# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Minor_capsid_2 PF11114.8 KLO03703.1 - 0.025 14.6 0.1 0.047 13.7 0.1 1.5 1 0 0 1 1 1 0 Minor capsid protein F-box PF00646.33 KLO03704.1 - 0.00011 21.9 0.1 0.00018 21.3 0.1 1.3 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KLO03704.1 - 0.0051 16.7 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KLO03704.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 F-box-like zf-CCHC PF00098.23 KLO03705.1 - 0.0024 17.9 3.3 0.0043 17.1 3.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Adaptin_binding PF10199.9 KLO03705.1 - 0.053 14.1 3.1 0.086 13.5 3.1 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 GAGA_bind PF06217.12 KLO03705.1 - 0.077 13.3 1.6 0.12 12.6 1.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family T6SS_VasJ PF16989.5 KLO03705.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ NAM-associated PF14303.6 KLO03705.1 - 0.21 12.3 8.1 0.33 11.7 8.1 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain AF-4 PF05110.13 KLO03705.1 - 0.24 9.5 8.8 0.33 9.0 8.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDC45 PF02724.14 KLO03705.1 - 0.53 8.5 9.0 0.69 8.1 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CCDC106 PF15794.5 KLO03705.1 - 0.91 9.2 5.8 1.3 8.6 5.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Presenilin PF01080.17 KLO03705.1 - 1.6 7.5 2.3 2 7.1 2.3 1.1 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 KLO03705.1 - 7.3 4.6 9.1 9 4.3 9.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 KLO03707.1 - 2.6e-25 88.2 9.9 4.7e-08 33.6 0.9 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO03707.1 - 1.1e-11 44.9 0.1 0.0019 18.5 0.0 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KLO03707.1 - 0.00017 21.4 0.2 0.98 9.4 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KLO03707.1 - 0.00082 18.4 0.1 5.8 5.8 0.0 3.1 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KLO03707.1 - 0.0077 14.9 0.4 0.5 8.9 0.1 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KLO03707.1 - 0.0086 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KLO03707.1 - 0.025 13.9 0.6 0.28 10.5 0.1 2.4 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Paramyxo_PNT PF14320.6 KLO03707.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoprotein P region PNT disordered Ret2_MD PF18528.1 KLO03707.1 - 0.16 12.4 0.0 8.2 6.9 0.0 3.0 2 1 1 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Zn_clus PF00172.18 KLO03709.1 - 2.8e-09 37.0 22.8 9.8e-05 22.4 7.3 2.1 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_tube PF04985.14 KLO03712.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Phage tail tube protein FII FSH1 PF03959.13 KLO03713.1 - 0.033 13.9 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAG6 PF12057.8 KLO03713.1 - 0.079 12.6 0.2 2.7 7.7 0.0 2.2 1 1 1 2 2 2 0 BCL2-associated athanogene 6 YL1 PF05764.13 KLO03716.1 - 8e-06 26.1 11.8 9.1e-06 26.0 11.8 1.1 1 0 0 1 1 1 1 YL1 nuclear protein zf-CCHC PF00098.23 KLO03716.1 - 0.0025 17.8 1.8 0.0043 17.1 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle Utp14 PF04615.13 KLO03716.1 - 0.012 14.2 13.3 0.015 14.0 13.3 1.0 1 0 0 1 1 1 0 Utp14 protein MFMR_assoc PF16596.5 KLO03716.1 - 0.058 13.9 6.3 0.081 13.4 6.3 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR T6SS_VasJ PF16989.5 KLO03716.1 - 0.068 12.6 0.1 0.097 12.1 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ CDC45 PF02724.14 KLO03716.1 - 0.073 11.4 14.2 0.081 11.2 14.2 1.0 1 0 0 1 1 1 0 CDC45-like protein NAM-associated PF14303.6 KLO03716.1 - 0.34 11.6 13.0 0.43 11.3 13.0 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Secretin_N_2 PF07655.13 KLO03716.1 - 0.64 10.6 4.5 0.91 10.1 4.5 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Adaptin_binding PF10199.9 KLO03716.1 - 0.7 10.5 12.1 1.7 9.2 12.1 1.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 SR-25 PF10500.9 KLO03716.1 - 0.93 9.1 12.8 1.3 8.6 12.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 KLO03716.1 - 3.1 7.0 25.0 0.061 12.7 18.6 1.3 2 0 0 2 2 2 0 BUD22 CCDC106 PF15794.5 KLO03716.1 - 3.7 7.2 9.6 4.5 6.9 9.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DNA_pol_phi PF04931.13 KLO03716.1 - 4.1 5.4 17.4 5 5.1 17.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 KLO03716.1 - 5.3 6.9 14.4 8.3 6.2 14.4 1.3 1 1 0 1 1 1 0 Sigma-70, non-essential region GET2 PF08690.10 KLO03716.1 - 5.8 6.5 9.8 7.2 6.2 9.8 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Zip PF02535.22 KLO03716.1 - 7.5 5.7 5.1 9.1 5.4 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter YL1 PF05764.13 KLO03717.1 - 7.5e-06 26.2 12.7 7.5e-06 26.2 12.7 1.6 2 0 0 2 2 2 1 YL1 nuclear protein AF-4 PF05110.13 KLO03717.1 - 0.00047 18.4 9.1 0.0008 17.6 9.1 1.3 1 0 0 1 1 1 1 AF-4 proto-oncoprotein zf-CCHC PF00098.23 KLO03717.1 - 0.005 16.9 1.8 0.0081 16.2 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle T6SS_VasJ PF16989.5 KLO03717.1 - 0.021 14.3 0.1 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ BUD22 PF09073.10 KLO03717.1 - 0.029 13.7 21.7 0.026 13.9 18.2 2.1 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.14 KLO03717.1 - 0.045 12.0 14.9 0.063 11.6 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.13 KLO03717.1 - 0.063 11.8 14.6 0.093 11.3 14.6 1.1 1 0 0 1 1 1 0 Utp14 protein Sigma70_ner PF04546.13 KLO03717.1 - 0.071 13.0 9.0 0.12 12.2 9.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Secretin_N_2 PF07655.13 KLO03717.1 - 0.11 13.0 1.2 0.21 12.1 1.2 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain CENP-B_dimeris PF09026.10 KLO03717.1 - 0.35 11.3 10.6 0.84 10.1 10.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4614 PF15391.6 KLO03717.1 - 0.39 10.7 6.4 0.71 9.8 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Cwf_Cwc_15 PF04889.12 KLO03717.1 - 0.44 10.2 17.8 0.79 9.4 17.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CCDC106 PF15794.5 KLO03717.1 - 1.4 8.6 8.6 2.6 7.7 8.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Zip PF02535.22 KLO03717.1 - 2.9 7.0 4.3 3.5 6.8 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SDA1 PF05285.12 KLO03717.1 - 3.3 7.0 20.8 4.6 6.6 20.8 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KLO03717.1 - 3.9 5.5 19.7 4.9 5.1 19.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Apt1 PF10351.9 KLO03717.1 - 4 6.2 8.6 5.5 5.7 8.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SURF2 PF05477.11 KLO03717.1 - 7.3 6.2 14.2 14 5.3 14.2 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Adaptin_binding PF10199.9 KLO03717.1 - 7.6 7.2 13.9 31 5.2 13.9 1.9 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF3684 PF12449.8 KLO03718.1 - 0.043 11.6 0.0 0.047 11.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) KOW PF00467.29 KLO03719.1 - 1.2e-10 41.0 12.9 0.012 15.6 0.0 4.3 4 0 0 4 4 4 3 KOW motif DUF4438 PF14505.6 KLO03719.1 - 0.11 11.5 3.4 8.3 5.3 0.0 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4438) RNase_H PF00075.24 KLO03721.1 - 0.0042 17.3 0.0 0.0042 17.3 0.0 1.1 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 KLO03722.1 - 0.00052 20.7 0.3 0.0007 20.3 0.3 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase TetR_C_29 PF17938.1 KLO03722.1 - 0.066 13.3 0.0 0.098 12.8 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-C2H2_4 PF13894.6 KLO03724.1 - 0.12 13.3 0.8 0.99 10.4 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KLO03724.1 - 0.13 12.6 0.2 1.8 9.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KLO03724.1 - 0.52 10.4 4.4 0.3 11.1 0.5 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger DUF5334 PF17268.2 KLO03725.1 - 0.0087 16.4 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5334) YafQ_toxin PF15738.5 KLO03725.1 - 0.17 12.3 0.2 0.26 11.6 0.2 1.3 1 0 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ DUF5334 PF17268.2 KLO03729.1 - 0.02 15.2 0.1 0.042 14.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5334) SNF2_N PF00176.23 KLO03731.1 - 0.041 12.6 0.0 0.072 11.8 0.0 1.3 1 1 0 1 1 1 0 SNF2 family N-terminal domain KDZ PF18758.1 KLO03733.1 - 3.3e-31 108.6 1.5 3.6e-31 108.5 1.5 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Aldo_ket_red PF00248.21 KLO03737.1 - 1.8e-09 37.3 0.0 2.1e-09 37.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-Di19 PF05605.12 KLO03740.1 - 0.0051 17.1 0.5 0.0051 17.1 0.5 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Med27 PF11571.8 KLO03740.1 - 0.26 11.7 8.3 0.043 14.2 2.9 2.3 2 1 1 3 3 3 0 Mediator complex subunit 27 Phage_integrase PF00589.22 KLO03742.1 - 4.3e-05 23.4 0.0 7.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Spt5-NGN PF03439.13 KLO03743.1 - 1.9e-09 37.3 0.0 3.4e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DNA_pol_phi PF04931.13 KLO03743.1 - 2.3 6.2 4.9 3.1 5.8 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4816 PF16086.5 KLO03745.1 - 0.54 10.2 0.0 0.54 10.2 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4816) Aldose_epim PF01263.20 KLO03746.1 - 5.7e-43 147.3 0.0 6.7e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase GTF2I PF02946.14 KLO03749.1 - 0.093 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 GTF2I-like repeat Gemini_mov PF01708.16 KLO03752.1 - 0.089 12.6 0.6 0.094 12.5 0.6 1.1 1 0 0 1 1 1 0 Geminivirus putative movement protein HIN PF02760.15 KLO03753.1 - 0.072 12.8 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 HIN-200/IF120x domain Patatin PF01734.22 KLO03755.1 - 6.2e-05 23.3 0.0 7.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Cwf_Cwc_15 PF04889.12 KLO03756.1 - 0.062 13.0 4.5 0.077 12.7 4.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 KLO03756.1 - 0.32 11.0 5.5 0.33 10.9 5.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 KLO03756.1 - 0.92 8.8 7.1 1.1 8.6 7.1 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KLO03756.1 - 1.1 7.4 6.7 1.1 7.3 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 KLO03756.1 - 1.4 8.0 4.1 1.6 7.9 4.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ssu72 PF04722.13 KLO03759.1 - 7.9e-05 22.3 0.1 0.00012 21.7 0.1 1.3 1 1 0 1 1 1 1 Ssu72-like protein F-box-like PF12937.7 KLO03761.1 - 0.00071 19.4 0.0 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 F-box-like DUF3605 PF12239.8 KLO03761.1 - 0.045 14.1 0.1 0.06 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) THDPS_M PF14789.6 KLO03762.1 - 0.029 14.5 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase middle AAA PF00004.29 KLO03765.1 - 1.7e-44 151.4 0.1 2.5e-44 150.9 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 KLO03765.1 - 1.8e-08 34.1 0.0 3.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.14 KLO03765.1 - 2.6e-08 34.2 0.0 4.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KLO03765.1 - 3e-07 30.5 0.2 1.2e-06 28.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KLO03765.1 - 6.1e-07 29.3 0.0 2.7e-06 27.2 0.0 2.1 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain CDC48_N PF02359.18 KLO03765.1 - 9.4e-07 28.9 0.1 3.8e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_33 PF13671.6 KLO03765.1 - 1.7e-06 28.2 0.0 3.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KLO03765.1 - 0.00013 22.2 0.1 0.016 15.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KLO03765.1 - 0.0003 20.1 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain ATPase PF06745.13 KLO03765.1 - 0.00033 20.1 0.2 0.37 10.1 0.0 2.2 2 0 0 2 2 2 2 KaiC AAA_16 PF13191.6 KLO03765.1 - 0.00083 19.8 0.0 0.025 15.0 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KLO03765.1 - 0.0024 17.5 0.3 0.79 9.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KLO03765.1 - 0.003 17.6 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KLO03765.1 - 0.0094 15.4 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI UFD1 PF03152.14 KLO03765.1 - 0.014 14.9 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 IstB_IS21 PF01695.17 KLO03765.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.15 KLO03765.1 - 0.016 15.2 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 KLO03765.1 - 0.024 14.4 0.0 0.18 11.5 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 KLO03765.1 - 0.031 14.8 0.0 0.062 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KLO03765.1 - 0.042 13.6 0.0 0.11 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KLO03765.1 - 0.099 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KLO03765.1 - 0.1 12.1 0.0 0.31 10.5 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KLO03765.1 - 0.12 11.8 0.1 0.26 10.7 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 KLO03765.1 - 0.12 12.7 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KLO03765.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KLO03766.1 - 1.4e-06 27.7 0.0 2e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KLO03766.1 - 6.8e-05 23.3 0.0 7e-05 23.3 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO03766.1 - 0.00042 20.6 0.0 0.00051 20.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KLO03766.1 - 0.00096 19.6 0.0 0.0016 18.9 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KLO03766.1 - 0.001 19.5 0.0 0.0018 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KLO03766.1 - 0.0015 19.1 0.0 0.0019 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KLO03766.1 - 0.0041 17.5 0.0 0.0062 16.9 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KLO03766.1 - 0.0047 17.1 0.0 0.0051 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KLO03766.1 - 0.0089 15.8 0.1 0.009 15.8 0.1 1.3 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KLO03766.1 - 0.013 16.1 0.0 0.043 14.3 0.0 1.7 1 1 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 KLO03766.1 - 0.024 14.7 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO03766.1 - 0.027 14.4 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 KLO03766.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KLO03766.1 - 0.028 14.2 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KLO03766.1 - 0.029 14.3 0.0 0.03 14.2 0.0 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KLO03766.1 - 0.042 13.8 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KLO03766.1 - 0.056 13.7 0.0 0.065 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KLO03766.1 - 0.058 13.4 0.0 0.061 13.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KLO03766.1 - 0.083 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KLO03766.1 - 0.093 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA12 PF10443.9 KLO03766.1 - 0.12 11.1 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein NTPase_1 PF03266.15 KLO03766.1 - 0.15 12.0 0.2 0.15 12.0 0.2 1.3 1 1 0 1 1 1 0 NTPase AAA_PrkA PF08298.11 KLO03766.1 - 0.2 10.6 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain Parvo_NS1 PF01057.17 KLO03766.1 - 0.21 10.6 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Arabinose_trans PF04602.12 KLO03774.1 - 0.0066 15.3 0.6 0.0069 15.3 0.6 1.0 1 0 0 1 1 1 1 Mycobacterial cell wall arabinan synthesis protein RAB3GAP2_N PF14655.6 KLO03775.1 - 0.1 11.8 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SDP_N PF12278.8 KLO03780.1 - 0.14 12.3 0.4 0.17 12.0 0.4 1.2 1 0 0 1 1 1 0 Sex determination protein N terminal OrsD PF12013.8 KLO03783.1 - 0.00091 19.7 5.1 0.0023 18.3 0.5 3.2 2 2 1 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D DEAD PF00270.29 KLO03791.1 - 3e-06 27.1 0.0 1.2e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KLO03791.1 - 0.036 14.3 0.0 0.12 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain T4SS-DNA_transf PF02534.14 KLO03791.1 - 0.086 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer ResIII PF04851.15 KLO03791.1 - 0.19 11.7 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Integrase_H2C2 PF17921.1 KLO03793.1 - 2.3e-07 30.8 0.4 3.3e-07 30.3 0.4 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_lysozyme PF00959.19 KLO03795.1 - 0.089 13.3 0.7 33 5.0 0.0 2.9 3 0 0 3 3 3 0 Phage lysozyme Kri1 PF05178.12 KLO03795.1 - 0.13 12.9 3.7 0.64 10.6 0.3 2.4 2 0 0 2 2 2 0 KRI1-like family SRA PF18491.1 KLO03795.1 - 0.85 9.7 5.1 2.1 8.5 0.7 2.5 2 1 1 3 3 3 0 SET and RING associated domain DUF3080 PF11279.8 KLO03795.1 - 0.96 8.6 3.8 2.4 7.3 3.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3080) gag_pre-integrs PF13976.6 KLO03799.1 - 2.5e-05 24.1 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF2884 PF11101.8 KLO03800.1 - 0.016 14.7 0.3 0.027 14.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Peptidase_M50 PF02163.22 KLO03801.1 - 6.6e-05 22.3 0.0 0.00061 19.1 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M50 AAA_13 PF13166.6 KLO03803.1 - 0.0021 16.8 4.2 0.0041 15.8 4.2 1.5 1 0 0 1 1 1 1 AAA domain Lipoprotein_7 PF01540.16 KLO03803.1 - 0.0022 17.4 5.5 0.0036 16.6 5.5 1.2 1 0 0 1 1 1 1 Adhesin lipoprotein MbeD_MobD PF04899.12 KLO03803.1 - 0.014 15.5 0.6 0.043 13.9 0.6 1.9 1 0 0 1 1 1 0 MbeD/MobD like CLZ PF16526.5 KLO03803.1 - 0.14 12.5 10.0 1.8 9.0 0.3 3.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cep57_MT_bd PF06657.13 KLO03803.1 - 0.4 11.2 14.3 0.39 11.2 0.2 3.7 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 FapA PF03961.13 KLO03803.1 - 0.58 8.7 6.6 0.94 8.0 6.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A HAUS-augmin3 PF14932.6 KLO03803.1 - 1.5 8.4 11.4 6.7 6.2 9.8 2.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 FliD_C PF07195.12 KLO03803.1 - 2.3 7.6 12.4 6.7 6.1 5.9 3.2 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Laminin_II PF06009.12 KLO03803.1 - 7.6 6.6 13.4 1.7 8.7 2.0 2.3 2 1 1 3 3 3 0 Laminin Domain II UPF0242 PF06785.11 KLO03803.1 - 7.6 6.6 17.3 9.8 6.2 13.0 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus NuiA PF07924.11 KLO03804.1 - 0.021 15.2 0.4 0.036 14.5 0.2 1.4 1 1 0 1 1 1 0 Nuclease A inhibitor-like protein DUF1676 PF07898.13 KLO03804.1 - 0.38 10.8 1.1 0.45 10.5 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) GPI-anchored PF10342.9 KLO03806.1 - 8.5e-05 23.2 0.1 0.0004 21.1 0.1 1.8 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KLO03806.1 - 0.071 12.9 0.1 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3944 PF13099.6 KLO03809.1 - 0.15 12.0 0.8 0.66 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) Ribonuc_red_sm PF00268.21 KLO03816.1 - 4.7e-115 383.8 2.2 5.8e-115 383.6 2.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Big_3_4 PF13754.6 KLO03819.1 - 0.1 12.3 0.1 0.35 10.6 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function DEAD PF00270.29 KLO03820.1 - 4.5e-08 33.1 0.0 5.8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO03820.1 - 0.00074 19.6 0.0 0.0039 17.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 KLO03820.1 - 0.037 12.8 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DUF853 PF05872.12 KLO03820.1 - 0.062 11.9 0.0 0.068 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 KLO03820.1 - 0.18 12.0 0.2 23 5.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain HTH_Tnp_Tc5 PF03221.16 KLO03823.1 - 1.4e-12 47.4 0.0 2.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF4790 PF16037.5 KLO03825.1 - 0.13 12.7 0.9 0.66 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4790) Astro_capsid_p PF12226.8 KLO03825.1 - 2.3 7.3 10.2 3 6.9 10.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 KLO03825.1 - 4.5 5.4 10.1 5.3 5.2 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Plavaka PF18759.1 KLO03827.1 - 2.8e-75 253.6 0.0 3.3e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF2535 PF10751.9 KLO03827.1 - 0.016 15.7 0.0 0.14 12.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2535) Patatin PF01734.22 KLO03828.1 - 5.7e-09 36.4 1.6 6.1e-09 36.4 1.6 1.0 1 0 0 1 1 1 1 Patatin-like phospholipase PTS_EIIC_2 PF13303.6 KLO03828.1 - 0.076 12.0 0.9 0.081 11.9 0.9 1.0 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Patatin PF01734.22 KLO03829.1 - 7.7e-09 36.0 0.2 1.5e-08 35.1 0.1 1.4 1 1 0 1 1 1 1 Patatin-like phospholipase MazG PF03819.17 KLO03831.1 - 0.0062 16.7 1.0 0.035 14.3 0.1 2.2 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain 1-cysPrx_C PF10417.9 KLO03831.1 - 0.078 12.8 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin CWC25 PF12542.8 KLO03831.1 - 5.2 8.0 7.9 0.82 10.6 3.4 2.0 2 1 1 3 3 3 0 Pre-mRNA splicing factor Patatin PF01734.22 KLO03832.1 - 5.8e-09 36.4 0.9 6.3e-09 36.3 0.9 1.0 1 0 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.22 KLO03833.1 - 1.4e-09 38.5 0.2 7.3e-09 36.1 0.2 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase DUF2981 PF11200.8 KLO03834.1 - 0.18 11.5 0.0 0.21 11.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Nha1_C PF08619.10 KLO03837.1 - 0.45 9.7 4.7 0.73 9.0 4.7 1.4 1 1 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Sua5_yciO_yrdC PF01300.18 KLO03843.1 - 0.13 11.7 0.5 0.22 11.0 0.5 1.4 1 0 0 1 1 1 0 Telomere recombination 2OG-FeII_Oxy_4 PF13661.6 KLO03844.1 - 2.6e-31 108.2 0.0 4.4e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ofd1_CTDD PF10637.9 KLO03844.1 - 2.4e-16 59.8 0.0 1.6e-12 47.3 0.0 2.6 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.6 KLO03844.1 - 1.2e-15 58.2 0.0 1.9e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_L18 PF17135.4 KLO03847.1 - 9.2e-51 171.9 0.5 1.1e-50 171.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e p450 PF00067.22 KLO03856.1 - 0.008 15.0 0.0 0.0091 14.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF5063 PF16702.5 KLO03859.1 - 0.01 16.2 0.1 0.012 16.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) Retrotran_gag_2 PF14223.6 KLO03861.1 - 1.8e-14 53.6 0.1 2.5e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KLO03861.1 - 9.3e-07 28.4 0.1 1.6e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KLO03861.1 - 0.0076 16.0 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KLO03861.1 - 0.029 14.1 0.4 0.049 13.4 0.4 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger HTH_Tnp_Tc5 PF03221.16 KLO03863.1 - 7.9e-11 41.8 0.0 2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KLO03863.1 - 0.007 16.0 0.4 0.06 13.0 0.2 2.2 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 KLO03863.1 - 0.089 12.7 0.2 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 MarR family Cro PF09048.10 KLO03863.1 - 0.12 12.4 0.1 0.82 9.8 0.0 2.2 2 0 0 2 2 2 0 Cro HTH_Tnp_4 PF13613.6 KLO03863.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Integrase_H2C2 PF17921.1 KLO03868.1 - 1.3e-05 25.2 0.5 2e-05 24.6 0.5 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain SHP PF03579.13 KLO03869.1 - 1.2 9.1 7.7 1.5 8.8 0.3 2.6 3 0 0 3 3 3 0 Small hydrophobic protein PC_rep PF01851.22 KLO03874.1 - 7.7e-31 105.0 17.0 4.7e-07 29.9 0.1 8.0 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KLO03874.1 - 4.9e-10 39.7 1.7 0.00027 21.2 0.0 4.4 1 1 4 5 5 5 5 HEAT repeats HEAT PF02985.22 KLO03874.1 - 0.00089 19.3 0.3 0.91 10.0 0.2 3.5 3 0 0 3 3 3 2 HEAT repeat CTK3_C PF12350.8 KLO03878.1 - 2.2e-26 91.8 4.3 3.4e-26 91.2 4.3 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus DUF4554 PF15091.6 KLO03881.1 - 3.5 6.4 4.3 7.8 5.3 4.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4554) CTK3_C PF12350.8 KLO03890.1 - 1.4e-25 89.2 6.0 2.4e-25 88.5 6.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.8 KLO03890.1 - 0.0088 16.0 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Helitron_like_N PF14214.6 KLO03892.1 - 1.4e-20 74.3 0.0 1.5e-20 74.2 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus CobA_CobO_BtuR PF02572.15 KLO03893.1 - 0.022 15.0 0.0 0.029 14.7 0.0 1.1 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP zf-NF-X1 PF01422.17 KLO03893.1 - 1.3 9.1 5.8 2.8 8.1 2.4 2.4 2 0 0 2 2 2 0 NF-X1 type zinc finger KDZ PF18758.1 KLO03894.1 - 5.8e-60 202.7 0.0 8.1e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase RNase_T PF00929.24 KLO03896.1 - 3.1e-11 44.1 0.0 5.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 KLO03896.1 - 1.5e-05 25.0 0.1 0.00021 21.4 0.1 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 KLO03896.1 - 0.072 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Spt5-NGN PF03439.13 KLO03897.1 - 7.1e-13 48.3 0.0 3.5e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section DUF501 PF04417.12 KLO03897.1 - 0.2 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF501) CDC45 PF02724.14 KLO03897.1 - 0.54 8.5 1.9 0.62 8.3 1.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KLO03897.1 - 1.5 6.8 11.7 1.9 6.5 11.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KLO03897.1 - 1.9 7.6 11.4 2.4 7.2 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 KLO03897.1 - 2.2 7.5 6.3 2.7 7.2 6.3 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KLO03897.1 - 4.3 5.4 8.2 5.3 5.1 8.2 1.0 1 0 0 1 1 1 0 Nop14-like family UPF0158 PF03682.13 KLO03899.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) Retrotran_gag_2 PF14223.6 KLO03903.1 - 1.7e-09 37.5 0.0 2.8e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KLO03903.1 - 0.003 17.3 0.9 0.0059 16.3 0.9 1.5 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_4 PF14392.6 KLO03903.1 - 0.14 11.9 0.3 2.4 8.0 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF755 PF05501.11 KLO03903.1 - 0.15 12.3 6.1 0.22 11.8 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.9 KLO03903.1 - 1 9.0 14.3 1.4 8.4 14.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ezh2_MCSS PF18600.1 KLO03904.1 - 0.017 14.8 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 MCSS domain Ribonuc_red_lgC PF02867.15 KLO03909.1 - 0.00028 19.6 0.4 0.00043 18.9 0.4 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain G-gamma PF00631.22 KLO03909.1 - 0.14 12.2 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 GGL domain SIR4_SID PF16991.5 KLO03912.1 - 0.079 13.0 0.5 0.079 13.0 0.5 2.0 2 0 0 2 2 2 0 Sir4 SID domain Rsc14 PF08586.10 KLO03912.1 - 0.094 13.5 0.7 0.094 13.5 0.7 2.4 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Pneumo_att_G PF05539.11 KLO03912.1 - 0.61 9.6 2.1 0.91 9.1 2.1 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF908 PF06012.12 KLO03912.1 - 2.5 7.4 8.7 0.11 11.8 1.4 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DUF2316 PF10078.9 KLO03918.1 - 0.07 13.4 0.2 0.23 11.7 0.2 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF1961 PF09224.11 KLO03918.1 - 0.16 11.3 0.2 0.39 10.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1961) PEP-utilisers_N PF05524.13 KLO03918.1 - 0.34 11.1 2.3 1.2 9.3 0.5 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal F-box PF00646.33 KLO03919.1 - 0.0003 20.6 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KLO03919.1 - 0.0023 17.8 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KLO03919.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 F-box-like TMEM191C PF15194.6 KLO03921.1 - 0.054 13.7 0.0 0.065 13.4 0.0 1.1 1 0 0 1 1 1 0 TMEM191C family LprI PF07007.12 KLO03922.1 - 0.06 14.0 0.9 0.1 13.3 0.5 1.5 1 1 0 1 1 1 0 Lysozyme inhibitor LprI DUF812 PF05667.11 KLO03922.1 - 0.11 11.4 3.8 0.15 10.9 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) WD40 PF00400.32 KLO03924.1 - 7.4e-12 45.6 7.0 2.2e-09 37.8 0.2 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO03924.1 - 0.015 15.6 0.0 0.084 13.2 0.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KLO03924.1 - 0.025 13.2 0.5 0.65 8.6 0.1 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 RT_RNaseH_2 PF17919.1 KLO03925.1 - 7.9e-18 64.3 0.0 1.9e-17 63.1 0.0 1.6 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KLO03925.1 - 2.1e-15 56.9 0.0 3.5e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KLO03925.1 - 4.6e-08 32.8 0.1 7.8e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HMG_box_2 PF09011.10 KLO03926.1 - 7.1e-07 29.7 0.0 1.4e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KLO03926.1 - 5e-05 23.6 0.0 9.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Hexapep PF00132.24 KLO03928.1 - 0.061 13.1 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) WD40 PF00400.32 KLO03932.1 - 6e-12 45.9 4.6 2e-08 34.7 0.0 3.9 3 1 1 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO03932.1 - 6.7e-07 29.5 0.0 0.00027 21.2 0.0 2.3 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KLO03932.1 - 0.0023 17.3 0.0 0.29 10.4 0.0 2.0 1 1 1 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIIC_delta PF12657.7 KLO03932.1 - 0.024 14.6 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term SARS_X4 PF08779.10 KLO03932.1 - 0.13 12.5 0.2 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 SARS coronavirus X4 like DUF4221 PF13970.6 KLO03932.1 - 0.26 10.8 0.0 0.29 10.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) HpuA PF16960.5 KLO03936.1 - 0.19 10.8 0.1 0.27 10.3 0.1 1.2 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter DUF3123 PF11321.8 KLO03936.1 - 0.26 12.0 1.6 0.61 10.8 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) RVP_2 PF08284.11 KLO03938.1 - 8.2e-09 35.3 0.0 1.2e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KLO03938.1 - 2.1e-08 34.6 0.0 3.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KLO03938.1 - 1.1e-05 26.0 0.0 2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KLO03938.1 - 1.5e-05 24.8 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease HEPN_SAV_6107 PF18726.1 KLO03940.1 - 0.14 12.7 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 SAV_6107-like HEPN Alpha-amylase PF00128.24 KLO03941.1 - 3.4e-79 266.9 3.5 4.3e-79 266.5 3.5 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KLO03941.1 - 5.7e-05 22.4 0.0 8.1e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain PIF1 PF05970.14 KLO03942.1 - 1.5e-09 37.5 0.7 4.2e-07 29.5 0.1 2.4 1 1 1 2 2 2 2 PIF1-like helicase Pkinase_fungal PF17667.1 KLO03946.1 - 1.3e-25 90.1 0.0 1.5e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase DUF4964 PF16334.5 KLO03946.1 - 0.019 14.5 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) EFP_N PF08207.12 KLO03946.1 - 0.23 11.5 0.4 0.47 10.5 0.2 1.7 1 1 1 2 2 2 0 Elongation factor P (EF-P) KOW-like domain DUF3630 PF12305.8 KLO03948.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) Integrase_H2C2 PF17921.1 KLO03949.1 - 1.3e-15 57.2 0.4 2.4e-15 56.4 0.4 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 KLO03949.1 - 1.2e-08 35.4 0.0 2.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KLO03949.1 - 3.1e-08 33.4 0.0 6.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KLO03949.1 - 1.4e-06 28.8 0.0 4.2e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KLO03949.1 - 5.9e-05 22.9 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 KLO03949.1 - 0.0011 19.2 0.1 0.0083 16.3 0.1 2.3 2 0 0 2 2 2 1 H2C2 zinc finger HMG_box_2 PF09011.10 KLO03950.1 - 0.00013 22.5 0.2 0.00022 21.8 0.2 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KLO03950.1 - 0.00022 21.6 0.1 0.00042 20.7 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Hyr1 PF15789.5 KLO03951.1 - 1.5 8.4 4.0 20 4.8 1.5 2.4 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 DUF5111 PF17138.4 KLO03952.1 - 0.036 13.9 0.6 0.044 13.6 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5111) WD40 PF00400.32 KLO03953.1 - 2.9e-16 59.5 0.6 8.4e-11 42.3 0.1 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO03953.1 - 3.3e-05 24.1 0.0 0.0013 19.0 0.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO03953.1 - 0.024 13.6 0.0 0.029 13.4 0.0 1.3 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HbrB PF08539.11 KLO03956.1 - 4.2e-06 26.9 0.0 6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 HbrB-like KDZ PF18758.1 KLO03959.1 - 5.6e-46 156.9 1.8 7.7e-46 156.5 1.8 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase PHD PF00628.29 KLO03960.1 - 0.017 15.0 2.7 0.065 13.1 0.3 2.4 2 0 0 2 2 2 0 PHD-finger BAH PF01426.18 KLO03960.1 - 0.023 14.6 4.0 0.12 12.2 4.1 2.1 1 1 0 1 1 1 0 BAH domain PHD_4 PF16866.5 KLO03960.1 - 0.15 12.1 1.4 4.4 7.5 0.1 2.4 2 0 0 2 2 2 0 PHD-finger Complex1_LYR PF05347.15 KLO03963.1 - 1.7e-11 44.0 2.4 2.2e-11 43.6 2.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KLO03963.1 - 0.12 13.0 2.4 1.3 9.7 0.2 2.1 1 1 1 2 2 2 0 Complex1_LYR-like PQQ_2 PF13360.6 KLO03964.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 1 1 0 1 1 1 0 PQQ-like domain Mago-bind PF09282.10 KLO03965.1 - 0.37 10.7 10.0 0.46 10.4 1.0 4.0 4 0 0 4 4 4 0 Mago binding Aldo_ket_red PF00248.21 KLO03966.1 - 9.8e-30 103.7 0.0 4.3e-29 101.7 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family DUF374 PF04028.13 KLO03966.1 - 0.017 14.6 0.1 0.67 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF374) HTH_23 PF13384.6 KLO03966.1 - 0.15 11.9 0.0 0.4 10.5 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain SbmA_BacA PF05992.12 KLO03966.1 - 0.19 11.1 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 SbmA/BacA-like family CAP_N PF01213.19 KLO03966.1 - 0.28 10.6 1.1 0.36 10.3 1.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GGDEF_2 PF17853.1 KLO03967.1 - 0.081 13.2 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 GGDEF-like domain PNTB PF02233.16 KLO03971.1 - 1.6 7.5 28.6 6.2 5.6 28.6 1.7 1 1 0 1 1 1 0 NAD(P) transhydrogenase beta subunit Nop14 PF04147.12 KLO03972.1 - 6.4 4.9 13.1 8.2 4.5 13.1 1.2 1 0 0 1 1 1 0 Nop14-like family gag_pre-integrs PF13976.6 KLO03975.1 - 3.8e-08 33.1 0.0 5.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain OrsD PF12013.8 KLO03978.1 - 2.7e-06 27.8 2.3 6.4e-06 26.6 0.0 2.4 2 1 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D DM PF00751.18 KLO03978.1 - 0.017 15.0 0.9 0.017 15.0 0.9 2.3 2 0 0 2 2 2 0 DM DNA binding domain zf-C2H2_8 PF15909.5 KLO03978.1 - 0.044 14.1 2.8 0.15 12.4 1.4 2.