX71880.1 - 0.06 12.9 0.2 0.16 11.5 0.1 1.7 1 1 1 2 2 2 0 Core binding factor beta subunit Es2 PF09751.4 EPX71881.1 - 4.8e-34 118.4 23.9 2.4e-19 70.0 8.1 3.1 1 1 2 3 3 3 3 Nuclear protein Es2 DUF2564 PF10819.3 EPX71881.1 - 0.054 13.6 0.3 0.33 11.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) BRE1 PF08647.6 EPX71883.1 - 1e-12 47.8 9.0 1e-12 47.8 6.3 5.2 4 2 2 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EPX71883.1 - 3e-08 33.5 10.0 7.3e-08 32.3 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX71883.1 - 1.6e-06 27.6 9.4 3.5e-06 26.5 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX71883.1 - 1.5e-05 24.5 9.5 3e-05 23.6 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPX71883.1 - 6.7e-05 22.6 9.8 0.00022 20.9 6.8 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPX71883.1 - 0.00045 19.8 11.7 0.0011 18.6 8.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EPX71883.1 - 0.0013 18.8 6.9 0.0032 17.5 4.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger DUF2674 PF10879.3 EPX71883.1 - 0.036 13.7 0.0 0.15 11.7 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) zf-RING_UBOX PF13445.1 EPX71883.1 - 0.058 13.1 8.0 0.1 12.3 4.1 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EPX71883.1 - 0.22 11.4 10.9 0.27 11.1 5.7 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.9 EPX71883.1 - 0.37 10.3 0.0 0.37 10.3 0.0 5.4 5 0 0 5 5 5 0 Rad50 zinc hook motif Prok-RING_4 PF14447.1 EPX71883.1 - 2.3 7.8 6.0 6.8 6.3 4.2 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EPX71883.1 - 7.2 6.2 12.6 6.7 6.3 7.3 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Sec8_exocyst PF04048.9 EPX71884.1 - 4.4e-34 117.1 1.3 4.4e-34 117.1 0.9 2.5 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Zw10 PF06248.8 EPX71884.1 - 1.7e-07 29.8 0.2 4.2e-07 28.5 0.2 1.6 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 DUF2450 PF10475.4 EPX71884.1 - 1.1e-05 24.5 5.6 1.5e-05 24.0 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) IPK PF03770.11 EPX71885.1 - 2.6e-53 180.5 0.2 1.9e-52 177.8 0.0 2.4 3 0 0 3 3 3 1 Inositol polyphosphate kinase DNMT1-RFD PF12047.3 EPX71886.1 - 1.5e-12 47.3 0.1 2.9e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain RNA12 PF10443.4 EPX71886.1 - 0.037 12.5 0.7 4.9 5.5 0.3 2.2 2 0 0 2 2 2 0 RNA12 protein SURF4 PF02077.10 EPX71887.1 - 2.1e-111 371.5 4.9 2.4e-111 371.3 3.4 1.0 1 0 0 1 1 1 1 SURF4 family YhhN PF07947.9 EPX71887.1 - 0.0064 15.8 3.5 0.0064 15.8 2.5 2.1 1 1 1 2 2 2 1 YhhN-like protein HR_lesion PF05514.6 EPX71887.1 - 2.2 8.1 8.6 0.4 10.5 0.7 2.6 2 1 0 2 2 2 0 HR-like lesion-inducing Ribosomal_L36e PF01158.13 EPX71888.1 - 7.3e-40 134.9 3.9 7.9e-40 134.8 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EPX71888.1 - 0.02 13.9 0.1 0.021 13.9 0.1 1.1 1 0 0 1 1 1 0 LemA family TetR_C_9 PF14514.1 EPX71888.1 - 0.057 13.2 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator, TetR, C-terminal Mob1_phocein PF03637.12 EPX71889.1 - 3.4e-70 235.2 2.7 4.1e-70 235.0 1.9 1.1 1 0 0 1 1 1 1 Mob1/phocein family NAD_binding_1 PF00175.16 EPX71890.1 - 8.9e-30 103.4 0.0 1.5e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EPX71890.1 - 2.8e-29 101.1 0.0 1.8e-28 98.5 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EPX71890.1 - 4.8e-05 23.3 0.0 0.0034 17.3 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EPX71890.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Glyco_hydro_76 PF03663.9 EPX71891.1 - 3.1e-139 464.4 20.9 4.1e-139 464.0 14.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EPX71891.1 - 0.012 14.7 9.9 0.061 12.3 0.4 3.1 1 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Yippee-Mis18 PF03226.9 EPX71892.1 - 1.5e-20 72.9 1.1 2.5e-20 72.3 0.7 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TRAPPC10 PF12584.3 EPX71892.1 - 0.032 13.7 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 ERCC4 PF02732.10 EPX71893.1 - 1.1e-24 86.8 0.0 3.4e-24 85.2 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain DEAD PF00270.24 EPX71894.1 - 1.9e-44 151.1 0.0 2.9e-43 147.2 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX71894.1 - 6e-25 86.9 0.0 1.4e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPX71894.1 - 0.0085 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EPX71894.1 - 0.075 12.8 0.0 0.28 10.9 0.0 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DnaJ PF00226.26 EPX71895.1 - 1.1e-22 79.5 1.0 3.2e-22 78.0 0.7 1.9 1 0 0 1 1 1 1 DnaJ domain Med31 PF05669.7 EPX71896.1 - 7.6e-39 131.5 5.5 9.2e-39 131.3 3.8 1.0 1 0 0 1 1 1 1 SOH1 Oxidored-like PF09791.4 EPX71897.1 - 9.8e-23 79.3 2.0 1.5e-22 78.7 1.4 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF4448 PF14610.1 EPX71898.1 - 1.2e-26 93.3 0.0 1.7e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Tyr-DNA_phospho PF06087.7 EPX71899.1 - 5.2e-101 338.4 2.6 6.2e-64 216.2 0.1 2.5 2 1 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EPX71899.1 - 0.02 14.6 0.1 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 PLD-like domain C2 PF00168.25 EPX71900.1 - 6.8e-24 83.5 0.0 1.1e-15 57.2 0.0 2.8 2 0 0 2 2 2 2 C2 domain GTP_EFTU PF00009.22 EPX71901.1 - 2.9e-61 206.2 0.1 4.2e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EPX71901.1 - 9.3e-36 122.0 0.0 2.4e-35 120.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EPX71901.1 - 3.6e-19 68.4 0.0 9.1e-19 67.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EPX71901.1 - 9.5e-14 51.0 0.0 2.3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EPX71901.1 - 2.6e-12 46.6 1.6 4.4e-12 45.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPX71901.1 - 6.2e-05 22.9 0.1 0.00013 21.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAP_assoc PF03828.14 EPX71901.1 - 0.054 13.4 0.2 0.2 11.6 0.1 2.0 1 0 0 1 1 1 0 Cid1 family poly A polymerase Ribosomal_L35Ae PF01247.13 EPX71902.1 - 1.1e-38 130.9 0.2 1.2e-38 130.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EPX71902.1 - 0.0012 18.6 0.0 0.57 10.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain C2 PF00168.25 EPX71903.1 - 1.2e-35 121.2 5.3 1.2e-13 50.6 0.1 5.2 5 0 0 5 5 5 4 C2 domain DUF2404 PF10296.4 EPX71903.1 - 0.1 12.7 0.0 0.43 10.7 0.0 2.1 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) BIR PF00653.16 EPX71904.1 - 3.5e-39 133.0 7.1 1.2e-20 73.6 0.2 2.9 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain Arm PF00514.18 EPX71905.1 - 1.3e-88 288.1 14.7 2.7e-13 49.1 0.0 9.0 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 EPX71905.1 - 3.5e-25 88.0 6.9 5.4e-25 87.4 4.8 1.3 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 EPX71905.1 - 1.3e-21 76.6 0.0 3.8e-07 30.3 0.0 5.2 2 1 0 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 EPX71905.1 - 1.4e-18 66.8 1.2 9.6e-08 32.3 0.0 6.0 7 2 0 7 7 5 3 HEAT-like repeat HEAT PF02985.17 EPX71905.1 - 9.8e-15 53.2 0.0 3.6e-05 23.4 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat Arm_2 PF04826.8 EPX71905.1 - 2.3e-07 30.1 0.0 0.086 11.9 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like CTNNBL PF08216.6 EPX71905.1 - 4.8e-06 26.1 0.3 6.5 6.3 0.0 5.5 5 1 1 6 6 6 2 Catenin-beta-like, Arm-motif containing nuclear Proteasom_PSMB PF10508.4 EPX71905.1 - 1.8e-05 23.1 0.1 0.12 10.6 0.0 3.2 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 EPX71905.1 - 5.2e-05 23.1 0.0 0.95 9.3 0.0 4.8 3 3 1 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.1 EPX71905.1 - 0.0012 18.7 4.6 1.6 8.7 0.1 4.6 3 2 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 SEN1_N PF12726.2 EPX71905.1 - 0.023 12.8 0.0 8 4.3 0.0 3.1 3 0 0 3 3 3 0 SEN1 N terminal HEAT_PBS PF03130.11 EPX71905.1 - 0.03 14.7 0.0 1.5 9.4 0.0 3.6 4 0 0 4 4 2 0 PBS lyase HEAT-like repeat DUF3552 PF12072.3 EPX71905.1 - 0.03 13.5 7.0 0.053 12.7 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Neurokinin_B PF03823.9 EPX71905.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Neurokinin B Acetyltransf_7 PF13508.1 EPX71906.1 - 2.9e-14 52.9 0.1 4.6e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPX71906.1 - 2.7e-07 30.5 0.1 4.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPX71906.1 - 4e-06 26.9 0.0 4.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EPX71906.1 - 0.00033 21.1 2.7 0.006 17.1 0.2 2.4 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EPX71906.1 - 0.012 14.8 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 FR47 PF08445.5 EPX71906.1 - 0.03 14.0 0.0 0.051 13.3 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Ribosomal_L7Ae PF01248.21 EPX71907.1 - 5e-28 96.4 0.8 6.2e-28 96.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RuvA_C PF07499.8 EPX71907.1 - 0.33 11.1 0.1 0.33 11.1 0.1 2.2 3 0 0 3 3 3 0 RuvA, C-terminal domain XPG_I_2 PF12813.2 EPX71908.1 - 1e-46 159.4 0.0 1.5e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EPX71908.1 - 0.019 15.0 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 XPG I-region zf-CCHC PF00098.18 EPX71909.1 - 1.1e-10 40.9 10.0 9.8e-06 25.2 0.7 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EPX71909.1 - 6.5e-06 25.7 0.1 1.1e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EPX71909.1 - 1.9e-05 24.3 3.4 0.0053 16.4 0.5 2.4 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EPX71909.1 - 2.1e-05 24.0 0.2 4.4e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 EPX71909.1 - 0.0019 17.8 10.9 0.2 11.3 0.3 3.8 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 EPX71909.1 - 0.002 17.7 6.0 0.27 10.9 0.5 2.5 2 0 0 2 2 2 2 Zinc knuckle Zn_Tnp_IS1595 PF12760.2 EPX71909.1 - 8.3 6.3 6.8 21 4.9 0.5 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain PHP PF02811.14 EPX71910.1 - 5.5e-16 58.8 0.4 8.7e-16 58.1 0.3 1.3 1 0 0 1 1 1 1 PHP domain Nsp1_C PF05064.8 EPX71911.1 - 0.00045 19.8 4.1 0.0045 16.6 0.9 2.5 2 0 0 2 2 2 1 Nsp1-like C-terminal region Uds1 PF15456.1 EPX71911.1 - 0.0035 17.3 7.7 0.01 15.8 0.2 2.7 2 1 1 3 3 3 1 Up-regulated During Septation Seryl_tRNA_N PF02403.17 EPX71911.1 - 0.037 14.0 4.3 0.14 12.1 2.8 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PC-Esterase PF13839.1 EPX71911.1 - 0.045 13.5 0.1 0.061 13.1 0.1 1.2 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF3408 PF11888.3 EPX71911.1 - 0.051 13.5 0.3 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Phi-29_GP4 PF05464.6 EPX71911.1 - 0.074 12.9 0.3 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Imm31 PF15595.1 EPX71911.1 - 0.087 12.6 1.7 0.31 10.8 0.4 2.3 2 1 1 3 3 3 0 Immunity protein 31 PilJ PF13675.1 EPX71911.1 - 0.09 13.0 0.4 0.23 11.8 0.1 1.9 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF837 PF05769.6 EPX71911.1 - 0.25 10.8 0.1 0.25 10.8 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF837) DUF4164 PF13747.1 EPX71911.1 - 0.71 10.0 10.5 1.4 9.1 0.8 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.7 EPX71911.1 - 0.78 10.0 3.7 1.7 8.9 1.3 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2408 PF10303.4 EPX71911.1 - 1.8 8.6 8.2 2.6 8.1 4.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Nup54 PF13874.1 EPX71911.1 - 2.3 7.8 9.6 2 8.0 1.4 2.8 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Amidohydro_1 PF01979.15 EPX71912.1 - 2e-44 152.6 0.0 2.6e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EPX71912.1 - 6.2e-08 33.0 0.1 2.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EPX71912.1 - 4e-07 29.5 1.0 5.6e-05 22.5 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 EPX71912.1 - 0.015 15.0 0.0 0.044 13.6 0.0 1.9 1 0 0 1 1 1 0 Amidohydrolase A_deaminase PF00962.17 EPX71912.1 - 0.022 13.6 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase CHCH PF06747.8 EPX71913.1 - 5.6e-09 35.6 3.9 7.8e-09 35.2 2.7 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EPX71913.1 - 0.0086 16.0 3.9 0.017 15.1 2.7 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EPX71913.1 - 0.014 15.1 1.8 0.11 12.3 1.6 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 EPX71913.1 - 0.057 13.2 3.6 2.7 7.9 0.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EPX71913.1 - 0.41 10.7 4.4 3.2 7.8 2.1 2.5 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) tRNA-synt_1b PF00579.20 EPX71914.1 - 2.1e-68 230.5 0.0 2.9e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) FAM176 PF14851.1 EPX71914.1 - 8.8 5.9 6.1 1.2e+02 2.2 0.0 2.2 2 0 0 2 2 2 0 FAM176 family His_Phos_2 PF00328.17 EPX71915.1 - 7.6e-117 390.5 2.0 9.8e-117 390.1 1.4 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EPX71915.1 - 2.2e-05 24.0 0.0 4.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 EPX71916.1 - 9.7e-71 237.6 4.3 1.4e-70 237.0 3.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EPX71916.1 - 6.9e-21 73.3 16.6 1.1e-08 34.6 0.3 8.7 8 0 0 8 8 8 4 WD domain, G-beta repeat Nup160 PF11715.3 EPX71916.1 - 4e-06 25.2 1.8 0.05 11.7 0.1 3.4 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPX71916.1 - 0.00022 20.1 6.0 0.17 10.6 0.2 3.9 2 1 2 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EPX71916.1 - 0.00022 19.6 0.1 0.00065 18.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.6 EPX71916.1 - 0.0051 16.5 0.2 0.78 9.4 0.0 3.8 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.10 EPX71916.1 - 0.06 12.4 0.1 0.26 10.3 0.0 2.1 3 0 0 3 3 3 0 CPSF A subunit region ALS_ss_C PF10369.4 EPX71916.1 - 0.14 11.9 0.0 0.55 9.9 0.0 2.0 2 0 0 2 2 2 0 Small subunit of acetolactate synthase TFIIE_beta PF02186.10 EPX71917.1 - 1.9e-24 85.4 0.9 3.4e-24 84.6 0.6 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain Clathrin PF00637.15 EPX71917.1 - 0.04 13.5 0.1 0.091 12.3 0.0 1.6 1 1 0 1 1 1 0 Region in Clathrin and VPS Abhydrolase_1 PF00561.15 EPX71918.1 - 4.6e-20 72.1 0.5 7e-20 71.5 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EPX71918.1 - 8e-20 69.9 0.0 1.5e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EPX71918.1 - 1.2e-09 38.3 0.0 2.3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPX71918.1 - 1e-06 28.5 0.0 3.6e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EPX71918.1 - 7e-05 22.3 0.4 0.15 11.5 0.0 2.7 2 1 1 3 3 3 2 Serine hydrolase (FSH1) Esterase PF00756.15 EPX71918.1 - 0.021 14.2 0.2 0.045 13.1 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.11 EPX71918.1 - 0.069 12.5 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 EPX71918.1 - 0.11 11.8 0.0 8.6 5.5 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family WD40 PF00400.27 EPX71919.1 - 1.2e-38 129.6 6.5 6e-08 32.2 0.2 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EPX71919.1 - 6e-31 106.1 0.4 1.1e-30 105.3 0.3 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex P5-ATPase PF12409.3 EPX71920.1 - 1.4e-33 115.2 0.5 1.9e-32 111.5 0.0 2.9 3 0 0 3 3 3 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 EPX71920.1 - 5.2e-31 107.4 0.2 1.5e-30 105.9 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EPX71920.1 - 4e-23 82.5 0.0 6.6e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPX71920.1 - 4.3e-11 43.6 0.0 1.1e-07 32.5 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPX71920.1 - 0.0001 22.1 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EPX71920.1 - 0.00043 19.6 0.0 0.00096 18.5 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPX71920.1 - 0.17 11.3 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF410 PF04190.8 EPX71921.1 - 1.1e-64 218.5 0.0 1.2e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Sec15 PF04091.7 EPX71922.1 - 2.5e-67 227.4 1.8 2.5e-67 227.4 1.2 2.1 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like TPR_MLP1_2 PF07926.7 EPX71922.1 - 0.00078 19.1 0.8 0.003 17.2 0.6 2.0 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Sec8_exocyst PF04048.9 EPX71922.1 - 0.0016 18.0 3.2 0.0053 16.3 2.2 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Baculo_PEP_C PF04513.7 EPX71922.1 - 0.14 11.9 6.7 0.63 9.8 4.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EPX71922.1 - 0.17 11.4 8.1 0.38 10.3 5.6 1.5 1 0 0 1 1 1 0 IncA protein Med4 PF10018.4 EPX71922.1 - 0.53 9.6 5.1 0.45 9.8 1.5 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 GST_C PF00043.20 EPX71923.1 - 1.4e-11 44.2 0.1 3e-11 43.1 0.0 1.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPX71923.1 - 2.6e-08 33.6 0.0 5.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPX71923.1 - 3.1e-06 27.5 0.1 2e-05 24.9 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPX71923.1 - 1.5e-05 25.0 0.0 3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPX71923.1 - 0.00042 20.4 0.0 0.00096 19.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Frataxin_Cyay PF01491.11 EPX71924.1 - 1.4e-35 121.3 0.0 1.7e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Pet127 PF08634.5 EPX71925.1 - 1.8e-103 345.4 3.9 3.4e-103 344.5 0.7 2.0 1 1 1 2 2 2 2 Mitochondrial protein Pet127 RPAP1_N PF08621.5 EPX71925.1 - 0.14 11.7 0.1 0.35 10.4 0.1 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal DNA_ligase_A_M PF01068.16 EPX71926.1 - 1.6e-49 168.0 0.0 3e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPX71926.1 - 2e-31 109.1 0.0 4.1e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPX71926.1 - 2.5e-12 47.0 0.0 5.6e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EPX71926.1 - 2.3e-08 34.0 0.1 0.0022 18.0 0.0 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 EPX71926.1 - 1.8e-05 24.4 4.1 3.2e-05 23.6 0.3 2.8 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain PTCB-BRCT PF12738.2 EPX71926.1 - 0.0074 16.1 0.0 0.44 10.4 0.0 2.6 2 0 0 2 2 2 1 twin BRCT domain UDG PF03167.14 EPX71927.1 - 2.4e-23 82.2 0.1 3.6e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Mob_Pre PF01076.14 EPX71927.1 - 5.1 6.6 7.2 31 4.1 0.0 2.6 2 1 0 2 2 2 0 Plasmid recombination enzyme Sec2p PF06428.6 EPX71928.1 - 1.5e-08 34.3 11.4 1.5e-08 34.3 7.9 1.9 1 1 0 1 1 1 1 GDP/GTP exchange factor Sec2p DUF3496 PF12001.3 EPX71928.1 - 0.016 15.4 6.1 0.016 15.4 4.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) Mu-like_Pro PF10123.4 EPX71928.1 - 0.04 13.3 3.1 0.046 13.1 2.1 1.0 1 0 0 1 1 1 0 Mu-like prophage I protein FTCD_C PF04961.7 EPX71928.1 - 0.045 13.1 3.0 0.06 12.7 2.1 1.2 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Alpha-2-MRAP_C PF06401.6 EPX71928.1 - 0.051 13.4 8.8 0.061 13.1 6.1 1.0 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Transposase_22 PF02994.9 EPX71928.1 - 0.067 11.6 12.3 0.085 11.3 8.5 1.1 1 0 0 1 1 1 0 L1 transposable element Synaptonemal_3 PF15191.1 EPX71928.1 - 0.082 12.6 4.8 0.12 12.1 2.6 1.9 1 1 1 2 2 2 0 Synaptonemal complex central element protein 3 ARA70 PF12489.3 EPX71928.1 - 0.11 12.4 7.4 0.13 12.2 4.8 1.4 1 1 0 1 1 1 0 Nuclear coactivator APG6 PF04111.7 EPX71928.1 - 0.13 11.3 11.3 0.14 11.1 7.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EPX71928.1 - 0.14 11.6 12.0 0.2 11.2 8.3 1.3 1 0 0 1 1 1 0 IncA protein DUF733 PF05306.6 EPX71928.1 - 0.15 12.3 15.2 0.33 11.2 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF733) Metal_resist PF13801.1 EPX71928.1 - 0.39 10.7 5.1 0.51 10.3 3.5 1.1 1 0 0 1 1 1 0 Heavy-metal resistance DUF1266 PF06889.6 EPX71928.1 - 0.42 10.4 2.7 0.61 9.8 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DivIVA PF05103.8 EPX71928.1 - 0.65 10.0 14.4 0.83 9.7 9.7 1.3 1 1 0 1 1 1 0 DivIVA protein Atg14 PF10186.4 EPX71928.1 - 1 8.2 12.9 1.2 8.0 9.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 KfrA_N PF11740.3 EPX71928.1 - 1.1 9.7 10.3 2.3 8.6 6.9 1.6 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term DUF4407 PF14362.1 EPX71928.1 - 1.6 7.6 4.7 2 7.3 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sin3_corepress PF08295.7 EPX71928.1 - 1.8 8.3 9.2 5.3 6.8 3.0 2.1 1 1 1 2 2 2 0 Sin3 family co-repressor Orbi_VP5 PF00901.12 EPX71928.1 - 2.9 6.0 11.5 3.6 5.6 8.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Phage_GP20 PF06810.6 EPX71928.1 - 3 7.2 13.9 1.1 8.7 7.8 1.6 2 1 0 2 2 2 0 Phage minor structural protein GP20 OmpH PF03938.9 EPX71928.1 - 4.1 7.3 15.6 5.8 6.8 10.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 EPX71928.1 - 4.3 5.0 9.4 4.9 4.8 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family T2SF PF00482.18 EPX71928.1 - 4.7 7.1 5.8 7.2 6.5 4.0 1.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F EssA PF10661.4 EPX71928.1 - 7.9 6.1 13.0 8.6 6.0 6.9 2.4 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA UCH PF00443.24 EPX71928.1 - 8.8 5.3 9.4 13 4.7 6.5 1.4 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase AAA_23 PF13476.1 EPX71928.1 - 9.6 6.4 8.4 15 5.8 5.8 1.3 1 0 0 1 1 1 0 AAA domain S1 PF00575.18 EPX71929.1 - 3.1e-70 232.2 35.8 5.1e-13 48.9 0.6 11.9 12 0 0 12 12 12 11 S1 RNA binding domain Suf PF05843.9 EPX71929.1 - 2e-10 40.8 0.2 1.8e-08 34.5 0.1 4.6 3 2 2 5 5 5 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EPX71929.1 - 2.2e-08 34.3 0.0 0.008 16.4 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPX71929.1 - 1.3e-06 28.5 0.0 0.32 11.7 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPX71929.1 - 2.3e-05 24.9 0.0 0.079 13.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPX71929.1 - 0.011 16.1 0.3 0.79 10.3 0.0 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.1 EPX71929.1 - 0.015 14.3 0.2 1.2 8.1 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Ribosomal_L1 PF00687.16 EPX71930.1 - 4.1e-50 170.1 0.7 4.8e-50 169.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pmp3 PF01679.12 EPX71931.1 - 7e-16 57.6 8.1 9e-16 57.3 5.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator IncA PF04156.9 EPX71931.1 - 0.051 13.1 0.1 0.059 12.9 0.1 1.1 1 0 0 1 1 1 0 IncA protein MS_channel PF00924.13 EPX71933.1 - 4.7e-20 71.8 1.2 1e-19 70.7 0.9 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel GST_N_3 PF13417.1 EPX71934.1 - 1.9e-15 56.8 0.0 3.3e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPX71934.1 - 4.2e-12 45.8 0.0 6.8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPX71934.1 - 7.6e-10 38.6 0.1 1.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EPX71934.1 - 1.3e-09 38.4 0.0 2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPX71934.1 - 8.8e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPX71934.1 - 2.5e-05 24.0 0.0 8.7e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EPX71934.1 - 0.0021 18.0 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Tub_2 PF04525.7 EPX71934.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Tubby C 2 Bac_rhodopsin PF01036.13 EPX71935.1 - 7.5e-29 100.6 26.4 1e-28 100.1 18.3 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein SAP PF02037.22 EPX71936.1 - 2.8e-12 45.7 2.4 4.5e-12 45.1 0.6 2.0 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 EPX71936.1 - 0.0013 18.2 0.2 0.0026 17.2 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain PA26 PF04636.8 EPX71936.1 - 5.1 5.6 6.0 7.4 5.1 4.2 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Ribosomal_L11_N PF03946.9 EPX71937.1 - 6.6e-17 60.7 0.2 1e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EPX71937.1 - 4e-11 42.8 0.1 7.8e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Metallophos PF00149.23 EPX71938.1 - 5e-44 150.0 0.2 6.1e-44 149.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sec23_trunk PF04811.10 EPX71940.1 - 9.2e-81 270.7 0.0 1.4e-80 270.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPX71940.1 - 2.9e-31 106.9 0.1 7.3e-31 105.6 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPX71940.1 - 5.7e-31 106.8 0.1 1.1e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EPX71940.1 - 1.7e-15 56.2 5.4 3.1e-15 55.4 3.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EPX71940.1 - 1.7e-11 43.6 0.0 7.1e-11 41.6 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat Exo_endo_phos PF03372.18 EPX71942.1 - 5.6e-22 78.8 0.0 1e-21 77.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EPX71942.1 - 3.2e-16 58.5 1.2 8.5e-09 34.8 0.5 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPX71942.1 - 1.8e-08 34.0 9.9 1.3e-05 24.8 1.2 2.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EPX71942.1 - 5.8e-07 28.6 2.8 0.34 11.0 0.0 5.4 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EPX71942.1 - 0.003 17.4 0.4 8.4 7.0 0.1 4.5 4 0 0 4 4 4 1 Leucine rich repeat WD40 PF00400.27 EPX71943.1 - 2.8e-60 198.1 15.5 5.2e-11 41.9 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EPX71943.1 - 5.2e-45 153.0 1.9 7.9e-45 152.4 1.3 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EPX71943.1 - 7.2e-06 25.5 0.1 2.4e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 LisH Nup160 PF11715.3 EPX71943.1 - 0.005 15.0 2.8 0.31 9.1 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Peptidase_C50 PF03568.12 EPX71944.1 - 3.7e-115 384.6 0.0 6.3e-115 383.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 TPR_2 PF07719.12 EPX71944.1 - 0.0034 17.1 0.3 9.1 6.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPX71944.1 - 0.026 14.8 0.1 11 6.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPX71944.1 - 0.063 13.2 2.8 32 4.5 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EPX71945.1 - 3.3e-27 95.8 0.0 4.3e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPX71945.1 - 7.9e-21 74.3 0.0 2.6e-20 72.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPX71945.1 - 1.5e-16 60.0 0.0 3.7e-16 58.7 0.0 1.6 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EPX71945.1 - 1.1e-12 48.0 0.2 8e-11 41.9 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EPX71945.1 - 0.00011 21.6 0.0 0.97 8.8 0.1 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EPX71945.1 - 0.00065 19.2 0.0 0.00081 18.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 EPX71945.1 - 0.0063 15.7 0.1 3.2 6.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EPX71945.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EPX71945.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.8 EPX71945.1 - 0.14 11.7 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Cir_N PF10197.4 EPX71946.1 - 0.61 10.1 0.1 0.61 10.1 0.0 3.5 3 1 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR SMC_N PF02463.14 EPX71947.1 - 9.6e-27 93.6 0.0 2.6e-26 92.2 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPX71947.1 - 1.4e-07 32.0 31.2 1.4e-07 32.0 21.6 5.7 3 2 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EPX71947.1 - 0.001 18.5 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.8 EPX71947.1 - 0.014 15.4 0.0 0.047 13.6 0.0 2.0 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EPX71947.1 - 0.033 14.1 0.3 0.033 14.1 0.2 3.6 4 1 0 4 4 4 0 AAA domain Halo_GVPC PF05465.8 EPX71947.1 - 0.11 12.4 0.5 21 5.1 0.0 3.6 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat ABC_tran PF00005.22 EPX71947.1 - 0.56 10.4 0.0 0.56 10.4 0.0 5.3 3 2 0 3 3 3 0 ABC transporter Ribosomal_L18e PF00828.14 EPX71948.1 - 8.5e-35 119.9 0.1 1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Lyase_8_N PF08124.6 EPX71948.1 - 0.087 11.6 0.0 0.095 11.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Rpr2 PF04032.11 EPX71949.1 - 1.4e-12 47.2 0.4 2.7e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_3 PF13878.1 EPX71949.1 - 0.11 12.1 0.1 0.92 9.1 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF155 PF02582.9 EPX71950.1 - 1.2e-53 181.5 1.4 1.6e-53 181.1 0.9 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Filament PF00038.16 EPX71951.1 - 0.003 17.0 1.4 0.0039 16.7 1.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein Tho2 PF11262.3 EPX71951.1 - 0.022 13.8 4.1 0.025 13.6 2.8 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ATG16 PF08614.6 EPX71951.1 - 0.041 13.7 1.2 0.044 13.5 0.8 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) YscO PF07321.7 EPX71951.1 - 0.043 13.6 1.5 0.053 13.3 1.1 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO Snapin_Pallidin PF14712.1 EPX71951.1 - 0.044 14.0 4.6 0.15 12.4 0.2 2.4 1 1 2 3 3 3 0 Snapin/Pallidin DUF4200 PF13863.1 EPX71951.1 - 0.067 13.1 3.5 0.08 12.8 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Kinesin-related PF06548.6 EPX71951.1 - 0.1 11.1 1.7 0.11 11.0 1.2 1.0 1 0 0 1 1 1 0 Kinesin-related Tup_N PF08581.5 EPX71951.1 - 0.48 10.6 5.4 1.1 9.4 3.6 1.7 1 1 0 1 1 1 0 Tup N-terminal Neurochondrin PF05536.6 EPX71952.1 - 1.5e-90 304.0 4.1 2e-90 303.6 2.8 1.1 1 0 0 1 1 1 1 Neurochondrin Rotamase PF00639.16 EPX71953.1 - 4.3e-24 85.0 0.0 5.7e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EPX71953.1 - 1.5e-19 70.4 0.0 1.7e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EPX71953.1 - 1.2e-07 31.4 1.5 1.9e-07 30.8 0.0 2.0 2 1 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 EPX71953.1 - 2.8e-07 31.1 0.0 4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain RNase_P_pop3 PF08228.6 EPX71955.1 - 3.4e-19 69.2 0.1 4e-19 68.9 0.1 1.0 1 0 0 1 1 1 1 RNase P subunit Pop3 PseudoU_synth_1 PF01416.15 EPX71956.1 - 2e-21 76.3 0.3 7.1e-10 39.2 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase RRM_1 PF00076.17 EPX71957.1 - 5.4e-14 51.5 0.0 5.2e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX71957.1 - 3.9e-05 23.5 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX71957.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EPX71958.1 - 2.3e-17 62.1 6.5 0.00018 21.2 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EPX71958.1 - 9.5e-06 25.3 0.0 0.00035 20.3 0.0 2.6 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 EPX71958.1 - 0.00012 20.9 1.8 0.11 11.2 0.0 3.1 1 1 2 3 3 3 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 EPX71958.1 - 0.0039 16.0 0.0 0.0058 15.4 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region PQQ PF01011.16 EPX71958.1 - 0.024 14.1 0.0 0.071 12.6 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat RNB PF00773.14 EPX71959.1 - 1.1e-51 176.0 0.0 1.5e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 RNB domain CBFD_NFYB_HMF PF00808.18 EPX71960.1 - 3.4e-13 49.4 0.2 4e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPX71960.1 - 5.8e-07 29.5 0.1 7.1e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_30kDa PF03540.8 EPX71960.1 - 0.0041 16.9 0.3 0.0088 15.8 0.2 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TFIID-18kDa PF02269.11 EPX71960.1 - 0.0093 15.7 0.4 0.015 15.1 0.3 1.4 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.8 EPX71960.1 - 0.031 14.5 0.7 0.04 14.2 0.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-S PF15630.1 EPX71960.1 - 0.097 12.8 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Kinetochore component CENP-S Glucosamine_iso PF01182.15 EPX71961.1 - 4.9e-60 202.6 0.0 5.9e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Pkinase PF00069.20 EPX71962.1 - 1.7e-75 253.5 0.0 2e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71962.1 - 7.9e-36 123.4 0.0 9.7e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX71962.1 - 0.00078 19.2 0.0 0.14 11.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EPX71962.1 - 0.025 13.5 0.0 0.044 12.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EPX71962.1 - 0.16 11.0 0.0 0.42 9.6 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_1 PF00583.19 EPX71963.1 - 1.1e-12 47.7 0.0 1.6e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPX71963.1 - 1.7e-05 24.8 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPX71963.1 - 0.00015 21.4 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPX71963.1 - 0.00047 20.2 0.0 0.00067 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPX71963.1 - 0.0042 16.9 0.1 0.0065 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPX71963.1 - 0.079 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L11_N PF03946.9 EPX71964.1 - 6.6e-17 60.7 0.2 1e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EPX71964.1 - 4e-11 42.8 0.1 7.8e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain TPR_11 PF13414.1 EPX71965.1 - 1.5e-21 75.8 18.4 0.00011 21.7 0.3 8.7 6 2 3 9 9 9 4 TPR repeat TPR_2 PF07719.12 EPX71965.1 - 3.6e-14 51.4 17.4 0.0048 16.7 0.8 10.3 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPX71965.1 - 8.9e-14 50.1 12.2 4.5e-05 22.9 0.1 7.9 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPX71965.1 - 6.3e-13 47.7 16.0 0.00011 21.5 0.5 7.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPX71965.1 - 3.7e-12 46.5 6.1 0.047 14.3 0.0 7.8 7 1 2 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPX71965.1 - 4.2e-12 45.5 6.9 0.029 14.9 0.0 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPX71965.1 - 1.1e-11 44.9 7.2 0.0026 18.0 0.1 8.6 8 2 1 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPX71965.1 - 1.8e-08 34.2 26.0 0.006 16.4 0.3 7.9 8 1 2 10 10 10 5 Tetratricopeptide repeat TPR_6 PF13174.1 EPX71965.1 - 7.5e-07 29.2 3.3 0.025 15.0 0.1 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPX71965.1 - 3.2e-05 23.1 5.3 0.0035 16.4 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPX71965.1 - 0.00015 21.5 8.1 0.19 11.7 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPX71965.1 - 0.00062 19.5 8.3 0.0052 16.6 0.2 5.3 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPX71965.1 - 0.0023 17.5 9.7 0.27 11.1 0.1 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPX71965.1 - 0.17 12.1 16.2 14 6.2 0.0 7.8 10 0 0 10 10 10 0 Tetratricopeptide repeat Ribosomal_L2_C PF03947.13 EPX71966.1 - 6.3e-49 165.0 0.2 1e-48 164.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPX71966.1 - 3.5e-28 97.3 0.2 3.5e-27 94.1 0.0 2.4 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Toxin_39 PF15500.1 EPX71966.1 - 0.031 14.3 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNase-like toxin DUF2414 PF10309.4 EPX71967.1 - 2.1e-19 68.9 0.0 3.2e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DUF1546 PF07571.8 EPX71969.1 - 6.2e-35 119.1 0.0 1.3e-34 118.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EPX71969.1 - 1.6e-28 98.4 0.3 2.9e-28 97.5 0.2 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EPX71969.1 - 0.0062 16.6 0.3 0.016 15.3 0.1 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 HEAT_EZ PF13513.1 EPX71969.1 - 0.012 16.1 0.7 3.3 8.3 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat CBFD_NFYB_HMF PF00808.18 EPX71969.1 - 0.019 14.9 0.2 0.064 13.3 0.1 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Vps5 PF09325.5 EPX71970.1 - 4.6e-64 215.9 11.7 6.5e-64 215.4 8.1 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EPX71970.1 - 3e-24 84.9 0.4 7.6e-24 83.6 0.0 1.9 2 0 0 2 2 2 1 PX domain DUF2524 PF10732.4 EPX71970.1 - 0.13 12.4 2.7 1.5 8.9 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) BAR PF03114.13 EPX71970.1 - 0.28 10.6 8.1 0.13 11.7 3.7 1.7 2 0 0 2 2 2 0 BAR domain FGGY_C PF02782.11 EPX71971.1 - 9.3e-28 97.1 0.0 1.8e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EPX71971.1 - 2.7e-17 62.9 0.0 7.3e-15 54.9 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain ABC2_membrane PF01061.19 EPX71972.1 - 4.3e-81 271.0 59.5 2.9e-43 147.4 14.5 3.0 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EPX71972.1 - 5.8e-35 119.0 13.0 4.4e-29 100.1 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 EPX71972.1 - 6e-35 120.5 0.0 2.1e-17 63.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 EPX71972.1 - 3.8e-11 42.9 0.0 1.1e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EPX71972.1 - 9.9e-07 28.3 0.0 0.00015 21.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EPX71972.1 - 2.2e-06 26.9 0.0 7.9e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPX71972.1 - 2.2e-05 24.5 0.6 0.0006 19.8 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EPX71972.1 - 0.00021 20.4 0.0 0.42 9.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.1 EPX71972.1 - 0.0004 19.8 0.1 0.038 13.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain UPF0079 PF02367.12 EPX71972.1 - 0.0013 18.3 0.2 0.066 12.8 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 EPX71972.1 - 0.0014 18.6 0.0 0.97 9.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EPX71972.1 - 0.002 18.2 0.1 0.053 13.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EPX71972.1 - 0.0021 17.1 20.9 0.0021 17.1 14.5 4.3 3 2 0 3 3 2 1 ABC-2 family transporter protein Miro PF08477.8 EPX71972.1 - 0.003 18.0 0.0 4.4 7.8 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 EPX71972.1 - 0.0045 17.2 0.6 0.12 12.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EPX71972.1 - 0.0057 16.3 0.4 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EPX71972.1 - 0.0078 15.8 0.4 0.15 11.7 0.0 2.6 3 0 0 3 3 2 1 NACHT domain AAA_33 PF13671.1 EPX71972.1 - 0.009 15.8 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EPX71972.1 - 0.0091 15.2 0.0 0.27 10.4 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EPX71972.1 - 0.014 14.8 0.2 3 7.1 0.1 3.3 3 0 0 3 3 3 0 AAA-like domain cobW PF02492.14 EPX71972.1 - 0.016 14.6 0.1 0.043 13.2 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EPX71972.1 - 0.034 13.7 0.1 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EPX71972.1 - 0.048 14.4 2.9 0.88 10.3 0.0 3.5 4 0 0 4 4 2 0 AAA domain AAA PF00004.24 EPX71972.1 - 0.079 13.1 0.0 4.8 7.3 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EPX71972.1 - 0.087 12.7 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EPX71972.1 - 0.1 12.0 0.1 1.6 8.2 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pex14_N PF04695.8 EPX71972.1 - 0.79 9.7 7.0 24 4.9 2.5 4.1 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 EPX71973.1 - 9.6e-48 162.5 0.0 1.3e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71973.1 - 5.9e-32 110.7 0.0 8.2e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EPX71973.1 - 0.32 9.7 0.0 0.47 9.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_S18 PF01084.15 EPX71974.1 - 4.5e-17 61.6 0.0 7.6e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Phos_pyr_kin PF08543.7 EPX71975.1 - 7.2e-58 195.6 0.0 9.1e-58 195.3 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.10 EPX71975.1 - 0.0091 15.1 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Diphtheria_T PF02764.9 EPX71975.1 - 0.03 14.0 0.0 0.085 12.6 0.0 1.7 1 1 1 2 2 2 0 Diphtheria toxin, T domain PXA PF02194.10 EPX71975.1 - 0.052 13.1 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 PXA domain eRF1_1 PF03463.10 EPX71976.1 - 4.1e-39 133.1 0.1 6.9e-39 132.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EPX71976.1 - 2.1e-31 109.0 0.2 3.2e-31 108.4 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EPX71976.1 - 4.5e-25 88.1 0.0 1e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 DUF1938 PF09153.5 EPX71976.1 - 0.0084 15.9 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1938) Ran_BP1 PF00638.13 EPX71977.1 - 1.4e-19 70.3 0.0 2.8e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 EPX71977.1 - 1.6e-12 47.5 0.6 1.6e-12 47.5 0.4 4.2 5 1 1 6 6 6 1 NUP50 (Nucleoporin 50 kDa) tRNA-synt_1 PF00133.17 EPX71978.1 - 5.3e-156 520.1 0.0 7.2e-156 519.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EPX71978.1 - 7.9e-25 87.3 0.0 2.2e-17 62.7 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EPX71978.1 - 3.5e-22 78.7 0.3 6.7e-22 77.8 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 EPX71978.1 - 0.0049 16.4 4.6 0.035 13.7 3.7 2.0 1 1 1 2 2 2 2 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 EPX71978.1 - 0.023 13.7 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain RNA_bind PF08675.6 EPX71979.1 - 0.0017 18.2 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 RNA binding domain RRM_5 PF13893.1 EPX71979.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EPX71980.1 - 4.5e-30 102.4 17.4 6.6e-10 38.4 0.5 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EPX71980.1 - 1.6e-07 31.2 0.2 1.7e-05 24.6 0.1 2.8 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EPX71980.1 - 0.00025 19.0 0.5 0.00093 17.1 0.0 2.0 3 0 0 3 3 3 1 IKI3 family Cytochrom_D1 PF02239.11 EPX71980.1 - 0.00092 17.6 0.0 0.019 13.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EPX71980.1 - 0.0026 16.5 1.1 0.88 8.2 0.2 2.9 2 1 1 3 3 3 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 EPX71980.1 - 0.052 12.3 0.0 0.34 9.6 0.0 1.9 1 1 0 2 2 2 0 Coatomer WD associated region Pkinase PF00069.20 EPX71981.1 - 3e-74 249.4 0.0 3.9e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71981.1 - 1.3e-36 125.9 0.0 1.8e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EPX71981.1 - 6.6e-14 51.7 0.2 1.3e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EPX71981.1 - 5.7e-11 41.9 0.0 4.4e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EPX71981.1 - 2.1e-05 23.9 0.1 3.8e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EPX71981.1 - 8.2e-05 21.7 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX71981.1 - 0.0014 18.3 0.0 0.7 9.5 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EPX71981.1 - 0.02 13.8 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase DUF3954 PF13128.1 EPX71981.1 - 0.13 11.7 0.0 0.33 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) CoaE PF01121.15 EPX71982.1 - 1.2e-59 200.7 0.0 1.4e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EPX71982.1 - 1.3e-06 29.1 0.1 3.8e-06 27.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPX71982.1 - 0.00042 20.6 0.1 0.0023 18.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPX71982.1 - 0.00049 19.9 0.1 0.0024 17.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain GspL_C PF12693.2 EPX71982.1 - 0.01 15.6 0.3 0.016 15.0 0.2 1.3 1 0 0 1 1 1 0 GspL periplasmic domain AAA_22 PF13401.1 EPX71982.1 - 0.038 14.1 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 EPX71982.1 - 0.055 13.3 0.0 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase PRK PF00485.13 EPX71982.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Npa1 PF11707.3 EPX71983.1 - 5.8e-63 212.8 2.4 5.8e-63 212.8 1.7 2.8 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 EPX71983.1 - 0.075 13.2 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Creb binding UMP1 PF05348.6 EPX71984.1 - 8.1e-33 113.1 0.1 9.6e-33 112.9 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DDHD PF02862.12 EPX71986.1 - 1.2e-41 143.0 3.4 2.6e-40 138.6 1.1 2.6 2 1 0 2 2 2 1 DDHD domain Abhydrolase_5 PF12695.2 EPX71986.1 - 0.025 14.3 0.0 0.062 13.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family XAP5 PF04921.9 EPX71987.1 - 2.4e-58 197.5 6.1 5.6e-58 196.3 4.2 1.7 1 1 0 1 1 1 1 XAP5, circadian clock regulator Rab5ip PF07019.7 EPX71988.1 - 3.6e-17 62.2 9.0 4.4e-17 61.9 6.3 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Pkinase PF00069.20 EPX71989.1 - 1e-57 195.2 0.0 1.9e-57 194.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX71989.1 - 5.7e-20 71.4 0.0 8.7e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX71989.1 - 0.0017 18.1 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPX71989.1 - 0.15 10.9 0.0 0.3 9.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Radical_SAM PF04055.16 EPX71990.1 - 7.6e-27 94.5 0.0 4.3e-26 92.0 0.0 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.7 EPX71990.1 - 1.4e-23 82.7 0.0 5.2e-23 80.9 0.0 2.1 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EPX71990.1 - 2.1e-14 53.6 0.0 4.6e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin HAD_2 PF13419.1 EPX71991.1 - 6.2e-20 72.1 0.0 7.4e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPX71991.1 - 2.5e-08 34.5 0.0 7.6e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EPX71991.1 - 9.7e-06 25.4 0.0 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPX71991.1 - 0.00015 21.4 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like NT5C PF06941.7 EPX71991.1 - 0.0015 18.0 0.0 0.0038 16.7 0.0 1.6 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Transaldolase PF00923.14 EPX71992.1 - 6e-98 327.5 0.4 6.9e-98 327.3 0.3 1.0 1 0 0 1 1 1 1 Transaldolase Metallophos PF00149.23 EPX71993.1 - 3.3e-16 59.2 0.0 5.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPX71993.1 - 3.4e-05 23.7 0.0 6e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RNA_pol_Rpb6 PF01192.17 EPX71994.1 - 2.5e-24 84.7 0.2 3.6e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Cation_efflux PF01545.16 EPX71995.1 - 1.4e-41 142.4 3.8 1.7e-41 142.1 2.7 1.1 1 0 0 1 1 1 1 Cation efflux family Spc7 PF08317.6 EPX71996.1 - 5.5e-71 238.8 22.5 5.5e-71 238.8 15.6 2.0 1 1 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EPX71996.1 - 4.9e-06 26.0 0.1 1.3e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 Spc7_C2 E1-E2_ATPase PF00122.15 EPX71997.1 - 2.9e-63 212.9 4.5 7.9e-63 211.5 3.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EPX71997.1 - 1.2e-21 78.1 0.0 2.4e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPX71997.1 - 7.5e-13 47.7 0.1 2e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EPX71997.1 - 5.2e-11 43.0 0.0 1.3e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPX71997.1 - 0.0015 18.1 0.1 0.0041 16.7 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPX71997.1 - 0.0066 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit CENP-T PF15511.1 EPX71997.1 - 2.4 7.2 25.0 4.9 6.2 17.3 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SPT2 PF08243.6 EPX71998.1 - 1.2e-25 90.0 14.2 1.2e-25 90.0 9.8 3.1 2 1 1 3 3 3 1 SPT2 chromatin protein Ribosomal_S19 PF00203.16 EPX71999.1 - 4.8e-30 103.0 0.0 6.8e-30 102.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FTA4 PF13093.1 EPX72000.1 - 1.5e-26 93.1 14.4 1.9e-26 92.8 10.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Ipi1_N PF12333.3 EPX72002.1 - 3.9e-25 87.7 0.2 4.8e-24 84.2 0.1 2.8 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation GATA PF00320.22 EPX72004.1 - 2.5e-29 100.3 16.3 6e-15 54.3 2.2 2.8 2 0 0 2 2 2 2 GATA zinc finger eIF-5_eIF-2B PF01873.12 EPX72004.1 - 9.7e-05 22.0 4.6 0.0076 15.9 0.5 2.2 2 0 0 2 2 2 2 Domain found in IF2B/IF5 ArfGap PF01412.13 EPX72004.1 - 0.00059 19.6 8.8 0.013 15.3 1.3 2.3 1 1 1 2 2 2 2 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.7 EPX72004.1 - 0.0012 18.1 1.5 0.6 9.4 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.2 EPX72004.1 - 0.034 13.9 8.3 0.37 10.6 0.5 2.6 1 1 1 2 2 2 0 Double zinc ribbon zf-CHY PF05495.7 EPX72004.1 - 0.16 12.1 4.8 5.5 7.2 0.4 2.4 2 0 0 2 2 2 0 CHY zinc finger FYVE PF01363.16 EPX72004.1 - 0.18 11.7 5.3 0.67 9.8 3.7 2.0 1 0 0 1 1 1 0 FYVE zinc finger Elf1 PF05129.8 EPX72004.1 - 0.48 10.1 5.8 0.12 12.1 0.4 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like NMD3 PF04981.8 EPX72004.1 - 0.63 9.1 6.2 8.6 5.3 0.5 2.1 1 1 1 2 2 2 0 NMD3 family RRN7 PF11781.3 EPX72004.1 - 4.6 6.8 8.4 0.17 11.4 0.2 2.5 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 OrfB_Zn_ribbon PF07282.6 EPX72004.1 - 8.3 6.1 9.8 12 5.6 1.1 2.6 1 1 1 2 2 2 0 Putative transposase DNA-binding domain DUF2296 PF10058.4 EPX72004.1 - 8.8 6.1 9.2 6 6.7 0.6 3.0 2 1 1 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Epimerase PF01370.16 EPX72005.1 - 1.2e-19 70.7 0.2 6.5e-19 68.2 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPX72005.1 - 4.5e-15 55.1 0.1 9.3e-15 54.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPX72005.1 - 5e-12 45.2 0.0 3.3e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EPX72005.1 - 1.9e-10 41.0 0.0 4.6e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPX72005.1 - 7.7e-06 25.9 0.2 0.00011 22.1 0.0 2.6 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EPX72005.1 - 8e-06 25.2 0.1 0.00031 20.0 0.1 2.3 2 1 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EPX72005.1 - 8e-05 21.6 0.1 0.00014 20.8 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EPX72005.1 - 0.0043 16.7 0.0 0.016 14.8 0.0 1.9 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EPX72005.1 - 0.084 12.7 0.1 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RWD PF05773.17 EPX72006.1 - 4.8e-19 68.3 1.5 4.8e-19 68.3 1.0 2.0 2 1 0 2 2 2 1 RWD domain DUF445 PF04286.7 EPX72006.1 - 0.00027 20.5 2.1 0.0004 20.0 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) IncFII_repA PF02387.10 EPX72006.1 - 0.019 14.1 3.9 0.025 13.7 2.7 1.1 1 0 0 1 1 1 0 IncFII RepA protein family Ctr PF04145.10 EPX72009.1 - 1.8e-31 109.1 12.2 2.9e-31 108.4 8.4 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Ten1 PF12658.2 EPX72010.1 - 5.9e-12 45.4 0.1 7.6e-12 45.0 0.1 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EPX72010.1 - 0.0011 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.6 EPX72010.1 - 0.0015 18.3 0.0 0.0019 18.0 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 MRP-L20 PF12824.2 EPX72011.1 - 9.9e-25 87.4 1.9 1.2e-24 87.0 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Sugarporin_N PF11471.3 EPX72011.1 - 3.9 7.2 8.2 0.32 10.6 2.3 1.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Laminin_II PF06009.7 EPX72012.1 - 0.062 13.0 0.9 0.11 12.2 0.6 1.4 1 0 0 1 1 1 0 Laminin Domain II PEP-utilisers_N PF05524.8 EPX72012.1 - 0.094 12.5 0.2 0.14 11.9 0.1 1.3 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal PorB PF11565.3 EPX72012.1 - 0.14 12.3 0.4 0.2 11.8 0.3 1.3 1 1 0 1 1 1 0 Alpha helical Porin B DUF4473 PF14747.1 EPX72012.1 - 0.18 12.0 2.2 0.26 11.5 0.5 1.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4473) DUF883 PF05957.8 EPX72012.1 - 0.33 11.3 2.2 0.28 11.6 0.6 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1129 PF06570.6 EPX72012.1 - 0.37 10.0 1.9 0.3 10.3 0.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) YtxH PF12732.2 EPX72012.1 - 3.4 8.0 7.1 3.5 8.0 1.3 2.3 2 0 0 2 2 2 0 YtxH-like protein DUF89 PF01937.14 EPX72013.1 - 1.6e-118 395.5 0.0 1.9e-118 395.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 MEKHLA PF08670.6 EPX72013.1 - 0.081 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 MEKHLA domain Sugar_tr PF00083.19 EPX72014.1 - 8.5e-42 143.2 9.3 2.8e-39 134.9 6.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPX72014.1 - 3e-18 65.6 18.9 3.3e-14 52.3 7.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Complex1_LYR PF05347.10 EPX72015.1 - 1.5e-07 31.1 1.8 1.5e-07 31.1 1.3 2.9 4 0 0 4 4 4 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPX72015.1 - 1.5e-07 31.5 3.1 1.5e-07 31.5 2.2 2.7 2 1 0 2 2 2 1 Complex1_LYR-like Mhr1 PF12829.2 EPX72016.1 - 0.076 12.8 0.1 0.3 10.9 0.1 1.9 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination Pex14_N PF04695.8 EPX72016.1 - 1.6 8.7 11.6 0.037 14.0 1.0 2.4 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Alpha-amylase PF00128.19 EPX72017.1 - 2.9e-61 207.5 7.9 2.9e-61 207.5 5.5 1.8 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EPX72017.1 - 1.5e-12 47.4 0.1 1.3e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) GHL15 PF14885.1 EPX72017.1 - 0.01 16.0 0.2 0.061 13.5 0.1 2.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 DUF3395 PF11875.3 EPX72018.1 - 2.4e-31 108.3 2.4 2.4e-31 108.3 1.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EPX72018.1 - 7.7e-22 76.8 0.8 7.7e-22 76.8 0.5 1.8 2 0 0 2 2 2 1 DnaJ domain Mod_r PF07200.8 EPX72018.1 - 1.1 9.1 9.9 0.098 12.5 3.2 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Glyco_transf_5 PF08323.6 EPX72019.1 - 1.3e-16 60.8 0.1 2.5e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EPX72019.1 - 2.2e-08 33.7 0.0 4.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 TAP42 PF04177.7 EPX72020.1 - 3.1e-75 253.2 18.0 4.9e-75 252.6 12.5 1.3 1 1 0 1 1 1 1 TAP42-like family MCPVI PF02993.9 EPX72020.1 - 0.0062 16.7 2.2 0.0094 16.1 1.5 1.3 1 0 0 1 1 1 1 Minor capsid protein VI C-term_anchor PF13461.1 EPX72020.1 - 0.16 12.4 0.4 29 5.2 0.1 2.8 2 0 0 2 2 2 0 Cell-wall surface anchor repeat WD40 PF00400.27 EPX72021.1 - 3.9e-09 36.0 1.2 6.9e-05 22.5 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Thg1 PF04446.7 EPX72022.1 - 1.5e-46 157.3 0.1 2.3e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 EPX72022.1 - 3.1e-46 155.9 2.7 4.8e-46 155.3 1.9 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Pkinase PF00069.20 EPX72023.1 - 4e-58 196.5 0.0 6.9e-58 195.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72023.1 - 9.9e-42 142.7 0.0 1.5e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 EPX72023.1 - 1.8e-39 135.4 3.1 2.7e-39 134.8 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) APH PF01636.18 EPX72023.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EPX72023.1 - 0.06 12.3 0.1 3.3 6.5 0.0 2.9 3 0 0 3 3 3 0 Kinase-like DUF937 PF06078.6 EPX72023.1 - 0.09 13.0 0.4 8.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) CTP_transf_1 PF01148.15 EPX72024.1 - 1.5e-09 37.9 9.0 1.5e-09 37.9 6.2 3.1 1 1 2 3 3 3 1 Cytidylyltransferase family DUF2567 PF10821.3 EPX72024.1 - 0.014 14.9 0.2 0.11 11.9 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2567) Proteasome PF00227.21 EPX72025.1 - 1.2e-42 145.3 0.0 1.3e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DnaJ PF00226.26 EPX72026.1 - 1.9e-21 75.5 0.2 4.3e-21 74.4 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 EPX72026.1 - 0.015 15.3 0.2 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.1 EPX72026.1 - 0.058 13.0 3.0 0.1 12.2 2.1 1.3 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 EPX72026.1 - 2.1 7.9 7.2 4.5 6.8 4.5 1.8 1 1 1 2 2 2 0 YMGG-like Gly-zipper DUF3812 PF12757.2 EPX72027.1 - 1.6e-11 44.2 16.0 9.4e-11 41.7 11.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3812) Frag1 PF10277.4 EPX72028.1 - 4.5e-30 104.7 20.0 5.3e-30 104.4 13.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF754 PF05449.6 EPX72028.1 - 0.019 14.9 5.9 2.2 8.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF754) MARVEL PF01284.18 EPX72028.1 - 2.1 8.1 24.4 7.2 6.4 4.3 3.5 1 1 2 3 3 3 0 Membrane-associating domain Glycos_transf_4 PF00953.16 EPX72028.1 - 3.2 7.5 10.5 1.5 8.6 1.5 2.7 2 1 0 2 2 2 0 Glycosyl transferase family 4 NfeD PF01957.13 EPX72028.1 - 4.5 7.3 11.0 0.92 9.6 1.2 3.1 1 1 3 4 4 4 0 NfeD-like C-terminal, partner-binding WD40 PF00400.27 EPX72029.1 - 4e-83 270.6 22.4 5.7e-11 41.8 0.1 12.0 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.6 EPX72029.1 - 9.2e-42 142.0 0.0 1.4e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EPX72029.1 - 3e-06 25.6 8.4 0.16 10.1 0.0 5.4 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPX72029.1 - 6.1e-05 21.9 3.2 0.99 8.0 0.0 4.7 3 2 2 5 5 5 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EPX72029.1 - 0.0023 16.2 0.7 0.014 13.7 0.0 2.4 3 0 0 3 3 3 1 Cytochrome D1 heme domain Nbas_N PF15492.1 EPX72029.1 - 0.0063 15.6 0.0 0.057 12.5 0.0 2.5 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal DUF2009 PF09418.5 EPX72030.1 - 1.4e-193 643.8 0.3 1.6e-193 643.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) PXA PF02194.10 EPX72031.1 - 2.3e-37 128.3 0.3 2.3e-37 128.3 0.2 3.0 3 1 0 3 3 3 1 PXA domain PX PF00787.19 EPX72031.1 - 5.5e-21 74.4 0.3 5.5e-21 74.4 0.2 3.8 3 1 1 4 4 4 1 PX domain RGS PF00615.14 EPX72031.1 - 1.6e-16 60.4 0.5 1.6e-16 60.4 0.3 2.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Nexin_C PF08628.7 EPX72031.1 - 5.6e-05 23.1 0.2 0.00028 20.9 0.1 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal MRC1 PF09444.5 EPX72031.1 - 0.36 11.1 6.5 0.46 10.8 3.1 2.2 1 1 1 2 2 2 0 MRC1-like domain Spectrin PF00435.16 EPX72031.1 - 2.7 8.3 15.3 0.9 9.8 3.6 3.3 3 0 0 3 3 3 0 Spectrin repeat DUF342 PF03961.8 EPX72031.1 - 4.6 5.5 6.6 1.5 7.1 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) SlyX PF04102.7 EPX72031.1 - 8.5 6.8 10.1 14 6.1 1.4 4.2 4 1 0 4 4 4 0 SlyX Sre PF03125.13 EPX72032.1 - 0.0011 17.9 0.0 0.0012 17.8 0.0 1.0 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor DUF3169 PF11368.3 EPX72032.1 - 0.0028 16.9 0.1 0.0033 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) DUF3278 PF11683.3 EPX72032.1 - 0.022 14.7 0.1 0.028 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) Mem_trans PF03547.13 EPX72032.1 - 0.11 10.7 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF3671 PF12420.3 EPX72032.1 - 0.19 11.7 3.9 0.27 11.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF4234 PF14018.1 EPX72033.1 - 0.088 12.5 0.5 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) DIM1 PF02966.11 EPX72034.1 - 4.4e-68 226.8 0.5 5e-68 226.7 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EPX72034.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Glyco_transf_22 PF03901.12 EPX72035.1 - 2.9e-101 339.4 35.7 3.4e-101 339.2 24.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Polyketide_cyc PF03364.15 EPX72036.1 - 1.3e-24 86.6 0.0 1.5e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EPX72036.1 - 0.00019 21.6 0.0 0.00023 21.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PX PF00787.19 EPX72037.1 - 4.8e-19 68.2 0.0 1.5e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 PX domain DUF3944 PF13099.1 EPX72037.1 - 0.035 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) Tim17 PF02466.14 EPX72038.1 - 1.3e-27 96.3 3.6 1.6e-27 96.0 2.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cyt-b5 PF00173.23 EPX72039.1 - 5e-23 80.7 0.1 6.6e-23 80.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain L31 PF09784.4 EPX72040.1 - 1.6e-40 137.3 0.4 1.8e-40 137.1 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 UCH PF00443.24 EPX72041.1 - 1.4e-75 253.8 0.0 3.1e-75 252.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPX72041.1 - 3.3e-17 62.8 0.9 2.4e-08 33.8 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EPX72041.1 - 1.3e-14 54.4 1.5 2.8e-14 53.2 0.1 2.4 3 0 0 3 3 3 1 DUSP domain DUF1600 PF07667.6 EPX72041.1 - 0.012 15.7 0.6 0.04 13.9 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) DUF544 PF04424.8 EPX72041.1 - 0.048 13.4 0.5 12 5.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF544) LUC7 PF03194.10 EPX72042.1 - 3.7e-85 285.5 9.4 4.5e-85 285.2 6.5 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MAT1 PF06391.8 EPX72042.1 - 0.0038 16.8 2.8 0.0069 15.9 2.0 1.5 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 MCPsignal PF00015.16 EPX72042.1 - 0.059 12.8 0.5 0.087 12.3 0.4 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain UPF0242 PF06785.6 EPX72042.1 - 0.16 10.6 4.8 0.55 8.8 2.8 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) DUF4119 PF13494.1 EPX72042.1 - 0.34 10.9 3.2 3.2 7.8 1.4 2.4 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) DUF4200 PF13863.1 EPX72042.1 - 0.43 10.5 7.2 1.2 9.1 4.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) WEMBL PF05701.6 EPX72042.1 - 0.53 8.6 10.6 0.3 9.5 2.2 2.7 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Occludin_ELL PF07303.8 EPX72042.1 - 1.1 10.0 6.6 1.5 9.5 2.0 2.4 1 1 1 2 2 2 0 Occludin homology domain zf-C4H2 PF10146.4 EPX72042.1 - 4 7.4 12.4 4.2 7.3 7.8 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein CorA PF01544.13 EPX72042.1 - 4.8 6.1 6.5 5.8 5.8 4.0 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SNF5 PF04855.7 EPX72043.1 - 1.1e-63 214.9 0.3 7.3e-62 209.0 0.2 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EPX72043.1 - 3.4e-10 39.0 5.3 3.4e-10 39.0 3.7 2.8 2 0 0 2 2 2 1 GATA zinc finger DUF3752 PF12572.3 EPX72044.1 - 0.021 14.9 1.4 0.028 14.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Proteasom_Rpn13 PF04683.8 EPX72045.1 - 1.3e-27 95.6 0.1 2.7e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor MCM PF00493.18 EPX72046.1 - 4.1e-139 462.9 0.4 5.9e-139 462.4 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPX72046.1 - 9.7e-25 87.4 2.3 1.1e-23 83.9 0.1 3.5 3 1 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPX72046.1 - 6.4e-06 25.4 0.0 0.00054 19.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPX72046.1 - 5.2e-05 22.9 0.0 0.00017 21.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPX72046.1 - 0.00019 21.0 0.0 0.002 17.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Elf1 PF05129.8 EPX72046.1 - 0.036 13.7 0.8 0.079 12.6 0.5 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Sigma54_activat PF00158.21 EPX72046.1 - 0.076 12.4 0.5 5.7 6.3 0.0 3.4 4 0 0 4 4 4 0 Sigma-54 interaction domain HHH_5 PF14520.1 EPX72046.1 - 0.091 12.9 0.4 0.32 11.2 0.1 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain NAD_kinase PF01513.16 EPX72047.1 - 1.3e-50 171.7 0.0 1.6e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase ATP-synt_E_2 PF08112.6 EPX72048.1 - 0.12 12.4 3.3 0.15 12.1 1.4 1.9 2 0 0 2 2 2 0 ATP synthase epsilon subunit Mnd1 PF03962.10 EPX72048.1 - 0.18 11.4 5.8 0.21 11.2 4.0 1.1 1 0 0 1 1 1 0 Mnd1 family DUF972 PF06156.8 EPX72048.1 - 2.5 8.4 5.4 1.2 9.5 1.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Ribosomal_L50 PF10501.4 EPX72049.1 - 8.7e-05 22.4 0.0 0.00033 20.6 0.0 1.9 1 1 0 1 1 1 1 Ribosomal subunit 39S DUF2424 PF10340.4 EPX72049.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) zf-Tim10_DDP PF02953.10 EPX72050.1 - 1.2e-16 59.7 3.2 1.4e-16 59.4 2.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Anillin PF08174.6 EPX72050.1 - 0.034 14.2 0.2 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 Cell division protein anillin Pkinase PF00069.20 EPX72052.1 - 6.1e-68 228.7 0.0 8.4e-68 228.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72052.1 - 4.8e-30 104.5 0.0 7.6e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EPX72052.1 - 2.7e-09 37.3 0.7 7.2e-09 36.0 0.5 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPX72052.1 - 0.00054 18.9 0.0 0.00097 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 EPX72052.1 - 0.062 13.1 0.0 0.23 11.3 0.0 2.0 1 1 0 1 1 1 0 C2 domain Choline_kinase PF01633.15 EPX72052.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Myb_DNA-binding PF00249.26 EPX72053.1 - 6e-13 48.6 0.0 1.5e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EPX72053.1 - 4.6e-11 42.0 3.9 7.9e-11 41.3 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 EPX72053.1 - 7.1e-09 35.6 2.5 3.7e-07 30.1 0.0 3.3 3 1 0 3 3 3 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 EPX72053.1 - 1.2e-05 25.3 0.0 3.2e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Baculo_IE-1 PF05290.6 EPX72053.1 - 0.0023 17.6 1.9 0.0055 16.4 1.3 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Ribosomal_S17e PF00833.13 EPX72054.1 - 1.2e-61 205.9 1.5 1.3e-61 205.7 1.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 PdxJ PF03740.8 EPX72054.1 - 0.022 13.9 0.1 0.026 13.6 0.1 1.1 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ DIRP PF06584.8 EPX72054.1 - 0.046 13.5 0.2 0.072 12.9 0.1 1.4 1 1 0 1 1 1 0 DIRP AIG2 PF06094.7 EPX72054.1 - 0.091 13.2 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AIG2-like family Cryptochrome_C PF12546.3 EPX72054.1 - 0.099 13.3 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal AAA PF00004.24 EPX72055.1 - 2e-38 131.5 0.0 6.3e-38 129.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPX72055.1 - 1.8e-07 31.3 1.6 6.1e-05 23.1 0.3 3.4 2 1 0 3 3 2 1 AAA domain RuvB_N PF05496.7 EPX72055.1 - 3.4e-07 29.5 0.0 1e-06 28.0 0.0 1.8 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPX72055.1 - 6.3e-07 29.5 2.1 0.0006 19.8 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EPX72055.1 - 8.4e-07 28.7 0.2 4.3e-06 26.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EPX72055.1 - 2e-06 27.7 0.0 4.3e-06 26.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EPX72055.1 - 9.6e-06 26.4 0.0 3.7e-05 24.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EPX72055.1 - 0.00022 21.1 0.0 0.00063 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPX72055.1 - 0.00025 20.4 2.1 0.05 12.9 0.1 2.5 2 1 1 3 3 2 1 AAA domain IstB_IS21 PF01695.12 EPX72055.1 - 0.00026 20.4 0.0 0.00053 19.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EPX72055.1 - 0.0003 20.0 0.2 0.00076 18.6 0.1 1.7 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EPX72055.1 - 0.00056 19.9 0.0 0.0015 18.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EPX72055.1 - 0.00067 19.9 0.0 0.003 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPX72055.1 - 0.00071 18.7 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_2 PF07724.9 EPX72055.1 - 0.00076 19.4 0.0 0.0019 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EPX72055.1 - 0.00083 19.5 0.0 0.0018 18.3 0.0 1.7 2 0 0 2 2 1 1 RNA helicase Sigma54_activ_2 PF14532.1 EPX72055.1 - 0.0015 18.5 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.1 EPX72055.1 - 0.0016 18.0 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 EPX72055.1 - 0.0021 17.7 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein NACHT PF05729.7 EPX72055.1 - 0.0025 17.5 0.1 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.21 EPX72055.1 - 0.0045 16.4 0.0 0.016 14.7 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain DEAD PF00270.24 EPX72055.1 - 0.0046 16.4 0.1 0.16 11.4 0.0 2.7 4 0 0 4 4 3 1 DEAD/DEAH box helicase ATP-synt_ab PF00006.20 EPX72055.1 - 0.0048 16.4 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 EPX72055.1 - 0.005 15.5 0.0 0.0071 15.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EPX72055.1 - 0.0055 16.4 0.0 0.15 11.7 0.0 2.4 1 1 1 2 2 2 1 Archaeal ATPase Viral_helicase1 PF01443.13 EPX72055.1 - 0.0076 15.7 0.0 0.081 12.4 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 EPX72055.1 - 0.01 14.9 0.0 0.74 8.8 0.0 2.5 1 1 1 2 2 2 0 KaiC AAA_21 PF13304.1 EPX72055.1 - 0.015 15.2 0.9 4.7 7.0 0.3 2.4 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EPX72055.1 - 0.017 15.4 0.2 0.036 14.3 0.0 1.9 2 1 0 2 2 1 0 ABC transporter Guanylate_kin PF00625.16 EPX72055.1 - 0.02 14.3 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase AAA_19 PF13245.1 EPX72055.1 - 0.022 14.5 0.0 0.095 12.4 0.0 2.0 2 0 0 2 2 1 0 Part of AAA domain AAA_3 PF07726.6 EPX72055.1 - 0.026 14.1 0.0 0.1 12.2 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EPX72055.1 - 0.028 14.2 0.8 0.093 12.5 0.0 2.2 3 0 0 3 3 1 0 Shikimate kinase UPF0079 PF02367.12 EPX72055.1 - 0.033 13.8 0.1 0.46 10.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 EPX72055.1 - 0.037 13.6 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.12 EPX72055.1 - 0.048 12.5 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TIP49 PF06068.8 EPX72055.1 - 0.08 11.6 0.0 0.15 10.7 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus AAA_10 PF12846.2 EPX72055.1 - 0.092 12.1 0.2 0.83 9.0 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain NB-ARC PF00931.17 EPX72055.1 - 0.1 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF815 PF05673.8 EPX72055.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.1 EPX72055.1 - 0.12 11.9 0.1 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain THOC7 PF05615.8 EPX72056.1 - 3e-16 59.9 9.9 3e-16 59.9 6.8 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 TcdB_N PF12918.2 EPX72056.1 - 0.0026 17.7 1.2 0.0026 17.7 0.8 2.1 2 0 0 2 2 2 1 TcdB toxin N-terminal helical domain Ax_dynein_light PF10211.4 EPX72056.1 - 0.016 15.0 7.0 0.016 15.0 4.8 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Streptin-Immun PF11083.3 EPX72056.1 - 0.02 14.8 11.5 0.072 13.0 0.4 2.6 2 1 1 3 3 3 0 Lantibiotic streptin immunity protein Lebercilin PF15619.1 EPX72056.1 - 0.023 14.1 18.3 0.034 13.5 12.7 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Macoilin PF09726.4 EPX72056.1 - 0.036 12.3 12.0 0.049 11.9 8.3 1.3 1 0 0 1 1 1 0 Transmembrane protein ATG16 PF08614.6 EPX72056.1 - 0.14 11.9 18.6 0.3 10.8 5.0 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-Q PF13094.1 EPX72056.1 - 0.24 11.4 24.6 1.9 8.5 9.6 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 EPX72056.1 - 0.26 11.1 19.1 4.3 7.2 6.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FliJ PF02050.11 EPX72056.1 - 0.35 10.9 24.4 17 5.4 8.8 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein FUSC PF04632.7 EPX72056.1 - 0.67 8.3 2.8 0.78 8.0 1.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.4 EPX72056.1 - 0.72 9.7 22.5 0.64 9.8 2.4 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 EPX72056.1 - 0.98 7.7 11.2 1.2 7.4 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Asp-B-Hydro_N PF05279.6 EPX72056.1 - 1.2 8.9 12.2 1.6 8.5 8.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mnd1 PF03962.10 EPX72056.1 - 1.4 8.5 18.0 1.6 8.3 11.4 1.7 1 1 1 2 2 2 0 Mnd1 family Exonuc_VII_L PF02601.10 EPX72056.1 - 1.6 7.8 8.1 1.8 7.6 5.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TBPIP PF07106.8 EPX72056.1 - 2.5 7.6 18.5 5.5 6.5 12.4 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) XRCC4 PF06632.7 EPX72056.1 - 3.1 6.5 13.8 2.5 6.8 7.0 2.0 1 1 1 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DivIC PF04977.10 EPX72056.1 - 3.7 7.1 21.7 0.087 12.3 2.6 2.5 1 1 1 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.7 EPX72056.1 - 5.9 6.6 25.9 0.32 10.7 3.9 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EPX72056.1 - 7.8 5.4 22.4 14 4.6 15.5 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 CGI-121 PF08617.5 EPX72057.1 - 2.1e-44 151.0 0.9 2.4e-44 150.8 0.6 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF3568 PF12092.3 EPX72057.1 - 0.046 13.4 0.1 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) SH3_9 PF14604.1 EPX72058.1 - 4.5e-10 38.9 0.0 7.6e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPX72058.1 - 1.3e-08 34.0 0.5 3e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EPX72058.1 - 2.3e-06 26.9 0.0 4.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Imm28 PF15574.1 EPX72058.1 - 0.051 13.1 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 28 XLF PF09302.6 EPX72059.1 - 2.1e-19 69.9 2.3 2.6e-19 69.6 1.6 1.1 1 0 0 1 1 1 1 XLF (XRCC4-like factor) PIN_4 PF13638.1 EPX72060.1 - 2.5e-29 102.0 0.0 4.4e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 PIN domain EMP24_GP25L PF01105.19 EPX72062.1 - 5.2e-45 153.4 0.1 8.2e-45 152.7 0.1 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2462 PF09495.5 EPX72063.1 - 1.4e-13 51.3 10.5 1.7e-13 51.1 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) DUF2855 PF11017.3 EPX72063.1 - 0.18 10.9 1.4 0.21 10.7 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) TIM PF00121.13 EPX72065.1 - 4.6e-87 291.1 0.7 5.2e-87 290.9 0.5 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase RNA_pol_Rpb1_3 PF04983.13 EPX72065.1 - 0.034 13.8 0.2 0.1 12.3 0.1 1.7 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 3 DNA_pol_A PF00476.15 EPX72066.1 - 6.2e-90 301.5 0.0 9.9e-90 300.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EPX72066.1 - 0.00026 20.5 0.2 0.0043 16.5 0.1 2.4 1 1 0 1 1 1 1 3'-5' exonuclease PH PF00169.24 EPX72067.1 - 6.9e-21 74.4 2.5 2.3e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 PH domain PH_6 PF15406.1 EPX72067.1 - 0.0013 18.7 0.0 0.58 10.2 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 EPX72067.1 - 0.0017 18.5 6.1 1 9.6 0.4 3.5 2 2 1 3 3 3 2 Pleckstrin homology domain Mcp5_PH PF12814.2 EPX72067.1 - 0.035 14.0 1.3 0.22 11.4 0.1 2.4 2 1 1 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology NAC PF01849.13 EPX72067.1 - 0.16 11.5 0.3 0.32 10.5 0.2 1.4 1 0 0 1 1 1 0 NAC domain PP2C PF00481.16 EPX72068.1 - 6.2e-85 284.6 0.0 7.6e-85 284.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Recep_L_domain PF01030.19 EPX72069.1 - 1e-13 51.2 7.8 0.00011 22.1 0.2 5.4 1 1 5 6 6 6 4 Receptor L domain LRR_5 PF13306.1 EPX72069.1 - 0.2 11.3 3.9 0.19 11.4 0.3 2.5 1 1 2 3 3 3 0 Leucine rich repeats (6 copies) BTD PF09270.5 EPX72070.1 - 8.6e-40 136.0 0.1 1.4e-39 135.3 0.1 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 EPX72070.1 - 2.7e-26 92.7 0.1 6e-26 91.5 0.1 1.6 1 0 0 1 1 1 1 LAG1, DNA binding Chorismate_synt PF01264.16 EPX72071.1 - 6.7e-130 432.5 0.4 1.6e-129 431.3 0.3 1.5 1 1 0 1 1 1 1 Chorismate synthase Pkinase PF00069.20 EPX72072.1 - 3.1e-60 203.5 0.0 4.3e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72072.1 - 9.1e-33 113.4 0.0 1.3e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX72072.1 - 3.8e-09 35.9 0.0 5.4e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SET PF00856.23 EPX72073.1 - 8.7e-12 45.6 0.3 6.3e-08 33.0 0.2 2.1 1 1 1 2 2 2 2 SET domain DENN PF02141.16 EPX72074.1 - 1.3e-49 168.4 0.9 2.3e-49 167.6 0.7 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EPX72074.1 - 1.8e-15 56.6 0.2 5.2e-15 55.1 0.2 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EPX72074.1 - 1.7e-14 53.5 4.2 7.5e-14 51.5 2.9 2.2 1 0 0 1 1 1 1 dDENN domain DUF2093 PF09866.4 EPX72074.1 - 0.003 16.7 0.6 0.01 14.9 0.4 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2093) DUF2731 PF10806.3 EPX72074.1 - 0.033 14.4 0.1 0.098 12.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2731) SPA PF08616.5 EPX72074.1 - 0.11 12.2 0.3 0.26 10.9 0.2 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis NMD3 PF04981.8 EPX72074.1 - 0.14 11.2 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 NMD3 family DUF4142 PF13628.1 EPX72074.1 - 0.26 11.2 0.1 0.58 10.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) DUF3294 PF07957.6 EPX72075.1 - 2.7e-18 66.2 17.0 3.6e-18 65.8 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) UCR_14kD PF02271.11 EPX72076.1 - 5e-40 135.5 0.9 5.8e-40 135.2 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Ima1_N PF09779.4 EPX72077.1 - 6.4e-32 110.7 3.6 6.4e-32 110.7 2.5 2.8 2 1 0 2 2 2 1 Ima1 N-terminal domain zf-MIZ PF02891.15 EPX72077.1 - 0.032 13.7 1.4 0.093 12.2 1.0 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Sec23_Sec24 PF04810.10 EPX72077.1 - 0.042 13.4 5.5 0.036 13.6 1.8 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RING_3 PF14369.1 EPX72077.1 - 0.4 10.7 4.9 0.11 12.4 0.9 2.0 2 0 0 2 2 2 0 zinc-finger PHD PF00628.24 EPX72077.1 - 4.2 7.1 8.6 13 5.5 0.9 2.9 3 0 0 3 3 3 0 PHD-finger Yip1 PF04893.12 EPX72078.1 - 1.3e-09 37.7 13.3 2e-09 37.1 9.2 1.3 1 0 0 1 1 1 1 Yip1 domain Carb_kinase PF01256.12 EPX72079.1 - 8.1e-57 192.2 0.0 9.3e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EPX72079.1 - 0.00011 21.4 0.0 0.0005 19.3 0.0 1.8 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TFIID-18kDa PF02269.11 EPX72080.1 - 1.3e-37 127.5 2.2 1.5e-37 127.2 0.5 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit NUP PF06516.6 EPX72080.1 - 0.012 14.4 0.2 0.02 13.7 0.1 1.3 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) Metallopep PF12044.3 EPX72080.1 - 0.04 12.3 0.3 0.81 8.0 0.0 2.1 2 0 0 2 2 2 0 Putative peptidase family MFS_1 PF07690.11 EPX72081.1 - 1.4e-13 50.3 45.0 2.9e-12 45.9 30.4 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily SYS1 PF09801.4 EPX72081.1 - 2.5 8.0 9.9 3.7 7.5 4.6 2.8 1 1 1 2 2 2 0 Integral membrane protein S linking to the trans Golgi network Cupin_8 PF13621.1 EPX72082.1 - 1.1e-54 185.6 0.0 1.7e-54 184.9 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EPX72082.1 - 0.0004 19.7 0.0 0.0014 17.9 0.0 2.0 3 0 0 3 3 3 1 Cupin superfamily protein 2OG-FeII_Oxy_5 PF13759.1 EPX72082.1 - 0.047 13.9 0.3 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase JmjC PF02373.17 EPX72082.1 - 0.1 12.8 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 JmjC domain, hydroxylase Ribosomal_L6e PF01159.14 EPX72083.1 - 5.7e-36 123.0 0.0 7.6e-36 122.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.24 EPX72083.1 - 0.13 12.0 0.1 0.52 10.1 0.1 2.0 1 1 1 2 2 2 0 KOW motif AP_endonuc_2 PF01261.19 EPX72084.1 - 2.9e-27 95.3 0.1 4.4e-27 94.7 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel NAF PF03822.9 EPX72084.1 - 2.2 8.0 4.5 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 NAF domain JmjC PF02373.17 EPX72085.1 - 2.6e-08 34.0 0.2 3.4e-07 30.5 0.1 2.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase ArfGap PF01412.13 EPX72087.1 - 3.1e-37 126.9 1.3 5.7e-37 126.0 0.1 2.0 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf ELFV_dehydrog PF00208.16 EPX72089.1 - 2.6e-77 259.7 1.8 3.1e-77 259.4 1.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EPX72089.1 - 3.1e-47 159.4 0.0 8.6e-47 157.9 0.0 1.7 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EPX72089.1 - 0.12 12.6 0.1 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding LMBR1 PF04791.11 EPX72090.1 - 1.9e-78 264.1 33.8 6.1e-78 262.5 23.5 1.6 1 1 0 1 1 1 1 LMBR1-like membrane protein Sec5 PF15469.1 EPX72091.1 - 5.5e-21 75.1 2.8 5.5e-21 75.1 1.9 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec5 Histone PF00125.19 EPX72092.1 - 3.2e-23 81.6 0.3 4.4e-23 81.1 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPX72092.1 - 1.8e-06 27.8 0.1 3.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EPX72092.1 - 6.7e-05 23.0 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 EPX72093.1 - 7.8e-26 90.0 0.0 1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPX72093.1 - 1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GST_N_2 PF13409.1 EPX72094.1 - 3.4e-21 74.9 0.1 8.7e-21 73.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPX72094.1 - 1.2e-16 60.3 0.0 2.2e-15 56.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPX72094.1 - 1e-06 28.6 0.1 2.1e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPX72094.1 - 2.9e-06 27.6 0.0 6.5e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPX72094.1 - 0.0021 18.2 0.1 0.024 14.8 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FA_desaturase PF00487.19 EPX72095.1 - 6.3e-18 65.1 17.7 6.3e-18 65.1 12.2 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EPX72095.1 - 1.6e-10 40.6 0.0 4.4e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CRC_subunit PF08624.5 EPX72096.1 - 2.6e-57 192.6 0.0 4.8e-57 191.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit EF-1_beta_acid PF10587.4 EPX72096.1 - 0.14 12.2 4.5 0.43 10.7 3.1 1.8 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region DUF1077 PF06417.7 EPX72097.1 - 1.1e-46 157.3 2.8 1.4e-46 156.9 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TUDOR PF00567.19 EPX72098.1 - 0.00031 20.5 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.1 EPX72098.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.5 EPX72098.1 - 0.098 12.2 0.2 0.23 11.0 0.1 1.6 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain DUF883 PF05957.8 EPX72098.1 - 0.53 10.7 3.1 1.1 9.6 2.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Alpha-amylase PF00128.19 EPX72099.1 - 7e-23 81.5 14.3 2.4e-18 66.5 2.2 4.0 2 1 1 3 3 3 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EPX72099.1 - 1.7e-17 63.7 0.1 3.5e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EPX72099.1 - 1.1e-08 34.6 0.0 2.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 EPX72099.1 - 0.097 13.2 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain adh_short_C2 PF13561.1 EPX72100.1 - 7.4e-33 114.2 0.0 8.6e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPX72100.1 - 6.8e-28 97.6 0.0 8.3e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPX72100.1 - 5.7e-10 39.1 0.0 7.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPX72100.1 - 0.0013 18.1 0.0 0.0024 17.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EPX72100.1 - 0.038 13.1 0.0 0.051 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EPX72100.1 - 0.05 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cid2 PF09774.4 EPX72102.1 - 8e-36 123.4 1.7 9e-36 123.2 1.2 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 UQ_con PF00179.21 EPX72103.1 - 1.3e-17 63.4 0.0 1.5e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPX72103.1 - 0.024 14.5 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain HSP20 PF00011.16 EPX72104.1 - 3.8e-19 68.4 0.0 4.4e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 EPX72104.1 - 0.02 14.4 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) CS PF04969.11 EPX72104.1 - 0.046 14.2 0.0 0.077 13.5 0.0 1.4 1 1 0 1 1 1 0 CS domain NARP1 PF12569.3 EPX72105.1 - 1.1e-176 588.5 22.5 6.8e-175 582.7 13.7 2.5 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EPX72105.1 - 3.7e-11 42.5 23.6 0.024 14.2 0.3 6.7 6 1 0 6 6 6 3 TPR repeat TPR_2 PF07719.12 EPX72105.1 - 6.3e-10 38.2 18.4 1.7 8.7 0.1 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 EPX72105.1 - 1.3e-09 37.8 17.8 0.029 14.3 0.2 6.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPX72105.1 - 7.4e-09 36.0 17.5 1.9 9.2 0.1 7.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPX72105.1 - 1.3e-08 35.0 20.6 0.02 15.1 1.4 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPX72105.1 - 1.2e-07 31.3 3.3 3.6 8.0 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPX72105.1 - 9.4e-06 25.8 15.1 3.2 8.6 0.1 8.1 6 2 3 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPX72105.1 - 8.3e-05 22.3 5.2 1.2 9.0 0.0 5.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPX72105.1 - 0.0088 16.4 16.5 0.7 10.4 0.3 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPX72105.1 - 0.026 14.2 10.2 1.2 9.1 0.3 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF3366 PF11846.3 EPX72105.1 - 0.034 14.0 3.7 0.47 10.3 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) TPR_4 PF07721.9 EPX72105.1 - 0.079 13.4 1.2 12 6.6 0.1 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Rad50_zn_hook PF04423.9 EPX72105.1 - 0.13 11.7 2.8 0.41 10.1 1.9 1.9 1 0 0 1 1 1 0 Rad50 zinc hook motif Fis1_TPR_C PF14853.1 EPX72105.1 - 0.96 9.3 12.6 3.7 7.4 0.0 5.7 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 EPX72105.1 - 2.4 7.9 23.7 6.8 6.4 0.4 7.7 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPX72105.1 - 9.7 6.2 12.1 1 9.3 0.5 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SAE2 PF08573.5 EPX72106.1 - 1.7e-10 41.4 1.0 4.7e-10 40.0 0.0 2.2 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Lzipper-MIP1 PF14389.1 EPX72106.1 - 0.015 15.4 2.3 0.033 14.2 1.6 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Rho_Binding PF08912.6 EPX72106.1 - 0.096 12.9 3.6 0.2 11.9 2.5 1.5 1 0 0 1 1 1 0 Rho Binding COX4 PF02936.9 EPX72107.1 - 2.9e-48 163.2 0.1 3.6e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Methyltransf_16 PF10294.4 EPX72108.1 - 6.9e-19 67.9 0.0 1.1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EPX72108.1 - 2.4e-05 24.8 0.0 4.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX72108.1 - 0.0006 19.5 0.0 0.0023 17.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPX72108.1 - 0.0072 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EPX72108.1 - 0.018 14.6 0.0 0.055 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EPX72108.1 - 0.028 13.7 0.0 0.089 12.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Inhibitor_I9 PF05922.11 EPX72109.1 - 8.9e-11 42.2 0.5 1.7e-10 41.2 0.3 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 PASTA PF03793.14 EPX72109.1 - 0.046 13.3 0.1 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 PASTA domain AA_permease_N PF08403.5 EPX72109.1 - 0.094 12.0 0.0 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 Amino acid permease N-terminal COG4 PF08318.7 EPX72110.1 - 2.2e-86 289.6 3.4 4.4e-86 288.6 2.3 1.5 1 0 0 1 1 1 1 COG4 transport protein PfkB PF00294.19 EPX72111.1 - 2e-67 227.4 0.3 2.5e-67 227.1 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase cNMP_binding PF00027.24 EPX72111.1 - 0.041 13.7 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DEC-1_C PF04626.8 EPX72111.1 - 0.057 13.5 0.1 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Dec-1 protein, C terminal region PS_pyruv_trans PF04230.8 EPX72111.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase DDOST_48kD PF03345.9 EPX72112.1 - 3.7e-126 421.0 0.0 4.3e-126 420.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta F-box PF00646.28 EPX72113.1 - 3e-11 42.6 0.4 3e-11 42.6 0.3 4.4 5 0 0 5 5 5 1 F-box domain F-box-like PF12937.2 EPX72113.1 - 8.3e-11 41.4 0.6 8.6e-10 38.1 0.0 2.8 2 0 0 2 2 2 1 F-box-like TPR_11 PF13414.1 EPX72113.1 - 7.7e-07 28.6 2.0 4e-06 26.3 0.1 2.3 1 1 1 2 2 2 1 TPR repeat LRR_8 PF13855.1 EPX72113.1 - 6.6e-05 22.5 4.0 6.6e-05 22.5 2.8 3.8 2 2 2 4 4 4 2 Leucine rich repeat NARP1 PF12569.3 EPX72113.1 - 0.00013 20.9 0.0 0.00026 19.8 0.0 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 LRR_4 PF12799.2 EPX72113.1 - 0.00028 20.4 19.9 0.00031 20.2 0.7 5.6 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EPX72113.1 - 0.00055 19.7 9.9 0.5 10.5 0.1 5.2 6 0 0 6 6 6 2 Leucine Rich repeat TPR_9 PF13371.1 EPX72113.1 - 0.0082 15.9 1.5 0.016 15.0 1.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPX72113.1 - 0.024 15.2 1.9 0.31 11.8 1.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPX72113.1 - 0.025 14.1 5.9 0.94 9.1 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPX72113.1 - 0.029 14.2 6.4 3.3 7.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_7 PF13504.1 EPX72113.1 - 0.12 12.6 8.6 10 6.8 0.1 5.4 6 0 0 6 6 5 0 Leucine rich repeat LRR_1 PF00560.28 EPX72113.1 - 0.66 10.2 13.7 3.3 8.0 0.1 5.0 5 1 0 5 5 4 0 Leucine Rich Repeat Rad21_Rec8_N PF04825.8 EPX72114.1 - 3.2e-42 142.9 0.1 5.8e-42 142.1 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EPX72114.1 - 1.4e-11 43.3 0.0 3.3e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EPX72114.1 - 0.079 12.5 2.3 0.16 11.5 0.0 2.4 3 0 0 3 3 3 0 ScpA/B protein Apc5 PF12862.2 EPX72116.1 - 1.6e-31 108.0 1.7 1.6e-31 108.0 1.2 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 Ribosomal_L21e PF01157.13 EPX72117.1 - 2.1e-40 136.4 5.3 3.3e-40 135.8 3.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Ribosomal_S4e PF00900.15 EPX72118.1 - 9.7e-34 114.8 0.7 1.8e-33 113.9 0.5 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EPX72118.1 - 8.9e-19 67.0 6.4 1.9e-18 65.9 4.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EPX72118.1 - 2.2e-06 27.0 0.0 5.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EPX72118.1 - 0.00074 19.1 0.4 0.00074 19.1 0.3 2.7 3 0 0 3 3 3 1 KOW motif Abhydrolase_5 PF12695.2 EPX72119.1 - 1.1e-06 28.4 0.0 2.8e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPX72119.1 - 0.084 12.0 0.1 5.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioredoxin PF00085.15 EPX72120.1 - 9.4e-18 63.8 0.0 5.7e-10 38.8 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 EPX72120.1 - 2.2e-11 43.9 0.0 4e-05 23.4 0.0 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain HyaE PF07449.6 EPX72120.1 - 0.014 15.2 0.0 2.7 7.9 0.0 2.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Glyco_transf_15 PF01793.11 EPX72121.1 - 1.5e-40 139.1 0.7 1.9e-40 138.8 0.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Sen15 PF09631.5 EPX72122.1 - 9.2e-25 86.8 0.1 1.2e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein BING4CT PF08149.6 EPX72123.1 - 9.7e-40 133.9 0.0 1.9e-37 126.5 0.0 3.2 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 EPX72123.1 - 1.1e-09 37.7 0.0 3.7e-06 26.5 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EPX72123.1 - 2.7e-05 23.1 0.0 5.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region DUF3713 PF12506.3 EPX72123.1 - 0.22 11.5 3.8 7 6.7 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) SNAP PF14938.1 EPX72124.1 - 1.4e-102 342.6 15.2 1.6e-102 342.5 10.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 EPX72124.1 - 0.029 14.8 11.6 3.8 8.1 0.0 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPX72124.1 - 0.065 13.9 15.4 0.14 12.8 2.0 3.9 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPX72124.1 - 2.2 9.1 10.4 46 5.0 0.1 5.2 2 1 3 6 6 6 0 Tetratricopeptide repeat Glyco_hydro_32N PF00251.15 EPX72125.1 - 6.5e-96 321.3 0.6 8e-96 321.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EPX72125.1 - 5.4e-09 36.3 0.0 1.8e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.9 EPX72125.1 - 0.021 13.9 2.0 2.9 6.9 0.1 3.1 2 1 1 3 3 3 0 Glycosyl hydrolases family 43 14-3-3 PF00244.15 EPX72126.1 - 1.4e-114 381.0 8.1 1.7e-114 380.8 5.6 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EPX72126.1 - 0.003 17.1 2.3 1.6 8.2 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF837) DUF3802 PF12290.3 EPX72126.1 - 0.11 12.8 1.8 0.92 9.8 0.1 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3802) Rad51 PF08423.6 EPX72127.1 - 2.7e-120 400.0 0.2 5.1e-120 399.1 0.0 1.5 2 0 0 2 2 2 1 Rad51 RecA PF00154.16 EPX72127.1 - 7.1e-13 48.3 0.1 9.6e-13 47.8 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EPX72127.1 - 3.9e-10 39.4 0.0 5.5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EPX72127.1 - 3.3e-05 23.9 0.0 9.5e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 EPX72127.1 - 7.1e-05 22.0 0.0 0.00013 21.1 0.0 1.5 1 0 0 1 1 1 1 KaiC DUF128 PF01995.11 EPX72127.1 - 0.017 14.0 0.2 0.24 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF128 Abhydrolase_2 PF02230.11 EPX72128.1 - 9.7e-67 224.5 0.1 1.2e-66 224.3 0.1 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EPX72128.1 - 2.5e-10 40.2 0.0 3.3e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPX72128.1 - 6.5e-10 39.2 0.0 2.6e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EPX72128.1 - 0.014 14.2 0.0 0.03 13.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 EPX72128.1 - 0.019 14.5 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EPX72128.1 - 0.023 14.0 0.4 0.027 13.9 0.3 1.3 1 1 0 1 1 1 0 Putative esterase AvrPto PF11592.3 EPX72129.1 - 0.074 12.8 0.1 1.7 8.4 0.0 2.4 1 1 0 2 2 2 0 Central core of the bacterial effector protein AvrPto PBP_sp32 PF07222.7 EPX72129.1 - 1.7 7.7 7.1 0.84 8.7 3.4 1.5 2 0 0 2 2 2 0 Proacrosin binding protein sp32 TBCA PF02970.11 EPX72130.1 - 3e-19 68.8 2.8 3e-19 68.8 1.9 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A PXA PF02194.10 EPX72130.1 - 0.015 14.8 2.0 0.017 14.7 1.4 1.0 1 0 0 1 1 1 0 PXA domain DUF4398 PF14346.1 EPX72130.1 - 0.017 15.1 2.7 0.16 12.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) DUF1664 PF07889.7 EPX72130.1 - 0.023 14.5 1.9 0.029 14.1 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_Gp23 PF10669.4 EPX72130.1 - 0.047 13.8 1.0 0.067 13.2 0.7 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) NPV_P10 PF05531.7 EPX72130.1 - 0.057 13.6 3.2 0.15 12.3 2.2 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein LPP PF04728.8 EPX72130.1 - 1.1 9.0 4.8 0.26 11.0 0.5 1.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Prefoldin_2 PF01920.15 EPX72130.1 - 1.8 8.3 6.7 5.6 6.7 2.3 2.6 1 1 1 2 2 2 0 Prefoldin subunit DUF2508 PF10704.4 EPX72130.1 - 4.7 7.4 5.6 4.6 7.4 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) adh_short PF00106.20 EPX72131.1 - 3.7e-27 95.2 1.1 4.4e-27 95.0 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPX72131.1 - 1.3e-23 84.0 0.0 1.6e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPX72131.1 - 2.2e-09 37.2 0.2 2.9e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPX72131.1 - 0.001 18.5 0.5 0.0014 18.1 0.4 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EPX72131.1 - 0.0022 18.3 0.3 0.0042 17.4 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 EPX72131.1 - 0.0049 16.6 2.5 0.0098 15.6 1.7 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 EPX72131.1 - 0.011 15.4 0.2 0.017 14.7 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.13 EPX72131.1 - 0.026 14.1 0.3 0.043 13.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EPX72131.1 - 0.026 14.5 1.4 0.077 12.9 1.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 EPX72131.1 - 0.041 13.6 0.1 0.082 12.6 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sof1 PF04158.9 EPX72131.1 - 0.065 13.2 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Sof1-like domain YjeF_N PF03853.10 EPX72131.1 - 0.15 11.6 0.4 0.4 10.2 0.3 1.6 1 1 0 1 1 1 0 YjeF-related protein N-terminus Ank_2 PF12796.2 EPX72132.1 - 2.6e-05 24.4 0.2 5.2e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Methyltransf_11 PF08241.7 EPX72132.1 - 0.047 14.1 0.0 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ank_5 PF13857.1 EPX72132.1 - 0.048 13.9 0.1 0.63 10.3 0.0 2.7 2 1 1 3 3 3 0 Ankyrin repeats (many copies) ubiquitin PF00240.18 EPX72133.1 - 6e-19 67.2 0.1 9.5e-19 66.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPX72133.1 - 3.2e-09 36.3 0.3 5.1e-09 35.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 EPX72133.1 - 1.3e-08 34.4 0.0 3e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DUF2407 PF10302.4 EPX72133.1 - 5.5e-05 23.2 0.1 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 EPX72133.1 - 0.016 15.4 0.4 0.043 14.0 0.3 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EPX72133.1 - 0.044 13.6 0.1 0.1 12.4 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 EPX72133.1 - 0.12 12.9 0.1 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Nsp1_C PF05064.8 EPX72134.1 - 3e-33 113.9 0.1 6.8e-33 112.7 0.0 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region ALIX_LYPXL_bnd PF13949.1 EPX72134.1 - 0.0094 14.9 0.5 0.023 13.6 0.3 1.5 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV Nucleoporin_FG PF13634.1 EPX72134.1 - 0.019 15.1 165.5 0.023 14.9 25.1 5.5 1 1 3 4 4 4 0 Nucleoporin FG repeat region Laminin_I PF06008.9 EPX72134.1 - 0.1 11.9 1.1 0.18 11.0 0.8 1.3 1 0 0 1 1 1 0 Laminin Domain I DUF1748 PF08520.5 EPX72135.1 - 6.6e-27 92.9 0.1 7.1e-27 92.8 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) XRN_N PF03159.13 EPX72136.1 - 4.1e-108 360.2 0.5 8.8e-108 359.1 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DUF1675 PF07897.6 EPX72136.1 - 0.67 9.7 9.7 1.4 8.6 6.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CN_hydrolase PF00795.17 EPX72137.1 - 1.9e-33 115.3 0.0 2.8e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ArfGap PF01412.13 EPX72138.1 - 7.5e-31 106.3 0.2 2.2e-30 104.8 0.1 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 EPX72138.1 - 3e-11 43.4 2.2 3.6e-11 43.1 0.2 2.1 2 0 0 2 2 2 1 PH domain CheB_methylest PF01339.12 EPX72138.1 - 0.065 12.6 0.1 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 CheB methylesterase ERp29 PF07749.7 EPX72138.1 - 0.26 11.9 3.4 1 10.0 0.3 3.1 4 0 0 4 4 4 0 Endoplasmic reticulum protein ERp29, C-terminal domain RhoGAP PF00620.22 EPX72139.1 - 1.4e-38 131.9 0.3 4.4e-38 130.2 0.1 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 EPX72139.1 - 1.9e-06 28.0 0.0 4.9e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 PH domain LSM PF01423.17 EPX72140.1 - 1.2e-18 66.3 0.2 1.5e-18 66.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 EPX72141.1 - 1.6e-23 82.2 0.0 2.2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EPX72141.1 - 4e-20 71.3 0.1 1e-19 70.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 WBS_methylT PF12589.3 EPX72142.1 - 5.2e-15 55.6 5.0 9.7e-15 54.8 3.5 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EPX72142.1 - 1e-11 45.1 0.0 2.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX72142.1 - 9.9e-09 35.1 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX72142.1 - 1e-08 34.8 0.0 1.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX72142.1 - 6.6e-07 29.6 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPX72142.1 - 8.5e-07 28.3 0.0 2.2e-06 26.9 0.0 1.6 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EPX72142.1 - 5.7e-06 26.7 0.0 2.9e-05 24.4 0.0 2.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPX72142.1 - 2.2e-05 24.4 0.0 6.1e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX72142.1 - 4.3e-05 24.0 0.0 0.0001 22.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPX72142.1 - 0.0077 15.3 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EPX72142.1 - 0.0082 15.2 0.1 0.02 13.9 0.0 1.8 2 1 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EPX72142.1 - 0.011 15.2 0.1 0.038 13.5 0.0 1.8 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EPX72142.1 - 0.13 11.6 0.1 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Clathrin PF00637.15 EPX72143.1 - 8e-200 654.4 46.4 5.5e-33 113.5 0.7 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EPX72143.1 - 3.3e-30 103.7 1.0 1.6e-29 101.5 0.5 2.5 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 EPX72143.1 - 9.6e-28 94.5 7.9 0.00011 22.2 0.0 6.9 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin-link PF09268.5 EPX72143.1 - 7.2e-09 34.5 0.1 1.9e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 EPX72143.1 - 3.3e-08 32.7 7.3 0.028 13.2 0.0 4.5 5 0 0 5 5 5 3 Coatomer WD associated region TPR_7 PF13176.1 EPX72143.1 - 0.00017 21.1 6.5 2.2 8.2 0.0 7.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPPII_N PF12583.3 EPX72143.1 - 0.13 12.4 1.1 0.35 11.0 0.2 2.1 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Vps39_1 PF10366.4 EPX72143.1 - 2.9 7.9 15.3 0.48 10.4 0.1 5.9 6 1 0 6 6 6 0 Vacuolar sorting protein 39 domain 1 Ribosomal_L18ae PF01775.12 EPX72144.1 - 3.4e-55 185.2 0.8 4.3e-55 184.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain DUF1767 PF08585.7 EPX72145.1 - 2.5e-13 50.1 0.2 4.7e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) HhH-GPD PF00730.20 EPX72146.1 - 6.1e-19 68.2 0.0 1.9e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 EPX72146.1 - 8.2e-15 54.2 0.1 2.2e-14 52.8 0.1 1.7 1 0 0 1 1 1 1 NUDIX domain EndIII_4Fe-2S PF10576.4 EPX72146.1 - 1.2e-05 25.2 4.1 3.8e-05 23.6 2.9 1.9 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH PF00633.18 EPX72146.1 - 0.00026 20.5 0.1 0.00051 19.5 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif Asp PF00026.18 EPX72147.1 - 5.1e-64 216.5 7.9 6.5e-64 216.1 5.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPX72147.1 - 6.3e-09 35.9 0.0 4.8e-08 33.1 0.0 2.4 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EPX72147.1 - 2.7e-08 33.5 0.3 5.5e-06 26.0 0.1 3.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal WD40 PF00400.27 EPX72148.1 - 3.7e-25 86.8 11.7 1e-06 28.3 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat BTV_NS2 PF04514.7 EPX72148.1 - 0.68 8.7 6.9 1 8.1 4.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Prenyltrans PF00432.16 EPX72149.1 - 1.3e-31 107.8 3.4 5.3e-10 38.6 0.0 4.7 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPX72149.1 - 1.6e-23 83.2 5.2 1.5e-10 41.4 0.8 3.0 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPX72149.1 - 0.00026 20.9 0.2 0.034 14.1 0.2 3.0 1 1 3 4 4 4 3 Prenyltransferase-like A2M_comp PF07678.9 EPX72149.1 - 0.11 11.6 0.9 17 4.5 0.1 3.4 3 1 1 4 4 4 0 A-macroglobulin complement component DnaJ PF00226.26 EPX72150.1 - 1.3e-16 60.0 0.9 3e-16 58.9 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain DUF4512 PF14975.1 EPX72150.1 - 0.09 13.6 0.4 1.9 9.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) DUF1049 PF06305.6 EPX72150.1 - 0.35 10.3 1.6 3.4 7.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) PRA1 PF03208.14 EPX72151.1 - 2.9e-07 29.9 5.1 3.7e-07 29.6 3.6 1.1 1 0 0 1 1 1 1 PRA1 family protein Pex24p PF06398.6 EPX72151.1 - 1.8 7.2 6.7 7.4 5.2 0.2 2.0 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF2512 PF10710.4 EPX72151.1 - 6.4 6.2 9.0 13 5.2 6.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2512) Glyco_hydro_47 PF01532.15 EPX72152.1 - 4.6e-154 513.4 4.2 5.3e-154 513.2 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Phage_int_SAM_5 PF13102.1 EPX72153.1 - 0.06 13.3 1.0 0.07 13.1 0.7 1.2 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF1168 PF06658.7 EPX72153.1 - 7.7 6.0 12.0 9.7 5.7 7.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1168) Ribosomal_S6e PF01092.14 EPX72154.1 - 2.7e-64 214.5 0.1 5.4e-64 213.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e RNA_pol_Rpb4 PF03874.11 EPX72156.1 - 2.8e-22 78.9 2.9 3.2e-22 78.7 2.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 LigA PF07746.6 EPX72156.1 - 0.037 14.0 1.3 6.9 6.7 0.3 2.6 1 1 1 2 2 2 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit UspB PF10625.4 EPX72156.1 - 0.14 11.9 0.1 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Universal stress protein B (UspB) PMT PF02366.13 EPX72157.1 - 9.3e-75 251.1 23.1 9.3e-75 251.1 16.0 2.3 2 0 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EPX72157.1 - 2.4e-20 72.8 0.0 3.7e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 MIR domain MFS_1 PF07690.11 EPX72159.1 - 4.3e-31 107.8 43.6 5.9e-25 87.7 14.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX72159.1 - 5.7e-21 74.6 16.0 1.7e-20 73.0 11.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1193 PF06702.7 EPX72159.1 - 0.042 13.2 0.3 0.064 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1193) SurA_N_2 PF13623.1 EPX72159.1 - 0.053 13.4 0.6 0.19 11.7 0.0 2.2 3 0 0 3 3 3 0 SurA N-terminal domain Herpes_UL73 PF03554.8 EPX72159.1 - 0.61 9.9 4.3 0.49 10.2 0.3 2.7 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein Glu_synthase PF01645.12 EPX72160.1 - 1.9e-161 537.1 0.1 2e-160 533.6 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EPX72160.1 - 7e-137 455.9 0.0 9.6e-137 455.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EPX72160.1 - 1.1e-115 385.9 0.0 2.6e-115 384.6 0.0 1.7 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 EPX72160.1 - 8.5e-67 224.0 2.6 8.5e-67 224.0 1.8 1.8 2 0 0 2 2 2 1 GXGXG motif Fer4_20 PF14691.1 EPX72160.1 - 1.8e-22 79.0 0.0 4.2e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EPX72160.1 - 1.6e-20 73.8 0.0 7.2e-20 71.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPX72160.1 - 8.3e-13 48.8 0.2 2.1e-06 27.9 0.1 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPX72160.1 - 1e-07 31.8 0.4 3.1e-07 30.3 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EPX72160.1 - 4.2e-06 26.1 0.0 7.7e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EPX72160.1 - 1.3e-05 24.3 0.1 0.00057 18.9 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPX72160.1 - 3.4e-05 24.1 0.3 0.0015 18.8 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPX72160.1 - 5.6e-05 22.3 0.6 0.00076 18.6 0.0 2.6 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 EPX72160.1 - 6.1e-05 22.0 0.1 0.00025 20.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EPX72160.1 - 8.9e-05 21.1 1.3 0.00011 20.8 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EPX72160.1 - 0.00086 18.4 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPX72160.1 - 0.0014 17.7 0.1 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EPX72160.1 - 0.0018 17.9 0.0 0.017 14.6 0.0 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EPX72160.1 - 0.015 14.4 0.0 0.054 12.6 0.0 1.9 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EPX72160.1 - 0.016 15.4 0.4 1.4 9.2 0.0 2.9 2 0 0 2 2 2 0 Putative NAD(P)-binding FMN_dh PF01070.13 EPX72160.1 - 0.021 13.7 2.3 0.05 12.4 1.6 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase IlvN PF07991.7 EPX72160.1 - 0.024 14.0 0.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 EPX72160.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DJ-1_PfpI PF01965.19 EPX72160.1 - 0.066 12.6 0.0 2.1 7.7 0.0 2.6 1 1 1 2 2 2 0 DJ-1/PfpI family GIDA PF01134.17 EPX72160.1 - 0.12 11.1 3.8 0.083 11.7 0.2 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.14 EPX72160.1 - 0.16 10.1 0.0 1.6 6.8 0.0 2.3 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like ERCC4 PF02732.10 EPX72161.1 - 8e-06 25.6 0.1 1.8e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 ERCC4 domain GDPD PF03009.12 EPX72162.1 - 9.7e-80 267.7 0.7 2.7e-79 266.2 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EPX72162.1 - 1e-24 86.6 0.4 2e-13 50.4 0.2 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPX72162.1 - 4.8e-20 70.3 2.3 3.2e-07 29.8 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EPX72162.1 - 1.4e-18 66.9 0.7 2.5e-06 27.8 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPX72162.1 - 4.4e-14 52.1 0.2 3.7e-06 26.9 0.1 4.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPX72162.1 - 1.6e-13 49.4 0.2 0.011 15.9 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat SPX PF03105.14 EPX72162.1 - 1.3e-05 25.1 12.3 0.00053 19.8 1.8 3.5 2 1 1 3 3 3 2 SPX domain DUF1908 PF08926.6 EPX72162.1 - 0.23 10.1 7.8 2.5 6.7 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1908) RNA_pol_Rpc82 PF05645.8 EPX72164.1 - 1.9e-49 168.5 2.7 3.4e-49 167.6 1.9 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EPX72164.1 - 9.6e-21 73.4 0.9 2.4e-19 68.9 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EPX72164.1 - 2e-11 43.3 0.6 0.00025 20.5 0.2 2.8 2 0 0 2 2 2 2 TFIIE alpha subunit TrmB PF01978.14 EPX72164.1 - 0.0011 18.6 3.8 0.097 12.3 0.0 3.9 5 0 0 5 5 5 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 EPX72164.1 - 0.021 14.4 0.7 0.14 11.7 0.0 2.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain CPSase_L_D3 PF02787.14 EPX72164.1 - 0.18 11.5 2.7 0.32 10.7 0.0 2.5 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain WD40 PF00400.27 EPX72165.1 - 9.3e-17 60.2 10.5 0.00019 21.1 0.1 7.2 8 0 0 8 8 8 4 WD domain, G-beta repeat DUF3639 PF12341.3 EPX72165.1 - 4.1e-09 36.2 0.9 4.1e-09 36.2 0.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 EPX72165.1 - 0.00049 19.8 1.2 0.46 10.1 0.1 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EPX72165.1 - 0.00057 18.8 1.8 0.034 12.9 0.6 2.4 1 1 1 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.11 EPX72165.1 - 0.016 13.5 0.1 2.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain RAB3GAP2_N PF14655.1 EPX72165.1 - 0.064 12.2 0.1 0.34 9.8 0.0 2.1 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3245 PF11595.3 EPX72166.1 - 7.7e-16 58.7 11.1 8.6e-16 58.5 7.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) DUF4414 PF14377.1 EPX72166.1 - 0.055 13.3 3.5 0.06 13.2 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) G-patch_2 PF12656.2 EPX72166.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.5 2 1 0 2 2 2 0 DExH-box splicing factor binding site Vfa1 PF08432.5 EPX72166.1 - 1.2 9.1 10.7 1.8 8.5 7.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PBP1_TM PF14812.1 EPX72166.1 - 1.2 9.4 13.2 0.29 11.4 6.5 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DHHW PF14286.1 EPX72166.1 - 1.4 8.1 4.9 2 7.6 3.4 1.3 1 1 0 1 1 1 0 DHHW protein BC10 PF06726.7 EPX72167.1 - 3e-14 52.7 6.7 4.3e-14 52.2 4.6 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 PUF PF00806.14 EPX72170.1 - 2.8e-56 183.9 7.0 3e-07 29.5 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat YqzH PF14164.1 EPX72170.1 - 0.00036 20.3 0.2 0.0037 17.1 0.0 2.4 2 0 0 2 2 2 1 YqzH-like protein BRCT PF00533.21 EPX72172.1 - 1e-08 35.1 0.0 2.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EPX72172.1 - 2.8e-06 27.0 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.3 EPX72172.1 - 8e-05 22.3 0.6 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) Synaptobrevin PF00957.16 EPX72173.1 - 9.4e-34 114.8 0.9 1.1e-33 114.7 0.6 1.0 1 0 0 1 1 1 1 Synaptobrevin AAA_11 PF13086.1 EPX72174.1 - 4.6e-72 242.3 0.9 1.2e-71 241.0 0.6 1.7 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.2 EPX72174.1 - 1.1e-69 235.3 31.4 3.6e-49 167.4 12.0 2.2 2 0 0 2 2 2 2 SEN1 N terminal AAA_12 PF13087.1 EPX72174.1 - 2.4e-65 219.6 2.4 3.7e-65 219.0 0.5 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPX72174.1 - 2.1e-11 43.4 0.0 1.1e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EPX72174.1 - 1.7e-07 31.0 1.4 0.00043 19.8 0.0 4.0 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EPX72174.1 - 3.5e-06 26.7 0.0 0.0084 15.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.1 EPX72174.1 - 0.0036 17.4 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.10 EPX72174.1 - 0.0072 16.1 1.8 0.071 12.9 0.1 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EPX72174.1 - 0.029 14.0 0.1 0.78 9.3 0.0 2.7 2 0 0 2 2 2 0 Helicase AAA_22 PF13401.1 EPX72174.1 - 0.086 12.9 1.0 3.3 7.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EPX72174.1 - 0.14 11.5 0.0 0.37 10.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ribosomal_L24e PF01246.15 EPX72175.1 - 1.5e-30 104.8 0.3 1.5e-30 104.8 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e ATP-synt_E PF05680.7 EPX72175.1 - 9.5 6.2 11.5 91 3.1 7.9 2.2 1 1 0 1 1 1 0 ATP synthase E chain UCH PF00443.24 EPX72176.1 - 1.1e-52 178.7 0.1 1.4e-52 178.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPX72176.1 - 5.2e-18 65.5 1.6 1.2e-17 64.2 1.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EPX72176.1 - 3.3e-11 42.4 0.0 7.3e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family ARPC4 PF05856.7 EPX72177.1 - 2.6e-73 244.9 3.9 2.9e-73 244.8 2.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) PACT_coil_coil PF10495.4 EPX72178.1 - 2.2e-21 75.5 0.4 8.6e-21 73.6 0.3 2.1 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Microtub_assoc PF07989.6 EPX72178.1 - 6.5e-19 67.5 3.7 6.5e-19 67.5 2.6 9.4 5 3 6 12 12 12 1 Microtubule associated DivIC PF04977.10 EPX72178.1 - 0.0093 15.4 1.1 0.0093 15.4 0.8 14.0 9 3 6 17 17 17 4 Septum formation initiator Reo_sigmaC PF04582.7 EPX72178.1 - 7.3 5.6 40.7 1.8 7.6 4.4 5.4 1 1 4 6 6 6 0 Reovirus sigma C capsid protein NUDIX PF00293.23 EPX72179.1 - 2.8e-16 59.3 0.0 4.1e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Sec7 PF01369.15 EPX72180.1 - 2.4e-09 37.1 1.6 2.4e-09 37.1 1.1 2.4 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 EPX72180.1 - 1.6e-07 31.4 0.0 5.7e-07 29.6 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EPX72180.1 - 5.6e-05 23.2 0.6 0.00023 21.3 0.0 2.4 2 0 0 2 2 2 1 PH domain Rtt106 PF08512.7 EPX72181.1 - 1.2e-22 79.6 0.1 2e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like YcxB PF14317.1 EPX72181.1 - 0.13 11.5 0.7 0.26 10.5 0.1 1.9 2 0 0 2 2 2 0 YcxB-like protein PUF PF00806.14 EPX72182.1 - 1.5e-13 49.3 0.1 0.18 11.3 0.0 7.2 7 0 0 7 7 7 6 Pumilio-family RNA binding repeat DUF1764 PF08576.5 EPX72183.1 - 9.6e-21 74.4 2.7 1.1e-20 74.2 1.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) zf-H2C2_2 PF13465.1 EPX72184.1 - 8.1e-08 32.1 6.8 0.0018 18.4 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPX72184.1 - 1.7e-05 24.8 20.3 0.002 18.3 1.8 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPX72184.1 - 0.00073 19.6 17.4 0.019 15.2 1.2 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPX72184.1 - 0.048 13.5 2.4 0.42 10.5 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPX72184.1 - 0.3 11.2 0.2 0.3 11.2 0.1 3.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPX72184.1 - 1.8 8.8 9.0 0.2 11.9 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type ubiquitin PF00240.18 EPX72185.1 - 2.4e-34 116.5 2.1 2.6e-34 116.4 0.6 1.7 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 EPX72185.1 - 9.3e-25 86.1 2.3 1.8e-24 85.3 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EPX72185.1 - 5.1e-20 70.9 0.7 9.8e-20 70.0 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPX72185.1 - 4.6e-06 26.7 0.5 3.8e-05 23.8 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPX72185.1 - 0.00011 21.9 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EPX72185.1 - 0.00082 19.2 0.5 0.0018 18.1 0.3 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPX72185.1 - 0.0042 17.2 0.5 0.0054 16.8 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2318 PF10080.4 EPX72185.1 - 0.018 14.8 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DZR PF12773.2 EPX72185.1 - 0.023 14.4 0.3 0.04 13.7 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Plexin_cytopl PF08337.7 EPX72185.1 - 0.051 11.8 2.7 1.1 7.4 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2870 PF11069.3 EPX72185.1 - 0.064 13.3 0.2 0.13 12.2 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) OrfB_Zn_ribbon PF07282.6 EPX72185.1 - 0.2 11.3 1.1 0.46 10.1 0.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EPX72185.1 - 0.39 9.9 2.5 0.85 8.9 1.7 1.6 1 1 0 1 1 1 0 zinc-ribbon domain MMtag PF10159.4 EPX72186.1 - 5.7e-26 90.3 7.1 5.7e-26 90.3 4.9 2.5 2 1 1 3 3 3 1 Kinase phosphorylation protein MliC PF09864.4 EPX72186.1 - 0.66 9.7 2.9 1.3 8.7 2.0 1.6 1 1 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Glyco_hydro_63 PF03200.11 EPX72187.1 - 4.1e-248 825.3 7.7 2.6e-247 822.7 5.3 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EPX72187.1 - 4.2e-06 25.7 0.1 7.8e-06 24.8 0.1 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 EPX72187.1 - 0.0027 16.4 0.0 0.0046 15.7 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Iso_dh PF00180.15 EPX72188.1 - 8.7e-73 245.2 0.0 1e-72 245.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MIF4G_like PF09088.6 EPX72189.1 - 1.4e-72 243.1 3.9 3e-72 242.0 2.7 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EPX72189.1 - 8.8e-35 120.1 7.0 1.8e-34 119.1 4.9 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EPX72189.1 - 0.0013 18.1 1.9 0.0028 17.0 0.1 2.4 3 0 0 3 3 3 1 MIF4G domain DAO PF01266.19 EPX72190.1 - 2.3e-31 109.0 0.0 3e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPX72190.1 - 0.0039 16.9 0.0 0.022 14.5 0.0 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPX72190.1 - 0.015 15.2 0.0 0.19 11.5 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPX72190.1 - 0.049 13.6 0.0 0.093 12.7 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPX72190.1 - 0.066 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EPX72190.1 - 0.086 11.4 0.0 2.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TRAPPC9-Trs120 PF08626.6 EPX72191.1 - 3.3e-249 829.6 20.2 4.3e-249 829.2 14.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_11 PF13414.1 EPX72191.1 - 0.015 14.9 0.0 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.1 EPX72191.1 - 0.034 14.0 0.4 0.09 12.7 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPX72191.1 - 0.056 13.3 0.9 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPX72191.1 - 0.068 12.8 2.0 0.068 12.8 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Y_Y_Y PF07495.8 EPX72191.1 - 0.083 12.6 0.0 0.28 10.9 0.0 1.9 1 0 0 1 1 1 0 Y_Y_Y domain Proteasome PF00227.21 EPX72192.1 - 7.9e-47 159.0 0.0 9.6e-47 158.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPX72192.1 - 5.9e-13 47.8 0.0 1.5e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Abhydrolase_6 PF12697.2 EPX72193.1 - 1.9e-25 90.1 0.0 2.8e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPX72193.1 - 1.1e-20 74.1 0.0 8.9e-15 54.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPX72193.1 - 3.3e-12 46.3 0.0 1.3e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EPX72193.1 - 2.4e-05 24.0 0.0 0.002 17.7 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.6 EPX72193.1 - 0.0001 21.5 0.2 0.0015 17.7 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EPX72193.1 - 0.00013 21.4 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 EPX72193.1 - 0.00055 19.5 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Ndr PF03096.9 EPX72193.1 - 0.00063 18.3 0.0 0.0025 16.3 0.0 1.8 2 0 0 2 2 2 1 Ndr family UPF0227 PF05728.7 EPX72193.1 - 0.003 17.3 0.1 0.008 15.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 EPX72193.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.8 EPX72193.1 - 0.0063 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Thioesterase PF00975.15 EPX72193.1 - 0.014 15.6 0.0 0.59 10.3 0.0 2.4 2 0 0 2 2 2 0 Thioesterase domain DUF2305 PF10230.4 EPX72193.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 EPX72193.1 - 0.025 13.7 0.0 0.78 8.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.8 EPX72193.1 - 0.077 12.4 0.2 6.2 6.2 0.0 2.4 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Kelch_3 PF13415.1 EPX72194.1 - 6e-26 89.9 0.2 7.4e-09 35.5 0.0 4.0 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EPX72194.1 - 2.5e-21 75.1 0.0 1.3e-07 31.4 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 EPX72194.1 - 1.5e-19 69.4 0.7 1.5e-10 40.6 0.1 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EPX72194.1 - 1e-18 66.5 0.7 5.7e-07 29.4 0.0 4.0 2 1 1 3 3 3 3 Kelch motif Kelch_2 PF07646.10 EPX72194.1 - 4e-18 64.3 3.1 8.5e-07 28.5 0.1 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.20 EPX72194.1 - 8.8e-18 63.5 0.1 8e-07 28.5 0.0 3.6 3 0 0 3 3 3 3 Kelch motif DUF2018 PF09442.5 EPX72194.1 - 0.11 13.0 13.1 0.49 11.0 0.4 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF2018) Fungal_trans PF04082.13 EPX72195.1 - 3.3e-28 98.2 4.8 3.3e-28 98.2 3.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX72195.1 - 9.3e-11 41.4 11.6 2.2e-10 40.2 8.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FCH PF00611.18 EPX72195.1 - 0.022 14.9 1.2 0.12 12.5 0.2 2.2 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain NOB1_Zn_bind PF08772.6 EPX72196.1 - 1.6e-30 104.7 2.5 3.5e-30 103.6 1.7 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EPX72196.1 - 0.0076 16.1 15.9 0.044 13.6 11.0 2.1 1 1 0 1 1 1 1 Drug resistance and apoptosis regulator DZR PF12773.2 EPX72196.1 - 0.034 13.9 0.4 0.07 12.9 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon RWD PF05773.17 EPX72197.1 - 2.6e-17 62.7 0.0 7.5e-17 61.2 0.0 1.8 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EPX72197.1 - 2e-16 59.6 17.5 1.5e-11 43.9 3.5 3.8 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EPX72197.1 - 0.0004 20.3 12.4 0.0004 20.3 8.6 4.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX72197.1 - 0.0013 18.4 14.2 0.0013 18.4 9.8 4.4 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPX72197.1 - 0.0019 18.0 13.1 0.0019 18.0 9.0 4.1 3 2 1 4 4 4 1 Ring finger domain Med6 PF04934.9 EPX72198.1 - 1.4e-47 160.8 0.7 1.8e-47 160.4 0.5 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component UPRTase PF14681.1 EPX72199.1 - 8.3e-56 188.4 0.0 8.5e-49 165.5 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EPX72199.1 - 4.2e-09 36.1 0.0 6.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1688 PF07958.6 EPX72200.1 - 9.9e-147 488.8 0.0 1.1e-146 488.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF2419 PF10343.4 EPX72200.1 - 0.05 12.8 0.0 6.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2419) GTP_CH_N PF12471.3 EPX72201.1 - 1.4e-88 295.5 0.0 2.3e-88 294.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EPX72201.1 - 3.6e-16 58.8 0.0 5.4e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II FlgM PF04316.8 EPX72201.1 - 0.099 12.6 0.0 0.44 10.5 0.0 2.0 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Zn_clus PF00172.13 EPX72202.1 - 1.5e-07 31.2 7.6 3.8e-07 29.8 5.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EPX72202.1 - 2.8 8.1 9.0 12 6.1 1.8 2.8 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region UPRTase PF14681.1 EPX72203.1 - 3.8e-68 228.7 0.0 4.3e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Transp_cyt_pur PF02133.10 EPX72204.1 - 1.1e-164 548.1 41.5 1.3e-164 547.9 28.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin WI12 PF07107.6 EPX72204.1 - 0.03 14.2 1.2 0.082 12.8 0.1 2.1 2 0 0 2 2 2 0 Wound-induced protein WI12 PTPLA PF04387.9 EPX72205.1 - 3.2e-50 169.7 13.5 6e-50 168.8 9.3 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA LSM PF01423.17 EPX72206.1 - 3.7e-14 52.0 0.1 4.6e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF2392 PF10288.4 EPX72207.1 - 9.2e-23 80.6 0.0 2.1e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 EPX72207.1 - 2.9e-06 26.9 0.7 0.0098 15.4 0.0 2.9 4 0 0 4 4 4 2 PP-loop family PADR1 PF08063.7 EPX72207.1 - 0.052 12.9 1.3 0.21 11.0 0.9 2.1 1 0 0 1 1 1 0 PADR1 (NUC008) domain DUF4441 PF14536.1 EPX72207.1 - 0.11 12.4 2.9 0.11 12.5 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) DZR PF12773.2 EPX72207.1 - 3.3 7.6 9.3 4.5 7.1 0.8 3.1 2 1 0 2 2 2 0 Double zinc ribbon L51_S25_CI-B8 PF05047.11 EPX72208.1 - 4e-10 39.2 0.0 7.3e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF2404 PF10296.4 EPX72209.1 - 0.00069 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) BAR PF03114.13 EPX72210.1 - 3.6e-42 144.4 9.1 3.6e-42 144.4 6.3 1.7 2 0 0 2 2 2 1 BAR domain SH3_9 PF14604.1 EPX72210.1 - 3.1e-14 52.2 0.1 9.2e-14 50.7 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPX72210.1 - 4.8e-13 48.2 0.2 1.3e-12 46.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPX72210.1 - 2.3e-08 33.3 0.0 4.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF818 PF05677.7 EPX72210.1 - 0.053 12.2 0.1 0.086 11.5 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) SPOUT_MTase PF02590.12 EPX72210.1 - 0.085 12.5 1.3 0.2 11.3 0.9 1.6 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Alb1 PF09135.6 EPX72210.1 - 2 9.0 7.1 0.48 11.0 1.1 2.5 2 0 0 2 2 2 0 Alb1 DUF2014 PF09427.5 EPX72211.1 - 1.9e-64 217.3 2.0 2.6e-64 216.8 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EPX72211.1 - 9.8e-19 66.8 0.5 2.2e-18 65.6 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CENP-Q PF13094.1 EPX72211.1 - 0.00095 19.2 0.8 0.0022 18.0 0.6 1.6 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_1 PF00170.16 EPX72211.1 - 0.0087 15.9 0.1 0.023 14.6 0.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor PRP38 PF03371.10 EPX72212.1 - 1e-59 201.0 0.1 1.3e-59 200.7 0.1 1.0 1 0 0 1 1 1 1 PRP38 family F_bP_aldolase PF01116.15 EPX72213.1 - 2.2e-93 312.4 0.0 2.5e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Pkinase PF00069.20 EPX72215.1 - 7.9e-59 198.9 0.0 1.2e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72215.1 - 1.7e-25 89.5 0.0 6.3e-25 87.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX72215.1 - 2.9e-06 26.4 0.0 7.5e-05 21.8 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPX72215.1 - 0.00039 19.5 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX72215.1 - 0.00044 20.0 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cnl2_NKP2 PF09447.5 EPX72215.1 - 0.0078 15.8 1.5 2.9 7.6 0.0 2.4 2 0 0 2 2 2 2 Cnl2/NKP2 family protein Choline_kinase PF01633.15 EPX72215.1 - 0.032 13.8 0.1 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 EPX72215.1 - 0.043 12.6 0.3 0.13 11.0 0.0 1.8 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase UCH PF00443.24 EPX72216.1 - 9.1e-34 116.7 3.6 1.4e-33 116.1 2.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPX72216.1 - 1.6e-12 47.4 11.0 1.4e-11 44.3 7.6 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_RNApol_7kD PF03604.8 EPX72217.1 - 1.6e-16 59.4 5.1 2e-16 59.1 3.5 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit TFIIS_C PF01096.13 EPX72217.1 - 0.0021 17.6 1.6 1.3 8.7 0.1 2.2 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) DZR PF12773.2 EPX72217.1 - 0.0032 17.2 0.4 0.0043 16.8 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon NinF PF05810.7 EPX72217.1 - 0.0049 16.6 0.7 0.0063 16.2 0.5 1.1 1 0 0 1 1 1 1 NinF protein HypA PF01155.14 EPX72217.1 - 0.005 16.5 0.2 0.0055 16.3 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 EPX72217.1 - 0.005 16.4 1.2 0.0067 16.0 0.8 1.2 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-C3HC PF07967.8 EPX72217.1 - 0.011 15.5 0.1 0.011 15.4 0.1 1.0 1 0 0 1 1 1 0 C3HC zinc finger-like DUF2318 PF10080.4 EPX72217.1 - 0.021 14.6 0.3 0.025 14.3 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Ribosomal_S27e PF01667.12 EPX72217.1 - 0.023 14.2 0.8 0.03 13.8 0.5 1.2 1 0 0 1 1 1 0 Ribosomal protein S27 Nudix_N_2 PF14803.1 EPX72217.1 - 0.042 13.5 0.8 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal UPF0547 PF10571.4 EPX72217.1 - 0.047 13.3 0.8 0.41 10.3 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Baculo_ME53 PF06061.6 EPX72217.1 - 0.06 12.3 0.3 0.066 12.1 0.2 1.0 1 0 0 1 1 1 0 Baculoviridae ME53 DUF2296 PF10058.4 EPX72217.1 - 0.064 13.0 0.5 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Zn-ribbon_8 PF09723.5 EPX72217.1 - 0.069 13.1 2.1 0.19 11.6 1.5 1.7 1 1 0 1 1 1 0 Zinc ribbon domain Elf1 PF05129.8 EPX72217.1 - 0.072 12.7 0.8 0.22 11.2 0.6 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_2 PF13240.1 EPX72217.1 - 0.09 12.2 0.9 0.31 10.5 0.6 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_6 PF14599.1 EPX72217.1 - 0.094 12.5 1.9 0.26 11.0 1.3 1.7 1 1 0 1 1 1 0 Zinc-ribbon Zn_Tnp_IS1595 PF12760.2 EPX72217.1 - 0.12 12.2 3.1 0.31 10.8 0.3 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF1451 PF07295.6 EPX72217.1 - 0.14 11.9 0.9 0.17 11.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) PhnA_Zn_Ribbon PF08274.7 EPX72217.1 - 0.14 11.9 0.2 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.1 EPX72217.1 - 0.14 11.3 1.8 1.5 8.0 1.4 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-trcl PF13451.1 EPX72217.1 - 0.15 11.7 3.1 5.4 6.7 0.1 2.1 1 1 1 2 2 2 0 Probable zinc-binding domain zf-dskA_traR PF01258.12 EPX72217.1 - 0.16 11.7 1.5 4.6 7.0 0.2 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Zn_ribbon_recom PF13408.1 EPX72217.1 - 0.17 12.1 6.8 1.2 9.4 1.4 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L44 PF00935.14 EPX72217.1 - 0.17 11.8 3.5 0.65 10.0 0.9 2.0 1 1 1 2 2 2 0 Ribosomal protein L44 Cas_CXXC_CXXC PF09706.5 EPX72217.1 - 0.19 11.9 3.0 7.4 6.8 0.3 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Ribosomal_L40e PF01020.12 EPX72217.1 - 0.4 10.3 3.1 0.55 9.8 2.1 1.1 1 0 0 1 1 1 0 Ribosomal L40e family DUF2197 PF09963.4 EPX72217.1 - 0.58 10.1 4.1 9.9 6.2 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-NADH-PPase PF09297.6 EPX72217.1 - 0.77 9.3 4.0 3.3 7.2 2.8 1.9 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_5 PF13719.1 EPX72217.1 - 0.84 9.2 3.6 6.4 6.4 2.5 2.1 1 1 0 1 1 1 0 zinc-ribbon domain DUF35_N PF12172.3 EPX72217.1 - 0.93 9.4 6.3 1.5 8.8 0.1 2.8 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Mu-like_Com PF10122.4 EPX72217.1 - 0.95 8.5 5.0 8.5 5.5 1.2 2.1 1 1 1 2 2 2 0 Mu-like prophage protein Com zf-ISL3 PF14690.1 EPX72217.1 - 1.9 8.6 5.1 1 9.4 0.7 2.0 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Ribosomal_L37e PF01907.14 EPX72217.1 - 4.9 7.0 5.8 14 5.5 2.9 2.0 1 1 1 2 2 2 0 Ribosomal protein L37e DNA_methylase PF00145.12 EPX72218.1 - 2.4e-37 128.8 0.0 8.1e-37 127.0 0.0 1.7 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_18 PF12847.2 EPX72218.1 - 0.082 13.4 0.0 0.33 11.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Sigma70_r4_2 PF08281.7 EPX72218.1 - 0.34 10.4 2.0 2.3 7.7 0.1 3.3 3 1 0 3 3 3 0 Sigma-70, region 4 OB_NTP_bind PF07717.11 EPX72219.1 - 1.4e-29 102.2 0.1 4.9e-29 100.4 0.1 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPX72219.1 - 3.9e-25 87.8 0.6 4.5e-24 84.4 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPX72219.1 - 1.1e-14 54.0 0.0 3.3e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPX72219.1 - 2.5e-08 33.5 0.1 1.7e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPX72219.1 - 2.3e-05 24.5 1.5 0.00073 19.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.17 EPX72219.1 - 0.00075 18.9 0.0 0.0081 15.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 EPX72219.1 - 0.0034 17.1 0.1 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 EPX72219.1 - 0.0075 15.1 0.0 0.016 14.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF4299 PF14132.1 EPX72220.1 - 0.044 12.9 0.1 0.057 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) LsmAD PF06741.8 EPX72221.1 - 2.3e-27 94.8 1.2 2.3e-27 94.8 0.8 2.7 2 0 0 2 2 2 1 LsmAD domain DUF202 PF02656.10 EPX72223.1 - 4.2e-13 49.3 3.8 4.2e-13 49.3 2.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 EPX72223.1 - 0.15 10.5 0.1 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DDE_1 PF03184.14 EPX72224.1 - 3.4e-54 183.2 0.9 7.4e-54 182.1 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EPX72224.1 - 8.5e-14 51.1 2.4 1.1e-13 50.8 0.2 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain WD40 PF00400.27 EPX72225.1 - 2.4e-47 157.1 11.3 2.2e-13 49.5 0.1 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EPX72225.1 - 5e-05 21.6 4.3 0.17 9.9 0.0 4.1 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPX72225.1 - 0.00075 18.3 0.2 2.2 6.9 0.0 3.8 1 1 2 3 3 3 2 Nup133 N terminal like Hira PF07569.6 EPX72225.1 - 0.0099 15.1 0.1 0.96 8.6 0.0 3.0 1 1 2 3 3 3 1 TUP1-like enhancer of split Vezatin PF12632.2 EPX72226.1 - 1.1e-13 50.8 9.3 1.3e-13 50.5 5.9 1.4 1 1 0 1 1 1 1 Mysoin-binding motif of peroxisomes CorA PF01544.13 EPX72226.1 - 0.06 12.3 0.0 0.16 10.9 0.0 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Glyco_hydro_16 PF00722.16 EPX72227.1 - 9.4e-09 34.8 0.0 6.1e-08 32.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Acatn PF13000.2 EPX72229.1 - 5.8e-176 586.2 39.6 1.7e-90 304.1 11.2 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 EF_assoc_1 PF08355.7 EPX72229.1 - 0.042 13.1 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 EF hand associated DUF2638 PF10937.3 EPX72230.1 - 8.3e-08 33.2 1.2 9.3e-07 29.8 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2638) TM1586_NiRdase PF14512.1 EPX72230.1 - 0.15 11.2 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Putative TM nitroreductase Ribosomal_S4e PF00900.15 EPX72231.1 - 9.7e-34 114.8 0.7 1.8e-33 113.9 0.5 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EPX72231.1 - 8.9e-19 67.0 6.4 1.9e-18 65.9 4.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EPX72231.1 - 2.2e-06 27.0 0.0 5.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EPX72231.1 - 0.00074 19.1 0.4 0.00074 19.1 0.3 2.7 3 0 0 3 3 3 1 KOW motif DPM2 PF07297.7 EPX72232.1 - 2.1e-22 79.1 3.0 2.2e-22 79.1 2.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EPX72232.1 - 0.0032 17.0 4.6 0.0036 16.9 3.2 1.1 1 0 0 1 1 1 1 PIG-P DUF4246 PF14033.1 EPX72233.1 - 0.0084 14.7 0.1 0.0098 14.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Homeobox PF00046.24 EPX72234.1 - 8.4e-14 50.9 5.1 8.4e-14 50.9 3.5 2.1 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 EPX72234.1 - 0.021 13.8 1.6 1.3 8.1 0.2 2.7 2 1 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez RNA_pol_Rpb1_1 PF04997.7 EPX72235.1 - 4.7e-125 417.3 0.0 7.2e-125 416.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EPX72235.1 - 2.5e-108 361.5 0.1 4e-108 360.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EPX72235.1 - 2.2e-70 235.9 0.0 5e-70 234.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EPX72235.1 - 7.8e-67 224.6 0.9 1.5e-66 223.6 0.7 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.7 EPX72235.1 - 2.3e-50 169.7 3.2 4.3e-50 168.9 2.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.13 EPX72235.1 - 7.9e-50 168.6 0.0 1.6e-49 167.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EPX72235.1 - 5e-39 132.3 0.1 1.3e-38 131.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EPX72235.1 - 1.6e-12 46.4 349.8 0.27 11.4 10.3 18.2 6 2 1 19 19 19 13 RNA polymerase Rpb1 C-terminal repeat HMG_box_2 PF09011.5 EPX72236.1 - 1.6e-17 63.5 2.4 6.1e-17 61.7 1.7 2.1 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 EPX72236.1 - 1.9e-14 53.6 2.2 3.8e-14 52.6 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_5 PF14887.1 EPX72236.1 - 0.00096 18.9 0.4 0.00096 18.9 0.3 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box 5 TryThrA_C PF12319.3 EPX72236.1 - 0.0066 15.6 1.3 0.015 14.5 0.9 1.5 1 0 0 1 1 1 1 Tryptophan-Threonine-rich plasmodium antigen C terminal FancD2 PF14631.1 EPX72236.1 - 6.4 3.7 5.8 10 3.0 4.0 1.3 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Ada3 PF10198.4 EPX72237.1 - 4.7e-33 113.7 7.7 1.2e-32 112.3 5.3 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 TFIIA PF03153.8 EPX72238.1 - 1.5e-66 225.8 1.9 1.8e-66 225.5 1.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Sel1 PF08238.7 EPX72239.1 - 4.6e-21 74.7 21.9 0.004 17.7 0.0 9.6 10 0 0 10 10 10 6 Sel1 repeat TPR_11 PF13414.1 EPX72239.1 - 0.48 10.1 20.1 0.44 10.2 0.7 5.0 6 0 0 6 6 6 0 TPR repeat TPR_17 PF13431.1 EPX72239.1 - 1.8 8.9 7.6 4.6 7.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPX72239.1 - 2.1 9.0 6.8 3.6 8.3 0.6 3.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPX72239.1 - 3.4 7.6 11.1 2.4 8.1 0.1 5.5 6 1 0 6 6 6 0 Tetratricopeptide repeat Mei5 PF10376.4 EPX72240.1 - 4.9e-35 121.0 0.0 7.5e-34 117.1 0.0 1.9 1 1 1 2 2 2 1 Double-strand recombination repair protein DUF2404 PF10296.4 EPX72241.1 - 0.00029 20.9 0.0 0.45 10.6 0.0 2.6 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) Aldo_ket_red PF00248.16 EPX72242.1 - 3.1e-41 141.0 0.0 4.2e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BCAS2 PF05700.6 EPX72243.1 - 8e-40 136.6 2.2 9.3e-40 136.4 1.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Kinetocho_Slk19 PF12709.2 EPX72243.1 - 0.0099 15.9 2.6 0.0099 15.9 1.8 1.6 2 0 0 2 2 2 1 Central kinetochore-associated L-fibroin PF05849.6 EPX72243.1 - 0.023 14.0 0.0 0.036 13.4 0.0 1.5 1 1 0 1 1 1 0 Fibroin light chain (L-fibroin) Pro_isomerase PF00160.16 EPX72244.1 - 4.3e-48 163.4 0.1 4.8e-48 163.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MitMem_reg PF13012.1 EPX72245.1 - 0.029 14.4 3.9 0.058 13.4 2.7 1.5 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Uds1 PF15456.1 EPX72246.1 - 9.3e-26 90.2 4.2 9.3e-26 90.2 2.9 4.9 3 2 2 5 5 5 3 Up-regulated During Septation ATP-sulfurylase PF01747.12 EPX72247.1 - 1.3e-86 289.4 0.1 1.8e-86 288.9 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EPX72247.1 - 2.6e-52 176.4 0.0 4.3e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Romo1 PF10247.4 EPX72248.1 - 1.2e-27 95.9 6.8 1.5e-27 95.5 4.7 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 UPF0300 PF08594.5 EPX72249.1 - 0.00058 18.8 0.1 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) DASH_Ask1 PF08655.5 EPX72250.1 - 1.2e-30 105.1 0.1 2.6e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 DASH complex subunit Ask1 PGA2 PF07543.7 EPX72251.1 - 6.1e-36 123.2 0.6 6.9e-36 123.1 0.4 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF2183 PF09949.4 EPX72252.1 - 4.8e-26 90.6 0.0 1.2e-25 89.2 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) KOW PF00467.24 EPX72253.1 - 9.6e-08 31.4 0.8 1.6e-07 30.7 0.2 1.7 2 0 0 2 2 2 1 KOW motif OPT PF03169.10 EPX72254.1 - 7.7e-195 648.9 51.5 8.9e-195 648.7 35.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Aft1_HRA PF11786.3 EPX72255.1 - 3.5e-19 68.8 11.1 3.5e-19 68.8 7.7 3.0 2 1 1 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.3 EPX72255.1 - 3.4e-12 47.2 3.1 3.4e-12 47.2 2.1 3.6 2 1 0 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.16 EPX72255.1 - 1e-10 41.4 4.2 1.6e-10 40.7 2.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 EPX72255.1 - 7.5e-09 35.9 5.6 7.5e-09 35.9 3.9 4.2 4 1 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EPX72255.1 - 2.9e-07 30.2 4.7 5.2e-07 29.3 3.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF3469 PF11952.3 EPX72255.1 - 0.0014 18.2 0.3 0.0024 17.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3469) bZIP_Maf PF03131.12 EPX72255.1 - 0.053 13.8 3.7 0.12 12.6 2.6 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor C2 PF00168.25 EPX72256.1 - 8.3e-12 44.7 0.0 1.5e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain MBF1 PF08523.5 EPX72257.1 - 6.5e-24 83.7 0.3 6.5e-24 83.7 0.2 1.8 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EPX72257.1 - 2.1e-11 43.4 0.1 4.6e-11 42.3 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.1 EPX72257.1 - 1.6e-05 24.9 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EPX72257.1 - 0.0056 16.6 0.0 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.1 EPX72257.1 - 0.044 13.5 0.1 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3808 PF10300.4 EPX72258.1 - 3.2e-117 391.9 0.0 4.5e-117 391.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DUF2892 PF11127.3 EPX72258.1 - 0.012 15.3 2.9 1 9.2 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2892) UPF0300 PF08594.5 EPX72259.1 - 0.00061 18.7 0.1 0.0013 17.7 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0300) Rep_fac_C PF08542.6 EPX72260.1 - 4.1e-18 65.1 0.2 7.3e-17 61.1 0.0 2.6 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPX72260.1 - 1.1e-13 51.1 0.2 2.3e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EPX72260.1 - 1.7e-07 31.5 0.8 2.3e-06 27.8 0.2 2.7 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EPX72260.1 - 1.2e-05 24.2 0.1 0.00036 19.3 0.0 2.1 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein DNA_pol3_delta PF06144.8 EPX72260.1 - 0.00026 20.5 1.5 0.00048 19.6 1.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EPX72260.1 - 0.00082 19.4 0.5 0.0052 16.7 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPX72260.1 - 0.001 19.2 2.3 0.015 15.4 0.2 2.6 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 EPX72260.1 - 0.005 17.1 0.0 0.0094 16.2 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 EPX72260.1 - 0.033 13.6 0.0 0.32 10.3 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain Bac_DnaA PF00308.13 EPX72260.1 - 0.04 13.5 3.0 3.3 7.2 2.1 2.7 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_19 PF13245.1 EPX72260.1 - 0.062 13.0 0.1 0.87 9.3 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Mito_carr PF00153.22 EPX72261.1 - 8.3e-32 108.7 2.8 4.3e-15 55.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.11 EPX72262.1 - 1.9e-34 118.5 7.8 1.9e-34 118.5 5.4 2.4 2 1 1 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EPX72262.1 - 2.3e-11 43.1 18.6 1.1e-10 40.9 12.9 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPX72262.1 - 4.2e-10 39.7 31.9 1.6e-05 24.9 5.2 3.1 1 1 1 3 3 3 2 EamA-like transporter family Multi_Drug_Res PF00893.14 EPX72262.1 - 0.018 15.5 1.8 0.018 15.5 1.3 3.2 3 1 1 4 4 4 0 Small Multidrug Resistance protein UPF0546 PF10639.4 EPX72262.1 - 0.47 10.2 7.7 2.4 7.9 1.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 DUF2012 PF09430.5 EPX72263.1 - 4.2e-24 84.7 0.1 5.9e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 EPX72263.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Enhancin PF03272.8 EPX72263.1 - 0.065 11.1 0.0 0.075 10.9 0.0 1.1 1 0 0 1 1 1 0 Viral enhancin protein DUF4480 PF13715.1 EPX72263.1 - 0.073 13.1 0.1 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4480) GYF PF02213.11 EPX72264.1 - 1.3e-06 27.8 1.5 3.4e-06 26.5 1.0 1.7 1 0 0 1 1 1 1 GYF domain TIP49 PF06068.8 EPX72265.1 - 1.4e-178 593.6 2.9 1.7e-178 593.4 2.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EPX72265.1 - 1.5e-08 34.9 0.1 1e-05 25.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPX72265.1 - 6.1e-07 28.7 1.8 0.0011 18.0 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EPX72265.1 - 2.5e-05 23.5 1.1 0.00033 19.8 0.3 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DnaB_C PF03796.10 EPX72265.1 - 4.6e-05 22.4 0.2 9.8e-05 21.3 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EPX72265.1 - 0.00021 21.3 0.0 0.0012 18.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPX72265.1 - 0.00057 20.0 0.1 1 9.4 0.0 2.5 1 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EPX72265.1 - 0.0042 16.1 0.0 0.0096 15.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EPX72265.1 - 0.0052 16.2 0.0 1 8.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 EPX72265.1 - 0.0067 16.1 0.1 0.68 9.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) CPT PF07931.7 EPX72265.1 - 0.011 15.4 0.4 0.067 12.8 0.3 2.2 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein T2SE PF00437.15 EPX72265.1 - 0.023 13.6 0.6 0.59 8.9 0.1 2.3 1 1 1 2 2 2 0 Type II/IV secretion system protein Mgm101p PF06420.7 EPX72265.1 - 0.024 13.9 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 AAA_28 PF13521.1 EPX72265.1 - 0.026 14.4 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EPX72265.1 - 0.05 12.4 0.2 0.14 10.9 0.1 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 EPX72265.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EPX72265.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain JmjC PF02373.17 EPX72266.1 - 1.6e-28 99.2 0.0 4.9e-28 97.6 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 EPX72266.1 - 3.1e-10 39.3 0.1 7.2e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 jmjN domain Ribosomal_L36 PF00444.13 EPX72267.1 - 2.3e-19 69.0 9.0 2.9e-19 68.7 6.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 RNA12 PF10443.4 EPX72268.1 - 4e-131 437.4 0.0 7.4e-131 436.5 0.0 1.4 1 1 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 EPX72268.1 - 8.3e-08 31.7 0.0 1.1e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 EPX72268.1 - 1.5e-06 28.1 0.0 5.1e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase RRM_6 PF14259.1 EPX72268.1 - 0.00025 20.9 0.0 0.0011 18.8 0.0 2.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX72268.1 - 0.00068 19.4 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 EPX72268.1 - 0.011 15.6 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Apc15p PF05841.6 EPX72269.1 - 5.8e-11 43.1 5.0 1.6e-10 41.8 3.5 1.8 1 1 1 2 2 2 1 Apc15p protein Ribosomal_L37ae PF01780.14 EPX72270.1 - 3.9e-38 129.1 8.2 4.4e-38 129.0 5.7 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 EPX72270.1 - 0.018 14.4 1.3 0.095 12.1 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.1 EPX72270.1 - 0.13 12.5 1.2 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.2 EPX72270.1 - 0.19 11.5 4.3 0.31 10.8 3.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 EPX72270.1 - 0.25 10.9 0.2 0.25 10.9 0.2 1.7 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.5 EPX72270.1 - 0.37 10.7 0.1 0.37 10.7 0.1 1.9 2 0 0 2 2 2 0 Zinc ribbon domain Lar_restr_allev PF14354.1 EPX72270.1 - 0.82 10.0 6.6 7.2 6.9 4.6 2.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-tcix PF14952.1 EPX72270.1 - 3.2 7.1 7.1 1.7 8.0 2.5 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding EF-hand_4 PF12763.2 EPX72271.1 - 4.2e-25 87.4 0.2 3.1e-09 36.4 0.1 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EPX72271.1 - 1.5e-06 28.2 0.2 0.0017 18.4 0.1 4.1 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.1 EPX72271.1 - 4.2e-06 26.1 1.2 0.14 12.1 0.1 3.9 3 0 0 3 3 3 2 EF-hand domain UBA PF00627.26 EPX72271.1 - 2.3e-05 24.0 0.0 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 EPX72271.1 - 0.00012 21.0 1.0 1.4 8.3 0.2 3.9 4 0 0 4 4 4 2 EF hand ADIP PF11559.3 EPX72271.1 - 0.46 10.3 14.5 0.87 9.4 0.0 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 EPX72271.1 - 0.61 7.8 4.7 1 7.1 3.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EPX72271.1 - 1.3 9.3 6.7 28 5.0 0.6 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) NatB_MDM20 PF09797.4 EPX72272.1 - 6.7e-67 225.7 9.8 6.7e-67 225.7 6.8 1.9 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF3802 PF12290.3 EPX72272.1 - 0.013 15.7 3.2 0.21 11.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3802) SURF1 PF02104.10 EPX72273.1 - 3.8e-56 190.2 0.0 4.5e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 SURF1 family Histone PF00125.19 EPX72274.1 - 5.6e-22 77.6 0.1 8.2e-22 77.1 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPX72274.1 - 0.008 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.20 EPX72275.1 - 2e-74 250.0 0.0 2.3e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72275.1 - 2.3e-30 105.5 0.0 2.9e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX72275.1 - 1.2e-05 24.4 0.0 0.00013 21.0 0.0 2.0 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EPX72275.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPX72275.1 - 0.0028 16.5 0.0 0.0059 15.4 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 WW PF00397.21 EPX72276.1 - 0.0058 16.4 0.6 0.0058 16.4 0.4 2.0 3 0 0 3 3 3 1 WW domain Herpes_LMP2 PF07415.6 EPX72276.1 - 4.1 5.8 6.1 5.6 5.4 4.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein CDC50 PF03381.10 EPX72277.1 - 2.6e-92 308.9 0.2 3.1e-92 308.6 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SWIM PF04434.12 EPX72278.1 - 0.16 11.4 1.6 7.1 6.2 0.1 2.4 2 0 0 2 2 2 0 SWIM zinc finger DnaJ PF00226.26 EPX72279.1 - 1.5e-17 63.0 0.1 5.3e-17 61.3 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S15 PF00312.17 EPX72280.1 - 1.9e-20 72.3 0.9 1.9e-20 72.3 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 PA28_alpha PF02251.13 EPX72280.1 - 0.029 14.5 1.0 0.081 13.1 0.3 2.0 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit Dor1 PF04124.7 EPX72281.1 - 3.5e-63 213.1 13.9 5.5e-63 212.4 9.7 1.2 1 0 0 1 1 1 1 Dor1-like family CENP-F_leu_zip PF10473.4 EPX72281.1 - 0.053 13.3 3.6 0.1 12.4 2.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myc-LZ PF02344.10 EPX72281.1 - 0.084 12.5 1.1 0.21 11.2 0.8 1.6 1 0 0 1 1 1 0 Myc leucine zipper domain DUF342 PF03961.8 EPX72281.1 - 1.4 7.2 3.2 2.3 6.5 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Aminotran_1_2 PF00155.16 EPX72282.1 - 1e-62 212.2 0.0 1.2e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EPX72282.1 - 0.0073 14.9 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Alliinase_C PF04864.8 EPX72282.1 - 0.019 13.6 0.0 0.028 13.0 0.0 1.2 1 0 0 1 1 1 0 Allinase Cys_Met_Meta_PP PF01053.15 EPX72282.1 - 0.021 13.0 0.0 0.083 11.1 0.0 1.9 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glycos_transf_1 PF00534.15 EPX72283.1 - 1.5e-24 86.3 0.0 1.9e-23 82.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EPX72283.1 - 4e-07 29.9 0.1 7.1e-06 25.8 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EPX72283.1 - 0.00059 19.9 0.0 0.0027 17.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EPX72283.1 - 0.00062 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EPX72283.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Alpha-amylase PF00128.19 EPX72284.1 - 5.2e-19 68.7 5.6 5.1e-18 65.5 0.1 4.0 3 1 0 3 3 3 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EPX72284.1 - 7.1e-15 55.1 0.1 1.3e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EPX72284.1 - 1.5e-09 37.5 0.0 3.7e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Actin PF00022.14 EPX72285.1 - 6.6e-158 525.2 0.0 7.5e-158 525.0 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EPX72285.1 - 0.061 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fork_head PF00250.13 EPX72286.1 - 9.9e-34 115.2 0.1 2.4e-33 114.0 0.1 1.6 1 0 0 1 1 1 1 Fork head domain DUF4329 PF14220.1 EPX72286.1 - 0.14 12.0 2.1 0.19 11.6 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) Pkinase PF00069.20 EPX72287.1 - 1.1e-68 231.1 0.0 1.6e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72287.1 - 3.3e-33 114.8 0.0 4.9e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX72287.1 - 0.026 13.4 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EPX72287.1 - 0.028 14.1 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EPX72287.1 - 0.057 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 EPX72288.1 - 0.00051 19.8 11.9 1.8 8.5 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat IKI3 PF04762.7 EPX72288.1 - 0.00071 17.5 0.9 0.08 10.7 0.0 3.0 3 1 0 3 3 3 2 IKI3 family eIF2A PF08662.6 EPX72288.1 - 0.0034 17.1 0.4 0.084 12.5 0.0 3.0 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EPX72288.1 - 0.07 12.8 0.1 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Glyco_transf_15 PF01793.11 EPX72289.1 - 4.3e-121 403.9 14.4 5.3e-121 403.6 10.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.27 EPX72290.1 - 4.1e-40 134.2 26.5 2.3e-10 39.9 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat TPR_11 PF13414.1 EPX72291.1 - 1.2e-06 28.0 0.4 2.5e-06 27.0 0.3 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EPX72291.1 - 0.00041 20.0 0.3 0.048 13.5 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPX72291.1 - 0.0011 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPX72291.1 - 0.0018 17.7 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat EOS1 PF12326.3 EPX72291.1 - 0.025 14.2 2.4 0.051 13.2 0.7 2.1 1 1 1 2 2 2 0 N-glycosylation protein DUF2423 PF10338.4 EPX72292.1 - 2.5e-18 65.7 1.5 2.5e-18 65.7 1.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) Fcf1 PF04900.7 EPX72293.1 - 1.8e-37 127.5 1.9 1.8e-37 127.5 1.3 1.5 2 0 0 2 2 2 1 Fcf1 Cdd1 PF11731.3 EPX72293.1 - 0.021 14.7 0.3 0.034 14.0 0.2 1.4 1 0 0 1 1 1 0 Pathogenicity locus Abhydrolase_5 PF12695.2 EPX72294.1 - 8.3e-22 77.5 0.0 1.2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPX72294.1 - 5.4e-16 59.1 0.0 2.7e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPX72294.1 - 3e-08 33.5 0.0 1.1e-05 25.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 EPX72294.1 - 6.4e-08 31.4 0.1 0.0055 15.2 0.1 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EPX72294.1 - 2.2e-07 30.2 0.0 4.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EPX72294.1 - 3.7e-07 30.0 0.8 8.7e-07 28.8 0.1 2.0 2 1 1 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.7 EPX72294.1 - 0.0021 16.8 0.0 0.0031 16.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.8 EPX72294.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.13 EPX72294.1 - 0.018 14.3 0.0 0.087 12.0 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EPX72294.1 - 0.029 13.8 0.1 1.3 8.4 0.1 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 EPX72294.1 - 0.045 13.6 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 EPX72294.1 - 0.063 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EPX72294.1 - 0.088 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S15 PF02129.13 EPX72294.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EPX72294.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_C48 PF02902.14 EPX72295.1 - 1e-32 113.5 0.1 2.1e-32 112.5 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Vfa1 PF08432.5 EPX72296.1 - 8e-38 130.2 0.7 9.1e-38 130.0 0.5 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 GPCR_chapero_1 PF11904.3 EPX72296.1 - 0.0055 15.8 0.9 0.0071 15.5 0.6 1.1 1 0 0 1 1 1 1 GPCR-chaperone DUF3530 PF12048.3 EPX72296.1 - 0.028 13.4 0.7 0.036 13.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Mem_trans PF03547.13 EPX72296.1 - 0.052 11.8 1.2 0.056 11.7 0.8 1.1 1 0 0 1 1 1 0 Membrane transport protein Tom37_C PF11801.3 EPX72296.1 - 0.13 12.1 1.7 0.18 11.6 1.2 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain RAP1 PF07218.6 EPX72296.1 - 0.32 9.0 8.4 0.38 8.7 5.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ICAP-1_inte_bdg PF10480.4 EPX72296.1 - 0.76 9.5 7.7 0.11 12.2 2.5 1.6 1 1 1 2 2 2 0 Beta-1 integrin binding protein Macoilin PF09726.4 EPX72296.1 - 1.2 7.3 8.8 1.4 7.1 6.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 EPX72296.1 - 1.4 6.5 7.9 1.6 6.3 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TYA PF01021.14 EPX72296.1 - 1.7 8.8 8.9 2.5 8.3 6.0 1.4 1 1 0 1 1 1 0 TYA transposon protein SRC-1 PF08832.5 EPX72296.1 - 8.9 7.1 10.8 0.87 10.3 3.1 2.1 1 1 1 2 2 2 0 Steroid receptor coactivator CENP-N PF05238.8 EPX72297.1 - 1.2e-66 225.4 0.0 1.5e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Sarcoglycan_2 PF05510.8 EPX72297.1 - 0.062 11.6 0.1 0.089 11.0 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon S10_plectin PF03501.10 EPX72298.1 - 9.6e-43 143.9 0.1 1.1e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain WD40 PF00400.27 EPX72299.1 - 1e-51 171.0 13.9 3.6e-09 36.1 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EPX72299.1 - 0.014 13.5 6.1 5.1 5.1 2.1 4.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 AAA_17 PF13207.1 EPX72300.1 - 1.1e-07 32.6 0.0 2.2e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPX72300.1 - 2.3e-07 31.1 0.1 1.2e-06 28.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EPX72300.1 - 0.00061 19.4 0.9 0.0023 17.4 0.2 2.1 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EPX72300.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPX72300.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EPX72301.1 - 2.6e-48 163.5 0.0 3.5e-42 143.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EPX72301.1 - 2.2e-07 30.9 0.0 9.8e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPX72301.1 - 1.4e-05 25.1 0.5 0.00015 21.8 0.1 2.8 3 1 0 3 3 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EPX72301.1 - 3.3e-05 23.3 0.0 0.0012 18.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 EPX72301.1 - 8.2e-05 22.7 0.0 0.011 15.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPX72301.1 - 0.0014 18.4 0.0 0.0065 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPX72301.1 - 0.0017 18.1 0.0 0.012 15.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPX72301.1 - 0.0023 18.7 0.2 0.021 15.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPX72301.1 - 0.0069 15.8 0.0 0.019 14.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPX72301.1 - 0.01 16.1 0.3 0.044 14.0 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 EPX72301.1 - 0.014 15.1 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 EPX72301.1 - 0.023 13.7 0.0 0.053 12.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EPX72301.1 - 0.026 13.2 0.0 0.046 12.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 EPX72301.1 - 0.028 14.6 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 1 0 RNA helicase Sigma54_activat PF00158.21 EPX72301.1 - 0.031 13.7 0.0 2 7.8 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.1 EPX72301.1 - 0.035 14.0 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EPX72301.1 - 0.044 12.9 0.1 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EPX72301.1 - 0.084 12.0 0.0 0.24 10.6 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EPX72301.1 - 0.09 12.4 0.1 0.41 10.2 0.1 2.2 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 EPX72301.1 - 0.31 10.5 0.0 0.6 9.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TMEM223 PF14640.1 EPX72302.1 - 4.1e-07 30.0 0.1 6.5e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 223 SKN1 PF03935.10 EPX72303.1 - 3.9e-08 31.9 0.0 5e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) PIRT PF15099.1 EPX72303.1 - 0.02 14.1 0.4 0.041 13.0 0.0 1.7 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family RRM_1 PF00076.17 EPX72304.1 - 1.3e-68 226.5 3.0 3.3e-19 68.2 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX72304.1 - 2e-60 200.6 0.7 5.3e-16 58.3 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX72304.1 - 7e-36 121.8 0.2 3.3e-10 39.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EPX72304.1 - 0.0013 18.4 2.9 36 4.2 0.0 6.1 5 2 0 5 5 5 1 Limkain b1 Anoctamin PF04547.7 EPX72305.1 - 5.4e-88 295.6 17.6 6.3e-88 295.3 12.2 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel DEAD PF00270.24 EPX72306.1 - 2e-37 128.3 0.1 3.9e-37 127.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX72306.1 - 5.1e-21 74.3 0.2 1.7e-20 72.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX72306.1 - 9.4e-07 28.8 0.1 1.5e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EPX72306.1 - 0.0018 18.2 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain PhoH PF02562.11 EPX72306.1 - 0.034 13.3 0.1 0.067 12.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 EPX72306.1 - 0.05 13.3 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 EPX72306.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain CEP19 PF14933.1 EPX72306.1 - 0.16 12.2 1.2 0.71 10.1 0.1 2.4 3 0 0 3 3 3 0 CEP19-like protein Adaptin_N PF01602.15 EPX72307.1 - 6.1e-104 348.2 14.6 7.4e-104 347.9 10.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EPX72307.1 - 1.6e-33 115.0 0.0 5.6e-33 113.2 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EPX72307.1 - 4e-08 33.5 0.3 3.8e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Adaptin C-terminal domain AP4E_app_platf PF14807.1 EPX72307.1 - 0.013 15.7 0.0 0.039 14.1 0.0 1.9 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DNApol3-delta_C PF09115.5 EPX72307.1 - 0.03 14.3 0.8 0.62 10.1 0.0 2.9 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal DUF31 PF01732.11 EPX72307.1 - 0.094 12.0 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) RINT1_TIP1 PF04437.8 EPX72308.1 - 2.9e-78 263.6 22.1 3.6e-78 263.3 15.3 1.1 1 0 0 1 1 1 1 RINT-1 / TIP-1 family zf-DHHC PF01529.15 EPX72309.1 - 1.1e-25 90.0 7.6 1.1e-25 90.0 5.2 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase zf-RING_2 PF13639.1 EPX72310.1 - 2.5e-10 40.0 12.1 4.4e-10 39.2 8.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPX72310.1 - 5.4e-08 32.7 12.2 9.8e-08 31.9 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPX72310.1 - 1.2e-07 31.5 10.1 2.6e-07 30.3 7.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EPX72310.1 - 1.2e-07 31.2 12.1 2e-07 30.5 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX72310.1 - 1.6e-07 30.8 9.1 3.1e-07 30.0 6.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPX72310.1 - 2.2e-07 30.4 8.1 3.8e-07 29.6 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Pex2_Pex12 PF04757.9 EPX72310.1 - 1.9e-06 27.5 5.6 2.5e-06 27.0 3.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_UBOX PF13445.1 EPX72310.1 - 4.7e-05 23.0 3.5 7.6e-05 22.3 1.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EPX72310.1 - 5.2e-05 23.2 10.5 0.00012 22.0 7.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EPX72310.1 - 0.015 15.0 3.1 0.027 14.2 2.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EPX72310.1 - 0.019 14.7 4.8 0.039 13.7 3.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 EPX72310.1 - 0.053 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 U-box domain DUF1394 PF07159.7 EPX72310.1 - 0.089 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) Prok-RING_4 PF14447.1 EPX72310.1 - 7.5 6.1 9.6 20 4.8 6.6 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE PF01363.16 EPX72310.1 - 10 6.1 9.7 8.8 6.3 0.7 2.8 1 1 1 2 2 2 0 FYVE zinc finger BPL_LplA_LipB PF03099.14 EPX72311.1 - 5.2e-22 78.1 0.3 8.2e-22 77.5 0.2 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family TatD_DNase PF01026.16 EPX72312.1 - 3.7e-56 190.1 0.0 4.6e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Pyr_redox_2 PF07992.9 EPX72313.1 - 3.9e-39 134.6 0.0 6.2e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EPX72313.1 - 1.3e-32 112.1 0.2 3.9e-32 110.5 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EPX72313.1 - 2.1e-21 76.1 1.4 1.8e-16 60.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPX72313.1 - 2.4e-11 44.1 0.2 1.3e-09 38.4 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPX72313.1 - 4e-09 36.0 0.1 5.8e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EPX72313.1 - 3.5e-06 26.1 0.1 3.5e-06 26.1 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPX72313.1 - 5.8e-06 25.4 2.3 2.2e-05 23.4 1.5 1.9 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EPX72313.1 - 7.5e-06 25.0 1.0 0.00019 20.4 0.8 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EPX72313.1 - 7.9e-06 25.8 4.0 1.2e-05 25.1 1.7 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EPX72313.1 - 3.7e-05 23.4 0.7 0.0056 16.3 0.0 2.5 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EPX72313.1 - 0.00038 19.0 4.3 0.0015 17.0 0.6 2.9 3 1 1 4 4 4 1 HI0933-like protein Thi4 PF01946.12 EPX72313.1 - 0.0005 19.2 0.6 0.0011 18.0 0.4 1.5 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.1 EPX72313.1 - 0.00061 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EPX72313.1 - 0.0014 18.1 0.3 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EPX72313.1 - 0.003 17.8 0.0 0.25 11.6 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EPX72313.1 - 0.0044 16.7 0.2 0.22 11.2 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 EPX72313.1 - 0.034 13.1 0.6 0.54 9.2 0.4 2.1 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EPX72313.1 - 0.041 13.0 1.6 1.6 7.8 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EPX72313.1 - 0.13 11.1 0.3 0.25 10.2 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 EPX72313.1 - 0.37 10.1 0.1 0.37 10.1 0.0 2.1 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DSPc PF00782.15 EPX72314.1 - 3.2e-35 120.6 0.1 4.8e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPX72314.1 - 4.2e-05 23.0 0.0 6.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EPX72314.1 - 0.022 14.2 0.0 0.082 12.3 0.0 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) TAP35_44 PF07265.6 EPX72314.1 - 0.082 12.6 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 zinc_ribbon_5 PF13719.1 EPX72314.1 - 0.21 11.2 2.9 9.5 5.9 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EPX72314.1 - 0.4 10.3 3.7 11 5.7 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EPX72314.1 - 5.2 6.9 9.7 4 7.3 3.1 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DnaJ PF00226.26 EPX72315.1 - 1.8e-24 85.2 3.5 1.8e-24 85.2 2.4 2.1 2 0 0 2 2 2 1 DnaJ domain DUF1977 PF09320.6 EPX72315.1 - 2.6e-19 69.4 0.8 2.6e-19 69.4 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) TPR_2 PF07719.12 EPX72315.1 - 0.093 12.6 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat CBFB_NFYA PF02045.10 EPX72315.1 - 1.2 9.7 7.8 0.12 12.9 0.5 2.7 3 0 0 3 3 3 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B tRNA-synt_1g PF09334.6 EPX72316.1 - 1.7e-144 481.3 0.3 2.8e-144 480.5 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EPX72316.1 - 1.4e-08 33.2 0.7 2.1e-05 22.7 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Y_phosphatase2 PF03162.8 EPX72317.1 - 2.4e-48 163.6 0.0 3.9e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EPX72317.1 - 1.3e-11 44.9 0.0 9.3e-10 38.9 0.0 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EPX72317.1 - 0.055 12.7 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF2416 PF10315.4 EPX72318.1 - 2.1e-25 89.0 1.1 2.4e-25 88.8 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) DUF979 PF06166.7 EPX72319.1 - 0.0032 16.4 0.3 0.0041 16.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF979) DUF4577 PF15145.1 EPX72319.1 - 0.13 12.2 3.3 1.3 8.9 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) DUF2207 PF09972.4 EPX72319.1 - 6.3 5.2 7.6 1.4 7.3 3.1 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Aldo_ket_red PF00248.16 EPX72320.1 - 2.4e-44 151.2 0.0 2.8e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-RING_2 PF13639.1 EPX72321.1 - 8.3e-15 54.3 6.1 8.3e-15 54.3 4.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPX72321.1 - 1.7e-09 37.2 10.0 2.4e-09 36.6 2.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPX72321.1 - 5.1e-08 32.8 6.8 5.1e-08 32.8 4.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPX72321.1 - 1.5e-07 31.4 1.8 1.5e-07 31.4 1.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPX72321.1 - 3.5e-07 29.8 5.4 3.5e-07 29.8 3.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPX72321.1 - 1.8e-05 24.2 7.0 1.8e-05 24.2 4.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EPX72321.1 - 0.014 15.3 5.7 0.079 12.9 4.0 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EPX72321.1 - 0.067 12.9 2.2 0.21 11.3 1.6 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.1 EPX72321.1 - 0.078 12.7 10.0 0.057 13.1 2.1 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_3 PF14369.1 EPX72321.1 - 0.2 11.7 7.7 0.075 13.0 3.0 2.1 2 0 0 2 2 1 0 zinc-finger Pox_A3L PF05288.6 EPX72321.1 - 0.22 11.2 0.5 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A3L Protein zf-Apc11 PF12861.2 EPX72321.1 - 1 9.2 9.5 0.064 13.0 2.5 2.1 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1180 PF06679.7 EPX72321.1 - 1.4 8.7 7.7 0.089 12.6 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) HypA PF01155.14 EPX72321.1 - 5.6 6.6 5.9 0.66 9.6 0.4 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-P11 PF03854.9 EPX72321.1 - 5.8 6.4 10.0 0.23 10.9 2.3 2.1 2 1 1 3 3 3 0 P-11 zinc finger Fis1_TPR_C PF14853.1 EPX72322.1 - 2e-05 24.3 0.5 3.4e-05 23.6 0.4 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 EPX72322.1 - 0.031 14.1 0.1 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPX72322.1 - 0.071 13.6 0.1 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_N PF14852.1 EPX72322.1 - 0.086 12.1 0.1 0.34 10.2 0.1 2.0 1 1 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat Ribosomal_L18p PF00861.17 EPX72323.1 - 2.6e-43 147.0 0.3 8.4e-43 145.3 0.0 2.0 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EPX72323.1 - 2.1e-30 105.0 3.9 2.1e-30 105.0 2.7 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EPX72323.1 - 0.067 13.2 0.2 0.31 11.1 0.1 2.1 1 1 0 1 1 1 0 Threonine synthase N terminus RRM_1 PF00076.17 EPX72324.1 - 1.2e-12 47.2 0.0 1.8e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX72324.1 - 7.7e-09 35.2 0.0 1.1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX72324.1 - 2e-05 24.4 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPX72324.1 - 0.00058 19.5 0.0 0.00084 19.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ribosomal_L18e PF00828.14 EPX72325.1 - 5.9e-28 97.8 0.3 5.9e-28 97.8 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 DUF2637 PF10935.3 EPX72326.1 - 0.038 13.9 0.1 0.054 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2637) KRE9 PF05390.6 EPX72327.1 - 5.6e-11 42.7 5.0 1.3e-10 41.5 3.5 1.6 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 PLAT PF01477.18 EPX72327.1 - 0.0083 16.4 0.0 0.087 13.2 0.0 2.5 1 1 0 1 1 1 1 PLAT/LH2 domain TFCD_C PF12612.3 EPX72328.1 - 4.3e-14 52.3 2.2 4.5e-13 49.0 0.0 3.5 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EPX72328.1 - 0.0029 17.5 6.1 1.2 9.3 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EPX72328.1 - 0.0061 17.0 0.2 2.8 8.5 0.0 4.2 4 0 0 4 4 4 1 HEAT-like repeat Ndc80_HEC PF03801.8 EPX72329.1 - 5.4e-50 168.9 0.0 1.7e-49 167.3 0.0 1.9 1 0 0 1 1 1 1 HEC/Ndc80p family Reo_sigmaC PF04582.7 EPX72329.1 - 0.00018 20.7 12.0 0.0084 15.3 1.5 2.2 2 0 0 2 2 2 2 Reovirus sigma C capsid protein Leu_zip PF15294.1 EPX72329.1 - 0.017 14.2 45.3 0.059 12.4 17.4 2.1 2 0 0 2 2 2 0 Leucine zipper TPR_MLP1_2 PF07926.7 EPX72329.1 - 0.17 11.6 48.3 0.25 11.1 10.9 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein GDPD PF03009.12 EPX72329.1 - 0.59 9.5 8.8 0.1 12.0 2.7 2.0 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Atg14 PF10186.4 EPX72329.1 - 1.6 7.5 40.5 0.14 11.1 5.3 3.1 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 EPX72329.1 - 2.2 8.7 22.6 0.17 12.2 0.9 4.2 3 2 0 3 3 3 0 SlyX Laminin_II PF06009.7 EPX72329.1 - 4 7.1 37.6 0.048 13.4 6.3 3.3 2 1 1 3 3 3 0 Laminin Domain II FCH PF00611.18 EPX72330.1 - 2.6e-18 65.9 1.6 6.3e-18 64.7 0.1 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EPX72330.1 - 4.5e-11 41.9 0.2 1.1e-10 40.7 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPX72330.1 - 9.1e-11 41.1 0.1 1.7e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPX72330.1 - 2e-09 36.8 0.1 3.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain IncA PF04156.9 EPX72330.1 - 1.3 8.5 11.0 1.1 8.8 0.1 3.3 2 1 0 2 2 2 0 IncA protein DEAD PF00270.24 EPX72334.1 - 1.2e-45 155.0 0.0 5.2e-45 152.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX72334.1 - 1e-26 92.5 0.1 1.2e-25 89.1 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX72334.1 - 0.00061 19.6 0.0 0.00061 19.6 0.0 2.6 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EPX72334.1 - 0.0031 16.6 0.0 0.0031 16.6 0.0 2.6 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit SAPS PF04499.10 EPX72334.1 - 0.026 13.1 10.0 0.04 12.5 4.8 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein AAA_19 PF13245.1 EPX72334.1 - 0.032 13.9 0.5 0.39 10.4 0.1 2.7 2 1 0 2 2 2 0 Part of AAA domain Neur_chan_memb PF02932.11 EPX72334.1 - 0.084 12.7 3.5 0.12 12.2 2.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.13 EPX72334.1 - 0.1 10.8 0.1 0.097 10.9 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein Pox_Ag35 PF03286.9 EPX72334.1 - 0.18 11.2 19.0 0.29 10.6 13.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tim54 PF11711.3 EPX72334.1 - 0.54 8.8 12.6 0.88 8.0 8.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM60A PF15396.1 EPX72334.1 - 7.1 6.3 17.0 12 5.5 11.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A RNase_PH PF01138.16 EPX72336.1 - 2.4e-25 89.3 0.0 3.6e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EPX72336.1 - 5.6e-09 35.8 0.0 9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RRN9 PF10680.4 EPX72337.1 - 1.8e-09 37.2 0.3 7.8e-09 35.1 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor Cut8_C PF08559.5 EPX72337.1 - 0.02 14.7 0.1 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 Cut8 six-helix bundle Diphthamide_syn PF01866.12 EPX72338.1 - 2.2e-73 247.1 0.0 2.8e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MoeZ_MoeB PF05237.8 EPX72338.1 - 0.0033 16.9 0.0 0.0085 15.6 0.0 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain DUF3020 PF11223.3 EPX72339.1 - 1.1e-21 76.9 7.0 1.1e-21 76.9 4.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) DUF1675 PF07897.6 EPX72339.1 - 0.00084 19.3 1.8 0.0016 18.3 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1675) WD40 PF00400.27 EPX72340.1 - 1.1e-14 53.6 16.4 4.9e-05 23.0 0.0 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat PC_rep PF01851.17 EPX72341.1 - 2.8e-40 134.3 18.3 1.2e-06 28.3 0.0 8.9 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EPX72341.1 - 6.1e-11 42.4 1.1 5.4e-07 29.8 0.0 3.7 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EPX72341.1 - 0.0064 16.4 0.5 13 6.2 0.1 3.9 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 EPX72341.1 - 0.012 16.0 0.0 7.5 7.1 0.0 4.4 5 0 0 5 5 5 0 HEAT-like repeat DNA_primase_lrg PF04104.9 EPX72342.1 - 2.6e-85 285.8 0.0 4e-85 285.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit PCI PF01399.22 EPX72343.1 - 4.5e-06 26.9 3.7 8.1e-06 26.1 0.1 3.1 3 0 0 3 3 3 1 PCI domain zf-HC5HC2H_2 PF13832.1 EPX72344.1 - 4.4e-26 91.0 21.7 6.7e-26 90.4 8.4 2.4 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EPX72344.1 - 9.4e-20 70.5 8.3 9.4e-20 70.5 5.8 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EPX72344.1 - 1.9e-13 49.4 2.8 1.9e-13 49.4 2.0 3.1 3 0 0 3 3 3 1 PHD-finger PHD PF00628.24 EPX72344.1 - 5.4e-09 35.6 9.4 5.4e-09 35.6 6.5 3.0 4 0 0 4 4 4 1 PHD-finger EPL1 PF10513.4 EPX72344.1 - 9.5e-05 22.6 0.2 0.0003 21.0 0.1 1.8 1 0 0 1 1 1 1 Enhancer of polycomb-like C1_1 PF00130.17 EPX72344.1 - 0.003 17.2 1.9 0.003 17.2 1.3 3.3 4 0 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CMD PF02627.15 EPX72345.1 - 1.5e-06 27.9 0.0 2.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family zf-rbx1 PF12678.2 EPX72346.1 - 3.9e-12 46.0 1.6 8.1e-12 45.0 1.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPX72346.1 - 1.6e-09 37.4 9.9 1.6e-09 37.4 6.8 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPX72346.1 - 8.1e-08 31.8 5.4 2e-06 27.3 1.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX72346.1 - 4.4e-06 26.2 4.8 9.3e-06 25.2 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX72346.1 - 7.4e-06 25.6 6.2 5.4e-05 22.8 4.5 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPX72346.1 - 1.3e-05 25.1 2.3 1.3e-05 25.1 1.6 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPX72346.1 - 4.3e-05 23.2 1.4 0.00021 21.0 0.5 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EPX72346.1 - 0.00082 19.0 5.3 0.00082 19.0 3.7 2.4 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EPX72346.1 - 0.017 14.6 0.6 0.04 13.4 0.