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KLO03978.1 - 0.75 10.2 8.4 64 4.0 0.0 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KLO03978.1 - 6 8.0 21.9 0.67 10.9 0.3 5.6 5 1 0 5 5 5 0 C2H2-type zinc finger F-box PF00646.33 KLO03982.1 - 0.0012 18.6 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KLO03982.1 - 0.0078 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 F-box CTK3 PF12243.8 KLO03986.1 - 6.2e-23 81.1 0.0 6.8e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 DUF3437 PF11919.8 KLO03986.1 - 0.0088 15.9 0.0 0.0089 15.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) CENP-B_N PF04218.13 KLO03989.1 - 3.1e-05 23.5 0.0 5.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 KLO03989.1 - 0.0021 18.6 0.1 0.0044 17.6 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 KLO03989.1 - 0.0031 17.5 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KLO03989.1 - 0.075 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 KLO03989.1 - 0.082 12.7 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain Skp1_POZ PF03931.15 KLO03990.1 - 1.6e-13 50.6 0.2 5.6e-13 48.9 0.0 1.9 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 KLO03990.1 - 3.3e-12 46.3 0.0 7.3e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain BTB PF00651.31 KLO03990.1 - 0.11 12.8 0.0 0.55 10.5 0.0 1.9 1 1 0 1 1 1 0 BTB/POZ domain DUF4218 PF13960.6 KLO03990.1 - 0.13 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) T5orf172 PF10544.9 KLO03991.1 - 0.052 14.1 0.1 0.082 13.5 0.1 1.5 1 1 0 1 1 1 0 T5orf172 domain MutS_II PF05188.17 KLO03991.1 - 0.15 12.3 0.3 0.3 11.4 0.0 1.6 2 0 0 2 2 2 0 MutS domain II Transposase_24 PF03004.14 KLO03993.1 - 0.0079 16.3 0.5 0.026 14.6 0.5 1.9 1 0 0 1 1 1 1 Plant transposase (Ptta/En/Spm family) GrpE PF01025.19 KLO03995.1 - 0.076 12.7 0.0 0.087 12.5 0.0 1.0 1 0 0 1 1 1 0 GrpE Transposase_21 PF02992.14 KLO03996.1 - 1.1e-06 28.0 0.0 1.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 KLO03996.1 - 0.0019 17.5 0.0 0.0023 17.2 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF1451 PF07295.11 KLO03996.1 - 0.11 12.5 0.0 0.7 9.9 0.0 1.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF4218 PF13960.6 KLO03997.1 - 7.4e-06 25.6 0.1 1e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) TC1 PF15063.6 KLO03998.1 - 0.052 13.4 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Thyroid cancer protein 1 Glucodextran_B PF09136.10 KLO03998.1 - 0.059 13.7 0.0 0.079 13.3 0.0 1.2 1 0 0 1 1 1 0 Glucodextranase, domain B Skp1_POZ PF03931.15 KLO03999.1 - 4e-15 55.7 0.3 6e-15 55.2 0.3 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 KLO03999.1 - 6.9e-15 54.9 0.1 1.3e-14 54.1 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain BTB PF00651.31 KLO03999.1 - 0.052 13.8 0.1 0.39 11.0 0.1 2.1 1 1 0 1 1 1 0 BTB/POZ domain KDZ PF18758.1 KLO04000.1 - 5.6e-10 39.2 0.1 9.5e-10 38.5 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Transposase_21 PF02992.14 KLO04001.1 - 6.2e-06 25.6 0.0 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 KLO04001.1 - 0.045 13.0 0.1 0.079 12.2 0.1 1.3 1 0 0 1 1 1 0 Plavaka transposase DUF4218 PF13960.6 KLO04001.1 - 0.19 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Bac_luciferase PF00296.20 KLO04003.1 - 0.15 11.4 0.0 0.17 11.3 0.0 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase Asp_protease_2 PF13650.6 KLO04004.1 - 1.7e-06 28.6 0.0 3.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KLO04004.1 - 0.0001 22.8 0.0 0.00036 21.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DDE_1 PF03184.19 KLO04005.1 - 6.4e-41 139.9 0.0 9.4e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KLO04005.1 - 1.1e-08 34.9 0.0 3.5e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF1249 PF06853.12 KLO04014.1 - 0.039 14.0 0.3 0.075 13.1 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1249) DEC-1_N PF04625.13 KLO04015.1 - 7 5.5 16.2 1.6 7.7 12.5 1.6 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DDE_3 PF13358.6 KLO04016.1 - 4e-08 33.1 0.0 6.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 KLO04016.1 - 4.9e-06 26.2 0.1 2e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 KLO04016.1 - 2.8e-05 23.7 0.0 7.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1 PF01527.20 KLO04016.1 - 0.0025 18.1 0.0 0.0062 16.8 0.0 1.6 1 0 0 1 1 1 1 Transposase HTH_WhiA PF02650.14 KLO04016.1 - 0.006 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 WhiA C-terminal HTH domain HTH_32 PF13565.6 KLO04016.1 - 0.029 15.0 0.1 0.14 12.7 0.1 2.0 1 1 1 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.6 KLO04016.1 - 0.058 13.4 0.0 0.6 10.2 0.0 2.3 2 1 0 2 2 2 0 Winged helix-turn helix FAM167 PF11652.8 KLO04016.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 FAM167 HTH_7 PF02796.15 KLO04016.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Foamy_virus_ENV PF03408.14 KLO04017.1 - 0.22 9.3 0.3 0.25 9.1 0.3 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein gag-asp_proteas PF13975.6 KLO04018.1 - 0.033 14.8 0.0 0.038 14.6 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KLO04018.1 - 0.047 14.3 0.0 0.062 13.9 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease DUF1769 PF08588.10 KLO04018.1 - 0.095 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Tau95 PF09734.9 KLO04019.1 - 0.45 11.3 4.1 0.21 12.4 0.6 2.1 2 1 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Plavaka PF18759.1 KLO04020.1 - 2.3e-72 244.0 0.2 3.1e-72 243.6 0.2 1.2 1 0 0 1 1 1 1 Plavaka transposase Glyco_hydro_16 PF00722.21 KLO04028.1 - 9.7e-12 44.7 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 EamA PF00892.20 KLO04028.1 - 0.1 12.8 2.2 0.19 11.9 0.0 2.2 3 0 0 3 3 3 0 EamA-like transporter family F-box PF00646.33 KLO04031.1 - 0.065 13.1 0.7 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 F-box domain Macoilin PF09726.9 KLO04032.1 - 0.64 8.5 5.2 0.63 8.5 4.8 1.3 1 1 0 1 1 1 0 Macoilin family RR_TM4-6 PF06459.12 KLO04032.1 - 6.7 6.4 9.2 11 5.8 9.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MLVIN_C PF18697.1 KLO04035.1 - 0.026 14.6 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF2686 PF10887.8 KLO04038.1 - 0.065 12.2 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) P19Arf_N PF07392.12 KLO04039.1 - 0.077 13.5 4.9 12 6.4 2.6 3.2 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus RNase_H PF00075.24 KLO04041.1 - 0.007 16.5 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 KLO04041.1 - 0.019 15.7 0.0 0.039 14.7 0.0 1.7 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase zf_Rg PF17915.1 KLO04041.1 - 0.13 11.7 0.3 0.52 9.8 0.1 2.0 2 0 0 2 2 2 0 Reverse gyrase zinc finger Rrn6 PF10214.9 KLO04041.1 - 0.14 10.6 0.1 0.16 10.4 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PAM2 PF07145.15 KLO04043.1 - 0.022 14.4 1.2 0.066 12.9 1.2 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region RPA_interact_M PF14767.6 KLO04043.1 - 0.88 10.2 5.0 0.23 12.1 1.6 1.7 2 0 0 2 2 2 0 Replication protein A interacting middle BTB PF00651.31 KLO04044.1 - 0.075 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain HTH_Tnp_Tc5 PF03221.16 KLO04048.1 - 2.6e-09 36.9 0.0 6.5e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Sigma70_r4 PF04545.16 KLO04048.1 - 0.0023 17.4 0.2 0.015 14.8 0.1 2.4 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_24 PF13412.6 KLO04048.1 - 0.0027 17.2 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KLO04048.1 - 0.005 16.6 0.6 0.46 10.3 0.0 3.4 3 1 1 4 4 4 1 Homeodomain-like domain Phage_terminase PF10668.9 KLO04048.1 - 0.0089 16.0 0.2 0.032 14.2 0.2 1.9 2 0 0 2 2 2 1 Phage terminase small subunit HTH_Tnp_4 PF13613.6 KLO04048.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.22 KLO04048.1 - 0.061 13.3 0.0 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 MarR family Sigma70_r4_2 PF08281.12 KLO04048.1 - 0.093 12.4 0.0 6 6.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_7 PF02796.15 KLO04048.1 - 0.097 12.8 0.1 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Crp_2 PF13545.6 KLO04048.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 1 0 Crp-like helix-turn-helix domain HTH_32 PF13565.6 KLO04048.1 - 0.11 13.2 0.1 0.24 12.1 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KLO04048.1 - 0.11 12.7 0.0 1.1 9.5 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 KLO04048.1 - 0.13 12.1 0.0 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.6 KLO04048.1 - 0.19 11.5 1.0 1 9.2 0.1 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 KLO04048.1 - 0.2 11.5 0.0 5.6 6.8 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain Sigma70_ECF PF07638.11 KLO04051.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 ECF sigma factor RAB3GAP2_N PF14655.6 KLO04052.1 - 0.0065 15.8 0.0 0.0088 15.3 0.0 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus SARS_X4 PF08779.10 KLO04052.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 SARS coronavirus X4 like Skp1 PF01466.19 KLO04053.1 - 4e-14 52.4 0.0 7.2e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KLO04053.1 - 2.6e-12 46.7 0.0 4.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 KLO04053.1 - 0.074 13.3 0.1 0.44 10.8 0.1 2.1 1 1 0 1 1 1 0 BTB/POZ domain Spt5_N PF11942.8 KLO04056.1 - 0.004 18.1 0.7 0.0048 17.8 0.7 1.1 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal MCC-bdg_PDZ PF10506.9 KLO04058.1 - 0.013 15.5 0.6 0.032 14.2 0.6 1.6 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome CENP-F_leu_zip PF10473.9 KLO04058.1 - 0.032 14.3 4.8 0.049 13.7 4.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OrsD PF12013.8 KLO04060.1 - 0.055 13.9 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Xan_ur_permease PF00860.20 KLO04061.1 - 3.6e-26 91.8 13.2 6.5e-21 74.5 7.5 2.0 2 0 0 2 2 2 2 Permease family ECF_trnsprt PF12822.7 KLO04061.1 - 0.00028 21.0 1.4 0.00028 21.0 1.4 2.4 1 1 0 2 2 2 1 ECF transporter, substrate-specific component Acyl-ACP_TE PF01643.17 KLO04063.1 - 0.14 11.4 0.2 0.24 10.7 0.2 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase Sigma70_ner PF04546.13 KLO04063.1 - 0.22 11.4 6.9 0.41 10.5 6.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 KLO04063.1 - 0.56 9.5 3.5 1 8.6 3.5 1.3 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.32 KLO04064.1 - 2.3e-08 34.5 5.3 3.7e-05 24.4 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO04064.1 - 0.00031 21.0 0.0 0.014 15.7 0.0 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KLO04064.1 - 0.032 14.2 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term SH3_19 PF18597.1 KLO04064.1 - 0.089 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain Coronavirus_5 PF05528.11 KLO04064.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Coronavirus gene 5 protein CECR6_TMEM121 PF14997.6 KLO04065.1 - 0.094 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 CECR6/TMEM121 family Drc1-Sld2 PF11719.8 KLO04066.1 - 0.62 9.5 10.0 1.1 8.7 10.0 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein SURF2 PF05477.11 KLO04066.1 - 1.6 8.4 7.7 3.2 7.4 7.7 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF2722 PF10846.8 KLO04066.1 - 2 7.3 7.9 3 6.7 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) KDZ PF18758.1 KLO04068.1 - 7.7e-55 185.9 0.6 1.6e-54 184.9 0.6 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO04068.1 - 7.3e-31 106.5 1.1 1.4e-30 105.6 1.1 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO04068.1 - 2.1e-05 24.6 0.3 4.7e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KLO04069.1 - 8.9e-31 106.2 0.1 1.9e-30 105.2 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO04069.1 - 7.9e-08 32.4 0.1 3e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases KOW PF00467.29 KLO04073.1 - 1.4e-06 28.0 20.3 0.091 12.8 1.2 5.0 4 0 0 4 4 4 4 KOW motif AP_endonuc_2 PF01261.24 KLO04076.1 - 0.041 13.3 0.1 0.047 13.1 0.1 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Helicase_C PF00271.31 KLO04077.1 - 4.4e-09 36.7 0.0 5.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4026 PF13218.6 KLO04077.1 - 0.025 13.6 0.0 0.36 9.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4026) DEAD PF00270.29 KLO04078.1 - 0.004 16.9 0.0 0.0048 16.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase PYC_OADA PF02436.18 KLO04080.1 - 0.064 13.0 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Conserved carboxylase domain CHD5 PF04420.14 KLO04082.1 - 0.23 11.3 1.4 0.24 11.3 1.4 1.1 1 0 0 1 1 1 0 CHD5-like protein WD40 PF00400.32 KLO04086.1 - 4.9e-06 27.2 6.0 0.013 16.4 0.1 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO04086.1 - 0.00078 19.7 0.1 0.25 11.7 0.3 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KLO04086.1 - 0.013 14.5 0.1 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Coatomer WD associated region SH3_19 PF18597.1 KLO04086.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain HTH_Tnp_Tc5 PF03221.16 KLO04087.1 - 2.4e-12 46.7 0.1 7.2e-12 45.2 0.1 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KLO04087.1 - 9.9e-07 28.3 0.5 6.9e-06 25.6 0.1 2.5 2 1 1 3 3 3 1 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.16 KLO04087.1 - 0.027 14.0 0.0 0.33 10.5 0.0 2.4 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_23 PF13384.6 KLO04087.1 - 0.054 13.3 0.0 0.47 10.3 0.0 2.5 2 1 0 2 2 2 0 Homeodomain-like domain HTH_3 PF01381.22 KLO04087.1 - 0.065 13.3 0.1 0.66 10.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_Crp_2 PF13545.6 KLO04087.1 - 0.069 13.1 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain WD40 PF00400.32 KLO04090.1 - 1.7e-10 41.3 3.4 2e-05 25.3 0.4 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO04090.1 - 0.0004 20.6 0.1 0.13 12.5 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PepSY_TM PF03929.16 KLO04090.1 - 0.025 14.2 0.1 0.071 12.8 0.1 1.7 2 0 0 2 2 2 0 PepSY-associated TM region DUF808 PF05661.12 KLO04090.1 - 0.032 13.3 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) RAB3GAP2_N PF14655.6 KLO04090.1 - 0.034 13.4 0.0 6.4 5.9 0.0 3.0 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BTB PF00651.31 KLO04091.1 - 6.7e-05 23.1 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain XkdW PF09636.10 KLO04093.1 - 0.11 12.6 0.1 9.2 6.4 0.0 2.1 2 0 0 2 2 2 0 XkdW protein zf-MYND PF01753.18 KLO04095.1 - 3.9e-06 26.9 14.9 1.1e-05 25.4 14.9 1.8 1 0 0 1 1 1 1 MYND finger hemP PF10636.9 KLO04095.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Hemin uptake protein hemP zf-C6H2 PF15801.5 KLO04095.1 - 0.64 10.4 14.6 1.3 9.4 14.6 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding COG7 PF10191.9 KLO04099.1 - 0.018 13.3 0.0 0.027 12.7 0.0 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Flavi_glycop_C PF02832.16 KLO04100.1 - 0.022 14.9 0.1 0.049 13.8 0.1 1.5 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain TFIIA PF03153.13 KLO04100.1 - 0.14 12.1 8.1 0.2 11.6 8.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIF1 PF05970.14 KLO04102.1 - 3.2e-09 36.5 0.1 5.7e-09 35.6 0.1 1.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KLO04102.1 - 9.7e-09 35.2 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO04102.1 - 2.4e-07 31.2 0.0 3.3e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KLO04102.1 - 0.00074 19.9 0.1 0.0017 18.8 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 KLO04102.1 - 0.0009 19.1 0.1 0.091 12.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_24 PF13479.6 KLO04102.1 - 0.0011 18.8 0.0 0.0035 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KLO04102.1 - 0.012 15.6 0.1 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KLO04102.1 - 0.017 14.4 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KLO04102.1 - 0.02 15.2 0.4 0.065 13.5 0.4 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KLO04102.1 - 0.03 14.2 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 KLO04102.1 - 0.09 12.5 0.1 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 KLO04102.1 - 0.1 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.6 KLO04102.1 - 0.11 12.3 0.1 0.15 11.8 0.0 1.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KLO04102.1 - 0.16 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KLO04102.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Mago-bind PF09282.10 KLO04103.1 - 1.7 8.6 3.9 1.1 9.2 0.6 2.5 3 0 0 3 3 3 0 Mago binding Msap1 PF17077.5 KLO04105.1 - 0.12 11.6 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Mitotic spindle associated protein SHE1 Pertus-S5-tox PF09276.10 KLO04105.1 - 0.17 11.9 0.2 0.75 9.9 0.0 1.9 1 1 1 2 2 2 0 Pertussis toxin S5 subunit PBP_sp32 PF07222.12 KLO04108.1 - 9.7 5.6 8.2 0.62 9.5 0.5 2.3 2 1 1 3 3 3 0 Proacrosin binding protein sp32 COP23 PF14218.6 KLO04112.1 - 0.054 13.3 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Circadian oscillating protein COP23 CxC2 PF18803.1 KLO04113.1 - 6.7e-32 109.8 0.0 1e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO04113.1 - 0.0018 18.4 0.1 0.0031 17.6 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Stc1 PF12898.7 KLO04113.1 - 0.027 15.0 0.6 0.08 13.5 0.2 1.8 2 0 0 2 2 2 0 Stc1 domain zf-UBR PF02207.20 KLO04113.1 - 0.35 11.1 8.2 0.14 12.3 1.2 2.7 2 1 1 3 3 3 0 Putative zinc finger in N-recognin (UBR box) KDZ PF18758.1 KLO04114.1 - 3.6e-58 196.8 0.9 4.7e-58 196.4 0.9 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase zf-BED PF02892.15 KLO04117.1 - 7.2 6.7 6.3 0.86 9.7 0.1 2.5 3 1 0 3 3 3 0 BED zinc finger F-box-like PF12937.7 KLO04118.1 - 5.4e-06 26.2 1.0 3.3e-05 23.7 0.3 2.6 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 KLO04118.1 - 0.015 15.1 2.6 17 5.2 0.0 4.3 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 KLO04118.1 - 0.069 13.6 7.3 20 5.7 0.2 5.0 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) PSY3 PF16836.5 KLO04118.1 - 0.17 11.4 0.0 0.41 10.1 0.0 1.7 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description F-box PF00646.33 KLO04118.1 - 6.1 6.8 8.2 36 4.4 0.1 4.0 3 1 0 3 3 3 0 F-box domain F-box PF00646.33 KLO04119.1 - 0.082 12.8 1.1 0.36 10.8 0.0 2.6 2 0 0 2 2 2 0 F-box domain Fmp27_GFWDK PF10347.9 KLO04119.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Plavaka PF18759.1 KLO04121.1 - 5.9e-121 403.7 0.0 7.8e-121 403.3 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Phage_integrase PF00589.22 KLO04126.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family SPG48 PF14764.6 KLO04127.1 - 0.088 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking zf-RING_UBOX PF13445.6 KLO04129.1 - 3.5e-06 26.9 0.0 6.3e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 RING-type zinc-finger She9_MDM33 PF05546.11 KLO04129.1 - 0.00032 20.6 0.3 0.00035 20.4 0.3 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family zf-Nse PF11789.8 KLO04129.1 - 0.0016 18.2 1.3 0.0028 17.4 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit MAP7 PF05672.11 KLO04129.1 - 0.02 14.6 4.6 0.029 14.1 4.6 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family zf-C3HC4_2 PF13923.6 KLO04129.1 - 0.19 11.6 0.3 0.19 11.6 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ZapB PF06005.12 KLO04129.1 - 0.72 10.3 6.3 1.4 9.5 6.3 1.4 1 0 0 1 1 1 0 Cell division protein ZapB PAM2 PF07145.15 KLO04131.1 - 0.23 11.2 5.3 0.069 12.9 1.7 2.1 2 0 0 2 2 2 0 Ataxin-2 C-terminal region PTP_N PF12453.8 KLO04131.1 - 0.28 10.9 1.9 0.7 9.7 0.6 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal NACHT PF05729.12 KLO04132.1 - 3.9e-07 30.1 0.0 7.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KLO04132.1 - 5.1e-07 30.0 0.0 2.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO04132.1 - 7.2e-06 26.5 0.1 4.9e-05 23.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KLO04132.1 - 0.0084 16.0 0.1 0.036 14.0 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KLO04132.1 - 0.0087 15.3 0.0 0.027 13.7 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain PPV_E1_C PF00519.17 KLO04132.1 - 0.015 14.2 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RNA_helicase PF00910.22 KLO04132.1 - 0.015 15.7 0.0 0.044 14.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KLO04132.1 - 0.016 15.6 0.0 0.4 11.1 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) BB_PF PF18063.1 KLO04132.1 - 0.097 12.2 0.1 0.42 10.2 0.1 2.0 2 0 0 2 2 2 0 Beta barrel Pore-forming domain AAA_19 PF13245.6 KLO04132.1 - 0.18 12.1 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SET PF00856.28 KLO04133.1 - 8.8e-11 42.5 0.0 2.2e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 SET domain SAF PF08666.12 KLO04133.1 - 0.12 13.0 0.0 17 6.1 0.0 2.6 2 0 0 2 2 2 0 SAF domain NACHT PF05729.12 KLO04134.1 - 6.3e-05 22.9 0.0 0.00032 20.7 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO04134.1 - 0.001 19.5 0.0 0.0047 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Parvo_NS1 PF01057.17 KLO04134.1 - 0.093 11.8 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF664 PF04978.12 KLO04138.1 - 0.12 12.8 0.1 0.69 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF664) T3RM_EcoP15I_C PF18273.1 KLO04142.1 - 0.083 13.2 0.1 1.4 9.3 0.0 2.7 3 0 0 3 3 3 0 Type III R-M EcoP15I C-terminal domain FANCA_interact PF15751.5 KLO04145.1 - 0.059 13.9 2.1 0.17 12.4 2.1 1.7 1 0 0 1 1 1 0 FAAP20 FANCA interaction domain HTH_33 PF13592.6 KLO04146.1 - 5.2e-08 32.4 0.1 6.3e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KLO04146.1 - 1.8e-05 24.9 0.2 2.4e-05 24.5 0.2 1.3 1 1 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.11 KLO04146.1 - 0.0049 15.9 0.1 0.0056 15.7 0.1 1.0 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain DDE_3 PF13358.6 KLO04147.1 - 1.2e-08 34.8 0.0 1.3e-08 34.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO04148.1 - 5.4e-07 29.5 0.0 6.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF998 PF06197.13 KLO04150.1 - 0.066 12.8 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) OCC1 PF15506.6 KLO04152.1 - 0.1 12.8 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 OCC1 family TPR_10 PF13374.6 KLO04153.1 - 1.6e-15 56.4 16.5 0.0041 16.9 0.1 10.7 11 1 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 KLO04153.1 - 8.4e-07 29.2 23.5 1.7 9.0 0.2 10.6 9 4 3 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 KLO04153.1 - 0.0023 18.2 0.0 27 5.4 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KLO04153.1 - 0.0026 17.9 1.9 54 4.4 0.0 7.0 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KLO04153.1 - 0.0059 16.6 14.9 0.95 9.7 0.0 8.1 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 KLO04153.1 - 0.015 16.0 24.2 63 4.8 0.0 9.7 9 2 2 11 11 9 0 Tetratricopeptide repeat AIP3 PF03915.13 KLO04153.1 - 0.018 14.1 1.5 0.038 13.1 0.1 2.2 2 1 0 2 2 2 0 Actin interacting protein 3 TPR_1 PF00515.28 KLO04153.1 - 0.026 14.3 9.2 8.5 6.4 0.0 7.0 10 0 0 10 10 10 0 Tetratricopeptide repeat Cas_DxTHG PF09455.10 KLO04153.1 - 0.036 13.7 0.0 5.5 6.5 0.1 2.9 2 1 1 3 3 3 0 CRISPR-associated (Cas) DxTHG family Osmo_CC PF08946.10 KLO04153.1 - 0.18 12.1 1.2 28 5.0 0.0 3.7 3 0 0 3 3 3 0 Osmosensory transporter coiled coil CRISPR_Cse2 PF09485.10 KLO04153.1 - 0.42 11.1 8.6 12 6.5 0.1 4.8 4 1 1 5 5 5 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF4404 PF14357.6 KLO04153.1 - 2.7 8.7 5.3 22 5.8 0.2 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF4404) DUF4164 PF13747.6 KLO04153.1 - 6.4 7.1 16.9 3.6 7.9 0.3 6.2 7 1 1 8 8 8 0 Domain of unknown function (DUF4164) BCIP PF13862.6 KLO04155.1 - 4.2e-11 43.0 0.1 5.8e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Chorion_3 PF05387.11 KLO04155.1 - 0.084 12.5 0.0 0.084 12.5 0.0 1.0 1 0 0 1 1 1 0 Chorion family 3 HMG_box PF00505.19 KLO04159.1 - 2.9e-05 24.4 0.1 5.1e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO04159.1 - 0.0017 18.9 0.0 0.0033 18.0 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain DHC PF09626.10 KLO04165.1 - 0.0011 19.8 0.2 0.0033 18.3 0.0 1.7 2 0 0 2 2 2 1 Dihaem cytochrome c zf-MYND PF01753.18 KLO04170.1 - 1.3e-05 25.1 5.1 1.3e-05 25.1 5.1 1.9 1 1 0 1 1 1 1 MYND finger DNA_pol_A_exo1 PF01612.20 KLO04171.1 - 8.9e-17 61.4 0.0 1.2e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease Caskin-Pro-rich PF16907.5 KLO04174.1 - 0.93 10.1 4.7 0.35 11.4 1.9 1.7 2 0 0 2 2 2 0 Proline rich region of Caskin proteins DEAD PF00270.29 KLO04178.1 - 4.6e-07 29.8 0.0 5.4e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO04178.1 - 9.1e-05 22.5 0.0 0.00013 22.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rhamno_transf PF11316.8 KLO04180.1 - 0.053 12.9 0.2 0.11 11.8 0.2 1.5 1 1 0 1 1 1 0 Putative rhamnosyl transferase DUF2256 PF10013.9 KLO04181.1 - 7.1 6.8 6.0 1.7e+02 2.4 0.0 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) BCIP PF13862.6 KLO04183.1 - 4.2e-11 43.0 0.1 5.8e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Chorion_3 PF05387.11 KLO04183.1 - 0.084 12.5 0.0 0.084 12.5 0.0 1.0 1 0 0 1 1 1 0 Chorion family 3 KDZ PF18758.1 KLO04185.1 - 2e-55 187.9 0.0 3.3e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO04185.1 - 1.1e-30 106.0 0.1 2.3e-30 104.9 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO04185.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases HcyBio PF01837.16 KLO04187.1 - 0.19 10.5 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Homocysteine biosynthesis enzyme, sulfur-incorporation NUDE_C PF04880.13 KLO04188.1 - 1 9.8 7.2 1 9.8 7.2 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF3787 PF12655.7 KLO04189.1 - 0.025 14.5 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) ADSL_C PF10397.9 KLO04189.1 - 0.028 15.0 0.3 0.11 13.1 0.3 1.9 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminus Helicase_C PF00271.31 KLO04191.1 - 3.7e-15 56.2 0.0 7.3e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KLO04191.1 - 0.00015 21.1 2.3 0.00074 18.8 2.3 1.9 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SLC12 PF03522.15 KLO04191.1 - 0.066 12.2 1.6 0.096 11.7 1.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RNA_pol_Rpc4 PF05132.14 KLO04191.1 - 0.29 11.6 4.5 0.4 11.1 4.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 KLO04191.1 - 0.32 11.2 3.3 1 9.5 3.5 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PHD PF00628.29 KLO04192.1 - 0.00023 21.0 4.4 0.00057 19.7 1.8 2.5 2 0 0 2 2 2 1 PHD-finger BAH PF01426.18 KLO04192.1 - 0.019 14.8 0.1 0.27 11.1 0.1 2.6 1 1 0 1 1 1 0 BAH domain KdpC PF02669.15 KLO04192.1 - 0.026 14.4 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 K+-transporting ATPase, c chain zf-LITAF-like PF10601.9 KLO04192.1 - 2.8 8.3 8.3 3.9 7.8 1.1 2.9 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain WD40 PF00400.32 KLO04195.1 - 1.7e-08 35.0 5.0 7.4e-05 23.4 0.0 4.8 4 1 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO04195.1 - 1e-05 25.7 0.0 0.032 14.5 0.0 3.7 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KLO04195.1 - 0.0038 16.6 0.1 1.1 8.4 0.0 2.6 2 1 1 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF5598 PF18127.1 KLO04202.1 - 0.18 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5598) Herpes_UL95 PF03038.14 KLO04203.1 - 0.19 10.8 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 UL95 family AbiEii PF08843.11 KLO04208.1 - 0.15 12.0 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system zf-MYND PF01753.18 KLO04209.1 - 7.9e-07 29.1 7.5 1.8e-06 27.9 7.5 1.7 1 0 0 1 1 1 1 MYND finger Pex14_N PF04695.13 KLO04210.1 - 0.058 14.1 0.1 0.084 13.5 0.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sulfotransfer_1 PF00685.27 KLO04210.1 - 0.07 12.6 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain HbrB PF08539.11 KLO04210.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 HbrB-like CxC2 PF18803.1 KLO04211.1 - 2.5e-30 104.8 2.0 2.8e-30 104.6 0.1 1.8 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO04211.1 - 0.0039 17.3 0.1 0.0077 16.4 0.1 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases zf-UBR PF02207.20 KLO04211.1 - 0.64 10.2 10.4 0.21 11.8 3.3 2.8 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) KDZ PF18758.1 KLO04212.1 - 3.5e-57 193.6 0.0 4.1e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Transposase_21 PF02992.14 KLO04216.1 - 1e-08 34.7 0.0 2.2e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 KLO04216.1 - 3.3e-05 23.5 0.1 7.3e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Plavaka PF18759.1 KLO04216.1 - 0.0004 19.7 0.0 0.00079 18.7 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_10 PF16588.5 KLO04220.1 - 0.01 15.5 1.9 0.019 14.7 1.9 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC PF00098.23 KLO04220.1 - 0.13 12.4 2.5 0.24 11.6 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle gag_pre-integrs PF13976.6 KLO04221.1 - 6.2e-11 42.0 0.2 8.5e-11 41.6 0.2 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain gag_pre-integrs PF13976.6 KLO04223.1 - 7.4e-08 32.1 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-C2H2_10 PF16588.5 KLO04224.1 - 0.003 17.2 0.5 0.003 17.2 0.5 1.9 2 0 0 2 2 2 1 C2H2 zinc-finger Retrotran_gag_2 PF14223.6 KLO04225.1 - 6.2e-07 29.2 0.0 7.8e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type CxC2 PF18803.1 KLO04227.1 - 4e-29 100.9 0.1 5.4e-29 100.5 0.1 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO04227.1 - 0.056 13.6 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases MSA-2c PF12238.8 KLO04228.1 - 1.3 9.0 5.8 2.2 8.2 5.8 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c BTB PF00651.31 KLO04229.1 - 8.5e-06 26.0 0.0 5e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO04230.1 - 4e-05 23.8 0.0 4.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Chromo PF00385.24 KLO04232.1 - 2.4e-07 30.6 0.1 2.6e-07 30.4 0.1 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Patatin PF01734.22 KLO04234.1 - 0.00011 22.5 0.2 0.022 14.9 0.1 2.2 1 1 0 2 2 2 2 Patatin-like phospholipase PIG-X PF08320.12 KLO04237.1 - 0.058 13.3 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 PIG-X / PBN1 F-box-like PF12937.7 KLO04238.1 - 1.4e-08 34.4 0.7 1.4e-08 34.4 0.7 2.8 3 1 0 3 3 3 1 F-box-like AT_hook PF02178.19 KLO04239.1 - 0.8 9.8 10.5 3.4 7.9 10.5 2.2 1 0 0 1 1 1 0 AT hook motif HSP70 PF00012.20 KLO04240.1 - 8.8e-79 265.3 0.1 1.1e-78 265.0 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KLO04240.1 - 1.5e-05 24.0 0.0 2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.10 KLO04240.1 - 0.022 13.8 0.1 0.44 9.5 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain GIT_SHD PF08518.11 KLO04240.1 - 0.073 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT Hydantoinase_A PF01968.18 KLO04240.1 - 0.15 11.3 0.1 0.43 9.8 0.2 1.7 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase HTH_33 PF13592.6 KLO04241.1 - 6.4e-08 32.1 0.1 7.8e-08 31.9 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KLO04241.1 - 2e-05 24.8 0.1 2.6e-05 24.4 0.1 1.3 1 1 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.11 KLO04241.1 - 0.006 15.6 0.0 0.0068 15.4 0.0 1.0 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain DDE_3 PF13358.6 KLO04242.1 - 1.2e-08 34.8 0.0 1.3e-08 34.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO04243.1 - 2.4e-07 30.6 0.0 3.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 KLO04243.1 - 0.039 12.9 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain CxC2 PF18803.1 KLO04244.1 - 0.024 14.8 0.1 0.047 13.9 0.1 1.5 2 0 0 2 2 2 0 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KLO04245.1 - 3.2e-19 69.5 0.3 3.4e-19 69.4 0.3 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Phage_integrase PF00589.22 KLO04247.1 - 0.002 18.0 0.0 0.0071 16.2 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family DUF3736 PF12540.8 KLO04253.1 - 0.028 14.5 0.5 0.039 14.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) WD40 PF00400.32 KLO04253.1 - 0.047 14.6 0.1 16 6.6 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Plavaka PF18759.1 KLO04254.1 - 2.2e-05 23.9 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF4218 PF13960.6 KLO04254.1 - 0.0025 17.4 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Pkinase PF00069.25 KLO04255.1 - 3.3e-11 43.1 0.0 5.8e-10 39.0 0.0 2.3 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO04255.1 - 0.0027 17.0 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase VP9 PF09625.10 KLO04255.1 - 0.05 13.8 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 VP9 protein Kdo PF06293.14 KLO04255.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEC-1_N PF04625.13 KLO04260.1 - 0.055 12.5 7.7 0.3 10.0 8.7 1.7 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Apolipoprotein PF01442.18 KLO04260.1 - 0.061 13.2 1.2 0.11 12.4 0.9 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HrcA PF01628.21 KLO04260.1 - 0.18 11.7 0.2 0.24 11.3 0.2 1.1 1 0 0 1 1 1 0 HrcA protein C terminal domain KDZ PF18758.1 KLO04261.1 - 3.5e-50 170.7 1.2 5.2e-50 170.1 1.2 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO04261.1 - 8.7e-29 99.8 0.6 2.1e-28 98.6 0.0 2.0 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO04261.1 - 6.7e-07 29.4 0.0 2.5e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KLO04261.1 - 9.8e-06 25.4 3.6 1.2e-05 25.1 0.0 2.7 3 0 0 3 3 3 1 CxC3 like cysteine cluster associated with KDZ transposases Abi_2 PF07751.11 KLO04263.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Abi-like protein DUF3912 PF13051.6 KLO04264.1 - 0.00016 21.9 0.1 0.0017 18.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) KOW PF00467.29 KLO04264.1 - 0.00025 20.9 3.2 0.012 15.6 0.1 2.5 2 0 0 2 2 2 2 KOW motif zf-MYND PF01753.18 KLO04272.1 - 9.3e-07 28.8 3.5 9.3e-07 28.8 3.5 1.8 2 0 0 2 2 2 1 MYND finger F-box-like PF12937.7 KLO04278.1 - 1.3e-07 31.4 0.1 1.1e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO04278.1 - 0.0014 18.4 0.6 0.005 16.7 0.6 2.0 1 0 0 1 1 1 1 F-box domain Guanylin PF02058.15 KLO04278.1 - 0.073 13.6 0.0 2.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Guanylin precursor HTH_Tnp_Tc5 PF03221.16 KLO04279.1 - 7.5e-06 25.9 0.0 2.5e-05 24.2 0.0 1.9 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KLO04280.1 - 9.5e-22 77.5 0.0 1.4e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3656 PF12392.8 KLO04280.1 - 0.083 13.5 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Collagenase CTK3 PF12243.8 KLO04283.1 - 6.2e-23 81.1 0.0 6.8e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 DUF3437 PF11919.8 KLO04283.1 - 0.0088 15.9 0.0 0.0089 15.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Dimer_Tnp_hAT PF05699.14 KLO04286.1 - 2e-18 65.9 0.1 4.6e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region p450 PF00067.22 KLO04286.1 - 9e-17 61.0 0.0 1.5e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 CARD_2 PF16739.5 KLO04286.1 - 0.04 13.9 0.0 2.9 8.0 0.0 2.8 2 0 0 2 2 2 0 Caspase recruitment domain WD40 PF00400.32 KLO04289.1 - 1.6e-06 28.7 3.9 0.17 12.8 0.0 4.7 3 1 1 4 4 4 2 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 KLO04289.1 - 0.019 14.3 0.1 0.22 10.7 0.1 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BBS2_Mid PF14783.6 KLO04289.1 - 0.071 13.1 0.0 1.3 9.1 0.0 2.7 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Dfp1_Him1_M PF08630.10 KLO04290.1 - 0.096 12.9 0.1 0.096 12.9 0.1 2.3 3 0 0 3 3 3 0 Dfp1/Him1, central region DUF5327 PF17261.2 KLO04290.1 - 1.4 9.7 5.2 0.74 10.6 0.6 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5327) Chromo PF00385.24 KLO04291.1 - 7.9e-12 44.9 3.8 1.3e-11 44.2 3.8 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-RING_2 PF13639.6 KLO04292.1 - 3.3e-09 36.9 1.9 4.2e-08 33.4 0.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KLO04292.1 - 1.7e-07 30.9 0.2 3.1e-05 23.6 0.1 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KLO04292.1 - 2.1e-07 30.7 5.4 3.3e-07 30.0 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KLO04292.1 - 2.7e-07 30.8 1.3 5.9e-07 29.7 0.3 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KLO04292.1 - 2.7e-06 27.2 0.6 2.6e-05 24.0 0.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO04292.1 - 3.4e-05 23.8 3.4 0.00016 21.6 0.7 2.6 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KLO04292.1 - 5.6e-05 22.9 0.9 5.6e-05 22.9 0.9 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KLO04292.1 - 8e-05 22.5 0.5 0.00027 20.8 0.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KLO04292.1 - 0.0038 17.0 1.5 0.01 15.7 0.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KLO04292.1 - 0.0082 16.2 0.5 0.017 15.2 0.1 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Tyrosinase PF00264.20 KLO04292.1 - 0.095 13.0 0.2 0.2 11.9 0.2 1.5 1 0 0 1 1 1 0 Common central domain of tyrosinase GET2 PF08690.10 KLO04292.1 - 0.11 12.1 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 zf-C3HC4_4 PF15227.6 KLO04292.1 - 0.18 12.0 2.4 0.18 12.0 0.4 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KLO04292.1 - 0.37 10.5 4.7 0.075 12.7 0.8 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Nop14 PF04147.12 KLO04301.1 - 0.0017 16.7 29.3 0.0018 16.6 29.3 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 KLO04301.1 - 0.03 13.8 28.2 0.033 13.6 28.2 1.1 1 0 0 1 1 1 0 SDA1 Drc1-Sld2 PF11719.8 KLO04301.1 - 0.035 13.7 9.7 0.04 13.5 9.7 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein BUD22 PF09073.10 KLO04301.1 - 0.052 12.9 25.0 0.059 12.7 25.0 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KLO04301.1 - 0.11 10.8 20.6 0.13 10.5 20.6 1.1 1 0 0 1 1 1 0 CDC45-like protein HGTP_anticodon2 PF12745.7 KLO04301.1 - 0.11 11.9 2.3 0.14 11.6 2.3 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Mpp10 PF04006.12 KLO04301.1 - 0.11 10.9 22.1 0.13 10.7 22.1 1.1 1 0 0 1 1 1 0 Mpp10 protein SpoIIIAH PF12685.7 KLO04301.1 - 0.12 12.2 7.5 0.13 12.0 7.5 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein ATAD4 PF15321.6 KLO04301.1 - 0.27 12.6 3.8 0.43 11.9 3.8 1.5 1 1 0 1 1 1 0 ATPase family AAA domain containing 4 RNA_pol_Rpc4 PF05132.14 KLO04301.1 - 1.2 9.5 5.2 1.6 9.2 5.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 KLO04301.1 - 2.1 7.2 5.9 2.3 7.1 5.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Lin-8 PF03353.15 KLO04301.1 - 2.4 7.7 11.2 2.8 7.4 11.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SAPS PF04499.15 KLO04301.1 - 3.1 6.5 9.5 3.1 6.5 9.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 KLO04301.1 - 4.6 5.9 5.9 5.1 5.8 5.9 1.0 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.12 KLO04301.1 - 4.7 5.7 31.4 5.3 5.5 31.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pes-10 PF07149.11 KLO04301.1 - 6 5.8 25.1 6.9 5.6 25.1 1.1 1 0 0 1 1 1 0 Pes-10 Zip PF02535.22 KLO04301.1 - 9.1 5.4 6.1 11 5.1 6.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ferritin PF00210.24 KLO04307.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Ferritin-like domain NACHT PF05729.12 KLO04308.1 - 1.8e-10 41.0 0.0 2.3e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KLO04308.1 - 7.3e-07 29.5 0.0 9.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO04308.1 - 3.8e-06 27.4 0.0 7.2e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KLO04308.1 - 1.3e-05 25.6 0.1 9.4e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KLO04308.1 - 0.00017 20.9 0.7 0.00062 19.0 0.7 1.8 1 1 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 KLO04308.1 - 0.00051 19.8 0.3 0.00063 19.5 0.3 1.4 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KLO04308.1 - 0.00056 19.9 0.0 0.0007 19.6 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KLO04308.1 - 0.0023 18.4 0.2 0.0046 17.5 0.2 1.5 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 KLO04308.1 - 0.0024 18.4 0.1 0.0066 17.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KLO04308.1 - 0.0086 16.0 0.3 0.015 15.2 0.3 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase Parvo_NS1 PF01057.17 KLO04308.1 - 0.0089 15.1 0.4 0.015 14.5 0.4 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PIF1 PF05970.14 KLO04308.1 - 0.035 13.3 0.1 0.061 12.5 0.1 1.4 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 KLO04308.1 - 0.035 14.5 0.2 0.066 13.6 0.1 1.6 1 1 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 KLO04308.1 - 0.048 12.9 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain PhoH PF02562.16 KLO04308.1 - 0.048 13.1 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 KLO04308.1 - 0.064 13.0 0.3 0.2 11.4 0.2 1.8 1 1 1 2 2 2 0 IstB-like ATP binding protein DnaB_C PF03796.15 KLO04308.1 - 0.078 12.3 0.0 0.098 12.0 0.0 1.2 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.9 KLO04308.1 - 0.08 12.2 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KLO04308.1 - 0.082 12.6 0.3 0.11 12.3 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KLO04308.1 - 0.087 13.2 0.2 0.15 12.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KLO04308.1 - 0.14 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_33 PF13671.6 KLO04308.1 - 0.2 11.8 0.2 0.23 11.6 0.2 1.4 1 1 0 1 1 1 0 AAA domain Goodbye PF17109.5 KLO04309.1 - 0.094 13.2 0.0 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain ubiquitin PF00240.23 KLO04315.1 - 6.1e-29 99.6 0.4 7.5e-29 99.3 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KLO04315.1 - 7.7e-13 48.1 0.2 9.7e-13 47.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KLO04315.1 - 9.1e-06 26.0 0.1 3.8e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KLO04315.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.3 1 1 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KLO04315.1 - 0.0037 17.4 0.0 0.0088 16.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KLO04315.1 - 0.0052 17.1 0.1 0.015 15.6 0.1 1.6 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 KLO04315.1 - 0.011 16.2 0.1 0.014 15.9 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PseudoU_synth_1 PF01416.20 KLO04316.1 - 1.2e-09 38.5 0.0 1.3e-07 32.0 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase THRAP3_BCLAF1 PF15440.6 KLO04317.1 - 0.038 13.0 3.1 0.061 12.3 3.1 1.3 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF2368 PF10166.9 KLO04319.1 - 0.0036 16.9 0.0 0.099 12.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2368) Chromo PF00385.24 KLO04320.1 - 4.4e-08 32.9 0.1 7.3e-08 32.2 0.0 1.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KLO04323.1 - 9.1e-07 29.2 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO04323.1 - 1.4e-06 28.2 0.0 3.7e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO04323.1 - 0.0012 18.9 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KLO04323.1 - 0.02 14.4 0.1 0.043 13.3 0.1 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain THDPS_M PF14789.6 KLO04324.1 - 0.07 13.2 0.1 0.27 11.4 0.1 2.0 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase middle WD40 PF00400.32 KLO04326.1 - 2.2e-07 31.4 13.4 0.00023 21.9 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO04326.1 - 3.1e-05 24.2 0.0 0.059 13.7 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SH3_19 PF18597.1 KLO04326.1 - 0.16 11.9 0.1 0.74 9.7 0.1 2.1 2 0 0 2 2 2 0 Myosin X N-terminal SH3 domain TFIIIC_delta PF12657.7 KLO04326.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term CcdA PF07362.12 KLO04329.1 - 0.061 13.8 2.5 0.17 12.3 2.5 1.8 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA TnpB_IS66 PF05717.13 KLO04329.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 IS66 Orf2 like protein DDE_1 PF03184.19 KLO04330.1 - 6.6e-12 45.4 0.0 1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease STE3 PF02076.15 KLO04332.1 - 7.7e-70 235.4 9.4 8.8e-70 235.2 9.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor APG6_N PF17675.1 KLO04333.1 - 0.0083 16.6 3.1 0.0091 16.5 3.1 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF327 PF03885.13 KLO04333.1 - 0.034 14.1 2.7 0.051 13.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF327) MMS22L_C PF14911.6 KLO04333.1 - 0.061 12.4 0.0 0.072 12.2 0.0 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Cir_N PF10197.9 KLO04333.1 - 6.9 6.9 10.5 0.6 10.4 3.6 2.4 1 1 1 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR Plavaka PF18759.1 KLO04335.1 - 1.8e-65 221.3 0.0 2.1e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF4254 PF14063.6 KLO04337.1 - 0.071 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Peptidase_C48 PF02902.19 KLO04341.1 - 1e-14 54.9 1.6 1.6e-14 54.3 1.6 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GWT1 PF06423.12 KLO04345.1 - 0.15 12.1 3.9 0.18 11.9 3.4 1.6 1 1 0 1 1 1 0 GWT1 DEAD PF00270.29 KLO04348.1 - 6.2e-16 58.7 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO04348.1 - 1.1e-09 38.6 0.0 1.6e-08 34.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO04348.1 - 5.4e-09 36.3 0.0 1.4e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 KLO04348.1 - 9.8e-05 21.3 0.0 0.00014 20.8 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer DUF1908 PF08926.11 KLO04349.1 - 0.011 14.8 0.9 0.012 14.8 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Hormone_1 PF00103.20 KLO04349.1 - 0.073 12.8 0.7 1.2 8.8 0.1 2.1 1 1 1 2 2 2 0 Somatotropin hormone family DnaJ-X PF14308.6 KLO04350.1 - 3.6e-36 124.6 0.1 1.7e-34 119.1 0.1 2.1 1 1 0 1 1 1 1 X-domain of DnaJ-containing Pkinase PF00069.25 KLO04355.1 - 2.2e-14 53.5 0.0 5.1e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO04355.1 - 1.1e-12 47.8 0.0 1.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ax_dynein_light PF10211.9 KLO04355.1 - 0.0052 16.7 0.7 0.0089 16.0 0.7 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain APH PF01636.23 KLO04355.1 - 0.032 14.1 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3860 PF12976.7 KLO04355.1 - 0.12 12.4 0.2 0.46 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) DUF5558 PF17713.1 KLO04356.1 - 0.43 11.0 7.8 0.97 9.8 7.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5558) zf-C2H2_10 PF16588.5 KLO04357.1 - 0.023 14.4 6.0 0.038 13.7 6.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC PF00098.23 KLO04357.1 - 0.047 13.8 2.6 0.079 13.1 2.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KLO04357.1 - 0.068 12.9 0.6 0.12 12.2 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KLO04357.1 - 0.15 11.9 1.1 0.15 11.9 1.1 1.6 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.17 KLO04360.1 - 1.4e-05 25.3 0.5 2.3e-05 24.6 0.5 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Rhodopsin_N PF10413.9 KLO04365.1 - 0.099 12.5 0.6 0.25 11.2 0.7 1.5 2 0 0 2 2 2 0 Amino terminal of the G-protein receptor rhodopsin Peptidase_U49 PF10463.9 KLO04365.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase U49 PmbA_TldD PF01523.16 KLO04367.1 - 0.1 12.4 1.3 0.18 11.6 1.3 1.3 1 0 0 1 1 1 0 Putative modulator of DNA gyrase RPA_C PF08784.11 KLO04368.1 - 0.0047 17.6 2.2 0.023 15.4 0.0 2.3 1 1 0 2 2 2 1 Replication protein A C terminal T5orf172 PF10544.9 KLO04368.1 - 0.035 14.7 1.0 0.16 12.5 0.1 2.1 1 1 1 2 2 2 0 T5orf172 domain Phage_Nu1 PF07471.12 KLO04372.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Phage DNA packaging protein Nu1 Chromo PF00385.24 KLO04374.1 - 6.4e-08 32.4 0.0 8.5e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain KDZ PF18758.1 KLO04377.1 - 1.2e-73 247.4 0.6 2.6e-73 246.3 0.6 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Oxygenase-NA PF09859.9 KLO04377.1 - 0.064 12.8 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Ecotin PF03974.13 KLO04379.1 - 0.022 14.8 0.0 0.068 13.2 0.0 1.7 2 0 0 2 2 2 0 Ecotin Antigen_Bd37 PF11641.8 KLO04379.1 - 0.097 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Arm-DNA-bind_2 PF12167.8 KLO04379.1 - 0.12 12.3 1.4 15 5.6 0.0 2.9 3 0 0 3 3 3 0 Arm DNA-binding domain Chromo PF00385.24 KLO04381.1 - 3.4e-07 30.1 0.0 3.9e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Plavaka PF18759.1 KLO04383.1 - 4.8e-54 183.8 0.0 9.3e-43 146.7 0.1 2.2 1 1 1 2 2 2 2 Plavaka transposase NB-ARC PF00931.22 KLO04386.1 - 9.6e-06 25.0 0.1 2.5e-05 23.6 0.0 1.8 2 0 0 2 2 1 1 NB-ARC domain NACHT PF05729.12 KLO04386.1 - 1.3e-05 25.1 0.0 3.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO04386.1 - 0.0001 22.8 0.0 0.00049 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KLO04386.1 - 0.00019 21.7 0.0 0.0011 19.2 0.0 2.3 3 0 0 3 3 2 1 AAA domain APS_kinase PF01583.20 KLO04386.1 - 0.00056 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ResIII PF04851.15 KLO04386.1 - 0.0013 18.8 0.0 0.0034 17.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.17 KLO04386.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA PF00004.29 KLO04386.1 - 0.0043 17.5 0.0 0.012 16.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KLO04386.1 - 0.005 17.4 0.0 0.03 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KLO04386.1 - 0.0067 16.2 0.0 0.021 14.6 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KLO04386.1 - 0.0073 15.6 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.27 KLO04386.1 - 0.0075 16.8 0.0 0.025 15.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter T2SSE PF00437.20 KLO04386.1 - 0.01 14.9 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 KLO04386.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KLO04386.1 - 0.016 15.0 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KLO04386.1 - 0.023 15.0 0.0 0.084 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KLO04386.1 - 0.026 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SRP54 PF00448.22 KLO04386.1 - 0.039 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 KLO04386.1 - 0.041 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 KLO04386.1 - 0.047 13.2 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 KLO04386.1 - 0.047 13.8 0.1 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KLO04386.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KLO04386.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KLO04386.1 - 0.069 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KLO04386.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC NTPase_1 PF03266.15 KLO04386.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NTPase Ploopntkinase3 PF18751.1 KLO04386.1 - 0.091 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ATPase_2 PF01637.18 KLO04386.1 - 0.1 12.5 0.4 0.33 10.8 0.0 2.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KLO04386.1 - 0.13 12.3 0.1 0.64 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 KLO04386.1 - 0.14 12.2 0.2 0.52 10.4 0.0 2.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.6 KLO04386.1 - 0.15 12.5 2.2 0.51 10.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KLO04386.1 - 0.28 11.6 0.2 0.28 11.6 0.2 2.6 3 1 1 4 4 1 0 AAA domain gag-asp_proteas PF13975.6 KLO04391.1 - 8e-07 29.5 0.2 2.2e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KLO04391.1 - 7.1e-05 23.4 0.1 0.00017 22.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Herpes_ORF11 PF04797.13 KLO04391.1 - 0.0084 15.0 0.1 0.012 14.4 0.1 1.2 1 0 0 1 1 1 1 Herpesvirus dUTPase protein RVP PF00077.20 KLO04391.1 - 0.091 13.1 0.1 0.25 11.6 0.1 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 KLO04391.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 2 0 0 2 2 2 0 Aspartyl protease RET_CLD1 PF17756.1 KLO04392.1 - 0.0019 18.5 0.2 0.0059 16.9 0.2 1.9 1 1 1 2 2 2 1 RET Cadherin like domain 1 WD40 PF00400.32 KLO04396.1 - 3.4e-60 198.6 31.4 5.4e-10 39.7 0.2 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO04396.1 - 9.6e-25 86.7 1.1 0.004 17.4 0.0 7.8 2 1 6 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO04396.1 - 5.8e-10 38.6 3.7 1.9 7.4 0.1 6.3 1 1 4 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KLO04396.1 - 2.3e-07 30.9 0.1 6.9e-05 22.8 0.2 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KLO04396.1 - 6.3e-06 26.0 1.4 4.3 7.4 0.0 5.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KLO04396.1 - 0.00012 21.5 4.3 6.3 6.0 0.1 5.1 2 2 3 5 5 5 3 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KLO04396.1 - 0.0004 18.8 0.0 0.094 11.0 0.0 2.4 1 1 2 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KLO04396.1 - 0.0018 17.7 0.0 2.8 7.2 0.0 3.5 2 2 1 4 4 4 1 WD40-like domain Proteasome_A_N PF10584.9 KLO04396.1 - 4.1 7.2 5.6 36 4.2 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature SnoaL_2 PF12680.7 KLO04398.1 - 0.0066 17.1 0.0 0.0096 16.5 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain ADH_zinc_N PF00107.26 KLO04399.1 - 1.6e-14 54.0 0.0 2.8e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO04399.1 - 1.3e-09 39.3 0.0 2.8e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO04399.1 - 0.00048 20.0 0.3 0.0066 16.3 0.1 2.2 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KLO04399.1 - 0.019 14.8 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ERGIC_N PF13850.6 KLO04400.1 - 0.14 12.5 0.0 1.3 9.4 0.0 2.4 1 1 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MULE PF10551.9 KLO04401.1 - 3e-11 43.6 0.0 2e-10 40.9 0.0 2.4 2 0 0 2 2 2 1 MULE transposase domain HTH_53 PF18606.1 KLO04401.1 - 0.15 11.7 0.1 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain zf-CCHC_2 PF13696.6 KLO04402.1 - 0.0011 18.7 5.4 0.0016 18.2 5.4 1.3 1 0 0 1 1 1 1 Zinc knuckle PBP1_TM PF14812.6 KLO04402.1 - 0.017 15.5 4.9 0.041 14.2 4.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF3g PF12353.8 KLO04402.1 - 0.034 14.6 1.1 0.065 13.6 1.1 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G FAM176 PF14851.6 KLO04402.1 - 0.13 11.9 1.1 0.28 10.8 1.1 1.5 1 0 0 1 1 1 0 FAM176 family Nucleo_P87 PF07267.11 KLO04402.1 - 7.4 5.3 6.8 9.6 4.9 6.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Neprosin_AP PF14365.6 KLO04404.1 - 0.034 14.6 0.2 0.089 13.3 0.0 1.8 2 0 0 2 2 2 0 Neprosin activation peptide zf-RVT PF13966.6 KLO04410.1 - 0.00022 21.8 0.0 0.00034 21.3 0.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase p450 PF00067.22 KLO04414.1 - 3.5e-64 217.3 0.0 4.5e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO04415.1 - 6e-69 233.0 0.0 7.6e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PseudoU_synth_1 PF01416.20 KLO04417.1 - 1.2e-08 35.4 0.0 8.2e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF4793 PF16041.5 KLO04419.1 - 0.14 12.3 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4793) DUF4873 PF16170.5 KLO04421.1 - 0.13 12.5 0.5 0.23 11.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4873) F-box-like PF12937.7 KLO04422.1 - 3.4e-07 30.1 0.2 8e-07 28.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO04422.1 - 4.1e-07 29.7 0.7 4.1e-07 29.7 0.7 2.1 2 0 0 2 2 2 1 F-box domain RNA_pol_Rpb5_N PF03871.14 KLO04422.1 - 0.026 15.1 0.1 0.087 13.4 0.1 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain F-box_4 PF15966.5 KLO04422.1 - 0.056 13.3 0.1 0.43 10.5 0.1 2.4 2 0 0 2 2 2 0 F-box Pox_Rap94 PF03294.14 KLO04425.1 - 0.26 9.4 0.0 0.33 9.0 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 Skp1 PF01466.19 KLO04431.1 - 5.3e-15 55.3 0.1 8.3e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KLO04431.1 - 1.7e-13 50.6 0.0 3.4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 KLO04431.1 - 0.14 12.4 0.1 1.4 9.2 0.1 2.2 1 1 0 1 1 1 0 BTB/POZ domain F-box-like PF12937.7 KLO04432.1 - 0.075 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 F-box-like Helicase_C PF00271.31 KLO04434.1 - 2e-18 66.8 0.0 2.9e-17 63.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO04434.1 - 3.4e-15 56.3 0.0 5.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO04434.1 - 0.0011 18.9 0.0 0.003 17.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KLO04434.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain NAD_binding_9 PF13454.6 KLO04434.1 - 0.053 13.5 0.1 0.2 11.7 0.1 1.7 1 1 1 2 2 2 0 FAD-NAD(P)-binding Radical_SAM PF04055.21 KLO04434.1 - 0.081 13.3 0.0 4.6 7.6 0.0 2.9 3 0 0 3 3 3 0 Radical SAM superfamily ATP-synt_Z PF16594.5 KLO04434.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated GSH_synth_ATP PF03917.17 KLO04436.1 - 3.3e-107 358.5 0.0 3.7e-107 358.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KLO04436.1 - 1.4e-33 115.4 0.0 2.3e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Fe-S_biosyn PF01521.20 KLO04437.1 - 3.1e-12 46.7 0.0 4.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DDE_1 PF03184.19 KLO04438.1 - 1.1e-06 28.4 0.1 0.0026 17.5 0.0 3.0 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.6 KLO04438.1 - 0.1 12.3 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease Spt5-NGN PF03439.13 KLO04441.1 - 1.6e-07 31.1 0.0 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KLO04441.1 - 0.00014 21.7 24.5 0.017 15.1 0.8 5.4 6 0 0 6 6 6 3 KOW motif Spt5_N PF11942.8 KLO04441.1 - 0.0084 17.1 2.5 0.0084 17.1 2.5 2.4 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 KLO04441.1 - 0.019 15.2 0.0 0.88 9.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) Endostatin PF06482.11 KLO04441.1 - 0.26 10.7 0.4 0.45 9.9 0.4 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin VPS13_C PF16909.5 KLO04442.1 - 0.3 10.9 1.6 0.77 9.5 0.1 2.3 3 0 0 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal Ig_2 PF13895.6 KLO04444.1 - 0.14 12.5 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain YqzE PF14038.6 KLO04444.1 - 0.3 11.1 1.2 4.1 7.5 0.4 2.3 2 0 0 2 2 2 0 YqzE-like protein DUF2584 PF10763.9 KLO04446.1 - 0.11 12.7 0.3 0.22 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2584) Transposase_21 PF02992.14 KLO04449.1 - 3e-08 33.2 0.0 3.7e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 KLO04449.1 - 0.00016 21.0 0.0 0.00021 20.6 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase Cytochrome_CBB3 PF13442.6 KLO04449.1 - 0.059 13.7 0.0 0.1 12.9 0.0 1.5 1 1 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DUF4218 PF13960.6 KLO04450.1 - 1.3e-05 24.8 0.1 1.8e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) F-box-like PF12937.7 KLO04456.1 - 0.024 14.6 0.1 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 F-box-like Plavaka PF18759.1 KLO04459.1 - 1.6e-59 201.8 0.0 4.2e-48 164.2 0.0 2.2 1 1 1 2 2 2 2 Plavaka transposase zf-C2H2 PF00096.26 KLO04459.1 - 0.025 15.0 0.2 0.098 13.2 0.2 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type Adaptin_N PF01602.20 KLO04465.1 - 1.4e-09 37.1 0.1 1.7e-09 36.8 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region zf-MYND PF01753.18 KLO04476.1 - 2.1e-05 24.5 10.1 4.1e-05 23.6 10.1 1.5 1 0 0 1 1 1 1 MYND finger HydF_tetramer PF18133.1 KLO04476.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain zf-C6H2 PF15801.5 KLO04476.1 - 0.12 12.6 5.6 0.26 11.6 5.6 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding KbaA PF14089.6 KLO04478.1 - 0.046 13.6 1.1 0.048 13.5 1.1 1.0 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation DUF1689 PF07954.11 KLO04478.1 - 0.11 12.9 0.3 0.12 12.8 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) DUF3035 PF11233.8 KLO04480.1 - 0.085 13.1 3.7 0.15 12.3 3.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3035) Kisspeptin PF15152.6 KLO04480.1 - 4.5 8.1 5.8 3.4 8.5 0.9 2.2 1 1 1 2 2 2 0 Kisspeptin HTH_Tnp_ISL3 PF13542.6 KLO04481.1 - 0.048 13.1 0.5 0.73 9.3 0.0 3.1 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 RS4NT PF08071.12 KLO04483.1 - 8.1e-22 77.1 5.8 1.1e-21 76.6 5.8 1.2 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KLO04483.1 - 1.4e-05 24.7 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 S4 domain RVT_1 PF00078.27 KLO04484.1 - 1.2e-05 24.9 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KLO04485.1 - 5.7e-10 39.1 0.0 9.2e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KLO04486.1 - 4.8e-26 91.7 0.0 5.5e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 RNase H DUF883 PF05957.13 KLO04487.1 - 0.021 15.4 4.1 0.4 11.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) WXG100 PF06013.12 KLO04487.1 - 0.025 14.8 0.3 0.025 14.8 0.3 3.6 3 1 1 4 4 4 0 Proteins of 100 residues with WXG FAM184 PF15665.5 KLO04487.1 - 0.11 12.3 5.5 0.21 11.4 5.5 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Gp58 PF07902.11 KLO04487.1 - 0.11 10.8 1.7 0.16 10.3 1.7 1.1 1 0 0 1 1 1 0 gp58-like protein ApoLp-III PF07464.11 KLO04487.1 - 0.14 12.3 3.3 0.23 11.5 3.3 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Rootletin PF15035.6 KLO04487.1 - 0.38 10.8 10.5 0.022 14.8 5.0 1.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion eIF3_subunit PF08597.10 KLO04487.1 - 0.76 9.6 5.8 1.1 9.2 5.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit WD40 PF00400.32 KLO04488.1 - 9.6e-51 168.7 31.0 1.6e-07 31.9 0.4 8.4 8 0 0 8 8 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO04488.1 - 1.2e-23 83.1 0.1 0.0018 18.6 0.0 7.5 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO04488.1 - 2.8e-10 39.7 2.8 0.016 14.2 0.0 5.7 2 2 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KLO04488.1 - 2.3e-09 37.8 0.1 0.0064 16.9 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KLO04488.1 - 3.6e-09 36.8 2.1 0.0063 16.4 0.1 4.3 2 2 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 KLO04488.1 - 4.3e-09 36.7 0.0 0.0054 17.0 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA PF00004.29 KLO04488.1 - 4.5e-09 36.8 0.0 0.0056 17.1 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PD40 PF07676.12 KLO04488.1 - 1.1e-08 34.8 0.1 1.3 9.0 0.0 5.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat AAA_18 PF13238.6 KLO04488.1 - 5.2e-06 27.0 0.0 0.043 14.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KLO04488.1 - 1.1e-05 24.8 0.1 0.21 10.8 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin RNA_helicase PF00910.22 KLO04488.1 - 2.5e-05 24.6 0.0 0.84 10.0 0.0 3.6 3 0 0 3 3 3 2 RNA helicase NB-ARC PF00931.22 KLO04488.1 - 3.2e-05 23.2 0.0 0.0053 16.0 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 KLO04488.1 - 5.1e-05 23.2 0.0 0.22 11.4 0.0 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase DUF2075 PF09848.9 KLO04488.1 - 0.00013 21.3 0.0 0.31 10.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) WD40_like PF17005.5 KLO04488.1 - 0.00032 20.1 0.0 0.006 16.0 0.0 2.8 3 1 1 4 4 4 1 WD40-like domain AAA_25 PF13481.6 KLO04488.1 - 0.0004 20.0 0.2 0.9 9.1 0.1 3.7 3 1 0 3 3 2 1 AAA domain Ploopntkinase3 PF18751.1 KLO04488.1 - 0.00063 19.7 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 KLO04488.1 - 0.00095 19.4 0.0 1.3 9.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KLO04488.1 - 0.0031 17.5 0.0 2.6 7.9 0.0 3.6 3 0 0 3 3 3 1 Rad17 P-loop domain Nbas_N PF15492.6 KLO04488.1 - 0.0034 16.8 1.4 2.7 7.2 0.0 4.2 3 2 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal ATPase_2 PF01637.18 KLO04488.1 - 0.0039 17.1 0.0 0.85 9.5 0.0 3.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KLO04488.1 - 0.0042 16.8 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KLO04488.1 - 0.0067 16.4 0.0 1.4 8.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 KLO04488.1 - 0.0074 15.6 0.0 1.3 8.2 0.0 3.4 4 0 0 4 4 4 1 KAP family P-loop domain Parvo_NS1 PF01057.17 KLO04488.1 - 0.0074 15.4 0.0 0.23 10.5 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ResIII PF04851.15 KLO04488.1 - 0.0076 16.3 0.0 0.23 11.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KLO04488.1 - 0.0088 16.3 0.0 7.8 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KLO04488.1 - 0.013 16.0 0.4 3.7 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KLO04488.1 - 0.016 15.0 0.1 0.93 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KLO04488.1 - 0.023 15.2 0.0 2.6 8.6 0.0 2.9 3 0 0 3 3 2 0 ABC transporter Mg_chelatase PF01078.21 KLO04488.1 - 0.026 13.9 0.0 5.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.11 KLO04488.1 - 0.028 13.4 0.0 0.1 11.5 0.0 1.8 2 0 0 2 2 2 0 PrkA AAA domain SesA PF17107.5 KLO04488.1 - 0.036 14.2 0.1 5.3 7.3 0.0 3.2 3 0 0 3 3 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases IstB_IS21 PF01695.17 KLO04488.1 - 0.037 13.8 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KLO04488.1 - 0.04 14.1 0.0 7.5 6.7 0.0 3.1 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 KLO04488.1 - 0.062 13.6 0.1 4.8 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF3634 PF12321.8 KLO04488.1 - 0.073 13.5 0.1 0.23 11.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3634) AAA_14 PF13173.6 KLO04488.1 - 0.1 12.6 0.0 17 5.5 0.0 3.5 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 KLO04488.1 - 0.1 11.6 0.0 1.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Torsin PF06309.11 KLO04488.1 - 0.11 12.6 0.0 22 5.2 0.0 2.5 2 0 0 2 2 2 0 Torsin Gmad1 PF10647.9 KLO04488.1 - 0.2 11.4 0.3 8.1 6.1 0.0 3.1 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Mod_r PF07200.13 KLO04488.1 - 0.28 11.3 0.9 0.72 9.9 0.1 2.1 2 0 0 2 2 1 0 Modifier of rudimentary (Mod(r)) protein Cyclin PF08613.11 KLO04490.1 - 8.9e-05 22.9 0.8 0.0028 18.1 0.0 2.5 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KLO04490.1 - 0.0096 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain PriC PF07445.12 KLO04490.1 - 0.13 12.2 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Primosomal replication protein priC DUF5355 PF17306.2 KLO04492.1 - 0.17 10.9 0.0 0.19 10.7 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5355) zf-MYND PF01753.18 KLO04494.1 - 2.4e-06 27.5 9.4 6.1e-06 26.2 9.4 1.7 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 KLO04494.1 - 0.16 9.8 2.2 0.23 9.3 2.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-Mss51 PF13824.6 KLO04494.1 - 0.24 11.5 1.7 0.58 10.3 1.7 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Mucin15 PF15672.5 KLO04502.1 - 0.075 12.5 0.1 0.075 12.5 0.1 2.0 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 PepSY_TM PF03929.16 KLO04502.1 - 0.093 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 PepSY-associated TM region F-box-like PF12937.7 KLO04506.1 - 2.4e-05 24.1 2.8 2.4e-05 24.1 2.8 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO04506.1 - 0.00031 20.5 1.9 0.0029 17.4 1.9 2.6 1 1 0 1 1 1 1 F-box domain RVP_2 PF08284.11 KLO04509.1 - 5.2e-05 23.0 0.0 6.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KLO04509.1 - 0.00017 22.1 0.0 0.00019 22.0 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KLO04509.1 - 0.00069 20.1 0.0 0.00082 19.9 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Cauli_VI PF01693.16 KLO04513.1 - 2.2e-09 37.5 0.5 3.4e-09 36.9 0.5 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Oxidored-like PF09791.9 KLO04513.1 - 0.01 15.5 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal CxC2 PF18803.1 KLO04514.1 - 6.4e-33 113.1 0.0 1e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO04514.1 - 1.4e-06 28.3 2.0 1.8e-06 28.0 0.0 2.1 1 1 1 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KLO04514.1 - 0.00012 21.9 0.0 0.00012 21.9 0.0 1.9 2 1 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases Sars6 PF12133.8 KLO04517.1 - 0.12 12.3 0.6 0.23 11.4 0.6 1.5 1 1 0 1 1 1 0 Open reading frame 6 from SARS coronavirus TpcC PF12642.7 KLO04518.1 - 0.05 13.4 0.7 2.1 8.1 0.1 2.2 2 0 0 2 2 2 0 Conjugative transposon protein TcpC ThiW PF09512.10 KLO04521.1 - 0.094 12.8 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) FAM178 PF14816.6 KLO04522.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 CNP1 PF08750.11 KLO04523.1 - 0.032 14.2 0.2 0.043 13.8 0.2 1.2 1 0 0 1 1 1 0 CNP1-like family DAO PF01266.24 KLO04525.1 - 2.1e-06 27.5 0.6 3.3e-06 26.9 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KLO04525.1 - 8.4e-05 22.1 1.7 0.00012 21.6 1.