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EPX72346.1 - 0.1 12.2 2.8 0.13 11.8 0.3 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EPX72346.1 - 0.17 11.3 6.4 0.29 10.6 1.9 2.5 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4_4 PF15227.1 EPX72346.1 - 0.78 9.6 8.7 0.26 11.1 1.1 2.8 3 0 0 3 3 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EPX72346.1 - 0.98 9.5 7.3 1.1 9.3 3.3 2.2 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.3 EPX72346.1 - 1.1 9.2 5.2 5.2 7.1 3.6 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Peptidase_C48 PF02902.14 EPX72347.1 - 8.1e-18 64.8 0.0 2e-17 63.5 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Macoilin PF09726.4 EPX72347.1 - 1.7 6.8 6.0 2.3 6.3 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 EPX72347.1 - 4.4 6.2 7.3 6.1 5.7 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cyclin PF08613.6 EPX72348.1 - 1.6e-42 145.4 0.8 1.6e-42 145.4 0.5 2.1 3 1 0 3 3 3 1 Cyclin LSM PF01423.17 EPX72349.1 - 3.2e-16 58.6 0.1 3.6e-16 58.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain UPF0565 PF10561.4 EPX72349.1 - 0.056 12.3 0.0 0.063 12.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF2435 PF10363.4 EPX72350.1 - 2.9e-19 68.7 2.1 1.4e-18 66.5 0.4 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) HEAT_2 PF13646.1 EPX72350.1 - 2.3e-07 30.9 3.8 0.0038 17.4 0.1 4.5 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EPX72350.1 - 0.0044 16.9 0.3 0.5 10.5 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat Nipped-B_C PF12830.2 EPX72350.1 - 0.0071 16.0 1.4 0.15 11.7 0.0 3.2 3 1 0 3 3 3 1 Sister chromatid cohesion C-terminus DUF2411 PF10304.4 EPX72350.1 - 0.041 13.4 3.9 0.056 12.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2411) MUG2_C PF08593.5 EPX72350.1 - 6 7.1 6.9 2.5 8.3 0.5 2.9 3 0 0 3 3 3 0 Meiotically up-regulated glycoproteins C-terminal GRAM PF02893.15 EPX72351.1 - 7.8e-20 70.1 0.0 2e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 GRAM domain HORMA PF02301.13 EPX72352.1 - 3.1e-41 141.1 0.1 3.5e-41 140.9 0.1 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EPX72352.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.7 1 1 0 1 1 1 0 Autophagy-related protein 13 DUF2927 PF11150.3 EPX72352.1 - 0.014 15.1 0.2 0.019 14.6 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2927) NRDE-2 PF08424.5 EPX72353.1 - 2.2e-63 214.0 7.5 2.2e-63 214.0 5.2 2.6 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_17 PF13431.1 EPX72353.1 - 0.031 14.4 0.0 5.4 7.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2594 PF10769.4 EPX72353.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) Nse4_C PF08743.5 EPX72354.1 - 7.8e-27 93.1 0.1 2.1e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EPX72354.1 - 2e-08 33.9 0.1 3.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE IFRD PF05004.8 EPX72355.1 - 2.3e-59 201.0 3.1 3e-59 200.6 2.1 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) DUF1741 PF08427.5 EPX72356.1 - 5.2e-42 143.9 1.6 9.2e-42 143.1 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) His_kinase PF06580.8 EPX72356.1 - 0.0007 19.4 3.6 0.24 11.3 0.1 3.6 4 0 0 4 4 4 2 Histidine kinase Gar1 PF04410.9 EPX72357.1 - 1.2e-43 148.2 0.0 1.5e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 EPX72358.1 - 7.1e-47 159.2 0.2 1.3e-46 158.3 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPX72358.1 - 9.3e-18 63.9 0.1 2e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 EPX72358.1 - 1.5e-12 47.1 0.0 3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 EPX72358.1 - 3.5e-11 42.7 0.0 7.7e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Vac14_Fig4_bd PF11916.3 EPX72359.1 - 1.1e-75 252.7 7.4 3.4e-75 251.1 5.1 1.9 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EPX72359.1 - 1.1e-45 154.0 6.3 8.5e-40 135.0 0.1 5.4 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EPX72359.1 - 3e-13 48.6 0.3 0.15 12.1 0.0 7.0 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.1 EPX72359.1 - 1.9e-06 28.0 0.0 3 8.1 0.0 5.6 4 1 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 EPX72359.1 - 0.00012 22.4 0.0 2.7 8.5 0.0 4.7 4 0 0 4 4 4 1 HEAT-like repeat ParcG PF10274.4 EPX72359.1 - 0.0011 18.8 0.4 0.15 11.9 0.1 2.9 2 0 0 2 2 2 1 Parkin co-regulated protein PSII PF00421.14 EPX72359.1 - 0.021 13.4 0.0 0.036 12.6 0.0 1.3 1 0 0 1 1 1 0 Photosystem II protein AsnA PF03590.10 EPX72359.1 - 0.025 14.0 0.2 0.044 13.2 0.1 1.3 1 0 0 1 1 1 0 Aspartate-ammonia ligase Tim17 PF02466.14 EPX72360.1 - 3.1e-40 137.1 5.2 3.7e-40 136.9 3.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family NAC PF01849.13 EPX72361.1 - 9.5e-16 57.0 1.5 2.8e-15 55.5 0.3 2.1 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EPX72361.1 - 0.001 18.8 1.4 0.001 18.8 1.0 1.7 2 0 0 2 2 2 1 UBA/TS-N domain ESX-1_EspG PF14011.1 EPX72361.1 - 0.16 11.1 3.0 0.2 10.8 2.1 1.1 1 0 0 1 1 1 0 EspG family YIF1 PF03878.10 EPX72362.1 - 7.2e-95 316.6 3.2 8.3e-95 316.4 2.2 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EPX72362.1 - 0.00024 20.6 4.2 0.00046 19.7 2.9 1.5 1 1 0 1 1 1 1 Yip1 domain eIF-1a PF01176.14 EPX72363.1 - 2.7e-27 93.9 0.2 3.9e-27 93.4 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 CorA PF01544.13 EPX72364.1 - 1.9e-09 36.9 6.1 5.8e-09 35.3 4.2 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein NTPase_1 PF03266.10 EPX72364.1 - 0.082 12.6 0.0 1.2 8.8 0.0 2.2 1 1 1 2 2 2 0 NTPase PRD PF00874.15 EPX72364.1 - 0.097 12.8 0.2 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 PRD domain ATP1G1_PLM_MAT8 PF02038.11 EPX72364.1 - 0.15 11.0 0.6 0.43 9.6 0.1 2.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF1690 PF07956.6 EPX72365.1 - 1.8e-35 122.0 7.1 2e-35 121.8 4.9 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Alpha-E PF04168.7 EPX72365.1 - 0.017 14.4 3.3 0.042 13.2 1.7 1.7 1 1 1 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. CHCH PF06747.8 EPX72365.1 - 0.042 13.7 1.2 0.086 12.7 0.1 2.0 2 0 0 2 2 2 0 CHCH domain VitD-bind_III PF09164.5 EPX72365.1 - 0.14 11.7 1.2 0.21 11.2 0.2 1.8 2 1 0 2 2 2 0 Vitamin D binding protein, domain III Phasin PF05597.6 EPX72365.1 - 0.18 11.5 5.5 0.31 10.8 0.8 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) eIF3_N PF09440.5 EPX72365.1 - 0.35 11.0 4.8 0.33 11.1 2.2 1.7 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain IncA PF04156.9 EPX72365.1 - 0.38 10.3 5.1 0.43 10.1 3.6 1.2 1 0 0 1 1 1 0 IncA protein OmpH PF03938.9 EPX72365.1 - 0.88 9.4 5.4 1.2 9.0 3.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) THUMP PF02926.12 EPX72366.1 - 8.7e-21 74.3 2.1 9e-21 74.2 0.6 1.6 1 1 1 2 2 2 1 THUMP domain Bromodomain PF00439.20 EPX72367.1 - 1.5e-18 66.4 0.1 4.3e-18 65.0 0.1 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EPX72367.1 - 1.1e-14 53.8 0.0 2.2e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Neur_chan_memb PF02932.11 EPX72367.1 - 5.3 6.8 12.0 0.65 9.8 4.0 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Cpn60_TCP1 PF00118.19 EPX72368.1 - 2.1e-143 478.4 0.5 2.5e-143 478.2 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1744 PF08490.7 EPX72369.1 - 1.5e-137 458.3 5.3 2.3e-137 457.8 3.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EPX72369.1 - 1.5e-68 231.0 1.2 1.5e-68 231.0 0.9 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EPX72369.1 - 2.6e-24 85.8 0.1 1.1e-23 83.8 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EPX72369.1 - 2e-10 40.5 0.1 7.6e-10 38.6 0.1 2.0 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EPX72369.1 - 9.9e-05 22.2 0.3 0.0008 19.2 0.2 2.7 1 1 0 1 1 1 1 RNase_H superfamily zf-DNA_Pol PF08996.5 EPX72369.1 - 0.031 13.6 1.2 0.084 12.2 0.8 1.7 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DUF3767 PF12597.3 EPX72370.1 - 4.1e-22 78.0 0.0 4.4e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3265 PF11665.3 EPX72370.1 - 0.3 10.9 2.0 0.47 10.3 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3265) UNC-50 PF05216.8 EPX72371.1 - 9.6e-78 260.5 17.5 1.1e-77 260.3 12.1 1.0 1 0 0 1 1 1 1 UNC-50 family DUF1282 PF06930.7 EPX72371.1 - 0.0064 16.1 13.5 0.012 15.3 9.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1282) DUF912 PF06024.7 EPX72371.1 - 7.3 6.7 8.3 6.9 6.7 1.3 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PDCD2_C PF04194.8 EPX72372.1 - 2.7e-37 127.8 0.7 1.6e-36 125.3 0.0 2.1 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain DUF3039 PF11238.3 EPX72372.1 - 0.025 14.0 0.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) YdjO PF14169.1 EPX72372.1 - 0.042 13.3 1.0 2.3 7.7 0.1 2.9 2 0 0 2 2 2 0 Cold-inducible protein YdjO Fer4_8 PF13183.1 EPX72372.1 - 6.2 6.9 9.1 39 4.3 3.4 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain VHS PF00790.14 EPX72373.1 - 3.3e-48 162.8 0.0 1.2e-47 161.0 0.0 2.0 3 0 0 3 3 3 1 VHS domain Alpha_adaptinC2 PF02883.15 EPX72373.1 - 3.6e-14 53.0 2.0 3.6e-14 53.0 1.4 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.9 EPX72373.1 - 5.7e-06 26.2 0.4 5.7e-06 26.2 0.3 2.4 3 0 0 3 3 3 1 GAT domain Ribosomal_S4e PF00900.15 EPX72374.1 - 9.7e-34 114.8 0.7 1.8e-33 113.9 0.5 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EPX72374.1 - 8.9e-19 67.0 6.4 1.9e-18 65.9 4.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EPX72374.1 - 2.2e-06 27.0 0.0 5.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EPX72374.1 - 0.00074 19.1 0.4 0.00074 19.1 0.3 2.7 3 0 0 3 3 3 1 KOW motif Pkinase PF00069.20 EPX72375.1 - 3.5e-68 229.5 0.0 4.1e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72375.1 - 1.1e-28 100.0 0.0 2.1e-28 99.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX72375.1 - 6.5e-05 22.0 0.0 0.00028 19.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EPX72375.1 - 0.047 12.5 0.1 0.079 11.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EPX72375.1 - 0.052 13.2 0.2 0.092 12.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease PF00324.16 EPX72376.1 - 1.9e-124 415.6 42.1 2.2e-124 415.4 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPX72376.1 - 1.3e-38 132.6 44.2 1.6e-38 132.3 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3584 PF12128.3 EPX72377.1 - 0.0049 14.2 2.2 0.0059 14.0 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Baculo_PEP_N PF04512.7 EPX72377.1 - 0.019 14.9 0.1 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, N terminus SNase PF00565.12 EPX72378.1 - 2.3e-26 92.1 0.0 3.2e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ANTH PF07651.11 EPX72379.1 - 8.1e-67 224.8 0.2 1.1e-66 224.3 0.2 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EPX72379.1 - 2.4e-08 33.8 0.4 6e-08 32.5 0.1 1.8 2 0 0 2 2 2 1 ENTH domain Septin PF00735.13 EPX72380.1 - 9.2e-80 267.6 0.3 1.3e-79 267.1 0.2 1.2 1 0 0 1 1 1 1 Septin Pkinase PF00069.20 EPX72381.1 - 4.7e-71 238.9 0.0 1.6e-70 237.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72381.1 - 3.5e-50 170.4 0.0 6.5e-50 169.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX72381.1 - 0.0031 16.5 0.0 0.0068 15.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like ABC1 PF03109.11 EPX72381.1 - 0.022 14.7 0.0 0.093 12.6 0.0 2.0 2 0 0 2 2 2 0 ABC1 family Arm PF00514.18 EPX72381.1 - 0.032 14.0 1.6 5.8 6.8 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Med8 PF10232.4 EPX72382.1 - 2.1e-46 158.2 6.7 2.8e-46 157.8 4.6 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF563 PF04577.9 EPX72382.1 - 0.26 11.1 1.3 0.44 10.4 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF563) Kelch_3 PF13415.1 EPX72383.1 - 2.9e-18 65.4 3.5 6.5e-10 38.8 0.1 4.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EPX72383.1 - 1.4e-17 63.0 4.6 7.1e-06 25.9 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EPX72383.1 - 9e-17 60.5 2.9 1.2e-07 31.3 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EPX72383.1 - 2.5e-12 46.1 2.6 0.0044 16.5 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.1 EPX72383.1 - 1.7e-11 43.8 8.7 0.00064 19.6 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EPX72383.1 - 9.9e-11 40.9 4.7 0.0058 16.3 0.1 4.6 4 0 0 4 4 4 3 Kelch motif TLD PF07534.11 EPX72384.1 - 1.6e-23 83.1 0.8 8.9e-22 77.5 0.5 2.3 1 1 0 1 1 1 1 TLD EVE PF01878.13 EPX72385.1 - 2.6e-38 131.2 0.1 2.6e-38 131.2 0.0 1.9 2 1 1 3 3 3 1 EVE domain AT_hook PF02178.14 EPX72386.1 - 0.099 12.3 1.7 0.31 10.8 1.2 1.9 1 0 0 1 1 1 0 AT hook motif CENP-H PF05837.7 EPX72386.1 - 0.43 10.7 4.3 10 6.3 1.7 2.9 2 1 0 2 2 2 0 Centromere protein H (CENP-H) MAT1 PF06391.8 EPX72387.1 - 7.6e-59 198.6 20.0 1e-58 198.2 13.9 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EPX72387.1 - 0.00022 20.8 4.2 0.0011 18.5 0.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EPX72387.1 - 0.045 13.3 7.8 0.23 11.0 1.6 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EPX72387.1 - 0.082 12.9 9.6 0.59 10.2 6.8 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3797 PF12677.2 EPX72387.1 - 0.094 12.3 1.4 0.21 11.2 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-C3HC4_3 PF13920.1 EPX72387.1 - 0.13 12.0 9.0 0.91 9.2 6.0 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX72387.1 - 0.13 12.0 8.6 0.99 9.1 6.1 2.2 1 1 1 2 2 2 0 zinc-RING finger domain RED_C PF07807.6 EPX72387.1 - 0.73 10.0 4.4 0.57 10.3 1.6 1.9 1 1 1 2 2 2 0 RED-like protein C-terminal region zf-RING_2 PF13639.1 EPX72387.1 - 0.84 9.5 14.4 0.13 12.1 5.8 2.4 2 1 1 3 3 3 0 Ring finger domain RRP7 PF12923.2 EPX72388.1 - 3e-31 108.1 8.4 4.3e-31 107.6 5.8 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) IncA PF04156.9 EPX72388.1 - 0.44 10.1 6.2 0.32 10.5 0.3 2.1 2 0 0 2 2 2 0 IncA protein DUF3671 PF12420.3 EPX72390.1 - 8.2 6.4 9.0 1.3 9.0 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function 2-oxoacid_dh PF00198.18 EPX72391.1 - 4.7e-75 251.8 0.0 5.9e-75 251.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EPX72391.1 - 1.2e-17 63.3 0.1 2.1e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EPX72391.1 - 8.9e-05 22.0 0.3 0.058 13.0 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_2 PF12700.2 EPX72391.1 - 0.0055 15.9 0.0 0.24 10.5 0.0 2.3 2 1 1 3 3 3 1 HlyD family secretion protein RnfC_N PF13375.1 EPX72391.1 - 0.012 15.3 0.0 0.29 10.8 0.0 2.4 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 EPX72391.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_3 PF13437.1 EPX72391.1 - 0.033 14.5 0.2 4 7.8 0.0 2.4 2 0 0 2 2 2 0 HlyD family secretion protein LCAT PF02450.10 EPX72392.1 - 5.6e-129 430.5 0.0 6.8e-129 430.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EPX72392.1 - 0.00071 18.9 0.1 0.0031 16.8 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 2) DUF900 PF05990.7 EPX72392.1 - 0.13 11.5 0.0 0.44 9.8 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Cnd1 PF12717.2 EPX72393.1 - 9.4e-53 178.6 2.2 2.8e-48 164.1 0.7 3.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EPX72393.1 - 8.7e-33 113.3 4.1 8.7e-33 113.3 2.8 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EPX72393.1 - 3e-09 37.0 0.1 0.0089 16.2 0.0 4.2 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.17 EPX72393.1 - 1.1e-06 28.1 1.1 1.3 9.2 0.0 4.9 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 EPX72393.1 - 0.004 17.6 0.1 18 5.9 0.0 4.6 3 1 1 4 4 4 1 HEAT-like repeat Pkinase PF00069.20 EPX72394.1 - 5e-42 143.8 0.0 5.8e-38 130.5 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72394.1 - 2.3e-11 43.2 0.7 1.5e-06 27.4 0.0 4.0 4 1 0 4 4 4 2 Protein tyrosine kinase APH PF01636.18 EPX72394.1 - 0.00033 20.4 0.0 0.0011 18.7 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family YbjM PF11045.3 EPX72394.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae Ribosomal_L18e PF00828.14 EPX72395.1 - 6.8e-35 120.2 0.1 8.3e-35 119.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Lyase_8_N PF08124.6 EPX72395.1 - 0.084 11.7 0.0 0.091 11.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain GFA PF04828.9 EPX72396.1 - 1e-11 44.6 2.3 1.6e-11 43.9 1.6 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-CHY PF05495.7 EPX72397.1 - 6.8e-16 58.1 12.0 9.3e-16 57.7 8.3 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-RING_4 PF14570.1 EPX72397.1 - 0.0092 15.5 1.9 0.0092 15.5 1.3 3.3 3 1 0 3 3 3 1 RING/Ubox like zinc-binding domain C1_1 PF00130.17 EPX72397.1 - 0.042 13.5 1.6 0.042 13.5 1.1 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Tmemb_55A PF09788.4 EPX72397.1 - 0.13 11.3 6.2 0.16 11.0 4.3 1.3 1 1 0 1 1 1 0 Transmembrane protein 55A DZR PF12773.2 EPX72397.1 - 0.31 10.8 15.8 1.1e+02 2.7 11.0 2.9 1 1 0 1 1 1 0 Double zinc ribbon zf-CHC2 PF01807.15 EPX72397.1 - 0.44 10.1 3.0 0.9 9.1 2.1 1.5 1 0 0 1 1 1 0 CHC2 zinc finger Cytochrome_C7 PF14522.1 EPX72397.1 - 0.92 9.1 13.2 3.4 7.3 9.1 2.0 1 1 0 1 1 1 0 Cytochrome c7 Lar_restr_allev PF14354.1 EPX72397.1 - 4.6 7.6 8.4 91 3.4 5.8 2.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-C3HC4_3 PF13920.1 EPX72397.1 - 5.1 6.8 18.5 0.048 13.3 2.3 2.7 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WCCH PF03716.9 EPX72397.1 - 5.8 6.4 10.4 1.5 8.3 0.5 2.8 2 0 0 2 2 2 0 WCCH motif DUF1451 PF07295.6 EPX72397.1 - 6.3 6.5 8.4 1 9.1 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) COG6 PF06419.6 EPX72398.1 - 8e-123 410.7 20.0 9.7e-123 410.4 13.8 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Seryl_tRNA_N PF02403.17 EPX72398.1 - 1 9.4 5.2 0.43 10.6 0.2 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BCDHK_Adom3 PF10436.4 EPX72398.1 - 1 8.8 6.7 2.1 7.8 0.1 3.7 2 2 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DEAD PF00270.24 EPX72399.1 - 7.6e-40 136.1 0.0 1.1e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX72399.1 - 4.8e-23 80.8 0.1 8.4e-23 80.0 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Flavi_DEAD PF07652.9 EPX72399.1 - 0.12 12.1 0.7 0.27 10.9 0.1 1.7 2 0 0 2 2 2 0 Flavivirus DEAD domain DUF2763 PF10961.3 EPX72399.1 - 4.4 7.7 6.0 8.2 6.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Nrap PF03813.9 EPX72400.1 - 2e-277 922.6 1.4 2.5e-277 922.3 1.0 1.0 1 0 0 1 1 1 1 Nrap protein DUF1806 PF08830.5 EPX72400.1 - 0.077 12.8 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1806) MAM33 PF02330.11 EPX72401.1 - 3.3e-55 187.0 4.0 3.8e-55 186.8 2.8 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein AdoMetDC_leader PF08132.6 EPX72401.1 - 0.11 12.4 0.0 18 5.3 0.0 2.5 2 0 0 2 2 2 0 S-adenosyl-l-methionine decarboxylase leader peptide SPA PF08616.5 EPX72402.1 - 4.1e-32 110.2 0.1 4.7e-31 106.8 0.0 2.4 1 1 1 2 2 2 1 Stabilization of polarity axis Afi1 PF07792.7 EPX72402.1 - 5.7e-24 84.7 0.0 1.3e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2347 PF09804.4 EPX72402.1 - 8.3e-10 38.4 0.6 1.1e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 EPX72402.1 - 1.6e-05 23.5 11.9 0.00034 19.1 0.1 3.6 3 1 1 4 4 4 3 Transport protein Avl9 Kisspeptin PF15152.1 EPX72402.1 - 0.17 12.6 0.5 15 6.3 0.1 2.5 2 0 0 2 2 2 0 Kisspeptin DENN PF02141.16 EPX72402.1 - 0.34 10.6 4.7 0.43 10.2 0.3 2.8 3 0 0 3 3 3 0 DENN (AEX-3) domain DUF2838 PF10998.3 EPX72403.1 - 3.5e-38 129.8 10.4 3.5e-38 129.8 7.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Sec23_trunk PF04811.10 EPX72404.1 - 4.4e-69 232.5 0.0 6.4e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPX72404.1 - 8.2e-31 105.4 0.2 1.6e-30 104.5 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPX72404.1 - 3.8e-29 101.0 0.2 8.7e-29 99.8 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EPX72404.1 - 1.1e-15 56.8 8.7 2.4e-15 55.8 6.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EPX72404.1 - 2.4e-11 43.1 0.0 5.4e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Homoserine_dh PF00742.14 EPX72405.1 - 2.6e-51 173.8 0.0 3.9e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EPX72405.1 - 4e-16 59.4 0.0 1.3e-15 57.7 0.0 1.9 2 1 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPX72405.1 - 0.081 12.0 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Metallophos PF00149.23 EPX72406.1 - 1.4e-43 148.6 0.9 1.7e-43 148.3 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L29e PF01779.12 EPX72407.1 - 2.1e-22 78.7 14.7 2.9e-22 78.2 10.2 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family SSrecog PF03531.9 EPX72408.1 - 1.7e-98 328.3 0.0 2.4e-98 327.8 0.0 1.2 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EPX72408.1 - 3.9e-28 97.2 0.0 1.4e-24 85.8 0.0 2.7 3 0 0 3 3 3 2 Histone chaperone Rttp106-like DUF3671 PF12420.3 EPX72410.1 - 0.014 15.3 0.3 0.019 14.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function Phospholamban PF04272.9 EPX72410.1 - 0.062 12.7 5.0 0.1 12.0 3.5 1.4 1 0 0 1 1 1 0 Phospholamban DUF2663 PF10864.3 EPX72410.1 - 0.13 12.5 0.1 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) WD40 PF00400.27 EPX72411.1 - 8.3e-24 82.5 8.8 8.1e-06 25.5 0.0 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat DSPc PF00782.15 EPX72412.1 - 6.9e-07 28.9 0.3 1.9e-06 27.4 0.2 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EPX72412.1 - 0.00036 20.8 0.1 0.00057 20.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EPX72412.1 - 0.00059 19.2 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EPX72412.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate RNB PF00773.14 EPX72413.1 - 2.2e-46 158.6 0.2 6e-46 157.2 0.1 1.8 1 0 0 1 1 1 1 RNB domain CAT PF00302.13 EPX72413.1 - 0.07 12.7 0.4 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol acetyltransferase Ribosomal_L36e PF01158.13 EPX72414.1 - 7.3e-40 134.9 3.9 7.9e-40 134.8 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EPX72414.1 - 0.02 13.9 0.1 0.021 13.9 0.1 1.1 1 0 0 1 1 1 0 LemA family TetR_C_9 PF14514.1 EPX72414.1 - 0.057 13.2 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator, TetR, C-terminal DnaJ PF00226.26 EPX72415.1 - 3.8e-21 74.5 0.8 6.4e-21 73.8 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EPX72415.1 - 7.7e-19 67.3 0.0 3e-17 62.2 0.0 2.6 2 1 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EPX72415.1 - 1.7e-12 47.1 16.6 3.1e-12 46.3 11.5 1.4 1 0 0 1 1 1 1 DnaJ central domain UPF0547 PF10571.4 EPX72415.1 - 0.14 11.8 6.2 1.3 8.7 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 HypA PF01155.14 EPX72415.1 - 0.39 10.4 4.5 2 8.1 0.6 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 EPX72415.1 - 1.1 9.6 9.5 1.9 8.8 6.6 1.4 1 0 0 1 1 1 0 Cytochrome c3 ATG16 PF08614.6 EPX72416.1 - 4.1e-09 36.5 11.4 8.3e-05 22.4 4.1 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF641 PF04859.7 EPX72416.1 - 0.23 11.1 3.7 0.41 10.4 2.5 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) IncA PF04156.9 EPX72416.1 - 0.24 10.9 6.7 0.29 10.7 4.7 1.2 1 0 0 1 1 1 0 IncA protein Ras PF00071.17 EPX72417.1 - 5.8e-58 194.8 0.3 6.8e-58 194.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX72417.1 - 9.2e-19 68.0 0.1 1.9e-18 67.1 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EPX72417.1 - 1.4e-12 47.2 0.0 1.6e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPX72417.1 - 1.6e-08 33.9 0.0 2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPX72417.1 - 3.8e-07 30.0 0.0 5.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPX72417.1 - 7.2e-07 28.8 0.0 5.7e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EPX72417.1 - 7.4e-05 22.3 0.5 0.0019 17.8 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EPX72417.1 - 0.00033 20.7 0.0 0.0011 19.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 EPX72417.1 - 0.0022 17.1 0.1 0.0051 16.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EPX72417.1 - 0.0043 16.2 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.13 EPX72417.1 - 0.01 14.8 0.1 0.034 13.1 0.0 1.8 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 EPX72417.1 - 0.012 15.3 0.6 0.017 14.8 0.1 1.5 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 EPX72417.1 - 0.012 15.0 0.1 0.45 10.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EPX72417.1 - 0.014 15.3 0.0 0.044 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 EPX72417.1 - 0.022 14.3 0.2 0.048 13.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EPX72417.1 - 0.026 13.9 0.1 0.075 12.4 0.1 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 EPX72417.1 - 0.034 12.8 0.1 0.58 8.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.10 EPX72417.1 - 0.039 13.6 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_10 PF12846.2 EPX72417.1 - 0.039 13.3 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 EPX72417.1 - 0.045 13.9 0.1 0.36 11.0 0.0 2.2 2 1 0 2 2 2 0 RNA helicase MobB PF03205.9 EPX72417.1 - 0.051 13.2 0.5 0.091 12.4 0.1 1.8 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EPX72417.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EPX72417.1 - 0.092 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 EPX72417.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPX72417.1 - 0.19 12.0 0.6 0.27 11.5 0.4 1.7 1 1 0 1 1 1 0 ABC transporter TPT PF03151.11 EPX72418.1 - 3.1e-08 33.3 28.2 4.9e-06 26.2 5.2 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EPX72418.1 - 7.8e-07 29.2 29.1 3.2e-05 24.1 1.2 3.5 3 2 0 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 EPX72418.1 - 9.6e-07 28.8 39.7 0.00076 19.5 5.7 3.2 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EPX72418.1 - 3.4e-05 22.8 16.5 5.4e-05 22.1 11.5 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EPX72418.1 - 0.0019 17.1 19.6 0.0048 15.8 13.6 1.7 1 1 0 1 1 1 1 UAA transporter family GARS_A PF01071.14 EPX72420.1 - 1.5e-80 269.3 0.0 4.4e-80 267.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.17 EPX72420.1 - 9.6e-35 119.8 0.0 1.8e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.10 EPX72420.1 - 2.8e-32 111.1 0.3 7.7e-31 106.5 0.0 3.3 4 0 0 4 4 3 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 EPX72420.1 - 4.8e-29 100.3 0.0 9.9e-29 99.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EPX72420.1 - 5.8e-17 61.7 0.4 1.8e-16 60.1 0.3 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EPX72420.1 - 8.3e-08 32.1 0.0 4.3e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPX72420.1 - 4.4e-05 22.3 0.0 8.7e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EPX72420.1 - 8.1e-05 21.9 0.0 0.00016 20.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 EPX72420.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EPX72420.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.5 EPX72420.1 - 0.021 14.2 0.0 0.051 12.9 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain GHMP_kinases_N PF00288.21 EPX72421.1 - 1.4e-12 47.4 0.0 2.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPX72421.1 - 0.0057 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Mss4 PF04421.8 EPX72422.1 - 2.1e-21 75.5 0.0 2.3e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Mss4 protein Fork_head PF00250.13 EPX72423.1 - 1.3e-35 121.3 0.3 2.6e-35 120.3 0.2 1.5 1 0 0 1 1 1 1 Fork head domain RNA_pol_Rpb1_5 PF04998.12 EPX72424.1 - 2.9e-98 328.5 0.2 6.2e-98 327.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EPX72424.1 - 3.7e-63 212.3 0.1 1.2e-62 210.7 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EPX72424.1 - 3.9e-37 127.4 0.0 9.5e-37 126.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EPX72424.1 - 2.9e-25 89.2 14.1 3.8e-24 85.5 1.6 4.1 2 2 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EPX72424.1 - 5.8e-23 80.6 0.5 2.8e-22 78.4 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Asn_synthase PF00733.16 EPX72424.1 - 0.0068 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase muHD PF10291.4 EPX72425.1 - 3e-22 79.0 0.2 1.1e-21 77.2 0.0 1.9 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EPX72425.1 - 9.6e-11 41.7 2.4 9.6e-11 41.7 1.7 3.1 2 1 1 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain JAB PF01398.16 EPX72426.1 - 8.9e-21 73.7 0.0 1.6e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EPX72426.1 - 2.2e-15 56.7 0.0 3.4e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Glyco_transf_8 PF01501.15 EPX72427.1 - 6.4e-13 48.6 2.8 1.5e-12 47.3 2.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_8 PF01501.15 EPX72428.1 - 2.8e-11 43.2 3.5 6.2e-11 42.0 2.5 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EPX72428.1 - 0.0013 18.1 0.1 0.0021 17.4 0.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Proteasome PF00227.21 EPX72429.1 - 1.3e-49 168.0 1.0 1.5e-49 167.8 0.7 1.0 1 0 0 1 1 1 1 Proteasome subunit Transposase_21 PF02992.9 EPX72429.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Transposase family tnp2 Pkinase PF00069.20 EPX72430.1 - 1e-60 205.1 0.0 1.3e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72430.1 - 2.5e-33 115.2 0.0 3.3e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX72430.1 - 0.002 17.8 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPX72430.1 - 0.0042 16.0 0.0 0.019 13.9 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPX72430.1 - 0.0044 16.1 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 EPX72430.1 - 0.0073 14.9 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC RIO1 PF01163.17 EPX72430.1 - 0.0083 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family RabGAP-TBC PF00566.13 EPX72431.1 - 1.5e-34 119.3 0.3 3.1e-34 118.3 0.2 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain U-box PF04564.10 EPX72431.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 U-box domain P21-Arc PF04062.9 EPX72432.1 - 1.7e-80 268.9 0.0 1.9e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit N2227 PF07942.7 EPX72433.1 - 9.7e-108 359.2 0.4 1.4e-107 358.7 0.3 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EPX72433.1 - 1.1e-05 25.2 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CH PF00307.26 EPX72434.1 - 3.7e-68 226.4 0.1 2.2e-18 66.2 0.3 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EPX72434.1 - 9.6e-11 41.1 0.0 0.026 14.1 0.0 4.3 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_1 PF00036.27 EPX72434.1 - 4e-08 32.0 1.3 0.0016 17.5 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EPX72434.1 - 4.4e-07 29.9 1.3 1.3e-06 28.4 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EPX72434.1 - 0.00061 19.4 2.2 1.2 9.2 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EPX72434.1 - 0.0021 17.6 1.0 1.1 8.8 0.1 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPX72434.1 - 0.098 12.0 2.8 7.5 6.0 0.1 3.2 3 0 0 3 3 3 0 EF hand Dfp1_Him1_M PF08630.5 EPX72436.1 - 3.2e-30 104.4 0.0 6.6e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EPX72436.1 - 3.4e-18 65.0 1.9 7e-18 64.0 1.3 1.6 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EPX72436.1 - 1.6e-06 28.1 0.1 2.9e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-C2H2_2 PF12756.2 EPX72436.1 - 0.054 13.6 0.2 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PTCB-BRCT PF12738.2 EPX72436.1 - 0.079 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain NUDIX PF00293.23 EPX72437.1 - 9.4e-15 54.4 0.0 6e-14 51.8 0.0 2.1 2 1 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.6 EPX72437.1 - 2.5e-14 53.3 0.0 4.6e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EPX72437.1 - 1.9e-06 27.2 1.3 3.8e-06 26.3 0.9 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Rap1-DNA-bind PF09197.5 EPX72438.1 - 2.9e-05 24.5 0.4 0.00061 20.2 0.0 2.9 2 1 0 2 2 2 1 Rap1, DNA-binding DUF3095 PF11294.3 EPX72438.1 - 0.11 11.5 0.1 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) DnaJ PF00226.26 EPX72439.1 - 3.6e-19 68.2 2.5 1.1e-18 66.7 1.7 1.9 1 0 0 1 1 1 1 DnaJ domain DUF2803 PF10972.3 EPX72439.1 - 8.7 5.7 10.9 5.3 6.4 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2803) CBFD_NFYB_HMF PF00808.18 EPX72440.1 - 5.6e-20 71.1 1.0 5.6e-20 71.1 0.7 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPX72440.1 - 0.00097 19.2 0.3 0.0022 18.0 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EPX72440.1 - 0.32 10.8 2.0 1.1 9.1 0.8 2.3 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit DUF853 PF05872.7 EPX72440.1 - 0.48 8.6 3.3 0.6 8.3 2.3 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF3510 PF12022.3 EPX72440.1 - 0.9 9.6 4.8 0.58 10.2 1.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) ING PF12998.2 EPX72440.1 - 3.3 8.0 7.8 11 6.4 3.3 2.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ISN1 PF06437.6 EPX72441.1 - 1e-163 544.8 0.0 1.2e-163 544.6 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Swi3 PF07962.7 EPX72442.1 - 6.6e-28 96.1 0.1 9.4e-28 95.6 0.0 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Complex1_LYR PF05347.10 EPX72443.1 - 0.00035 20.2 0.5 0.00059 19.5 0.0 1.7 2 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPX72443.1 - 0.0019 18.3 0.0 0.0027 17.8 0.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like LSM PF01423.17 EPX72444.1 - 4.7e-16 58.0 0.0 6.8e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain DUF3602 PF12223.3 EPX72444.1 - 0.028 14.7 2.1 0.048 14.0 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) SM-ATX PF14438.1 EPX72444.1 - 0.057 13.3 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_N PF09825.4 EPX72445.1 - 5.6e-86 288.6 0.0 7.4e-86 288.2 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EPX72445.1 - 2.5e-26 92.1 0.0 4.5e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EPX72445.1 - 0.00099 18.7 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Mgm101p PF06420.7 EPX72446.1 - 3.1e-92 306.5 0.0 3.8e-92 306.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 TB2_DP1_HVA22 PF03134.14 EPX72447.1 - 3.8e-21 74.6 3.2 3.2e-20 71.6 2.2 2.0 1 1 0 1 1 1 1 TB2/DP1, HVA22 family T_hemolysin PF12261.3 EPX72447.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.7 1 1 1 2 2 2 0 Thermostable hemolysin EOS1 PF12326.3 EPX72447.1 - 8 6.0 7.0 14 5.2 0.3 2.3 1 1 1 2 2 2 0 N-glycosylation protein FAT PF02259.18 EPX72448.1 - 2.4e-107 358.9 1.3 2.4e-107 358.9 0.9 2.4 2 1 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EPX72448.1 - 5.9e-59 199.3 0.8 1.2e-58 198.4 0.6 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EPX72448.1 - 1.9e-43 148.1 2.6 1.9e-43 148.1 1.8 3.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EPX72448.1 - 3.2e-38 129.8 0.6 3.2e-38 129.8 0.4 3.4 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EPX72448.1 - 1.1e-18 67.2 2.2 0.0043 17.2 0.0 9.0 5 1 3 9 9 9 4 HEAT repeats FATC PF02260.15 EPX72448.1 - 4.7e-16 57.9 0.1 1e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EPX72448.1 - 3.5e-14 51.5 12.2 0.028 14.4 0.0 10.9 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 EPX72448.1 - 1.2e-06 28.8 19.3 0.072 13.5 0.0 9.9 10 1 2 12 12 12 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPX72448.1 - 0.0018 18.6 2.7 12 6.3 0.0 6.0 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 EPX72448.1 - 0.0065 16.3 1.8 57 3.8 0.0 5.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Gpi1 PF05024.10 EPX72449.1 - 9.8e-67 224.2 17.4 2e-66 223.2 12.1 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MRP-S33 PF08293.6 EPX72450.1 - 1.6e-18 66.4 0.2 1.9e-18 66.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Transket_pyr PF02779.19 EPX72451.1 - 2e-47 160.9 0.1 3.5e-46 156.9 0.0 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EPX72451.1 - 1.3e-35 122.0 0.1 2.7e-35 121.0 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DLH PF01738.13 EPX72452.1 - 4.4e-17 62.0 0.0 5e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPX72452.1 - 7.4e-08 32.2 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Gar1 PF04410.9 EPX72453.1 - 2.9e-44 150.2 0.4 2.9e-44 150.2 0.3 2.0 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region MethyTransf_Reg PF10119.4 EPX72453.1 - 0.11 13.0 0.0 14 6.2 0.0 3.2 3 0 0 3 3 3 0 Predicted methyltransferase regulatory domain PDT PF00800.13 EPX72454.1 - 6.2e-58 195.3 0.0 8.2e-58 194.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase SMI1_KNR4 PF09346.5 EPX72455.1 - 7.4e-31 106.8 0.0 1.5e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Ribosomal_L1 PF00687.16 EPX72456.1 - 7.8e-50 169.2 1.1 9.3e-50 169.0 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Rhomboid PF01694.17 EPX72457.1 - 1.5e-20 73.6 15.0 1.5e-20 73.6 10.4 1.6 2 0 0 2 2 2 1 Rhomboid family TFIIB PF00382.14 EPX72458.1 - 1.3e-34 117.8 1.5 7.5e-18 64.1 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EPX72458.1 - 3.5e-26 91.2 7.1 3.5e-26 91.2 4.9 1.9 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EPX72458.1 - 2.1e-10 39.7 1.0 4.2e-10 38.7 0.7 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EPX72458.1 - 7.8e-06 25.4 3.3 0.012 15.1 0.1 2.7 3 0 0 3 3 3 2 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 EPX72458.1 - 0.48 9.6 3.4 1.2 8.4 2.4 1.7 1 1 0 1 1 1 0 zinc-ribbon domain RRN7 PF11781.3 EPX72458.1 - 0.79 9.2 3.9 0.43 10.1 0.6 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 WH2 PF02205.15 EPX72459.1 - 2.7e-12 45.8 2.2 1.3e-10 40.5 0.9 2.4 2 0 0 2 2 2 2 WH2 motif Leo1 PF04004.8 EPX72460.1 - 1.1e-37 129.3 0.2 1.1e-37 129.3 0.1 2.5 3 0 0 3 3 3 1 Leo1-like protein DUF106 PF01956.11 EPX72461.1 - 1.2 8.6 12.0 2.1 7.8 1.9 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF106 AIF-MLS PF14962.1 EPX72461.1 - 2.7 7.6 13.9 0.026 14.1 3.6 2.0 2 1 1 3 3 3 0 Mitochondria Localisation Sequence DUF4124 PF13511.1 EPX72461.1 - 2.7 8.1 4.9 2.4 8.2 0.2 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4124) RNA_pol_Rpb1_5 PF04998.12 EPX72461.1 - 8.6 5.5 15.4 58 2.8 10.7 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 ADIP PF11559.3 EPX72462.1 - 1.5e-10 41.1 23.5 1.5e-10 41.1 16.3 2.5 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding DUF4525 PF15027.1 EPX72462.1 - 0.6 9.6 5.1 0.6 9.6 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4525) Med4 PF10018.4 EPX72462.1 - 1.6 8.1 14.9 0.14 11.5 4.9 2.8 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Mannosyl_trans PF05007.8 EPX72463.1 - 2.9e-90 302.4 23.7 2.9e-90 302.4 16.4 2.2 3 1 0 3 3 3 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EPX72463.1 - 6.9e-07 28.4 26.7 6.9e-07 28.4 18.5 3.4 2 2 1 3 3 3 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EPX72463.1 - 1.8e-06 27.6 4.4 1.8e-06 27.6 3.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2029) ATP-synt_DE_N PF02823.11 EPX72464.1 - 1.2e-19 69.8 0.0 1.8e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain SAM_2 PF07647.12 EPX72465.1 - 6.8e-14 51.4 0.3 4.1e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EPX72465.1 - 1.2e-07 31.7 0.0 2.7e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Acetyltransf_1 PF00583.19 EPX72466.1 - 5.4e-13 48.7 0.0 9.5e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPX72466.1 - 4.9e-08 33.0 0.0 9.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-CCCH PF00642.19 EPX72466.1 - 5.7e-08 32.2 2.0 1.2e-07 31.2 1.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Acetyltransf_7 PF13508.1 EPX72466.1 - 7.2e-08 32.4 0.1 2.7e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain zf-C3HC4_2 PF13923.1 EPX72466.1 - 7.8e-07 29.0 12.5 1.5e-06 28.1 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX72466.1 - 5.5e-06 25.9 7.9 1.1e-05 25.0 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX72466.1 - 0.0012 18.4 13.0 0.0023 17.5 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX72466.1 - 0.0025 17.4 10.7 0.0051 16.5 7.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPX72466.1 - 0.0027 17.4 9.9 0.0052 16.5 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain Acetyltransf_8 PF13523.1 EPX72466.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPX72466.1 - 0.11 12.3 0.1 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein zf-C3HC4_4 PF15227.1 EPX72466.1 - 0.45 10.4 9.3 1.2 9.0 6.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPX72466.1 - 0.95 9.2 8.7 1.1 9.0 4.1 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 EPX72466.1 - 3.7 7.1 8.4 3.1 7.3 4.7 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit MIF4G PF02854.14 EPX72467.1 - 3.7e-30 104.9 0.6 3.7e-30 104.9 0.4 1.9 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EPX72467.1 - 2.6e-26 91.5 0.1 5e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 MA3 domain Phtf-FEM1B_bdg PF12129.3 EPX72467.1 - 0.094 12.0 0.1 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Hydrolase_6 PF13344.1 EPX72468.1 - 3e-28 97.6 0.0 5.2e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPX72468.1 - 1.7e-13 50.0 0.0 3.4e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EPX72468.1 - 1.2e-12 48.7 0.0 3.1e-12 47.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EPX72468.1 - 1e-06 29.1 0.0 0.029 14.5 0.1 3.0 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EPX72468.1 - 0.0065 15.8 0.0 0.55 9.5 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase PNK3P PF08645.6 EPX72468.1 - 0.0087 15.5 0.0 3.3 7.1 0.0 2.3 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase WD40 PF00400.27 EPX72469.1 - 2.4e-54 179.4 12.6 1.3e-10 40.7 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EPX72469.1 - 1.5e-43 148.2 0.7 2.5e-43 147.5 0.5 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EPX72469.1 - 0.0026 15.9 0.5 0.24 9.5 0.1 3.2 1 1 2 3 3 3 1 Nucleoporin Nup120/160 LisH PF08513.6 EPX72469.1 - 0.0045 16.7 0.1 0.013 15.2 0.1 1.9 1 0 0 1 1 1 1 LisH DUF2415 PF10313.4 EPX72469.1 - 0.12 12.0 0.3 0.56 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) AKAP7_NLS PF10469.4 EPX72470.1 - 3.8e-29 101.8 0.0 4.7e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Hom_end_hint PF05203.11 EPX72471.1 - 0.034 13.8 0.6 0.038 13.7 0.4 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Nucleocapsid-N PF11030.3 EPX72471.1 - 0.069 12.9 2.0 0.083 12.6 1.4 1.2 1 0 0 1 1 1 0 Nucleocapsid protein N LIM_bind PF01803.11 EPX72471.1 - 0.16 11.0 2.8 0.18 10.8 2.0 1.3 1 0 0 1 1 1 0 LIM-domain binding protein Neugrin PF06413.6 EPX72471.1 - 0.19 11.5 2.4 0.23 11.2 1.6 1.2 1 0 0 1 1 1 0 Neugrin MAM33 PF02330.11 EPX72472.1 - 8.3e-10 38.7 1.0 9.7e-10 38.5 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tn7_Tnp_TnsA_C PF08721.6 EPX72472.1 - 0.027 14.4 0.1 0.088 12.8 0.1 1.9 1 0 0 1 1 1 0 TnsA endonuclease C terminal zf-CCCH PF00642.19 EPX72473.1 - 0.0021 17.7 1.6 0.0033 17.0 1.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4090 PF13319.1 EPX72473.1 - 0.2 11.6 0.0 1.5 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4090) DUF2141 PF09912.4 EPX72473.1 - 3.6 7.2 7.6 0.26 10.9 0.2 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) Cys_Met_Meta_PP PF01053.15 EPX72474.1 - 5.4e-34 117.1 0.0 8.5e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPX72474.1 - 0.039 12.9 0.1 0.15 11.0 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II Tropomyosin PF00261.15 EPX72475.1 - 0.0004 19.5 1.8 0.00044 19.4 1.3 1.1 1 0 0 1 1 1 1 Tropomyosin PP2C_C PF07830.8 EPX72475.1 - 0.0042 17.1 0.1 0.021 14.9 0.0 2.0 2 0 0 2 2 2 1 Protein serine/threonine phosphatase 2C, C-terminal domain Sigma70_ner PF04546.8 EPX72475.1 - 0.014 15.0 1.0 0.017 14.7 0.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DASH_Dad3 PF08656.5 EPX72475.1 - 0.17 11.5 1.4 1.5 8.6 0.4 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF848 PF05852.6 EPX72475.1 - 0.19 11.5 4.9 0.099 12.4 1.1 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) IncA PF04156.9 EPX72475.1 - 0.42 10.1 6.0 0.77 9.3 4.1 1.6 1 1 0 1 1 1 0 IncA protein APG9 PF04109.11 EPX72476.1 - 2.2e-140 467.8 7.9 3e-140 467.3 5.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Acetyltransf_1 PF00583.19 EPX72477.1 - 1.2e-16 60.4 0.1 2e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPX72477.1 - 1.3e-10 41.3 0.0 1.6e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPX72477.1 - 4.5e-10 39.1 0.1 6.6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EPX72477.1 - 1.4e-09 37.9 0.0 2.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPX72477.1 - 9.5e-08 32.0 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPX72477.1 - 5.7e-07 29.7 0.0 7.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPX72477.1 - 6.7e-05 22.7 0.0 9.4e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPX72477.1 - 0.00013 21.9 0.1 0.00016 21.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPX72477.1 - 0.017 14.9 2.1 0.017 14.9 0.0 2.0 2 1 0 2 2 2 0 GCN5-related N-acetyl-transferase cobW PF02492.14 EPX72478.1 - 3e-46 157.0 0.8 4.1e-46 156.6 0.5 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EPX72478.1 - 0.00028 20.5 0.0 0.00071 19.2 0.0 1.6 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.1 EPX72478.1 - 0.0044 17.0 0.0 0.0096 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain UPF0079 PF02367.12 EPX72478.1 - 0.012 15.2 0.1 0.031 13.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 EPX72478.1 - 0.014 14.1 0.4 2 7.1 0.0 2.8 3 0 0 3 3 3 0 ArgK protein Arch_ATPase PF01637.13 EPX72478.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 EPX72478.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EPX72478.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 EPX72478.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EPX72478.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Glycos_transf_4 PF00953.16 EPX72479.1 - 1.9e-32 112.3 12.0 5.1e-32 110.8 8.3 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 4 Hira PF07569.6 EPX72480.1 - 1.4e-68 230.3 0.8 8.2e-68 227.8 0.0 2.6 3 1 0 3 3 3 1 TUP1-like enhancer of split WD40 PF00400.27 EPX72480.1 - 4.9e-18 64.2 11.6 5e-07 29.3 0.1 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat SID-1_RNA_chan PF13965.1 EPX72480.1 - 0.044 11.9 0.2 0.072 11.2 0.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zn_clus PF00172.13 EPX72481.1 - 5.1e-09 35.8 10.9 1e-08 34.9 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.18 EPX72482.1 - 2.4e-69 233.5 0.0 6.1e-69 232.2 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain DUF2972 PF11186.3 EPX72482.1 - 0.12 12.2 4.5 0.3 10.9 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) FUSC PF04632.7 EPX72482.1 - 1.8 6.8 3.8 0.43 8.9 0.4 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Fib_alpha PF08702.5 EPX72482.1 - 4 7.5 13.5 0.86 9.7 1.1 3.1 3 1 0 4 4 4 0 Fibrinogen alpha/beta chain family UQ_con PF00179.21 EPX72483.1 - 5e-45 152.3 0.0 6.7e-45 151.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EPX72483.1 - 4.5e-07 29.3 0.1 6.7e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA PF00627.26 EPX72483.1 - 0.14 11.9 0.0 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 UBA/TS-N domain DUF1876 PF08962.6 EPX72483.1 - 0.17 11.7 0.1 0.39 10.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) ABC1 PF03109.11 EPX72485.1 - 2.1e-34 118.0 0.0 5.1e-34 116.7 0.0 1.7 1 0 0 1 1 1 1 ABC1 family Pept_tRNA_hydro PF01195.14 EPX72487.1 - 3.4e-31 108.1 0.0 4.3e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase CENP-S PF15630.1 EPX72488.1 - 2.1e-25 88.7 0.1 2.6e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EPX72488.1 - 2.6e-05 23.8 0.0 0.00031 20.4 0.0 2.1 2 0 0 2 2 2 1 Bromodomain associated CENP-T PF15511.1 EPX72488.1 - 0.0012 18.2 0.0 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Histone PF00125.19 EPX72488.1 - 0.0018 18.3 0.1 0.021 14.9 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPX72488.1 - 0.0056 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Myosin_head PF00063.16 EPX72489.1 - 1.1e-232 773.9 10.5 1.5e-232 773.5 7.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EPX72489.1 - 8.1e-21 73.8 0.1 3.5e-20 71.8 0.1 2.2 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EPX72489.1 - 1.8e-12 45.7 14.9 0.011 15.2 0.4 6.6 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 EPX72489.1 - 0.0018 18.4 0.0 0.0076 16.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EPX72489.1 - 0.0037 16.2 0.1 0.015 14.2 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EPX72489.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EPX72489.1 - 0.05 13.5 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain EST1_DNA_bind PF10373.4 EPX72490.1 - 2e-14 53.4 5.3 2e-14 53.4 3.7 2.6 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EPX72490.1 - 7.9e-14 51.7 4.7 2.3e-13 50.2 3.3 1.8 1 0 0 1 1 1 1 Telomerase activating protein Est1 XPC-binding PF09280.6 EPX72491.1 - 1.3e-25 88.6 8.7 2.9e-25 87.5 6.0 1.6 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 EPX72491.1 - 2.6e-21 74.7 4.1 6.4e-11 41.7 0.3 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 EPX72491.1 - 8.6e-21 73.1 1.2 1.4e-20 72.4 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPX72491.1 - 8.1e-09 35.0 1.6 1.4e-08 34.2 1.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPX72491.1 - 3.9e-05 23.7 0.7 6.4e-05 23.0 0.0 1.7 2 0 0 2 2 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EPX72491.1 - 8.3e-05 22.4 0.1 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SOG2 PF10428.4 EPX72491.1 - 0.00034 19.4 10.3 0.00047 18.9 7.1 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Rap1_C PF11626.3 EPX72491.1 - 0.0014 18.4 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain MCM_N PF14551.1 EPX72491.1 - 0.0062 17.0 0.0 0.02 15.3 0.0 1.8 2 0 0 2 2 1 1 MCM N-terminal domain UBA_3 PF09288.5 EPX72491.1 - 0.014 14.9 0.0 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain CUE PF02845.11 EPX72491.1 - 0.063 12.7 0.0 8.6 5.9 0.0 3.1 3 0 0 3 3 3 0 CUE domain DUF3135 PF11333.3 EPX72491.1 - 0.66 10.1 3.9 0.37 10.9 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3135) TFIIA PF03153.8 EPX72491.1 - 1 9.1 19.0 1.3 8.8 13.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3123 PF11321.3 EPX72491.1 - 5.9 7.2 12.4 14 6.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) NAP PF00956.13 EPX72492.1 - 6.7e-78 261.1 2.9 1e-77 260.5 2.0 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) GreA_GreB PF01272.14 EPX72492.1 - 0.043 13.5 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term Fibrillarin PF01269.12 EPX72493.1 - 1.6e-107 357.6 0.0 2e-107 357.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EPX72493.1 - 1.9e-07 30.8 0.0 2.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EPX72493.1 - 0.059 12.8 0.1 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EPX72493.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EPX72493.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Secretin_N PF03958.12 EPX72493.1 - 0.38 10.9 2.5 6 7.1 0.0 2.6 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain ECH PF00378.15 EPX72494.1 - 5.1e-35 120.7 0.0 1.3e-33 116.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EPX72494.1 - 2e-26 92.4 0.1 1.6e-25 89.5 0.0 2.1 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Ribosomal_L4 PF00573.17 EPX72495.1 - 1.1e-48 165.1 0.0 1.3e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family SLAP PF03217.9 EPX72495.1 - 0.033 14.3 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial surface layer protein Peptidase_S24 PF00717.18 EPX72496.1 - 3.8e-10 39.2 0.0 8.5e-10 38.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 EPX72496.1 - 2.8e-06 26.9 0.0 5.7e-05 22.6 0.0 2.3 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Cellulase PF00150.13 EPX72498.1 - 9.5e-11 41.4 3.6 4.3e-10 39.2 2.5 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Arrestin_C PF02752.17 EPX72499.1 - 4.5e-19 68.9 0.0 3.7e-17 62.7 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EPX72499.1 - 4.2e-11 42.8 0.0 1.7e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF866 PF05907.8 EPX72500.1 - 4.9e-50 169.1 0.6 5.4e-50 169.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.1 EPX72500.1 - 0.021 14.4 1.3 0.067 12.8 1.0 1.8 1 1 0 1 1 1 0 Cytochrome c7 Basic PF01586.11 EPX72500.1 - 0.064 13.9 1.0 0.064 13.9 0.7 1.8 2 1 0 2 2 2 0 Myogenic Basic domain zf-3CxxC PF13695.1 EPX72500.1 - 0.087 13.0 0.4 0.32 11.2 0.1 1.9 2 0 0 2 2 2 0 Zinc-binding domain zf-C4pol PF14260.1 EPX72500.1 - 0.089 12.8 4.1 0.14 12.1 1.3 2.0 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta ORC6 PF05460.8 EPX72501.1 - 2.7e-25 89.2 3.2 2.9e-21 75.9 0.1 2.1 1 1 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) SAC3_GANP PF03399.11 EPX72502.1 - 4.5e-66 222.3 1.4 5.9e-66 221.9 0.9 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPX72502.1 - 6.6e-08 32.4 1.9 1.9e-07 30.9 0.1 2.5 3 0 0 3 3 3 1 COP9 signalosome, subunit CSN8 Bin3 PF06859.7 EPX72503.1 - 8.6e-31 106.1 0.1 1.4e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.1 EPX72503.1 - 1.5e-11 44.2 0.0 2.1e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX72503.1 - 5.8e-10 38.9 0.2 3.1e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EPX72503.1 - 2.9e-08 34.2 0.0 5.8e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX72503.1 - 3.7e-05 24.1 0.0 0.033 14.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EPX72503.1 - 3.8e-05 24.0 0.0 0.011 16.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPX72503.1 - 0.00066 18.7 0.0 0.0013 17.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EPX72503.1 - 0.0019 17.6 0.0 0.02 14.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EPX72503.1 - 0.0021 18.0 0.0 0.0031 17.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EPX72503.1 - 0.0027 17.0 0.1 0.0068 15.7 0.0 1.6 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.8 EPX72503.1 - 0.0028 16.8 0.0 0.0058 15.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EPX72503.1 - 0.0081 15.2 0.0 2.9 6.9 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EPX72503.1 - 0.015 15.6 0.0 0.037 14.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 EPX72503.1 - 0.046 13.1 0.0 2.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) RrnaAD PF00398.15 EPX72503.1 - 0.048 12.6 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 EPX72503.1 - 0.063 12.4 0.0 7.2 5.7 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase PCMT PF01135.14 EPX72503.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Phosducin PF02114.11 EPX72504.1 - 2.8e-23 81.9 0.1 5.9e-23 80.9 0.1 1.4 1 1 1 2 2 2 1 Phosducin Thioredoxin PF00085.15 EPX72504.1 - 0.00057 19.5 0.0 0.00097 18.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Longin PF13774.1 EPX72505.1 - 5.4e-26 89.9 0.0 8.3e-26 89.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EPX72505.1 - 3.3e-17 61.8 0.0 4.6e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin zf-PARP PF00645.13 EPX72507.1 - 4e-21 75.0 0.1 1e-20 73.7 0.1 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Prenyltransf PF01255.14 EPX72508.1 - 1.1e-09 37.7 1.5 1.3e-09 37.5 0.0 1.8 3 0 0 3 3 3 1 Putative undecaprenyl diphosphate synthase PolyA_pol PF01743.15 EPX72508.1 - 0.021 15.0 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Poly A polymerase head domain DUF846 PF05832.7 EPX72509.1 - 9.5e-50 168.0 9.4 1.3e-49 167.5 6.5 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.1 EPX72509.1 - 0.27 10.3 1.7 1.7 7.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) zf-RING_2 PF13639.1 EPX72510.1 - 4.7e-14 51.9 21.3 7.7e-12 44.8 5.6 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 EPX72510.1 - 1.1e-09 38.1 17.8 1.6e-07 31.2 5.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX72510.1 - 6.6e-09 35.3 18.1 1.6e-06 27.7 4.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX72510.1 - 5.9e-08 32.3 19.1 9.8e-05 22.0 4.6 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-rbx1 PF12678.2 EPX72510.1 - 7.4e-06 25.9 14.2 7.7e-06 25.9 2.9 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EPX72510.1 - 7.4e-06 25.5 3.6 7.4e-06 25.5 2.5 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EPX72510.1 - 3e-05 23.5 20.5 0.00071 19.1 5.5 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EPX72510.1 - 0.014 14.9 21.8 0.16 11.6 5.5 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EPX72510.1 - 0.32 10.8 13.7 0.7 9.7 3.6 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger SRP-alpha_N PF04086.8 EPX72510.1 - 1.9 7.7 10.0 0.037 13.3 1.1 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal zf-C3HC4_4 PF15227.1 EPX72510.1 - 2 8.3 14.8 1.2 9.0 5.0 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EPX72510.1 - 5.8 6.5 14.9 0.27 10.7 3.9 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 WD40 PF00400.27 EPX72511.1 - 2.9e-08 33.2 9.1 1.6e-06 27.7 0.0 5.1 7 0 0 7 7 7 3 WD domain, G-beta repeat Sec1 PF00995.18 EPX72512.1 - 3.2e-88 296.8 0.1 3.6e-88 296.6 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Topoisom_I_N PF02919.10 EPX72513.1 - 5.4e-102 339.6 3.7 5.4e-102 339.6 2.6 2.5 2 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EPX72513.1 - 2.4e-86 288.6 2.0 6.1e-86 287.3 1.4 1.7 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EPX72513.1 - 3.1e-29 100.4 2.0 1.1e-28 98.6 1.4 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain Mito_carr PF00153.22 EPX72514.1 - 1.3e-46 156.2 6.0 5.2e-17 61.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EPX72516.1 - 1.6e-61 203.8 0.1 1.8e-20 72.3 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX72516.1 - 6.3e-43 144.6 0.1 6e-15 54.9 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX72516.1 - 1.6e-28 98.3 0.0 5.2e-12 45.4 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPX72516.1 - 0.00032 20.4 0.0 0.73 9.6 0.0 3.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF3343 PF11823.3 EPX72516.1 - 0.031 13.5 0.0 3.7 6.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3343) Rad10 PF03834.9 EPX72517.1 - 2e-29 101.0 0.1 3.4e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH PF00633.18 EPX72517.1 - 4.1e-07 29.3 0.1 1.3e-05 24.5 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EPX72517.1 - 7.5e-06 26.0 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EPX72517.1 - 0.081 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HRDC PF00570.18 EPX72517.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 HRDC domain ERO1 PF04137.10 EPX72518.1 - 6.9e-108 360.8 8.2 8.6e-108 360.5 5.7 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Fer4_18 PF13746.1 EPX72518.1 - 0.0057 17.0 0.1 0.021 15.2 0.1 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Gemini_AL3 PF01407.12 EPX72518.1 - 0.04 13.3 0.2 0.085 12.3 0.1 1.5 1 0 0 1 1 1 0 Geminivirus AL3 protein AAA_2 PF07724.9 EPX72519.1 - 3.9e-51 173.3 0.9 3.1e-48 163.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EPX72519.1 - 5.2e-25 87.1 0.2 2.1e-24 85.2 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EPX72519.1 - 4.1e-19 69.0 0.1 7.4e-09 35.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPX72519.1 - 6.6e-16 58.8 5.8 6.1e-06 26.3 0.0 4.6 3 3 1 4 4 4 3 AAA ATPase domain AAA_5 PF07728.9 EPX72519.1 - 5.9e-14 51.9 0.1 7e-10 38.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPX72519.1 - 2.8e-09 37.1 3.8 0.00027 21.0 0.0 4.4 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EPX72519.1 - 5e-08 32.5 0.1 2.2e-06 27.2 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EPX72519.1 - 1.2e-07 31.3 0.1 0.031 13.7 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.1 EPX72519.1 - 7.6e-07 29.9 2.5 0.044 14.5 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EPX72519.1 - 1.3e-06 28.3 0.0 0.091 12.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EPX72519.1 - 2e-06 27.6 8.5 0.0066 16.1 0.1 4.6 3 2 0 3 3 3 2 Archaeal ATPase NACHT PF05729.7 EPX72519.1 - 2.8e-06 27.0 0.1 0.031 13.9 0.0 3.1 3 0 0 3 3 2 2 NACHT domain Mg_chelatase PF01078.16 EPX72519.1 - 1.5e-05 24.2 0.8 0.6 9.2 0.0 3.7 3 1 1 4 4 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EPX72519.1 - 4.5e-05 23.4 0.7 2 8.3 0.0 4.1 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 EPX72519.1 - 5.1e-05 23.3 0.0 1.1 9.4 0.0 3.5 3 0 0 3 3 3 2 RNA helicase ResIII PF04851.10 EPX72519.1 - 0.00022 21.0 2.7 0.041 13.7 0.0 3.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit MobB PF03205.9 EPX72519.1 - 0.00023 20.8 0.0 0.54 9.9 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EPX72519.1 - 0.00035 20.0 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EPX72519.1 - 0.00042 20.6 5.1 0.35 11.1 0.0 3.8 4 1 0 4 4 3 2 AAA domain DUF258 PF03193.11 EPX72519.1 - 0.00043 19.4 0.0 1.1 8.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DNA_pol3_delta2 PF13177.1 EPX72519.1 - 0.0007 19.2 0.0 0.0071 16.0 0.0 2.5 3 0 0 3 3 2 1 DNA polymerase III, delta subunit AAA_25 PF13481.1 EPX72519.1 - 0.00074 18.9 0.1 0.89 8.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPX72519.1 - 0.0009 19.5 3.0 0.22 11.8 0.0 3.5 3 2 0 3 3 3 1 ABC transporter MMR_HSR1 PF01926.18 EPX72519.1 - 0.0019 18.1 0.0 3.1 7.7 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase RuvB_N PF05496.7 EPX72519.1 - 0.0036 16.3 1.3 0.39 9.7 0.0 3.3 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 EPX72519.1 - 0.0042 16.0 0.3 0.03 13.2 0.0 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.4 EPX72519.1 - 0.0052 15.4 0.1 1.1 7.7 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain HAUS2 PF15003.1 EPX72519.1 - 0.007 15.4 1.9 0.013 14.6 1.3 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 SRP54 PF00448.17 EPX72519.1 - 0.0079 15.6 0.1 2 7.8 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_21 PF13304.1 EPX72519.1 - 0.0079 16.1 0.3 2.7 7.8 0.0 3.6 3 2 1 5 5 3 1 AAA domain AAA_19 PF13245.1 EPX72519.1 - 0.0089 15.7 0.0 4.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain ATP_bind_1 PF03029.12 EPX72519.1 - 0.01 15.4 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 EPX72519.1 - 0.012 16.0 0.3 2.5 8.6 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein AAA_30 PF13604.1 EPX72519.1 - 0.018 14.6 0.0 1.6 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EPX72519.1 - 0.026 14.1 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EPX72519.1 - 0.031 14.1 2.2 6.7 6.5 0.0 3.8 3 2 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EPX72519.1 - 0.032 13.6 5.5 0.25 10.7 0.0 3.8 3 2 0 4 4 4 0 AAA-like domain DUF87 PF01935.12 EPX72519.1 - 0.052 13.3 7.1 3.3 7.4 0.0 3.6 4 0 0 4 4 3 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 EPX72519.1 - 0.088 12.2 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EPX72519.1 - 4.9 7.4 22.5 0.96 9.7 0.0 3.9 2 2 0 2 2 1 0 AAA domain IncA PF04156.9 EPX72519.1 - 5.1 6.6 12.7 13 5.3 8.8 1.7 1 0 0 1 1 1 0 IncA protein Arf PF00025.16 EPX72520.1 - 4.6e-80 266.9 0.1 5.2e-80 266.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPX72520.1 - 5e-14 51.9 0.0 6.2e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EPX72520.1 - 7.4e-13 48.1 0.0 8e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EPX72520.1 - 3.8e-12 45.6 1.0 9.5e-09 34.4 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EPX72520.1 - 2e-11 43.4 0.0 2.4e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EPX72520.1 - 3e-09 37.4 0.0 4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPX72520.1 - 4.9e-06 26.4 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EPX72520.1 - 0.0063 15.6 0.1 0.01 14.8 0.0 1.4 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EPX72520.1 - 0.014 14.8 0.1 0.096 12.1 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EPX72520.1 - 0.089 12.6 0.1 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Peptidase_M24 PF00557.19 EPX72521.1 - 4.2e-45 153.8 0.0 6e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EPX72521.1 - 1.2e-06 29.0 0.0 1.9e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Lung_7-TM_R PF06814.8 EPX72522.1 - 1.6e-48 165.1 19.5 1.6e-48 165.1 13.5 1.4 2 0 0 2 2 2 1 Lung seven transmembrane receptor ELMO_CED12 PF04727.8 EPX72522.1 - 0.082 12.4 0.3 0.24 10.9 0.2 1.5 1 1 0 1 1 1 0 ELMO/CED-12 family Tmemb_14 PF03647.8 EPX72522.1 - 0.35 11.2 6.7 0.38 11.1 0.1 3.0 2 1 0 2 2 2 0 Transmembrane proteins 14C UvrD-helicase PF00580.16 EPX72523.1 - 9.6e-14 51.3 2.3 5.8e-09 35.6 1.6 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EPX72523.1 - 1.2e-11 44.7 0.0 2.7e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EPX72523.1 - 2.4e-08 33.8 0.1 0.033 13.7 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EPX72523.1 - 1.9e-07 31.1 0.0 4.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 EPX72523.1 - 0.00018 21.1 0.0 0.0089 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPX72523.1 - 0.00028 20.5 0.0 0.00092 18.9 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 EPX72523.1 - 0.022 13.9 0.0 1 8.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein RrnaAD PF00398.15 EPX72524.1 - 4.1e-60 203.0 0.0 4.8e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EPX72524.1 - 3.1e-11 43.3 0.0 4.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX72524.1 - 1e-06 29.2 0.0 2.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX72524.1 - 2.2e-06 27.3 0.0 4.3e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX72524.1 - 2.4e-05 24.7 0.0 5.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPX72524.1 - 3.2e-05 23.5 0.0 4.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EPX72524.1 - 4.9e-05 22.7 0.0 8.1e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EPX72524.1 - 0.00028 20.6 0.0 0.0006 19.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EPX72524.1 - 0.00042 19.9 0.0 0.0007 19.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.15 EPX72524.1 - 0.00047 19.3 0.0 0.00076 18.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EPX72524.1 - 0.0028 18.1 0.0 0.0064 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EPX72524.1 - 0.0045 15.9 0.0 0.008 15.0 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase PRMT5 PF05185.11 EPX72524.1 - 0.0065 15.4 0.0 0.0093 14.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_2 PF00891.13 EPX72524.1 - 0.02 14.0 0.1 0.059 12.5 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase Ubie_methyltran PF01209.13 EPX72524.1 - 0.05 12.6 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EPX72524.1 - 0.051 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EPX72524.1 - 0.052 13.9 0.0 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 EPX72524.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 EPX72524.1 - 0.081 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EPX72524.1 - 0.085 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 EPX72524.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RasGEF PF00617.14 EPX72525.1 - 5.8e-51 172.8 0.4 1.1e-50 171.9 0.3 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EPX72525.1 - 1.2e-18 67.1 0.7 1.2e-18 67.1 0.5 2.7 2 0 0 2 2 2 1 RasGEF N-terminal motif DNA_pol_B PF00136.16 EPX72526.1 - 3.1e-147 491.1 0.1 4.5e-147 490.5 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EPX72526.1 - 2.9e-92 308.9 0.2 4.6e-92 308.3 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EPX72526.1 - 4.9e-25 87.3 5.9 1.2e-24 86.0 4.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EPX72526.1 - 0.0029 17.4 0.0 0.013 15.3 0.0 2.1 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 EPX72526.1 - 0.0055 15.4 0.9 0.0055 15.4 0.6 1.9 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral C1_1 PF00130.17 EPX72526.1 - 5.9 6.7 7.4 9.3 6.0 0.5 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNase_H PF00075.19 EPX72527.1 - 2.1e-29 102.4 0.6 2.6e-29 102.2 0.0 1.4 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.11 EPX72527.1 - 1.1e-16 60.5 1.2 2.5e-16 59.3 0.8 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF3303 PF11746.3 EPX72527.1 - 0.021 15.2 0.0 0.061 13.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3303) Ras PF00071.17 EPX72528.1 - 1.9e-65 219.1 0.7 2.4e-65 218.8 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX72528.1 - 3.4e-22 79.1 0.0 5.4e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX72528.1 - 1.2e-17 63.7 0.2 1.5e-17 63.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPX72528.1 - 1.4e-06 27.6 0.1 2.2e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPX72528.1 - 2.3e-06 27.1 0.1 4.8e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EPX72528.1 - 2.2e-05 23.7 0.1 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPX72528.1 - 6.7e-05 22.8 0.1 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EPX72528.1 - 0.00065 19.9 0.1 0.097 12.8 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPX72528.1 - 0.00092 19.3 0.0 0.0019 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPX72528.1 - 0.0023 17.9 0.1 0.073 13.0 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.13 EPX72528.1 - 0.015 14.6 0.1 0.13 11.4 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 EPX72528.1 - 0.018 14.2 0.0 0.052 12.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EPX72528.1 - 0.023 14.4 0.1 0.093 12.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 EPX72528.1 - 0.025 13.2 1.2 2.5 6.7 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.1 EPX72528.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EPX72528.1 - 0.042 14.1 0.1 0.11 12.7 0.1 1.8 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 EPX72528.1 - 0.05 12.6 0.0 0.2 10.6 0.0 1.8 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 EPX72528.1 - 0.053 13.0 0.1 1.2 8.6 0.0 2.3 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EPX72528.1 - 0.069 13.0 0.1 0.27 11.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain OPA3 PF07047.7 EPX72529.1 - 4.4e-34 117.1 0.9 4.4e-34 117.1 0.6 1.9 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) DUF572 PF04502.8 EPX72529.1 - 0.028 13.6 9.6 0.039 13.1 6.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Totivirus_coat PF05518.6 EPX72529.1 - 0.032 12.0 0.0 0.042 11.6 0.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein Striatin PF08232.7 EPX72529.1 - 0.045 14.0 7.3 0.077 13.3 5.1 1.3 1 0 0 1 1 1 0 Striatin family PEHE PF15275.1 EPX72529.1 - 0.058 13.8 4.3 0.11 12.9 3.0 1.4 1 0 0 1 1 1 0 PEHE domain DUF4612 PF15389.1 EPX72529.1 - 0.065 13.8 9.1 0.12 12.9 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) HLH PF00010.21 EPX72529.1 - 0.068 12.8 0.8 0.14 11.8 0.6 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Fmp27_WPPW PF10359.4 EPX72529.1 - 0.23 9.8 8.6 0.3 9.4 6.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Topoisom_I_N PF02919.10 EPX72529.1 - 0.71 9.1 5.5 0.49 9.6 2.4 1.6 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF2215 PF10225.4 EPX72529.1 - 0.91 8.9 3.1 0.95 8.8 1.3 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Peptidase_S49_N PF08496.5 EPX72529.1 - 7.5 6.3 9.2 15 5.3 0.2 2.4 2 1 1 3 3 3 0 Peptidase family S49 N-terminal UCH PF00443.24 EPX72530.1 - 5.4e-65 219.1 2.9 5.4e-65 219.1 2.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPX72530.1 - 1.4e-30 106.7 7.0 5.3e-29 101.5 1.4 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DDE_1 PF03184.14 EPX72531.1 - 2.1e-54 183.9 0.1 3.6e-54 183.1 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4544 PF15077.1 EPX72531.1 - 0.012 15.1 0.2 0.031 13.7 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4544) tRNA-synt_2b PF00587.20 EPX72533.1 - 4.4e-38 130.5 0.0 6.2e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPX72533.1 - 9.3e-10 38.3 0.0 2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EPX72533.1 - 0.11 11.2 0.0 0.39 9.4 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) zf-TFIIB PF13453.1 EPX72533.1 - 0.11 11.6 1.2 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger Aldedh PF00171.17 EPX72534.1 - 1.6e-104 349.8 0.0 2e-104 349.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Coatomer_E PF04733.9 EPX72535.1 - 3.9e-69 233.0 4.2 4.6e-69 232.8 2.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_12 PF13424.1 EPX72535.1 - 0.00091 19.1 6.7 0.12 12.3 1.9 3.7 2 1 1 4 4 4 2 Tetratricopeptide repeat CReP_N PF10472.4 EPX72535.1 - 0.0041 15.8 0.3 0.0056 15.4 0.2 1.1 1 0 0 1 1 1 1 eIF2-alpha phosphatase phosphorylation constitutive repressor Apc3 PF12895.2 EPX72535.1 - 0.33 11.1 5.3 8 6.6 0.2 3.4 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4398 PF14346.1 EPX72535.1 - 2.3 8.3 6.3 5.3 7.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) G-alpha PF00503.15 EPX72536.1 - 4.3e-107 358.1 0.2 5e-107 357.9 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EPX72536.1 - 1e-13 50.8 0.1 8.5e-09 34.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EPX72536.1 - 0.0032 17.9 0.0 4.4 7.8 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EPX72536.1 - 0.0041 16.6 0.1 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EPX72536.1 - 0.018 14.1 2.2 2.8 7.0 0.1 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPX72536.1 - 0.12 11.8 0.0 6.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Folliculin PF11704.3 EPX72537.1 - 2.1e-52 177.0 0.0 3.6e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport CDC14 PF08045.6 EPX72538.1 - 6.9e-59 199.0 3.0 3.4e-58 196.7 2.1 1.8 1 1 0 1 1 1 1 Cell division control protein 14, SIN component Cnd1 PF12717.2 EPX72538.1 - 0.078 12.8 1.0 1.6 8.5 0.7 2.1 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 XFP_N PF09364.5 EPX72539.1 - 5.2e-168 558.4 0.0 6.8e-168 558.0 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EPX72539.1 - 2.6e-74 248.6 0.0 4.2e-74 248.0 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EPX72539.1 - 1.7e-64 216.9 0.1 3.2e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain Transketolase_C PF02780.15 EPX72539.1 - 0.053 13.4 0.1 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 EPX72539.1 - 0.054 13.0 0.1 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain COX6B PF02297.12 EPX72540.1 - 3e-19 68.7 10.0 3.5e-19 68.5 6.9 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EPX72540.1 - 0.044 13.8 2.6 0.084 12.9 1.8 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF2013 PF09431.5 EPX72541.1 - 1.9e-43 147.6 4.8 1.9e-43 147.6 3.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) G10 PF01125.12 EPX72542.1 - 2.3e-63 212.1 2.6 2.5e-63 211.9 1.8 1.0 1 0 0 1 1 1 1 G10 protein MutS_V PF00488.16 EPX72543.1 - 3.1e-96 321.3 0.5 3.1e-96 321.3 0.4 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EPX72543.1 - 1.6e-33 116.2 1.5 1.6e-33 116.2 1.0 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EPX72543.1 - 6.5e-20 71.1 1.8 1.5e-19 69.9 1.2 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EPX72543.1 - 8.8e-20 71.1 1.3 3.5e-19 69.2 0.0 2.5 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.15 EPX72543.1 - 8.8e-13 48.2 0.0 1.8e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain I Aminotran_4 PF01063.14 EPX72544.1 - 1.2e-26 93.6 0.1 1.6e-26 93.2 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Ribosomal_S30 PF04758.9 EPX72545.1 - 7.5e-30 102.4 5.0 8.1e-30 102.3 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 SprT-like PF10263.4 EPX72546.1 - 3.4e-37 127.5 5.1 6e-37 126.7 3.6 1.4 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.14 EPX72546.1 - 0.0033 17.6 0.1 0.0082 16.3 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box MT-A70 PF05063.9 EPX72546.1 - 0.072 12.6 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 MT-A70 Glucan_synthase PF02364.10 EPX72547.1 - 0 1304.3 0.0 0 1303.6 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EPX72547.1 - 1.4e-37 128.2 1.3 2.9e-37 127.1 0.9 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SRF-TF PF00319.13 EPX72548.1 - 4.2e-16 57.9 0.2 8.1e-16 56.9 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PPR_2 PF13041.1 EPX72549.1 - 5.5e-13 48.6 0.2 2.4e-07 30.6 0.0 3.5 2 1 1 3 3 3 2 PPR repeat family PPR PF01535.15 EPX72549.1 - 2.3e-12 46.0 0.2 5.4e-05 22.8 0.0 4.0 3 0 0 3 3 3 3 PPR repeat PPR_3 PF13812.1 EPX72549.1 - 1.3e-05 25.0 0.2 0.18 12.1 0.0 4.6 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 EPX72549.1 - 0.00038 19.8 0.1 0.66 9.5 0.0 3.1 3 0 0 3 3 3 2 PPR repeat Snapin_Pallidin PF14712.1 EPX72549.1 - 0.0027 17.9 0.3 0.015 15.6 0.2 2.2 1 0 0 1 1 1 1 Snapin/Pallidin Fumble PF03630.9 EPX72549.1 - 0.019 13.8 0.1 0.033 13.0 0.1 1.3 1 0 0 1 1 1 0 Fumble Vac_Fusion PF02346.11 EPX72549.1 - 0.032 13.6 0.1 0.14 11.5 0.1 2.2 1 0 0 1 1 1 0 Chordopoxvirus fusion protein Med4 PF10018.4 EPX72549.1 - 0.096 12.0 1.9 0.22 10.9 1.3 1.6 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Arrestin_C PF02752.17 EPX72550.1 - 5.6e-10 39.4 1.2 2.9e-09 37.1 0.1 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Peptidase_C48 PF02902.14 EPX72551.1 - 3.9e-48 163.9 0.1 6.5e-48 163.2 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PAT1 PF09770.4 EPX72552.1 - 2e-198 661.4 12.8 1.3e-197 658.7 8.9 1.8 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Baculo_gp41 PF04700.7 EPX72552.1 - 0.094 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region DUF4257 PF14074.1 EPX72553.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) TRF PF08558.5 EPX72554.1 - 2.1e-67 226.9 0.1 2.9e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EPX72554.1 - 2.7e-06 27.3 0.4 4.8e-06 26.5 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPX72554.1 - 0.0069 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain COG5 PF10392.4 EPX72555.1 - 1.3e-28 99.6 1.1 3.4e-28 98.2 0.7 1.8 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.9 EPX72555.1 - 0.0014 18.2 0.9 0.0039 16.8 0.6 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain MutS_III PF05192.13 EPX72555.1 - 0.028 14.2 1.3 0.047 13.4 0.9 1.4 1 0 0 1 1 1 0 MutS domain III MCM_N PF14551.1 EPX72555.1 - 0.1 13.0 1.0 17 5.9 0.2 2.5 2 0 0 2 2 2 0 MCM N-terminal domain IncA PF04156.9 EPX72555.1 - 0.16 11.5 3.6 0.073 12.6 0.3 1.9 1 1 1 2 2 2 0 IncA protein ING PF12998.2 EPX72555.1 - 0.37 11.1 6.1 2.1 8.6 0.2 3.4 3 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DNA_primase_lrg PF04104.9 EPX72555.1 - 0.37 10.0 2.7 0.56 9.4 0.3 2.3 2 1 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit Nup54 PF13874.1 EPX72556.1 - 6.1e-39 132.9 2.3 6.1e-39 132.9 1.6 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Atg14 PF10186.4 EPX72556.1 - 3.4 6.5 8.6 3.2 6.6 3.2 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tom5 PF10642.4 EPX72557.1 - 1.1e-06 28.1 0.0 1.3e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Med26 PF08711.6 EPX72558.1 - 3e-15 55.4 2.3 5.2e-15 54.6 0.1 2.6 3 0 0 3 3 3 1 TFIIS helical bundle-like domain SecY PF00344.15 EPX72559.1 - 2e-47 161.7 24.4 2.7e-47 161.3 16.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EPX72559.1 - 2.1e-05 23.9 0.4 0.00099 18.5 0.0 3.5 3 1 0 3 3 3 1 Plug domain of Sec61p Svf1 PF08622.5 EPX72560.1 - 2.4e-52 177.9 0.1 2.8e-52 177.7 0.1 1.0 1 0 0 1 1 1 1 Svf1-like Sec63 PF02889.11 EPX72561.1 - 2.1e-27 96.2 0.1 1.5e-22 80.2 0.0 2.3 1 1 1 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 EPX72561.1 - 3e-16 58.9 0.2 5.2e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4511 PF14974.1 EPX72561.1 - 0.063 13.0 0.0 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4511) Dus PF01207.12 EPX72562.1 - 1.5e-67 227.6 0.0 1.8e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) FYVE PF01363.16 EPX72563.1 - 5e-19 67.9 12.0 5e-19 67.9 8.3 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EPX72563.1 - 1.6e-08 34.1 24.9 1.8e-08 34.0 1.9 4.4 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.1 EPX72563.1 - 8.7 6.4 30.0 0.082 12.9 2.2 5.1 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Nsp1_C PF05064.8 EPX72564.1 - 0.019 14.6 7.7 0.33 10.6 2.1 3.0 1 1 1 2 2 2 0 Nsp1-like C-terminal region MSV199 PF10553.4 EPX72564.1 - 0.092 12.6 6.9 0.28 11.0 4.8 1.8 1 1 0 1 1 1 0 MSV199 domain G-gamma PF00631.17 EPX72564.1 - 0.36 10.5 2.8 0.64 9.7 0.0 2.5 2 1 1 3 3 3 0 GGL domain FlaC_arch PF05377.6 EPX72564.1 - 1.3 8.9 7.1 1.2 9.1 0.5 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) WXG100 PF06013.7 EPX72564.1 - 2.1 8.4 6.9 19 5.3 1.8 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.6 EPX72565.1 - 1.3e-20 73.5 0.5 1.9e-19 69.8 0.1 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EPX72565.1 - 1e-14 53.9 1.2 1e-14 53.9 0.8 2.4 3 0 0 3 3 3 1 SNARE domain Protoglobin PF11563.3 EPX72565.1 - 0.022 14.4 0.1 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Protoglobin DUF745 PF05335.8 EPX72565.1 - 0.11 11.9 0.9 0.26 10.7 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) NAP PF00956.13 EPX72566.1 - 3.8e-31 108.0 11.3 3.8e-31 108.0 7.9 1.9 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) Pkinase PF00069.20 EPX72567.1 - 4.4e-76 255.4 2.2 4.4e-42 144.0 0.0 4.0 4 0 0 4 4 4 3 Protein kinase domain HGTP_anticodon2 PF12745.2 EPX72567.1 - 1.2e-58 198.4 11.0 1.2e-58 198.4 7.6 2.6 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 EPX72567.1 - 9.1e-48 162.5 0.1 2.3e-23 82.6 0.0 4.4 4 0 0 4 4 4 3 Protein tyrosine kinase RWD PF05773.17 EPX72567.1 - 4.9e-19 68.3 0.4 2.1e-18 66.2 0.0 2.4 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.1 EPX72567.1 - 4.4e-11 42.3 0.2 1.3e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 EPX72567.1 - 9e-07 28.1 0.0 0.0032 16.4 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EPX72567.1 - 6.3e-05 22.1 1.2 0.13 11.3 0.0 3.0 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX72567.1 - 0.00074 19.3 0.2 0.031 14.0 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family PLDc_2 PF13091.1 EPX72568.1 - 1.1e-12 47.8 0.0 5.7e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EPX72568.1 - 0.0036 17.0 3.4 0.23 11.3 0.0 3.5 3 0 0 3 3 3 1 Phospholipase D Active site motif Ribosomal_L35Ae PF01247.13 EPX72570.1 - 8.6e-41 137.6 0.1 9.7e-41 137.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EPX72570.1 - 0.0013 18.5 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain TAP_C PF03943.8 EPX72571.1 - 1.2e-22 79.0 0.6 2.5e-22 78.0 0.4 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EPX72571.1 - 5e-06 26.0 4.5 0.001 18.6 0.8 3.1 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPX72571.1 - 0.0095 15.6 0.6 0.03 14.0 0.1 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.1 EPX72571.1 - 0.01 15.3 0.1 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat ATP_transf PF09830.4 EPX72571.1 - 0.044 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 ATP adenylyltransferase LRR_1 PF00560.28 EPX72571.1 - 0.17 12.0 1.7 87 3.7 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EPX72571.1 - 0.53 10.7 3.8 11 6.7 0.5 3.6 3 0 0 3 3 3 0 Leucine rich repeat Rad60-SLD PF11976.3 EPX72572.1 - 2.4e-22 78.3 0.1 5.7e-17 61.1 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EPX72572.1 - 0.0012 18.1 0.1 0.0026 17.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Mto2_bdg PF12808.2 EPX72572.1 - 0.024 14.7 0.1 5.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Peptidase_M1 PF01433.15 EPX72573.1 - 4.4e-131 437.5 0.3 8.5e-131 436.6 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 EPX72573.1 - 9.6e-81 271.5 0.1 1.4e-80 270.9 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EPX72573.1 - 8.8e-18 64.5 0.1 1.5e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily HEAT_2 PF13646.1 EPX72573.1 - 0.031 14.5 0.0 0.091 13.0 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats P53_TAD PF08563.6 EPX72573.1 - 0.63 9.1 2.7 0.47 9.5 0.3 1.9 2 0 0 2 2 2 0 P53 transactivation motif Galactosyl_T PF01762.16 EPX72574.1 - 2.6e-10 40.2 0.2 0.00031 20.3 0.0 3.2 2 1 0 2 2 2 2 Galactosyltransferase Fringe PF02434.11 EPX72574.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Fringe-like DUF1325 PF07039.6 EPX72575.1 - 1.3e-30 105.6 0.0 1.8e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.1 EPX72575.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) BAR PF03114.13 EPX72576.1 - 9.7e-60 201.9 3.1 1.2e-59 201.6 2.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EPX72576.1 - 4.7e-14 51.5 0.0 8.6e-14 50.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPX72576.1 - 1.1e-12 47.3 0.1 1.8e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPX72576.1 - 9.1e-11 41.0 0.1 1.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EPX72576.1 - 0.12 11.6 7.5 0.61 9.3 5.2 1.9 1 1 0 1 1 1 0 Vps5 C terminal like Aminotran_5 PF00266.14 EPX72577.1 - 2.6e-93 312.7 0.0 3.2e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPX72577.1 - 1.4e-05 24.3 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EPX72577.1 - 0.0014 17.7 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EPX72577.1 - 0.0031 16.5 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family B12-binding PF02310.14 EPX72577.1 - 0.0048 16.7 0.0 0.45 10.3 0.0 2.4 2 0 0 2 2 2 1 B12 binding domain Bromodomain PF00439.20 EPX72578.1 - 7.7e-18 64.2 0.1 3.6e-17 62.0 0.0 2.1 3 0 0 3 3 3 1 Bromodomain Allexi_40kDa PF05549.6 EPX72578.1 - 0.0025 17.1 3.2 0.0042 16.4 2.2 1.3 1 0 0 1 1 1 1 Allexivirus 40kDa protein LemA PF04011.7 EPX72578.1 - 0.023 13.7 1.0 0.047 12.8 0.7 1.4 1 0 0 1 1 1 0 LemA family OmpH PF03938.9 EPX72578.1 - 0.028 14.3 6.7 0.029 14.2 3.8 1.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Ndc1_Nup PF09531.5 EPX72578.1 - 0.057 11.8 2.9 0.07 11.5 2.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Prp18 PF02840.10 EPX72578.1 - 0.67 9.7 2.8 7.6 6.3 0.8 2.4 2 0 0 2 2 2 0 Prp18 domain Peptidase_M3_N PF08439.5 EPX72578.1 - 2.6 8.1 5.5 1.5 8.9 0.6 2.7 3 0 0 3 3 3 0 Oligopeptidase F PCRF PF03462.13 EPX72578.1 - 3.8 7.2 6.0 2.7 7.6 0.0 2.9 2 1 0 2 2 2 0 PCRF domain zf-rbx1 PF12678.2 EPX72579.1 - 3.7e-09 36.5 3.6 1e-08 35.1 2.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPX72579.1 - 4.8e-09 35.8 8.4 1.6e-08 34.1 5.8 2.0 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EPX72579.1 - 1.7e-06 27.9 5.2 6.5e-06 26.0 3.6 2.0 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 EPX72579.1 - 5.1e-06 26.0 8.7 1.8e-05 24.2 6.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPX72579.1 - 9.6e-06 25.3 2.6 2.3e-05 24.1 1.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EPX72579.1 - 0.00093 19.1 9.2 0.00093 19.1 6.4 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX72579.1 - 0.0032 17.0 6.8 0.0088 15.6 4.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EPX72579.1 - 0.0045 16.9 7.9 0.011 15.7 5.5 1.7 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.17 EPX72579.1 - 0.41 10.4 9.1 0.13 11.9 2.4 2.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.1 EPX72579.1 - 5.1 6.7 11.7 0.34 10.5 3.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EPX72579.1 - 5.3 6.8 9.7 0.92 9.2 2.8 2.8 3 0 0 3 3 2 0 RING-type zinc-finger DUF4093 PF13331.1 EPX72580.1 - 0.012 15.7 0.5 0.76 10.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4093) Cmc1 PF08583.5 EPX72581.1 - 3.8e-14 52.1 8.3 9.4e-14 50.9 5.8 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 EPX72581.1 - 0.00032 20.0 3.1 0.00032 20.0 2.1 1.9 1 1 1 2 2 2 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cid2 PF09774.4 EPX72581.1 - 0.0074 16.4 5.6 0.0093 16.0 3.9 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Citrate_ly_lig PF08218.6 EPX72581.1 - 0.047 13.1 0.1 0.048 13.1 0.1 1.1 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain Tom37_C PF11801.3 EPX72581.1 - 0.048 13.5 4.0 0.056 13.3 2.8 1.0 1 0 0 1 1 1 0 Tom37 C-terminal domain DIPSY PF11763.3 EPX72583.1 - 2.4e-35 121.0 1.9 1.1e-34 118.8 1.3 2.3 1 0 0 1 1 1 1 Cell-wall adhesin ligand-binding C-terminal Candida_ALS PF05792.8 EPX72583.1 - 0.0056 16.7 15.4 0.0056 16.7 10.7 18.3 17 1 0 17 17 17 5 Candida agglutinin-like (ALS) ArfGap PF01412.13 EPX72584.1 - 2.4e-40 136.9 0.2 4.6e-40 136.0 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 EPX72584.1 - 8.2e-05 22.3 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF4603 PF15376.1 EPX72584.1 - 0.026 11.7 1.5 0.037 11.2 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) MFS_1 PF07690.11 EPX72585.1 - 2.3e-39 135.1 51.3 2.3e-39 135.1 35.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPX72585.1 - 1.9e-12 46.2 16.0 1.4e-11 43.2 8.4 2.5 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPX72585.1 - 9.7e-12 44.1 15.4 9.7e-12 44.1 10.7 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter Phage_holin_5 PF06946.6 EPX72585.1 - 1.3 9.2 6.3 2.6 8.2 2.0 2.7 2 0 0 2 2 2 0 Phage holin Glyoxalase PF00903.20 EPX72586.1 - 4.7e-42 142.9 0.5 1.7e-21 76.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EPX72586.1 - 8.5e-31 106.7 0.0 1.6e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EPX72586.1 - 1.2e-21 76.7 0.2 3.6e-09 36.5 0.0 3.7 2 1 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EPX72586.1 - 2.3e-07 30.8 0.0 0.0047 16.8 0.0 3.9 2 1 1 3 3 3 2 Glyoxalase-like domain CppA_N PF14506.1 EPX72586.1 - 0.028 14.0 0.0 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 CppA N-terminal CppA_C PF14507.1 EPX72586.1 - 0.062 13.4 0.3 6.2 7.0 0.1 2.5 2 0 0 2 2 2 0 CppA C-terminal SIS PF01380.17 EPX72587.1 - 1.2e-59 199.6 0.0 1.3e-33 115.3 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EPX72587.1 - 6.9e-28 97.3 0.1 4.2e-19 68.4 0.0 2.7 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EPX72587.1 - 1.6e-16 60.4 0.0 3.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EPX72587.1 - 2.2e-10 40.3 0.0 5.6e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EPX72587.1 - 4.4e-07 28.8 0.2 7.6e-07 28.0 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PAH PF02671.16 EPX72588.1 - 8.4e-41 137.3 9.1 4.7e-15 54.9 0.0 4.1 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EPX72588.1 - 3.1e-36 123.1 0.0 3.1e-36 123.1 0.0 2.8 3 0 0 3 3 3 1 Sin3 family co-repressor HlyIII PF03006.15 EPX72589.1 - 2.1e-63 213.7 25.5 2.5e-63 213.4 17.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 EPX72589.1 - 0.24 11.2 4.4 7.9 6.4 2.7 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF962) Dynamin_M PF01031.15 EPX72590.1 - 1.3e-100 336.0 0.0 2.1e-100 335.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EPX72590.1 - 3.2e-53 179.9 0.1 7.6e-53 178.7 0.1 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EPX72590.1 - 1.1e-24 86.1 5.4 1.1e-24 86.1 3.7 2.3 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EPX72590.1 - 0.004 17.1 0.1 0.019 14.9 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPX72590.1 - 0.006 17.0 0.1 0.02 15.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Ribosomal_L7Ae PF01248.21 EPX72591.1 - 1.4e-27 95.0 0.0 1.6e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.20 EPX72592.1 - 4.9e-63 212.7 0.0 8.6e-63 211.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72592.1 - 1.5e-33 115.9 0.0 3e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX72592.1 - 0.00026 20.0 0.0 0.00092 18.2 0.0 1.8 1 1 0 1 1 1 1 Kinase-like RabGAP-TBC PF00566.13 EPX72592.1 - 0.0044 16.5 3.2 0.01 15.3 0.0 2.7 3 0 0 3 3 3 1 Rab-GTPase-TBC domain APH PF01636.18 EPX72592.1 - 0.014 15.1 0.0 0.094 12.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Vac_ImportDeg PF09783.4 EPX72593.1 - 6.9e-52 175.5 2.1 7.8e-52 175.3 1.5 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Pkinase PF00069.20 EPX72594.1 - 2.4e-40 138.3 0.0 4.2e-40 137.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72594.1 - 5.7e-23 81.3 0.0 2.2e-22 79.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX72594.1 - 9.5e-07 28.0 0.0 0.0007 18.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.6 EPX72594.1 - 0.044 12.6 0.2 0.15 10.8 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.18 EPX72594.1 - 0.08 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-HC5HC2H_2 PF13832.1 EPX72595.1 - 9.7e-16 57.7 24.1 2e-15 56.7 1.3 4.6 4 0 0 4 4 4 2 PHD-zinc-finger like domain BAH PF01426.13 EPX72595.1 - 7.4e-14 51.5 0.1 1.6e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.1 EPX72595.1 - 7.4e-10 38.8 21.3 1.8e-09 37.5 0.0 4.8 5 0 0 5 5 5 2 PHD-like zinc-binding domain PHD PF00628.24 EPX72595.1 - 3.7e-08 32.9 11.3 3.7e-08 32.9 7.8 6.8 6 1 0 6 6 6 3 PHD-finger Prok-RING_1 PF14446.1 EPX72595.1 - 0.0069 16.0 23.1 0.011 15.4 0.4 4.3 4 0 0 4 4 4 2 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EPX72595.1 - 0.012 14.9 0.5 0.012 14.9 0.4 5.9 6 0 0 6 6 6 0 PHD-finger zf-C2H2_4 PF13894.1 EPX72596.1 - 5.4e-09 35.7 14.4 0.00027 21.0 4.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPX72596.1 - 9.1e-09 35.1 17.5 0.0002 21.4 4.8 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EPX72596.1 - 0.00022 21.2 8.5 0.035 14.2 2.8 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPX72596.1 - 0.0011 19.1 5.2 0.043 14.0 1.2 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EPX72596.1 - 0.03 14.6 4.0 0.03 14.6 2.8 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-UBR PF02207.15 EPX72596.1 - 0.05 13.3 2.6 0.12 12.0 1.8 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-C2H2_6 PF13912.1 EPX72596.1 - 0.058 13.3 10.3 0.061 13.2 0.3 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 EPX72596.1 - 0.18 11.6 6.5 0.11 12.3 0.9 2.6 2 0 0 2 2 2 0 BED zinc finger DUF629 PF04780.7 EPX72596.1 - 0.23 9.9 2.2 0.34 9.3 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) ORC3_N PF07034.6 EPX72597.1 - 6.6e-11 41.7 6.4 6.4e-06 25.3 0.0 3.3 3 1 1 4 4 4 2 Origin recognition complex (ORC) subunit 3 N-terminus Peptidase_M16_C PF05193.16 EPX72598.1 - 1.5e-19 70.3 0.0 2e-12 47.1 0.0 2.8 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EPX72598.1 - 2.5e-13 50.0 0.0 6.4e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) FliM PF02154.10 EPX72598.1 - 0.063 12.9 0.0 0.79 9.3 0.0 2.4 2 0 0 2 2 2 0 Flagellar motor switch protein FliM MDM31_MDM32 PF08118.6 EPX72599.1 - 8.2e-133 443.4 2.6 1.7e-132 442.4 1.8 1.3 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins LAGLIDADG_WhiA PF14527.1 EPX72599.1 - 0.072 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain HCNGP PF07818.8 EPX72600.1 - 1e-20 73.5 0.6 1e-20 73.5 0.4 1.4 2 0 0 2 2 2 1 HCNGP-like protein Transposase_21 PF02992.9 EPX72600.1 - 0.039 13.0 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Transposase family tnp2 Peptidase_M48 PF01435.13 EPX72601.1 - 5.8e-55 186.3 0.0 8.1e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF955 PF06114.8 EPX72601.1 - 0.071 12.8 0.1 1.3 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF955) SprT-like PF10263.4 EPX72601.1 - 0.23 11.1 0.7 0.62 9.7 0.5 1.5 1 1 0 1 1 1 0 SprT-like family DUF2062 PF09835.4 EPX72601.1 - 0.97 9.0 4.9 6.4 6.3 1.3 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) Arginase PF00491.16 EPX72602.1 - 1.4e-73 247.5 0.0 1.6e-73 247.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF1640 PF07798.6 EPX72603.1 - 1.6e-27 96.7 9.3 1.9e-27 96.4 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Prominin PF05478.6 EPX72603.1 - 0.00061 17.4 1.1 0.00065 17.3 0.8 1.1 1 0 0 1 1 1 1 Prominin DUF3436 PF11918.3 EPX72603.1 - 0.12 12.5 0.4 0.96 9.7 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3436) DUF883 PF05957.8 EPX72603.1 - 0.31 11.4 2.3 0.73 10.2 1.6 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) HALZ PF02183.13 EPX72603.1 - 0.69 9.6 2.8 2.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper UPF0449 PF15136.1 EPX72603.1 - 2.1 8.5 10.0 0.19 11.9 2.4 2.5 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 PTPlike_phytase PF14566.1 EPX72603.1 - 2.5 8.1 6.4 13 5.8 2.8 2.3 1 1 1 2 2 2 0 Inositol hexakisphosphate Aa_trans PF01490.13 EPX72604.1 - 8.9e-90 301.0 39.8 1.1e-89 300.8 27.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phytochelatin PF05023.9 EPX72605.1 - 5e-81 270.7 0.0 7.9e-81 270.0 0.0 1.3 1 0 0 1 1 1 1 Phytochelatin synthase YlbD_coat PF14071.1 EPX72605.1 - 0.014 15.4 0.2 0.62 10.1 0.0 2.4 2 0 0 2 2 2 0 Putative coat protein DUF1706 PF08020.6 EPX72605.1 - 0.23 10.9 1.6 0.26 10.7 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) Tmemb_14 PF03647.8 EPX72606.1 - 6.2e-21 74.6 10.0 6.9e-21 74.4 6.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Peptidase_M48 PF01435.13 EPX72607.1 - 2.8e-36 125.2 0.1 4e-36 124.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 V-SNARE_C PF12352.3 EPX72608.1 - 1.4e-16 60.3 0.6 3.2e-16 59.1 0.4 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EPX72608.1 - 4.1e-07 29.6 0.2 1.5e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Sec20 TF_AP-2 PF03299.9 EPX72608.1 - 0.013 15.1 0.1 0.051 13.1 0.0 1.8 2 0 0 2 2 2 0 Transcription factor AP-2 HTH_AraC PF00165.18 EPX72608.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF1649 PF07855.7 EPX72608.1 - 0.13 11.9 0.2 0.25 11.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1649) DUF4200 PF13863.1 EPX72608.1 - 0.13 12.1 3.1 0.35 10.8 2.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) CorA PF01544.13 EPX72608.1 - 0.17 10.8 1.3 0.35 9.8 0.9 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Tropomyosin_1 PF12718.2 EPX72608.1 - 5.4 6.8 6.5 7.9 6.3 0.3 2.9 2 1 1 3 3 3 0 Tropomyosin like FHA PF00498.21 EPX72609.1 - 1.1e-05 25.5 0.2 2.3e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 FHA domain HSP70 PF00012.15 EPX72610.1 - 1.7e-159 531.5 0.1 2.4e-159 531.0 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPX72610.1 - 8.6e-11 41.0 0.1 2.2e-10 39.6 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EPX72610.1 - 0.0079 16.0 5.3 0.63 9.8 0.3 3.9 2 2 0 2 2 2 2 Cell division protein FtsA Ras PF00071.17 EPX72611.1 - 1.9e-52 176.9 0.0 2.2e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX72611.1 - 8.8e-16 58.4 0.0 1.3e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX72611.1 - 7.1e-08 31.8 0.0 1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family HEAT_2 PF13646.1 EPX72612.1 - 3.3e-07 30.5 0.0 0.00055 20.1 0.0 4.8 5 1 0 5 5 5 1 HEAT repeats HEAT PF02985.17 EPX72612.1 - 8e-07 28.6 0.2 0.091 12.8 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EPX72612.1 - 0.00045 20.6 1.3 3.2 8.3 0.0 4.4 4 0 0 4 4 4 2 HEAT-like repeat DUF2435 PF10363.4 EPX72612.1 - 0.0084 15.9 2.1 13 5.7 0.0 4.8 3 1 1 4 4 4 2 Protein of unknown function (DUF2435) Pkinase PF00069.20 EPX72613.1 - 1.7e-60 204.3 0.0 2.9e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72613.1 - 5.5e-35 120.6 0.0 8.3e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX72613.1 - 7.2e-09 35.0 0.0 1.9e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPX72613.1 - 0.0061 16.3 0.0 0.014 15.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EPX72613.1 - 0.013 14.5 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPX72613.1 - 0.096 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF4078 PF13300.1 EPX72614.1 - 2.4e-18 66.0 5.1 2.4e-18 66.0 3.5 3.1 3 1 1 4 4 4 1 Domain of unknown function (DUF4078) Arb1 PF09692.5 EPX72615.1 - 2.4e-82 276.9 2.1 2.9e-82 276.6 1.5 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 RRM_1 PF00076.17 EPX72616.1 - 3.1e-39 132.4 0.4 4e-20 71.2 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX72616.1 - 1.6e-32 111.2 0.0 2.7e-16 59.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX72616.1 - 4.6e-15 55.2 0.0 4.3e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fer2_3 PF13085.1 EPX72617.1 - 2.6e-33 114.1 0.1 4.5e-33 113.3 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EPX72617.1 - 1.6e-10 41.1 6.8 1.6e-10 41.1 4.7 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EPX72617.1 - 4.1e-08 33.1 5.5 4.1e-08 33.1 3.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EPX72617.1 - 5.3e-05 23.5 3.1 5.3e-05 23.5 2.1 2.8 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EPX72617.1 - 0.0027 17.4 0.7 0.0027 17.4 0.5 2.4 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_10 PF13237.1 EPX72617.1 - 0.017 14.9 9.5 0.017 14.9 6.6 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 EPX72617.1 - 0.13 12.5 14.9 4.2 7.7 0.0 3.2 2 1 0 2 2 2 0 4Fe-4S dicluster domain AFT PF08731.6 EPX72617.1 - 0.14 12.4 0.0 0.78 9.9 0.0 2.1 2 0 0 2 2 2 0 Transcription factor AFT DNA_pol3_tau_4 PF12168.3 EPX72617.1 - 1.4 9.3 6.3 0.12 12.8 0.6 2.0 3 0 0 3 3 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_7 PF12838.2 EPX72617.1 - 2.5 8.5 18.6 0.1 13.0 7.2 2.7 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 EPX72617.1 - 3 8.4 8.5 1.4 9.5 0.1 2.7 3 0 0 3 3 2 0 4Fe-4S single cluster domain Arv1 PF04161.8 EPX72618.1 - 2.6e-46 158.1 7.7 2.6e-46 158.1 5.3 1.7 2 0 0 2 2 2 1 Arv1-like family F-box PF00646.28 EPX72619.1 - 0.068 12.8 0.3 0.86 9.3 0.0 2.5 2 0 0 2 2 2 0 F-box domain ALO PF04030.9 EPX72621.1 - 4.5e-73 246.0 2.3 6.1e-73 245.5 1.6 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EPX72621.1 - 6.4e-30 103.4 0.1 1.1e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NLE PF08154.7 EPX72621.1 - 0.14 12.2 0.1 18 5.4 0.0 3.1 3 0 0 3 3 3 0 NLE (NUC135) domain NAF PF03822.9 EPX72621.1 - 0.14 11.8 0.0 0.58 9.9 0.0 2.0 1 0 0 1 1 1 0 NAF domain MAP65_ASE1 PF03999.7 EPX72622.1 - 3.9e-104 349.4 23.2 3.9e-104 349.4 16.1 1.3 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) MCLC PF05934.6 EPX72622.1 - 1.9 6.6 5.8 3.6 5.7 4.0 1.4 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) tRNA-synt_1c PF00749.16 EPX72623.1 - 7.1e-88 294.2 0.0 3.3e-48 163.9 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain Ras PF00071.17 EPX72624.1 - 1.9e-53 180.1 0.1 2.3e-53 179.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX72624.1 - 5.5e-22 78.4 0.1 8.3e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX72624.1 - 2.6e-13 49.6 0.0 2.9e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPX72624.1 - 2.8e-08 33.4 0.0 5.1e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPX72624.1 - 1.7e-06 27.9 0.0 2.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EPX72624.1 - 1.8e-05 24.0 0.0 2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EPX72624.1 - 0.00026 21.1 0.0 0.0012 18.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EPX72624.1 - 0.0015 17.7 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EPX72624.1 - 0.0023 17.1 0.1 0.0049 16.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 EPX72624.1 - 0.0029 17.2 0.1 0.011 15.4 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EPX72624.1 - 0.0034 17.1 0.1 0.0086 15.7 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 EPX72624.1 - 0.0046 16.4 0.1 0.0086 15.5 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain AAA_24 PF13479.1 EPX72624.1 - 0.0079 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EPX72624.1 - 0.0081 15.2 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_16 PF13191.1 EPX72624.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EPX72624.1 - 0.016 14.9 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EPX72624.1 - 0.036 14.3 0.6 0.11 12.7 0.4 1.8 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EPX72624.1 - 0.049 13.1 0.1 0.12 11.8 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EPX72624.1 - 0.059 12.8 0.1 0.086 12.2 0.0 1.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EPX72624.1 - 0.063 13.1 0.1 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EPX72624.1 - 0.071 12.3 0.1 0.97 8.6 0.0 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B NTPase_1 PF03266.10 EPX72624.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA PF00004.24 EPX72624.1 - 0.08 13.1 0.1 0.18 12.0 0.0 1.7 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EPX72624.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 EPX72624.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.7 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Serinc PF03348.10 EPX72626.1 - 1.7e-127 425.7 29.3 2.2e-127 425.3 20.3 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Noc2 PF03715.8 EPX72627.1 - 8.7e-100 333.4 3.0 8.7e-100 333.4 2.1 1.8 2 0 0 2 2 2 1 Noc2p family TPR_11 PF13414.1 EPX72629.1 - 1.5e-26 91.8 5.1 1.6e-21 75.6 0.3 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EPX72629.1 - 6.2e-18 63.5 9.2 4.2e-06 26.1 0.0 4.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPX72629.1 - 9.2e-18 62.6 4.6 7.8e-05 22.3 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPX72629.1 - 3.2e-13 48.7 0.8 1.7e-07 30.8 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPX72629.1 - 9.7e-12 44.4 3.8 0.0012 19.2 1.0 4.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPX72629.1 - 3.6e-10 38.8 4.1 0.0035 17.0 0.1 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPX72629.1 - 8.7e-10 39.0 11.9 2.5e-05 24.8 5.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPX72629.1 - 7.1e-09 34.8 1.9 0.04 13.7 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPX72629.1 - 7.4e-09 35.8 3.2 0.00011 22.4 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPX72629.1 - 3.8e-07 29.9 5.9 9.4e-06 25.4 1.5 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPX72629.1 - 2.6e-05 23.9 0.9 0.0014 18.4 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EPX72629.1 - 7.5e-05 22.7 0.5 0.00014 21.9 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 EPX72629.1 - 0.001 19.3 1.9 0.0076 16.5 0.4 2.4 2 1 1 3 3 3 1 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.1 EPX72629.1 - 0.0039 17.4 0.6 0.012 15.8 0.4 1.8 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation NARP1 PF12569.3 EPX72629.1 - 0.014 14.1 1.0 0.14 10.8 0.2 2.1 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 EPX72629.1 - 0.029 14.7 2.3 7 7.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPX72629.1 - 0.06 13.8 6.8 20 5.9 0.3 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 EPX72629.1 - 0.079 13.0 1.4 0.76 9.9 0.0 3.1 2 1 0 3 3 2 0 Tetratricopeptide repeat MIT PF04212.13 EPX72629.1 - 1.5 8.7 9.5 0.77 9.6 0.3 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Tcf25 PF04910.9 EPX72630.1 - 5.5e-81 272.3 1.1 5.5e-81 272.3 0.7 1.7 2 0 0 2 2 2 1 Transcriptional repressor TCF25 Protocadherin PF08374.6 EPX72630.1 - 0.95 9.0 11.3 2.1 7.9 7.9 1.5 1 0 0 1 1 1 0 Protocadherin RRM_3 PF08777.6 EPX72631.1 - 6.7e-06 25.8 0.1 4.8e-05 23.1 0.1 2.4 1 1 0 1 1 1 1 RNA binding motif DUF4653 PF15546.1 EPX72631.1 - 0.0047 16.2 0.0 0.0047 16.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4653) CPSF73-100_C PF11718.3 EPX72632.1 - 9.4e-64 214.7 1.1 1.4e-63 214.1 0.7 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EPX72632.1 - 2.5e-35 121.1 0.0 2e-34 118.2 0.0 2.3 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EPX72632.1 - 4.6e-14 52.5 1.1 1.1e-13 51.3 0.7 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPX72632.1 - 7.4e-12 45.2 0.2 7.4e-12 45.2 0.2 1.9 3 0 0 3 3 3 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EPX72632.1 - 8.9e-09 35.0 0.2 3.1e-08 33.3 0.1 2.0 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EPX72632.1 - 8.1e-07 28.8 0.2 3e-06 27.0 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Mtc PF03820.12 EPX72633.1 - 4e-123 409.9 0.0 4.5e-123 409.8 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF4244 PF14029.1 EPX72633.1 - 0.14 11.2 0.5 0.33 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) DEAD PF00270.24 EPX72634.1 - 1.7e-34 118.7 0.1 2.8e-34 118.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX72634.1 - 1.2e-26 92.3 0.0 9.9e-26 89.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX72634.1 - 5.9e-07 29.4 0.2 1.6e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EPX72634.1 - 0.024 13.7 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit GlutR_dimer PF00745.15 EPX72635.1 - 0.0086 16.0 4.9 0.0086 16.0 3.4 2.3 1 1 1 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain DUF4243 PF14027.1 EPX72635.1 - 0.024 14.1 3.8 0.056 12.8 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) Cullin PF00888.17 EPX72636.1 - 4.6e-175 583.5 20.2 6.5e-175 583.0 14.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EPX72636.1 - 1.3e-26 92.1 5.5 3.5e-26 90.8 2.8 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2096 PF09869.4 EPX72636.1 - 0.15 11.9 5.3 0.25 11.2 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2096) SKN1 PF03935.10 EPX72637.1 - 1.6e-212 706.1 1.7 1.9e-212 705.9 1.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SWIRM PF04433.12 EPX72638.1 - 3.8e-31 107.0 1.0 7.4e-31 106.1 0.1 1.9 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 EPX72638.1 - 4.2e-08 33.1 0.0 9.3e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPX72638.1 - 0.0019 18.2 0.0 0.0046 17.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Zn_ribbon_2 PF12674.2 EPX72638.1 - 0.024 14.9 0.2 0.094 13.0 0.1 2.1 1 0 0 1 1 1 0 Putative zinc ribbon domain Pheromone PF08015.6 EPX72638.1 - 4.6 8.1 6.6 3.1 8.6 0.3 3.7 4 1 1 5 5 5 0 Fungal mating-type pheromone Sec62 PF03839.11 EPX72639.1 - 2e-66 223.6 1.9 2.6e-66 223.2 1.3 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 IncA PF04156.9 EPX72639.1 - 0.46 10.0 1.8 0.42 10.1 0.4 1.6 2 0 0 2 2 2 0 IncA protein FYVE PF01363.16 EPX72640.1 - 6.2e-25 86.8 25.9 5e-16 58.3 6.4 3.1 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 EPX72640.1 - 6.1e-05 22.5 0.5 0.00019 20.9 0.3 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.11 EPX72640.1 - 0.0019 18.0 6.1 0.0019 18.0 4.2 4.4 4 1 1 5 5 5 1 AN1-like Zinc finger IBR PF01485.16 EPX72640.1 - 0.0042 16.9 22.4 0.0075 16.1 0.7 4.1 3 1 0 3 3 3 2 IBR domain zf-RING_3 PF14369.1 EPX72640.1 - 0.013 15.5 6.0 0.022 14.7 0.1 3.7 4 0 0 4 4 4 0 zinc-finger Opy2 PF09463.5 EPX72640.1 - 0.015 15.3 1.0 0.015 15.3 0.7 4.4 6 0 0 6 6 6 0 Opy2 protein zf-C2H2_4 PF13894.1 EPX72640.1 - 0.32 11.4 0.0 0.32 11.4 0.0 6.0 5 1 1 6 6 6 0 C2H2-type zinc finger zinc-ribbons_6 PF07191.7 EPX72640.1 - 0.98 9.2 20.8 4.6 7.1 0.9 4.6 3 1 1 4 4 4 0 zinc-ribbons zf-C2H2 PF00096.21 EPX72640.1 - 1.9 9.0 0.0 1.9 9.0 0.0 5.8 6 1 1 7 7 7 0 Zinc finger, C2H2 type Use1 PF09753.4 EPX72641.1 - 1e-11 44.7 7.4 1.2e-11 44.5 5.1 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 COMPASS-Shg1 PF05205.7 EPX72641.1 - 0.01 16.1 3.8 0.021 15.0 2.7 1.5 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 Ribosomal_S24e PF01282.14 EPX72642.1 - 2.9e-34 116.6 0.0 4.8e-34 116.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e BRO1 PF03097.13 EPX72643.1 - 8.7e-94 314.3 1.2 8.7e-94 314.3 0.8 1.9 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EPX72643.1 - 1.1e-42 146.0 17.9 1.1e-42 146.0 12.4 2.2 1 1 1 2 2 2 1 ALIX V-shaped domain binding to HIV TPR_7 PF13176.1 EPX72643.1 - 0.43 10.4 2.8 19 5.3 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Prenyltrans PF00432.16 EPX72644.1 - 4.4e-39 131.7 14.7 8.6e-11 41.2 0.5 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPX72644.1 - 6.4e-24 84.5 0.2 5.1e-16 59.0 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPX72644.1 - 1.7e-08 34.4 0.2 0.00042 20.2 0.0 3.6 2 1 1 3 3 3 2 Prenyltransferase-like Metallophos PF00149.23 EPX72645.1 - 8.2e-10 38.4 5.5 2.1e-09 37.0 3.8 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cut12 PF11500.3 EPX72645.1 - 0.19 11.3 0.2 0.34 10.6 0.1 1.3 1 0 0 1 1 1 0 Spindle pole body formation-associated protein CorA PF01544.13 EPX72646.1 - 2.6e-50 171.1 0.1 4.1e-50 170.4 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein 14-3-3 PF00244.15 EPX72647.1 - 8.7e-104 345.7 1.0 1e-103 345.5 0.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1900 PF08954.6 EPX72647.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1900) SNF2_N PF00176.18 EPX72648.1 - 7.2e-74 248.2 0.9 1.2e-73 247.4 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPX72648.1 - 1.8e-11 43.7 0.1 1.3e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EPX72648.1 - 3.6e-08 32.9 4.0 6.7e-08 32.0 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPX72648.1 - 6.9e-08 32.1 7.1 1.7e-07 30.9 5.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPX72648.1 - 2e-07 30.8 7.8 4.5e-07 29.7 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX72648.1 - 6.1e-06 25.8 5.4 1.2e-05 24.8 3.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 EPX72648.1 - 4.9e-05 22.8 0.6 0.00014 21.3 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 EPX72648.1 - 0.00031 20.3 6.9 0.00067 19.2 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPX72648.1 - 0.03 14.2 9.2 0.082 12.7 6.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 EPX72648.1 - 0.053 13.2 6.1 0.016 14.9 1.7 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 EPX72648.1 - 0.12 11.9 3.0 0.29 10.7 2.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 EPX72648.1 - 0.18 11.3 4.2 0.47 10.0 2.9 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EPX72648.1 - 0.31 10.8 4.8 1.1 9.0 3.3 2.1 1 0 0 1 1 1 0 RING-type zinc-finger RRM_1 PF00076.17 EPX72649.1 - 2e-37 126.6 0.0 3.6e-16 58.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX72649.1 - 9.1e-23 79.8 0.0 2.4e-10 40.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX72649.1 - 1.4e-21 76.2 0.0 1.2e-09 38.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPX72649.1 - 0.00019 21.1 0.0 0.0031 17.2 0.0 2.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EPX72649.1 - 0.0011 18.7 0.0 0.0058 16.4 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Laminin_G_1 PF00054.18 EPX72649.1 - 0.075 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain TRAM PF01938.15 EPX72649.1 - 0.18 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 TRAM domain NTR2 PF15458.1 EPX72650.1 - 3.3e-24 85.5 20.3 3.3e-24 85.5 14.1 2.0 2 0 0 2 2 2 1 Nineteen complex-related protein 2 DUF3896 PF13035.1 EPX72650.1 - 1.9 8.5 5.5 0.79 9.8 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Vps8 PF12816.2 EPX72652.1 - 1.1e-33 116.1 9.1 7e-33 113.5 2.2 2.7 2 0 0 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 WD40 PF00400.27 EPX72652.1 - 0.0014 18.4 0.4 0.01 15.7 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat FAD_binding_2 PF00890.19 EPX72653.1 - 4.4e-74 249.8 0.0 5.1e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EPX72653.1 - 3.2e-07 30.4 0.0 0.008 16.0 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPX72653.1 - 2.9e-06 26.4 0.1 0.00024 20.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPX72653.1 - 1.2e-05 25.2 0.8 4.3e-05 23.4 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPX72653.1 - 3.5e-05 23.9 0.1 7e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPX72653.1 - 7.2e-05 21.4 8.1 0.0019 16.7 0.8 2.5 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 EPX72653.1 - 0.00071 18.5 3.2 0.0039 16.0 0.1 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 EPX72653.1 - 0.0015 17.6 0.9 0.012 14.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EPX72653.1 - 0.0044 16.1 0.1 0.0069 15.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPX72653.1 - 0.0089 15.1 0.5 0.015 14.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EPX72653.1 - 0.037 13.8 0.1 0.38 10.5 0.1 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EPX72653.1 - 0.047 13.2 0.1 0.087 12.3 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TPR_11 PF13414.1 EPX72654.1 - 1.5e-14 53.3 2.2 7.8e-13 47.8 0.2 2.5 1 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EPX72654.1 - 1.5e-10 40.1 3.5 0.0067 15.9 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPX72654.1 - 5.8e-08 32.9 1.1 3.8e-06 27.1 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPX72654.1 - 1.9e-06 27.3 4.0 0.086 12.7 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3808 PF10300.4 EPX72654.1 - 0.00011 20.8 0.4 0.00014 20.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.1 EPX72654.1 - 0.00012 22.5 1.8 0.014 16.0 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPX72654.1 - 0.00013 21.8 3.0 0.18 11.7 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EPX72654.1 - 0.0014 18.6 4.3 0.0044 17.1 2.6 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EPX72654.1 - 0.0015 18.1 0.4 0.59 10.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPX72654.1 - 0.0017 17.9 3.1 1.1 9.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPX72654.1 - 0.025 14.7 0.0 0.078 13.2 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EPX72654.1 - 0.026 13.7 0.1 0.046 12.9 0.1 1.4 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_6 PF13174.1 EPX72654.1 - 0.16 12.5 0.7 23 5.7 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 EPX72654.1 - 0.33 10.7 3.1 0.92 9.3 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat vATP-synt_AC39 PF01992.11 EPX72655.1 - 2.5e-97 326.0 0.0 2.8e-97 325.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TRAM_LAG1_CLN8 PF03798.11 EPX72656.1 - 4.9e-38 130.6 16.5 7.4e-38 130.0 11.4 1.3 1 0 0 1 1 1 1 TLC domain Ni_hydr_CYTB PF01292.15 EPX72656.1 - 0.0078 15.6 1.5 0.0078 15.6 1.0 2.1 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 PgaD PF13994.1 EPX72656.1 - 3.3 7.1 7.2 1.3 8.4 0.7 2.7 2 1 1 3 3 3 0 PgaD-like protein MFS_1 PF07690.11 EPX72657.1 - 1.3e-29 103.0 25.3 1.3e-29 103.0 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX72657.1 - 3.2e-08 32.5 28.1 2.1e-07 29.8 19.6 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.20 EPX72658.1 - 0.0091 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EPX72659.1 - 8.3e-19 65.9 8.4 0.00072 19.4 0.0 9.1 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 EPX72659.1 - 4e-14 52.6 10.8 3.1e-06 27.5 0.0 8.3 9 2 1 10 10 10 3 HEAT-like repeat IBN_N PF03810.14 EPX72659.1 - 1.7e-13 50.2 2.8 2.9e-13 49.5 0.5 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EPX72659.1 - 2.1e-13 50.3 6.6 4.1e-07 30.2 0.0 6.1 4 2 1 6 6 6 2 HEAT repeats Arm PF00514.18 EPX72659.1 - 0.00019 21.0 6.0 2.4 8.0 0.1 5.9 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EPX72659.1 - 0.00078 18.8 2.4 0.74 9.1 0.1 4.0 3 2 0 4 4 4 1 CLASP N terminal TIP120 PF08623.5 EPX72659.1 - 0.023 14.2 0.7 1.5 8.3 0.0 4.0 4 1 1 5 5 5 0 TATA-binding protein interacting (TIP20) UME PF08064.8 EPX72659.1 - 0.12 12.3 5.2 2.3 8.2 0.4 4.3 3 1 2 5 5 5 0 UME (NUC010) domain NAD_kinase PF01513.16 EPX72660.1 - 1e-80 270.5 0.0 1.4e-80 270.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase zf-C2H2 PF00096.21 EPX72661.1 - 0.00022 21.3 1.3 0.00022 21.3 0.9 3.7 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPX72661.1 - 0.00087 19.1 0.3 0.00087 19.1 0.2 2.4 2 1 0 2 2 2 1 C2H2-type zinc finger DUF3505 PF12013.3 EPX72661.1 - 0.059 13.6 2.6 5.4 7.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) zf-C2H2_jaz PF12171.3 EPX72661.1 - 0.48 10.6 4.0 0.53 10.4 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding BAT2_N PF07001.6 EPX72661.1 - 3.8 7.8 13.7 1.7 8.9 2.4 3.1 3 0 0 3 3 3 0 BAT2 N-terminus Ligase_CoA PF00549.14 EPX72663.1 - 8.7e-27 93.5 0.1 1.6e-26 92.7 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 EPX72663.1 - 5.5e-25 87.7 2.0 6.7e-24 84.2 0.4 2.4 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 EPX72663.1 - 1.1e-08 34.7 0.0 2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EPX72663.1 - 0.0072 16.4 0.0 0.019 15.1 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain TFIIB PF00382.14 EPX72664.1 - 1.1e-43 146.8 0.3 2.3e-24 84.9 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EPX72664.1 - 2.5e-13 49.0 1.7 4.1e-13 48.4 1.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_27 PF13463.1 EPX72664.1 - 0.038 14.3 0.0 19 5.6 0.0 3.1 2 1 0 2 2 2 0 Winged helix DNA-binding domain Cyclin_N PF00134.18 EPX72664.1 - 0.042 13.4 0.1 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 Cyclin, N-terminal domain HTH_23 PF13384.1 EPX72664.1 - 0.043 13.4 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_5 PF01022.15 EPX72664.1 - 0.058 13.0 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Sigma70_r4_2 PF08281.7 EPX72664.1 - 0.061 12.7 0.0 0.18 11.2 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.18 EPX72664.1 - 0.11 12.1 0.1 0.34 10.5 0.1 1.9 1 0 0 1 1 1 0 MerR family regulatory protein TrmB PF01978.14 EPX72664.1 - 0.12 12.1 0.0 16 5.2 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF2296 PF10058.4 EPX72664.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) IF4E PF01652.13 EPX72665.1 - 5.1e-54 182.2 0.1 6.3e-54 181.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Methyltransf_PK PF05891.7 EPX72666.1 - 2.8e-87 291.6 0.0 3.1e-87 291.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 EPX72666.1 - 1.4e-05 25.6 0.0 2.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX72666.1 - 2.4e-05 24.7 0.0 5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX72666.1 - 5.3e-05 23.5 0.0 0.0001 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain BRAP2 PF07576.7 EPX72667.1 - 2.3e-29 101.1 0.0 1.6e-28 98.4 0.0 2.3 2 0 0 2 2 2 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EPX72667.1 - 6.2e-19 67.8 11.8 6.2e-19 67.8 8.2 1.9 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EPX72667.1 - 1e-08 34.8 9.8 1e-08 34.8 6.8 2.3 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPX72667.1 - 0.00018 21.4 9.7 0.00018 21.4 6.7 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPX72667.1 - 0.00024 21.1 5.7 0.00024 21.1 4.0 2.4 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPX72667.1 - 0.00044 19.8 9.1 0.00044 19.8 6.3 2.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ADIP PF11559.3 EPX72667.1 - 0.17 11.7 18.7 1.9 8.4 5.9 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EPX72667.1 - 0.35 10.4 19.6 61 3.1 13.6 2.3 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 EPX72667.1 - 0.48 9.9 9.8 3.9 7.0 1.3 2.7 2 0 0 2 2 2 0 Septum formation initiator zf-RING_UBOX PF13445.1 EPX72667.1 - 0.79 9.4 11.2 0.3 10.8 2.1 2.7 2 0 0 2 2 2 0 RING-type zinc-finger CENP-Q PF13094.1 EPX72667.1 - 0.8 9.7 16.3 1.2 9.1 10.6 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2968 PF11180.3 EPX72667.1 - 1.4 8.2 11.4 3.1 7.1 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF3450 PF11932.3 EPX72667.1 - 2.6 7.2 14.0 0.37 10.0 6.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SlyX PF04102.7 EPX72667.1 - 5.7 7.3 12.4 4.6 7.6 1.1 3.1 2 1 1 3 3 3 0 SlyX DUF1664 PF07889.7 EPX72667.1 - 6.2 6.6 10.0 6.1 6.6 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 EPX72667.1 - 7.4 6.4 8.3 6.3 6.7 1.8 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ING PF12998.2 EPX72668.1 - 0.00061 20.0 1.1 0.00095 19.4 0.8 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Flu_M1_C PF08289.6 EPX72668.1 - 0.02 14.9 0.3 0.036 14.0 0.2 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain RIC3 PF15361.1 EPX72668.1 - 0.24 11.6 2.5 0.17 12.1 0.5 1.6 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 BSD PF03909.12 EPX72669.1 - 1.1e-24 85.9 0.8 1.7e-11 43.6 0.0 3.3 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EPX72669.1 - 1.4e-12 47.0 0.1 5.6e-12 45.1 0.0 2.0 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Ribosomal_S7 PF00177.16 EPX72670.1 - 8.5e-35 119.5 1.0 1.3e-34 118.9 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e PH_10 PF15411.1 EPX72671.1 - 3e-38 130.5 0.0 6.3e-38 129.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EPX72671.1 - 1.6e-37 129.1 2.4 3.6e-37 127.9 1.7 1.7 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 EPX72671.1 - 3.2e-29 100.8 0.1 7.6e-29 99.6 0.0 1.7 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 EPX72671.1 - 1.7e-17 62.8 0.3 4.7e-17 61.4 0.2 1.9 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 EPX72671.1 - 0.013 15.7 0.1 0.03 14.5 0.1 1.6 1 0 0 1 1 1 0 PH domain Sec34 PF04136.10 EPX72672.1 - 0.03 14.0 1.7 0.057 13.1 1.0 1.6 1 1 0 1 1 1 0 Sec34-like family Kdo PF06293.9 EPX72672.1 - 0.046 12.7 0.2 0.47 9.4 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pro_dh PF01619.13 EPX72672.1 - 0.16 10.8 1.0 0.24 10.3 0.7 1.2 1 0 0 1 1 1 0 Proline dehydrogenase V_ATPase_I PF01496.14 EPX72673.1 - 6.3e-287 953.5 10.4 7.2e-287 953.3 7.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family RRM_1 PF00076.17 EPX72674.1 - 2.7e-22 78.1 0.3 1.6e-15 56.4 0.0 3.8 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX72674.1 - 1.3e-15 57.1 0.1 1.3e-10 41.0 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX72674.1 - 3.1e-13 49.3 0.1 3e-05 23.7 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPX72674.1 - 0.0096 15.6 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif CDC45 PF02724.9 EPX72674.1 - 0.43 8.5 18.3 0.67 7.9 12.7 1.3 1 0 0 1 1 1 0 CDC45-like protein LMBR1 PF04791.11 EPX72674.1 - 0.84 8.1 8.6 0.98 7.9 6.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CM_2 PF01817.16 EPX72676.1 - 1.4e-09 37.9 0.3 1.9e-07 31.0 0.0 3.3 2 1 0 2 2 2 1 Chorismate mutase type II DUF2778 PF10908.3 EPX72676.1 - 0.083 13.1 0.0 0.65 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2778) DUF962 PF06127.6 EPX72677.1 - 2.1e-09 37.1 0.2 3.4e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SHD1 PF03983.7 EPX72678.1 - 4.7e-32 109.4 0.2 8.7e-32 108.5 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EPX72678.1 - 2.1e-27 94.4 3.3 4.1e-10 39.0 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.23 EPX72678.1 - 7.7e-23 79.6 6.1 1e-10 40.7 0.0 4.9 5 0 0 5 5 5 3 SH3 domain SH3_2 PF07653.12 EPX72678.1 - 2.4e-18 65.3 0.0 5.5e-05 22.5 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.6 EPX72678.1 - 3.1e-07 30.3 69.1 9.7e-07 28.7 22.4 6.5 4 2 1 5 5 5 2 Domain of unknown function (DUF1720) DUF2313 PF10076.4 EPX72678.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) Ribosomal_S7 PF00177.16 EPX72679.1 - 2.7e-40 137.3 0.6 3.3e-40 137.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Mito_carr PF00153.22 EPX72680.1 - 1.7e-70 232.7 0.8 4.6e-25 87.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 EPX72681.1 - 1.6e-16 59.9 31.5 1.6e-16 59.9 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3382 PF11862.3 EPX72681.1 - 0.013 15.4 0.1 0.044 13.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) UPF0370 PF13980.1 EPX72681.1 - 5.3 6.9 8.5 0.85 9.4 0.0 3.3 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0370) TBCC PF07986.7 EPX72682.1 - 1.8e-21 75.7 2.4 3.3e-21 74.9 1.6 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF2370 PF10176.4 EPX72683.1 - 6.2e-56 189.3 1.3 9.1e-54 182.2 0.2 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) DUF4112 PF13430.1 EPX72683.1 - 0.022 14.6 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) TMEM171 PF15471.1 EPX72683.1 - 0.2 10.4 4.5 7.6 5.2 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein family 171 PgaD PF13994.1 EPX72683.1 - 0.21 11.0 0.4 7.9 5.9 0.0 2.2 2 0 0 2 2 2 0 PgaD-like protein UCH PF00443.24 EPX72684.1 - 1.5e-48 165.2 4.6 3e-48 164.2 3.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EPX72684.1 - 1.3e-43 146.2 2.5 2.7e-20 71.5 0.1 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 EPX72684.1 - 1.9e-15 57.0 6.1 2e-07 30.7 1.9 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RRM_1 PF00076.17 EPX72685.1 - 1e-55 185.2 0.0 6.9e-19 67.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX72685.1 - 1.1e-40 137.4 0.0 9.1e-15 54.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX72685.1 - 1.5e-24 85.5 0.1 5.1e-08 32.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPX72685.1 - 0.0011 18.7 0.0 2.5 8.0 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 EPX72685.1 - 0.0048 16.6 0.1 0.98 9.2 0.0 3.2 3 0 0 3 3 3 1 Limkain b1 AAA PF00004.24 EPX72686.1 - 9.2e-39 132.6 0.0 1.9e-38 131.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EPX72686.1 - 3.4e-07 30.0 0.0 6.2e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EPX72686.1 - 4.6e-06 26.7 0.1 0.00012 22.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPX72686.1 - 2.3e-05 23.5 0.0 4.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EPX72686.1 - 8.2e-05 22.3 0.3 0.001 18.8 0.0 3.0 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPX72686.1 - 0.00015 21.8 0.6 0.00081 19.4 0.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 EPX72686.1 - 0.00062 18.6 0.0 0.0011 17.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EPX72686.1 - 0.001 18.9 0.4 0.0031 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EPX72686.1 - 0.0016 18.0 0.3 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EPX72686.1 - 0.0017 17.8 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EPX72686.1 - 0.0033 17.1 0.1 0.02 14.6 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EPX72686.1 - 0.0034 17.2 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EPX72686.1 - 0.0037 17.1 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EPX72686.1 - 0.0041 16.3 0.9 0.0071 15.5 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EPX72686.1 - 0.0046 16.3 0.1 0.082 12.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 EPX72686.1 - 0.0094 14.9 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 EPX72686.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EPX72686.1 - 0.028 14.1 0.0 1.5 8.4 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 EPX72686.1 - 0.028 15.2 0.0 0.086 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPX72686.1 - 0.049 13.9 0.0 0.26 11.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EPX72686.1 - 0.054 13.1 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Guanylate_kin PF00625.16 EPX72686.1 - 0.058 12.8 0.1 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase AAA_28 PF13521.1 EPX72686.1 - 0.066 13.1 0.1 0.25 11.3 0.1 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EPX72686.1 - 0.073 12.5 0.0 0.3 10.5 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 EPX72686.1 - 0.085 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 EPX72686.1 - 0.097 12.9 0.1 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 ABC transporter KaiC PF06745.8 EPX72686.1 - 0.16 11.1 0.1 1.7 7.7 0.0 2.3 1 1 1 2 2 2 0 KaiC Glyco_transf_20 PF00982.16 EPX72687.1 - 9.6e-201 667.3 0.0 1.1e-200 667.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 EPX72687.1 - 0.0018 17.7 0.8 0.67 9.3 0.0 3.6 3 1 0 3 3 3 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPX72687.1 - 0.0077 16.3 0.0 0.029 14.5 0.0 2.1 1 1 1 2 2 2 1 Glycosyl transferases group 1 IBR PF01485.16 EPX72688.1 - 4.5e-21 74.5 46.3 7.2e-11 41.7 4.3 4.7 3 1 1 4 4 4 3 IBR domain zf-C3HC4 PF00097.20 EPX72688.1 - 1.3e-05 24.6 3.5 1.3e-05 24.6 2.4 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPX72688.1 - 0.00066 19.6 5.9 0.00066 19.6 4.1 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPX72688.1 - 0.0035 17.1 4.0 0.0035 17.1 2.8 3.9 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EPX72688.1 - 0.013 15.1 6.3 0.013 15.1 4.3 4.2 3 1 1 4 4 4 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPX72688.1 - 0.068 12.8 34.6 0.073 12.7 2.5 4.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Xpo1 PF08389.7 EPX72689.1 - 5.7e-18 65.2 3.3 2e-17 63.4 1.1 3.0 2 0 0 2 2 2 1 Exportin 1-like protein zf-CCCH PF00642.19 EPX72690.1 - 3e-06 26.7 11.0 0.0043 16.7 1.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Methyltransf_16 PF10294.4 EPX72691.1 - 3e-18 65.8 0.0 4.5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EPX72691.1 - 1.6e-05 24.1 0.0 2.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EPX72691.1 - 8.4e-05 23.1 0.0 0.00019 21.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPX72691.1 - 0.00059 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EPX72691.1 - 0.00078 19.4 0.1 0.0013 18.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX72691.1 - 0.0077 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EPX72691.1 - 0.033 13.7 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.7 EPX72691.1 - 0.047 14.1 0.1 1.8 9.0 0.0 2.8 3 1 0 3 3 3 0 Methyltransferase domain PCMT PF01135.14 EPX72691.1 - 0.057 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Med23 PF11573.3 EPX72691.1 - 0.11 9.7 0.1 0.15 9.4 0.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 23 Seipin PF06775.9 EPX72692.1 - 1e-51 175.2 3.6 1.4e-51 174.8 2.5 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Sdh_cyt PF01127.17 EPX72692.1 - 7.1 6.4 10.4 3.6 7.4 1.1 2.4 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CENP-F_leu_zip PF10473.4 EPX72693.1 - 0.0058 16.4 10.9 0.0058 16.4 7.5 3.1 1 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EPX72693.1 - 0.12 11.5 28.5 0.036 13.2 13.9 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EPX72693.1 - 0.28 10.3 11.7 0.034 13.3 1.9 2.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein HALZ PF02183.13 EPX72693.1 - 1.9 8.2 14.7 1.3 8.7 0.2 3.9 3 1 0 3 3 3 0 Homeobox associated leucine zipper NPV_P10 PF05531.7 EPX72693.1 - 2.6 8.3 8.3 0.58 10.4 1.7 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2681 PF10883.3 EPX72693.1 - 3.6 7.8 10.6 16 5.8 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) PX PF00787.19 EPX72695.1 - 4.6e-18 65.0 2.1 4.6e-18 65.0 1.4 2.9 3 0 0 3 3 3 1 PX domain EspF PF04806.7 EPX72695.1 - 0.091 12.9 1.0 0.21 11.7 0.7 1.6 1 0 0 1 1 1 0 EspF protein repeat BDHCT PF08072.6 EPX72695.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 BDHCT (NUC031) domain Pyr_redox_2 PF07992.9 EPX72696.1 - 1.1e-26 93.9 0.0 1.7e-26 93.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPX72696.1 - 2.7e-11 43.6 0.0 2.6e-10 40.5 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPX72696.1 - 5.5e-07 29.8 0.0 1.5e-05 25.1 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Cullin PF00888.17 EPX72697.1 - 3.9e-127 425.2 12.7 3.9e-127 425.2 8.8 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EPX72697.1 - 2.2e-22 78.6 1.4 7.7e-22 76.9 0.9 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain COX17 PF05051.8 EPX72697.1 - 0.089 12.8 0.0 20 5.3 0.0 2.7 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Na_H_Exchanger PF00999.16 EPX72698.1 - 2.9e-78 263.0 24.4 3.4e-78 262.8 16.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 EPX72698.1 - 0.042 13.1 37.5 0.01 15.1 10.5 3.0 2 1 1 3 3 3 0 Alkali metal cation/H+ antiporter Nha1 C terminus YrhC PF14143.1 EPX72698.1 - 0.1 12.5 0.2 0.1 12.5 0.2 2.9 4 0 0 4 4 4 0 YrhC-like protein Peptidase_M19 PF01244.16 EPX72699.1 - 1.3e-102 343.0 0.0 1.5e-102 342.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) AAA PF00004.24 EPX72700.1 - 2.5e-41 140.9 0.5 2e-40 138.0 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EPX72700.1 - 8.9e-06 25.7 0.0 8e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPX72700.1 - 2.5e-05 24.3 1.3 0.0023 17.9 0.0 2.8 2 2 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 EPX72700.1 - 2.7e-05 23.9 1.4 0.00023 20.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPX72700.1 - 0.00027 21.0 0.7 0.0096 16.0 0.2 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPX72700.1 - 0.00046 19.3 0.0 0.0012 17.9 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EPX72700.1 - 0.0052 16.6 0.0 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EPX72700.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.11 EPX72700.1 - 0.0081 15.4 0.0 0.033 13.4 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EPX72700.1 - 0.012 15.4 0.1 0.031 14.0 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EPX72700.1 - 0.012 14.7 0.1 0.04 13.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EPX72700.1 - 0.023 13.8 0.1 0.097 11.7 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.1 EPX72700.1 - 0.025 14.1 0.0 0.44 10.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 EPX72700.1 - 0.027 13.4 0.0 0.065 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EPX72700.1 - 0.028 14.3 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EPX72700.1 - 0.044 13.1 0.8 0.52 9.6 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EPX72700.1 - 0.044 14.5 0.0 0.13 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EPX72700.1 - 0.071 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPX72700.1 - 0.12 12.5 0.0 0.53 10.4 0.0 2.2 2 0 0 2 2 1 0 RNA helicase PglZ PF08665.7 EPX72700.1 - 0.39 10.3 2.9 4.1 7.0 1.4 2.3 2 0 0 2 2 2 0 PglZ domain DUF4161 PF13722.1 EPX72701.1 - 0.27 11.5 4.5 3.4 7.9 0.1 2.9 2 1 1 3 3 3 0 C-terminal domain on CstA (DUF4161) Kinesin PF00225.18 EPX72702.1 - 3.3e-99 331.7 0.4 3.3e-99 331.7 0.3 2.3 3 1 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 EPX72702.1 - 0.015 14.5 5.4 0.42 9.7 0.1 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Prefoldin_2 PF01920.15 EPX72703.1 - 4.4e-23 81.0 9.5 4.9e-23 80.9 6.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF1732 PF08340.6 EPX72703.1 - 0.0025 17.5 1.3 0.0043 16.8 0.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1732) Bacillus_HBL PF05791.6 EPX72703.1 - 0.0043 16.4 6.5 0.16 11.3 0.8 2.4 1 1 1 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) Prefoldin PF02996.12 EPX72703.1 - 0.0063 16.1 6.7 0.034 13.7 1.1 2.3 1 1 1 2 2 2 1 Prefoldin subunit WXG100 PF06013.7 EPX72703.1 - 0.0063 16.4 1.8 0.79 9.7 0.1 2.4 2 1 0 2 2 2 1 Proteins of 100 residues with WXG Atg14 PF10186.4 EPX72703.1 - 0.018 13.9 4.5 0.026 13.4 3.1 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3453 PF11935.3 EPX72703.1 - 0.019 14.3 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) IncA PF04156.9 EPX72703.1 - 0.021 14.4 7.2 0.54 9.8 0.4 2.0 1 1 1 2 2 2 0 IncA protein DUF812 PF05667.6 EPX72703.1 - 0.034 12.6 7.7 0.056 11.9 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Fib_alpha PF08702.5 EPX72703.1 - 0.058 13.5 6.8 0.092 12.8 0.9 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 EPX72703.1 - 0.066 13.0 3.6 2.8 7.7 2.4 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_3 PF13758.1 EPX72703.1 - 0.096 12.4 5.2 0.3 10.9 3.3 1.9 1 1 0 1 1 1 0 Prefoldin subunit Lzipper-MIP1 PF14389.1 EPX72703.1 - 0.1 12.7 2.2 0.36 10.9 1.5 1.9 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 FTA4 PF13093.1 EPX72703.1 - 0.11 11.9 2.5 0.12 11.7 1.3 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Tektin PF03148.9 EPX72703.1 - 0.11 11.0 6.4 0.55 8.7 1.8 2.0 2 0 0 2 2 2 0 Tektin family Peptidase_S46 PF10459.4 EPX72703.1 - 0.11 10.8 4.7 0.11 10.8 3.3 1.0 1 0 0 1 1 1 0 Peptidase S46 ADIP PF11559.3 EPX72703.1 - 0.12 12.3 8.8 0.39 10.6 3.4 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Cob_adeno_trans PF01923.13 EPX72703.1 - 0.12 12.2 1.7 0.22 11.3 1.1 1.5 1 1 0 1 1 1 0 Cobalamin adenosyltransferase DUF1359 PF07097.6 EPX72703.1 - 0.12 12.4 2.2 2.1 8.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1359) DUF2408 PF10303.4 EPX72703.1 - 0.18 11.9 3.7 0.55 10.3 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Occludin_ELL PF07303.8 EPX72703.1 - 0.22 12.2 2.3 0.34 11.6 1.0 1.6 1 1 1 2 2 2 0 Occludin homology domain ERp29 PF07749.7 EPX72703.1 - 0.27 11.8 2.7 1 10.0 1.6 2.2 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain HR1 PF02185.11 EPX72703.1 - 0.45 10.3 3.6 2 8.2 1.9 2.3 1 1 1 2 2 2 0 Hr1 repeat Spc24 PF08286.6 EPX72703.1 - 0.48 10.1 7.6 3.4 7.3 1.7 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.10 EPX72703.1 - 0.5 9.8 7.0 0.95 8.9 0.5 2.4 2 1 0 2 2 2 0 Septum formation initiator zf-CpG_bind_C PF12269.3 EPX72703.1 - 0.53 9.7 3.6 0.33 10.3 1.2 1.6 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain YgaB PF14182.1 EPX72703.1 - 0.54 10.5 6.8 2.3 8.5 1.8 2.4 1 1 1 2 2 2 0 YgaB-like protein CENP-F_leu_zip PF10473.4 EPX72703.1 - 0.58 10.0 7.5 7.3 6.4 1.3 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.1 EPX72703.1 - 0.7 8.7 8.7 0.44 9.4 2.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1843 PF08898.5 EPX72703.1 - 0.81 9.7 4.9 1.1 9.2 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DivIVA PF05103.8 EPX72703.1 - 0.96 9.5 9.8 2.8 8.0 1.6 2.2 1 1 1 2 2 2 0 DivIVA protein APG6 PF04111.7 EPX72703.1 - 0.98 8.3 8.5 4.2 6.3 5.9 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF4200 PF13863.1 EPX72703.1 - 1.8 8.5 8.3 7.6 6.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) IFP_35_N PF07334.8 EPX72703.1 - 2 8.4 5.0 0.84 9.6 0.2 2.2 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus BLOC1_2 PF10046.4 EPX72703.1 - 2 8.5 6.7 1.5 9.0 0.4 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GrpE PF01025.14 EPX72703.1 - 3 7.3 8.6 1.4 8.4 2.3 2.0 1 1 1 2 2 2 0 GrpE TMF_DNA_bd PF12329.3 EPX72703.1 - 3.3 7.5 8.9 9.6 6.0 1.1 2.5 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 EPX72703.1 - 4.4 7.7 5.7 9.2 6.6 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Med9 PF07544.8 EPX72703.1 - 5 6.9 6.4 15 5.3 1.1 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AAR2 PF05282.6 EPX72704.1 - 6.5e-39 133.8 8.8 4e-38 131.2 6.1 2.0 1 1 0 1 1 1 1 AAR2 protein DUF3579 PF12112.3 EPX72704.1 - 0.056 13.3 0.2 0.46 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3579) 7TM_GPCR_Srb PF02175.11 EPX72704.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srb Ribosomal_S11 PF00411.14 EPX72705.1 - 7.8e-41 138.6 1.3 9.3e-41 138.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 DNA_pol_B PF00136.16 EPX72706.1 - 2.2e-115 386.1 1.6 3e-115 385.6 1.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EPX72706.1 - 3.3e-42 144.4 0.2 6.2e-42 143.5 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 EPX72706.1 - 1e-36 126.0 8.1 2.6e-35 121.4 5.6 2.5 1 1 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.3 EPX72706.1 - 5.1e-23 80.6 13.6 2.7e-22 78.3 7.0 3.0 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Ribosomal_L30_N PF08079.7 EPX72707.1 - 3.5e-21 75.0 19.6 3.5e-21 75.0 13.6 1.7 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EPX72707.1 - 3.9e-21 74.3 0.8 8.8e-21 73.2 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Hydantoinase_B PF02538.9 EPX72708.1 - 7.2e-201 667.9 1.0 1.1e-200 667.3 0.7 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EPX72708.1 - 1.2e-94 316.7 1.9 1.2e-94 316.6 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EPX72708.1 - 1.9e-58 196.8 1.7 3e-57 192.9 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region YpjP PF14005.1 EPX72709.1 - 0.042 13.6 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 YpjP-like protein ORC6 PF05460.8 EPX72709.1 - 1.7 7.6 9.6 2.2 7.2 6.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Fungal_trans PF04082.13 EPX72710.1 - 2.5e-16 59.3 6.0 4.6e-16 58.4 4.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPX72710.1 - 8.7e-09 35.2 15.2 2.3e-05 24.4 0.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPX72710.1 - 5.9e-05 22.8 0.3 5.9e-05 22.8 0.2 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EPX72710.1 - 0.00015 21.8 21.8 0.00089 19.4 0.3 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger Zn_ribbon_2 PF12674.2 EPX72710.1 - 0.017 15.4 0.1 0.04 14.2 0.1 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-C2H2_jaz PF12171.3 EPX72710.1 - 0.044 13.9 6.2 0.06 13.5 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EPX72710.1 - 0.21 11.9 19.0 1.5 9.2 0.3 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.10 EPX72710.1 - 3.5 7.4 20.5 1.3 8.7 7.6 2.8 2 1 1 3 3 3 0 BED zinc finger MFS_1 PF07690.11 EPX72711.1 - 3.7e-40 137.7 18.6 4.7e-40 137.3 12.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3169 PF11368.3 EPX72711.1 - 0.96 8.5 0.0 0.96 8.5 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF3169) DUF1445 PF07286.7 EPX72712.1 - 4.6e-55 185.2 0.0 6.8e-55 184.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) His_Phos_1 PF00300.17 EPX72713.1 - 3.1e-23 82.6 0.0 3.8e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Flavodoxin_2 PF02525.12 EPX72714.1 - 2e-32 112.2 0.0 3.1e-32 111.6 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 EPX72714.1 - 0.0066 15.8 0.5 0.014 14.7 0.3 1.5 1 1 0 1 1 1 1 Flavodoxin FumaraseC_C PF10415.4 EPX72714.1 - 0.026 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Fumarase C C-terminus FMN_red PF03358.10 EPX72714.1 - 0.05 13.0 0.0 0.22 11.0 0.0 1.9 1 1 0 1 1 1 0 NADPH-dependent FMN reductase DUF4146 PF13652.1 EPX72714.1 - 0.051 13.3 0.1 0.08 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4146) Oxidored_FMN PF00724.15 EPX72715.1 - 5.9e-110 367.4 0.0 6.7e-110 367.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fe-ADH PF00465.14 EPX72716.1 - 4.7e-119 397.2 0.3 5.7e-119 397.0 0.2 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EPX72716.1 - 4.5e-22 78.5 0.9 1.4e-19 70.4 0.6 2.2 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Pantoate_ligase PF02569.10 EPX72717.1 - 9.9e-96 319.7 0.0 1.1e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase FAD_syn PF06574.7 EPX72717.1 - 0.0048 16.5 0.0 0.023 14.3 0.0 1.9 2 0 0 2 2 2 1 FAD synthetase Pantoate_transf PF02548.10 EPX72718.1 - 6.4e-104 346.6 0.1 7.2e-104 346.5 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EPX72718.1 - 0.013 14.7 0.2 0.033 13.4 0.1 1.6 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Glyco_transf_8 PF01501.15 EPX72719.1 - 6.8e-14 51.7 0.3 3.1e-13 49.6 0.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EPX72719.1 - 0.012 14.9 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative SNF2_N PF00176.18 EPX72722.1 - 4.4e-71 239.1 0.0 7.8e-71 238.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPX72722.1 - 5.9e-13 48.4 0.0 1.3e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 EPX72722.1 - 4.7e-12 45.7 0.0 1.1e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain DEAD PF00270.24 EPX72722.1 - 5.5e-05 22.7 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 EPX72722.1 - 0.00012 22.0 17.6 0.00024 21.0 12.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX72722.1 - 0.00013 21.6 14.7 0.00026 20.5 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPX72722.1 - 0.00026 20.7 16.0 0.00053 19.7 11.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPX72722.1 - 0.00084 18.9 17.7 0.0017 17.9 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPX72722.1 - 0.0092 15.8 16.5 0.02 14.7 11.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EPX72722.1 - 0.018 14.7 16.0 0.038 13.7 11.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPX72722.1 - 0.025 14.2 11.8 0.074 12.7 8.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger UBA_4 PF14555.1 EPX72722.1 - 0.044 13.3 0.2 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain DUF3645 PF12359.3 EPX72722.1 - 0.11 11.6 0.0 0.27 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) Ribosomal_S3Ae PF01015.13 EPX72723.1 - 9.5e-79 263.2 3.2 1.1e-78 263.0 2.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family ATP-synt_10 PF05176.9 EPX72723.1 - 0.042 13.1 0.3 0.18 11.0 0.2 1.9 1 1 0 1 1 1 0 ATP10 protein Phosphodiest PF01663.17 EPX72724.1 - 6.3e-17 61.9 4.0 9.1e-13 48.2 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EPX72724.1 - 0.00011 21.5 0.1 0.079 12.1 0.0 2.3 1 1 1 2 2 2 2 Sulfatase TRAPP PF04051.11 EPX72725.1 - 1.8e-34 118.4 0.0 2.3e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component zf-Tim10_DDP PF02953.10 EPX72726.1 - 5.1e-19 67.3 3.7 6.2e-19 67.0 2.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Toxin_2 PF00451.14 EPX72726.1 - 1.1 9.3 4.2 2 8.5 0.2 2.1 1 1 1 2 2 2 0 Scorpion short toxin, BmKK2 GDC-P PF02347.11 EPX72727.1 - 3.1e-198 658.7 0.0 9.1e-185 614.3 0.0 2.8 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EPX72727.1 - 1.4e-05 24.0 0.1 0.00077 18.2 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPX72727.1 - 0.00022 20.4 0.0 0.00044 19.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EPX72727.1 - 0.039 12.2 0.1 0.07 11.3 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Ribosomal_S6e PF01092.14 EPX72728.1 - 2.4e-64 214.6 0.1 5.4e-64 213.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e MFS_1 PF07690.11 EPX72729.1 - 2.6e-22 79.0 35.2 2.6e-22 79.0 24.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX72729.1 - 1.1e-05 24.2 13.6 1.1e-05 24.2 9.4 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter WD40 PF00400.27 EPX72730.1 - 1e-20 72.7 9.7 7.3e-07 28.8 0.0 7.2 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EPX72730.1 - 1e-07 31.8 1.0 1.4e-05 24.8 0.6 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PDCD2_C PF04194.8 EPX72731.1 - 6.7e-33 113.6 0.1 1.7e-32 112.2 0.0 1.6 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Glyco_hydro_cc PF11790.3 EPX72732.1 - 2.9e-55 187.3 0.4 4.2e-55 186.7 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core GHMP_kinases_N PF00288.21 EPX72733.1 - 3.5e-20 71.8 0.1 1e-19 70.3 0.1 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPX72733.1 - 3.5e-05 23.8 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EPX72733.1 - 0.0051 16.0 0.0 0.0086 15.3 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature DUF2366 PF10171.4 EPX72733.1 - 0.089 12.2 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2366) Chitin_synth_1 PF01644.12 EPX72734.1 - 2.2e-85 284.4 0.2 3.3e-85 283.8 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EPX72734.1 - 3.9e-29 101.4 1.1 6.3e-21 74.3 0.1 3.0 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 EPX72734.1 - 1.8e-28 98.0 0.1 4.6e-28 96.7 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EPX72734.1 - 4.8e-08 32.9 9.2 4.8e-08 32.9 6.4 3.0 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPX72734.1 - 3.4e-07 30.2 0.0 2e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 NUDIX PF00293.23 EPX72735.1 - 1e-14 54.3 0.2 2.3e-14 53.1 0.1 1.7 1 1 0 1 1 1 1 NUDIX domain S6PP_C PF08472.5 EPX72735.1 - 0.093 12.3 0.1 0.45 10.1 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal HAD_2 PF13419.1 EPX72736.1 - 6.3e-30 104.6 0.8 8.2e-30 104.3 0.6 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPX72736.1 - 4.9e-05 23.8 0.0 0.00021 21.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPX72736.1 - 0.00024 20.7 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EPX72736.1 - 0.01 15.4 0.0 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase NIF PF03031.13 EPX72736.1 - 0.026 14.1 0.1 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Y_phosphatase3C PF13348.1 EPX72736.1 - 0.086 12.9 0.9 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family C-terminal region Calcipressin PF04847.7 EPX72737.1 - 1.4e-31 109.5 0.0 1.4e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Calcipressin Pkinase PF00069.20 EPX72738.1 - 4.2e-72 242.4 0.0 5e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72738.1 - 9e-32 110.1 0.0 1.1e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPX72738.1 - 8.8e-05 21.6 0.1 0.00036 19.6 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX72738.1 - 0.00061 19.6 0.1 0.0021 17.8 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPX72738.1 - 0.0097 14.9 0.0 0.28 10.1 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EPX72738.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family ApbA PF02558.11 EPX72739.1 - 8.7e-08 31.7 0.0 1.5e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EPX72739.1 - 5.9e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal COPIIcoated_ERV PF07970.7 EPX72740.1 - 9.8e-66 221.5 0.2 1.3e-65 221.0 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EPX72740.1 - 6e-32 109.4 0.3 2e-31 107.8 0.0 2.0 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MPC PF03650.8 EPX72741.1 - 3.7e-47 159.2 2.0 3.9e-47 159.1 1.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Sel1 PF08238.7 EPX72742.1 - 1.6e-40 136.6 12.1 2.4e-08 34.3 0.3 7.7 8 0 0 8 8 8 6 Sel1 repeat DUF249 PF03158.8 EPX72742.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Multigene family 530 protein TPR_6 PF13174.1 EPX72742.1 - 0.7 10.4 3.0 31 5.2 0.9 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 EPX72743.1 - 5.3e-60 202.7 0.1 4.1e-59 199.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72743.1 - 5e-28 97.8 0.1 2.4e-20 72.6 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EPX72743.1 - 3.1e-05 24.3 1.1 3.1e-05 24.3 0.8 1.8 2 0 0 2 2 2 1 Protein kinase C terminal domain APH PF01636.18 EPX72743.1 - 0.00043 20.1 0.1 1.1 8.9 0.0 2.7 1 1 2 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EPX72743.1 - 0.00098 18.1 0.1 0.035 13.0 0.0 2.5 2 0 0 2 2 2 1 Kinase-like DUF1374 PF07118.6 EPX72743.1 - 0.08 13.0 0.2 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) E1-E2_ATPase PF00122.15 EPX72744.1 - 5.9e-14 51.6 0.0 1.5e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EPX72744.1 - 1.5e-13 51.3 0.0 3.5e-13 50.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPX72744.1 - 6e-10 39.8 0.5 2.5e-08 34.6 0.3 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPX72744.1 - 7e-10 38.7 0.0 2.7e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPX72744.1 - 0.0039 16.8 0.3 0.0091 15.5 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Porphobil_deam PF01379.15 EPX72745.1 - 3.9e-81 271.0 0.0 5e-81 270.7 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EPX72745.1 - 1.3e-18 66.8 0.0 2.2e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain WD40 PF00400.27 EPX72746.1 - 1.5e-59 195.8 20.8 1.6e-14 53.0 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ParA PF10609.4 EPX72746.1 - 2.3e-37 126.7 0.1 4.7e-37 125.7 0.1 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EPX72746.1 - 1.7e-11 43.9 0.0 3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain eIF2A PF08662.6 EPX72746.1 - 4.2e-06 26.6 0.0 0.0015 18.2 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EPX72746.1 - 0.00019 19.4 0.8 0.15 9.8 0.1 2.2 2 0 0 2 2 2 2 IKI3 family ArsA_ATPase PF02374.10 EPX72746.1 - 0.00056 19.0 0.1 0.0096 14.9 0.1 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EPX72746.1 - 0.0031 16.6 0.0 0.014 14.5 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ Apc4_WD40 PF12894.2 EPX72746.1 - 0.0037 16.7 0.0 0.96 9.0 0.0 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_25 PF13481.1 EPX72746.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EPX72746.1 - 0.019 14.9 0.0 0.058 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_26 PF13500.1 EPX72746.1 - 0.025 14.1 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EPX72746.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EPX72746.1 - 0.086 12.0 0.1 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 zf-C4_ClpX PF06689.8 EPX72746.1 - 0.35 10.4 2.7 0.98 8.9 1.8 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger Ribosomal_S26e PF01283.14 EPX72747.1 - 7.5e-52 174.3 9.2 8.4e-52 174.2 6.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Ribosomal_L14e PF01929.12 EPX72748.1 - 2e-26 92.1 1.0 2e-26 92.1 0.7 1.4 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.24 EPX72748.1 - 0.00026 20.5 1.6 0.00046 19.7 1.1 1.4 1 0 0 1 1 1 1 KOW motif Complex1_LYR PF05347.10 EPX72749.1 - 9.4e-05 22.1 0.1 0.00022 20.9 0.0 1.8 1 1 0 1 1 1 1 Complex 1 protein (LYR family) CTP_transf_2 PF01467.21 EPX72750.1 - 3.2e-31 108.4 0.0 4.4e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase TALPID3 PF15324.1 EPX72750.1 - 0.11 9.8 5.4 0.13 9.5 3.7 1.0 1 0 0 1 1 1 0 Hedgehog signalling target DEAD PF00270.24 EPX72751.1 - 5.6e-43 146.3 0.3 1.1e-42 145.3 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX72751.1 - 4.6e-30 103.2 0.1 1.5e-29 101.6 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EPX72751.1 - 0.00048 19.8 0.2 0.0015 18.2 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain Helicase_C_2 PF13307.1 EPX72751.1 - 0.0054 16.6 0.0 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 Helicase C-terminal domain DUF1253 PF06862.7 EPX72751.1 - 0.013 13.9 0.0 0.099 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_30 PF13604.1 EPX72751.1 - 0.02 14.4 0.3 0.061 12.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EPX72751.1 - 0.025 14.7 0.6 0.17 12.0 0.4 2.2 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 EPX72751.1 - 0.065 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) ResIII PF04851.10 EPX72751.1 - 0.099 12.4 0.0 0.25 11.1 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit FAT PF02259.18 EPX72752.1 - 2.1e-68 230.9 8.3 4.3e-68 229.8 5.8 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EPX72752.1 - 4.6e-28 98.2 0.5 1.4e-27 96.6 0.4 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EPX72752.1 - 1.3e-11 43.7 1.9 1.8e-09 36.8 0.8 2.7 2 0 0 2 2 2 2 FATC domain TPR_11 PF13414.1 EPX72752.1 - 0.13 11.9 3.5 0.26 10.9 0.3 3.0 2 1 1 3 3 3 0 TPR repeat TrkH PF02386.11 EPX72753.1 - 9.4e-94 313.8 11.1 3.2e-91 305.5 6.6 2.8 2 1 0 2 2 2 2 Cation transport protein ELO PF01151.13 EPX72754.1 - 3.4e-51 173.9 20.4 4.4e-51 173.6 14.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family NDK PF00334.14 EPX72755.1 - 1.7e-55 186.4 0.0 2e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase GCP5-Mod21 PF14609.1 EPX72756.1 - 6.1e-33 113.8 9.7 2.1e-31 108.7 6.7 2.1 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Pkinase PF00069.20 EPX72757.1 - 3.3e-72 242.7 0.4 6.3e-72 241.8 0.3 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72757.1 - 5.8e-57 192.7 0.2 9.1e-57 192.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EPX72757.1 - 2e-10 40.7 3.4 2e-10 40.7 2.3 2.6 2 1 0 2 2 2 1 PH domain PBD PF00786.23 EPX72757.1 - 4.5e-10 39.7 0.6 2.3e-09 37.5 0.1 2.6 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EPX72757.1 - 1.5e-09 37.2 0.0 3.6e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPX72757.1 - 0.00018 20.6 1.1 0.00035 19.6 0.8 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX72757.1 - 0.0028 17.4 0.0 0.01 15.6 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family PH_11 PF15413.1 EPX72757.1 - 0.006 16.8 3.1 0.023 14.9 1.4 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain Mid1 PF12929.2 EPX72758.1 - 2.8e-107 359.1 19.1 3.8e-107 358.6 13.2 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component PP2 PF14299.1 EPX72758.1 - 0.023 14.0 0.1 0.051 12.9 0.1 1.6 1 0 0 1 1 1 0 Phloem protein 2 Fz PF01392.17 EPX72758.1 - 0.033 14.5 2.2 0.81 10.0 0.2 2.6 2 0 0 2 2 2 0 Fz domain Amino_oxidase PF01593.19 EPX72759.1 - 6.7e-18 64.9 0.0 1.5e-17 63.8 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPX72759.1 - 1.2e-09 38.0 0.0 6.6e-09 35.6 0.0 2.2 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPX72759.1 - 8.2e-06 24.9 0.0 2.1e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPX72759.1 - 0.035 13.9 0.0 0.63 9.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPX72759.1 - 0.059 12.4 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HSP70 PF00012.15 EPX72760.1 - 2.1e-60 204.3 0.0 2.1e-60 204.3 0.0 2.5 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EPX72760.1 - 0.083 11.4 0.1 0.33 9.4 0.0 2.0 1 1 0 1 1 1 0 MreB/Mbl protein Mit_ribos_Mrp51 PF11709.3 EPX72760.1 - 0.32 10.1 9.4 0.73 8.9 6.1 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit Mso1_Sec1_bdg PF14475.1 EPX72761.1 - 7.9e-12 44.3 0.0 1.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Axin_b-cat_bind PF08833.5 EPX72761.1 - 0.0027 17.3 0.1 0.0027 17.3 0.1 2.6 2 1 0 2 2 2 1 Axin beta-catenin binding domain Mso1_C PF14477.1 EPX72761.1 - 0.016 15.5 8.0 0.016 15.5 5.5 2.1 3 0 0 3 3 3 0 Membrane-polarising domain of Mso1 FH2 PF02181.18 EPX72762.1 - 2.9e-78 263.3 3.3 1.2e-77 261.3 2.3 2.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EPX72762.1 - 3.1e-22 78.9 4.5 3.1e-22 78.9 3.1 3.4 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EPX72762.1 - 7e-12 45.0 0.0 7e-12 45.0 0.0 4.2 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain SlyX PF04102.7 EPX72762.1 - 0.29 11.5 8.0 0.89 9.9 2.4 4.1 4 0 0 4 4 4 0 SlyX DAO PF01266.19 EPX72763.1 - 3e-45 154.7 0.0 3.4e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPX72763.1 - 0.00033 20.4 0.0 0.0021 17.8 0.0 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EPX72763.1 - 0.0062 16.5 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPX72763.1 - 0.015 15.2 0.1 0.58 9.9 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPX72763.1 - 0.13 12.2 0.0 1.4 8.9 0.0 2.5 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.15 EPX72764.1 - 1.5e-66 220.6 3.1 2.1e-30 104.4 0.0 4.0 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EPX72764.1 - 2.2e-41 141.6 7.4 1.2e-26 93.6 0.4 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EPX72764.1 - 2.1e-12 46.8 0.2 3.6e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EPX72764.1 - 5.9e-12 45.7 2.6 0.00023 21.3 0.0 4.6 3 2 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPX72764.1 - 2.1e-11 43.7 3.5 2e-05 24.5 0.1 4.9 4 2 1 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.16 EPX72764.1 - 8.1e-09 35.2 2.2 0.0037 16.9 0.0 3.3 2 1 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.12 EPX72764.1 - 9.9e-09 34.4 5.4 4e-08 32.4 0.5 2.2 1 1 1 2 2 2 1 Calsequestrin Redoxin PF08534.5 EPX72764.1 - 1.1e-07 31.4 2.5 0.001 18.6 0.0 3.4 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 EPX72764.1 - 0.00054 19.7 0.2 0.056 13.2 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.1 EPX72764.1 - 0.0054 16.7 4.8 0.017 15.1 0.7 3.3 3 2 1 4 4 4 1 Thioredoxin HyaE PF07449.6 EPX72764.1 - 0.018 14.9 0.1 1.7 8.5 0.0 3.5 4 0 0 4 4 4 0 Hydrogenase-1 expression protein HyaE DSBA PF01323.15 EPX72764.1 - 0.063 12.8 0.0 6.9 6.1 0.0 2.6 2 1 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.1 EPX72764.1 - 0.51 9.9 4.7 8.3 5.9 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin DUF3384 PF11864.3 EPX72765.1 - 2.4e-52 177.9 20.6 4e-52 177.2 14.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) WD40 PF00400.27 EPX72766.1 - 1e-70 231.2 15.3 4.3e-12 45.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EPX72766.1 - 2.2e-17 62.9 4.3 4.2e-17 62.0 2.9 1.5 1 0 0 1 1 1 1 Tup N-terminal eIF2A PF08662.6 EPX72766.1 - 8.5e-08 32.1 0.0 3.8e-05 23.4 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPX72766.1 - 1.4e-07 30.0 1.7 0.074 11.1 0.0 4.8 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPX72766.1 - 1.9e-06 26.9 9.9 0.017 13.8 0.0 5.1 2 1 1 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 EPX72766.1 - 7.2e-05 22.3 0.8 1.3 8.8 0.0 5.3 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EPX72766.1 - 0.00091 17.6 0.1 0.1 10.8 0.0 2.7 2 1 0 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 EPX72766.1 - 0.0091 15.4 0.0 0.16 11.3 0.0 2.5 3 0 0 3 3 3 1 PQQ-like domain FliJ PF02050.11 EPX72766.1 - 0.053 13.5 1.5 0.11 12.6 1.0 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein Vps16_N PF04841.8 EPX72766.1 - 0.11 10.9 0.0 0.26 9.7 0.0 1.6 1 0 0 1 1 1 0 Vps16, N-terminal region Proteasome_A_N PF10584.4 EPX72766.1 - 3.5 7.0 5.1 12 5.3 0.1 2.9 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature UPF0139 PF03669.8 EPX72767.1 - 5.8e-09 35.4 0.2 7.5e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) UQ_con PF00179.21 EPX72768.1 - 1e-50 170.8 0.0 1.1e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPX72768.1 - 1.9e-06 27.6 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPX72768.1 - 0.023 14.6 0.1 0.032 14.1 0.1 1.5 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 EPX72768.1 - 0.052 13.2 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain Sas10_Utp3 PF04000.10 EPX72769.1 - 1.6e-07 31.3 1.6 1.6e-07 31.3 1.1 2.6 3 0 0 3 3 3 1 Sas10/Utp3/C1D family CDV3 PF15359.1 EPX72769.1 - 0.00025 21.1 0.2 0.00049 20.1 0.1 1.5 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 FCH PF00611.18 EPX72769.1 - 0.13 12.5 2.5 0.26 11.4 0.3 2.4 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Mannosyl_trans2 PF04188.8 EPX72770.1 - 9.9e-85 285.0 46.8 1.8e-83 280.9 32.4 1.9 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) EF-hand_1 PF00036.27 EPX72771.1 - 4e-25 85.1 9.9 1.7e-07 30.0 0.1 5.0 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 EPX72771.1 - 1.4e-23 80.5 3.5 1.1e-06 28.0 0.1 4.9 4 1 2 6 6 6 4 EF-hand domain EF-hand_7 PF13499.1 EPX72771.1 - 3e-22 78.5 3.2 8.3e-14 51.4 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPX72771.1 - 1.3e-17 62.2 7.7 4.5e-06 25.7 0.1 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EPX72771.1 - 1e-14 53.8 9.5 4.4e-06 26.1 0.6 4.3 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EPX72771.1 - 2.8e-08 33.4 7.5 0.37 10.5 0.1 4.1 1 1 3 4 4 4 4 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EPX72771.1 - 8.3e-05 22.4 0.9 0.024 14.5 0.0 3.3 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EPX72771.1 - 0.00057 19.8 2.7 0.065 13.2 0.1 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 EPX72771.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Plectin/S10 domain EF-hand_10 PF14788.1 EPX72771.1 - 0.003 17.1 3.6 9.1 6.0 0.0 3.9 3 1 0 3 3 3 1 EF hand EF-hand_2 PF09068.6 EPX72771.1 - 0.018 15.0 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 EF hand DUF1679 PF07914.6 EPX72771.1 - 0.041 12.5 0.4 3.1 6.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) SAC3_GANP PF03399.11 EPX72771.1 - 0.08 12.4 0.0 0.3 10.6 0.0 1.9 1 1 1 2 2 2 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Pam16 PF03656.8 EPX72771.1 - 0.87 9.3 3.5 7.9 6.2 0.1 3.0 2 1 0 2 2 2 0 Pam16 PseudoU_synth_2 PF00849.17 EPX72772.1 - 1.1e-30 106.5 0.0 1.7e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF2863 PF11062.3 EPX72772.1 - 0.042 11.9 0.0 0.063 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) Auto_anti-p27 PF06677.7 EPX72772.1 - 0.062 13.0 0.1 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) XPG_N PF00752.12 EPX72773.1 - 2.5e-15 56.5 0.1 1.1e-14 54.4 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 EPX72773.1 - 4.5e-14 52.2 0.1 1.6e-13 50.5 0.1 2.0 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EPX72773.1 - 0.038 14.2 0.0 0.23 11.7 0.0 2.3 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF155 PF02582.9 EPX72774.1 - 9.6e-56 188.4 0.0 1.8e-55 187.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Gag_p12 PF01141.13 EPX72774.1 - 4.8 7.3 9.4 4.5 7.4 0.5 2.5 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 WD40 PF00400.27 EPX72775.1 - 4.5e-58 191.1 12.9 6.8e-10 38.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EPX72775.1 - 2.6e-07 30.5 0.3 0.12 12.0 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPX72775.1 - 0.025 12.7 0.2 5.4 5.0 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Nuc_sug_transp PF04142.10 EPX72776.1 - 3e-08 33.0 0.2 3e-08 33.0 0.1 1.9 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 EPX72776.1 - 7.6e-05 22.7 4.9 7.6e-05 22.7 3.4 3.1 2 1 0 2 2 2 1 EamA-like transporter family DUF914 PF06027.7 EPX72776.1 - 0.0001 21.3 4.4 0.0001 21.3 3.1 2.2 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EPX72776.1 - 0.00011 22.4 3.3 0.00011 22.4 2.3 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 EPX72776.1 - 0.0014 18.4 0.7 0.0044 16.8 0.3 2.0 2 0 0 2 2 2 1 Uncharacterised protein family UPF0546 TPT PF03151.11 EPX72776.1 - 1.5 8.4 22.0 0.32 10.6 6.2 2.5 3 0 0 3 3 3 0 Triose-phosphate Transporter family ATPase_gene1 PF09527.5 EPX72776.1 - 1.6 8.5 11.1 1.2 8.9 1.3 3.6 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) MerC PF03203.9 EPX72776.1 - 2.1 8.7 15.2 0.11 12.8 3.4 3.2 2 1 1 3 3 3 0 MerC mercury resistance protein NTP_transf_2 PF01909.18 EPX72777.1 - 4.6e-14 52.4 0.0 1.5e-13 50.8 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EPX72777.1 - 6.3e-13 48.4 0.0 2.1e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase CHD5 PF04420.9 EPX72778.1 - 1.7e-43 148.0 5.7 2.1e-43 147.7 3.9 1.0 1 0 0 1 1 1 1 CHD5-like protein DUF1240 PF06836.7 EPX72778.1 - 0.31 11.2 4.6 1.5 9.0 0.2 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1240) AAA_23 PF13476.1 EPX72778.1 - 0.33 11.2 5.2 0.44 10.8 3.6 1.1 1 0 0 1 1 1 0 AAA domain ChaB PF06150.7 EPX72778.1 - 0.34 10.7 5.0 0.52 10.1 0.7 2.6 2 1 0 2 2 2 0 ChaB Peptidase_M41 PF01434.13 EPX72779.1 - 2.7e-73 245.9 0.2 4e-73 245.4 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EPX72779.1 - 3.6e-42 143.6 0.0 7.4e-42 142.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EPX72779.1 - 6.1e-10 39.2 0.1 1.9e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 EPX72779.1 - 0.00049 20.9 0.0 0.0034 18.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPX72779.1 - 0.0023 17.6 0.0 0.007 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EPX72779.1 - 0.0032 17.1 0.2 0.008 15.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EPX72779.1 - 0.0036 17.4 0.0 0.11 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EPX72779.1 - 0.0047 15.7 0.0 0.0074 15.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 EPX72779.1 - 0.0062 15.6 0.1 0.056 12.5 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 EPX72779.1 - 0.0088 16.0 0.2 0.056 13.4 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EPX72779.1 - 0.0089 15.0 0.0 0.032 13.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EPX72779.1 - 0.02 14.7 0.0 0.072 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EPX72779.1 - 0.034 13.5 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EPX72779.1 - 0.054 12.9 0.4 0.17 11.2 0.2 1.8 1 1 1 2 2 2 0 AAA domain Scs3p PF10261.4 EPX72780.1 - 2.9e-51 173.8 25.3 6.2e-40 136.7 6.6 2.2 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM Pkinase PF00069.20 EPX72781.1 - 5.1e-59 199.5 0.0 7.1e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72781.1 - 8.3e-37 126.6 0.0 1.1e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX72781.1 - 1.2e-07 31.0 0.0 2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPX72781.1 - 0.087 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EPX72781.1 - 0.098 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EPX72781.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DEAD PF00270.24 EPX72782.1 - 4.5e-42 143.4 0.1 1.8e-41 141.4 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX72782.1 - 1.8e-26 91.7 0.1 3.7e-26 90.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX72782.1 - 0.00042 20.1 0.0 0.0018 18.1 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HCO3_cotransp PF00955.16 EPX72783.1 - 4.8e-59 200.3 14.7 3.1e-35 121.8 2.3 2.0 1 1 1 2 2 2 2 HCO3- transporter family NPR3 PF03666.8 EPX72784.1 - 7.1e-121 403.8 6.7 1.6e-120 402.7 4.7 1.5 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Ku PF02735.11 EPX72785.1 - 2.4e-39 134.8 0.2 5.4e-39 133.6 0.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EPX72785.1 - 1.5e-36 125.9 0.8 2.5e-36 125.2 0.6 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EPX72785.1 - 4.5e-06 26.5 0.2 1.7e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Ku C terminal domain like TPR_11 PF13414.1 EPX72786.1 - 2e-41 139.4 19.7 1.1e-14 53.7 1.3 5.6 3 1 2 6 6 6 4 TPR repeat TPR_1 PF00515.23 EPX72786.1 - 1e-28 97.7 24.6 4.2e-06 26.1 0.0 7.2 8 0 0 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.26 EPX72786.1 - 5.6e-28 96.4 0.8 5.6e-28 96.4 0.6 2.8 4 0 0 4 4 4 1 DnaJ domain TPR_2 PF07719.12 EPX72786.1 - 2.6e-27 92.4 22.4 1.6e-07 30.7 0.0 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 EPX72786.1 - 3.6e-17 62.5 20.0 3.6e-06 27.4 0.1 6.0 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EPX72786.1 - 3.2e-14 52.1 11.4 0.0031 17.9 0.0 7.7 4 3 4 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPX72786.1 - 2.4e-13 49.8 17.9 0.00057 19.7 0.2 5.6 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPX72786.1 - 8.8e-12 45.1 20.9 0.00079 19.7 0.1 5.9 3 2 2 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EPX72786.1 - 8.7e-10 38.6 12.1 0.0018 18.3 0.5 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EPX72786.1 - 9.7e-09 34.3 21.8 0.0015 18.1 0.0 7.