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO04525.1 - 0.00023 20.4 0.3 0.00029 20.1 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO04525.1 - 0.00043 19.6 0.0 0.00046 19.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO04525.1 - 0.0025 18.3 0.1 0.0038 17.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO04525.1 - 0.0043 15.8 0.3 0.0058 15.4 0.3 1.1 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KLO04525.1 - 0.0059 16.8 0.1 0.01 16.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KLO04525.1 - 0.013 15.4 0.1 0.018 14.9 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KLO04525.1 - 0.015 14.4 0.3 0.02 14.0 0.3 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KLO04525.1 - 0.069 12.4 0.1 0.098 11.9 0.1 1.1 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KLO04525.1 - 0.07 12.4 0.3 0.1 11.8 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KLO04525.1 - 0.22 10.7 0.2 0.3 10.3 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KLO04525.1 - 0.25 10.3 0.6 0.35 9.8 0.6 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein RYDR_ITPR PF01365.21 KLO04527.1 - 0.0032 16.9 0.9 0.019 14.4 0.2 2.0 1 1 1 2 2 2 1 RIH domain Phasin PF05597.11 KLO04527.1 - 0.03 14.3 0.3 0.052 13.5 0.3 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Erf4 PF10256.9 KLO04530.1 - 0.0056 16.8 0.0 0.0067 16.5 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF1554 PF07588.11 KLO04535.1 - 0.18 11.6 0.0 0.26 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1554) DUF4196 PF13846.6 KLO04535.1 - 9.3 6.5 11.0 1 9.6 1.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4196) Levi_coat PF01819.17 KLO04539.1 - 0.01 15.9 0.4 0.013 15.5 0.4 1.1 1 0 0 1 1 1 0 Levivirus coat protein Dsh_C PF12316.8 KLO04539.1 - 0.07 13.5 0.1 0.088 13.2 0.1 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal WD40 PF00400.32 KLO04544.1 - 8.5e-20 70.7 8.6 2.8e-08 34.3 0.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO04544.1 - 9.7e-08 32.2 0.0 0.027 14.7 0.0 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO04544.1 - 0.00078 18.5 0.0 0.05 12.6 0.0 2.1 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SGL PF08450.12 KLO04544.1 - 0.019 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Nucleoporin_N PF08801.11 KLO04544.1 - 0.022 13.5 0.1 0.029 13.1 0.1 1.1 1 0 0 1 1 1 0 Nup133 N terminal like Nbas_N PF15492.6 KLO04544.1 - 0.023 14.0 0.3 2.6 7.3 0.0 2.2 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RVP PF00077.20 KLO04548.1 - 0.073 13.4 0.0 0.18 12.1 0.0 1.6 1 1 1 2 2 2 0 Retroviral aspartyl protease UBA_4 PF14555.6 KLO04548.1 - 0.15 11.9 0.0 0.87 9.5 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain WD40 PF00400.32 KLO04551.1 - 1.2e-09 38.6 0.9 2.5e-05 24.9 0.5 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO04551.1 - 0.017 15.4 0.1 0.63 10.4 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF808 PF05661.12 KLO04551.1 - 0.05 12.6 0.1 0.077 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) HTH_Tnp_Tc5 PF03221.16 KLO04553.1 - 1e-07 31.9 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KLO04554.1 - 5.2e-26 91.4 0.0 7.2e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO04554.1 - 6.9e-06 25.9 0.0 0.057 13.2 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease DUF3545 PF12065.8 KLO04555.1 - 0.028 14.4 0.8 0.062 13.3 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) BTB PF00651.31 KLO04558.1 - 9.8e-05 22.6 0.0 0.00026 21.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF4329 PF14220.6 KLO04559.1 - 2.4e-07 30.8 0.0 3.1e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4329) Prok-JAB PF14464.6 KLO04559.1 - 0.0012 18.6 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4329 PF14220.6 KLO04560.1 - 1.7e-05 24.8 0.0 2.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4329) Prok-JAB PF14464.6 KLO04560.1 - 0.0054 16.5 0.0 0.0067 16.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Miff PF05644.11 KLO04560.1 - 0.22 11.1 0.0 0.28 10.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF4329 PF14220.6 KLO04561.1 - 1e-05 25.5 0.0 1.5e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4329) Prok-JAB PF14464.6 KLO04561.1 - 0.0018 18.1 0.1 0.0025 17.6 0.1 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Polysacc_lyase PF14099.6 KLO04561.1 - 0.015 15.1 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase eIF3m_C_helix PF18005.1 KLO04562.1 - 0.066 12.9 0.5 0.57 9.9 0.1 2.1 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix Pkinase PF00069.25 KLO04563.1 - 7.6e-29 100.9 0.0 9.5e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO04563.1 - 2.4e-28 99.1 0.0 3.3e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CENP-U PF13097.6 KLO04565.1 - 6.6e-05 22.9 0.2 8e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 CENP-A nucleosome associated complex (NAC) subunit p450 PF00067.22 KLO04572.1 - 5e-53 180.5 0.0 1.1e-52 179.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DLEU7 PF15760.5 KLO04572.1 - 0.032 13.7 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Leukemia-associated protein 7 Asr PF06392.11 KLO04573.1 - 0.15 12.5 2.2 0.15 12.5 2.2 2.1 2 0 0 2 2 2 0 Acid shock protein repeat APH PF01636.23 KLO04574.1 - 4.2e-09 36.7 0.0 6.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Dpy-30 PF05186.13 KLO04577.1 - 0.021 14.5 0.2 0.046 13.4 0.0 1.6 2 0 0 2 2 2 0 Dpy-30 motif CENP-U PF13097.6 KLO04579.1 - 0.00027 21.0 0.1 0.00033 20.6 0.1 1.2 1 0 0 1 1 1 1 CENP-A nucleosome associated complex (NAC) subunit Pkinase PF00069.25 KLO04581.1 - 1.6e-27 96.5 0.0 1.8e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO04581.1 - 2.7e-26 92.4 0.0 2.9e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO04581.1 - 0.021 14.8 0.0 0.037 13.9 0.0 1.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family RVT_1 PF00078.27 KLO04582.1 - 2.4e-06 27.2 0.0 6.5e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.6 KLO04586.1 - 4.9e-08 32.9 0.0 5.6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO04587.1 - 8.3e-10 38.6 0.0 8.9e-10 38.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 KLO04588.1 - 7.2e-11 41.6 0.4 1e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KLO04588.1 - 4.9e-09 36.7 1.5 7.6e-09 36.1 1.5 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 KLO04588.1 - 2e-07 30.5 0.3 1.7e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_29 PF13551.6 KLO04588.1 - 2.8e-07 30.4 0.4 2.6e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KLO04588.1 - 3.2e-06 27.3 0.2 1.9e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Transposase HTH_IclR PF09339.10 KLO04588.1 - 0.0004 20.1 0.0 0.0011 18.7 0.0 1.8 2 0 0 2 2 1 1 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.12 KLO04588.1 - 0.00048 19.7 0.1 0.016 14.9 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 KLO04588.1 - 0.0012 18.8 0.3 0.0023 17.9 0.0 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 KLO04588.1 - 0.0023 17.8 0.0 0.44 10.5 0.0 2.3 2 0 0 2 2 2 1 HTH domain HTH_Tnp_ISL3 PF13542.6 KLO04588.1 - 0.0031 16.9 2.1 0.47 9.9 0.1 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_IS630 PF01710.16 KLO04588.1 - 0.0043 17.1 0.1 0.11 12.6 0.0 2.1 1 1 1 2 2 2 1 Transposase TrmB PF01978.19 KLO04588.1 - 0.0065 16.3 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 KLO04588.1 - 0.012 15.9 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 KLO04588.1 - 0.015 15.2 0.3 0.081 12.8 0.0 2.1 2 0 0 2 2 2 0 MarR family DUF134 PF02001.16 KLO04588.1 - 0.036 14.6 0.2 3.3 8.3 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF134 HTH_7 PF02796.15 KLO04588.1 - 0.049 13.7 0.2 0.88 9.7 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KLO04588.1 - 0.054 13.6 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KLO04588.1 - 0.095 12.2 0.0 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_21 PF13276.6 KLO04588.1 - 0.12 12.5 0.5 0.36 11.0 0.3 1.9 2 1 0 2 2 2 0 HTH-like domain HTH_43 PF09904.9 KLO04588.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_4 PF13613.6 KLO04588.1 - 0.16 11.7 0.3 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HBB PF06777.11 KLO04589.1 - 0.086 12.5 0.6 0.24 11.0 0.3 1.9 2 0 0 2 2 2 0 Helical and beta-bridge domain Syntaxin_2 PF14523.6 KLO04589.1 - 2.2 8.7 6.1 2.4 8.6 0.1 3.2 3 1 0 3 3 3 0 Syntaxin-like protein WD40 PF00400.32 KLO04592.1 - 1.7e-09 38.2 0.5 7.6e-05 23.4 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO04592.1 - 0.0004 20.6 0.0 0.033 14.5 0.0 2.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KLO04592.1 - 0.0086 15.4 0.0 1.1 8.4 0.0 2.1 1 1 1 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus RIBIOP_C PF04950.12 KLO04593.1 - 1.3e-95 320.2 0.0 1.3e-95 320.2 0.0 2.7 3 0 0 3 3 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KLO04593.1 - 3e-27 94.5 0.0 9.1e-27 93.0 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 KLO04593.1 - 3e-05 24.5 0.3 0.00014 22.3 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 KLO04593.1 - 0.00012 22.2 2.1 0.00015 21.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 KLO04593.1 - 0.00013 22.3 0.0 0.00036 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KLO04593.1 - 0.0002 21.3 0.2 0.0014 18.5 0.1 2.3 3 0 0 3 3 2 1 RsgA GTPase ABC_tran PF00005.27 KLO04593.1 - 0.00028 21.4 1.5 0.00053 20.5 0.0 2.2 2 0 0 2 2 1 1 ABC transporter GTP_EFTU PF00009.27 KLO04593.1 - 0.00037 20.1 2.0 0.062 12.8 0.0 3.2 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KLO04593.1 - 0.0027 17.8 0.2 0.0096 16.0 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KLO04593.1 - 0.0036 17.7 0.0 0.01 16.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA PF00004.29 KLO04593.1 - 0.0043 17.5 0.0 0.012 16.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rtf2 PF04641.12 KLO04593.1 - 0.0051 16.2 3.5 0.0051 16.2 3.5 2.6 3 0 0 3 3 2 1 Rtf2 RING-finger PduV-EutP PF10662.9 KLO04593.1 - 0.0063 16.3 0.1 0.016 14.9 0.1 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KLO04593.1 - 0.01 16.4 0.9 0.089 13.3 0.1 3.1 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KLO04593.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 KLO04593.1 - 0.038 13.3 0.0 0.084 12.1 0.0 1.5 1 0 0 1 1 1 0 Septin NB-ARC PF00931.22 KLO04593.1 - 0.038 13.2 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 KLO04593.1 - 0.046 13.8 0.1 0.39 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KLO04593.1 - 0.06 13.6 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KLO04593.1 - 0.064 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KLO04593.1 - 0.072 12.8 0.1 0.23 11.2 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KLO04593.1 - 0.075 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KLO04593.1 - 0.089 12.9 0.1 0.089 12.9 0.1 2.3 3 0 0 3 3 2 0 Helicase HerA, central domain MobB PF03205.14 KLO04593.1 - 0.11 12.4 0.5 1.8 8.5 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 KLO04593.1 - 0.13 11.7 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KLO04593.1 - 6.7 7.2 10.4 16 5.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain Cep57_MT_bd PF06657.13 KLO04594.1 - 2.4e-23 82.3 0.0 2.4e-23 82.3 0.0 3.9 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KLO04594.1 - 6.7e-08 32.5 7.8 6.7e-08 32.5 7.8 2.9 2 1 0 2 2 2 1 Centrosome localisation domain of PPC89 IZUMO PF15005.6 KLO04594.1 - 0.12 12.9 5.7 0.074 13.6 2.6 2.1 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF4279 PF14106.6 KLO04594.1 - 0.13 12.5 1.6 21 5.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4279) ZapB PF06005.12 KLO04594.1 - 4 8.0 25.7 7.7 7.0 10.3 4.4 3 1 1 4 4 4 0 Cell division protein ZapB APOBEC4 PF18775.1 KLO04600.1 - 0.028 14.6 0.1 0.084 13.0 0.1 1.8 1 1 0 1 1 1 0 APOBEC4 Abhydrolase_8 PF06259.12 KLO04602.1 - 0.04 13.5 0.1 0.049 13.3 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase TMEM40 PF15817.5 KLO04603.1 - 1.2 8.9 9.4 2.3 8.0 1.8 3.0 1 1 1 2 2 2 0 Transmembrane protein 40 family Lactonase PF10282.9 KLO04604.1 - 7.3e-45 153.7 0.0 9.1e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Csm1_N PF18504.1 KLO04608.1 - 0.0082 16.5 8.6 0.014 15.7 3.2 2.3 1 1 1 2 2 2 1 Csm1 N-terminal domain BLOC1_2 PF10046.9 KLO04608.1 - 0.036 14.4 1.7 0.073 13.4 0.2 2.1 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.8 KLO04608.1 - 2.5 8.1 8.0 5.8 7.0 1.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 KLO04608.1 - 2.7 8.1 7.2 8.6 6.4 1.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Med9 PF07544.13 KLO04608.1 - 5.1 7.3 8.1 2.2 8.5 0.7 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 WD40 PF00400.32 KLO04610.1 - 5e-11 43.0 5.5 2.9e-05 24.7 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO04610.1 - 1.8e-05 24.9 0.0 0.0077 16.5 0.0 3.0 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KLO04610.1 - 4.9e-05 22.8 0.1 0.0028 17.0 0.0 2.5 2 1 1 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus PALB2_WD40 PF16756.5 KLO04610.1 - 0.11 11.4 0.2 0.25 10.2 0.1 1.5 1 1 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain HTH_Tnp_Tc5 PF03221.16 KLO04611.1 - 6.1e-12 45.4 0.1 1.3e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain MarR PF01047.22 KLO04611.1 - 0.0067 16.3 0.0 0.032 14.2 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_Tnp_4 PF13613.6 KLO04611.1 - 0.012 15.4 0.0 0.086 12.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_3 PF01381.22 KLO04611.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix CENP-B_N PF04218.13 KLO04611.1 - 0.063 12.9 0.1 0.52 10.0 0.1 2.2 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain ArenaCapSnatch PF17296.2 KLO04611.1 - 0.13 11.7 0.1 13 5.2 0.0 2.4 1 1 0 2 2 2 0 Arenavirus cap snatching domain MaoC_dehydrat_N PF13452.6 KLO04613.1 - 0.039 14.1 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase F-box-like PF12937.7 KLO04614.1 - 6.7e-07 29.1 0.8 2.1e-06 27.5 0.0 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO04614.1 - 0.00032 20.5 0.6 0.0048 16.8 0.1 2.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KLO04615.1 - 1.8e-05 24.5 3.2 9.3e-05 22.2 0.0 3.3 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 KLO04615.1 - 4.4 7.3 8.7 0.56 10.2 1.6 3.2 3 1 0 3 3 3 0 F-box domain CALCOCO1 PF07888.11 KLO04616.1 - 0.00019 20.4 3.8 0.00021 20.3 3.8 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_TATA_bd PF12325.8 KLO04616.1 - 0.0089 16.2 1.9 1.6 9.0 0.5 2.2 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 KLO04616.1 - 0.1 12.7 1.3 0.46 10.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1818 PF08848.11 KLO04616.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) SlyX PF04102.12 KLO04616.1 - 0.16 12.6 2.5 0.58 10.8 0.3 2.2 2 0 0 2 2 2 0 SlyX Cnn_1N PF07989.11 KLO04616.1 - 0.2 11.8 1.8 10 6.4 0.2 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF724 PF05266.14 KLO04616.1 - 0.23 11.3 1.5 0.37 10.6 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) BST2 PF16716.5 KLO04616.1 - 0.3 11.7 3.1 16 6.2 0.2 2.5 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 HIP1_clath_bdg PF16515.5 KLO04616.1 - 0.45 11.2 5.8 2.7 8.7 0.9 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pox_A_type_inc PF04508.12 KLO04616.1 - 1.6 8.7 5.0 12 5.9 0.1 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat BTB PF00651.31 KLO04617.1 - 0.0029 17.8 0.0 0.0047 17.1 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Erf4 PF10256.9 KLO04618.1 - 0.051 13.7 0.0 0.087 12.9 0.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family BTB PF00651.31 KLO04619.1 - 0.012 15.9 0.0 0.035 14.3 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain SinI PF08671.10 KLO04619.1 - 0.075 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Anti-repressor SinI GRP PF07172.11 KLO04628.1 - 7.3 7.4 34.1 13 6.5 34.1 1.3 1 0 0 1 1 1 0 Glycine rich protein family KDZ PF18758.1 KLO04629.1 - 1.7e-85 286.2 0.0 4.3e-85 284.9 0.0 1.7 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KLO04629.1 - 0.017 15.3 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases InvH PF04741.12 KLO04630.1 - 0.054 13.4 0.2 0.17 11.8 0.2 1.8 1 0 0 1 1 1 0 InvH outer membrane lipoprotein MCPVI PF02993.14 KLO04630.1 - 1.5 8.6 13.0 0.027 14.3 4.0 2.3 2 0 0 2 2 2 0 Minor capsid protein VI Spt5-NGN PF03439.13 KLO04631.1 - 6.4e-11 42.0 0.1 2.9e-10 39.9 0.1 2.1 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KLO04631.1 - 0.00011 22.0 19.2 0.01 15.8 0.9 3.6 3 0 0 3 3 3 3 KOW motif DUF3912 PF13051.6 KLO04631.1 - 0.15 12.4 2.7 16 5.8 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3912) Phytochelatin_C PF09328.10 KLO04631.1 - 0.27 10.5 1.3 0.49 9.7 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) Spt5_N PF11942.8 KLO04631.1 - 0.31 12.0 13.1 0.7 10.9 13.1 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal ATP-synt_E PF05680.12 KLO04632.1 - 0.037 14.4 0.2 0.037 14.4 0.2 2.0 2 0 0 2 2 2 0 ATP synthase E chain HTH_32 PF13565.6 KLO04633.1 - 0.00017 22.1 0.0 0.00019 22.0 0.0 1.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KLO04633.1 - 0.0057 16.6 0.1 0.0065 16.5 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn helix DDE_3 PF13358.6 KLO04634.1 - 2e-09 37.4 0.0 2.2e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO04635.1 - 1.2e-08 34.8 0.0 2.5e-08 33.8 0.0 1.5 1 1 1 2 2 2 1 DDE superfamily endonuclease Nif11 PF07862.11 KLO04637.1 - 0.081 13.2 1.3 0.19 12.1 0.5 2.0 2 0 0 2 2 2 0 Nif11 domain Mito_fiss_reg PF05308.11 KLO04637.1 - 2 8.5 11.5 4.2 7.4 11.5 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator TolA_bind_tri PF16331.5 KLO04641.1 - 0.00062 19.8 0.1 0.0016 18.5 0.0 1.7 1 1 0 1 1 1 1 TolA binding protein trimerisation LPP PF04728.13 KLO04641.1 - 0.019 15.3 0.1 0.27 11.6 0.0 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Apolipoprotein PF01442.18 KLO04641.1 - 0.02 14.8 0.2 0.03 14.2 0.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CCCAP PF15964.5 KLO04641.1 - 0.025 12.9 0.1 0.033 12.5 0.1 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family PRIMA1 PF16101.5 KLO04641.1 - 0.028 14.5 6.8 0.042 13.9 5.9 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Baculo_PEP_C PF04513.12 KLO04641.1 - 0.037 14.1 7.7 0.1 12.6 7.5 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HsbA PF12296.8 KLO04641.1 - 0.047 14.1 4.4 0.23 11.9 0.6 2.4 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Laminin_II PF06009.12 KLO04641.1 - 0.048 13.7 0.3 0.13 12.3 0.2 1.8 1 1 0 1 1 1 0 Laminin Domain II DUF1664 PF07889.12 KLO04641.1 - 0.056 13.5 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KLO04641.1 - 0.073 13.5 2.6 1.4 9.4 2.6 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 KLO04641.1 - 0.074 13.1 0.1 5.7 7.0 0.0 2.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.7 KLO04641.1 - 0.13 11.8 0.2 0.27 10.8 0.2 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Fib_alpha PF08702.10 KLO04641.1 - 0.14 12.4 0.8 0.21 11.8 0.4 1.5 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family CAP_N PF01213.19 KLO04641.1 - 4.2 6.8 9.0 2.2 7.7 7.0 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal KDZ PF18758.1 KLO04642.1 - 2.2e-50 171.3 0.1 1.4e-49 168.8 0.0 2.1 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO04642.1 - 2.8e-36 123.9 0.3 5.3e-36 123.0 0.3 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO04642.1 - 1.3e-08 34.9 1.0 2.5e-08 34.0 0.3 1.8 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KLO04642.1 - 0.00013 21.8 0.1 0.00037 20.3 0.1 1.7 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases zf-H3C2 PF16721.5 KLO04642.1 - 0.039 14.3 0.1 0.088 13.2 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding Cauli_VI PF01693.16 KLO04643.1 - 0.019 15.3 0.1 0.034 14.4 0.1 1.4 1 0 0 1 1 1 0 Caulimovirus viroplasmin Semialdhyde_dhC PF02774.18 KLO04644.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain MCM_bind PF09739.9 KLO04644.1 - 0.29 9.5 1.6 0.43 9.0 1.6 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor HNF-1_N PF04814.13 KLO04644.1 - 1 9.9 9.4 2.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Plavaka PF18759.1 KLO04652.1 - 4.5e-123 410.6 0.0 6.1e-123 410.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase NPV_P10 PF05531.12 KLO04653.1 - 0.0051 17.2 2.1 0.011 16.1 2.1 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KLO04653.1 - 0.0092 16.0 4.1 0.026 14.6 4.1 1.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.11 KLO04653.1 - 0.0094 15.8 7.4 0.0094 15.8 7.4 2.0 2 0 0 2 2 2 1 Phage minor structural protein GP20 JIP_LZII PF16471.5 KLO04653.1 - 0.014 15.6 1.6 0.036 14.2 1.6 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II HSBP1 PF06825.12 KLO04653.1 - 0.11 12.4 0.2 19 5.2 0.0 2.7 1 1 2 3 3 3 0 Heat shock factor binding protein 1 DUF16 PF01519.16 KLO04653.1 - 0.2 12.2 3.7 0.18 12.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 LPP PF04728.13 KLO04653.1 - 0.57 10.6 3.6 35 4.9 3.5 3.2 1 1 0 1 1 1 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 KLO04653.1 - 2.8 8.0 5.3 0.49 10.4 1.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.17 KLO04654.1 - 0.0014 18.8 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein KDZ PF18758.1 KLO04655.1 - 9e-42 143.2 0.0 1e-41 143.0 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO04656.1 - 8.1e-25 87.1 0.2 1.5e-24 86.3 0.2 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO04656.1 - 0.044 13.9 0.1 0.044 13.9 0.1 1.6 2 0 0 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases DUF2797 PF10977.8 KLO04656.1 - 0.38 10.6 1.8 0.58 10.0 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) ATP-synt_E PF05680.12 KLO04657.1 - 0.016 15.5 0.1 0.027 14.8 0.1 1.3 1 0 0 1 1 1 0 ATP synthase E chain Spt5-NGN PF03439.13 KLO04659.1 - 1.6e-07 31.1 0.0 3.8e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF2213 PF09979.9 KLO04659.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) KOW PF00467.29 KLO04659.1 - 3 7.9 25.5 1.8 8.6 1.7 4.4 4 0 0 4 4 4 0 KOW motif Membr_traf_MHD PF10540.9 KLO04660.1 - 0.093 12.9 0.3 0.15 12.2 0.3 1.3 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain FAM76 PF16046.5 KLO04661.1 - 0.031 13.6 0.7 0.05 12.9 0.7 1.3 1 0 0 1 1 1 0 FAM76 protein ECR1_N PF14382.6 KLO04663.1 - 1.6 8.6 5.8 0.54 10.1 0.7 2.6 3 0 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region WPP PF13943.6 KLO04665.1 - 0.1 13.0 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 WPP domain Polysacc_deac_1 PF01522.21 KLO04667.1 - 3.4e-08 33.4 0.0 5.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase HTH_23 PF13384.6 KLO04667.1 - 0.094 12.5 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain DUF2316 PF10078.9 KLO04667.1 - 0.18 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF1180 PF06679.12 KLO04667.1 - 0.28 11.6 1.5 0.41 11.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) F-box PF00646.33 KLO04669.1 - 0.00036 20.3 1.9 0.0028 17.5 0.1 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KLO04669.1 - 0.00063 19.6 0.8 0.009 15.9 0.0 2.7 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KLO04669.1 - 0.027 14.3 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 F-box Hist_deacetyl PF00850.19 KLO04670.1 - 5.9e-53 180.3 0.0 7.2e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain NatB_MDM20 PF09797.9 KLO04672.1 - 2e-75 254.1 0.1 3.3e-75 253.4 0.1 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 KLO04672.1 - 0.0019 18.9 0.3 0.28 12.1 0.1 3.9 2 1 2 4 4 4 1 Tetratricopeptide repeat BTB PF00651.31 KLO04673.1 - 6.2e-05 23.2 0.0 0.0002 21.5 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain Zn_Tnp_IS1595 PF12760.7 KLO04673.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF5334 PF17268.2 KLO04674.1 - 0.028 14.7 0.1 0.14 12.5 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5334) RPA_C PF08784.11 KLO04674.1 - 0.037 14.7 1.0 0.21 12.3 0.0 2.2 2 0 0 2 2 2 0 Replication protein A C terminal T5orf172 PF10544.9 KLO04674.1 - 0.22 12.1 1.1 5.5 7.6 1.1 2.3 1 1 0 1 1 1 0 T5orf172 domain AUDH_Cupin PF18637.1 KLO04679.1 - 7.3e-63 211.3 0.7 1.2e-62 210.5 0.7 1.4 1 0 0 1 1 1 1 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain PBP3 PF18056.1 KLO04679.1 - 1.7e-27 95.7 0.0 3.4e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Penicillin Binding Protein 3 Domain RicinB_lectin_2 PF14200.6 KLO04679.1 - 0.00039 21.1 0.0 0.0023 18.6 0.0 2.2 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like VCBS PF13517.6 KLO04679.1 - 0.026 15.1 8.4 0.64 10.6 0.8 4.1 4 1 1 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KLO04679.1 - 0.14 12.3 0.6 0.55 10.4 0.6 2.1 1 0 0 1 1 1 0 FG-GAP repeat F420_oxidored PF03807.17 KLO04680.1 - 0.00019 21.9 0.1 0.00029 21.3 0.1 1.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KLO04680.1 - 0.0032 17.4 0.0 0.0038 17.1 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KLO04680.1 - 0.0095 15.9 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.14 KLO04680.1 - 0.052 12.8 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KLO04680.1 - 0.063 12.5 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 KLO04680.1 - 0.064 13.7 0.0 0.082 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding Epimerase PF01370.21 KLO04680.1 - 0.065 12.7 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO04680.1 - 0.069 12.5 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KLO04680.1 - 0.072 13.3 0.0 0.093 13.0 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.6 KLO04680.1 - 0.078 13.2 0.0 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.15 KLO04680.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 KLO04680.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase ADH_zinc_N PF00107.26 KLO04681.1 - 3.6e-17 62.6 0.0 5.8e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO04681.1 - 7.7e-10 39.9 0.0 2.2e-09 38.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO04681.1 - 3e-08 33.5 0.0 7.1e-08 32.3 0.0 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KLO04681.1 - 0.001 18.9 0.1 0.0066 16.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase THF_DHG_CYH_C PF02882.19 KLO04681.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NDUF_B7 PF05676.13 KLO04682.1 - 0.023 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) F-box-like PF12937.7 KLO04683.1 - 2.6e-12 46.4 2.5 6.6e-12 45.1 0.5 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO04683.1 - 0.017 15.0 1.3 0.081 12.8 1.3 2.2 1 1 0 1 1 1 0 F-box domain F-box-like_2 PF13013.6 KLO04683.1 - 0.097 12.6 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain Peptidase_C48 PF02902.19 KLO04687.1 - 1e-13 51.6 1.7 1.6e-13 51.0 1.7 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain ADIP PF11559.8 KLO04688.1 - 0.022 14.9 0.3 0.047 13.8 0.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding AT_hook PF02178.19 KLO04689.1 - 6.4 7.0 13.1 0.11 12.5 4.4 2.8 2 0 0 2 2 2 0 AT hook motif DDE_3 PF13358.6 KLO04690.1 - 1.2e-08 34.8 0.2 1.5e-08 34.5 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO04691.1 - 1.7e-08 34.3 0.0 1.8e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 KLO04692.1 - 3.7e-08 32.9 0.3 3.2e-07 29.9 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 KLO04692.1 - 9.3e-08 32.6 0.5 1.2e-07 32.2 0.5 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 KLO04692.1 - 3.4e-05 23.5 1.2 0.0032 17.2 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KLO04692.1 - 6.5e-05 23.1 0.1 0.00017 21.8 0.1 1.7 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.6 KLO04692.1 - 0.0093 16.0 0.4 0.038 14.0 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_7 PF02796.15 KLO04692.1 - 0.042 13.9 0.7 1.1 9.4 0.1 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase TrmB PF01978.19 KLO04692.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Pkinase_Tyr PF07714.17 KLO04698.1 - 3.1e-33 115.2 0.0 4.3e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO04698.1 - 8.1e-28 97.5 0.0 1.2e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO04699.1 - 1.3e-31 109.9 0.0 1.6e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO04699.1 - 6.2e-29 101.2 0.0 7.3e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO04699.1 - 0.00023 20.6 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO04699.1 - 0.00069 19.0 0.0 0.00082 18.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO04699.1 - 0.0073 15.9 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KLO04704.1 - 2.7e-32 112.2 0.0 3.2e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO04704.1 - 4.6e-28 98.2 0.0 7.9e-28 97.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO04704.1 - 0.0042 16.5 0.0 0.0074 15.6 0.0 1.3 1 1 0 1 1 1 1 Kinase-like DTHCT PF08070.11 KLO04708.1 - 4.3 8.1 17.6 9.5 7.0 17.0 1.7 1 1 1 2 2 2 0 DTHCT (NUC029) region F-box-like PF12937.7 KLO04710.1 - 0.00022 21.0 2.0 0.16 11.9 0.1 2.9 2 1 0 2 2 2 2 F-box-like F-box PF00646.33 KLO04710.1 - 0.0054 16.6 8.3 0.25 11.3 0.6 4.0 4 1 0 4 4 4 2 F-box domain F-box-like PF12937.7 KLO04711.1 - 0.0066 16.3 0.1 0.0099 15.8 0.1 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO04711.1 - 0.02 14.8 0.4 0.1 12.5 0.4 2.0 1 1 0 1 1 1 0 F-box domain Cyclin PF08613.11 KLO04713.1 - 0.00012 22.4 0.0 0.0049 17.2 0.0 2.4 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KLO04713.1 - 0.052 13.3 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Dmrt1 PF12374.8 KLO04713.1 - 0.24 11.9 0.1 0.24 11.9 0.1 4.0 4 1 1 5 5 5 0 Double-sex mab3 related transcription factor 1 Transposase_21 PF02992.14 KLO04714.1 - 6.9e-06 25.5 0.0 0.00014 21.2 0.0 2.3 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 KLO04714.1 - 0.015 14.9 0.1 0.048 13.3 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4218) FAM104 PF15434.6 KLO04715.1 - 0.1 13.2 6.5 0.15 12.6 1.4 2.6 2 0 0 2 2 2 0 Family 104 Pap_E4 PF02711.14 KLO04715.1 - 0.14 13.1 0.5 0.14 13.1 0.5 2.1 2 0 0 2 2 2 0 E4 protein DUF1664 PF07889.12 KLO04715.1 - 1.3 9.0 6.3 0.66 10.0 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Pox_F11 PF04943.12 KLO04715.1 - 3.1 6.8 5.9 5.2 6.0 5.9 1.3 1 0 0 1 1 1 0 Poxvirus F11 protein Atg14 PF10186.9 KLO04715.1 - 3.3 6.7 10.5 29 3.6 8.8 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KLO04715.1 - 4.3 6.1 14.7 0.56 9.0 10.0 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.13 KLO04715.1 - 6.8 5.8 6.0 11 5.1 6.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein AAA_13 PF13166.6 KLO04715.1 - 9.5 4.7 17.1 1.8 7.1 13.7 1.5 2 0 0 2 2 2 0 AAA domain B_lectin PF01453.24 KLO04717.1 - 0.083 13.4 0.0 0.16 12.5 0.0 1.3 1 1 0 1 1 1 0 D-mannose binding lectin F-box-like PF12937.7 KLO04718.1 - 0.00032 20.5 0.7 0.00096 19.0 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO04718.1 - 1.4 8.9 5.6 0.63 10.0 2.2 2.3 2 0 0 2 2 2 0 F-box domain ING PF12998.7 KLO04720.1 - 0.007 16.9 0.0 0.026 15.1 0.0 1.9 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding GPI-anchored PF10342.9 KLO04724.1 - 0.012 16.4 0.1 0.015 16.1 0.1 1.2 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ATG11 PF10377.9 KLO04725.1 - 0.031 14.4 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 11 CDC48_2 PF02933.17 KLO04725.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Integrase_H2C2 PF17921.1 KLO04726.1 - 3.3e-17 62.4 2.8 4.5e-17 61.9 2.8 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KLO04726.1 - 0.00012 22.2 0.8 0.00022 21.4 0.8 1.4 1 0 0 1 1 1 1 H2C2 zinc finger CMS1 PF14617.6 KLO04729.1 - 0.82 9.0 3.2 1.8 7.8 3.2 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Glycogen_syn PF05693.13 KLO04732.1 - 0 1103.2 0.0 0 1102.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KLO04732.1 - 4.7e-07 29.5 0.0 6.3e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KLO04732.1 - 6.8e-07 29.2 0.0 2.2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 KLO04732.1 - 3.3e-06 27.6 0.0 0.0013 19.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KLO04732.1 - 8.8e-05 23.0 0.0 0.00019 21.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KLO04732.1 - 0.00012 22.2 0.4 0.00021 21.3 0.4 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Hexapep PF00132.24 KLO04740.1 - 9.3e-12 44.2 20.8 8e-07 28.5 0.9 4.6 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KLO04740.1 - 3e-06 26.9 14.4 0.00061 19.5 0.5 3.9 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KLO04740.1 - 1.2e-05 24.4 0.0 1.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 L-fucokinase KDZ PF18758.1 KLO04743.1 - 1.1e-43 149.5 0.6 2e-43 148.6 0.3 1.6 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO04743.1 - 1.6e-17 63.6 0.1 3.2e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO04743.1 - 0.00056 20.0 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases HP1451_C PF18472.1 KLO04743.1 - 0.07 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 HP1451 C-terminal domain TPR_5 PF12688.7 KLO04743.1 - 0.28 11.4 1.0 1.2 9.4 0.5 2.1 2 0 0 2 2 2 0 Tetratrico peptide repeat XPG_I PF00867.18 KLO04744.1 - 9.9e-16 57.9 0.0 3.3e-15 56.2 0.0 1.9 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KLO04744.1 - 0.0017 18.8 0.0 0.0026 18.2 0.0 1.2 1 0 0 1 1 1 1 XPG N-terminal domain DUF3844 PF12955.7 KLO04745.1 - 0.44 10.7 3.2 0.27 11.4 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) Ribosomal_S8 PF00410.19 KLO04746.1 - 1.8e-18 66.7 0.0 2.7e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Msap1 PF17077.5 KLO04746.1 - 0.071 12.3 0.0 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 Mitotic spindle associated protein SHE1 DUF5524 PF17662.1 KLO04747.1 - 0.019 14.4 0.5 0.031 13.6 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5524) Retrotrans_gag PF03732.17 KLO04749.1 - 0.0047 17.2 3.7 0.0072 16.6 0.6 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein LRR_4 PF12799.7 KLO04751.1 - 0.0056 17.1 7.4 0.024 15.1 0.2 4.2 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) DUF3759 PF12585.8 KLO04752.1 - 0.00056 19.9 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) CAP_N PF01213.19 KLO04752.1 - 6.7 6.1 12.0 11 5.4 12.