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPX72786.1 - 1.1e-08 34.6 9.9 0.016 15.3 0.2 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPX72786.1 - 8.5e-08 31.9 2.0 0.016 15.0 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EPX72786.1 - 3.5e-05 23.0 10.5 0.013 14.5 0.5 4.5 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPX72786.1 - 0.00015 21.2 11.4 2.1 8.3 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPX72786.1 - 0.0012 19.1 14.0 0.14 12.6 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat MIT PF04212.13 EPX72786.1 - 0.0071 16.1 10.1 1.4 8.8 0.2 4.8 3 1 2 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 EPX72786.1 - 0.033 13.9 6.4 0.26 11.1 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EPX72786.1 - 0.14 11.4 1.9 16 4.8 0.0 3.8 4 0 0 4 4 4 0 SHNi-TPR Septin PF00735.13 EPX72787.1 - 4.5e-106 353.9 0.0 6e-106 353.5 0.0 1.1 1 0 0 1 1 1 1 Septin DUF770 PF05591.7 EPX72787.1 - 0.029 13.9 0.4 0.38 10.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF770) AIG1 PF04548.11 EPX72787.1 - 0.05 12.6 0.0 0.12 11.5 0.0 1.7 1 1 0 1 1 1 0 AIG1 family SPT2 PF08243.6 EPX72787.1 - 0.13 12.6 0.1 0.13 12.6 0.1 2.5 3 0 0 3 3 3 0 SPT2 chromatin protein ADH_zinc_N PF00107.21 EPX72788.1 - 1.2e-14 53.9 0.1 3.5e-14 52.4 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPX72788.1 - 2.6e-14 54.1 0.0 1.1e-13 52.2 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPX72788.1 - 3.6e-12 45.9 0.1 1e-11 44.5 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EPX72788.1 - 4.5e-06 26.3 0.3 0.00023 20.7 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 EPX72788.1 - 0.00076 19.5 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPX72788.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Met_10 PF02475.11 EPX72788.1 - 0.0085 15.7 0.7 0.87 9.1 0.0 2.8 3 0 0 3 3 3 1 Met-10+ like-protein ELFV_dehydrog PF00208.16 EPX72788.1 - 0.011 15.3 0.4 0.019 14.5 0.3 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Eno-Rase_NADH_b PF12242.3 EPX72788.1 - 0.027 14.2 0.7 0.027 14.2 0.5 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 EPX72789.1 - 6.4e-15 54.8 0.2 2.1e-14 53.1 0.0 2.1 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPX72789.1 - 1.3e-13 51.9 0.0 4.3e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPX72789.1 - 5.3e-11 42.2 0.0 2e-10 40.3 0.0 1.9 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EPX72789.1 - 0.00012 21.6 0.1 0.00022 20.8 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 EPX72789.1 - 0.0013 18.7 0.1 0.0032 17.5 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EPX72789.1 - 0.0071 16.1 1.7 0.029 14.1 0.2 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EPX72789.1 - 0.0087 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.16 EPX72789.1 - 0.016 14.7 0.4 0.025 14.1 0.3 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Erythrovirus_X PF06795.6 EPX72789.1 - 0.021 14.8 0.2 0.065 13.2 0.0 1.8 2 0 0 2 2 2 0 Erythrovirus X protein DapB_N PF01113.15 EPX72789.1 - 0.1 12.4 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF3943 PF13084.1 EPX72789.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) Met_10 PF02475.11 EPX72789.1 - 0.18 11.3 0.5 1 8.8 0.1 2.2 2 0 0 2 2 2 0 Met-10+ like-protein UDG PF03167.14 EPX72790.1 - 2.4e-18 66.0 0.0 3.7e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Myb_DNA-bind_5 PF13873.1 EPX72790.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain PPR_2 PF13041.1 EPX72791.1 - 0.0086 16.0 0.1 15 5.6 0.0 4.2 2 1 1 3 3 3 2 PPR repeat family MRP-S25 PF13741.1 EPX72792.1 - 1.4e-64 217.7 11.7 2.1e-62 210.6 8.1 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 CCDC144C PF14915.1 EPX72792.1 - 0.058 12.3 0.9 0.092 11.6 0.7 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region MRP-S23 PF10484.4 EPX72792.1 - 4.3 7.2 6.3 2.5 8.0 1.4 2.3 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 WD40 PF00400.27 EPX72793.1 - 7.5e-32 108.0 5.5 2.5e-08 33.4 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EPX72793.1 - 0.12 12.0 0.0 0.46 10.1 0.0 2.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A A_deamin PF02137.13 EPX72794.1 - 2.2e-65 221.2 0.2 3e-65 220.8 0.1 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain CorC_HlyC PF03471.12 EPX72794.1 - 0.16 11.7 0.0 0.76 9.6 0.0 1.9 1 1 0 1 1 1 0 Transporter associated domain Whi5 PF08528.6 EPX72795.1 - 6.9e-07 28.7 0.6 1.8e-06 27.3 0.3 1.9 2 0 0 2 2 2 1 Whi5 like Drc1-Sld2 PF11719.3 EPX72795.1 - 0.00051 19.2 0.6 0.00051 19.2 0.4 2.0 1 1 0 2 2 2 1 DNA replication and checkpoint protein Stm1_N PF09598.5 EPX72796.1 - 5.1e-15 55.9 10.3 5.1e-15 55.9 7.1 4.1 3 1 0 3 3 3 1 Stm1 UFD1 PF03152.9 EPX72797.1 - 4.2e-66 221.4 0.0 5.9e-66 220.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 RRM_1 PF00076.17 EPX72798.1 - 5.2e-09 35.6 0.0 1.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX72798.1 - 1.7e-08 34.2 0.0 3.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX72798.1 - 3.6e-05 23.5 0.0 6.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3886 PF13025.1 EPX72798.1 - 0.072 13.0 7.4 0.12 12.3 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) DUF773 PF05600.7 EPX72798.1 - 0.17 10.6 0.5 0.24 10.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF773) MFS_1 PF07690.11 EPX72799.1 - 1.9e-41 141.9 50.1 1.1e-40 139.4 33.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX72799.1 - 1.6e-16 59.9 1.6 1.6e-16 59.9 1.1 2.6 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EPX72799.1 - 2.1e-11 42.7 14.1 4.1e-11 41.8 9.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pet191_N PF10203.4 EPX72800.1 - 4.8e-23 80.9 5.9 5.5e-23 80.7 4.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EPX72800.1 - 0.17 11.7 4.7 2 8.2 0.5 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EPX72800.1 - 0.78 9.7 5.0 0.16 11.8 0.9 1.9 2 0 0 2 2 2 0 CHCH domain Tubulin PF00091.20 EPX72801.1 - 3.4e-70 236.2 0.0 4.6e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPX72801.1 - 2.3e-49 166.5 0.0 4e-49 165.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EPX72801.1 - 0.019 14.4 0.0 0.056 12.9 0.0 1.8 1 0 0 1 1 1 0 Tubulin domain DUF4474 PF14751.1 EPX72801.1 - 0.13 11.4 0.0 0.63 9.1 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4474) HSF_DNA-bind PF00447.12 EPX72802.1 - 1.5e-34 118.2 0.3 3.4e-34 117.1 0.2 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Myb_DNA-binding PF00249.26 EPX72803.1 - 4.1e-09 36.3 0.5 1.1e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain ArfGap PF01412.13 EPX72804.1 - 2.9e-33 114.1 0.2 2.9e-33 114.1 0.2 2.0 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf GCIP PF13324.1 EPX72805.1 - 1e-05 24.9 0.1 1.7e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting NTS PF15447.1 EPX72805.1 - 0.05 14.0 0.1 4.3 7.8 0.0 2.6 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 IncA PF04156.9 EPX72805.1 - 0.72 9.4 4.8 1.3 8.6 3.3 1.5 1 1 0 1 1 1 0 IncA protein DUF2890 PF11081.3 EPX72805.1 - 0.78 9.7 8.2 1.1 9.2 5.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) RP-C_C PF11800.3 EPX72805.1 - 0.78 9.3 3.4 8.3 6.0 0.0 2.6 1 1 2 3 3 3 0 Replication protein C C-terminal region PI3_PI4_kinase PF00454.22 EPX72806.1 - 4.6e-28 98.2 0.1 8e-28 97.4 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EPX72806.1 - 1.9e-17 62.7 0.6 4.1e-17 61.6 0.4 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 EPX72806.1 - 1.2e-06 27.8 0.5 3.2e-06 26.4 0.3 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.1 EPX72806.1 - 0.023 13.6 0.1 0.068 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Pkinase PF00069.20 EPX72807.1 - 3.3e-65 219.8 0.0 5.7e-65 219.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72807.1 - 3.7e-26 91.7 0.0 5.3e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EPX72807.1 - 1.7e-10 41.2 2.1 1.7e-10 41.2 1.4 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPX72807.1 - 3.7e-08 32.6 0.0 5.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPX72807.1 - 0.0021 17.8 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EPX72807.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L24e PF01246.15 EPX72808.1 - 4.7e-35 119.2 2.5 4.7e-35 119.2 1.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2175 PF09943.4 EPX72808.1 - 0.038 14.0 0.6 0.1 12.6 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF2218 PF09981.4 EPX72808.1 - 0.051 13.7 0.2 0.092 12.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) HGTP_anticodon2 PF12745.2 EPX72808.1 - 0.079 12.0 1.6 0.11 11.5 1.1 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs PHD PF00628.24 EPX72809.1 - 1.2e-09 37.6 9.1 2.3e-09 36.7 6.3 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EPX72809.1 - 4.4e-06 27.0 0.2 4.5e-05 23.8 0.0 2.8 2 1 0 2 2 2 1 SET domain PHD_2 PF13831.1 EPX72809.1 - 0.0015 17.7 4.9 0.0033 16.7 3.4 1.5 1 0 0 1 1 1 1 PHD-finger COX15-CtaA PF02628.10 EPX72810.1 - 5.3e-94 314.4 11.1 6.4e-94 314.2 7.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Fer2 PF00111.22 EPX72810.1 - 1.3e-12 47.2 0.3 2.2e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Peptidase_S8 PF00082.17 EPX72811.1 - 1.6e-55 188.2 0.0 2e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EPX72811.1 - 6.3e-26 89.9 0.0 1.6e-25 88.7 0.0 1.7 2 0 0 2 2 2 1 Proprotein convertase P-domain UAF_Rrn10 PF05234.6 EPX72812.1 - 1.2e-18 67.2 0.1 1.7e-18 66.7 0.0 1.5 1 1 0 1 1 1 1 UAF complex subunit Rrn10 SSPI PF14098.1 EPX72812.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Small, acid-soluble spore protein I Glyco_transf_34 PF05637.7 EPX72813.1 - 9.9e-79 264.1 0.0 1.3e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 EPX72813.1 - 0.007 16.1 0.0 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DevR PF01905.11 EPX72813.1 - 0.17 10.7 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 LRR_6 PF13516.1 EPX72814.1 - 5e-14 50.7 2.7 0.22 11.7 0.1 6.9 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.2 EPX72814.1 - 4.5e-07 29.3 10.4 0.019 14.5 1.1 4.8 4 2 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPX72814.1 - 2.6e-06 26.6 5.7 13 6.2 0.0 6.6 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EPX72814.1 - 0.0016 18.2 3.9 77 4.1 0.0 5.9 5 0 0 5 5 5 0 Leucine rich repeat LRR_8 PF13855.1 EPX72814.1 - 0.021 14.5 9.1 0.59 9.9 0.4 4.5 4 2 2 6 6 6 0 Leucine rich repeat Nucleoplasmin PF03066.10 EPX72814.1 - 2.4 7.6 16.4 6.6 6.2 11.3 1.7 1 0 0 1 1 1 0 Nucleoplasmin Rer1 PF03248.8 EPX72816.1 - 6.9e-74 247.2 5.0 7.8e-74 247.0 3.5 1.0 1 0 0 1 1 1 1 Rer1 family EI24 PF07264.6 EPX72816.1 - 7.6e-05 22.2 3.7 9.3e-05 21.9 2.6 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3149 PF11346.3 EPX72816.1 - 0.18 11.3 3.1 0.55 9.8 2.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF4400 PF14348.1 EPX72816.1 - 0.55 9.5 7.3 0.23 10.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) RRM_1 PF00076.17 EPX72817.1 - 1.1e-16 60.2 0.0 1.9e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX72817.1 - 1.2e-11 44.4 0.1 2.9e-11 43.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ldh_1_C PF02866.13 EPX72817.1 - 0.0055 16.4 0.1 0.008 15.9 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glycos_trans_3N PF02885.12 EPX72817.1 - 0.082 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain RRM_5 PF13893.1 EPX72817.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DJ-1_PfpI PF01965.19 EPX72818.1 - 2.7e-29 101.5 0.0 3.5e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EPX72818.1 - 2.1e-14 53.1 0.0 2.9e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase CofC PF01983.11 EPX72818.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like TPT PF03151.11 EPX72819.1 - 6.7e-36 123.2 10.4 6.7e-36 123.2 7.2 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EPX72819.1 - 6.8e-11 41.6 24.1 1.3e-10 40.7 16.5 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPX72819.1 - 3.3e-08 33.6 31.6 9.9e-05 22.3 5.2 2.8 2 1 0 2 2 2 2 EamA-like transporter family DUF2530 PF10745.4 EPX72819.1 - 0.13 12.2 3.1 0.14 12.1 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) SNAP PF14938.1 EPX72819.1 - 0.21 10.6 0.0 0.3 10.2 0.0 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP EmrE PF13536.1 EPX72819.1 - 1.5 9.0 29.7 0.08 13.1 4.5 3.5 1 1 0 3 3 3 0 Multidrug resistance efflux transporter Ribosomal_L31e PF01198.14 EPX72820.1 - 3.8e-36 122.6 1.8 4.9e-36 122.2 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Methyltransf_31 PF13847.1 EPX72821.1 - 2.8e-13 49.7 0.0 4.6e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX72821.1 - 6.3e-12 45.8 0.0 2.4e-11 43.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EPX72821.1 - 6.6e-12 45.1 0.0 9.1e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EPX72821.1 - 4.3e-10 40.1 0.0 2.2e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPX72821.1 - 1.2e-09 38.1 0.0 3e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX72821.1 - 2.3e-08 33.9 0.0 2e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPX72821.1 - 2e-06 27.3 0.1 3.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EPX72821.1 - 2.6e-06 26.3 0.2 3.8e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EPX72821.1 - 2.8e-06 27.6 0.1 3e-05 24.2 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX72821.1 - 6.4e-06 26.5 0.0 1.8e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 EPX72821.1 - 2e-05 23.7 0.0 2.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase FtsJ PF01728.14 EPX72821.1 - 7.5e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 EPX72821.1 - 0.00014 21.0 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EPX72821.1 - 0.0009 18.7 0.1 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.1 EPX72821.1 - 0.0042 17.9 0.0 0.013 16.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EPX72821.1 - 0.007 16.0 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EPX72821.1 - 0.0097 15.0 1.7 0.017 14.2 0.1 2.2 2 2 1 3 3 3 1 Tellurite resistance protein TehB Methyltransf_2 PF00891.13 EPX72821.1 - 0.028 13.6 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Ubie_methyltran PF01209.13 EPX72821.1 - 0.029 13.4 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 EPX72821.1 - 0.03 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PCMT PF01135.14 EPX72821.1 - 0.089 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Nucleoporin_C PF03177.9 EPX72822.1 - 3e-103 346.3 12.2 3.8e-103 346.0 8.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EPX72822.1 - 2.9e-79 266.8 5.9 5.3e-79 265.9 4.1 1.4 1 0 0 1 1 1 1 Nup133 N terminal like WD40 PF00400.27 EPX72823.1 - 1.5e-31 107.1 13.9 1.9e-07 30.7 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 EPX72823.1 - 7.4e-27 93.1 0.2 1.9e-26 91.8 0.1 1.7 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EPX72823.1 - 5.9e-06 24.7 1.8 0.0073 14.4 0.0 3.4 2 1 0 3 3 3 2 Nucleoporin Nup120/160 G-patch PF01585.18 EPX72824.1 - 2.3e-13 49.6 0.5 5.7e-13 48.4 0.4 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EPX72824.1 - 5.1e-06 26.2 0.2 5.1e-06 26.2 0.1 4.8 3 1 0 3 3 3 1 DExH-box splicing factor binding site MIP-T3 PF10243.4 EPX72824.1 - 0.022 13.2 55.6 0.031 12.7 38.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF936 PF06075.7 EPX72824.1 - 0.037 12.9 30.5 0.044 12.7 21.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) CDC27 PF09507.5 EPX72824.1 - 0.67 9.1 48.8 0.96 8.6 33.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF572 PF04502.8 EPX72824.1 - 1.3 8.1 40.7 2 7.5 28.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) TIMELESS_C PF05029.8 EPX72824.1 - 2.6 6.8 40.3 4.5 6.0 27.9 1.3 1 0 0 1 1 1 0 Timeless protein C terminal region PLRV_ORF5 PF01690.12 EPX72824.1 - 6.4 5.8 26.8 8.6 5.3 18.6 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Hid1 PF12722.2 EPX72824.1 - 8.8 3.8 30.6 11 3.5 21.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase PF00069.20 EPX72825.1 - 4.1e-69 232.6 0.0 5.9e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72825.1 - 2.6e-41 141.4 0.0 3.7e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX72825.1 - 8.3e-08 31.5 0.0 1.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPX72825.1 - 0.00059 18.9 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TACC PF05010.9 EPX72826.1 - 1.3e-22 80.6 34.2 1.3e-21 77.3 23.7 2.2 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) Kinetocho_Slk19 PF12709.2 EPX72826.1 - 2e-15 56.5 28.1 1.1e-11 44.6 3.2 4.5 4 0 0 4 4 4 3 Central kinetochore-associated Pep_deformylase PF01327.16 EPX72826.1 - 0.019 14.3 0.2 0.51 9.7 0.4 2.5 2 1 0 2 2 2 0 Polypeptide deformylase DUF2746 PF10874.3 EPX72826.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2746) DUF4140 PF13600.1 EPX72826.1 - 0.6 10.5 0.0 0.6 10.5 0.0 4.4 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Pup PF05639.6 EPX72826.1 - 0.71 10.4 6.0 0.24 11.9 0.5 2.8 2 0 0 2 2 2 0 Pup-like protein Aldo_ket_red PF00248.16 EPX72827.1 - 2.6e-64 216.8 0.0 2.9e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF836 PF05768.9 EPX72827.1 - 0.034 14.4 0.0 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) RabGAP-TBC PF00566.13 EPX72828.1 - 6.7e-35 120.5 18.3 3.5e-33 114.8 1.1 3.4 3 1 0 3 3 3 2 Rab-GTPase-TBC domain RhoGAP PF00620.22 EPX72829.1 - 4.6e-08 32.8 0.7 1.1e-07 31.6 0.5 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EPX72829.1 - 0.084 13.0 1.5 0.47 10.6 0.5 2.7 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Mei4 PF13971.1 EPX72830.1 - 7.9e-32 110.6 9.3 1e-31 110.2 6.5 1.0 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 Trans_reg_C PF00486.23 EPX72830.1 - 0.047 13.6 0.3 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal VitD-bind_III PF09164.5 EPX72830.1 - 0.25 10.9 2.1 0.41 10.2 0.1 2.2 2 0 0 2 2 2 0 Vitamin D binding protein, domain III DUF1524 PF07510.6 EPX72831.1 - 0.066 13.0 0.5 0.12 12.2 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1524) LNS2 PF08235.8 EPX72832.1 - 1.1e-73 245.9 0.0 1.8e-73 245.2 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EPX72832.1 - 1.5e-42 143.7 0.0 3.1e-42 142.7 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 EPX72832.1 - 5.1e-05 23.1 3.4 0.00014 21.7 2.3 1.7 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator Acid_phosphat_B PF03767.9 EPX72832.1 - 0.00092 18.6 0.0 0.0053 16.1 0.0 2.2 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_6 PF13344.1 EPX72832.1 - 0.092 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Imm15 PF15590.1 EPX72832.1 - 0.28 10.2 2.0 0.67 9.0 0.7 2.1 2 0 0 2 2 2 0 Immunity protein 15 PCI PF01399.22 EPX72833.1 - 6e-05 23.3 0.4 0.00043 20.5 0.0 2.3 2 1 1 3 3 3 1 PCI domain Acp26Ab PF05777.7 EPX72833.1 - 0.013 15.9 1.2 1.7 9.0 0.1 2.4 2 0 0 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) INTS5_N PF14837.1 EPX72833.1 - 0.065 12.6 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus Amidohydro_1 PF01979.15 EPX72834.1 - 2.2e-55 188.6 0.1 3.2e-55 188.1 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EPX72834.1 - 4.7e-53 178.4 4.1 9e-53 177.5 2.8 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EPX72834.1 - 8.5e-40 134.6 0.0 1.8e-39 133.6 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 EPX72834.1 - 7.7e-37 125.2 0.0 1.9e-36 124.0 0.0 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EPX72834.1 - 1.7e-07 30.9 0.9 4.2e-07 29.6 0.6 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EPX72834.1 - 0.0044 16.3 0.0 0.0087 15.3 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family DUF4448 PF14610.1 EPX72835.1 - 0.14 11.6 0.3 0.33 10.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) AcetylCoA_hydro PF02550.10 EPX72836.1 - 1.1e-48 165.6 0.0 2e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EPX72836.1 - 1.5e-41 141.6 0.0 2.7e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 EPX72836.1 - 0.0016 17.6 0.1 0.26 10.4 0.0 2.4 2 0 0 2 2 2 2 Coenzyme A transferase Pyridox_oxidase PF01243.15 EPX72837.1 - 6.6e-11 42.0 0.0 1.4e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Rad1 PF02144.11 EPX72838.1 - 7.1e-64 215.2 0.5 8.5e-64 214.9 0.3 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 CTNNBL PF08216.6 EPX72839.1 - 5.7e-34 115.9 0.3 1.5e-33 114.5 0.2 1.8 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear UNC45-central PF11701.3 EPX72839.1 - 0.34 10.5 3.4 0.83 9.2 0.4 2.8 2 2 2 4 4 4 0 Myosin-binding striated muscle assembly central Bromodomain PF00439.20 EPX72840.1 - 1.3e-26 92.2 0.6 3.2e-26 91.0 0.4 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EPX72840.1 - 1.6e-10 40.9 0.3 3.9e-10 39.7 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPX72840.1 - 2.2e-09 37.1 0.4 4.8e-09 36.1 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EPX72840.1 - 0.0014 18.5 2.8 0.012 15.6 0.1 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain OTU PF02338.14 EPX72842.1 - 1.1e-24 87.3 0.3 1.1e-24 87.3 0.2 2.4 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EPX72842.1 - 6.7e-12 45.2 2.3 1.1e-09 38.0 0.0 3.1 2 1 1 3 3 3 2 Peptidase C65 Otubain OAR PF03826.12 EPX72842.1 - 0.1 12.1 0.1 0.3 10.6 0.1 1.9 1 0 0 1 1 1 0 OAR domain Hid1 PF12722.2 EPX72842.1 - 5.7 4.4 18.7 7.4 4.1 13.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein G-patch PF01585.18 EPX72843.1 - 0.023 14.4 0.1 0.076 12.8 0.1 2.0 1 0 0 1 1 1 0 G-patch domain U79_P34 PF03064.11 EPX72843.1 - 0.07 12.6 24.5 0.086 12.3 17.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SRP-alpha_N PF04086.8 EPX72843.1 - 0.31 10.4 30.5 0.39 10.0 21.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.9 EPX72843.1 - 0.49 8.3 19.5 0.55 8.2 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein MIP-T3 PF10243.4 EPX72843.1 - 0.93 7.8 35.7 1.1 7.6 24.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hex_IIIa PF02455.11 EPX72843.1 - 2.7 6.5 15.9 3.1 6.3 11.0 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Mem_trans PF03547.13 EPX72843.1 - 7.4 4.7 10.0 9 4.4 6.9 1.1 1 0 0 1 1 1 0 Membrane transport protein Macoilin PF09726.4 EPX72843.1 - 8.8 4.4 24.1 9.5 4.3 16.7 1.0 1 0 0 1 1 1 0 Transmembrane protein PIG-U PF06728.8 EPX72844.1 - 4.6e-86 289.0 39.9 5.8e-86 288.7 27.6 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Ribosomal_S11 PF00411.14 EPX72845.1 - 6.9e-08 32.6 0.0 8.4e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 BcrAD_BadFG PF01869.15 EPX72845.1 - 0.014 14.6 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Clr2 PF10383.4 EPX72846.1 - 7.8e-13 48.6 0.0 1.7e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 MFS_1 PF07690.11 EPX72847.1 - 7.7e-27 93.9 26.7 7.7e-27 93.9 18.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily ATP-synt_C PF00137.16 EPX72848.1 - 1.8e-31 107.8 32.0 1e-18 66.9 8.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C WD40 PF00400.27 EPX72849.1 - 0.0005 19.8 1.3 1.5 8.8 0.0 4.2 4 1 0 4 4 4 2 WD domain, G-beta repeat RNA_pol_N PF01194.12 EPX72850.1 - 1.4e-31 108.2 0.5 1.7e-31 108.0 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit YhfH PF14149.1 EPX72850.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 2 0 0 2 2 2 0 YhfH-like protein Ras PF00071.17 EPX72851.1 - 6.4e-50 168.6 0.1 8.5e-50 168.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX72851.1 - 2.7e-17 63.3 0.0 4e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX72851.1 - 7.2e-13 48.1 0.0 9.5e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPX72851.1 - 9.6e-07 28.1 0.0 1.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPX72851.1 - 5.9e-05 22.5 0.0 0.00034 20.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPX72851.1 - 0.00021 21.2 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPX72851.1 - 0.00076 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EPX72851.1 - 0.0044 17.1 0.0 0.0086 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPX72851.1 - 0.0089 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPX72851.1 - 0.018 14.2 0.0 0.042 13.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPX72851.1 - 0.042 13.8 0.1 0.074 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EPX72851.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 EPX72851.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EPX72851.1 - 0.064 13.5 0.0 0.1 12.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EPX72851.1 - 0.072 12.6 0.0 0.23 11.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EPX72851.1 - 0.09 12.4 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sel1 PF08238.7 EPX72853.1 - 7.2e-19 67.7 24.4 7e-06 26.5 0.3 9.0 9 0 0 9 9 9 7 Sel1 repeat DUF187 PF02638.10 EPX72853.1 - 0.13 11.0 0.9 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase like GH101 TPR_11 PF13414.1 EPX72853.1 - 0.37 10.4 4.2 1.3 8.7 0.1 3.6 3 1 1 4 4 4 0 TPR repeat Noc2 PF03715.8 EPX72854.1 - 1.1e-63 214.9 12.6 1.6e-63 214.3 8.7 1.3 1 0 0 1 1 1 1 Noc2p family BP28CT PF08146.7 EPX72854.1 - 0.0013 18.4 0.4 0.0041 16.8 0.3 1.9 1 0 0 1 1 1 1 BP28CT (NUC211) domain Peptidase_C80 PF11713.3 EPX72854.1 - 0.073 12.8 1.1 0.1 12.3 0.1 1.8 2 0 0 2 2 2 0 Peptidase C80 family PCI PF01399.22 EPX72855.1 - 2.6e-12 46.9 0.0 7e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 PCI domain VPS28 PF03997.7 EPX72856.1 - 1.8e-60 203.7 0.4 2.5e-60 203.3 0.3 1.2 1 0 0 1 1 1 1 VPS28 protein Not3 PF04065.10 EPX72857.1 - 4.1e-91 304.4 24.7 5.9e-91 303.8 17.1 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EPX72857.1 - 1.8e-43 147.6 5.8 6.8e-43 145.7 4.0 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 EPX72857.1 - 0.0042 16.5 0.8 0.02 14.4 0.7 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) DUF948 PF06103.6 EPX72857.1 - 0.68 9.8 3.9 0.73 9.7 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.16 EPX72857.1 - 6.9 6.7 9.5 0.33 10.9 0.6 3.0 2 1 1 3 3 3 0 bZIP transcription factor GTP_EFTU PF00009.22 EPX72858.1 - 5.3e-47 159.6 0.0 7.7e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EPX72858.1 - 1.3e-39 134.4 0.5 2.9e-39 133.2 0.3 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EPX72858.1 - 3.7e-20 71.5 0.0 1.1e-19 70.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPX72858.1 - 1.7e-10 40.8 0.4 3.4e-10 39.9 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EPX72858.1 - 2.5e-07 30.4 0.0 5.9e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EPX72858.1 - 0.0001 22.2 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EPX72858.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EPX72858.1 - 0.0014 17.8 0.0 0.0028 16.9 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EPX72858.1 - 0.066 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Pro_isomerase PF00160.16 EPX72859.1 - 2e-44 151.5 0.5 3e-44 150.9 0.3 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.23 EPX72859.1 - 1.2e-06 27.8 11.4 0.0018 17.8 0.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EPX72859.1 - 1.6e-06 27.6 0.5 1.6e-06 27.6 0.4 2.7 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EPX72859.1 - 5.4e-05 22.8 13.3 0.051 13.4 0.3 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPX72859.1 - 0.00044 20.1 4.7 0.044 13.7 1.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPX72859.1 - 0.017 14.8 0.3 0.017 14.8 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPX72859.1 - 0.034 14.7 2.1 2.7 8.8 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPX72859.1 - 0.041 14.3 3.6 45 4.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPX72859.1 - 0.091 12.5 5.9 24 5.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPX72859.1 - 0.26 12.0 2.8 9.3 7.0 0.3 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPX72859.1 - 1.4 9.3 3.9 45 4.5 0.1 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4398 PF14346.1 EPX72859.1 - 6.2 6.9 7.3 43 4.2 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Elf1 PF05129.8 EPX72860.1 - 2.6e-28 97.5 1.6 3.2e-28 97.2 1.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like SCA7 PF08313.7 EPX72860.1 - 0.4 10.3 3.3 0.54 9.8 2.3 1.4 1 1 0 1 1 1 0 SCA7, zinc-binding domain UPRTase PF14681.1 EPX72861.1 - 2.5e-77 258.7 0.0 2.8e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EPX72861.1 - 6e-05 22.7 0.0 9.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain B12D PF06522.6 EPX72862.1 - 0.0013 18.3 0.0 0.0016 18.0 0.0 1.3 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit TIP49 PF06068.8 EPX72863.1 - 2.2e-189 629.2 0.4 2.6e-189 629.0 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EPX72863.1 - 5.9e-09 36.2 0.3 5e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPX72863.1 - 1.4e-07 30.7 0.7 0.00045 19.3 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EPX72863.1 - 0.00046 20.3 0.4 0.31 11.1 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EPX72863.1 - 0.00063 19.7 0.0 0.97 9.3 0.0 2.3 1 1 1 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 EPX72863.1 - 0.016 15.1 0.1 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EPX72863.1 - 0.017 14.1 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EPX72863.1 - 0.017 14.8 0.1 0.053 13.2 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EPX72863.1 - 0.041 14.7 0.1 7.8 7.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EPX72863.1 - 0.042 12.9 0.1 5.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPX72863.1 - 0.067 12.9 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NUC173 PF08161.7 EPX72864.1 - 3.4e-65 219.1 0.3 2.4e-61 206.5 0.0 3.3 3 0 0 3 3 3 2 NUC173 domain HEAT_EZ PF13513.1 EPX72864.1 - 0.0039 17.6 0.3 1.9 9.0 0.0 4.3 3 0 0 3 3 3 1 HEAT-like repeat Ipi1_N PF12333.3 EPX72864.1 - 0.011 15.6 10.4 2.8 7.9 0.0 5.3 5 2 1 6 6 6 0 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 EPX72864.1 - 0.011 15.7 2.2 0.11 12.5 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat RIX1 PF08167.7 EPX72864.1 - 0.013 15.1 8.4 0.016 14.8 0.1 4.0 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Ribosomal_L3 PF00297.17 EPX72865.1 - 1.2e-120 401.8 5.9 1.4e-120 401.5 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 M-factor PF03855.8 EPX72866.1 - 1.4e-05 24.9 10.8 3.1e-05 23.8 7.5 1.5 1 1 0 1 1 1 1 M-factor BCDHK_Adom3 PF10436.4 EPX72867.1 - 4.9e-50 169.2 0.0 6.6e-50 168.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EPX72867.1 - 2.8e-15 55.9 0.0 4.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EPX72867.1 - 1.2e-05 24.9 0.0 4.9e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med11 PF10280.4 EPX72868.1 - 2.8e-10 40.2 0.5 3.6e-10 39.9 0.3 1.1 1 0 0 1 1 1 1 Mediator complex protein KGK PF08872.5 EPX72868.1 - 0.023 14.8 0.3 0.031 14.4 0.2 1.2 1 0 0 1 1 1 0 KGK domain DUF2775 PF10950.3 EPX72868.1 - 0.083 13.1 1.6 0.13 12.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2775) TPP1 PF10341.4 EPX72868.1 - 0.12 12.3 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD Ala_racemase_N PF01168.15 EPX72869.1 - 1.1e-43 149.3 0.0 1.3e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HAD_2 PF13419.1 EPX72870.1 - 1.3e-24 87.3 0.0 1.6e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase BCS1_N PF08740.6 EPX72871.1 - 4.2e-49 166.7 0.0 5.5e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EPX72871.1 - 2.2e-19 69.9 0.0 3.9e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPX72871.1 - 4.8e-05 24.1 0.0 0.0001 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPX72871.1 - 0.003 16.9 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EPX72871.1 - 0.0031 17.5 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPX72871.1 - 0.0042 17.3 0.0 0.0078 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EPX72871.1 - 0.0046 16.5 0.3 0.072 12.6 0.1 2.5 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EPX72871.1 - 0.025 14.4 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPX72871.1 - 0.027 14.4 0.0 0.084 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EPX72871.1 - 0.029 14.5 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EPX72871.1 - 0.052 13.2 0.0 0.17 11.6 0.0 1.8 1 1 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EPX72871.1 - 0.067 13.3 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 RNA helicase RuvB_N PF05496.7 EPX72871.1 - 0.071 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EPX72871.1 - 0.074 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 EPX72871.1 - 0.083 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EPX72871.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EPX72871.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 EPX72871.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EPX72871.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 EPX72871.1 - 0.19 10.5 0.0 0.35 9.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SLAC1 PF03595.12 EPX72872.1 - 2.2e-68 230.3 50.7 2.5e-68 230.1 35.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel E1_DerP2_DerF2 PF02221.10 EPX72873.1 - 8.3e-20 71.4 0.0 9.9e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EPX72873.1 - 0.0005 20.1 0.1 0.002 18.1 0.1 1.9 1 1 0 1 1 1 1 ML-like domain Myb_Cef PF11831.3 EPX72874.1 - 5.7e-40 136.9 8.9 5.7e-40 136.9 6.2 3.6 2 2 1 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EPX72874.1 - 6.5e-23 80.5 5.6 7e-12 45.2 0.4 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPX72874.1 - 5.9e-19 67.9 9.1 2.2e-13 50.0 2.7 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain ATC_hydrolase PF14196.1 EPX72874.1 - 0.12 12.7 2.0 9.4 6.6 0.4 3.0 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase DUF3215 PF11503.3 EPX72874.1 - 0.14 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) Yip1 PF04893.12 EPX72875.1 - 1.7e-10 40.7 13.7 2.2e-10 40.2 9.5 1.2 1 0 0 1 1 1 1 Yip1 domain Rad51 PF08423.6 EPX72876.1 - 1.5e-138 459.8 0.0 1.9e-138 459.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EPX72876.1 - 7.3e-14 51.6 0.0 1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EPX72876.1 - 8.8e-11 41.4 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EPX72876.1 - 1.6e-08 34.5 0.1 6.1e-08 32.7 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain KaiC PF06745.8 EPX72876.1 - 7.6e-07 28.4 0.0 1.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 EPX72876.1 - 0.02 13.7 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EPX72876.1 - 0.16 10.7 0.0 0.61 8.8 0.0 1.7 2 0 0 2 2 2 0 PAXNEB protein Ribosomal_60s PF00428.14 EPX72877.1 - 3.5e-25 88.2 10.7 4.2e-25 87.9 7.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein RRM_1 PF00076.17 EPX72878.1 - 2.1e-18 65.6 0.0 3.6e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 EPX72878.1 - 3.1e-16 59.2 0.1 8e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_6 PF14259.1 EPX72878.1 - 5.5e-11 42.2 0.0 1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EPX72878.1 - 2.1e-09 36.4 1.8 4.1e-09 35.5 1.2 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 EPX72878.1 - 3.9e-05 23.3 0.0 6.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L3 PF00297.17 EPX72879.1 - 5e-34 117.9 0.1 3.8e-33 114.9 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 TRAPP PF04051.11 EPX72880.1 - 1.4e-38 131.7 0.0 1.8e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PIG-L PF02585.12 EPX72881.1 - 7.1e-24 84.7 0.0 1e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase SPATA25 PF15218.1 EPX72881.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 2OG-FeII_Oxy_2 PF13532.1 EPX72882.1 - 1.2e-15 57.8 0.0 1.5e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EPX72882.1 - 7.8e-05 22.9 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_L22e PF01776.12 EPX72883.1 - 2.4e-46 156.3 1.8 2.8e-46 156.1 1.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF3808 PF10300.4 EPX72884.1 - 3.1e-109 365.6 2.0 3.8e-109 365.3 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 EPX72884.1 - 0.043 13.7 0.5 9 6.3 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat WW PF00397.21 EPX72885.1 - 0.055 13.3 0.4 0.055 13.3 0.3 1.9 2 0 0 2 2 2 0 WW domain Zip PF02535.17 EPX72885.1 - 0.14 11.1 5.5 0.2 10.6 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Alpha-amylase PF00128.19 EPX72886.1 - 8.7e-94 314.4 0.5 1.2e-93 313.9 0.3 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EPX72886.1 - 0.00019 21.5 0.1 0.00069 19.7 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Cep57_MT_bd PF06657.8 EPX72887.1 - 0.00035 20.4 6.5 0.00086 19.2 3.7 1.9 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 HrpB7 PF09486.5 EPX72887.1 - 0.0054 16.6 1.0 0.01 15.7 0.7 1.4 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Snapin_Pallidin PF14712.1 EPX72887.1 - 0.0089 16.3 1.5 0.0089 16.3 1.1 1.6 2 0 0 2 2 1 1 Snapin/Pallidin V_ATPase_I PF01496.14 EPX72887.1 - 0.014 13.2 1.1 0.017 13.0 0.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cauli_AT PF03233.8 EPX72887.1 - 0.019 14.6 0.6 0.024 14.3 0.4 1.2 1 0 0 1 1 1 0 Aphid transmission protein DUF2205 PF10224.4 EPX72887.1 - 0.019 14.5 2.1 0.028 13.9 1.5 1.4 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF4164 PF13747.1 EPX72887.1 - 0.021 14.9 1.4 0.034 14.2 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) CENP-H PF05837.7 EPX72887.1 - 0.032 14.4 1.1 0.055 13.6 0.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Prefoldin_2 PF01920.15 EPX72887.1 - 0.039 13.7 3.4 0.039 13.7 2.4 1.7 2 0 0 2 2 2 0 Prefoldin subunit DUF3450 PF11932.3 EPX72887.1 - 0.042 13.1 4.2 0.051 12.8 2.8 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) HTH_Crp_2 PF13545.1 EPX72887.1 - 0.05 13.4 0.1 0.091 12.5 0.0 1.5 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain NPV_P10 PF05531.7 EPX72887.1 - 0.053 13.7 0.4 0.082 13.1 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 EPX72887.1 - 0.086 12.3 2.3 0.11 12.0 1.6 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NpwBP PF12622.2 EPX72887.1 - 0.12 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 mRNA biogenesis factor DUF1002 PF06207.6 EPX72887.1 - 0.13 11.5 0.5 0.16 11.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) PilJ PF13675.1 EPX72887.1 - 0.14 12.5 2.9 0.31 11.3 1.6 1.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term IFT57 PF10498.4 EPX72887.1 - 0.14 10.8 4.2 0.17 10.6 2.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF342 PF03961.8 EPX72887.1 - 0.17 10.2 0.7 0.18 10.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CorA PF01544.13 EPX72887.1 - 0.17 10.8 3.0 0.19 10.6 2.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IncA PF04156.9 EPX72887.1 - 0.59 9.7 6.5 0.77 9.3 4.5 1.2 1 0 0 1 1 1 0 IncA protein Retrotrans_gag PF03732.12 EPX72887.1 - 0.66 10.0 3.2 0.83 9.7 1.3 1.9 1 1 1 2 2 2 0 Retrotransposon gag protein HALZ PF02183.13 EPX72887.1 - 0.98 9.1 6.8 0.54 10.0 1.7 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 EPX72887.1 - 1 9.7 4.7 1.5 9.1 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) H-kinase_dim PF02895.9 EPX72887.1 - 1.1 9.6 5.6 1.7 9.0 2.2 2.3 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain IGPS PF00218.16 EPX72889.1 - 3.9e-94 314.4 0.5 7.6e-94 313.5 0.3 1.5 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 EPX72889.1 - 4.3e-50 169.8 0.0 8.3e-50 168.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 EPX72889.1 - 6.6e-50 169.4 0.0 1.7e-46 158.2 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 EPX72889.1 - 7.6e-08 32.0 0.1 2.9e-07 30.1 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 EPX72889.1 - 0.0017 17.9 1.6 0.19 11.2 0.1 3.4 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain GATase_3 PF07685.9 EPX72889.1 - 0.064 12.8 0.2 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Arf PF00025.16 EPX72890.1 - 5.5e-73 243.9 0.1 6.4e-73 243.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EPX72890.1 - 1.9e-12 46.6 0.6 1.6e-08 33.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EPX72890.1 - 7.3e-12 44.8 0.0 8.9e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EPX72890.1 - 1.1e-11 44.4 0.0 1.3e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EPX72890.1 - 1.2e-09 37.7 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EPX72890.1 - 8.4e-07 29.5 0.0 1.2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPX72890.1 - 0.00045 20.1 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EPX72890.1 - 0.00082 18.5 0.4 0.009 15.1 0.1 2.0 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EPX72890.1 - 0.025 14.0 0.0 0.19 11.1 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain ADH_zinc_N PF00107.21 EPX72891.1 - 1.2e-28 99.2 0.8 1.7e-27 95.5 0.5 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPX72891.1 - 1.2e-26 92.6 0.4 3.4e-26 91.1 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPX72891.1 - 0.0024 18.7 0.0 0.0065 17.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPX72891.1 - 0.012 14.8 0.2 0.02 14.0 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EPX72891.1 - 0.02 14.2 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 EPX72891.1 - 0.038 14.1 0.1 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EPX72891.1 - 0.06 13.7 0.4 0.13 12.7 0.3 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 EPX72891.1 - 0.075 13.0 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pep_deformylase PF01327.16 EPX72891.1 - 0.089 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Polypeptide deformylase ThiF PF00899.16 EPX72891.1 - 0.24 11.2 4.6 2.6 7.8 1.7 2.4 1 1 1 2 2 2 0 ThiF family AlaDh_PNT_C PF01262.16 EPX72891.1 - 0.38 10.3 3.8 0.14 11.6 0.7 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ACBP PF00887.14 EPX72892.1 - 7e-30 102.5 0.9 7.6e-30 102.4 0.6 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Sec34 PF04136.10 EPX72893.1 - 3.5e-37 127.5 2.5 8.4e-37 126.2 0.7 2.4 2 0 0 2 2 2 1 Sec34-like family Xol-1_N PF09108.5 EPX72893.1 - 0.038 13.6 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Switch protein XOL-1, N-terminal TroA PF01297.12 EPX72893.1 - 0.24 10.6 1.4 2.8 7.1 0.4 2.3 2 0 0 2 2 2 0 Periplasmic solute binding protein family UPF0121 PF03661.8 EPX72894.1 - 1.3e-14 53.9 10.7 1.8e-14 53.5 7.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Lyase_1 PF00206.15 EPX72895.1 - 4.3e-100 334.9 0.0 7.6e-100 334.1 0.0 1.4 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.1 EPX72895.1 - 1.7e-26 92.0 0.0 3.5e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal TSLP PF15216.1 EPX72895.1 - 0.04 13.6 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Thymic stromal lymphopoietin RED_N PF07808.8 EPX72896.1 - 1.2e-07 31.2 1.3 2.5e-07 30.1 0.9 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region GvpG PF05120.7 EPX72896.1 - 0.24 11.2 2.3 0.31 10.8 0.0 2.3 3 0 0 3 3 3 0 Gas vesicle protein G Ribonucleas_3_3 PF14622.1 EPX72897.1 - 4.9e-21 75.0 0.0 6.5e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like SID PF11778.3 EPX72898.1 - 1.4e-21 76.8 0.1 3.1e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 Septation initiation NTR2 PF15458.1 EPX72898.1 - 0.009 15.2 0.9 0.023 13.9 0.7 1.7 1 0 0 1 1 1 1 Nineteen complex-related protein 2 TBPIP PF07106.8 EPX72898.1 - 0.17 11.4 5.2 2.6 7.5 0.5 2.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phage_GP20 PF06810.6 EPX72898.1 - 2.5 7.5 8.1 2.3 7.6 1.0 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 His_Phos_2 PF00328.17 EPX72899.1 - 4.9e-47 160.9 0.0 5.7e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) U3_assoc_6 PF08640.6 EPX72900.1 - 1.7e-27 95.0 4.2 5.6e-27 93.3 2.9 2.0 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 Coatomer_WDAD PF04053.9 EPX72901.1 - 2.1e-152 507.9 4.6 2.7e-152 507.6 1.3 2.3 2 1 1 3 3 3 1 Coatomer WD associated region WD40 PF00400.27 EPX72901.1 - 8.3e-51 168.1 5.0 1.1e-10 40.9 0.1 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EPX72901.1 - 0.018 13.3 0.2 0.24 9.6 0.1 2.7 3 1 0 3 3 3 0 Cytochrome D1 heme domain Clathrin PF00637.15 EPX72901.1 - 0.064 12.8 1.3 0.33 10.5 0.2 2.4 1 1 1 2 2 2 0 Region in Clathrin and VPS TPR_2 PF07719.12 EPX72901.1 - 1.4 9.0 5.9 0.75 9.8 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Las1 PF04031.8 EPX72902.1 - 5e-40 136.6 0.0 1.4e-39 135.2 0.0 1.8 1 0 0 1 1 1 1 Las1-like Ribosomal_L32e PF01655.13 EPX72903.1 - 9.4e-49 164.0 1.3 1.1e-48 163.8 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Chromo PF00385.19 EPX72904.1 - 1.8e-12 46.7 2.0 1.8e-12 46.7 1.4 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EPX72904.1 - 3.2e-10 39.6 0.1 1.1e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 Chromo shadow domain PMT PF02366.13 EPX72905.1 - 1.7e-83 279.7 23.9 1.7e-83 279.7 16.6 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EPX72905.1 - 1.7e-13 50.5 0.2 7.3e-13 48.4 0.1 1.9 1 1 1 2 2 2 2 MIR domain UCR_hinge PF02320.11 EPX72906.1 - 3.8e-19 68.3 8.0 9.3e-19 67.1 5.5 1.7 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein SprA-related PF12118.3 EPX72906.1 - 0.003 16.9 29.0 0.0037 16.6 20.1 1.1 1 0 0 1 1 1 1 SprA-related family FAM150 PF15129.1 EPX72906.1 - 0.25 11.2 9.4 1.6 8.6 6.5 2.5 1 1 0 1 1 1 0 FAM150 family Mitofilin PF09731.4 EPX72906.1 - 3.2 6.2 24.7 4.6 5.7 17.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AAA PF00004.24 EPX72907.1 - 2.3e-40 137.8 0.0 3.9e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPX72907.1 - 4.1e-06 26.9 0.0 0.00052 20.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPX72907.1 - 1.9e-05 24.3 0.0 7.5e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPX72907.1 - 0.00019 21.3 0.0 0.00063 19.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPX72907.1 - 0.00036 20.5 0.0 0.0014 18.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EPX72907.1 - 0.0021 17.0 0.0 0.0035 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EPX72907.1 - 0.0028 17.3 0.1 0.0084 15.8 0.1 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA_17 PF13207.1 EPX72907.1 - 0.0032 18.2 0.1 0.0072 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPX72907.1 - 0.0038 16.3 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EPX72907.1 - 0.0085 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPX72907.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPX72907.1 - 0.013 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPX72907.1 - 0.021 15.0 0.0 0.055 13.6 0.0 1.7 2 0 0 2 2 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EPX72907.1 - 0.028 14.4 0.0 0.071 13.1 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EPX72907.1 - 0.031 13.3 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EPX72907.1 - 0.041 13.2 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 EPX72907.1 - 0.044 13.3 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EPX72907.1 - 0.066 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EPX72907.1 - 0.067 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EPX72907.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EPX72907.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EPX72907.1 - 0.12 12.0 0.0 8 6.0 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase BNR PF02012.15 EPX72908.1 - 1.8e-10 39.0 46.9 1.5 8.9 0.0 12.2 13 0 0 13 13 13 9 BNR/Asp-box repeat BNR_2 PF13088.1 EPX72908.1 - 8.6e-10 38.3 0.8 0.26 10.5 0.0 6.1 6 1 0 6 6 6 4 BNR repeat-like domain PSII_BNR PF14870.1 EPX72908.1 - 0.0053 15.7 1.2 10 4.9 0.0 4.4 5 1 0 5 5 5 2 Photosynthesis system II assembly factor YCF48 SUI1 PF01253.17 EPX72909.1 - 1.8e-19 69.2 0.8 3.1e-19 68.5 0.6 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Packaging_FI PF14000.1 EPX72909.1 - 0.041 14.0 0.2 0.057 13.6 0.1 1.2 1 0 0 1 1 1 0 DNA packaging protein FI NUFIP1 PF10453.4 EPX72911.1 - 2e-14 52.8 7.3 4.8e-14 51.6 5.1 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) ABC_membrane PF00664.18 EPX72912.1 - 7.8e-104 346.9 40.5 1.4e-52 178.8 10.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPX72912.1 - 1.2e-66 223.2 0.0 1.1e-32 113.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EPX72912.1 - 3.4e-13 49.3 4.4 2.3e-05 23.7 0.1 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPX72912.1 - 1.4e-11 44.9 0.0 0.36 10.7 0.0 4.5 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EPX72912.1 - 1.7e-07 30.6 1.7 0.00093 18.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EPX72912.1 - 1.8e-07 31.3 0.1 0.033 14.1 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EPX72912.1 - 5.9e-07 30.3 0.0 0.053 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EPX72912.1 - 6.4e-07 28.3 1.5 0.00034 19.3 0.0 3.1 3 0 0 3 3 3 1 Predicted ATPase of the ABC class DUF258 PF03193.11 EPX72912.1 - 1.5e-05 24.2 1.0 0.19 10.8 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EPX72912.1 - 6.7e-05 22.3 0.7 0.2 11.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 EPX72912.1 - 0.0002 21.1 2.5 0.27 11.1 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EPX72912.1 - 0.00024 21.2 4.6 0.3 11.2 0.0 4.1 3 2 0 3 3 2 2 AAA domain AAA_23 PF13476.1 EPX72912.1 - 0.00094 19.5 0.4 0.51 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EPX72912.1 - 0.0016 17.8 0.2 1.6 8.1 0.0 3.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EPX72912.1 - 0.0047 16.7 1.1 3.8 7.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPX72912.1 - 0.0069 16.6 0.0 5.8 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EPX72912.1 - 0.0069 16.2 0.0 1.7 8.5 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 EPX72912.1 - 0.01 15.5 0.1 1.8 8.3 0.0 3.1 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 EPX72912.1 - 0.011 14.8 0.6 8 5.4 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin AAA_30 PF13604.1 EPX72912.1 - 0.011 15.3 8.2 1.5 8.3 0.0 4.2 5 1 0 5 5 4 0 AAA domain DUF87 PF01935.12 EPX72912.1 - 0.011 15.5 1.0 1.7 8.3 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_5 PF07728.9 EPX72912.1 - 0.013 15.1 0.2 11 5.6 0.0 3.7 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 EPX72912.1 - 0.031 12.9 0.2 2.9 6.4 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit AAA_10 PF12846.2 EPX72912.1 - 0.04 13.3 2.4 5.7 6.2 0.0 3.3 4 0 0 4 4 4 0 AAA-like domain MobB PF03205.9 EPX72912.1 - 0.044 13.4 0.5 8.6 6.0 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EPX72912.1 - 0.14 11.0 0.4 11 4.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.20 EPX72912.1 - 0.16 11.4 2.1 0.82 9.1 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 EPX72912.1 - 0.37 10.7 5.2 3.9 7.4 0.2 3.2 2 1 1 3 3 3 0 AAA domain DUF1162 PF06650.7 EPX72913.1 - 2e-60 204.3 8.4 6.3e-59 199.4 0.2 4.4 4 1 0 4 4 4 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EPX72913.1 - 6e-37 125.7 3.4 9e-37 125.2 0.3 2.8 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EPX72913.1 - 0.00028 20.9 0.0 0.00075 19.6 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain EcsC PF12787.2 EPX72914.1 - 0.098 12.0 0.2 0.15 11.4 0.1 1.3 1 1 0 1 1 1 0 EcsC protein family DUF4473 PF14747.1 EPX72914.1 - 0.16 12.2 1.4 0.23 11.6 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) SET PF00856.23 EPX72915.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.7 1 1 0 1 1 1 0 SET domain DUF544 PF04424.8 EPX72916.1 - 2.2e-16 59.7 0.0 3.9e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) WD40 PF00400.27 EPX72917.1 - 0.00013 21.7 1.8 8.4 6.4 0.1 4.7 4 1 0 4 4 4 2 WD domain, G-beta repeat DUF4221 PF13970.1 EPX72917.1 - 0.029 13.7 0.3 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4221) DUF2665 PF11654.3 EPX72919.1 - 1.8e-20 72.2 0.2 2.1e-20 72.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) Ribosomal_L6 PF00347.18 EPX72920.1 - 4.4e-35 120.0 1.2 1.3e-19 70.5 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF2385 PF09539.5 EPX72921.1 - 0.33 11.3 6.1 0.21 11.9 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2385) RTC PF01137.16 EPX72922.1 - 3.3e-67 225.6 0.0 4.1e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EPX72922.1 - 6.6e-32 109.5 0.0 1e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Cpn60_TCP1 PF00118.19 EPX72923.1 - 1.8e-116 389.6 5.6 2.1e-116 389.4 3.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TFIID-31kDa PF02291.10 EPX72924.1 - 4.7e-55 184.8 0.0 6.2e-55 184.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EPX72924.1 - 0.085 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 RRM_6 PF14259.1 EPX72925.1 - 3.6e-07 30.0 0.0 7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX72925.1 - 6.4e-07 28.9 0.1 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX72925.1 - 7.2e-07 28.9 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EPX72926.1 - 0.042 13.7 2.3 17 5.5 0.0 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF2361 PF10153.4 EPX72927.1 - 9.8e-34 115.9 15.1 9.8e-34 115.9 10.5 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) V-SNARE PF05008.10 EPX72927.1 - 2.2 8.5 7.6 3.8 7.7 2.2 3.2 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Actin PF00022.14 EPX72929.1 - 1.6e-85 286.8 0.0 4.1e-85 285.5 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPX72929.1 - 0.00053 18.6 0.0 0.3 9.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein WBP-1 PF11669.3 EPX72930.1 - 0.00063 19.7 0.1 0.0015 18.5 0.0 1.6 2 0 0 2 2 2 1 WW domain-binding protein 1 TMEM61 PF15105.1 EPX72930.1 - 0.0056 16.2 1.1 0.0084 15.6 0.8 1.3 1 0 0 1 1 1 1 TMEM61 protein family WWbp PF10349.4 EPX72930.1 - 0.047 14.5 0.7 0.069 14.0 0.5 1.1 1 0 0 1 1 1 0 WW-domain ligand protein MLANA PF14991.1 EPX72930.1 - 0.065 13.2 0.0 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein melan-A FtsJ PF01728.14 EPX72931.1 - 7.2e-67 224.8 0.0 8.5e-67 224.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EPX72931.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PTPA PF03095.10 EPX72932.1 - 5.7e-107 357.3 0.0 6.6e-107 357.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein BPL_LplA_LipB PF03099.14 EPX72933.1 - 1.6e-16 60.4 0.0 2.8e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BUD22 PF09073.5 EPX72934.1 - 4.8e-60 203.8 40.0 2.2e-59 201.6 27.7 1.8 1 1 0 1 1 1 1 BUD22 ATG13 PF10033.4 EPX72935.1 - 3.5e-61 206.6 1.0 3.8e-61 206.4 0.1 1.5 2 0 0 2 2 2 1 Autophagy-related protein 13 CBF PF03914.12 EPX72936.1 - 3.7e-42 143.5 0.1 3.7e-42 143.5 0.0 2.7 3 0 0 3 3 3 1 CBF/Mak21 family PXA PF02194.10 EPX72936.1 - 0.31 10.5 4.5 1.1 8.7 0.5 2.8 2 0 0 2 2 2 0 PXA domain Anp1 PF03452.9 EPX72937.1 - 7.1e-101 336.8 0.0 8.6e-101 336.6 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EPX72937.1 - 0.0028 17.3 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Snurportin1 PF11538.3 EPX72937.1 - 0.18 11.5 0.8 0.38 10.5 0.6 1.4 1 0 0 1 1 1 0 Snurportin1 Septin PF00735.13 EPX72938.1 - 1.4e-102 342.4 0.1 1.4e-102 342.4 0.1 1.7 2 0 0 2 2 2 1 Septin GTP_EFTU PF00009.22 EPX72938.1 - 1.1e-07 31.4 0.2 0.00022 20.7 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPX72938.1 - 7.2e-07 29.1 0.0 1.7e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPX72938.1 - 2e-05 23.8 0.0 4.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EPX72938.1 - 0.00021 20.4 0.0 0.00021 20.4 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_10 PF12846.2 EPX72938.1 - 0.00022 20.7 0.3 0.00059 19.3 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EPX72938.1 - 0.00038 20.5 0.3 0.001 19.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EPX72938.1 - 0.0005 19.6 0.3 0.0012 18.3 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family PduV-EutP PF10662.4 EPX72938.1 - 0.0021 17.5 0.2 0.35 10.3 0.0 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EPX72938.1 - 0.0031 17.0 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EPX72938.1 - 0.0044 17.1 0.0 0.022 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EPX72938.1 - 0.0066 16.2 0.2 0.0066 16.2 0.1 2.8 2 1 1 3 3 3 1 Dynamin family ABC_tran PF00005.22 EPX72938.1 - 0.0067 16.7 0.0 0.0067 16.7 0.0 2.7 2 1 0 2 2 2 1 ABC transporter Gtr1_RagA PF04670.7 EPX72938.1 - 0.0095 15.0 0.7 0.035 13.2 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region DUF87 PF01935.12 EPX72938.1 - 0.013 15.3 6.4 0.021 14.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 T2SE PF00437.15 EPX72938.1 - 0.014 14.3 0.6 0.074 11.9 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EPX72938.1 - 0.027 13.9 0.1 0.22 10.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EPX72938.1 - 0.034 14.6 0.0 0.034 14.6 0.0 2.8 4 0 0 4 4 3 0 Miro-like protein AAA_32 PF13654.1 EPX72938.1 - 0.037 12.7 6.8 0.2 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EPX72938.1 - 0.065 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Exonuc_VII_L PF02601.10 EPX72938.1 - 0.49 9.5 6.8 0.94 8.6 4.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_18 PF13238.1 EPX72938.1 - 0.69 10.2 4.1 1.7 8.9 0.0 3.0 2 1 1 3 3 3 0 AAA domain CENP-L PF13092.1 EPX72939.1 - 6.7e-22 78.0 1.8 1.2e-21 77.1 0.6 1.8 2 0 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 GYF PF02213.11 EPX72940.1 - 3.8e-18 64.8 0.3 8.6e-18 63.6 0.2 1.7 1 0 0 1 1 1 1 GYF domain NAC PF01849.13 EPX72941.1 - 2e-19 68.8 1.0 2.1e-19 68.7 0.1 1.5 2 0 0 2 2 2 1 NAC domain DUF236 PF03057.9 EPX72941.1 - 0.034 14.1 0.5 0.056 13.4 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function WH1 PF00568.18 EPX72942.1 - 3.6e-22 78.1 0.0 5.4e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 WH1 domain E1-E2_ATPase PF00122.15 EPX72943.1 - 4.7e-15 55.2 0.9 1.2e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EPX72943.1 - 1.4e-13 51.4 0.0 3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPX72943.1 - 2.7e-13 50.8 0.0 6.1e-12 46.4 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPX72943.1 - 1.8e-11 43.8 0.0 5e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPX72943.1 - 0.00048 19.7 0.2 0.0017 18.0 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_13 PF13166.1 EPX72944.1 - 0.0047 15.4 5.0 0.0057 15.1 3.4 1.0 1 0 0 1 1 1 1 AAA domain KorB PF08535.5 EPX72944.1 - 0.0071 16.4 0.5 0.013 15.6 0.3 1.4 1 0 0 1 1 1 1 KorB domain ApoLp-III PF07464.6 EPX72944.1 - 0.015 15.3 8.4 0.02 14.9 5.8 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF445 PF04286.7 EPX72944.1 - 0.016 14.7 2.4 0.019 14.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Syntaxin_2 PF14523.1 EPX72944.1 - 0.02 14.8 4.9 0.029 14.4 3.4 1.2 1 0 0 1 1 1 0 Syntaxin-like protein DUF651 PF04895.7 EPX72944.1 - 0.023 14.3 1.4 0.063 12.9 0.2 1.9 1 1 1 2 2 2 0 Archaeal protein of unknown function (DUF651) Relaxase PF03432.9 EPX72944.1 - 0.032 13.6 5.9 0.054 12.8 4.0 1.5 1 1 0 1 1 1 0 Relaxase/Mobilisation nuclease domain DUF2408 PF10303.4 EPX72944.1 - 0.061 13.4 1.7 0.081 13.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) OmpH PF03938.9 EPX72944.1 - 0.29 11.0 8.7 0.38 10.6 6.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YpjP PF14005.1 EPX72944.1 - 0.35 10.6 2.6 0.47 10.2 1.8 1.4 1 1 0 1 1 1 0 YpjP-like protein DUF883 PF05957.8 EPX72944.1 - 0.87 10.0 5.7 11 6.4 3.3 2.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Atg14 PF10186.4 EPX72944.1 - 1.7 7.5 7.0 2 7.2 4.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Vfa1 PF08432.5 EPX72944.1 - 2.8 7.9 13.1 3.3 7.6 9.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.12 EPX72944.1 - 2.9 7.6 6.9 3.4 7.4 4.8 1.1 1 0 0 1 1 1 0 DDHD domain IncA PF04156.9 EPX72944.1 - 7.7 6.0 8.0 11 5.5 5.6 1.1 1 0 0 1 1 1 0 IncA protein YtxH PF12732.2 EPX72944.1 - 9 6.7 15.4 1.4e+03 -0.4 10.7 2.5 1 1 0 1 1 1 0 YtxH-like protein WD40 PF00400.27 EPX72945.1 - 3.9e-10 39.2 0.0 0.00078 19.2 0.1 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat E7 PF00527.13 EPX72945.1 - 0.04 14.0 0.6 0.075 13.1 0.4 1.4 1 0 0 1 1 1 0 E7 protein, Early protein zf-HIT PF04438.11 EPX72946.1 - 1.9e-11 43.4 13.0 3e-11 42.7 9.0 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-C2H2_4 PF13894.1 EPX72946.1 - 4.9 7.7 9.1 11 6.6 6.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Glutaredoxin PF00462.19 EPX72947.1 - 1.8e-16 59.8 0.3 2.2e-16 59.5 0.2 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EPX72947.1 - 0.00059 20.0 0.4 0.0011 19.1 0.3 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EPX72947.1 - 0.00088 19.0 0.1 0.0012 18.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.1 EPX72947.1 - 0.0022 18.0 1.1 0.22 11.4 0.4 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_9 PF14595.1 EPX72947.1 - 0.0027 17.2 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EPX72947.1 - 0.0057 16.6 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DUF3083 PF11281.3 EPX72947.1 - 0.013 14.6 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) Zn_ribbon_2 PF12674.2 EPX72947.1 - 0.045 14.1 0.0 0.058 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative zinc ribbon domain GST_N_2 PF13409.1 EPX72947.1 - 0.049 13.6 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Tox-PL-2 PF15643.1 EPX72947.1 - 0.062 13.2 0.1 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Papain fold toxin 2 DSBA PF01323.15 EPX72947.1 - 0.092 12.2 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 DSBA-like thioredoxin domain DUF836 PF05768.9 EPX72947.1 - 0.12 12.5 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TPR_11 PF13414.1 EPX72948.1 - 2.9e-14 52.4 2.3 2.4e-07 30.2 0.0 4.7 4 1 1 5 5 5 2 TPR repeat TPR_14 PF13428.1 EPX72948.1 - 3.5e-10 39.5 0.0 0.39 11.4 0.0 6.3 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPX72948.1 - 8.9e-10 37.7 0.1 0.00049 19.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPX72948.1 - 3.7e-08 32.9 0.1 0.016 15.3 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPX72948.1 - 5.4e-07 29.0 0.5 0.0016 18.1 0.0 3.8 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPX72948.1 - 1.5e-05 24.4 0.5 0.11 12.3 0.0 4.0 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPX72948.1 - 3.6e-05 24.0 0.4 0.054 13.8 0.0 4.7 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPX72948.1 - 4.9e-05 23.8 0.0 0.005 17.4 0.0 4.3 4 1 3 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPX72948.1 - 0.00013 21.7 0.0 0.1 12.5 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPX72948.1 - 0.018 15.0 5.6 6 6.8 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPX72948.1 - 0.04 14.3 0.7 74 4.1 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EPX72948.1 - 0.043 13.9 0.1 3.4 7.8 0.0 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 EPX72948.1 - 0.043 13.1 0.1 6.9 6.0 0.0 3.0 3 0 0 3 3 3 0 26S proteasome subunit RPN7 DUF1903 PF08991.5 EPX72949.1 - 4.5e-18 65.1 10.7 4.9e-18 65.0 7.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EPX72949.1 - 0.8 9.6 10.7 1.8 8.5 7.4 1.6 1 0 0 1 1 1 0 CHCH domain Cmc1 PF08583.5 EPX72949.1 - 2.2 8.1 9.0 0.51 10.1 1.0 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Brr6_like_C_C PF10104.4 EPX72949.1 - 4.2 6.8 6.8 4.1 6.9 4.7 1.2 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Glyco_hydro_72 PF03198.9 EPX72950.1 - 4.7e-131 436.4 6.3 6.7e-131 435.9 4.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EPX72950.1 - 5e-21 74.9 6.8 1.6e-20 73.3 4.7 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EPX72950.1 - 0.00016 20.9 0.4 0.00062 19.0 0.3 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EPX72950.1 - 0.019 13.8 0.4 0.056 12.3 0.3 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glucan_synthase PF02364.10 EPX72951.1 - 0 1305.3 0.2 0 1304.9 0.1 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EPX72951.1 - 8e-37 125.7 1.2 1.7e-36 124.6 0.8 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Ribosomal_S30 PF04758.9 EPX72952.1 - 7.9e-30 102.3 5.0 8.6e-30 102.2 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 NIF PF03031.13 EPX72953.1 - 3.1e-27 95.2 0.3 1e-26 93.4 0.0 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EPX72953.1 - 2.3e-09 36.9 0.0 5.8e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EPX72953.1 - 0.00031 20.8 0.0 0.00096 19.2 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HAD_2 PF13419.1 EPX72953.1 - 0.046 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Rhomboid PF01694.17 EPX72954.1 - 7.3e-09 35.7 13.0 7.3e-09 35.7 9.0 1.9 1 1 1 2 2 2 1 Rhomboid family zf-C2H2_2 PF12756.2 EPX72955.1 - 1.4e-17 63.6 12.2 2.7e-15 56.2 2.7 2.9 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 EPX72955.1 - 0.011 15.7 21.3 1.6 8.9 0.2 4.3 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DUF1474 PF07342.6 EPX72955.1 - 0.14 12.4 2.5 0.21 11.8 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1474) DUF3279 PF11682.3 EPX72955.1 - 0.56 9.7 3.5 12 5.4 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3279) Elf1 PF05129.8 EPX72955.1 - 2.9 7.6 8.6 6.7 6.4 0.1 3.1 3 1 0 3 3 3 0 Transcription elongation factor Elf1 like Peptidase_C54 PF03416.14 EPX72956.1 - 7.6e-74 248.3 0.0 2.3e-73 246.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 EPX72956.1 - 0.011 14.8 0.1 0.32 10.0 0.0 2.6 2 1 1 3 3 3 0 Peptidase family C78 SRP14 PF02290.10 EPX72957.1 - 1.4e-17 63.3 2.0 2.3e-17 62.6 0.0 2.2 2 1 0 2 2 2 1 Signal recognition particle 14kD protein Thioredoxin_5 PF13743.1 EPX72957.1 - 0.051 13.1 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin JAB PF01398.16 EPX72958.1 - 4.9e-18 64.9 0.1 1.7e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EPX72958.1 - 8.1e-07 28.5 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 EPX72958.1 - 0.00024 21.0 0.3 0.00049 20.0 0.2 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain zf-C2H2_jaz PF12171.3 EPX72959.1 - 1.1e-08 34.9 1.0 1.1e-08 34.9 0.7 1.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EPX72959.1 - 0.034 14.2 0.9 0.041 13.9 0.2 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EPX72959.1 - 0.039 14.1 0.6 0.065 13.4 0.4 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Pkinase PF00069.20 EPX72961.1 - 1.9e-70 237.0 0.0 3.1e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX72961.1 - 6.6e-34 117.1 0.0 1.2e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX72961.1 - 0.028 14.1 0.0 0.59 9.8 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family dUTPase PF00692.14 EPX72962.1 - 4.1e-43 145.9 0.0 4.5e-43 145.7 0.0 1.0 1 0 0 1 1 1 1 dUTPase mRNA_triPase PF02940.10 EPX72963.1 - 2e-56 191.1 0.1 3.1e-56 190.5 0.1 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Snf7 PF03357.16 EPX72964.1 - 2.5e-31 108.3 20.6 2.5e-31 108.3 14.2 1.4 1 1 1 2 2 2 1 Snf7 Peptidase_S46 PF10459.4 EPX72964.1 - 0.092 11.1 8.1 0.11 10.8 5.6 1.3 1 1 0 1 1 1 0 Peptidase S46 DUF4400 PF14348.1 EPX72964.1 - 0.17 11.2 0.4 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) REV PF00424.13 EPX72964.1 - 0.28 11.0 6.4 4 7.3 0.8 2.8 1 1 2 3 3 3 0 REV protein (anti-repression trans-activator protein) SOBP PF15279.1 EPX72964.1 - 0.49 10.7 2.3 0.57 10.5 1.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein YlqD PF11068.3 EPX72964.1 - 0.79 9.7 13.5 9.1 6.3 3.1 2.2 1 1 1 2 2 2 0 YlqD protein Hpt PF01627.18 EPX72964.1 - 1.9 8.5 8.4 0.13 12.2 1.7 2.3 3 2 0 3 3 3 0 Hpt domain HSCB_C PF07743.8 EPX72964.1 - 5.3 7.5 17.1 1.3 9.5 1.9 2.9 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF87 PF01935.12 EPX72964.1 - 7.8 6.2 8.2 14 5.4 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 KOW PF00467.24 EPX72965.1 - 5.7e-05 22.6 0.1 0.00013 21.5 0.1 1.6 1 0 0 1 1 1 1 KOW motif SBDS_C PF09377.5 EPX72966.1 - 3.3e-39 133.4 0.1 5.7e-39 132.6 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EPX72966.1 - 4.3e-34 116.1 2.0 4.3e-34 116.1 1.4 1.7 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Brix PF04427.13 EPX72967.1 - 2.5e-40 138.2 0.2 3.6e-40 137.6 0.2 1.2 1 0 0 1 1 1 1 Brix domain DUF4337 PF14235.1 EPX72967.1 - 3.8 7.3 6.7 6.3 6.6 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MRP-L28 PF09812.4 EPX72968.1 - 8.6e-19 67.9 1.4 1.1e-18 67.6 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF3233 PF11557.3 EPX72968.1 - 0.033 13.0 0.1 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3233) Hemagglutinin PF00509.13 EPX72968.1 - 0.061 11.4 0.1 0.064 11.4 0.1 1.1 1 0 0 1 1 1 0 Haemagglutinin Ribosom_S12_S23 PF00164.20 EPX72969.1 - 2.6e-45 152.7 2.5 3.3e-45 152.4 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Hexokinase_2 PF03727.11 EPX72970.1 - 5.7e-73 245.1 0.0 7.6e-73 244.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EPX72970.1 - 6.1e-68 228.1 0.0 9.5e-68 227.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Asp-Al_Ex PF06826.7 EPX72970.1 - 0.035 13.6 0.1 0.068 12.6 0.1 1.4 1 0 0 1 1 1 0 Predicted Permease Membrane Region EI24 PF07264.6 EPX72971.1 - 0.0032 16.9 2.6 0.0035 16.7 1.8 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2207 PF09972.4 EPX72971.1 - 0.012 14.1 4.7 0.016 13.8 3.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tetraspannin PF00335.15 EPX72971.1 - 0.046 12.9 2.4 0.055 12.7 1.7 1.1 1 0 0 1 1 1 0 Tetraspanin family RRN7 PF11781.3 EPX72971.1 - 0.052 13.0 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 CH PF00307.26 EPX72972.1 - 8e-13 48.3 0.0 1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain RIG-I_C-RD PF11648.3 EPX72972.1 - 0.00084 19.2 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I CAMSAP_CH PF11971.3 EPX72972.1 - 0.018 14.6 0.1 0.039 13.6 0.0 1.5 1 1 0 1 1 1 0 CAMSAP CH domain WD40 PF00400.27 EPX72973.1 - 6.9e-29 98.6 21.1 4.4e-09 35.8 0.1 8.5 9 0 0 9 9 9 5 WD domain, G-beta repeat zf-RING_2 PF13639.1 EPX72973.1 - 0.03 14.1 9.5 0.061 13.1 6.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EPX72973.1 - 0.35 10.9 8.8 0.73 9.9 6.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EPX72973.1 - 2.3 8.3 7.2 6.8 6.8 5.0 1.9 1 1 0 1 1 1 0 RING-variant domain PROCN PF08083.6 EPX72974.1 - 2.2e-223 741.1 5.8 3.6e-223 740.4 4.0 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EPX72974.1 - 1.9e-125 416.7 1.2 3.6e-125 415.8 0.9 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EPX72974.1 - 2.9e-91 303.0 1.8 8.7e-91 301.4 1.3 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EPX72974.1 - 6.6e-76 253.1 1.3 1.6e-75 251.8 0.9 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EPX72974.1 - 4.7e-68 227.0 0.1 1e-67 225.9 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EPX72974.1 - 2.5e-43 146.7 0.0 5.8e-43 145.5 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 EPX72974.1 - 6.8e-42 141.2 0.0 1.8e-41 139.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 EPX72974.1 - 9.2e-09 35.0 0.0 2.3e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RasGAP_C PF03836.10 EPX72975.1 - 3.1e-46 156.6 2.6 7.6e-46 155.3 1.8 1.7 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EPX72975.1 - 2.2e-25 89.4 0.4 2.2e-25 89.4 0.3 3.0 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EPX72975.1 - 8.5e-15 52.9 11.7 0.19 11.4 0.0 11.1 11 0 0 11 11 11 4 IQ calmodulin-binding motif CH PF00307.26 EPX72975.1 - 1.1e-13 51.1 0.1 6.4e-13 48.6 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain HMG_CoA_synt_C PF08540.5 EPX72976.1 - 2.2e-109 365.3 0.6 2.8e-109 364.9 0.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EPX72976.1 - 7.6e-83 276.2 1.1 2.4e-82 274.6 0.3 2.1 2 1 1 3 3 3 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Sugar_tr PF00083.19 EPX72977.1 - 1.3e-110 370.1 23.3 1.5e-110 369.8 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPX72977.1 - 8e-27 93.8 20.3 8e-27 93.8 14.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPX72977.1 - 4.8e-09 34.9 5.1 4.8e-09 34.9 3.5 2.4 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EPX72977.1 - 0.00078 17.6 1.4 0.00078 17.6 1.0 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector SH3_1 PF00018.23 EPX72978.1 - 4.6e-13 48.3 0.0 1.1e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPX72978.1 - 3.6e-11 42.4 0.0 6.5e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPX72978.1 - 2.4e-08 33.3 0.0 4.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.18 EPX72978.1 - 0.045 13.9 2.7 0.052 13.7 0.3 2.1 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF1765 PF08578.5 EPX72979.1 - 4.7e-21 75.1 7.5 4.7e-21 75.1 5.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) ATG11 PF10377.4 EPX72980.1 - 3.4e-29 101.3 0.3 3.4e-29 101.3 0.2 2.5 2 0 0 2 2 2 1 Autophagy-related protein 11 Geminin PF07412.7 EPX72980.1 - 0.00072 19.3 1.6 0.00072 19.3 1.1 3.4 3 1 0 3 3 3 1 Geminin Snapin_Pallidin PF14712.1 EPX72980.1 - 0.0052 17.0 1.6 0.0052 17.0 1.1 4.6 3 1 2 5 5 5 1 Snapin/Pallidin H-kinase_dim PF02895.9 EPX72980.1 - 0.08 13.2 1.3 9.3 6.6 0.1 4.4 3 2 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain DUF948 PF06103.6 EPX72980.1 - 0.086 12.7 4.4 4.6 7.1 0.1 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HAD_2 PF13419.1 EPX72981.1 - 5.2e-21 75.6 0.0 6e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPX72981.1 - 1.1e-07 31.3 0.0 2.1e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EPX72981.1 - 5.3e-05 23.7 0.0 0.043 14.2 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase ALG3 PF05208.8 EPX72982.1 - 5.2e-129 430.6 30.8 6.2e-129 430.4 21.3 1.0 1 0 0 1 1 1 1 ALG3 protein Thioredoxin PF00085.15 EPX72983.1 - 1.9e-30 104.5 0.7 2.2e-30 104.4 0.5 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EPX72983.1 - 5.7e-09 36.1 0.2 4.4e-08 33.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPX72983.1 - 1.9e-08 34.3 0.1 4.2e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EPX72983.1 - 1.6e-05 24.4 0.2 0.00012 21.6 0.1 1.8 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 EPX72983.1 - 3.5e-05 23.4 0.2 4.1e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_4 PF13462.1 EPX72983.1 - 0.00033 20.6 0.2 0.029 14.3 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.1 EPX72983.1 - 0.00043 20.2 0.1 0.00068 19.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EPX72983.1 - 0.0022 17.5 0.1 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.1 EPX72983.1 - 0.02 14.3 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF2847 PF11009.3 EPX72983.1 - 0.038 13.5 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Glutaredoxin PF00462.19 EPX72983.1 - 0.13 12.2 0.1 0.21 11.6 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin Ost4 PF10215.4 EPX72984.1 - 4.6e-11 42.0 0.0 4.6e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccaryltransferase Steroid_dh PF02544.11 EPX72985.1 - 5.3e-09 35.9 9.0 5.3e-09 35.9 6.3 2.0 1 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2393 PF09624.5 EPX72985.1 - 0.14 11.7 1.4 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) V-ATPase_H_N PF03224.9 EPX72986.1 - 2.4e-52 178.0 4.1 2.7e-52 177.8 1.6 2.0 2 1 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EPX72986.1 - 4.9e-45 152.2 1.4 3.5e-43 146.3 0.3 2.8 3 0 0 3 3 3 1 V-ATPase subunit H HEAT PF02985.17 EPX72986.1 - 1.3e-06 27.9 0.1 0.012 15.6 0.0 3.4 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.1 EPX72986.1 - 2.8e-05 24.2 0.0 0.093 13.0 0.0 2.7 2 1 1 3 3 3 3 HEAT repeats Arm PF00514.18 EPX72986.1 - 0.0025 17.5 0.0 0.041 13.7 0.0 3.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Mito_carr PF00153.22 EPX72986.1 - 0.05 13.2 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial carrier protein Sec39 PF08314.6 EPX72987.1 - 4.5e-85 286.0 22.3 4.5e-85 286.0 15.5 1.5 1 1 1 2 2 2 1 Secretory pathway protein Sec39 Cullin_binding PF03556.10 EPX72987.1 - 0.00084 19.4 1.9 0.0078 16.3 0.1 2.7 2 0 0 2 2 2 1 Cullin binding DUF1212 PF06738.7 EPX72988.1 - 2.4e-49 167.4 10.3 3.4e-46 157.1 0.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EPX72988.1 - 2.2e-23 82.5 8.7 2.2e-23 82.5 6.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) SurA_N PF09312.6 EPX72989.1 - 0.085 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 SurA N-terminal domain WD40 PF00400.27 EPX72991.1 - 8.3e-18 63.5 0.6 1.1e-08 34.5 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 EPX72991.1 - 0.0017 18.1 0.1 0.21 11.2 0.0 2.6 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A BBS2_N PF14781.1 EPX72991.1 - 0.0039 16.8 0.0 0.26 10.9 0.0 2.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal Apc4_WD40 PF12894.2 EPX72991.1 - 0.025 14.0 0.0 1.5 8.3 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.10 EPX72991.1 - 0.031 13.3 0.0 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 CPSF A subunit region Metallophos PF00149.23 EPX72992.1 - 1.7e-43 148.3 3.2 2.1e-43 148.0 2.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HAD PF12710.2 EPX72993.1 - 5e-15 56.1 0.0 7.2e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EPX72993.1 - 4.8e-09 35.7 0.1 1.9e-08 33.7 0.1 1.7 1 1 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 EPX72993.1 - 2.9e-06 27.6 0.0 2e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPX72993.1 - 2.1e-05 25.0 0.0 0.00053 20.4 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EPX72993.1 - 3.1e-05 23.4 0.0 8.4e-05 22.0 0.0 1.7 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) ParBc_2 PF08857.6 EPX72993.1 - 0.095 12.5 0.1 0.39 10.5 0.0 2.1 1 1 1 2 2 2 0 Putative ParB-like nuclease TPR_1 PF00515.23 EPX72993.1 - 0.15 11.7 0.2 0.6 9.8 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat She9_MDM33 PF05546.6 EPX72994.1 - 4.8e-75 251.6 14.4 6.9e-75 251.1 10.0 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EPX72994.1 - 0.038 13.5 0.5 0.078 12.5 0.4 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein ASL_C2 PF14698.1 EPX72994.1 - 0.21 11.6 1.0 3.8 7.6 0.1 3.0 3 0 0 3 3 3 0 Argininosuccinate lyase C-terminal T4SS PF07996.6 EPX72994.1 - 1.2 8.9 8.7 7.1 6.4 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion system proteins DUF904 PF06005.7 EPX72994.1 - 2.5 8.4 14.7 4.9 7.5 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Clathrin PF00637.15 EPX72995.1 - 3.7e-09 36.3 5.9 1.2e-07 31.4 0.1 3.4 4 0 0 4 4 4 2 Region in Clathrin and VPS Cytokin_check_N PF10407.4 EPX72995.1 - 0.03 13.9 0.2 0.14 11.8 0.0 2.3 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus zf-rbx1 PF12678.2 EPX72995.1 - 0.084 12.9 2.4 0.21 11.6 1.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPX72995.1 - 0.28 11.2 8.3 0.77 9.8 5.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPX72995.1 - 0.81 9.5 8.3 2.4 8.0 5.7 1.8 1 0 0 1 1 1 0 Ring finger domain PAP2 PF01569.16 EPX72996.1 - 2e-15 56.6 3.1 6.8e-15 54.8 2.1 2.0 1 1 0 1 1 1 1 PAP2 superfamily Mito_carr PF00153.22 EPX72997.1 - 4.4e-57 189.7 0.4 4.3e-19 68.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Asparaginase_2 PF01112.13 EPX72998.1 - 2.1e-24 85.8 0.1 6.4e-24 84.2 0.1 1.7 1 1 0 1 1 1 1 Asparaginase DEAD PF00270.24 EPX72999.1 - 3.1e-48 163.4 0.0 5.2e-48 162.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX72999.1 - 3e-26 91.0 0.0 7.9e-26 89.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX72999.1 - 1.7e-07 31.2 0.0 8.2e-07 29.0 0.0 2.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Per1 PF04080.8 EPX73000.1 - 2.3e-94 315.7 12.4 3.1e-94 315.3 8.6 1.1 1 0 0 1 1 1 1 Per1-like BPD_transp_2 PF02653.11 EPX73000.1 - 0.16 10.8 9.1 0.3 10.0 6.3 1.3 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Ycf1 PF05758.7 EPX73001.1 - 0.012 13.4 0.1 0.017 12.9 0.1 1.2 1 0 0 1 1 1 0 Ycf1 YqfD PF06898.6 EPX73001.1 - 0.06 12.0 0.3 0.071 11.8 0.2 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Bromo_TP PF07524.8 EPX73002.1 - 9.1e-19 66.9 0.2 1.5e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated SNARE PF05739.14 EPX73003.1 - 2.6e-18 65.4 2.7 2.6e-18 65.4 1.9 3.2 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 EPX73003.1 - 0.00021 21.4 4.3 0.00021 21.4 3.0 2.9 1 1 1 2 2 2 1 Syntaxin Cor1 PF04803.7 EPX73003.1 - 0.16 11.7 8.9 0.57 9.9 3.9 2.9 1 1 2 3 3 3 0 Cor1/Xlr/Xmr conserved region Med11 PF10280.4 EPX73003.1 - 0.75 9.8 8.2 24 5.0 5.7 2.4 1 1 0 1 1 1 0 Mediator complex protein Synaptobrevin PF00957.16 EPX73003.1 - 0.77 9.3 5.1 1.4 8.6 0.1 3.1 3 0 0 3 3 3 0 Synaptobrevin Ribosomal_L3 PF00297.17 EPX73003.1 - 1.3 8.3 3.9 5.6 6.2 2.7 1.9 1 1 0 1 1 1 0 Ribosomal protein L3 DUF947 PF06102.7 EPX73004.1 - 1.2e-49 168.3 27.3 1.2e-49 168.3 19.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF947) SecE PF00584.15 EPX73004.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Pkinase PF00069.20 EPX73005.1 - 6.9e-49 166.3 0.1 4.5e-48 163.6 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73005.1 - 2.2e-19 69.5 0.0 3.3e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX73005.1 - 0.00053 19.7 0.1 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPX73005.1 - 0.017 14.4 0.0 0.037 13.3 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Sec20 PF03908.8 EPX73006.1 - 0.11 12.2 0.2 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Sec20 eIF-3c_N PF05470.7 EPX73007.1 - 2.6e-216 719.3 9.9 5.5e-172 572.9 2.8 4.1 2 2 2 4 4 4 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EPX73007.1 - 2.2e-12 47.2 0.4 8.7e-12 45.2 0.0 2.3 2 0 0 2 2 2 1 PCI domain Profilin PF00235.14 EPX73008.1 - 1.2e-39 135.1 0.0 1.3e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Profilin Proteasome PF00227.21 EPX73009.1 - 1.2e-45 155.1 0.2 1.5e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pribosyltran_N PF13793.1 EPX73010.1 - 2.4e-42 143.3 0.1 6.5e-41 138.7 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EPX73010.1 - 2.9e-35 121.6 0.1 2.5e-29 102.3 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EPX73010.1 - 0.00014 21.6 0.1 0.019 14.7 0.1 2.8 3 0 0 3 3 3 1 Phosphoribosyl transferase domain LRR_4 PF12799.2 EPX73011.1 - 2e-38 129.3 43.7 5.6e-09 35.4 0.5 7.2 3 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPX73011.1 - 5.7e-22 77.2 40.8 1.2e-06 28.1 2.3 6.2 2 1 4 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 EPX73011.1 - 3.3e-13 47.6 42.2 0.047 13.7 0.2 11.9 11 2 1 12 12 12 6 Leucine Rich Repeat LRR_9 PF14580.1 EPX73011.1 - 1.1e-12 47.8 16.7 6.4e-06 25.8 3.7 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.1 EPX73011.1 - 1.1e-08 34.2 36.5 0.8 9.9 0.4 10.3 5 3 3 8 8 8 4 Leucine Rich repeat LRR_7 PF13504.1 EPX73011.1 - 5.7e-08 31.7 34.3 0.22 11.8 0.0 10.5 10 0 0 10 10 10 3 Leucine rich repeat DUF2322 PF10084.4 EPX73011.1 - 0.00029 20.5 1.0 20 4.9 0.0 4.5 3 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2322) FNIP PF05725.7 EPX73011.1 - 0.3 11.0 0.2 0.3 11.0 0.2 4.4 5 1 0 5 5 5 0 FNIP Repeat ketoacyl-synt PF00109.21 EPX73012.1 - 3e-20 72.7 0.0 6.5e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EPX73012.1 - 4.9e-19 69.0 0.0 4.4e-18 65.9 0.0 2.4 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EPX73012.1 - 5.4e-17 61.6 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EPX73012.1 - 2.9e-08 33.5 0.0 6.7e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EPX73012.1 - 8e-06 25.8 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPX73012.1 - 0.0025 17.4 0.0 0.006 16.2 0.0 1.6 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EPX73012.1 - 0.026 14.6 0.2 2.2 8.3 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PP-binding PF00550.20 EPX73012.1 - 0.051 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site DUF3597 PF12200.3 EPX73012.1 - 0.067 13.5 0.6 0.22 11.9 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DUF676 PF05057.9 EPX73013.1 - 1.1e-57 194.8 0.0 1.7e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EPX73013.1 - 2.4e-05 24.1 0.1 4.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EPX73013.1 - 0.021 14.4 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EPX73013.1 - 0.027 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein cwf21 PF08312.7 EPX73014.1 - 1.2e-10 41.0 20.0 9e-08 31.8 13.8 2.8 1 1 0 1 1 1 1 cwf21 domain HSP70 PF00012.15 EPX73014.1 - 2.6 5.8 6.4 3.2 5.5 4.5 1.2 1 0 0 1 1 1 0 Hsp70 protein tRNA-synt_1 PF00133.17 EPX73015.1 - 1.6e-154 515.2 0.0 1.6e-153 511.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EPX73015.1 - 3.1e-18 65.6 6.1 3.6e-09 35.7 0.2 3.4 2 2 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EPX73015.1 - 6e-16 58.5 0.1 2e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 EPX73015.1 - 3.9e-06 26.3 0.0 0.0067 15.7 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EPX73015.1 - 2.2e-05 23.7 0.0 0.16 11.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EPX73015.1 - 0.00021 20.2 0.0 0.0019 17.0 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 EPX73015.1 - 0.0012 18.0 0.0 0.037 13.1 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Bac_export_1 PF01311.15 EPX73015.1 - 0.26 10.5 0.4 2.1 7.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial export proteins, family 1 DAGK_cat PF00781.19 EPX73016.1 - 8.7e-26 89.8 0.0 1.4e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF1975 PF09318.5 EPX73016.1 - 0.16 11.5 0.3 0.56 9.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1975) Abhydrolase_3 PF07859.8 EPX73017.1 - 8.5e-29 100.6 0.0 2.2e-19 69.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EPX73017.1 - 1.4e-11 43.6 0.1 7.3e-11 41.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EPX73017.1 - 0.00051 20.0 0.0 0.00085 19.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPX73017.1 - 0.087 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Myosin_head PF00063.16 EPX73018.1 - 2.3e-239 796.0 2.2 2.3e-239 796.0 1.5 2.3 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.14 EPX73018.1 - 1.8e-06 27.5 0.6 7.4e-06 25.5 0.1 2.3 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain ADIP PF11559.3 EPX73018.1 - 0.0031 17.4 9.1 0.0031 17.4 6.3 13.0 8 5 3 12 12 12 2 Afadin- and alpha -actinin-Binding AAA_19 PF13245.1 EPX73018.1 - 0.0096 15.6 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EPX73018.1 - 0.063 13.4 0.0 0.063 13.4 0.0 4.8 3 1 0 4 4 4 0 AAA domain Peptidase_S8 PF00082.17 EPX73019.1 - 9.1e-57 192.3 11.6 1.5e-56 191.6 8.0 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EPX73019.1 - 5.7e-13 49.2 0.7 1.3e-12 48.0 0.5 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 PP2C PF00481.16 EPX73020.1 - 3.5e-42 144.5 0.0 1.4e-40 139.2 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EPX73020.1 - 0.017 14.7 0.1 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) UPF0047 PF01894.12 EPX73021.1 - 2.4e-42 143.4 0.0 2.9e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Alpha-amylase PF00128.19 EPX73022.1 - 5.7e-57 193.4 0.0 7.5e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EPX73022.1 - 3.7e-15 55.7 0.0 4.3e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) WD40 PF00400.27 EPX73023.1 - 5.6e-48 159.1 10.1 1.6e-10 40.4 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EPX73023.1 - 3.5e-05 23.6 0.0 0.005 16.5 0.1 2.4 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EPX73023.1 - 0.00049 18.0 0.1 0.00091 17.1 0.1 1.4 1 0 0 1 1 1 1 IKI3 family Apc4_WD40 PF12894.2 EPX73023.1 - 0.0013 18.1 0.0 0.0045 16.4 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.1 EPX73023.1 - 0.13 12.5 3.2 69 3.9 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain DUF1620 PF07774.8 EPX73024.1 - 1.2e-64 217.5 1.0 2.2e-64 216.6 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EPX73024.1 - 0.021 14.3 0.0 0.27 10.6 0.0 2.6 3 0 0 3 3 3 0 PQQ-like domain Glyoxal_oxid_N PF07250.6 EPX73024.1 - 0.1 11.6 0.6 2.6 7.0 0.0 2.5 3 0 0 3 3 3 0 Glyoxal oxidase N-terminus DUF684 PF05075.9 EPX73025.1 - 0.1 11.1 0.6 0.14 10.7 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF684) CAF1C_H4-bd PF12265.3 EPX73026.1 - 1.5e-19 69.6 0.0 3.4e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 EPX73026.1 - 1.8e-11 43.4 8.4 0.00061 19.5 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat NHL PF01436.16 EPX73026.1 - 0.054 13.4 0.9 3.5 7.7 0.1 3.0 3 0 0 3 3 3 0 NHL repeat DUF2611 PF11022.3 EPX73027.1 - 5e-15 55.3 0.0 5.5e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) DUF1183 PF06682.7 EPX73028.1 - 2.7e-07 30.4 0.1 3.9e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Tetraspannin PF00335.15 EPX73028.1 - 0.029 13.6 1.0 0.44 9.7 0.4 2.1 2 0 0 2 2 2 0 Tetraspanin family Peptidase_C78 PF07910.8 EPX73029.1 - 1.4e-39 135.4 0.4 1.8e-39 135.1 0.3 1.1 1 0 0 1 1 1 1 Peptidase family C78 Guanylate_cyc_2 PF09778.4 EPX73029.1 - 0.094 11.8 1.6 0.28 10.3 0.1 2.3 1 1 1 2 2 2 0 Guanylylate cyclase DUF1649 PF07855.7 EPX73030.1 - 4.3e-23 81.7 0.0 5e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) JmjC PF02373.17 EPX73031.1 - 6.1e-20 71.5 1.4 1.5e-19 70.2 1.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EPX73031.1 - 6.8e-12 45.4 2.9 3.2e-11 43.2 2.0 2.0 1 1 0 1 1 1 1 Cupin-like domain GPI PF06560.6 EPX73031.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Avl9 PF09794.4 EPX73033.1 - 5.3e-119 397.0 0.3 7.1e-119 396.6 0.2 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 EPX73033.1 - 1.8e-08 34.0 0.6 0.0041 16.4 0.0 3.1 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.7 EPX73033.1 - 1.4e-05 25.1 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2207 PF09972.4 EPX73034.1 - 0.011 14.3 1.4 0.012 14.2 1.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF373 PF04123.8 EPX73034.1 - 0.053 12.5 1.0 0.065 12.2 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2077 PF09850.4 EPX73034.1 - 0.56 9.5 0.0 0.56 9.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) CcmH PF03918.9 EPX73034.1 - 6.3 5.7 6.0 0.54 9.2 0.2 1.9 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF202 PF02656.10 EPX73034.1 - 8.2 6.7 7.9 22 5.3 5.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) G-alpha PF00503.15 EPX73035.1 - 1.6e-105 353.0 7.9 1.9e-105 352.7 5.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EPX73035.1 - 2.1e-14 53.1 1.0 2.1e-09 36.8 0.1 2.9 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPX73035.1 - 0.00042 19.5 4.7 0.047 12.8 0.5 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EPX73035.1 - 0.021 14.3 0.1 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EPX73035.1 - 0.025 14.0 0.1 7.4 5.9 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain CPT PF07931.7 EPX73035.1 - 0.051 13.2 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein FtsK_SpoIIIE PF01580.13 EPX73035.1 - 0.07 12.5 0.1 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mit_KHE1 PF10173.4 EPX73036.1 - 2.9e-46 157.6 0.9 3.8e-46 157.3 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related SWIRM PF04433.12 EPX73037.1 - 9.9e-34 115.3 0.0 2.1e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EPX73037.1 - 5.3e-09 35.9 0.1 1.1e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPX73037.1 - 4.5e-08 33.0 0.1 1.9e-07 31.0 0.1 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EPX73037.1 - 0.011 15.2 8.8 0.02 14.3 6.1 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type Zn_ribbon_2 PF12674.2 EPX73037.1 - 0.044 14.1 0.7 0.044 14.1 0.5 1.9 2 0 0 2 2 2 0 Putative zinc ribbon domain DUF164 PF02591.10 EPX73037.1 - 0.051 13.3 1.1 0.1 12.4 0.8 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain SKN1 PF03935.10 EPX73038.1 - 5.3e-229 760.5 3.5 6.2e-229 760.2 2.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Beta_elim_lyase PF01212.16 EPX73039.1 - 3.6e-79 265.9 0.0 5.1e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EPX73039.1 - 0.00087 17.6 0.0 0.0013 17.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPX73039.1 - 0.003 16.5 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EPX73039.1 - 0.024 13.6 0.0 0.045 12.7 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EPX73039.1 - 0.063 12.0 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V WD40 PF00400.27 EPX73040.1 - 7.5e-19 66.8 3.9 0.00023 20.9 0.3 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EPX73040.1 - 0.0049 16.5 0.0 0.037 13.7 0.0 2.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Adaptin_N PF01602.15 EPX73041.1 - 1e-114 383.7 6.6 1.3e-114 383.4 4.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EPX73041.1 - 2.6e-14 53.2 0.1 1.4e-06 28.4 0.2 4.4 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.17 EPX73041.1 - 5.8e-09 35.2 4.7 0.34 11.1 0.0 6.5 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EPX73041.1 - 0.00023 21.5 6.3 0.77 10.3 0.2 5.6 8 0 0 8 8 8 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EPX73041.1 - 0.0037 17.1 0.2 1.8 8.6 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion CDT1 PF08839.6 EPX73041.1 - 0.018 14.9 0.3 0.13 12.1 0.1 2.5 3 0 0 3 3 3 0 DNA replication factor CDT1 like Ribosomal_S14 PF00253.16 EPX73042.1 - 2.7e-20 71.4 3.1 1.6e-19 68.9 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e WD40 PF00400.27 EPX73043.1 - 7.1e-15 54.2 9.2 5.4e-08 32.4 0.7 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EPX73043.1 - 4e-05 23.4 0.2 0.073 12.7 0.0 3.1 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A NPR2 PF06218.6 EPX73045.1 - 2.5e-138 461.3 12.1 3.2e-136 454.4 8.4 2.1 1 1 0 1 1 1 1 Nitrogen permease regulator 2 NPR3 PF03666.8 EPX73045.1 - 0.0023 16.5 3.1 0.71 8.3 0.0 3.0 2 1 1 3 3 3 3 Nitrogen Permease regulator of amino acid transport activity 3 DDE_1 PF03184.14 EPX73046.1 - 4.2e-58 196.0 2.8 5.4e-58 195.6 1.1 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EPX73046.1 - 4.5e-15 55.2 0.2 1.5e-14 53.5 0.1 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PHF5 PF03660.9 EPX73047.1 - 4.1e-49 165.1 12.1 4.7e-49 164.9 8.4 1.0 1 0 0 1 1 1 1 PHF5-like protein Fer4_8 PF13183.1 EPX73047.1 - 1.2 9.1 16.7 0.87 9.6 0.3 2.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain DZR PF12773.2 EPX73047.1 - 5.7 6.8 17.5 89 3.0 12.2 2.5 1 1 0 1 1 1 0 Double zinc ribbon PolC_DP2 PF03833.8 EPX73047.1 - 8.4 3.9 7.9 8.8 3.8 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Sec7 PF01369.15 EPX73048.1 - 1.1e-36 126.2 1.0 2.2e-36 125.2 0.7 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 EPX73048.1 - 0.00017 21.7 0.1 0.00078 19.6 0.0 2.2 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EPX73048.1 - 0.00033 20.7 0.1 0.0015 18.6 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EPX73049.1 - 9.4e-06 25.7 0.7 3.5e-05 23.9 0.2 2.3 2 1 0 2 2 2 1 PH domain Myotub-related PF06602.9 EPX73050.1 - 2.1e-139 464.1 1.2 2.7e-139 463.8 0.8 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 EPX73050.1 - 0.00015 21.1 0.1 0.0003 20.1 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EPX73050.1 - 0.00059 19.4 0.1 0.0013 18.2 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EPX73050.1 - 0.0034 17.6 0.0 0.0074 16.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family p450 PF00067.17 EPX73051.1 - 8.3e-55 186.1 0.0 1e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-RING_UBOX PF13445.1 EPX73051.1 - 0.053 13.2 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger ComX PF05952.7 EPX73051.1 - 0.1 12.1 0.0 0.31 10.5 0.0 1.8 1 0 0 1 1 1 0 Bacillus competence pheromone ComX VHS PF00790.14 EPX73052.1 - 6.2e-38 129.6 0.1 1.3e-37 128.5 0.1 1.5 1 0 0 1 1 1 1 VHS domain UIM PF02809.15 EPX73052.1 - 2.4e-08 32.8 8.8 0.00037 19.8 0.1 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif ENTH PF01417.15 EPX73052.1 - 0.0034 17.2 0.0 0.0088 15.9 0.0 1.7 1 0 0 1 1 1 1 ENTH domain adh_short PF00106.20 EPX73053.1 - 4.9e-11 42.8 0.0 8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPX73053.1 - 4.2e-06 26.5 0.0 6.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPX73053.1 - 0.0012 18.8 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPX73053.1 - 0.032 13.1 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EPX73053.1 - 0.039 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPX73053.1 - 0.13 11.5 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Brix PF04427.13 EPX73054.1 - 1.9e-45 154.9 0.0 2.5e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF2945 PF11160.3 EPX73055.1 - 1.3e-08 34.5 0.3 9.3e-07 28.5 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2945) COXG PF06240.8 EPX73055.1 - 0.084 12.5 0.1 0.091 12.4 0.1 1.0 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) DUF2551 PF10826.3 EPX73055.1 - 0.12 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) Bac_surface_Ag PF01103.18 EPX73056.1 - 8.4e-52 176.6 0.1 1.1e-51 176.2 0.0 1.1 1 0 0 1 1 1 1 Surface antigen Med27 PF11571.3 EPX73057.1 - 9e-08 32.1 2.5 1.3e-07 31.6 0.1 2.3 3 0 0 3 3 3 1 Mediator complex subunit 27 Syntaxin PF00804.20 EPX73057.1 - 0.13 12.4 3.4 0.081 13.0 0.7 1.8 2 0 0 2 2 2 0 Syntaxin MIF4G PF02854.14 EPX73058.1 - 1.1e-58 198.1 0.0 2.1e-58 197.1 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EPX73058.1 - 2e-14 53.1 0.1 1e-13 50.9 0.1 2.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Fibrinogen_BP PF08017.6 EPX73058.1 - 3.7e-06 25.3 39.0 8.2e-06 24.2 27.0 1.5 1 0 0 1 1 1 1 Fibrinogen binding protein ACPS PF01648.15 EPX73059.1 - 2.4e-10 40.2 0.0 4.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily TPR_11 PF13414.1 EPX73060.1 - 2.2e-36 123.3 14.0 2.6e-10 39.8 0.1 7.6 3 1 4 8 8 8 7 TPR repeat TPR_1 PF00515.23 EPX73060.1 - 2.4e-35 118.6 17.0 4.9e-08 32.2 0.1 9.9 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EPX73060.1 - 3.2e-35 117.2 16.8 2.2e-07 30.2 0.1 11.1 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_8 PF13181.1 EPX73060.1 - 3.4e-30 101.5 9.0 2.7e-05 23.6 0.0 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat Apc3 PF12895.2 EPX73060.1 - 9.7e-27 92.9 19.5 1.6e-18 66.5 0.9 6.0 3 1 6 9 9 9 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EPX73060.1 - 3.4e-24 84.5 2.5 4e-06 26.6 0.3 7.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EPX73060.1 - 9.8e-21 73.8 2.0 1.3e-05 25.4 0.1 6.2 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPX73060.1 - 6.1e-19 66.5 9.6 0.0019 18.2 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EPX73060.1 - 4.2e-16 57.9 0.0 0.11 13.2 0.0 8.2 6 2 4 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPX73060.1 - 1.1e-13 51.4 2.1 3.3e-05 24.4 0.0 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPX73060.1 - 8.4e-11 40.8 0.0 1.1 9.2 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EPX73060.1 - 1.6e-10 40.7 7.1 0.0086 16.4 0.0 7.5 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPX73060.1 - 0.00042 20.0 0.3 4.1 7.3 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EPX73060.1 - 0.017 15.0 0.0 22 5.1 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat ChAPs PF09295.5 EPX73060.1 - 0.019 13.7 0.0 0.26 10.0 0.0 2.5 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.13 EPX73060.1 - 0.019 14.8 0.3 7.5 6.5 0.0 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 EPX73060.1 - 0.019 15.5 6.5 0.52 11.0 0.0 4.8 5 0 0 5 5 4 0 Sel1 repeat PPTA PF01239.17 EPX73060.1 - 0.024 13.9 3.2 8.2 5.9 0.1 3.7 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat TPR_21 PF09976.4 EPX73060.1 - 0.11 12.4 0.7 0.38 10.6 0.0 2.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 EPX73060.1 - 0.12 12.2 2.0 15 5.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EPX73060.1 - 3.6 7.5 12.7 4.3 7.2 0.0 5.3 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat Acyltransferase PF01553.16 EPX73061.1 - 6e-32 109.8 0.0 8.1e-32 109.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Ribosomal_L13e PF01294.13 EPX73061.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L13e CK_II_beta PF01214.13 EPX73062.1 - 6.4e-79 263.7 0.0 8.7e-79 263.3 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RIC1 PF07064.8 EPX73063.1 - 1.1e-37 129.9 1.8 1.1e-37 129.9 1.3 1.9 3 0 0 3 3 3 1 RIC1 PQQ_3 PF13570.1 EPX73063.1 - 0.076 13.3 2.4 0.28 11.5 0.0 3.3 4 0 0 4 4 4 0 PQQ-like domain GRIP PF01465.15 EPX73064.1 - 8.5e-11 41.1 1.4 2.7e-10 39.5 1.0 2.0 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 EPX73064.1 - 0.00027 20.6 20.5 0.00027 20.6 14.2 6.2 2 2 2 4 4 4 1 IncA protein Reo_sigmaC PF04582.7 EPX73064.1 - 1.8 7.6 19.9 0.056 12.6 1.0 4.1 2 2 2 4 4 4 0 Reovirus sigma C capsid protein RRM_2 PF04059.7 EPX73065.1 - 7.9e-52 173.2 0.7 1.6e-51 172.2 0.5 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EPX73065.1 - 6.9e-16 57.6 0.0 7.7e-07 28.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX73065.1 - 2.7e-07 30.4 0.0 0.0065 16.4 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX73065.1 - 3.2e-07 30.0 0.1 0.006 16.4 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pterin_4a PF01329.14 EPX73066.1 - 8.1e-30 102.4 0.1 9e-30 102.2 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Cactin_mid PF10312.4 EPX73067.1 - 0.0053 16.0 0.1 0.0061 15.8 0.0 1.1 1 0 0 1 1 1 1 Conserved mid region of cactin LSM PF01423.17 EPX73068.1 - 5.8e-19 67.4 0.5 8.3e-19 66.9 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPX73068.1 - 0.0085 15.9 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.3 EPX73068.1 - 0.046 13.4 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) API5 PF05918.6 EPX73068.1 - 0.12 10.8 7.0 0.16 10.3 4.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ETF PF01012.16 EPX73069.1 - 4e-36 124.2 0.2 7.2e-36 123.3 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EPX73069.1 - 2.6e-32 110.2 0.1 5.3e-32 109.2 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Methyltransf_10 PF05971.7 EPX73070.1 - 1.7e-57 194.8 0.0 4.8e-57 193.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EPX73070.1 - 0.0002 21.3 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPX73070.1 - 0.0025 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EPX73070.1 - 0.0041 16.2 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 EPX73070.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EPX73070.1 - 0.13 11.6 0.0 0.6 9.4 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein 95 But2 PF09792.4 EPX73072.1 - 3.4e-41 140.3 0.9 3.4e-41 140.3 0.6 1.6 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain ApbA PF02558.11 EPX73072.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CAP_GLY PF01302.20 EPX73074.1 - 6.3e-21 73.8 0.2 1.1e-20 73.0 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain TPR_1 PF00515.23 EPX73075.1 - 3.4e-35 118.2 7.6 7.7e-06 25.3 0.1 10.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 EPX73075.1 - 1.8e-33 114.0 19.7 8.2e-07 28.5 0.0 10.5 8 3 2 11 11 11 6 TPR repeat TPR_2 PF07719.12 EPX73075.1 - 1.3e-32 109.0 15.8 2e-05 24.1 0.1 12.3 13 0 0 13 13 12 7 Tetratricopeptide repeat TPR_12 PF13424.1 EPX73075.1 - 2.2e-28 97.9 17.7 9e-06 25.5 0.2 9.2 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 EPX73075.1 - 5.3e-25 85.2 12.1 0.00094 18.8 0.0 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 EPX73075.1 - 2.4e-23 82.2 6.0 0.00015 22.0 0.0 8.2 6 3 2 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EPX73075.1 - 1e-19 69.1 7.6 0.12 13.0 0.0 10.6 7 4 4 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPX73075.1 - 2.8e-19 69.2 5.4 0.0027 18.3 0.0 8.9 8 2 2 11 11 10 5 Tetratricopeptide repeat TPR_6 PF13174.1 EPX73075.1 - 7.9e-18 63.6 12.7 0.0031 17.8 0.3 10.3 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 EPX73075.1 - 5.2e-13 47.7 12.6 0.0042 16.7 0.1 9.2 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPX73075.1 - 7.9e-10 38.1 13.3 1.7 9.0 0.0 11.6 13 0 0 13 13 13 1 Tetratricopeptide repeat Apc3 PF12895.2 EPX73075.1 - 8e-09 35.5 5.0 0.037 14.1 0.0 5.4 5 2 1 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EPX73075.1 - 8.2e-07 28.7 20.4 2.7 8.0 0.1 8.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EPX73075.1 - 1.8e-06 27.7 1.4 4 7.3 0.0 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_3 PF07720.7 EPX73075.1 - 1.9 8.4 9.2 15 5.4 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1774 PF08611.5 EPX73076.1 - 8.4e-24 83.5 5.8 8.4e-24 83.5 4.0 3.0 2 1 1 3 3 3 1 Fungal protein of unknown function (DUF1774) DUF3043 PF11241.3 EPX73076.1 - 8.7 5.9 9.4 0.29 10.7 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3043) TPR_11 PF13414.1 EPX73077.1 - 4.9e-17 61.3 11.9 4.2e-07 29.5 1.0 4.4 4 1 1 5 5 5 4 TPR repeat TPR_16 PF13432.1 EPX73077.1 - 2.1e-13 50.5 0.4 2.6e-05 24.7 0.6 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPX73077.1 - 1.6e-12 46.3 15.1 0.002 17.9 0.2 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPX73077.1 - 6.4e-08 32.8 7.0 0.0047 17.2 0.8 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPX73077.1 - 1e-07 31.8 0.6 0.12 13.0 0.1 5.7 5 1 1 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EPX73077.1 - 2e-07 31.0 12.9 0.017 15.2 0.2 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EPX73077.1 - 9.7e-07 28.1 16.4 0.027 14.0 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPX73077.1 - 2.3e-05 24.2 9.0 0.2 11.9 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPX73077.1 - 0.00017 21.1 9.3 0.27 11.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPX73077.1 - 0.0019 18.0 7.1 0.083 12.7 0.0 4.6 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPX73077.1 - 0.0028 16.7 1.9 0.45 9.5 0.8 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF1041 PF06292.12 EPX73077.1 - 0.0052 16.9 0.1 0.021 14.9 0.1 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) ATP-synt_ab PF00006.20 EPX73078.1 - 9e-59 198.5 0.0 1.2e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPX73078.1 - 6.5e-17 62.0 0.1 1.2e-16 61.1 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPX73078.1 - 1.2e-09 38.2 0.4 3.2e-09 36.8 0.1 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Glyco_transf_34 PF05637.7 EPX73079.1 - 2.5e-71 239.9 0.7 3e-71 239.7 0.5 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family eIF-3_zeta PF05091.7 EPX73080.1 - 3.4e-187 623.1 0.0 3.9e-187 622.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ParA PF10609.4 EPX73081.1 - 2e-37 126.8 0.1 4.7e-37 125.7 0.1 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EPX73081.1 - 1.6e-15 57.0 0.0 2.6e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EPX73081.1 - 1.3e-06 27.7 0.6 4.9e-05 22.5 0.1 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 EPX73081.1 - 1.1e-05 24.6 0.0 2e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 EPX73081.1 - 0.00014 21.8 0.0 0.0012 18.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.1 EPX73081.1 - 0.00019 21.1 0.0 0.0033 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain SIS_2 PF13580.1 EPX73081.1 - 0.0028 17.3 0.0 0.54 9.9 0.0 2.3 2 0 0 2 2 2 1 SIS domain AAA_25 PF13481.1 EPX73081.1 - 0.003 17.0 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPX73081.1 - 0.0042 16.2 0.1 0.0081 15.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Fer4_NifH PF00142.13 EPX73081.1 - 0.013 14.6 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EPX73081.1 - 0.036 13.5 0.0 0.86 9.0 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 EPX73081.1 - 0.041 12.7 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 EPX73081.1 - 0.11 12.4 0.1 0.37 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EPX73081.1 - 0.13 12.0 0.1 4.6 7.0 0.0 2.7 2 1 0 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 EPX73081.1 - 0.13 11.8 0.2 0.34 10.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EPX73081.1 - 0.13 13.0 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNase_T PF00929.19 EPX73082.1 - 8.2e-26 91.2 0.0 1.5e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 Exonuclease SR-25 PF10500.4 EPX73082.1 - 0.0044 16.5 19.4 0.0044 16.5 13.4 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 EPX73082.1 - 0.58 8.1 7.5 0.1 10.6 2.4 1.7 2 0 0 2 2 2 0 CDC45-like protein VWA_2 PF13519.1 EPX73083.1 - 1.4e-11 44.8 0.0 2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EPX73083.1 - 1.5e-08 34.4 0.0 2.6e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Ssl1-like VWA PF00092.23 EPX73083.1 - 0.00052 19.7 0.0 0.00067 19.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EPX73083.1 - 0.0062 16.0 2.0 0.019 14.4 1.4 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif XPC-binding PF09280.6 EPX73083.1 - 0.016 14.6 0.0 0.039 13.3 0.0 1.7 1 0 0 1 1 1 0 XPC-binding domain Glycos_transf_1 PF00534.15 EPX73083.1 - 0.095 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Helicase_C PF00271.26 EPX73084.1 - 4.4e-10 39.2 0.0 1.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.3 EPX73084.1 - 1.8e-08 33.6 0.5 7.2e-07 28.5 0.0 2.6 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal DEAD PF00270.24 EPX73084.1 - 0.024 14.1 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase MOZ_SAS PF01853.13 EPX73085.1 - 8.6e-89 295.7 2.8 1.2e-88 295.2 1.9 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EPX73085.1 - 5.4e-20 70.8 1.6 1.4e-19 69.4 1.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EPX73085.1 - 0.031 13.9 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Acetyltransf_1 PF00583.19 EPX73085.1 - 0.084 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PH PF00169.24 EPX73086.1 - 2e-05 24.6 0.7 5.6e-05 23.2 0.0 2.1 2 1 0 2 2 2 1 PH domain DUF2659 PF10858.3 EPX73086.1 - 0.023 14.1 0.4 0.041 13.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) PV_NSP1 PF12433.3 EPX73086.1 - 0.058 13.4 0.1 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein 1 Zds_C PF08632.5 EPX73087.1 - 5.2e-31 105.8 0.5 9.2e-31 105.0 0.3 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term HECT PF00632.20 EPX73088.1 - 5e-79 265.7 0.0 1.2e-78 264.5 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FecCD PF01032.13 EPX73089.1 - 0.0034 16.2 0.3 0.0047 15.7 0.2 1.1 1 0 0 1 1 1 1 FecCD transport family WD40 PF00400.27 EPX73090.1 - 3.2e-19 68.0 11.9 1.8e-05 24.4 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EPX73090.1 - 7.6e-05 22.5 0.0 0.013 15.1 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EPX73090.1 - 0.026 14.1 0.0 0.94 9.2 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EPX73090.1 - 0.033 12.0 0.0 0.35 8.6 0.0 1.9 1 1 1 2 2 2 0 IKI3 family TTL PF03133.10 EPX73091.1 - 9.8e-60 201.9 0.5 1.3e-59 201.5 0.3 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 EPX73091.1 - 0.00021 21.0 0.0 0.017 14.8 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EPX73091.1 - 0.0006 18.6 0.0 0.0024 16.7 0.0 2.0 2 1 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 EPX73091.1 - 0.0076 16.1 0.0 3 7.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPX73091.1 - 0.018 13.8 0.0 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EPX73091.1 - 0.058 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Peptidase_M24 PF00557.19 EPX73092.1 - 3.8e-47 160.5 0.0 7.1e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EPX73092.1 - 7.5e-23 80.3 0.0 1.6e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Sdh5 PF03937.11 EPX73093.1 - 6.9e-23 80.1 0.5 9.1e-23 79.7 0.3 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase F-actin_cap_A PF01267.12 EPX73094.1 - 1.5e-62 211.0 3.9 1.7e-62 210.9 2.7 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Mito_carr PF00153.22 EPX73095.1 - 4.3e-50 167.3 3.8 9.7e-19 66.8 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Cellulase PF00150.13 EPX73097.1 - 2.4e-09 36.7 0.4 2.4e-09 36.7 0.2 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Rad4 PF03835.10 EPX73098.1 - 3.6e-30 104.2 0.0 7.4e-30 103.2 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EPX73098.1 - 1.3e-23 82.4 0.0 2.4e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EPX73098.1 - 1.8e-20 72.2 0.4 1.7e-19 69.0 0.1 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EPX73098.1 - 1.1e-13 51.3 0.1 3.8e-13 49.5 0.1 2.1 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EPX73098.1 - 0.0069 16.5 0.0 0.017 15.3 0.0 1.7 1 1 0 1 1 1 1 Transglutaminase-like superfamily Gag_spuma PF03276.9 EPX73098.1 - 0.029 12.7 0.0 0.043 12.1 0.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein CLTH PF10607.4 EPX73099.1 - 1.9e-34 118.4 1.8 2.3e-34 118.1 1.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EPX73099.1 - 0.0028 17.3 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 LisH RNase_H2_suC PF08615.6 EPX73101.1 - 1.7e-21 76.5 0.0 2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF1237 PF06824.6 EPX73102.1 - 2.8e-176 586.2 0.0 3.2e-176 586.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) PPR_2 PF13041.1 EPX73103.1 - 4.2e-38 129.0 16.1 1.6e-11 44.0 0.0 12.5 10 2 4 14 14 14 7 PPR repeat family PPR_3 PF13812.1 EPX73103.1 - 8.2e-29 97.4 6.4 0.00028 20.9 0.0 13.5 15 0 0 15 15 15 5 Pentatricopeptide repeat domain PPR PF01535.15 EPX73103.1 - 1.5e-22 77.9 18.1 0.0001 22.0 0.0 12.2 16 1 0 16 16 16 5 PPR repeat PPR_1 PF12854.2 EPX73103.1 - 4.8e-19 67.5 4.1 2.5e-06 26.8 0.0 8.6 11 0 0 11 11 11 4 PPR repeat RPM2 PF08579.6 EPX73103.1 - 0.0097 16.0 0.4 0.4 10.8 0.0 3.3 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) DDE_1 PF03184.14 EPX73104.1 - 2.2e-55 187.1 0.3 5.5e-55 185.8 0.2 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EPX73104.1 - 7.5e-17 60.9 1.8 2.8e-16 59.0 0.5 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain PNPOx_C PF10590.4 EPX73105.1 - 4.1e-17 61.3 1.6 1.1e-16 60.0 0.8 2.0 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EPX73105.1 - 3.3e-15 55.8 0.0 5.6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EPX73105.1 - 0.0027 17.9 0.0 0.0054 17.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Orn_Arg_deC_N PF02784.11 EPX73106.1 - 1.3e-73 247.3 0.0 1.8e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EPX73106.1 - 2.9e-36 123.7 0.2 6.5e-36 122.5 0.1 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Adenylsucc_synt PF00709.16 EPX73107.1 - 1.8e-165 550.7 0.0 2e-165 550.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase zf-H2C2_2 PF13465.1 EPX73108.1 - 3.3e-09 36.5 4.3 5.8e-06 26.3 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPX73108.1 - 9.5e-06 25.6 0.2 9.5e-06 25.6 0.1 4.4 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPX73108.1 - 8.4e-05 22.6 0.1 8.4e-05 22.6 0.1 3.1 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.2 EPX73108.1 - 0.025 14.7 0.1 5.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EPX73108.1 - 0.026 14.4 0.2 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.7 EPX73108.1 - 0.11 11.0 2.7 3.5 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF629) DUF3166 PF11365.3 EPX73108.1 - 0.2 12.1 1.7 4 7.9 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) zf-Di19 PF05605.7 EPX73108.1 - 0.22 11.6 3.5 14 5.9 0.3 2.8 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF3209 PF11483.3 EPX73110.1 - 0.011 16.0 0.9 0.013 15.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) PHA-1 PF06542.6 EPX73110.1 - 0.15 10.7 3.6 0.16 10.6 2.5 1.0 1 0 0 1 1 1 0 Regulator protein PHA-1 Mre11_DNA_bind PF04152.9 EPX73110.1 - 0.23 11.2 9.3 0.2 11.4 5.9 1.3 1 1 0 1 1 1 0 Mre11 DNA-binding presumed domain SPATIAL PF15256.1 EPX73110.1 - 0.35 10.8 6.1 0.38 10.8 4.2 1.0 1 0 0 1 1 1 0 SPATIAL DUF4569 PF15133.1 EPX73110.1 - 2.1 7.6 6.2 2.5 7.3 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Calc_CGRP_IAPP PF00214.14 EPX73110.1 - 6.4 6.8 6.0 5 7.1 3.2 1.4 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family Porin_3 PF01459.17 EPX73111.1 - 1.3e-57 195.1 3.3 1.5e-57 195.0 2.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF2408 PF10303.4 EPX73112.1 - 1.7e-61 206.1 12.3 2.6e-34 118.2 0.1 5.5 3 3 2 5 5 5 5 Protein of unknown function (DUF2408) FH2 PF02181.18 EPX73112.1 - 0.0068 15.3 0.5 0.02 13.7 0.1 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Laminin_II PF06009.7 EPX73112.1 - 0.11 12.2 3.1 2.9 7.6 0.1 4.0 3 1 1 4 4 4 0 Laminin Domain II FNIP_N PF14636.1 EPX73113.1 - 0.0036 17.7 0.1 0.0036 17.7 0.0 4.6 3 2 1 4 4 4 2 Folliculin-interacting protein N-terminus Tubulin_3 PF14881.1 EPX73114.1 - 3.5e-35 121.0 0.0 7.1e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EPX73114.1 - 2.8e-23 82.1 0.3 1e-22 80.3 0.0 2.0 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EPX73114.1 - 0.02 14.6 0.0 0.063 13.0 0.0 1.8 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain Cornichon PF03311.9 EPX73115.1 - 3.4e-45 153.2 11.5 3.8e-45 153.1 7.9 1.0 1 0 0 1 1 1 1 Cornichon protein GPDPase_memb PF10110.4 EPX73115.1 - 0.57 9.5 8.4 0.84 9.0 5.9 1.3 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF1673 PF07895.6 EPX73115.1 - 5.3 6.5 9.2 10 5.6 6.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) tRNA_bind PF01588.15 EPX73116.1 - 2.2e-26 91.5 0.1 5.7e-26 90.2 0.1 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EPX73116.1 - 0.00029 21.2 0.0 0.00029 21.2 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RR_TM4-6 PF06459.7 EPX73116.1 - 0.41 10.4 8.6 0.64 9.8 5.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 EPX73116.1 - 0.42 9.3 11.7 0.64 8.7 8.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDHD PF02862.12 EPX73116.1 - 1 9.1 4.9 1.9 8.2 3.4 1.4 1 0 0 1 1 1 0 DDHD domain RNA_polI_A34 PF08208.6 EPX73116.1 - 6.2 6.4 26.0 12 5.5 17.7 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Ribonuclease_P PF00825.13 EPX73117.1 - 0.00099 18.9 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease P HEAT_2 PF13646.1 EPX73118.1 - 2.8e-33 114.0 0.0 2.7e-12 46.7 0.0 4.1 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.11 EPX73118.1 - 3.3e-27 92.1 0.0 0.00014 21.9 0.0 8.0 9 0 0 9 9 9 5 PBS lyase HEAT-like repeat HEAT PF02985.17 EPX73118.1 - 2.4e-09 36.4 0.2 1.7 8.9 0.0 5.7 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EPX73118.1 - 3.9e-08 33.5 0.0 0.17 12.4 0.0 4.6 4 2 2 6 6 6 3 HEAT-like repeat RuvA_C PF07499.8 EPX73118.1 - 0.19 11.9 0.9 1.4 9.1 0.0 2.7 3 0 0 3 3 3 0 RuvA, C-terminal domain DHC_N1 PF08385.7 EPX73119.1 - 6.7e-107 358.2 29.1 6.7e-107 358.2 20.2 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EPX73119.1 - 7.2e-68 228.9 7.5 7.2e-68 228.9 5.2 4.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EPX73119.1 - 9.3e-52 175.8 0.3 3.6e-51 173.9 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 EPX73119.1 - 2.2e-25 89.0 0.0 1.6e-12 47.3 0.0 5.4 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) MT PF12777.2 EPX73119.1 - 2.5e-22 79.1 5.9 4.7e-22 78.1 4.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.10 EPX73119.1 - 3.5e-21 74.9 0.1 3.5e-21 74.9 0.0 1.6 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 EPX73119.1 - 9.1e-14 50.8 0.3 3.3e-13 49.0 0.2 2.0 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_22 PF13401.1 EPX73119.1 - 1e-11 45.0 0.9 0.0023 18.0 0.0 5.6 6 0 0 6 6 5 2 AAA domain AAA PF00004.24 EPX73119.1 - 8.6e-10 38.9 0.0 0.051 13.7 0.0 4.3 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPX73119.1 - 3.3e-07 30.4 0.0 0.21 11.5 0.0 4.6 4 0 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 EPX73119.1 - 1.7e-05 25.6 2.8 0.84 10.4 0.0 4.7 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.1 EPX73119.1 - 4.1e-05 23.4 0.0 1.8 8.4 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EPX73119.1 - 0.0001 21.9 0.0 0.95 9.2 0.1 3.4 3 0 0 3 3 3 1 Part of AAA domain RNA_helicase PF00910.17 EPX73119.1 - 0.00011 22.3 0.0 0.62 10.2 0.0 4.2 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.1 EPX73119.1 - 0.00074 19.8 0.0 2.2 8.5 0.0 4.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EPX73119.1 - 0.00091 18.6 0.0 0.13 11.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EPX73119.1 - 0.042 12.7 0.0 5.1 5.9 0.1 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 EPX73119.1 - 0.048 12.8 0.7 7.2 5.7 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF881 PF05949.7 EPX73119.1 - 0.048 13.1 0.5 0.11 11.9 0.1 1.8 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF881) AAA_28 PF13521.1 EPX73119.1 - 0.19 11.7 0.0 50 3.8 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.1 EPX73119.1 - 0.54 9.8 0.0 11 5.5 0.1 2.6 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EPX73119.1 - 0.73 9.2 0.0 9.9 5.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF1664 PF07889.7 EPX73119.1 - 3.2 7.5 13.4 0.16 11.7 0.9 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DEAD PF00270.24 EPX73120.1 - 1.1e-44 151.8 0.0 2.1e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EPX73120.1 - 1.4e-24 85.3 0.2 2.9e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EPX73120.1 - 7.6e-22 76.9 0.0 2.2e-21 75.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EPX73120.1 - 0.0018 18.2 0.0 0.006 16.5 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 EPX73120.1 - 0.0028 16.5 0.0 0.0059 15.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.1 EPX73120.1 - 0.067 12.9 0.2 0.81 9.4 0.0 2.7 3 0 0 3 3 3 0 Part of AAA domain PolyA_pol PF01743.15 EPX73121.1 - 8.3e-27 93.8 0.0 1.8e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EPX73121.1 - 3.3e-09 36.1 0.0 7.9e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EPX73121.1 - 0.0043 16.8 0.4 0.022 14.5 0.3 2.1 1 1 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Syja_N PF02383.13 EPX73122.1 - 7.5e-86 287.7 0.0 4e-85 285.3 0.0 2.0 2 0 0 2 2 2 1 SacI homology domain RRM_6 PF14259.1 EPX73123.1 - 9.1e-16 57.5 0.4 0.0076 16.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX73123.1 - 3.6e-14 52.1 0.3 3.9e-05 23.1 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX73123.1 - 5.7e-13 48.4 0.1 0.0024 17.6 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alg6_Alg8 PF03155.10 EPX73124.1 - 2.3e-161 537.7 44.1 3.1e-161 537.3 30.6 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family RhoGAP PF00620.22 EPX73125.1 - 4.7e-36 123.6 0.0 9.6e-36 122.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EPX73125.1 - 9.5e-25 86.4 41.8 3.5e-12 46.1 4.0 5.6 5 0 0 5 5 5 4 LIM domain Rubella_Capsid PF05750.6 EPX73125.1 - 0.077 12.3 2.7 0.17 11.2 1.8 1.5 1 1 0 1 1 1 0 Rubella capsid protein Nop14 PF04147.7 EPX73126.1 - 7e-226 752.0 27.2 8.6e-226 751.7 18.9 1.1 1 0 0 1 1 1 1 Nop14-like family Pyr_redox_2 PF07992.9 EPX73127.1 - 4.3e-27 95.2 0.1 5.1e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPX73127.1 - 6.7e-17 61.6 0.2 1.5e-14 54.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPX73127.1 - 6.5e-08 32.8 0.1 1.7e-05 24.9 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPX73127.1 - 4.7e-06 25.8 0.2 0.00026 20.1 0.0 2.6 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 EPX73127.1 - 1.6e-05 23.9 0.9 0.28 10.0 0.0 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EPX73127.1 - 0.0001 22.5 0.0 0.016 15.4 0.0 3.0 2 1 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.17 EPX73127.1 - 0.00018 20.5 0.8 0.061 12.1 0.1 3.5 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EPX73127.1 - 0.00028 20.0 0.1 0.11 11.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EPX73127.1 - 0.00065 19.6 0.6 0.056 13.4 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EPX73127.1 - 0.00069 19.7 0.1 0.37 10.8 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EPX73127.1 - 0.0027 16.6 2.4 0.022 13.6 0.4 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EPX73127.1 - 0.0035 17.1 0.1 1.1 9.0 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EPX73127.1 - 0.023 13.1 0.6 0.079 11.4 0.3 2.0 2 1 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 EPX73127.1 - 0.027 13.1 0.2 0.14 10.7 0.1 2.2 3 0 0 3 3 3 0 Tryptophan halogenase K_oxygenase PF13434.1 EPX73127.1 - 0.028 13.3 0.4 0.69 8.7 0.0 3.0 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 EPX73127.1 - 0.059 12.4 0.3 0.61 9.1 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3Beta_HSD PF01073.14 EPX73128.1 - 2.8e-67 226.3 0.0 3.3e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPX73128.1 - 1.1e-30 106.7 0.0 1.5e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPX73128.1 - 3.4e-15 55.7 0.0 4.4e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EPX73128.1 - 8e-13 47.8 0.0 3.1e-11 42.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EPX73128.1 - 2.5e-10 40.6 0.0 3.9e-10 40.0 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPX73128.1 - 6.3e-08 31.8 0.0 1.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPX73128.1 - 7.1e-05 22.7 0.0 0.00018 21.4 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPX73128.1 - 0.00029 20.5 0.0 0.0012 18.5 0.0 1.9 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EPX73128.1 - 0.0068 15.4 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EPX73128.1 - 0.034 14.1 0.0 0.061 13.3 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain DUF758 PF05527.6 EPX73128.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF758) Metallophos PF00149.23 EPX73129.1 - 2.5e-38 131.5 0.1 3.7e-38 130.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EPX73129.1 - 1.8e-27 94.7 7.5 5.6e-20 70.7 1.3 2.5 1 1 1 2 2 2 2 TPR repeat PPP5 PF08321.7 EPX73129.1 - 6.6e-26 90.1 0.3 2e-25 88.6 0.1 1.9 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.23 EPX73129.1 - 2.6e-18 64.7 7.2 5.4e-05 22.6 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPX73129.1 - 5.3e-17 60.3 4.6 0.00012 21.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPX73129.1 - 6.1e-09 35.3 3.5 0.0038 17.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPX73129.1 - 2.1e-07 30.9 0.1 0.0082 16.6 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPX73129.1 - 2.3e-07 31.3 1.6 0.00033 21.2 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPX73129.1 - 3.5e-06 26.4 6.3 0.018 14.8 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPX73129.1 - 1.6e-05 25.1 1.7 0.056 13.7 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPX73129.1 - 4.6e-05 23.2 3.0 0.0027 17.6 0.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 EPX73129.1 - 0.0026 16.8 0.8 0.6 9.1 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat DUF3808 PF10300.4 EPX73129.1 - 0.01 14.4 1.1 0.015 13.9 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) TPR_6 PF13174.1 EPX73129.1 - 0.01 16.2 1.4 1.6 9.3 0.2 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EPX73129.1 - 0.019 14.7 0.0 0.28 11.0 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.7 EPX73129.1 - 0.056 14.0 0.2 2.6 8.7 0.1 2.7 2 0 0 2 2 2 0 Sel1 repeat TPR_7 PF13176.1 EPX73129.1 - 0.082 12.7 0.1 10 6.1 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Alk_phosphatase PF00245.15 EPX73130.1 - 2.3e-100 336.2 0.0 2.7e-100 336.0 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EPX73130.1 - 0.0015 17.9 0.0 0.005 16.2 0.0 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily PX PF00787.19 EPX73131.1 - 9.6e-19 67.2 0.8 2.8e-18 65.7 0.6 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EPX73131.1 - 0.0018 17.5 8.8 0.018 14.2 1.5 2.5 2 0 0 2 2 2 2 Vps5 C terminal like Tropomyosin_1 PF12718.2 EPX73131.1 - 0.0081 16.0 4.2 0.014 15.2 1.9 2.0 1 1 0 1 1 1 1 Tropomyosin like LON PF02190.11 EPX73132.1 - 2.4e-17 63.2 0.0 3.8e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EPX73132.1 - 4.9e-11 42.4 22.4 9.4e-09 35.1 6.4 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX73132.1 - 5.6e-11 41.9 12.9 1.8e-08 33.9 4.0 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPX73132.1 - 1.8e-10 40.4 19.7 1.7e-05 24.5 3.1 3.7 3 0 0 3 3 3 3 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EPX73132.1 - 3.3e-10 39.4 18.6 4.6e-08 32.5 6.0 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPX73132.1 - 3.4e-10 39.5 16.9 7.2e-08 32.1 6.5 3.0 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 EPX73132.1 - 1.4e-08 34.3 8.0 1.4e-08 34.3 5.6 2.9 3 0 0 3 3 3 2 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPX73132.1 - 1.3e-06 27.9 8.2 0.00057 19.5 1.4 3.1 2 1 0 2 2 2 2 RING-type zinc-finger U-box PF04564.10 EPX73132.1 - 0.0025 17.7 0.4 0.056 13.4 0.0 3.2 4 0 0 4 4 4 1 U-box domain zf-rbx1 PF12678.2 EPX73132.1 - 0.023 14.8 2.4 0.072 13.2 1.6 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EPX73132.1 - 0.053 13.1 14.3 0.25 10.9 4.9 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain SSFA2_C PF14723.1 EPX73132.1 - 0.4 10.4 2.8 16 5.1 0.9 2.4 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Prok-RING_4 PF14447.1 EPX73132.1 - 1.8 8.1 10.9 0.5 9.9 0.5 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Lyase_1 PF00206.15 EPX73133.1 - 1.5e-23 83.4 0.0 2.8e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EPX73133.1 - 1.8e-14 53.4 0.0 5e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus AsiA PF09010.5 EPX73133.1 - 0.016 15.0 0.0 0.051 13.4 0.0 1.8 2 0 0 2 2 2 0 Anti-Sigma Factor A Med7 PF05983.6 EPX73134.1 - 1.3e-44 151.8 17.7 3.5e-31 108.1 7.0 2.3 2 1 0 2 2 2 2 MED7 protein DUF4407 PF14362.1 EPX73134.1 - 0.94 8.3 8.0 1.7 7.4 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF2201_N PF13203.1 EPX73134.1 - 4 6.5 8.5 0.11 11.7 1.4 1.6 2 0 0 2 2 2 0 Putative metallopeptidase domain RINGv PF12906.2 EPX73135.1 - 1e-15 57.4 13.8 1.8e-15 56.6 9.5 1.4 1 0 0 1 1 1 1 RING-variant domain ABC_tran PF00005.22 EPX73136.1 - 2.3e-33 115.3 0.1 1.8e-18 67.1 0.0 3.4 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 EPX73136.1 - 5e-14 51.5 4.6 5e-14 51.5 3.2 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EPX73136.1 - 2e-13 51.0 9.1 0.00012 22.2 0.1 4.2 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 EPX73136.1 - 2.9e-10 39.7 4.0 0.0034 16.6 0.8 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 EPX73136.1 - 2.5e-08 33.1 3.6 2.5e-08 33.1 2.5 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_15 PF13175.1 EPX73136.1 - 6e-08 32.1 0.2 1.1 8.1 0.0 4.4 3 1 0 4 4 4 2 AAA ATPase domain Fer4_6 PF12837.2 EPX73136.1 - 7e-06 25.6 11.2 2e-05 24.2 1.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.1 EPX73136.1 - 7.2e-06 26.1 0.1 0.0017 18.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPX73136.1 - 1.4e-05 24.5 0.4 0.075 12.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 EPX73136.1 - 3e-05 24.2 0.0 0.024 14.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EPX73136.1 - 0.00013 22.4 1.2 0.0055 17.1 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein Fer4_21 PF14697.1 EPX73136.1 - 0.00016 21.4 11.2 0.00029 20.6 7.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain DUF258 PF03193.11 EPX73136.1 - 0.00017 20.8 2.6 0.12 11.5 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function, DUF258 Fer4_2 PF12797.2 EPX73136.1 - 0.0004 20.1 12.5 0.001 18.8 1.7 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.1 EPX73136.1 - 0.00061 19.8 0.1 0.15 12.0 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain Fer4_7 PF12838.2 EPX73136.1 - 0.00085 19.6 1.6 0.00085 19.6 1.1 2.3 1 1 2 3 3 3 2 4Fe-4S dicluster domain RNA_helicase PF00910.17 EPX73136.1 - 0.0012 19.0 0.1 0.26 11.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase UPF0079 PF02367.12 EPX73136.1 - 0.0013 18.3 1.7 0.012 15.2 0.1 2.7 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EPX73136.1 - 0.0013 18.4 1.2 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.10 EPX73136.1 - 0.0023 16.6 0.0 0.18 10.4 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Fer4_9 PF13187.1 EPX73136.1 - 0.0023 18.1 2.1 0.0023 18.1 1.5 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_25 PF13481.1 EPX73136.1 - 0.0024 17.3 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.1 EPX73136.1 - 0.003 17.3 1.4 0.003 17.3 1.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_17 PF13207.1 EPX73136.1 - 0.0031 18.3 0.5 2.9 8.7 0.0 3.1 2 1 1 3 3 3 0 AAA domain Fer4_16 PF13484.1 EPX73136.1 - 0.0034 18.1 4.9 0.0035 18.0 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_18 PF13238.1 EPX73136.1 - 0.004 17.4 0.2 2.5 8.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain VirE PF05272.6 EPX73136.1 - 0.0043 16.5 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 1 Virulence-associated protein E AAA_5 PF07728.9 EPX73136.1 - 0.0044 16.7 0.4 0.28 10.8 0.0 3.0 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EPX73136.1 - 0.0056 16.5 0.0 0.26 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_3 PF12798.2 EPX73136.1 - 0.0061 17.0 5.0 0.0061 17.0 3.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain SbcCD_C PF13558.1 EPX73136.1 - 0.0088 15.9 0.0 5.1 7.0 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EPX73136.1 - 0.013 15.1 2.2 0.72 9.5 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EPX73136.1 - 0.015 14.4 0.1 0.036 13.1 0.1 1.6 1 0 0 1 1 1 0 KaiC SRP54 PF00448.17 EPX73136.1 - 0.019 14.3 3.4 0.22 10.9 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 EPX73136.1 - 0.027 14.4 1.7 0.29 11.0 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EPX73136.1 - 0.033 14.5 7.4 0.042 14.1 0.2 2.6 2 1 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 EPX73136.1 - 0.036 14.0 9.0 0.082 12.9 6.2 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.1 EPX73136.1 - 0.036 14.4 0.5 0.036 14.4 0.3 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_28 PF13521.1 EPX73136.1 - 0.045 13.7 0.1 2 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EPX73136.1 - 0.046 13.2 3.0 0.1 12.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EPX73136.1 - 0.049 12.4 1.5 5.6 5.7 0.2 2.4 3 0 0 3 3 2 0 NB-ARC domain DUF815 PF05673.8 EPX73136.1 - 0.059 12.2 0.2 2.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 EPX73136.1 - 0.11 12.0 0.3 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 EPX73136.1 - 0.14 12.5 13.5 0.044 14.1 1.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_14 PF13173.1 EPX73136.1 - 0.24 11.2 4.0 2.5 8.0 0.1 3.2 2 2 1 3 3 3 0 AAA domain AAA_10 PF12846.2 EPX73136.1 - 0.26 10.7 2.5 13 5.0 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain NTPase_1 PF03266.10 EPX73136.1 - 0.27 10.9 2.2 10 5.7 0.1 2.7 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.21 EPX73136.1 - 0.36 10.2 1.6 0.96 8.9 0.0 2.3 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_13 PF13166.1 EPX73136.1 - 0.54 8.6 2.2 1.8 6.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain Fer4_15 PF13459.1 EPX73136.1 - 4.5 7.9 8.4 0.13 12.8 0.6 2.3 2 0 0 2 2 1 0 4Fe-4S single cluster domain Fer4_18 PF13746.1 EPX73136.1 - 6.1 7.3 11.2 0.16 12.4 2.5 2.1 1 1 0 2 2 1 0 4Fe-4S dicluster domain S-AdoMet_synt_C PF02773.11 EPX73137.1 - 1.2e-73 245.3 0.1 1.9e-73 244.6 0.1 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EPX73137.1 - 3.7e-47 159.1 0.0 8e-47 158.1 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EPX73137.1 - 4.7e-44 148.7 0.2 9.9e-44 147.6 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Zeta_toxin PF06414.7 EPX73138.1 - 3.7e-06 26.1 0.0 6.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EPX73138.1 - 8.3e-05 23.4 0.0 0.00028 21.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPX73138.1 - 0.0002 21.4 0.0 0.00048 20.1 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EPX73138.1 - 0.00054 19.8 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EPX73138.1 - 0.00072 18.3 0.0 0.0016 17.2 0.0 1.5 1 1 0 1 1 1 1 PrkA AAA domain KAP_NTPase PF07693.9 EPX73138.1 - 0.001 18.1 0.0 0.0011 18.0 0.0 1.4 1 1 0 1 1 1 1 KAP family P-loop domain PRK PF00485.13 EPX73138.1 - 0.0013 18.3 0.0 0.0027 17.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.1 EPX73138.1 - 0.0016 18.0 0.2 0.94 9.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPX73138.1 - 0.0021 18.3 0.3 0.0057 16.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPX73138.1 - 0.0078 16.5 0.0 0.017 15.3 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ArgK PF03308.11 EPX73138.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein ATP_bind_1 PF03029.12 EPX73138.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 EPX73138.1 - 0.016 14.9 0.0 0.21 11.2 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EPX73138.1 - 0.021 14.2 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 EPX73138.1 - 0.032 13.9 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EPX73138.1 - 0.037 13.5 0.0 0.088 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.15 EPX73138.1 - 0.04 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Arch_ATPase PF01637.13 EPX73138.1 - 0.043 13.5 0.0 0.092 12.4 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase KTI12 PF08433.5 EPX73138.1 - 0.05 12.7 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_23 PF13476.1 EPX73138.1 - 0.056 13.7 1.9 0.22 11.7 1.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPX73138.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EPX73138.1 - 0.085 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EPX73138.1 - 0.099 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 EPX73138.1 - 0.1 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EPX73138.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EPX73138.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Thymidylate_kin PF02223.12 EPX73138.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.1 EPX73138.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain FA_hydroxylase PF04116.8 EPX73139.1 - 1.3e-15 57.8 22.4 1.3e-15 57.8 15.5 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Sprouty PF05210.8 EPX73139.1 - 0.049 13.6 0.5 7.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Sprouty protein (Spry) DUF2011 PF09428.5 EPX73141.1 - 2.7e-16 59.6 12.4 2.7e-16 59.6 8.6 1.8 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) UCH_1 PF13423.1 EPX73141.1 - 0.78 9.1 5.5 1.2 8.4 3.8 1.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase FliJ PF02050.11 EPX73141.1 - 4.5 7.3 8.6 0.64 10.0 2.9 1.9 2 0 0 2 2 2 0 Flagellar FliJ protein RabGAP-TBC PF00566.13 EPX73142.1 - 1.2e-32 113.1 16.2 4.7e-32 111.2 11.2 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EPX73142.1 - 3.4e-09 36.2 0.0 0.00054 19.3 0.0 3.6 2 1 0 3 3 3 3 Domain of unknown function (DUF3548) Peptidase_M18 PF02127.10 EPX73143.1 - 1.8e-175 583.5 0.0 2.1e-175 583.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EPX73143.1 - 0.00012 20.9 0.0 0.0011 17.8 0.0 2.0 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase Baculo_PEP_C PF04513.7 EPX73144.1 - 0.055 13.2 10.4 0.38 10.5 5.4 2.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2935 PF11155.3 EPX73144.1 - 0.055 13.5 2.4 0.53 10.3 1.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) DUF445 PF04286.7 EPX73144.1 - 0.079 12.4 3.8 0.13 11.7 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HutP PF09021.6 EPX73144.1 - 0.079 13.1 0.2 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 HutP IncA PF04156.9 EPX73144.1 - 0.4 10.2 2.3 0.75 9.3 1.6 1.5 1 0 0 1 1 1 0 IncA protein ERG4_ERG24 PF01222.12 EPX73145.1 - 8.2e-173 574.8 22.1 9.5e-173 574.6 15.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EPX73145.1 - 0.046 13.8 0.3 0.046 13.8 0.2 3.0 2 2 0 2 2 2 0 Phospholipid methyltransferase Cofilin_ADF PF00241.15 EPX73146.1 - 8.8e-45 151.6 0.1 9.9e-45 151.5 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein UPF0061 PF02696.9 EPX73147.1 - 2.6e-113 378.9 0.0 3.1e-113 378.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family XRCC4 PF06632.7 EPX73147.1 - 0.055 12.3 0.0 0.27 10.0 0.0 1.9 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Hus1 PF04005.7 EPX73148.1 - 1.2e-91 306.6 0.2 1.4e-91 306.5 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein Pkinase PF00069.20 EPX73149.1 - 8.6e-36 123.4 0.0 1e-22 80.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73149.1 - 1.9e-17 63.1 0.0 5.8e-10 38.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase FH2 PF02181.18 EPX73150.1 - 1e-68 231.9 4.6 1e-68 231.9 3.2 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EPX73150.1 - 1.8e-36 125.2 2.5 1.8e-36 125.2 1.7 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EPX73150.1 - 2e-07 30.6 2.9 2e-07 30.6 2.0 2.6 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_DAD PF06345.6 EPX73150.1 - 0.038 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 DRF Autoregulatory Domain DUF1645 PF07816.6 EPX73150.1 - 0.71 10.2 6.0 1.5 9.2 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) ABC_tran PF00005.22 EPX73151.1 - 2.6e-18 66.6 0.0 1.5e-17 64.2 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EPX73151.1 - 6.4e-13 49.3 0.8 4.2e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_25 PF13481.1 EPX73151.1 - 1.9e-06 27.4 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EPX73151.1 - 3.2e-06 26.4 0.0 0.035 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EPX73151.1 - 4e-05 23.0 0.1 8.7e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EPX73151.1 - 0.00024 20.6 0.0 0.00041 19.8 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain DUF258 PF03193.11 EPX73151.1 - 0.0007 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRP54 PF00448.17 EPX73151.1 - 0.0024 17.3 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SMC_N PF02463.14 EPX73151.1 - 0.0028 16.9 0.0 0.87 8.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPX73151.1 - 0.0052 17.1 0.0 0.0087 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPX73151.1 - 0.0054 17.5 0.0 0.01 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EPX73151.1 - 0.0054 16.2 0.1 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EPX73151.1 - 0.0064 16.4 0.0 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EPX73151.1 - 0.0068 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EPX73151.1 - 0.0071 16.3 1.0 0.014 15.3 0.7 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPX73151.1 - 0.02 15.0 0.0 0.054 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EPX73151.1 - 0.022 12.1 0.3 0.034 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_28 PF13521.1 EPX73151.1 - 0.027 14.4 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EPX73151.1 - 0.034 13.7 0.2 4.9 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EPX73151.1 - 0.037 14.2 0.5 0.54 10.4 0.2 2.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EPX73151.1 - 0.039 13.6 0.1 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EPX73151.1 - 0.088 12.5 0.1 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EPX73151.1 - 0.098 12.5 1.0 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EPX73151.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.7 2 0 0 2 2 1 0 Miro-like protein ArgK PF03308.11 EPX73151.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein PduV-EutP PF10662.4 EPX73151.1 - 0.14 11.6 0.1 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PI-PLC-X PF00388.14 EPX73152.1 - 6.2e-60 200.8 0.0 1.5e-59 199.6 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EPX73152.1 - 5.1e-37 126.4 0.1 1.3e-36 125.1 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EPX73152.1 - 4.2e-10 39.5 0.5 5.8e-09 35.8 0.1 2.9 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EPX73152.1 - 7.8e-08 32.0 0.0 2.4e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.1 EPX73152.1 - 0.0011 18.6 0.4 3.1 7.9 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EPX73152.1 - 0.0014 18.6 0.1 0.0075 16.3 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EPX73152.1 - 0.01 15.4 0.1 0.024 14.2 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 EPX73152.1 - 0.15 11.3 0.5 1.6 8.1 0.0 2.8 3 0 0 3 3 3 0 EF hand EF-hand_10 PF14788.1 EPX73152.1 - 0.28 10.8 3.7 0.11 12.1 0.2 2.2 2 0 0 2 2 2 0 EF hand Cullin_binding PF03556.10 EPX73152.1 - 0.28 11.3 3.3 0.2 11.8 0.1 2.4 3 0 0 3 3 3 0 Cullin binding DUF3974 PF13120.1 EPX73153.1 - 0.078 12.8 0.2 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) DUF382 PF04037.8 EPX73154.1 - 6.5e-60 200.6 0.1 6.5e-60 200.6 0.1 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF382) PSP PF04046.11 EPX73154.1 - 1.3e-24 85.3 2.4 2.5e-24 84.3 1.7 1.5 1 0 0 1 1 1 1 PSP Nop53 PF07767.6 EPX73155.1 - 4.8e-86 289.1 27.8 6.1e-86 288.8 19.3 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) PWWP PF00855.12 EPX73155.1 - 1.3 9.2 0.0 1.3 9.2 0.0 3.0 3 0 0 3 3 3 0 PWWP domain Sec23_trunk PF04811.10 EPX73156.1 - 2.5e-76 256.2 0.0 4.9e-76 255.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPX73156.1 - 3.1e-22 77.9 1.4 5.9e-22 77.0 0.1 2.2 3 0 0 3 3 3 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPX73156.1 - 4.2e-17 62.4 0.0 8.7e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EPX73156.1 - 2.9e-14 52.3 5.7 5.4e-14 51.4 3.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EPX73156.1 - 1.9e-08 33.8 0.0 4.3e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Myb_DNA-bind_6 PF13921.1 EPX73157.1 - 1.5e-19 69.8 13.4 2.1e-12 46.9 0.3 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPX73157.1 - 2.4e-18 65.8 9.1 3.2e-11 43.1 0.8 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Prp19_bind PF06991.6 EPX73158.1 - 1.6e-67 227.6 27.0 1.6e-67 227.6 18.7 2.7 2 1 1 3 3 3 1 Splicing factor, Prp19-binding domain IGF2_C PF08365.6 EPX73158.1 - 0.0048 16.6 2.9 0.008 15.9 0.9 2.2 1 1 1 2 2 2 1 Insulin-like growth factor II E-peptide DUF1713 PF08213.6 EPX73159.1 - 8.1e-13 47.7 22.1 1.1e-12 47.2 15.3 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 EPX73159.1 - 0.00011 22.1 0.5 0.00017 21.5 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial protein Pet20 PTPA PF03095.10 EPX73160.1 - 1.6e-109 365.6 0.0 1.9e-109 365.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein FSH1 PF03959.8 EPX73160.1 - 0.15 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Band_7 PF01145.20 EPX73161.1 - 4.9e-26 91.7 9.1 1e-25 90.6 4.3 2.1 1 1 1 2 2 2 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 EPX73161.1 - 0.0027 17.2 1.2 1.2 8.6 1.1 2.1 2 0 0 2 2 2 2 Enhancer of Polycomb C-terminus UcrQ PF02939.11 EPX73162.1 - 2.1e-37 126.8 0.3 2.4e-37 126.6 0.2 1.0 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 EPX73162.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) RNase_T PF00929.19 EPX73163.1 - 9.5e-16 58.5 0.0 1.5e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EPX73163.1 - 0.0003 20.3 0.0 0.00055 19.4 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease FYDLN_acid PF09538.5 EPX73163.1 - 1.9 9.0 4.8 19 5.8 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DSPn PF14671.1 EPX73164.1 - 5.7e-51 172.2 0.2 6.7e-49 165.5 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EPX73164.1 - 8.1e-17 61.0 0.0 2.9e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPX73164.1 - 2.2e-07 30.4 0.0 4.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EPX73164.1 - 3.2e-05 23.9 0.0 6.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 EPX73164.1 - 0.055 12.9 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 EPX73164.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Lin-8 PF03353.10 EPX73164.1 - 2.5 7.3 5.1 3.6 6.8 3.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ribosomal_L7Ae PF01248.21 EPX73165.1 - 3.3e-27 93.8 0.7 8.2e-27 92.5 0.3 1.7 1 1 1 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF423 PF04241.10 EPX73166.1 - 1.5e-23 82.5 0.8 2.4e-23 81.8 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) APS_kinase PF01583.15 EPX73167.1 - 2.8e-72 241.5 0.0 3.5e-72 241.2 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EPX73167.1 - 1.5e-07 31.3 0.0 2.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPX73167.1 - 3.9e-05 24.4 0.0 5.8e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EPX73167.1 - 0.00018 20.8 0.0 0.00029 20.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EPX73167.1 - 0.00033 20.9 0.1 0.00072 19.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EPX73167.1 - 0.0068 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain CPT PF07931.7 EPX73167.1 - 0.0091 15.6 0.3 0.15 11.6 0.2 2.2 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein 6PF2K PF01591.13 EPX73167.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ABC_tran PF00005.22 EPX73167.1 - 0.05 13.8 0.0 0.06 13.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EPX73167.1 - 0.058 13.7 0.1 0.061 13.6 0.1 1.3 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 EPX73167.1 - 0.071 12.6 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Vps23_core PF09454.5 EPX73168.1 - 3.2e-10 39.4 0.1 5.9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain XH PF03469.9 EPX73168.1 - 0.063 12.9 1.9 0.13 11.9 1.3 1.5 1 0 0 1 1 1 0 XH domain Cgr1 PF03879.9 EPX73168.1 - 0.87 9.7 8.0 1.6 8.9 5.6 1.3 1 0 0 1 1 1 0 Cgr1 family DUF1771 PF08590.5 EPX73170.1 - 7.1e-20 70.7 12.2 1.4e-19 69.8 8.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EPX73170.1 - 4.2e-19 68.5 0.2 8.7e-19 67.5 0.1 1.6 1 0 0 1 1 1 1 Smr domain DUF3368 PF11848.3 EPX73170.1 - 0.018 14.5 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) OmpH PF03938.9 EPX73170.1 - 3.2 7.6 5.7 8 6.3 0.7 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) STE2 PF02116.10 EPX73171.1 - 1.2e-54 185.3 26.2 1.4e-54 185.0 18.2 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Actin PF00022.14 EPX73172.1 - 4.3e-120 400.7 0.0 5.2e-120 400.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPX73172.1 - 0.0055 15.3 0.0 0.1 11.1 0.0 2.5 1 1 0 1 1 1 1 MreB/Mbl protein Cut8_C PF08559.5 EPX73173.1 - 0.019 14.8 0.2 0.033 13.9 0.2 1.4 1 0 0 1 1 1 0 Cut8 six-helix bundle TPT PF03151.11 EPX73174.1 - 1.5e-06 27.9 33.7 8.1e-06 25.5 10.3 3.0 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EPX73174.1 - 7.6e-05 22.7 37.6 0.028 14.4 11.0 2.5 2 0 0 2 2 2 2 EamA-like transporter family FLILHELTA PF10306.4 EPX73174.1 - 0.023 14.7 1.7 0.058 13.4 1.2 1.7 1 0 0 1 1 1 0 Hypothetical protein FLILHELTA UAA PF08449.6 EPX73174.1 - 0.032 13.1 30.4 0.31 9.9 21.1 2.4 1 1 0 1 1 1 0 UAA transporter family DUF1240 PF06836.7 EPX73175.1 - 0.22 11.7 3.8 0.17 12.1 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1240) VirB3 PF05101.8 EPX73175.1 - 0.23 11.4 1.5 0.29 11.1 1.0 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Ndc1_Nup PF09531.5 EPX73175.1 - 1.8 6.8 8.6 2.1 6.6 6.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Oxidored_q2 PF00420.19 EPX73175.1 - 3.9 7.1 8.2 7.2 6.2 5.6 1.5 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Glyco_transf_20 PF00982.16 EPX73176.1 - 2.5e-140 468.1 0.1 3.3e-140 467.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EPX73176.1 - 2.7e-28 98.4 0.0 4.2e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Proteasome PF00227.21 EPX73177.1 - 3.7e-32 111.1 0.0 1.1e-31 109.6 0.0 1.7 1 1 0 1 1 1 1 Proteasome subunit Ilm1 PF10311.4 EPX73178.1 - 6.1e-28 97.3 6.5 1.1e-27 96.6 4.5 1.3 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Ecm29 PF13001.2 EPX73179.1 - 3.5e-57 194.0 4.1 2.8e-29 102.0 0.0 2.7 1 1 0 2 2 2 2 Proteasome stabiliser Vac14_Fab1_bd PF12755.2 EPX73179.1 - 2.2e-08 34.3 1.0 0.034 14.5 0.0 5.3 5 0 0 5 5 5 3 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EPX73179.1 - 4.5e-07 29.4 1.0 1.8 8.8 0.0 6.8 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EPX73179.1 - 2.4e-05 24.5 0.2 1.7 8.9 0.0 5.8 4 1 0 4 4 4 1 HEAT repeats Sigma70_r2 PF04542.9 EPX73179.1 - 0.1 12.1 0.4 21 4.8 0.0 3.0 3 0 0 3 3 3 0 Sigma-70 region 2 Peptidase_C97 PF05903.9 EPX73180.1 - 7.4e-32 110.2 0.0 1.2e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EPX73180.1 - 0.0017 18.2 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase P5CR_dimer PF14748.1 EPX73181.1 - 4.8e-34 116.5 2.3 7.8e-34 115.9 1.2 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EPX73181.1 - 1.7e-11 44.4 1.2 8.4e-11 42.1 0.2 2.7 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EPX73181.1 - 0.064 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RnfC_N PF13375.1 EPX73181.1 - 0.1 12.3 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain TFIIS_C PF01096.13 EPX73182.1 - 1.6e-12 46.7 10.3 2.2e-12 46.3 0.9 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EPX73182.1 - 5.2e-12 45.2 1.6 5.2e-12 45.2 1.1 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Elf1 PF05129.8 EPX73182.1 - 0.00041 19.9 2.7 0.064 12.9 0.1 2.1 2 0 0 2 2 2 2 Transcription elongation factor Elf1 like DZR PF12773.2 EPX73182.1 - 0.0045 16.7 7.2 0.16 11.8 0.2 2.7 2 1 0 2 2 2 2 Double zinc ribbon DUF3716 PF12511.3 EPX73182.1 - 0.013 15.0 4.4 1.3 8.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Lar_restr_allev PF14354.1 EPX73182.1 - 0.037 14.3 0.9 0.037 14.3 0.6 2.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar mono-CXXC PF15626.1 EPX73182.1 - 0.1 12.5 0.2 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 single CXXC unit Ribosomal_L44 PF00935.14 EPX73182.1 - 0.11 12.5 2.9 1.5 8.9 0.2 2.7 2 1 1 3 3 3 0 Ribosomal protein L44 Terminase_GpA PF05876.7 EPX73182.1 - 0.38 9.0 2.3 0.38 9.0 0.9 1.5 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) Zn_Tnp_IS1595 PF12760.2 EPX73182.1 - 0.44 10.4 11.1 0.057 13.2 1.7 2.6 2 2 1 3 3 3 0 Transposase zinc-ribbon domain Cytochrome_C554 PF13435.1 EPX73182.1 - 0.58 10.2 5.5 0.14 12.2 1.9 1.4 2 0 0 2 2 1 0 Cytochrome c554 and c-prime C1_4 PF07975.7 EPX73182.1 - 0.64 10.0 8.0 0.79 9.7 0.4 3.0 2 2 0 2 2 2 0 TFIIH C1-like domain zf-3CxxC PF13695.1 EPX73182.1 - 0.97 9.7 6.3 4 7.7 2.9 2.2 1 1 1 2 2 2 0 Zinc-binding domain DUF2082 PF09855.4 EPX73182.1 - 1.2 9.0 9.2 2 8.3 0.1 3.5 2 2 1 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF3268 PF11672.3 EPX73182.1 - 1.2 9.2 4.8 4 7.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) HypA PF01155.14 EPX73182.1 - 1.8 8.3 6.5 3 7.5 0.9 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family ADK_lid PF05191.9 EPX73182.1 - 1.9 8.1 7.5 12 5.6 0.2 3.8 4 0 0 4 4 4 0 Adenylate kinase, active site lid Cytochrome_C7 PF14522.1 EPX73182.1 - 2.5 7.8 8.4 32 4.2 5.8 2.3 1 1 0 1 1 1 0 Cytochrome c7 OrfB_Zn_ribbon PF07282.6 EPX73182.1 - 4.7 6.9 6.9 6.6 6.4 1.1 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 EPX73182.1 - 4.7 7.2 10.2 3.1 7.8 0.0 3.6 3 1 0 3 3 3 0 Zinc ribbon domain zf-IS66 PF13005.2 EPX73182.1 - 4.7 7.2 8.9 30 4.7 0.1 3.6 3 1 1 4 4 4 0 zinc-finger binding domain of transposase IS66 zinc-ribbons_6 PF07191.7 EPX73182.1 - 4.9 7.0 7.3 0.86 9.4 0.3 2.5 2 1 0 2 2 2 0 zinc-ribbons zf-RING_3 PF14369.1 EPX73182.1 - 5.5 7.0 7.7 15 5.6 0.8 2.6 3 0 0 3 3 3 0 zinc-finger PH PF00169.24 EPX73183.1 - 1.7e-09 37.8 0.1 7.4e-09 35.7 0.0 2.1 1 0 0 1 1 1 1 PH domain Anillin PF08174.6 EPX73183.1 - 0.00058 19.9 0.5 0.0019 18.2 0.0 2.1 2 0 0 2 2 2 1 Cell division protein anillin PH_11 PF15413.1 EPX73183.1 - 5.3 7.3 5.9 73 3.6 0.3 3.5 2 1 0 2 2 2 0 Pleckstrin homology domain SIN1 PF05422.7 EPX73184.1 - 4e-133 444.6 4.0 5.2e-133 444.3 2.8 1.1 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EPX73184.1 - 0.14 12.1 0.5 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 GLUT4 regulating protein TUG TFIIE_alpha PF02002.12 EPX73185.1 - 1.3e-14 53.5 0.2 3.8e-14 52.0 0.1 1.8 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EPX73185.1 - 0.0029 16.9 1.0 0.013 14.7 0.7 2.2 1 0 0 1 1 1 1 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 EPX73185.1 - 0.061 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF4428 PF14471.1 EPX73185.1 - 0.084 12.6 4.2 0.34 10.6 0.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) zf-C2H2_6 PF13912.1 EPX73185.1 - 0.47 10.4 0.1 0.47 10.4 0.1 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger WD40 PF00400.27 EPX73186.1 - 7.8e-11 41.4 1.6 0.00098 18.9 1.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat PI3Ka PF00613.15 EPX73187.1 - 2.8e-67 225.4 1.7 5.4e-67 224.5 1.2 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EPX73187.1 - 2.2e-47 161.4 0.3 3.5e-46 157.5 0.0 2.8 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EPX73187.1 - 8.6e-19 67.7 0.2 1.5e-18 66.9 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.1 EPX73187.1 - 0.0038 16.2 0.0 0.0098 14.9 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4135) DLIC PF05783.6 EPX73188.1 - 5.9e-11 41.7 1.0 9.2e-11 41.0 0.3 1.6 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) APG12 PF04110.8 EPX73188.1 - 0.057 13.6 1.4 1.1 9.5 0.0 2.7 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 Telomere_reg-2 PF10193.4 EPX73189.1 - 9.5e-27 93.5 0.0 2.8e-26 91.9 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein Spectrin PF00435.16 EPX73190.1 - 0.00086 19.5 5.0 0.00086 19.5 3.4 4.1 2 1 1 4 4 4 2 Spectrin repeat WXG100 PF06013.7 EPX73190.1 - 0.042 13.8 8.6 3.4 7.7 0.0 4.7 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Reo_sigmaC PF04582.7 EPX73190.1 - 0.071 12.2 10.5 0.074 12.2 1.8 2.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EPX73190.1 - 0.23 11.3 15.1 0.9 9.3 5.1 3.7 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 EPX73190.1 - 0.28 10.7 41.8 1.3 8.5 6.0 4.3 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 EPX73190.1 - 1.6 8.7 24.2 0.31 10.9 0.3 5.7 3 3 3 6 6 6 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.8 EPX73190.1 - 1.6 9.4 36.8 0.48 11.1 2.5 4.7 3 1 1 4 4 4 0 Occludin homology domain IncA PF04156.9 EPX73190.1 - 4.2 6.9 50.2 0.02 14.5 7.8 4.3 2 1 1 3 3 3 0 IncA protein HBS1_N PF08938.5 EPX73190.1 - 4.3 7.5 10.5 0.9 9.7 1.0 3.9 4 1 0 4 4 4 0 HBS1 N-terminus Allexi_40kDa PF05549.6 EPX73190.1 - 4.9 6.3 19.6 0.28 10.4 2.0 3.7 2 1 2 4 4 4 0 Allexivirus 40kDa protein Nol1_Nop2_Fmu PF01189.12 EPX73191.1 - 1.3e-32 113.3 0.0 5.9e-17 61.9 0.0 3.7 2 1 1 3 3 3 3 NOL1/NOP2/sun family FtsJ PF01728.14 EPX73191.1 - 0.016 15.1 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Cation_efflux PF01545.16 EPX73192.1 - 1.9e-56 191.2 5.1 1.9e-56 191.2 3.5 2.1 2 0 0 2 2 2 1 Cation efflux family CDC45 PF02724.9 EPX73193.1 - 9.1e-217 720.9 1.1 1e-216 720.7 0.8 1.0 1 0 0 1 1 1 1 CDC45-like protein DHH PF01368.15 EPX73193.1 - 0.0054 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 DHH family DUF416 PF04222.7 EPX73193.1 - 0.04 13.0 0.1 0.077 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF416) SNF2_N PF00176.18 EPX73194.1 - 4.7e-58 196.3 0.1 4.7e-58 196.3 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EPX73194.1 - 2.7e-09 36.7 11.1 9.8e-09 34.9 7.7 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPX73194.1 - 1.3e-07 31.1 9.9 5.3e-07 29.1 6.9 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPX73194.1 - 1.8e-07 31.0 11.8 1.8e-07 31.0 8.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX73194.1 - 1.9e-07 30.6 9.4 1.9e-07 30.6 6.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX73194.1 - 5.2e-05 22.8 10.0 5.2e-05 22.8 6.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EPX73194.1 - 6.1e-05 22.4 4.3 0.00014 21.3 2.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Helicase_C PF00271.26 EPX73194.1 - 0.00023 20.9 0.0 0.00059 19.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 EPX73194.1 - 0.0058 16.4 8.9 0.015 15.1 6.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPX73194.1 - 0.016 14.8 4.9 0.1 12.3 3.4 2.4 1 1 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 EPX73194.1 - 0.038 14.0 11.4 0.19 11.8 7.9 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger zf-P11 PF03854.9 EPX73194.1 - 2.4 7.7 14.5 1.4 8.4 4.8 3.1 2 1 1 3 3 3 0 P-11 zinc finger Adaptin_N PF01602.15 EPX73195.1 - 3.5e-93 312.7 17.9 4.2e-93 312.4 12.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EPX73195.1 - 2.6e-05 24.4 0.3 0.0033 17.6 0.0 3.3 3 1 0 3 3 3 1 HEAT repeats Cnd1 PF12717.2 EPX73195.1 - 6.5e-05 22.8 9.9 0.0095 15.8 0.1 2.9 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EPX73195.1 - 6.5e-05 22.6 4.3 1.8 8.8 0.1 4.6 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 EPX73195.1 - 0.036 14.5 0.6 48 4.6 0.0 4.0 3 0 0 3 3 3 0 HEAT-like repeat ATP_bind_1 PF03029.12 EPX73196.1 - 3.6e-80 268.9 0.0 4.5e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EPX73196.1 - 0.00029 20.2 0.0 0.00062 19.2 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EPX73196.1 - 0.0022 18.8 2.9 0.017 15.8 2.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EPX73196.1 - 0.0038 16.7 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 EPX73196.1 - 0.0048 16.8 0.0 0.66 9.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EPX73196.1 - 0.005 17.1 1.3 0.51 10.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain MipZ PF09140.6 EPX73196.1 - 0.0054 15.8 0.0 0.068 12.2 0.0 2.0 1 1 1 2 2 2 1 ATPase MipZ AAA_33 PF13671.1 EPX73196.1 - 0.02 14.7 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EPX73196.1 - 0.023 13.4 0.0 0.046 12.4 0.0 1.4 1 0 0 1 1 1 0 ArgK protein RNA_helicase PF00910.17 EPX73196.1 - 0.056 13.6 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.5 EPX73196.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EPX73196.1 - 0.11 11.6 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 EPX73196.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B HSCB_C PF07743.8 EPX73197.1 - 2.4e-17 63.1 0.8 3.9e-17 62.4 0.6 1.4 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EPX73197.1 - 9e-11 41.3 0.2 8e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain Mcm10 PF09332.6 EPX73197.1 - 0.089 12.1 0.5 0.095 12.0 0.4 1.2 1 0 0 1 1 1 0 Mcm10 replication factor FUSC-like PF12805.2 EPX73197.1 - 0.11 11.4 0.1 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS zf-C2H2 PF00096.21 EPX73198.1 - 6.1e-32 108.0 71.3 2e-05 24.6 0.4 10.3 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPX73198.1 - 1.2e-25 87.8 68.3 0.00068 19.7 1.0 10.2 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPX73198.1 - 3.5e-20 71.2 66.0 7.7e-05 22.7 0.2 10.9 10 1 1 11 11 11 7 Zinc-finger double domain zf-met PF12874.2 EPX73198.1 - 5.2e-07 29.6 22.8 0.07 13.3 0.1 6.7 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPX73198.1 - 4.5e-05 23.4 27.4 0.012 15.7 0.0 8.1 9 0 0 9 9 9 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EPX73198.1 - 0.0019 18.0 13.4 0.52 10.2 0.2 5.6 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EPX73198.1 - 0.0087 16.2 0.7 0.0087 16.2 0.5 9.8 11 1 0 11 11 11 2 C2H2-type zinc-finger domain zf-AN1 PF01428.11 EPX73198.1 - 0.036 13.9 0.4 0.036 13.9 0.3 4.6 5 1 0 5 5 5 0 AN1-like Zinc finger IBR PF01485.16 EPX73198.1 - 0.61 10.0 25.7 0.7 9.8 0.8 5.7 2 1 2 4 4 4 0 IBR domain GWT1 PF06423.7 EPX73199.1 - 5e-38 130.2 3.5 5e-38 130.2 2.4 3.2 3 1 0 3 3 3 1 GWT1 DUF1129 PF06570.6 EPX73199.1 - 0.016 14.5 8.7 0.12 11.6 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Herpes_pp38 PF04846.8 EPX73199.1 - 0.039 13.2 2.2 0.057 12.7 0.2 2.3 2 0 0 2 2 2 0 Herpesvirus pp38 phosphoprotein UPF0233 PF06781.7 EPX73199.1 - 0.36 10.4 4.0 2.2 7.9 0.1 3.3 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0233) Ribosomal_S17 PF00366.15 EPX73200.1 - 7.1e-31 106.0 1.4 1.1e-30 105.4 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Rib_5-P_isom_A PF06026.9 EPX73201.1 - 1.1e-54 184.3 0.0 1.4e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) WD40 PF00400.27 EPX73202.1 - 5.4e-33 111.6 14.3 1.2e-06 28.1 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EPX73202.1 - 6.3e-07 29.3 0.1 0.0003 20.5 0.1 2.7 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Kinesin PF00225.18 EPX73203.1 - 1.4e-64 217.9 0.0 1.9e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain PSD3 PF07626.6 EPX73203.1 - 0.015 15.2 1.8 2.8 8.0 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1587) Vps51 PF08700.6 EPX73204.1 - 5.6e-12 45.3 3.3 5.6e-12 45.3 2.3 3.4 3 1 0 3 3 3 1 Vps51/Vps67 UPF0118 PF01594.11 EPX73204.1 - 3.5 6.5 5.5 1.2 7.9 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF20 Atg14 PF10186.4 EPX73204.1 - 8.9 5.1 14.4 1.3 7.9 5.8 2.4 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF59 PF01883.14 EPX73205.1 - 7.1e-09 35.5 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF59 6PF2K PF01591.13 EPX73206.1 - 8.3e-53 178.7 2.7 1.2e-52 178.2 1.8 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EPX73206.1 - 2.3e-06 27.8 0.0 1.1e-05 25.5 0.0 2.0 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.5 EPX73206.1 - 3.2e-06 26.5 0.1 7.6e-06 25.3 0.1 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EPX73206.1 - 4.4e-06 26.6 0.0 9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF1887 PF09002.6 EPX73206.1 - 0.0034 15.8 1.0 0.0051 15.2 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1887) AAA_17 PF13207.1 EPX73206.1 - 0.12 13.1 0.3 0.38 11.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain UAA PF08449.6 EPX73207.1 - 2.3e-14 53.0 22.9 3.3e-14 52.5 15.9 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EPX73207.1 - 7.7e-11 41.8 7.8 7.7e-11 41.8 5.4 2.8 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EPX73207.1 - 0.0008 19.4 27.9 0.0014 18.6 5.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family PHO4 PF01384.15 EPX73207.1 - 0.0024 16.5 6.1 0.0024 16.5 4.2 2.6 1 1 1 2 2 2 1 Phosphate transporter family eRF1_2 PF03464.10 EPX73208.1 - 1.1e-45 155.2 0.1 1.9e-45 154.4 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EPX73208.1 - 2.4e-38 130.8 0.9 5e-38 129.8 0.6 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EPX73208.1 - 1.7e-25 89.1 0.1 4.2e-25 87.8 0.0 1.7 2 0 0 2 2 2 1 eRF1 domain 1 EPSP_synthase PF00275.15 EPX73209.1 - 3.5e-125 417.7 0.0 4.9e-125 417.2 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EPX73209.1 - 5.4e-96 320.5 0.0 8.3e-96 319.9 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EPX73209.1 - 3.3e-65 219.8 0.0 5.6e-65 219.1 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EPX73209.1 - 6.1e-35 120.4 0.1 5e-34 117.4 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EPX73209.1 - 6.1e-25 87.1 0.0 1.5e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EPX73209.1 - 1.2e-13 51.2 0.2 5e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EPX73209.1 - 6.3e-10 38.7 0.0 3.2e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EPX73209.1 - 1.9e-07 31.8 0.0 6.3e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPX73209.1 - 0.00098 19.4 0.2 0.004 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EPX73209.1 - 0.0018 18.1 0.2 0.013 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EPX73209.1 - 0.0097 16.1 0.0 0.058 13.6 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EPX73209.1 - 0.038 13.8 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain CoA_binding PF02629.14 EPX73209.1 - 0.054 14.0 0.7 0.46 11.0 0.0 2.6 3 0 0 3 3 2 0 CoA binding domain ThiF PF00899.16 EPX73209.1 - 0.098 12.4 2.4 0.2 11.4 0.0 2.8 4 0 0 4 4 3 0 ThiF family ABC_tran PF00005.22 EPX73209.1 - 0.1 12.8 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EPX73209.1 - 0.13 11.2 0.0 0.33 10.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Histone PF00125.19 EPX73210.1 - 7.2e-15 54.8 0.4 8.7e-15 54.6 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPX73210.1 - 7.1e-06 25.9 0.1 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EPX73210.1 - 5.8e-05 23.1 0.1 8.2e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EPX73210.1 - 8.5e-05 22.4 0.1 0.00012 21.9 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 EPX73210.1 - 0.012 14.8 0.0 0.013 14.8 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EPX73210.1 - 0.029 14.0 0.0 0.037 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated DUF1819 PF08849.6 EPX73210.1 - 0.1 12.0 0.6 0.36 10.2 0.1 1.8 1 1 1 2 2 2 0 Putative inner membrane protein (DUF1819) TFIID_20kDa PF03847.8 EPX73210.1 - 0.1 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 EPX73211.1 - 6.8e-32 109.4 0.1 1.1e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EPX73211.1 - 6.3e-06 26.2 0.0 9.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPX73211.1 - 0.0024 17.8 0.2 0.0056 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPX73211.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Glyco_transf_22 PF03901.12 EPX73212.1 - 2.4e-105 352.9 33.4 2.8e-105 352.7 23.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Mo25 PF08569.6 EPX73213.1 - 7e-122 406.6 15.1 7.8e-122 406.4 10.5 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 EPX73213.1 - 0.015 15.5 0.0 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats Kinesin PF00225.18 EPX73214.1 - 4.5e-111 370.7 1.8 7.5e-111 370.0 1.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF745 PF05335.8 EPX73214.1 - 5.7 6.4 8.5 0.16 11.5 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF745) DUF87 PF01935.12 EPX73214.1 - 7.1 6.3 8.4 8.3 6.1 0.2 3.3 3 1 0 3 3 3 0 Domain of unknown function DUF87 Response_reg PF00072.19 EPX73215.1 - 1.9e-20 72.9 0.1 7.9e-19 67.7 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EPX73215.1 - 2.7e-19 68.9 0.0 5.9e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EPX73215.1 - 8.9e-17 61.3 0.0 3.4e-11 43.4 0.0 2.7 2 0 0 2 2 2 2 PAS domain HisKA PF00512.20 EPX73215.1 - 2.1e-16 59.6 0.1 4.4e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EPX73215.1 - 1.7e-15 56.7 0.0 2.1e-09 37.1 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 EPX73215.1 - 3.2e-13 49.5 0.0 1.6e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EPX73215.1 - 1.2e-11 44.6 0.0 2e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 EPX73215.1 - 1.6e-07 30.9 0.0 0.0027 17.5 0.0 2.8 2 0 0 2 2 2 2 PAS domain AAA PF00004.24 EPX73216.1 - 6.1e-52 175.3 0.2 3.3e-40 137.3 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EPX73216.1 - 2.9e-11 43.1 0.0 5.8e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EPX73216.1 - 1.6e-10 40.4 0.1 1.3e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EPX73216.1 - 4.3e-09 36.5 0.5 0.00025 21.2 0.1 4.2 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.9 EPX73216.1 - 3.8e-08 33.4 0.0 1.6e-06 28.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EPX73216.1 - 5.8e-08 31.8 0.0 0.0026 16.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 EPX73216.1 - 7.7e-07 29.0 0.0 0.028 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EPX73216.1 - 2.1e-06 27.6 0.3 1.8 8.2 0.0 4.1 2 2 2 4 4 4 1 Archaeal ATPase AAA_16 PF13191.1 EPX73216.1 - 2.2e-06 27.8 0.0 0.0042 17.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EPX73216.1 - 2.4e-06 28.3 0.0 0.002 18.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPX73216.1 - 1.3e-05 24.3 0.2 0.033 13.2 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EPX73216.1 - 2.5e-05 23.9 1.5 0.022 14.4 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain AAA_18 PF13238.1 EPX73216.1 - 4.3e-05 23.8 0.1 0.0057 16.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPX73216.1 - 4.5e-05 23.1 0.0 0.0011 18.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EPX73216.1 - 0.00011 22.0 0.0 0.044 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPX73216.1 - 0.00022 20.6 0.2 1.1 8.5 0.0 3.5 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 EPX73216.1 - 0.00031 19.9 0.2 0.0069 15.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EPX73216.1 - 0.00071 19.0 0.1 0.45 9.9 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain UPF0079 PF02367.12 EPX73216.1 - 0.00075 19.1 0.1 0.98 9.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EPX73216.1 - 0.00077 18.6 0.1 0.51 9.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 EPX73216.1 - 0.0028 17.0 0.5 0.13 11.6 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein KaiC PF06745.8 EPX73216.1 - 0.006 15.7 0.3 0.038 13.1 0.1 2.2 2 0 0 2 2 2 1 KaiC RNA_helicase PF00910.17 EPX73216.1 - 0.0064 16.6 0.0 0.06 13.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 EPX73216.1 - 0.011 15.9 1.5 0.034 14.4 0.0 2.4 3 0 0 3 3 2 0 ABC transporter AAA_24 PF13479.1 EPX73216.1 - 0.014 14.9 1.0 0.075 12.6 0.2 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EPX73216.1 - 0.02 14.1 0.0 3.7 6.7 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein T2SE PF00437.15 EPX73216.1 - 0.024 13.5 0.3 4 6.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.1 EPX73216.1 - 0.035 14.0 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EPX73216.1 - 0.062 12.2 0.0 0.31 9.9 0.0 2.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EPX73216.1 - 0.075 12.6 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EPX73216.1 - 0.1 12.1 0.2 4.3 6.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.12 EPX73216.1 - 0.16 10.7 0.0 2.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 EPX73216.1 - 0.18 11.4 2.2 6.4 6.3 0.0 3.5 4 0 0 4 4 4 0 NACHT domain KTI12 PF08433.5 EPX73216.1 - 0.18 10.9 0.2 0.59 9.2 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF1301 PF06979.7 EPX73217.1 - 0.00026 21.1 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1301) Stk19 PF10494.4 EPX73218.1 - 4e-41 141.0 0.2 4e-41 141.0 0.1 1.4 2 0 0 2 2 2 1 Serine-threonine protein kinase 19 POTRA_2 PF08479.6 EPX73218.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 POTRA domain, ShlB-type tRNA-synt_1c PF00749.16 EPX73219.1 - 2.6e-103 344.9 0.0 3.9e-103 344.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 EPX73219.1 - 7.9e-48 162.0 1.9 1.4e-47 161.2 1.3 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 EPX73219.1 - 2.5e-33 115.2 0.1 1.6e-31 109.2 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 EPX73219.1 - 5.6e-18 65.4 5.6 1.2e-17 64.3 3.9 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Glyco_hydro_72 PF03198.9 EPX73220.1 - 2.5e-137 457.0 4.2 3.1e-137 456.7 2.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EPX73220.1 - 2.2e-05 23.8 0.8 0.00024 20.4 0.4 2.2 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EPX73220.1 - 0.0064 15.4 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Proteasom_Rpn13 PF04683.8 EPX73221.1 - 1.1e-24 86.3 0.0 1.9e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor AcetylCoA_hyd_C PF13336.1 EPX73221.1 - 0.073 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain DUF1400 PF07176.6 EPX73221.1 - 0.086 12.7 0.1 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) BRCT PF00533.21 EPX73222.1 - 9.1e-13 48.1 0.5 1.6e-10 40.9 0.1 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Rad9_Rad53_bind PF08605.5 EPX73222.1 - 1.8e-07 30.9 0.0 4.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Rho_RNA_bind PF07497.7 EPX73222.1 - 0.0094 15.5 0.0 3.9 7.1 0.0 2.6 2 0 0 2 2 2 2 Rho termination factor, RNA-binding domain DUF4537 PF15057.1 EPX73222.1 - 0.035 13.8 0.0 0.098 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) KAT11 PF08214.6 EPX73223.1 - 3.7e-58 197.2 0.9 4.4e-58 197.0 0.6 1.0 1 0 0 1 1 1 1 Histone acetylation protein SAC3_GANP PF03399.11 EPX73224.1 - 1.7e-25 89.8 0.0 2.4e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPX73224.1 - 1.6e-21 76.5 0.7 5.5e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 PCI PF01399.22 EPX73224.1 - 0.0044 17.3 0.4 0.16 12.2 0.1 2.5 2 1 0 2 2 2 1 PCI domain PfkB PF00294.19 EPX73225.1 - 3.9e-68 229.7 0.3 4.4e-68 229.6 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EPX73225.1 - 5.8e-09 35.4 0.1 8.7e-09 34.9 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TNF PF00229.13 EPX73225.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family WTF PF03303.8 EPX73226.1 - 7.5e-06 25.5 1.1 1.2e-05 24.8 0.7 1.4 1 1 0 1 1 1 1 WTF protein UPF0104 PF03706.8 EPX73226.1 - 0.00013 21.3 3.5 0.064 12.5 2.1 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0104) DUF3671 PF12420.3 EPX73226.1 - 0.5 10.3 9.8 2.2 8.3 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF1119 PF06550.6 EPX73226.1 - 0.69 8.9 10.1 0.17 10.9 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1119) DUF1129 PF06570.6 EPX73227.1 - 0.1 11.9 3.1 0.14 11.4 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Tic20 PF09685.5 EPX73227.1 - 0.17 11.9 14.1 0.57 10.1 9.7 1.8 1 1 0 1 1 1 0 Tic20-like protein FA_desaturase PF00487.19 EPX73227.1 - 2.9 7.2 5.6 7.8 5.8 3.9 1.7 1 1 0 1 1 1 0 Fatty acid desaturase zf-RING_2 PF13639.1 EPX73228.1 - 4.7e-08 32.7 6.5 9.5e-08 31.7 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPX73228.1 - 4.3e-07 29.8 4.6 7.9e-07 29.0 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX73228.1 - 5.6e-07 29.1 3.8 1e-06 28.2 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX73228.1 - 9.6e-07 28.3 6.8 1.6e-06 27.6 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPX73228.1 - 0.00011 22.2 4.8 0.00027 20.9 3.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPX73228.1 - 0.00056 19.5 4.9 0.0011 18.6 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain cIII PF08134.6 EPX73228.1 - 0.09 12.3 0.1 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 cIII protein family zf-Apc11 PF12861.2 EPX73228.1 - 0.15 11.9 2.8 0.28 11.0 1.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EPX73228.1 - 0.2 11.7 3.8 0.55 10.3 2.6 1.7 1 1 0 1 1 1 0 RING-variant domain Ribosomal_L13 PF00572.13 EPX73229.1 - 2.2e-44 150.6 0.0 2.5e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 Motile_Sperm PF00635.21 EPX73230.1 - 3.4e-24 84.5 0.1 6.3e-24 83.7 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Shisa PF13908.1 EPX73231.1 - 0.11 12.6 2.3 0.45 10.6 0.0 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EPX73231.1 - 0.12 12.7 0.1 0.42 11.0 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RAP1 PF07218.6 EPX73231.1 - 0.18 9.9 11.0 0.22 9.6 7.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ETRAMP PF09716.5 EPX73231.1 - 7.2 6.6 7.7 0.59 10.1 0.1 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Band_7 PF01145.20 EPX73232.1 - 4.9e-28 98.2 0.1 1e-27 97.1 0.1 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EPX73232.1 - 0.025 14.1 0.2 0.16 11.4 0.0 2.2 2 1 0 2 2 2 0 SPFH domain-Band 7 family PE PF00934.15 EPX73232.1 - 0.081 13.0 1.7 0.16 12.0 0.1 2.2 2 0 0 2 2 2 0 PE family Germane PF10646.4 EPX73232.1 - 0.088 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Sporulation and spore germination Glycos_transf_3 PF00591.16 EPX73233.1 - 1e-80 270.7 0.0 1.3e-80 270.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EPX73233.1 - 1.8e-07 30.6 0.0 3.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Peptidase_S10 PF00450.17 EPX73234.1 - 3.1e-102 342.8 1.1 3.6e-102 342.6 0.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EPX73234.1 - 0.086 12.7 0.0 0.26 11.1 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family RNase_PH PF01138.16 EPX73235.1 - 9.9e-17 61.4 0.1 1.6e-16 60.7 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EPX73235.1 - 0.035 14.0 0.3 0.2 11.6 0.2 2.3 2 1 1 3 3 3 0 3' exoribonuclease family, domain 2 BAG PF02179.11 EPX73236.1 - 7.5e-16 58.0 2.7 1.5e-15 57.0 1.9 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EPX73236.1 - 2e-07 30.3 0.2 4.2e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPX73236.1 - 8.4e-06 25.3 0.1 2.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.3 EPX73236.1 - 0.017 15.0 0.1 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 GLUT4 regulating protein TUG STAT_alpha PF01017.15 EPX73236.1 - 0.035 13.8 0.9 0.035 13.8 0.6 2.0 2 1 0 2 2 2 0 STAT protein, all-alpha domain DUF1828 PF08861.5 EPX73236.1 - 0.039 13.5 0.4 0.21 11.2 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function DUF1828 PB1 PF00564.19 EPX73236.1 - 0.076 12.6 0.2 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 PB1 domain Topoisom_bac PF01131.15 EPX73237.1 - 4.1e-88 295.9 0.0 5e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EPX73237.1 - 6.9e-21 74.0 0.0 1.2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Toprim domain OmpH PF03938.9 EPX73238.1 - 0.004 17.0 0.5 0.0047 16.8 0.3 1.0 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF4474 PF14751.1 EPX73238.1 - 0.013 14.7 0.3 0.017 14.3 0.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4474) Ribosomal_S3_C PF00189.15 EPX73239.1 - 8.1e-16 58.0 0.0 1.6e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EPX73239.1 - 2.9e-14 52.3 0.0 6e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 KH domain FAD_binding_9 PF08021.6 EPX73239.1 - 0.033 14.1 0.1 0.091 12.7 0.0 1.7 1 1 1 2 2 2 0 Siderophore-interacting FAD-binding domain UN_NPL4 PF11543.3 EPX73239.1 - 0.097 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Fork_head PF00250.13 EPX73240.1 - 2.9e-38 129.8 1.5 5.6e-38 128.8 1.0 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EPX73240.1 - 7.6e-08 32.3 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain Fungal_trans PF04082.13 EPX73241.1 - 8.7e-34 116.5 5.5 1.5e-33 115.8 3.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX73241.1 - 6.9e-13 48.2 11.7 1.2e-12 47.5 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERG4_ERG24 PF01222.12 EPX73242.1 - 4.5e-142 473.5 16.3 5.5e-142 473.2 11.3 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EPX73242.1 - 0.00075 18.8 2.6 0.00075 18.8 1.8 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF1295) Stb3 PF10330.4 EPX73243.1 - 1.2e-22 79.3 0.0 2.6e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Putative Sin3 binding protein NTR2 PF15458.1 EPX73243.1 - 0.0091 15.2 9.4 0.062 12.5 4.5 2.2 2 0 0 2 2 2 2 Nineteen complex-related protein 2 COPR5 PF15340.1 EPX73243.1 - 6.9 7.0 9.6 2 8.8 0.6 3.2 3 1 0 3 3 3 0 Cooperator of PRMT5 family AA_permease PF00324.16 EPX73244.1 - 1.2e-100 337.1 40.7 1.5e-100 336.8 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPX73244.1 - 9.4e-34 116.6 41.4 1.2e-33 116.3 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease Eaf7 PF07904.8 EPX73245.1 - 3.4e-17 62.2 0.0 9.1e-17 60.8 0.0 1.8 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 MBOAT PF03062.14 EPX73246.1 - 1.3e-59 201.9 7.9 1.3e-59 201.9 5.5 2.2 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family IMS PF00817.15 EPX73247.1 - 1.7e-39 134.9 0.0 4e-39 133.7 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family Acetyltransf_13 PF13880.1 EPX73247.1 - 1.1e-22 79.5 0.0 2.5e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EPX73247.1 - 7.7e-13 47.7 0.5 7.7e-13 47.7 0.3 3.1 3 0 0 3 3 3 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EPX73247.1 - 0.02 14.9 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPX73247.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IMS_HHH PF11798.3 EPX73247.1 - 0.073 13.1 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 IMS family HHH motif Abhydro_lipase PF04083.11 EPX73248.1 - 1.8e-20 72.0 0.1 3.7e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EPX73248.1 - 3.1e-18 66.1 0.0 6.7e-18 65.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPX73248.1 - 1.2e-08 35.1 0.0 2.5e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPX73248.1 - 2.1e-06 27.5 0.0 1.3e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EPX73248.1 - 0.00066 19.1 0.0 0.73 9.2 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) DLH PF01738.13 EPX73248.1 - 0.00072 18.9 0.0 0.0076 15.5 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EPX73248.1 - 0.13 11.7 0.3 12 5.2 0.1 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Alpha-amylase PF00128.19 EPX73249.1 - 5e-43 147.6 0.0 7.6e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EPX73249.1 - 5.7e-12 45.5 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DNA_pol_phi PF04931.8 EPX73249.1 - 1.1 6.9 5.5 1.5 6.5 3.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sod_Fe_C PF02777.13 EPX73250.1 - 2.7e-14 52.8 1.5 2.2e-07 30.6 0.2 2.3 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EPX73250.1 - 0.00054 20.1 0.4 0.0015 18.7 0.3 1.8 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Nepo_coat_N PF03689.10 EPX73250.1 - 0.042 13.5 0.0 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 Nepovirus coat protein, N-terminal domain PQ-loop PF04193.9 EPX73251.1 - 1.3e-28 98.2 6.5 1.6e-17 62.7 0.8 2.5 2 0 0 2 2 2 2 PQ loop repeat Peptidase_S8 PF00082.17 EPX73252.1 - 1.3e-51 175.4 5.6 2e-51 174.8 3.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EPX73252.1 - 1.4e-15 57.5 0.1 2.7e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 WD40 PF00400.27 EPX73253.1 - 4.7e-22 77.0 10.0 2.5e-05 23.9 0.2 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EPX73253.1 - 0.087 12.3 0.1 0.27 10.7 0.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C3H1 PF10650.4 EPX73254.1 - 7.5e-08 31.7 2.4 1.1e-07 31.1 1.7 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Bul1_C PF04426.7 EPX73254.1 - 0.0099 15.0 3.1 0.0099 15.0 2.2 3.1 3 0 0 3 3 3 1 Bul1 C terminus Reo_sigmaC PF04582.7 EPX73255.1 - 0.041 13.0 41.7 0.025 13.7 2.6 6.9 4 1 2 7 7 7 0 Reovirus sigma C capsid protein Gly_transf_sug PF04488.10 EPX73256.1 - 1.6e-16 60.5 0.0 3.7e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EPX73256.1 - 0.026 13.0 0.0 0.061 11.7 0.0 1.6 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain CNH PF00780.17 EPX73257.1 - 1.5e-73 247.6 0.3 2.9e-73 246.6 0.0 1.6 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.15 EPX73257.1 - 3.7e-36 124.6 0.2 6.2e-36 123.9 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EPX73257.1 - 7.9e-27 93.8 0.0 2.3e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.16 EPX73257.1 - 1.8e-14 53.2 0.0 3.2e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DEAD PF00270.24 EPX73258.1 - 2.2e-44 150.9 3.2 2.5e-44 150.7 0.6 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX73258.1 - 6e-27 93.3 0.5 3.2e-26 91.0 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX73258.1 - 0.00083 19.2 0.1 0.0025 17.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EPX73258.1 - 0.0014 18.2 0.3 0.0038 16.8 0.1 1.8 2 1 0 2 2 2 1 AAA domain Fanconi_A PF03511.9 EPX73258.1 - 0.0028 17.4 0.3 0.0053 16.5 0.2 1.5 1 0 0 1 1 1 1 Fanconi anaemia group A protein DUF1253 PF06862.7 EPX73258.1 - 0.0088 14.4 0.0 2.7 6.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_19 PF13245.1 EPX73258.1 - 0.036 13.8 1.6 0.069 12.9 0.1 2.2 2 1 0 3 3 3 0 Part of AAA domain UvrD-helicase PF00580.16 EPX73258.1 - 0.058 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.1 EPX73258.1 - 0.065 12.8 0.2 0.087 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 EPX73258.1 - 0.082 11.9 0.0 0.24 10.4 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 EPX73258.1 - 0.084 12.6 0.3 0.33 10.7 0.2 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 EPX73258.1 - 0.11 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Helicase Pkinase PF00069.20 EPX73260.1 - 8.2e-62 208.6 0.0 1.6e-61 207.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73260.1 - 7.5e-29 100.5 0.0 9.8e-28 96.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX73260.1 - 0.00021 20.3 0.0 0.48 9.3 0.0 3.2 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 EPX73260.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L7Ae PF01248.21 EPX73261.1 - 1.5e-24 85.2 0.0 2e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family APP_Cu_bd PF12924.2 EPX73261.1 - 0.15 12.6 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD DNA_binding_1 PF01035.15 EPX73262.1 - 4.4e-25 87.2 0.0 5.6e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain TFIIIC_sub6 PF10419.4 EPX73263.1 - 7.7e-12 44.4 0.1 1.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit UQ_con PF00179.21 EPX73264.1 - 4.4e-43 146.0 0.0 5e-43 145.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPX73264.1 - 0.00019 21.1 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B BSMAP PF12280.3 EPX73265.1 - 0.0024 17.8 3.5 0.0031 17.4 2.5 1.3 1 1 0 1 1 1 1 Brain specific membrane anchored protein HD-ZIP_N PF04618.7 EPX73265.1 - 0.016 15.7 5.2 0.032 14.7 3.6 1.6 1 1 0 1 1 1 0 HD-ZIP protein N terminus IPP-2 PF04979.9 EPX73265.1 - 0.066 13.4 11.4 0.092 12.9 7.9 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) Zip PF02535.17 EPX73265.1 - 0.11 11.4 1.4 0.12 11.3 1.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 EPX73265.1 - 0.17 11.7 7.7 0.18 11.7 5.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DHHW PF14286.1 EPX73265.1 - 0.24 10.6 5.2 0.3 10.3 3.6 1.0 1 0 0 1 1 1 0 DHHW protein Neur_chan_memb PF02932.11 EPX73265.1 - 0.26 11.1 4.2 0.28 11.0 2.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIF_alpha PF05793.7 EPX73265.1 - 0.34 9.2 18.0 0.38 9.0 12.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.12 EPX73265.1 - 0.9 8.2 4.1 1 8.0 2.8 1.1 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.11 EPX73265.1 - 1.5 8.2 6.7 1.8 7.9 4.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Hid1 PF12722.2 EPX73265.1 - 1.5 6.3 10.7 1.6 6.2 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2370 PF10176.4 EPX73265.1 - 3.8 6.7 5.5 4.1 6.6 3.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) Secretin_N_2 PF07655.8 EPX73265.1 - 3.9 7.9 7.4 6.3 7.2 5.1 1.4 1 1 0 1 1 1 0 Secretin N-terminal domain Ycf1 PF05758.7 EPX73265.1 - 4.3 4.9 11.1 5 4.7 7.7 1.0 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 EPX73265.1 - 4.6 6.5 19.5 5.7 6.2 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SNF2_N PF00176.18 EPX73266.1 - 2.4e-80 269.5 0.8 2.4e-80 269.5 0.5 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EPX73266.1 - 5.4e-20 71.0 0.9 5.4e-20 71.0 0.6 2.4 2 0 0 2 2 2 1 Bromodomain HSA PF07529.8 EPX73266.1 - 4.9e-17 61.4 12.4 4.9e-17 61.4 8.6 2.6 2 0 0 2 2 2 1 HSA Helicase_C PF00271.26 EPX73266.1 - 1e-15 57.3 0.3 8.7e-15 54.3 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EPX73266.1 - 5.3e-11 42.5 4.5 5.3e-11 42.5 3.1 3.3 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.10 EPX73266.1 - 2.1e-05 24.4 0.0 2.1e-05 24.4 0.0 4.1 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit Radical_SAM PF04055.16 EPX73267.1 - 5.8e-19 68.8 0.1 1.3e-18 67.7 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EPX73267.1 - 2.5e-13 49.8 0.0 8.2e-13 48.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPX73267.1 - 0.036 14.1 0.0 0.095 12.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPX73267.1 - 0.08 13.1 0.1 0.22 11.7 0.1 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain E1-E2_ATPase PF00122.15 EPX73268.1 - 1.2e-30 106.3 0.8 2.2e-30 105.3 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.3 EPX73268.1 - 3e-15 56.1 0.0 1.2e-14 54.2 0.0 2.1 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EPX73268.1 - 5.9e-12 46.1 0.0 1.3e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPX73268.1 - 1.6e-07 31.2 0.0 4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EPX73268.1 - 1.9e-05 25.1 0.0 0.00048 20.5 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPX73268.1 - 2.7e-05 23.5 0.0 6.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus WD40 PF00400.27 EPX73269.1 - 1.5e-32 110.2 10.5 1.3e-07 31.2 0.1 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EPX73269.1 - 1.3e-20 73.0 0.0 3.6e-20 71.6 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Apc4_WD40 PF12894.2 EPX73269.1 - 0.19 11.2 3.2 9.4 5.8 0.1 3.9 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain FUN14 PF04930.10 EPX73270.1 - 1.1e-18 67.3 0.1 1.4e-18 67.0 0.1 1.1 1 0 0 1 1 1 1 FUN14 family Pkinase PF00069.20 EPX73271.1 - 5e-64 215.9 0.0 1.3e-63 214.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73271.1 - 4e-28 98.2 0.0 6.5e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX73271.1 - 0.0084 15.0 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2521 PF10730.4 EPX73271.1 - 0.15 11.8 1.2 0.28 10.9 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2521) tRNA-synt_2b PF00587.20 EPX73272.1 - 2e-34 118.6 0.1 3.5e-34 117.8 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EPX73272.1 - 1.3e-26 92.7 6.0 1.3e-26 92.7 4.1 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 EPX73272.1 - 0.028 14.0 2.5 0.052 13.2 1.8 1.4 1 0 0 1 1 1 0 Mnd1 family Peroxin-3 PF04882.7 EPX73273.1 - 9.2e-16 57.5 7.7 2.2e-08 33.2 2.0 3.7 1 1 2 3 3 3 3 Peroxin-3 UreF PF01730.11 EPX73274.1 - 2.9e-13 50.1 0.0 4e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 UreF RE_LlaJI PF09563.5 EPX73275.1 - 0.093 11.4 0.3 0.14 10.7 0.2 1.2 1 0 0 1 1 1 0 LlaJI restriction endonuclease RhoGAP PF00620.22 EPX73276.1 - 3.8e-41 140.2 0.3 1e-40 138.8 0.2 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EPX73276.1 - 5.1e-17 61.6 21.0 5.4e-10 39.1 3.2 4.3 4 1 0 4 4 4 2 LIM domain C1_1 PF00130.17 EPX73276.1 - 0.00012 21.6 5.8 0.00012 21.6 4.0 4.5 3 2 0 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.26 EPX73277.1 - 0.0037 17.2 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Prp19 PF08606.6 EPX73278.1 - 1e-29 102.0 1.6 2e-29 101.1 1.1 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 EPX73278.1 - 0.00084 19.2 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 U-box domain BBS2_Mid PF14783.1 EPX73278.1 - 0.0015 18.2 0.0 0.045 13.5 0.0 2.5 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region DUF3312 PF11768.3 EPX73278.1 - 0.0061 14.8 0.0 0.0098 14.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) WD40 PF00400.27 EPX73278.1 - 0.0093 15.8 5.2 0.13 12.2 0.0 4.3 6 0 0 6 6 6 1 WD domain, G-beta repeat zf-Nse PF11789.3 EPX73278.1 - 0.015 14.8 0.0 0.059 12.8 0.0 2.1 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Spore_III_AB PF09548.5 EPX73278.1 - 0.28 10.9 1.1 0.47 10.1 0.8 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Nop25 PF09805.4 EPX73279.1 - 6e-26 91.1 29.8 6e-26 91.1 20.7 2.3 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) DUF3333 PF11812.3 EPX73279.1 - 0.0057 16.6 4.5 0.0098 15.8 3.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3333) PIG-S PF10510.4 EPX73279.1 - 2 6.9 10.6 2.4 6.7 7.3 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF2244 PF10003.4 EPX73279.1 - 2.9 7.2 8.1 0.45 9.8 0.1 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Med22 PF06179.7 EPX73280.1 - 7e-20 71.0 1.2 9.4e-20 70.6 0.8 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF2040 PF09745.4 EPX73281.1 - 8.6e-29 99.9 19.6 8.6e-29 99.9 13.6 3.4 2 2 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Enolase_N PF03952.11 EPX73281.1 - 0.18 11.7 3.8 2 8.3 0.1 2.8 2 1 1 3 3 3 0 Enolase, N-terminal domain EF-hand_1 PF00036.27 EPX73282.1 - 9.3e-15 52.7 0.0 0.00017 20.6 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EPX73282.1 - 6.5e-13 48.6 0.1 1.1e-08 35.0 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EPX73282.1 - 4.7e-12 44.7 0.0 0.00053 19.6 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.1 EPX73282.1 - 1.7e-10 40.6 0.0 0.00018 21.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EPX73282.1 - 1.6e-09 37.2 2.2 0.0045 16.5 0.0 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EPX73282.1 - 0.00016 20.8 0.2 0.21 11.0 0.0 2.8 2 0 0 2 2 2 2 EF hand Caleosin PF05042.8 EPX73282.1 - 0.089 12.3 0.0 0.52 9.8 0.0 2.0 2 1 0 2 2 2 0 Caleosin related protein DKCLD PF08068.7 EPX73283.1 - 1.3e-29 101.8 0.0 5.3e-29 99.9 0.0 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain PUA PF01472.15 EPX73283.1 - 2.9e-22 78.1 1.7 5.5e-22 77.2 1.2 1.5 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.13 EPX73283.1 - 5.8e-20 71.9 7.6 3.6e-19 69.3 0.1 3.7 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) RNase_H2-Ydr279 PF09468.5 EPX73283.1 - 0.019 14.2 21.3 0.029 13.5 14.8 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF1510 PF07423.6 EPX73283.1 - 0.055 12.8 23.2 0.075 12.3 16.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_polI_A34 PF08208.6 EPX73283.1 - 0.21 11.2 41.4 0.43 10.2 28.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.4 EPX73283.1 - 5 6.7 33.0 11 5.6 22.9 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CT47 PF15623.1 EPX73283.1 - 5.1 6.7 25.2 7.1 6.2 17.5 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 RR_TM4-6 PF06459.7 EPX73283.1 - 6.6 6.5 26.1 9.2 6.0 18.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 EPX73283.1 - 8.8 5.2 9.0 12 4.8 6.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_S9 PF00380.14 EPX73284.1 - 2.8e-36 124.4 0.4 3.1e-36 124.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Smr PF01713.16 EPX73284.1 - 0.0075 16.4 0.3 0.6 10.3 0.1 2.2 1 1 1 2 2 2 2 Smr domain PAAR_motif PF05488.8 EPX73284.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 1 0 1 1 1 0 PAAR motif EF1G PF00647.14 EPX73285.1 - 7.6e-43 144.5 0.0 1.5e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EPX73285.1 - 2.9e-12 46.4 0.0 6.3e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPX73285.1 - 5.1e-08 32.9 0.0 1.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPX73285.1 - 1.6e-07 31.1 0.0 3.5e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPX73285.1 - 0.00033 21.0 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPX73285.1 - 0.00041 20.5 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Pyr_redox_2 PF07992.9 EPX73286.1 - 1.9e-30 106.2 0.0 1.3e-29 103.5 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPX73286.1 - 8.3e-17 61.3 1.2 6.2e-11 42.5 0.1 3.8 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EPX73286.1 - 4.4e-12 45.4 0.0 9.2e-12 44.3 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EPX73286.1 - 3.8e-08 33.6 0.0 0.00011 22.3 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPX73286.1 - 9.3e-07 28.0 0.1 0.56 9.0 0.0 4.5 3 1 2 5 5 5 2 FAD dependent oxidoreductase Reductase_C PF14759.1 EPX73286.1 - 5.1e-05 23.4 0.0 0.00014 22.0 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 EPX73286.1 - 0.00018 20.5 0.0 0.41 9.4 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EPX73286.1 - 0.0016 18.4 0.2 0.068 13.2 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Rieske_2 PF13806.1 EPX73286.1 - 0.0024 17.5 0.0 0.0071 16.0 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain FAD_binding_2 PF00890.19 EPX73286.1 - 0.0034 16.2 0.3 0.13 11.1 0.0 2.8 2 1 2 4 4 4 1 FAD binding domain NAD_binding_9 PF13454.1 EPX73286.1 - 0.0044 16.8 0.0 8.6 6.1 0.0 3.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EPX73286.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain tRNA-synt_1 PF00133.17 EPX73287.1 - 1.8e-45 155.0 0.0 4.6e-34 117.4 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EPX73287.1 - 5e-20 71.5 0.0 3.3e-11 42.4 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EPX73287.1 - 2.7e-15 56.4 0.4 7.3e-15 55.0 0.1 1.8 1 1 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EPX73287.1 - 9.2e-10 38.1 0.0 2.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF383 PF04063.9 EPX73288.1 - 1.1e-70 237.1 0.1 1.1e-70 237.1 0.1 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EPX73288.1 - 2.2e-23 81.5 2.5 4.1e-23 80.7 0.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF384) GlgS PF08971.6 EPX73288.1 - 0.062 13.2 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycogen synthesis protein Y_phosphatase PF00102.22 EPX73289.1 - 8.5e-66 221.6 0.1 1.4e-65 220.9 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EPX73289.1 - 0.00021 21.3 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EPX73289.1 - 0.00097 18.7 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EPX73289.1 - 0.0028 17.9 0.0 0.022 15.1 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 EPX73289.1 - 0.007 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family RabGAP-TBC PF00566.13 EPX73290.1 - 8.3e-40 136.5 0.1 8.3e-40 136.5 0.1 4.1 4 1 1 5 5 5 1 Rab-GTPase-TBC domain DUF3496 PF12001.3 EPX73290.1 - 0.0038 17.4 1.7 0.0038 17.4 1.1 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3496) ALMT PF11744.3 EPX73291.1 - 7e-23 80.9 20.3 2.5e-18 65.9 7.4 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.1 EPX73291.1 - 1e-16 61.0 28.5 2.9e-14 53.0 9.4 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like DUF2422 PF10337.4 EPX73291.1 - 5.8e-16 58.3 10.9 4.5e-08 32.3 0.2 3.3 2 1 1 3 3 3 3 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EPX73291.1 - 5.1e-11 42.6 1.3 6.5e-11 42.2 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC PF04632.7 EPX73291.1 - 4.3e-09 35.3 10.7 4.3e-09 35.3 7.4 1.5 2 0 0 2 2 2 1 Fusaric acid resistance protein family DUF939 PF06081.6 EPX73291.1 - 3.5e-06 26.9 5.8 3.5e-06 26.9 4.0 2.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF939) Aldo_ket_red PF00248.16 EPX73292.1 - 8.8e-56 188.7 0.0 1e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3272 PF11676.3 EPX73293.1 - 0.18 11.8 2.2 0.24 11.4 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3272) His_Phos_1 PF00300.17 EPX73294.1 - 1e-44 152.3 0.0 1.2e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ADH_zinc_N PF00107.21 EPX73295.1 - 3.1e-15 55.8 0.0 5.4e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPX73295.1 - 0.035 13.8 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain E1_dh PF00676.15 EPX73296.1 - 1.4e-119 398.3 0.0 1.6e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EPX73296.1 - 0.00071 18.5 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Pinin_SDK_memA PF04696.8 EPX73297.1 - 1.2e-19 70.1 19.6 1.2e-19 70.1 13.6 1.6 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Apis_Csd PF11671.3 EPX73297.1 - 1.2 8.9 5.0 2.1 8.1 3.4 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein Caldesmon PF02029.10 EPX73297.1 - 2.8 6.2 27.2 3.4 5.9 18.9 1.1 1 0 0 1 1 1 0 Caldesmon Sec7 PF01369.15 EPX73298.1 - 2.4e-37 128.4 0.2 4.5e-37 127.5 0.1 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 EPX73298.1 - 2e-11 43.9 2.2 4e-11 43.0 0.1 2.5 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EPX73298.1 - 8.4e-06 25.9 0.0 2.4e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Yippee-Mis18 PF03226.9 EPX73299.1 - 2.1e-14 53.3 0.8 2.7e-14 52.9 0.6 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.4 EPX73299.1 - 0.034 14.1 0.4 0.27 11.2 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF543 PF04418.7 EPX73300.1 - 9.1e-25 86.4 0.2 1.1e-24 86.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Aph-1 PF06105.7 EPX73300.1 - 0.072 12.3 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 Aph-1 protein Y_phosphatase PF00102.22 EPX73302.1 - 1.3e-57 194.8 0.1 1.8e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EPX73302.1 - 9.4e-07 29.1 0.0 8.5e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 EPX73302.1 - 0.00023 20.7 0.0 0.00065 19.2 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EPX73302.1 - 0.0027 17.7 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EPX73302.1 - 0.0055 16.9 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Peroxin-22 PF12827.2 EPX73303.1 - 0.0066 16.1 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family DUF3976 PF13121.1 EPX73303.1 - 0.14 12.0 1.5 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3976) PAP_assoc PF03828.14 EPX73304.1 - 2.1e-18 65.9 0.0 4.2e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPX73304.1 - 0.00022 21.4 0.0 0.00051 20.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 EPX73304.1 - 0.00027 19.8 0.0 0.36 9.5 0.0 2.3 2 0 0 2 2 2 2 Poly(A) polymerase central domain DUF913 PF06025.7 EPX73305.1 - 4.3e-102 341.7 5.2 5.2e-95 318.3 1.4 3.3 1 1 1 2 2 2 2 Domain of Unknown Function (DUF913) HECT PF00632.20 EPX73305.1 - 1.8e-94 316.4 0.0 4.3e-94 315.2 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EPX73305.1 - 7.9e-58 196.2 7.9 7.9e-58 196.2 5.4 3.5 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EPX73305.1 - 6.4e-14 51.7 4.9 6.4e-14 51.7 3.4 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) Ribosomal_S4 PF00163.14 EPX73306.1 - 2.6e-16 59.7 1.2 7e-16 58.3 0.8 1.8 3 0 0 3 3 3 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EPX73306.1 - 3.6e-13 48.7 0.0 9.1e-13 47.4 0.0 1.7 2 0 0 2 2 2 1 S4 domain Ctf8 PF09696.5 EPX73307.1 - 4.9e-18 65.0 0.2 1.2e-17 63.8 0.1 1.6 1 1 0 1 1 1 1 Ctf8 Vps8 PF12816.2 EPX73307.1 - 0.069 12.3 0.0 0.071 12.3 0.0 1.1 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 RAI1 PF08652.6 EPX73308.1 - 6.4e-23 80.3 0.1 4.2e-22 77.6 0.1 2.2 1 1 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Aminotran_3 PF00202.16 EPX73309.1 - 2.4e-85 286.3 0.0 2.8e-85 286.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EPX73309.1 - 0.047 12.6 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF1770 PF08589.5 EPX73310.1 - 8.8e-13 48.7 3.6 3.5e-12 46.7 2.4 2.0 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) SMC_N PF02463.14 EPX73311.1 - 1.5e-22 79.8 9.5 1.7e-21 76.4 6.6 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPX73311.1 - 6.9e-19 68.9 0.1 6.9e-19 68.9 0.0 4.7 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EPX73311.1 - 6e-08 33.0 2.4 6.9e-06 26.2 0.8 3.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPX73311.1 - 0.00062 19.2 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ndufs5 PF10200.4 EPX73311.1 - 0.023 14.6 1.5 0.077 12.9 0.0 2.7 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa ABC_tran PF00005.22 EPX73311.1 - 0.044 14.0 0.0 0.044 14.0 0.0 3.7 3 2 0 3 3 3 0 ABC transporter DASH_Dad3 PF08656.5 EPX73312.1 - 9.5e-23 79.7 1.5 1.1e-22 79.5 1.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.20 EPX73313.1 - 2.1e-64 217.1 0.1 6.7e-64 215.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73313.1 - 1.1e-29 103.2 0.0 2e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EPX73313.1 - 7.7e-11 41.9 0.1 2.2e-10 40.4 0.1 1.9 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EPX73313.1 - 1.1e-05 24.5 0.0 1.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPX73313.1 - 0.0099 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MSC PF09402.5 EPX73315.1 - 1.1e-33 116.4 7.8 1.6e-22 79.6 0.6 2.2 2 0 0 2 2 2 2 Man1-Src1p-C-terminal domain HeH PF12949.2 EPX73315.1 - 1.5e-14 53.2 0.1 4e-14 51.8 0.1 1.8 1 0 0 1 1 1 1 HeH/LEM domain MUG2_C PF08593.5 EPX73316.1 - 0.024 14.8 0.2 0.066 13.4 0.1 1.7 1 0 0 1 1 1 0 Meiotically up-regulated glycoproteins C-terminal NAD_binding_2 PF03446.10 EPX73316.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-CCCH PF00642.19 EPX73316.1 - 3.1 7.5 8.2 15 5.3 0.3 3.3 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MFS_1 PF07690.11 EPX73317.1 - 6.2e-21 74.4 31.8 4.5e-20 71.6 12.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily FhuF_C PF11575.3 EPX73317.1 - 0.037 13.6 0.3 0.037 13.6 0.2 2.1 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Glyco_hydro_71 PF03659.9 EPX73319.1 - 5e-116 387.3 6.8 5.7e-116 387.1 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 NUDIX PF00293.23 EPX73320.1 - 1.2e-15 57.3 0.0 2e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DBC1 PF14443.1 EPX73320.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 DBC1 VTC PF09359.5 EPX73321.1 - 1.2e-79 267.3 0.1 1.7e-79 266.7 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EPX73321.1 - 8.8e-17 61.7 13.7 2.7e-08 33.9 0.9 3.9 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EPX73321.1 - 9.6e-10 38.5 1.2 9.6e-10 38.5 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SWIRM PF04433.12 EPX73322.1 - 6.3e-13 48.6 0.0 1.3e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Rad17 PF03215.10 EPX73323.1 - 1.6e-109 366.9 5.4 2e-109 366.6 3.7 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EPX73323.1 - 2.8e-09 37.2 0.1 2e-08 34.4 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPX73323.1 - 1.6e-06 28.2 0.0 9e-06 25.8 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EPX73323.1 - 7e-05 22.7 0.1 0.00047 20.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPX73323.1 - 0.00019 21.1 0.0 0.00053 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EPX73323.1 - 0.00023 21.4 0.1 0.0013 19.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPX73323.1 - 0.00027 20.9 0.1 0.00088 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EPX73323.1 - 0.0003 20.4 0.0 0.00079 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EPX73323.1 - 0.00033 21.4 0.0 0.0013 19.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPX73323.1 - 0.00034 20.6 0.0 0.00063 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPX73323.1 - 0.00043 19.4 0.0 0.00078 18.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EPX73323.1 - 0.0017 18.5 0.0 0.013 15.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EPX73323.1 - 0.0025 17.6 0.0 0.0081 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPX73323.1 - 0.0059 15.7 0.0 0.016 14.3 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin Viral_helicase1 PF01443.13 EPX73323.1 - 0.0068 15.9 0.0 0.051 13.0 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 EPX73323.1 - 0.008 15.3 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EPX73323.1 - 0.011 16.0 1.5 0.072 13.3 0.0 3.1 3 2 0 3 3 3 0 ABC transporter UPF0079 PF02367.12 EPX73323.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EPX73323.1 - 0.045 13.4 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain T2SE PF00437.15 EPX73323.1 - 0.048 12.5 0.0 0.099 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.1 EPX73323.1 - 0.054 13.0 0.8 8.5 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EPX73323.1 - 0.1 12.3 0.1 0.8 9.3 0.0 2.4 3 0 0 3 3 3 0 NTPase AAA_11 PF13086.1 EPX73323.1 - 0.24 10.9 10.7 0.96 8.9 7.4 2.2 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EPX73324.1 - 7.5e-70 234.7 0.0 1.1e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPX73324.1 - 8.5e-26 90.6 0.0 1.9e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPX73324.1 - 4.9e-17 61.9 1.0 1.4e-16 60.3 0.7 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EPX73324.1 - 0.03 14.1 0.5 0.13 12.1 0.1 2.1 1 1 1 2 2 2 0 HAS barrel domain DPPIV_N PF00930.16 EPX73325.1 - 2e-55 187.8 0.2 2.6e-55 187.4 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EPX73325.1 - 1.5e-27 96.1 0.0 2.7e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPX73325.1 - 5.9e-06 26.1 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EPX73325.1 - 0.0028 16.9 0.0 0.015 14.5 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EPX73325.1 - 0.0074 15.7 0.9 0.23 10.8 0.1 2.5 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EPX73325.1 - 0.02 14.5 0.0 0.18 11.4 0.0 2.3 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.2 EPX73325.1 - 0.056 13.3 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family SH3_1 PF00018.23 EPX73326.1 - 1.3e-32 110.9 3.1 1.3e-15 56.4 0.1 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EPX73326.1 - 4.3e-31 106.2 5.1 2.5e-15 55.7 0.2 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 EPX73326.1 - 1.5e-27 94.8 0.8 5.9e-12 44.8 0.0 3.4 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 EPX73326.1 - 2.4e-11 43.6 0.0 4.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1505 PF07403.6 EPX73328.1 - 0.094 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) Zn_clus PF00172.13 EPX73329.1 - 1.1e-07 31.5 9.9 2e-07 30.8 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDZ PF00595.19 EPX73330.1 - 2.4e-05 24.4 0.0 4.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EPX73330.1 - 0.00022 21.0 0.1 0.00066 19.5 0.0 1.7 1 1 0 1 1 1 1 PDZ domain DUF3276 PF11680.3 EPX73330.1 - 0.0024 17.6 0.3 0.004 16.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3276) Cauli_DNA-bind PF03310.8 EPX73330.1 - 0.071 12.9 0.4 0.12 12.1 0.3 1.4 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein Peptidase_M26_C PF07580.9 EPX73330.1 - 0.17 10.1 1.1 0.2 9.8 0.8 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region SNF2_N PF00176.18 EPX73331.1 - 6.6e-72 241.8 0.9 1.6e-71 240.5 0.7 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPX73331.1 - 9.7e-15 54.1 0.1 2.4e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 EPX73331.1 - 4e-06 26.5 0.8 4e-06 26.5 0.5 3.3 1 1 2 3 3 3 1 HSA DEAD PF00270.24 EPX73331.1 - 1.8e-05 24.2 0.0 5.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Membr_traf_MHD PF10540.4 EPX73332.1 - 8.4e-27 93.6 0.1 3e-26 91.8 0.1 2.1 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EPX73332.1 - 1.8e-06 27.6 0.0 5.2e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 C2 domain APS-reductase_C PF12139.3 EPX73332.1 - 0.078 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit Csm1 PF12539.3 EPX73333.1 - 1.8e-15 57.1 0.2 4.5e-15 55.8 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 HlyD_2 PF12700.2 EPX73333.1 - 0.0068 15.6 1.8 0.011 14.8 1.2 1.3 1 0 0 1 1 1 1 HlyD family secretion protein THOC7 PF05615.8 EPX73333.1 - 0.98 9.6 11.1 1.8 8.8 5.3 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 VPS11_C PF12451.3 EPX73333.1 - 1.1 9.2 4.6 0.27 11.1 0.5 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal V_ATPase_I PF01496.14 EPX73333.1 - 6.2 4.5 11.1 7.7 4.2 7.7 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family UQ_con PF00179.21 EPX73334.1 - 5.1e-47 158.8 0.0 5.8e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPX73334.1 - 0.00039 20.1 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EPX73334.1 - 0.0062 16.2 0.1 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EPX73334.1 - 0.0074 16.1 0.1 0.011 15.6 0.1 1.6 1 1 0 1 1 1 1 RWD domain WD40 PF00400.27 EPX73335.1 - 1e-09 37.8 17.6 6.9e-05 22.5 0.4 5.9 6 1 0 6 6 6 4 WD domain, G-beta repeat NAD4L PF06235.6 EPX73335.1 - 0.066 12.9 0.2 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 4L (NAD4L) zf-RING_2 PF13639.1 EPX73335.1 - 2.4 8.0 11.9 0.38 10.6 5.3 1.9 2 0 0 2 2 2 0 Ring finger domain SRF-TF PF00319.13 EPX73336.1 - 2.3e-17 61.9 0.0 4.9e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) vATP-synt_E PF01991.13 EPX73337.1 - 3.5e-59 199.4 15.9 4.3e-59 199.1 11.0 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit TF_AP-2 PF03299.9 EPX73337.1 - 0.092 12.2 6.4 0.072 12.6 2.2 2.0 1 1 1 2 2 2 0 Transcription factor AP-2 IncA PF04156.9 EPX73337.1 - 5.8 6.4 12.5 2.5 7.6 1.2 2.2 1 1 1 2 2 2 0 IncA protein Nse5 PF08691.5 EPX73338.1 - 5.8e-10 38.2 16.8 6.8e-09 34.7 11.6 2.1 1 1 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Y_phosphatase PF00102.22 EPX73339.1 - 7.5e-60 202.1 0.2 9.1e-60 201.9 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EPX73339.1 - 4.5e-06 26.7 0.0 9.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EPX73339.1 - 0.00033 20.2 0.3 0.00088 18.8 0.0 1.7 1 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EPX73339.1 - 0.0012 19.1 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.9 EPX73339.1 - 0.0049 15.6 0.0 0.0073 15.1 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain VanZ PF04892.7 EPX73340.1 - 5.7e-16 58.6 8.2 1.2e-15 57.6 5.7 1.5 1 1 0 1 1 1 1 VanZ like family TauE PF01925.14 EPX73340.1 - 0.049 13.0 5.5 0.032 13.6 2.8 1.4 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE CbiM PF01891.11 EPX73340.1 - 0.17 11.4 6.3 0.21 11.1 4.4 1.1 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region GtrA PF04138.9 EPX73340.1 - 0.52 10.2 6.3 1.7 8.6 4.2 1.9 1 1 0 1 1 1 0 GtrA-like protein DUF751 PF05421.6 EPX73340.1 - 0.53 10.5 5.3 2.4 8.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF751) Snurportin1 PF11538.3 EPX73340.1 - 0.58 9.9 3.0 0.27 11.0 0.3 1.7 2 0 0 2 2 2 0 Snurportin1 7TMR-DISM_7TM PF07695.6 EPX73340.1 - 1.2 8.7 11.7 3.7 7.1 8.3 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling Sec7 PF01369.15 EPX73341.1 - 5.8e-36 123.9 4.5 8.4e-36 123.4 2.4 1.8 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 EPX73341.1 - 1.3e-09 38.1 0.1 6.3e-09 36.0 0.0 2.2 3 0 0 3 3 3 1 Pleckstrin homology domain 2Fe-2S_thioredx PF01257.14 EPX73342.1 - 4e-24 84.8 0.0 6.2e-24 84.2 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Glyco_hydro_72 PF03198.9 EPX73343.1 - 4.3e-138 459.5 4.0 5.4e-138 459.2 2.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EPX73343.1 - 1.5e-05 24.3 0.4 0.00014 21.1 0.3 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) WD40 PF00400.27 EPX73344.1 - 6e-11 41.7 0.5 0.006 16.4 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Lactonase PF10282.4 EPX73344.1 - 0.00053 19.1 0.0 0.28 10.2 0.0 2.2 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller BBS2_Mid PF14783.1 EPX73344.1 - 0.035 13.8 0.1 5.2 6.8 0.0 3.2 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nop16 PF09420.5 EPX73345.1 - 1.7e-38 132.3 8.3 2e-38 132.0 5.8 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 ELFV_dehydrog_N PF02812.13 EPX73345.1 - 0.1 12.1 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Sel1 PF08238.7 EPX73346.1 - 4e-19 68.6 16.2 4.4e-05 23.9 0.1 6.5 6 0 0 6 6 6 5 Sel1 repeat TPR_2 PF07719.12 EPX73346.1 - 1.7e-08 33.7 0.7 4.3e-05 23.1 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPX73346.1 - 3.1e-08 32.8 1.0 7.3e-05 22.2 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPX73346.1 - 2.6e-06 26.8 5.5 0.0002 20.8 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPX73346.1 - 5.6e-05 22.9 1.9 0.0039 17.0 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPX73346.1 - 0.00021 21.5 1.0 0.073 13.5 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPX73346.1 - 0.00032 20.2 1.5 0.0019 17.8 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPX73346.1 - 0.00074 19.1 5.8 0.014 15.0 0.1 3.4 2 1 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 EPX73346.1 - 0.00076 20.0 4.6 0.14 12.8 0.2 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPX73346.1 - 0.0031 17.5 3.8 1.8 8.9 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPX73346.1 - 0.0064 17.0 0.8 0.14 12.8 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 EPX73346.1 - 0.052 13.4 3.0 7.7 6.4 0.1 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EPX73346.1 - 0.61 10.1 4.2 0.76 9.8 0.1 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat RRM_6 PF14259.1 EPX73347.1 - 7.4e-15 54.6 0.1 4.9e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX73347.1 - 8.1e-13 47.8 0.1 6e-05 22.6 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX73347.1 - 9e-07 28.6 0.1 1e-05 25.2 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1985 PF09331.6 EPX73347.1 - 0.012 15.3 1.7 0.11 12.2 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) RRM_3 PF08777.6 EPX73347.1 - 0.044 13.6 3.2 7.4 6.4 0.0 3.3 2 1 0 3 3 3 0 RNA binding motif GIDA PF01134.17 EPX73347.1 - 0.048 12.5 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A SET_assoc PF11767.3 EPX73347.1 - 0.13 11.6 0.1 0.86 8.9 0.0 2.2 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Ras PF00071.17 EPX73348.1 - 1.2e-47 161.3 0.0 1.4e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX73348.1 - 9.1e-15 55.2 0.0 1.8e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX73348.1 - 8.4e-11 41.4 0.0 1.1e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPX73348.1 - 0.00015 21.0 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 EPX73348.1 - 0.00023 21.3 0.1 0.0018 18.4 0.0 2.1 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.15 EPX73348.1 - 0.023 13.3 1.7 0.97 8.0 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 EPX73348.1 - 0.027 13.7 0.1 0.047 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EPX73348.1 - 0.047 13.8 0.1 0.26 11.4 0.1 2.0 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EPX73348.1 - 0.075 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EPX73348.1 - 0.16 11.0 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 KaiC SAM_2 PF07647.12 EPX73349.1 - 3.5e-15 55.5 0.0 6.7e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EPX73349.1 - 8.6e-11 41.8 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EPX73349.1 - 1.3e-10 41.5 0.0 3.4e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EPX73349.1 - 1.7e-10 40.9 0.0 5.6e-10 39.3 0.0 2.0 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 EPX73349.1 - 1.9e-10 39.9 0.1 4.9e-10 38.6 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPX73349.1 - 1.5e-08 34.0 0.0 2.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 EPX73349.1 - 0.0021 18.1 0.1 0.026 14.5 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.12 EPX73349.1 - 0.003 17.0 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain V-ATPase_G PF03179.10 EPX73350.1 - 4.4e-30 104.0 16.6 5e-30 103.9 11.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EPX73350.1 - 0.0023 17.7 18.9 0.055 13.2 7.4 2.1 1 1 1 2 2 2 2 ATP synthase B/B' CF(0) DUF3375 PF11855.3 EPX73350.1 - 0.011 14.5 4.9 0.012 14.4 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) AIP3 PF03915.8 EPX73350.1 - 0.018 13.9 9.1 0.019 13.9 6.3 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 DUF3552 PF12072.3 EPX73350.1 - 0.024 13.8 19.5 0.062 12.5 6.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Nop25 PF09805.4 EPX73350.1 - 0.025 14.6 13.3 0.032 14.2 9.2 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) GA PF01468.12 EPX73350.1 - 0.026 14.6 1.3 0.026 14.6 0.9 2.5 3 0 0 3 3 3 0 GA module Gp58 PF07902.6 EPX73350.1 - 0.05 11.8 4.7 0.056 11.6 3.3 1.0 1 0 0 1 1 1 0 gp58-like protein DUF2813 PF11398.3 EPX73350.1 - 0.14 11.1 2.1 0.17 10.9 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Peptidase_S46 PF10459.4 EPX73350.1 - 0.16 10.3 7.4 0.18 10.1 5.1 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF3584 PF12128.3 EPX73350.1 - 0.32 8.2 11.0 0.36 8.1 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HSP70 PF00012.15 EPX73350.1 - 0.51 8.1 10.6 0.6 7.9 7.4 1.0 1 0 0 1 1 1 0 Hsp70 protein HrpE PF06188.7 EPX73350.1 - 0.56 9.9 8.4 1 9.0 5.8 1.4 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E SpoVR PF04293.8 EPX73350.1 - 0.63 8.3 7.3 0.71 8.1 5.1 1.0 1 0 0 1 1 1 0 SpoVR like protein PEP-utilisers_N PF05524.8 EPX73350.1 - 0.64 9.8 9.4 9.4 6.0 6.5 2.1 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal vATP-synt_E PF01991.13 EPX73350.1 - 2.8 7.1 21.2 2.3 7.4 5.4 2.1 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit KfrA_N PF11740.3 EPX73350.1 - 4 7.9 10.1 1.8 9.0 4.9 1.8 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Atg14 PF10186.4 EPX73350.1 - 4.5 6.1 10.2 5.2 5.9 7.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF883 PF05957.8 EPX73350.1 - 5 7.5 10.1 25 5.3 2.1 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Apc9 PF12856.2 EPX73350.1 - 5 7.2 8.9 91 3.2 6.2 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 9 Seryl_tRNA_N PF02403.17 EPX73350.1 - 7.5 6.6 12.2 23 5.0 8.5 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SseC PF04888.7 EPX73350.1 - 8.7 5.5 13.8 0.25 10.6 3.8 2.0 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family RNA_pol_A_bac PF01000.21 EPX73352.1 - 3e-28 98.1 0.0 7.6e-28 96.9 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EPX73352.1 - 3.7e-13 48.3 0.0 5.2e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain UDPGP PF01704.13 EPX73353.1 - 1.1e-44 152.6 0.0 1.4e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EPX73353.1 - 0.0052 16.8 0.0 0.013 15.6 0.0 1.6 2 0 0 2 2 2 1 MobA-like NTP transferase domain TIM21 PF08294.6 EPX73354.1 - 2.1e-38 131.2 0.0 2.7e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 TIM21 Cyt-b5 PF00173.23 EPX73355.1 - 2.4e-21 75.3 0.1 3.3e-21 74.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LysM PF01476.15 EPX73355.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 LysM domain LisH PF08513.6 EPX73356.1 - 2e-10 40.0 0.5 3.9e-10 39.1 0.3 1.5 1 0 0 1 1 1 1 LisH HSP20 PF00011.16 EPX73357.1 - 2.3e-21 75.5 0.9 2.8e-21 75.3 0.6 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PIH1 PF08190.7 EPX73357.1 - 0.007 15.8 0.0 0.0077 15.7 0.0 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 CS PF04969.11 EPX73357.1 - 0.043 14.3 0.4 0.1 13.1 0.2 1.8 1 1 1 2 2 2 0 CS domain DUF4097 PF13349.1 EPX73357.1 - 0.049 13.1 0.1 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) OmpA PF00691.15 EPX73357.1 - 0.088 13.2 0.1 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 OmpA family DUF2254 PF10011.4 EPX73358.1 - 3.5 5.9 5.4 4.8 5.5 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) zf-DHHC PF01529.15 EPX73358.1 - 6 6.2 5.8 9.4 5.5 4.0 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase WTF PF03303.8 EPX73359.1 - 3.8e-05 23.2 0.3 5.9e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 WTF protein EcsB PF05975.7 EPX73359.1 - 1.5 7.2 6.7 2 6.8 4.7 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Baculo_p74 PF04583.7 EPX73359.1 - 2.3 7.3 6.9 0.18 10.9 0.4 1.9 1 1 1 2 2 2 0 Baculoviridae p74 conserved region WD40 PF00400.27 EPX73361.1 - 2e-43 144.7 7.0 5.5e-08 32.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EPX73361.1 - 0.00011 20.4 2.7 0.0041 15.3 1.9 2.1 1 1 0 1 1 1 1 Nucleoporin Nup120/160 RRM_1 PF00076.17 EPX73362.1 - 3.2e-25 87.5 0.0 3.3e-10 39.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX73362.1 - 1.5e-13 50.5 0.0 0.0022 17.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX73362.1 - 1.5e-07 31.1 0.0 0.046 13.5 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EPX73362.1 - 7.1e-07 28.8 0.0 0.00063 19.4 0.0 2.8 3 0 0 3 3 3 2 Limkain b1 Calcipressin PF04847.7 EPX73362.1 - 0.00052 19.6 0.0 0.0096 15.5 0.0 2.2 2 0 0 2 2 2 1 Calcipressin Nup35_RRM_2 PF14605.1 EPX73362.1 - 0.13 12.0 0.0 0.48 10.2 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Fungal_trans PF04082.13 EPX73363.1 - 1.3e-20 73.4 4.5 2e-20 72.8 2.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX73363.1 - 2.2e-08 33.8 10.1 5.3e-08 32.6 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt4 PF06093.8 EPX73363.1 - 2.3 8.1 6.1 18 5.2 2.3 2.8 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger AA_permease PF00324.16 EPX73364.1 - 1e-122 409.9 43.3 1.3e-122 409.6 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPX73364.1 - 7.3e-33 113.7 44.8 9.8e-33 113.3 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease SPC25 PF06703.6 EPX73365.1 - 0.024 14.2 0.3 0.062 12.8 0.2 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Abhydrolase_3 PF07859.8 EPX73366.1 - 3.7e-55 186.7 0.0 4.6e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EPX73366.1 - 1.5e-05 23.8 0.0 2.1e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EPX73366.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPX73366.1 - 0.009 15.2 0.0 0.032 13.4 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 EPX73366.1 - 0.045 12.4 0.3 3.7 6.1 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_2 PF02230.11 EPX73366.1 - 0.13 11.6 0.0 0.75 9.1 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FBPase PF00316.15 EPX73367.1 - 4.3e-120 400.4 0.0 4.9e-120 400.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EPX73367.1 - 0.0057 15.9 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family PhzC-PhzF PF02567.11 EPX73368.1 - 1.9e-62 211.0 0.0 2.2e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 EPX73368.1 - 2.2e-05 23.4 0.0 3.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Proline racemase DUF1410 PF07198.6 EPX73369.1 - 0.24 11.7 1.9 0.37 11.1 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1410) DUF3808 PF10300.4 EPX73370.1 - 7.4e-76 255.5 2.1 9.1e-76 255.2 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Dynamitin PF04912.9 EPX73370.1 - 0.0065 15.3 0.3 0.01 14.6 0.2 1.3 1 0 0 1 1 1 1 Dynamitin Mer2 PF09074.5 EPX73370.1 - 0.02 14.8 2.4 0.5 10.2 0.0 3.3 3 0 0 3 3 3 0 Mer2 XendoU PF09412.5 EPX73370.1 - 0.037 13.0 0.0 0.07 12.1 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease XendoU Phage_glycop_gL PF11108.3 EPX73370.1 - 0.21 11.5 1.7 0.65 9.9 0.0 2.7 3 0 0 3 3 3 0 Viral glycoprotein L Glyco_transf_34 PF05637.7 EPX73371.1 - 3.3e-74 249.4 0.4 4.1e-74 249.0 0.3 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 EPX73371.1 - 0.0097 15.7 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase TPP_enzyme_N PF02776.13 EPX73372.1 - 2.8e-39 134.3 0.1 1.1e-36 125.8 0.1 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EPX73372.1 - 5.6e-25 87.6 3.1 2.4e-23 82.4 0.0 3.2 4 0 0 4 4 4 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPX73372.1 - 6.3e-20 71.3 0.0 2.5e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 EPX73372.1 - 8.5e-06 25.4 0.2 2.4e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit XH PF03469.9 EPX73372.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 XH domain OPT PF03169.10 EPX73373.1 - 3.5e-201 669.8 44.2 4.1e-201 669.6 30.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TauD PF02668.11 EPX73374.1 - 4.1e-45 154.4 0.8 5.6e-45 154.0 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lipid_DES PF08557.5 EPX73374.1 - 0.032 13.4 0.2 0.075 12.2 0.1 1.7 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) MFS_1 PF07690.11 EPX73375.1 - 3e-26 91.9 40.8 3e-26 91.9 28.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX73375.1 - 3e-08 32.6 42.8 6.5e-08 31.5 29.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Arginase PF00491.16 EPX73376.1 - 2e-90 302.8 0.0 2.5e-90 302.5 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EPX73376.1 - 0.005 17.0 0.1 0.0088 16.2 0.1 1.3 1 0 0 1 1 1 1 UPF0489 domain NAD_binding_10 PF13460.1 EPX73377.1 - 5.5e-22 78.6 0.0 6.9e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPX73377.1 - 2e-06 27.3 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPX73377.1 - 0.00034 19.6 0.0 0.00045 19.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EPX73377.1 - 0.0019 17.4 0.0 0.0027 17.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family MFS_1 PF07690.11 EPX73378.1 - 1.1e-44 152.6 29.1 1.5e-44 152.1 20.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.11 EPX73378.1 - 0.045 12.4 9.2 0.11 11.2 6.4 1.6 1 1 0 1 1 1 0 BT1 family MUG2_C PF08593.5 EPX73379.1 - 3.4e-07 30.3 0.0 6.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal GalP_UDP_tr_C PF02744.12 EPX73380.1 - 3.1e-62 209.0 0.3 8.2e-62 207.6 0.2 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.17 EPX73380.1 - 3.2e-61 206.5 1.1 4.2e-61 206.1 0.4 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain DcpS_C PF11969.3 EPX73380.1 - 0.002 18.3 1.0 0.0038 17.4 0.2 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EPX73380.1 - 0.0023 18.4 0.1 0.013 16.0 0.0 2.1 2 0 0 2 2 2 1 HIT domain Oxidored_FMN PF00724.15 EPX73381.1 - 1.7e-100 336.3 0.0 3.5e-76 256.4 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 EPX73383.1 - 1.1e-105 353.4 0.0 1.2e-105 353.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pentaxin PF00354.12 EPX73383.1 - 0.089 12.2 0.0 0.83 9.0 0.0 2.1 2 0 0 2 2 2 0 Pentaxin family Asp PF00026.18 EPX73384.1 - 1.1e-42 146.3 3.7 1.3e-42 146.1 2.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPX73384.1 - 8.8e-12 45.2 0.0 1.9e-10 40.9 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EPX73384.1 - 4.9e-06 26.9 0.2 0.09 13.2 0.0 3.2 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 EPX73384.1 - 1.3e-05 24.8 0.0 0.003 17.3 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 EPX73384.1 - 0.00013 21.8 0.1 0.67 9.9 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease GPI-anchored PF10342.4 EPX73385.1 - 2.3e-11 43.9 0.1 2.8e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Sugar_tr PF00083.19 EPX73386.1 - 1.1e-26 93.4 40.3 2.3e-19 69.3 8.8 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPX73386.1 - 1.9e-16 59.7 45.9 9.9e-11 40.9 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WTF PF03303.8 EPX73388.1 - 6.1e-05 22.5 0.1 9.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 WTF protein UPF0104 PF03706.8 EPX73388.1 - 0.0029 16.9 1.6 0.64 9.2 0.1 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0104) FecCD PF01032.13 EPX73388.1 - 0.015 14.1 4.0 0.02 13.7 2.8 1.1 1 0 0 1 1 1 0 FecCD transport family DUF912 PF06024.7 EPX73388.1 - 0.041 13.9 0.5 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AKAP_110 PF05716.8 EPX73389.1 - 0.0057 14.7 0.2 0.011 13.7 0.0 1.4 2 0 0 2 2 2 1 A-kinase anchor protein 110 kDa (AKAP 110) DUF682 PF05081.7 EPX73389.1 - 0.11 12.0 0.1 0.53 9.8 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF682) Oxidored_FMN PF00724.15 EPX73390.1 - 2.1e-101 339.3 0.0 1.3e-98 330.1 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cyt-b5 PF00173.23 EPX73391.1 - 2.2e-21 75.4 0.1 3e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MRP-L28 PF09812.4 EPX73391.1 - 0.049 13.4 1.6 0.09 12.6 1.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 WTF PF03303.8 EPX73392.1 - 0.00014 21.3 0.6 0.00024 20.6 0.4 1.4 1 1 0 1 1 1 1 WTF protein Ca_hom_mod PF14798.1 EPX73392.1 - 0.14 11.0 2.0 0.2 10.6 1.4 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator DUF3671 PF12420.3 EPX73392.1 - 2.3 8.2 12.2 7.1e+02 0.2 8.4 2.2 1 1 0 1 1 1 0 Protein of unknown function Tic20 PF09685.5 EPX73393.1 - 0.29 11.1 9.5 0.49 10.3 6.6 1.4 1 0 0 1 1 1 0 Tic20-like protein DUF1129 PF06570.6 EPX73393.1 - 0.45 9.8 3.9 0.66 9.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) MAGE_N PF12440.3 EPX73393.1 - 0.69 10.2 3.9 1 9.6 2.7 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal ACR_tran PF00873.14 EPX73393.1 - 4.6 4.5 5.6 6.1 4.1 3.9 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF1625 PF07787.7 EPX73393.1 - 6.6 5.9 6.5 8.9 5.4 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) HSP20 PF00011.16 EPX73394.1 - 4.7e-21 74.5 0.7 5.5e-21 74.3 0.5 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PIH1 PF08190.7 EPX73394.1 - 0.007 15.8 0.0 0.0077 15.7 0.0 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 CS PF04969.11 EPX73394.1 - 0.044 14.3 0.3 0.099 13.2 0.2 1.7 1 1 0 1 1 1 0 CS domain DUF4097 PF13349.1 EPX73394.1 - 0.056 12.9 0.1 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) OmpA PF00691.15 EPX73394.1 - 0.089 13.2 0.1 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 OmpA family Frag1 PF10277.4 EPX73395.1 - 2.3e-13 50.1 14.2 2.9e-13 49.8 9.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Herpes_U30 PF04523.8 EPX73395.1 - 0.051 11.0 0.3 0.066 10.6 0.2 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 DUF2759 PF10958.3 EPX73395.1 - 0.13 11.8 6.2 0.94 9.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2759) adh_short PF00106.20 EPX73396.1 - 3.8e-33 114.7 0.2 4.8e-33 114.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPX73396.1 - 2.3e-27 96.3 0.0 2.9e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPX73396.1 - 4.5e-15 55.7 0.1 6.7e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPX73396.1 - 0.0044 16.4 0.3 0.012 15.1 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EPX73396.1 - 0.0045 16.6 1.9 0.0087 15.7 1.3 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPX73396.1 - 0.056 12.5 0.1 0.13 11.4 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EPX73396.1 - 0.093 12.7 0.3 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding DIOX_N PF14226.1 EPX73398.1 - 1.1e-23 83.9 0.0 3e-23 82.5 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPX73398.1 - 1e-10 41.7 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 EPX73399.1 - 1.5e-36 125.7 0.8 2.2e-36 125.3 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPX73399.1 - 3.5e-29 102.2 0.3 4.3e-29 101.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPX73399.1 - 4.2e-18 65.6 0.3 6.2e-18 65.0 0.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EPX73399.1 - 0.0025 17.4 0.6 0.0058 16.2 0.5 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EPX73399.1 - 0.0037 16.7 0.7 0.033 13.6 0.5 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EPX73399.1 - 0.038 13.1 0.2 0.068 12.3 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EPX73400.1 - 6.7e-29 100.2 0.0 1.1e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EPX73400.1 - 1.5e-26 92.8 0.4 2.8e-26 91.9 0.3 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 EPX73400.1 - 0.02 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 EPX73400.1 - 0.078 12.9 0.0 0.34 10.9 0.0 2.0 1 1 0 1 1 1 0 TrkA-N domain Methyltransf_31 PF13847.1 EPX73401.1 - 1.5e-24 86.3 0.0 2.2e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX73401.1 - 1.3e-23 83.3 0.0 3.2e-23 82.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPX73401.1 - 1.4e-16 60.2 0.0 1.9e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EPX73401.1 - 1e-14 54.7 0.0 1.9e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX73401.1 - 3.8e-14 52.7 0.0 5.8e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX73401.1 - 1.8e-13 51.0 0.0 3.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX73401.1 - 3.9e-13 49.6 0.0 7.5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPX73401.1 - 4.7e-09 36.0 0.0 6.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 EPX73401.1 - 6.5e-07 28.3 0.0 8e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 EPX73401.1 - 7.7e-07 28.3 0.0 1.8e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MetW PF07021.7 EPX73401.1 - 9.6e-07 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EPX73401.1 - 2.8e-06 26.8 0.0 1.2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_29 PF03141.11 EPX73401.1 - 5.7e-06 24.9 0.2 0.0044 15.4 0.0 1.8 1 1 1 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 EPX73401.1 - 7.3e-06 26.0 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EPX73401.1 - 1.6e-05 24.3 0.0 2.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.10 EPX73401.1 - 0.00028 20.6 0.0 0.0064 16.1 0.0 2.3 2 1 0 2 2 2 1 Hypothetical methyltransferase RrnaAD PF00398.15 EPX73401.1 - 0.00087 18.3 0.0 0.0018 17.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase V_cholerae_RfbT PF05575.6 EPX73401.1 - 0.0054 15.8 0.0 0.0081 15.2 0.0 1.2 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein Methyltransf_32 PF13679.1 EPX73401.1 - 0.0055 16.3 0.0 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 EPX73401.1 - 0.035 13.4 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.7 EPX73401.1 - 0.04 12.7 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase CMAS PF02353.15 EPX73401.1 - 0.051 12.6 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase adh_short PF00106.20 EPX73402.1 - 6.7e-33 113.9 0.0 8.8e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPX73402.1 - 8.7e-30 104.2 0.0 1.1e-29 103.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPX73402.1 - 1.8e-12 47.2 0.0 2.5e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPX73402.1 - 0.0078 16.2 0.3 0.015 15.2 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPX73402.1 - 0.01 15.3 0.3 0.017 14.5 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EPX73402.1 - 0.012 15.2 1.6 0.024 14.3 1.1 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPX73402.1 - 0.02 14.0 0.3 0.032 13.3 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EPX73402.1 - 0.052 13.3 0.5 0.17 11.7 0.4 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase YjeF_N PF03853.10 EPX73402.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus Oxidored_nitro PF00148.14 EPX73402.1 - 0.12 10.9 0.1 0.31 9.6 0.0 1.7 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Zn_clus PF00172.13 EPX73404.1 - 7.4e-09 35.3 10.0 1.8e-08 34.1 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 EPX73405.1 - 5.9e-60 202.9 44.8 7.5e-60 202.6 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPX73405.1 - 2e-19 69.2 38.9 2.4e-19 69.0 26.6 1.3 1 1 0 1 1 1 1 Amino acid permease Glyco_hydro_31 PF01055.21 EPX73406.1 - 1.7e-159 531.4 5.0 2.2e-159 530.9 3.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 GGDN PF05165.7 EPX73407.1 - 0.048 12.6 0.1 0.048 12.6 0.1 1.0 1 0 0 1 1 1 0 GGDN family K_channel_TID PF07941.6 EPX73407.1 - 0.4 10.9 4.7 0.6 10.3 3.2 1.2 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain AA_permease PF00324.16 EPX73408.1 - 9.3e-129 429.8 46.5 1.1e-128 429.6 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPX73408.1 - 2.9e-36 124.9 49.0 4e-36 124.4 34.0 1.0 1 0 0 1 1 1 1 Amino acid permease Con-6 PF10346.4 EPX73409.1 - 9.9e-22 76.0 7.7 4.8e-14 51.4 0.1 2.5 3 0 0 3 3 3 2 Conidiation protein 6 MsyB PF13984.1 EPX73409.1 - 0.061 13.3 0.9 8.8 6.3 0.0 2.5 3 0 0 3 3 3 0 MsyB protein UPF0150 PF03681.10 EPX73409.1 - 0.086 12.4 0.1 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0150) PGA2 PF07543.7 EPX73409.1 - 1.9 8.2 6.8 2.2 8.0 4.7 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Con-6 PF10346.4 EPX73410.1 - 3.1e-37 125.6 5.4 9e-19 66.5 0.5 2.1 2 0 0 2 2 2 2 Conidiation protein 6 Aldedh PF00171.17 EPX73411.1 - 3.7e-174 579.3 0.1 4.6e-174 579.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPX73411.1 - 4.9e-07 28.8 0.0 7.9e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Oxidored_FMN PF00724.15 EPX73412.1 - 4.7e-101 338.2 0.0 6e-78 262.2 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family GalP_UDP_transf PF01087.17 EPX73413.1 - 2.4e-61 207.0 1.0 3.4e-61 206.5 0.4 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EPX73413.1 - 5.8e-48 162.5 0.5 1.7e-47 161.0 0.4 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.3 EPX73413.1 - 0.0016 18.6 0.9 0.0033 17.6 0.1 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EPX73413.1 - 0.0019 18.7 0.1 0.011 16.1 0.0 2.1 2 0 0 2 2 2 1 HIT domain GalP_UDP_transf PF01087.17 EPX73414.1 - 8.3e-46 156.3 0.2 9.5e-46 156.1 0.1 1.0 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain Epimerase PF01370.16 EPX73415.1 - 3.2e-49 167.4 0.0 3.8e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPX73415.1 - 2.6e-14 52.7 0.0 4.4e-14 51.9 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EPX73415.1 - 4.6e-08 32.2 0.0 1.3e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EPX73415.1 - 1.9e-07 30.2 0.0 4.9e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EPX73415.1 - 0.00015 20.6 0.0 0.0013 17.4 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EPX73415.1 - 0.00053 19.9 0.0 0.0036 17.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Aldose_epim PF01263.15 EPX73416.1 - 1.2e-67 228.1 1.0 1.6e-67 227.7 0.7 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.16 EPX73416.1 - 2.4e-44 151.5 0.0 3.3e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EPX73416.1 - 1.3e-24 85.9 0.1 2.4e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 EPX73416.1 - 5.7e-14 51.7 0.0 3.4e-12 45.8 0.0 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EPX73416.1 - 1e-13 50.6 0.0 2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EPX73416.1 - 2.3e-09 36.5 0.0 3.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EPX73416.1 - 5.5e-07 28.7 0.0 2.3e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EPX73416.1 - 7.8e-06 25.9 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EPX73416.1 - 5.4e-05 23.2 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EPX73416.1 - 0.00025 20.7 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 KR domain VirB8 PF04335.8 EPX73416.1 - 0.011 15.2 0.1 0.029 13.9 0.0 1.7 1 0 0 1 1 1 0 VirB8 protein NmrA PF05368.8 EPX73416.1 - 0.046 12.9 0.1 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EPX73416.1 - 0.25 10.6 0.6 0.49 9.7 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GalKase_gal_bdg PF10509.4 EPX73417.1 - 1.9e-20 71.8 0.0 4.3e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EPX73417.1 - 1.2e-16 60.5 0.3 1.2e-16 60.5 0.2 2.3 2 1 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPX73417.1 - 7.6e-12 45.2 0.0 1.5e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal Zn_clus PF00172.13 EPX73418.1 - 5.3e-07 29.4 11.0 1.1e-06 28.4 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPX73419.1 - 1.4e-32 112.7 37.0 2e-32 112.2 25.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FixP_N PF14715.1 EPX73419.1 - 0.11 11.9 12.2 0.44 9.9 0.9 3.3 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF4179 PF13786.1 EPX73419.1 - 0.32 11.2 1.2 1.2 9.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) MFS_1 PF07690.11 EPX73420.1 - 1.1e-32 113.1 32.9 1.1e-32 113.1 22.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPX73420.1 - 2.4e-05 22.7 3.5 4.2e-05 21.9 2.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3430 PF11912.3 EPX73421.1 - 3.5e-05 23.7 0.7 3.8e-05 23.6 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.3 EPX73421.1 - 0.0031 17.5 0.4 0.0052 16.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) WWbp PF10349.4 EPX73422.1 - 1.1e-09 39.1 0.1 3.7e-09 37.4 0.1 1.8 1 1 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EPX73422.1 - 0.00024 20.8 0.0 0.0004 20.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EPX73422.1 - 0.045 13.2 0.0 0.083 12.4 0.0 1.5 1 1 0 1 1 1 0 GRAM domain F-box PF00646.28 EPX73423.1 - 0.018 14.6 0.2 0.059 13.0 0.2 1.9 1 0 0 1 1 1 0 F-box domain FYVE PF01363.16 EPX73423.1 - 0.22 11.4 5.9 0.63 9.9 4.1 1.8 1 0 0 1 1 1 0 FYVE zinc finger Pkinase PF00069.20 EPX73424.1 - 8.6e-56 188.9 0.0 1.3e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73424.1 - 1.8e-25 89.5 0.1 6.6e-24 84.3 0.1 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX73424.1 - 7.8e-05 21.7 0.0 0.00019 20.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EPX73424.1 - 0.0005 19.4 0.1 0.00099 18.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EPX73424.1 - 0.0033 16.5 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GARS_N PF02844.10 EPX73424.1 - 0.03 14.7 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain APH PF01636.18 EPX73424.1 - 0.068 12.8 0.0 0.61 9.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family ParBc PF02195.13 EPX73425.1 - 1.5e-11 44.2 0.0 1.7e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain DUF1776 PF08643.5 EPX73426.1 - 3.5e-52 177.4 0.2 3.6e-48 164.2 0.1 2.1 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) DUF3105 PF11303.3 EPX73426.1 - 0.14 12.0 0.4 28 4.5 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3105) RskA PF10099.4 EPX73426.1 - 0.14 11.9 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA A_deaminase PF00962.17 EPX73427.1 - 1.7e-116 388.7 0.0 2.4e-116 388.2 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase ATP-synt_E PF05680.7 EPX73428.1 - 1.8e-18 66.2 0.3 2.1e-18 66.0 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain Amidase PF01425.16 EPX73429.1 - 5.9e-100 335.1 0.0 7.3e-100 334.8 0.0 1.0 1 0 0 1 1 1 1 Amidase GatB_N PF02934.10 EPX73430.1 - 3.1e-68 229.7 0.0 4e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain Cpn60_TCP1 PF00118.19 EPX73431.1 - 4.7e-140 467.4 13.4 5.4e-140 467.2 9.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1279 PF06916.8 EPX73432.1 - 2.9e-28 98.0 0.0 3.6e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Apc1 PF12859.2 EPX73433.1 - 4.1e-13 49.4 0.2 3.1e-12 46.6 0.0 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EPX73433.1 - 1.6e-05 24.8 10.2 0.028 14.6 0.3 5.1 5 0 0 5 5 5 2 Proteasome/cyclosome repeat Methyltransf_31 PF13847.1 EPX73433.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EPX73434.1 - 1e-65 221.4 0.0 4e-65 219.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73434.1 - 1.7e-33 115.8 0.0 2.6e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX73434.1 - 4.1e-05 22.6 0.0 9.4e-05 21.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPX73434.1 - 0.0063 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPX73434.1 - 0.0083 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 PAF-AH_p_II PF03403.8 EPX73435.1 - 6.1e-99 330.8 0.0 7.6e-99 330.5 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EPX73435.1 - 1.1e-07 31.6 0.0 2.2e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EPX73435.1 - 1.8e-05 23.7 0.0 0.0005 19.0 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EPX73435.1 - 0.00036 19.4 0.1 0.0023 16.8 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase Lipase_3 PF01764.20 EPX73435.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 EPX73435.1 - 0.015 15.1 0.0 0.037 13.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family RRM_1 PF00076.17 EPX73436.1 - 7.6e-08 31.8 0.0 1.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX73436.1 - 0.00018 21.4 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EPX73436.1 - 0.0035 17.7 0.2 0.0035 17.7 0.2 3.1 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 CLTH PF10607.4 EPX73437.1 - 3.6e-30 104.5 1.2 3.6e-30 104.5 0.9 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EPX73437.1 - 4.7e-07 29.3 1.0 1e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 LisH DUF3645 PF12359.3 EPX73437.1 - 0.089 11.9 0.6 6.4 6.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) OrfB_IS605 PF01385.14 EPX73437.1 - 0.091 12.1 3.2 0.17 11.2 0.4 2.4 2 1 0 2 2 2 0 Probable transposase DUF155 PF02582.9 EPX73437.1 - 0.34 10.8 4.2 0.17 11.8 1.3 1.6 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 SDA1 PF05285.7 EPX73438.1 - 3.3e-82 276.3 36.9 3.8e-82 276.1 21.9 2.3 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EPX73438.1 - 1.1e-17 63.9 0.3 3.5e-17 62.4 0.2 1.9 1 0 0 1 1 1 1 NUC130/3NT domain DEC-1_C PF04626.8 EPX73438.1 - 0.064 13.4 0.2 0.18 11.9 0.2 1.7 1 0 0 1 1 1 0 Dec-1 protein, C terminal region NUDIX PF00293.23 EPX73439.1 - 2.7e-27 95.0 0.0 3.8e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain RRM_6 PF14259.1 EPX73440.1 - 6e-23 80.6 0.2 8e-10 38.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX73440.1 - 5.7e-21 73.9 0.5 3.1e-12 45.9 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX73440.1 - 6.5e-19 67.5 0.3 4.3e-07 29.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPX73440.1 - 0.0016 18.1 0.2 2.1 8.1 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Proteasome PF00227.21 EPX73441.1 - 2.5e-56 189.9 0.0 3.2e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPX73441.1 - 4.8e-12 44.9 0.0 9.4e-12 44.0 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Abhydrolase_1 PF00561.15 EPX73442.1 - 7.7e-22 77.9 0.0 1.1e-20 74.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPX73442.1 - 2.2e-07 30.9 0.0 1.5e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L23eN PF03939.8 EPX73443.1 - 2.7e-20 72.1 11.5 5.2e-20 71.2 8.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EPX73443.1 - 1.9e-18 66.1 1.0 4.1e-18 65.1 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 Exo70 PF03081.10 EPX73445.1 - 2.9e-45 154.6 9.4 2.9e-45 154.6 6.5 2.3 2 1 1 3 3 3 2 Exo70 exocyst complex subunit Tricorn_C1 PF14684.1 EPX73445.1 - 0.42 10.5 3.0 4 7.3 0.1 2.8 2 0 0 2 2 2 0 Tricorn protease C1 domain DUF730 PF05325.6 EPX73445.1 - 0.87 9.4 3.8 6.3 6.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF730) Cyclin_N PF00134.18 EPX73446.1 - 5.4e-46 155.2 0.3 3.6e-45 152.6 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPX73446.1 - 4.2e-33 113.7 0.1 9.5e-33 112.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain PaREP1 PF05942.6 EPX73447.1 - 0.11 12.4 1.1 0.25 11.2 0.8 1.6 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family BRCT PF00533.21 EPX73448.1 - 9e-39 131.5 10.5 2.6e-08 33.9 0.0 6.7 6 1 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EPX73448.1 - 4.7e-26 90.4 0.5 3.9e-14 52.2 0.1 5.4 6 0 0 6 6 6 4 twin BRCT domain DUF640 PF04852.7 EPX73449.1 - 0.58 10.3 4.8 0.24 11.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF640) Syntaxin PF00804.20 EPX73449.1 - 3.5 7.8 21.6 0.051 13.7 0.7 3.3 2 1 1 3 3 3 0 Syntaxin RPN7 PF10602.4 EPX73450.1 - 3.4e-47 160.1 1.8 3.5e-47 160.0 0.4 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EPX73450.1 - 1.2e-16 60.9 1.1 5.6e-16 58.7 0.0 2.7 3 2 1 4 4 4 1 PCI domain DUF310 PF03750.8 EPX73450.1 - 0.041 14.0 0.1 0.14 12.3 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF310) PCI_Csn8 PF10075.4 EPX73450.1 - 0.073 12.8 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 HTH_DeoR PF08220.7 EPX73450.1 - 0.088 12.3 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Blo-t-5 PF11642.3 EPX73450.1 - 0.15 11.8 2.2 2.7 7.7 0.0 3.2 2 1 1 3 3 3 0 Mite allergen Blo t 5 Aminotran_1_2 PF00155.16 EPX73451.1 - 1.8e-35 122.5 0.0 3.3e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPX73451.1 - 0.12 11.5 0.0 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 Beta-eliminating lyase PEX11 PF05648.9 EPX73452.1 - 9.2e-51 172.2 3.3 1e-50 172.0 2.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SNF2_N PF00176.18 EPX73453.1 - 5e-82 275.0 1.8 7.2e-82 274.5 1.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPX73453.1 - 9.8e-14 50.9 0.0 3.2e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX73453.1 - 3.5e-07 30.2 0.2 2.1e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 EPX73453.1 - 0.019 14.3 1.3 0.06 12.7 0.0 2.2 2 0 0 2 2 2 0 DEAD_2 AAA_34 PF13872.1 EPX73453.1 - 0.1 11.3 0.0 0.23 10.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Nup84_Nup100 PF04121.8 EPX73454.1 - 2.4e-167 557.7 2.5 3.1e-167 557.3 1.7 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Aminotran_4 PF01063.14 EPX73455.1 - 4.7e-25 88.4 0.0 7e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Apq12 PF12716.2 EPX73456.1 - 6.3e-13 48.2 13.0 9.7e-13 47.6 9.0 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis Oxidored_q4 PF00507.14 EPX73456.1 - 0.023 14.4 1.8 0.029 14.1 1.3 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF3671 PF12420.3 EPX73456.1 - 0.086 12.8 2.2 0.12 12.3 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function Tmemb_cc2 PF10267.4 EPX73456.1 - 0.11 11.0 0.6 0.13 10.7 0.4 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PrgI PF12666.2 EPX73456.1 - 0.12 12.5 2.2 0.32 11.1 1.5 1.7 1 1 0 1 1 1 0 PrgI family protein Arginosuc_synth PF00764.14 EPX73457.1 - 5.3e-147 489.8 0.0 6e-147 489.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EPX73457.1 - 0.0049 16.1 0.0 0.0075 15.5 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC RXT2_N PF08595.6 EPX73458.1 - 7.2e-20 71.2 5.4 8.8e-19 67.7 1.7 2.5 2 1 0 2 2 2 1 RXT2-like, N-terminal SET PF00856.23 EPX73459.1 - 1.5e-24 87.1 0.3 1.5e-24 87.1 0.2 2.8 2 2 0 2 2 2 1 SET domain Pre-SET PF05033.11 EPX73459.1 - 1.5e-22 79.7 3.4 1.5e-22 79.7 2.3 2.8 3 0 0 3 3 3 1 Pre-SET motif Chromo PF00385.19 EPX73459.1 - 2.8e-14 52.5 0.7 5.3e-14 51.6 0.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PH_6 PF15406.1 EPX73460.1 - 1.7e-22 79.6 1.0 9.4e-21 73.9 0.0 3.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EPX73460.1 - 7.3e-05 22.9 0.0 0.00051 20.1 0.0 2.5 1 1 0 1 1 1 1 PH domain WTF PF03303.8 EPX73461.1 - 0.00018 20.9 1.0 0.00018 20.9 0.7 1.8 1 1 1 2 2 2 1 WTF protein Synaptobrevin PF00957.16 EPX73461.1 - 0.29 10.7 0.0 0.29 10.7 0.0 2.6 3 0 0 3 3 3 0 Synaptobrevin DUF3671 PF12420.3 EPX73461.1 - 0.74 9.8 7.3 6.5 6.7 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF2627 PF11118.3 EPX73461.1 - 0.99 9.5 3.8 1.3 9.1 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) DUF2975 PF11188.3 EPX73461.1 - 1.6 8.4 9.4 3.4 7.4 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) HILPDA PF15220.1 EPX73462.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated GST_N PF02798.15 EPX73463.1 - 5.2e-14 52.1 0.0 1.2e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPX73463.1 - 1.3e-13 50.6 0.0 3.1e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPX73463.1 - 8e-12 45.2 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPX73463.1 - 2.1e-11 43.6 0.1 4.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPX73463.1 - 1.7e-06 27.7 0.0 6.3e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPX73463.1 - 0.0018 18.7 0.1 0.0068 16.8 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cation_ATPase_C PF00689.16 EPX73465.1 - 1.1 8.7 9.6 0.27 10.7 4.2 1.6 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Cys_Met_Meta_PP PF01053.15 EPX73468.1 - 1.3e-58 198.1 0.0 6.8e-58 195.7 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RRM_1 PF00076.17 EPX73469.1 - 2e-16 59.3 0.0 2.5e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX73469.1 - 2.1e-12 46.8 0.0 2.8e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX73469.1 - 3.6e-11 42.7 0.0 5.1e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mob1_phocein PF03637.12 EPX73470.1 - 2.1e-76 255.4 1.8 2.5e-76 255.2 1.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family Acyltransferase PF01553.16 EPX73471.1 - 2e-24 85.5 0.0 3.6e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase MMR_HSR1_C PF08438.5 EPX73472.1 - 3.5e-30 104.4 0.0 5.3e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EPX73472.1 - 2.4e-18 66.1 0.0 4.4e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPX73472.1 - 2.3e-09 36.7 0.0 2.2e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPX73472.1 - 0.0029 17.4 0.1 0.0086 15.9 0.0 1.8 2 0 0 2 2 2 1 Dynamin family ATP_bind_1 PF03029.12 EPX73472.1 - 0.0046 16.5 0.2 2.3 7.6 0.1 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EPX73472.1 - 0.0075 15.7 0.1 3.6 6.9 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EPX73472.1 - 0.0076 15.0 0.0 0.016 14.0 0.0 1.5 1 0 0 1 1 1 1 ArgK protein AAA_29 PF13555.1 EPX73472.1 - 0.042 13.3 0.3 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EPX73472.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPX73472.1 - 0.13 12.5 0.0 0.43 10.8 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 EPX73472.1 - 0.13 13.0 0.1 0.69 10.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.5 EPX73472.1 - 0.15 11.2 0.0 0.57 9.3 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Ras PF00071.17 EPX73473.1 - 2.1e-48 163.7 0.7 2.5e-48 163.5 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX73473.1 - 2.1e-16 60.4 0.3 2.9e-16 60.0 0.2 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX73473.1 - 2.7e-08 33.2 0.0 2.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPX73473.1 - 6e-07 29.0 0.2 6.1e-06 25.7 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPX73473.1 - 4.3e-06 26.6 0.0 6.4e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPX73473.1 - 1.3e-05 24.5 0.1 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EPX73473.1 - 0.0025 17.5 0.6 0.0062 16.2 0.4 1.8 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EPX73473.1 - 0.019 14.8 0.1 0.024 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF3533 PF12051.3 EPX73473.1 - 0.14 10.9 0.6 0.15 10.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) WAPL PF07814.8 EPX73474.1 - 7.8e-27 93.9 9.2 1.2e-23 83.4 3.1 2.3 1 1 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin XPA_C PF05181.7 EPX73475.1 - 5.3e-29 99.5 0.9 1.5e-28 98.1 0.6 1.8 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EPX73475.1 - 4.7e-10 38.9 4.3 8.4e-10 38.1 3.0 1.4 1 0 0 1 1 1 1 XPA protein N-terminal zf-AD PF07776.10 EPX73475.1 - 0.076 13.0 2.2 0.2 11.6 1.5 1.8 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) Vma12 PF11712.3 EPX73475.1 - 2.2 7.9 10.9 0.072 12.7 2.8 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SOG2 PF10428.4 EPX73476.1 - 2.3e-56 191.3 14.8 5.9e-36 124.0 0.7 3.3 2 1 1 3 3 3 2 RAM signalling pathway protein LRR_8 PF13855.1 EPX73476.1 - 1.6e-15 56.5 7.7 3.4e-10 39.5 1.1 3.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EPX73476.1 - 1.1e-14 53.6 5.8 3.9e-07 29.5 0.1 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPX73476.1 - 7.1e-08 31.4 12.3 0.047 13.7 0.0 6.9 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EPX73476.1 - 9.3e-05 22.0 3.4 11 6.6 0.0 5.9 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.1 EPX73476.1 - 0.02 14.8 3.3 13 6.2 0.0 4.8 4 0 0 4 4 4 0 Leucine Rich repeat LRR_9 PF14580.1 EPX73476.1 - 0.11 12.0 0.5 0.29 10.6 0.1 1.8 2 0 0 2 2 2 0 Leucine-rich repeat PA_decarbox PF05870.6 EPX73476.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) Ribosomal_L14 PF00238.14 EPX73478.1 - 3.9e-43 146.1 1.4 4.3e-43 145.9 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DDE_1 PF03184.14 EPX73479.1 - 1.7e-60 203.8 0.8 2.9e-60 203.0 0.6 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EPX73479.1 - 1.8e-12 46.8 0.1 5.4e-12 45.3 0.1 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PX PF00787.19 EPX73480.1 - 8.1e-26 90.0 0.2 9.8e-26 89.7 0.1 1.1 1 0 0 1 1 1 1 PX domain RRM_1 PF00076.17 EPX73481.1 - 6.8e-19 67.2 0.1 1.1e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX73481.1 - 3.4e-12 46.1 0.0 7.9e-12 44.9 0.0 1.7 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX73481.1 - 3.6e-05 23.5 0.0 5.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.17 EPX73481.1 - 1.4 7.8 5.8 1.6 7.6 4.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PFU PF09070.6 EPX73482.1 - 1.2e-41 141.3 1.6 2.3e-41 140.4 1.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EPX73482.1 - 2.2e-39 131.9 26.5 1.8e-09 37.1 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat PUL PF08324.6 EPX73482.1 - 8.2e-38 129.7 5.1 1.1e-37 129.2 3.5 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 EPX73482.1 - 7.6e-06 25.6 0.0 0.01 15.6 0.0 3.6 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region CBF PF03914.12 EPX73483.1 - 1.5e-29 102.5 0.8 1.5e-29 102.5 0.6 3.7 3 1 0 3 3 3 2 CBF/Mak21 family NOC3p PF07540.6 EPX73483.1 - 2.4e-28 98.2 0.4 2.4e-28 98.2 0.2 3.1 4 0 0 4 4 4 1 Nucleolar complex-associated protein Neur_chan_memb PF02932.11 EPX73483.1 - 0.99 9.2 17.7 0.38 10.5 1.0 2.6 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Voltage_CLC PF00654.15 EPX73484.1 - 3.1e-76 256.7 34.1 5.4e-75 252.6 20.8 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 EPX73484.1 - 0.0046 16.7 0.0 0.039 13.7 0.0 2.2 2 0 0 2 2 2 1 CBS domain Clat_adaptor_s PF01217.15 EPX73485.1 - 1e-54 184.0 2.1 1.1e-54 183.9 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PIG-H PF10181.4 EPX73486.1 - 1.6e-22 78.8 0.0 2.8e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Ribosomal_S2 PF00318.15 EPX73487.1 - 6e-42 143.2 0.1 4.1e-20 71.9 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_L27e PF01777.13 EPX73488.1 - 7.2e-38 128.5 2.3 9.3e-38 128.2 1.6 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EPX73488.1 - 0.023 14.4 0.1 0.054 13.2 0.1 1.8 1 0 0 1 1 1 0 KOW motif ORC2 PF04084.9 EPX73490.1 - 1.1e-90 303.8 3.1 1.4e-90 303.5 2.2 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 F_bP_aldolase PF01116.15 EPX73490.1 - 0.027 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II RhoGAP PF00620.22 EPX73490.1 - 0.062 12.9 0.1 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 RhoGAP domain HI0933_like PF03486.9 EPX73490.1 - 0.2 10.0 0.0 0.34 9.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Exo_endo_phos PF03372.18 EPX73491.1 - 3.5e-21 76.2 0.3 4.5e-21 75.9 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EPX73491.1 - 0.063 12.8 0.1 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase WD40 PF00400.27 EPX73492.1 - 3.6e-28 96.3 8.5 1.4e-05 24.7 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EPX73492.1 - 8.1e-05 22.4 0.1 0.038 13.6 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Kelch_6 PF13964.1 EPX73492.1 - 0.0002 21.3 0.4 0.082 13.1 0.0 4.1 5 0 0 5 5 5 1 Kelch motif Gemin7 PF11095.3 EPX73493.1 - 1.6e-12 47.0 0.0 2e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) GSHPx PF00255.14 EPX73494.1 - 6.9e-44 147.6 0.1 9e-44 147.2 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EPX73494.1 - 1.3e-06 28.1 0.0 2.2e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPX73494.1 - 6.4e-05 22.5 0.0 0.00016 21.2 0.0 1.7 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 EPX73494.1 - 0.062 13.4 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) Adaptin_N PF01602.15 EPX73495.1 - 1.8e-116 389.5 9.6 2.2e-116 389.2 6.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EPX73495.1 - 6.4e-17 61.9 0.0 1.3e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EPX73495.1 - 0.00037 20.7 1.2 1.4 9.2 0.0 4.4 3 1 1 4 4 4 3 HEAT repeats cwf18 PF08315.7 EPX73496.1 - 6e-31 107.5 8.4 6e-31 107.5 5.8 1.3 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor Ribosomal_S8e PF01201.17 EPX73497.1 - 6.5e-37 126.6 9.1 5.1e-36 123.7 6.3 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e Enkurin PF13864.1 EPX73497.1 - 0.0098 16.0 0.1 0.0098 16.0 0.1 2.5 2 1 0 2 2 2 1 Calmodulin-binding HPD PF05044.7 EPX73497.1 - 0.037 13.6 0.1 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 Homeo-prospero domain DUF3959 PF13105.1 EPX73497.1 - 7.7 5.7 7.6 1.5 8.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Ribosomal_60s PF00428.14 EPX73498.1 - 1.8e-24 85.9 10.7 2.3e-24 85.6 7.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ank_2 PF12796.2 EPX73499.1 - 2.2e-14 53.5 0.9 2.9e-12 46.7 0.7 2.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPX73499.1 - 4e-14 52.3 0.2 1.9e-12 46.9 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPX73499.1 - 5.6e-12 45.8 0.4 2.9e-08 34.0 0.1 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EPX73499.1 - 1.4e-11 43.6 2.0 8.1e-07 28.5 0.1 4.1 3 1 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EPX73499.1 - 1.3e-09 37.3 0.4 1.5e-05 24.7 0.1 4.1 4 1 0 4 4 4 2 Ankyrin repeat CPL PF08144.6 EPX73500.1 - 2.3e-24 85.8 0.2 4.5e-23 81.7 0.0 3.0 3 0 0 3 3 3 1 CPL (NUC119) domain PUF PF00806.14 EPX73500.1 - 2.7e-05 23.4 0.3 23 4.7 0.0 5.5 5 0 0 5 5 5 0 Pumilio-family RNA binding repeat FAD-oxidase_C PF02913.14 EPX73500.1 - 0.036 13.3 0.2 0.036 13.3 0.1 2.8 3 1 0 3 3 3 0 FAD linked oxidases, C-terminal domain Nop14 PF04147.7 EPX73500.1 - 0.16 9.8 31.1 0.22 9.4 18.3 2.2 2 0 0 2 2 2 0 Nop14-like family Merozoite_SPAM PF07133.6 EPX73500.1 - 0.26 11.1 29.1 0.61 9.9 20.2 1.6 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Daxx PF03344.10 EPX73500.1 - 0.28 9.6 25.2 0.39 9.1 17.4 1.2 1 0 0 1 1 1 0 Daxx Family ADP_ribosyl_GH PF03747.9 EPX73500.1 - 0.41 10.3 0.0 0.41 10.3 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase RRN3 PF05327.6 EPX73500.1 - 0.42 8.6 11.2 0.76 7.8 7.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Formyl_trans_N PF00551.14 EPX73501.1 - 2.9e-43 147.5 0.1 3.3e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Ham1p_like PF01725.11 EPX73503.1 - 2e-49 167.5 0.0 2.3e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family RNase_P_Rpp14 PF01900.14 EPX73504.1 - 1.3e-37 127.9 0.0 1.5e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Rpp14/Pop5 family TB2_DP1_HVA22 PF03134.14 EPX73505.1 - 1.6e-29 101.4 7.0 2.8e-29 100.6 4.8 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF3970 PF13113.1 EPX73505.1 - 0.11 12.2 0.1 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) CTDII PF01556.13 EPX73506.1 - 3.4e-25 87.7 0.3 3.9e-21 74.7 0.0 2.8 2 1 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EPX73506.1 - 4.8e-25 87.0 2.6 7.6e-25 86.4 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain Gly_rich PF12810.2 EPX73506.1 - 0.09 12.3 16.5 0.15 11.5 11.4 1.3 1 0 0 1 1 1 0 Glycine rich protein EF-hand_1 PF00036.27 EPX73507.1 - 6.3e-26 87.6 9.4 2.1e-07 29.7 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EPX73507.1 - 8.5e-23 80.2 2.3 1.3e-12 47.6 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPX73507.1 - 3.2e-21 73.6 8.9 1.1e-06 27.7 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EPX73507.1 - 4.1e-21 72.9 5.2 4.3e-05 23.0 0.2 4.3 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EPX73507.1 - 1.1e-14 53.7 13.0 8.6e-05 22.0 0.7 4.5 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EPX73507.1 - 1.1e-07 31.8 0.1 0.0062 16.5 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EPX73507.1 - 6.1e-05 22.7 6.3 0.29 10.8 0.3 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EPX73507.1 - 0.002 18.0 0.0 0.16 11.8 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain DNA_Packaging PF11053.3 EPX73507.1 - 0.041 13.4 0.2 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Terminase DNA packaging enzyme EPL1 PF10513.4 EPX73508.1 - 4.4e-29 101.7 3.1 9.5e-29 100.7 2.1 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like Clp1 PF06807.9 EPX73509.1 - 2.6e-09 37.1 0.0 4.5e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EPX73509.1 - 6.5e-06 25.9 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EPX73509.1 - 0.0044 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EPX73509.1 - 0.0051 16.2 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EPX73509.1 - 0.015 16.1 0.0 0.031 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPX73509.1 - 0.017 15.2 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EPX73509.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ArgK PF03308.11 EPX73509.1 - 0.037 12.7 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Gtr1_RagA PF04670.7 EPX73509.1 - 0.054 12.6 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EPX73509.1 - 0.061 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EPX73509.1 - 0.064 13.5 0.0 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.12 EPX73509.1 - 0.071 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EPX73509.1 - 0.087 12.5 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase G-alpha PF00503.15 EPX73509.1 - 0.16 10.6 3.0 15 4.1 2.2 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Ribosomal_L30 PF00327.15 EPX73510.1 - 4.1e-11 42.3 0.0 5.4e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e eIF-6 PF01912.13 EPX73512.1 - 5.7e-85 283.4 0.9 7e-85 283.1 0.6 1.1 1 0 0 1 1 1 1 eIF-6 family Myosin_head PF00063.16 EPX73513.1 - 8.2e-238 790.9 10.6 1.6e-237 789.9 7.4 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EPX73513.1 - 7.4e-20 70.7 2.2 4.7e-19 68.2 1.6 2.5 1 0 0 1 1 1 1 DIL domain AAA_22 PF13401.1 EPX73513.1 - 2.7e-05 24.3 0.7 0.00053 20.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain IQ PF00612.22 EPX73513.1 - 0.00016 20.9 14.8 0.1 12.3 0.1 4.7 4 0 0 4 4 4 3 IQ calmodulin-binding motif BAR PF03114.13 EPX73514.1 - 3.2e-30 105.3 3.4 5.4e-30 104.6 2.4 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EPX73514.1 - 2.8e-10 39.4 0.0 5.5e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPX73514.1 - 2.5e-09 36.5 0.0 6.7e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EPX73514.1 - 4.6e-05 22.8 0.0 9.9e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Prefoldin_3 PF13758.1 EPX73514.1 - 0.005 16.5 2.4 0.005 16.5 1.7 1.9 2 0 0 2 2 2 1 Prefoldin subunit Peptidase_M28 PF04389.12 EPX73515.1 - 6.2e-36 123.7 0.1 1.2e-35 122.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EPX73515.1 - 5.2e-05 22.8 0.0 5.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 NPCC PF08058.6 EPX73515.1 - 0.018 14.8 1.3 0.055 13.3 0.1 2.5 2 1 0 2 2 2 0 Nuclear pore complex component Peptidase_M42 PF05343.9 EPX73515.1 - 0.065 11.9 0.0 0.32 9.7 0.0 1.8 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase DUF2431 PF10354.4 EPX73516.1 - 9.6e-55 185.0 0.1 1.3e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) MTS PF05175.9 EPX73516.1 - 0.00072 18.9 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EPX73516.1 - 0.026 14.5 0.0 0.043 13.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain SpecificRecomb PF10136.4 EPX73516.1 - 0.15 10.0 0.0 0.21 9.5 0.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase Myb_DNA-binding PF00249.26 EPX73517.1 - 1.5e-06 28.1 0.0 4.3e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Vps39_2 PF10367.4 EPX73517.1 - 0.23 11.6 1.8 2.5 8.3 0.0 2.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF1974 PF09317.6 EPX73517.1 - 0.74 9.1 0.0 0.74 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1974) BRE1 PF08647.6 EPX73518.1 - 3.1e-14 52.6 7.2 3.1e-14 52.6 5.0 5.7 4 2 2 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EPX73518.1 - 2.4e-06 27.4 9.5 4.8e-06 26.4 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX73518.1 - 6.6e-06 25.6 9.4 1.5e-05 24.5 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX73518.1 - 7.6e-06 25.4 7.2 1.6e-05 24.5 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX73518.1 - 3.1e-05 23.6 7.9 6.7e-05 22.5 5.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPX73518.1 - 0.00011 21.9 7.6 0.00024 20.8 5.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EPX73518.1 - 0.0014 18.4 4.0 0.0014 18.4 2.7 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EPX73518.1 - 0.0019 18.2 4.6 0.0019 18.2 3.2 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger zf-UDP PF14569.1 EPX73518.1 - 0.016 14.8 0.6 0.048 13.4 0.4 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_6 PF14835.1 EPX73518.1 - 0.03 14.1 2.5 0.061 13.1 1.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EPX73518.1 - 0.098 12.3 5.5 0.13 11.9 2.6 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EPX73518.1 - 0.34 10.5 7.8 0.77 9.3 5.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EPX73518.1 - 0.45 10.0 4.9 1.2 8.7 3.4 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF778 PF05608.7 EPX73518.1 - 1.3 8.9 3.5 60 3.5 2.5 3.2 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Pep3_Vps18 PF05131.9 EPX73519.1 - 6.5e-32 109.9 3.5 1.5e-30 105.5 0.3 2.9 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.4 EPX73519.1 - 6.5e-08 32.7 1.1 2.5e-07 30.8 0.8 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 TPR_12 PF13424.1 EPX73519.1 - 9.5e-05 22.2 0.7 0.34 10.8 0.0 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 EPX73519.1 - 0.0014 18.5 8.1 0.0036 17.2 5.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_7 PF13176.1 EPX73519.1 - 0.018 14.8 0.0 2.4 8.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-Apc11 PF12861.2 EPX73519.1 - 0.036 13.9 1.7 0.14 11.9 0.8 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_2 PF07719.12 EPX73519.1 - 0.042 13.7 3.6 2 8.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_5 PF14634.1 EPX73519.1 - 0.061 13.0 9.6 0.056 13.1 5.1 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EPX73519.1 - 0.082 12.5 8.3 0.24 11.0 5.8 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPX73519.1 - 0.15 11.8 11.8 0.12 12.2 6.2 2.3 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.2 EPX73519.1 - 0.19 11.8 3.8 0.54 10.3 2.6 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger Rhomboid PF01694.17 EPX73520.1 - 1.1e-18 67.6 11.4 1.7e-18 67.0 7.9 1.2 1 0 0 1 1 1 1 Rhomboid family Mog1 PF04603.7 EPX73521.1 - 7.2e-47 158.8 0.3 9.7e-47 158.4 0.2 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Glucan_synthase PF02364.10 EPX73522.1 - 0 1465.0 0.0 0 1464.2 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EPX73522.1 - 8.5e-34 115.9 0.3 2.1e-33 114.7 0.2 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 zf-LITAF-like PF10601.4 EPX73523.1 - 0.72 9.7 6.4 0.17 11.7 2.1 1.8 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain HEAT PF02985.17 EPX73524.1 - 2.9e-22 76.6 12.1 0.00066 19.5 0.0 11.6 12 0 0 12 12 12 5 HEAT repeat HEAT_2 PF13646.1 EPX73524.1 - 2.4e-20 72.5 14.1 1.3e-08 34.9 0.5 7.6 4 2 3 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 EPX73524.1 - 4.3e-18 65.2 29.4 5.3e-07 29.9 0.1 11.0 11 1 2 13 13 13 6 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPX73524.1 - 8.4e-11 42.1 1.9 0.0034 17.7 0.0 6.2 4 2 3 7 7 7 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EPX73524.1 - 1e-05 25.2 0.0 0.11 12.1 0.0 4.9 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis DUF4042 PF13251.1 EPX73524.1 - 0.00018 21.0 2.2 1.8 7.9 0.0 5.9 6 0 0 6 6 6 1 Domain of unknown function (DUF4042) Arm PF00514.18 EPX73524.1 - 0.00056 19.6 5.4 6.5 6.7 0.0 6.5 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.6 EPX73524.1 - 0.06 12.8 0.1 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 DNA alkylation repair enzyme ParcG PF10274.4 EPX73524.1 - 0.064 13.1 0.0 0.78 9.6 0.0 2.8 3 0 0 3 3 3 0 Parkin co-regulated protein Peptidase_C14 PF00656.17 EPX73525.1 - 3.6e-65 220.0 0.0 4.9e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain PGM_PMM_I PF02878.11 EPX73526.1 - 8.2e-42 141.9 0.1 1.4e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EPX73526.1 - 1.8e-20 73.2 0.0 4.1e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EPX73526.1 - 1.1e-12 47.9 0.1 2e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EPX73526.1 - 4e-07 29.9 0.0 1.4e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain OSCP PF00213.13 EPX73527.1 - 1.4e-44 152.0 0.5 1.6e-44 151.8 0.4 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Metallophos PF00149.23 EPX73528.1 - 1.8e-11 43.8 0.5 2e-10 40.4 0.4 2.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Thioredoxin_6 PF13848.1 EPX73529.1 - 0.00017 21.4 0.0 0.00056 19.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain NAD_binding_10 PF13460.1 EPX73530.1 - 1.1e-09 38.6 0.0 1.3e-08 35.0 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPX73530.1 - 2.2e-07 30.5 0.0 4.6e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPX73530.1 - 0.0012 17.7 0.0 0.098 11.5 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.20 EPX73530.1 - 0.0013 18.6 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EPX73530.1 - 0.0036 16.0 0.0 0.0097 14.6 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPX73530.1 - 0.14 11.0 0.0 2.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein AMPKBI PF04739.10 EPX73531.1 - 1.2e-27 95.6 1.6 3.3e-27 94.2 1.1 1.7 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain FNIP PF05725.7 EPX73531.1 - 0.13 12.2 0.6 0.27 11.2 0.4 1.5 1 0 0 1 1 1 0 FNIP Repeat PIG-X PF08320.7 EPX73532.1 - 3.3e-37 127.7 1.3 8.7e-37 126.4 0.9 1.7 1 1 0 1 1 1 1 PIG-X / PBN1 Pkinase PF00069.20 EPX73533.1 - 4.5e-60 202.9 0.0 7.8e-60 202.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73533.1 - 5.5e-28 97.7 0.0 2.1e-27 95.8 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX73533.1 - 2.5e-10 39.7 0.0 4.8e-10 38.8 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EPX73533.1 - 4.5e-05 23.3 0.0 8.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EPX73533.1 - 0.0013 17.8 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 EPX73533.1 - 0.0067 15.0 0.0 0.021 13.4 0.0 1.7 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukC Pox_ser-thr_kin PF05445.6 EPX73533.1 - 0.016 14.0 0.4 0.029 13.1 0.2 1.5 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1891 PF09004.5 EPX73533.1 - 0.033 13.5 0.3 0.088 12.2 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) YrbL-PhoP_reg PF10707.4 EPX73533.1 - 0.033 13.5 0.4 1.2 8.3 0.0 2.4 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EPX73533.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EPX73533.1 - 0.094 12.0 0.6 0.34 10.2 0.4 2.0 1 1 0 1 1 1 0 RIO1 family AAA_18 PF13238.1 EPX73534.1 - 7.6e-24 84.4 0.3 1.3e-23 83.6 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EPX73534.1 - 1.7e-12 48.2 0.1 2.4e-12 47.7 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPX73534.1 - 3.3e-07 30.2 0.0 4.7e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EPX73534.1 - 1.1e-05 25.6 0.7 7.2e-05 23.0 0.5 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EPX73534.1 - 1.8e-05 24.7 0.0 4.1e-05 23.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain KTI12 PF08433.5 EPX73534.1 - 0.00015 21.1 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 EPX73534.1 - 0.00035 20.7 0.0 0.00082 19.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPX73534.1 - 0.00054 19.7 0.1 0.0011 18.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ADK PF00406.17 EPX73534.1 - 0.00078 19.3 0.3 0.0052 16.6 0.0 2.0 2 0 0 2 2 2 1 Adenylate kinase NTPase_1 PF03266.10 EPX73534.1 - 0.0015 18.2 0.0 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 NTPase MobB PF03205.9 EPX73534.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EPX73534.1 - 0.0017 17.5 0.1 0.05 12.7 0.0 2.1 2 0 0 2 2 2 1 KaiC RNA_helicase PF00910.17 EPX73534.1 - 0.0022 18.1 0.0 0.0097 16.0 0.0 2.0 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 EPX73534.1 - 0.0022 17.4 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EPX73534.1 - 0.0025 17.8 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.12 EPX73534.1 - 0.0043 16.4 0.1 0.86 8.9 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_14 PF13173.1 EPX73534.1 - 0.006 16.4 0.0 0.014 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EPX73534.1 - 0.0063 15.9 0.0 0.029 13.8 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EPX73534.1 - 0.0085 15.2 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EPX73534.1 - 0.011 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.7 EPX73534.1 - 0.011 14.8 0.1 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EPX73534.1 - 0.011 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SKI PF01202.17 EPX73534.1 - 0.014 15.2 0.5 0.1 12.4 0.3 2.0 1 1 0 1 1 1 0 Shikimate kinase AAA_25 PF13481.1 EPX73534.1 - 0.024 14.0 0.0 0.058 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EPX73534.1 - 0.029 13.8 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 EPX73534.1 - 0.031 12.8 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 EPX73534.1 - 0.032 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Parvo_NS1 PF01057.12 EPX73534.1 - 0.037 12.8 0.0 0.075 11.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Miro PF08477.8 EPX73534.1 - 0.039 14.4 0.0 0.11 12.9 0.0 1.8 2 1 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 EPX73534.1 - 0.043 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain malic PF00390.14 EPX73534.1 - 0.061 12.9 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain MMR_HSR1 PF01926.18 EPX73534.1 - 0.062 13.2 0.0 0.099 12.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.17 EPX73534.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MCM PF00493.18 EPX73534.1 - 0.071 11.8 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family PduV-EutP PF10662.4 EPX73534.1 - 0.077 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 EPX73534.1 - 0.086 12.2 0.0 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain Peptidase_M41 PF01434.13 EPX73535.1 - 4.4e-71 238.7 0.7 7.3e-71 238.0 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EPX73535.1 - 1.2e-41 142.0 0.0 2.2e-41 141.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPX73535.1 - 5.4e-06 26.5 1.0 0.00011 22.3 0.4 2.8 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EPX73535.1 - 6.9e-06 26.2 0.3 0.0013 18.8 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EPX73535.1 - 8.3e-06 25.5 0.1 4.4e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EPX73535.1 - 1.7e-05 23.7 0.0 3.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EPX73535.1 - 3.2e-05 24.7 0.0 8.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPX73535.1 - 0.00015 21.4 0.0 0.00048 19.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EPX73535.1 - 0.00049 19.2 0.0 0.00086 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EPX73535.1 - 0.0015 17.9 0.1 0.005 16.2 0.0 1.9 2 0 0 2 2 1 1 IstB-like ATP binding protein NACHT PF05729.7 EPX73535.1 - 0.0017 18.0 0.7 0.094 12.3 0.0 2.6 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.1 EPX73535.1 - 0.0029 17.5 0.0 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPX73535.1 - 0.0051 16.2 2.5 0.026 13.9 0.1 2.5 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EPX73535.1 - 0.0077 15.3 0.5 0.031 13.3 0.1 2.0 1 1 1 2 2 2 1 Zeta toxin AAA_28 PF13521.1 EPX73535.1 - 0.0078 16.1 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EPX73535.1 - 0.0098 15.0 0.2 0.0098 15.0 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EPX73535.1 - 0.01 15.7 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EPX73535.1 - 0.019 15.2 0.0 0.051 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPX73535.1 - 0.023 14.6 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EPX73535.1 - 0.027 13.4 0.0 0.098 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Peptidase_M50B PF13398.1 EPX73535.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase M50B-like Sigma54_activat PF00158.21 EPX73535.1 - 0.08 12.4 0.0 0.35 10.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EPX73535.1 - 0.11 12.5 0.1 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 EPX73535.1 - 0.13 11.3 0.1 0.47 9.5 0.0 1.9 2 0 0 2 2 2 0 KaiC ATP-synt_D PF01813.12 EPX73536.1 - 2.8e-63 213.0 4.0 4.9e-63 212.2 2.8 1.4 1 0 0 1 1 1 1 ATP synthase subunit D GAS PF13851.1 EPX73536.1 - 0.027 13.6 5.4 0.17 11.0 0.1 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Viral_P18 PF04521.8 EPX73536.1 - 5.5 6.4 5.8 4.6 6.7 0.2 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Cwf_Cwc_15 PF04889.7 EPX73536.1 - 5.9 6.5 15.2 2 8.0 6.8 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein EXOSC1 PF10447.4 EPX73537.1 - 4.9e-25 87.2 2.5 7.5e-25 86.6 1.7 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 EPX73537.1 - 0.013 15.5 1.9 0.12 12.4 1.3 2.2 1 1 0 1 1 1 0 S1 RNA binding domain ECR1_N PF14382.1 EPX73537.1 - 0.082 12.2 0.1 0.23 10.7 0.1 1.8 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region DUF705 PF05152.7 EPX73537.1 - 0.091 11.7 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) LSM PF01423.17 EPX73538.1 - 9.2e-15 53.9 0.2 1.2e-14 53.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 EPX73538.1 - 0.063 12.8 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Lyase_1 PF00206.15 EPX73539.1 - 6e-42 143.9 0.0 9.9e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EPX73539.1 - 7.7e-20 70.6 0.1 1.8e-19 69.5 0.1 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1989 PF09347.5 EPX73540.1 - 6.1e-51 172.1 0.0 7.8e-51 171.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) CytochromB561_N PF09786.4 EPX73541.1 - 0.0043 15.5 0.4 0.0056 15.1 0.3 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal TPR_11 PF13414.1 EPX73542.1 - 3.8e-55 183.4 22.1 1.8e-09 37.1 0.0 11.2 7 2 3 11 11 11 10 TPR repeat TPR_1 PF00515.23 EPX73542.1 - 2.5e-41 137.6 23.9 6.8e-05 22.2 0.0 16.4 16 0 0 16 16 16 10 Tetratricopeptide repeat TPR_2 PF07719.12 EPX73542.1 - 5e-40 132.1 23.5 5.6e-06 25.8 0.0 16.7 17 0 0 17 17 17 7 Tetratricopeptide repeat TPR_19 PF14559.1 EPX73542.1 - 5.7e-32 109.8 20.3 1.6e-06 28.3 0.1 12.4 10 3 2 13 13 12 7 Tetratricopeptide repeat TPR_14 PF13428.1 EPX73542.1 - 8.4e-32 106.7 9.1 0.00065 20.1 0.0 16.2 11 5 7 18 18 17 5 Tetratricopeptide repeat TPR_16 PF13432.1 EPX73542.1 - 4.5e-31 106.8 5.4 9.3e-07 29.3 0.0 12.6 9 5 4 13 13 12 5 Tetratricopeptide repeat TPR_17 PF13431.1 EPX73542.1 - 7.8e-30 100.5 11.3 0.018 15.2 0.0 13.8 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_12 PF13424.1 EPX73542.1 - 3.5e-28 97.3 26.9 0.00055 19.8 0.0 13.3 11 3 3 14 14 14 7 Tetratricopeptide repeat TPR_8 PF13181.1 EPX73542.1 - 1.2e-27 93.5 13.6 0.0023 17.5 0.2 13.8 13 2 1 14 14 13 6 Tetratricopeptide repeat TPR_9 PF13371.1 EPX73542.1 - 8e-14 51.2 3.4 7.2e-05 22.5 0.0 8.9 8 2 2 10 10 10 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPX73542.1 - 9.4e-14 50.0 10.3 0.6 10.0 0.0 12.8 13 1 1 14 14 14 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPX73542.1 - 2.9e-12 46.1 12.8 3.8 8.1 0.0 12.5 13 1 1 14 14 12 1 Tetratricopeptide repeat Apc3 PF12895.2 EPX73542.1 - 3.2e-11 43.2 35.6 0.0035 17.4 0.0 10.4 9 3 3 12 12 10 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EPX73542.1 - 0.00036 20.5 4.8 1 9.5 0.0 6.3 8 2 2 10 10 8 1 Tetratricopeptide repeat TPR_4 PF07721.9 EPX73542.1 - 0.0029 17.8 0.0 73 4.2 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPX73542.1 - 0.0098 15.8 7.2 54 3.9 0.0 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Ribosomal_L36e PF01158.13 EPX73542.1 - 0.019 14.9 0.4 0.097 12.6 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L36e PPTA PF01239.17 EPX73542.1 - 0.67 9.4 10.1 7.2 6.1 0.0 5.4 6 0 0 6 6 6 0 Protein prenyltransferase alpha subunit repeat Sec1 PF00995.18 EPX73543.1 - 1.3e-146 489.5 1.3 1.6e-146 489.2 0.9 1.0 1 0 0 1 1 1 1 Sec1 family SBP_bac_3 PF00497.15 EPX73544.1 - 0.011 14.9 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Sif PF06767.6 EPX73544.1 - 0.047 12.4 0.0 0.084 11.6 0.0 1.4 1 0 0 1 1 1 0 Sif protein Pkinase PF00069.20 EPX73545.1 - 4.6e-74 248.8 0.0 7.3e-74 248.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73545.1 - 3.4e-39 134.4 0.0 6e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EPX73545.1 - 6.7e-13 48.6 0.2 1.3e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EPX73545.1 - 1.2e-09 37.5 0.0 5.2e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EPX73545.1 - 6.2e-05 22.4 0.3 0.00021 20.7 0.1 1.8 2 0 0 2 2 2 1 RIO1 family YukC PF10140.4 EPX73545.1 - 0.0007 18.2 0.1 0.0011 17.6 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 EPX73545.1 - 0.088 11.8 0.3 0.18 10.8 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX73545.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Nic96 PF04097.9 EPX73546.1 - 3.5e-154 514.3 0.5 4.4e-154 513.9 0.4 1.1 1 0 0 1 1 1 1 Nup93/Nic96 UPF0560 PF10577.4 EPX73547.1 - 0.0084 14.4 0.4 0.011 14.0 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 HSP70 PF00012.15 EPX73548.1 - 8.9e-272 902.3 5.9 1e-271 902.2 4.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPX73548.1 - 5.4e-17 61.3 0.2 5.5e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EPX73548.1 - 5.2e-05 22.9 0.0 0.00015 21.4 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EPX73548.1 - 0.0016 17.6 1.3 0.016 14.3 0.1 2.7 2 1 0 3 3 3 1 Hydantoinase/oxoprolinase Ppx-GppA PF02541.11 EPX73548.1 - 0.019 14.1 0.4 0.043 13.0 0.0 1.7 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Metallophos PF00149.23 EPX73549.1 - 3.8e-43 147.2 0.1 4.7e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.2 EPX73550.1 - 1.4e-33 113.9 51.7 3.2e-10 39.4 0.1 9.5 5 2 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPX73550.1 - 3.3e-24 84.4 51.8 6.1e-10 38.7 0.3 7.4 4 2 5 9 9 9 9 Leucine rich repeat LRR_1 PF00560.28 EPX73550.1 - 5.8e-12 43.8 49.0 0.061 13.3 0.0 14.3 13 1 0 13 13 13 4 Leucine Rich Repeat LRR_7 PF13504.1 EPX73550.1 - 1.3e-08 33.6 46.1 0.37 11.1 0.0 13.7 14 0 0 14 14 14 5 Leucine rich repeat LRR_6 PF13516.1 EPX73550.1 - 9.8e-07 28.2 44.0 0.1 12.7 0.0 10.8 11 1 0 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.1 EPX73550.1 - 0.44 10.0 15.5 1.9 7.9 0.1 4.6 2 2 3 5 5 5 0 Leucine-rich repeat SUR7 PF06687.7 EPX73551.1 - 9e-20 71.1 16.1 1.2e-19 70.7 11.2 1.2 1 0 0 1 1 1 1 SUR7/PalI family GWT1 PF06423.7 EPX73551.1 - 0.14 12.2 6.4 0.027 14.5 1.9 1.8 2 0 0 2 2 2 0 GWT1 MARVEL PF01284.18 EPX73551.1 - 1.8 8.3 15.7 44 3.8 10.9 2.4 1 1 0 1 1 1 0 Membrane-associating domain COX6A PF02046.10 EPX73552.1 - 2.3e-36 124.2 0.9 2.3e-36 124.1 0.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa adh_short PF00106.20 EPX73553.1 - 2e-28 99.3 1.8 2.4e-28 99.1 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPX73553.1 - 1.5e-26 93.6 0.2 1.9e-26 93.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPX73553.1 - 1.6e-18 66.9 1.1 2.2e-18 66.5 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPX73553.1 - 0.00016 21.2 0.5 0.00025 20.5 0.4 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ACT PF01842.20 EPX73553.1 - 0.0053 16.2 0.0 0.029 13.8 0.0 2.2 2 1 0 2 2 2 1 ACT domain THF_DHG_CYH_C PF02882.14 EPX73553.1 - 0.012 14.7 0.6 0.053 12.5 0.2 1.9 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EPX73553.1 - 0.019 14.7 0.3 0.071 12.9 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Apolipo_F PF15148.1 EPX73553.1 - 0.082 12.2 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein F Sas10_Utp3 PF04000.10 EPX73554.1 - 3.6e-17 62.3 1.0 5.4e-17 61.7 0.7 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Peptidase_C10 PF01640.12 EPX73554.1 - 0.058 13.1 0.1 0.06 13.0 0.1 1.1 1 0 0 1 1 1 0 Peptidase C10 family DUF4363 PF14276.1 EPX73554.1 - 0.11 12.2 1.7 2.1 8.0 1.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) DUF750 PF04721.12 EPX73554.1 - 0.11 12.5 0.8 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF750) CorA PF01544.13 EPX73554.1 - 0.11 11.4 0.3 0.12 11.4 0.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Aldo_ket_red PF00248.16 EPX73555.1 - 6.1e-29 100.7 0.0 2.1e-25 89.0 0.0 2.9 1 1 2 3 3 3 3 Aldo/keto reductase family TP_methylase PF00590.15 EPX73556.1 - 2.7e-47 161.1 0.0 3.7e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EPX73556.1 - 9.9e-10 38.6 0.0 2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EPX73556.1 - 0.0055 15.9 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal DUF1442 PF07279.6 EPX73556.1 - 0.2 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) DUF2207 PF09972.4 EPX73557.1 - 2.5 6.5 4.7 2.9 6.3 3.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) 7TM_GPCR_Srb PF02175.11 EPX73558.1 - 0.084 12.4 0.9 0.1 12.1 0.7 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srb DUF788 PF05620.6 EPX73560.1 - 0.53 10.1 5.6 0.13 12.1 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF788) DUF2207 PF09972.4 EPX73560.1 - 4.1 5.8 5.0 2.7 6.4 2.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1700 PF08006.6 EPX73561.1 - 3.7 6.8 18.5 7.6 5.7 12.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) Vip3A_N PF12495.3 EPX73562.1 - 0.077 12.6 0.5 12 5.4 0.1 2.2 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal Oxidored_q3 PF00499.15 EPX73562.1 - 0.1 12.3 4.8 0.21 11.3 3.4 1.5 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 SET PF00856.23 EPX73563.1 - 1.2e-12 48.4 0.0 1.5e-11 44.8 0.0 2.2 1 1 0 1 1 1 1 SET domain AAA_12 PF13087.1 EPX73565.1 - 1.8e-38 131.9 0.5 4.3e-38 130.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EPX73565.1 - 3.8e-29 101.9 3.2 4.3e-29 101.7 0.8 2.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPX73565.1 - 8.5e-11 41.4 0.1 3.4e-10 39.5 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPX73565.1 - 1.5e-07 31.2 0.0 3e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EPX73565.1 - 5.4e-05 23.1 0.8 0.00022 21.1 0.5 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EPX73565.1 - 9.9e-05 21.7 3.1 9.9e-05 21.7 2.1 3.2 4 1 0 4 4 4 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 EPX73565.1 - 0.00012 22.1 0.1 0.00048 20.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 EPX73565.1 - 0.00034 19.7 0.5 0.0012 17.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EPX73565.1 - 0.0004 19.6 0.0 0.001 18.3 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.13 EPX73565.1 - 0.0018 17.8 0.0 0.89 9.0 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 EPX73565.1 - 0.0019 17.7 0.8 0.0056 16.1 0.6 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPX73565.1 - 0.0035 17.4 0.0 0.031 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EPX73565.1 - 0.0041 17.3 0.4 0.041 14.0 0.2 2.6 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EPX73565.1 - 0.017 14.4 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EPX73565.1 - 0.021 13.9 0.0 0.062 12.4 0.0 1.8 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EPX73565.1 - 0.034 14.0 0.1 0.2 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EPX73565.1 - 0.049 13.3 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EPX73565.1 - 0.075 12.4 0.2 0.5 9.8 0.1 2.3 1 1 0 1 1 1 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 EPX73565.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Ribosomal_L22 PF00237.14 EPX73566.1 - 5.1e-18 64.9 0.3 7.2e-18 64.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e zf-CCCH PF00642.19 EPX73567.1 - 1.4e-08 34.2 11.3 0.00037 20.0 2.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPX73567.1 - 0.24 11.4 15.7 0.07 13.1 3.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type CUE PF02845.11 EPX73568.1 - 2.5e-07 30.0 0.1 6.8e-07 28.6 0.1 1.8 1 0 0 1 1 1 1 CUE domain Nipped-B_C PF12830.2 EPX73568.1 - 0.0096 15.5 0.2 0.069 12.7 0.0 2.2 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus NTP_transferase PF00483.18 EPX73569.1 - 1.8e-51 174.8 0.0 4.4e-51 173.5 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EPX73569.1 - 3.7e-12 45.1 8.0 2.8e-10 39.2 1.6 3.9 2 2 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EPX73569.1 - 2.1e-11 44.1 0.0 3.9e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EPX73569.1 - 5.7e-06 25.7 2.0 5.7e-06 25.7 1.4 3.4 4 1 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 EPX73569.1 - 0.041 13.3 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase PKD_channel PF08016.7 EPX73570.1 - 0.076 11.4 5.4 0.085 11.2 3.7 1.0 1 0 0 1 1 1 0 Polycystin cation channel Gly_transf_sug PF04488.10 EPX73571.1 - 2.3e-22 79.3 0.0 4.9e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EPX73571.1 - 0.0061 15.0 4.8 0.13 10.7 0.1 2.2 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EPX73571.1 - 0.044 12.9 0.1 0.044 12.9 0.0 1.7 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein PP2C PF00481.16 EPX73573.1 - 2e-74 250.1 0.1 2.7e-74 249.7 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EPX73573.1 - 1.8e-06 27.4 0.1 2.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EPX73573.1 - 0.009 15.7 0.0 0.064 12.9 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) GATA PF00320.22 EPX73574.1 - 7.1e-12 44.4 5.2 1.3e-11 43.6 3.6 1.4 1 0 0 1 1 1 1 GATA zinc finger Terminase_GpA PF05876.7 EPX73574.1 - 0.085 11.2 0.1 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF3414 PF11894.3 EPX73575.1 - 9.8e-173 576.4 38.2 1.3e-172 576.0 26.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Rep_fac_C PF08542.6 EPX73575.1 - 0.013 15.4 0.1 1.3 9.0 0.0 2.9 2 0 0 2 2 2 0 Replication factor C C-terminal domain DUF4328 PF14219.1 EPX73575.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) RNA_pol_Rpc34 PF05158.7 EPX73576.1 - 1.3e-94 317.0 0.0 2.8e-94 315.9 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit z-alpha PF02295.12 EPX73576.1 - 0.0012 18.5 0.0 0.0031 17.2 0.0 1.8 1 0 0 1 1 1 1 Adenosine deaminase z-alpha domain RPA_C PF08784.6 EPX73576.1 - 0.0037 17.6 0.0 0.021 15.2 0.0 2.2 2 1 0 2 2 2 1 Replication protein A C terminal TrmB PF01978.14 EPX73576.1 - 0.0069 16.0 0.1 2.9 7.6 0.0 2.6 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.1 EPX73576.1 - 0.14 11.9 0.7 0.34 10.7 0.0 2.0 3 0 0 3 3 3 0 Winged helix-turn-helix EndIII_4Fe-2S PF10576.4 EPX73576.1 - 0.18 12.0 1.5 0.33 11.1 1.0 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Lyase_1 PF00206.15 EPX73578.1 - 5.8e-111 370.6 0.0 7.9e-111 370.1 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EPX73578.1 - 6.5e-22 77.3 0.0 1.6e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus VWA_2 PF13519.1 EPX73578.1 - 0.089 12.8 0.1 0.73 9.9 0.0 2.1 1 1 1 2 2 2 0 von Willebrand factor type A domain Proteasom_PSMB PF10508.4 EPX73579.1 - 7.9e-08 31.0 0.0 1.9e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT PF02985.17 EPX73579.1 - 0.073 13.1 0.2 19 5.6 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Flavokinase PF01687.12 EPX73580.1 - 4.7e-40 136.3 0.0 5.5e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase WD40 PF00400.27 EPX73581.1 - 4.8e-06 26.2 10.5 0.082 12.8 0.2 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Ribosomal_L10 PF00466.15 EPX73582.1 - 5.3e-27 93.6 0.2 1.2e-26 92.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EPX73582.1 - 7.8e-16 58.2 5.9 7.8e-16 58.2 4.1 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein WD40 PF00400.27 EPX73583.1 - 2.4e-10 39.9 2.0 0.0006 19.6 0.2 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Fcf1 PF04900.7 EPX73584.1 - 2.1e-30 104.8 0.8 3.4e-30 104.1 0.6 1.4 1 0 0 1 1 1 1 Fcf1 Phos_pyr_kin PF08543.7 EPX73585.1 - 2.9e-13 49.5 0.0 4.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EPX73585.1 - 0.0014 17.8 0.0 0.0025 17.0 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase tRNA-synt_2 PF00152.15 EPX73586.1 - 2e-77 260.2 0.0 2.5e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPX73586.1 - 2.5e-10 40.0 0.0 4.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EPX73586.1 - 2.4e-08 33.5 0.1 0.00035 19.8 0.0 3.0 2 1 1 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EPX73586.1 - 0.044 13.3 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Mre11_DNA_bind PF04152.9 EPX73586.1 - 0.065 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain DcpS_C PF11969.3 EPX73587.1 - 9.4e-21 74.2 2.2 1.6e-20 73.5 1.5 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EPX73587.1 - 3.9e-18 65.7 1.9 9.5e-18 64.5 1.3 1.7 1 1 0 1 1 1 1 HIT domain RNA_pol_Rpc4 PF05132.9 EPX73588.1 - 1.8e-29 102.3 0.1 1.8e-29 102.3 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase III RPC4 CAF1 PF04857.15 EPX73589.1 - 1.5e-67 227.7 0.0 2.2e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease RNase_H_2 PF13482.1 EPX73589.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 RNase_H superfamily WD40 PF00400.27 EPX73590.1 - 2.8e-89 290.1 24.1 1.5e-14 53.1 0.1 8.7 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 EPX73590.1 - 9.9e-13 47.9 0.7 1.6e-12 47.2 0.1 1.7 2 0 0 2 2 2 1 NLE (NUC135) domain eIF2A PF08662.6 EPX73590.1 - 3.6e-09 36.6 0.1 0.0016 18.2 0.0 4.0 2 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPX73590.1 - 1.3e-07 30.1 14.7 0.0053 14.9 0.0 5.0 3 3 2 5 5 5 3 Nucleoporin Nup120/160 Gmad1 PF10647.4 EPX73590.1 - 0.0018 17.7 0.6 0.0018 17.7 0.4 1.9 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 EPX73590.1 - 0.032 12.5 0.2 0.094 10.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EPX73590.1 - 0.09 11.5 4.2 0.77 8.4 0.5 3.6 2 2 1 3 3 3 0 Nup133 N terminal like Nbas_N PF15492.1 EPX73590.1 - 0.18 10.8 2.6 2.9 6.8 0.0 3.1 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EPX73590.1 - 0.26 10.9 3.3 16 5.2 0.0 3.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Sec10 PF07393.6 EPX73591.1 - 4.7e-74 249.8 2.6 2.2e-73 247.6 1.8 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EPX73591.1 - 4.8e-06 26.1 0.4 1.8e-05 24.3 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPX73591.1 - 2.8e-05 23.6 1.0 8.3e-05 22.1 0.7 1.9 1 0 0 1 1 1 1 F-box domain R3H PF01424.17 EPX73592.1 - 5.6e-12 45.1 0.0 1.1e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EPX73592.1 - 2e-07 30.8 192.0 0.0048 16.8 8.1 12.3 12 0 0 12 12 12 8 NF-X1 type zinc finger MFS_1 PF07690.11 EPX73593.1 - 2.7e-53 180.9 28.0 1.7e-48 165.1 16.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EPX73593.1 - 1.6 6.6 10.1 4.9 5.0 0.1 2.7 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SUN PF03856.8 EPX73594.1 - 1.4e-74 250.5 12.9 3e-74 249.4 8.9 1.5 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Ribosomal_S2 PF00318.15 EPX73595.1 - 1.5e-30 106.0 0.1 1e-19 70.6 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 Lon_2 PF13337.1 EPX73595.1 - 0.14 10.4 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease HisKA PF00512.20 EPX73596.1 - 1.4e-16 60.2 0.7 3.1e-16 59.1 0.0 2.0 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EPX73596.1 - 1.2e-15 57.4 0.0 5.9e-15 55.2 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain GAF_2 PF13185.1 EPX73596.1 - 4.3e-09 37.0 0.0 9.7e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EPX73596.1 - 6.9e-09 35.8 0.0 2e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EPX73596.1 - 4.2e-08 32.6 0.3 2.2e-07 30.2 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain AAA_16 PF13191.1 EPX73596.1 - 5.1e-08 33.1 0.0 1.5e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PAS_3 PF08447.6 EPX73596.1 - 2.1e-07 30.9 0.0 5.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold Pkinase_Tyr PF07714.12 EPX73596.1 - 4e-05 22.8 0.0 0.00011 21.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase HATPase_c PF02518.21 EPX73596.1 - 0.00033 20.3 0.0 0.00081 19.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_11 PF13414.1 EPX73596.1 - 0.0031 17.1 3.7 0.08 12.5 1.3 3.5 3 0 0 3 3 3 1 TPR repeat PAS_9 PF13426.1 EPX73596.1 - 0.029 14.7 0.0 0.084 13.2 0.0 1.8 1 0 0 1 1 1 0 PAS domain AAA_17 PF13207.1 EPX73596.1 - 0.085 13.6 0.0 0.65 10.8 0.0 2.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EPX73596.1 - 0.11 12.1 0.1 0.33 10.6 0.0 1.8 2 0 0 2 2 1 0 NTPase Ribosomal_L27e PF01777.13 EPX73597.1 - 2.9e-37 126.6 1.7 4e-37 126.2 1.2 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EPX73597.1 - 0.0004 20.0 1.1 0.00056 19.5 0.0 1.9 2 0 0 2 2 2 1 KOW motif AA_permease_2 PF13520.1 EPX73598.1 - 2e-64 217.7 44.6 2.5e-64 217.3 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPX73598.1 - 2.4e-21 75.6 37.4 3.2e-21 75.2 25.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1378 PF07125.6 EPX73598.1 - 0.099 12.6 0.2 0.23 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Ammonium_transp PF00909.16 EPX73599.1 - 3.5e-117 391.2 24.0 4e-117 391.0 16.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family EamA PF00892.15 EPX73599.1 - 0.0054 16.7 1.8 0.0054 16.7 1.2 3.9 3 1 1 4 4 4 1 EamA-like transporter family UPF0270 PF06794.7 EPX73600.1 - 0.017 14.8 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) AA_permease PF00324.16 EPX73601.1 - 3.4e-104 348.8 32.6 3.9e-104 348.6 22.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPX73601.1 - 4.5e-39 134.2 37.3 5.4e-39 133.9 25.9 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EPX73602.1 - 6.3e-20 71.1 23.8 1.1e-19 70.4 16.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily PspB PF06667.7 EPX73602.1 - 0.21 11.5 0.0 0.21 11.5 0.0 2.5 3 0 0 3 3 3 0 Phage shock protein B TauD PF02668.11 EPX73603.1 - 1.3e-40 139.6 1.2 3e-40 138.5 0.8 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EPX73603.1 - 0.0092 16.4 0.0 1.8 9.1 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Asp_Glu_race PF01177.17 EPX73604.1 - 1.8e-28 99.9 0.4 2.1e-28 99.7 0.3 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase FLO_LFY PF01698.11 EPX73604.1 - 0.026 13.3 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein AhpC-TSA PF00578.16 EPX73605.1 - 9.9e-39 131.8 0.0 1.3e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPX73605.1 - 1.1e-17 63.9 0.0 1.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EPX73605.1 - 8.3e-10 38.1 0.0 1.8e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin LSM PF01423.17 EPX73606.1 - 5.6e-06 25.8 0.0 6.5e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain Gemin6 PF06372.7 EPX73606.1 - 0.01 15.1 0.0 0.011 15.1 0.0 1.0 1 0 0 1 1 1 0 Gemin6 protein zf-CHC2 PF01807.15 EPX73606.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 CHC2 zinc finger Bax1-I PF01027.15 EPX73607.1 - 4.2e-46 157.1 29.1 5.1e-46 156.8 20.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SAC3_GANP PF03399.11 EPX73608.1 - 7.3e-57 192.2 1.6 1.4e-56 191.3 1.1 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPX73608.1 - 1.7e-05 24.6 2.3 2.5e-05 24.0 0.0 2.4 3 0 0 3 3 3 1 COP9 signalosome, subunit CSN8 PAM2 PF07145.10 EPX73608.1 - 0.00022 20.5 1.0 0.00054 19.2 0.7 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region tRNA-synt_1b PF00579.20 EPX73609.1 - 3.4e-73 246.3 0.0 4.4e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 EPX73609.1 - 0.00031 20.1 0.0 0.00063 19.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain Cactin_mid PF10312.4 EPX73609.1 - 0.025 13.8 0.1 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Conserved mid region of cactin Clat_adaptor_s PF01217.15 EPX73610.1 - 6.2e-13 48.6 0.1 8.5e-13 48.2 0.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain P53_tetramer PF07710.6 EPX73610.1 - 0.036 13.1 0.1 0.068 12.2 0.1 1.4 1 0 0 1 1 1 0 P53 tetramerisation motif Ribosomal_S5 PF00333.15 EPX73611.1 - 3e-28 97.3 2.4 4.5e-28 96.7 0.7 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EPX73611.1 - 3e-21 74.4 0.1 5.6e-21 73.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.1 EPX73611.1 - 5.1 7.6 6.7 11 6.5 4.7 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_S10 PF00338.17 EPX73612.1 - 9.8e-32 108.6 1.0 1.5e-31 108.1 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF4469 PF14734.1 EPX73612.1 - 0.059 13.2 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold AAA PF00004.24 EPX73613.1 - 1.4e-44 151.4 0.0 3.3e-44 150.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPX73613.1 - 2.7e-08 33.6 0.1 9.3e-08 31.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPX73613.1 - 1.7e-07 31.4 0.0 6.5e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EPX73613.1 - 3e-07 30.5 0.0 9e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EPX73613.1 - 2.7e-06 27.5 0.1 0.0008 19.5 0.0 2.6 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 EPX73613.1 - 3.2e-06 26.2 0.0 4.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EPX73613.1 - 2.5e-05 23.4 0.0 5.7e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EPX73613.1 - 0.00035 20.5 0.0 0.0007 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EPX73613.1 - 0.00042 19.9 0.0 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EPX73613.1 - 0.00049 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPX73613.1 - 0.00058 19.5 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EPX73613.1 - 0.00069 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPX73613.1 - 0.00095 19.9 0.0 0.0027 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EPX73613.1 - 0.001 18.7 0.0 0.038 13.6 0.0 2.8 3 0 0 3 3 2 1 NACHT domain RNA_helicase PF00910.17 EPX73613.1 - 0.0014 18.8 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 EPX73613.1 - 0.0015 18.2 0.1 0.0052 16.4 0.1 2.0 1 1 0 1 1 1 1 NTPase Zeta_toxin PF06414.7 EPX73613.1 - 0.0016 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 EPX73613.1 - 0.0026 16.5 0.0 0.0061 15.3 0.0 1.5 1 1 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EPX73613.1 - 0.0029 17.0 1.0 0.061 12.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain T2SE PF00437.15 EPX73613.1 - 0.003 16.5 0.0 0.0073 15.2 0.0 1.6 1 1 0 1 1 1 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 EPX73613.1 - 0.0046 16.1 0.1 0.013 14.6 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 EPX73613.1 - 0.0067 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Bac_DnaA PF00308.13 EPX73613.1 - 0.0095 15.5 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_11 PF13086.1 EPX73613.1 - 0.01 15.3 0.0 0.035 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EPX73613.1 - 0.011 15.1 0.0 0.036 13.4 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 EPX73613.1 - 0.014 15.1 0.0 0.078 12.6 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 EPX73613.1 - 0.016 14.8 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPX73613.1 - 0.023 14.5 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 EPX73613.1 - 0.045 12.5 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase KaiC PF06745.8 EPX73613.1 - 0.066 12.3 0.2 0.86 8.6 0.0 2.6 3 0 0 3 3 3 0 KaiC NB-ARC PF00931.17 EPX73613.1 - 0.076 11.8 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.21 EPX73613.1 - 0.078 12.4 0.2 1.4 8.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_18 PF13238.1 EPX73613.1 - 0.094 13.0 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EPX73613.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 EPX73613.1 - 0.13 12.6 0.1 0.53 10.5 0.0 2.3 2 1 0 2 2 2 0 ABC transporter Ribosomal_L15e PF00827.12 EPX73614.1 - 7.3e-80 267.0 8.5 8.8e-80 266.7 5.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L15e PF00827.12 EPX73615.1 - 4.3e-89 297.1 9.0 5.1e-89 296.8 6.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 CENP-X PF09415.5 EPX73616.1 - 3.1e-22 78.1 0.2 3.7e-22 77.9 0.1 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X BCNT PF07572.7 EPX73617.1 - 1.4e-17 63.3 4.6 4.1e-17 61.8 3.2 1.8 1 0 0 1 1 1 1 Bucentaur or craniofacial development SCHIP-1 PF10148.4 EPX73617.1 - 4.1 6.7 8.4 0.82 9.0 2.0 2.1 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 Menin PF05053.8 EPX73617.1 - 8 4.4 14.5 9.2 4.2 10.0 1.1 1 0 0 1 1 1 0 Menin TP_methylase PF00590.15 EPX73618.1 - 2.3e-20 73.1 0.0 3.8e-20 72.5 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pkinase PF00069.20 EPX73619.1 - 2.6e-66 223.4 0.0 3.5e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73619.1 - 2.6e-31 108.6 0.0 3.9e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.1 EPX73619.1 - 2e-06 27.5 0.3 1.4e-05 24.9 0.0 2.5 2 1 0 2 2 2 1 PH domain Kdo PF06293.9 EPX73619.1 - 0.00017 20.7 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX73619.1 - 0.00023 20.9 0.0 0.00053 19.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPX73619.1 - 0.0011 17.9 0.0 0.0031 16.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EPX73619.1 - 0.0055 16.0 0.4 0.012 15.0 0.2 1.5 1 1 0 1 1 1 1 RIO1 family LSM PF01423.17 EPX73620.1 - 3.4e-15 55.3 0.2 4.2e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPX73620.1 - 0.0081 16.0 0.0 0.0099 15.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1461 PF07314.6 EPX73620.1 - 0.12 12.0 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) SRP19 PF01922.12 EPX73621.1 - 7.6e-22 77.7 0.2 1.1e-21 77.1 0.1 1.3 1 0 0 1 1 1 1 SRP19 protein SAP18 PF06487.7 EPX73622.1 - 1.2e-21 76.6 0.0 1.5e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.10 EPX73623.1 - 2.6e-45 153.8 1.7 2.8e-45 153.6 0.0 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EPX73623.1 - 4.4e-10 38.6 0.6 4.4e-10 38.6 0.4 2.2 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like DUF2215 PF10225.4 EPX73623.1 - 4.7 6.5 4.7 8.7 5.7 3.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) NIF3 PF01784.13 EPX73624.1 - 5e-68 229.2 0.0 6e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RRM_1 PF00076.17 EPX73625.1 - 1.5e-08 34.0 0.0 2.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX73625.1 - 0.0017 18.1 0.1 0.0027 17.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX73625.1 - 0.004 17.1 0.0 0.0062 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPX73625.1 - 0.091 12.6 0.4 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 RNA binding motif Lipase_GDSL_2 PF13472.1 EPX73626.1 - 8.7e-21 74.8 0.0 1e-20 74.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPX73626.1 - 4.6e-15 56.0 0.0 6.1e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EPX73626.1 - 0.063 13.0 0.0 0.083 12.6 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Zip PF02535.17 EPX73627.1 - 1.7e-40 138.9 12.9 2.2e-40 138.6 8.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Lectin_leg-like PF03388.8 EPX73628.1 - 1.1e-69 234.0 0.0 1.4e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EPX73628.1 - 1.2e-05 24.8 0.2 2.3e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 Legume lectin domain PHD PF00628.24 EPX73629.1 - 4.1e-11 42.3 4.9 4.1e-11 42.3 3.4 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EPX73629.1 - 9.8e-10 38.1 27.1 5.2e-08 32.6 9.3 3.2 2 1 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 EPX73629.1 - 1.4e-09 37.8 5.4 1.4e-09 37.8 3.8 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPX73629.1 - 2.2e-05 24.3 3.5 2.2e-05 24.3 2.4 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX73629.1 - 3.5e-05 23.3 8.0 3.5e-05 23.3 5.6 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX73629.1 - 0.00026 20.5 8.3 0.00026 20.5 5.8 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EPX73629.1 - 0.0013 18.0 1.0 0.0035 16.6 0.7 1.8 1 0 0 1 1 1 1 PHD-finger zf-Apc11 PF12861.2 EPX73629.1 - 0.0033 17.2 1.1 0.0033 17.2 0.7 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-PHD-like PF15446.1 EPX73629.1 - 0.014 14.6 1.3 0.014 14.6 0.9 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_5 PF14634.1 EPX73629.1 - 0.9 9.3 21.4 0.018 14.7 5.8 2.8 2 1 0 2 2 2 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.1 EPX73629.1 - 2.5 8.1 8.4 0.36 10.8 0.4 2.6 2 1 0 2 2 2 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.1 EPX73629.1 - 4.7 7.0 11.8 0.059 13.1 0.8 2.9 2 1 1 3 3 2 0 Prokaryotic RING finger family 1 Cofilin_ADF PF00241.15 EPX73630.1 - 4.3e-21 75.1 5.0 6.1e-10 39.0 0.3 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein PDT PF00800.13 EPX73630.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydratase MRP-L46 PF11788.3 EPX73631.1 - 2.2e-21 76.5 0.0 3.9e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EPX73631.1 - 0.0079 15.8 0.1 0.026 14.1 0.1 1.9 2 1 0 2 2 2 1 NUDIX domain SCA7 PF08313.7 EPX73632.1 - 5.9e-32 109.0 2.1 5.9e-32 109.0 1.5 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain zf-C2HC_2 PF13913.1 EPX73632.1 - 0.0054 16.3 0.1 0.0094 15.5 0.0 1.4 1 0 0 1 1 1 1 zinc-finger of a C2HC-type DUF1292 PF06949.6 EPX73632.1 - 0.013 15.8 0.1 0.031 14.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1292) Sgf11 PF08209.6 EPX73632.1 - 0.048 12.9 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) PseudoU_synth_1 PF01416.15 EPX73633.1 - 1.9e-19 70.0 0.0 1e-08 35.5 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase DEADboxA PF12343.3 EPX73633.1 - 0.056 13.6 1.7 0.12 12.6 1.2 1.4 1 0 0 1 1 1 0 Cold shock protein DEAD box A Pec_lyase_N PF04431.8 EPX73633.1 - 0.13 12.4 1.6 0.44 10.6 1.1 1.9 1 0 0 1 1 1 0 Pectate lyase, N terminus Ku_N PF03731.10 EPX73634.1 - 2.5e-50 171.0 0.1 2.5e-50 171.0 0.1 1.6 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 EPX73634.1 - 1.3e-42 145.4 0.0 2.9e-42 144.3 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.9 EPX73634.1 - 1.3e-15 57.6 1.2 3.2e-15 56.4 0.8 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EPX73634.1 - 1.5e-10 40.3 0.4 3.5e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.1 EPX73634.1 - 3.4e-05 24.0 0.0 5.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain HeH PF12949.2 EPX73634.1 - 0.01 15.3 0.6 0.05 13.1 0.4 2.2 1 1 0 1 1 1 0 HeH/LEM domain WD40 PF00400.27 EPX73635.1 - 8.3e-32 107.9 9.4 2e-05 24.2 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EPX73635.1 - 7.2e-06 24.4 6.4 0.52 8.3 0.1 4.3 3 2 0 4 4 4 3 Nucleoporin Nup120/160 Peptidase_M7 PF02031.11 EPX73635.1 - 0.038 13.7 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family MFS_1 PF07690.11 EPX73636.1 - 3.1e-25 88.6 41.4 6.5e-23 81.0 19.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX73636.1 - 5.7e-07 28.4 10.0 5.7e-07 28.4 6.9 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter DUF4229 PF14012.1 EPX73636.1 - 1.8 8.5 5.9 0.86 9.5 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) WD40 PF00400.27 EPX73638.1 - 5.3e-18 64.1 5.9 0.00021 21.0 0.0 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EPX73638.1 - 9.7e-07 28.6 3.5 0.0077 15.9 0.0 4.3 1 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 EPX73638.1 - 0.034 13.8 1.3 0.076 12.7 0.0 2.3 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 EPX73638.1 - 0.074 10.8 0.1 0.19 9.4 0.0 1.7 1 1 1 2 2 2 0 IKI3 family PPTA PF01239.17 EPX73639.1 - 1.6e-44 147.4 19.0 1.8e-08 33.3 0.2 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Pribosyltran_N PF13793.1 EPX73640.1 - 3.6e-49 165.3 0.3 2.4e-47 159.4 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EPX73640.1 - 5.7e-44 150.0 5.3 1.3e-37 129.3 1.7 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EPX73640.1 - 4.9e-12 45.6 1.7 7.7e-12 45.0 0.5 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPX73640.1 - 0.0099 15.1 0.1 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase TgMIC1 PF11476.3 EPX73640.1 - 0.099 12.1 0.2 0.44 10.0 0.1 2.1 3 0 0 3 3 3 0 Toxoplasma gondii micronemal protein 1 TgMIC1 DUF2296 PF10058.4 EPX73641.1 - 4e-21 74.5 0.7 7.5e-21 73.6 0.5 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) UPF0104 PF03706.8 EPX73641.1 - 0.0042 16.4 0.4 0.0063 15.8 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) DUF485 PF04341.7 EPX73641.1 - 0.045 13.4 0.2 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 TSP9 PF11493.3 EPX73641.1 - 0.055 14.0 0.5 0.11 13.0 0.3 1.5 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 ATP-grasp_2 PF08442.5 EPX73642.1 - 7.7e-75 250.7 0.0 1.2e-74 250.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EPX73642.1 - 2.5e-23 82.3 0.2 3.9e-23 81.7 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EPX73642.1 - 1.4e-05 24.4 0.0 3.6e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EPX73642.1 - 0.045 13.3 0.0 0.13 11.8 0.0 1.8 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TFIIF_alpha PF05793.7 EPX73643.1 - 6e-19 67.8 18.9 4.1e-11 41.9 0.8 2.7 3 0 0 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Vac7 PF12751.2 EPX73643.1 - 0.00034 19.5 0.1 0.0006 18.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 Bud13 PF09736.4 EPX73644.1 - 2.9e-44 150.8 9.7 2.9e-44 150.8 6.8 2.9 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex DUF4346 PF14251.1 EPX73644.1 - 0.4 10.4 5.1 0.21 11.3 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4346) Nic96 PF04097.9 EPX73645.1 - 3.7e-181 603.3 0.3 4.9e-181 602.9 0.2 1.1 1 0 0 1 1 1 1 Nup93/Nic96 RabGAP-TBC PF00566.13 EPX73646.1 - 7.8e-14 51.6 0.1 7.8e-14 51.6 0.1 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain IncA PF04156.9 EPX73646.1 - 0.0026 17.3 21.4 0.15 11.6 14.8 2.6 1 1 0 1 1 1 1 IncA protein Laminin_I PF06008.9 EPX73646.1 - 0.0056 16.0 14.3 0.0068 15.7 9.3 1.6 1 1 0 1 1 1 1 Laminin Domain I Toxin_10 PF05431.6 EPX73646.1 - 0.025 14.2 0.3 0.025 14.2 0.2 1.8 2 0 0 2 2 2 0 Insecticidal Crystal Toxin, P42 DUF2968 PF11180.3 EPX73646.1 - 0.035 13.4 12.7 0.033 13.5 7.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) Tropomyosin_1 PF12718.2 EPX73646.1 - 0.43 10.4 20.1 1.1 9.0 13.9 1.8 1 0 0 1 1 1 0 Tropomyosin like V_ATPase_I PF01496.14 EPX73646.1 - 1.3 6.7 10.3 2 6.1 7.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.9 EPX73646.1 - 2.2 7.8 14.8 2.1 7.9 5.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Prefoldin_2 PF01920.15 EPX73646.1 - 2.9 7.6 20.4 1.7 8.4 1.8 3.5 1 1 2 3 3 3 0 Prefoldin subunit DUF948 PF06103.6 EPX73646.1 - 3.5 7.5 9.0 1.7 8.5 0.9 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Cep57_CLD_2 PF14197.1 EPX73646.1 - 9.1 6.3 19.7 0.54 10.2 4.0 2.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 His_Phos_1 PF00300.17 EPX73647.1 - 3.5e-25 88.9 0.0 5.6e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TroA PF01297.12 EPX73647.1 - 0.036 13.3 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Periplasmic solute binding protein family SNF2_N PF00176.18 EPX73648.1 - 1.6e-76 256.9 0.2 1.6e-76 256.9 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EPX73648.1 - 9.2e-20 70.3 0.1 3.3e-19 68.5 0.0 2.0 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 EPX73648.1 - 6.8e-18 64.3 0.3 2.7e-16 59.1 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SnAC PF14619.1 EPX73648.1 - 3.3e-09 36.7 0.6 1.6e-08 34.6 0.4 2.3 1 0 0 1 1 1 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.10 EPX73648.1 - 7.9e-08 32.3 0.4 4.5e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit QLQ PF08880.6 EPX73648.1 - 1.3e-07 30.9 1.5 3.2e-07 29.6 1.1 1.8 1 0 0 1 1 1 1 QLQ HSA PF07529.8 EPX73648.1 - 6e-05 22.7 11.7 0.00012 21.7 6.2 2.7 3 0 0 3 3 3 1 HSA 2C_adapt PF08793.5 EPX73648.1 - 0.063 13.1 0.2 0.24 11.3 0.1 2.1 1 0 0 1 1 1 0 2-cysteine adaptor domain ABC_membrane PF00664.18 EPX73649.1 - 1.1e-35 123.4 9.6 2e-35 122.5 6.7 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EPX73649.1 - 5.6e-32 110.8 0.0 9.8e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EPX73649.1 - 4.5e-07 29.3 0.1 5.4e-06 25.8 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPX73649.1 - 3.1e-06 27.3 0.1 0.00028 20.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPX73649.1 - 0.0017 18.3 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPX73649.1 - 0.004 17.3 0.1 0.026 14.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPX73649.1 - 0.011 14.9 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EPX73649.1 - 0.015 15.1 0.1 0.11 12.3 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EPX73649.1 - 0.019 14.4 0.1 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EPX73649.1 - 0.083 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EPX73649.1 - 0.091 12.1 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EPX73649.1 - 0.14 12.9 0.0 0.52 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPX73650.1 - 1.1e-125 413.9 0.0 1.9e-21 76.2 0.0 10.3 10 0 0 10 10 10 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPX73650.1 - 6.6e-32 109.8 0.0 2.1e-08 33.8 0.0 7.5 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EPX73650.1 - 3.4e-31 108.1 0.5 1.7e-05 25.0 0.0 8.1 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPX73650.1 - 1.2e-19 71.3 7.7 0.0016 19.2 0.0 8.3 7 0 0 7 7 6 5 AAA domain AAA_16 PF13191.1 EPX73650.1 - 3.4e-19 69.5 3.6 0.0027 17.7 0.0 7.6 7 0 0 7 7 6 4 AAA ATPase domain AAA_22 PF13401.1 EPX73650.1 - 4e-19 69.0 6.7 0.0088 16.1 0.0 8.8 7 1 0 7 7 7 4 AAA domain AAA_14 PF13173.1 EPX73650.1 - 1.1e-18 67.3 0.0 8e-05 22.5 0.0 7.8 6 1 0 6 6 6 3 AAA domain AAA_33 PF13671.1 EPX73650.1 - 4.1e-17 62.3 0.0 0.11 12.4 0.0 7.3 6 1 0 6 6 6 4 AAA domain Sigma54_activ_2 PF14532.1 EPX73650.1 - 2.6e-15 56.6 0.1 0.00097 19.1 0.0 6.6 5 0 0 5 5 5 3 Sigma-54 interaction domain Zeta_toxin PF06414.7 EPX73650.1 - 1.3e-14 53.8 0.0 0.11 11.6 0.0 7.0 6 0 0 6 6 6 2 Zeta toxin T2SE PF00437.15 EPX73650.1 - 6.1e-14 51.5 1.0 0.0029 16.5 0.1 6.0 6 0 0 6 6 6 3 Type II/IV secretion system protein AAA_19 PF13245.1 EPX73650.1 - 7.5e-14 51.2 3.9 0.13 12.0 0.0 6.4 6 0 0 6 6 6 3 Part of AAA domain Sigma54_activat PF00158.21 EPX73650.1 - 2.6e-13 49.7 0.0 0.068 12.6 0.0 6.1 6 0 0 6 6 5 3 Sigma-54 interaction domain AAA_18 PF13238.1 EPX73650.1 - 2.7e-11 43.8 32.2 0.003 17.8 0.0 9.0 8 1 0 8 8 6 4 AAA domain RNA_helicase PF00910.17 EPX73650.1 - 8.5e-11 41.9 2.5 0.38 10.9 0.0 7.4 7 0 0 7 7 7 2 RNA helicase AAA_25 PF13481.1 EPX73650.1 - 3.1e-10 39.7 2.2 0.042 13.2 0.0 6.1 6 0 0 6 6 6 2 AAA domain MobB PF03205.9 EPX73650.1 - 3.9e-10 39.5 1.7 0.2 11.3 0.0 6.5 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EPX73650.1 - 4.2e-10 39.2 1.9 0.11 12.1 0.0 6.3 7 0 0 7 7 6 2 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 EPX73650.1 - 5.6e-09 36.5 1.5 3.1 8.3 0.0 6.6 6 0 0 6 6 6 1 Miro-like protein ABC_tran PF00005.22 EPX73650.1 - 6e-09 36.3 21.2 0.0032 17.7 0.0 7.7 8 0 0 8 8 6 2 ABC transporter AAA_29 PF13555.1 EPX73650.1 - 7.5e-09 34.9 0.1 1 8.9 0.1 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain SRP54 PF00448.17 EPX73650.1 - 1.2e-08 34.6 1.7 0.21 10.9 0.2 5.4 5 0 0 5 5 5 2 SRP54-type protein, GTPase domain IstB_IS21 PF01695.12 EPX73650.1 - 1.4e-08 34.3 0.2 0.38 10.1 0.0 5.9 6 1 1 7 7 7 2 IstB-like ATP binding protein NACHT PF05729.7 EPX73650.1 - 2.2e-08 33.9 5.6 0.84 9.2 0.0 5.6 5 0 0 5 5 5 3 NACHT domain Mg_chelatase PF01078.16 EPX73650.1 - 2.2e-08 33.5 4.3 1.5 7.9 0.0 8.7 10 1 0 10 10 9 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EPX73650.1 - 2.4e-08 33.3 3.8 0.061 12.3 0.0 6.1 7 0 0 7 7 7 2 Holliday junction DNA helicase ruvB N-terminus DUF258 PF03193.11 EPX73650.1 - 6.2e-08 31.9 3.1 0.62 9.2 0.0 5.6 6 0 0 6 6 6 2 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EPX73650.1 - 1.1e-07 31.4 3.0 0.046 13.1 0.0 5.5 5 0 0 5 5 5 2 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EPX73650.1 - 7.9e-06 25.9 15.1 0.15 12.0 0.0 7.1 7 0 0 7 7 6 1 AAA domain NTPase_1 PF03266.10 EPX73650.1 - 0.00058 19.6 5.6 17 5.0 0.0 5.2 5 0 0 5 5 5 0 NTPase AAA_6 PF12774.2 EPX73650.1 - 0.0015 18.0 0.0 2.8 7.4 0.0 4.3 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region D1 MMR_HSR1 PF01926.18 EPX73650.1 - 0.0052 16.7 3.9 13 5.7 0.0 5.7 6 0 0 6 6 5 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EPX73650.1 - 0.11 11.9 7.1 2.9 7.3 0.1 4.6 6 0 0 6 6 4 0 FtsK/SpoIIIE family DBI_PRT PF02277.12 EPX73650.1 - 1.3 8.0 0.1 9 5.2 0.1 2.1 2 0 0 2 2 2 0 Phosphoribosyltransferase AAA_12 PF13087.1 EPX73651.1 - 1.1e-57 194.6 0.0 2.4e-57 193.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPX73651.1 - 1.4e-55 188.4 0.0 2.6e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPX73651.1 - 4.2e-12 45.6 0.2 3.6e-11 42.6 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EPX73651.1 - 1.9e-11 43.9 0.0 1.1e-06 28.4 0.0 3.0 3 1 1 4 4 4 2 AAA domain ResIII PF04851.10 EPX73651.1 - 1.1e-06 28.6 0.0 6.1e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EPX73651.1 - 2.2e-06 26.9 0.0 6.4e-06 25.3 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EPX73651.1 - 2.9e-06 26.9 0.4 0.19 11.2 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EPX73651.1 - 2.5e-05 23.7 0.0 6.1e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 EPX73651.1 - 7.7e-05 22.8 0.0 0.011 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPX73651.1 - 0.00097 19.1 0.0 0.0045 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain UvrD_C PF13361.1 EPX73651.1 - 0.0019 17.7 0.4 0.14 11.5 0.0 3.2 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 EPX73651.1 - 0.0022 17.2 0.0 1.2 8.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Zot PF05707.7 EPX73651.1 - 0.0033 16.9 0.2 0.02 14.3 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.12 EPX73651.1 - 0.004 16.5 0.0 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Helicase_RecD PF05127.9 EPX73651.1 - 0.0042 16.7 0.0 0.71 9.4 0.0 2.4 2 0 0 2 2 2 1 Helicase CbiA PF01656.18 EPX73651.1 - 0.0045 16.4 0.1 0.016 14.6 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.24 EPX73651.1 - 0.0075 16.4 0.6 0.043 14.0 0.2 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EPX73651.1 - 0.013 14.9 0.0 0.11 11.9 0.0 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.4 EPX73651.1 - 0.015 13.9 0.0 0.029 12.9 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 EPX73651.1 - 0.016 14.9 0.0 0.048 13.3 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 4HB_MCP_1 PF12729.2 EPX73651.1 - 0.021 14.2 1.7 0.063 12.6 0.2 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction PIF1 PF05970.9 EPX73651.1 - 0.033 13.1 0.4 1.1 8.1 0.0 3.2 4 0 0 4 4 4 0 PIF1-like helicase AAA_5 PF07728.9 EPX73651.1 - 0.036 13.7 0.0 0.097 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EPX73651.1 - 0.036 12.9 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Birna_VP5 PF03042.9 EPX73651.1 - 0.038 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 Birnavirus VP5 protein NTPase_1 PF03266.10 EPX73651.1 - 0.045 13.4 0.4 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.1 EPX73651.1 - 0.062 12.6 0.0 0.4 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EPX73651.1 - 0.098 13.4 0.9 0.64 10.8 0.2 2.7 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.9 EPX73651.1 - 0.11 12.2 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Flavivirus DEAD domain SRP54 PF00448.17 EPX73651.1 - 0.12 11.8 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Aldo_ket_red PF00248.16 EPX73652.1 - 7.9e-05 21.6 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Pex24p PF06398.6 EPX73653.1 - 9.6e-12 44.3 20.5 1.1e-07 30.9 1.4 3.0 1 1 2 3 3 3 3 Integral peroxisomal membrane peroxin DUF2238 PF09997.4 EPX73653.1 - 0.29 10.5 3.0 0.42 10.0 1.7 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2238) Cys_Met_Meta_PP PF01053.15 EPX73654.1 - 1.1e-122 409.0 0.0 1.2e-122 408.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPX73654.1 - 1e-06 28.0 0.0 1.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 EPX73654.1 - 0.0037 15.6 0.0 0.0065 14.8 0.0 1.4 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EPX73654.1 - 0.0057 15.3 0.0 0.0092 14.7 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EPX73654.1 - 0.016 13.9 0.0 0.028 13.1 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPX73654.1 - 0.023 13.7 0.0 0.056 12.4 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Peptidase_C13 PF01650.13 EPX73655.1 - 1.8e-39 135.5 0.3 2.3e-39 135.2 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family Dynamitin PF04912.9 EPX73656.1 - 1.2e-12 47.3 8.6 3.9e-09 35.7 1.7 2.7 2 1 0 2 2 2 2 Dynamitin CorA PF01544.13 EPX73656.1 - 0.15 11.0 2.7 2.9 6.8 0.1 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1539 PF07560.6 EPX73656.1 - 0.39 10.5 6.6 0.093 12.6 1.2 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) Spectrin PF00435.16 EPX73656.1 - 0.42 10.9 0.1 0.42 10.9 0.0 3.4 3 1 0 3 3 3 0 Spectrin repeat XPG_I PF00867.13 EPX73657.1 - 2.5e-20 72.3 0.0 5.7e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EPX73657.1 - 7.9e-06 26.0 0.0 7.2e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 XPG N-terminal domain ATP13 PF12921.2 EPX73658.1 - 1.3e-25 89.1 0.2 1e-24 86.2 0.0 2.5 3 0 0 3 3 3 1 Mitochondrial ATPase expression PPR PF01535.15 EPX73658.1 - 0.003 17.4 0.0 0.21 11.6 0.0 2.9 3 0 0 3 3 3 1 PPR repeat DUF2982 PF11201.3 EPX73658.1 - 0.013 14.8 0.1 0.025 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) PPR_1 PF12854.2 EPX73658.1 - 0.016 14.6 0.0 0.043 13.3 0.0 1.7 1 0 0 1 1 1 0 PPR repeat DUF1542 PF07564.6 EPX73658.1 - 0.1 12.6 1.1 1.5 8.9 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) GDA1_CD39 PF01150.12 EPX73659.1 - 1.6e-106 356.4 0.0 1.9e-106 356.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PsbI PF02532.9 EPX73659.1 - 0.036 13.6 1.9 0.074 12.6 1.3 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) PAXNEB PF05625.6 EPX73660.1 - 3.9e-94 315.4 0.0 4.3e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein IF-2B PF01008.12 EPX73661.1 - 1.5e-65 221.0 0.0 2.1e-65 220.5 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family CPSF_A PF03178.10 EPX73662.1 - 4.9e-19 68.5 3.5 2.1e-18 66.5 0.4 2.7 2 0 0 2 2 2 1 CPSF A subunit region ECR1_N PF14382.1 EPX73662.1 - 0.084 12.1 0.0 0.21 10.8 0.0 1.8 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Alpha-amylase PF00128.19 EPX73663.1 - 1.4e-65 221.7 0.5 1.9e-65 221.3 0.3 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EPX73663.1 - 0.00034 20.6 0.0 0.00073 19.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF187 PF02638.10 EPX73663.1 - 0.00049 19.0 0.3 0.00084 18.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 hDGE_amylase PF14701.1 EPX73663.1 - 0.0075 15.2 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Aminotran_5 PF00266.14 EPX73663.1 - 0.082 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V B56 PF01603.15 EPX73664.1 - 2.4e-158 527.0 5.9 3.2e-158 526.6 4.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.2 EPX73664.1 - 0.0031 16.9 7.2 0.031 13.7 0.3 3.1 2 1 1 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF2122 PF09895.4 EPX73664.1 - 0.0063 16.7 0.7 0.024 14.8 0.0 2.2 2 0 0 2 2 2 1 RecB-family nuclease (DUF2122) Cnd3 PF12719.2 EPX73665.1 - 1.2e-77 260.8 3.2 1.2e-77 260.8 2.2 2.4 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EPX73665.1 - 3.7e-09 36.7 4.4 1.4e-05 25.2 0.1 4.0 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EPX73665.1 - 9.4e-05 22.1 6.4 1.1 9.5 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EPX73665.1 - 0.049 14.1 5.6 0.62 10.6 0.4 4.5 3 1 1 4 4 4 0 HEAT-like repeat SRP54 PF00448.17 EPX73666.1 - 3.5e-80 268.0 1.7 2.5e-79 265.3 0.5 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EPX73666.1 - 3.8e-23 81.7 4.4 3.8e-23 81.7 3.0 3.4 2 1 1 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.14 EPX73666.1 - 7.2e-16 58.0 0.8 1.5e-15 57.0 0.6 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 EPX73666.1 - 9.8e-08 31.9 0.1 3.8e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EPX73666.1 - 3.2e-07 29.9 1.3 2.1e-06 27.2 0.9 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 EPX73666.1 - 8.8e-06 25.2 0.1 3.1e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 EPX73666.1 - 1.5e-05 24.1 0.2 3.2e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin ArgK PF03308.11 EPX73666.1 - 5.4e-05 22.0 0.4 0.0028 16.4 0.0 2.3 2 0 0 2 2 2 1 ArgK protein MobB PF03205.9 EPX73666.1 - 0.00013 21.6 0.1 0.00035 20.3 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EPX73666.1 - 0.0003 21.5 0.0 0.00057 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EPX73666.1 - 0.00037 20.0 0.2 0.00057 19.4 0.1 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EPX73666.1 - 0.0021 18.0 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPX73666.1 - 0.0022 18.1 0.0 0.01 16.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPX73666.1 - 0.0039 16.9 0.0 0.015 15.0 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPX73666.1 - 0.0063 16.1 0.2 0.014 15.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EPX73666.1 - 0.0068 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase Torsin PF06309.6 EPX73666.1 - 0.0069 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Torsin 6PF2K PF01591.13 EPX73666.1 - 0.0072 15.4 0.2 0.026 13.5 0.0 2.0 3 0 0 3 3 3 1 6-phosphofructo-2-kinase SRPRB PF09439.5 EPX73666.1 - 0.015 14.5 0.4 0.48 9.6 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 EPX73666.1 - 0.022 15.0 0.1 0.068 13.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EPX73666.1 - 0.027 13.8 0.1 0.062 12.6 0.1 1.5 1 0 0 1 1 1 0 Thymidylate kinase ATP_bind_1 PF03029.12 EPX73666.1 - 0.046 13.2 1.6 0.071 12.6 0.1 2.1 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein VirE PF05272.6 EPX73666.1 - 0.071 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Virulence-associated protein E LBP_BPI_CETP_C PF02886.12 EPX73666.1 - 0.072 12.3 0.1 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain AAA PF00004.24 EPX73666.1 - 0.098 12.8 0.5 0.68 10.1 0.4 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MazG PF03819.12 EPX73666.1 - 0.13 12.2 0.9 0.42 10.5 0.1 2.1 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain ResIII PF04851.10 EPX73666.1 - 0.45 10.3 2.5 7.6 6.3 1.4 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EPX73667.1 - 9.2e-22 77.2 3.0 9.2e-22 77.2 2.1 2.8 2 2 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF4200 PF13863.1 EPX73667.1 - 0.003 17.5 14.7 0.003 17.5 10.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.4 EPX73667.1 - 0.01 15.6 9.7 0.01 15.6 6.7 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0118 PF01594.11 EPX73667.1 - 0.21 10.5 0.5 0.47 9.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF20 Rootletin PF15035.1 EPX73667.1 - 0.22 11.5 19.8 0.94 9.4 13.7 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Tropomyosin PF00261.15 EPX73667.1 - 0.52 9.3 28.9 1.6 7.7 1.8 2.4 1 1 1 2 2 2 0 Tropomyosin DUF2458 PF10454.4 EPX73667.1 - 0.99 9.2 21.9 0.63 9.9 3.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) ADIP PF11559.3 EPX73667.1 - 3.4 7.5 23.8 0.56 10.1 5.2 3.1 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EPX73667.1 - 5.1 6.6 21.3 0.52 9.8 0.8 3.9 3 1 1 4 4 4 0 Septum formation initiator USP7_ICP0_bdg PF12436.3 EPX73668.1 - 4.8e-62 209.4 0.3 5.2e-61 206.0 0.0 2.5 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 EPX73668.1 - 4.8e-56 189.8 2.5 7e-56 189.2 1.7 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EPX73668.1 - 1.1e-51 175.3 1.8 5.9e-49 166.3 0.5 2.5 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 EPX73668.1 - 2.9e-30 105.7 0.3 4.6e-30 105.0 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SKIP_SNW PF02731.10 EPX73669.1 - 3.4e-66 221.5 2.9 3.4e-66 221.5 2.0 2.1 2 0 0 2 2 2 1 SKIP/SNW domain Cwf_Cwc_15 PF04889.7 EPX73669.1 - 0.13 11.9 13.8 0.28 10.8 9.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Septin PF00735.13 EPX73670.1 - 4.7e-98 327.6 1.0 4.7e-98 327.6 0.7 1.7 1 1 1 2 2 2 1 Septin AAA_33 PF13671.1 EPX73670.1 - 5.7e-05 23.0 0.1 0.0012 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPX73670.1 - 7e-05 22.9 0.0 0.00021 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPX73670.1 - 8.6e-05 22.8 0.0 8.6e-05 22.8 0.0 2.7 2 1 0 2 2 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EPX73670.1 - 0.00027 20.4 0.6 0.0044 16.5 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 EPX73670.1 - 0.00043 20.0 0.1 0.0011 18.7 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EPX73670.1 - 0.00055 18.9 0.9 0.0021 17.0 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein Pox_A32 PF04665.7 EPX73670.1 - 0.00074 18.8 1.1 0.0015 17.8 0.0 2.1 2 0 0 2 2 2 1 Poxvirus A32 protein RNA_helicase PF00910.17 EPX73670.1 - 0.0011 19.1 0.0 0.0031 17.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.18 EPX73670.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase KAP_NTPase PF07693.9 EPX73670.1 - 0.0014 17.7 0.2 0.0031 16.5 0.2 1.5 1 1 0 1 1 1 1 KAP family P-loop domain DUF258 PF03193.11 EPX73670.1 - 0.0014 17.8 0.0 0.0034 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EPX73670.1 - 0.002 17.6 1.7 0.14 11.5 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EPX73670.1 - 0.0047 17.7 5.3 0.011 16.5 0.1 2.6 2 2 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPX73670.1 - 0.0064 16.7 0.3 0.046 14.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA PF00004.24 EPX73670.1 - 0.0094 16.1 0.1 0.059 13.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EPX73670.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EPX73670.1 - 0.022 14.7 0.1 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PRK PF00485.13 EPX73670.1 - 0.023 14.2 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.4 EPX73670.1 - 0.026 14.0 0.8 0.12 11.8 0.1 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 EPX73670.1 - 0.031 13.6 0.0 0.071 12.5 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.21 EPX73670.1 - 0.033 13.6 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 EPX73670.1 - 0.04 13.5 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EPX73670.1 - 0.041 13.4 0.4 0.097 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EPX73670.1 - 0.044 14.2 0.1 0.13 12.7 0.1 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_14 PF13173.1 EPX73670.1 - 0.052 13.4 0.1 0.052 13.4 0.1 2.0 2 1 0 2 2 2 0 AAA domain IncA PF04156.9 EPX73670.1 - 0.26 10.8 6.8 0.47 10.0 4.7 1.4 1 0 0 1 1 1 0 IncA protein Dynamin_N PF00350.18 EPX73670.1 - 2.6 7.8 6.2 2 8.2 0.3 2.9 2 1 1 3 3 3 0 Dynamin family Ribonuclease_3 PF00636.21 EPX73671.1 - 1.3e-45 154.4 2.1 1e-23 83.9 0.0 4.1 4 0 0 4 4 4 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EPX73671.1 - 6.7e-27 93.9 2.5 5.4e-12 45.7 0.2 4.0 4 1 0 4 4 4 3 Ribonuclease-III-like Dicer_dimer PF03368.9 EPX73671.1 - 6.5e-23 80.3 0.0 1.5e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 EPX73671.1 - 3.7e-16 58.7 0.2 2.1e-15 56.3 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX73671.1 - 2.5e-12 46.9 1.7 8.6e-12 45.2 0.2 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPX73671.1 - 7.5e-10 38.5 0.1 2e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 EPX73671.1 - 0.0066 16.9 0.1 0.05 14.1 0.0 2.4 2 0 0 2 2 2 1 Double-stranded RNA binding motif Svf1 PF08622.5 EPX73672.1 - 1.5e-111 372.5 0.1 1.9e-111 372.1 0.1 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EPX73672.1 - 5.6e-05 22.6 0.0 6.