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HIT PF01230.23 KLO04754.1 - 1.3e-22 80.3 0.3 1.7e-22 80.0 0.3 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KLO04754.1 - 1.7e-11 44.6 0.2 2.1e-11 44.3 0.2 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KLO04754.1 - 2.9e-05 23.9 0.0 4.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 NOT2_3_5 PF04153.18 KLO04755.1 - 1.7e-28 99.3 1.2 1.7e-28 99.3 1.2 1.8 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family ENTH PF01417.20 KLO04756.1 - 2.5e-42 143.9 0.2 3.6e-42 143.3 0.2 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KLO04756.1 - 0.0039 16.2 0.1 0.0062 15.6 0.1 1.3 1 0 0 1 1 1 1 ANTH domain DUF2441 PF10386.9 KLO04756.1 - 0.012 15.6 0.2 0.021 14.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) GRP PF07172.11 KLO04756.1 - 0.026 15.2 15.3 0.026 15.2 15.3 2.4 3 0 0 3 3 3 0 Glycine rich protein family F1F0-ATPsyn_F PF10791.9 KLO04757.1 - 2.7e-28 98.3 0.0 3.1e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KLO04757.1 - 0.1 13.0 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f SQS_PSY PF00494.19 KLO04758.1 - 2.5e-18 66.5 0.0 3e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Complex1_LYR PF05347.15 KLO04765.1 - 1.6e-10 40.8 2.4 2.1e-10 40.5 2.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KLO04765.1 - 0.18 12.4 2.6 1.8 9.2 0.2 2.1 1 1 1 2 2 2 0 Complex1_LYR-like zf-MYND PF01753.18 KLO04772.1 - 7.5e-06 25.9 8.5 1.9e-05 24.6 8.5 1.7 1 0 0 1 1 1 1 MYND finger Glyoxalase PF00903.25 KLO04773.1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily F-box-like PF12937.7 KLO04773.1 - 0.18 11.7 1.7 0.51 10.3 0.2 2.7 2 0 0 2 2 2 0 F-box-like zf-MYND PF01753.18 KLO04774.1 - 0.011 15.8 14.2 0.02 15.0 14.2 1.4 1 0 0 1 1 1 0 MYND finger CENP-B_dimeris PF09026.10 KLO04775.1 - 0.0052 17.2 9.4 0.0052 17.2 9.4 2.5 2 0 0 2 2 2 1 Centromere protein B dimerisation domain Roughex PF06020.11 KLO04775.1 - 0.11 11.6 7.5 0.2 10.7 7.5 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Spt5-NGN PF03439.13 KLO04776.1 - 1.9e-11 43.7 0.0 3.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section SH3_15 PF18346.1 KLO04776.1 - 0.11 12.9 0.0 0.52 10.7 0.0 2.3 1 1 0 1 1 1 0 Mind bomb SH3 repeat domain KOW PF00467.29 KLO04776.1 - 0.35 10.9 11.9 0.093 12.7 0.4 3.5 3 0 0 3 3 3 0 KOW motif SH3_13 PF18335.1 KLO04776.1 - 0.4 10.6 1.1 2.6 8.0 0.6 2.4 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain zf-C2H2_7 PF15269.6 KLO04776.1 - 0.4 10.8 3.3 0.96 9.6 3.3 1.6 1 0 0 1 1 1 0 Zinc-finger CDC45 PF02724.14 KLO04776.1 - 1.3 7.2 5.7 1.9 6.7 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC_3 PF13917.6 KLO04779.1 - 0.025 14.5 0.4 0.045 13.7 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Phage_int_SAM_3 PF14659.6 KLO04780.1 - 0.02 15.2 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PNP_phzG_C PF10590.9 KLO04782.1 - 0.1 12.7 0.2 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region CxC2 PF18803.1 KLO04787.1 - 3.9e-30 104.2 0.1 8.5e-30 103.1 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO04787.1 - 3.4e-07 30.4 0.0 3.4e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases YlbD_coat PF14071.6 KLO04789.1 - 0.028 14.7 0.1 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 Putative coat protein KOW PF00467.29 KLO04790.1 - 1.8e-13 49.9 24.7 0.0024 17.8 0.3 7.0 6 0 0 6 6 6 5 KOW motif Spt5-NGN PF03439.13 KLO04790.1 - 3.5e-10 39.6 0.0 1.1e-09 38.1 0.0 1.9 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF3912 PF13051.6 KLO04790.1 - 2.9e-05 24.2 0.3 0.0014 18.8 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3912) SOG2 PF10428.9 KLO04790.1 - 0.23 10.6 3.3 0.48 9.6 3.3 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4438 PF14505.6 KLO04790.1 - 2.7 6.9 7.3 12 4.8 0.0 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF4438) Cwf_Cwc_15 PF04889.12 KLO04796.1 - 0.0066 16.2 14.1 0.017 14.8 14.1 1.6 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 KLO04796.1 - 0.023 14.6 7.0 0.071 13.0 7.0 1.9 1 0 0 1 1 1 0 Sigma-70, non-essential region YL1 PF05764.13 KLO04796.1 - 0.12 12.5 22.4 0.072 13.2 19.5 1.8 1 1 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KLO04796.1 - 0.49 8.6 11.9 0.71 8.1 11.9 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KLO04796.1 - 2.5 7.3 18.1 5 6.3 18.1 1.4 1 0 0 1 1 1 0 NOA36 protein Glypican PF01153.19 KLO04796.1 - 2.6 6.8 4.1 4.1 6.1 4.1 1.2 1 0 0 1 1 1 0 Glypican Nop14 PF04147.12 KLO04796.1 - 3.8 5.6 18.3 5.6 5.0 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family CBM_19 PF03427.13 KLO04797.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) WD40 PF00400.32 KLO04798.1 - 0.00011 23.0 4.5 0.011 16.6 0.4 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO04798.1 - 0.015 15.6 0.1 10 6.5 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain gag-asp_proteas PF13975.6 KLO04804.1 - 2.6e-05 24.7 0.0 5.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KLO04804.1 - 0.00023 21.7 0.0 0.00062 20.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Bromodomain PF00439.25 KLO04806.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain F-box-like PF12937.7 KLO04808.1 - 0.1 12.5 0.1 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 KLO04811.1 - 0.00026 20.8 0.0 0.00076 19.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like DUF1993 PF09351.10 KLO04811.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) F-box-like PF12937.7 KLO04812.1 - 0.0099 15.8 0.1 0.025 14.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO04812.1 - 0.18 12.2 2.0 18 5.9 0.4 3.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO04813.1 - 2.8e-05 23.9 0.1 9.1e-05 22.3 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO04813.1 - 0.089 13.3 0.5 26 5.4 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO04815.1 - 1.1e-08 34.8 0.1 4.5e-07 29.7 0.0 3.0 3 0 0 3 3 3 1 F-box-like AsnC_trans_reg2 PF17805.1 KLO04815.1 - 0.18 12.0 0.2 1.7 8.9 0.0 2.5 3 0 0 3 3 3 0 AsnC-like ligand binding domain F-box-like PF12937.7 KLO04816.1 - 5.8e-09 35.7 0.2 1.8e-08 34.1 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.13 KLO04816.1 - 0.017 15.7 0.2 0.065 13.9 0.2 2.1 1 0 0 1 1 1 0 Leucine Rich Repeat F-box PF00646.33 KLO04816.1 - 0.032 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 F-box domain MMU163 PF17119.5 KLO04816.1 - 0.038 13.1 0.7 0.18 10.9 0.2 1.9 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Polysacc_lyase PF14099.6 KLO04817.1 - 0.092 12.6 0.8 0.18 11.6 0.8 1.5 1 1 0 1 1 1 0 Polysaccharide lyase Pico_P1A PF02226.16 KLO04818.1 - 0.44 10.6 2.6 2.8 8.0 0.2 2.1 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) FAS_I_H PF18314.1 KLO04820.1 - 0.019 14.6 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain SLT PF01464.20 KLO04822.1 - 5.5e-12 45.4 0.0 9.4e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain ERO1 PF04137.15 KLO04823.1 - 1.1e-127 426.0 0.0 1.4e-127 425.8 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ShK PF01549.24 KLO04823.1 - 0.17 12.5 1.5 0.34 11.5 0.2 2.2 2 0 0 2 2 2 0 ShK domain-like Phage_integrase PF00589.22 KLO04825.1 - 0.00088 19.1 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Phage integrase family XPG_I PF00867.18 KLO04826.1 - 1e-13 51.4 0.0 1.7e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 XPG I-region Cauli_VI PF01693.16 KLO04828.1 - 0.00015 22.0 0.0 0.00034 20.9 0.0 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin KDZ PF18758.1 KLO04830.1 - 1.1e-39 136.4 0.1 1.6e-39 135.8 0.1 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO04830.1 - 7.4e-23 80.8 1.6 9.6e-16 57.9 0.1 2.6 1 1 1 2 2 2 2 CxC2 like cysteine cluster associated with KDZ transposases CEBP_ZZ PF16366.5 KLO04830.1 - 0.041 14.1 1.4 0.11 12.8 1.4 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-UBR PF02207.20 KLO04830.1 - 1.7 8.9 7.6 6.8 6.9 0.2 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) TF_Zn_Ribbon PF08271.12 KLO04830.1 - 3.7 7.1 10.1 5.7 6.5 2.6 3.6 3 0 0 3 3 3 0 TFIIB zinc-binding CLASP_N PF12348.8 KLO04831.1 - 9.5e-68 228.2 0.0 1e-57 195.3 0.0 3.8 3 1 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 KLO04831.1 - 6.4e-06 26.0 0.0 2.8 8.4 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KLO04831.1 - 7.6e-06 26.1 0.0 0.11 12.6 0.1 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KLO04831.1 - 0.0084 16.6 0.5 4.2 8.0 0.0 4.7 4 1 0 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.20 KLO04831.1 - 0.074 11.6 0.1 3.3 6.2 0.0 3.1 4 0 0 4 4 4 0 Adaptin N terminal region TPR_20 PF14561.6 KLO04831.1 - 0.13 12.6 0.6 18 5.8 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Rhomboid PF01694.22 KLO04832.1 - 2.9e-29 102.0 8.4 4.8e-29 101.3 8.4 1.4 1 0 0 1 1 1 1 Rhomboid family SPO11_like PF03533.14 KLO04833.1 - 0.086 12.9 0.1 0.66 10.1 0.0 2.4 2 0 0 2 2 2 0 SPO11 homologue Sedlin_N PF04628.13 KLO04834.1 - 7.4e-31 107.0 0.5 2.7e-24 85.7 0.2 2.9 2 1 0 2 2 2 2 Sedlin, N-terminal conserved region Sybindin PF04099.12 KLO04834.1 - 1e-05 25.5 0.0 0.047 13.6 0.0 2.4 3 0 0 3 3 3 2 Sybindin-like family gag-asp_proteas PF13975.6 KLO04836.1 - 3.7e-06 27.4 0.1 1.3e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Herpes_ORF11 PF04797.13 KLO04836.1 - 0.00014 20.8 0.0 0.00022 20.1 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus dUTPase protein Asp_protease_2 PF13650.6 KLO04836.1 - 0.00022 21.8 0.0 0.00046 20.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KLO04836.1 - 0.0088 16.3 0.5 0.048 14.0 0.1 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 KLO04836.1 - 0.092 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase Mdv1 PF11542.8 KLO04843.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial division protein 1 DUF4218 PF13960.6 KLO04848.1 - 0.00059 19.4 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.14 KLO04849.1 - 0.00014 21.2 0.0 0.00016 21.0 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 BTB PF00651.31 KLO04855.1 - 7.3e-07 29.4 0.1 5.9e-05 23.3 0.0 3.0 3 1 0 3 3 3 1 BTB/POZ domain BTB PF00651.31 KLO04856.1 - 4.7e-05 23.6 0.4 0.00032 20.9 0.4 2.4 1 1 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 KLO04857.1 - 0.07 13.0 0.1 0.3 11.0 0.2 2.1 2 0 0 2 2 2 0 F-box-like WD40 PF00400.32 KLO04860.1 - 5.9 7.9 6.6 1.9e+02 3.2 0.0 4.1 4 1 0 4 4 4 0 WD domain, G-beta repeat Plavaka PF18759.1 KLO04861.1 - 2.4e-13 50.0 0.0 4e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase HTH_39 PF14090.6 KLO04861.1 - 0.049 13.4 0.0 3.1 7.6 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Glyco_transf_11 PF01531.16 KLO04862.1 - 0.062 12.5 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 11 VIR_N PF15912.5 KLO04862.1 - 0.92 9.0 8.3 0.058 13.0 3.2 1.5 2 0 0 2 2 2 0 Virilizer, N-terminal DUF4418 PF14387.6 KLO04863.1 - 0.038 14.2 0.3 0.07 13.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) Fcf1 PF04900.12 KLO04864.1 - 3.1e-33 114.1 0.1 4.4e-33 113.6 0.1 1.2 1 0 0 1 1 1 1 Fcf1 S36_mt PF10937.8 KLO04865.1 - 1.9 10.1 6.9 0.64 11.6 2.4 2.1 1 1 1 2 2 2 0 Ribosomal protein S36, mitochondrial UPF0176_N PF17773.1 KLO04867.1 - 0.043 14.2 0.0 0.052 13.9 0.0 1.2 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain IGR PF09597.10 KLO04868.1 - 0.31 11.2 2.1 21 5.3 0.1 2.4 2 0 0 2 2 2 0 IGR protein motif LRIF1 PF15741.5 KLO04870.1 - 0.27 9.7 1.8 0.28 9.7 1.8 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Phosphodiest PF01663.22 KLO04873.1 - 4.4e-12 46.3 0.0 7.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KLO04873.1 - 0.0019 17.6 0.3 0.003 17.0 0.3 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KLO04873.1 - 0.011 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Sulfatase DUF3084 PF11283.8 KLO04873.1 - 0.027 14.4 0.3 8.4 6.5 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) Cyclin_N PF00134.23 KLO04875.1 - 0.011 15.5 0.1 0.092 12.5 0.1 2.5 1 1 0 1 1 1 0 Cyclin, N-terminal domain DUF4419 PF14388.6 KLO04876.1 - 3.2e-96 322.3 0.0 1e-93 314.1 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4419) Topo_Zn_Ribbon PF08272.11 KLO04876.1 - 0.31 10.7 1.4 0.73 9.5 1.4 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like IMD PF08397.11 KLO04877.1 - 0.13 11.6 1.9 0.26 10.7 1.9 1.4 1 1 0 1 1 1 0 IRSp53/MIM homology domain MaoC_dehydrat_N PF13452.6 KLO04878.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase PEX11 PF05648.14 KLO04879.1 - 0.016 14.7 0.1 0.041 13.3 0.1 1.7 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) TctA PF01970.16 KLO04879.1 - 0.016 14.0 0.6 0.024 13.4 0.6 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family SUR7 PF06687.12 KLO04879.1 - 0.5 10.0 9.9 0.69 9.5 0.6 2.3 1 1 1 2 2 2 0 SUR7/PalI family DUF4231 PF14015.6 KLO04879.1 - 1.5 9.3 5.6 8.4 6.9 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2721 PF11026.8 KLO04879.1 - 2.4 8.0 12.5 0.76 9.7 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) GT87 PF09594.10 KLO04880.1 - 2.5 7.8 11.5 0.98 9.1 0.9 2.5 2 1 0 2 2 2 0 Glycosyltransferase family 87 DUF3272 PF11676.8 KLO04881.1 - 0.029 14.6 1.2 5.8 7.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) Chromo PF00385.24 KLO04882.1 - 0.0059 16.5 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PIF1 PF05970.14 KLO04884.1 - 1.2e-15 57.5 0.6 1.5e-15 57.3 0.6 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KLO04884.1 - 1.5e-13 50.9 0.1 1.9e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO04884.1 - 1.5e-09 38.4 0.1 3.1e-09 37.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KLO04884.1 - 0.0027 17.7 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 KLO04884.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ResIII PF04851.15 KLO04884.1 - 0.013 15.5 0.2 0.026 14.5 0.2 1.5 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit MeaB PF03308.16 KLO04884.1 - 0.016 14.2 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KLO04884.1 - 0.017 15.5 0.1 0.033 14.6 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KLO04884.1 - 0.025 14.3 0.2 0.051 13.3 0.0 1.6 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KLO04884.1 - 0.038 13.5 1.0 0.11 12.0 0.8 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KLO04884.1 - 0.04 14.3 0.0 0.046 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Helitron_like_N PF14214.6 KLO04888.1 - 1.8e-26 93.5 0.2 2.1e-26 93.3 0.2 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus zf-Sec23_Sec24 PF04810.15 KLO04890.1 - 0.62 10.2 0.0 0.62 10.2 0.0 2.5 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF4449 PF14613.6 KLO04892.1 - 0.074 13.2 0.1 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Chromo PF00385.24 KLO04893.1 - 2.1e-08 34.0 0.0 2.6e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 KLO04896.1 - 9.4e-07 29.3 0.0 7.2e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KLO04896.1 - 7e-05 23.4 0.0 0.00016 22.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KLO04896.1 - 0.018 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 KLO04897.1 - 0.005 17.1 1.9 0.0081 16.4 0.7 2.0 2 1 0 2 2 2 1 Retrotransposon gag protein GSH_synth_ATP PF03917.17 KLO04901.1 - 1.2e-72 244.8 0.0 1.4e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KLO04901.1 - 2.7e-32 111.3 0.0 4.1e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Fe-S_biosyn PF01521.20 KLO04902.1 - 3.1e-12 46.7 0.0 4.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Spt5-NGN PF03439.13 KLO04909.1 - 5.3e-08 32.7 1.2 3.1e-07 30.2 0.0 2.7 3 0 0 3 3 3 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KLO04909.1 - 0.091 12.7 15.5 0.11 12.5 0.7 4.5 5 0 0 5 5 5 0 KOW motif DUF3912 PF13051.6 KLO04909.1 - 0.19 12.0 0.2 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) HMG_box_2 PF09011.10 KLO04910.1 - 0.00014 22.4 1.8 0.0007 20.1 1.6 2.3 1 1 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KLO04910.1 - 0.0043 17.4 1.9 0.05 14.0 0.5 3.2 3 0 0 3 3 3 1 HMG (high mobility group) box AT_hook PF02178.19 KLO04910.1 - 0.045 13.6 4.3 0.18 11.8 4.3 2.1 1 0 0 1 1 1 0 AT hook motif PseudoU_synth_1 PF01416.20 KLO04912.1 - 1.2e-09 38.5 0.0 1.3e-07 32.0 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase Pkinase_fungal PF17667.1 KLO04913.1 - 5.7e-72 242.7 0.3 1e-71 241.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 KLO04913.1 - 9e-06 25.2 0.1 0.00014 21.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KLO04913.1 - 1.9e-05 24.1 0.3 0.031 13.6 0.2 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KLO04913.1 - 0.023 14.0 0.2 0.052 12.8 0.2 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase DUF805 PF05656.14 KLO04914.1 - 0.012 16.0 0.9 0.031 14.7 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF2304 PF10066.9 KLO04914.1 - 2.3 8.5 7.3 0.52 10.5 3.2 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Glyco_hydro_47 PF01532.20 KLO04917.1 - 1e-137 459.8 0.0 1.2e-137 459.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Shisa PF13908.6 KLO04918.1 - 0.4 10.9 1.6 0.56 10.4 1.6 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Herpes_TK PF00693.18 KLO04920.1 - 0.081 12.1 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus Cellulose_synt PF03552.14 KLO04929.1 - 0.11 11.0 0.3 0.18 10.3 0.3 1.2 1 0 0 1 1 1 0 Cellulose synthase ThrE PF06738.12 KLO04929.1 - 0.62 9.4 3.8 0.91 8.8 0.3 2.3 2 0 0 2 2 2 0 Putative threonine/serine exporter KDZ PF18758.1 KLO04935.1 - 5.9e-49 166.7 0.0 9.8e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO04935.1 - 2.7e-35 120.8 0.1 4.9e-35 119.9 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF5004 PF16395.5 KLO04937.1 - 0.18 11.8 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5004) F-box-like PF12937.7 KLO04939.1 - 4.9e-10 39.1 0.9 4.9e-10 39.1 0.9 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO04939.1 - 0.93 9.5 7.7 0.2 11.6 2.8 2.4 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO04940.1 - 1e-12 47.7 3.1 2.4e-11 43.3 0.5 3.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO04940.1 - 0.022 14.6 1.2 9.1 6.3 0.0 2.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO04941.1 - 1e-10 41.3 6.2 2.5e-10 40.1 3.9 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO04941.1 - 0.021 14.7 6.7 1.3 9.0 0.7 3.1 3 0 0 3 3 3 0 F-box domain GMC_oxred_N PF00732.19 KLO04945.1 - 9.3e-65 218.9 0.0 1.2e-64 218.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO04945.1 - 3.4e-32 111.9 0.0 5.9e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KLO04945.1 - 7.9e-05 22.8 0.1 0.00063 19.9 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO04945.1 - 0.00012 21.8 0.9 0.00046 19.9 0.4 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KLO04945.1 - 0.00024 20.3 0.2 0.00035 19.8 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KLO04945.1 - 0.00024 20.3 0.4 0.00069 18.8 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KLO04945.1 - 0.00083 18.7 0.1 0.0017 17.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KLO04945.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO04945.1 - 0.024 13.4 0.1 0.05 12.3 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KLO04945.1 - 0.083 12.1 0.1 0.33 10.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KLO04946.1 - 4e-66 223.4 0.0 5.1e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO04946.1 - 6.8e-34 117.5 0.0 1.3e-33 116.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KLO04946.1 - 0.0039 16.5 0.1 0.019 14.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family EF-1_beta_acid PF10587.9 KLO04947.1 - 1.5 9.4 5.0 3.7 8.1 5.0 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region F-box-like PF12937.7 KLO04949.1 - 9.8e-05 22.2 0.0 0.00029 20.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF948 PF06103.11 KLO04951.1 - 0.00027 21.1 1.2 0.00027 21.1 1.2 1.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) COG6 PF06419.11 KLO04951.1 - 0.0008 17.8 1.6 0.001 17.4 1.6 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 KLO04951.1 - 0.00095 19.3 1.0 0.0013 18.9 1.0 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.9 KLO04951.1 - 0.002 17.3 0.4 0.0024 17.0 0.4 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 EzrA PF06160.12 KLO04951.1 - 0.0034 15.6 1.5 0.0044 15.3 1.5 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 KLO04951.1 - 0.024 14.7 2.5 0.083 13.0 1.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Tup_N PF08581.10 KLO04951.1 - 0.03 14.6 0.2 0.046 14.0 0.2 1.3 1 0 0 1 1 1 0 Tup N-terminal Med9 PF07544.13 KLO04951.1 - 0.085 13.0 1.2 0.13 12.3 1.2 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 VP4_helical PF17478.2 KLO04951.1 - 0.16 11.4 1.8 0.2 11.1 1.8 1.1 1 0 0 1 1 1 0 Rotavirus VP4 helical domain Ribosomal_S13_N PF08069.12 KLO04951.1 - 0.35 10.9 2.1 2.5 8.2 0.1 2.5 2 1 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain CortBP2 PF09727.9 KLO04952.1 - 0.0016 18.4 2.4 0.002 18.1 2.4 1.1 1 0 0 1 1 1 1 Cortactin-binding protein-2 APG6_N PF17675.1 KLO04952.1 - 0.0035 17.9 0.4 0.005 17.4 0.4 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Med4 PF10018.9 KLO04952.1 - 0.0093 15.7 0.9 0.013 15.2 0.9 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 AAA_13 PF13166.6 KLO04952.1 - 0.012 14.3 0.1 0.013 14.2 0.1 1.0 1 0 0 1 1 1 0 AAA domain TMCO5 PF14992.6 KLO04952.1 - 0.013 15.1 2.2 0.016 14.8 2.2 1.1 1 0 0 1 1 1 0 TMCO5 family zf-C4H2 PF10146.9 KLO04952.1 - 0.069 13.5 2.8 0.098 13.0 2.8 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4140 PF13600.6 KLO04952.1 - 0.077 13.4 2.0 0.13 12.7 2.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.21 KLO04952.1 - 0.078 13.1 2.4 0.14 12.3 2.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor PCRF PF03462.18 KLO04952.1 - 0.29 11.0 4.1 0.39 10.6 4.1 1.1 1 0 0 1 1 1 0 PCRF domain THOC7 PF05615.13 KLO04952.1 - 0.42 10.9 5.1 0.97 9.7 5.1 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 Lge1 PF11488.8 KLO04952.1 - 0.46 10.7 4.6 1.6 9.0 4.6 1.9 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Spc24 PF08286.11 KLO04952.1 - 1.4 9.2 5.4 1.6 9.0 3.9 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ABC_tran_CTD PF16326.5 KLO04952.1 - 3.9 7.8 7.8 6.5 7.1 1.7 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain Abhydrolase_3 PF07859.13 KLO04953.1 - 1.6e-12 47.7 0.0 1.9e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO04953.1 - 1.4e-10 40.6 0.0 1.8e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KLO04953.1 - 0.0043 17.7 1.0 0.0052 17.4 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KLO04953.1 - 0.033 13.8 0.8 3.8 7.1 0.1 2.1 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 KLO04953.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KLO04953.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KLO04953.1 - 0.15 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein zf_C2H2_6 PF18450.1 KLO04954.1 - 0.22 11.3 1.1 0.57 9.9 1.1 1.7 1 0 0 1 1 1 0 Zinc Finger domain ETF_alpha PF00766.19 KLO04956.1 - 0.067 13.2 0.0 1.3 9.1 0.0 2.3 2 1 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain Peptidase_C12 PF01088.21 KLO04957.1 - 2.1e-15 57.0 0.0 2.5e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Med31 PF05669.12 KLO04958.1 - 6.4e-37 125.5 5.7 8.5e-37 125.1 5.7 1.1 1 0 0 1 1 1 1 SOH1 Nod_GRP PF07806.11 KLO04958.1 - 0.0019 18.0 3.7 0.0097 15.7 0.1 2.4 2 0 0 2 2 2 1 Nodule-specific GRP repeat KDZ PF18758.1 KLO04959.1 - 7.8e-54 182.6 0.0 1.3e-53 181.9 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO04959.1 - 6e-29 100.3 0.1 1.1e-28 99.5 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO04959.1 - 0.00092 19.3 0.0 0.0024 18.0 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases IclR PF01614.18 KLO04959.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial transcriptional regulator Cauli_VI PF01693.16 KLO04960.1 - 0.0013 19.0 0.2 0.0061 16.8 0.2 2.0 1 1 0 1 1 1 1 Caulimovirus viroplasmin Peroxidase_ext PF11895.8 KLO04962.1 - 7.3e-28 96.3 2.5 1.7e-27 95.2 2.5 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 KLO04962.1 - 8.2e-27 94.4 0.0 1.6e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Peroxidase zf-CCHC PF00098.23 KLO04965.1 - 0.0027 17.7 0.6 0.0027 17.7 0.6 1.8 2 0 0 2 2 1 1 Zinc knuckle Asp_protease_2 PF13650.6 KLO04965.1 - 0.0047 17.6 0.0 0.013 16.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Cwf_Cwc_15 PF04889.12 KLO04965.1 - 0.036 13.8 6.6 0.069 12.9 6.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein gag-asp_proteas PF13975.6 KLO04965.1 - 0.064 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4614 PF15391.6 KLO04965.1 - 0.23 11.5 2.7 0.47 10.4 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Nop14 PF04147.12 KLO04965.1 - 0.26 9.5 8.3 0.36 9.0 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KLO04965.1 - 0.39 10.0 13.3 0.013 14.8 7.3 1.5 2 0 0 2 2 2 0 BUD22 CCDC106 PF15794.5 KLO04965.1 - 0.48 10.1 6.0 0.92 9.2 6.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 zf-CCHC_4 PF14392.6 KLO04965.1 - 0.51 10.1 6.5 0.046 13.5 1.6 1.8 2 0 0 2 2 2 0 Zinc knuckle CDC45 PF02724.14 KLO04965.1 - 0.64 8.2 8.8 0.98 7.6 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC_2 PF13696.6 KLO04965.1 - 2.5 8.0 6.2 0.37 10.7 1.3 2.0 2 0 0 2 2 2 0 Zinc knuckle Apt1 PF10351.9 KLO04965.1 - 2.9 6.7 6.2 4.9 5.9 6.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain KDZ PF18758.1 KLO04968.1 - 6.1e-36 124.1 0.0 1.2e-35 123.2 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Herpes_UL56 PF04534.12 KLO04969.1 - 0.012 15.2 0.2 0.02 14.4 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein zf-MYND PF01753.18 KLO04974.1 - 3.5e-05 23.8 16.2 0.00013 21.9 16.2 2.0 1 1 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO04975.1 - 1e-06 28.7 10.0 2e-06 27.7 10.0 1.5 1 0 0 1 1 1 1 MYND finger IL2 PF00715.17 KLO04976.1 - 0.017 15.0 0.3 0.039 13.9 0.1 1.7 2 0 0 2 2 2 0 Interleukin 2 LRR_4 PF12799.7 KLO04976.1 - 0.15 12.5 14.6 2.2 8.8 1.0 4.9 2 1 1 5 5 5 0 Leucine Rich repeats (2 copies) MCM_OB PF17207.3 KLO04981.1 - 5.5e-19 68.2 0.0 9.4e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM PF00493.23 KLO04981.1 - 0.096 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Paralemmin PF03285.15 KLO04982.1 - 0.095 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Paralemmin Cyclin_N PF00134.23 KLO04983.1 - 6.5e-05 22.7 0.0 7.1e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KLO04983.1 - 0.00015 22.2 0.0 0.00015 22.2 0.0 1.0 1 0 0 1 1 1 1 Cyclin MFS_1 PF07690.16 KLO04984.1 - 4.6e-18 65.3 14.7 4.6e-18 65.3 14.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2512 PF10710.9 KLO04985.1 - 4.1 7.1 13.0 0.55 9.9 4.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2512) Ribosomal_L18A PF01775.17 KLO04987.1 - 2.2e-53 179.5 0.4 2.7e-53 179.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A zf-TRAF PF02176.18 KLO04989.1 - 1.1 10.0 6.0 1 10.1 0.6 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger ING PF12998.7 KLO04990.1 - 2.1e-13 50.7 0.1 3.1e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KLO04990.1 - 6.4e-07 29.2 6.5 1e-06 28.5 6.5 1.3 1 0 0 1 1 1 1 PHD-finger LRRFIP PF09738.9 KLO04990.1 - 0.0052 16.3 1.3 0.043 13.3 1.3 2.0 1 1 0 1 1 1 1 LRRFIP family PHD_2 PF13831.6 KLO04990.1 - 0.027 14.0 0.8 0.049 13.2 0.8 1.4 1 0 0 1 1 1 0 PHD-finger Chitin_synth_2 PF03142.15 KLO04991.1 - 1.2e-281 934.9 0.1 1.6e-281 934.5 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KLO04991.1 - 1.1e-11 45.1 0.3 3.1e-11 43.6 0.3 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KLO04991.1 - 1.4e-10 41.5 0.0 1.9e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KLO04991.1 - 0.00054 19.5 0.0 0.03 13.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KLO04991.1 - 0.017 14.9 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 TPR_9 PF13371.6 KLO04992.1 - 0.0014 18.7 0.1 0.0014 18.7 0.1 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KLO04993.1 - 6.8e-23 81.3 0.0 8.2e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO04993.1 - 2.3e-20 73.0 0.0 2.7e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KLO04993.1 - 0.00025 20.5 0.0 0.00033 20.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO04993.1 - 0.00036 20.5 0.0 0.00039 20.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO04993.1 - 0.007 15.2 0.0 0.0075 15.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase EcKinase PF02958.20 KLO04993.1 - 0.0087 15.4 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Kinase-like PF14531.6 KLO04993.1 - 0.011 15.1 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KLO04993.1 - 0.026 14.1 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 RIO1 family NSP2-B_epitope PF14757.6 KLO04993.1 - 0.14 11.8 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein HTH_32 PF13565.6 KLO04994.1 - 1.5e-07 31.9 0.1 2.3e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 KLO04994.1 - 1e-06 28.3 0.1 8.7e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KLO04994.1 - 2.7e-05 23.8 0.3 0.0015 18.2 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KLO04994.1 - 0.0036 17.5 0.0 0.0082 16.4 0.0 1.6 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 KLO04994.1 - 0.0061 16.6 0.1 0.054 13.5 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_IS630 PF01710.16 KLO04994.1 - 0.022 14.8 0.1 1.4 9.0 0.0 2.1 1 1 1 2 2 2 0 Transposase FUR PF01475.19 KLO04994.1 - 0.034 14.3 0.0 2 8.6 0.0 2.1 2 0 0 2 2 2 0 Ferric uptake regulator family PadR PF03551.14 KLO04994.1 - 0.16 11.9 0.0 6.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DDE_3 PF13358.6 KLO04995.1 - 4.6e-10 39.4 0.0 5e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3894 PF13033.6 KLO04995.1 - 0.039 14.1 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3894) DDE_3 PF13358.6 KLO04996.1 - 1.3e-07 31.5 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SKA2 PF16740.5 KLO04998.1 - 0.035 13.9 0.2 0.1 12.4 0.2 1.7 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 HTH_16 PF12645.7 KLO04998.1 - 0.22 11.6 1.1 0.85 9.7 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain ZapB PF06005.12 KLO04998.1 - 2.6 8.6 5.8 0.24 11.9 0.6 1.9 2 0 0 2 2 2 0 Cell division protein ZapB Pkinase PF00069.25 KLO04999.1 - 0.051 12.9 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KLO04999.1 - 0.052 12.8 0.0 0.063 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Zn_clus PF00172.18 KLO05000.1 - 1.1 9.5 14.4 1.4 9.1 4.3 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 KLO05001.1 - 4e-53 179.8 0.0 1.2e-51 175.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO05001.1 - 3.8e-32 110.9 0.0 2.2e-30 105.2 0.0 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO05001.1 - 6.2e-08 32.8 0.0 1.8e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KLO05001.1 - 0.014 14.2 0.0 0.27 10.0 0.0 2.6 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 GRP PF07172.11 KLO05001.1 - 0.029 15.1 11.2 0.029 15.1 11.2 2.5 2 0 0 2 2 2 0 Glycine rich protein family AAA_19 PF13245.6 KLO05001.1 - 0.083 13.2 0.1 18 5.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF390 PF04094.14 KLO05001.1 - 5.5 5.2 8.3 8.4 4.5 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) zf-MYND PF01753.18 KLO05002.1 - 2.1e-07 30.9 14.9 4.1e-07 30.0 14.9 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO05002.1 - 0.015 15.4 4.3 0.04 14.0 4.3 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KLO05002.1 - 1 9.7 11.4 2.6 8.4 11.4 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KLO05003.1 - 8.1e-09 35.4 9.4 1.6e-08 34.5 9.4 1.5 1 0 0 1 1 1 1 MYND finger Pkinase_C PF00433.24 KLO05004.1 - 0.41 11.4 3.2 0.56 11.0 0.1 3.0 3 0 0 3 3 3 0 Protein kinase C terminal domain E1-E2_ATPase PF00122.20 KLO05005.1 - 7e-23 81.1 0.0 1.8e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KLO05005.1 - 1e-16 61.9 0.0 4e-10 40.3 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KLO05005.1 - 0.0011 19.1 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KLO05005.1 - 0.0095 15.6 0.0 0.027 14.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KLO05005.1 - 0.08 12.7 0.1 0.18 11.5 0.1 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 KLO05005.1 - 0.15 12.1 0.7 0.99 9.5 0.0 2.4 2 0 0 2 2 2 0 P5-type ATPase cation transporter Glucos_trans_II PF14264.6 KLO05005.1 - 3.8 6.8 13.4 0.27 10.5 0.8 2.8 3 0 0 3 3 3 0 Glucosyl transferase GtrII Hydantoinase_B PF02538.14 KLO05006.1 - 1.4e-205 683.6 0.1 1.7e-205 683.4 0.1 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase EF-hand_1 PF00036.32 KLO05007.1 - 5.6e-42 138.2 9.3 9.6e-10 37.3 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KLO05007.1 - 3.3e-35 120.4 1.1 4.6e-17 62.2 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KLO05007.1 - 2.2e-32 110.7 9.5 5.4e-14 51.8 0.2 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KLO05007.1 - 2.6e-31 104.8 5.2 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KLO05007.1 - 9.8e-28 94.4 6.6 1.2e-06 27.