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) AA_permease_2 PF13520.1 EPX73673.1 - 7.4e-65 219.1 41.9 7.4e-65 219.1 29.0 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPX73673.1 - 1e-19 70.2 38.3 1.4e-19 69.8 26.5 1.1 1 0 0 1 1 1 1 Amino acid permease Kei1 PF08552.6 EPX73673.1 - 0.17 11.5 8.9 0.27 10.8 0.1 3.3 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 CbtB PF09489.5 EPX73673.1 - 0.78 9.6 3.8 0.76 9.7 0.5 2.6 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Atx10homo_assoc PF09759.4 EPX73674.1 - 3.3e-31 107.0 0.0 6.6e-31 106.0 0.0 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Arrestin_N PF00339.24 EPX73675.1 - 7.5e-26 90.7 0.0 1.2e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EPX73675.1 - 2.8e-20 72.8 0.0 7.2e-18 65.0 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EPX73675.1 - 0.0094 15.4 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Pox_F16 PF04708.7 EPX73676.1 - 0.046 13.0 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus F16 protein FAD_binding_1 PF00667.15 EPX73677.1 - 2.6e-67 226.4 0.0 4.9e-67 225.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EPX73677.1 - 1.1e-09 38.7 0.0 3.4e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EPX73677.1 - 0.037 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Ran-binding PF05508.6 EPX73678.1 - 2.1e-85 286.2 1.0 3.1e-85 285.7 0.7 1.2 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.22 EPX73679.1 - 6.5e-47 159.4 0.0 1e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPX73679.1 - 8.5e-27 93.2 0.6 2e-26 92.0 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPX73679.1 - 2.1e-07 30.9 0.2 5.7e-07 29.5 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPX73679.1 - 8.2e-05 22.5 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EPX73679.1 - 0.0045 15.7 0.3 0.0088 14.7 0.2 1.4 1 0 0 1 1 1 1 G-protein alpha subunit Sec1 PF00995.18 EPX73680.1 - 6.5e-119 398.1 0.1 7.9e-119 397.8 0.1 1.1 1 0 0 1 1 1 1 Sec1 family RPA_C PF08784.6 EPX73681.1 - 6.6e-17 61.8 0.1 1.5e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EPX73681.1 - 1e-07 31.6 0.2 1.7e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Git3 PF11710.3 EPX73682.1 - 7e-44 149.8 15.9 7e-44 149.8 11.0 1.8 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EPX73682.1 - 1.8e-08 34.0 0.6 6.4e-08 32.2 0.1 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Meiotic_rec114 PF03525.9 EPX73683.1 - 4.5e-63 212.7 0.0 7.7e-63 211.9 0.0 1.4 1 1 0 1 1 1 1 Meiotic recombination protein rec114 Inositol_P PF00459.20 EPX73684.1 - 3.1e-53 180.8 0.1 4.4e-52 177.0 0.1 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family zf-C3HC PF07967.8 EPX73685.1 - 1.1e-24 86.7 11.0 6.1e-22 77.8 1.3 3.1 1 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EPX73685.1 - 9.2e-18 63.8 8.1 4.4e-16 58.4 0.4 3.0 3 0 0 3 3 3 2 Rsm1-like BIR PF00653.16 EPX73685.1 - 0.00071 19.9 4.8 0.33 11.3 0.2 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C2HC_2 PF13913.1 EPX73685.1 - 0.059 13.0 0.9 3.5 7.3 0.0 2.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TCO89 PF10452.4 EPX73686.1 - 1.2e-21 77.3 16.0 1.4e-11 44.0 1.5 2.1 1 1 0 2 2 2 2 TORC1 subunit TCO89 Pkinase PF00069.20 EPX73687.1 - 3.6e-55 186.9 0.0 4.5e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73687.1 - 3.4e-31 108.2 0.0 4.4e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX73687.1 - 4.9e-07 29.0 0.0 0.00028 19.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.6 EPX73687.1 - 0.0036 16.1 0.0 0.0057 15.5 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 EPX73687.1 - 0.0048 16.0 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX73687.1 - 0.005 16.6 0.1 0.012 15.3 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family PRK PF00485.13 EPX73688.1 - 7.9e-63 211.5 0.0 1.1e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EPX73688.1 - 2.4e-28 98.7 0.1 3.7e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EPX73688.1 - 1e-11 45.7 0.0 2.3e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPX73688.1 - 3.9e-08 33.6 0.0 1.1e-07 32.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPX73688.1 - 4.4e-05 23.3 0.0 0.00048 20.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPX73688.1 - 7.3e-05 21.9 0.0 0.00025 20.2 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.24 EPX73688.1 - 0.0078 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPX73688.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EPX73688.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter CPT PF07931.7 EPX73688.1 - 0.028 14.0 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.1 EPX73688.1 - 0.043 13.4 0.2 1.3 8.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.9 EPX73688.1 - 0.046 13.4 0.0 0.14 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EPX73688.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 SKI PF01202.17 EPX73688.1 - 0.052 13.4 0.0 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase MobB PF03205.9 EPX73688.1 - 0.063 12.9 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EPX73688.1 - 0.069 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EPX73688.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain HMG-CoA_red PF00368.13 EPX73689.1 - 6.3e-155 515.4 1.0 8.4e-155 515.0 0.7 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EPX73689.1 - 0.006 16.2 0.4 0.014 15.0 0.3 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif TPR_MLP1_2 PF07926.7 EPX73690.1 - 3.1e-22 78.7 20.2 3.1e-22 78.7 14.0 17.5 3 2 12 16 16 16 6 TPR/MLP1/MLP2-like protein Filament PF00038.16 EPX73690.1 - 0.00068 19.1 38.1 0.00068 19.1 26.4 10.8 2 2 4 8 8 8 2 Intermediate filament protein ENTH PF01417.15 EPX73691.1 - 1.2e-46 157.6 0.0 1.7e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.6 EPX73691.1 - 1.6e-26 92.1 126.8 1e+04 -3.4 59.9 6.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1720) ANTH PF07651.11 EPX73691.1 - 0.00016 20.4 0.0 0.00029 19.6 0.0 1.4 1 0 0 1 1 1 1 ANTH domain Methyltransf_23 PF13489.1 EPX73692.1 - 3.9e-28 98.1 0.0 6.3e-28 97.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX73692.1 - 2.8e-24 85.4 0.0 4.5e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX73692.1 - 1.6e-21 76.5 0.0 2.9e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX73692.1 - 5.4e-20 72.0 0.0 1e-19 71.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX73692.1 - 4.9e-17 62.2 0.0 1.7e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EPX73692.1 - 6.6e-13 48.3 0.0 9.4e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EPX73692.1 - 1.8e-11 43.6 0.0 2.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EPX73692.1 - 1.5e-10 41.3 0.0 2.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EPX73692.1 - 2.6e-10 39.5 0.0 3.9e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.6 EPX73692.1 - 1.3e-08 34.5 0.0 1.8e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 EPX73692.1 - 1.6e-08 34.1 0.0 2.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EPX73692.1 - 8.6e-08 31.5 0.0 1.2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EPX73692.1 - 1.1e-07 31.9 0.0 3e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EPX73692.1 - 3.1e-06 26.2 0.0 4.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.1 EPX73692.1 - 4.7e-06 26.3 0.0 8.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EPX73692.1 - 0.00039 19.9 0.0 0.0008 18.9 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.15 EPX73692.1 - 0.00062 18.8 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GidB PF02527.10 EPX73692.1 - 0.0017 17.5 0.0 0.0036 16.4 0.0 1.5 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_15 PF09445.5 EPX73692.1 - 0.0036 16.8 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TehB PF03848.9 EPX73692.1 - 0.0036 16.4 0.0 0.005 16.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 EPX73692.1 - 0.012 14.9 0.1 0.031 13.6 0.1 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW CheR PF01739.13 EPX73692.1 - 0.014 14.7 1.6 0.19 11.0 0.0 2.5 2 1 1 3 3 2 0 CheR methyltransferase, SAM binding domain PCMT PF01135.14 EPX73692.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.8 EPX73692.1 - 0.075 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Snf7 PF03357.16 EPX73693.1 - 8.2e-49 165.2 20.0 9.8e-49 165.0 13.8 1.1 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.15 EPX73693.1 - 0.0086 15.8 21.1 0.039 13.7 0.0 3.6 2 1 1 3 3 3 1 Prefoldin subunit NuA4 PF09340.5 EPX73693.1 - 0.086 12.4 5.3 0.058 13.0 2.1 1.9 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Spatacsin_C PF14649.1 EPX73693.1 - 0.1 11.4 6.6 0.13 11.1 4.6 1.1 1 0 0 1 1 1 0 Spatacsin C-terminus Sin3_corepress PF08295.7 EPX73693.1 - 0.16 11.7 2.5 0.32 10.7 1.3 1.8 1 1 0 1 1 1 0 Sin3 family co-repressor Seryl_tRNA_N PF02403.17 EPX73693.1 - 0.27 11.2 16.7 0.11 12.5 2.3 2.8 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF4238 PF14022.1 EPX73693.1 - 0.31 10.2 4.8 0.43 9.8 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) GAS PF13851.1 EPX73693.1 - 0.57 9.3 18.2 1.5 8.0 9.7 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding OmpH PF03938.9 EPX73693.1 - 0.59 10.0 27.6 13 5.6 12.5 2.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF1569 PF07606.6 EPX73693.1 - 0.67 9.8 4.4 3.9 7.3 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1569) NPV_P10 PF05531.7 EPX73693.1 - 0.75 10.0 12.8 2.6 8.3 2.7 3.7 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein Ycf15 PF10705.4 EPX73693.1 - 0.85 9.7 3.4 0.6 10.1 1.0 1.8 2 0 0 2 2 1 0 Chloroplast protein precursor Ycf15 putative Nup54 PF13874.1 EPX73693.1 - 0.95 9.1 15.8 0.22 11.2 3.9 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF342 PF03961.8 EPX73693.1 - 1.2 7.4 13.9 0.09 11.1 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Cytochrom_C PF00034.16 EPX73693.1 - 1.6 9.5 5.1 27 5.6 3.2 2.6 1 1 0 1 1 1 0 Cytochrome c Osmo_CC PF08946.5 EPX73693.1 - 2.6 8.1 0.0 2.6 8.1 0.0 3.6 3 1 1 4 4 4 0 Osmosensory transporter coiled coil NEP PF10167.4 EPX73693.1 - 2.6 7.7 10.3 0.75 9.5 4.9 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein DUF883 PF05957.8 EPX73693.1 - 3 8.2 5.4 1.2 9.5 0.2 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4200 PF13863.1 EPX73693.1 - 4.9 7.1 21.4 0.31 10.9 3.7 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF4140 PF13600.1 EPX73693.1 - 8 6.9 12.6 4.5 7.7 0.1 3.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Allexi_40kDa PF05549.6 EPX73693.1 - 8.2 5.6 9.6 3 7.0 0.3 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein SAPS PF04499.10 EPX73694.1 - 2.9e-164 547.2 0.0 2.9e-164 547.2 0.0 3.0 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Dus PF01207.12 EPX73695.1 - 5.2e-66 222.5 0.0 6.4e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 EPX73695.1 - 0.00053 19.0 0.0 0.001 18.1 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PEP_mutase PF13714.1 EPX73695.1 - 0.023 13.9 0.1 0.12 11.6 0.1 1.8 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase TMP-TENI PF02581.12 EPX73695.1 - 0.038 13.1 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI SelB-wing_1 PF09105.5 EPX73695.1 - 0.043 13.4 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Pkinase PF00069.20 EPX73696.1 - 3.9e-53 180.2 0.2 5.8e-53 179.6 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73696.1 - 6.9e-23 81.0 0.1 4.5e-22 78.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EPX73696.1 - 0.0027 17.1 1.2 0.026 13.8 0.8 2.3 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 EPX73696.1 - 0.062 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Vps35 PF03635.12 EPX73697.1 - 1e-236 787.8 20.9 1.2e-236 787.5 14.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Thioredoxin PF00085.15 EPX73698.1 - 7.3e-06 25.6 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Glu-tRNAGln PF02686.10 EPX73699.1 - 0.037 13.8 0.2 0.07 12.9 0.1 1.5 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit CarD_CdnL_TRCF PF02559.11 EPX73699.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 CarD-like/TRCF domain UQ_con PF00179.21 EPX73700.1 - 2.7e-37 127.3 0.0 3.2e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EPX73700.1 - 0.042 13.5 0.2 0.082 12.6 0.2 1.5 1 1 0 1 1 1 0 UEV domain Aminotran_3 PF00202.16 EPX73701.1 - 9.2e-98 327.2 0.0 1.1e-97 326.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.12 EPX73701.1 - 0.0038 16.3 0.0 0.0062 15.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EPX73701.1 - 0.054 12.2 0.0 0.1 11.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V HbrB PF08539.6 EPX73702.1 - 5.2e-39 133.6 0.8 8.5e-39 132.9 0.5 1.3 1 0 0 1 1 1 1 HbrB-like Glyco_transf_15 PF01793.11 EPX73703.1 - 5.7e-127 423.2 14.7 7.2e-127 422.8 10.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Lactamase_B_2 PF12706.2 EPX73704.1 - 2.6e-14 53.2 0.0 3.2e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPX73704.1 - 1.2e-11 44.6 0.1 2.1e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EPX73704.1 - 0.033 13.8 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Gp37 PF09646.5 EPX73704.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Gp37 protein Gtr1_RagA PF04670.7 EPX73705.1 - 5e-70 235.2 0.7 6.6e-70 234.8 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EPX73705.1 - 3.1e-05 23.2 0.0 4.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EPX73705.1 - 0.0011 19.4 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EPX73705.1 - 0.0046 16.1 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPX73705.1 - 0.02 14.8 0.0 0.077 12.9 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EPX73705.1 - 0.07 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ADH_N PF08240.7 EPX73706.1 - 9.6e-35 118.6 1.3 1.8e-34 117.7 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPX73706.1 - 1.7e-27 95.5 1.1 2.8e-27 94.8 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPX73706.1 - 0.022 15.6 0.0 0.052 14.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1777 PF08648.7 EPX73707.1 - 1.6e-23 83.3 36.4 1.6e-23 83.3 25.3 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF1777) AMP-binding PF00501.23 EPX73708.1 - 1.4e-36 125.8 0.0 1.8e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPX73708.1 - 1.3e-35 122.5 0.0 2.2e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EPX73708.1 - 1.7e-08 34.2 0.0 3.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EPX73708.1 - 4.8e-05 23.5 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EPX73708.1 - 0.013 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Lantibiotic_a PF14867.1 EPX73708.1 - 0.023 13.9 0.1 0.081 12.1 0.0 2.0 1 0 0 1 1 1 0 Lantibiotic alpha NAD_binding_10 PF13460.1 EPX73708.1 - 0.033 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EPX73708.1 - 0.036 12.7 0.0 0.07 11.8 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EPX73708.1 - 0.038 13.2 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 EPX73708.1 - 0.043 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Ribosomal_L39 PF00832.15 EPX73709.1 - 9.3e-23 79.4 10.5 1.1e-22 79.2 7.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Ribosomal_L13e PF01294.13 EPX73709.1 - 0.05 13.0 1.8 0.054 12.9 1.3 1.0 1 0 0 1 1 1 0 Ribosomal protein L13e DUF2205 PF10224.4 EPX73710.1 - 1.9e-07 30.5 1.2 2.2e-07 30.3 0.8 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) ATP-synt_D PF01813.12 EPX73710.1 - 0.011 15.3 0.3 0.012 15.2 0.2 1.0 1 0 0 1 1 1 0 ATP synthase subunit D His_kinase PF06580.8 EPX73710.1 - 0.024 14.5 0.5 0.026 14.4 0.3 1.1 1 0 0 1 1 1 0 Histidine kinase Ead_Ea22 PF13935.1 EPX73710.1 - 0.028 14.7 0.1 0.029 14.7 0.1 1.1 1 0 0 1 1 1 0 Ead/Ea22-like protein Tropomyosin PF00261.15 EPX73710.1 - 0.036 13.1 1.5 0.043 12.9 1.0 1.0 1 0 0 1 1 1 0 Tropomyosin bZIP_2 PF07716.10 EPX73710.1 - 0.2 11.5 5.5 0.31 10.8 3.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper ASF1_hist_chap PF04729.8 EPX73711.1 - 7.3e-63 210.8 0.6 9.9e-63 210.3 0.4 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone CENP-T PF15511.1 EPX73711.1 - 0.46 9.6 19.8 0.53 9.4 13.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EPX73711.1 - 0.82 7.5 26.3 0.88 7.4 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 EPX73711.1 - 1 8.4 21.0 1.4 8.0 14.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EPX73711.1 - 2.4 6.5 28.2 2.7 6.3 19.5 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EPX73711.1 - 10 4.0 16.5 12 3.8 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Clat_adaptor_s PF01217.15 EPX73712.1 - 1.8e-08 34.2 0.1 3.6e-08 33.2 0.0 1.5 1 1 1 2 2 2 1 Clathrin adaptor complex small chain PDEase_II PF02112.10 EPX73713.1 - 3e-94 315.6 0.1 3.6e-94 315.4 0.1 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EPX73713.1 - 3.2e-06 26.8 0.1 4.7e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SPRY PF00622.23 EPX73714.1 - 2.1e-17 63.3 0.4 1.1e-16 61.0 0.1 2.0 2 0 0 2 2 2 1 SPRY domain UBX PF00789.15 EPX73715.1 - 3.8e-18 65.3 0.0 8.1e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EPX73715.1 - 4.6e-05 22.8 0.7 9.7e-05 21.8 0.5 1.5 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EPX73715.1 - 0.0078 16.0 0.0 0.024 14.4 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DDRGK PF09756.4 EPX73715.1 - 1 8.7 14.0 2 7.7 9.7 1.4 1 0 0 1 1 1 0 DDRGK domain YqfQ PF14181.1 EPX73715.1 - 1.5 8.8 6.0 2.7 7.9 4.1 1.4 1 0 0 1 1 1 0 YqfQ-like protein DUF1682 PF07946.9 EPX73715.1 - 4 6.1 10.4 6.7 5.4 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LSM PF01423.17 EPX73716.1 - 9.9e-18 63.4 0.1 1.2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain TRAPPC10 PF12584.3 EPX73718.1 - 1.5e-05 24.5 0.0 3.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_12 PF13424.1 EPX73718.1 - 0.0054 16.6 0.5 0.035 14.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EPX73718.1 - 0.0062 16.0 0.4 0.016 14.7 0.2 1.7 1 1 0 1 1 1 1 Foie gras liver health family 1 Ribosomal_S28e PF01200.13 EPX73719.1 - 3.4e-34 116.4 2.0 3.6e-34 116.3 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MutS_V PF00488.16 EPX73720.1 - 6.3e-89 297.4 0.0 9.5e-89 296.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPX73720.1 - 4.3e-46 157.2 0.0 8.9e-46 156.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EPX73720.1 - 1.9e-33 114.8 0.3 5.6e-33 113.3 0.2 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EPX73720.1 - 1.6e-21 76.7 0.0 5.3e-21 75.1 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EPX73720.1 - 7.3e-18 64.5 1.9 3.9e-17 62.2 1.1 2.4 2 0 0 2 2 2 1 MutS family domain IV ABC_tran PF00005.22 EPX73720.1 - 0.021 15.1 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EPX73720.1 - 0.032 14.1 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPX73720.1 - 0.036 13.6 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EPX73720.1 - 0.17 12.2 0.0 0.17 12.2 0.0 3.8 3 1 0 3 3 3 0 AAA domain SWIB PF02201.13 EPX73721.1 - 1.1e-26 92.3 2.0 1.2e-26 92.2 0.5 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 EPX73721.1 - 3.7e-10 39.4 0.7 6.4e-10 38.6 0.5 1.4 1 0 0 1 1 1 1 DEK C terminal domain DUF960 PF06124.6 EPX73721.1 - 0.11 12.7 0.1 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Staphylococcal protein of unknown function (DUF960) zf-C3HC4_3 PF13920.1 EPX73722.1 - 2.3e-07 30.3 10.4 2.3e-07 30.3 7.2 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Yae1_N PF09811.4 EPX73723.1 - 1.6e-08 33.9 6.1 3.3e-08 32.9 4.2 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Cytochrom_C PF00034.16 EPX73724.1 - 2.7e-10 40.9 0.1 4.1e-10 40.3 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EPX73724.1 - 1.5e-07 31.4 3.6 1.5e-06 28.2 2.5 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EPX73724.1 - 0.0048 16.3 1.3 0.046 13.1 0.1 2.2 2 1 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 EPX73724.1 - 0.021 15.1 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Nuc_deoxyrib_tr PF05014.10 EPX73725.1 - 5.9e-29 100.2 0.0 7.4e-29 99.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase AMP-binding PF00501.23 EPX73726.1 - 3.8e-90 302.2 0.0 4.5e-90 302.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPX73726.1 - 9.3e-18 64.9 0.0 2e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain B12D PF06522.6 EPX73728.1 - 1.1e-07 31.4 0.1 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit LSM PF01423.17 EPX73729.1 - 2.7e-18 65.2 0.8 3.4e-18 64.9 0.6 1.1 1 0 0 1 1 1 1 LSM domain DUF2986 PF11661.3 EPX73729.1 - 0.39 11.0 0.3 0.39 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Aminotran_1_2 PF00155.16 EPX73730.1 - 2e-57 194.8 0.0 2.7e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPX73730.1 - 7.9e-05 21.5 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 EPX73730.1 - 0.00064 18.3 0.0 0.0014 17.2 0.0 1.5 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 EPX73730.1 - 0.0033 16.6 0.0 0.0046 16.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EPX73730.1 - 0.24 10.4 0.0 0.44 9.5 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family GCV_T PF01571.16 EPX73731.1 - 1.9e-15 56.8 0.0 3.7e-11 42.7 0.0 2.2 1 1 1 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EPX73731.1 - 0.0084 16.1 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain IF-2B PF01008.12 EPX73732.1 - 8e-90 300.6 0.1 1e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pro_isomerase PF00160.16 EPX73733.1 - 1.5e-44 151.9 0.0 2.5e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Acetyltransf_1 PF00583.19 EPX73734.1 - 1.3e-06 28.3 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EPX73734.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EPX73734.1 - 0.0015 18.7 0.0 0.0021 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPX73734.1 - 0.011 15.8 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPX73734.1 - 0.036 14.2 0.0 0.061 13.4 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPX73734.1 - 0.04 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Epimerase PF01370.16 EPX73735.1 - 2e-20 73.2 0.1 1e-19 70.9 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPX73735.1 - 1.1e-17 63.6 0.0 2.1e-17 62.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPX73735.1 - 2.1e-10 40.9 0.0 4.3e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPX73735.1 - 5.2e-10 38.6 0.0 3e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EPX73735.1 - 2.8e-07 29.7 0.2 3e-06 26.3 0.1 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPX73735.1 - 3e-06 27.2 0.9 2.8e-05 24.1 0.1 2.5 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EPX73735.1 - 0.0023 17.2 0.1 0.0038 16.5 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EPX73735.1 - 0.32 10.6 1.6 2.2 7.8 0.3 2.3 2 1 0 2 2 2 0 KR domain bZIP_1 PF00170.16 EPX73736.1 - 2.4e-08 33.8 12.8 3.4e-08 33.3 8.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPX73736.1 - 3.6e-08 33.1 12.0 5.7e-08 32.4 8.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EPX73736.1 - 0.015 15.5 11.1 0.024 14.9 7.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2514 PF10721.4 EPX73736.1 - 0.1 12.2 5.0 0.12 12.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) GCN5L1 PF06320.8 EPX73736.1 - 0.52 10.1 6.8 1.1 9.0 4.7 1.6 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Fib_alpha PF08702.5 EPX73736.1 - 0.78 9.8 4.6 1.1 9.3 3.0 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family WXG100 PF06013.7 EPX73736.1 - 0.86 9.6 7.5 0.42 10.6 1.7 2.3 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF16 PF01519.11 EPX73736.1 - 1.1 9.5 4.7 1.7 8.9 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Ribosomal_L2_C PF03947.13 EPX73737.1 - 1.1e-37 128.7 3.9 1.2e-37 128.6 2.1 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPX73737.1 - 2.5e-15 56.1 0.0 5.4e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Aldo_ket_red PF00248.16 EPX73738.1 - 1.4e-72 243.9 0.0 1.6e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 EPX73739.1 - 8.9e-30 103.4 3.4 2.3e-29 102.0 2.4 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Asp_Glu_race PF01177.17 EPX73740.1 - 3.6e-28 98.9 0.1 4.1e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Allantoicase PF03561.10 EPX73741.1 - 9.6e-101 333.5 0.0 3.4e-53 179.1 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat GWT1 PF06423.7 EPX73742.1 - 0.027 14.5 0.8 0.035 14.1 0.5 1.2 1 0 0 1 1 1 0 GWT1 WTF PF03303.8 EPX73742.1 - 4 6.7 11.6 39 3.5 6.6 2.6 1 1 1 2 2 2 0 WTF protein FTR1 PF03239.9 EPX73743.1 - 1.3e-93 313.2 9.5 1.7e-93 312.9 6.6 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family Cytochrom_C_asm PF01578.15 EPX73743.1 - 0.00074 19.1 5.0 0.0064 16.0 1.4 2.5 2 0 0 2 2 2 1 Cytochrome C assembly protein DUF3301 PF11743.3 EPX73743.1 - 0.072 12.6 0.1 0.21 11.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Cucumo_2B PF03263.8 EPX73743.1 - 0.082 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Cucumovirus protein 2B YajC PF02699.10 EPX73743.1 - 0.082 12.5 0.5 3.8 7.2 0.1 2.9 2 0 0 2 2 2 0 Preprotein translocase subunit PIG-F PF06699.6 EPX73743.1 - 1.5 8.7 8.6 1.4 8.8 0.2 3.1 4 0 0 4 4 4 0 GPI biosynthesis protein family Pig-F COX14 PF14880.1 EPX73743.1 - 1.7 8.3 5.2 1 9.0 0.1 2.9 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Cu-oxidase PF00394.17 EPX73744.1 - 1e-45 155.4 5.7 4.1e-40 137.2 0.4 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPX73744.1 - 2.5e-41 140.4 8.5 7.7e-39 132.3 0.9 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EPX73744.1 - 4.8e-37 126.3 7.5 2.4e-35 120.8 1.0 3.6 4 0 0 4 4 4 2 Multicopper oxidase DJ-1_PfpI PF01965.19 EPX73745.1 - 1.4e-10 40.7 0.0 1.9e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family PS_pyruv_trans PF04230.8 EPX73745.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Ribonuc_red_lgC PF02867.10 EPX73746.1 - 2.1e-214 713.0 0.0 2.9e-214 712.6 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EPX73746.1 - 3.5e-23 81.1 0.0 9.8e-23 79.7 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EPX73746.1 - 2.9e-15 56.4 0.0 1.1e-14 54.5 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain Ras PF00071.17 EPX73747.1 - 4.2e-56 188.8 0.0 5e-56 188.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX73747.1 - 8.1e-15 55.3 0.0 1.3e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX73747.1 - 9e-07 28.2 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPX73747.1 - 0.0032 16.6 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPX73747.1 - 0.046 12.8 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF4536 PF15055.1 EPX73748.1 - 1.5e-05 24.9 0.6 1.5e-05 24.9 0.4 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4536) TRP PF06011.7 EPX73749.1 - 1.9e-94 316.7 35.5 1.9e-94 316.7 24.6 1.4 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPX73749.1 - 8.1e-38 129.6 0.8 1.2e-37 129.0 0.6 1.3 1 0 0 1 1 1 1 ML-like domain DEAD PF00270.24 EPX73750.1 - 4.1e-45 153.3 0.0 1.2e-44 151.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EPX73750.1 - 1.1e-21 76.1 0.6 2e-21 75.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EPX73750.1 - 5.8e-21 74.1 0.0 2e-20 72.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VIT1 PF01988.14 EPX73750.1 - 0.73 9.2 6.6 18 4.7 4.6 2.2 1 1 0 1 1 1 0 VIT family Vfa1 PF08432.5 EPX73750.1 - 3.1 7.7 16.8 6.3 6.7 11.7 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SH2_2 PF14633.1 EPX73751.1 - 4.3e-100 333.3 0.6 2.4e-99 330.8 0.1 2.4 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 EPX73751.1 - 7.1e-49 164.6 6.9 7.1e-49 164.6 4.8 3.1 2 1 1 3 3 3 1 Death-like domain of SPT6 YqgF PF14639.1 EPX73751.1 - 5.2e-48 162.4 0.1 3.9e-47 159.5 0.0 2.4 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 EPX73751.1 - 1.1e-45 153.9 0.0 3.2e-45 152.4 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HTH_44 PF14641.1 EPX73751.1 - 1.6e-38 131.3 2.2 1.6e-38 131.3 1.5 2.2 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 EPX73751.1 - 2.3e-18 66.1 20.6 2.3e-18 66.1 14.3 4.6 3 2 2 5 5 5 1 Acidic N-terminal SPT6 SH2 PF00017.19 EPX73751.1 - 4.4e-05 23.2 0.0 0.00015 21.4 0.0 2.0 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 EPX73751.1 - 0.00042 20.3 0.1 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 S1 RNA binding domain HHH_3 PF12836.2 EPX73751.1 - 0.028 14.3 0.0 0.079 12.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif MRC1 PF09444.5 EPX73752.1 - 1.4e-31 109.7 18.1 1.4e-31 109.7 12.5 6.7 4 2 3 7 7 7 1 MRC1-like domain Ribosomal_S25 PF03297.10 EPX73753.1 - 2.9e-34 117.2 0.7 3.2e-34 117.1 0.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein UPF0160 PF03690.8 EPX73754.1 - 1.6e-120 402.3 0.0 1.8e-120 402.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Rsbr_N PF08678.5 EPX73754.1 - 0.19 11.6 0.7 0.53 10.1 0.1 1.9 2 0 0 2 2 2 0 Rsbr N terminal CTP_transf_2 PF01467.21 EPX73755.1 - 5.5e-07 29.7 0.0 8.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase ATP-sulfurylase PF01747.12 EPX73755.1 - 0.072 12.3 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 ATP-sulfurylase DEAD PF00270.24 EPX73756.1 - 4.1e-18 65.4 0.0 7.8e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EPX73756.1 - 3.8e-08 33.3 5.6 2.8e-07 30.5 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPX73756.1 - 1.3e-07 31.3 0.2 3e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 EPX73756.1 - 0.0012 18.1 0.0 0.034 13.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein zf-CCHC PF00098.18 EPX73757.1 - 2.5e-09 36.6 31.0 0.001 18.9 1.2 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EPX73757.1 - 2.6e-06 27.0 28.9 0.025 14.2 0.5 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 EPX73757.1 - 0.036 13.5 25.1 0.52 9.8 0.3 4.5 2 1 2 4 4 4 0 Zinc knuckle HMG14_17 PF01101.13 EPX73757.1 - 0.99 10.1 7.1 3 8.6 0.3 2.3 2 0 0 2 2 2 0 HMG14 and HMG17 zf-C2H2 PF00096.21 EPX73758.1 - 1.7e-08 34.2 11.5 0.00014 22.0 0.2 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPX73758.1 - 2.6e-07 30.5 11.5 5.2e-06 26.4 0.1 4.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPX73758.1 - 0.001 19.2 9.0 0.017 15.4 0.1 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger DUF1090 PF06476.7 EPX73758.1 - 0.053 13.1 0.2 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) DUF1687 PF07955.6 EPX73759.1 - 1.2e-17 64.1 0.4 1.9e-17 63.5 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) DUF2353 PF09789.4 EPX73759.1 - 0.062 12.5 0.0 0.096 11.9 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Mt_ATP-synt_B PF05405.9 EPX73759.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Peptidase_A22B PF04258.8 EPX73760.1 - 3.7e-70 236.7 6.8 1.1e-64 218.7 4.9 2.0 1 1 1 2 2 2 2 Signal peptide peptidase DUF1119 PF06550.6 EPX73760.1 - 2.7e-06 26.7 12.4 6e-05 22.3 7.9 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) POP1 PF06978.6 EPX73761.1 - 6e-56 189.0 4.3 1.2e-55 188.0 3.0 1.6 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EPX73761.1 - 3e-29 100.6 0.9 3e-29 100.6 0.6 2.0 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.16 EPX73761.1 - 0.00057 19.3 0.0 0.58 9.4 0.0 2.4 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain TYW3 PF02676.9 EPX73762.1 - 5.7e-65 218.2 0.0 6.7e-65 218.0 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 CENP-O PF09496.5 EPX73763.1 - 7.5e-12 45.3 0.1 2.2e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component phiKZ_IP PF12699.2 EPX73763.1 - 0.014 14.3 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins bZIP_1 PF00170.16 EPX73763.1 - 0.16 11.9 2.1 0.29 11.0 1.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor DIOX_N PF14226.1 EPX73764.1 - 7.8e-25 87.6 0.2 1.2e-21 77.3 0.0 2.2 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPX73764.1 - 4.8e-19 68.4 0.0 1.1e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Myc_target_1 PF15179.1 EPX73764.1 - 0.022 14.3 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 Myc target protein 1 Hydrolase_3 PF08282.7 EPX73765.1 - 9.7e-46 156.3 0.0 1.1e-45 156.2 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EPX73765.1 - 1.4e-07 31.0 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EPX73765.1 - 0.0045 17.1 0.0 0.024 14.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPX73765.1 - 0.024 15.0 0.7 22 5.3 0.1 2.9 1 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 EPX73766.1 - 5e-29 100.9 6.2 8.1e-29 100.2 4.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX73766.1 - 6.5e-07 29.1 4.3 6.5e-07 29.1 3.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAZ_siRNAbind PF12212.3 EPX73766.1 - 0.071 12.7 0.1 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain Methyltransf_11 PF08241.7 EPX73767.1 - 3.6e-20 72.2 0.0 1.5e-19 70.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX73767.1 - 1.1e-14 54.2 0.0 1.9e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX73767.1 - 1.3e-12 47.7 0.0 1.9e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX73767.1 - 7.7e-12 45.4 0.0 1.7e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX73767.1 - 9.4e-11 42.0 0.0 2.1e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX73767.1 - 9.9e-10 38.9 0.0 1.8e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPX73767.1 - 1.6e-09 37.2 0.0 2.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 EPX73767.1 - 2.4e-06 26.6 0.0 3.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 EPX73767.1 - 5.6e-06 25.8 0.0 9.8e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 EPX73767.1 - 1.2e-05 25.0 0.0 4e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_29 PF03141.11 EPX73767.1 - 0.00011 20.7 0.0 0.00015 20.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 EPX73767.1 - 0.00017 21.6 0.0 0.0005 20.0 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 EPX73767.1 - 0.0005 19.1 0.0 0.0008 18.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 EPX73767.1 - 0.0031 16.7 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.1 EPX73767.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EPX73767.1 - 0.14 11.5 0.0 0.4 10.0 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DIL PF01843.14 EPX73768.1 - 6.1e-14 51.7 1.9 6.6e-13 48.4 1.3 2.5 1 1 0 1 1 1 1 DIL domain HIG_1_N PF04588.8 EPX73769.1 - 7.1e-18 64.0 0.2 9.1e-18 63.7 0.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region tRNA-synt_2b PF00587.20 EPX73770.1 - 2e-25 89.3 0.0 1.2e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EPX73770.1 - 2.8e-13 49.8 2.5 5.1e-13 48.9 1.7 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Cnl2_NKP2 PF09447.5 EPX73770.1 - 0.081 12.6 0.1 0.25 11.0 0.1 2.0 1 0 0 1 1 1 0 Cnl2/NKP2 family protein Muted PF14942.1 EPX73770.1 - 0.096 12.5 1.9 0.18 11.6 1.3 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein H-kinase_dim PF02895.9 EPX73770.1 - 0.098 13.0 0.2 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain tRNA-synt_His PF13393.1 EPX73770.1 - 0.12 11.3 0.1 0.5 9.3 0.0 1.9 2 0 0 2 2 2 0 Histidyl-tRNA synthetase PseudoU_synth_1 PF01416.15 EPX73771.1 - 6.5e-31 106.8 0.0 3.9e-18 65.8 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase zf-Mss51 PF13824.1 EPX73772.1 - 3.2e-20 71.7 1.2 6.6e-20 70.7 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 START PF01852.14 EPX73772.1 - 0.054 12.8 0.1 0.078 12.2 0.1 1.2 1 0 0 1 1 1 0 START domain YL1_C PF08265.6 EPX73772.1 - 0.059 12.9 0.2 0.19 11.3 0.1 1.8 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain PS_Dcarbxylase PF02666.10 EPX73773.1 - 9.8e-69 230.7 0.0 3e-68 229.1 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Sds3 PF08598.6 EPX73774.1 - 1.9e-23 83.0 11.4 2.7e-23 82.6 7.9 1.1 1 0 0 1 1 1 1 Sds3-like IncA PF04156.9 EPX73774.1 - 0.0073 15.9 10.5 0.015 14.9 7.3 1.5 1 0 0 1 1 1 1 IncA protein DUF342 PF03961.8 EPX73774.1 - 0.37 9.1 4.5 0.58 8.5 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) OmpH PF03938.9 EPX73774.1 - 9.6 6.1 10.2 0.93 9.4 3.7 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Cyt-b5 PF00173.23 EPX73775.1 - 4.3e-11 42.4 0.0 5.6e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain VEFS-Box PF09733.4 EPX73775.1 - 0.15 11.7 0.5 0.21 11.2 0.4 1.2 1 0 0 1 1 1 0 VEFS-Box of polycomb protein Kei1 PF08552.6 EPX73776.1 - 4e-37 127.7 19.4 8.8e-35 120.0 13.5 2.1 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 RNA_pol PF00940.14 EPX73777.1 - 2.8e-154 513.4 0.0 3.8e-154 513.0 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EPX73777.1 - 6.4e-62 209.6 0.0 9.6e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PH_4 PF15404.1 EPX73778.1 - 2.2e-28 99.0 5.2 2.6e-25 89.0 2.6 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EPX73778.1 - 3.8e-07 30.2 3.2 0.017 15.3 0.2 3.4 2 1 0 2 2 2 2 PH domain Spo7_2_N PF15407.1 EPX73778.1 - 0.00012 21.4 0.1 0.00036 19.9 0.1 1.8 1 0 0 1 1 1 1 Sporulation protein family 7 PH_9 PF15410.1 EPX73778.1 - 0.00076 19.6 0.4 0.11 12.6 0.0 3.7 4 0 0 4 4 4 1 Pleckstrin homology domain PH_6 PF15406.1 EPX73778.1 - 0.0043 17.0 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain ESCRT-II PF05871.7 EPX73778.1 - 0.021 14.7 0.3 0.34 10.8 0.0 2.5 2 0 0 2 2 2 0 ESCRT-II complex subunit eIF-5a PF01287.15 EPX73779.1 - 2.1e-26 91.6 0.3 2.9e-26 91.1 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EPX73779.1 - 0.00011 21.7 1.4 0.00011 21.7 1.0 2.2 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 EPX73779.1 - 0.007 16.2 0.1 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain GFO_IDH_MocA PF01408.17 EPX73780.1 - 8.9e-23 81.0 0.0 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPX73780.1 - 1.9e-18 66.3 0.0 3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EPX73780.1 - 4.7e-06 26.9 0.0 8.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.14 EPX73780.1 - 0.099 13.1 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Glyco_hydro_17 PF00332.13 EPX73781.1 - 2e-32 112.4 0.1 4.9e-32 111.1 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Lung_7-TM_R PF06814.8 EPX73782.1 - 8.1e-77 258.0 21.2 9.9e-77 257.7 14.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor POT1 PF02765.12 EPX73783.1 - 2.9e-14 53.2 0.0 8.5e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 TIG PF01833.19 EPX73784.1 - 2.7e-13 49.7 0.8 2.7e-13 49.7 0.6 2.1 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.2 EPX73784.1 - 1.1e-12 48.1 0.0 2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPX73784.1 - 1.1e-12 47.0 0.1 4.7e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EPX73784.1 - 1e-10 41.4 0.3 1.7e-06 28.0 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPX73784.1 - 1.1e-08 35.3 0.1 1.8e-07 31.4 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPX73784.1 - 4.9e-07 29.3 0.1 0.03 14.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Arm PF00514.18 EPX73785.1 - 8.4e-15 53.9 7.9 0.00011 21.9 0.0 7.8 7 1 1 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EPX73785.1 - 3.3e-13 49.7 1.2 0.0059 16.8 0.0 5.8 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.17 EPX73785.1 - 1e-06 28.3 14.7 0.0057 16.6 0.1 7.0 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 EPX73785.1 - 2.4e-05 24.6 5.0 0.64 10.5 0.0 5.7 5 1 1 6 6 6 2 HEAT-like repeat Cnd1 PF12717.2 EPX73785.1 - 0.0068 16.2 17.5 0.014 15.2 1.0 4.8 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DASH_Spc34 PF08657.5 EPX73785.1 - 0.015 15.0 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Spc34 Atx10homo_assoc PF09759.4 EPX73785.1 - 0.09 12.5 8.8 0.14 11.9 0.2 4.0 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain WD40 PF00400.27 EPX73786.1 - 1.4e-27 94.5 8.1 3.6e-06 26.6 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EPX73786.1 - 8.6e-07 28.8 0.2 0.016 14.9 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EPX73786.1 - 0.00062 19.3 1.0 13 5.5 0.0 3.7 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat MgsA_C PF12002.3 EPX73787.1 - 4.1e-56 189.2 0.0 5.7e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EPX73787.1 - 2.1e-15 57.0 0.1 3.5e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPX73787.1 - 2.4e-12 46.3 0.0 5.2e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EPX73787.1 - 5.7e-08 32.5 0.1 3.4e-07 30.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EPX73787.1 - 7.4e-07 28.7 0.0 0.0096 15.4 0.0 2.3 1 1 1 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.1 EPX73787.1 - 2.6e-06 27.5 0.1 0.00032 20.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPX73787.1 - 2.6e-05 24.3 0.5 0.00068 19.7 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPX73787.1 - 3.6e-05 23.6 0.0 5.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EPX73787.1 - 7.9e-05 21.5 0.0 0.00043 19.1 0.0 1.9 1 1 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 EPX73787.1 - 0.00025 20.0 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EPX73787.1 - 0.00044 20.2 0.0 0.00079 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EPX73787.1 - 0.00075 18.7 0.1 0.51 9.4 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EPX73787.1 - 0.00085 19.0 0.1 0.0025 17.5 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain ResIII PF04851.10 EPX73787.1 - 0.0036 17.1 0.3 1.5 8.5 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_13 PF13166.1 EPX73787.1 - 0.0047 15.4 0.2 0.16 10.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPX73787.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EPX73787.1 - 0.017 14.8 0.0 3.9 7.1 0.0 2.5 1 1 1 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 EPX73787.1 - 0.018 14.2 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activ_2 PF14532.1 EPX73787.1 - 0.023 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.1 EPX73787.1 - 0.027 14.1 0.0 0.3 10.7 0.0 2.0 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_3 PF07726.6 EPX73787.1 - 0.032 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EPX73787.1 - 0.035 13.3 0.2 0.54 9.4 0.0 2.2 1 1 1 2 2 2 0 PhoH-like protein PEPCK_ATP PF01293.15 EPX73787.1 - 0.047 12.2 0.0 0.079 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_17 PF13207.1 EPX73787.1 - 0.053 14.3 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPX73787.1 - 0.054 13.1 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EPX73787.1 - 0.065 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EPX73787.1 - 0.091 13.0 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EPX73787.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 EPX73787.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EPX73787.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EPX73787.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EPX73787.1 - 0.17 11.4 0.1 0.51 9.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EPX73788.1 - 3.2e-21 75.5 0.0 5.3e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase CDT1 PF08839.6 EPX73788.1 - 1.4e-10 41.3 1.1 1.4e-10 41.3 0.7 1.7 2 0 0 2 2 2 1 DNA replication factor CDT1 like Helicase_C PF00271.26 EPX73788.1 - 5.6e-10 38.9 0.0 4.6e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EPX73788.1 - 5.9e-10 39.5 2.6 1.6e-09 38.2 1.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Mit_ribos_Mrp51 PF11709.3 EPX73789.1 - 2.9e-22 79.3 0.2 3.4e-22 79.0 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit TyeA PF09059.5 EPX73789.1 - 0.076 12.9 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 TyeA RPAP2_Rtr1 PF04181.8 EPX73791.1 - 1.8e-15 56.7 2.4 1.8e-15 56.7 1.6 1.8 2 0 0 2 2 2 1 Rtr1/RPAP2 family Toxin_13 PF07822.6 EPX73791.1 - 0.05 13.5 1.0 0.12 12.3 0.7 1.6 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein Sec20 PF03908.8 EPX73792.1 - 2.2e-28 97.7 2.4 2.4e-28 97.6 0.6 1.9 2 0 0 2 2 2 1 Sec20 GDI PF00996.13 EPX73792.1 - 0.0048 15.2 0.2 0.0062 14.8 0.1 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor DUF1647 PF07801.6 EPX73792.1 - 0.13 11.7 0.5 0.21 11.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) DUF4207 PF13904.1 EPX73792.1 - 1.3 8.2 4.7 1.9 7.8 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Cys_Met_Meta_PP PF01053.15 EPX73793.1 - 1.6e-57 194.5 0.0 3.9e-57 193.2 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPX73793.1 - 2.1e-06 26.9 0.0 3.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPX73793.1 - 0.0091 14.7 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V B3_4 PF03483.12 EPX73794.1 - 1.8e-22 79.6 0.0 2.9e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EPX73794.1 - 1.7e-17 63.0 0.0 1.2e-14 53.8 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetase B5 domain Ribosomal_L13 PF00572.13 EPX73795.1 - 2.3e-26 92.3 0.1 5.6e-26 91.1 0.0 1.7 3 0 0 3 3 3 1 Ribosomal protein L13 GTP_EFTU PF00009.22 EPX73796.1 - 4.1e-57 192.6 0.0 7.4e-57 191.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPX73796.1 - 3.2e-36 123.4 0.0 8.7e-36 122.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPX73796.1 - 3.8e-16 58.9 1.1 1.1e-15 57.4 0.7 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EPX73796.1 - 6.9e-05 22.4 0.3 0.00022 20.8 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EPX73796.1 - 0.0014 18.5 0.5 0.0043 16.9 0.4 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RRM_1 PF00076.17 EPX73797.1 - 6.6e-16 57.6 0.0 8.3e-16 57.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX73797.1 - 9.8e-13 47.8 0.0 1.3e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX73797.1 - 7e-06 25.8 0.0 9.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPX73797.1 - 0.0047 16.7 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif zf-C3HC4_3 PF13920.1 EPX73798.1 - 0.00012 21.7 10.3 0.0002 20.9 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPX73798.1 - 0.00012 21.8 4.3 0.00012 21.8 3.0 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EPX73798.1 - 0.00019 21.0 9.9 0.0003 20.4 5.9 2.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPX73798.1 - 0.0026 17.5 8.8 0.014 15.1 6.3 2.1 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPX73798.1 - 0.0041 17.1 10.2 0.0077 16.2 6.1 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX73798.1 - 0.023 14.3 12.5 0.051 13.2 7.3 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Turandot PF07240.6 EPX73798.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot zf-RING_UBOX PF13445.1 EPX73798.1 - 3.2 7.5 7.3 0.39 10.4 0.3 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Ribosomal_L34e PF01199.13 EPX73799.1 - 1.9e-38 130.5 0.9 2.6e-38 130.1 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Pkinase PF00069.20 EPX73800.1 - 8e-65 218.5 0.0 1.2e-64 217.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73800.1 - 2.7e-28 98.7 0.0 4.8e-28 97.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX73800.1 - 0.0002 20.3 0.5 0.46 9.4 0.0 2.4 2 1 0 2 2 2 2 Kinase-like APH PF01636.18 EPX73800.1 - 0.0078 15.9 0.0 2.7 7.6 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF3317 PF11779.3 EPX73801.1 - 3.9e-15 55.0 5.6 9.3e-15 53.8 3.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3317) Tmemb_18A PF09771.4 EPX73801.1 - 0.017 15.0 1.0 0.023 14.6 0.5 1.3 1 1 0 1 1 1 0 Transmembrane protein 188 MARVEL PF01284.18 EPX73801.1 - 0.043 13.6 2.7 0.054 13.3 1.9 1.0 1 0 0 1 1 1 0 Membrane-associating domain TRIC PF05197.8 EPX73801.1 - 0.064 12.6 2.0 0.34 10.3 0.1 2.0 1 1 1 2 2 2 0 TRIC channel Glyco_hydro_47 PF01532.15 EPX73802.1 - 1.5e-130 435.9 0.1 1.8e-130 435.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pribosyltran PF00156.22 EPX73803.1 - 1.9e-17 63.1 0.0 2.4e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPX73803.1 - 0.01 15.0 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Metallophos PF00149.23 EPX73804.1 - 9.5e-18 64.3 0.6 1.7e-17 63.4 0.1 1.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPX73804.1 - 5.5e-05 23.0 0.0 9.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_transf_20 PF00982.16 EPX73806.1 - 4e-157 523.5 0.3 6e-157 522.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EPX73806.1 - 1.9e-83 278.9 0.0 3.1e-83 278.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EPX73806.1 - 1.5e-06 27.9 0.0 0.0034 16.9 0.0 2.8 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase PIP5K PF01504.13 EPX73807.1 - 3.4e-84 281.9 0.1 5e-84 281.3 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase polyprenyl_synt PF00348.12 EPX73808.1 - 0.0021 16.9 0.5 0.042 12.6 0.4 2.1 1 1 0 1 1 1 1 Polyprenyl synthetase COQ9 PF08511.6 EPX73810.1 - 5.5e-28 96.2 0.2 8.9e-28 95.6 0.1 1.3 1 0 0 1 1 1 1 COQ9 Med9 PF07544.8 EPX73810.1 - 0.085 12.6 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ER PF01133.12 EPX73811.1 - 6.4e-17 61.1 0.1 8e-17 60.8 0.1 1.1 1 0 0 1 1 1 1 Enhancer of rudimentary Peptidase_S10 PF00450.17 EPX73812.1 - 2.2e-127 425.6 0.1 2.2e-127 425.6 0.1 1.6 2 0 0 2 2 2 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EPX73812.1 - 0.033 14.0 0.0 0.25 11.2 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Neur_chan_memb PF02932.11 EPX73812.1 - 6 6.6 4.6 11 5.7 3.2 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Aldo_ket_red PF00248.16 EPX73813.1 - 4.7e-46 156.8 0.0 5.4e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FA_hydroxylase PF04116.8 EPX73814.1 - 8.5e-08 32.5 21.7 8.5e-08 32.5 15.0 2.0 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EPX73814.1 - 0.071 13.1 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region RRM_1 PF00076.17 EPX73815.1 - 6.6e-44 147.4 0.1 1.4e-16 59.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX73815.1 - 2.2e-34 117.2 0.1 4.3e-14 52.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX73815.1 - 1.1e-25 89.2 0.0 2.3e-09 36.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EPX73815.1 - 4.3e-12 46.1 0.0 1.5e-11 44.3 0.0 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.1 EPX73815.1 - 2.4e-07 30.3 0.1 0.083 12.6 0.0 3.7 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EPX73815.1 - 0.00013 21.7 0.1 0.03 14.1 0.0 2.9 3 0 0 3 3 3 1 RNA binding motif DUF1866 PF08952.6 EPX73815.1 - 0.0069 15.9 0.0 2.6 7.5 0.0 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF1866) Histone PF00125.19 EPX73816.1 - 7.8e-26 90.0 0.0 1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPX73816.1 - 1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.22 EPX73817.1 - 3.5e-63 209.3 2.3 2.2e-23 81.7 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3411 PF11891.3 EPX73817.1 - 0.08 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3411) Ureidogly_hydro PF04115.7 EPX73818.1 - 3.5e-46 156.5 0.0 4e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Polysacc_deac_1 PF01522.16 EPX73819.1 - 2.5e-15 56.1 0.0 3.8e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase MutL_C PF08676.6 EPX73820.1 - 4.9e-27 94.2 0.0 9.7e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EPX73820.1 - 2.3e-24 85.1 0.0 5.1e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EPX73820.1 - 9.1e-13 48.0 2.1 1e-12 47.9 0.4 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EPX73820.1 - 1.6e-12 47.1 0.2 4.1e-12 45.8 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Apc4 PF12896.2 EPX73821.1 - 5e-40 137.0 3.2 7.6e-40 136.4 0.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EPX73821.1 - 6.3e-07 28.8 0.0 5.6e-06 25.7 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.1 EPX73821.1 - 0.003 17.0 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 PQQ-like domain Tox-PL PF15644.1 EPX73821.1 - 0.099 13.3 0.0 0.24 12.1 0.0 1.7 1 0 0 1 1 1 0 Papain fold toxin 1 CPSF_A PF03178.10 EPX73822.1 - 2.3e-88 296.3 0.0 1.1e-87 294.1 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EPX73822.1 - 1.1e-64 218.4 0.0 2.1e-64 217.5 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_S2 PF00318.15 EPX73823.1 - 6.4e-42 143.1 0.1 5.3e-21 74.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 HATPase_c PF02518.21 EPX73824.1 - 1.7e-25 88.9 0.0 3.4e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPX73824.1 - 1.5e-20 73.2 0.0 5e-20 71.5 0.0 2.0 2 0 0 2 2 1 1 Response regulator receiver domain HisKA PF00512.20 EPX73824.1 - 6.4e-17 61.3 0.0 1.8e-16 59.8 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.20 EPX73824.1 - 9.3e-13 47.9 0.0 2.4e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain AAA_16 PF13191.1 EPX73824.1 - 2.6e-09 37.3 0.0 8.5e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain GAF_3 PF13492.1 EPX73824.1 - 2.8e-07 30.6 0.1 8.6e-07 29.1 0.1 1.9 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 EPX73824.1 - 8.1e-06 26.3 0.0 1.9e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.12 EPX73824.1 - 2.2e-05 23.6 0.0 5.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase NACHT PF05729.7 EPX73824.1 - 8.4e-05 22.2 0.0 0.00031 20.4 0.0 2.0 1 0 0 1 1 1 1 NACHT domain GAF PF01590.21 EPX73824.1 - 0.00042 20.4 0.0 0.00094 19.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain TPR_8 PF13181.1 EPX73824.1 - 0.0035 16.9 0.0 0.066 13.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_17 PF13207.1 EPX73824.1 - 0.011 16.5 0.0 0.064 14.0 0.0 2.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EPX73824.1 - 0.018 15.2 0.1 0.11 12.6 0.0 2.5 2 0 0 2 2 1 0 AAA domain MobB PF03205.9 EPX73824.1 - 0.019 14.7 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EPX73824.1 - 0.033 14.4 0.0 0.17 12.2 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 EPX73824.1 - 0.036 14.0 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EPX73824.1 - 0.042 12.7 0.2 0.084 11.7 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EPX73824.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EPX73824.1 - 0.053 12.9 0.0 0.19 11.1 0.0 2.0 2 0 0 2 2 1 0 AAA-like domain PAS_3 PF08447.6 EPX73824.1 - 0.059 13.4 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 PAS fold TGF_beta_GS PF08515.7 EPX73824.1 - 0.067 12.5 0.4 0.18 11.1 0.3 1.7 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif ABC_tran PF00005.22 EPX73824.1 - 0.071 13.3 0.5 0.27 11.5 0.0 2.2 2 0 0 2 2 1 0 ABC transporter AAA_29 PF13555.1 EPX73824.1 - 0.13 11.8 2.5 0.086 12.3 0.1 2.0 2 0 0 2 2 1 0 P-loop containing region of AAA domain DUF2075 PF09848.4 EPX73824.1 - 0.14 11.0 0.0 0.3 10.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EPX73824.1 - 0.26 10.6 0.1 0.73 9.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EPX73824.1 - 0.29 9.8 0.0 0.54 8.9 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Rep_fac_C PF08542.6 EPX73825.1 - 2e-19 69.3 0.7 5.7e-19 67.8 0.1 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPX73825.1 - 4e-18 65.6 0.4 1.8e-15 56.9 0.1 2.7 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 EPX73825.1 - 6.9e-18 65.1 0.0 1.3e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EPX73825.1 - 4.4e-11 42.1 0.0 1e-08 34.3 0.0 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EPX73825.1 - 2.5e-06 27.6 1.7 0.046 13.8 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.1 EPX73825.1 - 1.8e-05 24.6 0.0 5.6e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EPX73825.1 - 4.1e-05 22.6 0.0 7.2e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 EPX73825.1 - 6.8e-05 22.5 0.5 0.00056 19.5 0.4 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPX73825.1 - 6.9e-05 22.0 0.0 0.00033 19.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPX73825.1 - 7.4e-05 22.8 0.0 0.00022 21.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EPX73825.1 - 0.00011 21.8 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 EPX73825.1 - 0.00023 20.7 0.6 0.00041 19.9 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_30 PF13604.1 EPX73825.1 - 0.0029 17.1 0.2 0.2 11.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EPX73825.1 - 0.0083 15.7 0.3 0.016 14.7 0.2 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EPX73825.1 - 0.0098 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase zf-C2H2_2 PF12756.2 EPX73825.1 - 0.011 15.8 0.4 0.13 12.3 0.3 2.2 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AAA_25 PF13481.1 EPX73825.1 - 0.011 15.1 0.3 0.06 12.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EPX73825.1 - 0.018 14.8 0.6 0.11 12.1 0.0 2.6 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 EPX73825.1 - 0.018 14.5 0.2 0.18 11.2 0.0 2.3 1 1 0 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.16 EPX73825.1 - 0.026 13.6 0.0 0.14 11.3 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EPX73825.1 - 0.032 13.6 0.0 0.079 12.3 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 EPX73825.1 - 0.035 13.7 0.0 0.096 12.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EPX73825.1 - 0.044 13.2 0.6 3.7 6.9 0.0 2.4 1 1 0 2 2 2 0 AAA-like domain ResIII PF04851.10 EPX73825.1 - 0.072 12.9 0.1 1.5 8.6 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EPX73825.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Gly_transf_sug PF04488.10 EPX73826.1 - 0.11 12.9 0.1 0.42 11.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase sugar-binding region containing DXD motif tRNA-synt_1g PF09334.6 EPX73827.1 - 2.8e-107 358.7 0.1 4.6e-107 358.0 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EPX73827.1 - 2e-19 69.0 0.1 3e-11 42.0 0.0 3.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EPX73827.1 - 1.1e-08 34.5 0.1 8.2e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EPX73827.1 - 0.02 13.5 0.5 0.03 12.9 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (K) Omptin PF01278.15 EPX73827.1 - 0.044 12.8 1.0 0.073 12.1 0.7 1.2 1 0 0 1 1 1 0 Omptin family DNA_pol_E_B PF04042.11 EPX73828.1 - 1.9e-45 154.7 0.3 2.5e-45 154.3 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Enamelin PF15362.1 EPX73829.1 - 0.84 7.6 8.8 0.91 7.5 6.1 1.0 1 0 0 1 1 1 0 Enamelin Alpha_GJ PF03229.8 EPX73829.1 - 1.8 8.9 12.3 2.4 8.4 8.5 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J YchF-GTPase_C PF06071.8 EPX73830.1 - 5.1e-36 122.3 0.4 1.3e-35 121.0 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EPX73830.1 - 3.5e-14 52.7 0.0 9.8e-14 51.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPX73830.1 - 4.3e-05 22.8 0.0 0.0001 21.6 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.1 EPX73830.1 - 0.017 15.4 0.1 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EPX73830.1 - 0.017 15.9 0.1 0.19 12.5 0.0 2.6 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 EPX73830.1 - 0.02 13.6 0.0 0.042 12.6 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_14 PF13173.1 EPX73830.1 - 0.02 14.7 0.0 0.067 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EPX73830.1 - 0.09 12.5 0.0 6.1 6.6 0.0 2.7 2 1 1 3 3 3 0 Dynamin family RPAP1_N PF08621.5 EPX73830.1 - 0.14 11.7 1.1 0.27 10.8 0.7 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal UPF0029 PF01205.14 EPX73831.1 - 7.3e-31 106.1 0.2 1.2e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EPX73831.1 - 6.7e-11 42.0 2.1 2.4e-09 37.0 1.5 2.7 1 1 0 1 1 1 1 RWD domain Cytochrome-c551 PF10643.4 EPX73831.1 - 0.15 11.3 0.7 0.19 10.9 0.5 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Alpha-amylase PF00128.19 EPX73832.1 - 9.2e-62 209.2 0.0 9.2e-62 209.2 0.0 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF187 PF02638.10 EPX73832.1 - 0.0067 15.3 0.1 0.01 14.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 DUF1966 PF09260.6 EPX73832.1 - 0.0085 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.1 EPX73832.1 - 0.018 13.9 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Pkinase PF00069.20 EPX73834.1 - 7.1e-61 205.6 0.0 4.8e-40 137.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73834.1 - 5.5e-28 97.7 0.0 5.5e-22 78.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPX73834.1 - 7.8e-05 21.7 0.0 0.00033 19.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPX73834.1 - 0.0071 16.1 0.1 0.46 10.1 0.0 2.9 2 1 0 3 3 3 1 Phosphotransferase enzyme family Response_reg PF00072.19 EPX73834.1 - 0.014 15.4 0.1 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 Response regulator receiver domain Seadorna_VP7 PF07387.6 EPX73834.1 - 0.085 11.6 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 PAS PF00989.19 EPX73834.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 PAS fold Kdo PF06293.9 EPX73834.1 - 0.15 11.0 0.0 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Met_10 PF02475.11 EPX73835.1 - 1.1e-70 237.3 0.0 1.5e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.11 EPX73835.1 - 0.0063 15.4 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MOZART2 PF12926.2 EPX73835.1 - 0.16 11.6 0.1 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated UPF0300 PF08594.5 EPX73836.1 - 1.2e-74 249.9 4.4 2.2e-74 249.0 3.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) Acyl_transf_1 PF00698.16 EPX73837.1 - 5e-17 62.2 0.0 7.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain ubiquitin PF00240.18 EPX73838.1 - 1.3e-34 117.4 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EPX73838.1 - 1.2e-29 101.6 11.4 1.8e-29 101.0 7.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EPX73838.1 - 4.8e-20 71.0 0.7 6.5e-20 70.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPX73838.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPX73838.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EPX73838.1 - 0.0047 16.7 0.1 0.01 15.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPX73838.1 - 0.0089 16.1 0.1 0.01 16.0 0.1 1.2 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EPX73838.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EPX73838.1 - 0.17 10.1 0.5 4.3 5.5 0.2 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Fer2_3 PF13085.1 EPX73838.1 - 0.28 11.0 2.0 1.3 8.8 1.4 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-DHHC PF01529.15 EPX73838.1 - 0.71 9.2 4.7 1.1 8.6 3.2 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Iso_dh PF00180.15 EPX73839.1 - 5e-80 269.0 0.0 6.1e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HECT PF00632.20 EPX73840.1 - 7.9e-92 307.7 0.1 1.1e-91 307.3 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EPX73840.1 - 4.8e-34 115.8 21.4 1.7e-11 43.7 3.7 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EPX73840.1 - 8.3e-17 60.8 0.1 2.6e-16 59.2 0.1 1.9 1 0 0 1 1 1 1 C2 domain SKG6 PF08693.5 EPX73841.1 - 1.8e-08 33.5 0.9 5.1e-08 32.0 0.7 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.2 EPX73841.1 - 0.0023 17.1 3.3 0.0034 16.6 2.3 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SCF PF02404.10 EPX73841.1 - 0.012 14.8 0.3 0.012 14.8 0.2 1.8 2 0 0 2 2 2 0 Stem cell factor Mid2 PF04478.7 EPX73841.1 - 0.021 14.2 1.0 0.021 14.2 0.7 2.7 2 1 1 3 3 3 0 Mid2 like cell wall stress sensor TMEM154 PF15102.1 EPX73841.1 - 0.026 14.2 0.0 0.026 14.2 0.0 2.6 2 0 0 2 2 2 0 TMEM154 protein family CcoS PF03597.10 EPX73841.1 - 2.2 7.7 4.6 3.8 7.0 3.2 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type zinc_ribbon_6 PF14599.1 EPX73842.1 - 1.4e-24 85.6 4.6 1.4e-24 85.6 3.2 4.2 4 1 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 EPX73842.1 - 3.7e-15 55.8 24.9 3.7e-15 55.8 17.3 4.6 3 1 1 4 4 4 2 CHY zinc finger zf-RING_2 PF13639.1 EPX73842.1 - 2.4e-08 33.6 8.9 2.4e-08 33.6 6.2 4.7 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPX73842.1 - 9e-07 28.4 6.9 9e-07 28.4 4.8 6.0 2 2 4 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPX73842.1 - 2.5e-06 27.3 4.4 2.5e-06 27.3 3.0 5.6 2 2 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX73842.1 - 3.8e-05 23.3 6.9 3.8e-05 23.3 4.8 7.0 3 3 2 5 5 5 1 zinc-RING finger domain Prok-RING_1 PF14446.1 EPX73842.1 - 0.011 15.4 1.6 0.011 15.4 1.1 6.5 4 2 2 6 6 6 0 Prokaryotic RING finger family 1 Pkinase PF00069.20 EPX73843.1 - 1.5e-73 247.1 0.0 2.2e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73843.1 - 2.9e-33 115.0 0.0 4e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX73843.1 - 4.8e-07 29.0 0.1 1.6e-06 27.3 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EPX73843.1 - 0.00078 19.2 0.2 0.18 11.4 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAT1 PF09770.4 EPX73843.1 - 2 6.5 13.7 1 7.5 6.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 WW PF00397.21 EPX73844.1 - 5.8e-05 22.8 1.3 0.00011 21.9 0.9 1.5 1 0 0 1 1 1 1 WW domain NMU PF02070.10 EPX73844.1 - 8.5 5.9 8.1 20 4.8 0.1 3.4 4 0 0 4 4 4 0 Neuromedin U TGT PF01702.13 EPX73845.1 - 3.6e-34 118.0 0.0 4.3e-33 114.5 0.0 2.1 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Phosducin PF02114.11 EPX73845.1 - 1.2e-06 27.4 1.3 1.6e-06 27.0 0.9 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EPX73845.1 - 0.00033 20.3 0.0 0.00078 19.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin DHHA2 PF02833.9 EPX73846.1 - 4e-20 72.2 0.5 7.2e-20 71.4 0.4 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EPX73846.1 - 4.7e-14 52.2 0.2 1.3e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 DHH family GARS_N PF02844.10 EPX73846.1 - 0.069 13.6 0.0 1.2 9.5 0.0 2.6 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, N domain UPF0081 PF03652.10 EPX73846.1 - 0.092 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) Vps54 PF07928.7 EPX73847.1 - 9.3e-31 106.7 0.7 9.3e-31 106.7 0.5 2.4 2 0 0 2 2 2 1 Vps54-like protein GKAP PF03359.8 EPX73847.1 - 0.0064 16.1 0.9 0.014 15.0 0.6 1.5 1 1 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein CCG PF02754.11 EPX73847.1 - 0.17 11.8 0.1 0.64 10.0 0.0 2.0 2 0 0 2 2 2 0 Cysteine-rich domain DUF3980 PF13140.1 EPX73848.1 - 0.26 11.5 5.0 0.6 10.4 3.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3980) Aminotran_1_2 PF00155.16 EPX73849.1 - 1.6e-71 241.1 0.0 2.2e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPX73849.1 - 5.5e-06 25.3 0.0 1.4e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EPX73849.1 - 0.0017 16.7 0.0 0.0028 15.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DHHA1 PF02272.14 EPX73849.1 - 0.065 12.9 0.2 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 DHHA1 domain MFS_1 PF07690.11 EPX73850.1 - 4.4e-24 84.8 24.8 7.5e-24 84.0 17.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2919 PF11143.3 EPX73850.1 - 2.5 7.9 13.0 0.063 13.1 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2919) MFS_2 PF13347.1 EPX73851.1 - 1.5e-10 40.1 15.0 1.5e-10 40.1 10.4 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein Reticulon PF02453.12 EPX73851.1 - 0.79 9.3 9.1 0.041 13.4 2.0 2.1 2 0 0 2 2 2 0 Reticulon HEAT PF02985.17 EPX73852.1 - 1.1e-25 87.3 8.1 0.00091 19.1 0.0 10.4 10 0 0 10 10 10 6 HEAT repeat HEAT_EZ PF13513.1 EPX73852.1 - 2.1e-21 75.7 6.0 6.3e-11 42.4 0.0 10.2 11 0 0 11 11 11 1 HEAT-like repeat HEAT_2 PF13646.1 EPX73852.1 - 3.7e-20 72.0 2.3 6.8e-05 23.0 0.0 7.3 3 3 4 8 8 8 5 HEAT repeats Arm PF00514.18 EPX73852.1 - 1.5e-09 37.3 3.4 0.16 11.8 0.0 6.6 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 EPX73852.1 - 6.5e-07 29.6 0.2 0.2 12.0 0.1 5.3 3 2 4 7 7 7 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EPX73852.1 - 1.1e-05 25.2 0.7 0.001 18.9 0.0 3.6 3 1 1 4 4 4 1 Importin-beta N-terminal domain Cnd1 PF12717.2 EPX73852.1 - 2.1e-05 24.4 2.1 0.2 11.4 0.1 5.7 5 2 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EPX73852.1 - 6.2e-05 21.5 1.0 0.028 12.7 0.1 3.7 4 0 0 4 4 4 1 Adaptin N terminal region Ipi1_N PF12333.3 EPX73852.1 - 0.0011 18.9 0.2 5.6 6.9 0.0 4.5 4 0 0 4 4 3 1 Rix1 complex component involved in 60S ribosome maturation MMS19_C PF12460.3 EPX73852.1 - 0.0016 17.2 0.1 9.9 4.7 0.0 3.8 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal UNC45-central PF11701.3 EPX73852.1 - 0.0059 16.2 0.1 0.031 13.9 0.0 2.3 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 EPX73852.1 - 0.0081 15.5 0.0 6.3 6.0 0.0 4.5 3 2 1 4 4 4 1 CLASP N terminal DUF2435 PF10363.4 EPX73852.1 - 0.028 14.2 0.6 0.4 10.6 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) Cnd3 PF12719.2 EPX73852.1 - 0.057 12.4 0.0 0.24 10.3 0.0 2.1 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Aldo_ket_red PF00248.16 EPX73853.1 - 1.2e-46 158.8 0.0 1.7e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family SSB PF00436.20 EPX73854.1 - 2.4e-12 46.6 0.0 3.2e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family RNA_pol_I_A49 PF06870.7 EPX73855.1 - 6.4e-109 364.0 2.3 8.4e-109 363.6 1.6 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor MH2 PF03166.9 EPX73855.1 - 0.088 12.6 0.3 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 MH2 domain TPR_11 PF13414.1 EPX73856.1 - 4.5e-10 39.0 11.5 1.6e-07 30.8 2.0 2.6 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EPX73856.1 - 2.1e-06 27.0 10.2 0.15 11.7 0.7 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPX73856.1 - 3.1e-05 23.5 10.2 0.18 11.8 0.9 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPX73856.1 - 0.0021 17.9 5.5 0.023 14.6 0.3 2.9 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPX73856.1 - 0.0053 17.3 4.8 1.9 9.2 0.9 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EPX73856.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 SHNi-TPR MIT PF04212.13 EPX73856.1 - 0.16 11.9 2.0 0.44 10.4 0.0 2.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 EPX73856.1 - 0.27 11.4 6.6 1.3 9.1 3.2 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4398 PF14346.1 EPX73856.1 - 3.4 7.7 9.6 1.1 9.2 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) Gly_transf_sug PF04488.10 EPX73857.1 - 2.6e-21 75.9 0.1 4.9e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF912 PF06024.7 EPX73857.1 - 0.00071 19.5 4.1 0.0041 17.1 0.1 2.3 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Caps_synth PF05704.7 EPX73857.1 - 0.012 14.7 0.6 0.019 14.1 0.4 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EPX73857.1 - 0.032 12.7 1.0 0.22 9.9 0.0 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Ninjurin PF04923.7 EPX73857.1 - 0.039 13.6 2.1 0.05 13.3 0.2 2.0 2 0 0 2 2 2 0 Ninjurin COX14 PF14880.1 EPX73857.1 - 0.048 13.2 0.3 0.11 12.0 0.2 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c assembly EphA2_TM PF14575.1 EPX73857.1 - 0.068 13.5 2.1 0.4 11.1 0.5 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain UPF0560 PF10577.4 EPX73857.1 - 0.16 10.2 0.2 0.35 9.0 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 Viral_Beta_CD PF04530.7 EPX73857.1 - 0.2 11.8 1.0 5.3 7.2 0.1 2.5 2 0 0 2 2 2 0 Viral Beta C/D like family Sigma_reg_N PF13800.1 EPX73857.1 - 0.82 9.7 8.9 6.6 6.8 1.1 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF3671 PF12420.3 EPX73857.1 - 1 9.3 11.0 0.12 12.4 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function Baculo_11_kDa PF06143.6 EPX73857.1 - 2 7.8 9.4 2.5 7.5 2.0 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family EVI2A PF05399.6 EPX73857.1 - 3.1 6.9 4.4 7.9 5.6 0.4 2.5 3 0 0 3 3 3 0 Ectropic viral integration site 2A protein (EVI2A) YajC PF02699.10 EPX73857.1 - 4.9 6.9 7.9 0.29 10.8 0.6 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit DUF1180 PF06679.7 EPX73857.1 - 10 6.0 7.7 0.35 10.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) LSM PF01423.17 EPX73858.1 - 2e-19 68.8 0.0 2.4e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPX73858.1 - 3.7e-06 26.7 0.0 4.2e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF4477 PF14780.1 EPX73859.1 - 0.0016 17.8 0.2 0.15 11.4 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4477) RR_TM4-6 PF06459.7 EPX73859.1 - 1.9 8.3 5.9 2.4 7.9 4.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_DNAp_acc PF04929.7 EPX73859.1 - 7.2 5.4 10.6 11 4.9 7.3 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MatE PF01554.13 EPX73860.1 - 8.2e-53 178.3 24.7 1.4e-27 96.2 5.8 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EPX73860.1 - 1e-05 25.4 30.5 0.00033 20.4 4.8 3.3 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain ThiF PF00899.16 EPX73861.1 - 6e-08 32.5 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EPX73861.1 - 0.0087 15.6 0.0 0.035 13.6 0.0 1.9 2 0 0 2 2 2 1 MoeZ/MoeB domain DUF2706 PF10913.3 EPX73861.1 - 0.078 12.5 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) ABC_tran PF00005.22 EPX73862.1 - 8.4e-37 126.5 0.0 1.2e-18 67.6 0.0 2.4 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EPX73862.1 - 3.8e-08 33.6 8.6 0.019 14.9 0.1 3.8 2 2 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EPX73862.1 - 2.4e-07 30.1 0.3 0.0041 16.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EPX73862.1 - 2.7e-05 24.3 0.4 0.12 12.4 0.0 3.4 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EPX73862.1 - 9.8e-05 22.1 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EPX73862.1 - 0.00014 21.1 0.7 1.3 8.1 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EPX73862.1 - 0.00052 19.7 0.3 2.1 7.9 0.0 3.5 3 1 0 3 3 3 1 NACHT domain AAA_23 PF13476.1 EPX73862.1 - 0.0024 18.2 0.1 0.55 10.5 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPX73862.1 - 0.0042 17.8 0.0 1.4 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EPX73862.1 - 0.0071 15.8 0.2 0.84 9.0 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EPX73862.1 - 0.0074 16.2 0.0 5.1 7.0 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain T2SE PF00437.15 EPX73862.1 - 0.012 14.4 0.0 0.95 8.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein G-alpha PF00503.15 EPX73862.1 - 0.014 14.0 0.0 0.72 8.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit UPF0079 PF02367.12 EPX73862.1 - 0.028 14.0 0.0 3.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 EPX73862.1 - 0.032 14.7 0.0 3.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EPX73862.1 - 0.064 12.7 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EPX73862.1 - 0.068 12.5 2.1 2.3 7.5 0.0 2.6 2 1 0 2 2 2 0 AAA-like domain Pox_A32 PF04665.7 EPX73862.1 - 0.11 11.8 0.0 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Methyltransf_26 PF13659.1 EPX73863.1 - 5.5e-07 29.6 0.0 9.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPX73863.1 - 1.1e-06 28.0 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EPX73863.1 - 0.012 16.0 0.0 0.074 13.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain RE_XcyI PF09571.5 EPX73863.1 - 0.055 12.3 0.1 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 XcyI restriction endonuclease Methyltransf_31 PF13847.1 EPX73863.1 - 0.079 12.5 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Telomere_reg-2 PF10193.4 EPX73864.1 - 0.084 13.1 2.1 0.26 11.5 1.5 1.8 1 0 0 1 1 1 0 Telomere length regulation protein Proteasome PF00227.21 EPX73865.1 - 6.4e-58 195.1 0.0 8.1e-58 194.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPX73865.1 - 2.1e-14 52.5 0.0 3.7e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature NAD_kinase PF01513.16 EPX73866.1 - 4.4e-51 173.3 0.0 5.5e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EPX73866.1 - 0.00095 18.6 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Acyl_transf_1 PF00698.16 EPX73867.1 - 9.6e-72 241.9 0.0 6.2e-69 232.7 0.0 2.9 3 0 0 3 3 3 2 Acyl transferase domain MaoC_dehydratas PF01575.14 EPX73867.1 - 7.2e-32 109.3 2.5 6.5e-31 106.2 0.2 2.5 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 EPX73867.1 - 1.7e-28 98.1 0.0 4.3e-28 96.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EPX73867.1 - 1.5e-19 70.1 0.6 7.1e-19 67.9 0.0 2.5 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase Brix PF04427.13 EPX73868.1 - 9.7e-38 129.7 0.1 1.3e-37 129.2 0.1 1.2 1 0 0 1 1 1 1 Brix domain Dynein_light PF01221.13 EPX73869.1 - 2.1e-40 136.5 2.6 2.2e-40 136.5 1.4 1.3 1 1 0 1 1 1 1 Dynein light chain type 1 HTH_33 PF13592.1 EPX73869.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix DUF3306 PF11748.3 EPX73869.1 - 0.11 13.1 2.0 0.14 12.7 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Ground-like PF04155.13 EPX73869.1 - 0.2 11.9 0.9 0.9 9.8 0.5 2.1 1 1 0 1 1 1 0 Ground-like domain LRR_4 PF12799.2 EPX73870.1 - 1.6e-14 53.1 12.9 2.5e-07 30.1 0.9 5.1 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPX73870.1 - 7.7e-13 47.9 15.7 7.2e-11 41.6 1.5 4.7 4 1 1 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 EPX73870.1 - 1.4e-05 24.4 20.5 0.17 11.9 0.1 7.9 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 EPX73870.1 - 1.5e-05 24.3 14.4 5.5 7.6 0.2 7.3 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 EPX73870.1 - 0.0094 15.9 11.2 6.7 7.1 0.1 5.9 6 0 0 6 6 6 1 Leucine Rich repeat DASH_Dad1 PF08649.5 EPX73870.1 - 0.01 15.5 0.1 0.036 13.7 0.1 2.0 1 0 0 1 1 1 0 DASH complex subunit Dad1 LRR_9 PF14580.1 EPX73870.1 - 0.065 12.7 0.3 0.2 11.2 0.2 1.8 1 0 0 1 1 1 0 Leucine-rich repeat zf-CSL PF05207.8 EPX73871.1 - 6.7e-17 60.7 0.8 1.2e-16 59.8 0.5 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EPX73871.1 - 2.4e-15 56.0 1.3 5.4e-15 54.8 0.5 1.8 2 0 0 2 2 2 1 DnaJ domain SMC_Nse1 PF07574.8 EPX73871.1 - 0.032 13.8 0.1 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex HSP90 PF00183.13 EPX73872.1 - 1.2e-256 852.2 32.5 1.5e-256 851.9 22.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EPX73872.1 - 9.6e-12 44.6 0.0 1.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EPX73872.1 - 2.6e-11 43.3 0.3 2.6e-11 43.3 0.2 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4375 PF14300.1 EPX73872.1 - 9.3 6.2 11.3 25 4.8 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) EF-hand_1 PF00036.27 EPX73873.1 - 3.3e-11 41.6 1.1 9.8e-08 30.7 0.3 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EPX73873.1 - 4.3e-11 41.7 1.3 3.2e-06 26.5 0.2 3.2 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EPX73873.1 - 3.5e-09 36.6 1.6 2.3e-06 27.6 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPX73873.1 - 2e-05 23.7 2.5 0.00056 19.1 0.6 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EPX73873.1 - 0.0015 18.0 0.2 0.0083 15.7 0.0 2.3 3 0 0 3 3 3 1 EF-hand domain pair TPR_11 PF13414.1 EPX73875.1 - 2.9e-05 23.6 10.7 0.017 14.7 0.1 4.3 4 1 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 EPX73875.1 - 0.00015 21.6 6.0 0.13 12.5 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPX73875.1 - 0.0094 16.6 0.7 1.1 9.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Mgr1 PF08602.5 EPX73875.1 - 0.11 11.4 1.5 0.25 10.3 1.0 1.6 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit TPR_12 PF13424.1 EPX73875.1 - 0.23 11.4 3.4 3.6 7.6 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPX73875.1 - 3.3 8.5 8.3 1e+02 3.9 0.0 5.9 6 2 1 7 7 7 0 Tetratricopeptide repeat Flavin_Reduct PF01613.13 EPX73876.1 - 1.9e-34 118.7 0.9 3.1e-34 118.0 0.6 1.3 1 0 0 1 1 1 1 Flavin reductase like domain LMWPc PF01451.16 EPX73877.1 - 3.8e-41 140.6 0.0 4.3e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase E1-E2_ATPase PF00122.15 EPX73879.1 - 8.7e-59 198.3 5.8 8.7e-59 198.3 4.0 2.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EPX73879.1 - 1.1e-24 88.0 0.0 2.2e-24 87.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPX73879.1 - 5.8e-12 46.1 0.0 1.3e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPX73879.1 - 3.6e-10 39.1 0.0 8.1e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPX73879.1 - 0.0034 17.0 0.1 0.0034 17.0 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF843 PF05814.6 EPX73879.1 - 2 8.2 0.0 2 8.2 0.0 2.7 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) DnaJ PF00226.26 EPX73880.1 - 4.7e-20 71.0 2.4 4.7e-20 71.0 1.6 2.4 3 0 0 3 3 3 1 DnaJ domain SIMPL PF04402.9 EPX73880.1 - 0.05 13.4 3.7 0.13 12.0 2.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF541) SNase PF00565.12 EPX73880.1 - 0.061 13.5 4.9 0.16 12.2 0.4 2.6 2 1 0 2 2 2 0 Staphylococcal nuclease homologue DUF4588 PF15251.1 EPX73880.1 - 0.069 13.1 10.3 0.09 12.7 5.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4588) Ribosomal_60s PF00428.14 EPX73881.1 - 1.9e-28 98.6 13.6 2.2e-28 98.4 9.4 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Actin PF00022.14 EPX73882.1 - 2e-38 131.8 0.0 1.3e-37 129.2 0.0 2.2 1 1 0 1 1 1 1 Actin PilM_2 PF11104.3 EPX73882.1 - 0.057 12.2 0.0 0.23 10.3 0.0 1.9 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Trypan_PARP PF05887.6 EPX73882.1 - 5.7 6.7 8.3 13 5.5 5.8 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_S19 PF00203.16 EPX73883.1 - 2.8e-30 103.7 0.0 4.1e-30 103.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 EPX73883.1 - 0.053 13.5 0.6 4.6 7.3 0.6 2.1 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Methyltransf_16 PF10294.4 EPX73884.1 - 0.0062 16.0 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 EPX73884.1 - 0.0086 15.8 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain SPC25 PF06703.6 EPX73885.1 - 2.6e-29 101.8 0.0 2.9e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) KAT11 PF08214.6 EPX73885.1 - 0.064 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Histone acetylation protein MMS19_C PF12460.3 EPX73887.1 - 1.2e-79 267.9 9.8 1.2e-79 267.9 6.8 2.3 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EPX73887.1 - 1.4e-75 253.9 2.0 3.9e-75 252.5 0.4 2.6 2 1 1 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.1 EPX73887.1 - 0.05 14.1 1.4 8.4 7.0 0.1 4.8 2 1 2 4 4 4 0 HEAT-like repeat DUF3453 PF11935.3 EPX73888.1 - 1.4e-55 188.3 2.0 1.4e-55 188.3 1.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Gp_dh_C PF02800.15 EPX73888.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DUF2681 PF10883.3 EPX73889.1 - 0.64 10.2 19.0 0.13 12.4 2.5 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2681) Reo_sigmaC PF04582.7 EPX73889.1 - 0.82 8.7 19.4 0.085 12.0 3.3 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein MAD PF05557.8 EPX73889.1 - 1.3 7.0 42.9 0.19 9.7 11.2 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein APG6 PF04111.7 EPX73889.1 - 2.5 7.0 42.0 4.4 6.2 11.8 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3571 PF12095.3 EPX73889.1 - 3.7 7.8 11.4 0.27 11.4 0.7 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF3571) CENP-Q PF13094.1 EPX73889.1 - 8.5 6.3 39.3 9.8 6.1 3.4 3.5 1 1 3 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit Pcc1 PF09341.5 EPX73890.1 - 2.2e-21 75.6 0.0 2.5e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Cep57_MT_bd PF06657.8 EPX73891.1 - 5.1e-18 64.7 2.8 5.1e-18 64.7 1.9 4.5 4 1 1 5 5 5 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EPX73891.1 - 1.2e-05 25.1 7.0 1.2e-05 25.1 4.8 4.8 5 1 0 5 5 5 1 Centrosome localisation domain of PPC89 CAF1A PF12253.3 EPX73891.1 - 7.3 6.7 21.0 0.1 12.7 6.7 3.3 3 0 0 3 3 3 0 Chromatin assembly factor 1 subunit A PK PF00224.16 EPX73892.1 - 3.1e-165 548.9 3.0 4e-165 548.5 2.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EPX73892.1 - 3.7e-28 97.4 0.3 1.3e-27 95.6 0.2 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EPX73892.1 - 2.3e-06 26.6 0.4 5.6e-06 25.3 0.3 1.6 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PP-binding PF00550.20 EPX73893.1 - 3e-13 49.8 0.2 3.7e-13 49.5 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EPX73893.1 - 0.00026 20.9 0.5 0.00039 20.4 0.3 1.4 1 1 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EPX73893.1 - 0.0037 17.3 0.1 0.0048 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) Kdo_hydroxy PF11004.3 EPX73893.1 - 0.084 11.8 0.0 0.094 11.6 0.0 1.1 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase Rhodanese PF00581.15 EPX73894.1 - 1.2e-18 67.5 0.0 1.5e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain HSF_DNA-bind PF00447.12 EPX73894.1 - 0.02 15.0 0.0 0.062 13.4 0.0 1.7 2 0 0 2 2 2 0 HSF-type DNA-binding DNA_repr_REX1B PF14966.1 EPX73895.1 - 9e-09 35.5 3.1 9e-09 35.5 2.2 1.7 2 0 0 2 2 2 1 DNA repair REX1-B SBF2 PF12335.3 EPX73895.1 - 0.03 13.6 0.2 0.03 13.6 0.1 1.5 2 0 0 2 2 2 0 Myotubularin protein DUF3142 PF11340.3 EPX73895.1 - 0.047 13.3 0.4 0.13 11.9 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3142) DUF2746 PF10874.3 EPX73895.1 - 0.1 12.7 2.5 1.3 9.2 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2746) DUF1995 PF09353.5 EPX73895.1 - 0.11 12.1 0.2 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) DUF445 PF04286.7 EPX73895.1 - 0.25 10.8 6.6 0.27 10.7 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Syntaxin PF00804.20 EPX73895.1 - 1.9 8.7 12.8 1.7 8.8 5.3 2.6 1 1 1 2 2 2 0 Syntaxin DUF2203 PF09969.4 EPX73895.1 - 3.6 7.8 5.9 1.4e+02 2.6 4.1 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.7 EPX73895.1 - 5 6.9 7.6 30 4.4 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 EPX73895.1 - 5.7 7.0 7.5 14 5.7 5.1 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Vps51 PF08700.6 EPX73895.1 - 6.4 6.6 9.1 0.84 9.5 2.4 2.3 2 1 0 2 2 2 0 Vps51/Vps67 Syntaxin_2 PF14523.1 EPX73895.1 - 7.3 6.6 9.3 16 5.5 3.3 2.8 1 1 1 2 2 2 0 Syntaxin-like protein IncA PF04156.9 EPX73895.1 - 7.3 6.1 12.2 50 3.4 8.5 2.0 1 1 0 1 1 1 0 IncA protein zf-B_box PF00643.19 EPX73896.1 - 0.14 12.0 9.9 0.067 13.1 4.0 2.1 2 0 0 2 2 2 0 B-box zinc finger FYVE PF01363.16 EPX73896.1 - 0.53 10.2 7.2 0.97 9.3 5.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger DNA_RNApol_7kD PF03604.8 EPX73896.1 - 1.4 8.4 7.2 0.16 11.4 1.4 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit UvrD_C PF13361.1 EPX73897.1 - 4.2e-81 273.1 1.0 4.2e-81 273.1 0.7 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EPX73897.1 - 3.8e-67 226.8 0.2 3.8e-67 226.8 0.1 3.3 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EPX73897.1 - 1.6e-12 47.4 0.0 1.2e-11 44.6 0.0 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EPX73897.1 - 2e-12 46.6 0.0 5.8e-12 45.1 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EPX73897.1 - 4.7e-06 26.3 4.8 0.024 14.1 0.0 3.8 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 EPX73897.1 - 8.7e-06 25.2 0.0 0.00089 18.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EPX73897.1 - 0.00031 20.4 0.1 0.00031 20.4 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EPX73897.1 - 0.0022 17.6 0.0 0.038 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Memo PF01875.12 EPX73898.1 - 8.6e-91 303.6 0.4 9.7e-91 303.4 0.3 1.0 1 0 0 1 1 1 1 Memo-like protein Glyco_hydro_15 PF00723.16 EPX73899.1 - 1e-69 235.2 0.0 1e-68 231.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 DUF1147 PF06615.6 EPX73899.1 - 0.069 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) DnaJ-X PF14308.1 EPX73900.1 - 9.2e-54 181.8 0.3 9.2e-54 181.8 0.2 2.0 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EPX73900.1 - 2.1e-27 94.6 0.6 8.6e-27 92.6 0.4 2.2 1 0 0 1 1 1 1 DnaJ domain Peptidase_S46 PF10459.4 EPX73900.1 - 0.0029 16.1 7.0 0.0043 15.5 4.9 1.2 1 0 0 1 1 1 1 Peptidase S46 AKNA PF12443.3 EPX73900.1 - 0.01 15.8 4.7 0.57 10.2 0.0 2.6 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF1409 PF07197.7 EPX73900.1 - 0.19 11.8 1.9 0.51 10.4 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) PRTP PF01366.13 EPX73900.1 - 9 4.1 8.1 2.2 6.1 3.5 1.4 2 0 0 2 2 2 0 Herpesvirus processing and transport protein Hemocyanin_N PF03722.9 EPX73901.1 - 0.11 12.6 0.6 0.66 10.1 0.1 2.1 1 1 1 2 2 2 0 Hemocyanin, all-alpha domain PIG-S PF10510.4 EPX73902.1 - 9.9e-102 341.2 10.4 2e-100 336.9 7.2 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Syntaxin_2 PF14523.1 EPX73902.1 - 0.009 16.0 0.6 0.036 14.0 0.4 2.0 1 0 0 1 1 1 1 Syntaxin-like protein Cyt-b5 PF00173.23 EPX73903.1 - 1.1e-20 73.1 0.0 1.5e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CTP_transf_2 PF01467.21 EPX73904.1 - 8.3e-05 22.6 0.2 0.00033 20.7 0.1 2.1 1 1 0 1 1 1 1 Cytidylyltransferase SPOUT_MTase_2 PF14419.1 EPX73904.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.5 1 1 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Aminotran_5 PF00266.14 EPX73905.1 - 8.3e-34 116.9 0.0 1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V LDB19 PF13002.2 EPX73906.1 - 9e-37 126.4 0.6 1.4e-36 125.8 0.4 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EPX73906.1 - 3.4e-07 30.1 0.0 5.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Endonuclease_5 PF04493.9 EPX73907.1 - 6.6e-60 201.9 0.0 8e-60 201.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.11 EPX73907.1 - 0.021 13.9 0.1 0.062 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF99 PEX11 PF05648.9 EPX73908.1 - 2e-06 27.2 3.8 6.1e-05 22.3 0.2 2.4 1 1 2 3 3 3 2 Peroxisomal biogenesis factor 11 (PEX11) TCTP PF00838.12 EPX73909.1 - 3.1e-73 245.1 2.0 3.5e-73 245.0 1.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein CBS PF00571.23 EPX73910.1 - 1.1e-23 82.7 2.6 1.5e-09 37.4 0.0 4.2 4 0 0 4 4 4 4 CBS domain PMM PF03332.8 EPX73911.1 - 1.6e-112 374.4 1.7 1.9e-112 374.2 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EPX73911.1 - 0.00014 21.5 0.0 0.0007 19.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EPX73911.1 - 0.011 14.8 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAD PF12710.2 EPX73911.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPX73911.1 - 0.088 13.2 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FUSC PF04632.7 EPX73912.1 - 0.78 8.0 0.4 1.3 7.3 0.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cgr1 PF03879.9 EPX73913.1 - 1.3e-32 112.2 27.8 1.5e-32 111.9 19.3 1.0 1 0 0 1 1 1 1 Cgr1 family DUF4407 PF14362.1 EPX73913.1 - 2.6 6.9 6.7 2.7 6.8 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SWI-SNF_Ssr4 PF08549.5 EPX73913.1 - 7.3 4.7 8.6 7.7 4.6 6.0 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Tom37_C PF11801.3 EPX73913.1 - 7.4 6.4 7.6 8.2 6.2 5.2 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain dCMP_cyt_deam_1 PF00383.17 EPX73914.1 - 7.2e-17 60.9 0.1 8.7e-17 60.6 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EPX73914.1 - 3.6e-08 33.4 0.4 5.8e-06 26.3 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EPX73914.1 - 0.0046 16.3 0.5 0.13 11.5 0.0 2.0 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases SpoIIE PF07228.7 EPX73915.1 - 2.7e-10 40.2 0.0 3.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EPX73915.1 - 1e-08 34.9 0.0 0.00014 21.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EPX73915.1 - 7.1e-05 22.3 0.0 0.00026 20.4 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C FAD_binding_2 PF00890.19 EPX73916.1 - 3.7e-126 421.3 3.0 4.5e-126 421.0 2.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EPX73916.1 - 1.3e-47 160.8 0.5 1.9e-47 160.3 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 EPX73916.1 - 1.8e-06 27.2 0.7 0.011 14.8 0.0 3.6 4 0 0 4 4 4 2 Thi4 family Pyr_redox_2 PF07992.9 EPX73916.1 - 2e-06 27.8 0.0 0.0057 16.5 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPX73916.1 - 8.7e-06 24.8 1.0 0.033 13.0 1.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EPX73916.1 - 0.00074 18.5 0.7 0.0088 14.9 0.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPX73916.1 - 0.021 13.8 0.2 0.035 13.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EPX73916.1 - 0.55 8.6 2.5 1.1 7.6 0.4 2.3 3 0 0 3 3 3 0 HI0933-like protein AAA_23 PF13476.1 EPX73917.1 - 1.3e-24 87.6 0.7 1.3e-24 87.6 0.5 7.5 1 1 5 6 6 2 1 AAA domain Rad50_zn_hook PF04423.9 EPX73917.1 - 2.2e-10 39.8 0.1 2.2e-10 39.8 0.0 4.9 6 0 0 6 6 5 1 Rad50 zinc hook motif SMC_N PF02463.14 EPX73917.1 - 1.3e-09 37.5 25.7 1e-06 28.1 0.0 3.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EPX73917.1 - 2e-09 37.2 0.0 8.6e-09 35.2 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EPX73917.1 - 1.5e-06 28.3 2.1 0.00034 20.6 0.0 5.7 3 2 1 5 5 4 2 AAA domain AAA_13 PF13166.1 EPX73917.1 - 1e-05 24.2 0.1 0.00014 20.4 0.0 8.0 3 1 5 8 8 8 4 AAA domain Reo_sigmaC PF04582.7 EPX73917.1 - 0.0007 18.8 38.8 0.08 12.1 0.4 6.2 3 2 2 6 6 6 4 Reovirus sigma C capsid protein AAA_29 PF13555.1 EPX73917.1 - 0.0011 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EPX73917.1 - 0.012 15.7 0.1 0.012 15.7 0.1 4.2 6 0 0 6 6 5 0 AAA domain ABC_tran PF00005.22 EPX73917.1 - 0.033 14.4 0.0 0.033 14.4 0.0 5.6 4 3 0 4 4 2 0 ABC transporter DUF1546 PF07571.8 EPX73917.1 - 0.067 13.3 0.4 3.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) AAA_19 PF13245.1 EPX73917.1 - 0.15 11.7 0.0 0.54 10.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain MMgT PF10270.4 EPX73918.1 - 7.2e-06 26.3 1.2 1.2e-05 25.7 0.9 1.4 1 1 0 1 1 1 1 Membrane magnesium transporter AA_permease PF00324.16 EPX73919.1 - 2.5e-139 464.6 42.2 3.1e-139 464.4 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPX73919.1 - 3e-43 147.9 45.9 3.9e-43 147.5 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L16 PF00252.13 EPX73920.1 - 1.8e-32 111.9 0.2 2.3e-32 111.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e AMP-binding PF00501.23 EPX73921.1 - 4.7e-71 239.3 0.0 6.7e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPX73921.1 - 4.7e-65 218.9 0.0 9.2e-65 218.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EPX73921.1 - 2.1e-10 40.7 0.0 1.1e-09 38.3 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPX73921.1 - 4.1e-08 34.0 0.0 1.5e-07 32.2 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EPX73921.1 - 1.2e-07 31.4 0.0 2.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPX73921.1 - 2.5e-06 26.4 0.0 4.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 EPX73921.1 - 0.0016 17.3 0.1 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Condensation domain NAD_binding_10 PF13460.1 EPX73921.1 - 0.079 12.9 0.0 0.37 10.7 0.0 2.2 1 1 0 1 1 1 0 NADH(P)-binding DUF3139 PF11337.3 EPX73922.1 - 0.024 14.8 0.3 0.12 12.7 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) GATase PF00117.23 EPX73923.1 - 5.1e-37 127.1 0.0 1e-36 126.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EPX73923.1 - 3.7e-36 122.7 0.0 6.9e-36 121.8 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain Peptidase_C26 PF07722.8 EPX73923.1 - 8.6e-08 31.8 0.0 1.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 EPX73923.1 - 1.3e-06 27.5 0.0 0.00017 20.5 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Arginosuc_synth PF00764.14 EPX73923.1 - 0.00075 18.6 0.1 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EPX73923.1 - 0.0011 18.2 0.0 0.021 14.0 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EPX73923.1 - 0.0018 16.9 0.0 0.0036 15.9 0.0 1.5 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.14 EPX73923.1 - 0.0028 17.5 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family MetJ PF01340.15 EPX73923.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Met Apo-repressor, MetJ Asn_synthase PF00733.16 EPX73923.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase ATP_bind_3 PF01171.15 EPX73923.1 - 0.042 13.3 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 PP-loop family ThiI PF02568.9 EPX73923.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) PI31_Prot_C PF08577.6 EPX73924.1 - 2.2e-12 47.4 5.4 2.2e-12 47.4 3.7 2.8 1 1 1 2 2 2 1 PI31 proteasome regulator Glutaredoxin PF00462.19 EPX73925.1 - 2.9e-18 65.6 0.0 3.7e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EPX73925.1 - 0.0052 16.9 0.3 0.016 15.3 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain DUF1660 PF07874.6 EPX73925.1 - 0.013 15.8 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Prophage protein (DUF1660) DSBA PF01323.15 EPX73925.1 - 0.015 14.8 0.3 0.063 12.8 0.1 1.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF836 PF05768.9 EPX73925.1 - 0.045 14.0 0.0 0.057 13.6 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 EPX73925.1 - 0.049 13.4 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.1 EPX73925.1 - 0.06 13.3 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like GST_N_3 PF13417.1 EPX73925.1 - 0.1 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Zn_ribbon_2 PF12674.2 EPX73925.1 - 0.14 12.5 0.2 0.15 12.3 0.1 1.5 1 1 0 1 1 1 0 Putative zinc ribbon domain Acetyltransf_1 PF00583.19 EPX73926.1 - 6.8e-14 51.6 0.0 1.1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPX73926.1 - 0.0004 20.4 0.0 0.00056 20.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPX73926.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EPX73926.1 - 0.0026 17.8 0.1 0.0048 17.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPX73926.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Metallophos_2 PF12850.2 EPX73928.1 - 2.4e-16 59.9 0.0 2.8e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EPX73928.1 - 0.0061 15.9 0.0 0.048 13.0 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CTP_transf_2 PF01467.21 EPX73929.1 - 4.6e-16 59.2 0.0 5.3e-13 49.3 0.0 2.5 2 1 0 2 2 2 2 Cytidylyltransferase Thymidylat_synt PF00303.14 EPX73930.1 - 5.3e-112 373.2 0.0 7.1e-112 372.8 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase Flavoprotein PF02441.14 EPX73930.1 - 1e-42 144.8 1.1 2.1e-42 143.8 0.8 1.5 1 0 0 1 1 1 1 Flavoprotein Nop14 PF04147.7 EPX73930.1 - 0.95 7.3 7.8 1.3 6.8 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EPX73930.1 - 1.1 7.2 3.1 1.6 6.6 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF605 PF04652.11 EPX73930.1 - 3 7.1 13.9 4.3 6.6 9.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF2890 PF11081.3 EPX73930.1 - 3.2 7.7 8.8 5.6 6.9 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ribosomal_L44 PF00935.14 EPX73931.1 - 1.3e-32 111.6 9.7 1.8e-32 111.1 6.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 EPX73931.1 - 0.41 10.9 6.5 0.59 10.4 1.5 2.5 2 0 0 2 2 2 0 Ribosomal protein L33 NOB1_Zn_bind PF08772.6 EPX73931.1 - 1.8 8.4 6.3 0.52 10.1 0.1 2.3 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like AIP3 PF03915.8 EPX73932.1 - 5.1e-89 299.1 22.8 5.1e-89 299.1 15.8 3.2 3 0 0 3 3 3 1 Actin interacting protein 3 DUF1761 PF08570.5 EPX73933.1 - 5.7e-21 74.8 1.2 6.7e-21 74.6 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) MttA_Hcf106 PF02416.11 EPX73933.1 - 0.12 11.4 0.1 0.33 10.0 0.1 1.7 1 0 0 1 1 1 0 mttA/Hcf106 family Shugoshin_N PF07558.6 EPX73934.1 - 1.3e-10 40.8 7.0 1.3e-10 40.8 4.8 2.1 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EPX73934.1 - 3e-09 36.1 3.7 3e-09 36.1 2.6 2.5 2 0 0 2 2 2 1 Shugoshin C terminus Pkinase PF00069.20 EPX73935.1 - 4.5e-06 26.0 0.0 4.7e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73935.1 - 2.6e-05 23.4 0.0 5.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EPX73935.1 - 0.00029 21.0 1.0 0.0017 18.5 0.6 2.4 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 EPX73935.1 - 0.02 15.3 3.8 7.4 7.2 0.0 3.9 3 1 1 4 4 4 0 HEAT-like repeat HEAT PF02985.17 EPX73935.1 - 0.042 13.9 4.1 0.46 10.6 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Sedlin_N PF04628.8 EPX73936.1 - 9.7e-20 70.7 0.1 1.2e-19 70.5 0.1 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region zf-UBR PF02207.15 EPX73937.1 - 1e-18 66.8 9.6 1e-18 66.8 6.7 2.9 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EPX73937.1 - 7.4e-10 38.4 0.0 1.8e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Muskelin_N PF06588.6 EPX73938.1 - 1.5e-68 230.4 3.5 3.4e-68 229.2 1.2 2.1 2 0 0 2 2 2 1 Muskelin N-terminus Kelch_3 PF13415.1 EPX73938.1 - 1.8e-19 69.3 0.0 1e-06 28.7 0.0 7.0 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EPX73938.1 - 1.8e-17 62.8 3.6 8.8e-06 25.4 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EPX73938.1 - 4.6e-14 51.9 1.0 0.00015 21.6 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 EPX73938.1 - 8.4e-10 38.3 9.9 0.00085 19.3 0.2 6.1 5 1 1 6 6 6 2 Kelch motif Kelch_2 PF07646.10 EPX73938.1 - 1.4e-08 34.1 12.3 0.00042 19.9 0.7 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 EPX73938.1 - 1e-07 31.3 10.9 0.023 14.2 0.3 5.5 5 0 0 5 5 5 3 Kelch motif SUR7 PF06687.7 EPX73939.1 - 3e-32 111.9 11.1 4e-32 111.5 7.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF1625 PF07787.7 EPX73939.1 - 1.8 7.7 9.7 3.4 6.8 6.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1625) NVEALA PF14055.1 EPX73939.1 - 2.2 8.0 8.2 12 5.6 0.7 3.1 2 0 0 2 2 2 0 NVEALA protein DUF4097 PF13349.1 EPX73939.1 - 7.9 6.0 6.4 1.5 8.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) CH PF00307.26 EPX73940.1 - 5.9e-44 148.5 0.0 2.7e-24 85.2 0.0 3.0 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EPX73940.1 - 1.9e-14 53.0 0.1 5.5e-10 38.7 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain EFhand_Ca_insen PF08726.5 EPX73940.1 - 9.4e-08 31.9 0.2 1.3e-06 28.3 0.0 2.8 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF759 PF05537.6 EPX73940.1 - 0.0035 16.1 0.2 1.6 7.4 0.0 2.2 2 0 0 2 2 2 2 Borrelia burgdorferi protein of unknown function (DUF759) RasGAP_C PF03836.10 EPX73940.1 - 0.072 12.7 2.4 0.4 10.3 0.2 2.6 1 1 1 2 2 2 0 RasGAP C-terminus Seryl_tRNA_N PF02403.17 EPX73940.1 - 0.88 9.6 4.9 0.36 10.8 0.5 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.10 EPX73940.1 - 5.4 6.9 9.4 0.1 12.6 1.0 2.0 2 1 0 2 2 2 0 Fez1 Na_H_Exchanger PF00999.16 EPX73942.1 - 1.2e-76 257.7 38.2 1.5e-76 257.4 26.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YjeF_N PF03853.10 EPX73944.1 - 5e-37 127.1 0.0 6.2e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus zf-ZPR1 PF03367.8 EPX73945.1 - 1.3e-120 398.2 0.4 3.7e-59 198.4 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 EPX73945.1 - 0.013 15.2 3.5 0.49 10.1 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 EPX73945.1 - 0.036 13.7 12.1 0.71 9.6 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 OrfB_Zn_ribbon PF07282.6 EPX73945.1 - 0.038 13.6 1.4 2.5 7.8 0.0 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EPX73945.1 - 0.047 12.9 7.3 1.8 7.8 1.4 2.9 2 1 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.8 EPX73945.1 - 0.24 11.0 4.2 5 6.8 0.1 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Ribosomal_L32p PF01783.18 EPX73945.1 - 3.9 7.7 5.3 44 4.3 2.2 3.1 2 1 0 2 2 2 0 Ribosomal L32p protein family SNF2_N PF00176.18 EPX73946.1 - 1.2e-70 237.6 0.0 1e-69 234.6 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EPX73946.1 - 1.6e-44 152.0 12.3 1e-43 149.4 8.5 2.1 1 1 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EPX73946.1 - 1.4e-14 53.6 0.0 4.7e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EPX73946.1 - 2e-07 30.1 2.0 2.4e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 EPX73946.1 - 4.8e-05 23.5 0.2 0.09 12.9 0.0 3.4 3 1 0 3 3 3 2 AAA domain CDC45 PF02724.9 EPX73946.1 - 0.066 11.2 3.2 0.041 11.9 1.0 1.4 2 0 0 2 2 2 0 CDC45-like protein TFIID_20kDa PF03847.8 EPX73947.1 - 4.7e-34 116.4 2.2 4.7e-34 116.4 1.5 1.9 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EPX73947.1 - 0.00019 21.4 0.1 0.00037 20.4 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EPX73947.1 - 0.0058 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EPX73947.1 - 0.019 15.0 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Condensin2nSMC PF12422.3 EPX73947.1 - 0.072 12.8 0.8 0.15 11.8 0.1 1.9 2 1 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit ABC_tran PF00005.22 EPX73948.1 - 3.5e-35 121.2 0.0 1.3e-34 119.4 0.0 2.0 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EPX73948.1 - 2.2e-34 119.1 17.7 2.9e-34 118.7 12.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EPX73948.1 - 9.9e-08 32.2 0.9 0.006 16.5 0.0 2.8 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 EPX73948.1 - 6.7e-05 22.2 0.2 0.0052 16.0 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EPX73948.1 - 0.00012 22.1 0.1 0.0015 18.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPX73948.1 - 0.00013 22.0 0.0 0.00042 20.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EPX73948.1 - 0.00026 21.1 0.0 0.0033 17.6 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EPX73948.1 - 0.0022 17.2 0.0 0.0043 16.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EPX73948.1 - 0.0022 17.9 0.1 0.35 10.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EPX73948.1 - 0.0039 16.6 0.1 0.069 12.5 0.0 2.2 1 1 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 EPX73948.1 - 0.0045 16.4 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EPX73948.1 - 0.0052 17.6 0.0 0.01 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPX73948.1 - 0.012 15.0 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EPX73948.1 - 0.021 15.1 3.3 0.88 9.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EPX73948.1 - 0.028 14.2 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EPX73948.1 - 0.03 14.2 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 EPX73948.1 - 0.03 14.2 1.9 0.18 11.7 0.2 2.9 2 2 1 3 3 3 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EPX73948.1 - 0.037 13.7 0.0 0.097 12.3 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EPX73948.1 - 0.053 13.1 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 EPX73948.1 - 0.057 13.1 0.0 0.27 10.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EPX73948.1 - 0.063 13.5 0.0 0.22 11.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 EPX73948.1 - 0.085 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DASH_Spc34 PF08657.5 EPX73949.1 - 2.8e-24 86.1 14.8 2.7e-14 53.4 5.5 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 RuvB_C PF05491.8 EPX73949.1 - 0.064 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB C-terminus DUF342 PF03961.8 EPX73949.1 - 0.18 10.1 4.5 0.19 10.0 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Rnk_N PF14760.1 EPX73949.1 - 0.57 10.3 3.0 2.9 8.0 0.1 3.0 3 0 0 3 3 3 0 Rnk N-terminus Phage_Mu_Gam PF07352.7 EPX73949.1 - 0.78 9.2 6.2 1.5 8.3 0.1 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein zf-C4H2 PF10146.4 EPX73949.1 - 2.1 8.3 7.8 1.1 9.1 2.7 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein AAA_23 PF13476.1 EPX73949.1 - 2.4 8.4 9.2 3.1 8.0 6.4 1.2 1 0 0 1 1 1 0 AAA domain Sugarporin_N PF11471.3 EPX73949.1 - 2.7 7.7 10.5 2.7 7.6 1.2 2.8 1 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Fib_alpha PF08702.5 EPX73949.1 - 6.5 6.8 7.2 14 5.7 4.6 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family tRNA_lig_CPD PF08302.6 EPX73950.1 - 0.00039 19.7 1.3 0.00054 19.2 0.9 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain TLD PF07534.11 EPX73951.1 - 3.9e-27 94.9 0.1 4.9e-27 94.6 0.1 1.1 1 0 0 1 1 1 1 TLD W2 PF02020.13 EPX73952.1 - 6.5e-14 51.6 1.2 6.5e-14 51.6 0.8 3.3 3 1 1 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EPX73952.1 - 2e-13 49.1 21.5 1.7e-05 24.1 3.2 4.4 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EPX73952.1 - 6.4e-08 32.0 16.7 2.7e-05 23.6 2.3 3.3 1 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 EPX73952.1 - 7e-08 32.0 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EPX73952.1 - 0.001 19.1 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain HSF_DNA-bind PF00447.12 EPX73953.1 - 1.7e-36 124.5 0.6 3.6e-36 123.4 0.4 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EPX73953.1 - 2.8e-20 72.3 0.1 4.8e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Mito_carr PF00153.22 EPX73954.1 - 9.6e-67 220.7 6.5 4.7e-24 83.9 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein BolA PF01722.13 EPX73956.1 - 1.5e-20 72.9 0.0 1.8e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein DUF3124 PF11322.3 EPX73956.1 - 0.082 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) RRP14 PF15459.1 EPX73957.1 - 2.2e-15 56.4 1.6 2.2e-15 56.4 1.1 2.6 2 1 0 2 2 2 1 60S ribosome biogenesis protein Rrp14 DUF87 PF01935.12 EPX73957.1 - 0.051 13.3 4.6 0.066 13.0 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 PAS_7 PF12860.2 EPX73957.1 - 0.2 11.7 1.5 0.85 9.6 0.0 2.1 2 0 0 2 2 2 0 PAS fold HPIH PF13323.1 EPX73957.1 - 2.3 7.8 4.8 0.63 9.7 0.9 1.8 1 1 1 2 2 2 0 N-terminal domain with HPIH motif Ribosomal_S7 PF00177.16 EPX73959.1 - 4.8e-39 133.3 0.7 5.6e-39 133.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e rRNA_processing PF08524.6 EPX73960.1 - 3.9e-26 91.6 31.8 4.9e-26 91.2 22.0 1.1 1 0 0 1 1 1 1 rRNA processing SEEK1 PF15357.1 EPX73960.1 - 0.094 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 GBP_C PF02841.9 EPX73960.1 - 1 8.4 17.7 1.2 8.2 12.3 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Spore_coat_CotO PF14153.1 EPX73960.1 - 1.1 8.6 18.3 1.4 8.2 12.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO YqfD PF06898.6 EPX73960.1 - 2.6 6.6 13.4 3.1 6.4 9.3 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD PPR_3 PF13812.1 EPX73961.1 - 4.9e-05 23.2 0.0 7.4 7.1 0.0 6.0 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EPX73961.1 - 0.0012 18.7 0.9 6.2 6.8 0.1 4.9 4 1 1 5 5 5 2 PPR repeat family Tyr_Deacylase PF02580.11 EPX73962.1 - 2.4e-50 170.3 0.2 2.6e-50 170.1 0.2 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase cNMP_binding PF00027.24 EPX73964.1 - 3.3e-41 139.0 0.2 3.3e-20 71.6 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EPX73964.1 - 4.9e-07 29.0 0.9 1.3e-06 27.7 0.6 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Fork_head PF00250.13 EPX73965.1 - 2.1e-31 107.7 0.7 4.3e-31 106.8 0.5 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EPX73965.1 - 5.3e-13 48.8 0.1 1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Snf7 PF03357.16 EPX73966.1 - 6.6e-48 162.3 21.3 6.6e-48 162.3 14.8 1.5 1 1 1 2 2 2 1 Snf7 TraF_2 PF13729.1 EPX73966.1 - 0.0081 14.9 3.8 0.21 10.3 1.0 2.2 2 0 0 2 2 2 2 F plasmid transfer operon, TraF, protein Hydant_A_N PF05378.8 EPX73966.1 - 0.021 14.3 2.3 0.027 13.9 0.9 1.6 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region DUF2229 PF09989.4 EPX73966.1 - 5.6 6.3 9.5 1.8 7.9 3.8 1.9 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) ArsA_ATPase PF02374.10 EPX73967.1 - 3.5e-111 371.0 0.1 4.1e-111 370.8 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EPX73967.1 - 1.4e-15 57.2 0.2 2.7e-15 56.2 0.1 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EPX73967.1 - 2.1e-08 34.2 0.0 1.4e-07 31.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 EPX73967.1 - 1e-05 25.0 0.0 0.0013 18.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 EPX73967.1 - 3.5e-05 23.1 0.1 7.4e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 EPX73967.1 - 0.00074 18.9 0.2 0.0043 16.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EPX73967.1 - 0.0083 15.0 0.1 0.014 14.2 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain PhoH PF02562.11 EPX73967.1 - 0.0087 15.3 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein MipZ PF09140.6 EPX73967.1 - 0.015 14.4 0.2 0.043 12.8 0.1 1.7 1 1 1 2 2 2 0 ATPase MipZ YhjQ PF06564.7 EPX73967.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.4 1 1 0 1 1 1 0 YhjQ protein Zeta_toxin PF06414.7 EPX73967.1 - 0.05 12.6 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Gp37_Gp68 PF07505.6 EPX73967.1 - 0.08 12.0 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Phage protein Gp37/Gp68 IstB_IS21 PF01695.12 EPX73967.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Ctr PF04145.10 EPX73968.1 - 2.6e-28 98.8 10.3 9.5e-28 97.0 7.2 1.7 1 1 0 1 1 1 1 Ctr copper transporter family PEN-2 PF10251.4 EPX73968.1 - 0.026 14.7 1.1 0.29 11.3 0.1 2.2 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase NUC129 PF08157.6 EPX73968.1 - 0.041 13.8 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 NUC129 domain DUF3943 PF13084.1 EPX73968.1 - 0.067 12.7 0.3 0.12 11.9 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3943) HA2 PF04408.18 EPX73969.1 - 9.9e-20 70.4 0.0 9.9e-20 70.4 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPX73969.1 - 5.3e-15 55.0 0.0 2.5e-14 52.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EPX73969.1 - 1.5e-11 44.1 0.0 1.3e-10 41.1 0.0 2.6 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EPX73969.1 - 8.7e-08 31.8 0.1 2.8e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPX73969.1 - 0.0011 19.0 0.4 0.039 14.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EPX73969.1 - 0.36 10.6 0.0 0.36 10.6 0.0 4.5 6 0 0 6 6 6 0 Type III restriction enzyme, res subunit PPTA PF01239.17 EPX73971.1 - 1.5e-47 157.0 14.8 4.9e-11 41.4 0.3 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.1 EPX73971.1 - 0.073 12.5 4.5 14 5.2 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) Crystallin PF00525.13 EPX73972.1 - 0.059 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal XPC-binding PF09280.6 EPX73972.1 - 0.082 12.3 0.1 45 3.6 0.0 3.1 3 0 0 3 3 3 0 XPC-binding domain NTF2 PF02136.15 EPX73973.1 - 1.6e-07 31.6 0.0 1.9e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EPX73973.1 - 0.00058 19.6 0.0 0.00065 19.5 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Scm3 PF10384.4 EPX73974.1 - 2.2e-19 68.6 0.1 4.1e-19 67.8 0.1 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 PGPGW PF09656.5 EPX73975.1 - 0.3 10.3 9.7 1.2e+02 2.0 0.0 6.9 9 0 0 9 9 9 0 Putative transmembrane protein (PGPGW) OCD_Mu_crystall PF02423.10 EPX73976.1 - 3.7e-54 183.6 0.0 4.2e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EPX73976.1 - 2.5e-08 34.1 0.0 4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 EPX73976.1 - 0.0067 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Xan_ur_permease PF00860.15 EPX73977.1 - 3.2e-67 226.7 29.8 5.2e-67 226.0 20.7 1.3 1 0 0 1 1 1 1 Permease family MFS_1 PF07690.11 EPX73978.1 - 9.7e-42 142.9 52.6 9.7e-42 142.9 36.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPX73978.1 - 2.6e-15 55.6 24.0 3.5e-15 55.2 16.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPX73978.1 - 7.6e-15 54.4 8.3 7.6e-15 54.4 5.8 3.3 2 1 0 3 3 3 1 Sugar (and other) transporter Wzz PF02706.10 EPX73978.1 - 0.078 12.7 2.7 0.46 10.3 0.0 3.0 3 0 0 3 3 3 0 Chain length determinant protein zf-DHHC PF01529.15 EPX73979.1 - 1.8e-35 121.8 16.0 1.8e-35 121.8 10.4 1.5 1 1 0 1 1 1 1 DHHC palmitoyltransferase QueC PF06508.8 EPX73979.1 - 0.49 9.6 3.1 0.76 9.0 2.1 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC IMPDH PF00478.20 EPX73980.1 - 4.5e-138 459.9 2.7 5.5e-138 459.6 1.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EPX73980.1 - 5.1e-19 67.7 0.2 7.8e-09 35.1 0.0 2.9 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EPX73980.1 - 4.2e-08 32.4 1.1 7.6e-08 31.5 0.8 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EPX73980.1 - 2.9e-07 29.9 9.5 0.00024 20.3 6.3 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 EPX73980.1 - 3.2e-05 23.3 3.8 6.4e-05 22.3 1.2 2.4 3 0 0 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 EPX73980.1 - 0.0045 15.8 0.5 0.54 9.0 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Aldolase PF01081.14 EPX73980.1 - 0.014 14.6 0.6 0.04 13.0 0.2 1.9 1 1 0 1 1 1 0 KDPG and KHG aldolase CHB_HEX PF03173.8 EPX73980.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative carbohydrate binding domain ThiG PF05690.9 EPX73980.1 - 0.14 11.2 3.4 0.17 10.9 0.6 2.1 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG EAL PF00563.15 EPX73980.1 - 0.18 11.2 0.5 1.8 7.9 0.1 2.2 2 0 0 2 2 2 0 EAL domain Kinesin PF00225.18 EPX73981.1 - 4.4e-117 390.5 0.0 1.6e-115 385.4 0.0 2.4 2 0 0 2 2 2 2 Kinesin motor domain SurA_N_3 PF13624.1 EPX73981.1 - 0.015 15.3 0.3 1.9 8.4 0.1 2.5 2 0 0 2 2 2 0 SurA N-terminal domain Mnd1 PF03962.10 EPX73981.1 - 0.044 13.4 2.1 0.09 12.4 0.4 2.0 1 1 0 2 2 2 0 Mnd1 family CactinC_cactus PF09732.4 EPX73982.1 - 4.5e-49 165.1 0.5 4.5e-49 165.1 0.4 2.4 2 1 0 2 2 2 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 EPX73982.1 - 4.4e-35 120.6 1.1 8.2e-35 119.8 0.7 1.5 1 0 0 1 1 1 1 Conserved mid region of cactin DUF3906 PF13046.1 EPX73982.1 - 0.08 12.5 1.3 0.2 11.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) COX7a PF02238.10 EPX73983.1 - 0.0037 16.9 0.1 0.0045 16.6 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIa zf-C2H2_4 PF13894.1 EPX73984.1 - 1.5 9.2 4.0 1.7 9.1 1.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger PBP PF01161.15 EPX73985.1 - 3.6e-11 43.1 0.0 5.3e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein bZIP_1 PF00170.16 EPX73986.1 - 1.9e-07 30.9 7.5 3.6e-07 30.0 5.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPX73986.1 - 0.00018 21.2 7.5 0.00069 19.3 5.2 2.0 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EPX73986.1 - 0.11 12.8 4.6 0.23 11.7 3.2 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor mRNA_cap_enzyme PF01331.14 EPX73987.1 - 6e-58 195.7 0.1 8.4e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EPX73987.1 - 6.5e-28 97.1 0.3 1.2e-27 96.2 0.2 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EPX73987.1 - 1.9e-06 27.3 0.0 5.4e-05 22.6 0.0 2.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Ribosomal_L2_C PF03947.13 EPX73988.1 - 1.7e-33 115.2 3.5 1.9e-33 115.0 1.8 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPX73988.1 - 2.1e-15 56.4 0.0 4.6e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Oxysterol_BP PF01237.13 EPX73989.1 - 4.3e-128 426.7 0.0 4.3e-128 426.7 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.1 EPX73989.1 - 1.6e-20 72.6 7.3 1.1e-09 38.1 0.1 3.7 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPX73989.1 - 6.7e-20 71.2 2.6 3.4e-10 40.1 1.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.24 EPX73989.1 - 2.1e-14 53.5 0.1 1.9e-13 50.4 0.0 2.6 3 0 0 3 3 3 1 PH domain Ank PF00023.25 EPX73989.1 - 8.5e-14 50.5 1.4 9e-05 22.1 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EPX73989.1 - 1.9e-12 47.3 1.8 1.8e-05 25.1 0.1 3.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPX73989.1 - 3.4e-12 45.3 4.8 0.00011 22.1 0.0 4.9 3 1 1 4 4 4 2 Ankyrin repeat PH_8 PF15409.1 EPX73989.1 - 4.3e-07 29.9 0.0 1.3e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Imm29 PF15575.1 EPX73989.1 - 0.005 16.4 1.6 0.099 12.2 0.2 3.3 2 1 1 4 4 4 1 Immunity protein 29 DUF3447 PF11929.3 EPX73989.1 - 4.4 7.1 5.5 3.6 7.4 0.1 3.3 3 2 1 4 4 4 0 Domain of unknown function (DUF3447) Ribosomal_L22 PF00237.14 EPX73990.1 - 6.9e-33 112.7 0.2 1.1e-32 112.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CBF_beta PF02312.12 EPX73990.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Core binding factor beta subunit EST1 PF10374.4 EPX73991.1 - 4.2e-21 75.3 3.4 4.2e-21 75.3 2.4 2.4 2 1 0 2 2 2 1 Telomerase activating protein Est1 EST1_DNA_bind PF10373.4 EPX73991.1 - 2.9e-20 72.6 3.8 2.9e-20 72.6 2.6 2.0 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain PyrBI_leader PF08052.6 EPX73991.1 - 0.1 12.4 0.2 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 PyrBI operon leader peptide Ribosomal_L5_C PF00673.16 EPX73992.1 - 4.5e-20 71.1 0.0 6.9e-20 70.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EPX73992.1 - 1.3e-05 24.9 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Pkinase PF00069.20 EPX73993.1 - 5.2e-70 235.5 0.0 8.8e-70 234.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX73993.1 - 2e-49 167.9 0.0 1.2e-48 165.5 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EPX73993.1 - 3.1e-16 59.2 0.0 5.9e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 EPX73993.1 - 2e-15 56.3 0.0 6.2e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EPX73993.1 - 9.8e-11 41.6 0.0 2.3e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EPX73993.1 - 4.2e-08 32.4 0.0 8.4e-07 28.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EPX73993.1 - 0.012 14.4 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EPX73993.1 - 0.12 12.0 0.0 0.57 9.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family RRM_1 PF00076.17 EPX73994.1 - 4.8e-15 54.9 0.0 8.6e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX73994.1 - 2.2e-12 46.7 0.0 3.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EPX73994.1 - 1.7e-06 28.3 0.9 1.7e-06 28.3 0.6 2.9 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EPX73994.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyclin PF08613.6 EPX73995.1 - 1.2e-06 28.9 0.1 2e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EPX73995.1 - 0.017 14.7 0.4 0.041 13.4 0.3 1.8 1 1 0 1 1 1 0 Cyclin, N-terminal domain zf-H2C2_2 PF13465.1 EPX73997.1 - 9e-10 38.3 18.5 4.4e-06 26.7 1.9 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPX73997.1 - 4e-08 33.1 11.0 0.00075 19.7 2.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPX73997.1 - 1.1e-05 25.3 11.0 0.026 14.8 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Prefoldin_2 PF01920.15 EPX73998.1 - 3.2e-18 65.4 6.3 3.6e-18 65.2 4.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF2746 PF10874.3 EPX73998.1 - 0.032 14.4 0.4 0.085 13.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) RasGAP_C PF03836.10 EPX73998.1 - 0.033 13.8 0.8 0.033 13.8 0.6 1.8 2 0 0 2 2 2 0 RasGAP C-terminus FliT PF05400.8 EPX73998.1 - 0.14 12.5 2.5 8.7 6.8 0.8 2.3 2 0 0 2 2 2 0 Flagellar protein FliT DUF4407 PF14362.1 EPX73998.1 - 0.51 9.2 4.0 0.74 8.7 2.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YbaB_DNA_bd PF02575.11 EPX73998.1 - 1.7 8.5 5.3 0.78 9.6 1.4 1.9 1 1 0 2 2 2 0 YbaB/EbfC DNA-binding family XhlA PF10779.4 EPX73998.1 - 2.6 8.0 8.8 0.31 10.9 1.3 2.1 2 0 0 2 2 2 0 Haemolysin XhlA FliJ PF02050.11 EPX73998.1 - 4 7.5 10.4 0.25 11.4 0.3 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein HSCB_C PF07743.8 EPX73998.1 - 4 7.9 6.1 3.7 8.0 0.1 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain FlxA PF14282.1 EPX73998.1 - 5.2 7.0 9.3 0.93 9.4 0.3 2.2 2 0 0 2 2 2 0 FlxA-like protein Cortex-I_coil PF09304.5 EPX73998.1 - 6.4 6.8 8.9 12 5.9 0.3 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil DivIC PF04977.10 EPX73998.1 - 7 6.2 8.0 1.1 8.8 0.2 2.5 2 1 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 EPX73998.1 - 9.6 6.0 13.1 0.17 11.7 1.5 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fis1_TPR_C PF14853.1 EPX73999.1 - 1.4e-16 60.0 2.3 2.3e-16 59.4 1.6 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EPX73999.1 - 7.1e-11 41.2 0.1 1.1e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EPX73999.1 - 0.00017 21.2 0.4 0.00096 18.8 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPX73999.1 - 0.00023 21.0 0.3 0.005 16.7 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPX73999.1 - 0.0003 21.1 0.1 0.0029 18.0 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPX73999.1 - 0.00035 20.8 1.9 0.00048 20.3 0.4 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPX73999.1 - 0.00095 19.4 0.6 0.0016 18.7 0.3 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPX73999.1 - 0.0068 17.0 0.1 0.013 16.1 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPX73999.1 - 0.013 15.1 0.5 0.029 13.9 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 EPX73999.1 - 0.019 15.0 1.1 0.72 10.0 0.2 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EPX73999.1 - 0.021 14.9 1.1 8.5 6.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPX73999.1 - 0.067 12.8 1.0 0.18 11.4 0.5 1.7 1 1 2 3 3 3 0 TPR repeat TPPK_C PF12555.3 EPX73999.1 - 0.25 11.1 2.5 0.49 10.1 1.8 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal EF-hand_4 PF12763.2 EPX74000.1 - 6.9e-42 141.4 0.0 4.4e-39 132.4 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 EPX74000.1 - 1.5e-36 125.9 3.4 8.6e-36 123.4 2.4 1.9 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.27 EPX74000.1 - 1.3e-05 24.0 1.4 0.0002 20.4 1.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EPX74000.1 - 0.00022 20.7 0.3 0.00046 19.7 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPX74000.1 - 0.0012 18.5 0.9 0.13 12.2 0.8 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EPX74000.1 - 0.0018 18.3 0.2 0.022 14.8 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair Prefoldin_2 PF01920.15 EPX74000.1 - 0.0073 16.0 3.5 0.36 10.6 0.8 2.2 2 0 0 2 2 2 1 Prefoldin subunit Lzipper-MIP1 PF14389.1 EPX74000.1 - 0.036 14.1 1.7 11 6.2 0.5 2.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF641 PF04859.7 EPX74000.1 - 0.066 12.9 0.5 2.4 7.9 0.1 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 EPX74000.1 - 0.079 12.4 2.0 5.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.6 EPX74000.1 - 0.2 11.3 2.1 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.3 EPX74000.1 - 0.23 11.2 4.3 3.3 7.5 0.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cep57_MT_bd PF06657.8 EPX74000.1 - 0.35 10.8 3.0 2.3 8.2 0.3 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Borrelia_lipo_1 PF05714.6 EPX74000.1 - 0.88 8.6 4.5 1.2 8.2 2.1 2.0 2 1 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein IncA PF04156.9 EPX74000.1 - 0.95 9.0 4.0 18 4.8 2.5 2.1 1 1 1 2 2 2 0 IncA protein Pox_A_type_inc PF04508.7 EPX74000.1 - 9.4 6.3 7.6 9.4 6.3 0.3 3.1 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat Ribosomal_L10 PF00466.15 EPX74001.1 - 1.5e-18 66.5 0.0 2.5e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Sedlin_N PF04628.8 EPX74002.1 - 5.6e-46 155.6 0.4 6.3e-46 155.5 0.3 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EPX74002.1 - 1e-10 41.4 0.1 5e-10 39.2 0.1 1.8 1 1 1 2 2 2 1 Sybindin-like family RNA_pol_Rpb5_N PF03871.9 EPX74002.1 - 0.02 15.2 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain RNA_polI_A34 PF08208.6 EPX74003.1 - 5.9e-20 71.7 12.5 5.9e-20 71.7 8.7 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF2992 PF11208.3 EPX74003.1 - 0.51 10.2 13.6 0.89 9.4 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) SR-25 PF10500.4 EPX74003.1 - 3.7 6.9 28.1 0.53 9.7 12.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1510 PF07423.6 EPX74003.1 - 8.3 5.7 28.5 6.3 6.0 10.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) LSM PF01423.17 EPX74004.1 - 2e-17 62.4 0.4 2.4e-17 62.2 0.3 1.1 1 0 0 1 1 1 1 LSM domain PP1_inhibitor PF05361.7 EPX74004.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor Xpo1 PF08389.7 EPX74005.1 - 8.8e-27 93.8 5.6 1.7e-26 92.9 0.1 3.5 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EPX74005.1 - 4.5e-11 42.5 0.3 2.1e-10 40.3 0.2 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain AMP-binding PF00501.23 EPX74006.1 - 7.1e-86 288.2 0.0 9.5e-86 287.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPX74006.1 - 0.057 14.3 0.1 0.18 12.8 0.1 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain eIF3g PF12353.3 EPX74007.1 - 1.4e-44 151.1 1.8 2e-44 150.5 1.3 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EPX74007.1 - 6.8e-18 64.0 0.0 1.4e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74007.1 - 2.2e-13 49.9 0.0 5e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74007.1 - 1.1e-07 31.5 0.0 3.3e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S4e PF00900.15 EPX74007.1 - 0.095 12.3 0.7 0.69 9.6 0.2 2.1 2 0 0 2 2 2 0 Ribosomal family S4e RRM_1 PF00076.17 EPX74008.1 - 1.2e-13 50.4 0.0 2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74008.1 - 5.2e-13 48.7 0.0 9.3e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74008.1 - 0.16 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EPX74009.1 - 4.3e-23 80.2 14.9 7.4e-09 35.1 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EPX74009.1 - 0.0031 15.7 3.2 0.28 9.2 0.1 3.1 2 1 0 3 3 3 2 Nucleoporin Nup120/160 WD40 PF00400.27 EPX74010.1 - 6e-18 63.9 0.4 1.4e-09 37.4 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Ribosomal_L2_C PF03947.13 EPX74010.1 - 0.085 12.6 0.0 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 Ribosomal Proteins L2, C-terminal domain Me-amine-dh_H PF06433.6 EPX74010.1 - 0.13 10.8 0.0 1.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) zf-U1 PF06220.7 EPX74011.1 - 4.7e-11 42.0 0.7 9.9e-11 41.0 0.5 1.6 1 0 0 1 1 1 1 U1 zinc finger zf-Dof PF02701.10 EPX74011.1 - 0.037 13.9 0.4 0.07 13.0 0.3 1.4 1 0 0 1 1 1 0 Dof domain, zinc finger UCH PF00443.24 EPX74012.1 - 2.9e-59 200.3 0.1 4.3e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPX74012.1 - 1.9e-20 73.5 0.3 4.5e-20 72.2 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EpuA PF11772.3 EPX74012.1 - 0.011 15.1 0.1 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta zf-CHY PF05495.7 EPX74013.1 - 5.7e-17 61.6 29.5 3.8e-15 55.8 11.5 3.3 3 0 0 3 3 3 2 CHY zinc finger Ski_Sno PF02437.12 EPX74013.1 - 0.0093 15.5 2.4 0.01 15.4 0.3 2.1 2 0 0 2 2 2 1 SKI/SNO/DAC family Cytochrom_c3_2 PF14537.1 EPX74013.1 - 0.37 11.1 0.1 0.37 11.1 0.1 3.6 3 1 0 3 3 3 0 Cytochrome c3 Cys_rich_KTR PF14205.1 EPX74013.1 - 0.68 9.4 9.8 0.62 9.5 0.3 4.4 3 1 0 3 3 3 0 Cysteine-rich KTR HypA PF01155.14 EPX74013.1 - 0.75 9.5 0.0 0.75 9.5 0.0 3.7 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Cytochrome_C7 PF14522.1 EPX74013.1 - 9.7 5.9 20.3 0.47 10.1 0.2 3.7 3 1 0 3 3 3 0 Cytochrome c7 DUF572 PF04502.8 EPX74014.1 - 2.8e-46 158.2 7.4 3.8e-46 157.7 4.5 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF572) zf-RING_3 PF14369.1 EPX74014.1 - 7.1e-05 22.7 3.3 0.14 12.1 0.4 2.4 2 0 0 2 2 2 2 zinc-finger PPR_2 PF13041.1 EPX74015.1 - 2.1e-20 72.4 1.6 9.1e-15 54.3 0.1 3.6 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.15 EPX74015.1 - 0.00094 19.0 9.3 0.14 12.1 0.3 4.5 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.2 EPX74015.1 - 0.004 16.5 0.0 0.3 10.5 0.0 2.8 2 0 0 2 2 2 1 PPR repeat Apc3 PF12895.2 EPX74015.1 - 0.025 14.7 1.6 0.73 10.0 0.0 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_3 PF13812.1 EPX74015.1 - 0.031 14.5 1.2 3.5 8.1 0.0 4.1 4 0 0 4 4 4 0 Pentatricopeptide repeat domain RNA_pol_Rpb1_5 PF04998.12 EPX74015.1 - 0.059 12.6 0.3 0.08 12.1 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Ribosomal_L30_N PF08079.7 EPX74016.1 - 5.4e-24 83.9 16.5 1e-23 83.1 11.4 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EPX74016.1 - 4e-20 71.1 1.7 7.6e-20 70.2 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_S11 PF00411.14 EPX74017.1 - 7.8e-41 138.6 1.3 9.3e-41 138.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S9 PF00380.14 EPX74018.1 - 1.6e-38 131.6 0.6 1.8e-38 131.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Exo70 PF03081.10 EPX74018.1 - 0.13 11.0 0.3 0.16 10.6 0.2 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Pkinase PF00069.20 EPX74019.1 - 8.3e-65 218.5 0.0 1.1e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74019.1 - 3e-23 82.1 0.0 5.3e-23 81.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX74019.1 - 0.066 12.9 0.2 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease PF00324.16 EPX74020.1 - 6.2e-54 183.1 34.9 7.6e-54 182.8 24.2 1.1 1 0 0 1 1 1 1 Amino acid permease Fn_bind PF02986.9 EPX74020.1 - 0.52 9.8 3.6 0.62 9.6 1.3 2.0 2 0 0 2 2 2 0 Fibronectin binding repeat Mhr1 PF12829.2 EPX74021.1 - 1.7e-21 75.8 0.2 2.9e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Atg14 PF10186.4 EPX74022.1 - 6.9e-15 54.7 2.8 1.4e-14 53.7 2.0 1.5 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Phi-29_GP4 PF05464.6 EPX74022.1 - 0.039 13.8 1.0 0.081 12.8 0.7 1.5 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) LDB19 PF13002.2 EPX74023.1 - 5.4e-55 185.8 0.0 8.8e-55 185.1 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EPX74023.1 - 3.1e-05 23.8 0.1 5.8e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EPX74023.1 - 0.00089 19.3 0.0 0.28 11.3 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain FYVE PF01363.16 EPX74024.1 - 2.9e-15 55.9 9.9 5.3e-15 55.0 6.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 EPX74024.1 - 1.7 8.6 13.0 3.2 7.7 9.0 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger GTP_EFTU PF00009.22 EPX74025.1 - 7.3e-60 201.6 0.4 1e-59 201.1 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPX74025.1 - 4.9e-26 90.7 0.0 1.2e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPX74025.1 - 1e-18 67.1 1.2 2.4e-18 65.9 0.8 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EPX74025.1 - 1.2e-06 28.0 0.3 2.7e-06 26.9 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EPX74025.1 - 3e-05 23.9 0.0 5.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPX74025.1 - 0.00076 19.9 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Alba PF01918.16 EPX74025.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Alba LSM PF01423.17 EPX74026.1 - 2e-16 59.3 0.0 2.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain Ribosomal_L18e PF00828.14 EPX74027.1 - 1.1e-12 48.4 0.5 1.8e-12 47.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Nop52 PF05997.7 EPX74028.1 - 4.7e-61 205.9 3.7 5.8e-61 205.6 2.6 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.3 EPX74028.1 - 0.11 12.2 0.1 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Clathrin_lg_ch PF01086.12 EPX74029.1 - 1.1e-54 185.8 12.8 1.2e-54 185.6 8.8 1.0 1 0 0 1 1 1 1 Clathrin light chain FliD_C PF07195.7 EPX74029.1 - 0.0049 16.2 0.3 0.0065 15.7 0.2 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus ApoO PF09769.4 EPX74029.1 - 0.11 12.2 1.3 0.18 11.5 0.9 1.3 1 0 0 1 1 1 0 Apolipoprotein O DUF2346 PF09803.4 EPX74029.1 - 1.4 8.8 7.9 0.72 9.7 0.6 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2346) ABC_membrane PF00664.18 EPX74030.1 - 1e-44 153.0 8.2 1.3e-44 152.6 5.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EPX74030.1 - 1.3e-30 106.4 0.0 4.2e-30 104.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EPX74030.1 - 6.9e-05 22.1 0.0 0.00013 21.2 0.0 1.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DEAD PF00270.24 EPX74030.1 - 0.07 12.6 0.1 0.44 10.0 0.1 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase SbcCD_C PF13558.1 EPX74030.1 - 0.12 12.3 0.4 0.77 9.7 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 EPX74030.1 - 0.16 10.5 0.1 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class CDC37_N PF03234.9 EPX74031.1 - 3.9e-52 177.1 14.5 3.9e-52 177.1 10.1 2.7 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EPX74031.1 - 3.6e-39 134.0 5.2 1.1e-38 132.4 3.6 1.8 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EPX74031.1 - 1.1e-21 76.4 0.1 1.1e-21 76.4 0.1 2.9 2 1 0 2 2 2 1 Cdc37 C terminal domain Exo_endo_phos PF03372.18 EPX74032.1 - 4e-31 108.8 0.0 5e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family KH_1 PF00013.24 EPX74033.1 - 0.00037 20.0 0.0 0.016 14.8 0.0 3.0 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EPX74033.1 - 0.097 12.3 0.0 0.66 9.6 0.0 2.5 2 0 0 2 2 2 0 KH domain Apc13p PF05839.6 EPX74034.1 - 1.4e-26 92.3 0.4 1.9e-26 91.8 0.3 1.2 1 0 0 1 1 1 1 Apc13p protein RhoGAP PF00620.22 EPX74035.1 - 2.3e-42 144.1 0.1 8.3e-42 142.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EPX74035.1 - 4.8e-18 64.9 23.3 6.4e-09 35.7 4.8 2.4 2 0 0 2 2 2 2 LIM domain DUF904 PF06005.7 EPX74035.1 - 0.018 15.2 0.1 0.06 13.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF3450 PF11932.3 EPX74035.1 - 0.052 12.8 3.7 0.051 12.8 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Mst1_SARAH PF11629.3 EPX74035.1 - 0.086 12.6 3.9 0.073 12.9 0.3 2.4 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF1364 PF07102.7 EPX74035.1 - 0.65 9.9 11.6 1.8 8.5 4.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1364) DUF972 PF06156.8 EPX74035.1 - 0.78 10.1 6.0 0.33 11.3 1.0 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF972) ApbA PF02558.11 EPX74036.1 - 0.0058 16.0 0.0 0.82 9.1 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA RRM_1 PF00076.17 EPX74037.1 - 2.9e-07 30.0 0.0 5.7e-05 22.6 0.0 2.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74037.1 - 4.9e-06 26.4 0.0 8.2e-05 22.5 0.0 2.9 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74037.1 - 0.00014 21.6 0.0 0.0013 18.5 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Host_attach PF10116.4 EPX74037.1 - 0.8 9.9 0.0 0.8 9.9 0.0 2.7 3 0 0 3 3 3 0 Protein required for attachment to host cells Beach PF02138.13 EPX74038.1 - 1.4e-109 365.7 0.8 3.1e-109 364.5 0.6 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EPX74038.1 - 5.1e-11 42.3 0.0 1.4e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EPX74038.1 - 3.9e-07 29.6 1.8 0.0053 16.6 0.2 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat FYVE PF01363.16 EPX74038.1 - 8.7e-06 25.5 9.2 2e-05 24.4 6.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger Laminin_G_3 PF13385.1 EPX74038.1 - 5.4e-05 23.4 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily FYVE_2 PF02318.11 EPX74038.1 - 0.21 11.4 7.9 0.61 9.9 5.5 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger HypA PF01155.14 EPX74038.1 - 1.2 8.8 4.4 3.7 7.2 3.1 1.9 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Pkinase PF00069.20 EPX74039.1 - 1.2e-38 132.7 0.0 1.7e-38 132.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74039.1 - 5.3e-15 55.1 0.0 1e-14 54.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EPX74039.1 - 2.3e-06 27.5 0.0 0.0019 17.9 0.0 2.5 3 0 0 3 3 3 2 Phosphotransferase enzyme family Baculo_p24 PF05073.7 EPX74039.1 - 0.063 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein BRCT PF00533.21 EPX74040.1 - 0.0014 18.7 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain FHA PF00498.21 EPX74041.1 - 5.5e-18 64.8 0.1 2e-17 63.0 0.0 2.0 2 0 0 2 2 2 1 FHA domain Rogdi_lz PF10259.4 EPX74042.1 - 4.6e-24 84.9 2.4 4.3e-20 71.9 1.7 2.4 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein Methyltransf_12 PF08242.7 EPX74043.1 - 1.2e-15 57.8 0.0 2.3e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX74043.1 - 1.7e-15 57.1 0.0 2.1e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX74043.1 - 3.6e-13 49.3 0.0 5.4e-13 48.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX74043.1 - 7e-11 42.4 0.0 3.8e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX74043.1 - 1.1e-08 35.5 0.0 1.8e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX74043.1 - 4e-08 33.5 0.0 8.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPX74043.1 - 1.1e-05 24.9 0.0 1.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EPX74043.1 - 0.00024 21.0 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EPX74043.1 - 0.00034 19.6 0.0 0.00045 19.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Ubie_methyltran PF01209.13 EPX74043.1 - 0.00041 19.5 0.0 0.00056 19.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EPX74043.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.12 EPX74043.1 - 0.0078 15.2 0.0 0.015 14.3 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase CheR PF01739.13 EPX74043.1 - 0.0083 15.4 0.0 2.7 7.2 0.0 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain DUF2348 PF09807.4 EPX74045.1 - 6.7e-12 45.0 0.0 1.4e-11 44.0 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Elong_Iki1 PF10483.4 EPX74045.1 - 0.0023 17.3 0.0 0.0039 16.5 0.0 1.4 1 1 0 1 1 1 1 Elongator subunit Iki1 zf-DHHC PF01529.15 EPX74046.1 - 1.1e-34 119.3 6.9 1.5e-34 118.9 3.6 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF1738 PF08401.6 EPX74046.1 - 0.25 11.0 1.2 0.7 9.6 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1738) HAD PF12710.2 EPX74047.1 - 9.4e-13 48.7 0.1 1.3e-12 48.3 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPX74047.1 - 9.3e-11 42.5 0.8 5.2e-09 36.8 0.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPX74047.1 - 2.8e-10 40.1 0.7 5e-07 29.5 0.1 2.9 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EPX74047.1 - 9.7e-06 24.9 0.0 0.00012 21.2 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase HAD_2 PF13419.1 EPX74047.1 - 0.00016 21.9 0.0 0.00031 21.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EPX74047.1 - 0.0081 15.7 0.0 0.093 12.3 0.0 2.6 1 1 1 2 2 2 1 Acid Phosphatase DUF705 PF05152.7 EPX74047.1 - 0.0095 14.9 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) RCC1 PF00415.13 EPX74048.1 - 3.8e-11 43.0 9.9 0.00042 20.4 0.1 4.7 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPX74048.1 - 9.4e-07 28.2 16.9 0.00037 20.0 2.0 5.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EPX74048.1 - 1.4e-06 27.9 0.7 3.8e-06 26.5 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPX74048.1 - 0.00065 19.2 1.1 0.0015 18.1 0.7 1.6 1 0 0 1 1 1 1 F-box domain MBOAT_2 PF13813.1 EPX74049.1 - 4.7e-12 45.8 3.2 1.4e-11 44.3 2.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Sod_Fe_C PF02777.13 EPX74050.1 - 4.5e-19 68.2 1.9 2.1e-18 66.0 1.3 1.9 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain DEAD PF00270.24 EPX74052.1 - 4.5e-40 136.9 0.1 1.2e-39 135.4 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX74052.1 - 3.9e-19 68.2 0.0 2e-18 66.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EPX74052.1 - 1.4e-18 66.1 0.0 3.1e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EPX74052.1 - 6.5e-06 26.0 0.0 6.5e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EPX74052.1 - 0.0025 17.5 0.0 0.013 15.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain Nucleo_P87 PF07267.6 EPX74052.1 - 0.0096 14.6 3.3 0.012 14.3 2.3 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 DNA_pol_viral_N PF00242.12 EPX74052.1 - 0.19 10.7 6.7 0.33 9.9 4.1 1.7 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain DUF1168 PF06658.7 EPX74052.1 - 5.2 6.5 29.0 9.8 5.6 20.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) ubiquitin PF00240.18 EPX74053.1 - 2.1e-25 87.8 0.0 2.4e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPX74053.1 - 5.1e-16 58.1 0.0 5.5e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPX74053.1 - 3e-05 24.2 0.1 6.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 EPX74053.1 - 0.059 13.5 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CTDII PF01556.13 EPX74053.1 - 0.12 12.3 0.2 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 DnaJ C terminal domain DUF2232 PF09991.4 EPX74054.1 - 0.15 11.0 8.1 0.21 10.5 5.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) BOP1NT PF08145.7 EPX74055.1 - 1.7e-81 273.7 12.8 5e-80 268.9 8.9 2.3 1 1 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EPX74055.1 - 2.3e-27 93.8 16.0 1.8e-08 33.9 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_3 PF13570.1 EPX74055.1 - 0.09 13.0 0.0 1.1 9.6 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain LIM PF00412.17 EPX74056.1 - 1.3e-24 85.9 37.1 9.1e-11 41.6 5.2 3.2 3 0 0 3 3 3 3 LIM domain DUF468 PF04318.7 EPX74056.1 - 0.066 13.7 2.0 0.18 12.4 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF468) Zn_ribbon_2 PF12674.2 EPX74056.1 - 1.2 9.5 18.7 0.38 11.1 1.2 3.5 2 1 0 2 2 2 0 Putative zinc ribbon domain VPS9 PF02204.13 EPX74057.1 - 1.6e-29 101.9 0.1 3.5e-29 100.8 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EPX74057.1 - 2.3e-07 30.1 0.1 4.5e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 CUE domain Asn_synthase PF00733.16 EPX74058.1 - 1.1e-51 175.8 0.0 1.6e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EPX74058.1 - 1.5e-12 47.3 0.0 3.5e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EPX74058.1 - 2.4e-09 37.2 0.0 4.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EPX74058.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein TRI12 PF06609.8 EPX74059.1 - 1e-14 53.6 22.8 1.4e-14 53.2 15.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EPX74059.1 - 7.9e-14 51.1 44.1 7.9e-14 51.1 30.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily UPF0126 PF03458.8 EPX74059.1 - 4.7 6.8 17.0 0.085 12.4 1.2 4.2 4 1 0 4 4 4 0 UPF0126 domain DEAD PF00270.24 EPX74061.1 - 2.4e-43 147.5 0.3 5.4e-43 146.4 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX74061.1 - 8.7e-25 86.3 0.0 2.7e-24 84.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX74061.1 - 1.8e-07 31.1 0.4 7.5e-07 29.1 0.0 2.1 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPX74061.1 - 1.3e-05 24.1 0.0 1.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 EPX74061.1 - 0.0019 16.7 0.3 1.6 7.0 0.1 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EPX74061.1 - 0.0081 16.2 0.5 0.031 14.3 0.3 2.1 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 EPX74061.1 - 0.025 14.2 0.0 0.063 12.9 0.0 1.7 1 0 0 1 1 1 0 Helicase AAA PF00004.24 EPX74061.1 - 0.031 14.4 0.3 0.14 12.3 0.2 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 EPX74062.1 - 1.1e-77 260.6 0.1 2.3e-77 259.6 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74062.1 - 1.2e-37 129.4 0.3 7.4e-37 126.8 0.2 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EPX74062.1 - 1.2e-18 66.2 0.0 2.2e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EPX74062.1 - 5.3e-07 28.8 0.0 3.2e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPX74062.1 - 1.1e-06 27.8 0.1 2.5e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPX74062.1 - 0.0008 18.8 1.0 0.0017 17.7 0.7 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EPX74062.1 - 0.0023 17.7 0.0 0.065 12.9 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 EPX74062.1 - 0.0077 15.4 0.4 0.013 14.6 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EPX74062.1 - 0.037 13.3 1.4 0.14 11.4 1.0 1.9 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Lectin_leg-like PF03388.8 EPX74063.1 - 2.5e-34 118.3 0.1 3.9e-34 117.7 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family TMF_DNA_bd PF12329.3 EPX74063.1 - 0.0003 20.5 3.3 0.00069 19.3 2.3 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 EPX74063.1 - 0.0071 16.0 2.0 0.16 11.6 1.4 2.3 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Fez1 PF06818.10 EPX74063.1 - 0.054 13.5 0.8 0.089 12.8 0.6 1.3 1 0 0 1 1 1 0 Fez1 HALZ PF02183.13 EPX74063.1 - 0.11 12.2 0.2 0.29 10.8 0.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF3573 PF12097.3 EPX74063.1 - 0.41 9.2 5.1 0.63 8.5 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Prefoldin_2 PF01920.15 EPX74063.1 - 0.77 9.5 3.4 6.5 6.5 0.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit Ribosomal_L23eN PF03939.8 EPX74064.1 - 7.8e-21 73.8 7.3 7.8e-21 73.8 5.1 1.9 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EPX74064.1 - 4.6e-18 64.9 1.8 1e-17 63.8 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 HpcH_HpaI PF03328.9 EPX74064.1 - 0.018 13.9 0.1 0.36 9.6 0.0 2.1 1 1 1 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family HMGL-like PF00682.14 EPX74065.1 - 3.2e-61 207.0 0.0 4.9e-61 206.4 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EPX74065.1 - 2.8e-28 98.3 0.0 4.9e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain GST_N_2 PF13409.1 EPX74065.1 - 0.1 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TRAM_LAG1_CLN8 PF03798.11 EPX74066.1 - 7.7e-34 116.9 34.0 7.7e-34 116.9 23.6 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EPX74066.1 - 8.4e-21 73.2 0.1 2.4e-20 71.7 0.1 1.8 1 0 0 1 1 1 1 TRAM1-like protein LSM PF01423.17 EPX74067.1 - 9.2e-21 73.1 0.0 1.1e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPX74067.1 - 0.00063 19.6 0.0 0.00072 19.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SYF2 PF08231.7 EPX74068.1 - 1.1e-42 145.7 27.2 1.1e-42 145.7 18.9 1.8 2 0 0 2 2 2 1 SYF2 splicing factor Sel1 PF08238.7 EPX74069.1 - 4.2e-10 39.9 8.0 0.0013 19.3 0.5 3.5 3 0 0 3 3 3 3 Sel1 repeat DnaJ-X PF14308.1 EPX74070.1 - 1.5e-57 194.2 2.9 1.5e-57 194.2 2.0 1.8 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EPX74070.1 - 9.7e-27 92.5 1.3 9.7e-27 92.5 0.9 1.9 2 0 0 2 2 2 1 DnaJ domain Peptidase_M24 PF00557.19 EPX74071.1 - 8.3e-44 149.6 0.0 1e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EPX74071.1 - 0.00044 20.0 5.5 0.00044 20.0 3.8 1.8 2 0 0 2 2 2 1 MYND finger ATP-cone PF03477.11 EPX74071.1 - 0.021 15.2 0.2 21 5.6 0.0 3.1 3 0 0 3 3 3 0 ATP cone domain Sad1_UNC PF07738.8 EPX74072.1 - 1.3e-36 125.3 0.3 2.7e-36 124.3 0.2 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Cep57_MT_bd PF06657.8 EPX74072.1 - 0.014 15.3 0.5 0.042 13.8 0.4 1.9 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Stathmin PF00836.14 EPX74072.1 - 0.024 14.2 0.1 0.059 13.0 0.1 1.7 1 0 0 1 1 1 0 Stathmin family XPG_N PF00752.12 EPX74073.1 - 6.2e-38 129.1 0.0 1.9e-37 127.5 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EPX74073.1 - 1.5e-24 85.8 0.0 8e-24 83.5 0.0 2.4 1 0 0 1 1 1 1 XPG I-region Polysacc_synt_4 PF04669.8 EPX74074.1 - 1.6e-23 83.0 1.3 1.1e-22 80.3 0.9 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis MFS_1 PF07690.11 EPX74075.1 - 1.5e-44 152.1 40.9 1.5e-44 152.1 28.4 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX74075.1 - 1.2e-19 70.2 27.2 5.6e-14 51.5 7.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Cas_APE2256 PF09651.5 EPX74075.1 - 0.0018 17.9 0.3 2.6 7.7 0.1 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_APE2256) Mitofilin PF09731.4 EPX74076.1 - 1.4e-72 245.2 34.3 1.6e-58 198.7 22.7 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein YlqD PF11068.3 EPX74076.1 - 0.0028 17.6 2.5 0.0028 17.6 1.7 3.0 1 1 1 2 2 2 1 YlqD protein DUF1662 PF07878.6 EPX74076.1 - 0.24 11.1 3.0 1.5 8.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1662) Ric8 PF10165.4 EPX74077.1 - 5.7e-48 163.8 0.6 7.4e-48 163.4 0.4 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Orbi_VP6 PF01516.11 EPX74077.1 - 0.037 13.0 0.3 0.08 11.9 0.0 1.5 2 0 0 2 2 2 0 Orbivirus helicase VP6 PIP5K PF01504.13 EPX74078.1 - 4.9e-62 209.2 0.6 1.2e-61 208.0 0.4 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EPX74078.1 - 3.1e-24 85.4 0.0 5.6e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EPX74078.1 - 4.4e-15 55.3 12.6 4.4e-15 55.3 8.7 2.1 2 0 0 2 2 2 1 FYVE zinc finger T2SG PF08334.6 EPX74078.1 - 0.051 13.3 0.2 0.24 11.1 0.1 2.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G WD40 PF00400.27 EPX74079.1 - 2.6e-39 131.7 15.7 8.1e-11 41.3 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF1796 PF08795.5 EPX74080.1 - 0.00019 21.0 1.3 0.00039 20.0 0.9 1.4 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Gemini_mov PF01708.11 EPX74081.1 - 0.088 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Geminivirus putative movement protein UPF0300 PF08594.5 EPX74082.1 - 9.9e-65 217.4 2.2 2e-64 216.4 1.5 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) FHA PF00498.21 EPX74083.1 - 5.6e-09 35.9 0.4 1.3e-08 34.8 0.3 1.6 1 0 0 1 1 1 1 FHA domain EnY2 PF10163.4 EPX74084.1 - 1.4e-19 69.7 0.1 1.7e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 Ofd1_CTDD PF10637.4 EPX74085.1 - 2.4e-78 262.9 0.0 3.3e-73 246.0 0.0 2.4 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EPX74085.1 - 3.6e-14 53.0 0.0 8.6e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PRP1_N PF06424.7 EPX74086.1 - 1.9e-47 160.9 3.2 4.8e-47 159.6 2.2 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EPX74086.1 - 6.7e-30 100.8 9.3 0.0019 18.6 0.0 13.4 6 4 9 15 15 15 5 Tetratricopeptide repeat TPR_19 PF14559.1 EPX74086.1 - 9e-19 67.5 3.7 0.051 13.9 0.0 8.5 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPX74086.1 - 6.1e-13 49.0 1.9 0.023 15.3 0.0 7.6 6 2 1 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPX74086.1 - 1.9e-11 42.9 1.5 0.12 12.3 0.0 8.0 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPX74086.1 - 1.8e-10 40.3 1.2 0.0058 16.2 0.0 6.3 6 2 1 7 7 7 2 TPR repeat TPR_17 PF13431.1 EPX74086.1 - 2e-10 40.0 0.1 0.036 14.2 0.0 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPX74086.1 - 2e-08 33.4 0.0 0.29 10.8 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat Suf PF05843.9 EPX74086.1 - 2.2e-06 27.6 6.4 0.03 14.0 0.0 5.1 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_8 PF13181.1 EPX74086.1 - 7.2e-06 25.4 0.0 17 5.5 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPX74086.1 - 7.4e-06 26.0 0.3 4.5 7.9 0.0 6.3 7 0 0 7 7 5 2 Tetratricopeptide repeat NARP1 PF12569.3 EPX74086.1 - 3.2e-05 22.8 7.8 0.021 13.6 0.0 4.6 6 0 0 6 6 6 2 NMDA receptor-regulated protein 1 TPR_12 PF13424.1 EPX74086.1 - 0.00036 20.3 3.7 1.2 9.1 0.0 5.5 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 EPX74086.1 - 0.0096 15.8 9.5 5.8 6.8 0.1 5.1 4 2 2 6 6 6 1 Tetratricopeptide repeat DUF1675 PF07897.6 EPX74086.1 - 0.018 14.9 0.5 0.04 13.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TPR_10 PF13374.1 EPX74086.1 - 0.07 13.0 0.2 6.1 6.9 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EPX74086.1 - 0.08 11.8 29.8 0.38 9.5 0.2 5.9 3 2 2 6 6 6 0 NRDE-2, necessary for RNA interference PPTA PF01239.17 EPX74086.1 - 3.3 7.2 5.3 4.6 6.7 0.0 4.0 5 0 0 5 5 5 0 Protein prenyltransferase alpha subunit repeat UCH PF00443.24 EPX74087.1 - 2.8e-43 147.9 1.3 3.1e-43 147.8 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EPX74087.1 - 5.7e-25 86.4 1.8 6.9e-12 44.8 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 EPX74087.1 - 2.9e-21 75.3 14.4 1.1e-18 67.0 2.5 3.7 5 0 0 5 5 5 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EPX74087.1 - 7.8e-19 68.2 4.1 7.6e-18 64.9 1.0 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HBS1_N PF08938.5 EPX74087.1 - 0.01 15.9 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 0 HBS1 N-terminus UBA_4 PF14555.1 EPX74087.1 - 0.015 14.8 1.7 0.026 14.0 0.1 2.2 2 0 0 2 2 2 0 UBA-like domain CUE PF02845.11 EPX74087.1 - 0.069 12.6 2.0 0.83 9.2 0.0 3.1 3 0 0 3 3 3 0 CUE domain ThiF PF00899.16 EPX74088.1 - 5.7e-30 103.9 0.0 3.5e-29 101.3 0.0 2.3 3 0 0 3 3 3 1 ThiF family Shikimate_DH PF01488.15 EPX74088.1 - 0.0034 17.4 0.0 0.012 15.7 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EPX74088.1 - 0.14 11.5 0.0 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA LRS4 PF10422.4 EPX74089.1 - 8.4e-15 54.8 26.6 2.4e-14 53.3 18.4 1.7 1 1 0 1 1 1 1 Monopolin complex subunit LRS4 DUF848 PF05852.6 EPX74089.1 - 0.00031 20.6 5.6 0.00031 20.6 3.9 2.5 2 0 0 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) Filament PF00038.16 EPX74089.1 - 0.0075 15.7 23.3 0.14 11.5 3.5 2.6 2 1 1 3 3 3 2 Intermediate filament protein IncA PF04156.9 EPX74089.1 - 0.0095 15.5 19.7 0.032 13.8 5.7 2.6 1 1 1 2 2 2 2 IncA protein TPR_MLP1_2 PF07926.7 EPX74089.1 - 0.013 15.2 19.5 0.15 11.8 4.4 2.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EPX74089.1 - 0.021 14.6 8.7 0.021 14.6 6.0 3.9 3 1 2 5 5 5 0 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.7 EPX74089.1 - 0.04 13.7 1.3 0.73 9.7 0.1 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4200 PF13863.1 EPX74089.1 - 0.16 11.9 19.8 0.66 9.9 3.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) TMCO5 PF14992.1 EPX74089.1 - 0.21 10.7 25.7 0.0084 15.2 10.0 2.8 2 1 1 3 3 3 0 TMCO5 family Tropomyosin_1 PF12718.2 EPX74089.1 - 0.28 11.0 29.7 0.39 10.5 5.5 3.2 2 1 0 3 3 3 0 Tropomyosin like XkdW PF09636.5 EPX74089.1 - 0.69 9.8 4.3 5.5 6.9 0.3 3.0 3 1 0 3 3 2 0 XkdW protein FliJ PF02050.11 EPX74089.1 - 1 9.4 13.5 2.7 8.0 1.1 2.6 2 0 0 2 2 2 0 Flagellar FliJ protein Bap31 PF05529.7 EPX74089.1 - 2.1 7.7 16.5 3.7 6.9 1.3 2.8 1 1 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF1664 PF07889.7 EPX74089.1 - 2.3 8.0 9.0 2.6 7.8 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4140 PF13600.1 EPX74089.1 - 2.8 8.4 7.9 1.5 9.2 0.4 3.0 3 1 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) Cluap1 PF10234.4 EPX74089.1 - 4 6.5 19.0 1.2 8.3 1.5 2.8 1 1 2 3 3 3 0 Clusterin-associated protein-1 LicD PF04991.8 EPX74089.1 - 5.9 6.9 7.6 0.3 11.1 0.8 2.1 2 0 0 2 2 2 0 LicD family GrpE PF01025.14 EPX74089.1 - 5.9 6.4 11.7 0.7 9.4 1.8 2.5 2 0 0 2 2 2 0 GrpE Syntaxin-6_N PF09177.6 EPX74089.1 - 6.3 7.2 16.9 2 8.8 1.3 3.2 3 1 0 3 3 2 0 Syntaxin 6, N-terminal DUF641 PF04859.7 EPX74089.1 - 7.5 6.3 12.5 0.56 9.9 0.9 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Pkinase PF00069.20 EPX74090.1 - 9e-41 139.7 0.0 1.6e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74090.1 - 1.3e-28 99.7 0.0 2e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX74090.1 - 4.6e-05 23.2 0.0 0.00024 20.9 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPX74090.1 - 0.053 12.4 0.0 0.3 9.9 0.0 2.2 3 0 0 3 3 3 0 Kinase-like Pal1 PF08316.6 EPX74091.1 - 6.7e-14 52.5 0.3 1.1e-13 51.7 0.2 1.4 1 0 0 1 1 1 1 Pal1 cell morphology protein DUF3535 PF12054.3 EPX74092.1 - 2.9e-118 395.3 0.0 1.4e-117 393.0 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EPX74092.1 - 2.8e-71 239.7 0.1 6.1e-71 238.6 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EPX74092.1 - 2e-13 49.1 13.2 0.014 15.3 0.0 9.4 9 0 0 9 9 9 4 HEAT repeat Helicase_C PF00271.26 EPX74092.1 - 7.7e-13 48.1 0.0 1.9e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 EPX74092.1 - 6.3e-09 36.0 0.8 0.0044 17.2 0.0 6.2 4 3 0 4 4 4 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EPX74092.1 - 4.8e-06 26.8 0.1 0.22 11.9 0.0 4.2 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EPX74092.1 - 2.4e-05 24.6 11.8 3.2 8.3 0.0 8.1 8 2 1 9 9 9 1 HEAT-like repeat GED PF02212.13 EPX74092.1 - 0.008 16.0 2.3 0.83 9.5 0.2 4.2 4 0 0 4 4 4 1 Dynamin GTPase effector domain LRR_4 PF12799.2 EPX74093.1 - 1.7e-13 49.8 30.1 0.0015 18.0 0.0 9.0 2 2 7 9 9 9 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPX74093.1 - 1.1e-08 33.9 35.5 1.2 9.3 1.0 12.4 10 4 0 10 10 10 4 Leucine Rich Repeat F-box-like PF12937.2 EPX74093.1 - 8.1e-08 31.8 1.1 2.9e-07 30.1 0.7 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EPX74093.1 - 1e-07 31.2 41.6 1.8 8.8 0.0 12.1 10 3 3 13 13 13 5 Leucine Rich repeat F-box PF00646.28 EPX74093.1 - 0.0037 16.8 1.6 0.071 12.7 0.1 3.3 3 0 0 3 3 3 1 F-box domain STAS PF01740.16 EPX74093.1 - 0.0075 15.6 0.2 2.1 7.8 0.0 2.6 2 1 0 2 2 2 2 STAS domain PRANC PF09372.5 EPX74093.1 - 0.025 14.5 0.7 0.025 14.5 0.5 3.1 3 0 0 3 3 3 0 PRANC domain LRR_7 PF13504.1 EPX74093.1 - 1.9 9.0 40.0 4.4 7.9 0.0 11.3 13 1 0 13 13 13 0 Leucine rich repeat Usp PF00582.21 EPX74094.1 - 7.4e-21 74.8 0.0 1e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family tRNA-synt_1d PF00750.14 EPX74095.1 - 2.6e-87 292.9 6.5 6.5e-87 291.6 4.5 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EPX74095.1 - 3.3e-28 98.0 0.9 9.3e-28 96.5 0.1 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EPX74095.1 - 0.0011 19.4 0.1 0.0067 16.9 0.0 2.2 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain BTB PF00651.26 EPX74098.1 - 2.2e-05 24.3 0.1 0.00017 21.5 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain KH_4 PF13083.1 EPX74099.1 - 0.019 14.5 0.1 0.05 13.2 0.1 1.7 1 0 0 1 1 1 0 KH domain MMR_HSR1 PF01926.18 EPX74100.1 - 1.8e-15 56.8 0.0 2.1e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPX74100.1 - 2.3e-09 36.7 0.0 1.2e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.11 EPX74100.1 - 3.6e-05 22.9 0.0 6.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EPX74100.1 - 0.00011 21.4 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 EPX74100.1 - 0.014 14.2 0.2 0.036 12.8 0.0 1.7 1 1 1 2 2 2 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 EPX74100.1 - 0.024 14.4 1.4 0.18 11.6 0.1 2.7 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.1 EPX74100.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EPX74102.1 - 4.3e-60 201.9 0.0 2.4e-30 105.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPX74102.1 - 1.1e-46 159.4 47.9 6.9e-26 91.2 15.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_17 PF13207.1 EPX74102.1 - 4.5e-12 46.8 0.0 0.00015 22.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EPX74102.1 - 2.4e-11 44.1 5.1 0.013 15.5 0.0 5.3 3 1 1 5 5 5 3 AAA domain SMC_N PF02463.14 EPX74102.1 - 2.2e-09 36.9 9.6 1.7e-05 24.1 0.1 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPX74102.1 - 7.3e-09 35.0 1.1 0.0027 17.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EPX74102.1 - 1.3e-07 31.9 0.0 0.011 16.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPX74102.1 - 5.1e-07 29.8 0.8 0.027 14.6 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EPX74102.1 - 1.9e-06 27.5 0.5 0.048 13.1 0.0 3.5 4 0 0 4 4 3 2 AAA-like domain AAA_16 PF13191.1 EPX74102.1 - 6.7e-06 26.2 0.2 0.074 13.0 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.12 EPX74102.1 - 8.6e-05 22.4 0.2 0.078 12.7 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_33 PF13671.1 EPX74102.1 - 0.00011 22.1 0.0 0.68 9.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EPX74102.1 - 0.00014 21.1 0.0 0.24 10.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_14 PF13173.1 EPX74102.1 - 0.00041 20.2 0.1 3.2 7.6 0.0 3.8 3 1 1 4 4 3 2 AAA domain MobB PF03205.9 EPX74102.1 - 0.00068 19.3 0.1 0.98 9.1 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EPX74102.1 - 0.00095 19.1 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EPX74102.1 - 0.0011 18.5 0.1 0.2 11.0 0.1 2.7 3 0 0 3 3 2 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 EPX74102.1 - 0.0011 19.0 0.0 1.1 9.5 0.0 2.9 2 0 0 2 2 2 1 RNA helicase CobU PF02283.11 EPX74102.1 - 0.0023 17.3 0.0 0.19 11.1 0.0 2.5 2 0 0 2 2 2 1 Cobinamide kinase / cobinamide phosphate guanyltransferase ABC_ATPase PF09818.4 EPX74102.1 - 0.0026 16.4 2.2 0.82 8.1 0.1 4.2 4 1 0 4 4 4 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 EPX74102.1 - 0.0031 16.9 3.3 0.72 9.2 0.1 3.2 2 1 0 2 2 2 1 AAA domain PRK PF00485.13 EPX74102.1 - 0.0038 16.8 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Sigma54_activ_2 PF14532.1 EPX74102.1 - 0.0048 16.9 0.0 9.2 6.3 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EPX74102.1 - 0.0056 16.1 1.6 2.6 7.4 0.0 3.6 4 0 0 4 4 3 1 IstB-like ATP binding protein SbcCD_C PF13558.1 EPX74102.1 - 0.006 16.4 0.5 0.77 9.7 0.1 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EPX74102.1 - 0.0061 16.2 0.0 2.6 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 EPX74102.1 - 0.009 14.9 0.0 2.3 7.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 EPX74102.1 - 0.015 14.8 0.3 1.3 8.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EPX74102.1 - 0.015 14.3 0.0 0.59 9.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EPX74102.1 - 0.021 14.5 0.0 5.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Sigma54_activat PF00158.21 EPX74102.1 - 0.029 13.8 0.0 2.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP_bind_1 PF03029.12 EPX74102.1 - 0.031 13.8 0.4 5.4 6.4 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 EPX74102.1 - 0.043 12.6 0.4 11 4.7 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain DUF3987 PF13148.1 EPX74102.1 - 0.059 11.9 0.0 5.9 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) APS_kinase PF01583.15 EPX74102.1 - 0.064 12.9 0.1 8 6.1 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase CPT PF07931.7 EPX74102.1 - 0.091 12.3 0.0 16 5.0 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA PF00004.24 EPX74102.1 - 0.11 12.7 0.2 28 4.8 0.0 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) CoaE PF01121.15 EPX74102.1 - 0.13 11.6 0.1 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Dephospho-CoA kinase NACHT PF05729.7 EPX74102.1 - 0.14 11.8 2.8 23 4.6 0.0 4.0 4 0 0 4 4 4 0 NACHT domain CbiA PF01656.18 EPX74102.1 - 0.17 11.2 0.8 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain KaiC PF06745.8 EPX74102.1 - 0.19 10.8 1.3 6.4 5.8 0.1 2.9 3 0 0 3 3 2 0 KaiC AAA_23 PF13476.1 EPX74102.1 - 0.19 12.0 9.8 8.4 6.6 0.1 3.2 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EPX74103.1 - 1.1e-40 139.0 0.1 2.8e-40 137.7 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EPX74103.1 - 1.8e-12 47.1 2.3 5.8e-12 45.5 1.6 1.9 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 EPX74103.1 - 1.7e-06 28.0 0.0 5.4e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 EPX74103.1 - 8.3e-06 25.8 0.0 5.9e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D4 PF14578.1 EPX74103.1 - 0.00013 21.5 0.0 0.00048 19.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EPX74103.1 - 0.00079 19.3 0.0 0.014 15.3 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EPX74103.1 - 0.066 13.7 1.2 0.22 12.0 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein G-alpha PF00503.15 EPX74103.1 - 0.17 10.5 4.9 0.33 9.5 3.4 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Guanylate_cyc PF00211.15 EPX74104.1 - 2.7e-40 137.7 0.0 4.1e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_8 PF13855.1 EPX74104.1 - 1.1e-37 127.5 76.5 3.8e-07 29.7 1.2 9.1 5 2 5 10 10 10 10 Leucine rich repeat PP2C PF00481.16 EPX74104.1 - 1.3e-34 119.7 0.1 3.4e-34 118.3 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EPX74104.1 - 1.8e-32 110.4 87.0 8.6e-09 34.8 0.3 12.5 7 3 5 14 14 14 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPX74104.1 - 1.5e-17 60.9 85.6 0.029 14.3 0.1 20.1 20 2 0 20 20 20 7 Leucine Rich Repeat LRR_7 PF13504.1 EPX74104.1 - 9.9e-13 46.0 39.6 0.57 10.6 0.0 16.0 16 0 0 16 16 16 4 Leucine rich repeat RA PF00788.18 EPX74104.1 - 9.9e-10 38.7 0.0 2.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DUF2406 PF10295.4 EPX74105.1 - 6.7e-19 68.1 0.1 1.4e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) RCR PF12273.3 EPX74107.1 - 2.7e-11 44.1 2.3 6.1e-11 42.9 1.6 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF3328 PF11807.3 EPX74107.1 - 0.0027 17.4 0.1 0.0029 17.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) YwiC PF14256.1 EPX74107.1 - 0.018 15.1 0.1 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 YwiC-like protein ProRS-C_1 PF09180.6 EPX74108.1 - 1.3e-22 79.4 0.7 6.6e-22 77.2 0.2 2.2 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EPX74108.1 - 7.6e-22 77.7 0.0 4e-21 75.3 0.0 2.1 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPX74108.1 - 4.1e-19 68.3 0.0 8.3e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 EPX74108.1 - 2e-15 56.7 0.5 3.9e-15 55.7 0.3 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA_int_endo PF01974.12 EPX74109.1 - 5e-14 51.8 0.0 1.5e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain DUF3596 PF12167.3 EPX74109.1 - 0.068 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) WD40_alt PF14077.1 EPX74109.1 - 0.16 11.6 0.4 0.34 10.5 0.3 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif LCM PF04072.9 EPX74110.1 - 1.1e-23 83.7 0.0 1.7e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 EPX74110.1 - 1.3e-08 34.4 0.5 7.3e-05 22.4 0.0 4.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EPX74110.1 - 0.00044 20.3 6.6 0.46 10.7 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 EPX74110.1 - 0.001 18.5 0.5 0.19 11.3 1.0 3.4 3 0 0 3 3 3 1 Kelch motif UvdE PF03851.9 EPX74111.1 - 5.8e-108 360.1 0.0 8.2e-108 359.6 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE KilA-N PF04383.8 EPX74112.1 - 0.04 13.5 0.0 0.46 10.1 0.0 2.6 1 1 0 1 1 1 0 KilA-N domain Voltage_CLC PF00654.15 EPX74113.1 - 1.4e-88 297.3 27.6 1.4e-88 297.3 19.1 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EPX74113.1 - 1.1e-07 31.5 0.0 0.00098 18.8 0.0 2.8 2 1 0 2 2 2 2 CBS domain Glyco_transf_15 PF01793.11 EPX74114.1 - 2.9e-135 450.5 18.0 3.6e-135 450.1 12.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase 4HBT_2 PF13279.1 EPX74114.1 - 0.051 14.0 0.1 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Thioesterase-like superfamily GCV_H PF01597.14 EPX74115.1 - 4.6e-40 136.0 0.2 5.8e-40 135.7 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EPX74115.1 - 0.00059 19.4 0.3 0.001 18.6 0.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 EPX74115.1 - 0.024 14.3 0.9 0.05 13.3 0.2 1.7 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain PC_rep PF01851.17 EPX74117.1 - 5.4e-22 76.7 25.5 1.3e-05 25.1 0.1 9.0 11 0 0 11 11 11 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EPX74117.1 - 0.00075 19.7 2.3 1.5 9.1 0.1 3.8 3 1 0 3 3 3 2 HEAT repeats MOR2-PAG1_N PF14222.1 EPX74118.1 - 3.8e-100 336.1 16.8 2.8e-96 323.4 5.8 2.9 2 1 1 3 3 3 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EPX74118.1 - 3.1e-65 220.5 3.5 9.6e-65 218.9 2.4 2.0 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EPX74118.1 - 9.2e-26 89.7 4.9 1.1e-14 53.0 0.1 3.5 4 0 0 4 4 4 3 Cell morphogenesis central region Ribosomal_L27 PF01016.14 EPX74119.1 - 1e-31 108.5 2.0 1.3e-31 108.2 1.4 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein PLU-1 PF08429.6 EPX74120.1 - 8.6e-73 245.1 12.0 5.2e-70 235.9 5.7 2.2 2 0 0 2 2 2 2 PLU-1-like protein PHD PF00628.24 EPX74120.1 - 1.1e-20 73.0 51.7 3.3e-10 39.5 7.2 3.9 4 0 0 4 4 4 3 PHD-finger JmjC PF02373.17 EPX74120.1 - 1.1e-17 64.2 0.1 3.1e-17 62.8 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EPX74120.1 - 1.1e-09 38.0 0.1 4.8e-09 35.9 0.1 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 EPX74120.1 - 1.1e-06 28.6 2.9 1.1e-06 28.6 2.0 3.2 3 0 0 3 3 3 1 C5HC2 zinc finger C1_1 PF00130.17 EPX74120.1 - 5e-05 22.9 2.1 5e-05 22.9 1.4 5.3 6 0 0 6 6 6 3 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EPX74120.1 - 0.0017 17.6 36.5 0.0022 17.2 2.8 4.5 4 0 0 4 4 4 2 PHD-finger Prok-RING_1 PF14446.1 EPX74120.1 - 0.0019 17.8 1.9 0.0019 17.8 1.3 4.9 5 0 0 5 5 5 2 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EPX74120.1 - 0.016 14.5 21.2 0.041 13.1 1.1 4.2 3 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain JmjN PF02375.12 EPX74120.1 - 0.034 13.6 0.0 0.096 12.2 0.0 1.8 1 0 0 1 1 1 0 jmjN domain Hid1 PF12722.2 EPX74121.1 - 5.5e-43 146.8 42.7 8.4e-43 146.2 29.6 1.2 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein 60KD_IMP PF02096.15 EPX74122.1 - 1.9e-38 132.1 5.3 2.9e-38 131.5 3.3 1.5 2 0 0 2 2 2 1 60Kd inner membrane protein Metallophos PF00149.23 EPX74123.1 - 2.3e-44 151.1 1.8 3.7e-44 150.5 1.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SAM_decarbox PF01536.11 EPX74124.1 - 2.7e-91 305.7 0.2 3.2e-91 305.4 0.1 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase SMC_N PF02463.14 EPX74125.1 - 2.2e-71 239.6 0.0 4e-71 238.7 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPX74125.1 - 1.6e-19 70.0 0.2 8.5e-19 67.6 0.1 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EPX74125.1 - 2.2e-09 37.7 35.0 5.7e-06 26.5 0.5 5.1 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EPX74125.1 - 3.5e-05 23.2 0.0 7.7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mnd1 PF03962.10 EPX74125.1 - 0.00086 19.0 13.5 0.00086 19.0 9.3 7.6 3 2 5 8 8 8 2 Mnd1 family Reo_sigmaC PF04582.7 EPX74125.1 - 0.0029 16.8 36.2 0.0085 15.3 2.4 6.0 2 2 5 8 8 8 5 Reovirus sigma C capsid protein AAA_23 PF13476.1 EPX74125.1 - 0.61 10.3 114.0 2.4 8.4 40.5 6.3 1 1 1 2 2 2 0 AAA domain AAA_13 PF13166.1 EPX74125.1 - 3.7 5.8 99.2 0.021 13.2 12.0 6.4 3 2 3 6 6 6 0 AAA domain zf-RING_2 PF13639.1 EPX74126.1 - 9.5e-15 54.1 8.7 1.7e-14 53.3 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPX74126.1 - 2.2e-10 40.4 2.6 4.5e-10 39.5 1.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPX74126.1 - 5.9e-07 29.0 6.9 1.1e-06 28.1 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX74126.1 - 7.3e-07 28.8 6.5 1.2e-06 28.0 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPX74126.1 - 9.2e-07 28.7 7.6 1.6e-06 28.0 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPX74126.1 - 1.1e-06 28.3 1.2 2.2e-06 27.3 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EPX74126.1 - 5.8e-05 22.6 4.8 0.0001 21.9 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EPX74126.1 - 0.0054 16.2 1.9 0.012 15.1 1.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.2 EPX74126.1 - 0.084 12.9 8.6 0.16 12.0 5.9 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 EPX74126.1 - 0.1 12.6 6.6 0.19 11.7 4.6 1.5 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.3 EPX74126.1 - 0.34 10.4 2.6 0.88 9.1 1.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EPX74126.1 - 0.94 9.4 6.4 3.4 7.6 4.5 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EPX74126.1 - 1.3 8.7 6.6 2.4 7.7 4.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EPX74126.1 - 1.4 8.6 4.5 4.3 7.1 3.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger QCR10 PF09796.4 EPX74127.1 - 1.5e-21 75.7 0.3 1.5e-21 75.7 0.2 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) zf-C2H2 PF00096.21 EPX74128.1 - 3.1e-09 36.6 13.6 5.8e-05 23.1 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPX74128.1 - 2.9e-08 33.5 14.2 4.9e-07 29.7 1.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPX74128.1 - 3e-07 30.2 13.9 0.00016 21.7 0.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPX74128.1 - 0.0079 16.3 4.2 0.16 12.1 1.0 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EPX74128.1 - 0.023 14.7 3.8 0.087 12.9 2.6 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EPX74128.1 - 0.14 12.1 4.3 6.3 6.8 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EPX74128.1 - 3.1 7.6 5.2 11 5.8 0.7 2.4 1 1 1 2 2 2 0 BED zinc finger AMP-binding PF00501.23 EPX74129.1 - 2.4e-79 266.6 0.0 3.5e-79 266.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Rhomboid PF01694.17 EPX74130.1 - 1.5e-20 73.6 8.4 1e-13 51.5 1.3 2.3 2 0 0 2 2 2 2 Rhomboid family DUF336 PF03928.9 EPX74131.1 - 6.8e-23 80.9 0.0 8.6e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Ribosom_S12_S23 PF00164.20 EPX74132.1 - 7.5e-40 135.1 0.5 8.9e-40 134.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Transp_cyt_pur PF02133.10 EPX74134.1 - 7.1e-161 535.6 43.7 8.6e-161 535.3 30.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NIF PF03031.13 EPX74136.1 - 1.6e-43 148.1 0.0 2.5e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WD40 PF00400.27 EPX74137.1 - 4.6e-12 45.3 16.3 2.7e-05 23.8 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 EPX74137.1 - 1.9e-08 34.2 1.6 1.9e-08 34.2 1.1 3.1 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EPX74137.1 - 0.001 18.9 0.1 0.006 16.3 0.1 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 TPR_19 PF14559.1 EPX74137.1 - 0.029 14.6 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ACBP PF00887.14 EPX74137.1 - 0.077 12.6 0.1 15 5.3 0.0 2.5 2 0 0 2 2 2 0 Acyl CoA binding protein Prp18 PF02840.10 EPX74137.1 - 0.15 11.9 0.5 0.79 9.5 0.2 2.2 1 1 1 2 2 2 0 Prp18 domain Pkinase PF00069.20 EPX74138.1 - 1.5e-63 214.4 0.0 2.3e-63 213.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74138.1 - 9e-39 133.0 0.0 2.4e-38 131.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EPX74138.1 - 0.0066 15.5 0.2 0.013 14.5 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPX74138.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AdoHcyase PF05221.12 EPX74139.1 - 2.1e-141 469.5 0.0 2.3e-141 469.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EPX74139.1 - 2.4e-85 284.3 3.4 4.1e-85 283.6 2.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPX74139.1 - 3e-06 26.5 0.2 5.6e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EPX74139.1 - 1.9e-05 24.0 0.2 3.3e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EPX74139.1 - 0.0026 18.1 0.2 0.0055 17.1 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EPX74139.1 - 0.0064 16.4 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EPX74139.1 - 0.024 14.2 0.2 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF4448 PF14610.1 EPX74139.1 - 0.024 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) 3HCDH_N PF02737.13 EPX74139.1 - 0.028 14.0 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_transf_34 PF05637.7 EPX74140.1 - 6.3e-64 215.7 0.4 7.6e-64 215.4 0.3 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyphos_transf PF04464.9 EPX74140.1 - 0.019 13.7 0.1 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Methyltrn_RNA_3 PF02598.12 EPX74141.1 - 9.2e-55 186.0 0.0 1.1e-54 185.8 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Radical_SAM PF04055.16 EPX74142.1 - 6.8e-16 58.8 0.0 1.1e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily SHQ1 PF04925.10 EPX74143.1 - 1.2e-60 204.2 0.1 1.9e-60 203.5 0.1 1.2 1 0 0 1 1 1 1 SHQ1 protein Syntaxin PF00804.20 EPX74144.1 - 2.3e-13 50.2 11.3 3.6e-13 49.5 4.8 2.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 EPX74144.1 - 2.7e-12 46.1 0.5 2.7e-12 46.1 0.3 2.9 3 0 0 3 3 3 1 SNARE domain Sed5p PF11416.3 EPX74144.1 - 7.9e-08 31.6 1.1 7.9e-08 31.6 0.8 2.9 3 0 0 3 3 3 1 Integral membrane protein Sed5p Syntaxin-6_N PF09177.6 EPX74144.1 - 0.00023 21.5 9.5 0.0041 17.4 1.1 3.2 2 1 2 4 4 4 2 Syntaxin 6, N-terminal Syntaxin-18_N PF10496.4 EPX74144.1 - 0.00036 20.3 1.0 0.00036 20.3 0.7 3.0 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus AAA_13 PF13166.1 EPX74144.1 - 0.0046 15.4 19.8 0.0043 15.5 9.9 2.0 1 1 0 2 2 2 1 AAA domain COG5 PF10392.4 EPX74144.1 - 0.027 14.4 11.5 0.42 10.5 3.5 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 KdpD PF02702.12 EPX74144.1 - 0.031 13.4 0.4 0.21 10.6 0.0 2.2 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain DUF1664 PF07889.7 EPX74144.1 - 0.052 13.3 7.3 0.28 10.9 0.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 EPX74144.1 - 1.3 8.9 6.8 1.7 8.6 0.0 3.6 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EPX74144.1 - 3.3 7.2 9.3 3.3 7.2 0.3 2.5 2 0 0 2 2 2 0 IncA protein Cluap1 PF10234.4 EPX74144.1 - 6 5.9 14.5 0.58 9.3 4.8 2.2 1 1 0 2 2 2 0 Clusterin-associated protein-1 Transcrip_reg PF01709.15 EPX74145.1 - 6.8e-68 228.2 2.4 7.8e-68 228.0 1.7 1.0 1 0 0 1 1 1 1 Transcriptional regulator Methyltransf_31 PF13847.1 EPX74147.1 - 2.9e-14 52.9 0.4 1.2e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX74147.1 - 6.7e-13 49.1 0.2 6.1e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EPX74147.1 - 8.2e-13 48.1 0.1 2e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EPX74147.1 - 8.5e-11 41.9 0.0 1.8e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX74147.1 - 4.4e-09 36.7 0.0 1.4e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPX74147.1 - 7.5e-08 31.9 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EPX74147.1 - 1.1e-07 31.7 0.0 4.5e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX74147.1 - 1.2e-06 28.7 0.0 3.9e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain zf-C2H2_2 PF12756.2 EPX74147.1 - 4.1e-05 23.6 1.3 9.5e-05 22.4 0.9 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) PRMT5 PF05185.11 EPX74147.1 - 5.1e-05 22.3 0.1 6.2e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.4 EPX74147.1 - 9.8e-05 21.8 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 EPX74147.1 - 0.00023 20.8 0.1 0.00052 19.6 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 FtsJ PF01728.14 EPX74147.1 - 0.00025 21.0 0.0 0.00049 20.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 EPX74147.1 - 0.00027 20.1 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EPX74147.1 - 0.00078 18.6 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EPX74147.1 - 0.0011 19.4 0.1 0.0035 17.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EPX74147.1 - 0.0029 16.3 0.0 0.004 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.9 EPX74147.1 - 0.0069 15.5 0.1 0.023 13.8 0.0 1.9 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EPX74147.1 - 0.0084 15.7 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain zf-Di19 PF05605.7 EPX74147.1 - 0.014 15.5 1.0 0.036 14.2 0.7 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EPX74147.1 - 0.025 14.8 1.9 0.025 14.8 1.3 2.0 2 0 0 2 2 1 0 C2H2-type zinc finger Methyltransf_15 PF09445.5 EPX74147.1 - 0.039 13.4 0.3 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.13 EPX74147.1 - 0.053 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase PCMT PF01135.14 EPX74147.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) IncA PF04156.9 EPX74147.1 - 0.41 10.2 3.7 0.67 9.5 2.5 1.3 1 0 0 1 1 1 0 IncA protein RRM_5 PF13893.1 EPX74148.1 - 1.3e-11 44.1 0.1 1.3e-11 44.1 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX74148.1 - 3.3e-08 33.0 0.5 7.5e-08 31.8 0.3 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74148.1 - 0.00023 21.0 0.2 0.0007 19.5 0.1 1.9 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EPX74148.1 - 0.00062 19.3 0.1 0.00077 19.0 0.1 1.1 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 EPX74148.1 - 0.0027 17.4 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 Limkain b1 TFIIIC_delta PF12657.2 EPX74149.1 - 1e-22 80.7 2.5 1.8e-21 76.6 0.3 3.3 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EPX74149.1 - 9.1e-20 70.4 6.7 2.2e-19 69.1 4.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Npa1 PF11707.3 EPX74149.1 - 0.017 14.1 0.2 0.017 14.1 0.1 1.9 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal PHF5 PF03660.9 EPX74149.1 - 0.041 13.9 2.3 0.11 12.6 1.6 1.7 1 0 0 1 1 1 0 PHF5-like protein tRNA-synt_1 PF00133.17 EPX74150.1 - 1.9e-221 736.2 0.0 3.2e-221 735.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EPX74150.1 - 1.5e-28 99.4 0.1 3.6e-28 98.2 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EPX74150.1 - 3.6e-18 65.4 1.7 6.5e-06 25.0 0.1 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EPX74150.1 - 0.019 14.0 0.0 0.038 13.1 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Sfi1 PF08457.5 EPX74151.1 - 3.5e-74 250.2 87.1 3.5e-74 250.2 60.4 2.3 1 1 0 2 2 2 2 Sfi1 spindle body protein FinO_N PF12602.3 EPX74151.1 - 3.5 7.9 6.5 3.1 8.1 0.4 3.1 3 0 0 3 3 3 0 Fertility inhibition protein N terminal Histone PF00125.19 EPX74152.1 - 7e-32 109.3 0.1 1.1e-31 108.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EPX74152.1 - 6.2e-06 26.3 0.0 9.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPX74152.1 - 0.0024 17.8 0.2 0.0054 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPX74152.1 - 0.096 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EPX74153.1 - 6.8e-32 109.4 0.1 1.1e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EPX74153.1 - 6.3e-06 26.2 0.0 9.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPX74153.1 - 0.0024 17.8 0.2 0.0056 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPX74153.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EPX74154.1 - 7.2e-15 54.8 0.4 8.7e-15 54.6 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPX74154.1 - 7.1e-06 25.9 0.1 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EPX74154.1 - 5.8e-05 23.1 0.1 8.2e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EPX74154.1 - 8.5e-05 22.4 0.1 0.00012 21.9 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 EPX74154.1 - 0.012 14.8 0.0 0.013 14.8 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EPX74154.1 - 0.029 14.0 0.0 0.037 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated DUF1819 PF08849.6 EPX74154.1 - 0.1 12.0 0.6 0.36 10.2 0.1 1.8 1 1 1 2 2 2 0 Putative inner membrane protein (DUF1819) TFIID_20kDa PF03847.8 EPX74154.1 - 0.1 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A UPF0220 PF05255.6 EPX74155.1 - 4.3e-57 191.9 6.8 4.7e-57 191.8 4.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF1980 PF09323.5 EPX74155.1 - 0.11 12.1 0.6 0.17 11.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF3169 PF11368.3 EPX74155.1 - 3.7 6.6 7.2 2.1 7.5 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Pkinase PF00069.20 EPX74156.1 - 6.1e-64 215.6 0.0 7.1e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74156.1 - 4.7e-27 94.7 0.0 9.4e-27 93.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX74156.1 - 6.6e-07 28.5 0.0 2.5e-06 26.6 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EPX74156.1 - 0.00064 19.5 0.0 0.013 15.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EPX74156.1 - 0.0086 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EPX74156.1 - 0.068 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EPX74156.1 - 0.079 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Porin_3 PF01459.17 EPX74157.1 - 1.2e-78 264.1 0.0 1.4e-78 263.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin CorA PF01544.13 EPX74158.1 - 2e-45 155.0 0.0 3e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein YihI PF04220.7 EPX74158.1 - 0.027 13.8 3.7 0.042 13.1 2.1 1.6 1 1 0 1 1 1 0 Der GTPase activator (YihI) CBP4 PF07960.6 EPX74159.1 - 1.4e-09 37.6 0.0 1.7e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 CBP4 Tom7 PF08038.7 EPX74161.1 - 6e-18 64.0 0.7 6.8e-18 63.8 0.5 1.1 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.22 EPX74162.1 - 3.1e-58 193.4 4.1 1.8e-18 66.0 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF1640 PF07798.6 EPX74164.1 - 2.4e-13 50.5 2.3 3.2e-13 50.1 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Phasin PF05597.6 EPX74164.1 - 0.21 11.3 3.8 2.3 7.9 1.2 2.7 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Phosphodiest PF01663.17 EPX74165.1 - 1.5e-16 60.6 0.2 2.4e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EPX74165.1 - 6.7e-09 35.4 0.8 1.1e-08 34.8 0.5 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EPX74165.1 - 0.00027 20.2 0.0 0.001 18.3 0.0 1.9 1 1 0 1 1 1 1 Sulfatase KIP1 PF07765.7 EPX74165.1 - 0.084 12.7 1.6 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 KIP1-like protein CRT10 PF08728.5 EPX74166.1 - 5.8e-20 70.8 2.6 2.9e-11 42.1 0.3 2.8 2 1 0 2 2 2 2 CRT10 WD40 PF00400.27 EPX74166.1 - 1.1e-07 31.4 3.5 1.8e-07 30.7 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF3402 PF11882.3 EPX74167.1 - 6.1e-61 206.6 10.5 8.9e-61 206.1 7.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EPX74167.1 - 2.3e-35 121.8 1.1 2.3e-35 121.8 0.8 2.3 3 0 0 3 3 3 1 N1221-like protein FA_hydroxylase PF04116.8 EPX74168.1 - 1.8e-11 44.4 22.2 1.8e-11 44.4 15.4 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RPM2 PF08579.6 EPX74169.1 - 0.062 13.4 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF2404 PF10296.4 EPX74170.1 - 0.00078 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) RNase_T PF00929.19 EPX74171.1 - 1.7e-15 57.6 0.0 2.7e-14 53.7 0.0 2.1 1 1 0 1 1 1 1 Exonuclease SAP PF02037.22 EPX74171.1 - 0.00089 18.7 0.5 0.0018 17.7 0.4 1.5 1 0 0 1 1 1 1 SAP domain Tfb4 PF03850.9 EPX74172.1 - 4.1e-99 331.3 1.6 4.8e-99 331.0 1.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 EPX74172.1 - 0.012 15.7 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain CAS_CSE1 PF03378.10 EPX74173.1 - 1.9e-153 510.8 3.3 3.8e-153 509.8 2.3 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EPX74173.1 - 2e-148 493.8 5.9 3.6e-148 493.0 4.1 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EPX74173.1 - 7.4e-16 57.8 0.2 2.8e-15 55.9 0.1 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EPX74173.1 - 0.0033 17.3 0.7 0.046 13.6 0.0 3.2 3 1 0 3 3 3 1 Exportin 1-like protein GIDA PF01134.17 EPX74174.1 - 1.4e-143 478.5 0.0 1.7e-143 478.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EPX74174.1 - 1.2e-13 50.9 0.0 2.8e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EPX74174.1 - 4e-06 26.8 0.4 1.1e-05 25.3 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPX74174.1 - 1.2e-05 24.6 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EPX74174.1 - 0.001 18.0 2.1 0.63 8.8 0.5 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPX74174.1 - 0.0011 19.3 0.1 0.0028 18.0 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPX74174.1 - 0.004 16.0 2.5 0.0066 15.3 1.0 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 EPX74174.1 - 0.0079 15.7 0.2 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EPX74174.1 - 0.028 13.3 0.2 0.08 11.8 0.2 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EPX74174.1 - 0.036 13.8 0.8 0.084 12.6 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPX74174.1 - 0.059 12.2 0.0 0.21 10.4 0.0 1.8 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EPX74174.1 - 0.13 12.3 0.1 0.51 10.3 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPX74174.1 - 0.23 10.4 0.5 0.37 9.7 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EPX74174.1 - 0.72 8.2 3.5 0.6 8.5 0.5 2.2 3 0 0 3 3 3 0 HI0933-like protein ARID PF01388.16 EPX74175.1 - 2.5e-19 68.9 0.0 6.4e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain LIM_bind PF01803.11 EPX74176.1 - 6.8e-59 198.8 0.1 6.8e-59 198.8 0.0 1.5 2 0 0 2 2 2 1 LIM-domain binding protein R3H PF01424.17 EPX74177.1 - 2.8e-12 46.1 0.0 7.8e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EPX74177.1 - 5.4e-07 29.3 0.3 1e-06 28.4 0.2 1.5 1 0 0 1 1 1 1 G-patch domain DUF3654 PF12376.3 EPX74177.1 - 0.00083 19.1 2.9 0.18 11.6 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3654) WSC PF01822.14 EPX74178.1 - 1.2e-09 37.9 8.4 1.2e-09 37.9 5.8 2.9 2 1 0 2 2 2 1 WSC domain TMEM154 PF15102.1 EPX74178.1 - 2.5e-05 24.0 0.0 2.5e-05 24.0 0.0 2.2 1 1 1 2 2 2 1 TMEM154 protein family SKG6 PF08693.5 EPX74178.1 - 3e-05 23.2 0.5 3e-05 23.2 0.3 2.5 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF605 PF04652.11 EPX74178.1 - 0.00054 19.4 11.6 0.00068 19.1 8.1 1.1 1 0 0 1 1 1 1 Vta1 like Mid2 PF04478.7 EPX74178.1 - 0.0017 17.7 0.5 0.0017 17.7 0.4 2.2 1 1 0 2 2 2 1 Mid2 like cell wall stress sensor Podoplanin PF05808.6 EPX74178.1 - 0.01 15.4 4.3 0.02 14.4 2.9 1.4 1 0 0 1 1 1 0 Podoplanin Adeno_E3_CR2 PF02439.10 EPX74178.1 - 0.054 13.0 6.1 0.099 12.2 4.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF230 PF03003.11 EPX74178.1 - 0.059 12.8 1.4 0.14 11.6 0.6 1.9 2 0 0 2 2 2 0 Poxvirus proteins of unknown function DUF347 PF03988.7 EPX74178.1 - 0.14 12.0 0.5 0.32 10.9 0.3 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Thioredoxin PF00085.15 EPX74180.1 - 1.5e-29 101.7 0.9 1.4e-17 63.2 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 EPX74180.1 - 1.6e-15 57.4 7.6 5.3e-08 32.8 0.0 4.3 2 1 2 4 4 4 4 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EPX74180.1 - 8.8e-07 29.1 4.7 0.025 14.7 0.0 4.9 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EPX74180.1 - 5.4e-06 26.1 0.0 0.33 10.8 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_8 PF13905.1 EPX74180.1 - 9.4e-06 25.6 6.8 0.29 11.2 0.1 4.4 3 2 2 5 5 5 3 Thioredoxin-like HyaE PF07449.6 EPX74180.1 - 0.0003 20.6 0.0 0.16 11.8 0.0 3.1 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE WD40 PF00400.27 EPX74181.1 - 1.8e-69 227.3 25.1 1.5e-08 34.1 0.0 11.9 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 EPX74181.1 - 1.5e-18 66.6 0.1 2.5e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EPX74181.1 - 3.4e-05 22.1 1.7 0.7 7.9 0.0 4.9 4 1 0 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPX74181.1 - 0.00012 20.9 0.3 6 5.4 0.0 4.7 2 2 1 3 3 3 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 EPX74181.1 - 0.03 13.1 0.8 0.26 10.0 0.0 2.4 3 0 0 3 3 3 0 Coatomer WD associated region Nbas_N PF15492.1 EPX74181.1 - 0.034 13.2 0.0 1.6 7.7 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal zf-C3HC4_3 PF13920.1 EPX74182.1 - 5.8e-11 41.8 6.3 9.2e-11 41.2 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPX74182.1 - 6.6e-11 41.8 6.7 6.6e-11 41.8 4.7 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EPX74182.1 - 9.3e-10 38.0 7.9 1.9e-09 37.0 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPX74182.1 - 9.5e-09 35.1 8.2 9.5e-09 35.1 5.7 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX74182.1 - 3.2e-08 33.1 7.4 5.6e-08 32.3 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPX74182.1 - 0.00014 21.5 1.4 0.00023 20.9 1.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EPX74182.1 - 0.00066 19.5 9.2 0.0013 18.5 6.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EPX74182.1 - 0.0035 16.8 4.9 0.0068 15.9 3.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EPX74182.1 - 0.017 14.8 2.9 0.017 14.8 2.0 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 EPX74182.1 - 0.021 14.3 2.2 0.043 13.3 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EPX74182.1 - 0.037 13.8 4.8 0.068 12.9 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EPX74182.1 - 0.037 14.1 4.7 0.1 12.6 3.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger Baculo_IE-1 PF05290.6 EPX74182.1 - 0.038 13.7 2.3 0.057 13.1 1.6 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 EPX74182.1 - 0.32 10.5 6.8 4 7.0 4.7 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.2 EPX74182.1 - 0.36 10.6 6.2 0.68 9.7 4.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon Exo_endo_phos PF03372.18 EPX74183.1 - 4.8e-19 69.2 0.0 7.1e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EPX74183.1 - 5.1e-13 48.6 0.2 1.5e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EPX74183.1 - 0.00064 19.5 8.5 0.0013 18.6 2.5 3.1 2 1 0 2 2 2 1 GRF zinc finger CBFD_NFYB_HMF PF00808.18 EPX74184.1 - 6.5e-11 42.1 0.1 1.2e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPX74184.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PUA PF01472.15 EPX74184.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 PUA domain LSM PF01423.17 EPX74185.1 - 2.6e-14 52.5 1.0 3.7e-14 51.9 0.7 1.2 1 0 0 1 1 1 1 LSM domain PIGA PF08288.7 EPX74186.1 - 6e-44 148.3 3.3 6.1e-44 148.3 0.9 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EPX74186.1 - 2.1e-31 108.6 0.0 3.1e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPX74186.1 - 1.1e-14 54.7 0.0 1.9e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EPX74186.1 - 2.5e-14 53.3 0.2 4.8e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EPX74186.1 - 3.8e-12 46.6 0.0 6.1e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EPX74186.1 - 0.00062 19.6 1.4 0.0088 15.8 0.2 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EPX74186.1 - 0.0054 16.9 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 NTP_transf_2 PF01909.18 EPX74186.1 - 0.096 13.0 0.1 4.1 7.7 0.0 2.7 2 0 0 2 2 2 0 Nucleotidyltransferase domain Pribosyl_synth PF14572.1 EPX74187.1 - 4.3e-39 134.1 1.5 4.5e-34 117.8 0.8 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EPX74187.1 - 5e-32 110.0 0.0 3e-31 107.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EPX74187.1 - 9.3e-11 41.5 0.1 2e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPX74187.1 - 0.0066 15.6 0.1 0.012 14.8 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CTP_transf_1 PF01148.15 EPX74188.1 - 1.6e-22 80.4 6.1 1.1e-18 67.7 2.9 2.0 1 1 1 2 2 2 2 Cytidylyltransferase family DUF1673 PF07895.6 EPX74188.1 - 0.0025 17.3 0.5 0.0031 17.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) DUF606 PF04657.8 EPX74188.1 - 0.061 13.4 2.4 1.1 9.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF606 Transgly_assoc PF04226.8 EPX74188.1 - 5.1 7.2 7.8 40 4.3 3.6 3.2 3 1 0 3 3 3 0 Transglycosylase associated protein MAD PF05557.8 EPX74189.1 - 5.8e-113 378.4 74.1 6.7e-113 378.2 51.3 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Spc7 PF08317.6 EPX74189.1 - 0.00056 18.6 12.7 0.00056 18.6 8.8 5.1 2 2 3 5 5 5 1 Spc7 kinetochore protein TraH PF06122.6 EPX74189.1 - 0.038 12.8 7.3 0.073 11.8 5.1 1.4 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein DUF1647 PF07801.6 EPX74189.1 - 2.5 7.5 7.2 0.99 8.8 2.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1647) FTHFS PF01268.14 EPX74189.1 - 4.8 5.0 6.3 0.44 8.4 0.3 2.0 2 1 0 2 2 2 0 Formate--tetrahydrofolate ligase Ribosomal_S25 PF03297.10 EPX74190.1 - 1.8e-33 114.6 0.5 2e-33 114.5 0.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Lactamase_B_2 PF12706.2 EPX74191.1 - 1.6e-32 112.6 0.0 2.6e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPX74191.1 - 1.7e-09 37.5 0.0 3.2e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EPX74191.1 - 5.5e-08 32.1 0.0 2.1e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 tRNase Z endonuclease But2 PF09792.4 EPX74192.1 - 1.4e-33 115.6 0.9 2.3e-33 114.9 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Reticulon PF02453.12 EPX74193.1 - 2e-31 108.8 4.7 3e-31 108.2 3.3 1.2 1 0 0 1 1 1 1 Reticulon Patched PF02460.13 EPX74193.1 - 0.0071 14.3 0.3 0.011 13.7 0.2 1.2 1 0 0 1 1 1 1 Patched family DUF605 PF04652.11 EPX74193.1 - 9.7 5.4 16.9 14 4.9 11.7 1.2 1 0 0 1 1 1 0 Vta1 like Adap_comp_sub PF00928.16 EPX74195.1 - 5.3e-49 166.6 0.7 1.2e-48 165.5 0.1 1.7 2 0 0 2 2 2 1 Adaptor complexes medium subunit family DUF3857 PF12969.2 EPX74195.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) H_lectin PF09458.5 EPX74195.1 - 0.086 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 H-type lectin domain Nse5 PF08691.5 EPX74196.1 - 0.00018 20.1 0.0 0.00034 19.2 0.0 1.4 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Plus-3 PF03126.13 EPX74197.1 - 3.7e-34 117.0 0.0 1.1e-33 115.5 0.0 1.9 1 0 0 1 1 1 1 Plus-3 domain RNA_pol_Rpb1_1 PF04997.7 EPX74198.1 - 7.1e-98 327.9 0.0 1.1e-97 327.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EPX74198.1 - 3.9e-96 321.5 0.5 7.4e-96 320.6 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EPX74198.1 - 1.3e-67 226.9 0.0 2.5e-67 225.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EPX74198.1 - 1.6e-40 138.4 0.0 3.1e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EPX74198.1 - 2.6e-32 110.7 0.0 6.7e-32 109.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 EPX74198.1 - 0.011 15.2 0.1 0.03 13.8 0.0 1.7 1 0 0 1 1 1 0 InsA N-terminal domain EAP30 PF04157.11 EPX74200.1 - 6.3e-48 162.8 0.0 7.2e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DUF4279 PF14106.1 EPX74200.1 - 0.0039 17.0 0.2 0.015 15.1 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4279) GvpK PF05121.7 EPX74200.1 - 0.13 12.0 0.1 0.37 10.6 0.1 1.7 2 0 0 2 2 2 0 Gas vesicle protein K Filament PF00038.16 EPX74201.1 - 0.019 14.4 2.5 0.78 9.1 0.1 2.1 2 0 0 2 2 2 0 Intermediate filament protein Seryl_tRNA_N PF02403.17 EPX74201.1 - 0.024 14.6 4.6 0.13 12.3 0.2 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 EPX74201.1 - 0.055 12.4 6.3 0.35 9.7 0.2 2.0 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EPX74201.1 - 0.058 12.9 2.3 3.9 7.0 0.1 2.1 2 0 0 2 2 2 0 IncA protein PilO PF04350.8 EPX74201.1 - 0.12 12.2 1.5 0.95 9.3 0.0 2.1 2 0 0 2 2 2 0 Pilus assembly protein, PilO DUF3573 PF12097.3 EPX74201.1 - 0.16 10.5 3.6 1.7 7.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Herpes_capsid PF06112.6 EPX74201.1 - 0.16 11.9 3.7 0.32 11.0 2.6 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein HrpB7 PF09486.5 EPX74201.1 - 0.23 11.3 1.5 6.7 6.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DivIC PF04977.10 EPX74201.1 - 0.69 9.4 5.1 11 5.5 0.5 2.5 2 0 0 2 2 2 0 Septum formation initiator CENP-Q PF13094.1 EPX74201.1 - 5.5 6.9 9.0 5.7 6.9 1.1 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit LEF-9 PF05094.7 EPX74202.1 - 0.06 11.7 0.0 0.08 11.3 0.0 1.1 1 0 0 1 1 1 0 Late expression factor 9 (LEF-9) RabGAP-TBC PF00566.13 EPX74203.1 - 2.3e-28 99.1 4.3 3.3e-28 98.6 3.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4212 PF13937.1 EPX74203.1 - 0.017 15.1 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) CN_hydrolase PF00795.17 EPX74204.1 - 8.6e-25 87.1 0.0 2.9e-24 85.4 0.0 1.7 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase NOGCT PF08155.6 EPX74205.1 - 2.6e-27 94.2 0.1 5.8e-27 93.1 0.1 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EPX74205.1 - 1.6e-26 91.9 0.2 3e-26 91.0 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EPX74205.1 - 2.9e-16 59.4 0.0 6.4e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPX74205.1 - 5.2e-09 35.5 0.1 1e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPX74205.1 - 0.0025 17.6 0.0 2.3 8.0 0.0 2.8 1 1 1 2 2 2 2 Dynamin family DUF3591 PF12157.3 EPX74205.1 - 0.009 14.4 0.6 0.014 13.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) AIG1 PF04548.11 EPX74205.1 - 0.013 14.6 1.9 0.014 14.4 0.0 2.1 3 0 0 3 3 3 0 AIG1 family Miro PF08477.8 EPX74205.1 - 0.014 15.8 0.1 0.06 13.8 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EPX74205.1 - 0.025 13.7 0.0 0.23 10.6 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPX74205.1 - 0.053 13.6 1.7 2.7 8.1 0.0 3.1 3 1 0 3 3 3 0 AAA domain RNA_pol_I_TF PF04090.7 EPX74206.1 - 9.4e-38 129.4 0.1 1.2e-37 129.0 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor TPR_6 PF13174.1 EPX74206.1 - 0.055 13.9 0.6 2.9 8.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPX74206.1 - 0.17 12.6 2.5 7 7.4 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.2 EPX74207.1 - 4.5e-14 52.5 2.2 1.6e-08 34.7 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPX74207.1 - 1.7e-12 47.4 3.1 8.4e-05 22.9 0.0 4.5 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 EPX74207.1 - 2.8e-10 39.4 2.8 1.9e-06 27.3 0.3 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EPX74207.1 - 1.2e-08 34.9 3.5 0.0038 17.4 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPX74207.1 - 2e-08 33.6 3.2 0.00022 21.1 0.1 4.7 5 0 0 5 5 5 1 Ankyrin repeat KilA-N PF04383.8 EPX74207.1 - 8.6e-06 25.3 0.1 6.6e-05 22.5 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain Pribosyltran PF00156.22 EPX74208.1 - 1.5e-13 50.5 0.0 2.4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPX74208.1 - 0.018 14.2 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF619 PF04768.8 EPX74209.1 - 2.7e-51 173.3 0.1 5.2e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Sld5 PF05916.6 EPX74210.1 - 3.1e-21 75.7 1.7 5.4e-21 74.9 1.1 1.4 1 0 0 1 1 1 1 GINS complex protein Lant_dehyd_C PF04738.8 EPX74210.1 - 0.015 13.5 0.2 0.02 13.1 0.1 1.1 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus Nbl1_Borealin_N PF10444.4 EPX74211.1 - 6e-19 67.1 0.9 1.2e-18 66.1 0.6 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal CBFB_NFYA PF02045.10 EPX74212.1 - 9.2e-29 99.7 5.8 1.6e-28 98.9 4.0 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TspO_MBR PF03073.10 EPX74213.1 - 2e-36 124.7 11.2 2.3e-36 124.5 7.8 1.1 1 0 0 1 1 1 1 TspO/MBR family BAR PF03114.13 EPX74214.1 - 2.5e-58 197.2 0.5 3.2e-58 196.9 0.3 1.1 1 0 0 1 1 1 1 BAR domain DUF445 PF04286.7 EPX74214.1 - 0.051 13.1 0.1 0.081 12.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) ARS2 PF04959.8 EPX74215.1 - 8.6e-09 35.9 0.3 2e-08 34.6 0.1 1.7 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF3546 PF12066.3 EPX74215.1 - 3.5e-07 30.1 2.8 1e-06 28.6 1.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) TPR_11 PF13414.1 EPX74216.1 - 5.3e-16 58.0 3.7 4.3e-09 35.9 0.0 4.5 2 2 2 4 4 4 3 TPR repeat TPR_2 PF07719.12 EPX74216.1 - 2.6e-13 48.7 3.7 0.00062 19.4 0.0 5.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPX74216.1 - 3.7e-11 42.1 3.2 0.0022 17.5 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPX74216.1 - 7.9e-10 38.1 0.7 0.11 12.7 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPX74216.1 - 2.1e-08 34.0 0.1 2.4 9.0 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPX74216.1 - 1.8e-06 28.1 3.2 0.32 11.3 0.0 4.9 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPX74216.1 - 2.4e-06 27.3 0.1 0.09 12.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EPX74216.1 - 6.4e-06 26.2 3.9 0.023 14.8 0.7 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EPX74216.1 - 1.3e-05 25.0 3.7 0.22 11.5 0.1 4.4 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPX74216.1 - 2e-05 25.0 0.1 0.62 10.8 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 EPX74216.1 - 0.0066 16.5 0.1 6.4 6.9 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPX74216.1 - 0.0067 16.1 6.0 0.25 11.2 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPX74216.1 - 0.014 15.1 0.4 30 4.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPX74216.1 - 0.14 12.6 1.2 1.8 9.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 EPX74217.1 - 7.5e-53 179.3 0.0 4e-32 111.3 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74217.1 - 3.2e-21 75.5 0.0 1.1e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EPX74217.1 - 0.007 16.1 0.0 0.045 13.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPX74217.1 - 0.038 12.9 0.0 2.2 7.1 0.0 2.5 3 0 0 3 3 3 0 Kinase-like TPP_enzyme_N PF02776.13 EPX74218.1 - 4.5e-46 156.4 0.1 1.7e-45 154.6 0.1 1.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPX74218.1 - 5.6e-32 110.3 0.0 1.2e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EPX74218.1 - 1.4e-23 83.2 0.0 2.8e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain zinc-ribbons_6 PF07191.7 EPX74218.1 - 0.082 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbons Phosphodiest PF01663.17 EPX74219.1 - 2.6e-88 296.8 1.8 3.1e-88 296.5 1.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EPX74219.1 - 1e-07 31.4 0.2 0.00052 19.3 0.0 2.3 2 0 0 2 2 2 2 Sulfatase YL1_C PF08265.6 EPX74219.1 - 0.11 12.1 0.6 6.8 6.3 0.1 2.7 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Pyridox_oxase_2 PF12766.2 EPX74220.1 - 2.6e-20 72.6 0.0 4e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Hpt PF01627.18 EPX74221.1 - 1e-12 47.8 0.0 1.9e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Hpt domain Aminotran_1_2 PF00155.16 EPX74222.1 - 8.4e-84 281.5 0.0 9.6e-84 281.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II KH_1 PF00013.24 EPX74223.1 - 9.6e-39 130.8 2.5 9.2e-13 47.6 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EPX74223.1 - 8e-29 98.7 4.1 2.1e-08 33.5 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EPX74223.1 - 2e-12 46.4 0.1 0.00036 20.0 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EPX74223.1 - 1.1e-06 28.2 0.2 0.41 10.3 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EPX74223.1 - 3.7e-06 26.6 1.7 5.7 6.8 0.0 4.5 5 0 0 5 5 5 4 NusA-like KH domain AAA PF00004.24 EPX74224.1 - 1.3e-41 141.9 0.0 2.3e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EPX74224.1 - 8.6e-07 29.0 0.0 2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EPX74224.1 - 9.2e-07 29.0 0.4 0.00022 21.3 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPX74224.1 - 1e-06 28.5 0.1 3.8e-06 26.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EPX74224.1 - 1.2e-05 24.4 0.0 1.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EPX74224.1 - 6.8e-05 22.9 0.2 0.00027 20.9 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EPX74224.1 - 0.00018 20.6 0.0 0.00035 19.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EPX74224.1 - 0.00059 19.8 1.3 0.0017 18.3 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 EPX74224.1 - 0.00096 19.0 0.0 0.003 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPX74224.1 - 0.0017 19.1 0.5 0.0081 16.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EPX74224.1 - 0.0023 17.1 0.8 0.4 9.7 0.1 2.6 2 1 1 3 3 3 1 KaiC AAA_25 PF13481.1 EPX74224.1 - 0.0031 16.9 1.0 0.2 11.0 0.3 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EPX74224.1 - 0.0047 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EPX74224.1 - 0.0056 16.5 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPX74224.1 - 0.0063 16.2 0.3 0.014 15.1 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 EPX74224.1 - 0.0075 15.7 0.1 0.74 9.2 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 EPX74224.1 - 0.015 14.9 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EPX74224.1 - 0.017 15.4 0.5 0.04 14.2 0.0 1.9 2 1 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 EPX74224.1 - 0.017 14.2 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 EPX74224.1 - 0.022 14.9 0.0 0.077 13.1 0.0 2.0 2 0 0 2 2 1 0 RNA helicase NB-ARC PF00931.17 EPX74224.1 - 0.03 13.2 0.0 0.056 12.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.8 EPX74224.1 - 0.034 12.8 0.0 0.07 11.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EPX74224.1 - 0.049 12.7 0.0 0.096 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EPX74224.1 - 0.055 13.1 0.7 0.33 10.6 0.1 2.4 2 1 0 3 3 3 0 NACHT domain AAA_24 PF13479.1 EPX74224.1 - 0.056 13.0 0.2 0.14 11.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EPX74224.1 - 0.095 11.6 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 EPX74224.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 EPX74224.1 - 0.15 11.6 0.4 0.3 10.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain His_Phos_2 PF00328.17 EPX74225.1 - 2e-35 122.7 0.0 2.7e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-UBR PF02207.15 EPX74226.1 - 1.5e-14 53.4 13.4 1.5e-14 53.4 9.3 3.7 3 1 1 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 EPX74226.1 - 4.1e-05 23.1 6.8 4.1e-05 23.1 4.7 4.0 3 1 1 4 4 4 1 PHD-finger DUF692 PF05114.8 EPX74226.1 - 0.018 13.9 0.8 0.071 12.0 0.1 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF692) Novirhabdo_Nv PF05554.6 EPX74226.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral hemorrhagic septicemia virus non-virion protein DUF1178 PF06676.6 EPX74226.1 - 0.18 12.0 4.7 5.2 7.2 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) MCM PF00493.18 EPX74227.1 - 2.3e-139 463.8 0.1 3e-139 463.4 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EPX74227.1 - 3.9e-33 114.6 22.9 3.9e-33 114.6 15.8 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EPX74227.1 - 2.5e-18 66.7 0.0 7e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPX74227.1 - 5.8e-09 35.4 0.0 2.1e-07 30.3 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPX74227.1 - 1e-06 28.5 0.0 2.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPX74227.1 - 0.00017 21.2 0.1 0.0008 19.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPX74227.1 - 0.0018 17.7 0.1 0.0089 15.5 0.1 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 EPX74227.1 - 0.016 15.3 0.0 0.049 13.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sec23_trunk PF04811.10 EPX74228.1 - 1e-64 218.1 0.0 1.5e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPX74228.1 - 1.7e-18 65.9 0.2 3.1e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPX74228.1 - 9.5e-18 64.5 0.0 2.2e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EPX74228.1 - 2e-15 56.0 2.0 2e-15 56.0 1.4 1.7 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EPX74228.1 - 1.2e-08 34.5 0.0 3.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF2410 PF10307.4 EPX74229.1 - 4.4e-65 218.7 0.6 5.8e-65 218.3 0.4 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Fig1 PF12351.3 EPX74230.1 - 3.8e-12 46.4 18.9 1.1e-11 44.9 9.1 2.5 1 1 1 2 2 2 2 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EPX74230.1 - 1.7 8.1 18.3 5.7 6.4 12.7 1.8 1 1 0 1 1 1 0 SUR7/PalI family WD40 PF00400.27 EPX74231.1 - 4e-20 70.8 27.5 9.8e-10 37.9 0.0 10.2 10 0 0 10 10 10 5 WD domain, G-beta repeat PuR_N PF09182.5 EPX74231.1 - 0.16 11.6 0.0 0.66 9.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal GTP_EFTU PF00009.22 EPX74232.1 - 6.2e-58 195.3 0.3 6.2e-58 195.3 0.2 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EPX74232.1 - 1e-31 108.9 0.0 2.4e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EPX74232.1 - 6.5e-31 106.0 0.0 1.5e-30 104.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EPX74232.1 - 9.1e-23 79.9 0.0 2.6e-22 78.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPX74232.1 - 2.2e-10 40.4 0.1 5.5e-10 39.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Sec66 PF09802.4 EPX74233.1 - 7.9e-42 142.7 0.1 9.3e-42 142.5 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SHR3_chaperone PF08229.6 EPX74234.1 - 9.4e-45 151.9 5.9 1.2e-44 151.6 4.1 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Tom37_C PF11801.3 EPX74235.1 - 3.7e-15 56.2 0.4 3.7e-15 56.2 0.3 2.4 2 0 0 2 2 2 1 Tom37 C-terminal domain Tom37 PF10568.4 EPX74235.1 - 2.2e-14 53.4 0.0 4.4e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EPX74235.1 - 1.9e-05 24.4 0.0 4.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPX74235.1 - 4e-05 24.0 0.0 7.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PAP2 PF01569.16 EPX74236.1 - 8.1e-26 90.2 1.6 1.3e-25 89.5 1.1 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EPX74236.1 - 0.0025 17.3 0.5 0.0041 16.6 0.3 1.5 1 1 0 1 1 1 1 PAP2 superfamily YhhN PF07947.9 EPX74236.1 - 0.017 14.4 0.9 0.017 14.4 0.6 1.8 2 1 0 2 2 2 0 YhhN-like protein DUF2955 PF11168.3 EPX74236.1 - 0.078 12.6 0.1 0.078 12.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2955) DUF2069 PF09842.4 EPX74236.1 - 0.42 10.5 4.2 0.44 10.5 0.1 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2069) DUF1769 PF08588.5 EPX74237.1 - 4.8e-22 77.6 0.4 8e-22 76.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Saw1 PF11561.3 EPX74238.1 - 1.8e-05 24.2 2.9 0.11 11.8 0.1 3.0 1 1 2 3 3 3 3 Single strand annealing-weakened 1 WGG PF10273.4 EPX74239.1 - 8.9e-24 83.3 0.0 2.1e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Dehalogenase PF13486.1 EPX74239.1 - 0.012 15.0 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit RRP7 PF12923.2 EPX74239.1 - 0.023 14.7 2.1 0.15 12.0 0.1 2.1 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Ribosomal_S17 PF00366.15 EPX74240.1 - 6.5e-14 51.7 1.4 7.7e-14 51.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 DMRL_synthase PF00885.14 EPX74241.1 - 2.8e-44 150.2 0.0 3.3e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF1749 PF08538.5 EPX74242.1 - 0.072 11.9 0.1 0.073 11.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Stn1 PF10451.4 EPX74243.1 - 6.5e-23 80.8 0.4 9.7e-23 80.3 0.3 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Stn1_C PF12659.2 EPX74243.1 - 2e-05 24.3 1.1 2.6e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Telomere capping C-terminal wHTH tRNA_anti-codon PF01336.20 EPX74243.1 - 0.027 14.3 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Phage_Treg PF04761.7 EPX74243.1 - 0.069 12.9 0.1 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Lactococcus bacteriophage putative transcription regulator SAICAR_synt PF01259.13 EPX74245.1 - 4.1e-92 307.7 0.0 4.8e-92 307.5 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase MIS13 PF08202.6 EPX74246.1 - 5.3e-58 196.4 10.0 7.6e-58 195.9 6.9 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family RE_NgoFVII PF09565.5 EPX74246.1 - 0.064 12.2 0.9 0.23 10.3 0.1 1.9 2 0 0 2 2 2 0 NgoFVII restriction endonuclease BLOC1_2 PF10046.4 EPX74246.1 - 0.1 12.7 1.8 0.17 12.0 0.1 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.6 EPX74246.1 - 6.5 7.2 7.3 0.45 10.9 0.1 2.7 3 1 0 3 3 3 0 Syntaxin 6, N-terminal MFS_1 PF07690.11 EPX74247.1 - 1.4e-34 119.4 31.3 1.4e-34 119.4 21.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX74247.1 - 2e-07 30.0 31.6 6.5e-07 28.2 21.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3464 PF11947.3 EPX74247.1 - 0.5 9.8 4.0 7.5 6.0 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3464) Pkinase PF00069.20 EPX74249.1 - 3.7e-55 186.8 0.0 4.7e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74249.1 - 1.6e-37 128.9 0.0 2.2e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX74249.1 - 4e-06 26.0 0.0 1.2e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EPX74249.1 - 0.0079 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EPX74249.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPX74249.1 - 0.21 10.3 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PPP4R2 PF09184.6 EPX74249.1 - 9.1 5.7 7.9 16 4.9 5.5 1.3 1 0 0 1 1 1 0 PPP4R2 Peptidase_C12 PF01088.16 EPX74250.1 - 5e-68 228.4 0.0 8.2e-68 227.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Skp1 PF01466.14 EPX74251.1 - 2.4e-38 129.9 0.4 5.2e-38 128.9 0.3 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EPX74251.1 - 8.9e-26 89.7 0.2 2e-25 88.6 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EPX74251.1 - 0.07 13.1 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) DUF4160 PF13711.1 EPX74251.1 - 0.089 12.6 0.0 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) Mis12 PF05859.7 EPX74252.1 - 9.8e-35 119.4 0.3 9.8e-35 119.4 0.2 1.4 2 0 0 2 2 2 1 Mis12 protein Effector_1 PF04518.7 EPX74252.1 - 0.005 15.8 0.9 0.0073 15.3 0.6 1.2 1 0 0 1 1 1 1 Effector from type III secretion system TcdA_TcdB PF12919.2 EPX74252.1 - 0.018 13.5 1.9 0.02 13.4 0.8 1.4 1 1 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Prefoldin PF02996.12 EPX74252.1 - 0.032 13.8 0.1 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 Prefoldin subunit Swi5 PF07061.6 EPX74253.1 - 6.6e-25 86.7 1.5 7e-25 86.6 1.0 1.0 1 0 0 1 1 1 1 Swi5 Mei5 PF10376.4 EPX74253.1 - 0.0011 18.5 0.8 0.0012 18.3 0.5 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein YlqD PF11068.3 EPX74253.1 - 0.0046 17.0 3.2 0.0048 16.9 2.2 1.1 1 0 0 1 1 1 1 YlqD protein Tropomyosin_1 PF12718.2 EPX74253.1 - 0.005 16.6 1.4 0.0061 16.4 0.9 1.2 1 0 0 1 1 1 1 Tropomyosin like KNOX2 PF03791.8 EPX74253.1 - 0.016 14.5 0.4 0.033 13.4 0.3 1.5 1 0 0 1 1 1 0 KNOX2 domain TipAS PF07739.8 EPX74253.1 - 0.017 15.4 0.2 0.018 15.3 0.2 1.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain ORF11CD3 PF10549.4 EPX74253.1 - 0.04 13.6 2.3 0.074 12.7 1.0 2.0 2 1 1 3 3 2 0 ORF11CD3 domain IncA PF04156.9 EPX74253.1 - 0.049 13.2 2.2 0.048 13.2 1.5 1.2 1 0 0 1 1 1 0 IncA protein Prefoldin_2 PF01920.15 EPX74253.1 - 0.053 13.2 4.8 0.086 12.6 3.3 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF1619 PF07773.6 EPX74253.1 - 0.071 12.9 0.2 0.075 12.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1619) DUF3584 PF12128.3 EPX74253.1 - 0.11 9.8 3.1 0.11 9.8 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4164 PF13747.1 EPX74253.1 - 0.16 12.1 2.6 0.23 11.6 1.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Cortex-I_coil PF09304.5 EPX74253.1 - 0.18 11.8 5.2 0.2 11.7 3.1 1.5 1 1 0 1 1 1 0 Cortexillin I, coiled coil Ribosomal_L29 PF00831.18 EPX74253.1 - 0.22 11.2 2.6 0.32 10.7 1.8 1.3 1 0 0 1 1 1 0 Ribosomal L29 protein DUF2681 PF10883.3 EPX74253.1 - 0.33 11.1 4.3 0.45 10.7 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) bZIP_1 PF00170.16 EPX74253.1 - 0.36 10.8 4.4 0.56 10.2 3.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF4600 PF15372.1 EPX74253.1 - 0.4 10.8 4.8 0.6 10.3 3.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) HrpB7 PF09486.5 EPX74253.1 - 0.5 10.2 2.9 1.4 8.8 1.7 1.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) M PF02370.11 EPX74253.1 - 0.56 10.7 10.1 0.81 10.2 4.1 2.6 1 1 1 2 2 2 0 M protein repeat Med4 PF10018.4 EPX74253.1 - 0.57 9.5 4.7 0.6 9.4 2.4 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 bZIP_2 PF07716.10 EPX74253.1 - 1 9.2 6.8 1.7 8.5 4.7 1.5 1 0 0 1 1 1 0 Basic region leucine zipper HNOBA PF07701.9 EPX74253.1 - 2.5 7.2 5.3 2.6 7.2 3.4 1.3 1 1 0 1 1 1 0 Heme NO binding associated IF4E PF01652.13 EPX74254.1 - 4.2e-54 182.5 0.3 5.1e-54 182.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Herpes_UL49_2 PF04823.7 EPX74254.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Nfu_N PF08712.6 EPX74255.1 - 1.6e-30 104.5 0.0 3.3e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EPX74255.1 - 8.4e-22 76.7 0.0 1.2e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain Mur_ligase_M PF08245.7 EPX74256.1 - 5e-06 26.6 0.3 0.00038 20.5 0.2 3.3 2 1 0 2 2 2 1 Mur ligase middle domain peroxidase PF00141.18 EPX74256.1 - 0.037 13.5 0.0 8.4 5.7 0.0 3.0 2 1 1 3 3 3 0 Peroxidase CPSF100_C PF13299.1 EPX74257.1 - 1.1e-34 119.9 0.0 2.3e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EPX74257.1 - 3.3e-24 85.2 0.0 7.1e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EPX74257.1 - 1.4e-06 27.9 0.0 3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EPX74257.1 - 0.00011 21.8 0.2 0.00025 20.6 0.1 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPX74257.1 - 0.0014 18.3 0.1 0.0036 17.0 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPX74257.1 - 0.05 13.2 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Transglut_core PF01841.14 EPX74258.1 - 1e-13 51.5 1.3 2.1e-13 50.4 0.9 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 EPX74258.1 - 9.6e-12 44.5 0.6 1.7e-11 43.7 0.4 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain PhnA_Zn_Ribbon PF08274.7 EPX74258.1 - 0.0017 18.0 3.0 0.0043 16.7 2.1 1.6 1 0 0 1 1 1 1 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.2 EPX74258.1 - 0.0023 17.7 2.2 0.0095 15.7 1.5 2.1 1 0 0 1 1 1 1 Transposase zinc-ribbon domain SET PF00856.23 EPX74259.1 - 7.3e-05 23.1 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 SET domain Drf_GBD PF06371.8 EPX74260.1 - 1.9e-18 66.5 3.3 3.8e-18 65.5 2.1 1.6 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain ING PF12998.2 EPX74261.1 - 2.2e-14 53.6 0.4 4.5e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EPX74261.1 - 2.8e-09 36.5 8.2 6.5e-09 35.3 5.7 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EPX74261.1 - 0.00014 21.9 0.2 0.00046 20.2 0.1 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain DegQ PF08181.6 EPX74261.1 - 0.037 13.7 0.1 0.48 10.1 0.1 2.4 1 1 0 1 1 1 0 DegQ (SacQ) family Innate_immun PF12782.2 EPX74261.1 - 1.1 8.4 18.9 1.5 7.9 13.1 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family RRF PF01765.14 EPX74262.1 - 8.9e-24 83.8 15.1 1.2e-22 80.1 5.4 2.1 2 0 0 2 2 2 2 Ribosome recycling factor RRM_DME PF15628.1 EPX74262.1 - 0.003 17.2 0.1 0.43 10.3 0.0 2.5 2 0 0 2 2 2 1 RRM in Demeter DUF3437 PF11919.3 EPX74262.1 - 0.041 13.6 0.3 0.15 11.7 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) FMN_red PF03358.10 EPX74262.1 - 0.13 11.7 0.6 8.9 5.8 0.0 2.2 1 1 0 2 2 2 0 NADPH-dependent FMN reductase CRISPR_Cas2 PF09827.4 EPX74262.1 - 0.14 12.3 4.4 4.9 7.3 0.1 3.1 3 0 0 3 3 3 0 CRISPR associated protein Cas2 YlqD PF11068.3 EPX74262.1 - 0.29 11.1 8.6 0.12 12.3 1.2 2.3 2 0 0 2 2 2 0 YlqD protein Ubiquitin_3 PF14836.1 EPX74262.1 - 1.3 8.7 4.9 1.2 8.8 0.2 3.1 2 2 3 5 5 5 0 Ubiquitin-like domain Seryl_tRNA_N PF02403.17 EPX74262.1 - 8.1 6.5 13.0 3.1 7.8 0.6 3.5 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HMA PF00403.21 EPX74263.1 - 1.8e-10 40.7 0.5 2.1e-10 40.5 0.4 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Tox-PL-2 PF15643.1 EPX74263.1 - 0.0067 16.3 0.0 0.007 16.3 0.0 1.1 1 0 0 1 1 1 1 Papain fold toxin 2 DUF1364 PF07102.7 EPX74263.1 - 0.052 13.4 0.0 0.071 12.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1364) Antimicrobial_7 PF08102.6 EPX74263.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Scorpion antimicrobial peptide CPSF_A PF03178.10 EPX74264.1 - 4.9e-83 278.8 0.0 7.5e-82 274.9 0.0 2.7 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EPX74264.1 - 3.2e-18 65.1 0.3 5.5e-18 64.3 0.2 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RNase_P_Rpp14 PF01900.14 EPX74265.1 - 0.00032 20.5 0.1 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family adh_short PF00106.20 EPX74266.1 - 2.1e-09 37.5 0.0 1.1e-07 31.9 0.0 2.6 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPX74266.1 - 1.3e-06 28.1 0.0 3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPX74266.1 - 0.094 12.4 0.0 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase ATPase_gene1 PF09527.5 EPX74266.1 - 0.33 10.7 3.3 0.2 11.4 0.4 1.9 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Dus PF01207.12 EPX74267.1 - 1e-50 172.3 0.0 1.6e-50 171.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 EPX74267.1 - 0.019 14.0 0.0 0.044 12.9 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI A_deaminase PF00962.17 EPX74267.1 - 0.067 12.0 0.0 0.18 10.6 0.0 1.7 2 1 0 2 2 2 0 Adenosine/AMP deaminase TP_methylase PF00590.15 EPX74267.1 - 0.13 11.9 0.0 0.49 10.0 0.0 1.9 3 0 0 3 3 3 0 Tetrapyrrole (Corrin/Porphyrin) Methylases FAD_binding_4 PF01565.18 EPX74267.1 - 0.14 11.6 0.0 0.46 9.9 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain HSP70 PF00012.15 EPX74268.1 - 9.7e-240 796.5 10.2 1.1e-239 796.4 7.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPX74268.1 - 3.8e-19 68.4 1.5 6.9e-18 64.3 0.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EPX74268.1 - 0.0039 16.8 0.0 0.013 15.1 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EPX74268.1 - 0.013 14.6 0.3 0.04 13.0 0.1 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.6 EPX74268.1 - 0.016 14.1 0.0 0.05 12.5 0.0 1.9 1 0 0 1 1 1 0 StbA protein DDR PF08841.5 EPX74268.1 - 0.041 12.7 4.5 0.11 11.3 0.3 2.9 3 1 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 EPX74268.1 - 0.15 11.8 6.4 3.3 7.5 0.1 4.2 3 2 0 3 3 3 0 Cell division protein FtsA Pro_isomerase PF00160.16 EPX74269.1 - 5e-47 159.9 0.3 5.5e-47 159.8 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3844 PF12955.2 EPX74270.1 - 5.7e-33 113.0 6.6 9.2e-33 112.4 4.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 EPX74270.1 - 1.7 8.8 11.1 6.9 6.9 7.7 2.0 1 1 0 1 1 1 0 EGF-like domain tRNA-synt_1 PF00133.17 EPX74271.1 - 5e-215 715.0 0.2 3.7e-214 712.1 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EPX74271.1 - 2e-32 112.0 0.7 4.5e-32 110.9 0.5 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EPX74271.1 - 5.7e-20 71.3 0.6 7.5e-11 41.3 0.0 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EPX74271.1 - 3.5e-10 39.4 3.4 2.1e-06 27.1 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EPX74271.1 - 9.9e-05 21.3 0.7 0.0078 15.0 0.0 3.1 3 1 1 4 4 4 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EPX74271.1 - 0.00026 20.2 0.0 0.36 9.9 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain DUF837 PF05769.6 EPX74271.1 - 0.03 13.8 0.4 0.99 8.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF837) tRNA-synt_1c PF00749.16 EPX74271.1 - 0.11 11.1 0.0 0.11 11.1 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain Chitin_synth_1 PF01644.12 EPX74272.1 - 5.6e-51 172.5 0.1 8.7e-51 171.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EPX74272.1 - 3.6e-14 52.2 0.0 8.6e-14 50.9 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal PAH PF02671.16 EPX74273.1 - 1.9e-35 120.2 10.1 1.4e-14 53.4 0.0 4.3 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EPX74273.1 - 3.8e-25 87.5 0.5 1.1e-24 86.1 0.3 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Bromodomain PF00439.20 EPX74274.1 - 1.3e-43 146.7 4.2 1.9e-21 75.7 0.8 2.7 2 0 0 2 2 2 2 Bromodomain CKS PF01111.14 EPX74275.1 - 1.4e-34 117.7 0.4 1.8e-34 117.3 0.3 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ATP-synt PF00231.14 EPX74276.1 - 3.8e-66 223.3 7.7 4.4e-66 223.1 5.4 1.0 1 0 0 1 1 1 1 ATP synthase SPT16 PF08644.6 EPX74276.1 - 0.034 13.9 0.1 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DASH_Duo1 PF08651.5 EPX74276.1 - 0.23 11.0 4.2 4 7.0 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF724 PF05266.9 EPX74276.1 - 0.26 10.9 3.1 9.4 5.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Glyco_transf_22 PF03901.12 EPX74277.1 - 6.5e-36 124.2 29.8 8.9e-36 123.7 20.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Inhibitor_I78 PF11720.3 EPX74277.1 - 1.9e-10 40.3 0.0 3.2e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I78 family DUF2924 PF11149.3 EPX74277.1 - 0.051 13.5 0.0 4.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) DnaJ PF00226.26 EPX74278.1 - 4.7e-26 90.3 2.1 8e-26 89.5 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EPX74278.1 - 1.6e-19 69.5 0.2 2e-15 56.4 0.0 3.0 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EPX74278.1 - 7.1e-15 54.8 15.8 1.4e-14 53.8 10.9 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EPX74278.1 - 0.031 13.9 10.4 0.16 11.7 1.6 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 EPX74278.1 - 0.09 12.5 5.9 3.9 7.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbons DUF2614 PF11023.3 EPX74278.1 - 0.9 9.3 4.5 13 5.6 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zf-RING_3 PF14369.1 EPX74278.1 - 3.1 7.8 6.0 23 5.0 0.0 3.6 4 0 0 4 4 4 0 zinc-finger HECT_2 PF09814.4 EPX74279.1 - 1.8e-38 132.1 3.0 2.4e-38 131.7 2.1 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zinc_ribbon_4 PF13717.1 EPX74279.1 - 0.24 11.1 2.0 1.4 8.6 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EPX74279.1 - 0.29 10.7 2.0 1.5 8.4 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain C1_4 PF07975.7 EPX74279.1 - 0.33 10.9 0.1 0.33 10.9 0.1 3.0 2 1 1 3 3 3 0 TFIIH C1-like domain DUF983 PF06170.7 EPX74279.1 - 0.37 10.9 1.8 2.5 8.2 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF983) DZR PF12773.2 EPX74279.1 - 7.6 6.4 7.0 19 5.2 2.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon UAA PF08449.6 EPX74280.1 - 1.6e-87 293.2 20.4 2e-87 292.9 14.1 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPX74280.1 - 4.2e-05 23.5 27.0 0.0001 22.3 5.6 3.2 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 EPX74280.1 - 0.00059 19.5 7.9 0.00059 19.5 5.5 2.5 1 1 0 2 2 2 1 Triose-phosphate Transporter family Orbi_NS3 PF01616.11 EPX74280.1 - 0.0076 15.2 0.7 0.014 14.3 0.5 1.4 1 0 0 1 1 1 1 Orbivirus NS3 RE_ScaI PF09569.5 EPX74280.1 - 0.021 14.3 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 ScaI restriction endonuclease Nuc_sug_transp PF04142.10 EPX74280.1 - 0.076 12.1 13.2 0.13 11.3 7.6 2.3 1 1 1 2 2 2 0 Nucleotide-sugar transporter EmrE PF13536.1 EPX74280.1 - 0.16 12.1 22.4 0.23 11.6 3.4 3.1 3 1 1 4 4 4 0 Multidrug resistance efflux transporter DUF4231 PF14015.1 EPX74280.1 - 0.21 11.5 2.4 0.25 11.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) VHS PF00790.14 EPX74281.1 - 9.1e-29 99.9 2.2 9.1e-29 99.9 1.6 1.7 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.23 EPX74281.1 - 1e-17 63.2 0.3 3.7e-17 61.4 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EPX74281.1 - 6.8e-15 54.3 0.1 1.5e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPX74281.1 - 8.3e-13 47.6 0.1 4e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain UIM PF02809.15 EPX74281.1 - 0.00045 19.5 1.6 0.00045 19.5 1.1 2.5 3 0 0 3 3 3 1 Ubiquitin interaction motif DUF775 PF05603.7 EPX74281.1 - 0.043 13.3 0.9 0.093 12.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF775) GCD14 PF08704.5 EPX74281.1 - 0.34 10.3 2.3 0.48 9.8 1.6 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit TRAPPC-Trs85 PF12739.2 EPX74282.1 - 1.3e-83 280.9 3.3 1.9e-83 280.4 2.3 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SAP PF02037.22 EPX74283.1 - 3.2e-07 29.7 0.0 6.2e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain DUF3507 PF12015.3 EPX74283.1 - 0.0025 17.3 0.1 0.0031 17.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) STOP PF05217.7 EPX74283.1 - 0.057 13.1 0.7 0.069 12.8 0.5 1.1 1 0 0 1 1 1 0 STOP protein ECH_C PF13766.1 EPX74283.1 - 0.093 12.8 0.2 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region zf-RING_2 PF13639.1 EPX74284.1 - 6.7e-09 35.4 15.4 2.6e-08 33.5 8.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPX74284.1 - 3.9e-08 33.1 11.9 3.9e-08 33.1 8.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX74284.1 - 4.5e-07 29.4 13.4 1.4e-06 27.8 5.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX74284.1 - 4.8e-07 29.3 10.7 4.8e-07 29.3 7.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 EPX74284.1 - 1.1e-06 28.0 0.0 2.5e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-RING_6 PF14835.1 EPX74284.1 - 1.6e-06 27.7 2.9 1.6e-06 27.7 2.0 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EPX74284.1 - 1.7e-06 27.6 9.9 1.7e-06 27.6 6.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Sgf11 PF08209.6 EPX74284.1 - 3.1e-05 23.2 1.3 5.2e-05 22.4 0.1 2.0 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C3HC4_4 PF15227.1 EPX74284.1 - 0.00011 22.0 14.3 0.00014 21.6 7.9 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING PRP21_like_P PF12230.3 EPX74284.1 - 0.0026 17.3 2.1 0.0026 17.3 1.4 1.9 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein U-box PF04564.10 EPX74284.1 - 0.0052 16.7 1.4 0.05 13.5 0.0 2.9 3 1 0 3 3 3 1 U-box domain DUF3507 PF12015.3 EPX74284.1 - 0.01 15.3 0.1 0.023 14.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3507) zf-rbx1 PF12678.2 EPX74284.1 - 0.014 15.4 10.0 0.017 15.2 4.6 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EPX74284.1 - 0.019 14.5 4.4 0.019 14.5 3.1 2.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.7 EPX74284.1 - 0.034 14.2 0.2 0.034 14.2 0.1 3.1 3 1 1 4 4 2 0 Drought induced 19 protein (Di19), zinc-binding zf-Apc11 PF12861.2 EPX74284.1 - 0.054 13.3 0.6 0.47 10.3 1.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.7 EPX74284.1 - 0.59 9.9 8.6 4.5 7.1 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbons zf-Nse PF11789.3 EPX74284.1 - 0.7 9.4 10.8 0.11 12.0 3.9 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EPX74284.1 - 0.97 9.2 11.6 0.12 12.1 3.9 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EPX74284.1 - 1.1 8.7 7.4 14 5.3 0.0 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.2 EPX74284.1 - 2 8.2 7.5 11 5.8 2.7 2.6 2 0 0 2 2 2 0 Double zinc ribbon DUF1272 PF06906.6 EPX74284.1 - 3.5 7.5 8.7 2.5 8.0 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DnaJ PF00226.26 EPX74285.1 - 1.2e-13 50.5 0.2 2.8e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Anp1 PF03452.9 EPX74286.1 - 1.5e-111 371.8 0.0 2.1e-111 371.4 0.0 1.2 1 0 0 1 1 1 1 Anp1 Cwf_Cwc_15 PF04889.7 EPX74286.1 - 0.17 11.5 3.7 0.27 10.9 2.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Prominin PF05478.6 EPX74286.1 - 0.24 8.8 0.0 0.33 8.4 0.0 1.1 1 0 0 1 1 1 0 Prominin Pterin_bind PF00809.17 EPX74287.1 - 1.3e-65 220.7 0.0 2.5e-65 219.7 0.0 1.5 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EPX74287.1 - 1e-38 131.9 0.0 2e-38 131.0 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 EPX74287.1 - 7.2e-33 113.1 0.0 1.7e-18 66.8 0.0 2.6 2 0 0 2 2 2 2 Dihydroneopterin aldolase CDC27 PF09507.5 EPX74288.1 - 3.6e-54 184.6 26.3 2e-28 99.7 10.9 2.0 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 NUC153 PF08159.7 EPX74289.1 - 2.5e-13 49.3 14.0 4.9e-13 48.3 0.5 3.8 3 0 0 3 3 3 2 NUC153 domain PEMT PF04191.8 EPX74290.1 - 5.7e-29 100.3 2.2 5.7e-29 100.3 1.5 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF973 PF06157.6 EPX74290.1 - 0.0064 15.4 1.1 0.0086 15.0 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF973) DUF3687 PF12459.3 EPX74290.1 - 0.052 12.8 0.5 0.12 11.6 0.3 1.6 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein YrhK PF14145.1 EPX74290.1 - 0.098 12.3 2.1 0.17 11.5 0.7 2.0 2 1 0 2 2 2 0 YrhK-like protein SpoV PF08183.6 EPX74290.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.2 3 0 0 3 3 3 0 Stage V sporulation protein family COQ7 PF03232.8 EPX74291.1 - 7.7e-72 240.3 0.0 9e-72 240.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 MtaB PF12176.3 EPX74291.1 - 0.094 11.1 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit RNA_pol_Rpb4 PF03874.11 EPX74292.1 - 1.6e-22 79.6 0.1 2e-22 79.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Gtr1_RagA PF04670.7 EPX74293.1 - 3.3e-99 330.7 0.4 4.1e-99 330.4 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EPX74293.1 - 2.9e-08 33.2 0.4 7.3e-08 31.9 0.0 1.9 3 0 0 3 3 3 1 Ras family MMR_HSR1 PF01926.18 EPX74293.1 - 1.8e-07 31.1 0.0 4.9e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.16 EPX74293.1 - 1.5e-06 27.6 0.0 2.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EPX74293.1 - 2.5e-06 27.9 0.0 9.2e-06 26.1 0.0 2.0 2 1 1 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 EPX74293.1 - 6.4e-05 22.4 0.0 9.3e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF815 PF05673.8 EPX74293.1 - 0.0033 16.3 0.3 0.014 14.3 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 EPX74293.1 - 0.013 14.9 0.1 0.032 13.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EPX74293.1 - 0.015 14.7 0.0 0.036 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 EPX74293.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Imm42 PF15601.1 EPX74293.1 - 0.091 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 42 zf-CCCH PF00642.19 EPX74294.1 - 6.5e-06 25.7 29.4 0.00077 19.0 0.8 4.7 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EPX74294.1 - 0.015 14.7 1.8 0.015 14.7 1.2 2.1 2 0 0 2 2 2 0 Putative zinc-finger domain Toxin_41 PF15521.1 EPX74294.1 - 0.018 14.1 0.4 0.029 13.5 0.3 1.2 1 0 0 1 1 1 0 Putative toxin 41 CIAPIN1 PF05093.8 EPX74295.1 - 5.2e-34 116.3 4.7 9.4e-34 115.4 3.3 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Erg28 PF03694.8 EPX74296.1 - 4.7e-38 129.6 2.5 6e-38 129.2 1.7 1.1 1 0 0 1 1 1 1 Erg28 like protein Phage_connector PF05352.7 EPX74296.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Phage Connector (GP10) ubiquitin PF00240.18 EPX74297.1 - 1e-102 335.6 15.6 6.6e-34 115.1 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EPX74297.1 - 1.8e-59 197.2 13.8 2.5e-19 68.7 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPX74297.1 - 6.3e-19 68.0 6.5 9.1e-05 22.6 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPX74297.1 - 9.7e-17 61.1 0.4 0.00058 19.5 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EPX74297.1 - 7e-11 42.0 1.2 0.078 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPX74297.1 - 1.2e-10 41.3 0.7 0.076 13.2 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EPX74297.1 - 5.5e-08 32.7 0.0 1 9.4 0.0 3.9 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EPX74297.1 - 2.1e-05 24.3 2.6 2.8 7.9 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 EPX74297.1 - 0.00019 21.0 0.4 8.8 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) FlgD_ig PF13860.1 EPX74297.1 - 0.00045 19.8 2.4 9.3 6.0 0.0 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 EPX74297.1 - 0.00085 17.7 8.1 1.5 7.0 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain Methyltrans_RNA PF04452.9 EPX74297.1 - 0.00087 18.4 0.1 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase Big_3_3 PF13750.1 EPX74297.1 - 0.011 15.1 0.0 31 3.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) DUF3861 PF12977.2 EPX74297.1 - 0.016 15.3 2.7 31 4.7 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_4 PF13291.1 EPX74297.1 - 0.02 15.2 0.4 68 3.8 0.0 3.2 3 0 0 3 3 3 0 ACT domain GABP-alpha PF11620.3 EPX74297.1 - 0.034 14.1 3.9 27 4.8 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain Tash_PEST PF07708.6 EPX74297.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif CTDII PF01556.13 EPX74297.1 - 0.049 13.5 9.1 5 7.0 0.2 3.4 1 1 2 3 3 3 0 DnaJ C terminal domain EMG1 PF03587.9 EPX74297.1 - 0.06 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase FERM_N PF09379.5 EPX74297.1 - 0.093 12.7 8.5 28 4.8 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 EPX74297.1 - 0.29 11.1 3.6 70 3.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) CDC48_2 PF02933.12 EPX74297.1 - 3.3 7.4 7.5 46 3.7 0.1 3.1 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 KID PF02524.9 EPX74297.1 - 6.9 7.2 8.1 2.1e+02 2.8 0.1 4.8 3 0 0 3 3 3 0 KID repeat Peptidase_M14 PF00246.19 EPX74298.1 - 2.4e-65 220.8 0.0 3.2e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Cwf_Cwc_15 PF04889.7 EPX74299.1 - 2.1e-67 227.4 37.5 1.1e-66 225.0 26.0 1.8 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 EPX74299.1 - 0.47 8.8 30.2 0.54 8.6 20.9 1.1 1 0 0 1 1 1 0 Daxx Family DUF3801 PF12687.2 EPX74299.1 - 2.3 7.7 20.4 3.3 7.2 14.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) DUF663 PF04950.7 EPX74299.1 - 2.5 6.9 6.5 3.7 6.4 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF663) Parvo_coat PF00740.13 EPX74299.1 - 3.8 6.3 7.5 4.6 6.0 5.2 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 GET2 PF08690.5 EPX74299.1 - 5.1 6.2 11.6 6.8 5.8 8.0 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Cpn60_TCP1 PF00118.19 EPX74300.1 - 7.7e-135 450.2 4.6 8.7e-135 450.0 3.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HTH_31 PF13560.1 EPX74300.1 - 0.15 12.2 0.0 2 8.6 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain Pkinase PF00069.20 EPX74301.1 - 7.9e-43 146.4 0.0 1e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74301.1 - 3.1e-24 85.4 0.0 5.7e-24 84.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX74301.1 - 0.0021 17.0 0.3 0.22 10.4 0.2 3.0 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPX74301.1 - 0.021 13.9 0.0 0.049 12.7 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX74301.1 - 0.058 13.1 0.1 1.1 8.8 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family CTD_bind PF04818.8 EPX74302.1 - 1.4e-18 66.8 0.7 1.9e-17 63.2 0.2 2.5 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.3 EPX74302.1 - 0.0065 16.1 1.3 0.016 14.8 0.1 2.1 2 1 0 2 2 2 1 CTD kinase subunit gamma CTK3 Cadherin_C PF01049.12 EPX74302.1 - 0.021 14.8 3.5 0.049 13.6 2.1 1.8 1 1 0 1 1 1 0 Cadherin cytoplasmic region SKIP_SNW PF02731.10 EPX74302.1 - 0.045 13.1 1.5 0.11 11.8 1.0 1.6 1 0 0 1 1 1 0 SKIP/SNW domain DUF3277 PF11681.3 EPX74302.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Sugarporin_N PF11471.3 EPX74302.1 - 0.099 12.3 1.2 0.21 11.2 0.8 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension NPV_P10 PF05531.7 EPX74302.1 - 9.6 6.5 8.1 1 9.6 0.7 2.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Adaptin_N PF01602.15 EPX74303.1 - 7.1e-88 295.2 11.7 1.1e-87 294.5 8.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EPX74303.1 - 4e-57 191.5 0.0 9.9e-57 190.2 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EPX74303.1 - 4.7e-53 178.6 0.1 1.6e-52 176.9 0.1 2.0 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EPX74303.1 - 1.9e-08 34.4 0.4 7e-05 23.0 0.0 4.2 2 1 2 4 4 4 1 HEAT repeats Cnd1 PF12717.2 EPX74303.1 - 4.4e-05 23.4 7.1 0.011 15.5 1.3 4.0 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EPX74303.1 - 0.0014 18.4 0.0 1.2 9.3 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HsdM_N PF12161.3 EPX74303.1 - 0.0081 16.5 0.0 0.052 13.9 0.0 2.4 2 0 0 2 2 2 1 HsdM N-terminal domain ParcG PF10274.4 EPX74303.1 - 0.04 13.8 2.2 6.4 6.6 0.0 2.9 3 0 0 3 3 3 0 Parkin co-regulated protein Myosin_head PF00063.16 EPX74304.1 - 6.9e-226 751.5 3.6 1.2e-225 750.7 2.5 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EPX74304.1 - 2.5e-51 173.8 0.1 4.6e-51 172.9 0.0 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EPX74304.1 - 1.3e-13 50.1 0.7 6.7e-13 47.8 0.1 2.5 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 EPX74304.1 - 1.9e-11 43.3 0.1 1.9e-10 40.1 0.0 2.6 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.12 EPX74304.1 - 4.2e-09 35.7 0.0 1.4e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EPX74304.1 - 0.0037 17.4 0.0 0.015 15.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPX74304.1 - 0.011 16.5 0.0 0.036 14.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EPX74304.1 - 0.016 14.3 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 EPX74304.1 - 0.018 14.3 0.2 3.9 6.7 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF605 PF04652.11 EPX74304.1 - 0.031 13.6 15.4 0.06 12.7 10.7 1.4 1 0 0 1 1 1 0 Vta1 like SH3_3 PF08239.6 EPX74304.1 - 0.075 13.2 0.3 0.25 11.5 0.2 1.9 1 0 0 1 1 1 0 Bacterial SH3 domain AAA_16 PF13191.1 EPX74304.1 - 0.16 11.9 0.0 0.66 9.9 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain IQ PF00612.22 EPX74304.1 - 2.9 7.7 9.4 1.8 8.4 4.4 2.3 1 1 1 2 2 2 0 IQ calmodulin-binding motif FAD_binding_3 PF01494.14 EPX74305.1 - 7.1e-23 81.2 0.0 5.2e-21 75.1 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EPX74305.1 - 8.5e-05 21.6 0.0 0.27 10.1 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EPX74305.1 - 0.0017 18.4 0.0 0.0085 16.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EPX74305.1 - 0.0031 16.3 0.0 0.0046 15.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 EPX74305.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPX74305.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EPX74305.1 - 0.023 13.8 0.0 0.046 12.8 0.0 1.5 1 1 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 EPX74305.1 - 0.027 14.4 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Fasciclin PF02469.17 EPX74306.1 - 1.7e-07 31.2 0.0 2.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain Amino_oxidase PF01593.19 EPX74308.1 - 1.2e-45 156.4 0.0 2.3e-39 135.7 0.0 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.12 EPX74308.1 - 7.7e-14 51.5 0.0 3.5e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain HMG_box PF00505.14 EPX74308.1 - 4.1e-05 23.7 0.2 0.0001 22.5 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box NAD_binding_8 PF13450.1 EPX74308.1 - 4.9e-05 23.2 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPX74308.1 - 0.001 19.1 0.0 0.51 10.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPX74308.1 - 0.003 16.5 0.0 0.0082 15.0 0.0 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPX74308.1 - 0.0032 17.2 0.0 0.44 10.3 0.0 2.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding HMG_box_2 PF09011.5 EPX74308.1 - 0.034 14.5 0.5 0.1 12.9 0.2 2.0 1 1 0 1 1 1 0 HMG-box domain Pyr_redox_2 PF07992.9 EPX74308.1 - 0.036 13.9 0.1 0.09 12.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase eIF-1a PF01176.14 EPX74309.1 - 2.8e-19 68.2 0.1 3.7e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF3567 PF12091.3 EPX74309.1 - 0.037 14.0 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) RRM_1 PF00076.17 EPX74310.1 - 7.4e-27 92.7 2.5 1.1e-18 66.5 0.2 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74310.1 - 5.1e-19 68.0 0.1 1e-09 38.2 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74310.1 - 2.1e-17 62.6 0.1 7.5e-08 32.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0261 PF06792.6 EPX74310.1 - 0.12 10.8 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) DUF1777 PF08648.7 EPX74310.1 - 5.2 6.7 35.1 8.9 6.0 24.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) VRR_NUC PF08774.6 EPX74311.1 - 2.7e-15 56.2 0.0 6e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain Nup54 PF13874.1 EPX74311.1 - 0.1 12.2 1.0 2.4 7.8 1.3 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 CWC25 PF12542.3 EPX74312.1 - 2.5e-22 79.1 5.5 2.5e-22 79.1 3.8 3.3 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EPX74312.1 - 2.9e-14 52.7 12.4 2.9e-14 52.7 8.6 4.0 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Evr1_Alr PF04777.8 EPX74313.1 - 7.3e-14 51.4 0.0 1.3e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Erv1 / Alr family SMC_N PF02463.14 EPX74314.1 - 8.5e-67 224.6 52.1 4.1e-37 127.5 5.3 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPX74314.1 - 1.8e-27 95.6 0.0 1.8e-27 95.6 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EPX74314.1 - 1e-14 55.3 2.8 1e-14 55.3 1.9 6.6 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 EPX74314.1 - 2.2e-07 31.1 42.4 2.2e-06 27.8 4.6 4.8 2 2 1 3 3 3 2 AAA domain AAA_29 PF13555.1 EPX74314.1 - 2.7e-05 23.5 0.0 6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 EPX74314.1 - 0.00081 19.0 14.0 0.00081 19.0 9.7 7.3 2 2 4 6 6 6 2 IncA protein CCDC155 PF14662.1 EPX74314.1 - 0.0047 16.5 20.1 0.0047 16.5 13.9 6.6 3 2 3 6 6 6 2 Coiled-coil region of CCDC155 CcmH PF03918.9 EPX74314.1 - 6 5.8 11.3 0.18 10.7 0.3 3.4 4 0 0 4 4 4 0 Cytochrome C biogenesis protein Med15_fungi PF05397.7 EPX74316.1 - 1.3e-28 99.2 3.6 1.3e-28 99.2 2.5 4.2 6 0 0 6 6 6 1 Mediator complex subunit 15 DapB_C PF05173.9 EPX74316.1 - 0.063 13.0 0.4 0.15 11.7 0.3 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus PUF PF00806.14 EPX74317.1 - 5.7e-18 63.3 0.0 0.00096 18.5 0.0 4.6 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EPX74317.1 - 2.3e-10 39.9 0.0 8.5e-10 38.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74317.1 - 1.7e-08 34.3 0.1 5e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74317.1 - 0.00018 21.3 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.8 EPX74318.1 - 9.5e-36 123.6 30.3 1.2e-35 123.3 21.0 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 EPX74318.1 - 1.4e-11 43.7 0.0 2.6e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain NUDIX PF00293.23 EPX74319.1 - 1.6e-16 60.1 0.0 1.8e-12 47.0 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain ZZ PF00569.12 EPX74320.1 - 2.6e-23 81.3 46.3 6.1e-10 38.4 7.8 3.8 3 0 0 3 3 3 3 Zinc finger, ZZ type C1_3 PF07649.7 EPX74320.1 - 0.73 9.9 43.6 1.4 8.9 4.8 3.8 3 0 0 3 3 3 0 C1-like domain SNF2_N PF00176.18 EPX74321.1 - 3.8e-59 199.9 1.5 6.2e-59 199.2 1.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 EPX74321.1 - 1e-15 57.3 7.3 1e-15 57.3 5.1 2.1 1 1 1 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 EPX74321.1 - 2.9e-15 55.8 0.0 7.1e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX74321.1 - 5.1e-06 26.4 0.1 3.4e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Chromo PF00385.19 EPX74321.1 - 6.2e-06 25.8 3.9 0.00053 19.5 0.6 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EPX74321.1 - 2.4e-05 23.9 8.1 2.4e-05 23.9 5.6 2.5 4 0 0 4 4 4 1 PHD-finger zf-PHD-like PF15446.1 EPX74321.1 - 0.064 12.5 11.4 0.84 8.9 4.5 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain AAA_22 PF13401.1 EPX74321.1 - 0.11 12.6 0.0 0.59 10.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain zf-U1 PF06220.7 EPX74322.1 - 1.7e-22 78.6 1.3 3e-22 77.8 0.9 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EPX74322.1 - 0.13 12.4 0.5 0.13 12.4 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-CCHC PF00098.18 EPX74323.1 - 2.2e-08 33.6 29.1 2.8e-05 23.8 2.5 5.0 5 1 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.1 EPX74323.1 - 0.0012 18.4 32.6 0.034 13.8 0.2 5.4 4 1 1 5 5 5 3 Zinc knuckle Sec61_beta PF03911.11 EPX74323.1 - 0.015 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Sec61beta family zf-CCHC_6 PF15288.1 EPX74323.1 - 0.094 12.4 24.7 0.19 11.4 1.7 4.2 1 1 3 4 4 4 0 Zinc knuckle TPP_enzyme_N PF02776.13 EPX74324.1 - 6.3e-56 188.5 0.4 5.3e-55 185.5 0.0 2.5 3 1 1 4 4 4 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EPX74324.1 - 6.1e-50 168.7 0.0 3e-48 163.2 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPX74324.1 - 3.7e-40 136.8 0.0 6.9e-39 132.7 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 EPX74324.1 - 0.085 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit XFP_N PF09364.5 EPX74324.1 - 0.097 11.1 0.0 0.18 10.2 0.0 1.4 1 0 0 1 1 1 0 XFP N-terminal domain Nucleoporin_C PF03177.9 EPX74325.1 - 1.1e-28 100.0 12.0 1.9e-28 99.3 8.3 1.4 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EPX74325.1 - 1.6e-26 93.0 0.3 2.8e-26 92.2 0.2 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.20 EPX74326.1 - 3.8e-35 121.2 0.0 5.5e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74326.1 - 2.2e-11 43.3 0.0 2.9e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX74326.1 - 0.00027 20.7 0.0 0.0068 16.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RNase_H2_suC PF08615.6 EPX74327.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PITH PF06201.8 EPX74328.1 - 1.8e-38 131.6 0.0 2.2e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain DUF3153 PF11353.3 EPX74328.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Shugoshin_N PF07558.6 EPX74329.1 - 3.2e-07 29.9 9.3 6.7e-07 28.9 6.4 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EPX74329.1 - 2.3e-05 23.7 6.8 2.3e-05 23.7 4.7 2.4 2 0 0 2 2 2 1 Shugoshin C terminus TMCO5 PF14992.1 EPX74329.1 - 0.0015 17.7 3.1 0.0015 17.7 2.1 2.1 2 0 0 2 2 2 1 TMCO5 family CpeS PF09367.5 EPX74329.1 - 0.039 13.8 0.5 0.085 12.7 0.1 1.7 2 0 0 2 2 2 0 CpeS-like protein DUF342 PF03961.8 EPX74329.1 - 0.42 8.9 6.7 0.093 11.1 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Ecl1 PF12855.2 EPX74330.1 - 0.003 16.8 9.0 0.013 14.7 6.3 2.2 1 1 0 1 1 1 1 Life-span regulatory factor zf-NF-X1 PF01422.12 EPX74330.1 - 0.048 13.6 4.7 0.1 12.5 3.3 1.5 1 0 0 1 1 1 0 NF-X1 type zinc finger WD40 PF00400.27 EPX74331.1 - 7.3e-17 60.5 6.0 0.0024 17.6 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Proteasome PF00227.21 EPX74332.1 - 3.1e-46 157.0 0.0 4.1e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPX74332.1 - 1.6e-14 52.8 0.1 2.5e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature LexA_DNA_bind PF01726.11 EPX74332.1 - 0.11 12.0 0.0 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 LexA DNA binding domain Pex16 PF08610.5 EPX74333.1 - 5.6e-46 157.0 7.6 7e-46 156.7 5.3 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) ORC5_C PF14630.1 EPX74334.1 - 4.8e-66 222.9 0.1 6.3e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EPX74334.1 - 6e-08 32.8 0.0 1.5e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPX74334.1 - 5.2e-06 26.6 0.4 1.8e-05 24.9 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EPX74334.1 - 0.00013 21.8 0.1 0.0003 20.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPX74334.1 - 0.0028 17.4 0.1 0.029 14.0 0.1 2.1 1 1 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 EPX74334.1 - 0.09 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain CBS PF00571.23 EPX74335.1 - 1.1e-19 69.9 0.0 3.2e-06 26.8 0.0 4.4 4 0 0 4 4 4 4 CBS domain RasGAP PF00616.14 EPX74336.1 - 7.4e-48 162.8 2.9 1.8e-47 161.5 0.2 2.4 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EPX74336.1 - 1.9e-18 66.4 0.7 1.9e-18 66.4 0.5 2.2 2 0 0 2 2 2 1 RasGAP C-terminus DUF972 PF06156.8 EPX74336.1 - 0.014 15.7 2.6 1.6 9.0 0.1 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF972) Cpn60_TCP1 PF00118.19 EPX74337.1 - 2.8e-148 494.5 2.2 3.2e-148 494.3 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nop PF01798.13 EPX74338.1 - 1.2e-59 199.9 0.0 4.3e-59 198.1 0.0 1.9 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 EPX74338.1 - 4.8e-26 90.3 0.2 1.3e-25 88.9 0.1 1.8 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EPX74338.1 - 1.2e-21 76.6 0.3 1.2e-21 76.6 0.2 2.5 2 1 0 2 2 2 1 NOP5NT (NUC127) domain SMP_2 PF10144.4 EPX74338.1 - 0.054 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin GAGA_bind PF06217.7 EPX74338.1 - 0.39 10.6 12.1 0.64 9.9 8.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 EPX74338.1 - 3.7 7.1 35.4 8.2 6.0 24.5 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 eIF3_N PF09440.5 EPX74339.1 - 7.1e-50 168.6 7.0 1.1e-49 167.9 2.1 2.4 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EPX74339.1 - 0.00091 19.5 0.3 0.0036 17.5 0.2 2.1 1 0 0 1 1 1 1 PCI domain IF2_N PF04760.10 EPX74339.1 - 0.0029 17.2 1.6 0.19 11.3 0.0 3.6 3 1 0 3 3 3 1 Translation initiation factor IF-2, N-terminal region PCI_Csn8 PF10075.4 EPX74339.1 - 0.0073 16.0 0.1 0.02 14.6 0.1 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Mito_fiss_reg PF05308.6 EPX74339.1 - 0.051 12.9 1.0 0.092 12.1 0.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator BAR_3_WASP_bdg PF10456.4 EPX74339.1 - 0.052 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein RP-C_C PF11800.3 EPX74339.1 - 0.12 12.0 2.3 1.4 8.5 0.4 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region Antimicrobial21 PF14861.1 EPX74339.1 - 0.13 11.7 0.2 0.23 10.9 0.2 1.4 1 0 0 1 1 1 0 Plant antimicrobial peptide Alpha_GJ PF03229.8 EPX74339.1 - 0.27 11.5 3.7 0.49 10.7 2.6 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J YlqD PF11068.3 EPX74339.1 - 1.2 9.1 4.7 4 7.4 0.4 3.0 3 0 0 3 3 3 0 YlqD protein Oxysterol_BP PF01237.13 EPX74340.1 - 1.4e-55 188.2 0.0 3e-42 144.3 0.0 2.2 2 0 0 2 2 2 2 Oxysterol-binding protein Steroid_dh PF02544.11 EPX74341.1 - 1.3e-44 151.6 8.4 2.1e-44 150.9 5.8 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 EPX74341.1 - 5.9e-05 22.3 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family PEMT PF04191.8 EPX74341.1 - 0.00063 19.8 0.3 0.0016 18.5 0.2 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 EPX74341.1 - 0.02 14.1 1.4 0.035 13.3 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Glyco_hydro_71 PF03659.9 EPX74342.1 - 1e-97 327.0 13.2 1.2e-97 326.8 9.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 SQS_PSY PF00494.14 EPX74343.1 - 1.8e-42 145.5 0.0 2.3e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF2303 PF10065.4 EPX74343.1 - 0.049 12.4 0.1 0.1 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) PAP_central PF04928.12 EPX74344.1 - 1.8e-106 354.5 0.0 3.1e-106 353.8 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EPX74344.1 - 1.1e-51 174.4 0.7 1.1e-51 174.4 0.5 1.8 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EPX74344.1 - 8.6e-11 42.0 0.0 2.7e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Amidase PF01425.16 EPX74345.1 - 1.8e-103 346.8 0.0 2e-103 346.6 0.0 1.0 1 0 0 1 1 1 1 Amidase AAA_12 PF13087.1 EPX74346.1 - 2.8e-08 33.3 0.0 7.9e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPX74346.1 - 0.00044 19.9 0.0 0.00086 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPX74346.1 - 0.024 14.6 0.0 0.062 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain FAT PF02259.18 EPX74347.1 - 6e-121 403.7 8.7 6e-121 403.7 6.0 3.2 3 1 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.22 EPX74347.1 - 4.3e-61 206.3 0.2 7.1e-61 205.6 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EPX74347.1 - 1e-60 204.3 0.3 1e-60 204.3 0.2 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EPX74347.1 - 1.4e-42 143.8 1.5 2.8e-42 142.8 0.0 2.4 2 0 0 2 2 2 1 Rapamycin binding domain FATC PF02260.15 EPX74347.1 - 1.9e-15 55.9 0.9 5e-15 54.6 0.6 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 EPX74347.1 - 4.1e-13 49.4 13.3 0.00087 19.5 0.0 10.3 7 3 3 11 11 11 5 HEAT repeats HEAT PF02985.17 EPX74347.1 - 4.5e-13 48.0 19.7 0.1 12.7 0.0 11.7 13 0 0 13 13 10 3 HEAT repeat HEAT_EZ PF13513.1 EPX74347.1 - 3.4e-09 36.9 21.2 0.00024 21.4 0.0 13.3 16 1 2 18 18 15 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPX74347.1 - 0.00066 20.0 3.9 2.4 8.6 0.0 5.9 7 1 0 7 7 5 1 Vacuolar 14 Fab1-binding region Apc3 PF12895.2 EPX74347.1 - 0.0026 17.8 4.6 0.83 9.8 0.3 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EPX74347.1 - 0.014 15.1 1.2 5.7 7.0 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Dyp_perox PF04261.7 EPX74347.1 - 0.37 9.4 0.0 1.1 7.9 0.0 1.7 2 0 0 2 2 2 0 Dyp-type peroxidase family CLASP_N PF12348.3 EPX74347.1 - 1.5 8.1 10.3 0.94 8.7 0.0 4.7 6 0 0 6 6 6 0 CLASP N terminal TPR_2 PF07719.12 EPX74347.1 - 5.6 7.1 9.4 14 5.8 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TIMELESS PF04821.9 EPX74348.1 - 5.4e-65 219.2 12.8 1.7e-64 217.6 5.0 2.4 2 0 0 2 2 2 2 Timeless protein PI3_PI4_kinase PF00454.22 EPX74349.1 - 5.4e-60 202.7 0.1 1.2e-59 201.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EPX74349.1 - 4e-37 128.0 4.6 7.2e-37 127.1 3.2 1.4 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EPX74349.1 - 1.1e-21 76.7 0.1 1.1e-21 76.7 0.1 3.3 4 1 1 5 5 5 1 UME (NUC010) domain FATC PF02260.15 EPX74349.1 - 4.9e-14 51.4 0.0 1.1e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_16 PF13432.1 EPX74349.1 - 6.4e-07 29.8 0.2 0.082 13.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPX74349.1 - 0.032 13.8 4.2 4 7.1 0.0 3.4 3 0 0 3 3 3 0 TPR repeat TPR_19 PF14559.1 EPX74349.1 - 0.033 14.5 0.1 0.49 10.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPX74349.1 - 0.069 12.9 0.9 11 6.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPX74349.1 - 0.075 13.7 1.3 4.8 8.0 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPX74349.1 - 0.1 13.0 0.2 0.53 10.8 0.0 2.5 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPX74349.1 - 0.16 11.9 3.0 7.8 6.6 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPX74349.1 - 0.7 9.8 6.7 16 5.4 0.8 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat SelR PF01641.13 EPX74350.1 - 5.4e-49 165.0 0.2 6.9e-49 164.6 0.1 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 EPX74350.1 - 0.011 15.5 1.1 0.23 11.2 1.3 2.4 1 1 1 2 2 2 0 Double zinc ribbon DUF2296 PF10058.4 EPX74350.1 - 0.049 13.3 3.3 2.3 8.0 0.1 3.0 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Cas_CXXC_CXXC PF09706.5 EPX74350.1 - 0.07 13.3 0.0 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) TF_Zn_Ribbon PF08271.7 EPX74350.1 - 0.071 12.4 4.1 0.44 9.8 0.1 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding NOB1_Zn_bind PF08772.6 EPX74350.1 - 0.09 12.6 1.6 0.76 9.6 0.2 2.5 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like NAD_binding_10 PF13460.1 EPX74351.1 - 2.4e-24 86.3 0.0 3e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPX74351.1 - 3.1e-06 26.8 0.0 3.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPX74351.1 - 0.00069 18.6 0.0 0.00088 18.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EPX74351.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 EPX74351.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Mcp5_PH PF12814.2 EPX74352.1 - 3.2e-26 91.6 0.1 7.9e-26 90.3 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3573 PF12097.3 EPX74352.1 - 1.2 7.7 11.6 0.17 10.4 4.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) DivIC PF04977.10 EPX74352.1 - 1.4 8.4 12.0 0.063 12.7 1.0 3.1 2 1 0 2 2 2 0 Septum formation initiator SMK-1 PF04802.10 EPX74353.1 - 2.3e-73 245.8 6.8 5.4e-73 244.6 4.7 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 SE PF08491.5 EPX74354.1 - 3e-109 364.1 0.0 4.1e-109 363.6 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EPX74354.1 - 7.2e-11 41.5 0.0 4.8e-07 29.0 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPX74354.1 - 5.6e-10 38.8 0.0 6e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EPX74354.1 - 4.4e-06 26.6 0.5 1.1e-05 25.3 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EPX74354.1 - 1.8e-05 23.8 0.6 7.3e-05 21.7 0.4 1.8 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EPX74354.1 - 6.4e-05 21.9 0.6 0.0005 19.0 0.7 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EPX74354.1 - 0.00013 21.1 0.3 0.00032 19.8 0.1 1.7 2 0 0 2 2 2 1 Thi4 family GDI PF00996.13 EPX74354.1 - 0.00029 19.2 0.0 0.00043 18.7 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Pyr_redox PF00070.22 EPX74354.1 - 0.00062 20.1 0.3 0.0012 19.1 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPX74354.1 - 0.00097 18.3 0.0 0.0012 17.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPX74354.1 - 0.0013 18.6 0.1 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPX74354.1 - 0.0025 16.7 0.1 0.015 14.1 0.2 2.0 3 0 0 3 3 3 1 Lycopene cyclase protein Shikimate_DH PF01488.15 EPX74354.1 - 0.004 17.2 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EPX74354.1 - 0.0053 16.2 0.2 0.0088 15.4 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EPX74354.1 - 0.015 15.3 0.7 0.087 12.8 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EPX74354.1 - 0.023 14.4 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 EPX74354.1 - 0.031 12.7 0.3 0.042 12.3 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 EPX74354.1 - 0.088 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EPX74354.1 - 0.1 11.2 0.4 0.38 9.3 0.4 1.8 2 1 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.16 EPX74354.1 - 0.11 12.3 0.1 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family GMC_oxred_N PF00732.14 EPX74354.1 - 0.11 11.6 0.0 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase DUF4422 PF14393.1 EPX74355.1 - 0.019 14.5 1.3 0.02 14.4 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) DUF3899 PF13038.1 EPX74355.1 - 1.1 9.5 3.0 1.5 9.0 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Pmp3 PF01679.12 EPX74356.1 - 2.7e-25 87.8 7.1 2.9e-25 87.6 4.9 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pam16 PF03656.8 EPX74357.1 - 2.4e-34 117.8 0.9 2.7e-34 117.6 0.6 1.0 1 0 0 1 1 1 1 Pam16 Exonuc_VII_S PF02609.11 EPX74358.1 - 0.00042 20.0 3.5 0.00042 20.0 2.5 4.2 4 1 1 5 5 5 1 Exonuclease VII small subunit Surfac_D-trimer PF09006.6 EPX74358.1 - 0.085 12.5 0.1 0.085 12.5 0.1 3.1 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation Reo_sigmaC PF04582.7 EPX74358.1 - 4 6.5 10.3 16 4.5 4.2 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TOM13 PF08219.6 EPX74359.1 - 8.6e-18 63.8 0.1 9.2e-18 63.7 0.1 1.0 1 0 0 1 1 1 1 Outer membrane protein TOM13 Metallophos PF00149.23 EPX74360.1 - 0.00021 20.7 3.2 0.00071 19.0 2.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPX74360.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DNA_ligase_A_M PF01068.16 EPX74361.1 - 1.1e-52 178.3 0.1 2e-52 177.5 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPX74361.1 - 8.7e-38 129.8 0.0 1.8e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPX74361.1 - 8.7e-15 54.9 0.0 2e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 EPX74361.1 - 0.0022 17.7 0.6 0.021 14.5 0.4 2.3 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain WD40 PF00400.27 EPX74362.1 - 7.4e-28 95.3 6.3 2.2e-08 33.6 0.0 5.7 6 1 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EPX74362.1 - 2.1e-06 27.3 0.0 0.00091 18.7 0.0 2.8 1 1 1 2 2 2 2 PQQ-like domain eIF2A PF08662.6 EPX74362.1 - 2.5e-05 24.0 0.4 2.6 7.6 0.0 3.9 1 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ PF01011.16 EPX74362.1 - 3.4e-05 23.1 0.2 0.018 14.5 0.0 4.2 5 0 0 5 5 5 1 PQQ enzyme repeat BBS2_Mid PF14783.1 EPX74362.1 - 0.00023 20.8 0.2 1.6 8.5 0.0 4.0 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EPX74362.1 - 0.0086 16.3 0.0 3 8.2 0.0 3.1 2 0 0 2 2 2 1 PQQ-like domain Coatomer_WDAD PF04053.9 EPX74362.1 - 0.037 12.8 0.6 2.1 7.0 0.1 2.9 1 1 2 3 3 3 0 Coatomer WD associated region WD40 PF00400.27 EPX74363.1 - 4.5e-50 165.8 30.1 1.1e-12 47.2 0.1 11.5 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.7 EPX74363.1 - 3.1e-23 81.7 0.2 5.3e-23 81.0 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nbas_N PF15492.1 EPX74363.1 - 0.00021 20.4 0.4 0.24 10.4 0.0 4.1 3 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal FAD-oxidase_C PF02913.14 EPX74364.1 - 1.4e-64 217.8 0.0 1.9e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EPX74364.1 - 7.9e-33 112.8 0.1 1.3e-32 112.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain USP7_ICP0_bdg PF12436.3 EPX74365.1 - 2.4e-67 226.7 0.4 2.5e-64 216.8 0.1 2.6 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 EPX74365.1 - 1.4e-57 194.8 0.9 2.9e-57 193.8 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EPX74365.1 - 1.3e-56 191.4 9.1 3.3e-55 186.8 0.3 3.0 3 1 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 EPX74365.1 - 2e-31 109.5 0.0 4e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EPX74365.1 - 5.4e-09 36.3 0.0 6.4e-07 29.6 0.0 4.0 2 2 1 3 3 3 1 MATH domain FliC PF12445.3 EPX74365.1 - 2.9 8.0 5.8 0.32 11.1 0.0 2.4 4 0 0 4 4 4 0 Flagellin protein Mid2 PF04478.7 EPX74366.1 - 0.00019 20.9 0.0 0.00042 19.7 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.1 EPX74366.1 - 0.00097 18.8 1.4 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 TMEM154 protein family Syndecan PF01034.15 EPX74366.1 - 0.002 17.7 0.1 0.005 16.4 0.1 1.6 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.13 EPX74366.1 - 0.0024 17.6 2.0 0.0029 17.3 0.0 2.2 2 1 1 3 3 3 1 Glycophorin A SKG6 PF08693.5 EPX74366.1 - 0.02 14.2 0.5 0.02 14.2 0.4 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Plasmodium_Vir PF05795.6 EPX74366.1 - 0.032 13.4 3.0 0.038 13.1 0.2 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein FAM163 PF15069.1 EPX74366.1 - 0.044 14.3 0.2 0.26 11.8 0.0 2.2 2 1 0 2 2 2 0 FAM163 family Rifin_STEVOR PF02009.11 EPX74366.1 - 0.056 13.0 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family Tmemb_9 PF05434.6 EPX74366.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 TMEM9 EphA2_TM PF14575.1 EPX74366.1 - 0.07 13.5 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_M50 PF02163.17 EPX74366.1 - 0.099 11.5 0.0 0.099 11.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 SGS PF05002.10 EPX74367.1 - 3.4e-30 103.6 2.5 3.4e-30 103.6 1.7 2.4 3 0 0 3 3 3 1 SGS domain CS PF04969.11 EPX74367.1 - 1.4e-14 54.3 0.2 2.5e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 CS domain PRELI PF04707.9 EPX74368.1 - 4.7e-53 178.9 0.3 5.4e-53 178.7 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family DUF3449 PF11931.3 EPX74369.1 - 1.5e-78 262.8 1.2 5.2e-75 251.2 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3449) zf-met PF12874.2 EPX74369.1 - 4e-08 33.2 4.4 5.3e-06 26.4 1.7 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPX74369.1 - 1.1e-07 31.7 11.5 1e-06 28.6 4.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding SF3a60_bindingd PF12108.3 EPX74369.1 - 1.5e-05 24.4 0.4 3.9e-05 23.0 0.2 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-DBF PF07535.7 EPX74369.1 - 0.0025 17.4 1.2 0.0025 17.4 0.8 2.4 2 0 0 2 2 2 1 DBF zinc finger zf-C2H2_2 PF12756.2 EPX74369.1 - 0.0053 16.8 4.1 0.1 12.7 1.1 2.8 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) COG2 PF06148.6 EPX74370.1 - 7e-16 58.3 5.8 1.1e-15 57.6 4.0 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Med4 PF10018.4 EPX74370.1 - 0.0087 15.4 3.0 0.015 14.7 2.1 1.5 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Zw10 PF06248.8 EPX74370.1 - 0.0097 14.1 1.3 0.011 13.8 0.9 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 IncA PF04156.9 EPX74370.1 - 0.026 14.1 3.9 0.033 13.7 2.2 1.5 1 1 0 1 1 1 0 IncA protein CCDC-167 PF15188.1 EPX74370.1 - 0.032 14.1 4.6 0.54 10.2 1.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TelA PF05816.6 EPX74370.1 - 0.034 12.8 4.8 0.046 12.4 3.3 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Vps51 PF08700.6 EPX74370.1 - 0.041 13.7 3.4 0.19 11.6 0.2 2.7 1 1 1 2 2 2 0 Vps51/Vps67 Sec8_exocyst PF04048.9 EPX74370.1 - 0.083 12.5 3.7 0.18 11.4 2.1 1.9 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Occludin_ELL PF07303.8 EPX74370.1 - 0.32 11.7 3.1 0.72 10.6 2.1 1.7 1 1 0 1 1 1 0 Occludin homology domain GLTP PF08718.6 EPX74370.1 - 0.36 10.8 3.0 1.4 8.9 2.0 1.9 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) IKI3 PF04762.7 EPX74371.1 - 1.4e-292 972.9 0.0 2.1e-292 972.3 0.0 1.3 1 0 0 1 1 1 1 IKI3 family Clathrin PF00637.15 EPX74371.1 - 0.0021 17.6 9.0 0.03 13.9 0.0 4.1 1 1 3 4 4 4 2 Region in Clathrin and VPS DUF928 PF06051.7 EPX74371.1 - 0.063 12.8 0.4 11 5.6 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) polyprenyl_synt PF00348.12 EPX74372.1 - 6.1e-49 166.1 0.0 8.1e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase QueC PF06508.8 EPX74372.1 - 0.09 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Hist_deacetyl PF00850.14 EPX74373.1 - 1.2e-81 274.4 0.4 1.6e-81 274.0 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF1256 PF06866.6 EPX74373.1 - 0.068 12.3 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) PALP PF00291.20 EPX74374.1 - 9.1e-62 209.0 0.0 1.1e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DEAD PF00270.24 EPX74375.1 - 1.2e-43 148.5 0.0 2.4e-43 147.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX74375.1 - 2.2e-24 85.1 0.0 5.5e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EPX74375.1 - 5.8e-23 80.2 0.1 1.2e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EPX74375.1 - 3.2e-06 27.1 0.1 3.9e-05 23.5 0.0 2.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit TFIID_30kDa PF03540.8 EPX74376.1 - 1.1e-24 85.9 0.1 1.8e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CDC45 PF02724.9 EPX74376.1 - 1.3 6.9 4.4 1.3 6.9 3.0 1.0 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 EPX74377.1 - 4.1e-06 26.4 11.1 3 7.8 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF775 PF05603.7 EPX74378.1 - 8.3e-58 195.2 0.1 1e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) IGPD PF00475.13 EPX74379.1 - 4.8e-60 201.6 0.2 6.3e-60 201.2 0.1 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase adh_short PF00106.20 EPX74380.1 - 3.2e-15 56.4 0.0 5.8e-15 55.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPX74380.1 - 7.1e-07 29.2 0.0 8.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPX74380.1 - 0.00027 20.4 0.0 0.00046 19.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EPX74380.1 - 0.00041 20.0 0.1 0.0032 17.1 0.1 1.9 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EPX74380.1 - 0.00056 18.6 0.0 0.00099 17.8 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EPX74380.1 - 0.0014 17.6 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPX74380.1 - 0.0084 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF2433 PF10360.4 EPX74382.1 - 1.3e-39 135.5 0.5 2.8e-39 134.4 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.23 EPX74382.1 - 0.011 15.2 0.0 0.056 12.8 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase PRMT5 PF05185.11 EPX74383.1 - 1.7e-158 528.2 0.0 2.1e-158 527.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 EPX74384.1 - 2.4e-25 88.5 0.0 6.4e-25 87.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPX74384.1 - 3.6e-25 87.9 0.0 9e-25 86.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPX74384.1 - 8.2e-12 44.8 0.0 1.7e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPX74384.1 - 1.7e-08 34.1 0.0 4.2e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPX74384.1 - 2.2e-07 31.0 0.1 2.5e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.17 EPX74384.1 - 9e-05 21.9 0.0 0.00045 19.7 0.0 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EPX74384.1 - 0.00021 21.1 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_23 PF13476.1 EPX74384.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EPX74384.1 - 0.014 14.2 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EPX74384.1 - 0.025 14.4 0.6 3.1 7.6 0.1 2.7 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.9 EPX74384.1 - 0.036 13.8 0.1 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Response_reg PF00072.19 EPX74384.1 - 0.038 13.9 0.2 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 Response regulator receiver domain PhoH PF02562.11 EPX74384.1 - 0.072 12.3 0.0 0.44 9.7 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Glyco_transf_15 PF01793.11 EPX74385.1 - 8e-131 435.8 9.2 1e-130 435.5 6.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase ABC_tran PF00005.22 EPX74386.1 - 5.1e-46 156.3 0.0 6.2e-23 81.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EPX74386.1 - 1.1e-19 71.5 4.7 0.00065 19.7 0.1 4.5 3 1 1 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EPX74386.1 - 7.6e-19 67.3 2.9 7.6e-19 67.3 2.0 2.9 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 EPX74386.1 - 5e-10 38.7 0.1 0.00042 19.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EPX74386.1 - 4.3e-09 35.9 2.0 0.0019 17.4 0.3 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPX74386.1 - 3.5e-08 34.0 12.9 0.0004 20.7 0.4 4.2 4 1 0 4 4 4 2 AAA domain Miro PF08477.8 EPX74386.1 - 1e-07 32.4 0.0 0.014 15.8 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EPX74386.1 - 6e-07 30.3 0.3 0.039 14.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EPX74386.1 - 9.6e-07 28.9 0.1 0.07 13.2 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_15 PF13175.1 EPX74386.1 - 1e-06 28.1 4.9 0.14 11.1 0.0 4.7 3 1 0 4 4 4 2 AAA ATPase domain Dynamin_N PF00350.18 EPX74386.1 - 5.9e-06 26.2 4.0 0.11 12.3 0.2 3.9 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.18 EPX74386.1 - 6.3e-06 26.1 0.0 0.0073 16.2 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPX74386.1 - 1.5e-05 24.2 0.0 0.016 14.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EPX74386.1 - 2e-05 24.1 0.0 0.19 11.1 0.0 2.7 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_18 PF13238.1 EPX74386.1 - 5e-05 23.6 4.5 0.18 12.0 0.1 3.5 3 1 0 3 3 3 2 AAA domain NACHT PF05729.7 EPX74386.1 - 0.00015 21.4 1.2 0.64 9.6 0.0 2.7 3 0 0 3 3 2 2 NACHT domain MobB PF03205.9 EPX74386.1 - 0.00018 21.2 0.0 0.16 11.6 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EPX74386.1 - 0.00023 21.2 0.3 0.64 9.9 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 EPX74386.1 - 0.00038 20.0 0.4 0.43 9.9 0.1 2.9 3 0 0 3 3 3 1 AAA-like domain DUF87 PF01935.12 EPX74386.1 - 0.00054 19.8 3.3 0.73 9.6 0.0 3.5 2 1 1 3 3 3 1 Domain of unknown function DUF87 AAA_28 PF13521.1 EPX74386.1 - 0.00059 19.8 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EPX74386.1 - 0.00074 19.6 0.1 2.1 8.5 0.0 2.8 3 0 0 3 3 2 2 RNA helicase AAA_25 PF13481.1 EPX74386.1 - 0.0013 18.1 0.1 2 7.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EPX74386.1 - 0.0018 18.1 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPX74386.1 - 0.0024 17.5 0.1 2.5 7.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Septin PF00735.13 EPX74386.1 - 0.0045 16.0 0.1 1.6 7.7 0.0 2.5 2 0 0 2 2 2 1 Septin FeoB_N PF02421.13 EPX74386.1 - 0.0058 15.9 0.0 0.08 12.2 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B SbcCD_C PF13558.1 EPX74386.1 - 0.0064 16.3 0.3 3.5 7.6 0.0 3.4 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EPX74386.1 - 0.0075 15.0 0.0 1.1 8.0 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA PF00004.24 EPX74386.1 - 0.0088 16.2 0.1 2.5 8.3 0.0 3.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EPX74386.1 - 0.011 15.3 0.6 2.6 7.5 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 EPX74386.1 - 0.016 14.7 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EPX74386.1 - 0.024 13.5 0.1 7 5.4 0.0 2.7 2 1 0 2 2 2 0 NB-ARC domain DAP3 PF10236.4 EPX74386.1 - 0.04 12.8 0.6 6.5 5.5 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 EPX74386.1 - 0.048 12.5 0.0 2.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Pox_A32 PF04665.7 EPX74386.1 - 0.056 12.7 1.9 9.5 5.4 0.2 2.9 2 1 0 2 2 2 0 Poxvirus A32 protein KaiC PF06745.8 EPX74386.1 - 0.057 12.5 0.1 5.9 5.9 0.0 3.0 3 0 0 3 3 3 0 KaiC DUF2730 PF10805.3 EPX74386.1 - 0.061 13.0 0.3 0.28 10.9 0.1 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF2730) ATP-synt_ab PF00006.20 EPX74386.1 - 0.098 12.1 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 EPX74386.1 - 0.16 11.7 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_13 PF13166.1 EPX74386.1 - 8.8 4.6 11.4 1.5 7.1 0.0 3.5 3 1 1 4 4 4 0 AAA domain Metallophos PF00149.23 EPX74387.1 - 7.4e-39 133.2 0.9 1.1e-38 132.6 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UCR_TM PF02921.9 EPX74388.1 - 3.8e-19 68.6 4.7 7.7e-19 67.6 0.5 2.3 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EPX74388.1 - 4.2e-17 61.5 0.1 8.8e-17 60.4 0.0 1.6 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain PsaN PF05479.6 EPX74388.1 - 2.8 7.9 4.8 9.6 6.1 0.2 2.2 1 1 1 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) DUF3807 PF12720.2 EPX74389.1 - 1.8e-24 86.8 0.0 2.2e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) GEMIN8 PF15348.1 EPX74389.1 - 1.2e-07 31.9 0.6 1.8e-07 31.4 0.4 1.3 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 APC_CDC26 PF10471.4 EPX74389.1 - 0.23 12.2 1.5 1.8 9.3 0.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Coiled-coil_56 PF09813.4 EPX74389.1 - 0.35 10.8 2.3 3.3 7.7 0.2 2.7 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 56 Pro_isomerase PF00160.16 EPX74390.1 - 9.2e-41 139.6 0.0 1.9e-40 138.5 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Mnd1 PF03962.10 EPX74390.1 - 2.2 7.9 10.0 0.17 11.5 2.5 2.2 2 0 0 2 2 2 0 Mnd1 family DUF720 PF05302.6 EPX74390.1 - 3.3 7.4 7.2 5.1 6.8 4.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF720) Pho88 PF10032.4 EPX74391.1 - 6.6e-58 195.0 0.4 7.4e-58 194.9 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4042 PF13251.1 EPX74391.1 - 0.093 12.1 0.2 0.28 10.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) ThiF PF00899.16 EPX74392.1 - 2.7e-38 130.8 0.1 5.6e-38 129.8 0.1 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EPX74392.1 - 1.1e-30 105.0 0.5 2.1e-30 104.0 0.4 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EPX74392.1 - 5.6e-21 73.6 1.9 1.2e-20 72.5 1.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EPX74392.1 - 3.9e-07 30.0 0.2 8.7e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 EPX74392.1 - 2.6e-05 24.3 0.0 6.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EPX74392.1 - 0.00091 19.4 0.1 0.011 15.9 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding Polysacc_synt_2 PF02719.10 EPX74392.1 - 0.012 14.5 0.3 0.043 12.7 0.0 2.0 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein DivIC PF04977.10 EPX74392.1 - 0.49 9.9 5.0 12 5.4 1.7 2.6 2 0 0 2 2 2 0 Septum formation initiator PFK PF00365.15 EPX74393.1 - 1.5e-166 552.4 6.9 1.8e-120 401.2 2.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase Glyoxalase_2 PF12681.2 EPX74393.1 - 0.0003 21.3 0.0 0.00095 19.7 0.0 1.9 1 0 0 1 1 1 1 Glyoxalase-like domain DNA_pol_delta_4 PF04081.8 EPX74394.1 - 1.5e-38 131.9 0.2 2.4e-38 131.1 0.1 1.3 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Sad1_UNC PF07738.8 EPX74395.1 - 2.4e-37 127.7 0.1 4.5e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal UVR PF02151.14 EPX74395.1 - 3.1 7.4 5.8 0.32 10.5 0.8 1.8 2 0 0 2 2 2 0 UvrB/uvrC motif Cpn60_TCP1 PF00118.19 EPX74396.1 - 7.7e-142 473.3 11.8 8.8e-142 473.1 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.20 EPX74397.1 - 5e-66 222.5 0.0 2e-65 220.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74397.1 - 2.9e-37 128.1 0.0 6.1e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EPX74397.1 - 1.5e-27 95.0 19.0 1.2e-16 60.1 3.3 3.3 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 EPX74397.1 - 1.5e-20 72.6 30.2 1.5e-10 40.6 7.7 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EPX74397.1 - 1e-13 51.5 1.2 3.8e-13 49.7 0.9 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPX74397.1 - 0.0001 21.3 0.0 0.00019 20.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Prok-RING_1 PF14446.1 EPX74397.1 - 0.00074 19.1 5.7 0.00074 19.1 4.0 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Uds1 PF15456.1 EPX74397.1 - 1.6 8.7 17.3 0.068 13.1 1.6 3.8 3 1 0 3 3 3 0 Up-regulated During Septation HORMA PF02301.13 EPX74398.1 - 2.2e-23 82.8 0.3 3e-23 82.4 0.2 1.2 1 0 0 1 1 1 1 HORMA domain DEAD PF00270.24 EPX74399.1 - 3.6e-47 159.9 0.0 1.4e-45 154.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX74399.1 - 7.6e-26 89.7 0.1 1.6e-25 88.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 EPX74399.1 - 0.0059 16.9 3.5 0.017 15.4 2.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) ResIII PF04851.10 EPX74399.1 - 0.013 15.3 0.0 0.048 13.4 0.0 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PRAI PF00697.17 EPX74399.1 - 0.02 14.4 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Mito_carr PF00153.22 EPX74400.1 - 3.8e-71 234.8 3.6 1.3e-23 82.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cyclin_N PF00134.18 EPX74401.1 - 1.9e-12 46.8 1.5 1.8e-11 43.6 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPX74401.1 - 0.00044 20.1 0.7 0.097 12.6 0.0 2.7 2 1 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 EPX74401.1 - 0.00071 19.3 0.2 0.0017 18.1 0.1 1.6 1 0 0 1 1 1 1 Transcription factor TFIIB repeat NHase_beta PF02211.10 EPX74401.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Nitrile hydratase beta subunit Thioredoxin PF00085.15 EPX74402.1 - 7.6e-25 86.6 0.0 9.8e-25 86.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EPX74402.1 - 9.8e-08 32.0 0.1 4.6e-07 29.8 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EPX74402.1 - 7.1e-07 29.4 0.1 1.1e-05 25.6 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EPX74402.1 - 5.6e-05 22.7 0.0 7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EPX74402.1 - 0.00012 21.7 0.1 0.00015 21.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPX74402.1 - 0.00028 20.4 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 EPX74402.1 - 0.0047 16.9 0.1 0.0086 16.0 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.11 EPX74402.1 - 0.053 13.0 0.0 0.064 12.7 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Transket_pyr PF02779.19 EPX74404.1 - 1.3e-64 216.9 0.0 3.1e-64 215.7 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EPX74404.1 - 7.6e-57 192.2 0.0 1.1e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Sulfate_transp PF00916.15 EPX74405.1 - 1.5e-78 263.6 7.7 2.6e-78 262.8 5.4 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EPX74405.1 - 3.4e-32 109.9 3.0 3.4e-32 109.9 2.1 3.1 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EPX74405.1 - 4.4e-13 48.6 0.0 8.8e-13 47.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain WD40 PF00400.27 EPX74406.1 - 1.2e-06 28.1 0.5 0.0087 15.9 0.1 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat CNH PF00780.17 EPX74406.1 - 0.018 14.4 0.4 0.11 11.9 0.0 2.1 1 1 0 2 2 2 0 CNH domain Cyclin_N PF00134.18 EPX74407.1 - 3e-09 36.5 0.1 5.2e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPX74407.1 - 1.5 8.7 5.6 4.4 7.2 0.1 2.4 2 1 0 2 2 2 0 Cyclin, C-terminal domain FAT PF02259.18 EPX74408.1 - 8.5e-66 222.3 7.9 8.5e-66 222.3 5.5 2.4 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EPX74408.1 - 3e-21 75.9 0.1 9.3e-21 74.3 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EPX74408.1 - 3.2e-06 26.4 0.5 7.3e-06 25.3 0.3 1.7 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.12 EPX74408.1 - 0.022 14.6 1.6 9.1 6.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPX74408.1 - 0.042 13.7 2.1 5.1 7.1 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPX74408.1 - 0.57 9.8 4.1 12 5.6 0.3 3.0 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 EPX74408.1 - 1.2 10.0 4.6 59 4.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat UQ_con PF00179.21 EPX74409.1 - 1.3e-49 167.2 0.0 1.5e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ank_5 PF13857.1 EPX74410.1 - 1.5e-17 63.1 2.9 5.2e-10 39.2 0.6 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPX74410.1 - 2.3e-17 63.0 1.4 1.2e-10 41.5 0.6 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPX74410.1 - 2.6e-17 62.8 6.0 2.1e-06 28.0 0.2 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EPX74410.1 - 1.9e-14 52.6 5.3 1.1e-10 40.7 0.7 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EPX74410.1 - 1.7e-12 46.2 2.6 4e-08 32.7 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat AvrRpt-cleavage PF05627.6 EPX74410.1 - 0.091 11.8 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr RRM_1 PF00076.17 EPX74411.1 - 6.5e-13 48.1 1.5 2.1e-12 46.4 0.1 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74411.1 - 3.4e-10 39.7 0.4 1e-08 34.9 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74411.1 - 3.7e-08 33.0 0.6 1.1e-07 31.5 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2772 PF10970.3 EPX74411.1 - 0.12 12.3 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2772) Adap_comp_sub PF00928.16 EPX74412.1 - 6.9e-92 307.2 0.0 8.5e-92 306.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EPX74412.1 - 4.1e-07 29.8 0.5 6.7e-07 29.1 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.9 EPX74412.1 - 6.1e-05 21.7 0.0 8.2e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 FMO-like PF00743.14 EPX74413.1 - 1e-34 119.6 0.0 1.8e-20 72.6 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EPX74413.1 - 5.5e-17 62.5 0.0 1.3e-16 61.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPX74413.1 - 1.5e-14 54.0 0.0 6.2e-13 48.7 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPX74413.1 - 5.2e-08 32.1 0.2 9.5e-06 24.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPX74413.1 - 1.4e-06 28.3 0.0 8e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPX74413.1 - 3.8e-06 26.8 0.0 8.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPX74413.1 - 0.00038 19.6 0.1 0.00059 19.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EPX74413.1 - 0.00043 19.3 0.0 0.011 14.6 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPX74413.1 - 0.017 13.5 0.1 0.025 13.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EPX74413.1 - 0.22 10.5 0.0 0.47 9.4 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Hap4_Hap_bind PF10297.4 EPX74414.1 - 3e-07 30.0 9.7 3e-07 30.0 6.8 3.0 3 0 0 3 3 3 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 TPR_MLP1_2 PF07926.7 EPX74414.1 - 0.014 15.1 1.0 0.029 14.1 0.7 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4570 PF15134.1 EPX74414.1 - 0.024 14.4 1.7 0.063 13.1 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF2353 PF09789.4 EPX74414.1 - 0.033 13.4 0.2 0.05 12.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF3338 PF11819.3 EPX74414.1 - 0.057 12.8 0.6 0.11 11.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) bZIP_2 PF07716.10 EPX74414.1 - 0.95 9.3 5.6 3 7.7 3.9 1.8 1 0 0 1 1 1 0 Basic region leucine zipper CUE PF02845.11 EPX74415.1 - 1.6e-11 43.4 0.0 1.3e-10 40.5 0.0 2.3 2 0 0 2 2 2 1 CUE domain Coa1 PF08695.5 EPX74416.1 - 8.8e-28 96.1 0.0 1.3e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Integrin_alpha2 PF08441.7 EPX74417.1 - 0.045 12.6 0.0 0.06 12.1 0.0 1.1 1 0 0 1 1 1 0 Integrin alpha DUF2372 PF10178.4 EPX74417.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) RRM_1 PF00076.17 EPX74418.1 - 4.5e-17 61.4 0.0 1.4e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74418.1 - 1.7e-14 53.4 0.0 4.5e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74418.1 - 0.00013 21.7 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DivIC PF04977.10 EPX74418.1 - 0.0037 16.7 5.8 0.0051 16.2 4.1 1.2 1 0 0 1 1 1 1 Septum formation initiator APG6 PF04111.7 EPX74418.1 - 0.0086 15.1 1.1 0.0093 15.0 0.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 WEMBL PF05701.6 EPX74418.1 - 0.0098 14.3 3.7 0.011 14.2 2.6 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Flagellin_C PF00700.16 EPX74418.1 - 0.012 15.7 0.3 0.017 15.2 0.2 1.3 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region GAS PF13851.1 EPX74418.1 - 0.021 14.0 3.2 0.027 13.6 2.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CASP_C PF08172.7 EPX74418.1 - 0.025 13.6 0.1 0.031 13.3 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal Striatin PF08232.7 EPX74418.1 - 0.029 14.6 1.6 0.036 14.3 1.1 1.1 1 0 0 1 1 1 0 Striatin family PEARLI-4 PF05278.7 EPX74418.1 - 0.048 13.0 2.2 0.057 12.7 1.5 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Talin_middle PF09141.5 EPX74418.1 - 0.059 13.0 0.4 0.07 12.8 0.3 1.1 1 0 0 1 1 1 0 Talin, middle domain UPF0242 PF06785.6 EPX74418.1 - 0.089 11.4 3.1 0.12 11.0 2.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) BLOC1_2 PF10046.4 EPX74418.1 - 0.11 12.6 1.2 0.14 12.2 0.9 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.14 EPX74418.1 - 0.14 9.9 0.8 0.15 9.8 0.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EPX74418.1 - 0.16 12.3 2.0 0.21 11.9 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 EPX74418.1 - 0.2 12.1 3.2 0.32 11.4 2.2 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF724 PF05266.9 EPX74418.1 - 0.2 11.2 5.0 0.25 10.9 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DASH_Dam1 PF08653.5 EPX74418.1 - 0.25 11.1 0.9 0.39 10.5 0.6 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 DUF2630 PF10944.3 EPX74418.1 - 0.25 11.4 5.6 0.38 10.8 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Ax_dynein_light PF10211.4 EPX74418.1 - 0.4 10.4 4.4 0.49 10.2 3.1 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain IncA PF04156.9 EPX74418.1 - 0.85 9.1 2.9 0.96 9.0 2.0 1.1 1 0 0 1 1 1 0 IncA protein DUF4337 PF14235.1 EPX74418.1 - 1.1 9.0 5.2 1.4 8.7 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HECT PF00632.20 EPX74419.1 - 2e-93 313.0 0.0 3e-93 312.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EPX74419.1 - 4.1e-33 112.8 20.1 2.6e-11 43.1 1.4 3.9 4 0 0 4 4 4 3 WW domain C2 PF00168.25 EPX74419.1 - 2e-13 49.9 0.0 5e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain AAA PF00004.24 EPX74420.1 - 1.8e-91 303.1 0.0 2.6e-46 157.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPX74420.1 - 3.5e-15 55.6 0.0 8.9e-08 31.4 0.0 3.1 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EPX74420.1 - 5.1e-13 49.9 0.0 1.9e-07 31.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPX74420.1 - 5.3e-13 49.3 5.8 7.2e-05 22.8 0.1 5.4 4 2 2 6 6 4 2 AAA ATPase domain AAA_5 PF07728.9 EPX74420.1 - 2.5e-12 46.7 0.2 0.00018 21.2 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPX74420.1 - 7.3e-12 45.5 0.1 0.0032 17.6 0.0 5.0 3 3 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EPX74420.1 - 1.1e-11 44.7 0.0 2.7e-05 24.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPX74420.1 - 8.5e-11 42.2 0.0 1.7e-06 28.3 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_2 PF07724.9 EPX74420.1 - 3.8e-10 39.9 0.0 0.0014 18.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EPX74420.1 - 4.3e-10 39.5 0.0 0.0014 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EPX74420.1 - 1.7e-09 37.8 0.0 0.0019 18.3 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Zeta_toxin PF06414.7 EPX74420.1 - 2.6e-09 36.4 0.0 0.0021 17.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EPX74420.1 - 5.5e-09 35.2 0.0 0.00014 20.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EPX74420.1 - 4.4e-08 32.7 0.9 0.0078 15.9 0.1 3.7 3 1 0 3 3 2 2 Part of AAA domain AAA_28 PF13521.1 EPX74420.1 - 5.4e-08 32.9 0.0 0.0017 18.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EPX74420.1 - 5.4e-08 32.4 0.0 0.0056 16.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_3 PF07726.6 EPX74420.1 - 7e-08 32.1 0.0 0.0012 18.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EPX74420.1 - 1.3e-07 31.0 0.5 0.0063 15.7 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EPX74420.1 - 1.3e-07 31.3 0.3 0.009 15.6 0.0 3.6 3 1 1 4 4 3 2 NACHT domain AAA_25 PF13481.1 EPX74420.1 - 2e-07 30.5 5.4 0.088 12.1 0.0 4.7 2 2 1 4 4 4 2 AAA domain Cytidylate_kin2 PF13189.1 EPX74420.1 - 1.6e-06 28.1 0.0 0.00097 19.0 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family Vps4_C PF09336.5 EPX74420.1 - 5.4e-06 26.2 2.9 0.00041 20.1 0.0 3.9 3 1 0 3 3 3 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.22 EPX74420.1 - 6.6e-06 26.4 0.0 0.28 11.4 0.0 3.3 3 0 0 3 3 2 2 ABC transporter SKI PF01202.17 EPX74420.1 - 4e-05 23.5 1.8 0.18 11.6 0.0 3.7 4 0 0 4 4 3 2 Shikimate kinase Sigma54_activat PF00158.21 EPX74420.1 - 4.4e-05 23.0 0.0 0.24 10.8 0.0 3.5 3 1 0 3 3 3 2 Sigma-54 interaction domain KaiC PF06745.8 EPX74420.1 - 5.2e-05 22.4 0.1 0.21 10.6 0.0 3.2 3 0 0 3 3 3 1 KaiC Sigma54_activ_2 PF14532.1 EPX74420.1 - 7.2e-05 22.8 0.0 0.42 10.6 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain ATP-synt_ab PF00006.20 EPX74420.1 - 0.00015 21.3 0.0 0.45 9.9 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 EPX74420.1 - 0.00017 20.5 0.0 0.026 13.4 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 EPX74420.1 - 0.00024 20.7 0.7 0.95 8.9 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EPX74420.1 - 0.00034 19.8 0.2 0.58 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.17 EPX74420.1 - 0.00035 19.5 0.0 0.36 9.6 0.0 2.7 3 0 0 3 3 2 2 NB-ARC domain Rad17 PF03215.10 EPX74420.1 - 0.0007 18.4 0.0 0.2 10.3 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EPX74420.1 - 0.00082 19.1 0.0 1.3 8.6 0.0 3.0 2 1 1 3 3 3 1 Archaeal ATPase Parvo_NS1 PF01057.12 EPX74420.1 - 0.00094 18.1 0.1 1.1 8.0 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EPX74420.1 - 0.0011 18.5 0.0 0.44 10.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AFG1_ATPase PF03969.11 EPX74420.1 - 0.0018 17.1 0.1 0.38 9.4 0.0 3.0 4 0 0 4 4 4 1 AFG1-like ATPase AAA_24 PF13479.1 EPX74420.1 - 0.0023 17.5 0.0 1.6 8.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EPX74420.1 - 0.0038 17.0 1.1 3.6 7.3 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit SRPRB PF09439.5 EPX74420.1 - 0.0094 15.1 0.0 3.2 6.9 0.0 2.9 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 EPX74420.1 - 0.01 15.5 0.0 2.5 7.7 0.0 3.0 3 0 0 3 3 2 0 NTPase CPT PF07931.7 EPX74420.1 - 0.011 15.4 0.0 0.3 10.7 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_10 PF12846.2 EPX74420.1 - 0.022 14.2 0.2 10 5.4 0.0 3.4 3 1 0 3 3 3 0 AAA-like domain Guanylate_kin PF00625.16 EPX74420.1 - 0.033 13.6 0.1 7.8 5.8 0.0 3.9 3 2 1 4 4 4 0 Guanylate kinase PduV-EutP PF10662.4 EPX74420.1 - 0.046 13.1 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.4 EPX74420.1 - 0.054 12.4 1.4 2.4 7.0 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.13 EPX74420.1 - 0.07 12.7 0.0 3 7.4 0.0 2.7 3 1 0 3 3 2 0 Bacterial dnaA protein ADK PF00406.17 EPX74420.1 - 0.098 12.5 0.1 13 5.6 0.0 2.8 3 0 0 3 3 2 0 Adenylate kinase IPT PF01745.11 EPX74420.1 - 0.11 11.6 0.1 12 5.0 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase EMP24_GP25L PF01105.19 EPX74421.1 - 6.4e-36 123.7 1.4 7.3e-36 123.5 1.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Glyco_transf_5 PF08323.6 EPX74422.1 - 0.069 12.6 0.1 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Oxidored_q1 PF00361.15 EPX74423.1 - 0.0037 16.5 2.0 0.0037 16.5 1.4 2.0 2 0 0 2 2 2 1 NADH-Ubiquinone/plastoquinone (complex I), various chains ATP_synt_I PF03899.10 EPX74423.1 - 0.23 11.6 11.7 0.14 12.3 1.1 3.1 2 1 1 3 3 3 0 ATP synthase I chain Pkinase PF00069.20 EPX74424.1 - 2.8e-58 197.1 0.0 4.2e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74424.1 - 4e-36 124.4 0.0 1.1e-35 122.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX74424.1 - 0.0027 16.6 0.0 0.0078 15.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Tho2 PF11262.3 EPX74425.1 - 5.6e-80 268.5 2.8 1.4e-79 267.2 2.0 1.7 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EPX74425.1 - 4.2e-28 96.9 0.0 1.3e-27 95.3 0.0 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit PAM2 PF07145.10 EPX74425.1 - 0.01 15.2 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Hamartin PF04388.7 EPX74426.1 - 3.3e-84 283.8 23.3 2.4e-64 218.2 0.1 2.2 1 1 1 2 2 2 2 Hamartin protein RGS PF00615.14 EPX74427.1 - 2.8e-18 66.1 0.8 8.2e-18 64.6 0.2 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 EPX74427.1 - 3.3e-05 23.5 1.6 0.00074 19.2 0.0 3.3 4 0 0 4 4 4 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) zf-C2H2_jaz PF12171.3 EPX74428.1 - 1.6e-06 28.0 0.1 1.6e-06 28.0 0.1 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPX74428.1 - 0.00027 21.0 0.9 0.00047 20.2 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 EPX74428.1 - 0.0011 18.5 0.1 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_2 PF12756.2 EPX74428.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF1777 PF08648.7 EPX74428.1 - 1 9.0 8.0 0.086 12.5 2.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Exonuc_VII_L PF02601.10 EPX74428.1 - 1.7 7.7 5.6 2.2 7.4 3.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4259 PF14078.1 EPX74428.1 - 8 6.9 6.9 4.2 7.8 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4259) GCS PF03074.11 EPX74429.1 - 3.8e-163 542.8 0.0 5.2e-163 542.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase Ank PF00023.25 EPX74430.1 - 7e-18 63.4 1.0 4.9e-08 32.3 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EPX74430.1 - 4e-16 59.1 0.4 2.3e-07 31.0 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPX74430.1 - 1.5e-15 56.8 1.6 3.1e-07 30.4 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPX74430.1 - 1.7e-15 55.5 1.1 1.6e-06 27.7 0.1 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EPX74430.1 - 5.1e-14 52.3 3.0 3.1e-06 27.5 0.1 5.0 2 1 3 5 5 5 3 Ankyrin repeats (many copies) KilA-N PF04383.8 EPX74430.1 - 6.9e-05 22.4 0.2 0.00047 19.7 0.1 2.2 1 1 0 1 1 1 1 KilA-N domain DEAD PF00270.24 EPX74431.1 - 2.9e-39 134.2 0.0 9e-39 132.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX74431.1 - 1.3e-28 98.6 0.0 4.7e-28 96.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX74431.1 - 4.8e-10 39.5 0.0 1.2e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPX74431.1 - 2.8e-09 36.2 0.0 2.8e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF2075 PF09848.4 EPX74431.1 - 0.023 13.7 0.4 0.044 12.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EPX74431.1 - 0.032 14.3 0.6 0.21 11.7 0.2 2.5 1 1 1 2 2 2 0 AAA domain ATP-synt_G PF04718.10 EPX74432.1 - 6.8e-10 39.5 0.7 2.1e-09 37.9 0.5 1.8 1 1 0 1 1 1 1 Mitochondrial ATP synthase g subunit YqeY PF09424.5 EPX74433.1 - 4.8e-20 71.8 5.3 5.5e-20 71.6 3.7 1.0 1 0 0 1 1 1 1 Yqey-like protein Pox_A3L PF05288.6 EPX74433.1 - 0.029 14.0 5.3 0.046 13.4 0.2 2.7 1 1 2 3 3 3 0 Poxvirus A3L Protein RhoGEF PF00621.15 EPX74433.1 - 0.056 13.3 1.3 0.069 13.0 0.9 1.1 1 0 0 1 1 1 0 RhoGEF domain BSP PF04450.7 EPX74433.1 - 0.061 12.7 0.1 0.077 12.4 0.1 1.1 1 0 0 1 1 1 0 Peptidase of plants and bacteria Activator-TraM PF11657.3 EPX74433.1 - 0.13 11.6 2.8 0.17 11.3 1.9 1.1 1 0 0 1 1 1 0 Transcriptional activator TraM DNA_pol_B_3 PF08408.5 EPX74433.1 - 0.17 11.7 1.6 0.21 11.4 1.1 1.1 1 0 0 1 1 1 0 DNA polymerase family B viral insert ING PF12998.2 EPX74433.1 - 0.37 11.0 4.9 5.1 7.4 0.3 2.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Lon_C PF05362.8 EPX74434.1 - 1.3e-60 204.1 0.0 2.7e-60 203.2 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EPX74434.1 - 1.9e-37 128.9 0.8 5.2e-37 127.5 0.6 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EPX74434.1 - 7.9e-24 84.3 0.3 2.4e-23 82.7 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPX74434.1 - 2.3e-10 40.3 0.0 8.7e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EPX74434.1 - 4.8e-06 26.0 0.0 1.1e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 EPX74434.1 - 1.7e-05 24.9 2.1 0.00019 21.5 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPX74434.1 - 7.6e-05 23.5 0.0 0.00031 21.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPX74434.1 - 8.2e-05 22.6 0.2 0.00044 20.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EPX74434.1 - 0.00048 20.0 0.0 0.003 17.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.6 EPX74434.1 - 0.00075 18.2 0.0 0.0014 17.4 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.7 EPX74434.1 - 0.001 18.1 0.1 0.0047 15.9 0.0 2.2 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EPX74434.1 - 0.0014 18.7 0.0 0.0037 17.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EPX74434.1 - 0.0019 18.5 1.6 0.0045 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EPX74434.1 - 0.015 14.9 0.0 0.039 13.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EPX74434.1 - 0.016 14.9 0.6 0.53 9.9 0.0 2.9 2 1 1 3 3 3 0 NTPase DUF258 PF03193.11 EPX74434.1 - 0.021 14.0 0.5 0.093 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SKI PF01202.17 EPX74434.1 - 0.035 13.9 2.0 0.042 13.7 0.0 2.3 2 0 0 2 2 1 0 Shikimate kinase AAA_25 PF13481.1 EPX74434.1 - 0.035 13.4 0.2 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EPX74434.1 - 0.044 13.2 0.0 0.097 12.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EPX74434.1 - 0.077 12.6 0.1 0.5 10.0 0.1 2.2 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 EPX74434.1 - 0.14 11.9 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 EPX74434.1 - 0.18 11.7 3.8 2.1 8.2 0.0 3.6 2 1 1 3 3 3 0 AAA domain Arf PF00025.16 EPX74435.1 - 1.5e-31 109.0 0.4 3.7e-31 107.6 0.2 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 EPX74435.1 - 0.00097 18.5 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 EPX74435.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EPX74435.1 - 0.0025 17.0 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NACHT PF05729.7 EPX74435.1 - 0.024 14.2 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AMP-binding PF00501.23 EPX74436.1 - 6.1e-28 97.3 0.0 2.3e-15 55.8 0.0 4.1 4 0 0 4 4 4 4 AMP-binding enzyme Sterol_MT_C PF08498.5 EPX74437.1 - 1.6e-27 95.2 0.2 2.4e-27 94.6 0.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EPX74437.1 - 1.6e-20 73.4 0.0 3.4e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX74437.1 - 2.8e-15 56.3 0.0 5.7e-15 55.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX74437.1 - 2.9e-13 49.6 0.0 4.8e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX74437.1 - 5.8e-10 39.4 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX74437.1 - 1.1e-09 38.6 0.1 6e-09 36.2 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPX74437.1 - 5.3e-09 35.5 0.0 9.2e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EPX74437.1 - 1.9e-08 34.8 0.0 1.2e-07 32.3 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain CMAS PF02353.15 EPX74437.1 - 3.3e-08 32.9 0.1 4.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EPX74437.1 - 1.2e-07 31.7 0.0 2.8e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EPX74437.1 - 8.9e-05 21.9 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.11 EPX74437.1 - 0.0016 16.8 0.0 0.0021 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.10 EPX74437.1 - 0.0084 15.7 0.0 0.026 14.1 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase CDC48_2 PF02933.12 EPX74437.1 - 0.016 14.7 0.2 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 PCMT PF01135.14 EPX74437.1 - 0.023 14.2 0.1 0.71 9.3 0.1 2.2 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EPX74437.1 - 0.088 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain BolA PF01722.13 EPX74438.1 - 2.9e-26 91.2 0.8 3.8e-26 90.8 0.5 1.2 1 0 0 1 1 1 1 BolA-like protein DUF2508 PF10704.4 EPX74438.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2508) DUF1227 PF06777.6 EPX74439.1 - 3.3e-61 205.2 0.3 7.7e-61 204.0 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EPX74439.1 - 1.4e-52 177.6 0.5 2.4e-52 176.8 0.1 1.6 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.1 EPX74439.1 - 3.6e-43 147.4 0.0 9.4e-43 146.0 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_11 PF13086.1 EPX74439.1 - 0.00049 19.7 0.0 0.0012 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 EPX74439.1 - 0.0048 16.4 0.0 0.72 9.3 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EPX74439.1 - 0.012 14.4 0.1 0.13 11.0 0.0 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 EPX74439.1 - 0.027 14.3 0.0 0.85 9.4 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pkinase PF00069.20 EPX74440.1 - 2e-54 184.5 0.0 2.6e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74440.1 - 1.2e-18 67.1 0.0 1.8e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EPX74440.1 - 0.0022 16.8 0.6 0.0032 16.3 0.4 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Lactamase_B_2 PF12706.2 EPX74441.1 - 4.7e-32 111.0 0.0 1.1e-31 109.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EPX74441.1 - 1.9e-29 100.8 0.1 5.6e-29 99.3 0.0 1.9 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EPX74441.1 - 7.4e-07 29.0 0.0 2.9e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Rtf2 PF04641.7 EPX74442.1 - 1.9e-64 217.3 0.8 2.1e-64 217.2 0.5 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EPX74442.1 - 2.2e-07 30.2 0.4 0.00049 19.5 0.1 2.6 2 1 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EPX74442.1 - 1.9e-06 27.4 0.1 1.9e-06 27.4 0.1 2.3 3 0 0 3 3 3 1 RING-type zinc-finger Tap-RNA_bind PF09162.5 EPX74442.1 - 0.017 14.6 0.1 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Tap, RNA-binding zf-RING_2 PF13639.1 EPX74442.1 - 0.036 13.8 1.0 0.084 12.7 0.2 1.9 2 0 0 2 2 2 0 Ring finger domain TORC_M PF12885.2 EPX74442.1 - 0.071 12.8 2.1 5.8 6.6 0.4 2.3 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain CDP-OH_P_transf PF01066.16 EPX74443.1 - 3.8e-14 52.8 0.8 3.8e-14 52.8 0.6 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.20 EPX74444.1 - 4.2e-37 127.7 0.0 4.9e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74444.1 - 8.4e-24 84.0 0.0 1.1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX74444.1 - 0.00017 21.4 0.0 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPX74444.1 - 0.00037 19.5 0.0 0.00056 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EPX74444.1 - 0.028 13.7 0.1 0.067 12.5 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL MgtE_N PF03448.12 EPX74444.1 - 0.058 13.7 0.0 7.1 7.0 0.0 2.9 3 1 0 3 3 3 0 MgtE intracellular N domain Kdo PF06293.9 EPX74444.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EPX74444.1 - 0.17 10.9 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase EXS PF03124.9 EPX74445.1 - 1e-48 166.1 22.6 1.3e-48 165.8 15.7 1.1 1 0 0 1 1 1 1 EXS family Cpn60_TCP1 PF00118.19 EPX74446.1 - 5.7e-136 453.9 11.4 6.7e-136 453.7 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mon1 PF03164.9 EPX74447.1 - 1.2e-120 402.8 11.9 1.6e-120 402.5 8.2 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Hep_59 PF07052.6 EPX74448.1 - 1.5e-08 34.8 1.4 1.5e-08 34.8 0.9 2.7 3 1 1 4 4 4 1 Hepatocellular carcinoma-associated antigen 59 GRASP55_65 PF04495.9 EPX74449.1 - 5.1e-56 188.4 0.1 1.9e-47 160.7 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EPX74449.1 - 0.0061 16.4 0.0 0.045 13.6 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Peptidase_M3 PF01432.15 EPX74450.1 - 3.2e-135 451.6 0.0 4.1e-135 451.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 RhoGEF PF00621.15 EPX74450.1 - 0.0086 15.9 0.8 0.061 13.2 0.1 2.5 2 0 0 2 2 2 1 RhoGEF domain CwfJ_C_1 PF04677.10 EPX74451.1 - 7.7e-40 135.3 0.0 1.4e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EPX74451.1 - 1e-24 86.8 1.3 1.9e-24 85.9 0.9 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 IMPDH PF00478.20 EPX74451.1 - 0.25 10.2 0.0 0.39 9.5 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain IncA PF04156.9 EPX74453.1 - 3.6e-13 49.5 362.9 0.0027 17.3 9.6 18.3 2 2 16 19 19 19 12 IncA protein Myosin_tail_1 PF01576.14 EPX74453.1 - 2e-07 29.1 334.4 1.2e-05 23.3 45.0 7.4 2 2 3 6 6 6 3 Myosin tail CENP-F_leu_zip PF10473.4 EPX74453.1 - 0.00018 21.3 11.2 0.00018 21.3 7.8 22.1 3 2 18 22 22 22 8 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EPX74453.1 - 0.0021 17.3 4.1 0.0021 17.3 2.8 15.5 1 1 14 17 17 17 13 Reovirus sigma C capsid protein Laminin_II PF06009.7 EPX74453.1 - 0.0026 17.5 6.8 0.0026 17.5 4.7 19.8 4 3 16 21 21 21 2 Laminin Domain II BLOC1_2 PF10046.4 EPX74453.1 - 0.0032 17.5 9.9 0.0032 17.5 6.9 24.3 4 4 21 28 28 28 5 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 EPX74453.1 - 3.1 6.1 302.0 0.044 12.2 19.0 10.8 1 1 10 11 11 11 0 AAA domain VHS PF00790.14 EPX74454.1 - 1.8e-46 157.2 0.0 3.7e-46 156.2 0.0 1.5 1 0 0 1 1 1 1 VHS domain Alpha_adaptinC2 PF02883.15 EPX74454.1 - 1.5e-08 34.9 0.1 2.9e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 EPX74454.1 - 1.4e-05 25.0 1.7 0.00027 20.8 0.5 2.8 2 0 0 2 2 2 1 GAT domain MetRS-N PF09635.5 EPX74454.1 - 0.0047 17.3 0.8 0.012 15.9 0.6 1.7 1 0 0 1 1 1 1 MetRS-N binding domain DUF367 PF04034.8 EPX74455.1 - 5.2e-55 184.4 0.0 7.3e-55 183.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EPX74455.1 - 2.5e-12 46.1 0.1 4.5e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Lgl_C PF08596.5 EPX74456.1 - 2e-74 250.4 0.0 6.4e-73 245.4 0.0 2.2 1 1 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EPX74456.1 - 0.016 15.1 2.4 1.2 9.1 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Pkinase PF00069.20 EPX74457.1 - 3.6e-68 229.5 0.0 6.1e-68 228.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74457.1 - 1.8e-42 145.2 0.0 3.1e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX74457.1 - 4.6e-07 29.0 0.0 5.5e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Integrase_Zn PF02022.14 EPX74457.1 - 0.025 14.0 0.1 0.057 12.8 0.0 1.6 1 0 0 1 1 1 0 Integrase Zinc binding domain Kdo PF06293.9 EPX74457.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX74457.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DNA_pol_A_exo1 PF01612.15 EPX74458.1 - 1.7e-51 174.2 1.1 3.2e-51 173.2 0.4 1.8 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.7 EPX74458.1 - 4.1e-20 71.8 0.8 4.1e-20 71.8 0.5 3.4 5 0 0 5 5 5 1 PMC2NT (NUC016) domain HRDC PF00570.18 EPX74458.1 - 7.3e-15 54.4 0.0 2.1e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 HRDC domain CRAL_TRIO PF00650.15 EPX74459.1 - 5.7e-37 126.6 0.0 1.3e-36 125.5 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPX74459.1 - 2.1e-11 43.7 0.6 6e-11 42.3 0.4 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPX74459.1 - 1.8e-05 24.6 0.0 9.5e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain RRM_1 PF00076.17 EPX74460.1 - 6.9e-07 28.8 0.0 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74460.1 - 2.2e-05 24.1 0.1 3.9e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74460.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HopJ PF08888.6 EPX74460.1 - 0.042 13.8 0.3 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 HopJ type III effector protein Zn_clus PF00172.13 EPX74461.1 - 8.5e-09 35.1 14.4 1.9e-08 34.0 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin PF02996.12 EPX74462.1 - 2.2e-34 117.6 3.6 2.2e-34 117.6 2.5 1.8 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 EPX74462.1 - 0.002 17.8 7.5 0.0023 17.6 2.5 2.4 1 1 1 2 2 2 1 Prefoldin subunit THOC7 PF05615.8 EPX74462.1 - 0.17 12.1 5.3 0.14 12.4 0.6 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 DUF2098 PF09871.4 EPX74462.1 - 1 9.3 3.6 0.48 10.3 0.7 1.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) PAP2 PF01569.16 EPX74463.1 - 1.8e-10 40.5 11.0 1.8e-10 40.5 7.6 2.7 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EPX74463.1 - 3e-08 33.4 7.9 7.2e-08 32.1 5.4 1.6 1 1 0 1 1 1 1 PAP2 superfamily MMS1_N PF10433.4 EPX74464.1 - 1.4e-51 175.1 0.3 2.3e-51 174.4 0.2 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EPX74464.1 - 1.1e-18 67.4 0.0 2.2e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region DUF4210 PF13915.1 EPX74465.1 - 7.8e-14 51.7 0.1 1.9e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EPX74465.1 - 0.00023 20.9 0.1 0.00067 19.4 0.1 1.9 1 0 0 1 1 1 1 Chromosome segregation during meiosis Img2 PF05046.9 EPX74466.1 - 6.4e-21 74.3 0.0 7.5e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 EPX74466.1 - 0.0021 17.8 0.2 0.0033 17.1 0.1 1.3 1 1 0 1 1 1 1 Translation initiation factor SUI1 CRAL_TRIO PF00650.15 EPX74467.1 - 2.2e-46 157.2 0.0 4.4e-46 156.2 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPX74467.1 - 3.5e-14 52.6 0.3 1.7e-13 50.4 0.2 2.2 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPX74467.1 - 5.4e-13 49.1 0.0 1.4e-12 47.8 0.0 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain TPP_enzyme_N PF02776.13 EPX74468.1 - 1e-32 112.9 0.0 1.7e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPX74468.1 - 2.3e-28 98.6 0.0 5.9e-28 97.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EPX74468.1 - 3.1e-15 56.0 0.0 9.3e-15 54.5 0.0 1.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EPX74468.1 - 0.014 14.2 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Peptidase_M17 PF00883.16 EPX74469.1 - 1.7e-119 398.3 0.1 2.3e-119 397.9 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EPX74469.1 - 2e-06 27.5 0.0 4.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Transp_Tc5_C PF04236.10 EPX74469.1 - 0.26 11.5 1.5 3.2 8.0 0.1 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain UCH PF00443.24 EPX74470.1 - 1.3e-58 198.2 5.3 1.3e-58 198.2 3.6 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPX74470.1 - 1.8e-23 83.4 5.1 3.1e-23 82.6 3.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPX74470.1 - 1e-10 41.5 11.5 1e-10 41.5 8.0 3.2 5 0 0 5 5 5 1 Zn-finger in ubiquitin-hydrolases and other protein Mnd1 PF03962.10 EPX74471.1 - 3.4e-52 176.8 6.3 3.9e-52 176.6 4.4 1.0 1 0 0 1 1 1 1 Mnd1 family FUR PF01475.14 EPX74471.1 - 0.00077 19.3 0.2 0.0022 17.8 0.1 1.7 1 1 0 2 2 2 1 Ferric uptake regulator family Penicillinase_R PF03965.11 EPX74471.1 - 0.00084 19.4 0.9 0.0014 18.7 0.2 1.7 2 0 0 2 2 2 1 Penicillinase repressor TrmB PF01978.14 EPX74471.1 - 0.005 16.5 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Aldo_ket_red PF00248.16 EPX74471.1 - 0.011 14.6 0.3 0.022 13.5 0.2 1.6 1 1 0 1 1 1 0 Aldo/keto reductase family DUF3322 PF11795.3 EPX74471.1 - 0.021 14.4 0.3 0.042 13.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) TBPIP PF07106.8 EPX74471.1 - 0.023 14.2 8.3 0.017 14.6 4.5 1.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA PF00004.24 EPX74471.1 - 0.077 13.1 0.9 0.61 10.2 0.0 2.2 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) YebG PF07130.7 EPX74471.1 - 0.085 12.5 2.9 0.069 12.8 0.6 1.9 2 0 0 2 2 2 0 YebG protein MscS_porin PF12795.2 EPX74471.1 - 0.46 9.7 15.6 0.15 11.3 8.5 1.9 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF848 PF05852.6 EPX74471.1 - 0.65 9.8 12.3 0.11 12.3 1.9 2.8 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2802 PF10975.3 EPX74471.1 - 1.3 8.8 4.9 12 5.7 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2802) Spc24 PF08286.6 EPX74471.1 - 2.2 7.9 10.3 1.3 8.7 2.6 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FlxA PF14282.1 EPX74471.1 - 2.8 7.9 10.9 22 5.0 7.4 2.4 1 1 0 1 1 1 0 FlxA-like protein IncA PF04156.9 EPX74471.1 - 2.9 7.4 17.4 0.25 10.9 8.3 1.8 1 1 1 2 2 2 0 IncA protein p450 PF00067.17 EPX74472.1 - 1e-74 251.7 0.0 1.3e-74 251.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RhoGAP PF00620.22 EPX74473.1 - 2e-14 53.4 0.6 5.6e-14 52.0 0.1 2.1 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 EPX74473.1 - 1.2e-12 47.4 0.0 2.8e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.18 EPX74473.1 - 5e-11 42.6 1.5 5e-11 42.6 1.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Flagellin_N PF00669.15 EPX74473.1 - 0.15 11.8 2.1 0.38 10.5 0.1 2.6 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region RF-1 PF00472.15 EPX74474.1 - 5.7e-37 125.9 4.2 5.7e-37 125.9 2.9 1.8 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 EPX74474.1 - 4.9e-29 100.3 1.5 1e-28 99.3 0.1 2.2 2 0 0 2 2 2 1 PCRF domain DUF3523 PF12037.3 EPX74474.1 - 0.66 8.9 11.2 0.32 9.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) DUF1912 PF08930.5 EPX74474.1 - 1.2 9.2 3.9 0.74 9.9 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1912) PX PF00787.19 EPX74475.1 - 7.1e-27 93.4 0.7 3.1e-26 91.3 0.1 2.4 2 0 0 2 2 2 1 PX domain PLDc PF00614.17 EPX74475.1 - 1.5e-19 69.1 2.0 6e-10 38.5 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EPX74475.1 - 7.9e-11 41.7 0.1 4.5e-06 26.4 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain MRP-S28 PF10213.4 EPX74476.1 - 4.4e-32 110.8 0.4 6.9e-32 110.2 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein ECR1_N PF14382.1 EPX74477.1 - 1.2e-17 62.8 0.1 2.6e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EPX74477.1 - 0.00053 19.8 0.2 0.019 14.8 0.0 2.8 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 EPX74477.1 - 0.0047 16.9 0.4 1 9.4 0.0 3.8 4 0 0 4 4 4 1 S1 RNA binding domain tRNA-synt_1b PF00579.20 EPX74478.1 - 1.7e-23 83.1 0.0 3.6e-23 82.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) NIF PF03031.13 EPX74478.1 - 0.039 13.6 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase RRM_6 PF14259.1 EPX74479.1 - 3.5e-34 116.5 0.1 4.3e-11 42.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX74479.1 - 3.6e-34 116.2 0.1 2.8e-12 46.0 0.0 4.5 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74479.1 - 4.2e-24 84.1 0.1 3e-07 30.1 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPX74479.1 - 1e-05 25.1 0.1 0.78 9.5 0.0 3.8 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EPX74479.1 - 4.5e-05 23.2 0.0 0.0047 16.7 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif RRM PF10378.4 EPX74479.1 - 0.00041 19.8 4.4 0.0014 18.1 3.0 2.0 1 0 0 1 1 1 1 Putative RRM domain RNA_bind PF08675.6 EPX74479.1 - 0.0085 16.0 0.0 11 6.1 0.0 3.3 3 0 0 3 3 3 1 RNA binding domain Ank_2 PF12796.2 EPX74480.1 - 4.1e-33 113.5 0.2 4.6e-18 65.3 0.0 2.8 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 EPX74480.1 - 1.9e-32 112.0 15.5 1.9e-32 112.0 10.8 2.5 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.25 EPX74480.1 - 5.3e-32 108.0 7.9 3.4e-07 29.7 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EPX74480.1 - 2.4e-28 97.9 1.4 5.2e-09 36.3 0.0 4.7 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPX74480.1 - 4e-25 87.2 4.3 3.1e-08 33.5 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPX74480.1 - 1.3e-22 77.5 3.2 4.1e-07 29.6 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat DUF3651 PF12371.3 EPX74480.1 - 0.082 12.9 0.7 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3651) MMR_HSR1 PF01926.18 EPX74481.1 - 9.1e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPX74481.1 - 0.012 16.0 0.0 0.037 14.5 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EPX74481.1 - 0.014 14.6 0.1 0.05 12.7 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPX74481.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EPX74481.1 - 0.066 13.3 0.0 0.29 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPX74481.1 - 0.12 12.6 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 ABC transporter ATP-synt_ab PF00006.20 EPX74481.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EPX74481.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SNF5 PF04855.7 EPX74482.1 - 1.1e-77 260.8 0.0 1.5e-77 260.3 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 PHD PF00628.24 EPX74483.1 - 4.3e-16 58.3 25.3 2.8e-11 42.9 6.2 2.6 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 EPX74483.1 - 0.16 11.7 16.9 0.061 13.0 3.7 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.1 EPX74483.1 - 0.7 9.9 9.8 2.4 8.1 1.5 2.6 2 0 0 2 2 2 0 PHD-zinc-finger like domain DNA_pol_lambd_f PF10391.4 EPX74484.1 - 4.3e-21 74.1 0.5 1.2e-20 72.7 0.4 1.8 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EPX74484.1 - 5e-13 49.0 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.1 EPX74484.1 - 6.1e-12 45.0 0.0 1.9e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EPX74484.1 - 2.5e-07 30.7 0.0 4.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm eIF-5_eIF-2B PF01873.12 EPX74485.1 - 2e-43 147.0 0.0 3.3e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EPX74485.1 - 2.1e-20 72.4 1.2 6e-20 70.9 0.9 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon RNA_POL_M_15KD PF02150.11 EPX74485.1 - 0.12 12.1 0.1 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Med1 PF10744.4 EPX74486.1 - 2.3e-23 82.6 5.4 7.7e-22 77.6 3.8 2.1 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.20 EPX74487.1 - 1.4e-52 178.4 0.0 2.5e-52 177.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74487.1 - 3.7e-15 55.7 0.1 1.2e-14 54.0 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EPX74487.1 - 0.0092 14.8 0.1 0.015 14.1 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EPX74487.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NIF PF03031.13 EPX74488.1 - 8e-49 165.3 0.1 1.1e-48 164.9 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Cys_rich_VLP PF14194.1 EPX74488.1 - 0.14 11.9 0.4 3.3 7.5 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich VLP AlaDh_PNT_N PF05222.10 EPX74489.1 - 6.2e-29 100.7 0.0 8.6e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EPX74489.1 - 2.5e-18 66.1 0.0 3.5e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF3128 PF11326.3 EPX74490.1 - 3.2e-23 81.6 3.1 4.4e-23 81.2 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) CLTH PF10607.4 EPX74491.1 - 1.8e-25 89.3 2.2 2.2e-25 89.0 0.1 2.2 2 1 1 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EPX74491.1 - 4.4e-17 61.5 0.8 4.4e-17 61.5 0.6 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.7 EPX74491.1 - 3.7e-05 23.0 0.1 7.5e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EPX74491.1 - 0.00068 19.4 0.6 0.00068 19.4 0.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EPX74491.1 - 0.0016 18.0 2.4 0.0023 17.6 0.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPX74491.1 - 0.013 15.3 2.5 0.02 14.7 0.6 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EPX74491.1 - 0.024 14.6 1.8 0.14 12.2 0.5 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX74491.1 - 0.058 13.0 3.0 0.075 12.7 0.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX74491.1 - 0.058 13.0 0.4 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pellino PF04710.9 EPX74491.1 - 0.059 12.0 0.2 0.092 11.3 0.1 1.2 1 0 0 1 1 1 0 Pellino E1-E2_ATPase PF00122.15 EPX74492.1 - 6.9e-49 165.9 0.7 1.6e-48 164.7 0.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPX74492.1 - 1.6e-39 136.5 0.0 9.4e-39 134.0 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPX74492.1 - 3.9e-11 43.4 0.0 6e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EPX74492.1 - 1.6e-09 37.7 0.1 3.9e-08 33.3 0.0 2.7 2 0 0 2 2 2 1 Heavy-metal-associated domain CofC PF01983.11 EPX74492.1 - 0.016 14.2 0.4 0.038 12.9 0.1 1.7 2 0 0 2 2 2 0 Guanylyl transferase CofC like Hydrolase_6 PF13344.1 EPX74492.1 - 0.055 13.3 0.0 0.73 9.7 0.0 2.9 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase PRA-CH PF01502.13 EPX74493.1 - 4e-25 87.2 0.3 6.8e-25 86.4 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EPX74493.1 - 2.2e-12 47.1 0.0 4.9e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EPX74493.1 - 0.0047 16.8 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain PrpR_N PF06506.6 EPX74493.1 - 0.075 12.4 0.1 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 Propionate catabolism activator CybS PF05328.7 EPX74494.1 - 4.1e-52 175.3 0.0 4.8e-52 175.0 0.0 1.0 1 0 0 1 1 1 1 CybS Peptidase_M16 PF00675.15 EPX74495.1 - 2.1e-51 173.5 3.2 7.8e-51 171.7 1.4 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EPX74495.1 - 7.3e-40 136.5 0.0 3e-38 131.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF2624 PF11116.3 EPX74495.1 - 0.081 13.4 0.2 1.1e+02 3.3 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2624) FRG1 PF06229.7 EPX74496.1 - 4.7e-21 75.1 0.2 1.2e-20 73.8 0.1 1.6 1 1 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EPX74496.1 - 1.4e-06 28.3 0.2 2.5e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Fascin domain ORC4_C PF14629.1 EPX74497.1 - 8.9e-38 129.7 3.0 9.6e-38 129.6 1.1 1.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EPX74497.1 - 7e-16 58.7 0.2 1.1e-14 54.8 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPX74497.1 - 6.8e-06 26.2 0.0 5.3e-05 23.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 EPX74497.1 - 0.00019 21.6 0.0 0.00058 20.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AT_hook PF02178.14 EPX74497.1 - 0.0014 18.0 43.7 0.16 11.6 2.5 4.9 4 0 0 4 4 4 3 AT hook motif DUF815 PF05673.8 EPX74497.1 - 0.0079 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EPX74497.1 - 0.02 14.8 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EPX74497.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EPX74497.1 - 0.074 12.7 0.1 0.46 10.1 0.1 2.1 1 1 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 EPX74497.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain ELL PF10390.4 EPX74498.1 - 6.8e-23 81.2 6.4 6.8e-23 81.2 4.4 3.2 2 2 1 3 3 3 1 RNA polymerase II elongation factor ELL GWT1 PF06423.7 EPX74499.1 - 0.019 15.0 1.0 0.028 14.5 0.7 1.2 1 0 0 1 1 1 0 GWT1 DUF2401 PF10287.4 EPX74500.1 - 1.5e-96 322.4 6.3 3.3e-96 321.3 4.4 1.6 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EPX74500.1 - 1.5e-27 95.4 0.1 3.9e-27 94.2 0.1 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Pkinase PF00069.20 EPX74501.1 - 2.5e-21 75.9 0.0 4e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74501.1 - 1.6e-11 43.7 0.0 3.2e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Sld5 PF05916.6 EPX74502.1 - 5.9e-07 29.7 0.0 1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Actin PF00022.14 EPX74503.1 - 1.6e-130 435.1 0.0 1.8e-130 434.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPX74503.1 - 4.4e-05 22.2 0.0 0.14 10.7 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DUF2201_N PF13203.1 EPX74503.1 - 0.017 14.2 0.1 0.028 13.6 0.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1134 PF06577.7 EPX74503.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) RNA_pol_Rpb2_6 PF00562.23 EPX74504.1 - 1.6e-112 376.0 0.1 2.4e-112 375.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPX74504.1 - 6.6e-40 136.1 0.1 9.7e-40 135.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EPX74504.1 - 3.6e-24 84.2 0.0 9.7e-24 82.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EPX74504.1 - 3.4e-23 82.0 0.0 5.9e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 EPX74504.1 - 3.5e-21 74.9 0.0 8.5e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EPX74504.1 - 1.3e-15 57.3 0.1 4e-15 55.8 0.1 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EPX74504.1 - 0.00027 20.8 0.0 0.00057 19.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 zf-Sec23_Sec24 PF04810.10 EPX74504.1 - 0.12 11.9 3.0 0.42 10.2 0.2 2.8 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Mito_carr PF00153.22 EPX74505.1 - 1.4e-58 194.5 1.7 2.2e-19 68.9 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF2109 PF09882.4 EPX74505.1 - 0.014 15.2 0.8 0.068 13.1 0.0 2.4 3 1 0 3 3 3 0 Predicted membrane protein (DUF2109) POM121 PF15229.1 EPX74505.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 POM121 family CLAMP PF14769.1 EPX74506.1 - 0.043 13.9 4.5 0.85 9.8 0.5 2.0 1 1 1 2 2 2 0 Flagellar C1a complex subunit C1a-32 SNF5 PF04855.7 EPX74506.1 - 0.1 12.0 3.3 0.12 11.7 2.3 1.0 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 Syntaxin-6_N PF09177.6 EPX74506.1 - 0.12 12.7 7.0 0.16 12.3 2.8 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF2730 PF10805.3 EPX74506.1 - 0.17 11.6 4.4 0.22 11.2 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) APG6 PF04111.7 EPX74506.1 - 0.18 10.8 10.3 0.21 10.6 7.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4140 PF13600.1 EPX74506.1 - 6.8 7.1 8.6 1.1 9.7 2.4 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) SWI-SNF_Ssr4 PF08549.5 EPX74507.1 - 9.7e-27 93.5 5.3 8e-25 87.2 3.6 2.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Cullin PF00888.17 EPX74508.1 - 1.5e-50 172.3 3.3 3.1e-50 171.3 2.3 1.5 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EPX74508.1 - 1.6e-25 89.1 0.1 6.3e-25 87.2 0.1 2.1 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Complex1_LYR PF05347.10 EPX74509.1 - 7.3e-10 38.4 0.0 1.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPX74509.1 - 1.2e-06 28.6 0.1 1.5e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EPX74509.1 - 1.8e-06 28.3 0.4 2.7e-06 27.7 0.3 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Pkr1 PF08636.5 EPX74510.1 - 4.5e-27 93.9 8.8 5.3e-27 93.6 6.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4131 PF13567.1 EPX74510.1 - 0.015 14.7 0.2 0.017 14.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) O-antigen_lig PF13425.1 EPX74510.1 - 0.019 14.9 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3796 PF12676.2 EPX74510.1 - 0.071 13.3 0.3 0.086 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) Phage_Gp23 PF10669.4 EPX74510.1 - 0.099 12.7 0.0 0.24 11.5 0.0 1.6 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) PAP2 PF01569.16 EPX74510.1 - 0.16 11.6 2.2 0.23 11.1 1.5 1.3 1 0 0 1 1 1 0 PAP2 superfamily DUF3357 PF11837.3 EPX74510.1 - 0.22 11.3 1.0 0.93 9.3 0.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Med14 PF08638.6 EPX74511.1 - 3.9e-54 182.8 0.5 7e-54 182.0 0.3 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 TruD PF01142.13 EPX74512.1 - 6.2e-65 219.3 0.0 5.8e-64 216.1 0.0 2.3 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) DUF148 PF02520.12 EPX74513.1 - 0.001 18.8 0.3 0.3 10.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function DUF148 STAT_alpha PF01017.15 EPX74513.1 - 0.022 14.4 0.5 0.16 11.6 0.0 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain BLOC1_2 PF10046.4 EPX74513.1 - 0.086 12.9 0.4 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HbrB PF08539.6 EPX74513.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 HbrB-like DASH_Dad3 PF08656.5 EPX74513.1 - 0.39 10.4 2.9 0.75 9.5 2.0 1.6 1 1 0 1 1 1 0 DASH complex subunit Dad3 Cpn60_TCP1 PF00118.19 EPX74514.1 - 4.7e-156 520.1 0.1 5.4e-156 519.9 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sof1 PF04158.9 EPX74515.1 - 3.4e-31 107.1 13.8 5.8e-31 106.3 9.6 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.27 EPX74515.1 - 1.9e-30 103.6 12.9 3.3e-10 39.4 0.0 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EPX74515.1 - 4.8e-05 23.1 0.1 0.00039 20.1 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 EPX74515.1 - 0.026 14.2 0.1 0.5 10.1 0.0 3.0 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Mmp37 PF09139.6 EPX74516.1 - 2e-98 329.4 1.8 2.3e-98 329.2 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 DGF-1_C PF11040.3 EPX74518.1 - 0.093 12.6 0.5 4 7.3 0.3 2.9 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DNA_topoisoIV PF00521.15 EPX74519.1 - 7.5e-125 417.1 0.0 1.2e-124 416.4 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EPX74519.1 - 8e-37 126.1 0.8 1.8e-36 124.9 0.6 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EPX74519.1 - 3.1e-13 49.5 0.0 1.1e-12 47.8 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EPX74519.1 - 4.9e-10 39.1 0.0 1.6e-09 37.4 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Iso_dh PF00180.15 EPX74520.1 - 1.4e-128 428.7 0.0 1.5e-128 428.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase APC10 PF03256.11 EPX74521.1 - 2.5e-64 216.4 0.0 2.7e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EPX74521.1 - 0.0041 16.9 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain GPI-anchored PF10342.4 EPX74522.1 - 1.2e-15 57.7 1.5 1.2e-15 57.7 1.0 2.6 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PAP1 PF08601.5 EPX74522.1 - 8.7 5.9 27.0 13 5.3 18.7 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 ubiquitin PF00240.18 EPX74524.1 - 1.5e-13 49.9 0.3 5.3e-13 48.1 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.4 EPX74524.1 - 0.00015 21.9 0.1 0.00049 20.2 0.0 1.9 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EPX74524.1 - 0.00017 21.4 0.0 0.00049 19.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 EPX74524.1 - 0.00044 19.8 0.5 0.0021 17.7 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2206 PF09971.4 EPX74524.1 - 0.1 11.4 0.2 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) PS_Dcarbxylase PF02666.10 EPX74525.1 - 2.8e-78 261.8 0.0 2.3e-76 255.6 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Cyclin_N PF00134.18 EPX74526.1 - 1.6e-25 89.0 0.0 3.8e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPX74526.1 - 4.9e-19 68.3 0.6 3e-18 65.8 0.1 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain COX16 PF14138.1 EPX74527.1 - 4.4 7.5 11.9 20 5.4 0.5 3.8 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 HSBP1 PF06825.7 EPX74528.1 - 1.2e-07 31.1 0.4 1.9e-07 30.5 0.3 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 EPX74528.1 - 0.0031 16.8 0.2 0.058 12.7 0.1 2.1 1 1 1 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin DUF883 PF05957.8 EPX74528.1 - 0.033 14.5 0.0 0.04 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Cation_efflux PF01545.16 EPX74529.1 - 3.6e-26 91.9 12.6 4.5e-26 91.5 8.7 1.1 1 0 0 1 1 1 1 Cation efflux family Pex24p PF06398.6 EPX74529.1 - 6.5 5.4 10.2 32 3.1 7.1 1.9 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Pkinase PF00069.20 EPX74530.1 - 4.9e-47 160.2 0.0 7.9e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74530.1 - 4.4e-27 94.7 0.0 6.4e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX74530.1 - 0.0012 18.5 3.2 0.19 11.4 1.1 3.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPX74530.1 - 0.0031 16.5 0.0 0.013 14.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPX74530.1 - 0.0033 16.5 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cyclin_N PF00134.18 EPX74531.1 - 6e-12 45.2 0.4 6.4e-10 38.6 0.2 2.8 2 1 0 2 2 2 2 Cyclin, N-terminal domain Pex24p PF06398.6 EPX74532.1 - 5.7e-05 22.0 5.0 5.7e-05 22.0 3.5 1.5 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Peptidase_S10 PF00450.17 EPX74533.1 - 2.3e-73 247.7 0.9 3e-73 247.3 0.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase COX5B PF01215.14 EPX74534.1 - 9.3e-55 184.0 0.0 1.1e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb ADK_lid PF05191.9 EPX74534.1 - 0.064 12.9 0.3 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-ISL3 PF14690.1 EPX74534.1 - 0.1 12.6 1.0 0.17 11.9 0.7 1.3 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PGM_PMM_I PF02878.11 EPX74535.1 - 2e-11 43.5 0.8 9.9e-07 28.3 0.0 3.5 4 0 0 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 EPX74535.1 - 6.7e-11 42.0 0.1 1.4e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 EPX74535.1 - 3.9e-09 36.7 0.7 2e-08 34.4 0.1 2.6 3 1 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II bZIP_1 PF00170.16 EPX74536.1 - 1.1e-12 47.7 10.0 2.2e-12 46.7 6.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPX74536.1 - 5.8e-09 35.6 7.5 1.2e-08 34.6 5.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper HAP1_N PF04849.8 EPX74536.1 - 0.011 14.7 6.3 0.02 13.8 4.4 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region bZIP_Maf PF03131.12 EPX74536.1 - 0.019 15.2 6.1 0.044 14.0 4.3 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor HALZ PF02183.13 EPX74536.1 - 0.027 14.1 0.2 0.058 13.1 0.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4239 PF14023.1 EPX74536.1 - 0.18 11.1 0.2 0.27 10.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) V_ATPase_I PF01496.14 EPX74536.1 - 0.46 8.2 2.1 0.61 7.8 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ASD2 PF08687.6 EPX74536.1 - 6.9 5.9 10.4 21 4.3 7.2 1.7 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 SNF2_N PF00176.18 EPX74537.1 - 3.8e-57 193.3 0.9 5.6e-57 192.8 0.6 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPX74537.1 - 3.5e-11 42.7 0.0 8.6e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX74537.1 - 8.3e-08 32.2 0.3 1.2e-06 28.5 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPX74537.1 - 1.3e-06 28.0 0.0 2.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Vps5 PF09325.5 EPX74538.1 - 6.3e-10 38.7 10.5 1.1e-09 37.9 7.3 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EPX74538.1 - 4.2e-09 36.1 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 PX domain FAD_binding_1 PF00667.15 EPX74539.1 - 2.7e-31 108.7 0.0 3.6e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EPX74539.1 - 1.3e-29 103.0 0.0 3e-29 101.8 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EPX74539.1 - 8.2e-16 58.5 0.0 1.7e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF500 PF04366.7 EPX74540.1 - 2.7e-43 146.4 0.1 4.1e-43 145.8 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EPX74540.1 - 1.4e-15 56.3 0.1 2.8e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPX74540.1 - 3.6e-12 45.5 0.0 6.9e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EPX74540.1 - 1.1e-11 44.1 0.0 2.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M24 PF00557.19 EPX74541.1 - 7e-43 146.6 0.0 1.2e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EPX74541.1 - 4.6e-23 82.1 0.0 6.2e-17 62.3 0.0 2.8 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain THF_DHG_CYH PF00763.18 EPX74541.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain IBN_N PF03810.14 EPX74542.1 - 0.027 14.3 0.6 0.027 14.3 0.4 3.0 3 0 0 3 3 3 0 Importin-beta N-terminal domain UCH_1 PF13423.1 EPX74544.1 - 2.6e-48 164.9 0.0 3.9e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EPX74544.1 - 3.4e-30 105.4 0.0 6.2e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EPX74544.1 - 4e-05 22.8 0.1 0.00052 19.2 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EPX74544.1 - 0.01 15.6 0.9 0.94 9.4 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Kri1_C PF12936.2 EPX74545.1 - 1.4e-28 98.6 0.4 1.4e-28 98.6 0.3 4.4 4 1 1 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 EPX74545.1 - 1.5e-26 92.6 10.7 1.5e-26 92.6 7.4 5.4 5 1 1 6 6 6 2 KRI1-like family CPSase_L_D2 PF02786.12 EPX74546.1 - 1.8e-114 380.2 0.1 2.4e-84 281.8 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EPX74546.1 - 9.7e-48 160.9 0.0 3.3e-47 159.2 0.0 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EPX74546.1 - 4.3e-45 153.5 0.0 9.3e-45 152.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 EPX74546.1 - 4.7e-43 145.7 0.0 8.5e-21 74.1 0.0 3.3 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EPX74546.1 - 4e-40 136.3 0.1 8.2e-40 135.4 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace_N PF02729.16 EPX74546.1 - 1.2e-39 135.2 0.0 3e-39 133.9 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EPX74546.1 - 4.3e-38 130.6 0.1 3.8e-37 127.6 0.0 2.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EPX74546.1 - 1.1e-34 119.7 0.1 2.1e-21 76.4 0.0 3.7 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPX74546.1 - 4.7e-24 84.7 0.1 4.8e-12 45.2 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EPX74546.1 - 1e-19 70.2 0.0 5.4e-19 67.9 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EPX74546.1 - 1.3e-17 63.8 0.6 2.4e-09 36.8 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EPX74546.1 - 2.6e-15 56.2 0.1 1.3e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EPX74546.1 - 1.3e-06 28.4 0.4 0.0095 15.8 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EPX74546.1 - 1.9e-05 24.1 0.4 0.0021 17.5 0.0 2.8 2 1 0 2 2 2 1 Peptidase C26 RimK PF08443.6 EPX74546.1 - 0.00011 21.7 0.0 0.0034 16.8 0.0 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EPX74546.1 - 0.0056 16.2 0.2 1.2 8.6 0.0 3.1 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_C PF02843.11 EPX74546.1 - 0.047 13.8 0.4 8.2 6.6 0.0 3.0 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain MT-A70 PF05063.9 EPX74547.1 - 4.8e-37 127.1 0.7 7.4e-37 126.5 0.5 1.3 1 0 0 1 1 1 1 MT-A70 Pkinase PF00069.20 EPX74548.1 - 3e-53 180.6 0.0 4.5e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74548.1 - 2.7e-19 69.2 0.0 3.8e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX74548.1 - 0.00036 20.3 0.6 0.0028 17.4 0.1 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EPX74548.1 - 0.047 12.7 0.1 0.084 11.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPX74548.1 - 0.11 11.3 0.0 0.3 10.0 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Nucleoporin_FG PF13634.1 EPX74549.1 - 1.8e-15 57.1 86.3 2.4e-07 30.9 34.7 3.3 1 1 1 2 2 2 2 Nucleoporin FG repeat region ArsR PF09824.4 EPX74549.1 - 0.051 12.8 0.1 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 ArsR transcriptional regulator Lge1 PF11488.3 EPX74549.1 - 5.1 7.3 8.9 9.2 6.5 1.8 3.0 2 2 0 2 2 2 0 Transcriptional regulatory protein LGE1 Fip1 PF05182.8 EPX74550.1 - 1.1e-25 88.6 0.8 2.2e-25 87.6 0.5 1.5 1 0 0 1 1 1 1 Fip1 motif Con-6 PF10346.4 EPX74551.1 - 1e-16 60.0 0.2 1e-16 60.0 0.1 1.7 2 0 0 2 2 2 1 Conidiation protein 6 SecE PF00584.15 EPX74552.1 - 6.7e-12 44.8 0.0 7.5e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex PUF PF00806.14 EPX74553.1 - 1.4e-55 181.7 9.3 5.9e-08 31.7 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RabGAP-TBC PF00566.13 EPX74554.1 - 2e-46 158.1 0.0 4.5e-46 157.0 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EPX74555.1 - 5.4e-68 228.9 0.0 1.2e-67 227.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74555.1 - 1.4e-28 99.7 0.1 2.1e-27 95.8 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX74555.1 - 1.6e-06 27.3 0.1 0.052 12.5 0.0 2.9 2 1 0 3 3 3 2 Kinase-like Kdo PF06293.9 EPX74555.1 - 0.029 13.4 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX74555.1 - 0.086 12.5 0.0 4.7 6.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Met_10 PF02475.11 EPX74556.1 - 1.8e-11 43.9 0.0 3.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EPX74556.1 - 0.034 14.1 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EPX74557.1 - 7.8e-23 80.7 0.1 2.3e-18 66.0 0.1 3.1 2 1 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EPX74557.1 - 8.9e-10 38.3 0.0 1.8e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 EPX74557.1 - 1.6e-08 34.1 0.0 3.