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KLO05007.1 - 7.4e-15 55.0 0.1 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KLO05007.1 - 3.6e-09 36.5 0.4 0.00037 20.4 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KLO05007.1 - 1.8e-08 34.7 0.0 0.0017 18.7 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KLO05007.1 - 2.3e-06 27.5 0.0 0.042 13.9 0.0 2.9 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 KLO05007.1 - 1.7e-05 24.9 3.5 0.006 16.7 0.2 3.1 1 1 2 3 3 3 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 KLO05007.1 - 0.00016 21.7 0.5 0.00086 19.4 0.1 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KLO05007.1 - 0.00035 21.4 0.0 0.17 12.8 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 KLO05007.1 - 0.00041 20.3 0.4 0.39 10.6 0.0 3.2 1 1 2 3 3 3 1 Caleosin related protein DUF1103 PF06513.11 KLO05007.1 - 0.00055 19.6 0.6 0.0006 19.5 0.6 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) MotA_activ PF09114.10 KLO05007.1 - 0.0013 18.8 0.3 0.021 14.9 0.0 2.3 1 1 0 2 2 2 1 Transcription factor MotA, activation domain Poly_export PF02563.16 KLO05007.1 - 0.0024 18.1 0.1 0.3 11.4 0.1 3.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis/export protein DUF3349 PF11829.8 KLO05007.1 - 0.005 17.6 0.2 2.7 8.8 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.16 KLO05007.1 - 0.0064 16.8 0.3 4.6 7.6 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF4497 PF14924.6 KLO05007.1 - 0.0077 16.7 0.0 2.3 8.7 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) dCache_2 PF08269.11 KLO05007.1 - 0.022 13.9 0.1 1.9 7.6 0.0 2.3 1 1 0 2 2 2 0 Cache domain TerB PF05099.13 KLO05007.1 - 0.025 14.5 0.1 0.61 10.0 0.0 2.2 1 1 1 2 2 2 0 Tellurite resistance protein TerB SurA_N_2 PF13623.6 KLO05007.1 - 0.031 14.2 0.3 2 8.3 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 KLO05007.1 - 0.033 12.7 0.0 0.034 12.7 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 KLO05007.1 - 0.039 14.3 0.1 9.3 6.7 0.0 2.4 1 1 0 2 2 2 0 EF-hand domain DUF1811 PF08838.10 KLO05007.1 - 0.042 14.1 0.0 9.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) Fe_hyd_lg_C PF02906.14 KLO05007.1 - 0.088 12.5 0.1 0.15 11.7 0.1 1.4 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Spore_III_AB PF09548.10 KLO05007.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Ribosomal_S7e PF01251.18 KLO05010.1 - 4.7e-81 270.9 3.0 5.4e-81 270.7 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e TetR_C_24 PF17932.1 KLO05010.1 - 0.096 13.0 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Abhydrolase_1 PF00561.20 KLO05011.1 - 7.5e-06 25.8 0.0 0.00024 20.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO05011.1 - 0.0041 17.8 0.4 0.0089 16.6 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Bystin PF05291.11 KLO05012.1 - 7.7e-126 419.3 0.0 1e-125 418.9 0.0 1.1 1 0 0 1 1 1 1 Bystin TPR_18 PF13512.6 KLO05012.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3245 PF11595.8 KLO05012.1 - 0.44 11.0 5.7 0.86 10.1 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) GDP_Man_Dehyd PF16363.5 KLO05013.1 - 1.3e-54 185.8 0.0 1.6e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KLO05013.1 - 6.4e-45 153.5 0.0 8.9e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KLO05013.1 - 1e-07 31.4 0.1 0.00069 18.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KLO05013.1 - 1.4e-06 27.5 0.0 2.5e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KLO05013.1 - 0.0001 21.6 0.1 0.0014 17.8 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KLO05013.1 - 0.0064 15.6 0.0 0.009 15.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain MRP-S27 PF10037.9 KLO05015.1 - 0.017 14.0 0.1 0.027 13.4 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DDE_Tnp_4 PF13359.6 KLO05016.1 - 0.0014 18.3 0.1 0.0023 17.6 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Swi6_N PF18530.1 KLO05016.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Swi6 N-terminal domain DUF4419 PF14388.6 KLO05017.1 - 7.1e-07 28.9 0.3 2.8e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4419) Lactamase_B_2 PF12706.7 KLO05018.1 - 0.0003 20.4 0.0 0.00061 19.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zf-C2HC5 PF06221.13 KLO05018.1 - 0.0033 17.4 0.1 0.0078 16.2 0.1 1.6 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type CBM_3 PF00942.18 KLO05018.1 - 0.0049 17.3 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Cellulose binding domain UL45 PF05473.12 KLO05019.1 - 0.0078 15.9 0.2 0.01 15.5 0.2 1.2 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Fungal_trans PF04082.18 KLO05022.1 - 5e-16 58.5 0.6 1.1e-15 57.4 0.6 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Phage_AlpA PF05930.12 KLO05025.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) MFS_1 PF07690.16 KLO05029.1 - 9.4e-16 57.7 33.7 9.4e-16 57.7 33.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KLO05029.1 - 2.6e-11 43.5 3.6 2.6e-11 43.5 3.6 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 zf-LITAF-like PF10601.9 KLO05029.1 - 4.5 7.6 7.6 1.3 9.3 0.1 3.4 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain His_Phos_2 PF00328.22 KLO05030.1 - 3.6e-51 174.7 0.0 4.7e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DDE_3 PF13358.6 KLO05031.1 - 5e-05 23.1 1.0 0.61 9.8 0.4 3.1 2 1 0 2 2 2 2 DDE superfamily endonuclease F-box-like PF12937.7 KLO05033.1 - 1e-10 41.3 0.0 3.4e-10 39.7 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05033.1 - 0.0002 21.1 0.0 0.00073 19.3 0.0 2.1 1 0 0 1 1 1 1 F-box domain DUF1648 PF07853.11 KLO05034.1 - 0.18 11.5 0.1 7.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) F-box-like PF12937.7 KLO05035.1 - 3.3e-06 26.9 0.0 5.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05035.1 - 0.01 15.7 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 0 F-box domain HTH_55 PF18622.1 KLO05035.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 RctB helix turn helix domain Exo_endo_phos PF03372.23 KLO05038.1 - 1.4e-07 31.3 0.1 2.4e-07 30.5 0.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UBX PF00789.20 KLO05040.1 - 1.7e-11 44.2 0.5 3.1e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 KLO05040.1 - 1.3e-05 25.0 0.9 2.2e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 UBA/TS-N domain DUF4805 PF16063.5 KLO05040.1 - 0.11 11.8 6.1 0.09 12.1 4.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4805) zf-C2H2_2 PF12756.7 KLO05040.1 - 0.13 12.6 0.3 0.29 11.5 0.3 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Herpes_UL25 PF01499.16 KLO05040.1 - 0.68 8.4 6.5 0.58 8.6 5.5 1.4 1 1 0 1 1 1 0 Herpesvirus UL25 family DUF4551 PF15087.6 KLO05040.1 - 3.4 6.4 7.2 4.4 6.0 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ERCC3_RAD25_C PF16203.5 KLO05041.1 - 1.9e-120 400.7 0.0 3.2e-120 399.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KLO05041.1 - 1.5e-36 125.3 0.0 2.5e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO05041.1 - 1.7e-15 57.4 0.0 3.7e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KLO05041.1 - 1.9e-13 50.7 0.2 7.1e-13 48.9 0.2 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KLO05041.1 - 7.3e-10 38.1 0.1 9.4e-10 37.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KLO05041.1 - 6e-05 22.9 0.1 0.00012 22.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KLO05041.1 - 0.00056 19.6 0.2 0.082 12.6 0.1 2.4 2 0 0 2 2 2 1 SWI2/SNF2 ATPase Cas_Csm6 PF09659.10 KLO05041.1 - 0.0034 16.2 0.2 0.096 11.5 0.2 2.4 2 0 0 2 2 2 1 CRISPR-associated protein (Cas_Csm6) RNase_H PF00075.24 KLO05042.1 - 3.1e-28 98.7 0.4 4.6e-28 98.2 0.4 1.1 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.27 KLO05043.1 - 2.8e-07 30.3 0.0 4.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box-like_2 PF13013.6 KLO05043.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain RVT_1 PF00078.27 KLO05044.1 - 5.8e-07 29.3 0.0 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BDV_M PF16520.5 KLO05048.1 - 0.051 13.9 0.2 0.094 13.1 0.2 1.5 1 0 0 1 1 1 0 ssRNA-binding matrix protein of Bornaviridae F-box-like PF12937.7 KLO05049.1 - 0.00012 21.9 0.1 0.00026 20.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05049.1 - 0.0068 16.3 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain HxlR PF01638.17 KLO05049.1 - 0.053 13.4 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 HxlR-like helix-turn-helix Questin_oxidase PF14027.6 KLO05052.1 - 5.8e-91 305.6 0.0 6.8e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like Questin_oxidase PF14027.6 KLO05053.1 - 1.2e-87 294.6 0.0 1.4e-87 294.4 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like DUF5423 PF17461.2 KLO05055.1 - 0.0037 16.2 3.9 0.78 8.5 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5423) FA_hydroxylase PF04116.13 KLO05056.1 - 3.9e-22 79.0 19.7 3.9e-22 79.0 19.7 1.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily KDZ PF18758.1 KLO05057.1 - 8.5e-46 156.4 2.0 1.4e-45 155.7 2.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO05057.1 - 4.6e-25 87.8 0.0 4.6e-25 87.8 0.0 2.2 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO05057.1 - 6e-07 29.6 2.9 9e-07 29.0 0.1 2.3 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases Mit_KHE1 PF10173.9 KLO05057.1 - 0.078 13.1 0.3 0.24 11.4 0.3 1.8 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related CxC3 PF18804.1 KLO05057.1 - 0.31 10.9 0.1 0.31 10.9 0.1 2.1 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases Tet_JBP PF12851.7 KLO05058.1 - 5.3e-05 22.7 0.0 0.00049 19.5 0.0 1.9 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily Helicase_C PF00271.31 KLO05062.1 - 1.1e-15 58.0 0.0 4.9e-15 55.8 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO05062.1 - 3.7e-13 49.6 0.0 5.8e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO05062.1 - 3.5e-07 30.4 0.0 7.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 KLO05062.1 - 0.011 16.5 0.0 0.025 15.3 0.0 1.6 1 0 0 1 1 1 0 RecQ zinc-binding Cauli_VI PF01693.16 KLO05065.1 - 5.6e-07 29.8 0.2 1.2e-06 28.8 0.2 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin KDZ PF18758.1 KLO05066.1 - 2.8e-53 180.8 0.0 4.5e-53 180.1 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO05066.1 - 3e-30 104.5 0.1 3e-30 104.5 0.1 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO05066.1 - 0.032 14.4 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases zf-UBR PF02207.20 KLO05066.1 - 5.6 7.2 12.1 2.9 8.1 0.9 2.9 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) TMEM135_C_rich PF15982.5 KLO05067.1 - 1.6e-09 38.5 0.4 1.2e-08 35.6 0.4 2.1 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 RRF PF01765.19 KLO05068.1 - 0.04 13.9 0.6 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 Ribosome recycling factor Orbi_VP2 PF00898.17 KLO05070.1 - 0.14 9.9 0.0 0.17 9.6 0.0 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 Mtp PF03821.16 KLO05071.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Form_Nir_trans PF01226.17 KLO05075.1 - 9.6e-62 208.4 19.3 1.2e-61 208.1 19.3 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter CP12 PF02672.15 KLO05076.1 - 0.15 12.8 0.0 0.31 11.8 0.0 1.4 1 0 0 1 1 1 0 CP12 domain Pkinase PF00069.25 KLO05077.1 - 2.1e-27 96.2 0.0 5.2e-13 49.0 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05077.1 - 1.5e-11 44.1 0.2 4.7e-05 22.8 0.0 3.7 3 1 0 4 4 4 3 Protein tyrosine kinase APH PF01636.23 KLO05077.1 - 0.013 15.5 0.1 0.09 12.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Lipase_3 PF01764.25 KLO05078.1 - 9.9e-31 106.5 0.1 1.5e-30 105.9 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KLO05078.1 - 0.011 15.7 0.0 0.072 13.1 0.0 2.1 2 0 0 2 2 2 0 Lipase 3 N-terminal region Cutinase PF01083.22 KLO05078.1 - 0.018 15.0 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase Baculo_ME53 PF06061.11 KLO05078.1 - 0.23 10.7 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Baculoviridae ME53 Lipase_3 PF01764.25 KLO05079.1 - 7.6e-31 106.9 0.1 1.4e-30 106.1 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) NIPSNAP PF07978.13 KLO05083.1 - 0.0028 17.8 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 NIPSNAP Lipase_3 PF01764.25 KLO05084.1 - 1.3e-31 109.4 0.1 1.9e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KLO05084.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipase 3 N-terminal region Lipase_3 PF01764.25 KLO05085.1 - 9.9e-31 106.5 0.1 1.5e-30 105.9 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KLO05085.1 - 0.011 15.7 0.0 0.072 13.1 0.0 2.1 2 0 0 2 2 2 0 Lipase 3 N-terminal region Cutinase PF01083.22 KLO05085.1 - 0.018 15.0 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase Baculo_ME53 PF06061.11 KLO05085.1 - 0.23 10.7 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Baculoviridae ME53 Pkinase PF00069.25 KLO05086.1 - 2.1e-27 96.2 0.0 5.2e-13 49.0 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05086.1 - 1.5e-11 44.1 0.2 4.7e-05 22.8 0.0 3.7 3 1 0 4 4 4 3 Protein tyrosine kinase APH PF01636.23 KLO05086.1 - 0.013 15.5 0.1 0.09 12.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family CP12 PF02672.15 KLO05087.1 - 0.15 12.8 0.0 0.31 11.8 0.0 1.4 1 0 0 1 1 1 0 CP12 domain Form_Nir_trans PF01226.17 KLO05088.1 - 9.6e-62 208.4 19.3 1.2e-61 208.1 19.3 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Ras PF00071.22 KLO05097.1 - 3.8e-54 182.7 0.0 4.4e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO05097.1 - 3e-22 79.1 0.0 4.3e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO05097.1 - 9.7e-09 34.9 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KLO05097.1 - 0.0074 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KLO05097.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region F-box-like PF12937.7 KLO05100.1 - 0.00074 19.4 0.9 0.003 17.4 0.9 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05100.1 - 0.0025 17.6 0.0 0.0095 15.8 0.0 2.0 1 0 0 1 1 1 1 F-box domain Nse4_C PF08743.10 KLO05101.1 - 5.3e-29 100.3 0.3 5.3e-29 100.3 0.3 1.8 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KLO05101.1 - 2e-17 63.0 0.5 6.5e-17 61.4 0.5 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Proteasome PF00227.26 KLO05102.1 - 1.4e-53 181.2 0.1 2.5e-53 180.4 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KLO05102.1 - 6.8e-14 51.2 0.1 1.3e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cwf_Cwc_15 PF04889.12 KLO05104.1 - 0.0072 16.1 21.9 0.0088 15.8 21.9 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 KLO05104.1 - 0.17 12.1 24.1 0.26 11.5 24.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC27 PF09507.10 KLO05104.1 - 0.19 11.1 18.4 0.2 11.0 18.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Shugoshin_C PF07557.11 KLO05104.1 - 0.29 11.0 1.7 0.57 10.0 1.7 1.4 1 0 0 1 1 1 0 Shugoshin C terminus NOA36 PF06524.12 KLO05104.1 - 0.37 10.1 20.2 0.48 9.7 20.2 1.1 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.10 KLO05104.1 - 0.66 10.3 11.4 0.74 10.1 11.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 IFT57 PF10498.9 KLO05104.1 - 1.1 8.2 10.0 1.3 7.9 10.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4746 PF15928.5 KLO05104.1 - 1.3 8.4 10.9 1.4 8.3 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Afi1 PF07792.12 KLO05104.1 - 1.8 9.0 8.6 2.2 8.7 8.6 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking BUD22 PF09073.10 KLO05104.1 - 2.1 7.6 23.2 2.3 7.5 23.2 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 KLO05104.1 - 2.5 7.6 23.1 3.1 7.3 23.1 1.1 1 0 0 1 1 1 0 PPP4R2 Astro_capsid_p PF12226.8 KLO05104.1 - 2.5 7.2 14.3 3.1 6.9 14.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DDRGK PF09756.9 KLO05104.1 - 2.6 7.6 14.2 3 7.4 14.2 1.2 1 0 0 1 1 1 0 DDRGK domain DUF2457 PF10446.9 KLO05104.1 - 2.8 7.0 22.5 3.1 6.8 22.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 KLO05104.1 - 2.9 6.0 23.9 2.7 6.1 23.9 1.0 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 KLO05104.1 - 3.2 7.4 14.1 3.7 7.2 14.1 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RPN2_C PF18004.1 KLO05104.1 - 3.7 7.5 12.2 5 7.0 12.2 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CCSAP PF15748.5 KLO05104.1 - 4.2 7.5 13.1 4.6 7.3 13.1 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TRAP_alpha PF03896.16 KLO05104.1 - 7.3 5.7 8.8 9 5.4 8.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NPR3 PF03666.13 KLO05104.1 - 7.5 5.2 11.6 9 5.0 11.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.6 KLO05104.1 - 7.9 6.1 16.8 27 4.4 16.5 1.9 1 1 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 KLO05104.1 - 8.1 4.4 26.6 8.5 4.3 26.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi bZIP_2 PF07716.15 KLO05105.1 - 5e-11 42.5 10.5 5e-11 42.5 10.5 2.9 3 0 0 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.21 KLO05105.1 - 1.9e-10 40.7 15.7 5.9e-10 39.1 7.8 2.6 2 0 0 2 2 2 2 bZIP transcription factor DUF572 PF04502.13 KLO05105.1 - 0.0005 19.8 1.5 0.00052 19.7 1.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Borrelia_P83 PF05262.11 KLO05105.1 - 0.00089 17.9 0.6 0.0011 17.6 0.6 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Fmp27_WPPW PF10359.9 KLO05105.1 - 0.00097 18.1 0.6 0.0011 17.9 0.6 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain TSC22 PF01166.18 KLO05105.1 - 0.038 14.3 4.3 0.058 13.7 0.2 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF724 PF05266.14 KLO05105.1 - 1 9.1 10.0 1.8 8.4 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 KLO05105.1 - 1.3 8.3 9.1 2.1 7.6 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 KLO05105.1 - 1.9 7.0 4.5 2.5 6.6 4.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A bZIP_Maf PF03131.17 KLO05105.1 - 9.9 6.8 24.7 0.066 13.7 13.7 2.7 2 1 1 3 3 3 0 bZIP Maf transcription factor DUF1793 PF08760.11 KLO05108.1 - 7e-36 124.2 0.2 6e-35 121.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KLO05108.1 - 5.9e-35 120.5 0.1 1.2e-34 119.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) Bac_rhamnosid6H PF17389.2 KLO05108.1 - 0.00055 19.3 0.0 0.00098 18.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF5127 PF17168.4 KLO05108.1 - 0.00095 19.0 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) Metallophos PF00149.28 KLO05110.1 - 2.7e-12 47.6 0.2 4e-12 47.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.7 KLO05111.1 - 5.1e-08 32.7 0.1 1.3e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05111.1 - 0.015 15.2 2.9 3 7.8 0.4 3.5 3 0 0 3 3 3 0 F-box domain KDZ PF18758.1 KLO05116.1 - 5.5e-38 130.8 0.0 9.7e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DAO PF01266.24 KLO05118.1 - 3.3e-56 191.4 0.6 3.9e-56 191.2 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO05118.1 - 0.00015 22.0 0.3 0.00051 20.2 0.2 1.9 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO05118.1 - 0.0011 18.2 0.3 0.073 12.3 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO05118.1 - 0.0023 17.2 0.5 0.004 16.4 0.5 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KLO05118.1 - 0.026 15.1 0.4 0.053 14.1 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KLO05118.1 - 0.034 12.9 0.1 0.051 12.4 0.1 1.2 1 0 0 1 1 1 0 MCRA family Trp_halogenase PF04820.14 KLO05118.1 - 0.059 12.2 0.1 0.071 12.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 KLO05118.1 - 0.062 12.4 0.1 4.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KLO05118.1 - 0.09 11.8 1.0 0.38 9.8 0.4 1.9 2 0 0 2 2 2 0 FAD binding domain Dimer_Tnp_hAT PF05699.14 KLO05129.1 - 4.1e-06 26.5 0.0 8.5e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region CHASE PF03924.13 KLO05129.1 - 0.079 12.9 0.1 0.11 12.4 0.1 1.3 1 1 0 1 1 1 0 CHASE domain AAA_22 PF13401.6 KLO05131.1 - 2.7e-08 34.2 0.0 0.00046 20.5 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KLO05131.1 - 2.7e-08 34.4 0.0 0.00065 20.1 0.0 3.1 2 0 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.22 KLO05131.1 - 1.3e-06 27.8 0.0 0.003 16.8 0.0 3.0 2 0 0 2 2 2 2 NB-ARC domain AAA PF00004.29 KLO05131.1 - 1.8e-06 28.4 0.1 0.0031 17.9 0.0 3.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KLO05131.1 - 3.5e-06 27.0 2.6 0.0051 16.7 0.4 3.6 2 1 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 KLO05131.1 - 3.8e-06 27.5 0.0 0.2 12.2 0.0 3.7 3 1 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 KLO05131.1 - 4.6e-06 26.0 0.0 0.016 14.5 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 KLO05131.1 - 2e-05 24.7 0.0 0.16 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KLO05131.1 - 6.4e-05 23.3 0.0 0.29 11.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ResIII PF04851.15 KLO05131.1 - 0.00015 21.8 0.0 0.039 13.9 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KLO05131.1 - 0.00017 21.2 0.2 1 8.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KLO05131.1 - 0.00021 20.6 0.1 0.2 10.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Ploopntkinase3 PF18751.1 KLO05131.1 - 0.0003 20.8 0.0 0.35 10.8 0.0 2.5 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KLO05131.1 - 0.00041 20.9 0.4 0.67 10.5 0.1 3.4 3 1 0 3 3 2 1 ABC transporter Parvo_NS1 PF01057.17 KLO05131.1 - 0.00047 19.3 0.1 0.15 11.1 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 APS_kinase PF01583.20 KLO05131.1 - 0.00052 19.9 1.1 2 8.3 0.0 3.4 3 0 0 3 3 3 2 Adenylylsulphate kinase AAA_24 PF13479.6 KLO05131.1 - 0.00086 19.1 0.4 0.69 9.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain PPV_E1_C PF00519.17 KLO05131.1 - 0.0011 18.0 0.0 1.1 8.0 0.0 2.3 2 0 0 2 2 2 2 Papillomavirus helicase AAA_14 PF13173.6 KLO05131.1 - 0.0014 18.7 0.0 8.8 6.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_PrkA PF08298.11 KLO05131.1 - 0.002 17.1 0.0 0.093 11.6 0.0 2.4 2 0 0 2 2 2 1 PrkA AAA domain TIP49 PF06068.13 KLO05131.1 - 0.003 16.8 0.1 0.085 12.0 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase_2 PF01637.18 KLO05131.1 - 0.0039 17.2 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KLO05131.1 - 0.0043 17.4 0.5 0.23 11.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KLO05131.1 - 0.0049 17.3 0.7 3.5 8.1 0.3 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KLO05131.1 - 0.0068 16.7 0.0 4.6 7.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KLO05131.1 - 0.0079 15.6 0.0 0.73 9.2 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 KLO05131.1 - 0.0081 15.9 0.1 4.7 6.9 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KLO05131.1 - 0.013 15.6 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 KLO05131.1 - 0.013 15.5 0.1 9 6.4 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KLO05131.1 - 0.014 15.1 0.1 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KLO05131.1 - 0.017 15.1 0.0 4.8 7.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KLO05131.1 - 0.019 14.4 0.0 6.1 6.2 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KLO05131.1 - 0.024 13.8 0.0 7.5 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KLO05131.1 - 0.024 14.6 0.0 3.1 7.7 0.0 2.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 KLO05131.1 - 0.025 14.1 0.0 0.97 8.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ADK PF00406.22 KLO05131.1 - 0.04 14.0 0.2 8.3 6.5 0.0 2.8 2 0 0 2 2 2 0 Adenylate kinase Viral_helicase1 PF01443.18 KLO05131.1 - 0.04 13.7 0.0 5 6.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF4081 PF13312.6 KLO05132.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4081) OrfB_Zn_ribbon PF07282.11 KLO05132.1 - 0.55 10.2 3.2 6.9 6.7 4.5 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain WD40 PF00400.32 KLO05135.1 - 3.8e-58 192.1 26.8 3.6e-09 37.1 0.2 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO05135.1 - 9.9e-23 80.3 0.2 0.00095 19.4 0.0 7.9 2 1 6 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO05135.1 - 2.8e-11 43.0 1.6 0.2 10.6 0.0 6.6 1 1 5 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KLO05135.1 - 7.7e-06 25.7 7.1 4.2 7.4 0.0 6.0 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KLO05135.1 - 0.00058 19.3 6.1 0.66 9.3 0.0 5.3 2 2 2 6 6 6 1 Neuroblastoma-amplified sequence, N terminal NACHT PF05729.12 KLO05135.1 - 0.0012 18.8 0.1 0.0035 17.3 0.1 1.7 1 1 0 1 1 1 1 NACHT domain WD40_like PF17005.5 KLO05135.1 - 0.0016 17.9 0.0 9.9 5.4 0.0 3.6 4 0 0 4 4 4 0 WD40-like domain Zeta_toxin PF06414.12 KLO05135.1 - 0.0023 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 KLO05135.1 - 0.0035 17.8 0.0 0.0087 16.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO05135.1 - 0.007 16.6 0.0 0.028 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KLO05135.1 - 0.0093 16.1 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO05135.1 - 0.012 16.0 0.0 0.036 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Nucleoporin_N PF08801.11 KLO05135.1 - 0.014 14.2 0.7 0.068 11.9 0.3 2.1 1 1 2 3 3 3 0 Nup133 N terminal like AAA_18 PF13238.6 KLO05135.1 - 0.021 15.4 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Nup160 PF11715.8 KLO05135.1 - 0.026 13.2 0.1 3.7 6.1 0.0 3.4 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Glyoxal_oxid_N PF07250.11 KLO05135.1 - 0.079 12.1 0.1 2.2 7.4 0.0 2.4 1 1 0 2 2 2 0 Glyoxal oxidase N-terminus NB-ARC PF00931.22 KLO05135.1 - 0.086 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 KLO05135.1 - 0.088 13.0 0.0 30 4.9 0.0 3.8 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 KLO05135.1 - 0.098 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Frtz PF11768.8 KLO05135.1 - 0.13 10.5 0.0 2.7 6.2 0.0 2.3 1 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz KAP_NTPase PF07693.14 KLO05135.1 - 0.16 11.2 0.0 0.34 10.1 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain CBP_BcsQ PF06564.12 KLO05136.1 - 0.059 12.8 0.2 0.072 12.6 0.2 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ SPRY PF00622.28 KLO05137.1 - 9.7e-26 90.2 0.2 1.8e-25 89.4 0.2 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 KLO05137.1 - 1.4e-22 80.1 0.0 2.1e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KLO05137.1 - 1e-05 25.3 0.1 3.2e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 LisH ABC_tran PF00005.27 KLO05138.1 - 3.6e-46 157.1 0.0 1.8e-23 83.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KLO05138.1 - 1.9e-23 82.3 3.8 1.9e-23 82.3 3.8 2.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KLO05138.1 - 3.1e-14 53.5 8.8 0.0024 17.8 0.0 4.4 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KLO05138.1 - 9.6e-08 32.1 0.0 0.0078 16.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KLO05138.1 - 3.4e-07 29.9 0.1 0.12 11.8 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KLO05138.1 - 8.5e-07 28.6 0.6 0.028 14.2 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KLO05138.1 - 6.2e-06 26.2 0.7 0.061 13.2 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KLO05138.1 - 1.2e-05 25.8 1.3 0.36 11.2 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain MeaB PF03308.16 KLO05138.1 - 2.6e-05 23.3 0.5 0.011 14.8 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KLO05138.1 - 2.7e-05 24.5 2.2 0.36 11.1 0.2 3.8 3 2 0 3 3 3 2 AAA domain NACHT PF05729.12 KLO05138.1 - 4.1e-05 23.5 0.1 0.25 11.2 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_18 PF13238.6 KLO05138.1 - 5.5e-05 23.7 0.5 0.56 10.7 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.6 KLO05138.1 - 0.0002 21.6 0.5 0.23 11.7 0.1 3.0 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KLO05138.1 - 0.0014 18.8 0.6 1 9.5 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.6 KLO05138.1 - 0.0016 18.2 0.0 2.7 7.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KLO05138.1 - 0.002 18.7 14.7 0.18 12.3 0.0 4.5 4 1 0 4 4 3 2 AAA domain AAA_30 PF13604.6 KLO05138.1 - 0.0026 17.5 0.0 0.68 9.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KLO05138.1 - 0.0028 17.4 8.6 0.51 10.0 0.3 4.2 4 0 0 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.22 KLO05138.1 - 0.0069 16.8 0.0 3.2 8.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 KLO05138.1 - 0.0085 16.0 0.1 2.6 7.9 0.1 2.8 2 0 0 2 2 2 1 NTPase AAA PF00004.29 KLO05138.1 - 0.012 16.1 0.0 5.9 7.3 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KLO05138.1 - 0.017 14.3 0.3 4.3 6.4 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain Roc PF08477.13 KLO05138.1 - 0.018 15.3 0.1 6 7.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KLO05138.1 - 0.021 14.9 0.7 11 6.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KLO05138.1 - 0.022 14.8 2.8 0.22 11.6 0.1 3.1 3 1 0 3 3 3 0 Dynamin family DUF815 PF05673.13 KLO05138.1 - 0.03 13.5 0.1 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 KLO05138.1 - 0.033 13.8 0.2 6.1 6.4 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 KLO05138.1 - 0.036 13.9 1.4 4.7 7.0 0.0 2.9 3 0 0 3 3 3 0 Deoxynucleoside kinase DUF87 PF01935.17 KLO05138.1 - 0.038 14.1 0.1 0.038 14.1 0.1 3.5 4 1 0 4 4 3 0 Helicase HerA, central domain AAA_25 PF13481.6 KLO05138.1 - 0.048 13.2 0.1 22 4.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain FeoB_N PF02421.18 KLO05138.1 - 0.051 13.1 0.1 1.5 8.3 0.1 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 KLO05138.1 - 0.066 12.7 0.1 13 5.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KLO05138.1 - 0.094 12.4 0.0 19 4.9 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 KLO05138.1 - 0.1 12.6 0.2 6.5 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 KLO05138.1 - 0.1 12.5 0.0 5 7.0 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 SbcCD_C PF13558.6 KLO05138.1 - 0.13 12.5 0.3 5.2 7.4 0.1 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 KLO05138.1 - 0.15 11.4 2.1 0.18 11.1 0.2 2.1 3 0 0 3 3 2 0 Zeta toxin Lipase_3 PF01764.25 KLO05140.1 - 1.1e-14 54.4 0.0 3.7e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KLO05140.1 - 0.0028 18.3 1.3 0.15 12.7 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO05140.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF3328 PF11807.8 KLO05141.1 - 5.2e-11 42.7 0.1 6.2e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) F-box-like PF12937.7 KLO05141.1 - 0.019 14.9 0.3 0.064 13.2 0.3 1.9 1 1 0 1 1 1 0 F-box-like TbpB_A PF17484.2 KLO05145.1 - 0.065 14.0 0.0 0.19 12.5 0.0 1.7 1 0 0 1 1 1 0 N-Lobe handle Tf-binding protein B TT_ORF2 PF02957.15 KLO05146.1 - 0.12 13.2 0.1 0.12 13.2 0.1 5.3 6 0 0 6 6 6 0 TT viral ORF2 TOH_N PF12549.8 KLO05147.1 - 0.005 16.6 0.4 0.026 14.4 0.4 2.3 1 0 0 1 1 1 1 Tyrosine hydroxylase N terminal DUF1899 PF08953.11 KLO05151.1 - 7.9e-30 102.5 0.0 1.6e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 KLO05151.1 - 2e-17 63.2 0.5 6.9e-05 23.5 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_4 PF16300.5 KLO05151.1 - 2.8e-17 62.3 0.2 6.5e-17 61.1 0.2 1.7 1 0 0 1 1 1 1 Type of WD40 repeat ANAPC4_WD40 PF12894.7 KLO05151.1 - 1.2e-05 25.5 0.0 0.14 12.5 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DivIC PF04977.15 KLO05151.1 - 0.026 14.3 2.0 0.044 13.6 2.0 1.3 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 KLO05151.1 - 0.037 14.5 4.4 0.053 14.0 4.4 1.2 1 0 0 1 1 1 0 Cell division protein ZapB SHE3 PF17078.5 KLO05151.1 - 0.041 13.6 1.7 0.056 13.1 1.7 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Syntaxin-6_N PF09177.11 KLO05151.1 - 0.048 14.2 0.4 0.087 13.4 0.4 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal EBP50_C PF09007.11 KLO05151.1 - 4.5 8.3 7.8 8.6 7.4 7.8 1.4 1 0 0 1 1 1 0 EBP50, C-terminal DUF2576 PF10845.8 KLO05152.1 - 2 8.1 5.3 3.1 7.5 0.6 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF2576) CTD_bind PF04818.13 KLO05156.1 - 0.011 16.5 0.0 0.059 14.2 0.0 2.1 1 1 1 2 2 2 0 RNA polymerase II-binding domain. OPT PF03169.15 KLO05160.1 - 2.8e-08 32.9 0.5 2.8e-08 32.9 0.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1918 PF08940.11 KLO05160.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Mga PF05043.13 KLO05162.1 - 0.016 15.7 0.1 0.039 14.5 0.1 1.6 1 0 0 1 1 1 0 Mga helix-turn-helix domain DNA_pol_A PF00476.20 KLO05162.1 - 0.092 11.8 1.2 2.4 7.1 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase family A STAG PF08514.11 KLO05162.1 - 0.16 11.9 2.1 0.18 11.7 0.7 1.8 2 0 0 2 2 2 0 STAG domain Fungal_trans PF04082.18 KLO05163.1 - 9e-10 38.0 0.1 1.4e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO05163.1 - 6.6e-08 32.6 7.7 1.1e-07 31.8 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pterin_4a PF01329.19 KLO05163.1 - 0.11 12.7 0.3 0.41 10.9 0.0 2.1 3 0 0 3 3 3 0 Pterin 4 alpha carbinolamine dehydratase PAP1 PF08601.10 KLO05163.1 - 2.9 7.5 6.7 15 5.2 0.1 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 Tom22 PF04281.13 KLO05164.1 - 7e-38 129.5 2.0 8.3e-38 129.3 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Glyco_hydro_35 PF01301.19 KLO05165.1 - 6.7e-84 282.2 0.3 1.1e-83 281.5 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KLO05165.1 - 4.1e-57 191.7 9.2 5.9e-32 110.6 0.2 3.7 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KLO05165.1 - 2.2e-33 115.6 2.3 4.1e-33 114.7 2.3 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KLO05165.1 - 4.8e-22 77.3 2.9 1.2e-21 76.0 0.2 2.8 3 0 0 3 3 3 1 Beta-galactosidase, domain 3 YCF90 PF17088.5 KLO05165.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family ABATE PF07336.11 KLO05166.1 - 0.047 14.4 0.0 7.4 7.3 0.1 2.1 2 0 0 2 2 2 0 Putative stress-induced transcription regulator APH PF01636.23 KLO05167.1 - 0.00058 19.9 0.0 0.0007 19.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family TEA PF01285.18 KLO05167.1 - 0.079 13.1 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 TEA/ATTS domain FdsD PF11390.8 KLO05167.1 - 0.17 12.2 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD Fructosamin_kin PF03881.14 KLO05167.1 - 0.19 10.9 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase APH PF01636.23 KLO05168.1 - 5.4e-05 23.2 0.0 9.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Retro_M PF02813.14 KLO05168.1 - 0.13 12.6 0.0 0.21 12.0 0.0 1.4 1 1 0 1 1 1 0 Retroviral M domain adh_short_C2 PF13561.6 KLO05169.1 - 4.1e-24 85.4 0.1 5.8e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO05169.1 - 8.9e-18 64.5 0.0 1.1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase FtsK_alpha PF17854.1 KLO05169.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 FtsK alpha domain KR PF08659.10 KLO05169.1 - 0.074 13.0 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 KR domain 3HCDH_N PF02737.18 KLO05169.1 - 0.085 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KLO05169.1 - 0.24 12.0 1.3 0.44 11.1 1.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SDA1 PF05285.12 KLO05174.1 - 0.039 13.4 17.9 0.051 13.0 17.9 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KLO05174.1 - 0.11 10.6 26.7 0.18 9.9 26.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 KLO05174.1 - 0.15 11.4 17.7 0.23 10.7 17.7 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KLO05174.1 - 0.25 9.5 23.2 0.34 9.1 23.2 1.1 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 KLO05174.1 - 0.86 7.3 6.0 5.6 4.6 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit LAP1C PF05609.12 KLO05174.1 - 1.8 7.6 10.6 2.5 7.1 10.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RXT2_N PF08595.11 KLO05174.1 - 3.3 7.7 13.0 6.1 6.9 13.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2784 PF10861.8 KLO05175.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) Ribosomal_L4 PF00573.22 KLO05177.1 - 4e-42 144.1 1.5 4e-42 144.1 1.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KLO05177.1 - 2.7e-29 101.0 3.2 7.1e-29 99.7 3.2 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain DUF1543 PF07566.12 KLO05177.1 - 0.046 13.5 0.4 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) DUF1768 PF08719.11 KLO05178.1 - 1.3e-29 103.5 0.0 1.7e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF4616 PF15394.6 KLO05178.1 - 0.033 13.2 0.5 0.061 12.3 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) Fer4_11 PF13247.6 KLO05179.1 - 1.8 8.7 16.1 1.5 9.0 1.7 3.5 2 2 1 3 3 3 0 4Fe-4S dicluster domain PLATZ PF04640.14 KLO05180.1 - 0.028 15.0 16.7 0.67 10.6 0.3 3.4 2 1 1 3 3 3 0 PLATZ transcription factor DUF1768 PF08719.11 KLO05181.1 - 4.8e-29 101.7 0.0 5.9e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PARP PF00644.20 KLO05182.1 - 2.8e-14 53.2 3.1 2.5e-09 37.0 0.2 3.1 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain zf-FCS PF06467.14 KLO05182.1 - 4.6 7.3 9.2 1.6 8.7 2.3 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif RPAP2_Rtr1 PF04181.13 KLO05183.1 - 0.11 12.8 0.2 0.11 12.8 0.2 3.8 3 1 1 4 4 4 0 Rtr1/RPAP2 family zf-FCS PF06467.14 KLO05183.1 - 0.15 12.1 0.4 0.15 12.1 0.4 4.4 4 1 1 5 5 5 0 MYM-type Zinc finger with FCS sequence motif CstA_5TM PF13722.6 KLO05185.1 - 0.072 13.5 8.0 0.13 12.7 7.7 1.8 1 1 0 1 1 1 0 5TM C-terminal transporter carbon starvation CstA ATG22 PF11700.8 KLO05189.1 - 4.3e-116 388.4 16.2 4.9e-116 388.2 16.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KLO05189.1 - 1.1e-12 47.5 27.5 4.1e-09 35.8 9.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SHOCT PF09851.9 KLO05189.1 - 0.0038 16.9 3.3 0.0063 16.2 3.3 1.3 1 0 0 1 1 1 1 Short C-terminal domain GvpG PF05120.12 KLO05189.1 - 0.1 12.6 0.2 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 Gas vesicle protein G Bacteriocin_II PF01721.18 KLO05189.1 - 0.1 12.7 0.3 0.3 11.2 0.3 1.8 1 0 0 1 1 1 0 Class II bacteriocin DUF2721 PF11026.8 KLO05189.1 - 0.72 9.8 0.0 0.72 9.8 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2721) Sucrose_synth PF00862.19 KLO05190.1 - 0.15 10.3 0.0 0.15 10.3 0.0 1.0 1 0 0 1 1 1 0 Sucrose synthase F-box-like PF12937.7 KLO05191.1 - 9.3e-07 28.7 0.4 4e-06 26.6 0.0 2.4 2 1 0 2 2 2 1 F-box-like TPR_19 PF14559.6 KLO05191.1 - 0.19 12.3 0.1 0.44 11.1 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box PF00646.33 KLO05191.1 - 0.3 11.0 3.7 18 5.3 0.0 3.6 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO05192.1 - 1.1e-06 28.4 0.9 5.4e-06 26.2 0.5 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO05192.1 - 0.027 14.3 1.9 0.41 10.6 1.9 3.0 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO05193.1 - 8.7e-09 35.1 0.2 2e-08 34.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO05193.1 - 0.27 11.7 4.4 17 6.0 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO05194.1 - 2e-08 34.0 0.4 6.9e-08 32.3 0.4 2.0 1 0 0 1 1 1 1 F-box-like DUF4648 PF15505.6 KLO05200.1 - 0.78 10.7 0.1 0.78 10.7 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4648) Inhibitor_I36 PF03995.13 KLO05202.1 - 0.056 13.4 0.4 0.13 12.2 0.4 1.6 1 0 0 1 1 1 0 Peptidase inhibitor family I36 GMC_oxred_C PF05199.13 KLO05207.1 - 1.1e-12 48.7 0.1 3.1e-12 47.2 0.1 1.8 1 1 0 1 1 1 1 GMC oxidoreductase NAD_Gly3P_dh_N PF01210.23 KLO05207.1 - 0.0021 18.0 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KLO05207.1 - 0.0089 16.6 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 KLO05207.1 - 0.011 15.0 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KLO05207.1 - 0.022 14.0 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GMC_oxred_N PF00732.19 KLO05207.1 - 0.034 13.5 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 GMC oxidoreductase 3HCDH_N PF02737.18 KLO05207.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KLO05207.1 - 0.12 12.6 0.0 1.2 9.4 0.0 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain AUDH_Cupin PF18637.1 KLO05208.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain GMC_oxred_C PF05199.13 KLO05211.1 - 1.8e-14 54.5 0.0 5e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KLO05211.1 - 0.0098 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase DUF3173 PF11372.8 KLO05211.1 - 0.062 13.2 0.1 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) HTH_51 PF18558.1 KLO05213.1 - 0.026 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Alpha_kinase PF02816.18 KLO05214.1 - 1.7e-05 25.1 0.0 2.3e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Alpha-kinase family PAP2_3 PF14378.6 KLO05216.1 - 2.7e-22 79.4 21.3 2.7e-22 79.4 21.3 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KLO05216.1 - 4.1e-09 36.3 9.0 4.1e-09 36.3 9.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KLO05216.1 - 0.00063 20.2 4.2 0.00063 20.2 4.2 2.8 2 1 1 3 3 3 1 PAP2 superfamily C-terminal DnaJ-X PF14308.6 KLO05217.1 - 6.7e-53 179.3 0.4 1.5e-52 178.1 0.4 1.5 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 KLO05217.1 - 7.2e-26 90.1 2.8 1.7e-25 88.9 2.8 1.7 1 0 0 1 1 1 1 DnaJ domain Tom5 PF10642.9 KLO05217.1 - 5.8 7.0 5.2 10 6.3 0.9 2.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Transferrin PF00405.17 KLO05220.1 - 0.07 12.3 0.2 0.091 11.9 0.2 1.1 1 0 0 1 1 1 0 Transferrin Retrotran_gag_2 PF14223.6 KLO05222.1 - 9e-12 44.8 0.0 1.1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KLO05222.1 - 2.7e-06 27.1 0.0 1.5e-05 24.7 0.1 2.2 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KLO05222.1 - 0.016 14.8 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) TFIIA PF03153.13 KLO05228.1 - 0.0023 18.0 1.5 0.0023 18.0 1.5 2.9 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF641 PF04859.12 KLO05228.1 - 0.25 11.7 9.1 1.6 9.1 0.0 3.1 2 1 0 3 3 3 0 Plant protein of unknown function (DUF641) DNA_pol_phi PF04931.13 KLO05228.1 - 1.6 6.7 11.5 2.8 5.9 11.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi HMMR_N PF15905.5 KLO05228.1 - 2 7.8 18.9 0.54 9.7 4.7 2.1 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ADIP PF11559.8 KLO05228.1 - 2.5 8.2 14.1 0.75 9.9 3.9 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding NOA36 PF06524.12 KLO05228.1 - 2.9 7.1 13.6 5.2 6.3 13.6 1.3 1 0 0 1 1 1 0 NOA36 protein Spc7 PF08317.11 KLO05228.1 - 2.9 6.7 21.4 0.12 11.3 5.6 2.9 1 1 1 3 3 3 0 Spc7 kinetochore protein SlyX PF04102.12 KLO05228.1 - 3.4 8.4 14.6 77 4.0 1.0 4.8 2 1 1 3 3 3 0 SlyX Fez1 PF06818.15 KLO05228.1 - 6.1 7.2 15.1 3.9 7.9 6.3 2.4 1 1 1 2 2 2 0 Fez1 IL2 PF00715.17 KLO05228.1 - 7 6.6 5.9 2.5 8.0 1.9 2.2 1 1 1 2 2 2 0 Interleukin 2 AT_hook PF02178.19 KLO05229.1 - 0.017 14.9 3.3 0.017 14.9 3.3 3.1 3 0 0 3 3 3 0 AT hook motif PBP1_TM PF14812.6 KLO05229.1 - 7.4 7.0 13.5 5.3 7.5 0.5 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_3 PF13358.6 KLO05230.1 - 4.1e-09 36.3 0.0 4.2e-09 36.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO05231.1 - 8.3e-07 28.9 0.0 1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4329 PF14220.6 KLO05233.1 - 0.0046 17.0 0.0 0.0065 16.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4329) BTB PF00651.31 KLO05235.1 - 3.4e-06 27.3 0.1 1e-05 25.7 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain WD40 PF00400.32 KLO05237.1 - 2.8e-125 404.5 36.0 5.4e-09 36.5 0.0 15.9 15 0 0 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO05237.1 - 9.6e-47 157.2 2.0 0.0007 19.8 0.0 14.2 1 1 12 14 14 14 11 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO05237.1 - 4.8e-22 78.8 0.0 0.00038 20.4 0.0 6.0 2 2 4 6 6 6 5 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KLO05237.1 - 5.6e-18 64.4 4.6 7.6 6.6 0.1 13.0 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KLO05237.1 - 8.1e-14 51.3 0.6 1 8.2 0.0 10.6 2 2 10 13 13 13 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KLO05237.1 - 1e-09 37.6 4.0 5 5.6 0.1 9.9 5 3 7 12 12 12 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KLO05237.1 - 3.2e-08 33.3 0.2 6.4 6.0 0.0 8.4 7 2 1 9 9 9 0 WD40-like domain PQQ_2 PF13360.6 KLO05237.1 - 1.7e-06 27.8 5.6 0.032 13.8 1.8 5.0 2 2 1 3 3 3 2 PQQ-like domain Ret2_MD PF18528.1 KLO05237.1 - 2e-06 28.1 0.0 14 6.2 0.0 7.7 7 2 3 10 10 9 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Cytochrom_D1 PF02239.16 KLO05237.1 - 3.5e-06 25.8 4.0 0.027 13.0 0.6 4.5 2 1 1 4 4 4 2 Cytochrome D1 heme domain Nbas_N PF15492.6 KLO05237.1 - 8.2e-06 25.4 2.7 1.8 7.8 0.0 6.1 1 1 4 6 6 6 2 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.9 KLO05237.1 - 3.3e-05 23.5 6.6 1.7e+02 2.0 0.0 10.5 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature ATPase_2 PF01637.18 KLO05237.1 - 0.00011 22.2 0.1 0.029 14.3 0.0 3.3 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea nos_propeller PF18764.1 KLO05237.1 - 0.0003 20.6 7.7 7.1 6.6 0.0 7.2 7 0 0 7 7 6 0 Nitrous oxide reductase propeller repeat DsbC_N PF10411.9 KLO05237.1 - 0.001 18.5 4.5 1.2e+02 2.3 0.0 7.6 8 0 0 8 8 8 0 Disulfide bond isomerase protein N-terminus NACHT PF05729.12 KLO05237.1 - 0.0017 18.3 0.0 0.005 16.8 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO05237.1 - 0.002 18.5 0.0 0.02 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF5570 PF17731.1 KLO05237.1 - 0.0037 17.4 8.0 23 5.1 0.0 6.6 5 3 2 7 7 7 0 Family of unknown function (DUF5570) AAA_24 PF13479.6 KLO05237.1 - 0.0042 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain DCX PF03607.17 KLO05237.1 - 0.014 15.5 0.2 94 3.2 0.0 5.7 6 0 0 6 6 5 0 Doublecortin DUF5046 PF16465.5 KLO05237.1 - 0.017 14.6 0.7 1.9 7.9 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF5046) PQQ PF01011.21 KLO05237.1 - 0.033 14.1 0.1 58 3.9 0.0 5.2 6 0 0 6 6 5 0 PQQ enzyme repeat RNA_helicase PF00910.22 KLO05237.1 - 0.049 14.0 0.0 0.22 11.9 0.0 2.2 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KLO05237.1 - 0.097 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KLO05237.1 - 0.17 12.0 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KLO05237.1 - 0.17 12.1 0.0 3.7 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KLO05237.1 - 0.18 11.7 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase FCP1_C PF09309.10 KLO05237.1 - 0.25 11.2 0.1 1.7 8.5 0.0 2.4 4 0 0 4 4 2 0 FCP1, C-terminal DNA_pol_A_exo1 PF01612.20 KLO05240.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease zf-C2H2_4 PF13894.6 KLO05241.1 - 0.035 15.0 0.5 0.082 13.8 0.1 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 KLO05241.1 - 0.045 14.1 0.1 0.084 13.2 0.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding UBZ_FAAP20 PF15750.5 KLO05241.1 - 0.087 12.8 0.3 0.19 11.7 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger Cucumo_coat PF00760.18 KLO05241.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Cucumovirus coat protein PHD PF00628.29 KLO05242.1 - 0.0011 18.8 2.6 0.0011 18.8 2.6 2.1 2 0 0 2 2 2 1 PHD-finger Taq-exonuc PF09281.10 KLO05242.1 - 0.0082 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Taq polymerase, exonuclease Prok-RING_1 PF14446.6 KLO05242.1 - 0.018 14.9 6.5 0.038 13.9 1.2 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Phage_integrase PF00589.22 KLO05243.1 - 4e-05 23.5 0.0 0.00075 19.3 0.0 2.6 1 1 0 1 1 1 1 Phage integrase family XPG_I PF00867.18 KLO05244.1 - 2.2e-13 50.3 0.0 4.5e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region zf-MYND PF01753.18 KLO05245.1 - 1.5e-07 31.4 15.7 1.5e-07 31.4 15.7 2.1 2 0 0 2 2 2 1 MYND finger zinc-ribbons_6 PF07191.12 KLO05245.1 - 0.014 15.4 2.2 0.032 14.2 2.2 1.5 1 0 0 1 1 1 0 zinc-ribbons fn3_2 PF16893.5 KLO05246.1 - 3.9e-39 132.7 0.5 8.6e-39 131.6 0.5 1.6 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KLO05246.1 - 6.4e-26 90.0 0.1 1.1e-25 89.3 0.1 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 KLO05246.1 - 8.6e-08 32.5 0.0 1.4e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KLO05246.1 - 4.1e-05 23.4 0.0 8.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KLO05246.1 - 0.00075 19.9 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 KLO05246.1 - 0.0024 18.1 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 KLO05246.1 - 0.0031 17.8 1.1 0.023 15.1 1.1 2.4 1 1 0 1 1 1 1 Fibronectin type III domain DEAD PF00270.29 KLO05248.1 - 1.5e-06 28.1 0.0 1.5e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO05248.1 - 0.053 13.5 0.0 0.053 13.5 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Herpes_ori_bp PF02399.15 KLO05248.1 - 0.13 10.3 0.1 0.13 10.3 0.1 1.0 1 0 0 1 1 1 0 Origin of replication binding protein Cauli_VI PF01693.16 KLO05250.1 - 3.6e-05 24.0 5.2 5.8e-05 23.3 5.2 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Thioredoxin_13 PF18401.1 KLO05250.1 - 0.095 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DUF3660 PF12398.8 KLO05251.1 - 0.0073 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Receptor serine/threonine kinase NUC130_3NT PF08158.12 KLO05252.1 - 0.0035 17.6 0.0 0.33 11.3 0.0 3.1 3 0 0 3 3 3 1 NUC130/3NT domain COG6 PF06419.11 KLO05255.1 - 0.012 13.8 0.0 0.016 13.5 0.0 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Tht1 PF04163.12 KLO05256.1 - 0.0039 16.0 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein TACC_C PF05010.14 KLO05256.1 - 0.0041 16.9 5.5 0.0078 16.0 0.3 2.7 2 2 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal NPV_P10 PF05531.12 KLO05256.1 - 0.021 15.3 1.7 9.7 6.7 0.1 3.7 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 KLO05256.1 - 0.32 10.8 5.1 0.13 12.0 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF724) DUF3829 PF12889.7 KLO05256.1 - 0.94 8.9 4.1 0.47 9.9 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3829) Sen15 PF09631.10 KLO05258.1 - 2.8e-20 72.5 0.0 3.6e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein Sen15 PF09631.10 KLO05261.1 - 5.7e-18 65.1 0.0 8.2e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein PAP2_3 PF14378.6 KLO05262.1 - 3.3 7.3 10.9 0.41 10.3 4.5 2.2 1 1 0 2 2 2 0 PAP2 superfamily Plavaka PF18759.1 KLO05267.1 - 5.5e-58 196.7 0.0 1.3e-43 149.4 0.0 2.2 1 1 1 2 2 2 2 Plavaka transposase PLAT PF01477.23 KLO05267.1 - 0.0035 17.9 0.1 3.6 8.2 0.0 2.5 2 0 0 2 2 2 2 PLAT/LH2 domain TFIIA PF03153.13 KLO05268.1 - 0.013 15.6 10.9 0.017 15.2 10.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRN9 PF10680.9 KLO05268.1 - 0.13 12.6 0.7 0.37 11.1 0.7 1.8 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Baculo_E56 PF04639.12 KLO05269.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope ATP-synt_DE_N PF02823.16 KLO05274.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF493 PF04359.14 KLO05278.1 - 0.13 12.8 0.0 0.48 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF493) Nop53 PF07767.11 KLO05282.1 - 0.18 11.2 14.4 0.24 10.8 14.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PSDC PF12588.8 KLO05283.1 - 1.1e-29 103.2 0.0 1.9e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KLO05283.1 - 2.1e-29 102.5 0.0 3.1e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M20 PF01546.28 KLO05284.1 - 6.9e-29 101.0 0.0 8.6e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KLO05284.1 - 4.1e-08 33.1 0.0 6.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KLO05284.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 WD40 PF00400.32 KLO05285.1 - 1.7e-12 47.6 28.8 0.00075 20.3 2.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Arginase PF00491.21 KLO05286.1 - 5e-88 295.2 0.1 6.6e-88 294.8 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KLO05286.1 - 0.13 12.5 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain RicinB_lectin_2 PF14200.6 KLO05287.1 - 5.1e-05 23.9 0.0 0.0007 20.3 0.0 2.3 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KLO05287.1 - 0.082 13.2 0.0 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Pkinase_fungal PF17667.1 KLO05288.1 - 1.1e-74 251.7 0.0 1.1e-74 251.7 0.0 1.8 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 KLO05288.1 - 5.6e-05 22.6 0.0 0.083 12.2 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05288.1 - 0.0039 16.5 0.5 0.017 14.4 0.6 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KLO05288.1 - 0.021 14.2 1.4 0.99 8.7 0.1 3.1 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF465 PF04325.13 KLO05288.1 - 0.044 13.8 0.1 0.14 12.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF465) RR_TM4-6 PF06459.12 KLO05288.1 - 6.3 6.5 12.4 0.85 9.4 0.8 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CCDC106 PF15794.5 KLO05288.1 - 9 5.9 12.1 0.17 11.6 4.5 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Plavaka PF18759.1 KLO05295.1 - 6e-06 25.7 0.0 9.7e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Transposase_21 PF02992.14 KLO05295.1 - 7.5e-05 22.1 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 KLO05295.1 - 0.00025 20.7 0.1 0.0005 19.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Spt5-NGN PF03439.13 KLO05297.1 - 2.5e-05 24.1 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF3912 PF13051.6 KLO05297.1 - 0.057 13.7 0.3 1.1 9.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) KOW PF00467.29 KLO05297.1 - 3.6 7.7 8.3 11 6.2 0.0 3.9 4 0 0 4 4 4 0 KOW motif DUF2986 PF11661.8 KLO05298.1 - 0.7 10.5 5.3 5.3 7.7 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) NusB PF01029.18 KLO05304.1 - 0.047 13.9 0.1 0.053 13.8 0.1 1.1 1 0 0 1 1 1 0 NusB family WD40 PF00400.32 KLO05305.1 - 2.6e-08 34.4 8.5 0.00013 22.7 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO05305.1 - 0.0016 18.7 0.0 0.73 10.2 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_9 PF13901.6 KLO05307.1 - 0.037 14.0 0.7 0.056 13.4 0.7 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DNA_pol_B PF00136.21 KLO05308.1 - 1.1e-146 489.2 2.8 5.7e-146 486.8 1.4 2.1 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KLO05308.1 - 9.2e-85 284.7 0.0 2e-84 283.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KLO05308.1 - 5.9e-17 61.9 7.0 1.4e-16 60.7 7.0 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KLO05308.1 - 0.0017 17.3 0.8 0.0081 15.1 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KLO05308.1 - 0.0048 16.6 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Ribosomal_L34 PF00468.17 KLO05310.1 - 9.9e-17 60.6 11.1 1.4e-16 60.1 11.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 DEP PF00610.21 KLO05311.1 - 1.7e-13 50.4 0.0 2.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ribosomal_L7Ae PF01248.26 KLO05312.1 - 1.7e-20 72.5 0.0 2.1e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family F-box-like PF12937.7 KLO05313.1 - 0.017 15.0 0.2 0.017 15.0 0.2 2.5 3 0 0 3 3 3 0 F-box-like Methyltransf_23 PF13489.6 KLO05315.1 - 9.7e-10 38.5 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO05315.1 - 4.2e-08 33.7 0.0 9.3e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO05315.1 - 2.8e-05 24.8 0.0 8.5e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO05315.1 - 6.7e-05 22.7 0.0 9.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KLO05315.1 - 0.0014 18.6 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.12 KLO05315.1 - 0.0038 17.9 0.0 0.0068 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KLO05315.1 - 0.0073 14.9 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 KLO05315.1 - 0.016 14.5 0.0 0.04 13.2 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF5374 PF17344.2 KLO05315.1 - 0.065 13.2 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5374) zf-MYND PF01753.18 KLO05318.1 - 3.1e-07 30.4 6.9 3.1e-07 30.4 6.9 2.6 2 0 0 2 2 2 1 MYND finger CBM_1 PF00734.18 KLO05319.1 - 0.12 12.3 0.8 0.26 11.3 0.8 1.5 1 0 0 1 1 1 0 Fungal cellulose binding domain DUF2299 PF10061.9 KLO05321.1 - 0.21 11.3 0.0 0.31 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) KDZ PF18758.1 KLO05324.1 - 2.9e-51 174.2 0.8 2.9e-51 174.2 0.8 1.9 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO05324.1 - 7e-30 103.4 2.5 1.4e-29 102.4 2.5 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO05324.1 - 5.1e-05 23.4 0.6 0.00012 22.2 0.6 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Goodbye PF17109.5 KLO05324.1 - 0.097 13.1 0.1 1.5 9.3 0.0 2.7 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain KOW PF00467.29 KLO05325.1 - 3.9e-08 33.0 13.5 0.014 15.3 0.9 4.6 5 0 0 5 5 5 3 KOW motif Spt5-NGN PF03439.13 KLO05325.1 - 1.1e-07 31.6 0.0 3.1e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF3912 PF13051.6 KLO05325.1 - 0.022 15.0 0.6 0.15 12.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) Spt5_N PF11942.8 KLO05325.1 - 0.05 14.6 0.3 0.12 13.4 0.3 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF5127 PF17168.4 KLO05329.1 - 1e-54 185.8 0.1 1.7e-54 185.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO05329.1 - 4.7e-39 133.8 0.1 9.8e-39 132.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO05329.1 - 2.1e-25 90.1 0.0 4.5e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Glyco_hydro_52 PF03512.13 KLO05329.1 - 7e-05 22.0 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 52 Bac_rhamnosid6H PF17389.2 KLO05329.1 - 0.098 11.9 1.1 0.34 10.1 0.0 2.1 2 1 0 2 2 2 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF2273 PF10031.9 KLO05329.1 - 0.37 10.8 6.8 0.87 9.7 6.8 1.6 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) APH PF01636.23 KLO05330.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family HTH_Tnp_Mu_1 PF02316.16 KLO05332.1 - 0.0098 16.1 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Mu DNA-binding domain APH PF01636.23 KLO05332.1 - 0.011 15.7 0.9 0.17 11.7 0.3 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Aldo_ket_red PF00248.21 KLO05337.1 - 7.7e-65 219.0 0.0 1e-64 218.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 KLO05338.1 - 1.2e-07 31.5 0.1 5.1e-07 29.5 0.1 2.1 1 0 0 1 1 1 1 F-box-like MWFE PF15879.5 KLO05343.1 - 1.2e-23 83.0 0.1 1.5e-23 82.7 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit G10 PF01125.17 KLO05345.1 - 1.2e-64 216.5 7.4 1.4e-64 216.3 7.4 1.0 1 0 0 1 1 1 1 G10 protein DUF5347 PF17282.2 KLO05345.1 - 0.018 15.3 0.1 0.027 14.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5347) DNA_RNApol_7kD PF03604.13 KLO05345.1 - 0.046 13.4 4.4 0.046 13.4 4.4 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Velvet PF11754.8 KLO05346.1 - 2.5e-81 273.3 22.0 1e-77 261.5 22.0 3.1 1 1 0 1 1 1 1 Velvet factor PPR_2 PF13041.6 KLO05347.1 - 6.1e-35 119.2 0.1 7.8e-11 42.0 0.1 9.8 7 3 4 11 11 11 7 PPR repeat family PPR_3 PF13812.6 KLO05347.1 - 1.5e-29 101.9 0.0 1.7e-08 34.4 0.0 7.6 7 1 1 8 8 8 5 Pentatricopeptide repeat domain PPR PF01535.20 KLO05347.1 - 7.9e-28 94.7 9.3 0.0089 16.2 0.1 12.1 13 0 0 13 13 13 8 PPR repeat PPR_1 PF12854.7 KLO05347.1 - 6e-18 64.2 0.0 5.9e-06 25.9 0.0 6.9 7 0 0 7 7 7 4 PPR repeat PPR_long PF17177.4 KLO05347.1 - 1.3e-17 63.9 0.1 5.5e-09 35.7 0.0 4.7 3 2 1 5 5 5 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KLO05347.1 - 1.1e-06 28.9 10.9 5.9 8.0 0.2 8.3 8 1 1 9 9 9 1 Tetratricopeptide repeat Ntox34 PF15606.6 KLO05347.1 - 0.047 13.8 0.0 0.3 11.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial toxin 34 RPM2 PF08579.11 KLO05347.1 - 0.051 14.0 0.0 52 4.3 0.0 3.9 4 0 0 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) REV PF00424.18 KLO05347.1 - 0.061 13.3 0.3 0.21 11.6 0.3 1.9 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) TPR_6 PF13174.6 KLO05347.1 - 0.92 10.3 12.1 47 4.9 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat SBDS PF01172.18 KLO05348.1 - 1.8e-10 40.7 0.4 2.7e-10 40.2 0.4 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein OrfB_Zn_ribbon PF07282.11 KLO05350.1 - 0.15 12.0 1.7 0.33 10.9 1.7 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ribosomal_L7Ae PF01248.26 KLO05353.1 - 2.4e-26 91.3 2.2 3.1e-26 90.9 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FliM PF02154.15 KLO05353.1 - 0.19 11.6 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Arb1 PF09692.10 KLO05354.1 - 2e-11 43.7 0.4 5.8e-11 42.2 0.6 1.6 2 0 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 gag_pre-integrs PF13976.6 KLO05358.1 - 0.00029 20.6 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain Spt5-NGN PF03439.13 KLO05360.1 - 1.9e-12 46.9 0.0 4.5e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DHC PF09626.10 KLO05360.1 - 0.0003 21.6 0.0 0.011 16.5 0.0 2.5 2 0 0 2 2 2 1 Dihaem cytochrome c KOW PF00467.29 KLO05360.1 - 0.0038 17.1 0.5 0.0038 17.1 0.5 4.4 5 0 0 5 5 5 2 KOW motif LAMTOR5 PF16672.5 KLO05360.1 - 0.057 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 CSD2 PF17876.1 KLO05360.1 - 0.11 12.7 0.9 0.57 10.4 0.2 2.7 2 0 0 2 2 2 0 Cold shock domain DUF4438 PF14505.6 KLO05360.1 - 0.86 8.5 3.1 4.6 6.1 0.1 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4438) PPP4R2 PF09184.11 KLO05362.1 - 0.32 10.5 8.7 0.65 9.5 8.7 1.4 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 KLO05362.1 - 0.58 9.9 8.6 1.4 8.6 8.6 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TMEM119 PF15724.5 KLO05362.1 - 4.3 7.3 10.8 9 6.3 10.8 1.4 1 0 0 1 1 1 0 TMEM119 family Fe-S_biosyn PF01521.20 KLO05365.1 - 5.2e-06 26.6 0.0 6.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis NFACT-R_1 PF05670.13 KLO05366.1 - 6.8e-41 139.3 0.4 1.6e-40 138.1 0.0 1.7 2 0 0 2 2 2 1 NFACT protein RNA binding domain PIEZO PF15917.5 KLO05366.1 - 1.1 8.6 7.1 1.5 8.2 7.1 1.1 1 0 0 1 1 1 0 Piezo Pkinase PF00069.25 KLO05367.1 - 8.5e-15 54.8 0.0 9.9e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05367.1 - 6.5e-14 51.8 0.0 7.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_MCEL PF03291.16 KLO05368.1 - 3.2e-63 213.8 0.0 7.1e-63 212.7 0.0 1.4 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KLO05368.1 - 1.1e-09 38.9 0.0 2.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO05368.1 - 2.3e-08 34.0 0.0 3.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO05368.1 - 1.5e-07 32.0 0.1 4.1e-07 30.6 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO05368.1 - 3.7e-06 26.9 0.0 6.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.25 KLO05368.1 - 5.1e-06 26.1 0.0 8.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05368.1 - 1.6e-05 24.3 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_12 PF08242.12 KLO05368.1 - 8.1e-05 23.3 0.0 0.0009 20.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KLO05368.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Flexi_CP PF00286.20 KLO05371.1 - 0.044 13.7 0.4 0.078 12.9 0.4 1.5 1 1 0 1 1 1 0 Viral coat protein TssN PF17555.2 KLO05372.1 - 0.18 11.2 1.5 1.4 8.2 0.3 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssN NADH_dehy_S2_C PF06444.11 KLO05372.1 - 0.25 11.9 3.3 29 5.3 0.1 3.6 3 0 0 3 3 3 0 NADH dehydrogenase subunit 2 C-terminus Glyco_hydro_15 PF00723.21 KLO05374.1 - 6.4e-93 312.0 0.0 7.6e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KLO05374.1 - 1.6e-27 95.2 0.3 3.4e-27 94.2 0.3 1.6 1 0 0 1 1 1 1 Starch binding domain Methyltransf_33 PF10017.9 KLO05375.1 - 2.7e-71 240.2 0.0 8.7e-71 238.6 0.0 1.7 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KLO05375.1 - 2.3e-22 79.9 0.2 6.7e-14 52.1 0.0 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KLO05375.1 - 1e-05 26.1 1.1 2.5e-05 24.8 1.1 1.7 1 0 0 1 1 1 1 DinB superfamily Herpes_TK_C PF08465.10 KLO05376.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal GPI-anchored PF10342.9 KLO05377.1 - 1.3e-07 32.2 0.4 1.7e-07 31.9 0.4 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Sugar_tr PF00083.24 KLO05379.1 - 4.9e-39 134.5 15.7 8.7e-23 80.9 1.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KLO05379.1 - 9.6e-20 70.8 35.3 1e-12 47.6 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KLO05379.1 - 6.3e-05 22.4 3.4 6.3e-05 22.4 3.4 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB IPK PF03770.16 KLO05380.1 - 0.11 12.3 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Inositol polyphosphate kinase 2Fe-2S_thioredx PF01257.19 KLO05380.1 - 0.26 11.1 0.8 2.2 8.2 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin F-box-like PF12937.7 KLO05382.1 - 0.00039 20.3 2.4 0.0011 18.8 2.4 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05382.1 - 0.34 10.9 3.4 0.58 10.1 1.4 2.5 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO05383.1 - 3.7e-07 29.9 1.7 1.3e-06 28.2 1.7 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO05384.1 - 0.00072 19.4 3.1 0.00072 19.4 3.1 2.8 3 1 0 3 3 3 1 F-box-like F-box-like PF12937.7 KLO05385.1 - 3.7e-07 29.9 1.8 3.7e-07 29.9 1.8 2.8 2 0 0 2 2 2 1 F-box-like UBN_AB PF14075.6 KLO05386.1 - 0.052 13.3 0.1 0.076 12.7 0.1 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Methyltransf_5 PF01795.19 KLO05387.1 - 0.0013 18.3 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 MraW methylase family VasL PF12486.8 KLO05387.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system, EvfB, or VasL Y_phosphatase PF00102.27 KLO05390.1 - 2.3e-57 194.3 0.0 4.4e-32 111.5 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.20 KLO05390.1 - 3.4e-06 27.5 0.0 7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 KLO05390.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Macoilin PF09726.9 KLO05390.1 - 4.4 5.7 8.4 7.8 4.9 8.4 1.3 1 0 0 1 1 1 0 Macoilin family SNF2_N PF00176.23 KLO05391.1 - 8.5e-72 241.8 0.5 1.7e-71 240.8 0.5 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO05391.1 - 8.3e-21 74.4 2.2 9.1e-19 67.8 0.0 3.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 KLO05391.1 - 9.9e-20 70.6 8.3 9.9e-20 70.6 8.3 2.8 3 0 0 3 3 3 1 HSA Bromodomain PF00439.25 KLO05391.1 - 1.3e-17 63.6 0.1 5.3e-17 61.7 0.1 2.1 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 KLO05391.1 - 1.5e-09 38.3 0.0 1.5e-09 38.3 0.0 3.9 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KLO05391.1 - 1.7e-09 37.3 0.0 7.2e-09 35.3 0.0 2.2 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 KLO05391.1 - 9.3e-09 35.5 0.0 5.5e-08 33.0 0.0 2.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ku PF02735.16 KLO05392.1 - 1.3e-32 113.2 0.1 2.4e-32 112.3 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KLO05392.1 - 1.3e-22 80.2 0.0 2.9e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 KLO05392.1 - 6.1e-10 39.2 0.0 1.6e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KLO05392.1 - 2.3e-05 24.7 0.0 9.1e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KLO05392.1 - 0.0014 19.3 0.0 0.0047 17.5 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 KLO05392.1 - 0.027 15.2 0.0 0.027 15.2 0.0 3.7 3 1 1 4 4 4 0 Ku70/Ku80 C-terminal arm Phostensin PF13914.6 KLO05392.1 - 0.063 13.9 1.0 0.36 11.5 0.0 2.5 2 0 0 2 2 2 0 Phostensin PP1-binding and SH3-binding region Pox_Ag35 PF03286.14 KLO05392.1 - 0.74 9.6 19.4 0.11 12.2 5.3 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF4330 PF14221.6 KLO05392.1 - 1.6 8.9 3.8 2.6 8.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4330) CHAT PF12770.7 KLO05393.1 - 1.5e-31 109.9 0.1 1.8e-31 109.6 0.1 1.1 1 0 0 1 1 1 1 CHAT domain Acetyltransf_7 PF13508.7 KLO05394.1 - 0.00025 21.4 0.0 0.00027 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO05394.1 - 0.00081 19.6 0.0 0.00094 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KLO05394.1 - 0.0084 16.0 0.0 0.0098 15.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO05395.1 - 2.2e-08 34.4 0.0 4.7e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KLO05395.1 - 2.9e-08 34.0 0.0 6e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO05395.1 - 3.1e-07 30.4 0.0 7.5e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO05395.1 - 4e-05 23.5 0.0 7.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KLO05395.1 - 0.014 15.6 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 KLO05395.1 - 0.039 13.4 0.0 0.089 12.3 0.0 1.5 1 1 0 1 1 1 0 Putative acetyl-transferase Pkinase PF00069.25 KLO05396.1 - 2.5e-37 128.7 0.0 3.3e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05396.1 - 5.5e-34 117.6 0.0 7.2e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO05396.1 - 0.00016 20.6 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO05396.1 - 0.0025 17.2 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like POM121 PF15229.6 KLO05396.1 - 0.0051 16.5 0.5 0.0094 15.6 0.5 1.3 1 0 0 1 1 1 1 POM121 family RIO1 PF01163.22 KLO05396.1 - 0.079 12.5 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 RIO1 family p450 PF00067.22 KLO05397.1 - 1.9e-59 201.7 0.0 2.7e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_7 PF13508.7 KLO05398.1 - 1.1e-11 45.0 0.0 3.8e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO05398.1 - 6.3e-08 32.9 0.0 1.1e-07 32.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KLO05398.1 - 6.1e-06 26.2 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO05398.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein MOZ_SAS PF01853.18 KLO05398.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Sarcoglycan_1 PF04790.13 KLO05400.1 - 2.7 7.3 4.8 0.54 9.6 0.5 1.8 2 0 0 2 2 2 0 Sarcoglycan complex subunit protein F-box-like PF12937.7 KLO05401.1 - 1.7e-05 24.6 0.5 6e-05 22.9 0.5 2.0 1 1 0 1 1 1 1 F-box-like Acetyltransf_7 PF13508.7 KLO05402.1 - 1.7e-08 34.7 0.0 2.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO05402.1 - 2.3e-07 30.8 0.0 3.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO05402.1 - 4.2e-07 30.2 0.0 5.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PanZ PF12568.8 KLO05402.1 - 0.0032 17.2 0.0 0.028 14.2 0.0 1.9 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 KLO05402.1 - 0.07 13.3 0.0 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.18 KLO05402.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family BTB PF00651.31 KLO05403.1 - 3.6e-07 30.4 0.1 1e-06 28.9 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain Terpene_synth PF01397.21 KLO05403.1 - 0.092 12.4 0.0 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain zf-3CxxC PF13695.6 KLO05403.1 - 0.11 13.0 0.9 0.24 11.9 0.9 1.5 1 0 0 1 1 1 0 Zinc-binding domain Involucrin_N PF10583.9 KLO05403.1 - 0.24 12.0 2.9 0.44 11.2 2.9 1.4 1 0 0 1 1 1 0 Involucrin of squamous epithelia N-terminus BTB PF00651.31 KLO05404.1 - 1.6e-05 25.1 0.0 4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DEAD PF00270.29 KLO05405.1 - 7.8e-12 45.3 0.1 2.4e-11 43.7 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO05405.1 - 5.2e-10 39.7 0.0 1.8e-09 37.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO05405.1 - 0.00033 20.7 0.0 0.0015 18.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RasGAP_C PF03836.15 KLO05405.1 - 0.0017 18.5 0.4 0.0039 17.3 0.4 1.6 1 0 0 1 1 1 1 RasGAP C-terminus Senescence PF06911.12 KLO05405.1 - 0.047 14.0 3.3 0.14 12.5 3.3 1.8 1 0 0 1 1 1 0 Senescence-associated protein DUF515 PF04415.12 KLO05405.1 - 3.4 6.0 8.5 6.1 5.1 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF5089 PF17002.5 KLO05406.1 - 0.015 15.2 5.8 0.024 14.5 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) CENP-B_dimeris PF09026.10 KLO05406.1 - 0.21 12.0 9.1 0.75 10.2 9.1 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BTB PF00651.31 KLO05407.1 - 0.00029 21.0 0.0 0.00058 20.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO05408.1 - 0.00035 20.8 0.0 0.00064 19.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF4428 PF14471.6 KLO05408.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) BTB PF00651.31 KLO05409.1 - 1.9e-06 28.0 0.0 2.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO05410.1 - 2e-05 24.7 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Corona_M PF01635.18 KLO05413.1 - 0.59 9.4 7.3 1.2 8.4 7.3 1.5 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein SWIM PF04434.17 KLO05416.1 - 0.098 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 SWIM zinc finger Methyltransf_2 PF00891.18 KLO05417.1 - 5.1e-16 58.6 0.0 1.4e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain p450 PF00067.22 KLO05418.1 - 6.4e-65 219.7 0.0 1.2e-64 218.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 HNH_2 PF13391.6 KLO05419.1 - 4.4e-07 29.9 0.2 1.3e-06 28.5 0.2 1.8 1 0 0 1 1 1 1 HNH endonuclease ChW PF07538.11 KLO05421.1 - 0.094 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Clostridial hydrophobic W Spt5-NGN PF03439.13 KLO05423.1 - 4.8e-09 36.0 0.1 1.2e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KLO05423.1 - 4.5e-06 26.4 21.1 0.048 13.6 0.3 6.2 6 0 0 6 6 6 3 KOW motif DUF3912 PF13051.6 KLO05423.1 - 0.56 10.5 4.8 0.42 10.9 0.1 3.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3912) DUF3525 PF12039.8 KLO05426.1 - 0.093 11.4 0.8 0.15 10.7 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) His_Phos_2 PF00328.22 KLO05428.1 - 0.00065 19.2 0.5 0.039 13.3 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DASH_Duo1 PF08651.10 KLO05430.1 - 0.0021 17.8 0.5 0.026 14.3 0.2 2.5 2 0 0 2 2 2 1 DASH complex subunit Duo1 Mod_r PF07200.13 KLO05430.1 - 0.026 14.6 3.9 0.06 13.4 3.9 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF812 PF05667.11 KLO05430.1 - 0.039 12.8 6.3 0.058 12.3 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spc7 PF08317.11 KLO05430.1 - 0.086 11.7 6.8 0.15 10.9 6.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KLO05430.1 - 0.091 12.8 1.0 0.2 11.7 1.0 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3818 PF12825.7 KLO05430.1 - 0.093 11.7 1.5 0.49 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) Epsilon_antitox PF08998.11 KLO05430.1 - 0.13 12.5 0.1 9.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Bacterial epsilon antitoxin DUF4407 PF14362.6 KLO05430.1 - 0.37 10.1 6.5 0.64 9.3 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KLO05430.1 - 0.48 9.5 5.3 0.24 10.5 3.3 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 KLO05430.1 - 0.54 10.6 7.8 1.2 9.5 7.8 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CorA PF01544.18 KLO05430.1 - 0.71 9.1 2.7 1.5 8.1 2.7 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Phage_GP20 PF06810.11 KLO05430.1 - 1.8 8.4 7.5 3.6 7.4 5.6 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 APG6_N PF17675.1 KLO05430.1 - 2.1 8.9 10.6 4.2 7.9 9.4 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region HSP70 PF00012.20 KLO05431.1 - 0.00051 18.4 0.1 0.0018 16.5 0.1 1.7 1 1 0 1 1 1 1 Hsp70 protein 2-Hacid_dh_C PF02826.19 KLO05432.1 - 6.1e-52 175.5 0.0 9.1e-52 175.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KLO05432.1 - 4.2e-30 104.1 0.1 4.8e-30 103.9 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KLO05432.1 - 3.8e-06 27.2 0.1 3.6e-05 24.0 0.0 2.3 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 KLO05432.1 - 0.0018 19.1 0.0 0.076 13.8 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.12 KLO05432.1 - 0.0075 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KLO05432.1 - 0.0076 16.8 0.0 0.029 15.0 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding_2 PF13380.6 KLO05432.1 - 0.031 14.8 0.1 0.064 13.7 0.1 1.5 1 0 0 1 1 1 0 CoA binding domain Glu_dehyd_C PF16912.5 KLO05432.1 - 0.033 13.7 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_C PF03720.15 KLO05432.1 - 0.065 13.7 0.0 0.36 11.3 0.0 2.2 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain HSP70 PF00012.20 KLO05433.1 - 0.013 13.7 0.0 0.023 12.9 0.0 1.4 1 0 0 1 1 1 0 Hsp70 protein StbA PF06406.11 KLO05433.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 StbA protein SRP_TPR_like PF17004.5 KLO05434.1 - 1.7e-14 53.9 0.4 3e-14 53.0 0.4 1.5 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 KLO05434.1 - 4.2e-08 33.5 0.1 4.2e-08 33.5 0.1 2.9 3 0 0 3 3 3 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 KLO05434.1 - 6.6e-06 26.3 1.8 0.011 16.0 0.5 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KLO05434.1 - 0.0024 18.3 2.9 0.025 15.1 0.4 3.0 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KLO05434.1 - 0.018 15.1 0.8 22 5.5 0.3 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TetR_C_37 PF18665.1 KLO05434.1 - 0.082 13.5 0.6 0.72 10.5 0.1 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_15 PF13429.6 KLO05434.1 - 0.1 11.8 4.4 0.87 8.7 0.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KLO05434.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat ATG16 PF08614.11 KLO05434.1 - 0.76 10.0 6.2 0.11 12.7 1.0 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) His_Phos_2 PF00328.22 KLO05435.1 - 0.014 14.8 0.1 4.5 6.5 0.0 2.5 2 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Phage_r1t_holin PF16945.5 KLO05435.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin DUF2321 PF10083.9 KLO05435.1 - 0.15 11.7 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) His_Phos_2 PF00328.22 KLO05436.1 - 0.0016 17.9 1.2 0.059 12.7 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) BTB PF00651.31 KLO05437.1 - 1.5e-09 38.1 2.0 1.7e-09 37.9 0.2 1.9 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 KLO05437.1 - 0.0021 18.2 0.1 0.0042 17.2 0.1 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Abhydrolase_6 PF12697.7 KLO05438.1 - 1.6e-15 58.4 3.3 2e-15 58.0 3.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO05438.1 - 2.8e-08 33.7 0.1 3.1e-07 30.3 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO05438.1 - 2.9e-07 30.0 0.1 2.1e-06 27.2 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KLO05438.1 - 0.038 13.7 0.0 7.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KLO05439.1 - 5.4e-15 56.6 1.5 6.7e-15 56.3 1.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO05439.1 - 5.3e-13 49.2 0.2 8.4e-11 42.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO05439.1 - 3.9e-08 32.9 0.0 6.1e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KLO05439.1 - 0.0033 17.2 0.1 2.6 7.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family zf-MYND PF01753.18 KLO05440.1 - 1.1e-11 44.5 12.2 1.7e-11 44.0 12.2 1.3 1 0 0 1 1 1 1 MYND finger DUF4314 PF14192.6 KLO05440.1 - 0.13 12.1 0.0 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4314) zf-C6H2 PF15801.5 KLO05440.1 - 2.2 8.7 8.7 4.2 7.8 8.7 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 KLO05440.1 - 2.6 8.0 6.8 4.2 7.3 6.8 1.3 1 0 0 1 1 1 0 HIT zinc finger AAA_18 PF13238.6 KLO05441.1 - 3.7e-08 34.0 0.0 5.4e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KLO05441.1 - 8.9e-06 25.9 0.0 1e-05 25.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain Pkinase_Tyr PF07714.17 KLO05442.1 - 3.3e-38 131.4 0.0 2.3e-37 128.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KLO05442.1 - 2.5e-32 112.3 0.0 5.4e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO05442.1 - 0.0035 16.7 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KLO05442.1 - 0.0091 15.1 0.1 0.017 14.2 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KLO05442.1 - 0.017 15.0 0.1 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KLO05442.1 - 0.054 12.9 0.1 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HPD PF05044.12 KLO05442.1 - 0.16 11.8 1.5 2.6 7.9 0.2 2.3 2 0 0 2 2 2 0 Homeo-prospero domain DUF4218 PF13960.6 KLO05444.1 - 0.012 15.3 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Nop14 PF04147.12 KLO05444.1 - 0.14 10.4 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Nop14-like family Cep3 PF16846.5 KLO05445.1 - 0.12 10.8 0.0 0.23 9.9 0.0 1.4 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B SOBP PF15279.6 KLO05445.1 - 0.68 10.5 5.4 0.97 10.0 5.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CENP-H PF05837.12 KLO05445.1 - 0.96 9.9 4.8 3.7 8.0 2.8 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) NOA36 PF06524.12 KLO05445.1 - 5.3 6.3 6.6 13 5.0 6.6 1.6 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 KLO05446.1 - 0.0036 16.7 7.2 0.0036 16.7 7.2 1.7 2 0 0 2 2 2 1 BUD22 Ecm29 PF13001.7 KLO05446.1 - 0.032 12.9 0.2 0.05 12.3 0.2 1.2 1 0 0 1 1 1 0 Proteasome stabiliser Zein-binding PF04576.15 KLO05446.1 - 0.5 10.7 6.2 0.11 12.7 2.7 1.7 2 0 0 2 2 2 0 Zein-binding CDC27 PF09507.10 KLO05446.1 - 0.72 9.2 18.6 1.6 8.1 18.6 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SurA_N_2 PF13623.6 KLO05446.1 - 1.5 8.6 4.3 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 SurA N-terminal domain Cwf_Cwc_15 PF04889.12 KLO05446.1 - 2 8.1 10.3 0.15 11.8 4.1 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KLO05446.1 - 2.1 7.6 4.9 3.5 6.9 4.9 1.2 1 0 0 1 1 1 0 NOA36 protein Pkinase_Tyr PF07714.17 KLO05450.1 - 9.3e-36 123.4 0.0 1.4e-35 122.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO05450.1 - 5e-35 121.1 0.0 6e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KLO05450.1 - 0.019 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KLO05450.1 - 0.019 14.9 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO05450.1 - 0.034 12.9 0.1 0.045 12.5 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KLO05450.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Helicase_C PF00271.31 KLO05452.1 - 2e-14 53.9 0.0 2e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO05452.1 - 1.2e-10 41.5 0.0 2.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SecA_DEAD PF07517.14 KLO05452.1 - 0.0097 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain T4SS-DNA_transf PF02534.14 KLO05452.1 - 0.12 11.2 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Pkinase PF00069.25 KLO05454.1 - 1.3e-26 93.5 0.0 1.6e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05454.1 - 2.2e-26 92.7 0.0 2.5e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase C2-set_2 PF08205.12 KLO05454.1 - 0.0043 17.1 0.0 0.0076 16.3 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain RIO1 PF01163.22 KLO05454.1 - 0.0053 16.4 0.0 0.0066 16.1 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KLO05454.1 - 0.0057 16.6 0.0 0.0069 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO05454.1 - 0.18 11.1 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Sacchrp_dh_C PF16653.5 KLO05456.1 - 7e-87 291.9 0.0 1.7e-86 290.7 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 KLO05456.1 - 4.1e-65 218.7 0.0 7.7e-65 217.8 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Sacchrp_dh_NADP PF03435.18 KLO05456.1 - 8.5e-26 90.7 2.4 1.8e-25 89.7 0.6 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Spermine_synt_N PF17284.2 KLO05456.1 - 1.9e-25 88.5 0.2 6.7e-25 86.7 0.0 2.0 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Shikimate_DH PF01488.20 KLO05456.1 - 3.6e-07 30.3 0.2 2.8e-06 27.5 0.1 2.3 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.6 KLO05456.1 - 6.4e-07 30.0 0.0 0.0001 22.9 0.0 3.3 3 0 0 3 3 3 1 Methyltransferase domain NAD_binding_10 PF13460.6 KLO05456.1 - 0.00067 19.6 0.3 0.0011 18.9 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_12 PF08242.12 KLO05456.1 - 0.0026 18.5 0.1 0.013 16.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 KLO05456.1 - 0.017 14.4 0.0 0.89 8.8 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 KLO05456.1 - 0.018 15.6 0.1 0.042 14.4 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_18 PF12847.7 KLO05456.1 - 0.058 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KLO05456.1 - 0.092 12.3 0.0 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain GFO_IDH_MocA PF01408.22 KLO05456.1 - 0.13 13.1 0.3 0.49 11.2 0.1 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold FGGY_C PF02782.16 KLO05458.1 - 6.1e-05 22.8 0.0 0.00022 21.0 0.0 2.0 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Rer1 PF03248.13 KLO05462.1 - 5.7 6.6 10.4 2.4 7.9 0.5 3.0 3 0 0 3 3 3 0 Rer1 family DUF368 PF04018.13 KLO05463.1 - 0.15 11.6 10.3 0.1 12.1 8.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF368) CE2_N PF17996.1 KLO05468.1 - 0.00025 21.0 0.2 0.081 12.9 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Syndecan PF01034.20 KLO05468.1 - 0.004 17.1 0.1 0.008 16.1 0.1 1.4 1 0 0 1 1 1 1 Syndecan domain PTP_tm PF18861.1 KLO05468.1 - 0.07 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J SKG6 PF08693.10 KLO05469.1 - 0.0018 17.6 0.3 0.0048 16.3 0.3 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF202 PF02656.15 KLO05469.1 - 0.03 14.7 0.2 0.073 13.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF202) PTP_tm PF18861.1 KLO05469.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF5326 PF17260.2 KLO05469.1 - 0.34 11.1 0.1 0.34 11.1 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5326) Podoplanin PF05808.11 KLO05469.1 - 0.57 10.3 5.5 0.16 12.1 0.3 2.4 2 0 0 2 2 2 0 Podoplanin Pex14_N PF04695.13 KLO05469.1 - 6.8 7.3 9.8 11 6.7 2.9 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DSHCT PF08148.12 KLO05470.1 - 2.2e-50 170.5 0.1 4.5e-50 169.5 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KLO05470.1 - 1.1e-31 109.4 0.0 1.8e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KLO05470.1 - 2.2e-23 83.6 0.0 3.3e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KLO05470.1 - 3e-19 69.5 0.1 7.1e-19 68.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO05470.1 - 4.7e-07 30.0 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KLO05470.1 - 3e-05 24.3 0.0 0.0001 22.6 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ComX PF05952.12 KLO05470.1 - 0.15 12.0 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 Bacillus competence pheromone ComX DUF3516 PF12029.8 KLO05470.1 - 0.32 10.0 2.4 0.31 10.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3516) O-FucT PF10250.9 KLO05472.1 - 8.9e-10 38.8 0.0 3e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase U6-snRNA_bdg PF10596.9 KLO05472.1 - 0.016 15.2 0.1 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 U6-snRNA interacting domain of PrP8 DUF5010 PF16402.5 KLO05472.1 - 0.064 12.1 0.0 0.13 11.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) VIT_2 PF13757.6 KLO05474.1 - 0.096 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain WD40 PF00400.32 KLO05475.1 - 1.1e-52 174.8 32.2 5.3e-10 39.7 0.2 8.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO05475.1 - 1.1e-19 70.5 5.4 0.016 15.5 0.0 7.7 2 1 6 8 8 7 6 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KLO05475.1 - 1.6e-10 41.1 0.0 0.0021 18.0 0.0 3.8 3 2 0 3 3 3 2 NACHT domain Patatin PF01734.22 KLO05475.1 - 1.8e-09 38.1 0.4 1.2e-08 35.4 0.4 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase AAA_22 PF13401.6 KLO05475.1 - 3.8e-09 36.9 0.0 0.00054 20.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KLO05475.1 - 4.5e-09 36.9 0.0 0.00038 20.9 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.22 KLO05475.1 - 2.5e-07 30.2 0.0 0.00017 20.9 0.0 3.1 2 1 0 2 2 2 1 NB-ARC domain Ge1_WD40 PF16529.5 KLO05475.1 - 4.5e-07 29.2 9.3 1 8.2 0.0 6.4 3 1 3 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_18 PF13238.6 KLO05475.1 - 6.2e-07 30.0 0.0 0.034 14.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 KLO05475.1 - 3.1e-06 27.6 0.0 0.07 13.6 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KLO05475.1 - 2e-05 24.9 0.0 0.21 12.0 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_33 PF13671.6 KLO05475.1 - 4.4e-05 23.7 0.0 0.42 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain KAP_NTPase PF07693.14 KLO05475.1 - 0.00015 21.1 0.0 0.032 13.5 0.0 2.4 2 0 0 2 2 2 1 KAP family P-loop domain AAA_24 PF13479.6 KLO05475.1 - 0.00016 21.5 0.0 0.055 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KLO05475.1 - 0.00021 21.7 0.0 0.38 11.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KLO05475.1 - 0.00047 20.7 0.0 0.48 10.9 0.0 3.5 4 0 0 4 4 3 1 ABC transporter ATPase_2 PF01637.18 KLO05475.1 - 0.0017 18.3 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KLO05475.1 - 0.0036 17.0 0.0 0.48 10.1 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 KLO05475.1 - 0.0039 17.2 0.0 1.2 9.2 0.0 3.6 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KLO05475.1 - 0.006 16.6 0.0 1.5 9.0 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Frtz PF11768.8 KLO05475.1 - 0.0079 14.6 0.0 0.2 9.9 0.0 2.5 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Zeta_toxin PF06414.12 KLO05475.1 - 0.012 14.9 0.0 0.71 9.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.20 KLO05475.1 - 0.019 14.9 0.0 6.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase PD40 PF07676.12 KLO05475.1 - 0.022 14.7 0.1 1.7e+02 2.3 0.0 5.1 6 0 0 6 6 5 0 WD40-like Beta Propeller Repeat AAA_25 PF13481.6 KLO05475.1 - 0.026 14.1 0.1 11 5.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 KLO05475.1 - 0.026 14.8 0.0 4.7 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KLO05475.1 - 0.031 14.2 0.0 3.4 7.5 0.0 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain Roc PF08477.13 KLO05475.1 - 0.04 14.1 0.0 17 5.6 0.0 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 KLO05475.1 - 0.045 13.6 0.0 8 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Nbas_N PF15492.6 KLO05475.1 - 0.078 12.3 3.4 9 5.5 0.0 4.2 2 2 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal ADK PF00406.22 KLO05475.1 - 0.085 13.0 0.0 34 4.5 0.0 3.4 3 0 0 3 3 3 0 Adenylate kinase PPV_E1_C PF00519.17 KLO05475.1 - 0.093 11.5 0.0 5.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Papillomavirus helicase RsgA_GTPase PF03193.16 KLO05475.1 - 0.1 12.5 0.0 0.97 9.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Rad51 PF08423.11 KLO05475.1 - 0.11 11.7 0.0 0.29 10.3 0.0 1.6 2 0 0 2 2 1 0 Rad51 Rib_hydrolayse PF02267.17 KLO05475.1 - 0.15 11.4 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosyl cyclase AAA_5 PF07728.14 KLO05475.1 - 0.17 11.9 0.0 4.1 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Patatin PF01734.22 KLO05476.1 - 3e-13 50.4 0.1 3.4e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase NUC202 PF08166.12 KLO05476.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 NUC202 domain Spt5-NGN PF03439.13 KLO05479.1 - 2.9e-12 46.3 0.0 7.6e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DHC PF09626.10 KLO05479.1 - 0.0014 19.5 0.3 0.004 18.0 0.0 1.9 2 0 0 2 2 2 1 Dihaem cytochrome c KOW PF00467.29 KLO05479.1 - 0.0031 17.4 0.6 0.0031 17.4 0.6 5.0 5 0 0 5 5 5 1 KOW motif SH3_15 PF18346.1 KLO05479.1 - 0.31 11.4 5.0 0.52 10.7 0.7 3.4 3 1 0 3 3 3 0 Mind bomb SH3 repeat domain SH3_13 PF18335.1 KLO05479.1 - 0.56 10.1 3.0 3 7.8 0.9 2.8 3 0 0 3 3 3 0 ATP-dependent RecD-like DNA helicase SH3 domain CCDC-167 PF15188.6 KLO05481.1 - 0.042 14.2 1.3 0.089 13.1 1.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Spt5_N PF11942.8 KLO05482.1 - 0.028 15.4 10.8 0.028 15.4 10.8 3.3 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Vfa1 PF08432.10 KLO05482.1 - 7.4 6.9 34.8 0.35 11.2 10.3 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 GEMIN8 PF15348.6 KLO05482.1 - 8.9 6.5 24.3 0.058 13.7 5.7 2.5 3 0 0 3 3 3 0 Gemini of Cajal bodies-associated protein 8 Plavaka PF18759.1 KLO05486.1 - 9.7e-71 238.6 0.0 1.7e-70 237.8 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase AAA PF00004.29 KLO05487.1 - 2.4e-85 283.6 0.0 1.8e-46 157.9 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KLO05487.1 - 7.3e-15 55.1 0.0 1.3e-05 25.0 0.0 3.7 4 1 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_N PF02359.18 KLO05487.1 - 3.8e-14 52.6 0.2 1.4e-13 50.8 0.2 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 KLO05487.1 - 1.2e-11 45.0 0.0 2.9e-05 24.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KLO05487.1 - 3.4e-11 43.5 0.0 3e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KLO05487.1 - 5.3e-11 43.2 0.0 0.00047 20.6 0.0 3.9 2 2 1 3 3 3 2 AAA ATPase domain CDC48_2 PF02933.17 KLO05487.1 - 5.6e-11 42.1 0.0 1.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 KLO05487.1 - 1.2e-10 41.5 0.1 0.00091 19.2 0.0 4.4 2 2 1 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KLO05487.1 - 1.1e-09 38.7 0.0 0.0066 16.7 0.0 4.0 2 2 1 3 3 2 2 AAA domain TIP49 PF06068.13 KLO05487.1 - 3e-09 36.6 0.0 0.0013 18.1 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 KLO05487.1 - 6.6e-08 33.2 0.0 0.016 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KLO05487.1 - 9.7e-08 31.7 0.1 9.7e-08 31.7 0.1 3.2 3 1 0 3 3 2 1 AAA+ lid domain IstB_IS21 PF01695.17 KLO05487.1 - 1.9e-07 31.0 0.0 0.019 14.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KLO05487.1 - 5.8e-07 29.9 0.0 0.016 15.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KLO05487.1 - 1.1e-06 28.7 0.0 0.0064 16.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KLO05487.1 - 1.1e-06 28.2 0.2 0.023 14.1 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KLO05487.1 - 1.3e-06 28.0 0.2 0.14 11.5 0.1 3.3 3 0 0 3 3 3 2 KaiC AAA_28 PF13521.6 KLO05487.1 - 3.5e-06 27.4 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KLO05487.1 - 4.3e-06 26.4 0.0 0.016 14.7 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KLO05487.1 - 4.3e-06 26.6 0.0 0.082 12.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 KLO05487.1 - 5.9e-06 25.6 0.1 0.0082 15.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KLO05487.1 - 9.3e-06 25.4 0.0 0.3 10.8 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain ResIII PF04851.15 KLO05487.1 - 3.2e-05 24.0 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KLO05487.1 - 3.4e-05 24.4 0.0 0.11 13.0 0.0 3.1 2 1 0 2 2 2 1 ABC transporter DUF2075 PF09848.9 KLO05487.1 - 5.5e-05 22.6 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KLO05487.1 - 7.9e-05 22.2 0.3 0.39 10.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_17 PF13207.6 KLO05487.1 - 0.00013 22.4 0.0 0.53 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KLO05487.1 - 0.0002 21.2 0.0 0.75 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KLO05487.1 - 0.00023 21.1 0.0 0.79 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KLO05487.1 - 0.00034 20.6 0.0 0.26 11.3 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KLO05487.1 - 0.00044 19.5 0.0 0.027 13.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 KLO05487.1 - 0.00066 19.3 2.4 1 8.9 0.1 3.7 2 2 1 4 4 4 1 AAA domain Viral_helicase1 PF01443.18 KLO05487.1 - 0.00072 19.4 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KLO05487.1 - 0.00085 19.7 1.2 2.9 8.2 0.0 3.4 3 1 1 4 4 3 1 AAA domain AAA_30 PF13604.6 KLO05487.1 - 0.001 18.9 0.3 1.7 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KLO05487.1 - 0.001 19.0 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 KLO05487.1 - 0.0013 18.8 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 KLO05487.1 - 0.0018 17.5 0.0 0.52 9.4 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain NACHT PF05729.12 KLO05487.1 - 0.002 18.1 0.1 0.94 9.4 0.0 2.8 2 1 0 2 2 2 1 NACHT domain Bac_DnaA PF00308.18 KLO05487.1 - 0.0021 18.0 0.0 0.92 9.3 0.0 2.7 2 0 0 2 2 2 1 Bacterial dnaA protein UFD1 PF03152.14 KLO05487.1 - 0.0062 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 T2SSE PF00437.20 KLO05487.1 - 0.0064 15.6 0.0 0.64 9.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 KLO05487.1 - 0.0066 15.7 0.0 1.9 7.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.15 KLO05487.1 - 0.0082 16.1 0.2 3.3 7.6 0.0 3.3 3 0 0 3 3 3 1 NTPase IPT PF01745.16 KLO05487.1 - 0.0082 15.6 0.1 0.5 9.7 0.0 2.2 2 0 0 2 2 2 1 Isopentenyl transferase Cytidylate_kin PF02224.18 KLO05487.1 - 0.019 14.7 0.0 6.6 6.4 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase Rad17 PF03215.15 KLO05487.1 - 0.13 12.2 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 KLO05487.1 - 0.15 11.8 0.1 26 4.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_6 PF12774.7 KLO05487.1 - 0.21 10.5 0.1 7 5.5 0.0 2.2 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Cyclin_N PF00134.23 KLO05488.1 - 5.9e-08 32.5 0.0 8.6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KLO05488.1 - 0.0019 18.6 0.0 0.0027 18.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin Pkinase_fungal PF17667.1 KLO05489.1 - 2.8e-71 240.5 5.0 1.9e-47 161.9 0.0 2.5 2 1 1 3 3 3 2 Fungal protein kinase Kdo PF06293.14 KLO05489.1 - 1.9e-06 27.4 0.0 8.9e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KLO05489.1 - 0.00012 21.6 0.0 0.0005 19.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05489.1 - 0.1 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.23 KLO05489.1 - 0.1 12.5 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family BST2 PF16716.5 KLO05489.1 - 0.28 11.8 2.4 0.6 10.7 2.4 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Atg14 PF10186.9 KLO05489.1 - 5.8 5.9 9.1 8.4 5.4 8.5 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SesA PF17107.5 KLO05490.1 - 0.042 14.0 0.7 8.8 6.5 0.0 2.8 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases COesterase PF00135.28 KLO05491.1 - 5.5e-74 249.9 0.0 6.3e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO05491.1 - 2.4e-05 24.3 0.0 5.6e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold F-box PF00646.33 KLO05493.1 - 0.00025 20.8 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KLO05493.1 - 0.0042 17.0 0.1 0.0052 16.7 0.1 1.2 1 0 0 1 1 1 1 F-box MIS13 PF08202.11 KLO05495.1 - 9.4e-25 87.5 5.7 1.2e-24 87.1 3.4 2.1 2 0 0 2 2 2 1 Mis12-Mtw1 protein family DIOX_N PF14226.6 KLO05496.1 - 2.3e-13 50.9 0.0 4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO05496.1 - 4.9e-13 49.4 0.0 1.3e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily C2 PF00168.30 KLO05497.1 - 7.8e-15 55.0 0.1 1.2e-14 54.4 0.1 1.3 1 0 0 1 1 1 1 C2 domain Rod-binding PF10135.9 KLO05497.1 - 0.16 12.6 1.1 0.83 10.3 1.0 2.4 1 1 1 2 2 2 0 Rod binding protein K_channel_TID PF07941.11 KLO05497.1 - 1.2 9.6 5.2 2.7 8.5 5.2 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain CCDC50_N PF15295.6 KLO05497.1 - 3.9 7.7 14.2 14 5.9 6.5 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus F-box PF00646.33 KLO05498.1 - 0.00084 19.1 0.0 0.0026 17.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KLO05498.1 - 0.075 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 F-box JIP_LZII PF16471.5 KLO05498.1 - 0.097 12.9 0.9 0.46 10.7 0.0 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Cellulase PF00150.18 KLO05501.1 - 1.1e-25 90.7 5.4 1.5e-25 90.2 5.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KLO05501.1 - 3.5e-11 42.9 4.4 9.4e-11 41.5 4.4 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_44 PF12891.7 KLO05501.1 - 0.00022 21.2 0.0 0.00049 20.1 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 44 Glyco_hydro_2_C PF02836.17 KLO05501.1 - 0.0027 16.9 0.0 0.0059 15.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ring_hydroxyl_A PF00848.19 KLO05502.1 - 3.2e-25 89.4 1.7 7.1e-22 78.4 1.3 2.5 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KLO05502.1 - 3.7e-13 49.2 0.0 7.4e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pkinase_Tyr PF07714.17 KLO05503.1 - 7.8e-42 143.3 0.0 1.2e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO05503.1 - 5.4e-36 124.3 0.0 1e-35 123.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO05503.1 - 3.6e-05 23.8 0.1 9.4e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KLO05503.1 - 0.0064 15.5 0.0 0.02 13.9 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain DUF4238 PF14022.6 KLO05503.1 - 0.0088 15.6 0.0 0.017 14.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4238) Fructosamin_kin PF03881.14 KLO05503.1 - 0.03 13.5 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase TMEM154 PF15102.6 KLO05504.1 - 0.0046 16.9 2.6 0.054 13.4 0.0 2.2 2 0 0 2 2 2 1 TMEM154 protein family Amnionless PF14828.6 KLO05504.1 - 0.026 13.4 0.1 0.039 12.8 0.1 1.2 1 0 0 1 1 1 0 Amnionless Orf78 PF06024.12 KLO05504.1 - 0.029 14.7 0.0 0.056 13.8 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF347 PF03988.12 KLO05504.1 - 0.075 13.2 2.7 0.15 12.2 0.1 2.3 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Trp_oprn_chp PF09534.10 KLO05504.1 - 0.089 12.6 3.6 0.11 12.3 0.2 2.0 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Iso_dh PF00180.20 KLO05505.1 - 1.7e-75 254.3 0.0 2.1e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-C2H2 PF00096.26 KLO05510.1 - 2.3e-09 37.2 8.0 0.0064 16.9 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO05510.1 - 3e-06 27.6 8.7 0.062 14.2 0.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KLO05510.1 - 0.006 16.9 0.4 4.6 7.8 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KLO05510.1 - 0.0069 16.1 0.3 0.4 10.5 0.1 2.6 2 0 0 2 2 2 1 zinc-finger C2H2-type DUF2089 PF09862.9 KLO05510.1 - 0.084 12.9 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) FOXP-CC PF16159.5 KLO05510.1 - 0.13 12.9 1.4 2.6 8.7 0.3 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KLO05510.1 - 0.16 12.4 12.0 3.6 8.2 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KLO05510.1 - 0.83 10.0 4.9 15 6.0 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KLO05510.1 - 7.9 6.6 6.1 2.7 8.1 1.2 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger WD40 PF00400.32 KLO05511.1 - 9.6e-55 181.3 36.7 1.1e-08 35.5 2.5 8.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO05511.1 - 1.9e-23 82.5 0.1 0.0091 16.3 0.0 7.4 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 KLO05511.1 - 1.7e-12 47.8 0.0 5.2e-06 26.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KLO05511.1 - 2.4e-10 41.1 0.0 0.00072 20.0 0.0 3.1 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KLO05511.1 - 5.3e-10 39.5 0.0 7.3e-05 22.7 0.0 3.5 3 2 0 3 3 2 2 NACHT domain NB-ARC PF00931.22 KLO05511.1 - 2.1e-09 37.0 0.0 2.5e-06 26.9 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain AAA PF00004.29 KLO05511.1 - 6.6e-09 36.3 0.0 0.0035 17.8 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KLO05511.1 - 1.9e-07 30.6 0.0 0.0087 15.4 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.6 KLO05511.1 - 5.4e-07 30.2 0.0 0.033 14.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain APS_kinase PF01583.20 KLO05511.1 - 2.1e-06 27.7 0.0 0.04 13.8 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase RNA_helicase PF00910.22 KLO05511.1 - 2.5e-06 27.8 0.0 0.13 12.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Ge1_WD40 PF16529.5 KLO05511.1 - 1.2e-05 24.5 3.5 1.8 7.4 0.0 5.5 1 1 4 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KLO05511.1 - 1.4e-05 24.6 2.0 0.081 12.2 0.0 3.9 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF2075 PF09848.9 KLO05511.1 - 5.1e-05 22.7 