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Cons_hypoth95 PF03602.10 EPX74557.1 - 3.3e-06 26.6 0.0 5.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.8 EPX74557.1 - 4.3e-06 26.0 0.0 6.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EPX74557.1 - 5e-06 27.0 0.0 1.1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EPX74557.1 - 7e-06 25.6 0.1 1.4e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EPX74557.1 - 8.8e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPX74557.1 - 1.1e-05 24.5 0.0 2.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EPX74557.1 - 5.3e-05 23.5 0.0 0.00023 21.4 0.0 2.1 3 0 0 3 3 1 1 Methyltransferase domain Met_10 PF02475.11 EPX74557.1 - 5.3e-05 22.9 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 EPX74557.1 - 9e-05 21.9 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EPX74557.1 - 9.1e-05 22.8 0.0 0.00033 21.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX74557.1 - 0.007 16.8 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPX74557.1 - 0.056 12.5 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 EPX74557.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DDE_1 PF03184.14 EPX74558.1 - 1.2e-50 171.6 1.4 2.2e-50 170.8 0.2 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EPX74558.1 - 1e-16 60.4 3.3 2e-16 59.5 1.4 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain PARP PF00644.15 EPX74558.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain Mito_carr PF00153.22 EPX74559.1 - 1.3e-39 133.8 6.7 4.1e-18 64.8 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1 PF00133.17 EPX74560.1 - 6.5e-61 206.0 5.3 4.8e-23 81.0 0.3 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EPX74560.1 - 1.5e-40 138.4 0.0 4.2e-40 137.0 0.0 1.7 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EPX74560.1 - 1.7e-28 99.4 1.4 1.3e-22 80.0 1.0 4.4 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EPX74560.1 - 2.1e-14 53.5 0.2 4.6e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EPX74560.1 - 0.00044 19.1 0.0 0.00079 18.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) V-SNARE_C PF12352.3 EPX74561.1 - 8e-17 61.0 0.4 8e-17 61.0 0.3 2.4 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Prosystemin PF07376.6 EPX74561.1 - 0.0036 16.7 0.3 0.004 16.5 0.2 1.1 1 0 0 1 1 1 1 Prosystemin FEZ PF07763.8 EPX74561.1 - 0.019 14.6 7.1 0.026 14.2 4.9 1.1 1 0 0 1 1 1 0 FEZ-like protein TAT_ubiq PF07706.7 EPX74561.1 - 0.022 14.6 0.9 0.038 13.9 0.2 1.8 2 0 0 2 2 2 0 Aminotransferase ubiquitination site BMFP PF04380.8 EPX74561.1 - 0.061 13.4 2.5 0.25 11.4 0.0 2.6 2 1 1 3 3 3 0 Membrane fusogenic activity TEX12 PF15219.1 EPX74561.1 - 0.19 11.7 5.1 2.3 8.2 0.1 2.7 1 1 1 2 2 2 0 Testis-expressed 12 DUF3365 PF11845.3 EPX74561.1 - 0.2 11.4 1.1 0.88 9.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) DUF4570 PF15134.1 EPX74561.1 - 0.27 11.0 6.2 0.21 11.4 3.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) DUF948 PF06103.6 EPX74561.1 - 0.54 10.1 2.6 11 5.9 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ATP-synt_10 PF05176.9 EPX74562.1 - 3.5e-49 167.3 0.2 5.3e-49 166.7 0.1 1.2 1 0 0 1 1 1 1 ATP10 protein Glyco_transf_22 PF03901.12 EPX74563.1 - 1.8e-64 218.3 41.4 2.2e-64 218.0 28.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 EPX74563.1 - 0.0021 17.9 32.1 0.045 13.6 7.7 2.6 1 1 1 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase Tmemb_14 PF03647.8 EPX74563.1 - 5.2 7.5 11.4 1 9.7 0.7 2.9 2 0 0 2 2 2 0 Transmembrane proteins 14C zf-C2H2 PF00096.21 EPX74564.1 - 4.6e-14 51.8 18.5 3.3e-06 27.1 1.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPX74564.1 - 1.2e-09 37.9 18.4 9.2e-07 28.8 0.4 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPX74564.1 - 1.6e-09 37.4 16.0 0.00058 20.0 0.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPX74564.1 - 8.1e-05 22.6 7.1 0.095 12.8 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPX74564.1 - 0.00046 20.2 8.8 1.2 9.4 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type Tmpp129 PF10272.4 EPX74564.1 - 0.039 12.6 1.4 0.061 12.0 1.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-C2H2_6 PF13912.1 EPX74564.1 - 0.047 13.6 6.4 2.2 8.3 0.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EPX74564.1 - 0.84 9.7 6.5 8.1 6.6 0.2 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.11 EPX74564.1 - 8.7 6.3 8.8 2.5 8.0 1.6 2.6 1 1 1 2 2 2 0 AN1-like Zinc finger PfkB PF00294.19 EPX74565.1 - 2.1e-13 50.0 0.0 3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PNP_UDP_1 PF01048.15 EPX74566.1 - 2.5e-32 111.7 0.0 2.8e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily NMD3 PF04981.8 EPX74567.1 - 8e-75 250.9 5.8 1.1e-74 250.5 4.0 1.2 1 0 0 1 1 1 1 NMD3 family RbsD_FucU PF05025.8 EPX74567.1 - 0.083 13.2 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 RbsD / FucU transport protein family zf-RING_4 PF14570.1 EPX74568.1 - 7e-21 73.5 12.3 7e-21 73.5 8.5 1.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EPX74568.1 - 2.3e-06 27.1 0.0 5e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74568.1 - 2e-05 24.3 0.0 4.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 EPX74568.1 - 0.00041 20.0 2.4 0.00041 20.0 1.7 1.9 2 0 0 2 2 2 1 Zinc-binding RING-finger Rtf2 PF04641.7 EPX74568.1 - 0.0019 17.4 2.5 0.0028 16.9 1.7 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 EPX74568.1 - 0.0053 16.7 12.3 0.0053 16.7 8.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 EPX74568.1 - 0.029 14.1 3.9 0.069 12.8 2.7 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) RRM_6 PF14259.1 EPX74568.1 - 0.079 12.9 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.24 EPX74569.1 - 3.3e-12 45.8 24.5 3.8e-12 45.7 4.8 2.4 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 EPX74569.1 - 0.00026 20.6 23.8 0.0067 16.1 6.7 3.4 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 EPX74569.1 - 0.0027 17.8 14.2 0.19 11.9 2.0 2.5 2 0 0 2 2 2 2 PHD-like zinc-binding domain Rep_fac-A_C PF08646.5 EPX74569.1 - 0.045 13.4 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Replication factor-A C terminal domain Vps39_2 PF10367.4 EPX74569.1 - 6.5 6.9 7.3 11 6.2 0.5 2.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 UPF1_Zn_bind PF09416.5 EPX74570.1 - 6.6e-72 240.0 5.4 1.4e-71 238.9 3.8 1.6 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EPX74570.1 - 1.7e-58 197.3 0.0 3.8e-58 196.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPX74570.1 - 5.6e-55 186.4 1.1 9.3e-55 185.7 0.7 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPX74570.1 - 8e-15 54.3 0.1 2.4e-14 52.8 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPX74570.1 - 1e-14 54.6 0.2 1.9e-13 50.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EPX74570.1 - 7.3e-07 29.1 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EPX74570.1 - 8.9e-06 25.2 0.0 0.0025 17.1 0.0 2.5 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EPX74570.1 - 0.00025 20.6 0.0 0.13 11.7 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EPX74570.1 - 0.00025 20.1 3.6 0.00039 19.5 0.0 2.9 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EPX74570.1 - 0.0054 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EPX74570.1 - 0.016 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DEAD PF00270.24 EPX74570.1 - 0.021 14.3 0.1 0.047 13.1 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_5 PF07728.9 EPX74570.1 - 0.024 14.3 0.0 5.5 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PhoH PF02562.11 EPX74570.1 - 0.024 13.8 0.0 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein PIF1 PF05970.9 EPX74570.1 - 0.055 12.4 0.0 0.64 8.9 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase Helicase_RecD PF05127.9 EPX74570.1 - 0.07 12.7 0.0 0.21 11.1 0.0 1.7 1 1 0 1 1 1 0 Helicase SNF2_N PF00176.18 EPX74570.1 - 0.084 11.6 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.1 EPX74570.1 - 0.1 12.7 0.0 0.35 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain HTH_WhiA PF02650.9 EPX74570.1 - 0.16 12.3 1.4 0.28 11.6 0.1 2.0 2 0 0 2 2 1 0 WhiA C-terminal HTH domain AAA PF00004.24 EPX74570.1 - 0.17 12.1 0.3 0.38 10.9 0.2 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EPX74570.1 - 0.18 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Pkinase PF00069.20 EPX74571.1 - 3.4e-57 193.5 0.0 5e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74571.1 - 6.7e-24 84.3 0.0 8.3e-23 80.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX74571.1 - 0.0039 16.9 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPX74571.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.6 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 EPX74571.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Urb2 PF10441.4 EPX74572.1 - 2.3e-37 128.7 5.2 2.3e-37 128.7 3.6 3.4 2 1 1 3 3 3 2 Urb2/Npa2 family Sec1 PF00995.18 EPX74573.1 - 7.7e-144 480.4 3.8 8.7e-144 480.2 2.6 1.0 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.18 EPX74574.1 - 3.9e-11 42.5 0.7 6.8e-11 41.7 0.5 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EPX74574.1 - 0.00032 20.4 0.8 0.00073 19.3 0.0 2.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site FAM110_C PF14160.1 EPX74574.1 - 0.42 11.5 3.5 0.26 12.2 0.4 2.0 2 0 0 2 2 2 0 Centrosome-associated C terminus BRO1 PF03097.13 EPX74575.1 - 9.9e-51 172.6 8.5 2.4e-50 171.3 5.9 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EPX74575.1 - 8e-20 70.9 14.1 1.9e-19 69.7 8.5 2.1 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF3538 PF12057.3 EPX74575.1 - 0.1 12.1 0.3 0.51 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3538) AAA PF00004.24 EPX74576.1 - 2.7e-45 153.8 0.0 5e-45 152.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EPX74576.1 - 2.6e-26 91.2 0.0 2.4e-25 88.1 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EPX74576.1 - 7.3e-22 77.0 2.7 2e-21 75.6 1.8 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EPX74576.1 - 3.7e-06 27.7 0.1 1e-05 26.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EPX74576.1 - 4.1e-06 26.9 0.4 0.0012 18.9 0.1 2.7 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EPX74576.1 - 9.4e-06 24.8 0.0 1.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EPX74576.1 - 1.8e-05 24.6 0.0 9.7e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EPX74576.1 - 3.2e-05 23.4 0.0 5.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EPX74576.1 - 5.8e-05 22.8 0.0 0.00024 20.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPX74576.1 - 6e-05 23.1 0.1 0.00095 19.1 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EPX74576.1 - 0.00012 21.5 0.1 0.14 11.5 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.1 EPX74576.1 - 0.00022 21.1 0.0 0.00048 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EPX74576.1 - 0.00027 19.7 0.0 0.00053 18.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EPX74576.1 - 0.00046 19.2 0.0 0.00082 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EPX74576.1 - 0.0011 18.8 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EPX74576.1 - 0.0028 17.8 0.0 0.01 15.9 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_18 PF13238.1 EPX74576.1 - 0.0042 17.3 0.1 0.027 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPX74576.1 - 0.0059 15.7 0.1 0.18 10.8 0.0 2.5 1 1 1 2 2 2 1 Zeta toxin AAA_24 PF13479.1 EPX74576.1 - 0.0063 16.1 0.1 0.027 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EPX74576.1 - 0.016 14.9 0.6 0.66 9.6 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 EPX74576.1 - 0.022 14.4 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EPX74576.1 - 0.026 14.1 0.0 0.69 9.5 0.0 2.3 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.11 EPX74576.1 - 0.029 13.6 0.1 0.078 12.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.12 EPX74576.1 - 0.039 12.8 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.16 EPX74576.1 - 0.039 13.0 0.1 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EPX74576.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 EPX74576.1 - 0.062 13.2 0.1 0.14 12.0 0.0 1.6 2 0 0 2 2 1 0 Cytidylate kinase-like family Sigma54_activat PF00158.21 EPX74576.1 - 0.076 12.4 0.0 0.51 9.7 0.0 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EPX74576.1 - 0.078 12.0 0.1 9.7 5.2 0.0 2.3 1 1 1 2 2 2 0 KaiC Torsin PF06309.6 EPX74576.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_21 PF13304.1 EPX74576.1 - 0.089 12.7 2.2 2.5 7.9 0.0 3.0 2 1 1 3 3 3 0 AAA domain Peptidase_M28 PF04389.12 EPX74576.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 AAA_28 PF13521.1 EPX74576.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PP2C PF00481.16 EPX74577.1 - 8.7e-85 284.1 0.0 1.4e-84 283.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EPX74577.1 - 1.1e-05 24.9 0.0 2.4e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SMN PF06003.7 EPX74578.1 - 5.6e-07 28.9 12.8 0.00036 19.7 6.6 2.6 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) AP-5_subunit_s1 PF15001.1 EPX74578.1 - 0.24 11.3 1.7 0.3 10.9 1.2 1.1 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF221 PF02714.10 EPX74579.1 - 1.7e-97 326.1 21.0 1.7e-97 326.1 14.5 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPX74579.1 - 2e-32 111.9 3.4 2e-32 111.9 2.3 3.6 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EPX74579.1 - 1.2e-12 48.1 0.0 2.7e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EPX74579.1 - 3.9e-05 23.5 0.0 0.023 14.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF746 PF05344.6 EPX74579.1 - 0.0014 18.0 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF746) RRM_1 PF00076.17 EPX74579.1 - 0.0034 16.9 0.0 3.6 7.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ThiF PF00899.16 EPX74580.1 - 4.6e-41 139.8 0.0 1.2e-40 138.4 0.0 1.7 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 EPX74580.1 - 1.8e-28 97.9 0.1 3.2e-28 97.1 0.1 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EPX74580.1 - 2.8e-05 24.4 0.0 0.0001 22.6 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain ELFV_dehydrog PF00208.16 EPX74580.1 - 0.00013 21.6 0.0 0.0019 17.8 0.0 2.0 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Semialdhyde_dh PF01118.19 EPX74580.1 - 0.0059 16.8 0.0 0.58 10.4 0.0 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EPX74580.1 - 0.021 14.9 0.7 1.3 9.0 0.4 3.4 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HA2 PF04408.18 EPX74581.1 - 4.6e-23 81.1 0.1 1.3e-22 79.7 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EPX74581.1 - 1.9e-21 76.0 0.0 4.3e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EPX74581.1 - 1.1e-12 47.6 0.0 3.5e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPX74581.1 - 4.2e-08 32.8 0.0 1.2e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPX74581.1 - 3.6e-06 27.1 0.0 1.3e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPX74581.1 - 0.00031 21.0 0.1 0.0073 16.6 0.1 2.6 1 1 0 1 1 1 1 ABC transporter T2SE PF00437.15 EPX74581.1 - 0.00047 19.1 0.0 0.00097 18.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EPX74581.1 - 0.00096 19.0 0.3 0.013 15.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EPX74581.1 - 0.0049 16.0 0.0 0.029 13.5 0.0 2.1 2 0 0 2 2 2 1 KaiC Arch_ATPase PF01637.13 EPX74581.1 - 0.0052 16.4 0.0 0.03 14.0 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase ResIII PF04851.10 EPX74581.1 - 0.0061 16.4 0.7 3.9 7.2 0.0 2.8 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 EPX74581.1 - 0.0063 15.6 0.0 0.018 14.1 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EPX74581.1 - 0.0094 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 EPX74581.1 - 0.013 14.9 0.0 0.036 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EPX74581.1 - 0.023 14.7 0.0 0.18 11.8 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain DUF2075 PF09848.4 EPX74581.1 - 0.03 13.3 0.0 0.056 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Peptidase_M16_C PF05193.16 EPX74581.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase M16 inactive domain AAA_33 PF13671.1 EPX74581.1 - 0.061 13.1 0.0 0.2 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EPX74581.1 - 0.069 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EPX74581.1 - 0.098 12.0 0.5 2.4 7.5 0.0 2.7 2 1 0 3 3 3 0 AAA-like domain AAA_30 PF13604.1 EPX74581.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EPX74581.1 - 6.4 7.0 14.9 0.19 12.0 0.2 2.9 2 1 1 3 3 3 0 AAA domain Helicase_C PF00271.26 EPX74582.1 - 4e-21 74.6 0.0 1.7e-18 66.2 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EPX74582.1 - 6.6e-21 74.5 0.0 9e-20 70.8 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase RQC PF09382.5 EPX74582.1 - 7.6e-19 67.4 0.0 2e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EPX74582.1 - 3e-14 52.4 0.0 7e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Helicase_Sgs1 PF11408.3 EPX74582.1 - 0.0056 16.4 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Sgs1 RecQ helicase GPP34 PF05719.6 EPX74582.1 - 0.22 11.5 0.1 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) ATG22 PF11700.3 EPX74583.1 - 7.3e-96 321.5 19.2 8.7e-96 321.2 13.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF3591 PF12157.3 EPX74584.1 - 2.4e-198 659.1 0.6 3.8e-198 658.5 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EPX74584.1 - 2.6e-05 23.7 1.6 6e-05 22.6 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EPX74584.1 - 0.008 16.0 1.2 0.014 15.3 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle Methyltransf_15 PF09445.5 EPX74585.1 - 1.2e-45 155.0 0.0 1.5e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EPX74585.1 - 2e-07 31.0 0.0 1e-06 28.7 0.0 1.8 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX74585.1 - 0.00011 21.8 0.0 0.00029 20.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EPX74585.1 - 0.0019 17.8 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EPX74585.1 - 0.0051 17.3 0.0 0.0065 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EPX74585.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Cons_hypoth95 PF03602.10 EPX74585.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 WLM PF08325.5 EPX74586.1 - 6.8e-45 153.2 0.0 1.4e-44 152.2 0.0 1.4 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 EPX74586.1 - 0.00018 21.3 0.1 0.00036 20.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 EPX74586.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 SprT-like family Reprolysin_5 PF13688.1 EPX74586.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EPX74586.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like adh_short PF00106.20 EPX74587.1 - 5.9e-32 110.8 0.0 7.3e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPX74587.1 - 2.3e-14 53.7 0.0 2.9e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPX74587.1 - 1.7e-10 40.8 0.0 2.1e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPX74587.1 - 0.00071 18.5 0.1 0.0025 16.7 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EPX74587.1 - 0.015 15.0 0.1 0.03 14.1 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 EPX74587.1 - 0.051 12.5 0.1 0.054 12.4 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Na_Ca_ex PF01699.19 EPX74588.1 - 1.2e-26 92.9 35.2 4.4e-17 61.9 7.7 3.4 4 1 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EPX74588.1 - 2.6e-08 34.1 10.8 2.6e-08 34.1 7.5 3.9 3 0 0 3 3 3 2 Domain of unknown function (DUF307) Ribosomal_S8e PF01201.17 EPX74589.1 - 6.2e-51 172.0 1.2 7.1e-51 171.8 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EPX74589.1 - 0.029 14.6 0.2 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Small acidic protein family RNA_pol_Rpb2_6 PF00562.23 EPX74590.1 - 9.2e-126 419.6 0.2 1.6e-125 418.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPX74590.1 - 2e-74 248.8 0.1 3.1e-74 248.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EPX74590.1 - 5.9e-53 179.1 0.3 1.1e-52 178.1 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EPX74590.1 - 1.9e-28 98.0 0.3 7.3e-28 96.1 0.2 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_7 PF04560.15 EPX74590.1 - 4.1e-27 94.2 0.0 1.1e-26 92.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EPX74590.1 - 4.3e-23 81.0 0.7 1.1e-22 79.7 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EPX74590.1 - 4.4e-23 80.8 0.0 9.8e-23 79.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 EF-hand_like PF09279.6 EPX74590.1 - 0.11 12.5 0.6 0.89 9.6 0.2 2.3 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like RNA_pol_Rpb2_45 PF10385.4 EPX74590.1 - 0.13 12.0 0.3 1.5 8.7 0.1 2.7 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain Condensation PF00668.15 EPX74591.1 - 9.3e-173 573.0 0.0 4.5e-36 124.2 0.0 7.8 7 0 0 7 7 7 7 Condensation domain AMP-binding PF00501.23 EPX74591.1 - 2.2e-171 569.8 0.0 2.8e-86 289.5 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme PP-binding PF00550.20 EPX74591.1 - 4.9e-40 135.6 13.3 1.5e-08 34.7 0.1 6.7 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPX74591.1 - 9.2e-08 32.9 0.0 0.0038 18.1 0.0 3.0 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.11 EPX74591.1 - 2.8 7.4 0.0 62 3.0 0.0 2.5 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain K_oxygenase PF13434.1 EPX74592.1 - 7.4e-100 334.1 0.0 8.7e-100 333.9 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EPX74592.1 - 4.5e-13 49.2 0.1 9e-11 41.7 0.0 2.5 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPX74592.1 - 1e-09 38.7 0.0 5.2e-08 33.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPX74592.1 - 3.9e-05 23.6 0.0 0.02 14.7 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase INO80_Ies4 PF08193.6 EPX74593.1 - 2e-32 112.9 11.7 3.8e-32 112.0 8.1 1.4 1 1 0 1 1 1 1 INO80 complex subunit Ies4 RGS PF00615.14 EPX74594.1 - 0.00018 21.5 0.1 0.00084 19.4 0.0 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Nop PF01798.13 EPX74595.1 - 4.9e-57 191.4 1.8 1.1e-56 190.3 1.2 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EPX74595.1 - 5.4e-28 96.5 0.0 9.8e-28 95.7 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EPX74595.1 - 1.4e-20 73.2 1.5 1.4e-20 73.2 1.0 2.8 2 1 1 3 3 3 1 NOP5NT (NUC127) domain FA_desaturase PF00487.19 EPX74596.1 - 0.02 14.3 1.0 0.027 13.9 0.7 1.2 1 0 0 1 1 1 0 Fatty acid desaturase CaKB PF03185.10 EPX74596.1 - 0.079 12.3 0.3 0.24 10.7 0.0 1.9 1 1 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Tic20 PF09685.5 EPX74596.1 - 0.14 12.1 13.1 0.23 11.4 9.1 1.3 1 0 0 1 1 1 0 Tic20-like protein DUF1129 PF06570.6 EPX74596.1 - 0.16 11.2 2.9 0.23 10.7 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2207 PF09972.4 EPX74596.1 - 1.4 7.3 5.2 2.1 6.8 3.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1469 PF07332.6 EPX74596.1 - 8.7 6.0 8.0 14 5.4 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) WTF PF03303.8 EPX74597.1 - 5.5e-07 29.2 0.5 7.9e-07 28.7 0.4 1.2 1 0 0 1 1 1 1 WTF protein UPF0233 PF06781.7 EPX74597.1 - 0.0025 17.3 2.0 0.0073 15.9 1.4 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0233) DUF1129 PF06570.6 EPX74597.1 - 0.011 15.0 2.7 0.016 14.5 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Presenilin PF01080.12 EPX74597.1 - 0.021 13.6 0.8 0.027 13.3 0.5 1.3 1 0 0 1 1 1 0 Presenilin FA_desaturase PF00487.19 EPX74597.1 - 0.035 13.5 1.2 0.069 12.5 0.9 1.3 1 1 0 1 1 1 0 Fatty acid desaturase Synaptobrevin PF00957.16 EPX74597.1 - 0.045 13.3 0.1 0.045 13.3 0.1 3.1 5 0 0 5 5 5 0 Synaptobrevin DUF1230 PF06799.6 EPX74597.1 - 0.56 10.0 4.0 0.26 11.1 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) DUF912 PF06024.7 EPX74597.1 - 2.6 8.1 9.2 0.63 10.1 0.1 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2207 PF09972.4 EPX74597.1 - 5 5.5 14.6 0.15 10.5 3.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF3671 PF12420.3 EPX74597.1 - 5 7.1 9.1 0.73 9.8 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function UCH PF00443.24 EPX74600.1 - 1.7e-47 161.8 5.7 2.7e-46 157.8 4.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPX74600.1 - 2e-14 53.7 15.5 1.1e-13 51.3 7.3 3.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPX74600.1 - 1.4e-08 34.7 7.9 1.4e-08 34.7 5.5 3.2 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein TAF4 PF05236.9 EPX74601.1 - 3.7e-60 203.4 5.7 4.3e-60 203.2 4.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF1657 PF07870.6 EPX74601.1 - 0.056 13.1 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) SWIB PF02201.13 EPX74602.1 - 3.1e-21 74.8 0.0 1.1e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain K-box PF01486.12 EPX74602.1 - 0.053 13.3 7.1 0.044 13.5 3.3 2.1 2 0 0 2 2 2 0 K-box region PCI PF01399.22 EPX74603.1 - 6.1e-21 74.7 0.4 8.9e-20 70.9 0.1 3.0 3 1 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EPX74603.1 - 0.00038 20.2 0.2 0.001 18.8 0.1 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_16 PF13432.1 EPX74603.1 - 0.00041 20.9 6.6 0.0047 17.5 0.0 4.0 4 1 1 5 5 4 1 Tetratricopeptide repeat FadR_C PF07840.7 EPX74603.1 - 0.0046 16.5 0.4 0.014 15.0 0.3 1.8 1 0 0 1 1 1 1 FadR C-terminal domain TPR_7 PF13176.1 EPX74603.1 - 0.0074 16.0 3.9 2.1 8.3 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPX74603.1 - 0.021 14.5 10.1 4.1 7.3 0.0 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Baculo_p24 PF05073.7 EPX74603.1 - 0.038 13.5 1.5 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 Baculovirus P24 capsid protein TPR_14 PF13428.1 EPX74603.1 - 0.057 14.0 4.1 0.52 11.0 0.0 3.9 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPX74603.1 - 0.072 12.7 7.7 0.84 9.3 0.2 3.5 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.12 EPX74603.1 - 0.079 12.9 6.5 4.7 7.3 0.3 4.5 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPX74603.1 - 0.17 12.2 5.9 0.63 10.4 0.1 4.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPX74603.1 - 0.39 10.6 0.1 0.39 10.6 0.1 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat PDZ_1 PF12812.2 EPX74604.1 - 1.3e-40 137.1 0.0 2.9e-30 103.9 0.0 2.9 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EPX74604.1 - 1.7e-14 53.4 1.1 4.6e-06 26.4 0.0 3.7 3 0 0 3 3 3 3 PDZ domain Trypsin_2 PF13365.1 EPX74604.1 - 1.4e-13 50.9 0.1 1.8e-11 44.0 0.0 2.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EPX74604.1 - 1e-07 32.0 0.8 0.059 13.5 0.0 4.0 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Peptidase_S7 PF00949.16 EPX74604.1 - 0.00078 18.8 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Tricorn_PDZ PF14685.1 EPX74604.1 - 0.0012 18.5 0.2 0.55 10.0 0.0 2.9 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S3 PF00944.14 EPX74604.1 - 0.035 13.5 0.2 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Alphavirus core protein DUF31 PF01732.11 EPX74604.1 - 0.045 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) DAO PF01266.19 EPX74604.1 - 0.11 11.4 0.0 8.7 5.1 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Peptidase_S46 PF10459.4 EPX74604.1 - 0.16 10.3 0.1 0.3 9.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase S46 YEATS PF03366.11 EPX74606.1 - 4.4e-12 45.5 0.3 1e-11 44.3 0.2 1.7 1 1 0 1 1 1 1 YEATS family Abhydrolase_6 PF12697.2 EPX74607.1 - 2.1e-29 103.0 0.0 2.6e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPX74607.1 - 4.1e-18 65.7 0.2 3.4e-16 59.5 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPX74607.1 - 3.5e-14 52.7 0.0 6e-14 52.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPX74607.1 - 2.1e-07 30.7 0.0 2.3e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein DUF2048 PF09752.4 EPX74607.1 - 3.3e-05 22.9 0.0 8.1e-05 21.6 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Esterase PF00756.15 EPX74607.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF676 PF05057.9 EPX74607.1 - 0.00063 19.0 0.8 0.0052 16.1 0.3 2.3 1 1 1 2 2 2 1 Putative serine esterase (DUF676) Chlorophyllase PF07224.6 EPX74607.1 - 0.0011 17.8 0.0 0.0049 15.7 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 EPX74607.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydro_lipase PF04083.11 EPX74607.1 - 0.0025 17.1 0.0 0.0055 16.0 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Acyl_transf_1 PF00698.16 EPX74607.1 - 0.021 14.1 0.1 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase domain PAF-AH_p_II PF03403.8 EPX74607.1 - 0.026 12.8 0.7 0.23 9.6 0.2 2.3 2 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Thioesterase PF00975.15 EPX74607.1 - 0.042 14.0 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.2 EPX74607.1 - 0.046 12.6 0.0 0.15 10.9 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF915 PF06028.6 EPX74607.1 - 0.056 12.5 0.0 0.4 9.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_S3Ae PF01015.13 EPX74608.1 - 8.2e-78 260.1 5.1 9.9e-78 259.9 3.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF4168 PF13767.1 EPX74608.1 - 0.24 12.0 2.0 0.36 11.4 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) Fasciclin PF02469.17 EPX74609.1 - 2.1e-26 92.3 0.4 1.3e-06 28.4 0.0 5.3 5 1 0 5 5 5 4 Fasciclin domain RNA_pol_L_2 PF13656.1 EPX74610.1 - 8.3e-32 108.4 0.0 1.1e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EPX74610.1 - 2.4e-12 45.7 0.0 3.2e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Abi PF02517.11 EPX74611.1 - 3.7e-13 49.4 13.4 3.7e-13 49.4 9.3 2.4 2 1 0 2 2 2 1 CAAX protease self-immunity Rep_fac_C PF08542.6 EPX74612.1 - 2e-18 66.1 0.0 4.3e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPX74612.1 - 2.5e-13 49.9 0.0 4.3e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EPX74612.1 - 9e-12 45.3 0.0 1.8e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EPX74612.1 - 9.6e-07 28.7 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPX74612.1 - 8.4e-06 24.9 0.0 6.8e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EPX74612.1 - 1.1e-05 25.6 0.2 0.003 17.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EPX74612.1 - 2.9e-05 23.6 0.0 4.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EPX74612.1 - 9.6e-05 22.0 0.0 0.00022 20.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EPX74612.1 - 0.0001 21.1 0.0 0.046 12.4 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 EPX74612.1 - 0.00019 21.0 0.4 0.051 13.0 0.2 2.3 1 1 1 2 2 2 2 AAA-like domain AAA_16 PF13191.1 EPX74612.1 - 0.00019 21.4 0.0 0.0036 17.3 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.8 EPX74612.1 - 0.00069 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 EPX74612.1 - 0.00078 18.6 0.0 0.013 14.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EPX74612.1 - 0.0012 18.4 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EPX74612.1 - 0.0013 18.4 0.2 0.022 14.4 0.1 2.3 1 1 0 2 2 2 1 NTPase ArgK PF03308.11 EPX74612.1 - 0.0032 16.2 0.1 0.0098 14.6 0.0 1.9 2 0 0 2 2 2 1 ArgK protein AAA_19 PF13245.1 EPX74612.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EPX74612.1 - 0.025 14.0 0.2 0.081 12.3 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EPX74612.1 - 0.056 13.7 0.0 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EPX74612.1 - 0.068 12.8 0.5 1.4 8.6 0.2 3.1 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 EPX74612.1 - 0.08 12.4 0.1 1 8.8 0.0 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase NB-ARC PF00931.17 EPX74612.1 - 0.55 9.0 2.8 0.83 8.4 0.5 2.0 1 1 1 2 2 2 0 NB-ARC domain MCM_bind PF09739.4 EPX74613.1 - 4.3e-20 71.4 0.0 7.4e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 EPX74613.1 - 1.3e-19 70.3 0.7 3.3e-19 69.0 0.5 1.8 1 0 0 1 1 1 1 Putative alanine racemase MCM PF00493.18 EPX74613.1 - 0.027 13.2 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family PINIT PF14324.1 EPX74614.1 - 9.1e-34 116.5 0.1 1.7e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EPX74614.1 - 2.3e-23 81.4 5.0 4.7e-23 80.4 3.4 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EPX74614.1 - 5.1e-10 38.6 0.1 1.4e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.3 EPX74614.1 - 1.4e-08 34.0 1.5 3.5e-08 32.8 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ribosomal_L28e PF01778.12 EPX74615.1 - 3e-34 117.8 0.2 3.5e-34 117.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.5 EPX74616.1 - 5.1e-37 126.5 0.1 7.6e-37 125.9 0.1 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) FliJ PF02050.11 EPX74618.1 - 0.052 13.5 9.8 0.17 11.9 1.7 3.7 2 1 0 3 3 3 0 Flagellar FliJ protein Spb1_C PF07780.7 EPX74619.1 - 1.8e-72 243.3 24.2 1.8e-72 243.3 16.8 4.0 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.14 EPX74619.1 - 1.1e-52 178.6 0.0 2.3e-52 177.5 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EPX74619.1 - 7.3e-49 165.3 7.9 7.3e-49 165.3 5.5 5.1 3 1 1 4 4 4 1 Domain of unknown function (DUF3381) Coq4 PF05019.8 EPX74620.1 - 1.1e-96 321.9 0.0 1.3e-96 321.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 JAB PF01398.16 EPX74621.1 - 1.4e-32 111.8 0.2 2.6e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EPX74621.1 - 7.2e-08 31.9 0.0 1.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain FAM86 PF14904.1 EPX74621.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function EF-hand_7 PF13499.1 EPX74622.1 - 6.4e-09 35.8 1.2 8.3e-09 35.4 0.8 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EPX74622.1 - 7.9e-09 34.1 0.1 5.1e-06 25.4 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EPX74622.1 - 1.4e-07 30.7 1.4 9.3e-06 25.1 0.2 2.7 2 1 1 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 EPX74622.1 - 3.5e-07 29.7 3.1 3.5e-06 26.5 0.1 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPX74622.1 - 4.8e-06 25.6 0.2 0.0022 17.2 0.2 2.2 2 0 0 2 2 2 2 EF hand TerB PF05099.8 EPX74622.1 - 0.04 13.6 0.1 0.049 13.3 0.1 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB TCO89 PF10452.4 EPX74623.1 - 0.047 12.5 1.4 0.049 12.5 1.0 1.0 1 0 0 1 1 1 0 TORC1 subunit TCO89 DUF884 PF05959.6 EPX74623.1 - 0.065 12.5 0.1 0.071 12.4 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) Pkinase PF00069.20 EPX74624.1 - 4.4e-64 216.1 0.0 5.2e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74624.1 - 7.8e-24 84.1 0.0 1.1e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX74624.1 - 9.7e-07 28.0 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPX74624.1 - 0.00035 20.3 0.1 0.0043 16.8 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPX74624.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FA_hydroxylase PF04116.8 EPX74625.1 - 1.3e-13 51.3 24.0 1.1e-12 48.3 14.0 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily DER1 PF04511.10 EPX74626.1 - 1.6e-33 115.8 12.6 1.9e-33 115.6 8.7 1.0 1 0 0 1 1 1 1 Der1-like family Cohesin_load PF10345.4 EPX74627.1 - 1.1e-74 251.7 21.8 4.5e-74 249.7 15.1 1.7 1 1 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.1 EPX74627.1 - 3.6e-08 33.2 5.0 0.53 10.2 0.0 5.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EPX74627.1 - 0.0033 17.0 0.4 2.6 8.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPX74627.1 - 0.0063 16.2 1.0 3.8 7.5 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPX74627.1 - 0.0079 15.8 0.1 10 5.8 0.0 3.9 3 0 0 3 3 3 1 TPR repeat TPR_10 PF13374.1 EPX74627.1 - 0.014 15.2 0.2 0.7 9.9 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPX74627.1 - 0.025 14.2 1.1 8.3 6.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TGT PF01702.13 EPX74628.1 - 1.7e-87 292.6 0.1 2.1e-87 292.3 0.1 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase CENP-I PF07778.6 EPX74629.1 - 2.4e-75 253.6 11.5 4.2e-75 252.8 7.9 1.3 1 0 0 1 1 1 1 Mis6 His_Phos_1 PF00300.17 EPX74630.1 - 7.1e-30 104.1 0.0 9.7e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PUF PF00806.14 EPX74631.1 - 3.9e-64 208.6 20.0 9.4e-08 31.1 0.2 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MgtE_N PF03448.12 EPX74631.1 - 0.042 14.1 0.6 5.6 7.3 0.0 3.4 3 1 0 3 3 3 0 MgtE intracellular N domain zf-Tim10_DDP PF02953.10 EPX74633.1 - 3e-22 77.6 1.8 3.5e-22 77.4 1.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EPX74633.1 - 0.021 14.2 1.1 0.073 12.5 0.7 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) YL1_C PF08265.6 EPX74635.1 - 1.5e-18 65.9 1.7 1.6e-17 62.7 0.5 2.3 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Ribosomal_L28e PF01778.12 EPX74636.1 - 2.9e-30 105.0 1.5 3.5e-30 104.8 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EPX74636.1 - 2.2e-28 98.2 14.7 2.2e-28 98.2 10.2 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region PYC_OADA PF02436.13 EPX74636.1 - 0.092 12.1 0.7 0.17 11.3 0.5 1.6 1 0 0 1 1 1 0 Conserved carboxylase domain SDA1 PF05285.7 EPX74636.1 - 0.11 11.7 21.7 0.17 11.1 15.1 1.4 1 0 0 1 1 1 0 SDA1 SMN PF06003.7 EPX74636.1 - 0.19 10.7 4.8 0.32 10.0 3.3 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Daxx PF03344.10 EPX74636.1 - 4.1 5.7 21.8 5.3 5.4 15.1 1.1 1 0 0 1 1 1 0 Daxx Family DUF2462 PF09495.5 EPX74636.1 - 6 7.6 7.5 0.71 10.6 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2462) TrmE_N PF10396.4 EPX74637.1 - 2.2e-39 133.9 0.0 5.5e-39 132.6 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 EPX74637.1 - 4.2e-19 68.6 0.2 1.4e-18 66.9 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 EPX74637.1 - 9e-18 64.4 0.1 9.9e-17 61.1 0.0 2.8 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 EPX74637.1 - 9.3e-10 37.9 0.2 1.5e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPX74637.1 - 1.2e-06 28.4 0.0 8.1e-05 22.4 0.0 2.8 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 EPX74637.1 - 0.0002 21.8 0.0 0.00049 20.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 EPX74637.1 - 0.0003 21.5 0.0 0.0013 19.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPX74637.1 - 0.0022 17.9 0.0 0.0048 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPX74637.1 - 0.0063 16.8 0.4 0.05 13.8 0.2 2.5 2 1 0 2 2 2 1 ABC transporter Arf PF00025.16 EPX74637.1 - 0.0073 15.5 0.2 1.7 7.8 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF258 PF03193.11 EPX74637.1 - 0.008 15.3 0.0 0.032 13.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPX74637.1 - 0.044 13.9 0.1 0.58 10.3 0.0 2.7 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EPX74637.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Alkyl_sulf_C PF14864.1 EPX74637.1 - 0.051 13.5 0.1 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal DnaB_2 PF07261.6 EPX74637.1 - 0.057 13.0 0.0 12 5.5 0.0 2.7 2 0 0 2 2 2 0 Replication initiation and membrane attachment cobW PF02492.14 EPX74637.1 - 0.065 12.6 0.1 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 EPX74637.1 - 0.073 12.4 0.1 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 EPX74637.1 - 0.084 12.5 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EPX74637.1 - 0.093 12.9 0.0 0.91 9.7 0.0 2.5 3 0 0 3 3 3 0 RNA helicase Pkinase PF00069.20 EPX74638.1 - 1.1e-36 126.2 0.0 1.5e-23 83.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74638.1 - 7.2e-16 58.0 0.0 2.1e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase NYD-SP28_assoc PF14775.1 EPX74638.1 - 0.39 10.4 2.4 0.88 9.3 1.7 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain SNO PF01174.14 EPX74639.1 - 2.5e-44 151.1 0.0 2.9e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EPX74639.1 - 8.5e-08 31.9 0.1 1.3e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EPX74639.1 - 3e-06 26.8 0.0 7.9e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPX74639.1 - 4e-05 23.1 0.0 0.00068 19.1 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 Peptidase_S51 PF03575.12 EPX74639.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 RRM_5 PF13893.1 EPX74640.1 - 9.6e-06 25.3 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX74640.1 - 1.9e-05 24.1 0.0 3.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74640.1 - 0.0003 20.7 0.0 0.0005 20.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LRR_3 PF07725.7 EPX74641.1 - 2.3 8.1 0.0 2.3 8.1 0.0 2.8 3 0 0 3 3 3 0 Leucine Rich Repeat Coprogen_oxidas PF01218.13 EPX74642.1 - 1.7e-124 414.1 0.2 2e-124 413.9 0.2 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase ATP-synt_ab PF00006.20 EPX74644.1 - 4.6e-63 212.5 0.0 7.1e-63 211.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPX74644.1 - 5.3e-27 94.5 1.2 9.9e-27 93.6 0.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPX74644.1 - 3.7e-22 78.2 0.4 1.6e-21 76.2 0.3 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 EPX74644.1 - 0.0011 18.3 0.0 0.077 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EPX74644.1 - 0.0021 17.2 0.1 0.004 16.2 0.1 1.5 1 0 0 1 1 1 1 KaiC MobB PF03205.9 EPX74644.1 - 0.017 14.8 0.2 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EPX74644.1 - 0.026 14.1 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 EPX74644.1 - 0.033 13.3 0.0 0.069 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EPX74644.1 - 0.04 13.6 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 EPX74644.1 - 0.067 13.3 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 EPX74644.1 - 0.081 12.9 0.3 0.63 9.9 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain NB-ARC PF00931.17 EPX74644.1 - 0.1 11.4 0.9 0.3 9.9 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 EPX74644.1 - 0.11 12.7 0.1 3 8.0 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) 6PF2K PF01591.13 EPX74645.1 - 1.4e-64 217.2 0.1 2.2e-64 216.5 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EPX74645.1 - 1.9e-21 76.7 0.0 7.2e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EPX74645.1 - 1.5e-05 25.7 0.0 3.8e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPX74645.1 - 0.00045 20.1 0.0 0.0018 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPX74645.1 - 0.013 15.7 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPX74645.1 - 0.066 13.1 0.1 0.43 10.4 0.0 2.2 1 1 0 2 2 2 0 AAA domain RHD3 PF05879.7 EPX74646.1 - 3.6e-252 838.5 9.9 3.2e-251 835.4 6.8 1.9 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EPX74646.1 - 2.3e-07 30.1 0.3 4.8e-07 29.0 0.2 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EPX74646.1 - 1.5e-06 28.1 0.0 4.6e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPX74646.1 - 1.6e-05 24.8 0.0 3.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EPX74646.1 - 0.00072 20.0 0.0 0.0031 17.9 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EPX74646.1 - 0.019 14.9 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EPX74646.1 - 0.063 12.5 0.1 0.16 11.2 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B TBPIP PF07106.8 EPX74647.1 - 3.2e-48 163.4 7.5 4e-48 163.1 5.2 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 EPX74647.1 - 1.5e-06 27.9 3.4 2.4e-06 27.3 2.4 1.4 1 0 0 1 1 1 1 Mnd1 family Seryl_tRNA_N PF02403.17 EPX74647.1 - 0.0039 17.1 2.0 0.0039 17.1 1.4 2.8 2 2 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF1409 PF07197.7 EPX74647.1 - 0.047 13.7 0.8 0.16 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) BCNT PF07572.7 EPX74647.1 - 0.073 13.0 0.8 0.44 10.5 0.5 2.3 1 1 0 1 1 1 0 Bucentaur or craniofacial development DivIC PF04977.10 EPX74647.1 - 0.082 12.3 3.2 2.4 7.6 0.2 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF1192 PF06698.6 EPX74647.1 - 0.1 12.4 0.0 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Cep57_MT_bd PF06657.8 EPX74647.1 - 0.12 12.3 2.1 0.29 11.0 0.9 2.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 HutP PF09021.6 EPX74647.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 HutP PspA_IM30 PF04012.7 EPX74647.1 - 0.21 10.9 6.4 3.8 6.8 4.4 2.6 1 1 0 1 1 1 0 PspA/IM30 family IncA PF04156.9 EPX74647.1 - 0.29 10.6 8.0 1.6 8.2 5.5 2.0 1 1 1 2 2 2 0 IncA protein DUF972 PF06156.8 EPX74647.1 - 0.31 11.4 4.6 3.7 7.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF972) FlxA PF14282.1 EPX74647.1 - 0.46 10.4 12.0 0.045 13.6 4.6 2.0 2 1 0 2 2 2 0 FlxA-like protein HR1 PF02185.11 EPX74647.1 - 0.48 10.2 7.4 1.9 8.2 0.2 3.4 3 1 0 3 3 3 0 Hr1 repeat YlqD PF11068.3 EPX74647.1 - 2.8 7.9 7.7 1.6 8.7 2.2 2.3 1 1 1 2 2 2 0 YlqD protein Tropomyosin_1 PF12718.2 EPX74647.1 - 2.8 7.7 9.2 1.8 8.4 2.9 2.3 2 1 1 3 3 3 0 Tropomyosin like Syntaxin PF00804.20 EPX74647.1 - 3.1 8.0 8.7 0.84 9.8 2.6 2.1 1 1 1 2 2 2 0 Syntaxin DUF2681 PF10883.3 EPX74647.1 - 8.9 6.5 10.1 21 5.4 0.2 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF2681) PAP_assoc PF03828.14 EPX74650.1 - 8.2e-18 64.1 0.7 8.6e-17 60.8 0.3 2.5 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPX74650.1 - 1e-06 28.9 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain OAS1_C PF10421.4 EPX74650.1 - 0.019 14.4 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus JAB PF01398.16 EPX74651.1 - 2.6e-06 27.1 0.1 5.4e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Dec-1 PF04624.9 EPX74651.1 - 0.2 11.2 4.4 0.44 10.2 3.1 1.4 1 0 0 1 1 1 0 Dec-1 repeat Septin PF00735.13 EPX74652.1 - 1.4e-112 375.3 1.1 1.6e-112 375.1 0.8 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EPX74652.1 - 7.2e-10 38.8 0.0 4e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPX74652.1 - 2.4e-06 27.1 0.2 6e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EPX74652.1 - 6.2e-06 25.4 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EPX74652.1 - 1.6e-05 24.5 0.1 1.6e-05 24.5 0.1 1.3 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 EPX74652.1 - 1.7e-05 25.1 0.2 4e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EPX74652.1 - 1.9e-05 24.7 0.0 3.6e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 EPX74652.1 - 4.5e-05 23.3 1.5 0.041 13.6 0.2 2.5 1 1 0 2 2 2 2 Dynamin family AIG1 PF04548.11 EPX74652.1 - 6.3e-05 22.1 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_14 PF13173.1 EPX74652.1 - 0.00012 21.9 0.0 0.00038 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EPX74652.1 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EPX74652.1 - 0.00023 21.9 1.5 0.0057 17.4 1.0 2.4 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EPX74652.1 - 0.00025 20.0 0.0 0.00043 19.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Gtr1_RagA PF04670.7 EPX74652.1 - 0.00027 20.1 0.2 0.0013 17.9 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EPX74652.1 - 0.00029 21.3 0.0 0.0021 18.5 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EPX74652.1 - 0.00034 20.1 0.0 0.00063 19.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.1 EPX74652.1 - 0.00046 20.0 0.0 0.00092 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPX74652.1 - 0.0011 19.0 0.0 0.0032 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain GBP PF02263.14 EPX74652.1 - 0.0027 16.7 0.0 0.0061 15.6 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.1 EPX74652.1 - 0.0029 17.5 0.1 0.15 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EPX74652.1 - 0.0044 16.7 0.0 0.0088 15.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EPX74652.1 - 0.0054 17.0 0.1 0.0081 16.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EPX74652.1 - 0.0059 15.8 0.2 0.03 13.5 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RNA_helicase PF00910.17 EPX74652.1 - 0.0059 16.7 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase ATP_bind_1 PF03029.12 EPX74652.1 - 0.011 15.3 0.1 0.062 12.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 EPX74652.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.16 EPX74652.1 - 0.017 14.5 0.0 0.075 12.4 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase PduV-EutP PF10662.4 EPX74652.1 - 0.018 14.5 0.1 0.16 11.4 0.0 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EPX74652.1 - 0.019 15.2 0.6 0.073 13.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 EPX74652.1 - 0.03 13.0 0.0 0.046 12.4 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DUF815 PF05673.8 EPX74652.1 - 0.035 13.0 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Adeno_IVa2 PF02456.10 EPX74652.1 - 0.044 12.4 0.1 0.11 11.0 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein cobW PF02492.14 EPX74652.1 - 0.044 13.2 0.1 0.11 11.8 0.0 1.8 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EPX74652.1 - 0.05 13.2 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 1 0 Archaeal ATPase AAA_24 PF13479.1 EPX74652.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPX74652.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain IIGP PF05049.8 EPX74652.1 - 0.057 12.2 0.4 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) SMC_N PF02463.14 EPX74652.1 - 0.067 12.4 0.3 0.13 11.5 0.2 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.17 EPX74652.1 - 0.073 11.9 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.21 EPX74652.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Ras PF00071.17 EPX74652.1 - 0.091 12.1 0.0 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 Ras family Zn_clus PF00172.13 EPX74653.1 - 1.4e-09 37.7 10.0 2.9e-09 36.7 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EPX74654.1 - 4.8e-26 89.6 10.9 4.3e-08 32.7 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EPX74654.1 - 8.7e-08 32.1 0.5 0.00032 20.4 0.2 2.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 EPX74654.1 - 0.038 13.7 8.0 3.5 7.2 0.1 3.7 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Glyco_hydro_81 PF03639.8 EPX74655.1 - 6.5e-189 629.3 16.6 8.2e-189 628.9 11.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Carb_bind PF10645.4 EPX74655.1 - 8e-58 192.0 49.4 7.6e-23 80.0 10.3 3.4 3 0 0 3 3 3 3 Carbohydrate binding IGFL PF14653.1 EPX74655.1 - 0.66 10.0 30.9 13 5.9 0.1 6.1 3 2 2 5 5 5 0 Insulin growth factor-like family Sod_Cu PF00080.15 EPX74656.1 - 3.2e-46 157.0 6.1 3.8e-46 156.7 4.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF2553 PF10830.3 EPX74656.1 - 0.13 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2553) Aldedh PF00171.17 EPX74657.1 - 1.4e-21 76.4 0.5 7.2e-16 57.5 0.1 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Pkinase PF00069.20 EPX74658.1 - 1.5e-57 194.7 0.0 3.3e-38 131.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74658.1 - 6.8e-26 90.8 0.0 1.9e-19 69.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EPX74658.1 - 0.00013 21.1 0.1 0.00036 19.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPX74658.1 - 0.00013 20.9 0.0 0.00026 20.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 EPX74658.1 - 0.0021 18.5 0.2 0.0043 17.5 0.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EPX74658.1 - 0.0053 16.5 0.2 0.068 12.8 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPX74658.1 - 0.015 14.1 0.0 0.078 11.7 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EPX74658.1 - 0.052 12.3 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase E1-E2_ATPase PF00122.15 EPX74659.1 - 5.3e-20 71.4 0.0 5.3e-20 71.4 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EPX74659.1 - 1.6e-12 48.2 1.0 4.8e-08 33.6 0.2 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPX74659.1 - 4.6e-12 45.7 0.0 1.5e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPX74659.1 - 1.6e-11 44.7 0.2 1.1e-10 42.0 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPX74659.1 - 0.00043 19.9 0.1 0.0013 18.3 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MKT1_C PF12246.3 EPX74660.1 - 1.2e-22 80.0 3.0 1.7e-22 79.6 2.1 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EPX74660.1 - 2.2e-14 53.4 0.1 3.8e-12 46.3 0.0 2.9 2 1 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EPX74660.1 - 1.6e-08 34.4 0.0 3.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EPX74660.1 - 1.4e-07 31.7 0.0 3.5e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain Mito_carr PF00153.22 EPX74661.1 - 2.9e-57 190.3 2.3 4.5e-18 64.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 EPX74662.1 - 1.1e-23 83.3 1.4 1.8e-23 82.7 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX74662.1 - 1.3e-09 37.7 10.8 2.1e-09 37.1 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 EPX74663.1 - 2.3e-38 132.0 0.0 4.2e-22 78.5 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPX74663.1 - 0.0027 17.8 0.0 0.22 11.5 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPX74663.1 - 0.0032 17.3 0.3 0.06 13.2 0.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPX74663.1 - 0.014 15.1 0.0 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EPX74663.1 - 0.016 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPX74663.1 - 0.028 13.3 0.2 0.41 9.4 0.0 2.2 2 1 1 3 3 3 0 Lycopene cyclase protein GIDA PF01134.17 EPX74663.1 - 0.028 13.2 0.0 0.093 11.5 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EPX74663.1 - 0.096 12.9 0.0 0.33 11.2 0.0 1.9 1 1 1 2 2 2 0 Putative NAD(P)-binding Aldedh PF00171.17 EPX74664.1 - 3.2e-153 510.4 0.1 3.6e-153 510.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Hat1_N PF10394.4 EPX74665.1 - 2.2e-20 73.3 0.4 3.5e-19 69.4 0.3 2.3 1 1 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 EPX74665.1 - 0.0092 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EPX74665.1 - 0.012 14.8 0.3 0.021 14.0 0.2 1.4 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_7 PF13508.1 EPX74665.1 - 0.023 14.8 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1900 PF08954.6 EPX74666.1 - 9.5e-51 170.8 0.0 3.8e-50 168.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) WD40 PF00400.27 EPX74666.1 - 2e-27 94.0 4.4 4.9e-10 38.9 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF1899 PF08953.6 EPX74666.1 - 5.6e-13 48.3 0.1 1.1e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) DUF3635 PF12330.3 EPX74667.1 - 8.1e-20 70.7 1.2 1.5e-19 69.8 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3635) Ish1 PF10281.4 EPX74669.1 - 5e-29 100.0 10.3 5.7e-12 45.4 0.0 7.0 6 1 0 6 6 6 5 Putative stress-responsive nuclear envelope protein SAM_2 PF07647.12 EPX74669.1 - 0.0011 18.7 3.0 5.3 6.9 0.0 4.3 4 0 0 4 4 4 2 SAM domain (Sterile alpha motif) SAP PF02037.22 EPX74669.1 - 0.0026 17.2 0.0 3.8 7.1 0.0 3.5 3 1 0 3 3 3 2 SAP domain Sin3_corepress PF08295.7 EPX74669.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Sin3 family co-repressor Methyltransf_16 PF10294.4 EPX74670.1 - 5.7e-48 162.6 0.1 8.1e-48 162.1 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EPX74670.1 - 2.8e-06 26.8 0.0 4.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EPX74670.1 - 5.3e-06 26.9 0.0 8.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX74670.1 - 2.8e-05 23.8 0.0 4.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX74670.1 - 0.00032 20.3 0.0 0.00054 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX74670.1 - 0.00047 20.5 0.0 0.00089 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EPX74670.1 - 0.035 13.6 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.8 EPX74670.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ras PF00071.17 EPX74672.1 - 1.1e-54 184.1 0.0 1.3e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX74672.1 - 1.3e-17 64.3 0.0 1.7e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX74672.1 - 3e-10 39.5 0.0 4.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPX74672.1 - 0.00038 19.6 0.0 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPX74672.1 - 0.0021 18.0 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPX74672.1 - 0.0078 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EPX74672.1 - 0.015 14.7 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EPX74672.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter dsDNA_bind PF01984.15 EPX74673.1 - 7e-31 106.3 14.8 8.1e-31 106.1 10.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF3069 PF11269.3 EPX74673.1 - 0.12 12.4 0.7 0.34 10.9 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3069) SDA1 PF05285.7 EPX74673.1 - 1.8 7.7 10.4 0.18 11.0 2.8 1.9 2 0 0 2 2 2 0 SDA1 Sec2p PF06428.6 EPX74674.1 - 1.6e-25 88.9 5.1 1.6e-25 88.9 3.5 2.3 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF745 PF05335.8 EPX74674.1 - 0.33 10.4 10.6 0.42 10.1 6.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) IncA PF04156.9 EPX74674.1 - 7.4 6.1 22.3 16 5.0 15.5 1.6 1 0 0 1 1 1 0 IncA protein ATP-synt_J PF04911.7 EPX74675.1 - 3.1e-16 58.5 0.1 3.7e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase j chain Pkinase PF00069.20 EPX74676.1 - 2.7e-39 134.9 0.0 3.4e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74676.1 - 2.9e-16 59.3 0.0 3.5e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX74676.1 - 2.5e-05 24.1 0.0 0.00066 19.4 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPX74676.1 - 0.0071 15.1 0.3 0.011 14.6 0.2 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 EPX74676.1 - 0.038 13.5 0.1 0.073 12.6 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 EPX74676.1 - 0.062 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like SNARE PF05739.14 EPX74677.1 - 2.4e-10 39.9 0.1 3.2e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EPX74677.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 Syntaxin_2 PF14523.1 EPX74677.1 - 0.0068 16.4 1.2 0.009 16.0 0.8 1.1 1 0 0 1 1 1 1 Syntaxin-like protein Syntaxin PF00804.20 EPX74677.1 - 0.038 14.1 0.2 0.048 13.8 0.1 1.1 1 0 0 1 1 1 0 Syntaxin Sec20 PF03908.8 EPX74677.1 - 0.062 13.0 0.2 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 Sec20 DUF3904 PF13044.1 EPX74677.1 - 0.064 11.6 0.1 0.066 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3904) Corona_S2 PF01601.11 EPX74677.1 - 0.077 11.0 0.2 0.089 10.8 0.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DASH_Duo1 PF08651.5 EPX74677.1 - 0.08 12.5 0.9 0.28 10.7 0.3 1.8 1 1 1 2 2 2 0 DASH complex subunit Duo1 Glyco_trans_1_4 PF13692.1 EPX74678.1 - 2.3e-19 69.8 0.0 8.1e-19 68.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EPX74678.1 - 2.6e-11 43.2 0.0 1.6e-09 37.4 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EPX74678.1 - 1.1e-06 28.8 0.0 2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EPX74678.1 - 2.1e-06 27.9 0.0 5.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 RNA_pol_Rpb5_C PF01191.14 EPX74679.1 - 3.1e-35 119.5 0.6 2.4e-34 116.7 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EPX74679.1 - 3.6e-26 91.4 0.0 5.8e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EPX74679.1 - 0.0037 17.0 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease DUF4480 PF13715.1 EPX74679.1 - 0.099 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) Lipase_3 PF01764.20 EPX74680.1 - 4.5e-08 32.8 0.0 1.8e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EPX74680.1 - 0.037 13.7 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Coat_F PF07875.7 EPX74680.1 - 0.06 13.4 0.1 5.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Coat F domain Nol1_Nop2_Fmu PF01189.12 EPX74681.1 - 1.5e-33 116.4 0.0 2.4e-16 59.9 0.0 4.8 2 2 2 4 4 4 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EPX74681.1 - 0.0035 17.3 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain BRCT PF00533.21 EPX74682.1 - 9.1e-42 141.0 5.7 4.1e-15 55.6 0.0 4.5 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EPX74682.1 - 1e-40 137.3 3.8 6.5e-19 67.5 0.0 4.5 4 1 0 4 4 4 3 twin BRCT domain CTD PF12815.2 EPX74683.1 - 2.3e-29 102.2 55.3 2.7e-20 73.0 20.9 2.8 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 EPX74683.1 - 2.7e-28 97.5 0.1 5.5e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EPX74683.1 - 2.1e-16 60.2 12.3 2.1e-16 60.2 8.5 3.5 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EPX74683.1 - 4.9e-14 51.3 22.7 1.2e-07 31.1 0.4 5.2 5 0 0 5 5 5 3 KOW motif GEMIN8 PF15348.1 EPX74683.1 - 4.1 7.3 24.9 7.9 6.4 17.3 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 zf-C2HC5 PF06221.8 EPX74684.1 - 4.8e-22 77.4 6.8 8.4e-22 76.6 4.7 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type PH_BEACH PF14844.1 EPX74684.1 - 0.032 14.0 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH PQQ_3 PF13570.1 EPX74685.1 - 5.2e-05 23.3 0.1 2.8 8.3 0.0 3.9 3 0 0 3 3 3 2 PQQ-like domain WD40 PF00400.27 EPX74685.1 - 9e-05 22.2 8.6 0.035 14.0 0.1 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Nop14 PF04147.7 EPX74685.1 - 0.16 9.9 12.3 0.21 9.4 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EPX74685.1 - 0.21 10.6 14.8 0.31 10.0 10.3 1.1 1 0 0 1 1 1 0 BUD22 Herpes_DNAp_acc PF04929.7 EPX74685.1 - 0.32 9.9 3.3 0.46 9.4 2.3 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Nucleoplasmin PF03066.10 EPX74685.1 - 0.47 9.9 6.9 0.97 8.9 4.8 1.6 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EPX74685.1 - 0.66 7.9 11.5 0.98 7.3 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 EPX74685.1 - 5.4 4.6 14.3 24 2.5 8.2 2.2 2 0 0 2 2 2 0 DNA polymerase phi PLA2_B PF01735.13 EPX74686.1 - 6.4e-199 661.1 2.0 8.5e-199 660.7 1.4 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.16 EPX74686.1 - 0.03 14.1 3.1 0.072 12.9 2.2 1.5 1 0 0 1 1 1 0 IBR domain PLA2_B PF01735.13 EPX74687.1 - 1.7e-174 580.6 5.7 2e-174 580.4 3.9 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF3336 PF11815.3 EPX74688.1 - 1.7e-39 134.6 0.4 2.5e-39 134.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EPX74688.1 - 3.6e-24 85.8 0.0 6.3e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Peptidase_S51 PF03575.12 EPX74688.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S51 Lambda_CIII PF02061.11 EPX74688.1 - 0.13 12.2 0.9 21 5.1 0.4 3.2 2 1 1 3 3 3 0 Lambda Phage CIII SPATIAL PF15256.1 EPX74691.1 - 0.12 12.4 2.5 0.18 11.8 1.4 1.5 1 1 0 1 1 1 0 SPATIAL SprA-related PF12118.3 EPX74691.1 - 0.12 11.6 3.3 0.18 11.1 2.3 1.2 1 0 0 1 1 1 0 SprA-related family TRAM_LAG1_CLN8 PF03798.11 EPX74692.1 - 2.9e-35 121.6 31.0 2.9e-35 121.6 21.5 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EPX74692.1 - 8.2e-16 57.2 0.3 8.2e-16 57.2 0.2 2.6 3 0 0 3 3 3 1 TRAM1-like protein ThiF PF00899.16 EPX74693.1 - 6e-38 129.7 0.0 1.1e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 EPX74693.1 - 0.00019 20.5 0.0 0.00036 19.6 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EPX74693.1 - 0.017 14.5 0.1 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EPX74693.1 - 0.047 12.6 0.1 0.15 10.9 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 EPX74693.1 - 0.047 13.1 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MRJP PF03022.11 EPX74693.1 - 0.098 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Major royal jelly protein Med21 PF11221.3 EPX74693.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Subunit 21 of Mediator complex 3HCDH_N PF02737.13 EPX74693.1 - 0.13 11.9 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EPX74693.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain KH_3 PF13014.1 EPX74694.1 - 9.3e-06 25.1 0.1 0.0004 19.9 0.0 2.4 2 0 0 2 2 2 1 KH domain KH_1 PF00013.24 EPX74694.1 - 1.6e-05 24.4 0.0 0.00014 21.3 0.0 2.2 2 0 0 2 2 2 1 KH domain Sporozoite_P67 PF05642.6 EPX74694.1 - 0.017 13.0 0.3 0.025 12.4 0.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med3 PF11593.3 EPX74694.1 - 0.53 9.4 7.3 0.42 9.8 1.1 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal UQ_con PF00179.21 EPX74695.1 - 4.1e-47 159.1 0.0 4.6e-47 158.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPX74695.1 - 0.0014 18.4 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPX74695.1 - 0.049 13.5 0.8 0.068 13.0 0.6 1.7 1 1 0 1 1 1 0 RWD domain Ribosomal_L38e PF01781.13 EPX74696.1 - 7e-33 112.1 0.9 7.8e-33 112.0 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Alpha-mann_mid PF09261.6 EPX74696.1 - 0.048 13.8 0.0 0.056 13.6 0.0 1.1 1 0 0 1 1 1 0 Alpha mannosidase, middle domain HlyIII PF03006.15 EPX74697.1 - 1.5e-54 184.7 28.1 2e-54 184.3 19.5 1.2 1 0 0 1 1 1 1 Haemolysin-III related Arfaptin PF06456.8 EPX74697.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Arfaptin-like domain DUF3493 PF11998.3 EPX74697.1 - 0.17 11.7 1.8 0.46 10.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) EamA PF00892.15 EPX74697.1 - 0.42 10.6 17.5 0.099 12.6 5.2 2.6 1 1 1 2 2 2 0 EamA-like transporter family DUF373 PF04123.8 EPX74697.1 - 2.4 7.0 7.4 0.15 11.0 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Rad52_Rad22 PF04098.10 EPX74698.1 - 1.9e-59 199.8 0.0 3.1e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein MTHFR PF02219.12 EPX74699.1 - 3.4e-123 410.3 0.0 5e-123 409.7 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_8 PF05148.10 EPX74700.1 - 6.8e-89 297.2 0.0 8.3e-89 296.9 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EPX74700.1 - 6.8e-09 36.1 0.2 3e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPX74700.1 - 0.00035 19.7 0.0 0.018 14.1 0.0 2.2 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EPX74700.1 - 0.00044 20.0 0.0 0.00074 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX74700.1 - 0.00077 19.0 0.0 0.16 11.5 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX74700.1 - 0.007 16.7 0.1 0.14 12.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX74700.1 - 0.044 14.2 0.0 0.54 10.7 0.0 2.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EPX74700.1 - 0.051 13.2 0.5 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Neur_chan_memb PF02932.11 EPX74700.1 - 1.1 9.0 4.8 1.6 8.6 3.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.5 EPX74700.1 - 2.2 6.5 9.7 1.9 6.8 6.0 1.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup CPSF100_C PF13299.1 EPX74700.1 - 2.6 8.2 9.6 3.9 7.6 6.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Asp_protease PF09668.5 EPX74701.1 - 3.4e-60 201.0 0.1 4.9e-60 200.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EPX74701.1 - 3.4e-12 46.7 0.0 8.8e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EPX74701.1 - 3.9e-08 33.0 0.1 9.5e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 EPX74701.1 - 9.8e-06 25.2 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 EPX74701.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EPX74701.1 - 2.2e-05 24.2 0.0 8.5e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease DIE2_ALG10 PF04922.7 EPX74702.1 - 3.8e-103 345.4 31.9 4.7e-103 345.1 22.1 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family DUF1011 PF06237.7 EPX74702.1 - 0.0094 15.8 1.3 1 9.3 0.4 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1011) DUF2834 PF11196.3 EPX74702.1 - 0.034 14.2 1.1 0.034 14.2 0.8 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF2834) UbiA PF01040.13 EPX74703.1 - 2.6e-35 121.8 12.5 3.4e-35 121.5 8.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family GTP_EFTU PF00009.22 EPX74704.1 - 3.8e-33 114.5 0.0 2.5e-32 111.8 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EPX74704.1 - 1.8e-17 63.1 0.0 4.6e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EPX74704.1 - 1.6e-13 50.5 5.3 3.3e-08 33.5 0.1 3.2 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPX74704.1 - 1e-06 28.7 0.1 5.2e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EPX74704.1 - 0.0011 18.5 0.0 0.0078 15.7 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU_D4 PF14578.1 EPX74704.1 - 0.0021 17.6 0.4 0.0067 16.0 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 AAA_22 PF13401.1 EPX74704.1 - 0.0068 16.5 0.1 0.029 14.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPX74704.1 - 0.13 12.2 2.2 0.31 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 EPX74704.1 - 0.29 11.6 0.0 0.29 11.6 0.0 3.4 3 0 0 3 3 3 0 Miro-like protein AMP-binding PF00501.23 EPX74705.1 - 4.8e-48 163.5 0.0 3.3e-26 91.6 0.0 4.2 3 2 0 3 3 3 3 AMP-binding enzyme DEAD PF00270.24 EPX74706.1 - 2.4e-43 147.5 0.1 4.8e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX74706.1 - 1.5e-25 88.8 0.0 4.1e-25 87.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPX74706.1 - 0.056 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Nup_retrotrp_bd PF10599.4 EPX74707.1 - 2.7e-05 24.7 14.3 2.7e-05 24.7 9.9 10.8 2 2 6 8 8 8 1 Retro-transposon transporting motif Clat_adaptor_s PF01217.15 EPX74708.1 - 1e-53 180.8 0.4 1.2e-53 180.6 0.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Solute_trans_a PF03619.11 EPX74709.1 - 1.7e-83 280.0 8.0 2.1e-83 279.8 5.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha HhH-GPD PF00730.20 EPX74710.1 - 1.5e-18 67.0 0.0 3.1e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EPX74710.1 - 2.5e-08 33.1 0.0 5.4e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EPX74710.1 - 0.0066 16.5 0.0 0.48 10.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain PHD PF00628.24 EPX74711.1 - 6e-10 38.6 8.8 1e-09 37.9 6.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EPX74711.1 - 0.0049 16.1 4.6 0.025 13.9 2.8 2.3 1 1 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EPX74711.1 - 0.017 14.8 3.5 0.017 14.8 2.5 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EPX74711.1 - 0.08 12.2 5.4 0.08 12.2 1.8 2.1 1 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EPX74711.1 - 0.22 11.2 12.8 0.13 12.0 4.1 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CwfJ_C_1 PF04677.10 EPX74712.1 - 2.6e-38 130.4 0.0 5.2e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EPX74712.1 - 2.6e-21 75.9 0.8 9.2e-21 74.1 0.2 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 SPC22 PF04573.7 EPX74713.1 - 6.7e-47 158.9 3.4 7.5e-47 158.8 2.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit MVIN PF03023.9 EPX74713.1 - 0.018 13.4 0.0 0.024 13.0 0.0 1.1 1 0 0 1 1 1 0 MviN-like protein DUF2434 PF10361.4 EPX74714.1 - 3.5e-56 190.4 1.0 4.4e-56 190.1 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) HLH PF00010.21 EPX74715.1 - 9.7e-14 50.8 0.6 1.9e-13 49.8 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DRMBL PF07522.9 EPX74716.1 - 5.8e-27 93.9 0.0 1.3e-26 92.7 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EPX74716.1 - 1.3e-11 44.4 0.6 2.2e-11 43.6 0.4 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPX74716.1 - 6.2e-05 22.7 3.0 0.00011 21.8 2.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Ion_trans_N PF08412.5 EPX74716.1 - 0.11 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Ion transport protein N-terminal EDR1 PF14381.1 EPX74717.1 - 0.037 13.5 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 PCI PF01399.22 EPX74718.1 - 3.1e-07 30.6 0.3 1.3e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 PCI domain TPR_11 PF13414.1 EPX74718.1 - 0.36 10.4 4.9 0.25 10.9 0.5 2.7 2 1 0 2 2 2 0 TPR repeat TPR_12 PF13424.1 EPX74718.1 - 2.7 8.0 7.1 0.75 9.7 0.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Ribosomal_S8 PF00410.14 EPX74719.1 - 4.2e-27 94.5 0.1 5.5e-27 94.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 TFIIS_C PF01096.13 EPX74720.1 - 5.9e-20 70.6 15.1 3.1e-19 68.3 2.8 3.0 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EPX74720.1 - 5.2e-15 54.8 0.4 5.2e-15 54.8 0.3 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EPX74720.1 - 3.7e-05 23.4 6.9 0.012 15.4 0.4 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain DZR PF12773.2 EPX74720.1 - 0.011 15.5 0.4 0.011 15.5 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-C4_Topoisom PF01396.14 EPX74720.1 - 0.03 13.8 2.9 0.2 11.1 0.0 3.1 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Baculo_LEF5_C PF11792.3 EPX74720.1 - 0.052 12.9 0.3 0.052 12.9 0.2 2.3 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain DNA_ligase_ZBD PF03119.11 EPX74720.1 - 0.12 12.0 0.1 0.12 12.0 0.0 2.9 4 0 0 4 4 3 0 NAD-dependent DNA ligase C4 zinc finger domain C1_1 PF00130.17 EPX74720.1 - 0.17 11.6 7.4 0.19 11.4 0.4 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Elf1 PF05129.8 EPX74720.1 - 0.17 11.5 4.6 0.27 10.9 0.1 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like C1_4 PF07975.7 EPX74720.1 - 0.18 11.8 9.6 2.9 7.9 0.2 2.8 2 1 0 2 2 2 0 TFIIH C1-like domain zinc_ribbon_2 PF13240.1 EPX74720.1 - 0.23 10.9 0.3 0.23 10.9 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EPX74720.1 - 0.4 10.0 5.5 6.1 6.2 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 EPX74720.1 - 0.47 10.1 5.6 1.5 8.5 0.2 2.7 3 0 0 3 3 3 0 Putative transposase DNA-binding domain C1_3 PF07649.7 EPX74720.1 - 0.54 10.3 0.2 0.54 10.3 0.1 3.0 3 0 0 3 3 3 0 C1-like domain zf-TFIIB PF13453.1 EPX74720.1 - 0.66 9.2 3.0 2.1 7.6 0.7 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger PhnA_Zn_Ribbon PF08274.7 EPX74720.1 - 0.67 9.7 4.2 18 5.2 0.1 3.2 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Nudix_N_2 PF14803.1 EPX74720.1 - 1 9.1 6.9 0.38 10.4 1.3 2.4 2 1 0 2 2 2 0 Nudix N-terminal zf-Mss51 PF13824.1 EPX74720.1 - 1.2 9.0 4.4 0.7 9.7 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 PHD PF00628.24 EPX74720.1 - 1.8 8.3 8.5 7.3 6.3 1.8 2.6 2 1 0 2 2 2 0 PHD-finger NOB1_Zn_bind PF08772.6 EPX74720.1 - 2.7 7.8 5.8 1.6 8.6 1.6 2.3 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like IBR PF01485.16 EPX74720.1 - 5.4 6.9 11.7 4.9 7.0 0.5 2.6 2 1 0 2 2 2 0 IBR domain FSH1 PF03959.8 EPX74721.1 - 5e-48 163.3 0.0 1e-47 162.3 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EPX74721.1 - 2.4e-05 24.1 0.0 6.1e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPX74721.1 - 3.9e-05 23.1 0.0 0.024 14.0 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.13 EPX74721.1 - 0.03 13.5 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EPX74721.1 - 0.16 11.7 0.0 2.1 8.1 0.0 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family PMT PF02366.13 EPX74722.1 - 1.1e-62 211.5 17.3 1.1e-62 211.5 12.0 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EPX74722.1 - 2.8e-39 134.6 0.1 4.6e-39 133.9 0.1 1.4 1 0 0 1 1 1 1 MIR domain Hydrolase_like PF13242.1 EPX74723.1 - 3.9e-22 77.7 0.1 2.4e-21 75.2 0.0 2.3 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EPX74723.1 - 1.5e-18 66.5 0.0 3.6e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase CDP-OH_P_transf PF01066.16 EPX74723.1 - 3.6e-18 65.7 5.2 6.5e-18 64.8 3.6 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase HAD_2 PF13419.1 EPX74723.1 - 2.6e-05 24.5 0.1 0.0089 16.2 0.0 3.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPX74723.1 - 0.017 15.5 0.0 0.28 11.5 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PRP21_like_P PF12230.3 EPX74724.1 - 2.4e-59 200.6 3.2 2.4e-59 200.6 2.2 1.6 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EPX74724.1 - 2.6e-35 119.8 2.4 3.6e-19 68.1 0.2 2.3 2 0 0 2 2 2 2 Surp module CDP-OH_P_transf PF01066.16 EPX74725.1 - 6e-17 61.7 1.7 6e-17 61.7 1.2 2.3 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Dak1 PF02733.12 EPX74726.1 - 2.7e-135 450.1 3.4 3.8e-135 449.6 2.3 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EPX74726.1 - 6.5e-47 159.4 0.6 1.1e-46 158.6 0.4 1.4 1 0 0 1 1 1 1 DAK2 domain PIG-P PF08510.7 EPX74727.1 - 9.5e-30 102.8 6.3 2.6e-29 101.3 4.3 1.7 1 1 0 1 1 1 1 PIG-P DUF3671 PF12420.3 EPX74727.1 - 0.14 12.1 0.2 0.33 10.9 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF485 PF04341.7 EPX74727.1 - 0.21 11.3 0.3 0.21 11.3 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF485 DPM2 PF07297.7 EPX74727.1 - 2.3 8.5 6.5 3.6 7.9 4.5 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) BSD PF03909.12 EPX74729.1 - 2.1e-15 56.1 2.1 7.8e-15 54.3 1.4 2.0 1 0 0 1 1 1 1 BSD domain HSP70 PF00012.15 EPX74730.1 - 5.5e-265 879.9 9.5 6.3e-265 879.7 6.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPX74730.1 - 1.7e-21 76.1 0.3 4.9e-20 71.3 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EPX74730.1 - 0.0036 16.4 4.1 0.055 12.5 0.2 3.0 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EPX74730.1 - 0.11 12.0 0.0 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EPX74730.1 - 0.41 10.5 6.8 0.59 9.9 0.2 3.4 2 1 0 2 2 2 0 Cell division protein FtsA ATP-grasp_2 PF08442.5 EPX74731.1 - 2e-10 40.3 0.0 3.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain adh_short_C2 PF13561.1 EPX74732.1 - 1.7e-28 100.0 0.1 2.1e-28 99.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPX74732.1 - 8.4e-27 94.1 0.6 1.1e-26 93.7 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPX74732.1 - 2e-13 50.4 0.4 2.7e-13 49.9 0.3 1.1 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EPX74732.1 - 0.0032 16.4 0.3 0.047 12.5 0.0 2.1 1 1 1 2 2 2 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EPX74732.1 - 0.0033 17.1 0.0 0.0074 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EPX74732.1 - 0.034 13.5 0.2 0.08 12.3 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ras_bdg_2 PF14847.1 EPX74732.1 - 0.048 13.5 0.1 0.23 11.4 0.1 2.1 1 1 0 1 1 1 0 Ras-binding domain of Byr2 ATP-synt_ab PF00006.20 EPX74732.1 - 0.064 12.7 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TIM-br_sig_trns PF09370.5 EPX74732.1 - 0.069 12.2 0.3 0.15 11.0 0.1 1.8 1 1 1 2 2 2 0 TIM-barrel signal transduction protein Spore_IV_A PF09547.5 EPX74732.1 - 0.078 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) HAD_2 PF13419.1 EPX74733.1 - 7.2e-18 65.4 0.0 9.3e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPX74733.1 - 5.1e-12 46.6 0.0 4.7e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPX74733.1 - 2.6e-05 23.8 0.0 5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EPX74733.1 - 0.0019 18.0 0.0 0.59 10.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase NT5C PF06941.7 EPX74733.1 - 0.031 13.7 0.1 0.076 12.5 0.0 1.6 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) NIF PF03031.13 EPX74733.1 - 0.12 12.0 0.0 3 7.5 0.0 2.2 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Ras PF00071.17 EPX74734.1 - 7.8e-60 200.9 0.5 9.9e-60 200.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX74734.1 - 1.6e-20 73.7 0.0 3e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPX74734.1 - 1.9e-16 59.8 0.4 2.4e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPX74734.1 - 2.2e-07 30.4 0.1 9.8e-07 28.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPX74734.1 - 7.8e-07 28.4 0.9 9.6e-07 28.1 0.6 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EPX74734.1 - 2.5e-06 26.8 0.1 3.7e-06 26.2 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPX74734.1 - 1.1e-05 25.3 0.0 2.4e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPX74734.1 - 0.01 15.6 0.5 1.9 8.2 0.0 3.1 2 1 1 3 3 3 0 Dynamin family AAA_22 PF13401.1 EPX74734.1 - 0.012 15.7 0.1 0.31 11.1 0.0 2.5 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EPX74734.1 - 0.02 14.6 0.1 0.056 13.1 0.0 1.6 1 1 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 EPX74734.1 - 0.056 12.9 1.3 0.33 10.4 0.5 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EPX74734.1 - 0.13 12.1 0.4 0.25 11.2 0.3 1.5 1 1 0 1 1 1 0 AAA domain PQ-loop PF04193.9 EPX74735.1 - 4.4e-12 45.3 18.5 1.3e-09 37.4 0.6 3.6 3 0 0 3 3 3 2 PQ loop repeat MadM PF03818.8 EPX74735.1 - 0.02 14.4 1.5 0.098 12.2 1.0 2.2 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit DUF4231 PF14015.1 EPX74735.1 - 2.5 8.1 5.6 19 5.3 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2681 PF10883.3 EPX74735.1 - 9.1 6.5 6.2 0.68 10.1 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ThiF PF00899.16 EPX74736.1 - 1.6e-16 60.3 0.0 2.7e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family NIR_SIR PF01077.17 EPX74737.1 - 2.4e-46 156.9 0.1 2.2e-43 147.3 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EPX74737.1 - 1.2e-30 104.8 0.0 3.5e-14 52.1 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EPX74737.1 - 4.3e-30 104.6 0.0 1.5e-29 102.8 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin Flavodoxin_5 PF12724.2 EPX74737.1 - 0.03 14.3 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain OB_NTP_bind PF07717.11 EPX74738.1 - 1.2e-27 95.9 0.0 2.8e-27 94.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPX74738.1 - 1.7e-27 95.4 0.1 4.4e-27 94.0 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) S1 PF00575.18 EPX74738.1 - 8.1e-16 57.8 0.3 1.7e-15 56.8 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.26 EPX74738.1 - 9e-11 41.4 0.0 2.4e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPX74738.1 - 6.1e-08 32.3 0.2 1.2e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPX74738.1 - 3.6e-06 27.1 0.1 1.2e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EPX74738.1 - 0.0013 18.3 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPX74738.1 - 0.0016 18.7 8.1 0.02 15.2 0.2 3.7 3 1 0 3 3 3 1 ABC transporter SRP54 PF00448.17 EPX74738.1 - 0.005 16.2 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 EPX74738.1 - 0.0067 15.3 0.0 0.021 13.7 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EPX74738.1 - 0.0074 16.0 0.1 0.092 12.4 0.1 2.2 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_19 PF13245.1 EPX74738.1 - 0.0098 15.6 0.1 0.028 14.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EPX74738.1 - 0.011 15.6 0.1 0.17 11.7 0.1 2.6 2 1 0 2 2 1 0 AAA domain CTP_synth_N PF06418.9 EPX74739.1 - 6.7e-119 396.0 0.5 8.9e-119 395.6 0.3 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EPX74739.1 - 7.7e-55 185.3 0.0 1.2e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPX74739.1 - 1.8e-06 27.5 0.0 4.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EPX74739.1 - 0.024 14.0 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RCC1 PF00415.13 EPX74740.1 - 3.1e-27 94.5 7.8 5.3e-11 42.5 0.0 7.0 6 3 1 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPX74740.1 - 1.6e-15 56.2 20.3 1.7e-07 30.6 0.1 7.0 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Reg_prop PF07494.6 EPX74740.1 - 1.4 9.2 4.6 28 5.1 0.1 4.0 3 0 0 3 3 3 0 Two component regulator propeller UQ_con PF00179.21 EPX74741.1 - 2.6e-27 94.9 0.5 3.5e-27 94.5 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPX74741.1 - 0.057 13.3 0.3 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 RWD domain RRM_6 PF14259.1 EPX74742.1 - 3.5e-08 33.2 0.0 5.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX74742.1 - 3.2e-07 29.8 0.1 5.2e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74742.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.14 EPX74743.1 - 1.4e-09 38.0 2.5 1.4e-09 38.0 1.8 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPX74743.1 - 4.4e-06 26.9 1.3 4.4e-06 26.9 0.9 2.9 3 0 0 3 3 3 1 HMG-box domain SMC_N PF02463.14 EPX74744.1 - 4.2e-55 186.3 53.2 2.4e-53 180.6 36.9 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPX74744.1 - 8.9e-32 109.5 0.0 3e-31 107.8 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EPX74744.1 - 3.7e-11 43.5 19.8 2.2e-06 27.8 0.0 4.5 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EPX74744.1 - 4.4e-07 30.4 54.7 4.4e-07 30.4 37.9 6.8 2 2 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EPX74744.1 - 0.001 18.5 0.0 0.0027 17.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain TMF_TATA_bd PF12325.3 EPX74744.1 - 0.0045 16.7 4.0 0.0045 16.7 2.8 8.4 5 2 2 8 8 8 1 TATA element modulatory factor 1 TATA binding FtsK_SpoIIIE PF01580.13 EPX74744.1 - 0.35 10.2 5.9 0.37 10.2 0.0 3.6 3 1 0 3 3 3 0 FtsK/SpoIIIE family RIO1 PF01163.17 EPX74745.1 - 2e-74 249.0 0.2 2e-74 249.0 0.2 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EPX74745.1 - 0.0044 16.7 0.1 1.3 8.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Cut8_N PF14482.1 EPX74745.1 - 0.06 13.3 3.9 5.5 7.0 0.0 3.6 4 1 0 4 4 4 0 Cut8 proteasome-binding domain APG17 PF04108.7 EPX74746.1 - 1.1e-75 254.9 15.1 2.1e-75 254.0 10.4 1.4 1 1 0 1 1 1 1 Autophagy protein Apg17 TLE_N PF03920.10 EPX74746.1 - 0.0033 17.2 2.9 0.0033 17.2 2.0 1.9 2 1 0 2 2 2 1 Groucho/TLE N-terminal Q-rich domain Med2 PF11214.3 EPX74746.1 - 0.057 13.4 4.4 0.15 12.0 0.3 3.0 3 0 0 3 3 3 0 Mediator complex subunit 2 DUF3683 PF12447.3 EPX74746.1 - 0.57 10.0 3.4 0.79 9.5 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3683) Syntaxin-6_N PF09177.6 EPX74746.1 - 0.99 9.8 10.2 0.53 10.7 0.9 3.5 3 1 1 4 4 4 0 Syntaxin 6, N-terminal ICMT PF04140.9 EPX74747.1 - 3.9e-28 97.4 0.6 7.5e-28 96.5 0.4 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EPX74747.1 - 9.1e-13 48.2 1.4 9.1e-13 48.2 1.0 2.3 2 1 0 3 3 3 1 Phospholipid methyltransferase NnrU PF07298.6 EPX74747.1 - 4.9e-06 26.0 0.7 7.7e-06 25.4 0.5 1.4 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.7 EPX74747.1 - 0.007 15.6 0.9 0.0094 15.2 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Sterol-sensing PF12349.3 EPX74747.1 - 0.026 14.0 0.1 0.026 14.0 0.1 1.8 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation Aminotran_1_2 PF00155.16 EPX74748.1 - 1.1e-73 248.3 0.0 1.2e-73 248.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ABC1 PF03109.11 EPX74749.1 - 8.7e-30 103.1 0.3 1.7e-29 102.1 0.2 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EPX74749.1 - 0.0053 16.5 0.0 0.51 10.0 0.1 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 EPX74749.1 - 0.081 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) UPF0300 PF08594.5 EPX74750.1 - 2.4e-67 226.0 0.2 3.4e-67 225.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) Endosulfine PF04667.12 EPX74751.1 - 1.6e-20 72.8 0.0 2.3e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region PP2C PF00481.16 EPX74752.1 - 1.8e-41 142.2 0.0 2.8e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EPX74752.1 - 5.2e-05 22.7 0.0 0.00011 21.6 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Metal_resist PF13801.1 EPX74752.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Heavy-metal resistance Glyco_tran_28_C PF04101.11 EPX74753.1 - 1.3e-31 109.5 0.0 1.6e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EPX74753.1 - 0.002 17.3 0.0 0.002 17.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 DUF3326 PF11805.3 EPX74753.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Aminotran_1_2 PF00155.16 EPX74754.1 - 6.4e-22 77.9 0.0 8e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EPX74754.1 - 3.6e-06 25.8 0.0 5.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EPX74754.1 - 0.00036 19.6 0.0 0.0013 17.8 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Imm23 PF15593.1 EPX74754.1 - 0.13 12.5 0.2 0.13 12.5 0.2 1.6 2 0 0 2 2 2 0 Immunity protein 23 ACC_central PF08326.7 EPX74755.1 - 1.2e-256 853.3 0.0 1.5e-256 853.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EPX74755.1 - 2.9e-175 583.3 0.0 3.8e-175 582.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EPX74755.1 - 7.7e-52 175.6 0.1 1.6e-51 174.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EPX74755.1 - 9e-24 83.7 0.1 2e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EPX74755.1 - 5.6e-20 71.3 0.0 4.4e-19 68.4 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EPX74755.1 - 9.1e-15 54.0 0.2 2e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EPX74755.1 - 5e-11 42.6 0.0 1.2e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EPX74755.1 - 8.3e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EPX74755.1 - 0.032 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_3 PF02655.9 EPX74755.1 - 0.04 13.7 0.1 0.23 11.3 0.0 2.3 3 0 0 3 3 3 0 ATP-grasp domain DUF788 PF05620.6 EPX74756.1 - 1.2e-46 158.7 1.2 1.3e-46 158.5 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) G_glu_transpept PF01019.16 EPX74757.1 - 3.4e-164 547.1 0.0 3.9e-164 546.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Acetyltransf_7 PF13508.1 EPX74758.1 - 3.4e-06 27.1 0.0 7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPX74758.1 - 1e-05 25.3 0.1 5.2e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPX74758.1 - 0.00052 20.0 0.0 0.0011 18.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPX74758.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3295 PF11702.3 EPX74759.1 - 2.2e-33 116.0 40.3 5.7e-33 114.6 27.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EPX74759.1 - 2.9e-12 45.9 4.9 7.3e-12 44.6 3.4 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cpn60_TCP1 PF00118.19 EPX74760.1 - 1.2e-148 495.7 3.8 1.4e-148 495.5 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PCI PF01399.22 EPX74761.1 - 1.5e-19 70.2 2.1 3.9e-19 68.9 0.0 2.7 2 1 1 3 3 3 1 PCI domain FlbT PF07378.6 EPX74761.1 - 0.049 13.4 0.6 0.18 11.6 0.1 2.3 2 0 0 2 2 2 0 Flagellar protein FlbT CtaG_Cox11 PF04442.9 EPX74762.1 - 1.4e-55 187.2 0.0 2.4e-55 186.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Rsm22 PF09243.5 EPX74762.1 - 1.7e-41 142.1 0.0 2.6e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 EPX74762.1 - 0.0081 16.7 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX74762.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SIP1 PF04938.7 EPX74763.1 - 2.4e-06 27.0 2.4 7.6e-05 22.1 1.7 2.1 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Pex2_Pex12 PF04757.9 EPX74764.1 - 9.4e-19 67.7 9.9 2.4e-18 66.3 6.9 1.7 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EPX74764.1 - 1.2e-06 28.2 4.4 3e-06 26.9 3.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EPX74764.1 - 3.4e-06 26.9 3.0 8.3e-06 25.7 2.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX74764.1 - 7e-06 25.6 1.4 1.5e-05 24.5 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPX74764.1 - 0.00035 20.3 2.1 0.00066 19.4 1.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPX74764.1 - 0.00076 19.1 0.8 0.0014 18.2 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EPX74764.1 - 0.021 14.6 0.1 0.051 13.4 0.1 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.2 EPX74764.1 - 0.11 12.6 1.4 0.41 10.7 0.9 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger PCI PF01399.22 EPX74765.1 - 4.7e-18 65.4 2.4 4.7e-18 65.4 1.7 2.8 2 1 1 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EPX74765.1 - 3.2e-08 33.4 3.5 5.1e-08 32.7 0.3 2.4 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 EPX74765.1 - 0.013 15.2 0.3 32 4.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPX74765.1 - 0.066 13.1 0.0 3.9 7.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPX74765.1 - 0.17 11.7 1.4 1.8 8.5 0.7 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Rapamycin_bind PF08771.6 EPX74765.1 - 0.33 11.0 8.7 1.6 8.8 0.3 3.7 2 1 1 3 3 3 0 Rapamycin binding domain YL1 PF05764.8 EPX74765.1 - 2.1 7.8 6.8 3.8 7.0 4.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Ribosomal_L37e PF01907.14 EPX74766.1 - 1.1e-25 89.2 14.6 1.7e-25 88.5 10.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EPX74766.1 - 0.00057 19.6 2.9 0.00083 19.1 2.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-C3HC4_2 PF13923.1 EPX74766.1 - 0.12 12.4 3.8 0.18 11.8 2.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX74766.1 - 0.14 11.9 3.5 0.21 11.3 2.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain HypA PF01155.14 EPX74766.1 - 0.28 10.9 1.3 0.38 10.4 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EPX74766.1 - 0.55 9.5 4.0 2.1 7.6 2.7 1.9 1 1 1 2 2 2 0 zinc-ribbon domain GATA PF00320.22 EPX74766.1 - 0.55 9.6 6.7 0.51 9.7 0.9 2.3 1 1 1 2 2 2 0 GATA zinc finger zf-C3HC4 PF00097.20 EPX74766.1 - 0.91 9.2 5.4 1.4 8.6 3.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_RNApol_7kD PF03604.8 EPX74766.1 - 6.3 6.3 6.9 4.6 6.8 1.1 2.2 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Vac_Fusion PF02346.11 EPX74767.1 - 0.0043 16.4 0.6 0.0043 16.4 0.4 2.6 2 1 1 3 3 3 1 Chordopoxvirus fusion protein COG5 PF10392.4 EPX74767.1 - 0.008 16.1 2.8 0.008 16.1 2.0 2.6 1 1 2 3 3 3 1 Golgi transport complex subunit 5 Tropomyosin_1 PF12718.2 EPX74767.1 - 0.011 15.5 27.0 0.013 15.3 15.5 2.6 2 1 0 2 2 2 0 Tropomyosin like Bap31 PF05529.7 EPX74767.1 - 0.014 14.8 1.9 0.014 14.8 1.3 2.8 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Synaptobrevin PF00957.16 EPX74767.1 - 0.088 12.4 6.3 0.17 11.5 1.2 2.3 2 0 0 2 2 2 0 Synaptobrevin DUF3166 PF11365.3 EPX74767.1 - 0.78 10.2 10.7 12 6.4 1.7 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3166) ADIP PF11559.3 EPX74767.1 - 1.1 9.0 20.5 2.2 8.1 3.8 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4201 PF13870.1 EPX74767.1 - 1.5 8.2 22.5 0.19 11.1 5.5 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) HALZ PF02183.13 EPX74767.1 - 2.5 7.8 22.3 7.2 6.4 0.4 4.7 3 2 1 4 4 4 0 Homeobox associated leucine zipper GrpE PF01025.14 EPX74767.1 - 3.7 7.0 16.9 0.38 10.2 0.9 2.7 1 1 1 2 2 2 0 GrpE CENP-Q PF13094.1 EPX74767.1 - 5.5 7.0 24.3 0.03 14.3 3.7 2.6 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4404 PF14357.1 EPX74767.1 - 7.8 7.0 11.0 5.4 7.5 0.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Bacillus_HBL PF05791.6 EPX74767.1 - 8.1 5.7 16.7 1.1 8.5 0.9 3.5 2 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) tRNA_int_endo PF01974.12 EPX74768.1 - 1.8e-18 66.0 0.1 3.4e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EPX74768.1 - 9.2e-06 25.1 0.0 0.062 12.8 0.0 2.6 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain DUF1043 PF06295.7 EPX74768.1 - 0.16 11.5 0.1 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) EOS1 PF12326.3 EPX74769.1 - 9.5e-46 155.1 9.9 9.5e-46 155.1 6.9 1.6 2 0 0 2 2 2 1 N-glycosylation protein FtsJ PF01728.14 EPX74770.1 - 3.7e-24 85.6 0.0 6.7e-24 84.8 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 EPX74770.1 - 0.042 13.3 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubiq_cyt_C_chap PF03981.7 EPX74771.1 - 0.093 12.5 1.7 0.15 11.9 1.2 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Neur_chan_memb PF02932.11 EPX74771.1 - 0.96 9.2 3.3 1.2 9.0 2.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.14 EPX74771.1 - 2.5 5.8 9.1 2.6 5.7 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EPX74771.1 - 6.6 7.1 15.1 10 6.5 5.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF972) OST3_OST6 PF04756.8 EPX74772.1 - 3e-18 65.9 3.4 7.6e-18 64.5 2.3 1.6 2 0 0 2 2 2 1 OST3 / OST6 family Thioredoxin PF00085.15 EPX74772.1 - 8.1e-08 31.8 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EPX74772.1 - 0.098 12.8 0.2 0.3 11.2 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Lig_chan PF00060.21 EPX74772.1 - 1.2 8.8 4.9 2.5 7.8 3.4 1.6 1 0 0 1 1 1 0 Ligand-gated ion channel Mito_carr PF00153.22 EPX74773.1 - 7.1e-68 224.3 0.5 2.1e-22 78.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EPX74773.1 - 0.043 13.6 1.0 9.1 6.1 0.1 2.4 2 0 0 2 2 2 0 UcrQ family CM_1 PF07736.6 EPX74773.1 - 0.17 12.0 0.0 24 5.0 0.0 2.3 2 0 0 2 2 2 0 Chorismate mutase type I Ribosomal_L18e PF00828.14 EPX74774.1 - 5.9e-28 97.8 0.3 5.9e-28 97.8 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 6PF2K PF01591.13 EPX74775.1 - 5.4e-76 254.5 0.1 8.1e-76 253.9 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EPX74775.1 - 2.6e-22 79.6 0.1 1.5e-21 77.1 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EPX74775.1 - 1.6e-06 28.0 0.0 1.1e-05 25.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain DUF2313 PF10076.4 EPX74775.1 - 0.0012 18.3 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2313) AAA_17 PF13207.1 EPX74775.1 - 0.0057 17.4 0.0 0.014 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EPX74775.1 - 0.029 13.5 0.0 0.084 12.0 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Uso1_p115_head PF04869.9 EPX74775.1 - 0.056 12.1 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region Zeta_toxin PF06414.7 EPX74775.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin HIG_1_N PF04588.8 EPX74776.1 - 2.6e-05 23.8 0.2 5.5e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region SR-25 PF10500.4 EPX74776.1 - 0.11 11.9 5.4 0.14 11.5 3.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RhoGAP PF00620.22 EPX74777.1 - 1.1e-21 77.0 0.4 2.5e-21 75.8 0.3 1.6 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 EPX74777.1 - 4.1e-19 68.9 2.9 8.1e-19 67.9 2.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EPX74777.1 - 6.7e-05 22.4 0.5 0.00017 21.1 0.3 1.8 1 1 0 1 1 1 1 CRAL/TRIO domain ATXN-1_C PF12547.3 EPX74778.1 - 0.053 13.4 1.0 0.053 13.4 0.7 3.9 3 2 0 3 3 3 0 Capicua transcriptional repressor modulator TYA PF01021.14 EPX74778.1 - 0.5 10.5 4.4 0.34 11.1 0.4 2.3 1 1 1 2 2 2 0 TYA transposon protein SAM_1 PF00536.25 EPX74779.1 - 1.3e-14 54.0 0.0 2.9e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EPX74779.1 - 8e-13 48.0 0.1 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EPX74779.1 - 5e-10 39.7 0.0 8.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FliD_N PF02465.13 EPX74779.1 - 0.0021 18.3 0.9 0.0047 17.2 0.3 2.0 1 1 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus bZIP_1 PF00170.16 EPX74779.1 - 0.017 15.0 0.9 0.017 15.0 0.6 2.2 1 1 1 2 2 2 0 bZIP transcription factor DDHD PF02862.12 EPX74779.1 - 0.028 14.2 0.5 0.028 14.2 0.3 1.5 2 0 0 2 2 2 0 DDHD domain bZIP_2 PF07716.10 EPX74779.1 - 0.038 13.8 0.8 0.038 13.8 0.5 1.8 2 0 0 2 2 2 0 Basic region leucine zipper V_ATPase_I PF01496.14 EPX74779.1 - 0.55 8.0 3.0 0.63 7.8 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EPX74779.1 - 1.4 8.4 6.5 0.76 9.3 0.5 2.2 1 1 1 2 2 2 0 Septum formation initiator Sec3-PIP2_bind PF15277.1 EPX74780.1 - 0.091 12.6 0.6 3.3 7.6 0.0 2.9 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Ras PF00071.17 EPX74781.1 - 2.3e-34 118.1 0.4 2.7e-34 117.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX74781.1 - 1.1e-22 80.8 0.2 3.7e-22 79.0 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPX74781.1 - 1.7e-08 33.8 0.2 1.9e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPX74781.1 - 2.1e-08 33.6 0.4 2.5e-08 33.3 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPX74781.1 - 1.2e-05 24.8 0.3 7.5e-05 22.2 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPX74781.1 - 0.001 19.0 0.0 0.0014 18.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DLIC PF05783.6 EPX74781.1 - 0.0018 17.0 1.1 0.24 10.0 0.0 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 EPX74781.1 - 0.0036 16.0 3.9 0.018 13.7 1.2 2.6 1 1 1 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.4 EPX74781.1 - 0.0071 15.8 0.6 0.034 13.6 0.4 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EPX74781.1 - 0.058 12.6 0.1 0.074 12.2 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TIP120 PF08623.5 EPX74782.1 - 5.3e-40 136.7 8.5 2.8e-39 134.3 0.4 4.5 5 1 0 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EPX74782.1 - 1.9e-15 56.8 4.3 1.6e-05 25.0 0.1 7.1 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 EPX74782.1 - 2.2e-08 33.4 7.8 0.09 12.9 0.0 7.8 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 EPX74782.1 - 3.4e-06 27.3 0.5 15 6.2 0.0 7.6 9 1 1 10 10 10 1 HEAT-like repeat Arm PF00514.18 EPX74782.1 - 0.00036 20.2 4.1 2 8.3 0.0 4.8 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EPX74782.1 - 0.012 15.5 11.6 1.2 9.1 0.1 5.7 6 0 0 6 6 6 0 Protein of unknown function (DUF2435) AAA PF00004.24 EPX74783.1 - 9.9e-99 326.7 0.0 6.6e-49 165.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EPX74783.1 - 8.5e-20 70.5 1.0 2.6e-19 68.9 0.7 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EPX74783.1 - 1.6e-14 54.2 0.0 9.1e-08 32.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EPX74783.1 - 1.7e-13 50.2 0.0 7.8e-06 25.1 0.0 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EPX74783.1 - 3.3e-12 46.4 0.0 1.3e-05 25.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 EPX74783.1 - 1.3e-11 44.4 2.0 8.5e-06 25.5 0.0 4.8 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPX74783.1 - 1.4e-11 44.6 0.5 0.0023 18.0 0.1 4.8 3 2 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EPX74783.1 - 2.9e-11 44.2 0.0 0.00056 20.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPX74783.1 - 7.9e-10 39.0 0.0 0.0026 17.7 0.0 4.0 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 EPX74783.1 - 1.2e-09 37.3 0.1 0.00088 18.0 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EPX74783.1 - 1.2e-08 34.6 0.0 0.0011 18.4 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein CDC48_2 PF02933.12 EPX74783.1 - 5.6e-08 32.3 0.0 1.5e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EPX74783.1 - 1.2e-07 31.7 0.0 0.0035 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EPX74783.1 - 1.6e-07 30.6 0.4 0.019 14.1 0.0 2.8 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EPX74783.1 - 1.7e-07 30.5 0.0 0.0054 15.8 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 EPX74783.1 - 5.1e-07 29.3 2.0 0.015 15.0 0.1 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 EPX74783.1 - 5.9e-07 29.0 6.0 0.091 12.1 0.0 4.5 3 2 1 5 5 4 2 AAA domain AAA_18 PF13238.1 EPX74783.1 - 6.5e-07 29.7 0.0 0.017 15.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 EPX74783.1 - 7.5e-07 29.2 0.0 0.036 14.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 EPX74783.1 - 2.1e-06 27.0 1.1 0.44 9.6 0.0 3.8 2 1 1 3 3 3 2 KaiC ResIII PF04851.10 EPX74783.1 - 3.8e-06 26.8 0.1 0.0033 17.2 0.0 2.6 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EPX74783.1 - 6.5e-06 25.2 0.1 0.03 13.1 0.0 2.5 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 EPX74783.1 - 7.6e-06 25.9 0.2 0.15 12.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 EPX74783.1 - 1.2e-05 25.5 0.0 0.089 13.0 0.0 3.9 4 1 0 4 4 2 1 ABC transporter Sigma54_activat PF00158.21 EPX74783.1 - 1.7e-05 24.3 0.0 0.38 10.2 0.0 3.5 2 2 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 EPX74783.1 - 2.8e-05 23.1 0.0 0.024 13.5 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 EPX74783.1 - 3.5e-05 23.8 0.0 0.32 11.0 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EPX74783.1 - 3.7e-05 23.5 0.3 5.2 6.7 0.0 4.4 3 2 2 5 5 4 0 Archaeal ATPase PhoH PF02562.11 EPX74783.1 - 5e-05 22.6 0.2 0.18 11.0 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 EPX74783.1 - 5.3e-05 22.8 0.0 0.27 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 EPX74783.1 - 0.0003 20.4 0.0 0.62 9.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EPX74783.1 - 0.00034 20.2 0.0 0.88 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EPX74783.1 - 0.00046 19.2 0.0 0.68 8.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EPX74783.1 - 0.00051 19.7 0.1 1.5 8.4 0.0 3.4 3 0 0 3 3 3 1 NACHT domain Bac_DnaA PF00308.13 EPX74783.1 - 0.00096 18.8 0.0 1.4 8.5 0.0 2.8 3 0 0 3 3 2 1 Bacterial dnaA protein AAA_30 PF13604.1 EPX74783.1 - 0.00096 18.7 0.0 1.7 8.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 EPX74783.1 - 0.0018 18.0 0.5 1.3 8.7 0.0 4.1 4 0 0 4 4 4 1 NTPase T2SE PF00437.15 EPX74783.1 - 0.003 16.5 0.0 0.27 10.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EPX74783.1 - 0.0031 17.0 0.0 0.45 10.0 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EPX74783.1 - 0.0069 15.2 0.1 1.8 7.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_10 PF12846.2 EPX74783.1 - 0.0091 15.4 1.1 1.4 8.3 0.0 3.6 3 1 1 4 4 4 1 AAA-like domain IPT PF01745.11 EPX74783.1 - 0.012 14.8 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Molydop_binding PF01568.16 EPX74783.1 - 0.023 14.5 0.1 0.058 13.2 0.1 1.7 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain SKI PF01202.17 EPX74783.1 - 0.024 14.5 0.1 4 7.2 0.0 3.1 3 0 0 3 3 2 0 Shikimate kinase eIF-1a PF01176.14 EPX74783.1 - 0.025 13.9 0.6 0.59 9.5 0.1 2.9 2 1 1 3 3 3 0 Translation initiation factor 1A / IF-1 KAP_NTPase PF07693.9 EPX74783.1 - 0.025 13.5 0.4 0.98 8.3 0.0 2.9 2 2 2 4 4 4 0 KAP family P-loop domain UPF0079 PF02367.12 EPX74783.1 - 0.039 13.5 0.1 4 7.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Vps4_C PF09336.5 EPX74783.1 - 0.055 13.3 0.1 0.35 10.8 0.1 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain KTI12 PF08433.5 EPX74783.1 - 0.08 12.1 1.1 4.3 6.4 0.0 3.0 3 0 0 3 3 2 0 Chromatin associated protein KTI12 Zot PF05707.7 EPX74783.1 - 0.12 11.8 0.4 12 5.3 0.1 3.7 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) zf-C2H2 PF00096.21 EPX74784.1 - 1.8e-11 43.6 3.7 4.5e-06 26.6 0.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPX74784.1 - 3.6e-09 36.3 4.1 0.0001 22.3 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPX74784.1 - 9.9e-08 31.9 6.7 5.1e-05 23.3 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EPX74784.1 - 0.013 15.6 1.1 0.032 14.3 0.3 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPX74784.1 - 0.1 12.8 0.5 0.25 11.5 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EPX74784.1 - 5.1 7.1 6.0 5.1 7.1 0.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger SNARE PF05739.14 EPX74785.1 - 9.6e-15 54.0 3.8 9.6e-15 54.0 2.6 3.1 3 0 0 3 3 3 1 SNARE domain Use1 PF09753.4 EPX74785.1 - 0.0039 16.6 3.2 0.052 12.9 2.2 2.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 Tropomyosin PF00261.15 EPX74785.1 - 0.0056 15.8 7.6 0.079 12.0 0.2 2.1 2 0 0 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 EPX74785.1 - 0.0092 15.8 7.1 0.14 11.9 0.1 2.3 2 0 0 2 2 2 2 Tropomyosin like DegS PF05384.6 EPX74785.1 - 0.015 14.4 5.5 0.036 13.2 0.1 2.4 2 0 0 2 2 2 0 Sensor protein DegS DUF745 PF05335.8 EPX74785.1 - 0.02 14.4 4.1 1.5 8.2 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DivIVA PF05103.8 EPX74785.1 - 0.2 11.7 7.6 0.027 14.5 1.3 2.2 2 1 0 2 2 2 0 DivIVA protein MutS_IV PF05190.13 EPX74785.1 - 0.25 11.5 5.2 0.23 11.6 0.7 2.6 2 1 1 3 3 3 0 MutS family domain IV CDC37_N PF03234.9 EPX74785.1 - 0.3 11.3 10.2 4.1 7.6 7.1 2.1 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Ly49 PF08391.5 EPX74785.1 - 0.69 10.0 5.5 1.4 9.0 0.2 2.8 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region DUF1811 PF08838.5 EPX74785.1 - 0.81 9.6 3.5 0.62 10.0 0.2 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1811) DUF4164 PF13747.1 EPX74785.1 - 8.7 6.5 13.9 2.4 8.3 1.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.14 EPX74785.1 - 9.7 3.9 7.2 1.7 6.4 1.8 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family COPI_assoc PF08507.5 EPX74786.1 - 1.7e-31 108.7 3.5 1.8e-31 108.6 2.4 1.0 1 0 0 1 1 1 1 COPI associated protein DUF2371 PF10177.4 EPX74786.1 - 0.06 13.2 2.1 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Cg6151-P PF10233.4 EPX74786.1 - 1.2 9.1 7.7 4.2 7.3 5.4 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Anoctamin PF04547.7 EPX74786.1 - 5.9 5.4 6.0 2.1 6.8 2.5 1.5 1 1 1 2 2 2 0 Calcium-activated chloride channel TPK_catalytic PF04263.11 EPX74787.1 - 2.5e-34 117.5 0.1 3.9e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EPX74787.1 - 7e-16 57.7 0.1 1.4e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain NUDIX PF00293.23 EPX74787.1 - 2.6e-08 33.5 0.0 6.8e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain Rho_GDI PF02115.12 EPX74788.1 - 1.4e-58 197.5 0.1 1.6e-58 197.4 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor MAS20 PF02064.10 EPX74789.1 - 2.5e-20 72.6 2.2 1.3e-19 70.3 1.5 1.8 1 1 0 1 1 1 1 MAS20 protein import receptor TraI PF07057.6 EPX74789.1 - 0.11 12.5 0.1 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 DNA helicase TraI PriCT_1 PF08708.6 EPX74789.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) Vps51 PF08700.6 EPX74790.1 - 0.00083 19.1 0.4 0.00083 19.1 0.3 2.5 3 0 0 3 3 3 1 Vps51/Vps67 RdRP PF05183.7 EPX74791.1 - 1.3e-159 532.5 0.3 2.1e-159 531.9 0.1 1.4 2 0 0 2 2 2 1 RNA dependent RNA polymerase GATase_5 PF13507.1 EPX74792.1 - 1.3e-92 309.3 0.0 2e-92 308.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EPX74792.1 - 1.7e-45 154.7 0.1 3.6e-25 88.7 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EPX74792.1 - 4.9e-24 84.3 0.3 2.3e-23 82.2 0.0 2.4 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Tau95 PF09734.4 EPX74793.1 - 1.9e-61 208.1 0.3 2.6e-61 207.6 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit PilN PF05137.8 EPX74793.1 - 0.18 11.6 0.3 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) B56 PF01603.15 EPX74794.1 - 8.2e-144 479.1 13.4 1.1e-143 478.8 9.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2122 PF09895.4 EPX74794.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) polyprenyl_synt PF00348.12 EPX74795.1 - 1.7e-73 246.6 0.0 2.1e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase APC8 PF04049.8 EPX74796.1 - 1.2e-38 132.0 1.9 1.2e-38 132.0 1.3 2.7 3 0 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EPX74796.1 - 4.5e-32 108.3 16.5 1.6e-05 24.3 0.2 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 EPX74796.1 - 3.2e-28 97.1 16.5 1e-07 31.4 0.3 6.7 4 1 4 8 8 8 7 TPR repeat TPR_2 PF07719.12 EPX74796.1 - 1e-26 90.6 23.5 0.00016 21.3 0.2 8.9 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 EPX74796.1 - 2.8e-23 79.8 14.6 0.00052 19.5 0.0 9.1 7 1 2 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EPX74796.1 - 8.4e-23 80.4 10.5 0.00047 20.7 0.0 6.9 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EPX74796.1 - 1.2e-20 72.0 9.1 0.042 14.4 0.0 8.6 5 2 4 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 EPX74796.1 - 1.3e-17 63.5 16.2 0.0031 17.4 0.0 7.0 5 1 1 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EPX74796.1 - 1.9e-15 55.3 10.7 0.0058 16.3 0.0 7.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPX74796.1 - 1.4e-12 47.8 11.4 0.0012 19.1 0.0 6.9 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPX74796.1 - 3.1e-11 42.5 11.9 0.037 14.2 0.0 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPX74796.1 - 9e-10 38.3 17.3 1.4 9.5 0.1 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 EPX74796.1 - 2.5e-09 37.1 16.6 0.015 15.4 0.6 5.5 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EPX74796.1 - 1.6e-05 24.6 9.7 0.35 10.7 0.7 5.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EPX74796.1 - 0.00013 21.8 14.3 2.5 8.1 0.0 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPX74796.1 - 0.0005 19.2 8.3 0.58 9.1 0.0 4.3 3 2 2 5 5 5 2 Tetratricopeptide repeat DUF3856 PF12968.2 EPX74796.1 - 0.011 15.5 1.1 0.83 9.4 0.1 2.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) ChAPs PF09295.5 EPX74796.1 - 0.012 14.4 0.3 7.6 5.1 0.0 3.1 2 1 2 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.4 EPX74796.1 - 0.012 15.0 3.6 8.1 5.7 0.0 4.3 3 2 1 4 4 4 0 26S proteasome subunit RPN7 BTAD PF03704.12 EPX74796.1 - 0.25 11.6 6.9 0.33 11.2 1.1 3.4 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_11 PF13414.1 EPX74797.1 - 6.5e-33 112.2 1.9 5.5e-12 45.1 0.0 7.4 4 2 4 8 8 8 6 TPR repeat TPR_1 PF00515.23 EPX74797.1 - 2.6e-29 99.5 0.1 7.1e-07 28.5 0.1 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EPX74797.1 - 2e-28 96.0 4.3 0.00013 21.6 0.0 9.6 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 EPX74797.1 - 2.4e-27 94.6 4.8 2.7e-09 36.8 0.0 7.9 5 2 2 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EPX74797.1 - 1.6e-22 79.4 8.9 8.9e-17 61.0 1.4 5.1 4 2 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EPX74797.1 - 1.5e-20 71.3 0.4 0.00042 19.9 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPX74797.1 - 1.3e-16 58.9 7.6 0.00046 19.7 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPX74797.1 - 2.1e-15 55.8 0.5 0.0021 18.5 0.1 8.0 4 3 4 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPX74797.1 - 9.6e-11 41.8 3.6 0.04 14.2 0.1 6.4 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPX74797.1 - 3.2e-10 40.3 0.0 0.023 15.3 0.0 5.6 6 1 0 7 7 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPX74797.1 - 6.9e-07 28.9 0.0 16 5.9 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPX74797.1 - 3.4e-06 26.8 0.0 0.82 9.6 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPX74797.1 - 2.5e-05 23.4 0.5 0.081 11.9 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPX74797.1 - 0.00072 19.8 10.1 2.7 8.6 0.0 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF3856 PF12968.2 EPX74797.1 - 0.03 14.1 0.0 6.9 6.4 0.0 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) rRNA_proc-arch PF13234.1 EPX74798.1 - 1.2e-92 309.9 0.3 2e-92 309.1 0.2 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EPX74798.1 - 5.3e-65 218.0 1.9 5.5e-65 217.9 0.2 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EPX74798.1 - 1.1e-21 77.0 0.4 4.2e-21 75.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX74798.1 - 5.8e-07 29.2 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPX74798.1 - 0.011 15.9 0.0 0.074 13.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EPX74798.1 - 0.017 14.0 0.0 0.045 12.6 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Rbsn PF11464.3 EPX74798.1 - 0.17 11.4 4.5 4.8 6.8 0.2 2.6 2 0 0 2 2 2 0 Rabenosyn Rab binding domain Suf PF05843.9 EPX74799.1 - 1.7e-77 260.9 0.4 7.8e-73 245.6 0.0 4.0 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EPX74799.1 - 0.0014 19.1 0.3 6.8 7.6 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPX74799.1 - 0.054 13.3 0.1 4.9 7.2 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Nup35_RRM PF05172.8 EPX74800.1 - 3.4e-25 87.7 0.0 7.6e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EPX74800.1 - 8.1e-09 35.1 0.0 1.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 EPX74801.1 - 1e-58 198.5 0.0 2.1e-58 197.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74801.1 - 5.4e-37 127.2 0.1 1.1e-23 83.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPX74801.1 - 4e-05 22.7 0.0 8.7e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Mst1_SARAH PF11629.3 EPX74801.1 - 0.032 14.0 3.9 0.16 11.8 0.6 2.7 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 ZYG-11_interact PF05884.7 EPX74801.1 - 1.3 7.9 3.5 2.2 7.2 2.4 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 Cyclin PF08613.6 EPX74803.1 - 5.8e-23 81.9 1.7 1.3e-22 80.8 0.6 1.9 2 0 0 2 2 2 1 Cyclin Phosphoprotein PF00922.12 EPX74803.1 - 0.073 12.2 3.6 0.14 11.3 2.5 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Cyclin_N PF00134.18 EPX74803.1 - 0.077 12.5 0.1 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain Pkinase PF00069.20 EPX74804.1 - 5.6e-61 205.9 0.0 8.8e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74804.1 - 2.1e-33 115.4 0.0 3.3e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX74804.1 - 0.0018 17.3 0.0 0.0041 16.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPX74804.1 - 0.051 12.6 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGEF PF00621.15 EPX74805.1 - 1.7e-05 24.8 7.1 0.005 16.7 4.9 2.4 1 1 0 1 1 1 1 RhoGEF domain Sgf11 PF08209.6 EPX74806.1 - 2e-13 49.3 1.3 2e-13 49.3 0.9 2.1 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 EPX74806.1 - 0.0034 17.0 2.7 0.0087 15.6 0.1 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-CpG_bind_C PF12269.3 EPX74806.1 - 0.079 12.4 3.0 0.14 11.6 2.1 1.4 1 1 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Fer4_10 PF13237.1 EPX74806.1 - 0.17 11.7 5.5 0.28 11.0 3.8 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain WD40 PF00400.27 EPX74807.1 - 1.2e-59 196.2 26.8 4.2e-11 42.2 1.3 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EPX74807.1 - 1.3e-14 53.6 1.0 3e-14 52.4 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPX74807.1 - 2.5e-10 39.7 0.6 6.8e-10 38.3 0.4 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EPX74807.1 - 8.6e-05 20.8 9.3 0.18 9.9 0.1 4.5 2 1 2 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EPX74807.1 - 0.043 13.5 0.0 24 4.7 0.0 3.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PRANC PF09372.5 EPX74807.1 - 0.058 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 PRANC domain DUF218 PF02698.12 EPX74809.1 - 1.7e-05 24.3 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Abhydrolase_6 PF12697.2 EPX74810.1 - 1.5e-26 93.7 0.0 2e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPX74810.1 - 1.7e-18 66.7 0.0 5.6e-18 65.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPX74810.1 - 1.4e-17 64.0 0.0 4e-16 59.2 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EPX74810.1 - 1.2e-05 24.8 0.0 0.0058 16.1 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EPX74810.1 - 7e-05 22.5 0.0 0.00035 20.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EPX74810.1 - 8.7e-05 22.2 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EPX74810.1 - 0.00014 21.4 0.1 0.00049 19.7 0.0 2.1 2 1 0 2 2 2 1 Lipase (class 3) DUF2305 PF10230.4 EPX74810.1 - 0.00026 20.4 0.0 0.00058 19.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF3530 PF12048.3 EPX74810.1 - 0.00028 19.9 0.0 0.00049 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Thioesterase PF00975.15 EPX74810.1 - 0.00028 21.1 0.0 0.00063 20.0 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 EPX74810.1 - 0.00036 20.3 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EPX74810.1 - 0.0053 15.9 0.0 0.52 9.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EPX74810.1 - 0.0068 16.1 0.0 0.019 14.6 0.0 1.8 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.7 EPX74810.1 - 0.0075 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.2 EPX74810.1 - 0.0098 14.8 0.0 0.028 13.3 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme DUF915 PF06028.6 EPX74810.1 - 0.017 14.1 0.0 0.33 10.0 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2235 PF09994.4 EPX74810.1 - 0.041 13.2 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ser_hydrolase PF06821.8 EPX74810.1 - 0.041 13.4 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase Ndr PF03096.9 EPX74810.1 - 0.049 12.0 0.0 0.081 11.3 0.0 1.4 1 0 0 1 1 1 0 Ndr family FSH1 PF03959.8 EPX74810.1 - 0.075 12.4 0.1 0.96 8.8 0.0 2.4 2 1 0 2 2 2 0 Serine hydrolase (FSH1) La PF05383.12 EPX74811.1 - 5e-24 83.8 0.0 8.7e-24 83.1 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EPX74811.1 - 2.8e-08 33.2 0.4 5.4e-08 32.3 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74811.1 - 8.9e-06 25.6 0.1 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.7 EPX74811.1 - 0.037 13.6 0.1 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 HMG_box PF00505.14 EPX74812.1 - 3.7e-24 84.7 0.5 3.7e-24 84.7 0.3 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPX74812.1 - 1.4e-15 57.3 0.8 1.4e-15 57.3 0.5 1.5 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 EPX74812.1 - 0.072 12.8 2.7 0.18 11.5 1.8 1.7 1 1 0 1 1 1 0 HMG (high mobility group) box 5 CHCH PF06747.8 EPX74813.1 - 4.6e-06 26.4 7.1 8.8e-06 25.5 4.9 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EPX74813.1 - 1.8 8.7 7.9 0.16 12.0 2.0 1.9 2 0 0 2 2 2 0 GCK domain Spore_II_R PF09551.5 EPX74813.1 - 3.7 7.5 5.6 0.82 9.7 1.4 1.7 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) DHO_dh PF01180.16 EPX74814.1 - 3.4e-114 380.7 0.0 3.9e-114 380.5 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EPX74814.1 - 0.0021 17.3 1.2 0.078 12.2 0.0 2.5 2 1 1 3 3 3 1 PcrB family FMN_dh PF01070.13 EPX74814.1 - 0.0084 14.9 0.0 0.052 12.3 0.0 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EPX74814.1 - 0.024 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Dus PF01207.12 EPX74814.1 - 0.029 13.1 0.0 1.2 7.9 0.0 2.1 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) Response_reg PF00072.19 EPX74814.1 - 0.084 12.8 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Response regulator receiver domain His_biosynth PF00977.16 EPX74814.1 - 0.094 11.9 0.1 1.9 7.7 0.0 2.2 1 1 0 2 2 2 0 Histidine biosynthesis protein EF1_GNE PF00736.14 EPX74814.1 - 0.096 12.3 0.1 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 EF-1 guanine nucleotide exchange domain DNA_ligase_A_M PF01068.16 EPX74815.1 - 4e-65 218.9 0.3 4e-65 218.9 0.2 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPX74815.1 - 9.3e-51 172.1 0.1 1.9e-50 171.1 0.1 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPX74815.1 - 9.5e-27 93.2 0.0 3.1e-26 91.6 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 EPX74815.1 - 0.0005 19.8 0.1 0.012 15.2 0.1 2.4 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_OB_2 PF14743.1 EPX74815.1 - 0.014 15.0 0.1 6.8 6.4 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain DDHD PF02862.12 EPX74816.1 - 3.2e-49 167.7 1.5 1.7e-48 165.3 0.2 2.5 2 1 0 2 2 2 1 DDHD domain AMIN PF11741.3 EPX74816.1 - 0.091 12.7 0.1 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AMIN domain DUF676 PF05057.9 EPX74816.1 - 0.12 11.5 0.0 0.35 10.1 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Sugar_tr PF00083.19 EPX74817.1 - 1.2e-108 363.6 31.4 1.4e-108 363.4 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPX74817.1 - 3.8e-25 88.3 54.8 2.9e-24 85.4 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EPX74817.1 - 0.0057 14.8 13.0 0.061 11.4 2.0 2.5 2 1 0 2 2 2 2 Transmembrane secretion effector ETF_QO PF05187.8 EPX74818.1 - 2.1e-38 130.6 0.0 3.4e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase Thi4 PF01946.12 EPX74818.1 - 1.1e-07 31.2 0.0 0.00013 21.1 0.1 2.2 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EPX74818.1 - 2.7e-07 29.8 0.4 0.0041 16.0 0.8 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPX74818.1 - 6.7e-07 28.4 0.7 0.0053 15.6 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EPX74818.1 - 2.9e-05 24.0 0.1 0.0001 22.2 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPX74818.1 - 0.00021 21.4 0.1 0.00038 20.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPX74818.1 - 0.00026 20.9 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPX74818.1 - 0.001 18.8 0.5 0.0025 17.6 0.3 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EPX74818.1 - 0.0012 17.9 0.2 0.0018 17.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EPX74818.1 - 0.0031 16.6 0.3 0.0053 15.8 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPX74818.1 - 0.0041 15.6 1.5 0.0065 14.9 1.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EPX74818.1 - 0.017 14.0 0.2 0.024 13.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_7 PF12838.2 EPX74818.1 - 0.021 15.2 0.7 0.047 14.0 0.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pyr_redox PF00070.22 EPX74818.1 - 0.025 14.9 0.2 8.4 6.8 0.3 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPX74818.1 - 0.19 10.5 1.3 0.29 9.9 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EPX74818.1 - 0.51 8.9 1.4 2.9 6.4 0.5 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FCH PF00611.18 EPX74819.1 - 2e-17 63.1 0.5 2e-17 63.1 0.3 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EPX74819.1 - 8.9e-16 57.0 0.0 2.2e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPX74819.1 - 1.2e-14 53.6 0.0 2.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPX74819.1 - 1.2e-10 40.6 0.0 2.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TMF_TATA_bd PF12325.3 EPX74819.1 - 8.7 6.0 12.6 0.51 10.0 2.8 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Not1 PF04054.10 EPX74820.1 - 1.7e-109 366.1 3.1 1.7e-109 366.1 2.2 2.4 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EPX74820.1 - 1.1e-35 122.5 10.8 4e-35 120.6 7.5 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) ERG2_Sigma1R PF04622.7 EPX74821.1 - 4.8e-90 300.5 0.1 5.4e-90 300.3 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF3733 PF12534.3 EPX74822.1 - 0.042 13.1 1.1 0.073 12.3 0.0 1.8 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 DUF897 PF05982.7 EPX74822.1 - 0.059 12.1 0.0 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF897) DUF3087 PF11286.3 EPX74822.1 - 0.097 11.8 0.1 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) SNF2_N PF00176.18 EPX74823.1 - 1.4e-60 204.6 0.1 1.4e-60 204.6 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPX74823.1 - 1.3e-14 53.8 0.0 5.3e-14 51.8 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPX74823.1 - 3.4e-08 33.1 0.0 7.9e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPX74823.1 - 0.018 15.2 0.0 0.095 12.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF775 PF05603.7 EPX74823.1 - 0.44 10.0 4.4 3.5 7.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF775) GNAT_acetyltr_2 PF13718.1 EPX74824.1 - 7.6e-78 260.3 0.0 1.3e-77 259.5 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EPX74824.1 - 9.1e-65 217.5 0.0 2.3e-64 216.2 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EPX74824.1 - 5.4e-40 134.9 0.1 1.6e-39 133.4 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EPX74824.1 - 2.6e-31 107.7 0.5 8e-31 106.1 0.4 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_22 PF13401.1 EPX74824.1 - 0.0018 18.3 0.1 0.89 9.7 0.0 3.6 4 0 0 4 4 4 1 AAA domain Acetyltransf_1 PF00583.19 EPX74824.1 - 0.0037 17.2 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPX74824.1 - 0.014 15.5 0.0 0.053 13.6 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain APG6 PF04111.7 EPX74825.1 - 3e-95 318.8 5.3 3e-95 318.8 3.7 1.4 2 0 0 2 2 2 1 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 EPX74825.1 - 0.032 14.2 3.6 0.079 12.9 2.5 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain zf-AD PF07776.10 EPX74825.1 - 0.051 13.5 2.4 3.9 7.5 0.0 3.0 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Pyrophosphatase PF00719.14 EPX74826.1 - 3.1e-46 156.6 0.0 4.1e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase zf-RING_2 PF13639.1 EPX74827.1 - 1.7e-13 50.1 5.1 1.7e-13 50.1 3.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EPX74827.1 - 4.4e-08 32.7 3.4 4.4e-08 32.7 2.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPX74827.1 - 9.6e-08 31.9 5.0 9.6e-08 31.9 3.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX74827.1 - 3e-07 29.9 1.6 3e-07 29.9 1.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX74827.1 - 4.6e-07 29.3 4.7 4.6e-07 29.3 3.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPX74827.1 - 1.3e-06 28.4 10.7 6.8e-06 26.1 7.4 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPX74827.1 - 4e-05 23.3 6.0 0.00058 19.6 4.1 2.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EPX74827.1 - 0.0012 18.8 3.3 0.0056 16.7 2.3 2.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.1 EPX74827.1 - 0.0027 17.3 0.3 0.013 15.2 0.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.3 EPX74827.1 - 0.24 11.4 8.8 0.97 9.4 4.6 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.6 EPX74827.1 - 0.35 10.8 6.0 0.24 11.4 2.3 2.2 2 1 0 2 2 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EPX74827.1 - 0.88 9.4 11.8 0.61 10.0 4.0 3.0 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EPX74827.1 - 1.3 8.6 13.7 0.12 11.9 4.7 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RNase_P_p30 PF01876.11 EPX74828.1 - 2.3e-42 143.7 0.0 3.2e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Peptidase_M1 PF01433.15 EPX74829.1 - 4.9e-10 39.0 0.1 0.00045 19.4 0.0 3.2 2 1 0 2 2 2 2 Peptidase family M1 HEAT_2 PF13646.1 EPX74829.1 - 0.045 14.0 0.0 3.9 7.8 0.0 2.9 2 1 1 3 3 3 0 HEAT repeats Na_Ca_ex PF01699.19 EPX74830.1 - 7e-47 158.5 33.3 5.6e-24 84.3 10.3 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MRP-L27 PF09809.4 EPX74831.1 - 1.4e-13 50.4 0.1 1.6e-13 50.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 RNA_pol_L_2 PF13656.1 EPX74832.1 - 5.4e-25 86.6 0.5 7.1e-25 86.2 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EPX74832.1 - 2.3e-12 45.8 0.1 3e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain UreD PF01774.12 EPX74834.1 - 2.4e-50 170.9 0.0 2.8e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein Tic20 PF09685.5 EPX74835.1 - 0.66 9.9 9.0 1.3 9.0 6.2 1.6 1 1 0 1 1 1 0 Tic20-like protein DUF1625 PF07787.7 EPX74835.1 - 0.79 8.9 5.3 1.1 8.4 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Adeno_E3_CR2 PF02439.10 EPX74835.1 - 8.6 5.9 6.9 18 4.9 4.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 WTF PF03303.8 EPX74836.1 - 0.0024 17.3 2.9 0.0044 16.4 2.0 1.5 1 1 0 1 1 1 1 WTF protein DUF4577 PF15145.1 EPX74836.1 - 0.012 15.5 0.1 0.074 12.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) Acyl_transf_3 PF01757.17 EPX74836.1 - 0.02 13.7 8.8 0.026 13.3 6.1 1.0 1 0 0 1 1 1 0 Acyltransferase family MerE PF05052.7 EPX74836.1 - 0.12 12.3 0.2 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 MerE protein CRPA PF05745.6 EPX74836.1 - 0.84 9.4 4.9 1.5 8.6 0.7 2.2 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) UPF0104 PF03706.8 EPX74836.1 - 1.6 7.9 14.0 1.3 8.2 0.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0104) DUF1469 PF07332.6 EPX74836.1 - 3.5 7.3 5.9 27 4.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF912 PF06024.7 EPX74836.1 - 6.9 6.7 8.5 5.6 7.0 0.1 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3671 PF12420.3 EPX74836.1 - 7 6.6 10.2 0.66 9.9 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF2101 PF09874.4 EPX74837.1 - 0.061 12.7 0.8 0.084 12.3 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Lactamase_B_2 PF12706.2 EPX74839.1 - 5.4e-24 84.8 0.0 6.7e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPX74839.1 - 4.5e-11 42.7 0.0 5.8e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPX74839.1 - 0.019 14.5 0.1 0.03 13.9 0.0 1.4 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily WTF PF03303.8 EPX74840.1 - 0.01 15.2 0.5 0.01 15.2 0.3 2.0 1 1 1 2 2 2 0 WTF protein DUF2721 PF11026.3 EPX74840.1 - 0.14 11.8 0.1 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Gemini_mov PF01708.11 EPX74840.1 - 1.6 8.3 3.9 0.48 10.0 0.1 2.0 2 0 0 2 2 2 0 Geminivirus putative movement protein RRM_1 PF00076.17 EPX74841.1 - 9.1e-10 38.0 0.2 2.3e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74841.1 - 6.4e-08 32.3 0.0 1.3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74841.1 - 6.8e-07 29.1 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPX74841.1 - 0.0018 17.9 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EPX74841.1 - 0.0098 15.5 1.2 0.016 14.8 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4523 PF15023.1 EPX74841.1 - 0.037 13.5 1.7 0.062 12.8 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) Arc_PepC PF06819.6 EPX74841.1 - 0.2 11.5 4.8 0.32 10.9 2.4 1.9 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain ScpA_ScpB PF02616.9 EPX74841.1 - 2.5 7.6 7.6 0.21 11.1 1.8 1.7 2 0 0 2 2 2 0 ScpA/B protein Ribosomal_L18ae PF01775.12 EPX74842.1 - 3.5e-55 185.2 1.0 4.4e-55 184.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain ATP11 PF06644.6 EPX74843.1 - 5.9e-68 229.2 5.9 9.5e-68 228.5 4.1 1.3 1 0 0 1 1 1 1 ATP11 protein eIF3_subunit PF08597.5 EPX74844.1 - 9.4e-43 146.5 27.0 1.1e-42 146.3 18.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit EF-hand_1 PF00036.27 EPX74846.1 - 1.3e-39 130.4 8.2 5.5e-10 37.8 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EPX74846.1 - 9.3e-36 121.7 2.1 1.7e-19 69.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EPX74846.1 - 1.3e-33 114.3 9.1 1.8e-14 53.0 0.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EPX74846.1 - 4.9e-30 100.6 6.3 1.9e-09 36.5 0.0 4.7 4 2 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EPX74846.1 - 6.9e-26 88.4 5.8 1e-05 24.6 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EPX74846.1 - 6.6e-15 54.7 0.1 5.4e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EPX74846.1 - 1.6e-08 34.2 2.0 0.0037 16.9 0.0 2.9 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EPX74846.1 - 1.4e-06 28.2 0.0 0.0056 16.7 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 EPX74846.1 - 5.5e-06 26.2 0.3 5.4e-05 23.0 0.0 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 EPX74846.1 - 0.00031 20.2 0.0 1.1 8.8 0.0 2.8 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) TerB PF05099.8 EPX74846.1 - 0.00058 19.6 0.2 0.25 11.0 0.0 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF2267 PF10025.4 EPX74846.1 - 0.0034 17.4 0.1 2.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2267) Caleosin PF05042.8 EPX74846.1 - 0.0048 16.4 0.1 0.32 10.5 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein DUF3349 PF11829.3 EPX74846.1 - 0.0084 16.5 0.3 7 7.1 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) LNS2 PF08235.8 EPX74846.1 - 0.014 14.9 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DUF3807 PF12720.2 EPX74846.1 - 0.099 12.7 0.5 0.27 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Vps53_N PF04100.7 EPX74847.1 - 6.8e-94 314.7 11.4 6.8e-94 314.7 7.9 1.7 2 0 0 2 2 2 1 Vps53-like, N-terminal PhaP_Bmeg PF09602.5 EPX74847.1 - 0.022 14.5 6.4 0.47 10.2 1.3 3.2 3 0 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Tim17 PF02466.14 EPX74848.1 - 2e-33 115.1 4.7 2.4e-33 114.8 3.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PALP PF00291.20 EPX74849.1 - 8.2e-59 199.3 0.0 9.7e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme G6PD_C PF02781.11 EPX74850.1 - 2.1e-112 374.7 0.0 2.9e-112 374.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EPX74850.1 - 1.4e-63 214.4 0.0 2.1e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.19 EPX74851.1 - 1.8e-09 37.4 0.0 2.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPX74851.1 - 2.8e-08 33.7 0.0 3.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPX74851.1 - 3.3e-05 23.7 0.0 0.00043 20.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPX74851.1 - 8.5e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPX74851.1 - 0.0099 16.0 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPX74851.1 - 0.015 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPX74851.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec63 PF02889.11 EPX74852.1 - 2.1e-188 625.0 0.5 2.4e-107 358.7 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EPX74852.1 - 3.2e-49 166.6 1.2 5.7e-32 110.5 0.0 4.3 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 EPX74852.1 - 2.4e-16 60.1 0.0 3.8e-11 43.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPX74852.1 - 2e-12 46.7 0.1 1.7e-09 37.4 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPX74852.1 - 0.0017 18.5 0.1 0.094 12.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EPX74852.1 - 0.0052 16.0 0.0 3.5 6.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 EPX74852.1 - 0.029 14.4 0.0 6.3 6.8 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 EPX74852.1 - 9.4 6.4 8.1 45 4.2 0.0 3.8 3 1 0 3 3 3 0 AAA domain ResIII PF04851.10 EPX74853.1 - 1.9e-20 73.4 1.2 6.9e-20 71.6 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPX74853.1 - 2.4e-20 72.7 0.0 1.6e-19 70.0 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPX74853.1 - 9.2e-20 70.2 0.2 2.7e-19 68.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPX74853.1 - 0.0095 16.0 0.0 0.054 13.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain DUF2089 PF09862.4 EPX74853.1 - 0.038 13.7 0.2 0.15 11.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) Aldolase_II PF00596.16 EPX74854.1 - 5.5e-15 55.4 0.0 6.6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TGS PF02824.16 EPX74855.1 - 2.4e-21 75.2 0.0 4.5e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EPX74855.1 - 6e-19 68.1 0.1 1.3e-18 67.0 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPX74855.1 - 4.2e-11 42.3 0.2 1.4e-10 40.7 0.1 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPX74855.1 - 8.5e-05 22.4 0.1 0.26 11.0 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EPX74855.1 - 0.0074 16.7 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EPX74855.1 - 0.019 14.4 0.1 9.3 5.6 0.0 3.5 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain CCD PF07860.6 EPX74855.1 - 0.043 13.2 0.1 0.098 12.1 0.1 1.6 1 0 0 1 1 1 0 WisP family C-Terminal Region ArgK PF03308.11 EPX74855.1 - 0.046 12.4 0.2 0.1 11.3 0.1 1.6 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 EPX74855.1 - 0.047 14.5 0.1 0.49 11.2 0.1 2.4 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.11 EPX74855.1 - 0.055 12.5 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_28 PF13521.1 EPX74855.1 - 0.18 11.7 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain Steroid_dh PF02544.11 EPX74856.1 - 1.1e-27 96.6 5.8 5e-21 75.0 2.1 2.3 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EPX74856.1 - 1.7e-07 30.7 4.4 3.6e-07 29.7 3.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Meth_synt_2 PF01717.13 EPX74857.1 - 9.3e-144 478.3 0.0 4.1e-137 456.5 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EPX74857.1 - 3e-126 420.9 0.0 1.2e-115 386.0 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EPX74857.1 - 0.00023 20.2 0.0 0.53 9.1 0.0 2.7 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) Glucos_trans_II PF14264.1 EPX74858.1 - 0.0026 16.8 0.8 0.0033 16.4 0.5 1.1 1 0 0 1 1 1 1 Glucosyl transferase GtrII 7TM_GPCR_Srv PF10323.4 EPX74858.1 - 0.013 14.6 1.8 0.014 14.4 1.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Tmemb_18A PF09771.4 EPX74858.1 - 0.09 12.7 0.6 0.12 12.3 0.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 188 AA_permease_2 PF13520.1 EPX74859.1 - 4.2e-50 170.5 46.2 5.3e-50 170.1 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPX74859.1 - 1e-28 99.9 37.7 1.4e-28 99.4 26.1 1.1 1 0 0 1 1 1 1 Amino acid permease ATP12 PF07542.6 EPX74861.1 - 2.2e-32 111.5 0.0 3.2e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 ATP12 chaperone protein DUF572 PF04502.8 EPX74862.1 - 1.9e-67 227.8 10.3 2.1e-67 227.6 7.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Lar_restr_allev PF14354.1 EPX74862.1 - 0.011 15.9 0.5 0.9 9.8 0.3 2.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-FCS PF06467.9 EPX74862.1 - 0.022 14.4 2.0 0.074 12.7 0.7 2.1 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif RNA_pol_N PF01194.12 EPX74862.1 - 3.6 7.6 5.7 7.8 6.6 1.7 2.6 2 1 1 3 3 3 0 RNA polymerases N / 8 kDa subunit GPP34 PF05719.6 EPX74863.1 - 1.5e-63 214.6 0.1 1.9e-63 214.2 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Grp1_Fun34_YaaH PF01184.14 EPX74866.1 - 1.3e-73 246.7 18.3 1.7e-73 246.3 12.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family PXA PF02194.10 EPX74868.1 - 2.6e-08 33.6 2.1 0.00028 20.4 0.1 2.7 1 1 1 2 2 2 2 PXA domain Alg14 PF08660.6 EPX74869.1 - 7.9e-59 198.4 0.0 9.4e-59 198.2 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Med18 PF09637.5 EPX74870.1 - 4.8e-32 111.4 0.0 6.4e-31 107.7 0.0 1.9 1 1 0 1 1 1 1 Med18 protein Mem_trans PF03547.13 EPX74871.1 - 4.1e-70 236.0 2.9 5.3e-70 235.6 2.0 1.1 1 0 0 1 1 1 1 Membrane transport protein DUF819 PF05684.7 EPX74871.1 - 2.6 6.8 10.9 0.13 11.0 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF819) Nup54 PF13874.1 EPX74872.1 - 0.0062 16.2 1.4 0.065 12.8 0.9 2.4 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 Neugrin PF06413.6 EPX74872.1 - 0.16 11.7 3.6 0.27 11.0 2.5 1.2 1 0 0 1 1 1 0 Neugrin Ribosomal_S8 PF00410.14 EPX74873.1 - 4.2e-27 94.5 0.1 5.5e-27 94.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 RRM_6 PF14259.1 EPX74874.1 - 2.4e-14 53.0 0.0 6.6e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX74874.1 - 3.7e-08 32.8 0.0 7.2e-05 22.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 EPX74874.1 - 0.0049 15.9 1.2 0.011 14.8 0.9 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF3354 PF11834.3 EPX74874.1 - 0.05 13.2 0.2 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3354) HSP70 PF00012.15 EPX74875.1 - 6.3e-78 262.1 0.6 9.7e-78 261.5 0.4 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPX74875.1 - 3e-07 29.3 0.0 4.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Raptor_N PF14538.1 EPX74876.1 - 7e-68 227.3 0.0 1.5e-67 226.1 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EPX74876.1 - 4.3e-10 39.0 9.9 0.0057 16.4 0.2 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.17 EPX74876.1 - 3.3e-06 26.7 4.4 0.092 12.8 0.1 6.0 6 0 0 6 6 6 2 HEAT repeat BBS2_Mid PF14783.1 EPX74876.1 - 0.054 13.2 0.0 0.83 9.4 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Adaptin_N PF01602.15 EPX74877.1 - 3.6e-113 378.6 3.7 6.3e-113 377.8 2.5 1.4 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EPX74877.1 - 4.3e-47 159.7 4.2 7.5e-47 158.9 2.9 1.4 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EPX74877.1 - 2e-14 53.6 0.4 0.002 18.3 0.0 6.5 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.17 EPX74877.1 - 0.00054 19.8 2.7 5 7.4 0.2 5.2 5 0 0 5 5 5 1 HEAT repeat RICTOR_N PF14664.1 EPX74877.1 - 0.00068 18.3 0.4 0.0019 16.8 0.3 1.7 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term zf-RING_2 PF13639.1 EPX74878.1 - 9.3e-15 54.1 6.0 1.5e-14 53.5 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EPX74878.1 - 1.3e-11 44.0 0.0 2.4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 EPX74878.1 - 2.1e-09 37.3 0.7 4.4e-09 36.3 0.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPX74878.1 - 2.3e-09 37.1 6.2 4e-09 36.3 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX74878.1 - 8.2e-08 31.7 4.7 1.5e-07 30.9 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX74878.1 - 5.4e-07 29.1 3.9 1e-06 28.2 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX74878.1 - 8.3e-06 25.4 4.8 1.4e-05 24.6 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPX74878.1 - 0.00027 20.6 0.5 0.00054 19.7 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EPX74878.1 - 0.0012 18.5 1.4 0.003 17.2 1.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_1 PF14446.1 EPX74878.1 - 0.013 15.2 8.4 0.043 13.5 4.6 2.4 2 1 1 3 3 2 0 Prokaryotic RING finger family 1 Baculo_RING PF05883.6 EPX74878.1 - 0.014 15.2 0.5 0.031 14.0 0.4 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 EPX74878.1 - 0.033 13.7 4.2 0.06 12.9 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EPX74878.1 - 0.046 13.5 3.8 0.091 12.6 2.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EPX74878.1 - 0.13 12.3 5.1 0.28 11.2 3.5 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EPX74878.1 - 0.25 11.3 5.2 1.2 9.1 3.5 2.2 2 1 0 2 2 1 0 FANCL C-terminal domain PHD PF00628.24 EPX74878.1 - 0.71 9.6 5.1 1.5 8.5 3.5 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EPX74878.1 - 1.2 9.1 5.8 2.2 8.3 4.0 1.5 1 0 0 1 1 1 0 RING-like domain Metallophos PF00149.23 EPX74879.1 - 3.9e-39 134.1 0.2 5.5e-39 133.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase S-methyl_trans PF02574.11 EPX74880.1 - 1.5e-23 83.5 0.0 1.9e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Utp14 PF04615.8 EPX74881.1 - 3.6e-185 617.2 83.9 3.6e-185 617.2 58.2 2.1 1 1 1 2 2 2 1 Utp14 protein DUF2422 PF10337.4 EPX74882.1 - 1.6e-68 231.6 6.7 1.6e-68 231.6 4.7 4.2 3 2 1 4 4 4 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EPX74882.1 - 2.3e-65 220.4 0.0 9.3e-65 218.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EPX74882.1 - 3e-08 33.6 19.0 3e-08 33.6 13.2 2.8 3 0 0 3 3 3 1 Fusaric acid resistance protein-like RRM_1 PF00076.17 EPX74883.1 - 1.5e-87 287.2 4.2 8.8e-23 79.7 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74883.1 - 8.7e-58 192.2 0.6 2e-15 56.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74883.1 - 2.2e-44 149.1 0.1 6.8e-11 41.8 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EPX74883.1 - 4e-26 90.4 1.3 4e-26 90.4 0.9 2.7 4 0 0 4 4 4 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 EPX74883.1 - 7.1e-06 25.8 4.3 2.7 7.8 0.0 4.3 4 0 0 4 4 4 3 RNA binding motif CbiG_mid PF11761.3 EPX74883.1 - 6.6e-05 23.0 0.0 1.2 9.3 0.0 3.7 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 EPX74883.1 - 0.00013 21.6 4.4 0.013 15.2 0.3 3.5 4 0 0 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.1 EPX74883.1 - 0.00069 19.3 0.0 1.2 8.9 0.0 3.7 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif DnaI_N PF07319.6 EPX74883.1 - 0.007 16.5 1.5 0.61 10.3 0.5 3.3 3 0 0 3 3 3 1 Primosomal protein DnaI N-terminus OB_RNB PF08206.6 EPX74883.1 - 0.019 14.4 0.5 8.4 5.9 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.3 EPX74883.1 - 0.69 10.1 6.4 1.3 9.2 1.0 3.1 3 0 0 3 3 3 0 Heat induced stress protein YflT HECT PF00632.20 EPX74884.1 - 2.8e-92 309.2 0.0 6.4e-92 308.0 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ftsk_gamma PF09397.5 EPX74884.1 - 0.053 13.2 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Ftsk gamma domain Usp PF00582.21 EPX74886.1 - 1.9e-18 66.9 1.5 8.9e-17 61.5 0.4 3.2 2 1 0 2 2 2 1 Universal stress protein family Pam17 PF08566.5 EPX74887.1 - 1.7e-63 213.4 0.3 2.2e-63 213.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF3613 PF12266.3 EPX74887.1 - 0.26 10.8 0.1 0.26 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) SART-1 PF03343.8 EPX74888.1 - 3.2e-112 375.9 75.2 3.7e-112 375.7 52.1 1.0 1 0 0 1 1 1 1 SART-1 family Prenyltrans PF00432.16 EPX74889.1 - 1.6e-59 197.0 4.1 2.8e-13 49.1 0.1 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPX74889.1 - 3.7e-39 133.6 0.0 2.8e-15 56.6 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPX74889.1 - 1e-08 35.1 0.0 5.9e-05 23.0 0.0 3.8 3 1 1 4 4 4 2 Prenyltransferase-like Peptidase_M20 PF01546.23 EPX74889.1 - 0.036 13.5 0.0 0.056 12.9 0.0 1.3 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 A2M_comp PF07678.9 EPX74889.1 - 0.043 13.0 0.1 20 4.2 0.0 3.8 4 1 0 4 4 4 0 A-macroglobulin complement component Pga1 PF10333.4 EPX74890.1 - 0.0028 17.3 0.9 0.0098 15.5 0.6 1.9 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Ribonuc_2-5A PF06479.7 EPX74891.1 - 4.1e-46 156.0 0.2 1.1e-45 154.6 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.20 EPX74891.1 - 6.8e-41 140.1 0.0 1.3e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74891.1 - 1.9e-21 76.3 0.0 3.3e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 EPX74891.1 - 4.4e-06 26.3 0.0 0.00033 20.1 0.0 2.6 1 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.16 EPX74891.1 - 1.2e-05 24.5 0.0 0.79 9.3 0.0 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat 4F5 PF04419.9 EPX74892.1 - 1.2e-05 25.9 8.4 1.2e-05 25.9 5.8 2.2 2 0 0 2 2 2 1 4F5 protein family TRIQK PF15168.1 EPX74892.1 - 0.035 14.0 2.1 0.054 13.4 1.5 1.3 1 1 0 1 1 1 0 Triple QxxK/R motif-containing protein family Recep_L_domain PF01030.19 EPX74893.1 - 2.4e-10 40.3 9.1 0.00093 19.1 0.1 4.8 2 1 4 6 6 6 3 Receptor L domain LRR_5 PF13306.1 EPX74893.1 - 0.0021 17.7 7.6 0.12 12.0 0.0 3.2 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) Ecm33 PF12454.3 EPX74893.1 - 0.015 15.1 0.2 0.049 13.5 0.1 1.9 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein RAP1 PF07218.6 EPX74893.1 - 0.34 8.9 14.2 0.77 7.7 9.9 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-rbx1 PF12678.2 EPX74894.1 - 6.5e-36 122.2 13.3 8.1e-36 121.9 9.2 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPX74894.1 - 2.4e-18 65.7 9.6 3.2e-18 65.3 6.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EPX74894.1 - 4.5e-08 32.8 11.7 4.9e-07 29.4 8.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPX74894.1 - 0.00016 21.2 11.4 0.0014 18.2 7.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX74894.1 - 0.00034 20.2 9.5 0.0014 18.2 2.7 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPX74894.1 - 0.014 15.3 11.9 0.21 11.6 8.3 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4001 PF13165.1 EPX74894.1 - 0.13 11.9 3.6 0.19 11.4 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4001) zf-HC5HC2H PF13771.1 EPX74894.1 - 0.18 11.9 10.0 11 6.2 6.9 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.1 EPX74894.1 - 0.19 11.4 11.4 1.6 8.5 7.9 2.2 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 EPX74894.1 - 0.4 10.6 9.1 1.4 8.9 6.3 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 EPX74894.1 - 0.4 10.6 9.6 1.1 9.2 6.7 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 EPX74894.1 - 0.53 10.0 6.8 11 5.7 4.7 2.2 1 1 0 1 1 1 0 RING-type zinc-finger Pkinase PF00069.20 EPX74895.1 - 4.4e-61 206.3 0.0 6e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74895.1 - 4.9e-30 104.4 0.0 1.2e-29 103.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX74895.1 - 0.00014 20.9 0.0 0.00028 19.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EPX74895.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2363 PF10155.4 EPX74896.1 - 0.0049 16.8 0.4 0.0088 15.9 0.3 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) DUF663 PF04950.7 EPX74897.1 - 8.4e-105 349.9 0.2 2.4e-104 348.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EPX74897.1 - 4.5e-19 67.7 0.0 1e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain MutL_C PF08676.6 EPX74897.1 - 0.13 11.8 0.7 0.25 10.9 0.5 1.4 1 0 0 1 1 1 0 MutL C terminal dimerisation domain Vps39_1 PF10366.4 EPX74898.1 - 1.1e-27 96.1 0.3 5.7e-27 93.8 0.1 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EPX74898.1 - 2.1e-27 95.4 0.6 5.4e-27 94.1 0.4 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EPX74898.1 - 4.5e-18 65.6 0.4 1.1e-17 64.3 0.3 1.6 1 0 0 1 1 1 1 CNH domain TPR_19 PF14559.1 EPX74898.1 - 7.3e-05 23.0 0.1 1.3 9.3 0.0 5.5 6 1 1 7 7 7 1 Tetratricopeptide repeat Clathrin PF00637.15 EPX74898.1 - 7.8e-05 22.3 2.5 0.00047 19.7 0.2 3.2 3 0 0 3 3 3 1 Region in Clathrin and VPS PPR PF01535.15 EPX74898.1 - 0.0062 16.4 0.0 33 4.7 0.0 4.0 3 0 0 3 3 3 0 PPR repeat PPR_2 PF13041.1 EPX74898.1 - 0.031 14.2 0.0 4.4 7.3 0.0 3.4 3 0 0 3 3 3 0 PPR repeat family DUF4050 PF13259.1 EPX74899.1 - 6.2e-15 55.1 1.9 6.9e-15 55.0 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) ATP-synt_B PF00430.13 EPX74900.1 - 0.0071 16.1 1.7 0.018 14.8 1.2 1.7 1 1 0 1 1 1 1 ATP synthase B/B' CF(0) MRG PF05712.8 EPX74901.1 - 9.3e-48 161.7 0.2 1.7e-47 160.8 0.1 1.4 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EPX74901.1 - 1.3e-10 40.7 0.5 2.6e-10 39.8 0.4 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Atrophin-1 PF03154.10 EPX74901.1 - 0.33 9.0 9.6 0.45 8.6 6.7 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF4544 PF15077.1 EPX74901.1 - 2.2 7.7 4.9 3.3 7.1 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Cnl2_NKP2 PF09447.5 EPX74902.1 - 5.8e-20 70.7 2.2 5.8e-20 70.7 1.5 1.9 2 0 0 2 2 2 1 Cnl2/NKP2 family protein DUF2115 PF09888.4 EPX74902.1 - 0.055 13.5 1.1 0.11 12.5 0.8 1.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF3967 PF13152.1 EPX74902.1 - 0.072 12.7 1.1 0.24 11.0 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3967) IZUMO PF15005.1 EPX74902.1 - 0.16 12.0 1.0 3.9 7.4 0.0 2.3 1 1 2 3 3 3 0 Izumo sperm-egg fusion THOC7 PF05615.8 EPX74902.1 - 0.22 11.7 4.5 0.94 9.7 2.5 1.8 1 1 1 2 2 2 0 Tho complex subunit 7 HK PF02110.10 EPX74903.1 - 1.5e-87 292.8 0.4 2.2e-87 292.3 0.3 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EPX74903.1 - 5.6e-59 198.2 1.4 8.2e-59 197.7 1.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Peptidase_M24 PF00557.19 EPX74904.1 - 1.2e-26 93.5 0.0 1.4e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF1905 PF08922.6 EPX74904.1 - 0.031 13.8 0.0 2.3 7.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) DUF1762 PF08574.5 EPX74905.1 - 7.1e-08 32.7 13.0 2.6e-07 30.9 9.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1762) SRPRB PF09439.5 EPX74906.1 - 1.6e-31 108.9 0.0 2e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EPX74906.1 - 5.6e-11 41.9 0.2 1.8e-10 40.3 0.1 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPX74906.1 - 4.2e-09 36.1 0.1 4.7e-06 26.1 0.1 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPX74906.1 - 1e-05 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EPX74906.1 - 0.00014 21.1 0.2 0.00024 20.3 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EPX74906.1 - 0.00047 19.4 0.0 0.00095 18.4 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.15 EPX74906.1 - 0.0015 17.2 0.8 0.052 12.2 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit NACHT PF05729.7 EPX74906.1 - 0.0024 17.5 0.0 1.9 8.1 0.0 2.4 2 1 0 2 2 2 2 NACHT domain AAA_29 PF13555.1 EPX74906.1 - 0.0052 16.2 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ras PF00071.17 EPX74906.1 - 0.0061 15.9 0.2 0.048 13.0 0.1 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EPX74906.1 - 0.0095 16.4 0.0 0.021 15.2 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein AAA_33 PF13671.1 EPX74906.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EPX74906.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EPX74906.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPX74906.1 - 0.014 16.1 0.0 0.026 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EPX74906.1 - 0.016 14.6 0.3 3.1 7.2 0.0 2.4 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EPX74906.1 - 0.023 14.4 0.6 0.52 10.1 0.0 2.6 2 1 1 3 3 3 0 Dynamin family Arch_ATPase PF01637.13 EPX74906.1 - 0.03 14.0 0.1 0.056 13.1 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase SRP54 PF00448.17 EPX74906.1 - 0.031 13.7 0.1 36 3.7 0.0 3.0 2 1 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EPX74906.1 - 0.031 14.1 0.0 0.051 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EPX74906.1 - 0.032 13.7 0.8 0.57 9.6 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 EPX74906.1 - 0.032 13.9 0.1 0.085 12.5 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EPX74906.1 - 0.22 11.8 3.6 1.7 8.8 2.5 2.0 1 1 0 1 1 1 0 AAA domain Gln-synt_C PF00120.19 EPX74907.1 - 2e-61 207.3 0.0 2.5e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EPX74907.1 - 3.3e-19 68.2 0.0 5.5e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain tRNA_Me_trans PF03054.11 EPX74909.1 - 1.7e-120 401.8 0.0 2e-120 401.6 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 EPX74909.1 - 0.00011 21.7 0.0 0.00049 19.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.15 EPX74909.1 - 0.0013 18.2 0.0 0.021 14.3 0.0 2.3 2 0 0 2 2 2 1 PP-loop family NAD_synthase PF02540.12 EPX74909.1 - 0.0021 17.0 0.0 0.041 12.7 0.0 2.2 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.16 EPX74909.1 - 0.005 16.3 0.0 0.0088 15.5 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase Diphthamide_syn PF01866.12 EPX74909.1 - 0.21 10.8 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative diphthamide synthesis protein EMP24_GP25L PF01105.19 EPX74910.1 - 3.1e-35 121.5 0.4 3.7e-35 121.3 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.20 EPX74911.1 - 1.6e-67 227.4 0.0 2.2e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX74911.1 - 7.1e-34 117.0 0.0 1e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX74911.1 - 6.2e-06 25.3 0.1 1.3e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPX74911.1 - 7.4e-06 25.1 0.1 1.3e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Oxysterol_BP PF01237.13 EPX74913.1 - 6.1e-101 337.4 0.0 1.8e-100 335.8 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EPX74913.1 - 4.3e-36 122.8 0.1 1.1e-35 121.4 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EPX74913.1 - 0.00036 20.7 0.1 0.0017 18.6 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain TPR_11 PF13414.1 EPX74914.1 - 2.3e-08 33.5 5.4 0.0044 16.6 0.1 3.4 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 EPX74914.1 - 2.2e-06 27.5 8.7 0.011 15.6 0.1 4.4 2 2 4 6 6 6 4 Tetratricopeptide repeat SNAP PF14938.1 EPX74914.1 - 3.4e-05 23.1 6.1 0.0078 15.3 0.1 3.0 1 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_8 PF13181.1 EPX74914.1 - 0.0002 20.9 0.0 0.0023 17.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPX74914.1 - 0.00049 19.5 6.9 0.0014 18.1 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPX74914.1 - 0.0013 18.4 0.3 0.0013 18.4 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPX74914.1 - 0.0036 17.9 1.2 0.076 13.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.4 EPX74914.1 - 0.0089 15.5 1.3 1.3 8.4 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_14 PF13428.1 EPX74914.1 - 0.011 16.2 0.9 3.6 8.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3263 PF11662.3 EPX74914.1 - 0.042 13.3 0.2 0.43 10.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) TPR_17 PF13431.1 EPX74914.1 - 0.056 13.6 2.2 1.7 9.0 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPX74914.1 - 0.06 13.1 7.0 0.48 10.3 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EPX74914.1 - 0.096 12.5 5.0 0.29 11.0 0.1 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain FtsA PF14450.1 EPX74914.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Cell division protein FtsA TPR_6 PF13174.1 EPX74914.1 - 0.21 12.1 4.4 0.77 10.3 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat D123 PF07065.9 EPX74915.1 - 5.7e-85 284.9 0.0 6.6e-85 284.7 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 EPX74915.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) PsaD PF02531.11 EPX74915.1 - 0.13 11.5 0.0 8.4 5.5 0.0 2.6 2 0 0 2 2 2 0 PsaD dCMP_cyt_deam_1 PF00383.17 EPX74916.1 - 8.6e-11 41.4 0.5 1.4e-10 40.6 0.3 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DGCR6 PF07324.6 EPX74916.1 - 0.11 11.9 1.1 0.19 11.1 0.7 1.3 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Bd3614-deam PF14439.1 EPX74916.1 - 0.21 11.4 1.3 0.52 10.1 0.9 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase Clathrin PF00637.15 EPX74917.1 - 1.7e-14 53.6 2.8 5.5e-14 51.9 0.1 3.2 4 1 0 4 4 4 1 Region in Clathrin and VPS WD40 PF00400.27 EPX74917.1 - 0.00076 19.2 0.2 0.076 12.9 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 EPX74917.1 - 0.01 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Clat_adaptor_s PF01217.15 EPX74918.1 - 4.6e-54 181.9 1.1 6e-54 181.6 0.8 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.20 EPX74919.1 - 2.4e-08 33.4 0.0 3.3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EPX74919.1 - 4.9e-07 29.0 0.0 1.9e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPX74919.1 - 5.3e-07 29.1 0.0 8.6e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.15 EPX74919.1 - 1.1e-05 24.7 0.0 5.4e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 Ecdysteroid kinase APH PF01636.18 EPX74919.1 - 0.00019 21.2 0.0 0.00083 19.1 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EPX74919.1 - 0.0021 17.1 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NRDE-2 PF08424.5 EPX74919.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference HTH_12 PF08461.5 EPX74920.1 - 0.03 14.0 0.1 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain GTP_cyclohydro2 PF00925.15 EPX74921.1 - 1.2e-59 200.3 0.2 4.4e-55 185.5 0.1 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Nup188 PF10487.4 EPX74922.1 - 1.2e-51 175.7 17.6 2e-51 175.0 12.2 1.2 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Hid1 PF12722.2 EPX74923.1 - 1.7e-113 380.1 34.2 5.2e-81 272.6 13.4 2.1 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Nop10p PF04135.7 EPX74924.1 - 4.3e-22 77.5 1.3 4.9e-22 77.4 0.9 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PBCV_basic_adap PF08789.5 EPX74924.1 - 0.13 11.9 0.3 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 PBCV-specific basic adaptor domain GIY-YIG PF01541.19 EPX74925.1 - 4.3e-09 36.6 0.0 5.4e-08 33.0 0.0 2.4 1 1 1 2 2 2 1 GIY-YIG catalytic domain zf-RING_2 PF13639.1 EPX74925.1 - 0.9 9.4 13.8 5.3 6.9 10.0 2.0 1 1 1 2 2 2 0 Ring finger domain GHMP_kinases_N PF00288.21 EPX74926.1 - 3.5e-10 39.8 0.2 7.7e-10 38.7 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPX74926.1 - 2.8e-06 27.4 0.0 7.2e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal ALIX_LYPXL_bnd PF13949.1 EPX74926.1 - 0.036 13.0 0.3 0.055 12.4 0.2 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV YcbB PF08664.5 EPX74926.1 - 0.066 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 YcbB domain IncA PF04156.9 EPX74926.1 - 0.45 10.0 3.6 0.21 11.1 0.8 1.6 2 0 0 2 2 2 0 IncA protein Ribosomal_L19 PF01245.15 EPX74927.1 - 5.7e-23 80.8 0.1 8.4e-23 80.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 zf-Apc11 PF12861.2 EPX74928.1 - 2.1e-45 152.5 10.4 2.3e-45 152.3 7.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EPX74928.1 - 1.6e-30 105.0 10.2 1.8e-30 104.8 7.1 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPX74928.1 - 2.2e-07 30.5 13.2 2.2e-06 27.4 9.2 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPX74928.1 - 1.1e-05 25.4 5.0 1.1e-05 25.4 3.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX74928.1 - 5.5e-05 22.8 9.4 0.0015 18.1 6.7 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 EPX74928.1 - 0.018 14.5 3.5 0.034 13.6 2.4 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 EPX74928.1 - 0.022 14.3 12.2 0.11 12.1 8.4 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EPX74928.1 - 0.075 12.8 0.6 0.075 12.8 0.4 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-HC5HC2H_2 PF13832.1 EPX74928.1 - 0.19 11.7 6.6 0.35 10.8 4.6 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 EPX74928.1 - 1.4 8.9 15.6 6.3 6.8 10.3 2.6 1 1 1 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 EPX74928.1 - 4.5 7.4 10.3 1.6 8.8 4.3 2.2 2 1 0 2 2 2 0 RING-variant domain zf-RING-like PF08746.6 EPX74928.1 - 5.2 7.1 10.0 16 5.6 6.9 1.9 1 1 0 1 1 1 0 RING-like domain WD40 PF00400.27 EPX74929.1 - 8.5e-43 142.7 13.6 4.8e-09 35.7 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EPX74929.1 - 0.00038 20.2 0.5 0.042 13.5 0.1 3.3 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF249 PF03158.8 EPX74929.1 - 0.0028 17.1 0.8 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 Multigene family 530 protein Cytochrom_D1 PF02239.11 EPX74929.1 - 0.087 11.0 0.1 0.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain ATP-synt_ab PF00006.20 EPX74932.1 - 5.1e-114 379.1 0.0 7.1e-114 378.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPX74932.1 - 3.4e-24 85.4 0.3 7e-24 84.4 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPX74932.1 - 9.2e-15 54.6 0.9 2.3e-14 53.3 0.6 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 EPX74932.1 - 0.072 12.9 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Scramblase PF03803.10 EPX74933.1 - 3.1e-71 238.9 0.0 3.8e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 Scramblase RRM_1 PF00076.17 EPX74934.1 - 6e-25 86.6 0.3 3.8e-12 45.6 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX74934.1 - 1.9e-21 75.7 0.0 3.8e-09 36.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX74934.1 - 4.1e-13 48.9 3.6 1.5e-06 27.9 0.1 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FmdE PF02663.9 EPX74934.1 - 0.099 12.5 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Ribosomal_S6 PF01250.12 EPX74935.1 - 4e-11 42.5 0.0 7e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S6 SEP PF08059.8 EPX74936.1 - 1.5e-26 92.4 0.1 1.2e-25 89.6 0.0 2.5 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 EPX74936.1 - 7.8e-10 38.6 0.0 1.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EPX74936.1 - 0.00026 20.4 0.1 0.00047 19.6 0.1 1.3 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.8 EPX74936.1 - 0.36 10.2 1.6 0.33 10.3 0.1 1.7 2 0 0 2 2 2 0 TAP C-terminal domain MTHFR PF02219.12 EPX74937.1 - 1.8e-109 365.3 0.0 2.5e-109 364.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PLU-1 PF08429.6 EPX74938.1 - 1.9e-62 211.1 16.8 5.3e-58 196.5 11.4 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EPX74938.1 - 2.3e-25 89.0 0.5 1.3e-24 86.5 0.0 2.7 3 0 0 3 3 3 1 JmjC domain, hydroxylase PHD PF00628.24 EPX74938.1 - 5.4e-20 70.8 45.8 6.8e-08 32.0 6.7 4.1 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.11 EPX74938.1 - 4.7e-09 36.1 0.1 4.7e-09 36.1 0.1 3.3 2 0 0 2 2 2 1 C5HC2 zinc finger Prok-RING_1 PF14446.1 EPX74938.1 - 0.00054 19.6 12.7 0.0019 17.9 2.0 4.5 5 1 1 6 6 6 2 Prokaryotic RING finger family 1 C1_1 PF00130.17 EPX74938.1 - 0.0009 18.9 30.6 0.13 12.0 1.5 4.4 4 0 0 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_3 PF13922.1 EPX74938.1 - 5.2 7.3 12.5 0.64 10.2 0.3 3.4 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx zf-PHD-like PF15446.1 EPX74938.1 - 6.2 6.0 23.2 2.8 7.2 1.4 3.7 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Ferritin_2 PF13668.1 EPX74939.1 - 9.3e-17 61.2 0.2 1.4e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain ABC_trans_N PF14510.1 EPX74939.1 - 0.095 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal GatB_N PF02934.10 EPX74940.1 - 5.2e-87 291.3 0.0 4.2e-53 180.0 0.0 2.1 1 1 1 2 2 2 2 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EPX74940.1 - 3.7e-29 101.3 0.1 6.1e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 GatB domain IF-2B PF01008.12 EPX74941.1 - 7.6e-70 235.0 0.0 9e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Orbi_VP3 PF01700.11 EPX74941.1 - 4.9e-06 24.3 0.1 6.3e-06 23.9 0.1 1.1 1 0 0 1 1 1 1 Orbivirus VP3 (T2) protein Lum_binding PF00677.12 EPX74941.1 - 0.038 13.8 0.2 0.093 12.6 0.2 1.6 1 0 0 1 1 1 0 Lumazine binding domain IPPT PF01715.12 EPX74942.1 - 1e-65 221.2 0.1 2.4e-65 220.0 0.0 1.6 2 0 0 2 2 2 1 IPP transferase AAA_17 PF13207.1 EPX74942.1 - 1.9e-07 31.9 0.1 8e-07 29.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain IPT PF01745.11 EPX74942.1 - 1.3e-06 27.8 0.0 1.7e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Isopentenyl transferase AAA_18 PF13238.1 EPX74942.1 - 1.8e-05 25.0 0.7 0.00042 20.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EPX74942.1 - 0.00017 21.4 0.3 0.0014 18.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EPX74942.1 - 0.0022 17.8 0.1 0.01 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 EPX74942.1 - 0.0024 17.4 0.0 0.0058 16.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EPX74942.1 - 0.003 17.6 0.0 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPX74942.1 - 0.012 14.6 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF3449 PF11931.3 EPX74942.1 - 0.017 14.6 0.0 0.044 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Hpr_kinase_C PF07475.7 EPX74942.1 - 0.023 14.0 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Cytidylate_kin2 PF13189.1 EPX74942.1 - 0.032 14.1 0.0 0.032 14.1 0.0 2.0 3 0 0 3 3 3 0 Cytidylate kinase-like family Arch_ATPase PF01637.13 EPX74942.1 - 0.084 12.5 0.5 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase SKI PF01202.17 EPX74942.1 - 0.15 11.8 0.2 0.15 11.8 0.1 2.9 3 1 0 3 3 3 0 Shikimate kinase zf-met PF12874.2 EPX74942.1 - 0.41 10.9 2.9 2.9 8.2 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Aconitase PF00330.15 EPX74943.1 - 5.9e-73 245.9 0.0 2.1e-45 155.0 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPX74943.1 - 1e-24 87.1 0.0 1.8e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain WD40 PF00400.27 EPX74944.1 - 1.7e-19 68.8 15.1 1.3e-05 24.8 0.2 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 EPX74945.1 - 4.8e-07 29.6 8.5 7.1e-07 29.1 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPX74945.1 - 5.4e-07 29.1 7.1 8.3e-07 28.5 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPX74945.1 - 3.3e-06 26.6 4.7 6e-06 25.8 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX74945.1 - 2.4e-05 23.9 8.8 3.7e-05 23.3 6.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPX74945.1 - 3.7e-05 23.4 7.7 5.8e-05 22.8 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 EPX74945.1 - 0.0014 17.8 0.6 0.0019 17.4 0.4 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-rbx1 PF12678.2 EPX74945.1 - 0.0027 17.7 0.6 0.0048 16.9 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger DUF581 PF04570.9 EPX74945.1 - 0.0074 15.5 0.8 0.019 14.2 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF581) zf-C3HC4_4 PF15227.1 EPX74945.1 - 0.011 15.6 3.8 0.011 15.6 2.6 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPX74945.1 - 0.017 14.8 5.3 0.046 13.4 3.4 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EPX74945.1 - 0.034 13.9 2.6 0.034 13.9 1.8 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EPX74945.1 - 0.063 12.8 5.2 0.1 12.2 3.6 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 EPX74945.1 - 1.3 8.9 7.6 6.6 6.7 5.4 1.9 1 1 1 2 2 2 0 FYVE zinc finger PI3_PI4_kinase PF00454.22 EPX74946.1 - 1.6e-38 132.4 0.2 3.1e-38 131.5 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PGAP1 PF07819.8 EPX74947.1 - 7.7e-79 264.4 0.0 1.2e-78 263.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EPX74947.1 - 1.5e-06 27.9 0.0 3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPX74947.1 - 0.00015 21.7 0.1 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPX74947.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PSI_PsaH PF03244.9 EPX74947.1 - 0.12 11.6 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI DUF2034 PF10356.4 EPX74948.1 - 4e-31 107.6 0.1 1.3e-16 60.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EPX74948.1 - 2.2e-13 50.0 0.0 3.2e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease GDA1_CD39 PF01150.12 EPX74949.1 - 1.7e-97 326.6 0.0 2.2e-97 326.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Lactamase_B PF00753.22 EPX74950.1 - 6.1e-29 101.0 0.5 7.6e-29 100.7 0.4 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPX74950.1 - 3.9e-05 23.2 0.4 9.2e-05 22.0 0.3 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPX74950.1 - 0.003 17.2 0.2 0.0062 16.2 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pam16 PF03656.8 EPX74951.1 - 2.7e-06 27.1 0.1 5.1e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.26 EPX74951.1 - 3.8e-06 26.5 0.0 7.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.1 EPX74951.1 - 0.42 9.9 2.6 0.98 8.7 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Vps16_N PF04841.8 EPX74952.1 - 1.3e-126 422.4 0.0 2.1e-126 421.7 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EPX74952.1 - 8.2e-115 383.1 6.7 8.2e-115 383.1 4.6 1.5 2 0 0 2 2 2 1 Vps16, C-terminal region WD40 PF00400.27 EPX74953.1 - 4.8e-16 57.9 2.2 7e-08 32.0 0.0 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EPX74953.1 - 0.088 11.5 0.0 1.1 7.8 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like DUF2027 PF09640.5 EPX74953.1 - 0.15 11.4 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) Copper-fist PF00649.13 EPX74954.1 - 2.2e-19 68.3 2.4 2.2e-19 68.3 1.6 1.9 2 0 0 2 2 2 1 Copper fist DNA binding domain Ran-binding PF05508.6 EPX74955.1 - 1.1e-89 300.3 0.2 1.8e-89 299.6 0.2 1.3 1 0 0 1 1 1 1 RanGTP-binding protein Colicin PF01024.14 EPX74955.1 - 0.049 13.2 0.3 0.12 11.8 0.2 1.7 1 0 0 1 1 1 0 Colicin pore forming domain Arrestin_C PF02752.17 EPX74956.1 - 7.6e-22 77.8 0.0 2.7e-19 69.6 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EPX74956.1 - 3.3e-20 72.4 0.0 1.6e-19 70.2 0.0 2.1 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EPX74956.1 - 0.00023 20.7 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like SNARE PF05739.14 EPX74957.1 - 0.056 13.1 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 SNARE domain PEMT PF04191.8 EPX74957.1 - 0.081 13.0 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipid methyltransferase DUF3337 PF11816.3 EPX74958.1 - 2.4e-51 175.1 2.3 1.7e-47 162.4 2.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EPX74958.1 - 8.3e-21 73.0 24.5 1.3e-08 34.3 0.1 7.3 8 0 0 8 8 8 4 WD domain, G-beta repeat DUF2036 PF09724.4 EPX74959.1 - 9.3e-40 136.7 6.5 1.9e-39 135.7 4.5 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) RhoGEF PF00621.15 EPX74960.1 - 3.1e-28 98.8 1.6 3.1e-28 98.8 1.1 2.0 2 0 0 2 2 2 1 RhoGEF domain RhoGAP PF00620.22 EPX74960.1 - 0.047 13.2 1.8 0.072 12.7 0.4 1.9 2 0 0 2 2 2 0 RhoGAP domain Proteasome PF00227.21 EPX74961.1 - 1.7e-58 197.0 0.1 2.1e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPX74961.1 - 3.9e-14 51.6 0.2 7e-14 50.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1896 PF08989.5 EPX74961.1 - 0.11 12.3 0.3 1.1 9.0 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1896) Rad60-SLD PF11976.3 EPX74961.1 - 0.15 11.7 1.3 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like FF PF01846.14 EPX74962.1 - 4.3e-13 48.9 0.9 1.3e-11 44.2 0.1 3.2 2 0 0 2 2 2 1 FF domain WW PF00397.21 EPX74962.1 - 2.2e-12 46.5 9.3 5.5e-06 26.1 0.9 2.6 2 0 0 2 2 2 2 WW domain RNA_pol_3_Rpc31 PF11705.3 EPX74962.1 - 6.2 6.6 24.9 0.05 13.5 10.0 2.5 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Tht1 PF04163.7 EPX74963.1 - 6e-51 173.4 25.3 8e-51 173.0 17.5 1.0 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein GATase PF00117.23 EPX74964.1 - 1.6e-15 57.0 0.0 2.1e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPX74964.1 - 0.00032 20.1 0.1 0.0024 17.3 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 EPX74964.1 - 0.0021 17.6 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain PGM_PMM_I PF02878.11 EPX74965.1 - 8.3e-17 60.9 0.0 1.1e-09 37.9 0.0 2.4 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 EPX74965.1 - 3e-11 43.1 0.2 8.2e-11 41.7 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 EPX74965.1 - 1.9e-08 34.5 0.0 6.2e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EPX74965.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Mre11_DNA_bind PF04152.9 EPX74966.1 - 6e-55 185.7 0.7 6e-55 185.7 0.5 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EPX74966.1 - 5.6e-29 100.9 2.3 1.1e-28 100.0 1.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPX74966.1 - 4.5e-07 29.8 0.2 2.7e-06 27.3 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GATA PF00320.22 EPX74967.1 - 5.1e-31 105.7 18.3 1.2e-16 59.6 2.4 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EPX74967.1 - 0.02 14.2 8.8 0.77 9.1 0.2 2.8 2 0 0 2 2 2 0 TFIIB zinc-binding eIF-5_eIF-2B PF01873.12 EPX74967.1 - 0.097 12.3 9.6 1.1 8.9 0.5 2.9 3 0 0 3 3 3 0 Domain found in IF2B/IF5 Amino_oxidase PF01593.19 EPX74968.1 - 6.4e-25 88.1 2.4 1.1e-23 84.0 0.0 3.8 3 1 0 3 3 3 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EPX74968.1 - 4.4e-12 45.9 0.0 1.3e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EPX74968.1 - 4.3e-06 26.6 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EPX74968.1 - 9.2e-05 22.6 1.2 0.0003 20.9 0.9 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box Pyr_redox_3 PF13738.1 EPX74968.1 - 0.0029 17.6 0.0 0.13 12.2 0.0 2.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPX74968.1 - 0.0032 17.2 0.0 1.1 8.9 0.0 3.0 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EPX74968.1 - 0.0072 15.2 0.0 0.029 13.2 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Arrestin_N PF00339.24 EPX74969.1 - 1.8e-06 27.8 0.0 4.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain UPF0227 PF05728.7 EPX74969.1 - 0.2 11.3 1.2 0.46 10.1 0.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF221 PF02714.10 EPX74970.1 - 2.8e-102 341.9 16.2 2.8e-102 341.9 11.2 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPX74970.1 - 3e-45 153.6 3.2 3e-45 153.6 2.2 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EPX74970.1 - 4.5e-17 61.7 0.0 1.1e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EPX74970.1 - 1.7e-16 60.4 3.7 3.9e-16 59.3 2.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Kinesin-relat_1 PF12711.2 EPX74970.1 - 0.037 14.4 0.1 0.21 12.0 0.0 2.1 2 0 0 2 2 2 0 Kinesin motor DUF4618 PF15397.1 EPX74970.1 - 0.056 12.7 2.9 0.1 11.9 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) ThiF PF00899.16 EPX74971.1 - 1.7e-36 125.0 1.4 2e-36 124.8 0.0 1.7 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EPX74971.1 - 4.3e-22 77.4 0.4 9.4e-22 76.3 0.3 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EPX74971.1 - 2.2e-16 58.9 2.3 4.2e-16 58.0 1.6 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E2_bind PF08825.5 EPX74971.1 - 6.9e-13 48.1 0.6 1.7e-12 46.9 0.4 1.7 1 0 0 1 1 1 1 E2 binding domain MoeZ_MoeB PF05237.8 EPX74971.1 - 0.00049 19.6 1.9 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 EPX74971.1 - 0.0016 18.5 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Prolamin_like PF05617.6 EPX74971.1 - 0.041 14.0 0.1 0.08 13.0 0.1 1.5 1 0 0 1 1 1 0 Prolamin-like Sulfate_transp PF00916.15 EPX74972.1 - 3.6e-56 190.2 3.3 6e-56 189.5 2.3 1.3 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 EPX74972.1 - 6e-12 45.2 0.0 1.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EPX74972.1 - 2.3e-08 33.4 0.2 4.6e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 STAS domain DAHP_synth_1 PF00793.15 EPX74973.1 - 9.1e-104 345.9 0.1 1.1e-103 345.6 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family RhoGEF PF00621.15 EPX74974.1 - 9.2e-35 120.1 0.3 3.5e-34 118.2 0.0 2.0 2 1 0 2 2 2 1 RhoGEF domain Ribosomal_S4 PF00163.14 EPX74976.1 - 2.7e-28 98.1 0.9 4.4e-28 97.5 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EPX74976.1 - 6.5e-11 41.4 1.0 6.5e-11 41.4 0.7 2.4 3 0 0 3 3 3 1 S4 domain SLD3 PF08639.5 EPX74977.1 - 4.3e-34 118.0 25.6 4.3e-34 118.0 17.8 1.9 2 1 0 2 2 2 1 DNA replication regulator SLD3 Rhodanese PF00581.15 EPX74978.1 - 3.2e-14 53.2 0.0 8.1e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain SHIPPO-rpt PF07004.7 EPX74978.1 - 0.92 10.5 3.9 2.4 9.2 0.1 3.1 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat Neuro_bHLH PF12533.3 EPX74978.1 - 5.8 7.7 12.1 0.32 11.8 0.5 3.2 3 0 0 3 3 3 0 Neuronal helix-loop-helix transcription factor Hexokinase_2 PF03727.11 EPX74979.1 - 2.6e-94 314.9 0.0 3.4e-94 314.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EPX74979.1 - 8.6e-80 266.9 0.0 1.2e-79 266.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Cullin PF00888.17 EPX74980.1 - 6.2e-152 507.1 13.2 7.8e-152 506.8 9.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EPX74980.1 - 7e-29 99.4 1.6 3.4e-28 97.2 0.4 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain zf-DNL PF05180.7 EPX74981.1 - 1.1e-29 101.9 3.1 2.2e-29 100.9 2.2 1.5 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 EPX74981.1 - 0.01 15.4 2.3 0.01 15.4 1.6 1.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like HypA PF01155.14 EPX74981.1 - 0.042 13.5 0.6 0.071 12.7 0.4 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 EPX74981.1 - 0.076 12.7 1.1 4.2 7.1 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EPX74981.1 - 0.12 11.9 1.5 3.9 7.1 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain E7 PF00527.13 EPX74981.1 - 0.31 11.1 5.5 4.7 7.4 3.9 2.2 1 1 0 1 1 1 0 E7 protein, Early protein Zn_Tnp_IS1595 PF12760.2 EPX74981.1 - 0.65 9.8 6.1 1 9.2 0.5 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.1 EPX74981.1 - 1.7 8.7 6.0 3 7.9 0.2 2.5 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TFIIS_C PF01096.13 EPX74981.1 - 3.9 7.1 10.9 9.4 5.9 4.9 2.7 2 1 1 3 3 3 0 Transcription factor S-II (TFIIS) MBOAT PF03062.14 EPX74982.1 - 4.5e-47 160.7 29.7 4.5e-47 160.7 20.6 2.8 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Dopey_N PF04118.9 EPX74983.1 - 5.6e-98 327.5 0.1 3e-97 325.1 0.1 2.4 1 0 0 1 1 1 1 Dopey, N-terminal SLX9 PF15341.1 EPX74984.1 - 1.6e-21 76.9 12.8 1.6e-21 76.9 8.8 1.6 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Minor_capsid_1 PF10665.4 EPX74984.1 - 0.04 13.7 0.3 0.068 13.0 0.2 1.4 1 0 0 1 1 1 0 Minor capsid protein DUF4414 PF14377.1 EPX74984.1 - 0.2 11.5 4.9 0.33 10.9 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) Allexi_40kDa PF05549.6 EPX74984.1 - 0.32 10.2 3.0 0.4 9.9 2.1 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein YqzE PF14038.1 EPX74984.1 - 0.38 10.5 3.4 0.41 10.4 0.2 2.4 2 0 0 2 2 2 0 YqzE-like protein EXS PF03124.9 EPX74985.1 - 1.9e-67 227.7 27.2 2.2e-67 227.5 18.9 1.0 1 0 0 1 1 1 1 EXS family Anticodon_1 PF08264.8 EPX74985.1 - 0.0024 17.6 0.1 0.0042 16.8 0.1 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA PIG-Y PF15159.1 EPX74986.1 - 7.1e-05 22.9 6.6 9.3e-05 22.5 4.6 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y SieB PF14163.1 EPX74986.1 - 0.17 11.4 0.1 0.17 11.4 0.1 1.8 2 0 0 2 2 2 0 Superinfection exclusion protein B Adeno_E3B PF03376.9 EPX74986.1 - 0.48 10.3 5.4 0.15 11.9 0.5 2.0 2 0 0 2 2 2 0 Adenovirus E3B protein Tetraspannin PF00335.15 EPX74986.1 - 1.2 8.3 5.6 1.4 8.1 3.9 1.1 1 0 0 1 1 1 0 Tetraspanin family PepSY_TM PF03929.11 EPX74986.1 - 4.5 7.8 9.4 9 6.9 2.3 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix Rrp15p PF07890.7 EPX74987.1 - 3.1e-29 101.6 5.0 3.1e-29 101.6 3.4 1.8 2 0 0 2 2 2 1 Rrp15p Herpes_env PF01673.13 EPX74987.1 - 0.48 8.9 3.5 0.62 8.5 2.4 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Daxx PF03344.10 EPX74987.1 - 0.49 8.8 16.1 0.54 8.6 11.2 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EPX74987.1 - 3.6 5.4 14.4 4.8 5.1 10.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Mito_carr PF00153.22 EPX74988.1 - 4.7e-64 212.1 0.8 1.4e-22 79.2 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Autophagy_act_C PF03987.10 EPX74989.1 - 1.7e-08 34.5 0.0 3.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Prefoldin_2 PF01920.15 EPX74990.1 - 6.2e-20 70.9 6.3 7.1e-20 70.7 4.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.7 EPX74990.1 - 0.051 13.8 2.9 4.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FAM74 PF15026.1 EPX74990.1 - 0.088 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 FAM74 protein DUF3496 PF12001.3 EPX74990.1 - 0.09 13.0 1.1 0.13 12.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) Ead_Ea22 PF13935.1 EPX74990.1 - 0.13 12.6 2.3 0.16 12.2 1.6 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein Ax_dynein_light PF10211.4 EPX74990.1 - 0.27 11.0 5.0 0.18 11.6 1.5 1.8 2 0 0 2 2 2 0 Axonemal dynein light chain XhlA PF10779.4 EPX74990.1 - 0.3 11.0 3.9 0.39 10.6 0.4 2.1 2 0 0 2 2 2 0 Haemolysin XhlA DUF749 PF05370.6 EPX74990.1 - 0.44 10.5 2.5 1 9.3 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF749) Tropomyosin_1 PF12718.2 EPX74990.1 - 0.82 9.5 9.4 1.6 8.5 6.5 1.5 1 1 0 1 1 1 0 Tropomyosin like WD40 PF00400.27 EPX74991.1 - 8.4e-11 41.3 3.2 0.42 10.5 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Yip1 PF04893.12 EPX74992.1 - 7.9e-13 48.2 10.6 1.3e-12 47.5 7.3 1.4 1 1 0 1 1 1 1 Yip1 domain zf-CCCH PF00642.19 EPX74993.1 - 3.8e-16 58.3 19.9 2.3e-07 30.3 0.4 4.3 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPX74993.1 - 0.0098 15.8 0.9 0.0098 15.8 0.6 4.4 4 1 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type Viral_cys_rich PF08008.7 EPX74993.1 - 0.26 10.8 3.4 2.1 7.9 0.5 2.4 2 1 0 2 2 2 0 Viral cysteine rich LUC7 PF03194.10 EPX74993.1 - 4.2 6.8 5.0 12 5.3 0.1 2.4 2 1 1 3 3 3 0 LUC7 N_terminus Mur_ligase_M PF08245.7 EPX74994.1 - 8e-09 35.8 0.3 2.4e-08 34.2 0.2 1.8 1 1 0 1 1 1 1 Mur ligase middle domain PRKCSH PF07915.8 EPX74995.1 - 2.5e-06 28.1 0.1 1.2e-05 26.0 0.0 2.2 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein ATG27 PF09451.5 EPX74995.1 - 0.00087 18.5 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 GAF_3 PF13492.1 EPX74995.1 - 0.13 12.3 0.0 2.3 8.3 0.0 2.2 1 1 1 2 2 2 0 GAF domain Prefoldin_2 PF01920.15 EPX74996.1 - 5.7e-26 90.3 9.4 6.5e-26 90.1 6.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EPX74996.1 - 0.0098 15.5 5.2 1.4 8.6 3.6 2.1 1 1 0 1 1 1 1 Prefoldin subunit Mnd1 PF03962.10 EPX74996.1 - 0.025 14.2 2.9 0.038 13.6 2.0 1.3 1 1 0 1 1 1 0 Mnd1 family DASH_Dad3 PF08656.5 EPX74996.1 - 0.03 13.9 3.8 0.41 10.3 0.8 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF479 PF04336.7 EPX74996.1 - 0.039 14.0 2.7 0.32 11.1 1.3 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF479 TSC22 PF01166.13 EPX74996.1 - 0.043 13.7 1.2 3.3 7.7 0.0 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF2935 PF11155.3 EPX74996.1 - 0.056 13.5 0.9 0.086 12.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) DUF4618 PF15397.1 EPX74996.1 - 0.066 12.5 7.0 0.078 12.2 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) V_ATPase_I PF01496.14 EPX74996.1 - 0.08 10.7 2.3 0.1 10.4 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RVT_3 PF13456.1 EPX74996.1 - 0.12 12.1 0.4 0.64 9.8 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase-like Cortex-I_coil PF09304.5 EPX74996.1 - 0.13 12.3 5.8 0.3 11.1 3.3 1.8 1 1 0 1 1 1 0 Cortexillin I, coiled coil ATG_C PF09333.6 EPX74996.1 - 0.15 12.2 0.7 2.1 8.5 0.4 2.1 1 1 0 1 1 1 0 ATG C terminal domain Phage_GP20 PF06810.6 EPX74996.1 - 0.2 11.0 11.4 0.98 8.8 2.6 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 YtxH PF12732.2 EPX74996.1 - 0.22 11.9 1.8 1.4 9.3 0.0 2.0 2 0 0 2 2 2 0 YtxH-like protein BLOC1_2 PF10046.4 EPX74996.1 - 0.28 11.3 6.9 2.3 8.4 0.8 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YgaB PF14182.1 EPX74996.1 - 0.4 10.9 7.8 1 9.6 0.3 2.9 2 1 1 3 3 3 0 YgaB-like protein Tho2 PF11262.3 EPX74996.1 - 0.6 9.1 5.0 0.24 10.3 0.7 1.9 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TMF_DNA_bd PF12329.3 EPX74996.1 - 0.61 9.9 4.2 5.2 6.9 0.5 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 EPX74996.1 - 0.61 9.9 3.0 3.8 7.3 1.9 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2968 PF11180.3 EPX74996.1 - 1.1 8.6 8.6 3.4 7.0 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF972 PF06156.8 EPX74996.1 - 1.9 8.8 6.4 8.5 6.7 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EPX74996.1 - 2.4 7.7 8.1 7.8 6.0 5.6 1.7 1 1 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 EPX74996.1 - 2.4 7.8 9.0 12 5.6 6.1 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF904 PF06005.7 EPX74996.1 - 2.9 8.2 7.2 7.8 6.8 0.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF904) Spc24 PF08286.6 EPX74996.1 - 3.2 7.4 7.0 2.4 7.8 0.8 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4337 PF14235.1 EPX74996.1 - 3.5 7.4 5.5 12 5.6 3.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) PspA_IM30 PF04012.7 EPX74996.1 - 5.7 6.2 9.7 6.1 6.1 0.8 2.1 2 0 0 2 2 2 0 PspA/IM30 family WD40 PF00400.27 EPX74997.1 - 1.2e-56 186.6 16.5 1.5e-09 37.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EPX74997.1 - 1.6e-09 36.8 0.1 3.6e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EPX74997.1 - 2.8e-07 30.4 0.1 0.004 16.8 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPX74997.1 - 0.035 12.2 2.5 3.8 5.5 0.7 3.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF2066 PF09839.4 EPX74997.1 - 0.093 11.8 0.6 0.5 9.4 0.0 2.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2066) NifU_N PF01592.11 EPX74998.1 - 1e-51 174.1 0.5 1.5e-51 173.5 0.0 1.4 2 0 0 2 2 2 1 NifU-like N terminal domain DUF240 PF03086.9 EPX74998.1 - 0.097 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 MG032/MG096/MG288 family 2 AAA_17 PF13207.1 EPX74999.1 - 3.3e-06 27.9 0.0 8.3e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPX74999.1 - 3.4e-06 26.2 0.0 1.5e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin PRK PF00485.13 EPX74999.1 - 1.1e-05 25.0 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EPX74999.1 - 7.3e-05 23.0 0.0 0.00012 22.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EPX74999.1 - 0.00018 21.1 0.1 0.00039 20.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EPX74999.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EPX74999.1 - 0.0013 18.5 0.1 0.004 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPX74999.1 - 0.0016 18.1 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain KAP_NTPase PF07693.9 EPX74999.1 - 0.0032 16.4 0.0 0.0035 16.3 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain ArgK PF03308.11 EPX74999.1 - 0.0057 15.4 0.0 0.0082 14.9 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA PF00004.24 EPX74999.1 - 0.0058 16.8 0.0 0.0096 16.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EPX74999.1 - 0.0062 15.4 0.0 0.016 14.0 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.1 EPX74999.1 - 0.0068 16.3 0.2 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EPX74999.1 - 0.0073 15.2 0.0 0.02 13.7 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 EPX74999.1 - 0.0091 15.4 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EPX74999.1 - 0.013 14.4 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 EPX74999.1 - 0.019 15.2 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.17 EPX74999.1 - 0.037 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EPX74999.1 - 0.041 13.4 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EPX74999.1 - 0.06 12.5 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CoaE PF01121.15 EPX74999.1 - 0.066 12.6 0.8 0.09 12.1 0.1 1.5 2 0 0 2 2 2 0 Dephospho-CoA kinase cobW PF02492.14 EPX74999.1 - 0.067 12.6 0.2 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EPX74999.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.17 EPX74999.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 EPX74999.1 - 0.076 12.4 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EPX74999.1 - 0.081 13.0 0.3 0.28 11.3 0.1 1.9 1 1 1 2 2 2 0 AAA domain Miro PF08477.8 EPX74999.1 - 0.082 13.4 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 EPX74999.1 - 0.097 12.0 0.1 0.9 8.9 0.1 1.9 1 1 0 2 2 2 0 AAA-like domain Sigma54_activ_2 PF14532.1 EPX74999.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF1752 PF08550.5 EPX75000.1 - 2e-07 30.4 4.5 3.7e-07 29.5 3.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Sld5 PF05916.6 EPX75001.1 - 1.5e-12 47.7 0.0 1.9e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Ribosomal_L7Ae PF01248.21 EPX75002.1 - 1.5e-24 85.3 1.0 2.5e-24 84.6 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-HIT PF04438.11 EPX75003.1 - 3.7e-07 29.6 12.6 8e-07 28.6 8.7 1.6 1 0 0 1 1 1 1 HIT zinc finger Ribosomal_S15 PF00312.17 EPX75003.1 - 0.14 11.9 0.8 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S15 PolC_DP2 PF03833.8 EPX75003.1 - 2.3 5.7 5.4 2.6 5.5 3.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.13 EPX75003.1 - 4.1 7.3 14.8 9 6.2 10.2 1.7 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.19 EPX75003.1 - 7.5 6.5 13.1 10 6.0 0.1 2.3 2 0 0 2 2 2 0 B-box zinc finger WD40 PF00400.27 EPX75004.1 - 1.4e-17 62.8 1.2 9.1e-07 28.5 0.0 5.2 4 1 0 4 4 4 4 WD domain, G-beta repeat PQQ PF01011.16 EPX75004.1 - 0.01 15.3 0.0 0.37 10.4 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_2 PF13360.1 EPX75004.1 - 0.018 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain DUF1859 PF08948.5 EPX75004.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1859) RRM_1 PF00076.17 EPX75005.1 - 1.4e-15 56.6 0.0 2.1e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX75005.1 - 1.6e-10 40.7 0.0 2.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX75005.1 - 4.6e-09 35.9 0.0 7.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S51 PF03575.12 EPX75005.1 - 0.037 13.7 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 DUF3791 PF12668.2 EPX75005.1 - 0.13 11.9 0.1 8.9 6.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3791) Elongin_A PF06881.6 EPX75006.1 - 1e-25 90.2 1.8 1.6e-25 89.6 1.2 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ABC_tran PF00005.22 EPX75007.1 - 6.5e-46 156.0 4.6 1.7e-22 80.2 0.0 3.3 4 0 0 4 4 3 2 ABC transporter ABC_tran_2 PF12848.2 EPX75007.1 - 3.3e-22 78.1 8.0 3.3e-22 78.1 5.5 2.8 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EPX75007.1 - 3.2e-15 56.8 11.0 0.00012 22.1 0.0 5.2 2 2 2 4 4 4 3 AAA domain SMC_N PF02463.14 EPX75007.1 - 3.8e-10 39.3 0.7 0.11 11.6 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EPX75007.1 - 2.2e-09 38.1 1.9 0.0045 17.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EPX75007.1 - 3.3e-08 32.9 0.1 0.0077 15.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EPX75007.1 - 1.3e-07 31.7 0.6 0.017 15.1 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EPX75007.1 - 2.9e-07 30.6 0.0 0.012 15.8 0.0 3.3 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EPX75007.1 - 4.6e-07 29.8 0.0 0.0085 16.0 0.0 3.2 2 1 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EPX75007.1 - 7.4e-06 26.4 0.0 0.21 12.1 0.0 3.0 2 1 0 2 2 2 2 Miro-like protein MobB PF03205.9 EPX75007.1 - 8.8e-06 25.4 0.8 0.047 13.3 0.0 3.5 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EPX75007.1 - 1.1e-05 25.7 6.3 0.14 12.5 0.0 4.5 5 1 0 5 5 5 2 AAA domain ArgK PF03308.11 EPX75007.1 - 1.1e-05 24.3 0.3 0.11 11.2 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_14 PF13173.1 EPX75007.1 - 1.4e-05 25.0 0.3 0.33 10.8 0.0 3.7 3 1 1 4 4 3 2 AAA domain SbcCD_C PF13558.1 EPX75007.1 - 3.2e-05 23.7 0.3 0.042 13.7 0.1 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EPX75007.1 - 3.7e-05 23.3 0.0 0.037 13.6 0.0 3.8 4 2 0 4 4 3 1 AAA domain AAA PF00004.24 EPX75007.1 - 4.2e-05 23.7 0.0 0.052 13.7 0.0 3.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EPX75007.1 - 5.2e-05 22.4 0.1 0.37 9.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NACHT PF05729.7 EPX75007.1 - 7.8e-05 22.3 0.0 0.2 11.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain NTPase_1 PF03266.10 EPX75007.1 - 8.6e-05 22.3 0.0 0.84 9.3 0.0 3.0 3 0 0 3 3 3 2 NTPase AAA_10 PF12846.2 EPX75007.1 - 0.00012 21.6 0.0 0.25 10.7 0.1 3.4 3 0 0 3 3 3 1 AAA-like domain RNA_helicase PF00910.17 EPX75007.1 - 0.00024 21.2 0.0 0.16 12.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EPX75007.1 - 0.00041 20.3 0.5 0.28 11.1 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EPX75007.1 - 0.001 18.9 0.0 0.42 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPX75007.1 - 0.0012 18.3 0.5 1.2 8.4 0.0 2.9 2 2 0 2 2 2 2 AAA domain KAP_NTPase PF07693.9 EPX75007.1 - 0.0017 17.4 0.0 0.11 11.4 0.0 3.0 4 0 0 4 4 4 1 KAP family P-loop domain AAA_23 PF13476.1 EPX75007.1 - 0.0027 18.0 23.0 0.052 13.8 0.0 5.0 5 0 0 5 5 5 2 AAA domain cobW PF02492.14 EPX75007.1 - 0.0056 16.1 0.7 1.4 8.3 0.0 3.0 4 0 0 4 4 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EPX75007.1 - 0.0056 16.5 7.0 1.3 8.7 0.0 4.1 4 1 0 4 4 4 2 Dynamin family T2SE PF00437.15 EPX75007.1 - 0.0074 15.2 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_5 PF07728.9 EPX75007.1 - 0.01 15.5 0.1 8.8 6.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EPX75007.1 - 0.012 15.0 3.8 0.34 10.3 0.0 3.8 4 0 0 4 4 4 0 FtsK/SpoIIIE family GBP_repeat PF02526.9 EPX75007.1 - 0.014 14.7 0.3 0.15 11.5 0.0 2.3 2 0 0 2 2 2 0 Glycophorin-binding protein DUF87 PF01935.12 EPX75007.1 - 0.019 14.7 0.0 0.019 14.7 0.0 4.7 4 1 1 5 5 5 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 EPX75007.1 - 0.037 13.5 0.0 1.9 7.9 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 EPX75007.1 - 0.038 13.0 19.3 1.2 8.0 0.0 5.5 4 1 2 6 6 5 0 AAA ATPase domain PMC2NT PF08066.7 EPX75007.1 - 0.047 13.9 4.0 0.06 13.6 0.5 2.6 2 0 0 2 2 2 0 PMC2NT (NUC016) domain ATP_bind_1 PF03029.12 EPX75007.1 - 0.057 12.9 0.0 1.4 8.4 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MutS_V PF00488.16 EPX75007.1 - 0.13 11.6 0.1 7.7 5.8 0.0 2.5 2 0 0 2 2 2 0 MutS domain V Arch_ATPase PF01637.13 EPX75007.1 - 0.25 10.9 9.6 1.1 8.9 0.0 4.0 4 0 0 4 4 4 0 Archaeal ATPase DUF2513 PF10711.4 EPX75007.1 - 0.44 10.6 8.1 0.67 10.0 0.5 3.2 3 0 0 3 3 3 0 Hypothetical protein (DUF2513) ATP_sub_h PF10775.4 EPX75008.1 - 2.9e-15 55.7 0.8 4.3e-15 55.1 0.6 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h Mito_carr PF00153.22 EPX75009.1 - 3.3e-43 145.3 0.1 3.2e-18 65.2 0.0 3.9 2 2 1 3 3 3 3 Mitochondrial carrier protein PWWP PF00855.12 EPX75010.1 - 3.6e-13 49.5 3.8 1.5e-10 41.0 0.1 3.0 3 0 0 3 3 3 2 PWWP domain Med26 PF08711.6 EPX75010.1 - 0.008 15.6 0.8 0.041 13.4 0.1 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Ribosomal_S4 PF00163.14 EPX75011.1 - 2.7e-28 98.1 0.9 4.4e-28 97.5 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EPX75011.1 - 6.5e-11 41.4 1.0 6.5e-11 41.4 0.7 2.4 3 0 0 3 3 3 1 S4 domain Telomerase_RBD PF12009.3 EPX75012.1 - 1.8e-36 125.0 9.5 1.8e-36 125.0 6.6 2.9 3 0 0 3 3 3 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EPX75012.1 - 1.3e-08 34.4 3.7 9.9e-08 31.5 2.6 2.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DAP3 PF10236.4 EPX75013.1 - 2.7e-61 207.2 0.0 3.4e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 FB_lectin PF07367.6 EPX75013.1 - 0.051 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Fungal fruit body lectin RRS1 PF04939.7 EPX75014.1 - 2.2e-53 180.1 4.1 2.4e-53 179.9 2.8 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Baculo_LEF-3 PF05847.6 EPX75014.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) RhoGEF PF00621.15 EPX75015.1 - 6.2e-27 94.6 6.7 5.9e-26 91.4 1.2 2.3 2 0 0 2 2 2 2 RhoGEF domain Cytochrom_C1 PF02167.10 EPX75016.1 - 1e-83 280.3 0.0 1.5e-83 279.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EPX75016.1 - 0.0026 17.8 0.0 0.008 16.3 0.0 1.9 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EPX75016.1 - 0.1 13.4 0.0 1.3 9.9 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c Lactonase PF10282.4 EPX75017.1 - 3.2e-67 227.0 0.0 3.6e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NHL PF01436.16 EPX75017.1 - 0.0015 18.3 0.4 0.68 10.0 0.0 3.4 3 0 0 3 3 3 1 NHL repeat Arylesterase PF01731.15 EPX75017.1 - 0.0079 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Arylesterase DUF1513 PF07433.6 EPX75017.1 - 0.018 13.9 0.0 0.11 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Aminotran_1_2 PF00155.16 EPX75018.1 - 3e-37 128.4 0.1 4.8e-37 127.7 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EPX75018.1 - 0.00021 19.7 0.0 0.00035 18.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CENP-K PF11802.3 EPX75019.1 - 1.9e-26 92.9 9.6 2.5e-26 92.5 6.6 1.2 1 0 0 1 1 1 1 Centromere-associated protein K OmpA_membrane PF01389.12 EPX75019.1 - 0.038 13.5 0.1 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 OmpA-like transmembrane domain POP1 PF06978.6 EPX75019.1 - 0.045 13.4 1.5 0.063 12.9 1.1 1.4 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 AcylCoA_dehyd_C PF12186.3 EPX75019.1 - 0.07 12.9 1.5 0.16 11.8 0.1 2.2 2 1 1 3 3 3 0 Acyl-CoA dehydrogenase C terminal Guanylin PF02058.10 EPX75019.1 - 3.4 7.8 6.3 7.6 6.6 0.1 3.6 3 1 1 4 4 4 0 Guanylin precursor DUF3810 PF12725.2 EPX75020.1 - 0.099 11.5 0.1 0.099 11.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF3007 PF11460.3 EPX75020.1 - 0.11 12.6 1.1 0.18 11.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) ABC2_membrane_3 PF12698.2 EPX75020.1 - 1.4 7.8 12.7 2.6 6.9 8.8 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Elong_Iki1 PF10483.4 EPX75021.1 - 1.8e-65 221.0 0.0 2.2e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 AAA_35 PF14516.1 EPX75021.1 - 0.092 11.3 0.1 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain Ribosomal_L16 PF00252.13 EPX75022.1 - 1.8e-32 111.9 0.2 2.3e-32 111.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_S21e PF01249.13 EPX75023.1 - 1.4e-40 137.1 0.0 1.5e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF3210 PF11489.3 EPX75024.1 - 2.8e-20 72.6 84.5 9.5e-16 57.6 58.6 3.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3210) MIP-T3 PF10243.4 EPX75024.1 - 0.11 10.9 53.2 0.18 10.2 36.8 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mitofilin PF09731.4 EPX75024.1 - 8.6 4.8 31.6 14 4.1 21.9 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Acetyltransf_3 PF13302.1 EPX75025.1 - 3e-18 66.3 0.0 3.4e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPX75025.1 - 1.1e-10 41.3 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EPX75025.1 - 5.2e-06 26.4 0.0 1.7e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPX75025.1 - 1e-05 25.5 0.0 2.6e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPX75025.1 - 0.019 15.1 0.0 0.05 13.7 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_51K PF01512.12 EPX75026.1 - 4.2e-28 97.9 0.0 6.7e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit SLBB PF10531.4 EPX75026.1 - 1.2e-07 31.4 0.1 2.4e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 SLBB domain NADH_4Fe-4S PF10589.4 EPX75026.1 - 9.4e-05 21.4 0.0 0.00024 20.1 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region YjeF_N PF03853.10 EPX75027.1 - 1.2e-23 83.5 0.1 2.1e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EPX75027.1 - 3.9e-08 33.7 16.4 3.9e-08 33.7 11.4 2.8 2 1 1 3 3 3 1 FDF domain Peptidase_M16_C PF05193.16 EPX75028.1 - 5.1e-37 127.3 0.0 8e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EPX75028.1 - 4.7e-34 117.2 0.1 1.3e-33 115.8 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AAA_5 PF07728.9 EPX75028.1 - 0.044 13.5 0.0 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IF3_C PF00707.17 EPX75029.1 - 9.2e-09 34.9 0.0 1.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EPX75029.1 - 0.00046 19.6 4.6 0.00066 19.0 3.2 1.2 1 0 0 1 1 1 1 Mitochondrial translation initiation factor Ctr PF04145.10 EPX75030.1 - 1.4e-27 96.5 10.1 1.1e-26 93.6 7.0 1.9 1 1 0 1 1 1 1 Ctr copper transporter family Cytochrom_B_N PF00033.14 EPX75030.1 - 0.0075 15.6 1.1 0.017 14.5 0.8 1.6 1 1 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 EPX75030.1 - 0.021 14.1 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Abi PF02517.11 EPX75030.1 - 0.033 14.3 4.4 2.5 8.2 0.3 2.1 2 0 0 2 2 2 0 CAAX protease self-immunity EPV_E5 PF08135.6 EPX75030.1 - 6.2 6.8 6.2 5.3 7.1 0.2 2.2 2 0 0 2 2 2 0 Major transforming protein E5 family Sel1 PF08238.7 EPX75031.1 - 0.0043 17.6 0.3 5.9 7.6 0.0 3.0 3 0 0 3 3 3 2 Sel1 repeat BNIP3 PF06553.7 EPX75031.1 - 1.1 8.5 9.0 0.027 13.8 1.6 1.7 2 0 0 2 2 2 0 BNIP3 SUI1 PF01253.17 EPX75032.1 - 1.2e-29 101.9 1.2 1.5e-29 101.6 0.9 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Yqai PF09466.5 EPX75032.1 - 0.046 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Hypothetical protein Yqai DUF2404 PF10296.4 EPX75033.1 - 1.4e-24 86.0 0.0 3.3e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) CMS1 PF14617.1 EPX75034.1 - 2.1e-73 246.5 5.6 2.6e-73 246.2 3.9 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EPX75034.1 - 4.1e-06 26.4 1.6 3.7e-05 23.2 0.0 2.1 1 1 0 2 2 2 1 DEAD/DEAH box helicase DUF4614 PF15391.1 EPX75034.1 - 0.55 9.9 7.6 0.89 9.2 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) YqfQ PF14181.1 EPX75034.1 - 8.5 6.3 10.4 22 5.0 7.3 1.5 2 0 0 2 2 2 0 YqfQ-like protein RhoGAP PF00620.22 EPX75035.1 - 2.3e-44 150.6 0.2 1.4e-43 148.0 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EPX75035.1 - 1.2e-07 31.7 5.4 5.6e-07 29.6 3.8 2.3 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SBP PF03110.9 EPX75035.1 - 0.11 12.7 1.2 0.18 12.0 0.1 1.9 2 0 0 2 2 2 0 SBP domain HMG_box PF00505.14 EPX75036.1 - 0.0032 17.6 0.5 0.029 14.6 0.0 2.5 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPX75036.1 - 0.044 14.1 0.0 0.069 13.5 0.0 1.4 1 1 0 1 1 1 0 HMG-box domain Homeobox_KN PF05920.6 EPX75037.1 - 8.7e-14 50.9 0.7 1.7e-13 50.0 0.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EPX75037.1 - 1.9e-06 27.3 0.0 3.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EPX75037.1 - 0.0094 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HhH-GPD PF00730.20 EPX75038.1 - 5e-07 29.9 0.0 8.9e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein AAA PF00004.24 EPX75039.1 - 4.9e-44 149.7 0.0 9.9e-44 148.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EPX75039.1 - 2.8e-08 33.8 0.0 5.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EPX75039.1 - 1.4e-06 28.0 0.0 9.2e-06 25.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPX75039.1 - 3.9e-06 26.9 0.1 2e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPX75039.1 - 4e-06 27.0 0.1 0.00024 21.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPX75039.1 - 5.5e-05 23.9 0.0 0.00015 22.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPX75039.1 - 0.00019 20.5 0.0 0.00039 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EPX75039.1 - 0.00033 20.3 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EPX75039.1 - 0.0006 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein cobW PF02492.14 EPX75039.1 - 0.0009 18.7 0.5 0.18 11.2 0.1 2.6 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EPX75039.1 - 0.0011 18.9 0.0 0.0038 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EPX75039.1 - 0.0011 17.7 0.1 0.0026 16.5 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus KaiC PF06745.8 EPX75039.1 - 0.0013 17.9 0.0 0.0034 16.5 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.1 EPX75039.1 - 0.002 17.9 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPX75039.1 - 0.0023 18.2 0.2 0.0091 16.3 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EPX75039.1 - 0.0028 17.6 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPX75039.1 - 0.005 15.9 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EPX75039.1 - 0.0057 16.2 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EPX75039.1 - 0.0078 15.4 0.2 0.022 13.9 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EPX75039.1 - 0.016 14.4 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 EPX75039.1 - 0.022 14.1 0.0 0.12 11.7 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EPX75039.1 - 0.027 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EPX75039.1 - 0.031 13.7 0.0 0.18 11.2 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EPX75039.1 - 0.031 14.4 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EPX75039.1 - 0.039 13.5 0.0 0.74 9.4 0.0 2.2 1 1 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 EPX75039.1 - 0.05 12.4 0.0 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EPX75039.1 - 0.064 12.1 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2072 PF09845.4 EPX75039.1 - 0.084 12.7 0.6 0.19 11.6 0.4 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NB-ARC PF00931.17 EPX75039.1 - 0.1 11.4 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 EPX75039.1 - 0.11 12.6 0.0 0.37 10.9 0.0 1.9 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 SSF PF00474.12 EPX75040.1 - 2.8e-22 78.9 23.2 2.8e-22 78.9 16.1 1.6 1 1 0 1 1 1 1 Sodium:solute symporter family Mod_r PF07200.8 EPX75041.1 - 4.7e-05 23.3 7.6 5.9e-05 23.0 5.3 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Atg14 PF10186.4 EPX75041.1 - 0.0012 17.8 5.2 0.0017 17.3 3.6 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 EPX75041.1 - 0.008 15.9 5.2 0.008 15.9 3.6 2.0 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein CCDC155 PF14662.1 EPX75041.1 - 0.031 13.8 8.6 0.039 13.5 5.9 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Fez1 PF06818.10 EPX75041.1 - 0.049 13.6 6.0 0.067 13.2 4.2 1.2 1 0 0 1 1 1 0 Fez1 OmpH PF03938.9 EPX75041.1 - 0.3 10.9 5.8 0.41 10.5 4.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.10 EPX75041.1 - 5.3 6.1 8.9 16 4.5 6.1 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Ribosomal_60s PF00428.14 EPX75042.1 - 6.1e-26 90.6 11.4 7e-26 90.4 7.9 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF1308 PF07000.6 EPX75042.1 - 0.047 12.3 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) TT_ORF2 PF02957.10 EPX75042.1 - 0.14 12.8 0.6 0.23 12.1 0.4 1.3 1 1 0 1 1 1 0 TT viral ORF2 TOH_N PF12549.3 EPX75042.1 - 0.23 11.0 1.8 0.58 9.7 1.2 1.7 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal HMG_box PF00505.14 EPX75043.1 - 0.0032 17.6 0.5 0.029 14.6 0.0 2.5 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPX75043.1 - 0.044 14.1 0.0 0.069 13.5 0.0 1.4 1 1 0 1 1 1 0 HMG-box domain Homeobox_KN PF05920.6 EPX75044.1 - 8.7e-14 50.9 0.7 1.7e-13 50.0 0.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EPX75044.1 - 1.9e-06 27.3 0.0 3.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EPX75044.1 - 0.0094 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HMG_box PF00505.14 EPX75045.1 - 2.6e-21 75.6 1.3 3.9e-21 75.0 0.9 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPX75045.1 - 2.7e-06 27.6 0.5 4.2e-06 27.0 0.4 1.4 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EPX75045.1 - 0.028 13.7 0.2 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 Hydrolase_3 PF08282.7 EPX75046.1 - 8.4e-48 163.1 0.0 9.6e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EPX75046.1 - 5.2e-11 42.3 0.0 2.7e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Orn_Arg_deC_N PF02784.11 EPX75046.1 - 5.2e-05 22.5 0.0 9.5e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain HAD PF12710.2 EPX75046.1 - 0.00065 19.9 0.0 0.075 13.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPX75046.1 - 0.00085 19.7 0.0 0.0052 17.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EPX75046.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF1041 PF06292.12 EPX75046.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) Methyltransf_23 PF13489.1 EPX75047.1 - 2.5e-22 79.3 0.1 3.5e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX75047.1 - 4.6e-15 55.9 0.0 1.1e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX75047.1 - 1.9e-14 53.5 0.0 2.8e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX75047.1 - 1.6e-13 50.9 0.0 4.2e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX75047.1 - 6.1e-12 46.1 0.0 1.1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPX75047.1 - 3.2e-09 36.8 0.0 6.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX75047.1 - 7.1e-08 32.7 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPX75047.1 - 3e-05 23.4 0.0 4.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EPX75047.1 - 3.6e-05 23.0 0.0 0.00059 19.0 0.0 2.5 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 EPX75047.1 - 7.9e-05 21.6 0.0 0.00013 20.9 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 EPX75047.1 - 0.0036 16.3 0.0 0.0063 15.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 EPX75047.1 - 0.0068 15.8 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EPX75047.1 - 0.024 14.3 0.0 0.067 12.8 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain TPMT PF05724.6 EPX75047.1 - 0.044 13.2 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FAD_binding_8 PF08022.7 EPX75048.1 - 5.5e-28 96.9 0.0 1.7e-27 95.3 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EPX75048.1 - 1.5e-17 63.9 0.0 1.5e-16 60.7 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPX75048.1 - 5.2e-13 49.1 12.7 5.2e-13 49.1 8.8 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EPX75048.1 - 8.4e-05 23.1 0.0 0.00027 21.4 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain VIT1 PF01988.14 EPX75050.1 - 3.5e-59 199.8 11.2 4e-59 199.6 7.8 1.0 1 0 0 1 1 1 1 VIT family Perilipin PF03036.11 EPX75050.1 - 0.021 13.6 0.2 0.039 12.7 0.1 1.5 1 1 0 1 1 1 0 Perilipin family Claudin_2 PF13903.1 EPX75050.1 - 0.12 12.0 5.3 1.3 8.6 0.2 2.2 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 EPX75050.1 - 3.5 6.8 6.8 4.3 6.5 4.0 1.6 2 0 0 2 2 2 0 Tetraspanin family AAA_26 PF13500.1 EPX75051.1 - 1.2e-52 178.4 0.1 1.4e-52 178.2 0.1 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EPX75051.1 - 9e-06 25.2 0.5 3e-05 23.5 0.3 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Aminotran_3 PF00202.16 EPX75052.1 - 8.1e-92 307.6 0.0 9.5e-92 307.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EPX75052.1 - 8.2e-05 21.7 0.0 0.00023 20.2 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II ADH_N PF08240.7 EPX75053.1 - 1.5e-23 82.6 3.0 1.5e-23 82.6 2.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPX75053.1 - 2.8e-11 43.0 0.0 1.4e-08 34.3 0.0 2.4 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EPX75053.1 - 7.6e-08 31.8 0.4 2.8e-07 30.0 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Methyltransf_18 PF12847.2 EPX75053.1 - 0.028 15.0 0.0 0.093 13.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EPX75053.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4646 PF15496.1 EPX75054.1 - 8.5e-32 109.8 0.0 1.8e-31 108.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) Erf4 PF10256.4 EPX75054.1 - 4.2e-05 23.3 0.0 9.1e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family NuiA PF07924.6 EPX75054.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein DUF624 PF04854.9 EPX75054.1 - 0.14 11.9 0.1 0.45 10.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF624 Fungal_trans PF04082.13 EPX75055.1 - 3e-33 114.7 6.6 3e-33 114.7 4.6 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPX75055.1 - 1.8e-07 31.0 15.8 8.9e-05 22.6 3.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPX75055.1 - 3.6e-07 30.0 14.8 2.3e-05 24.4 2.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPX75055.1 - 7.2e-05 22.8 10.9 0.00023 21.3 3.7 3.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-Di19 PF05605.7 EPX75055.1 - 0.005 16.9 0.8 0.016 15.3 0.6 1.9 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF2024 PF09630.5 EPX75055.1 - 0.025 14.2 2.4 0.084 12.5 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) Guanylate_kin PF00625.16 EPX75056.1 - 1.4e-58 197.3 0.0 1.6e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 EPX75056.1 - 5.8e-06 26.4 0.1 1.5e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EPX75056.1 - 8.6e-06 26.5 0.1 1.7e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPX75056.1 - 1.8e-05 24.6 0.6 0.00012 21.8 0.4 2.0 1 1 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EPX75056.1 - 1.8e-05 24.9 0.2 0.00037 20.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPX75056.1 - 3.7e-05 24.0 0.1 0.00011 22.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPX75056.1 - 7.3e-05 22.0 0.2 9.7e-05 21.6 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EPX75056.1 - 9.2e-05 22.3 0.7 0.0014 18.4 0.5 2.3 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EPX75056.1 - 0.00032 20.6 0.0 0.00044 20.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPX75056.1 - 0.00046 20.6 0.0 0.00089 19.7 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EPX75056.1 - 0.00078 19.7 0.0 0.00099 19.4 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.1 EPX75056.1 - 0.00096 18.7 0.1 0.0023 17.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPX75056.1 - 0.0033 17.5 0.0 0.0053 16.9 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_10 PF12846.2 EPX75056.1 - 0.0044 16.5 0.2 0.0082 15.6 0.2 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 EPX75056.1 - 0.0069 15.9 0.1 0.017 14.6 0.0 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain PTS_IIB PF02302.12 EPX75056.1 - 0.0072 16.7 0.0 7.7 7.0 0.0 2.8 2 1 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit NACHT PF05729.7 EPX75056.1 - 0.0098 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 EPX75056.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPX75056.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EPX75056.1 - 0.02 14.8 0.0 0.046 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EPX75056.1 - 0.027 14.1 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EPX75056.1 - 0.034 14.4 1.4 0.11 12.8 1.0 1.7 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EPX75056.1 - 0.036 13.7 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 NTPase Rad17 PF03215.10 EPX75056.1 - 0.058 12.0 0.0 0.075 11.6 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Dynamin_N PF00350.18 EPX75056.1 - 0.075 12.8 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Dynamin family Tsp45I PF06300.7 EPX75056.1 - 0.082 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Tsp45I type II restriction enzyme S_100 PF01023.14 EPX75056.1 - 0.086 12.1 0.0 4.2 6.7 0.0 2.8 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain AAA_25 PF13481.1 EPX75056.1 - 0.092 12.1 0.1 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 EPX75056.1 - 0.14 11.8 0.3 0.36 10.4 0.0 1.8 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_19 PF13245.1 EPX75056.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Glyco_hydro_76 PF03663.9 EPX75057.1 - 4.3e-102 342.2 20.6 5.7e-102 341.8 14.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.9 EPX75058.1 - 9.6e-119 397.0 27.1 1.2e-118 396.7 18.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TFIIF_beta PF02270.10 EPX75059.1 - 8.8e-80 268.4 0.1 3.6e-53 181.1 0.0 2.2 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit WD40 PF00400.27 EPX75060.1 - 1.1e-24 85.3 9.7 9.6e-07 28.4 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EPX75060.1 - 4.4e-07 29.8 0.1 0.0073 16.0 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Sec23_trunk PF04811.10 EPX75061.1 - 1.4e-13 50.7 0.2 8e-12 45.0 0.1 2.4 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EPX75061.1 - 3.3e-08 33.9 0.2 7.5e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 EPX75061.1 - 1.6e-07 30.7 0.0 3.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EPX75061.1 - 2.3e-06 27.0 3.4 5.7e-06 25.7 1.8 2.2 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Myb_DNA-binding PF00249.26 EPX75062.1 - 1.3e-23 82.7 7.5 1.2e-10 41.2 0.1 4.0 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPX75062.1 - 3.5e-16 59.0 10.8 6.6e-12 45.3 0.8 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain tRNA-synt_2 PF00152.15 EPX75063.1 - 1.4e-63 214.7 0.0 1.1e-62 211.7 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPX75063.1 - 3.4e-09 36.4 0.0 6.6e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EPX75063.1 - 0.028 13.6 0.0 7.1 5.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Peptidase_M20 PF01546.23 EPX75064.1 - 1.2e-28 99.9 0.0 1.7e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPX75064.1 - 1.6e-16 60.0 0.0 6.9e-16 57.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Pirin PF02678.11 EPX75065.1 - 2.1e-25 88.6 0.2 3.7e-25 87.8 0.1 1.4 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EPX75065.1 - 9.1e-08 31.4 1.8 3.1e-07 29.7 0.5 2.1 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 EPX75065.1 - 0.024 14.3 0.4 0.082 12.5 0.1 1.9 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_3 PF05899.7 EPX75065.1 - 0.057 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) RasGAP PF00616.14 EPX75066.1 - 0.12 12.0 0.4 0.18 11.4 0.1 1.5 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Halogen_Hydrol PF10112.4 EPX75066.1 - 5.6 6.3 8.7 0.63 9.4 0.4 2.4 2 1 1 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein 6PGD PF00393.14 EPX75067.1 - 1e-130 435.1 0.0 1.3e-130 434.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EPX75067.1 - 3e-51 173.4 0.0 4.5e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Apolipo_F PF15148.1 EPX75068.1 - 0.049 12.9 3.3 0.053 12.8 1.9 1.4 1 1 0 1 1 1 0 Apolipoprotein F RRM_1 PF00076.17 EPX75069.1 - 1.8e-38 129.9 0.2 9.6e-18 63.5 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX75069.1 - 3.6e-31 106.9 0.1 7e-15 54.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX75069.1 - 2.9e-12 46.2 0.0 7.7e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPX75069.1 - 0.0044 16.7 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 EPX75070.1 - 1.2e-48 165.5 0.0 1.7e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX75070.1 - 2.5e-29 102.1 0.0 4e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX75070.1 - 0.0059 15.5 0.4 0.06 12.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPX75070.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rep_fac-A_C PF08646.5 EPX75071.1 - 7.4e-52 174.9 5.6 4.8e-50 169.0 2.1 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EPX75071.1 - 4.1e-30 103.5 0.2 8.5e-30 102.5 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EPX75071.1 - 1e-16 60.5 0.8 6.6e-14 51.5 0.0 3.4 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 EPX75071.1 - 9.7e-05 22.3 0.2 0.00037 20.5 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function DUF223 IBR PF01485.16 EPX75071.1 - 0.21 11.4 4.5 0.23 11.3 0.4 2.2 2 0 0 2 2 2 0 IBR domain Aminotran_5 PF00266.14 EPX75072.1 - 2.9e-25 88.7 0.0 3.8e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EPX75072.1 - 4.4e-05 22.5 0.0 6.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EPX75072.1 - 5.7e-05 21.5 0.0 7.8e-05 21.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SLA_LP_auto_ag PF05889.8 EPX75072.1 - 0.001 17.5 0.0 0.0018 16.7 0.0 1.4 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Pyridoxal_deC PF00282.14 EPX75072.1 - 0.014 13.8 0.0 0.022 13.2 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain RRM_1 PF00076.17 EPX75073.1 - 1.8e-30 104.3 0.1 2.1e-15 56.0 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX75073.1 - 4.8e-22 77.7 0.1 2.4e-11 43.4 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX75073.1 - 3.4e-14 52.4 0.0 4.4e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-3c_N PF05470.7 EPX75073.1 - 0.023 12.7 6.6 0.042 11.9 4.6 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4264 PF14084.1 EPX75073.1 - 0.029 13.7 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) DUF3213 PF11491.3 EPX75073.1 - 0.16 11.8 1.3 8.5 6.3 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3213) DUF3818 PF12825.2 EPX75073.1 - 1.1 7.9 4.0 0.57 8.8 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) CENP-T PF15511.1 EPX75073.1 - 7.7 5.6 24.6 0.074 12.2 7.1 2.2 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T GTP_EFTU PF00009.22 EPX75074.1 - 3.6e-57 192.8 0.0 5.8e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EPX75074.1 - 9e-23 79.9 0.0 2e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EPX75074.1 - 1.8e-12 46.9 0.1 9.1e-06 25.4 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPX75074.1 - 5.8e-10 39.1 0.2 1.1e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPX75074.1 - 0.0011 18.8 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EPX75074.1 - 0.036 13.1 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 EPX75074.1 - 0.043 14.3 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Streptin-Immun PF11083.3 EPX75076.1 - 1.3 9.0 5.0 0.33 10.9 0.4 2.3 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein MerR-DNA-bind PF09278.6 EPX75076.1 - 1.6 9.1 6.2 17 5.8 0.2 3.3 3 0 0 3 3 3 0 MerR, DNA binding Phasin PF05597.6 EPX75076.1 - 1.8 8.3 10.6 0.17 11.6 0.3 3.2 3 1 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Trehalase PF01204.13 EPX75077.1 - 4.2e-185 616.2 1.6 5.1e-185 615.9 1.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EPX75077.1 - 2e-17 62.2 0.1 3.5e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Hist_deacetyl PF00850.14 EPX75078.1 - 3.5e-91 305.7 0.0 5.4e-91 305.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EPX75078.1 - 3.3e-41 140.6 1.2 3.8e-41 140.4 0.1 1.7 2 0 0 2 2 2 1 Arb2 domain Whi5 PF08528.6 EPX75079.1 - 9e-10 37.8 0.3 1.6e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 Whi5 like DUF663 PF04950.7 EPX75080.1 - 4.2e-93 311.5 0.0 4.2e-93 311.5 0.0 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EPX75080.1 - 2.8e-28 97.2 0.0 8.8e-28 95.6 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EPX75080.1 - 7.8e-08 31.9 0.0 1.6e-05 24.4 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EPX75080.1 - 4.4e-05 23.6 0.1 0.00019 21.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EPX75080.1 - 0.00017 21.6 0.0 0.00049 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EPX75080.1 - 0.00025 20.9 0.2 0.0016 18.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EPX75080.1 - 0.00026 20.9 0.5 0.0011 18.9 0.0 2.3 2 1 0 2 2 1 1 50S ribosome-binding GTPase AAA PF00004.24 EPX75080.1 - 0.00058 20.0 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPX75080.1 - 0.0006 20.6 0.0 0.0006 20.6 0.0 3.8 2 1 0 2 2 1 1 AAA domain PduV-EutP PF10662.4 EPX75080.1 - 0.0014 18.1 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EPX75080.1 - 0.0015 18.9 0.2 0.0064 16.9 0.0 2.2 2 0 0 2 2 1 1 Miro-like protein AAA_19 PF13245.1 EPX75080.1 - 0.0021 17.7 0.1 0.0073 16.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 EPX75080.1 - 0.003 17.8 0.0 0.003 17.8 0.0 3.2 3 1 0 3 3 3 1 ABC transporter MobB PF03205.9 EPX75080.1 - 0.0032 17.1 0.2 0.011 15.4 0.1 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EPX75080.1 - 0.0046 16.9 0.0 0.024 14.5 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EPX75080.1 - 0.015 14.7 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 EPX75080.1 - 0.018 14.4 0.0 0.075 12.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EPX75080.1 - 0.033 14.5 0.0 0.033 14.5 0.0 3.7 3 1 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 EPX75080.1 - 0.038 14.1 0.5 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase cobW PF02492.14 EPX75080.1 - 0.051 13.0 0.1 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EPX75080.1 - 0.094 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ArgK PF03308.11 EPX75080.1 - 0.097 11.4 0.0 0.3 9.8 0.0 1.8 1 0 0 1 1 1 0 ArgK protein Viral_helicase1 PF01443.13 EPX75080.1 - 0.12 11.8 0.1 0.36 10.3 0.1 1.8 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EPX75080.1 - 0.12 12.0 2.8 0.12 12.1 0.1 2.1 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 EPX75080.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Adeno_IVa2 PF02456.10 EPX75080.1 - 0.18 10.3 0.0 0.31 9.6 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_11 PF13086.1 EPX75080.1 - 0.51 9.8 0.0 0.51 9.8 0.0 3.5 3 1 0 3 3 2 0 AAA domain GLE1 PF07817.8 EPX75081.1 - 9e-67 224.6 0.0 9e-67 224.6 0.0 2.3 2 1 0 2 2 2 1 GLE1-like protein LMBR1 PF04791.11 EPX75081.1 - 0.015 13.8 5.1 0.02 13.4 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SAPS PF04499.10 EPX75081.1 - 0.055 12.1 14.0 6.6 5.2 10.1 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein CAF-1_p150 PF11600.3 EPX75081.1 - 0.2 10.9 47.6 0.12 11.7 31.7 1.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GAGA_bind PF06217.7 EPX75081.1 - 1.8 8.4 15.2 2.7 7.8 10.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SprA-related PF12118.3 EPX75081.1 - 2 7.6 22.9 2.9 7.1 15.9 1.2 1 0 0 1 1 1 0 SprA-related family NARP1 PF12569.3 EPX75081.1 - 2.8 6.5 23.7 4.4 5.9 16.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Hid1 PF12722.2 EPX75081.1 - 5.5 4.5 14.0 8 3.9 9.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SNARE PF05739.14 EPX75082.1 - 2.2e-17 62.4 4.3 5.4e-17 61.2 1.4 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 EPX75082.1 - 1.5e-09 37.7 4.2 1.5e-09 37.7 2.9 2.7 2 2 0 2 2 2 1 Syntaxin-like protein Herpes_UL45 PF05473.7 EPX75082.1 - 0.054 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 UL45 protein DASH_Dad2 PF08654.5 EPX75082.1 - 0.066 13.2 8.8 1.8 8.6 0.0 3.2 1 1 1 3 3 3 0 DASH complex subunit Dad2 Peroxin-13_N PF04088.8 EPX75082.1 - 0.083 12.8 1.1 7.7 6.4 0.4 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Dispanin PF04505.7 EPX75082.1 - 0.13 11.7 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Herpes_US9 PF06072.6 EPX75082.1 - 0.19 11.6 0.7 0.34 10.7 0.5 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF4635 PF15466.1 EPX75082.1 - 0.25 10.6 5.0 0.71 9.1 0.0 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4635) DUF1664 PF07889.7 EPX75082.1 - 1.2 8.8 11.4 1.7 8.4 0.5 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF912 PF06024.7 EPX75082.1 - 1.5 8.9 6.1 0.36 10.9 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Cortex-I_coil PF09304.5 EPX75082.1 - 6.5 6.8 13.8 1.5 8.9 5.5 2.7 1 1 2 3 3 3 0 Cortexillin I, coiled coil APG6 PF04111.7 EPX75082.1 - 9.3 5.1 19.0 3.8 6.4 11.2 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 ubiquitin PF00240.18 EPX75083.1 - 6.1e-06 25.5 0.1 2.5e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EPX75083.1 - 6.5e-05 23.1 0.0 0.0003 20.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 EPX75083.1 - 0.069 12.8 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like E1-E2_ATPase PF00122.15 EPX75084.1 - 1.7e-79 266.0 0.4 3.9e-79 264.9 0.3 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPX75084.1 - 3.8e-46 156.9 3.5 3.8e-46 156.9 2.4 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPX75084.1 - 2.6e-29 103.1 0.0 8.2e-29 101.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPX75084.1 - 1.5e-16 60.1 0.0 2.7e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EPX75084.1 - 3.6e-14 51.9 0.0 9.4e-14 50.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EPX75084.1 - 8.2e-14 52.2 0.0 3.7e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPX75084.1 - 1.1e-06 28.4 0.8 9e-05 22.1 0.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Spore_IV_A PF09547.5 EPX75084.1 - 0.016 13.9 0.0 0.048 12.3 0.0 1.7 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) ATG_C PF09333.6 EPX75085.1 - 4.8e-25 87.5 0.0 9.1e-25 86.6 0.0 1.5 1 0 0 1 1 1 1 ATG C terminal domain ATG2_CAD PF13329.1 EPX75085.1 - 1.6e-14 53.7 1.1 6.9e-14 51.7 0.8 2.2 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.2 EPX75085.1 - 3.1e-08 33.1 1.7 2e-07 30.5 0.3 2.9 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Ribosomal_L37ae PF01780.14 EPX75086.1 - 3.9e-38 129.1 8.2 4.4e-38 129.0 5.7 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 EPX75086.1 - 0.018 14.4 1.3 0.095 12.1 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.1 EPX75086.1 - 0.13 12.5 1.2 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.2 EPX75086.1 - 0.19 11.5 4.3 0.31 10.8 3.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 EPX75086.1 - 0.25 10.9 0.2 0.25 10.9 0.2 1.7 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.5 EPX75086.1 - 0.37 10.7 0.1 0.37 10.7 0.1 1.9 2 0 0 2 2 2 0 Zinc ribbon domain Lar_restr_allev PF14354.1 EPX75086.1 - 0.82 10.0 6.6 7.2 6.9 4.6 2.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-tcix PF14952.1 EPX75086.1 - 3.2 7.1 7.1 1.7 8.0 2.5 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Tubulin PF00091.20 EPX75087.1 - 6.2e-71 238.6 0.0 8.6e-71 238.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPX75087.1 - 2.4e-49 166.5 0.0 4e-49 165.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EPX75087.1 - 0.00068 19.1 0.0 0.0017 17.8 0.0 1.8 1 0 0 1 1 1 1 Tubulin domain Brix PF04427.13 EPX75088.1 - 8.3e-40 136.4 0.4 1.4e-39 135.7 0.3 1.3 1 0 0 1 1 1 1 Brix domain EF_TS PF00889.14 EPX75089.1 - 4.7e-20 71.8 0.4 1e-19 70.7 0.1 1.7 1 1 1 2 2 2 1 Elongation factor TS Gcd10p PF04189.8 EPX75090.1 - 9.3e-77 258.0 4.4 4.5e-76 255.8 0.4 2.8 2 1 0 2 2 2 1 Gcd10p family LSM14 PF12701.2 EPX75091.1 - 8.8e-35 118.4 0.0 2e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EPX75091.1 - 1.2e-10 41.8 7.4 4.7e-07 30.2 0.3 2.4 1 1 1 2 2 2 2 FDF domain SM-ATX PF14438.1 EPX75091.1 - 6.6e-05 22.7 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.6 EPX75091.1 - 1.1 7.7 6.1 1.4 7.3 4.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF1772 PF08592.6 EPX75092.1 - 1.4e-15 57.2 2.6 1.6e-15 57.0 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Sex_peptide PF08138.6 EPX75092.1 - 0.02 14.7 0.4 0.045 13.5 0.3 1.6 1 0 0 1 1 1 0 Sex peptide (SP) family SE PF08491.5 EPX75092.1 - 0.077 11.8 0.1 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase WD40 PF00400.27 EPX75093.1 - 3e-20 71.2 8.1 3.8e-08 32.8 0.5 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EPX75093.1 - 3.9e-17 61.9 0.0 9.2e-17 60.7 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EPX75093.1 - 0.00016 21.4 0.1 0.00089 19.0 0.1 2.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Aha1_N PF09229.6 EPX75094.1 - 1.6e-30 105.7 0.1 2.4e-30 105.1 0.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EPX75094.1 - 1.1e-19 70.7 0.0 2.3e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EPX75094.1 - 0.0038 17.3 0.1 0.016 15.4 0.0 1.9 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport SNARE_assoc PF09335.6 EPX75095.1 - 1.5e-07 31.6 1.5 1.5e-07 31.6 1.1 2.3 1 1 2 3 3 3 1 SNARE associated Golgi protein IncA PF04156.9 EPX75095.1 - 0.12 12.0 0.2 1.5 8.3 0.0 2.6 3 0 0 3 3 3 0 IncA protein YtpI PF14007.1 EPX75095.1 - 0.5 10.3 3.0 17 5.4 0.1 2.8 2 1 0 2 2 2 0 YtpI-like protein NPL4 PF05021.10 EPX75096.1 - 3.4e-101 338.4 0.0 4.8e-101 337.9 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EPX75096.1 - 9.4e-68 226.4 0.1 1.5e-67 225.8 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EPX75096.1 - 2.7e-07 30.7 0.0 1.5e-06 28.4 0.0 2.3 3 0 0 3 3 3 1 Nuclear pore localisation protein NPL4 DUF3320 PF11784.3 EPX75096.1 - 0.08 12.4 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) PX PF00787.19 EPX75097.1 - 2.2e-23 82.2 0.6 2.2e-23 82.2 0.4 2.0 2 1 1 3 3 3 1 PX domain Peptidase_S9 PF00326.16 EPX75098.1 - 2.9e-53 180.2 0.0 4.1e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPX75098.1 - 1.8e-08 34.2 0.0 3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EPX75098.1 - 2.8e-06 26.0 0.1 0.00051 18.6 0.1 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Lambda_Kil PF06301.6 EPX75098.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein Histidinol_dh PF00815.15 EPX75099.1 - 1.5e-163 544.2 0.6 1.8e-163 544.0 0.4 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Usp PF00582.21 EPX75099.1 - 0.16 12.1 1.5 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Universal stress protein family DUF2153 PF09921.4 EPX75100.1 - 0.0011 18.5 1.9 0.0016 18.0 1.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2153) Cytokin-bind PF09265.5 EPX75100.1 - 0.041 13.0 3.5 0.048 12.7 1.9 1.4 1 1 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF1664 PF07889.7 EPX75100.1 - 0.11 12.2 4.2 0.12 12.2 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Tn7_Tnp_TnsA_C PF08721.6 EPX75100.1 - 0.3 11.1 3.1 0.44 10.5 0.1 2.4 1 1 0 2 2 2 0 TnsA endonuclease C terminal Laminin_I PF06008.9 EPX75100.1 - 0.33 10.2 18.5 0.036 13.3 7.2 2.0 1 1 1 2 2 2 0 Laminin Domain I DUF2951 PF11166.3 EPX75100.1 - 0.37 10.6 6.1 4.4 7.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Retrotrans_gag PF03732.12 EPX75100.1 - 0.58 10.2 4.9 1.3 9.1 3.4 1.7 1 1 0 1 1 1 0 Retrotransposon gag protein ACCA PF03255.9 EPX75100.1 - 1.9 8.0 6.4 0.94 9.0 0.3 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1826 PF08856.6 EPX75100.1 - 3.3 7.4 6.5 0.78 9.4 1.3 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1826) TEX13 PF15186.1 EPX75100.1 - 4.3 6.9 9.0 1.4 8.4 1.9 2.1 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF305 PF03713.8 EPX75100.1 - 9.7 6.0 14.2 5.8 6.7 3.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF305) WD40 PF00400.27 EPX75101.1 - 1.2e-33 113.7 10.1 1.2e-08 34.4 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat RNA_pol_3_Rpc31 PF11705.3 EPX75101.1 - 0.47 10.3 29.3 0.52 10.1 3.0 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Hid1 PF12722.2 EPX75101.1 - 4.2 4.9 10.1 7.8 4.0 7.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HA2 PF04408.18 EPX75102.1 - 1.5e-26 92.3 0.0 1e-25 89.7 0.0 2.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EPX75102.1 - 1.3e-22 79.7 0.0 3.8e-22 78.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EPX75102.1 - 3.7e-14 52.3 0.0 9.7e-14 50.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPX75102.1 - 2.4e-07 30.4 0.1 1.1e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPX75102.1 - 1.1e-05 25.5 0.0 3.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EPX75102.1 - 0.00066 19.1 0.1 0.0033 16.8 0.1 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 EPX75102.1 - 0.0014 17.6 2.4 0.0052 15.7 1.6 1.9 1 1 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 EPX75102.1 - 0.0092 15.1 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 KaiC Flavi_DEAD PF07652.9 EPX75102.1 - 0.028 14.1 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.22 EPX75102.1 - 0.034 14.4 1.7 0.2 11.9 0.0 2.8 2 1 1 3 3 3 0 ABC transporter NB-ARC PF00931.17 EPX75102.1 - 0.047 12.5 0.1 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.10 EPX75102.1 - 0.07 12.9 13.0 0.27 11.0 0.0 4.0 4 1 0 4 4 4 0 Type III restriction enzyme, res subunit CRT10 PF08728.5 EPX75102.1 - 2.6 5.9 8.2 4 5.3 5.7 1.2 1 0 0 1 1 1 0 CRT10 CDC73 PF05179.9 EPX75103.1 - 1.2e-89 300.2 0.4 1.6e-89 299.9 0.3 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family LRRNT_2 PF08263.7 EPX75103.1 - 0.044 13.7 0.5 7.5 6.6 0.1 2.8 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain tRNA-synt_2 PF00152.15 EPX75104.1 - 2.6e-89 299.2 0.0 3.8e-89 298.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPX75104.1 - 4.1e-10 39.3 0.0 7.5e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EPX75104.1 - 8.8e-07 28.3 0.0 0.0058 15.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EPX75104.1 - 0.0045 16.5 0.2 2.2 7.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Nucleopor_Nup85 PF07575.8 EPX75105.1 - 1.9e-118 396.1 13.4 2.2e-118 395.9 9.3 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin SLAC1 PF03595.12 EPX75106.1 - 1.3e-67 227.7 49.4 1.7e-67 227.4 34.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ArfGap PF01412.13 EPX75107.1 - 2.8e-31 107.7 0.2 2.8e-31 107.7 0.1 2.7 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.24 EPX75107.1 - 7.6e-14 51.7 0.2 3.4e-13 49.6 0.1 2.2 2 0 0 2 2 2 1 PH domain Ribosomal_S24e PF01282.14 EPX75108.1 - 2.9e-34 116.6 0.0 4.8e-34 116.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Pro_isomerase PF00160.16 EPX75109.1 - 2.7e-34 118.6 0.0 4.3e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EPX75109.1 - 5e-17 61.3 0.2 8.7e-17 60.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX75109.1 - 1.3e-12 47.5 0.1 2.5e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX75109.1 - 6.6e-11 41.8 0.3 1.8e-10 40.4 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zea_mays_MuDR PF05928.6 EPX75109.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Acetyltransf_8 PF13523.1 EPX75110.1 - 7.1e-47 159.0 1.8 9.5e-47 158.6 1.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPX75110.1 - 0.014 15.5 0.1 0.027 14.6 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GTP_EFTU PF00009.22 EPX75111.1 - 3.3e-40 137.5 0.0 5.3e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EPX75111.1 - 3.1e-36 123.2 0.4 7.6e-36 122.0 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EPX75111.1 - 9.4e-13 48.0 0.9 2.3e-12 46.8 0.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPX75111.1 - 0.014 15.3 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPX75111.1 - 0.076 12.8 0.2 0.49 10.2 0.1 2.2 1 1 0 2 2 2 0 Dynamin family YdjO PF14169.1 EPX75111.1 - 0.1 12.0 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO Ribosomal_L5_C PF00673.16 EPX75112.1 - 1.6e-23 82.2 0.0 2.2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EPX75112.1 - 4e-20 71.3 0.1 1e-19 70.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 CPSase_L_D2 PF02786.12 EPX75113.1 - 1.1e-79 266.6 0.0 1.8e-79 265.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EPX75113.1 - 4.5e-63 212.2 0.0 7.5e-63 211.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EPX75113.1 - 5.1e-35 119.8 0.1 1.1e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EPX75113.1 - 5.2e-28 97.1 0.0 2.2e-27 95.1 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EPX75113.1 - 2e-23 83.3 0.0 3.7e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EPX75113.1 - 2e-21 76.5 0.1 3.7e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPX75113.1 - 1.5e-17 63.3 0.0 1.6e-16 59.9 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EPX75113.1 - 3.6e-16 58.5 3.0 8.6e-16 57.3 2.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EPX75113.1 - 1.4e-11 43.8 0.2 7.9e-06 25.4 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EPX75113.1 - 4.2e-10 39.3 0.0 7.6e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EPX75113.1 - 1.5e-08 34.1 0.0 3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EPX75113.1 - 2.9e-05 23.9 0.0 8.5e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EPX75113.1 - 7.3e-05 22.3 0.0 0.00061 19.3 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_2 PF12700.2 EPX75113.1 - 0.00044 19.5 0.1 0.022 13.9 0.1 2.2 1 1 1 2 2 2 1 HlyD family secretion protein HlyD PF00529.15 EPX75113.1 - 0.00062 19.1 0.3 0.62 9.3 0.0 3.2 3 0 0 3 3 3 1 HlyD family secretion protein HlyD_3 PF13437.1 EPX75113.1 - 0.0012 19.1 0.1 2.5 8.4 0.0 2.9 1 1 1 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.1 EPX75113.1 - 0.036 13.7 1.6 0.15 11.7 1.1 2.1 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain HAD PF12710.2 EPX75114.1 - 3.8e-09 36.9 0.0 4.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EPX75114.1 - 1.3e-07 31.0 0.0 0.00039 19.6 0.0 2.1 1 1 1 2 2 2 2 Putative Phosphatase DUF4484 PF14831.1 EPX75115.1 - 0.044 13.8 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Enolase_C PF00113.17 EPX75116.1 - 3.6e-146 485.7 0.0 4.9e-146 485.3 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EPX75116.1 - 2.1e-56 189.5 0.1 3.3e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EPX75116.1 - 0.034 14.1 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 Enolase C-terminal domain-like Tim44 PF04280.10 EPX75118.1 - 5.5e-31 107.5 0.0 1e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain Peptidase_M24 PF00557.19 EPX75119.1 - 2.1e-41 141.7 0.0 2.8e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CDC45 PF02724.9 EPX75119.1 - 3.5 5.5 10.0 4.6 5.1 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 EPX75119.1 - 9.6 6.2 10.1 30 4.6 7.0 1.8 1 0 0 1 1 1 0 YqfQ-like protein ALS_ss_C PF10369.4 EPX75120.1 - 3.1e-20 71.6 0.1 8.9e-19 66.9 0.0 2.5 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.20 EPX75120.1 - 8.5e-12 44.2 0.2 1.5e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EPX75120.1 - 1e-09 38.0 0.1 2.1e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 ACT domain NIL PF09383.5 EPX75120.1 - 0.11 12.1 0.0 8 6.1 0.0 2.4 2 0 0 2 2 2 0 NIL domain Glyco_hydro_15 PF00723.16 EPX75121.1 - 6.3e-74 249.1 0.0 7.8e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 WD40 PF00400.27 EPX75122.1 - 4.3e-17 61.2 11.2 1.5e-06 27.8 0.2 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Rax2 PF12768.2 EPX75122.1 - 0.013 14.6 0.0 0.04 13.1 0.0 1.8 2 0 0 2 2 2 0 Cortical protein marker for cell polarity DPPIV_N PF00930.16 EPX75122.1 - 0.018 13.6 1.8 4.8 5.6 0.3 3.2 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region AAA PF00004.24 EPX75123.1 - 3.3e-14 53.2 0.0 6.5e-13 49.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPX75123.1 - 2.3e-11 44.0 0.0 2.1e-10 40.8 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPX75123.1 - 8.8e-11 42.0 0.0 8.5e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Cdc6_C PF09079.6 EPX75123.1 - 1.5e-09 37.4 0.1 8.2e-09 35.0 0.0 2.2 2 0 0 2 2 2 1 CDC6, C terminal NACHT PF05729.7 EPX75123.1 - 6.6e-05 22.6 0.0 0.0002 21.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 EPX75123.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EPX75123.1 - 0.0033 16.3 0.0 0.0061 15.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Pox_A32 PF04665.7 EPX75123.1 - 0.023 14.0 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.1 EPX75123.1 - 0.024 14.5 0.0 0.072 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EPX75123.1 - 0.029 14.0 0.2 0.11 12.2 0.2 2.0 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EPX75123.1 - 0.03 13.7 0.1 0.084 12.3 0.1 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EPX75123.1 - 0.069 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 EPX75123.1 - 0.072 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.1 EPX75123.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EPX75123.1 - 2.7 7.4 6.7 0.73 9.3 1.4 2.3 2 1 0 2 2 2 0 AAA domain Ribosomal_L28 PF00830.14 EPX75124.1 - 1.2e-16 60.3 0.3 2e-16 59.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L28 family SMAP PF15477.1 EPX75125.1 - 9.1e-10 38.6 4.9 9.1e-10 38.6 3.4 3.0 2 1 0 2 2 2 1 Small acidic protein family Vfa1 PF08432.5 EPX75125.1 - 0.53 10.2 17.7 0.65 10.0 12.3 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 eIF-3c_N PF05470.7 EPX75125.1 - 1.7 6.6 11.3 1.8 6.5 7.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.9 EPX75125.1 - 1.8 6.5 12.1 2.2 6.2 8.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Allexi_40kDa PF05549.6 EPX75125.1 - 2.7 7.2 5.7 3.5 6.8 3.9 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein NARP1 PF12569.3 EPX75125.1 - 3.8 6.1 15.0 4.7 5.8 10.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDHD PF02862.12 EPX75125.1 - 7.4 6.2 9.5 8.7 6.0 6.6 1.3 1 0 0 1 1 1 0 DDHD domain DUF3807 PF12720.2 EPX75125.1 - 7.5 6.6 17.6 1.2 9.2 9.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Vma12 PF11712.3 EPX75125.1 - 7.9 6.1 7.2 13 5.5 5.0 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase UPF0029 PF01205.14 EPX75126.1 - 8.1e-16 57.6 0.0 2e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RNA_pol_Rpb8 PF03870.10 EPX75127.1 - 1.5e-41 141.8 1.7 1.3e-40 138.7 1.2 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb8 Epimerase PF01370.16 EPX75128.1 - 2.8e-05 23.6 0.0 6e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPX75128.1 - 0.00015 21.8 0.0 0.00032 20.7 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPX75128.1 - 0.00094 18.1 0.0 0.0035 16.3 0.0 2.0 3 0 0 3 3 3 1 Male sterility protein Semialdhyde_dh PF01118.19 EPX75128.1 - 0.0082 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF1886 PF09171.5 EPX75128.1 - 0.043 12.8 0.1 0.089 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) 3Beta_HSD PF01073.14 EPX75128.1 - 0.075 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SRR1 PF07985.7 EPX75129.1 - 1.2e-09 37.9 0.0 2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 SRR1 DUF4508 PF14969.1 EPX75129.1 - 0.11 12.4 0.1 20 5.2 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4508) DNA_pol_phi PF04931.8 EPX75130.1 - 1.4e-201 671.3 22.0 1.7e-201 671.0 15.2 1.1 1 0 0 1 1 1 1 DNA polymerase phi Abhydro_lipase PF04083.11 EPX75131.1 - 6.1e-23 79.9 0.0 1.6e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EPX75131.1 - 1.7e-11 44.1 0.0 2.8e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPX75131.1 - 5.4e-08 32.7 0.0 4.8e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPX75131.1 - 2.9e-07 30.6 0.0 1.3e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EPX75131.1 - 2.1e-06 27.3 0.0 0.0027 17.1 0.0 3.0 3 0 0 3 3 3 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EPX75131.1 - 3.6e-06 26.5 0.4 0.0026 17.2 0.0 2.9 4 0 0 4 4 4 2 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EPX75131.1 - 0.011 15.3 0.0 0.074 12.6 0.0 2.2 3 0 0 3 3 3 0 PGAP1-like protein DUF2974 PF11187.3 EPX75131.1 - 0.085 12.2 0.0 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) BAAT_C PF08840.6 EPX75131.1 - 0.11 12.1 0.1 8.3 6.0 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Bot1p PF12298.3 EPX75132.1 - 1.7e-32 112.7 0.8 2.5e-32 112.1 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein HTH_28 PF13518.1 EPX75132.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain WD40 PF00400.27 EPX75133.1 - 8.2e-19 66.7 11.4 1.3e-07 31.2 0.1 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat SID-1_RNA_chan PF13965.1 EPX75133.1 - 1.6 6.8 2.3 2.6 6.0 1.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.7 EPX75133.1 - 6.3 6.6 18.8 4.8 6.9 7.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TPR_11 PF13414.1 EPX75134.1 - 4.3e-09 35.8 1.5 3.2e-07 29.8 0.4 2.7 2 1 1 3 3 3 1 TPR repeat TPR_2 PF07719.12 EPX75134.1 - 6.2e-05 22.6 2.2 0.0032 17.2 1.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPX75134.1 - 0.00014 21.2 2.8 0.0019 17.7 0.9 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPX75134.1 - 0.00019 20.9 0.7 0.013 15.2 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPX75134.1 - 0.0013 18.3 4.0 0.24 11.2 0.4 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPX75134.1 - 0.0046 16.0 0.1 0.0082 15.2 0.0 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPX75134.1 - 0.013 16.1 0.2 0.091 13.4 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPX75134.1 - 0.013 16.0 2.6 0.14 12.8 0.6 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat Prolamin_like PF05617.6 EPX75134.1 - 0.022 14.9 0.3 0.64 10.1 0.1 3.0 3 0 0 3 3 3 0 Prolamin-like TPR_9 PF13371.1 EPX75134.1 - 0.067 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPX75134.1 - 0.24 11.7 2.5 7.2 7.0 0.5 3.5 3 2 1 4 4 4 0 Tetratricopeptide repeat ABC1 PF03109.11 EPX75135.1 - 1.5e-34 118.4 0.0 2.6e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family GDI PF00996.13 EPX75136.1 - 2.5e-48 164.4 0.6 4.8e-48 163.5 0.0 1.6 2 0 0 2 2 2 1 GDP dissociation inhibitor AA_permease_2 PF13520.1 EPX75137.1 - 1.1e-61 208.7 51.6 1.3e-61 208.4 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPX75137.1 - 3e-12 45.6 43.2 4e-12 45.2 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4234 PF14018.1 EPX75137.1 - 0.021 14.5 0.4 0.021 14.5 0.3 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4234) HA2 PF04408.18 EPX75138.1 - 3.3e-18 65.6 0.0 1.6e-17 63.3 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPX75138.1 - 5.7e-16 58.1 0.2 2e-15 56.4 0.2 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPX75138.1 - 2.3e-12 46.7 0.0 1e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EPX75138.1 - 3.5e-10 39.7 0.2 1.3e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EPX75138.1 - 2.1e-05 24.6 0.0 9.9e-05 22.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EPX75138.1 - 0.0073 15.2 0.0 0.018 13.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein zf-RING_2 PF13639.1 EPX75139.1 - 1.3e-10 40.8 8.9 2.1e-10 40.2 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPX75139.1 - 8e-06 25.4 7.0 1.3e-05 24.8 4.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPX75139.1 - 0.00053 19.5 8.9 0.00087 18.8 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPX75139.1 - 0.0013 18.7 9.6 0.0021 18.0 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPX75139.1 - 0.0056 16.7 3.8 0.013 15.5 2.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EPX75139.1 - 0.011 15.4 5.5 0.018 14.7 3.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPX75139.1 - 0.49 10.2 2.6 1.2 9.0 1.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EPX75139.1 - 1.2 9.2 4.8 2 8.5 3.3 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 EPX75139.1 - 1.5 8.8 7.3 2.8 7.9 5.1 1.4 1 0 0 1 1 1 0 RING-like domain MFS_1 PF07690.11 EPX75140.1 - 9.1e-37 126.5 32.2 9.1e-37 126.5 22.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX75140.1 - 8.3e-11 41.1 26.2 2.1e-10 39.8 18.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPX75141.1 - 4.2e-39 134.2 37.6 4.2e-39 134.2 26.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX75141.1 - 6.4e-08 31.6 39.5 5.9e-06 25.1 26.5 3.2 1 1 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.20 EPX75142.1 - 4.2e-43 147.3 0.1 7e-24 84.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPX75142.1 - 8.1e-15 54.5 0.1 3.9e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 EPX75142.1 - 0.092 12.0 0.9 0.13 11.6 0.1 1.6 2 0 0 2 2 2 0 RIO1 family Cyclin_N PF00134.18 EPX75143.1 - 3.4e-16 58.9 0.7 6.8e-11 41.8 0.1 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPX75143.1 - 0.012 15.5 0.7 1.3 9.0 0.0 2.3 1 1 0 2 2 2 0 Cyclin, C-terminal domain TFIIB PF00382.14 EPX75143.1 - 0.077 12.8 1.2 0.26 11.1 0.2 2.2 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Palm_thioest PF02089.10 EPX75144.1 - 1.8e-46 158.3 0.0 3e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PAP2 PF01569.16 EPX75144.1 - 1.4e-14 53.9 3.4 2.5e-14 53.0 2.3 1.5 1 0 0 1 1 1 1 PAP2 superfamily Fungal_trans PF04082.13 EPX75145.1 - 5.1e-23 81.2 1.5 1.1e-22 80.1 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.22 EPX75146.1 - 1.7e-66 219.9 3.9 1.1e-22 79.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CIMR PF00878.13 EPX75147.1 - 6.5e-12 45.4 0.2 4.2e-07 29.8 0.2 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 EPX75147.1 - 9.3e-11 41.2 0.1 1.1e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 EPX75147.1 - 0.021 14.0 1.2 0.31 10.2 0.5 2.4 2 1 0 2 2 2 0 Autophagy-related protein 27 DUF3810 PF12725.2 EPX75147.1 - 0.28 10.0 1.2 0.39 9.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Fungal_trans PF04082.13 EPX75148.1 - 1.3e-22 79.9 0.7 2.8e-22 78.8 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX75148.1 - 3.3e-10 39.7 15.0 5.7e-10 38.9 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TENA_THI-4 PF03070.11 EPX75149.1 - 4e-05 23.4 0.4 0.0029 17.3 0.0 2.3 2 0 0 2 2 2 2 TENA/THI-4/PQQC family CLU PF13236.1 EPX75150.1 - 9.3e-75 250.8 0.0 1.6e-74 250.0 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EPX75150.1 - 3.7e-32 111.5 0.5 2.6e-31 108.8 0.0 2.7 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EPX75150.1 - 2.5e-16 59.3 5.0 9.4e-08 31.8 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat CLU_N PF15044.1 EPX75150.1 - 3.5e-13 49.4 0.1 1.3e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 EPX75150.1 - 9e-08 31.7 0.9 0.034 14.0 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPX75150.1 - 0.0021 17.5 0.0 3.1 7.5 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF727 PF05303.7 EPX75150.1 - 0.0067 16.2 0.1 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.1 EPX75150.1 - 0.011 15.4 0.0 8.6 6.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.13 EPX75151.1 - 7.6e-26 90.5 2.5 1.4e-25 89.7 1.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPX75151.1 - 8.6e-12 44.7 12.6 1.9e-11 43.6 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAG PF02179.11 EPX75153.1 - 2.6e-12 46.6 0.1 6.3e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EPX75153.1 - 0.0037 16.6 0.1 0.013 14.8 0.0 2.0 1 1 1 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EPX75153.1 - 0.017 14.7 0.0 0.083 12.5 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF3514 PF12027.3 EPX75153.1 - 0.051 12.8 0.1 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3514) DUF1242 PF06842.7 EPX75154.1 - 1.4e-16 59.6 1.1 2e-16 59.2 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) RabGAP-TBC PF00566.13 EPX75155.1 - 5.5e-53 179.6 0.4 8e-53 179.0 0.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain KAR9 PF08580.5 EPX75155.1 - 5.4 5.1 7.8 7.5 4.6 5.4 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SHNi-TPR PF10516.4 EPX75156.1 - 2.6e-15 55.3 5.1 1.6e-14 52.8 0.7 3.1 3 1 0 3 3 3 1 SHNi-TPR TPR_11 PF13414.1 EPX75156.1 - 1.3e-06 27.9 5.2 0.0004 19.9 0.1 3.1 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EPX75156.1 - 6.5e-05 22.5 6.7 0.0068 16.2 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPX75156.1 - 0.00029 20.7 7.4 0.29 11.0 0.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPX75156.1 - 0.0048 16.4 3.4 0.092 12.3 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPX75156.1 - 0.019 15.3 4.1 6.5 7.1 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPX75156.1 - 0.024 15.3 7.4 0.2 12.3 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat ODC_AZ PF02100.12 EPX75157.1 - 1.6e-21 75.8 0.0 2.3e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Syja_N PF02383.13 EPX75158.1 - 1.8e-44 151.7 0.0 3e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EPX75158.1 - 1.4e-21 77.5 0.1 3.1e-21 76.4 0.1 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EPX75158.1 - 0.0024 17.4 0.2 0.0074 15.8 0.1 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase ATP_bind_4 PF01902.12 EPX75159.1 - 8e-40 136.5 0.0 1.8e-39 135.3 0.0 1.6 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 EPX75159.1 - 3.8e-18 65.3 0.0 5e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 Endoribonuclease L-PSP FAE1_CUT1_RppA PF08392.7 EPX75159.1 - 0.077 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein DUF3074 PF11274.3 EPX75160.1 - 2.2e-26 92.6 0.0 1.3e-25 90.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) Oxidored_FMN PF00724.15 EPX75161.1 - 9.4e-114 379.9 0.0 1.1e-113 379.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family 2-Hacid_dh_C PF02826.14 EPX75162.1 - 1.7e-52 177.1 0.0 3.5e-52 176.1 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPX75162.1 - 2.9e-14 52.6 0.0 3.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPX75162.1 - 8.6e-05 22.4 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EPX75162.1 - 0.006 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EPX75162.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 EPX75162.1 - 0.021 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 EPX75162.1 - 0.17 11.4 0.0 0.82 9.3 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Proteasome PF00227.21 EPX75163.1 - 6.9e-23 80.9 0.0 8.1e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 EPX75165.1 - 1.2e-30 104.2 23.4 9.2e-11 41.1 0.5 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EPX75165.1 - 0.00012 21.8 0.0 0.0067 16.1 0.0 2.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPX75165.1 - 0.00027 19.1 0.6 0.45 8.5 0.0 3.1 2 1 0 3 3 3 3 Nucleoporin Nup120/160 PITH PF06201.8 EPX75166.1 - 3.1e-42 143.9 0.4 4.2e-42 143.5 0.3 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EPX75166.1 - 6.1e-26 90.1 0.0 1e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EPX75166.1 - 5.1e-06 26.5 0.2 2.5e-05 24.3 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EPX75166.1 - 2.2e-05 24.6 0.0 8.8e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Sad1_UNC PF07738.8 EPX75166.1 - 0.0032 17.2 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Thioredoxin_7 PF13899.1 EPX75166.1 - 0.0034 17.3 0.1 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EPX75166.1 - 0.025 14.2 0.0 0.067 12.8 0.0 1.7 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_9 PF14595.1 EPX75166.1 - 0.042 13.4 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.6 EPX75166.1 - 0.083 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DSBA PF01323.15 EPX75166.1 - 0.19 11.2 0.6 0.87 9.1 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain UCH PF00443.24 EPX75167.1 - 6.9e-28 97.4 0.2 1.2e-27 96.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPX75167.1 - 4.2e-11 42.7 0.7 4.2e-11 42.7 0.5 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EPX75167.1 - 0.00021 20.8 0.3 0.0011 18.5 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PI3_PI4_kinase PF00454.22 EPX75168.1 - 6.2e-40 137.1 0.0 2e-39 135.4 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EPX75168.1 - 4.1e-18 65.2 0.0 1.2e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) OmpH PF03938.9 EPX75169.1 - 0.06 13.2 8.1 0.071 13.0 5.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SAS4 PF15460.1 EPX75169.1 - 0.16 11.8 9.2 0.52 10.2 3.8 2.0 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF775 PF05603.7 EPX75169.1 - 0.17 11.3 2.1 0.2 11.1 1.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF775) Exonuc_VII_L PF02601.10 EPX75169.1 - 0.19 10.9 9.8 0.19 10.8 6.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C3HC PF07967.8 EPX75169.1 - 0.21 11.3 4.4 0.23 11.2 2.4 1.5 1 1 0 1 1 1 0 C3HC zinc finger-like TEX13 PF15186.1 EPX75169.1 - 0.28 10.7 7.8 0.36 10.3 5.4 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family P63C PF10546.4 EPX75169.1 - 0.34 10.8 2.4 4 7.4 0.2 2.2 2 1 0 2 2 2 0 P63C domain RNA_GG_bind PF10258.4 EPX75169.1 - 0.38 10.4 4.0 0.86 9.3 0.5 2.5 2 2 0 2 2 2 0 PHAX RNA-binding domain DUF4510 PF14971.1 EPX75169.1 - 1.1 9.3 7.3 1.2 9.3 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4510) IncA PF04156.9 EPX75169.1 - 2.5 7.6 12.2 3.1 7.3 8.5 1.3 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 EPX75169.1 - 2.8 6.8 12.2 3 6.6 8.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FimP PF09766.4 EPX75170.1 - 8e-16 58.0 14.5 8e-16 58.0 10.1 1.9 2 0 0 2 2 2 1 Fms-interacting protein UxuA PF03786.8 EPX75170.1 - 0.005 15.4 0.5 0.0065 15.0 0.3 1.1 1 0 0 1 1 1 1 D-mannonate dehydratase (UxuA) DUF91 PF01939.11 EPX75170.1 - 0.025 13.7 0.1 0.044 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF91 HAUS5 PF14817.1 EPX75170.1 - 0.64 8.5 18.3 0.028 12.9 5.1 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 Acetyltransf_3 PF13302.1 EPX75171.1 - 5.9e-20 71.8 0.0 7.1e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPX75171.1 - 2.4e-06 27.5 0.0 5.5e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPX75171.1 - 9.5e-05 22.3 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EPX75171.1 - 0.00014 21.5 0.0 0.00034 20.3 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPX75171.1 - 0.015 15.3 0.0 0.025 14.7 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPX75171.1 - 0.031 14.4 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AstA PF04958.7 EPX75171.1 - 0.044 12.2 0.0 0.069 11.5 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Ribosomal_L38e PF01781.13 EPX75172.1 - 2.6e-35 119.9 3.8 2.9e-35 119.8 2.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family M16C_assoc PF08367.6 EPX75173.1 - 5.4e-74 248.1 1.4 3.5e-73 245.4 0.4 2.2 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EPX75173.1 - 1.1e-33 116.4 0.8 9.6e-23 80.7 0.0 3.4 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EPX75173.1 - 7e-09 35.5 0.0 3.4e-06 26.9 0.0 3.5 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) DUF2347 PF09804.4 EPX75174.1 - 1.8e-41 142.2 0.3 2.8e-41 141.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) APP_E2 PF12925.2 EPX75174.1 - 0.14 11.6 0.1 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein DUF4386 PF14329.1 EPX75174.1 - 0.21 11.0 3.5 0.45 9.9 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) ATP_bind_1 PF03029.12 EPX75175.1 - 1.8e-85 286.2 0.1 1.8e-85 286.2 0.1 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EPX75175.1 - 6e-08 32.3 0.1 7e-07 28.8 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 EPX75175.1 - 4.1e-07 29.5 0.1 1.2e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EPX75175.1 - 3.7e-06 27.7 0.4 3.9e-05 24.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 EPX75175.1 - 6.4e-06 25.7 0.1 0.00011 21.6 0.0 2.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EPX75175.1 - 4e-05 23.1 0.0 0.002 17.6 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Arf PF00025.16 EPX75175.1 - 5.1e-05 22.5 0.0 0.03 13.5 0.0 3.1 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.1 EPX75175.1 - 5.9e-05 23.2 0.1 0.0005 20.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EPX75175.1 - 9.6e-05 21.9 1.0 0.00095 18.6 0.6 2.2 1 1 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 EPX75175.1 - 0.00012 21.9 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EPX75175.1 - 0.00012 21.3 0.0 0.0062 15.8 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EPX75175.1 - 0.00018 22.0 1.7 0.014 15.9 0.1 2.8 2 1 0 2 2 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPX75175.1 - 0.00026 20.9 0.1 0.00074 19.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPX75175.1 - 0.00048 19.3 0.1 0.25 10.5 0.0 2.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EPX75175.1 - 0.00072 19.5 0.0 0.0023 17.9 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.1 EPX75175.1 - 0.00081 19.7 1.9 0.0031 17.8 0.0 2.8 3 1 0 3 3 3 1 AAA domain NACHT PF05729.7 EPX75175.1 - 0.00088 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EPX75175.1 - 0.0011 17.9 0.6 0.0077 15.1 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain UvrD-helicase PF00580.16 EPX75175.1 - 0.0014 17.9 1.4 0.65 9.2 0.0 2.4 3 0 0 3 3 2 2 UvrD/REP helicase N-terminal domain Ras PF00071.17 EPX75175.1 - 0.0015 17.9 0.0 0.55 9.6 0.0 2.5 2 0 0 2 2 2 1 Ras family Dynamin_N PF00350.18 EPX75175.1 - 0.002 17.9 3.9 0.0049 16.6 0.1 2.8 2 1 0 2 2 2 1 Dynamin family ArgK PF03308.11 EPX75175.1 - 0.002 16.9 0.0 0.92 8.2 0.0 2.6 2 1 0 2 2 2 1 ArgK protein AAA_14 PF13173.1 EPX75175.1 - 0.0022 17.8 0.2 0.0074 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 EPX75175.1 - 0.0025 16.5 6.2 0.015 14.0 0.0 3.1 2 2 1 3 3 3 1 G-protein alpha subunit Zeta_toxin PF06414.7 EPX75175.1 - 0.0027 16.8 0.0 0.0067 15.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin T2SE PF00437.15 EPX75175.1 - 0.0033 16.3 0.0 0.0082 15.0 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 EPX75175.1 - 0.0052 16.3 0.0 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EPX75175.1 - 0.0058 16.9 1.1 0.04 14.2 0.5 2.1 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EPX75175.1 - 0.0066 15.4 0.1 0.013 14.5 0.1 1.6 1 1 0 1 1 1 1 KAP family P-loop domain Viral_helicase1 PF01443.13 EPX75175.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.4 EPX75175.1 - 0.0074 15.7 0.1 0.13 11.7 0.0 2.7 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EPX75175.1 - 0.0091 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Pox_A32 PF04665.7 EPX75175.1 - 0.0094 15.2 0.2 0.036 13.3 0.0 2.0 2 1 1 3 3 3 1 Poxvirus A32 protein NTPase_1 PF03266.10 EPX75175.1 - 0.013 15.1 0.0 0.09 12.4 0.0 2.2 1 1 0 1 1 1 0 NTPase MobB PF03205.9 EPX75175.1 - 0.014 15.0 0.0 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EPX75175.1 - 0.014 15.0 3.1 0.27 10.8 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EPX75175.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 EPX75175.1 - 0.016 14.6 0.1 0.085 12.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 EPX75175.1 - 0.03 13.5 0.1 0.088 12.0 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 EPX75175.1 - 0.035 14.4 0.1 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter DUF258 PF03193.11 EPX75175.1 - 0.044 12.9 0.2 0.26 10.4 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 EPX75175.1 - 0.065 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EPX75175.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Rad52_Rad22 PF04098.10 EPX75176.1 - 4.6e-59 198.5 0.0 6.9e-59 197.9 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein UPF0203 PF05254.7 EPX75177.1 - 2.9e-27 94.2 4.8 3.2e-27 94.1 3.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EPX75177.1 - 0.042 13.6 4.0 0.64 9.8 2.8 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 EPX75177.1 - 0.05 13.6 2.0 0.23 11.4 1.4 1.9 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Aromatic_hydrox PF11723.3 EPX75177.1 - 0.086 12.1 0.1 0.088 12.0 0.1 1.1 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase UCR_hinge PF02320.11 EPX75177.1 - 0.85 9.5 3.9 11 6.0 2.5 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein GRAB PF10375.4 EPX75178.1 - 2.4e-07 30.1 1.1 5.4e-07 28.9 0.7 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EPX75178.1 - 0.0025 17.0 19.0 0.0091 15.2 7.1 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein bZIP_1 PF00170.16 EPX75178.1 - 0.034 14.1 1.8 0.034 14.1 1.2 5.5 3 1 1 4 4 4 0 bZIP transcription factor DUF777 PF05606.6 EPX75178.1 - 0.78 8.8 7.3 0.053 12.6 0.9 2.1 2 1 1 3 3 3 0 Borrelia burgdorferi protein of unknown function (DUF777) AAA_13 PF13166.1 EPX75178.1 - 0.84 8.0 42.9 2.5 6.4 20.0 2.1 1 1 1 2 2 2 0 AAA domain ADIP PF11559.3 EPX75178.1 - 1.3 8.9 53.1 0.24 11.2 13.8 3.7 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EPX75178.1 - 5 6.6 69.5 9.1 5.8 22.7 3.2 1 1 2 3 3 3 0 IncA protein TPR_MLP1_2 PF07926.7 EPX75178.1 - 9.6 5.9 59.3 0.21 11.3 19.0 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Nop PF01798.13 EPX75179.1 - 4.2e-47 159.2 0.0 1e-46 157.9 0.0 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 EPX75179.1 - 3.8e-46 156.5 1.4 7.7e-46 155.5 1.0 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 EPX75179.1 - 6e-17 61.1 0.1 1.8e-16 59.6 0.1 1.9 1 0 0 1 1 1 1 NOSIC (NUC001) domain Glutaredoxin2_C PF04399.8 EPX75179.1 - 0.0095 15.5 0.1 0.029 13.9 0.1 1.8 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain Ribonuclease_3 PF00636.21 EPX75180.1 - 3.2e-19 69.4 0.3 1.3e-18 67.4 0.0 2.1 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EPX75180.1 - 2.4e-18 66.3 0.0 3.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EPX75180.1 - 3.9e-09 36.9 0.0 7.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Asn_synthase PF00733.16 EPX75181.1 - 2.7e-68 230.2 0.0 3.9e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EPX75181.1 - 7.2e-40 135.5 0.0 1.2e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EPX75181.1 - 1.7e-34 118.6 0.0 3.5e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EPX75181.1 - 2e-07 30.4 0.0 4.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EPX75181.1 - 0.0004 19.2 0.0 0.047 12.3 0.0 2.6 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EPX75181.1 - 0.03 13.2 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase ORMDL PF04061.9 EPX75182.1 - 1.1e-58 196.6 6.9 1.3e-58 196.4 4.8 1.1 1 0 0 1 1 1 1 ORMDL family Arm PF00514.18 EPX75182.1 - 0.053 13.3 0.1 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.20 EPX75183.1 - 8.8e-68 228.2 0.0 1.1e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX75183.1 - 1.3e-31 109.6 0.0 1.7e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPX75183.1 - 0.025 14.3 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EPX75183.1 - 0.16 10.9 0.0 0.33 9.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EPX75184.1 - 5.6e-23 81.4 0.0 1e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EPX75184.1 - 9.8e-12 43.9 6.9 0.18 11.9 0.1 5.7 5 0 0 5 5 5 4 HEAT repeat Pkinase_Tyr PF07714.12 EPX75184.1 - 9.7e-09 34.6 0.0 1.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EPX75184.1 - 1.1e-06 28.8 0.6 0.11 12.7 0.0 4.2 3 1 0 4 4 4 2 HEAT repeats BBS2_N PF14781.1 EPX75184.1 - 0.005 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, N-terminal APH PF01636.18 EPX75184.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family SCO1-SenC PF02630.9 EPX75185.1 - 2.6e-55 186.7 0.1 3.2e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 EPX75185.1 - 0.0012 18.8 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EPX75185.1 - 0.0015 18.2 0.0 0.0036 16.9 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family UQ_con PF00179.21 EPX75188.1 - 2.4e-52 176.0 0.0 2.7e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPX75188.1 - 8.6e-05 22.3 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPX75188.1 - 0.0031 17.3 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EPX75188.1 - 0.041 13.5 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain Rpn3_C PF08375.6 EPX75189.1 - 8.9e-25 86.8 2.5 8.9e-25 86.8 1.8 2.1 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EPX75189.1 - 3.5e-20 72.2 0.1 9.3e-18 64.4 0.0 3.0 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EPX75189.1 - 0.00016 21.4 0.1 0.0018 18.0 0.0 2.4 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 EPX75189.1 - 0.045 13.6 0.5 1.7 8.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat UDP-g_GGTase PF06427.6 EPX75190.1 - 7.2e-56 188.8 0.0 2.3e-55 187.1 0.0 1.9 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EPX75190.1 - 5.9e-07 29.0 0.9 5.9e-07 29.0 0.6 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 8 Far-17a_AIG1 PF04750.9 EPX75191.1 - 2.8e-42 144.1 16.7 3.1e-42 144.0 11.6 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Na_Ca_ex PF01699.19 EPX75191.1 - 4.9 6.7 9.5 60 3.2 6.6 2.4 1 1 0 1 1 1 0 Sodium/calcium exchanger protein Coatomer_WDAD PF04053.9 EPX75192.1 - 6.7e-135 450.3 7.8 6.7e-135 450.3 5.4 1.7 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 EPX75192.1 - 2.2e-77 260.3 0.0 3.6e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EPX75192.1 - 5.4e-56 184.6 15.4 4.1e-12 45.4 0.1 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EPX75192.1 - 0.0092 14.1 4.7 0.45 8.5 0.0 3.1 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Prok-RING_1 PF14446.1 EPX75192.1 - 0.068 12.9 2.3 0.14 11.8 1.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 M-factor PF03855.8 EPX75193.1 - 6.1e-07 29.3 3.5 7.4e-07 29.0 2.4 1.1 1 0 0 1 1 1 1 M-factor polyprenyl_synt PF00348.12 EPX75194.1 - 5.3e-51 172.9 0.0 7.6e-51 172.4 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase DUF4242 PF14026.1 EPX75194.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) AAA PF00004.24 EPX75195.1 - 1.6e-37 128.6 0.0 3.3e-37 127.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EPX75195.1 - 3e-09 36.6 0.0 1.3e-07 31.4 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EPX75195.1 - 1.4e-07 31.6 0.7 1.4e-05 25.2 0.2 2.9 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EPX75195.1 - 3e-06 26.4 0.0 4.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EPX75195.1 - 8.6e-05 22.5 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPX75195.1 - 0.00037 20.5 0.1 0.001 19.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EPX75195.1 - 0.00044 19.7 0.0 0.00078 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EPX75195.1 - 0.00064 18.5 0.1 0.0013 17.5 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 EPX75195.1 - 0.00089 18.9 0.1 0.0025 17.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EPX75195.1 - 0.0014 17.6 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EPX75195.1 - 0.0018 19.0 0.0 0.0033 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EPX75195.1 - 0.0024 17.4 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EPX75195.1 - 0.003 16.7 0.1 0.0061 15.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EPX75195.1 - 0.0039 17.0 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPX75195.1 - 0.0045 16.7 0.0 0.015 15.0 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EPX75195.1 - 0.0055 16.1 0.3 0.097 12.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EPX75195.1 - 0.0081 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPX75195.1 - 0.017 15.4 0.0 0.052 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EPX75195.1 - 0.021 14.5 0.1 0.11 12.1 0.0 2.1 1 1 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EPX75195.1 - 0.052 13.5 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EPX75195.1 - 0.071 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EPX75195.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 EPX75195.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 EPX75195.1 - 0.14 11.1 0.0 0.37 9.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EPX75195.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EPX75195.1 - 0.17 10.9 0.2 3.9 6.5 0.0 2.2 1 1 1 2 2 2 0 KaiC Adaptin_N PF01602.15 EPX75196.1 - 3.6e-140 467.7 16.5 4.7e-140 467.3 11.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EPX75196.1 - 3.1e-21 76.0 0.0 3.1e-21 76.0 0.0 3.6 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EPX75196.1 - 2.5e-14 53.3 0.1 2.1e-08 34.2 0.0 4.8 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.17 EPX75196.1 - 2.2e-09 36.5 0.3 0.016 15.2 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EPX75196.1 - 1.7e-06 28.3 0.3 0.035 14.6 0.0 4.6 5 0 0 5 5 5 2 HEAT-like repeat CLASP_N PF12348.3 EPX75196.1 - 0.0054 16.1 0.8 2.4 7.4 0.0 3.7 2 2 1 3 3 3 1 CLASP N terminal Arm PF00514.18 EPX75196.1 - 0.1 12.4 0.2 57 3.7 0.0 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SURF6 PF04935.7 EPX75197.1 - 4.7e-40 137.1 53.0 4.7e-40 137.1 36.7 1.8 1 1 1 2 2 2 1 Surfeit locus protein 6 Lentiviral_Tat PF02998.9 EPX75197.1 - 0.13 12.0 4.3 0.41 10.4 2.9 1.8 1 0 0 1 1 1 0 Lentiviral Tat protein HUN PF08729.5 EPX75198.1 - 3.4e-14 52.4 0.3 9.4e-14 51.0 0.2 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain zf-RING_2 PF13639.1 EPX75199.1 - 3.4e-11 42.7 6.4 9.1e-11 41.4 4.4 1.8 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPX75199.1 - 1.3e-09 38.0 1.6 2.4e-09 37.1 1.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPX75199.1 - 7.9e-07 28.6 4.4 1.6e-06 27.6 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPX75199.1 - 4.3e-06 26.6 3.3 4.3e-06 26.6 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPX75199.1 - 5.3e-06 26.0 8.1 2.4e-05 23.9 5.8 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPX75199.1 - 1.1e-05 24.9 8.4 0.0027 17.3 4.4 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPX75199.1 - 0.0054 16.5 7.2 0.016 15.0 5.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EPX75199.1 - 3 7.4 6.3 7.8 6.1 4.4 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit AAA PF00004.24 EPX75200.1 - 2.1e-06 27.9 0.0 4.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPX75200.1 - 0.061 13.4 0.0 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain RPAP1_C PF08620.5 EPX75202.1 - 9e-28 95.9 0.0 2e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EPX75202.1 - 8e-10 38.1 5.8 1.6e-09 37.1 4.0 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal HEAT PF02985.17 EPX75202.1 - 0.094 12.8 0.6 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 HEAT repeat Pyr_redox_2 PF07992.9 EPX75204.1 - 2.8e-22 79.5 0.0 2.8e-13 50.2 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPX75204.1 - 1.2e-10 41.6 0.0 1.2e-08 35.1 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPX75204.1 - 0.0036 17.3 0.3 0.23 11.4 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TraB PF01963.12 EPX75204.1 - 0.034 13.5 0.0 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 TraB family RNase_PH PF01138.16 EPX75205.1 - 2.4e-21 76.4 0.3 4e-21 75.7 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Rsbr_N PF08678.5 EPX75205.1 - 0.003 17.4 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 Rsbr N terminal PapB PF03333.8 EPX75205.1 - 0.0033 17.1 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 Adhesin biosynthesis transcription regulatory protein AFG1_ATPase PF03969.11 EPX75206.1 - 5.8e-87 291.8 0.0 1.5e-81 274.0 0.0 2.9 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EPX75206.1 - 9e-06 25.7 0.0 0.00048 20.1 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain Bac_DnaA PF00308.13 EPX75206.1 - 0.00017 21.3 0.2 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.1 EPX75206.1 - 0.0013 18.8 0.0 0.0051 16.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EPX75206.1 - 0.0017 18.5 0.0 0.0045 17.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EPX75206.1 - 0.0023 17.7 0.1 0.043 13.5 0.0 2.4 2 1 1 3 3 3 1 Archaeal ATPase AAA_14 PF13173.1 EPX75206.1 - 0.0079 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPX75206.1 - 0.0082 16.2 0.0 0.12 12.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase FKBP_C PF00254.23 EPX75207.1 - 6.7e-32 109.3 0.0 7.8e-32 109.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FTHFS PF01268.14 EPX75208.1 - 1e-257 855.6 0.1 1.7e-257 854.9 0.0 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EPX75208.1 - 2.3e-67 225.0 1.1 5.6e-67 223.8 0.7 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EPX75208.1 - 2.3e-39 134.0 0.1 6.9e-39 132.5 0.0 1.9 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 EPX75209.1 - 4.1e-57 192.6 0.0 7.4e-57 191.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPX75209.1 - 3.2e-36 123.4 0.0 8.7e-36 122.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPX75209.1 - 3.8e-16 58.9 1.1 1.1e-15 57.4 0.7 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EPX75209.1 - 6.9e-05 22.4 0.3 0.00022 20.8 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EPX75209.1 - 0.0014 18.5 0.5 0.0043 16.9 0.4 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Methyltransf_31 PF13847.1 EPX75210.1 - 2e-22 79.3 0.0 2.6e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX75210.1 - 2.8e-17 63.3 0.0 4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX75210.1 - 2.2e-10 40.9 0.0 3.7e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPX75210.1 - 2e-09 37.4 0.0 3.9e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPX75210.1 - 2.3e-09 37.1 0.0 3.1e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX75210.1 - 4.1e-07 30.3 0.0 9.1e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EPX75210.1 - 1.1e-06 28.3 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX75210.1 - 1.2e-06 28.7 0.0 2.1e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPX75210.1 - 1.2e-05 24.7 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_20 PF12147.3 EPX75210.1 - 0.00038 19.4 0.0 0.00048 19.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EPX75210.1 - 0.0011 18.1 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EPX75210.1 - 0.0024 16.9 0.0 0.0048 15.9 0.0 1.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.4 EPX75210.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EPX75210.1 - 0.039 13.0 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EPX75210.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ribosomal_L13 PF00572.13 EPX75211.1 - 2.2e-26 92.4 0.1 5.6e-26 91.1 0.0 1.7 3 0 0 3 3 3 1 Ribosomal protein L13 RNA_pol_3_Rpc31 PF11705.3 EPX75212.1 - 1e-40 140.1 9.4 1.2e-40 139.9 6.5 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF916 PF06030.7 EPX75212.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) TT_ORF2 PF02957.10 EPX75212.1 - 0.14 12.8 5.2 0.28 11.8 3.6 1.4 1 0 0 1 1 1 0 TT viral ORF2 UAA PF08449.6 EPX75213.1 - 9.7e-86 287.4 18.7 1.1e-85 287.2 13.0 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPX75213.1 - 1.1e-10 41.6 9.8 1.1e-10 41.6 6.8 3.2 2 1 2 4 4 4 1 EamA-like transporter family EmrE PF13536.1 EPX75213.1 - 6.9e-07 29.4 18.6 0.00024 21.2 3.5 3.0 2 1 1 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EPX75213.1 - 8.3e-07 28.7 8.9 8.3e-07 28.7 6.2 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EPX75213.1 - 2.6e-05 23.4 5.7 0.0053 15.8 0.3 2.2 1 1 1 2 2 2 2 Nucleotide-sugar transporter IspA PF04279.10 EPX75213.1 - 0.45 10.4 9.7 0.82 9.6 0.4 2.3 2 0 0 2 2 2 0 Intracellular septation protein A PWI PF01480.12 EPX75214.1 - 1.2e-09 38.1 0.2 3.6e-09 36.6 0.1 1.8 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EPX75214.1 - 0.0035 16.9 0.0 0.0085 15.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S21 PF01165.15 EPX75215.1 - 2.6e-16 58.7 3.3 2.6e-16 58.7 2.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S21 PigN PF04987.9 EPX75216.1 - 1.5e-120 402.8 42.4 1.9e-120 402.5 29.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EPX75216.1 - 2.5e-08 33.6 0.1 1.7e-05 24.3 0.1 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EPX75216.1 - 3.8e-05 23.0 0.2 6.1e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EPX75216.1 - 0.00018 21.0 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Rhodanese PF00581.15 EPX75217.1 - 2.5e-16 60.0 0.1 1.1e-15 57.9 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain Alpha_E1_glycop PF01589.11 EPX75217.1 - 0.028 12.7 0.0 0.032 12.5 0.0 1.0 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein E1-E2_ATPase PF00122.15 EPX75218.1 - 1.6e-61 207.3 3.3 1.6e-61 207.3 2.3 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPX75218.1 - 2.3e-33 115.2 7.4 2.3e-33 115.2 5.1 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPX75218.1 - 1.3e-28 100.8 0.0 8.8e-28 98.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPX75218.1 - 6.8e-21 74.0 0.0 1.4e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EPX75218.1 - 3e-17 61.8 1.1 5.7e-17 60.9 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EPX75218.1 - 2e-14 54.1 0.0 5.4e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPX75218.1 - 1.8e-05 24.4 0.7 0.00044 19.9 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_S17e PF00833.13 EPX75220.1 - 2e-60 201.9 0.5 2.2e-60 201.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_L2_C PF03947.13 EPX75221.1 - 1.1e-37 128.7 3.9 1.2e-37 128.6 2.1 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPX75221.1 - 2.5e-15 56.1 0.0 5.4e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cullin_binding PF03556.10 EPX75222.1 - 2.8e-26 91.9 1.0 2.8e-26 91.9 0.7 1.7 2 1 0 2 2 2 1 Cullin binding Arrestin_C PF02752.17 EPX75223.1 - 1.6e-14 54.2 0.0 3.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EPX75223.1 - 3.2e-09 36.7 0.0 1.1e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Dynamin_N PF00350.18 EPX75224.1 - 8.4e-16 58.2 1.6 4.3e-15 55.9 0.0 3.0 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 EPX75224.1 - 3e-10 39.8 0.8 1.3e-09 37.7 0.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPX75224.1 - 1.4e-09 37.9 0.0 6.8e-09 35.7 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EPX75224.1 - 0.00027 20.4 0.0 0.74 9.2 0.0 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EPX75224.1 - 0.002 17.5 0.5 0.013 14.9 0.4 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EPX75224.1 - 0.0033 17.9 0.0 1.7 9.1 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EPX75224.1 - 0.0036 17.5 0.5 0.29 11.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EPX75224.1 - 0.0038 16.7 0.0 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.13 EPX75224.1 - 0.008 15.4 0.3 2.3 7.5 0.1 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_22 PF13401.1 EPX75224.1 - 0.05 13.7 0.0 8.1 6.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain SH3_1 PF00018.23 EPX75225.1 - 3.2e-06 26.4 0.0 8.7e-06 25.0 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPX75225.1 - 3e-05 23.5 0.1 7.9e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain DAO PF01266.19 EPX75226.1 - 5.4e-47 160.4 0.0 6.4e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPX75226.1 - 5.5e-07 28.7 0.0 0.0035 16.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EPX75226.1 - 2.5e-06 27.5 0.1 0.0023 17.8 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPX75226.1 - 3.9e-06 26.7 0.0 1.1e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPX75226.1 - 0.00014 21.0 0.2 0.00033 19.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EPX75226.1 - 0.00043 20.6 0.3 0.016 15.5 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPX75226.1 - 0.00049 19.2 0.1 0.00077 18.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EPX75226.1 - 0.00065 18.6 0.3 0.053 12.3 0.0 2.4 2 1 1 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EPX75226.1 - 0.00074 19.3 0.4 0.55 9.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPX75226.1 - 0.0026 17.8 0.0 0.025 14.6 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPX75226.1 - 0.0037 15.7 0.1 1.6 7.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 EPX75226.1 - 0.017 14.0 0.1 0.086 11.7 0.0 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EPX75226.1 - 0.024 13.2 0.1 0.41 9.2 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Saccharop_dh PF03435.13 EPX75226.1 - 0.064 12.2 0.1 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 EPX75226.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 EPX75226.1 - 0.14 12.2 0.0 0.68 10.0 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Arm PF00514.18 EPX75227.1 - 8.7e-70 228.4 29.8 9.3e-09 34.7 0.3 11.8 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EPX75227.1 - 1.8e-20 72.9 15.5 0.0001 22.4 0.3 7.9 1 1 5 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 EPX75227.1 - 9.3e-11 41.8 22.0 0.038 14.5 0.1 9.2 6 4 5 11 11 11 4 HEAT-like repeat HEAT PF02985.17 EPX75227.1 - 3.8e-10 38.9 17.0 0.73 10.0 0.0 9.7 10 0 0 10 10 10 3 HEAT repeat Arm_2 PF04826.8 EPX75227.1 - 1.6e-08 33.9 11.3 0.0012 18.0 0.2 3.5 2 1 1 3 3 3 3 Armadillo-like KAP PF05804.7 EPX75227.1 - 8.8e-08 30.5 2.5 1.2e-07 30.0 1.7 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Adaptin_N PF01602.15 EPX75227.1 - 7.3e-07 27.8 15.6 0.00018 20.0 0.9 2.4 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.9 EPX75227.1 - 1.3e-06 27.7 11.2 0.0025 17.0 3.9 3.9 1 1 2 3 3 3 2 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 EPX75227.1 - 0.011 16.0 1.8 4.2 7.8 0.0 3.6 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 EPX75227.1 - 0.63 10.6 13.2 16 6.3 0.2 6.9 8 0 0 8 8 8 0 PBS lyase HEAT-like repeat RhoGAP PF00620.22 EPX75228.1 - 7.9e-17 61.2 0.0 1.7e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Gp_dh_C PF02800.15 EPX75229.1 - 1.3e-73 245.6 0.0 2e-73 245.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EPX75229.1 - 2.8e-60 202.6 0.2 4.3e-60 202.0 0.2 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EPX75229.1 - 0.0074 15.8 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EPX75229.1 - 0.024 14.5 0.5 0.1 12.5 0.3 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2436 PF10365.4 EPX75229.1 - 0.034 13.7 0.3 0.069 12.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) 2-Hacid_dh_C PF02826.14 EPX75229.1 - 0.08 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PVL_ORF50 PF07768.6 EPX75230.1 - 0.23 11.4 6.1 0.31 11.0 4.2 1.1 1 0 0 1 1 1 0 PVL ORF-50-like family DUF3566 PF12089.3 EPX75230.1 - 0.24 11.4 1.2 0.37 10.8 0.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) BLVR PF06375.6 EPX75230.1 - 0.67 9.7 6.9 0.89 9.3 4.8 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) CUE PF02845.11 EPX75231.1 - 3.7e-09 35.8 0.0 9.5e-09 34.5 0.0 1.7 2 0 0 2 2 2 1 CUE domain DUF1837 PF08878.6 EPX75233.1 - 0.0095 15.5 2.6 1.7 8.1 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF1837) Spidroin_MaSp PF11260.3 EPX75233.1 - 5.4 7.1 7.6 9.6 6.3 1.3 2.4 1 1 1 2 2 2 0 Major ampullate spidroin 1 and 2 FAD_binding_8 PF08022.7 EPX75234.1 - 1.5e-27 95.4 0.0 4.5e-27 93.9 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EPX75234.1 - 1.7e-18 67.0 0.1 1.9e-17 63.5 0.1 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPX75234.1 - 4e-12 46.3 6.6 4e-12 46.3 4.6 2.6 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EPX75234.1 - 0.0039 17.7 0.0 0.012 16.2 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4083 PF13314.1 EPX75234.1 - 0.031 14.0 0.1 0.031 14.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Methyltransf_3 PF01596.12 EPX75235.1 - 5.3e-15 55.0 0.0 7e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EPX75235.1 - 4.5e-13 49.9 0.0 2e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPX75235.1 - 3.2e-07 30.9 0.0 6.3e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPX75235.1 - 0.00042 20.3 0.0 0.00055 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EPX75235.1 - 0.0048 16.2 0.0 0.047 13.0 0.0 2.0 1 1 1 2 2 2 1 Cephalosporin hydroxylase DUF4345 PF14248.1 EPX75236.1 - 1 8.7 9.1 0.038 13.4 1.0 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4345) 7TM_GPCR_Srj PF10319.4 EPX75236.1 - 1.2 8.1 9.6 1.7 7.6 6.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srj DUF3671 PF12420.3 EPX75236.1 - 1.6 8.7 8.6 1 9.3 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function Malic_M PF03949.10 EPX75237.1 - 1.2e-83 280.6 0.0 1.7e-83 280.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EPX75237.1 - 4e-59 199.2 0.0 5.9e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MUG113 PF13455.1 EPX75238.1 - 2e-11 44.1 0.1 4.8e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EPX75238.1 - 4.8e-10 39.7 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain DUF866 PF05907.8 EPX75238.1 - 0.083 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) GSH_synth_ATP PF03917.12 EPX75239.1 - 1.1e-130 435.5 0.1 1.3e-130 435.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EPX75239.1 - 5e-33 113.3 0.1 1.1e-32 112.2 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase tRNA-synt_2b PF00587.20 EPX75240.1 - 2.5e-65 219.2 0.3 4.7e-65 218.3 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPX75240.1 - 1.1e-22 79.7 0.3 3.5e-22 78.1 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain TrkH PF02386.11 EPX75241.1 - 2.4e-120 401.3 19.7 1.7e-117 391.9 10.5 2.1 2 0 0 2 2 2 2 Cation transport protein MCM PF00493.18 EPX75242.1 - 1.6e-141 470.9 0.7 2.1e-141 470.5 0.5 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPX75242.1 - 9.5e-22 77.7 0.3 3.1e-21 76.1 0.2 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPX75242.1 - 3e-06 26.5 0.0 0.00038 19.6 0.0 2.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPX75242.1 - 3.2e-05 23.6 0.0 7.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPX75242.1 - 0.0032 17.0 0.1 0.018 14.6 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPX75242.1 - 0.02 14.3 0.0 0.23 10.9 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain COX5A PF02284.11 EPX75243.1 - 2.1e-34 117.7 0.0 2.4e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Cas_Cas02710 PF09670.5 EPX75243.1 - 0.043 12.4 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) ELO PF01151.13 EPX75245.1 - 5.8e-60 202.6 24.3 7.1e-60 202.3 16.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Mito_carr PF00153.22 EPX75246.1 - 5.9e-15 54.7 0.2 0.00058 19.5 0.0 4.3 4 1 0 4 4 4 4 Mitochondrial carrier protein Ring_hydroxyl_A PF00848.14 EPX75246.1 - 0.047 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) CRM1_C PF08767.6 EPX75247.1 - 5.5e-127 423.0 5.6 5.5e-127 423.0 3.9 2.8 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EPX75247.1 - 2.7e-42 144.1 6.1 2.7e-42 144.1 4.3 4.6 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 EPX75247.1 - 8e-12 44.9 0.4 5.6e-11 42.1 0.3 2.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain Virul_fac_BrkB PF03631.10 EPX75247.1 - 0.015 14.6 0.2 0.038 13.3 0.1 1.6 1 0 0 1 1 1 0 Virulence factor BrkB PNP_UDP_1 PF01048.15 EPX75248.1 - 1.9e-47 161.2 0.4 2.3e-47 160.9 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily HECT PF00632.20 EPX75249.1 - 6.3e-90 301.5 0.1 9.5e-90 300.9 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EPX75249.1 - 2.1e-09 37.0 5.5 3.5e-08 33.1 0.7 2.8 2 0 0 2 2 2 2 WW domain DUF600 PF04634.7 EPX75250.1 - 0.057 13.4 4.0 1.1 9.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF600 Utp11 PF03998.8 EPX75250.1 - 2.1 8.0 12.2 0.26 11.1 5.1 1.9 2 0 0 2 2 2 0 Utp11 protein Ribosomal_L14e PF01929.12 EPX75251.1 - 3.7e-28 97.6 0.8 5.2e-28 97.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EPX75251.1 - 4.3e-05 23.0 2.5 9.7e-05 21.9 1.7 1.6 1 0 0 1 1 1 1 KOW motif DUF3363 PF11843.3 EPX75251.1 - 0.018 13.7 0.1 0.023 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) Nitr_red_assoc PF09655.5 EPX75251.1 - 0.043 14.1 0.6 0.062 13.6 0.4 1.3 1 1 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) ubiquitin PF00240.18 EPX75252.1 - 1.3e-34 117.4 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EPX75252.1 - 1.2e-29 101.6 11.4 1.8e-29 101.0 7.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EPX75252.1 - 4.8e-20 71.0 0.7 6.5e-20 70.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPX75252.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPX75252.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EPX75252.1 - 0.0047 16.7 0.1 0.01 15.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPX75252.1 - 0.0089 16.1 0.1 0.01 16.0 0.1 1.2 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EPX75252.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EPX75252.1 - 0.17 10.1 0.5 4.3 5.5 0.2 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Fer2_3 PF13085.1 EPX75252.1 - 0.28 11.0 2.0 1.3 8.8 1.4 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-DHHC PF01529.15 EPX75252.1 - 0.71 9.2 4.7 1.1 8.6 3.2 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ribosomal_S26e PF01283.14 EPX75253.1 - 5.9e-52 174.7 8.6 6.7e-52 174.5 6.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf-ribbon_3 PF13248.1 EPX75253.1 - 0.68 9.2 2.7 2.2 7.6 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Formyl_trans_N PF00551.14 EPX75255.1 - 3.6e-20 72.2 0.0 8.9e-20 70.9 0.0 1.6 2 0 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.13 EPX75255.1 - 4.4e-11 42.7 0.0 7.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Alba PF01918.16 EPX75256.1 - 2.5e-06 26.9 0.1 3.5e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Alba Membr_traf_MHD PF10540.4 EPX75256.1 - 0.073 12.8 0.5 0.11 12.3 0.3 1.5 1 1 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain Tctex-1 PF03645.8 EPX75257.1 - 8e-23 80.2 0.3 8.9e-23 80.0 0.2 1.0 1 0 0 1 1 1 1 Tctex-1 family DASH_Dad2 PF08654.5 EPX75258.1 - 1.9e-20 72.7 0.4 2.2e-20 72.5 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 CENP-F_leu_zip PF10473.4 EPX75258.1 - 0.024 14.5 1.1 0.029 14.2 0.7 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 EPX75258.1 - 0.045 13.0 0.4 0.054 12.8 0.3 1.2 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DASH_Duo1 PF08651.5 EPX75258.1 - 0.07 12.7 0.2 0.1 12.2 0.1 1.3 1 1 0 1 1 1 0 DASH complex subunit Duo1 PORR PF11955.3 EPX75258.1 - 0.11 11.1 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Plant organelle RNA recognition domain ALAD PF00490.16 EPX75259.1 - 6.2e-118 393.3 0.0 6.9e-118 393.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Pkinase PF00069.20 EPX75260.1 - 3.9e-32 111.4 0.0 5.4e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX75260.1 - 1.9e-09 36.9 0.0 2.5e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Nucleoporin_C PF03177.9 EPX75261.1 - 2.7e-74 250.7 15.2 4.2e-74 250.1 9.9 1.7 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EPX75261.1 - 3.4e-26 91.9 0.7 9e-26 90.5 0.2 1.8 2 0 0 2 2 2 1 Nup133 N terminal like Fip1 PF05182.8 EPX75261.1 - 0.79 9.0 3.2 1.3 8.3 1.1 2.2 2 0 0 2 2 2 0 Fip1 motif TRM13 PF05206.9 EPX75262.1 - 2.5e-68 230.1 0.2 3.2e-68 229.7 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.7 EPX75262.1 - 6.3e-09 35.3 3.6 6.3e-09 35.3 2.5 1.9 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 EPX75262.1 - 3.8e-05 23.3 1.0 0.00018 21.1 0.7 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPX75262.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ETF PF01012.16 EPX75263.1 - 5.9e-33 113.8 0.3 8.1e-33 113.4 0.2 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Pkinase PF00069.20 EPX75264.1 - 7.2e-59 199.0 0.0 1e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPX75264.1 - 3.2e-26 91.9 0.0 4.8e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPX75264.1 - 1.2e-08 34.2 0.0 1.8e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPX75264.1 - 0.00034 19.7 0.0 0.00061 18.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPX75264.1 - 0.057 13.1 0.0 0.74 9.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rif1_N PF12231.3 EPX75265.1 - 1.1e-93 314.1 1.4 2.4e-93 313.0 0.9 1.6 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Pardaxin PF07425.6 EPX75266.1 - 0.013 14.8 0.8 0.027 13.8 0.5 1.4 1 0 0 1 1 1 0 Pardaxin PhoQ_Sensor PF08918.5 EPX75267.1 - 0.14 11.6 0.9 0.24 10.8 0.6 1.3 1 0 0 1 1 1 0 PhoQ Sensor Ras PF00071.17 EPX75268.1 - 8.3e-60 200.8 0.0 9.6e-60 200.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPX75268.1 - 8e-20 71.5 0.1 2.6e-19 69.8 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPX75268.1 - 1.9e-13 50.0 0.0 2.4e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPX75268.1 - 9.6e-07 28.4 0.0 2.2e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPX75268.1 - 7.2e-06 25.3 0.0 9e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPX75268.1 - 4e-05 23.5 0.0 7.7e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EPX75268.1 - 0.0051 16.2 0.1 0.031 13.7 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EPX75268.1 - 0.024 13.7 0.5 0.071 12.2 0.0 1.9 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPX75268.1 - 0.045 13.7 0.1 0.076 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF4187 PF13821.1 EPX75269.1 - 3.1e-17 61.8 4.2 3.1e-17 61.8 2.9 2.6 3 1 0 3 3 3 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EPX75269.1 - 7.5e-09 35.2 2.4 1.3e-08 34.4 1.7 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EPX75269.1 - 0.0018 18.0 1.7 0.0056 16.5 1.2 2.0 1 1 0 1 1 1 1 DExH-box splicing factor binding site DUF726 PF05277.7 EPX75270.1 - 2.2e-129 431.3 0.4 2.8e-129 430.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EPX75270.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF438 PF04282.8 EPX75270.1 - 0.055 13.2 1.8 0.16 11.8 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF438) PX PF00787.19 EPX75271.1 - 2.7e-22 78.6 0.4 6.3e-22 77.5 0.2 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EPX75271.1 - 7.7e-06 25.3 17.3 0.00061 19.1 1.7 2.2 1 1 0 2 2 2 2 Vps5 C terminal like Ribosomal_L50 PF10501.4 EPX75271.1 - 0.22 11.4 4.2 0.68 9.9 1.3 2.6 2 1 0 2 2 2 0 Ribosomal subunit 39S IncA PF04156.9 EPX75271.1 - 0.43 10.1 20.5 3.4 7.2 9.4 2.6 2 1 0 2 2 2 0 IncA protein BLOC1_2 PF10046.4 EPX75271.1 - 0.89 9.7 11.9 12 6.1 1.7 3.6 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 EPX75271.1 - 2.2 7.3 7.0 1.4 8.0 1.1 2.4 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Phos_pyr_kin PF08543.7 EPX75272.1 - 1.5e-15 57.0 0.0 2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EPX75272.1 - 4.4e-08 32.5 0.0 2.6e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase P34-Arc PF04045.9 EPX75273.1 - 4.9e-100 333.7 1.4 7.3e-100 333.2 1.0 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc NuA4 PF09340.5 EPX75274.1 - 1.5e-25 88.5 0.3 1.5e-25 88.5 0.2 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Syntaxin-6_N PF09177.6 EPX75274.1 - 0.97 9.8 3.8 3.5 8.1 0.1 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal RabGAP-TBC PF00566.13 EPX75275.1 - 9.2e-39 133.1 0.0 1.2e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ribosomal_S13_N PF08069.7 EPX75276.1 - 3.2e-28 97.3 0.2 7.3e-28 96.1 0.2 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EPX75276.1 - 3.8e-24 84.2 0.1 5.6e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Rax2 PF12768.2 EPX75277.1 - 1.8e-30 106.0 1.0 1.8e-30 106.0 0.7 4.6 6 0 0 6 6 6 2 Cortical protein marker for cell polarity DAD PF02109.11 EPX75278.1 - 1.5e-40 137.7 2.6 1.8e-40 137.4 1.8 1.0 1 0 0 1 1 1 1 DAD family PalH PF08733.5 EPX75278.1 - 0.0043 15.9 0.3 0.0051 15.6 0.2 1.1 1 0 0 1 1 1 1 PalH/RIM21 MFS_1 PF07690.11 EPX75279.1 - 3.1e-07 29.4 28.8 3.3e-07 29.3 19.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EPX75279.1 - 4.5e-07 29.4 7.2 1.7e-06 27.6 5.0 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Cytochrom_B_N PF00033.14 EPX75279.1 - 0.0084 15.4 3.2 0.0084 15.4 2.2 2.4 2 1 1 3 3 3 1 Cytochrome b(N-terminal)/b6/petB NGP1NT PF08153.7 EPX75280.1 - 7.7e-50 168.1 0.3 1.3e-49 167.5 0.2 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EPX75280.1 - 8.2e-19 67.6 0.1 2.3e-15 56.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EPX75280.1 - 3.4e-06 26.4 0.1 6.2e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 EPX75280.1 - 8.5e-05 21.8 0.1 0.025 13.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPX75280.1 - 0.00024 20.5 0.1 0.092 12.1 0.0 3.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EPX75280.1 - 0.00071 19.4 3.3 0.11 12.3 0.0 3.8 3 2 1 4 4 4 1 Dynamin family DUF258 PF03193.11 EPX75280.1 - 0.0016 17.6 0.0 0.004 16.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EPX75280.1 - 0.053 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.14 EPX75280.1 - 0.083 12.3 0.1 9.2 5.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EPX75280.1 - 0.11 13.0 0.2 6.2 7.3 0.0 2.8 3 0 0 3 3 3 0 Miro-like protein LRR_8 PF13855.1 EPX75281.1 - 0.011 15.4 2.7 0.073 12.8 0.1 3.3 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.2 EPX75281.1 - 0.071 12.8 0.0 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 F-box-like LRR_5 PF13306.1 EPX75281.1 - 0.12 12.0 3.9 0.16 11.6 0.1 2.7 2 2 0 2 2 2 0 Leucine rich repeats (6 copies) LRR_4 PF12799.2 EPX75281.1 - 0.29 10.8 4.3 17 5.1 0.1 4.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Ion_trans PF00520.26 EPX75282.1 - 3.2e-107 356.2 107.4 9.1e-37 126.2 9.5 5.6 5 1 0 5 5 5 4 Ion transport protein 4HBT PF03061.17 EPX75284.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily V-ATPase_C PF03223.10 EPX75285.1 - 6.1e-111 370.9 8.0 6.8e-111 370.7 5.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Med11 PF10280.4 EPX75285.1 - 3.2 7.8 7.2 1 9.4 1.7 2.5 3 0 0 3 3 3 0 Mediator complex protein E1-E2_ATPase PF00122.15 EPX75286.1 - 1.1e-56 191.3 4.2 1.1e-56 191.3 2.9 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPX75286.1 - 9.9e-44 149.0 9.1 9.9e-44 149.0 6.3 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPX75286.1 - 8.3e-25 88.4 0.0 3.2e-24 86.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPX75286.1 - 3.3e-14 52.5 0.1 7e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPX75286.1 - 1.1e-11 45.2 0.0 5.9e-11 42.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPX75286.1 - 6.5e-08 31.9 0.0 4.1e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPX75286.1 - 6.8e-05 22.5 0.2 0.00021 20.9 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cyclin_N PF00134.18 EPX75287.1 - 9.9e-43 144.7 1.0 4.5e-41 139.3 0.5 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPX75287.1 - 7.2e-27 93.6 0.0 1.6e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Glutaredoxin PF00462.19 EPX75288.1 - 6.7e-16 58.0 0.0 1.1e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Zip PF02535.17 EPX75289.1 - 3.7e-47 160.8 7.4 4.6e-46 157.2 5.1 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Podoplanin PF05808.6 EPX75289.1 - 0.83 9.1 4.5 2.6 7.5 2.7 2.2 3 0 0 3 3 3 0 Podoplanin FtsX PF02687.16 EPX75289.1 - 6 6.6 12.6 19 5.0 5.5 2.9 2 1 0 2 2 2 0 FtsX-like permease family HSP9_HSP12 PF04119.7 EPX75290.1 - 3.2e-25 87.9 9.5 3.7e-25 87.7 6.6 1.1 1 0 0 1 1 1 1 Heat shock protein 9/12 Glyco_hydro_32C PF08244.7 EPX75290.1 - 0.016 15.5 1.2 0.028 14.7 0.7 1.5 1 1 1 2 2 2 0 Glycosyl hydrolases family 32 C terminal MT0933_antitox PF14013.1 EPX75290.1 - 0.11 12.5 4.1 7.5 6.7 2.8 2.3 1 1 0 1 1 1 0 MT0933-like antitoxin protein YtxH PF12732.2 EPX75290.1 - 0.81 10.0 4.2 1.3 9.3 2.9 1.5 1 1 0 1 1 1 0 YtxH-like protein GTP_EFTU PF00009.22 EPX75291.1 - 2.8e-06 26.8 0.0 0.00049 19.5 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF2894 PF11445.3 EPX75291.1 - 5.9 7.1 15.1 0.59 10.3 7.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) zf-CCCH PF00642.19 EPX75292.1 - 6.3e-12 44.8 16.1 4.2e-07 29.4 1.1 3.4 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EPX75292.1 - 9.3e-08 31.8 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPX75292.1 - 2.1e-06 27.2 0.1 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX75292.1 - 0.023 14.6 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 EPX75292.1 - 0.15 12.0 1.5 14 5.7 0.1 2.5 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) DAHP_synth_1 PF00793.15 EPX75293.1 - 8.1e-91 303.4 0.0 9.8e-91 303.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family EF-hand_7 PF13499.1 EPX75294.1 - 2e-12 47.0 0.0 6e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPX75294.1 - 1.9e-11 42.8 0.0 0.00041 20.0 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EPX75294.1 - 1.1e-10 40.0 0.1 0.0013 17.8 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 EPX75294.1 - 9e-08 31.9 0.0 0.00048 19.9 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EPX75294.1 - 0.00025 20.6 1.5 0.0052 16.3 0.1 3.2 2 2 2 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.1 EPX75294.1 - 0.011 15.0 0.1 0.62 9.5 0.0 3.1 3 1 0 3 3 3 0 EF hand HEAT PF02985.17 EPX75295.1 - 1.7e-44 145.9 22.3 0.00055 19.8 0.0 13.9 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 EPX75295.1 - 1.4e-34 118.1 1.4 2.1e-09 37.5 0.0 6.9 3 2 3 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 EPX75295.1 - 6.7e-13 48.7 14.5 1.4 9.5 0.4 9.7 7 3 4 11 11 11 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPX75295.1 - 7.7e-13 48.6 1.7 0.091 13.1 0.0 7.2 3 2 5 8 8 8 4 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EPX75295.1 - 3e-07 29.1 2.5 1.8e-06 26.5 0.4 2.8 1 1 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.2 EPX75295.1 - 0.0049 16.7 7.8 0.36 10.6 0.0 5.1 2 1 3 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF2454 PF10521.4 EPX75295.1 - 0.035 13.0 1.3 5.1 6.0 0.0 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF2454) DUF2435 PF10363.4 EPX75295.1 - 0.063 13.1 3.1 2.1 8.3 0.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2435) M11L PF11099.3 EPX75295.1 - 0.09 12.5 0.1 6.8 6.3 0.0 3.3 2 1 1 3 3 3 0 Apoptosis regulator M11L like Arm PF00514.18 EPX75295.1 - 0.54 10.1 14.0 5.8 6.9 0.0 7.0 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat PRELI PF04707.9 EPX75296.1 - 3.4e-45 153.4 0.0 4.3e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family ScpA_ScpB PF02616.9 EPX75296.1 - 0.073 12.6 0.2 0.097 12.2 0.1 1.1 1 0 0 1 1 1 0 ScpA/B protein GTP1_OBG PF01018.17 EPX75297.1 - 2e-36 125.0 3.3 1.1e-25 90.0 0.8 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EPX75297.1 - 5.6e-23 81.1 0.0 9.9e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPX75297.1 - 1.2e-10 40.8 0.0 5.7e-10 38.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 EPX75297.1 - 6.6e-06 25.4 0.1 2e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPX75297.1 - 0.00025 20.5 0.2 0.24 10.7 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Ras PF00071.17 EPX75297.1 - 0.0014 18.0 0.0 0.0061 15.9 0.0 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EPX75297.1 - 0.0089 16.5 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 EPX75297.1 - 0.017 14.5 0.2 4.5 6.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EPX75297.1 - 0.019 14.8 0.0 0.22 11.2 0.0 2.3 2 1 0 2 2 2 0 Dynamin family ArgK PF03308.11 EPX75297.1 - 0.028 13.1 0.0 0.24 10.1 0.0 2.1 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 EPX75297.1 - 0.033 14.4 0.2 0.096 12.9 0.1 1.9 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 EPX75297.1 - 0.091 11.9 0.0 0.19 10.9 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EPX75297.1 - 0.16 11.4 0.1 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Peptidase_S8 PF00082.17 EPX75298.1 - 9.1e-52 175.9 0.2 1.4e-51 175.3 0.1 1.3 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.3 EPX75298.1 - 2.4e-49 167.2 0.3 4.7e-49 166.3 0.2 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II Vac_ImportDeg PF09783.4 EPX75299.1 - 5e-39 133.6 0.0 7.5e-39 133.0 0.0 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein SLS PF14611.1 EPX75300.1 - 1.4e-17 63.8 1.4 2.1e-17 63.2 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Sec7 PF01369.15 EPX75301.1 - 3.7e-68 228.9 0.6 1.2e-67 227.2 0.4 2.0 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EPX75301.1 - 2.2e-53 180.1 5.4 2.2e-53 180.1 3.7 4.6 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EPX75301.1 - 3.9e-27 93.5 0.3 3.9e-27 93.5 0.2 5.6 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) GDPD PF03009.12 EPX75302.1 - 2.4e-37 128.8 0.0 3.4e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EPX75302.1 - 0.0025 17.9 2.1 0.63 10.2 0.5 3.2 3 1 0 3 3 3 2 Glycerophosphoryl diester phosphodiesterase family CRAL_TRIO_2 PF13716.1 EPX75302.1 - 0.066 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain WD40 PF00400.27 EPX75303.1 - 1.1e-52 174.0 17.4 6.2e-12 44.9 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EPX75303.1 - 9.9e-09 33.8 11.9 0.013 13.6 0.3 5.8 2 2 2 4 4 4 3 Nucleoporin Nup120/160 F-box-like PF12937.2 EPX75303.1 - 2.7e-06 27.0 0.2 1.3e-05 24.8 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPX75303.1 - 1.2e-05 24.7 0.1 3.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EPX75303.1 - 2.6e-05 23.8 0.0 0.026 13.9 0.1 2.6 3 0 0 3 3 3 2 PQQ-like domain Ricin_B_lectin PF00652.17 EPX75303.1 - 0.03 14.3 0.1 0.081 12.9 0.0 1.7 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Birna_VP4 PF01768.11 EPX75304.1 - 0.0025 16.8 0.0 0.0026 16.8 0.0 1.0 1 0 0 1 1 1 1 Birnavirus VP4 protein Prenyltransf PF01255.14 EPX75305.1 - 5.2e-82 274.3 0.1 6e-82 274.0 0.1 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase WD40 PF00400.27 EPX75306.1 - 8.6e-36 120.5 0.5 5.7e-10 38.6 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EPX75306.1 - 0.0045 16.4 0.3 0.94 8.8 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain NAD_binding_7 PF13241.1 EPX75307.1 - 2.9e-28 98.1 0.0 4.3e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EPX75307.1 - 2.9e-21 74.5 0.0 4.9e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EPX75307.1 - 2.4e-14 51.9 0.9 3.6e-14 51.4 0.1 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Dynamin_M PF01031.15 EPX75307.1 - 0.059 12.1 0.0 0.08 11.7 0.0 1.1 1 0 0 1 1 1 0 Dynamin central region Sad1_UNC PF07738.8 EPX75308.1 - 0.00078 19.2 0.0 0.0025 17.5 0.0 2.0 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal GATase_2 PF00310.16 EPX75309.1 - 9.2e-27 93.6 0.0 9e-21 73.9 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EPX75309.1 - 1.4e-14 54.1 0.0 3.4e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EPX75309.1 - 8.2e-14 51.4 0.0 1.5e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EPX75309.1 - 2.9e-10 39.9 0.0 5.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EPX75309.1 - 9.7e-06 24.4 0.0 1.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II NTP_transferase PF00483.18 EPX75310.1 - 1.1e-11 44.4 0.0 4.8e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EPX75310.1 - 6e-05 23.1 0.0 8.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EPX75310.1 - 0.00015 21.1 13.0 0.03 13.8 2.3 3.5 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EPX75310.1 - 0.031 13.8 15.8 0.2 11.2 3.1 2.9 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Spt20 PF12090.3 EPX75311.1 - 1.9e-43 147.9 1.0 1.9e-43 147.9 0.7 2.7 3 0 0 3 3 3 2 Spt20 family DUF1746 PF08508.5 EPX75312.1 - 1.8e-28 98.8 6.1 2.4e-28 98.4 4.2 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) HNF-1A_C PF04813.7 EPX75313.1 - 0.067 13.4 0.2 0.094 12.9 0.1 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus ATP_bind_1 PF03029.12 EPX75314.1 - 2.1e-84 282.7 0.0 2.4e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MobB PF03205.9 EPX75314.1 - 0.027 14.1 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EPX75314.1 - 0.12 11.8 0.0 0.26 10.6 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PPV_E1_C PF00519.12 EPX75314.1 - 0.19 10.3 0.6 0.33 9.5 0.1 1.5 2 0 0 2 2 2 0 Papillomavirus helicase FF PF01846.14 EPX75315.1 - 1.4e-47 159.4 10.5 1.9e-12 46.9 0.2 5.8 5 0 0 5 5 5 5 FF domain WW PF00397.21 EPX75315.1 - 4.3e-15 55.2 17.2 4.2e-09 36.0 1.2 3.0 3 0 0 3 3 3 2 WW domain SNF2_N PF00176.18 EPX75316.1 - 1.1e-70 237.7 0.9 2.5e-70 236.6 0.6 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EPX75316.1 - 7e-26 89.6 1.2 1.2e-12 47.2 0.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 EPX75316.1 - 1.4e-25 89.4 2.4 2.1e-25 88.8 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 EPX75316.1 - 3.6e-13 49.1 0.0 2.3e-12 46.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPX75316.1 - 2.5e-07 30.6 0.0 2.8e-06 27.3 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.6 EPX75316.1 - 0.0099 15.6 0.0 0.044 13.5 0.0 2.1 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain DSS1_SEM1 PF05160.8 EPX75317.1 - 1e-20 73.2 14.2 1.1e-20 73.1 9.9 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family DUF4624 PF15417.1 EPX75317.1 - 0.013 15.1 2.5 0.021 14.4 0.6 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4624) YL1 PF05764.8 EPX75317.1 - 0.22 11.1 2.9 0.23 11.0 2.0 1.0 1 0 0 1 1 1 0 YL1 nuclear protein DUF2947 PF11163.3 EPX75317.1 - 0.42 10.1 3.4 0.46 10.0 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) Maf PF02545.9 EPX75318.1 - 5.2e-50 169.2 0.0 6.5e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein RRM_1 PF00076.17 EPX75319.1 - 1.4e-28 98.3 0.4 4.1e-17 61.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPX75319.1 - 4.3e-28 97.0 0.4 2e-15 56.5 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPX75319.1 - 5.2e-10 39.0 0.0 0.00033 20.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tropomodulin PF03250.9 EPX75319.1 - 0.021 14.3 0.2 0.064 12.7 0.2 1.7 1 0 0 1 1 1 0 Tropomodulin Mpv17_PMP22 PF04117.7 EPX75320.1 - 9.7e-24 82.7 1.7 9.7e-24 82.7 1.2 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family XPG_N PF00752.12 EPX75321.1 - 5e-38 129.4 0.0 8.5e-38 128.6 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EPX75321.1 - 5.7e-29 100.0 0.0 1e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EPX75321.1 - 1.3e-06 28.6 0.0 4.3e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold CheD PF03975.8 EPX75321.1 - 0.096 12.4 0.0 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 CheD chemotactic sensory transduction HHH_2 PF12826.2 EPX75321.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Evr1_Alr PF04777.8 EPX75322.1 - 3.6e-28 97.3 3.0 3.6e-28 97.3 2.1 1.8 2 0 0 2 2 2 1 Erv1 / Alr family Glyco_transf_20 PF00982.16 EPX75323.1 - 2.6e-143 477.9 2.0 2.6e-143 477.9 1.4 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EPX75323.1 - 1.8e-67 226.7 0.0 3e-67 225.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EPX75323.1 - 2.3e-07 30.6 0.0 0.0021 17.6 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EPX75323.1 - 0.063 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Vps51 PF08700.6 EPX75324.1 - 3.3e-16 58.8 1.3 4.8e-16 58.3 0.9 1.2 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EPX75324.1 - 0.056 13.3 2.2 0.083 12.8 1.6 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Peptidase_M13_N PF05649.8 EPX75324.1 - 0.064 12.2 0.1 0.074 12.0 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M13 Helicase_C_2 PF13307.1 EPX75325.1 - 9.4e-57 191.6 0.0 3.7e-56 189.6 0.0 2.1 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EPX75325.1 - 9.4e-52 174.9 1.0 9.4e-52 174.9 0.7 1.7 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.10 EPX75325.1 - 0.033 14.0 5.9 0.11 12.3 0.1 3.3 3 2 0 3 3 3 0 Type III restriction enzyme, res subunit Ribosomal_L41 PF05162.8 EPX75326.1 - 1.2e-07 31.3 27.7 1.2e-07 31.2 19.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 SNF2_N PF00176.18 EPX75328.1 - 9.9e-71 237.9 5.2 9.9e-71 237.9 3.6 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 EPX75328.1 - 1.1e-48 164.8 25.1 1.1e-48 164.8 17.4 3.4 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 EPX75328.1 - 6.1e-14 51.6 0.0 1.4e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SET PF00856.23 EPX75329.1 - 1.8e-20 73.8 0.2 1.8e-20 73.8 0.1 3.6 2 2 0 2 2 2 1 SET domain SRI PF08236.6 EPX75329.1 - 1.5e-15 56.8 1.2 1.5e-15 56.8 0.8 2.8 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 EPX75329.1 - 0.0035 16.8 0.1 0.0086 15.5 0.1 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain RNR_inhib PF08591.5 EPX75330.1 - 3.1e-10 40.8 0.1 5.3e-10 40.0 0.0 1.5 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Flu_B_NS1 PF02942.9 EPX75330.1 - 0.025 13.5 0.2 0.035 12.9 0.2 1.3 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) SOR_SNZ PF01680.12 EPX75331.1 - 1.9e-114 380.4 5.0 1.9e-114 380.4 3.5 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 EPX75331.1 - 1.1e-07 31.2 4.2 1.4e-06 27.5 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EPX75331.1 - 0.0003 19.7 0.1 0.21 10.3 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EPX75331.1 - 0.0052 16.0 0.2 0.1 11.8 0.0 2.4 3 0 0 3 3 3 1 Histidine biosynthesis protein NMO PF03060.10 EPX75331.1 - 0.019 14.1 4.9 0.024 13.8 0.1 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase NanE PF04131.9 EPX75331.1 - 0.026 13.4 1.0 0.4 9.6 0.0 2.6 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase MlrC_C PF07171.7 EPX75331.1 - 0.045 13.2 0.3 0.082 12.4 0.2 1.5 1 0 0 1 1 1 0 MlrC C-terminus IGPS PF00218.16 EPX75331.1 - 0.058 12.4 0.0 0.33 9.9 0.0 2.1 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase Methyltransf_26 PF13659.1 EPX75332.1 - 1.2e-11 44.7 0.0 2.3e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPX75332.1 - 9.3e-10 38.1 0.0 1.6e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EPX75332.1 - 2.6e-06 27.7 0.1 1.5e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EPX75332.1 - 3.3e-06 26.6 0.0 4.3e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EPX75332.1 - 5e-05 22.9 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.7 EPX75332.1 - 0.00019 20.6 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_18 PF12847.2 EPX75332.1 - 0.00023 21.7 0.0 0.00042 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EPX75332.1 - 0.0032 16.6 0.0 0.0058 15.7 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.13 EPX75332.1 - 0.0051 16.3 0.0 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 EPX75332.1 - 0.0073 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Halogen_Hydrol PF10112.4 EPX75332.1 - 0.028 13.8 0.1 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TRM PF02005.11 EPX75332.1 - 0.042 12.7 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_12 PF08242.7 EPX75332.1 - 0.052 14.0 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Rcd1 PF04078.8 EPX75333.1 - 1.6e-130 433.6 1.5 1.8e-130 433.4 1.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Sec16_C PF12931.2 EPX75335.1 - 1.5e-63 215.1 0.4 2.8e-63 214.3 0.3 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EPX75335.1 - 1.2e-17 63.9 0.4 1.3e-16 60.6 0.0 2.8 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Clr5 PF14420.1 EPX75336.1 - 4.8e-08 32.7 0.9 1.1e-07 31.5 0.6 1.7 1 0 0 1 1 1 1 Clr5 domain STT3 PF02516.9 EPX75337.1 - 2.1e-147 492.0 40.6 3.6e-141 471.4 25.8 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit NIF PF03031.13 EPX75338.1 - 3.1e-25 88.7 1.2 4.1e-25 88.3 0.3 1.5 1 1 1 2 2 2 1 NLI interacting factor-like phosphatase Trp_repressor PF01371.14 EPX75338.1 - 0.084 12.8 0.0 0.64 9.9 0.0 2.4 2 1 0 2 2 2 0 Trp repressor protein DS PF01916.12 EPX75339.1 - 8.9e-143 474.8 0.0 1e-142 474.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase PPR_2 PF13041.1 EPX75339.1 - 0.14 12.1 0.0 0.49 10.4 0.0 1.9 1 0 0 1 1 1 0 PPR repeat family zf-AN1 PF01428.11 EPX75340.1 - 4.6e-09 35.9 10.5 4.6e-09 35.9 7.2 1.6 2 0 0 2 2 2 1 AN1-like Zinc finger ubiquitin PF00240.18 EPX75340.1 - 0.093 12.1 0.0 0.32 10.4 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin family Rad60-SLD PF11976.3 EPX75340.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Sugar_tr PF00083.19 EPX75341.1 - 2.2e-23 82.5 41.0 3.2e-19 68.8 7.0 2.7 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EPX75341.1 - 1.6e-14 53.3 47.7 4.7e-12 45.2 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3671 PF12420.3 EPX75341.1 - 5.6 7.0 6.7 2 8.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function MFS_1 PF07690.11 EPX75342.1 - 1.6e-38 132.3 5.5 1.6e-38 132.3 3.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.22 EPX75343.1 - 3.3e-36 122.8 8.1 8e-15 54.3 0.0 4.4 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3437 PF11919.3 EPX75343.1 - 0.014 15.0 0.1 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Oxysterol_BP PF01237.13 EPX75344.1 - 2.1e-81 273.1 0.2 2.7e-81 272.7 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Ribosomal_L17 PF01196.14 EPX75345.1 - 1.3e-30 105.8 0.1 6.1e-30 103.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L17 ATP-synt_E PF05680.7 EPX75345.1 - 1.4 8.9 8.6 1.3 9.0 0.6 2.3 2 0 0 2 2 2 0 ATP synthase E chain N6_N4_Mtase PF01555.13 EPX75345.1 - 2.8 7.3 5.3 15 5.0 3.7 1.9 1 1 0 1 1 1 0 DNA methylase ArgJ PF01960.13 EPX75346.1 - 9.8e-148 491.6 4.5 1.1e-147 491.5 3.1 1.0 1 0 0 1 1 1 1 ArgJ family GTP_EFTU PF00009.22 EPX75347.1 - 3e-37 127.8 2.4 8.3e-37 126.4 0.5 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EPX75347.1 - 1.2e-25 89.5 0.0 2.7e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EPX75347.1 - 2e-10 40.6 1.1 0.00026 21.0 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPX75347.1 - 9e-09 35.3 0.0 2.2e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.10 EPX75347.1 - 4.5e-07 29.4 0.0 5.1e-05 22.8 0.0 2.7 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 EPX75347.1 - 1.3e-06 28.8 0.0 3.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EPX75347.1 - 0.00011 21.7 0.1 0.00034 20.1 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EPX75347.1 - 0.0017 17.6 0.0 0.009 15.3 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EPX75347.1 - 0.004 15.9 0.5 0.022 13.5 0.2 2.1 1 1 1 2 2 2 1 ArgK protein SRPRB PF09439.5 EPX75347.1 - 0.0085 15.3 0.0 0.021 14.0 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EPX75347.1 - 0.018 14.4 0.3 0.037 13.4 0.0 1.7 2 0 0 2 2 2 0 Ras family GTP_EFTU_D4 PF14578.1 EPX75347.1 - 0.022 14.3 5.6 0.038 13.6 0.5 2.6 3 0 0 3 3 3 0 Elongation factor Tu domain 4 AAA_29 PF13555.1 EPX75347.1 - 0.023 14.2 0.2 0.41 10.2 0.0 2.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain FANCI_S1-cap PF14674.1 EPX75347.1 - 0.026 14.5 0.1 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 FANCI solenoid 1 cap Dynamin_N PF00350.18 EPX75347.1 - 0.03 14.1 2.2 0.28 10.9 0.0 2.7 2 1 1 3 3 3 0 Dynamin family Iron_permease PF04120.7 EPX75348.1 - 1.1e-40 138.2 14.7 3.6e-13 49.2 0.2 4.2 4 0 0 4 4 4 4 Low affinity iron permease NfeD PF01957.13 EPX75348.1 - 6 7.0 11.2 18 5.4 0.1 3.9 4 0 0 4 4 4 0 NfeD-like C-terminal, partner-binding Aminotran_3 PF00202.16 EPX75349.1 - 3.8e-86 289.0 0.0 4.5e-86 288.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Epimerase PF01370.16 EPX75350.1 - 9.6e-24 84.1 0.1 1.8e-23 83.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPX75350.1 - 4.2e-16 58.4 0.0 7.5e-16 57.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPX75350.1 - 4.4e-13 48.7 0.0 1.5e-09 37.1 0.0 2.5 2 1 0 3 3 3 2 Male sterility protein Polysacc_synt_2 PF02719.10 EPX75350.1 - 4.6e-08 32.3 0.0 6.7e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EPX75350.1 - 4e-06 26.9 0.1 1.3e-05 25.3 0.0 1.9 2 1 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EPX75350.1 - 0.00049 20.0 0.1 0.002 18.0 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EPX75350.1 - 0.0069 15.6 0.1 0.054 12.7 0.0 2.3 2 1 0 2 2 2 1 NmrA-like family KR PF08659.5 EPX75350.1 - 0.038 13.6 0.4 0.31 10.6 0.1 2.2 2 1 0 2 2 2 0 KR domain RmlD_sub_bind PF04321.12 EPX75350.1 - 0.068 12.0 0.0 0.16 10.8 0.0 1.7 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_N PF08240.7 EPX75351.1 - 8.8e-33 112.3 0.2 1.9e-32 111.2 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPX75351.1 - 3.3e-17 62.2 0.0 6.4e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EPX75351.1 - 3e-06 27.7 0.0 5.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EPX75351.1 - 0.00031 21.6 0.0 0.00081 20.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EPX75351.1 - 0.0027 17.3 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EPX75351.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTS PF05175.9 EPX75351.1 - 0.024 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.15 EPX75351.1 - 0.03 13.3 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TrkA_N PF02254.13 EPX75351.1 - 0.056 13.4 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_11 PF08241.7 EPX75351.1 - 0.093 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EPX75351.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_23 PF13489.1 EPX75351.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 EPX75351.1 - 0.12 11.9 0.3 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PrmA PF06325.8 EPX75351.1 - 0.12 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EPX75351.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EPX75351.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain YdfZ PF14001.1 EPX75351.1 - 0.96 9.7 3.1 0.99 9.7 0.0 2.6 3 0 0 3 3 2 0 YdfZ protein ADH_zinc_N PF00107.21 EPX75352.1 - 2.8e-27 94.8 0.2 4.2e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPX75352.1 - 3.6e-17 63.4 0.0 1.1e-16 61.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPX75352.1 - 2.3e-14 53.0 0.0 1.1e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EPX75352.1 - 0.012 15.2 0.1 0.03 13.8 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 EPX75352.1 - 0.066 12.7 0.2 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ran_BP1 PF00638.13 EPX75353.1 - 5.9e-49 165.1 0.6 9.8e-49 164.4 0.4 1.3 1 0 0 1 1 1 1 RanBP1 domain Glyco_transf_15 PF01793.11 EPX75354.1 - 2.8e-125 417.6 11.0 3.6e-125 417.3 7.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Dna2 PF08696.6 EPX75354.1 - 0.14 11.4 0.0 0.72 9.1 0.0 1.9 2 0 0 2 2 2 0 DNA replication factor Dna2 DnaJ PF00226.26 EPX75355.1 - 8.9e-21 73.4 0.3 8.9e-21 73.4 0.2 2.3 2 0 0 2 2 2 1 DnaJ domain DUF4624 PF15417.1 EPX75355.1 - 0.023 14.3 0.1 0.051 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4624) tRNA-synt_2 PF00152.15 EPX75356.1 - 3.5e-75 252.8 0.3 4.7e-75 252.4 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPX75356.1 - 1.2e-11 44.2 0.0 2.2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CDC50 PF03381.10 EPX75357.1 - 1.2e-102 342.8 0.1 1.6e-102 342.4 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family AhpC-TSA PF00578.16 EPX75358.1 - 5.2e-26 90.7 0.0 7e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPX75358.1 - 5.4e-16 58.4 0.0 6.6e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EPX75358.1 - 0.00022 21.1 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Striatin PF08232.7 EPX75359.1 - 8.2e-25 87.6 6.1 4.8e-24 85.1 4.2 2.1 1 1 0 1 1 1 1 Striatin family WD40 PF00400.27 EPX75359.1 - 2.2e-16 59.0 0.9 4.8e-08 32.5 0.4 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-C4H2 PF10146.4 EPX75359.1 - 0.012 15.6 3.9 0.019 15.0 2.7 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein HlyD PF00529.15 EPX75359.1 - 0.048 12.9 0.6 0.067 12.4 0.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein CENP-T PF15511.1 EPX75360.1 - 1.2e-24 87.3 29.5 2.1e-24 86.5 20.5 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EPX75360.1 - 4.2e-09 36.4 0.1 8.4e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EPX75360.1 - 1.5e-08 34.6 0.1 3.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EPX75360.1 - 8.3e-05 22.2 0.0 0.00021 20.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated UDPG_MGDP_dh_N PF03721.9 EPX75360.1 - 0.0087 15.4 0.0 2.6 7.3 0.0 2.4 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CBFD_NFYB_HMF PF00808.18 EPX75360.1 - 0.0088 16.0 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EPX75360.1 - 0.024 14.9 0.1 0.069 13.4 0.1 1.8 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A LAGLIDADG_WhiA PF14527.1 EPX75360.1 - 0.094 12.5 0.1 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain ubiquitin PF00240.18 EPX75361.1 - 5.6e-09 35.2 0.0 9.5e-09 34.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPX75361.1 - 0.017 14.8 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like EF-hand_4 PF12763.2 EPX75362.1 - 2.3e-37 126.8 0.0 6.4e-13 48.3 0.0 3.7 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EPX75362.1 - 7.7e-13 48.3 0.0 0.00022 21.3 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EPX75362.1 - 7.3e-10 37.4 0.1 0.075 12.3 0.0 5.3 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EPX75362.1 - 5e-06 25.9 0.6 8.7 6.5 0.0 5.3 4 1 1 5 5 5 0 EF-hand domain AAA_13 PF13166.1 EPX75362.1 - 0.0016 17.0 22.1 0.0029 16.1 15.3 1.5 1 0 0 1 1 1 1 AAA domain DUF960 PF06124.6 EPX75362.1 - 0.0028 17.8 0.3 6.1 7.1 0.0 3.7 4 0 0 4 4 3 1 Staphylococcal protein of unknown function (DUF960) EF-hand_8 PF13833.1 EPX75362.1 - 0.0097 15.5 0.2 1.2 8.7 0.0 4.0 4 1 1 5 5 5 1 EF-hand domain pair Reo_sigmaC PF04582.7 EPX75362.1 - 0.0099 15.0 21.3 0.011 14.8 8.8 2.4 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Laminin_I PF06008.9 EPX75362.1 - 0.037 13.3 30.7 0.063 12.5 21.3 1.2 1 0 0 1 1 1 0 Laminin Domain I AAA_27 PF13514.1 EPX75362.1 - 0.083 10.5 24.2 0.12 10.0 16.7 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EPX75362.1 - 0.12 11.4 32.6 1.8 7.5 9.1 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3584 PF12128.3 EPX75362.1 - 0.16 9.2 29.4 0.24 8.7 20.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 EPX75362.1 - 0.17 9.5 33.5 0.43 8.2 3.8 2.1 1 1 1 2 2 2 0 Myosin tail DUF812 PF05667.6 EPX75362.1 - 0.2 10.1 31.8 0.9 7.9 10.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) GAS PF13851.1 EPX75362.1 - 0.32 10.1 33.2 0.7 9.0 13.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EPX75362.1 - 0.57 9.9 15.6 1.9 8.2 1.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMCO5 PF14992.1 EPX75362.1 - 0.8 8.7 29.7 3.1 6.8 20.4 2.1 1 1 0 1 1 1 0 TMCO5 family TPR_MLP1_2 PF07926.7 EPX75362.1 - 1.2 8.8 37.6 0.69 9.6 15.1 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Rab5-bind PF09311.6 EPX75362.1 - 3.8 7.3 32.9 0.52 10.1 7.1 2.8 1 1 1 2 2 2 0 Rabaptin-like protein NPV_P10 PF05531.7 EPX75362.1 - 4.3 7.6 12.4 12 6.2 3.6 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.8 EPX75362.1 - 7.3 7.3 16.6 0.26 12.0 0.8 3.1 3 0 0 3 3 2 0 Occludin homology domain Zn_clus PF00172.13 EPX75363.1 - 4.4e-06 26.5 17.4 1.1e-05 25.1 12.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 EPX75364.1 - 1e-49 169.0 9.0 1e-49 169.0 6.2 1.9 1 1 1 2 2 2 1 RTA1 like protein 7TM_GPCR_Srw PF10324.4 EPX75364.1 - 0.034 13.2 1.6 0.063 12.3 1.1 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw TM_helix PF05552.7 EPX75364.1 - 1.3 8.7 9.4 0.43 10.2 0.7 3.5 3 1 0 3 3 3 0 Conserved TM helix Ribosomal_L4 PF00573.17 EPX75366.1 - 8.4e-45 152.5 1.4 1.1e-44 152.0 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EPX75366.1 - 2.5e-27 94.5 3.4 2.5e-27 94.5 2.4 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PIF1 PF05970.9 EPX75366.1 - 0.045 12.6 0.1 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase SRP40_C PF05022.7 EPX75367.1 - 4.9e-27 94.2 2.8 1.3e-26 92.8 1.9 1.8 1 0 0 1 1 1 1 SRP40, C-terminal domain LisH PF08513.6 EPX75367.1 - 2.8e-05 23.7 0.0 5.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 LisH THF_DHG_CYH PF00763.18 EPX75368.1 - 9.5e-20 70.7 0.0 2.6e-19 69.3 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EPX75368.1 - 3.8e-15 55.3 0.0 3.2e-12 45.8 0.0 3.5 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TAFH PF07531.9 EPX75368.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 NHR1 homology to TAF SBP_bac_5 PF00496.17 EPX75368.1 - 0.055 12.2 0.0 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle DUF106 PF01956.11 EPX75369.1 - 6.7e-52 175.4 2.3 8.7e-52 175.0 1.6 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 RTA1 PF04479.8 EPX75370.1 - 1.4e-62 211.1 2.9 1.4e-62 211.1 2.0 1.3 2 0 0 2 2 2 1 RTA1 like protein DUF202 PF02656.10 EPX75370.1 - 1.1 9.4 4.5 5 7.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF1218 PF06749.7 EPX75370.1 - 3.5 8.1 7.6 7.8 7.0 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) CN_hydrolase PF00795.17 EPX75371.1 - 5.1e-35 120.5 0.0 6.4e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase dCMP_cyt_deam_1 PF00383.17 EPX75372.1 - 3.6e-22 77.9 0.1 4.6e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EPX75372.1 - 5.5e-06 26.1 0.6 1.2e-05 25.0 0.4 1.5 1 1 0 1 1 1 1 APOBEC-like N-terminal domain LON PF02190.11 EPX75372.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain MFS_1 PF07690.11 EPX75373.1 - 1.5e-34 119.2 30.9 1.5e-34 119.2 21.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX75373.1 - 5.2e-07 28.5 36.5 4.1e-06 25.6 25.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Fun_ATP-synt_8 PF05933.8 EPX75373.1 - 3.2 7.8 15.9 0.2 11.6 1.3 3.7 3 0 0 3 3 3 0 Fungal ATP synthase protein 8 (A6L) Hexapep_2 PF14602.1 EPX75374.1 - 2.1e-14 52.7 10.6 3.1e-12 45.8 3.5 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EPX75374.1 - 1.3e-13 49.7 8.4 4e-11 41.8 3.4 2.7 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EPX75374.1 - 7.1e-10 38.7 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase DIOX_N PF14226.1 EPX75375.1 - 6.9e-26 91.0 0.0 1.2e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPX75375.1 - 4.1e-20 71.9 0.0 6.1e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PCMT PF01135.14 EPX75376.1 - 1.8e-65 220.3 0.0 2.2e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EPX75376.1 - 6.2e-09 36.4 0.0 1e-08 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPX75376.1 - 1.6e-07 30.9 0.1 3.9e-07 29.7 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPX75376.1 - 6.6e-06 25.4 0.0 9.1e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EPX75376.1 - 3.1e-05 23.9 0.0 5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPX75376.1 - 3.2e-05 24.3 0.0 6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPX75376.1 - 7.8e-05 22.1 0.1 0.00013 21.4 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EPX75376.1 - 0.0001 22.1 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPX75376.1 - 0.00011 21.4 0.0 0.00015 21.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EPX75376.1 - 0.00037 19.5 0.0 0.00054 19.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GCD14 PF08704.5 EPX75376.1 - 0.0004 19.9 0.0 0.00054 19.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_32 PF13679.1 EPX75376.1 - 0.00068 19.3 0.1 0.0014 18.2 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPX75376.1 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EPX75376.1 - 0.004 16.2 0.0 0.0063 15.5 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Fibrillarin PF01269.12 EPX75376.1 - 0.0096 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin DOT1 PF08123.8 EPX75376.1 - 0.035 13.4 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 CMAS PF02353.15 EPX75376.1 - 0.042 12.9 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EPX75376.1 - 0.052 13.5 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 EPX75376.1 - 0.072 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EPX75376.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 EPX75376.1 - 0.13 13.1 0.0 0.22 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EPX75376.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MetW PF07021.7 EPX75376.1 - 0.16 11.3 0.1 0.52 9.6 0.1 1.7 1 1 0 2 2 2 0 Methionine biosynthesis protein MetW DJ-1_PfpI PF01965.19 EPX75377.1 - 3.2e-29 101.3 0.1 4.7e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EPX75377.1 - 0.0025 17.2 0.0 0.0051 16.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF587 PF04532.7 EPX75377.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF587) DUF2424 PF10340.4 EPX75378.1 - 5.8e-58 196.3 0.8 6.6e-58 196.1 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EPX75378.1 - 7e-19 68.2 0.0 9.3e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPX75378.1 - 0.0018 18.0 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family M-factor PF03855.8 EPX75379.1 - 4.3e-05 23.4 5.8 6.2e-05 22.9 4.0 1.3 1 0 0 1 1 1 1 M-factor Hemerythrin PF01814.18 EPX75380.1 - 7.8e-14 51.9 0.1 1.2e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Spt20 PF12090.3 EPX75380.1 - 0.063 12.6 0.5 0.087 12.1 0.4 1.2 1 0 0 1 1 1 0 Spt20 family Sugar_tr PF00083.19 EPX75381.1 - 2.1e-111 372.6 22.9 2.9e-111 372.2 15.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPX75381.1 - 9.9e-23 80.4 26.3 7.5e-18 64.3 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EPX75381.1 - 0.3 9.1 3.2 0.44 8.6 2.2 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector MFS_1 PF07690.11 EPX75382.1 - 1.7e-17 63.1 18.9 2.4e-17 62.7 13.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CagY_M PF07337.6 EPX75382.1 - 0.1 12.0 0.5 0.23 10.9 0.3 1.6 1 0 0 1 1 1 0 DC-EC Repeat FAD_binding_8 PF08022.7 EPX75383.1 - 2.4e-28 98.0 0.0 9.7e-28 96.1 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EPX75383.1 - 1.7e-16 60.5 0.4 2.1e-15 56.9 0.0 2.6 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPX75383.1 - 1.9e-10 40.8 6.2 1.9e-10 40.8 4.3 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EPX75383.1 - 0.016 15.7 0.0 0.12 12.9 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain 7TMR-DISM_7TM PF07695.6 EPX75383.1 - 0.3 10.7 18.0 0.36 10.4 6.7 2.4 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF4131 PF13567.1 EPX75383.1 - 0.52 9.6 7.1 6.9 6.0 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TSP9 PF11493.3 EPX75384.1 - 0.0075 16.7 0.4 5.8 7.5 0.0 3.0 1 1 1 3 3 3 1 Thylakoid soluble phosphoprotein TSP9 Hce2 PF14856.1 EPX75384.1 - 0.044 13.6 1.7 9.5 6.2 0.1 3.1 1 1 3 4 4 4 0 Pathogen effector; putative necrosis-inducing factor DUF1658 PF07871.6 EPX75384.1 - 0.066 12.8 14.0 55 3.5 0.0 6.6 9 0 0 9 9 9 0 Protein of unknown function (DUF1658) CoatB PF10389.4 EPX75384.1 - 9.2 6.2 11.0 86 3.1 0.1 4.8 1 1 4 5 5 5 0 Bacteriophage coat protein B MFS_1 PF07690.11 EPX75385.1 - 2e-34 118.8 26.0 2.7e-34 118.4 18.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EPX75385.1 - 0.19 12.1 4.3 3.3 8.1 0.2 3.0 2 1 1 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Amidohydro_1 PF01979.15 EPX75386.1 - 1.2e-39 136.8 0.0 1.5e-39 136.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EPX75386.1 - 6.1e-15 55.9 0.1 3e-07 30.7 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EPX75386.1 - 3.4e-11 42.7 0.1 1.2e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EPX75386.1 - 2.7e-10 40.0 0.0 6.5e-07 28.9 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family His_Phos_1 PF00300.17 EPX75387.1 - 6.8e-26 91.2 0.0 8.7e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Enolase_C PF00113.17 EPX75388.1 - 1.7e-133 444.2 0.1 2.1e-133 443.8 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EPX75388.1 - 6.5e-54 181.4 0.1 1.4e-53 180.2 0.0 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MAAL_C PF07476.6 EPX75388.1 - 0.00019 20.4 0.0 0.00031 19.7 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 EPX75388.1 - 0.00044 20.1 0.0 0.00094 19.1 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EPX75388.1 - 0.0063 17.0 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF823 PF05689.6 EPX75388.1 - 0.051 12.9 0.0 0.11 11.7 0.0 1.5 1 1 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) DUF3885 PF13021.1 EPX75388.1 - 1.5 8.6 4.4 3.6 7.3 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) CsbD PF05532.7 EPX75389.1 - 0.0078 15.8 1.9 0.014 15.0 1.3 1.4 1 0 0 1 1 1 1 CsbD-like DIOX_N PF14226.1 EPX75390.1 - 3.9e-24 85.4 0.0 7.5e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPX75390.1 - 1.4e-14 54.1 0.1 3.2e-14 53.0 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily HTH_39 PF14090.1 EPX75390.1 - 0.16 11.4 0.0 0.51 9.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain MFS_1 PF07690.11 EPX75393.1 - 5.4e-38 130.6 34.6 5.4e-38 130.6 24.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPX75393.1 - 1.4e-12 46.9 11.4 1.4e-12 46.9 7.9 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter RseC_MucC PF04246.7 EPX75393.1 - 3.2 7.3 7.9 0.29 10.7 0.1 3.0 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Trehalose_recp PF06151.8 EPX75394.1 - 0.097 11.0 2.0 0.13 10.5 1.4 1.1 1 0 0 1 1 1 0 Trehalose receptor Lactamase_B_2 PF12706.2 EPX75395.1 - 1.8e-22 79.8 0.0 2.3e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPX75395.1 - 1.9e-07 30.9 0.0 2.5e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPX75395.1 - 0.012 15.2 0.2 0.018 14.6 0.1 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF1772 PF08592.6 EPX75396.1 - 9.9 5.8 9.0 12 5.6 0.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) SnoaL_4 PF13577.1 EPX75397.1 - 9.7e-14 51.3 2.0 2.2e-08 34.0 0.0 2.0 1 1 1 2 2 2 2 SnoaL-like domain DUF3505 PF12013.3 EPX75398.1 - 0.00018 21.7 0.2 0.0011 19.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) DEAD PF00270.24 EPX75399.1 - 1.1e-11 44.4 0.0 6.9e-11 41.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase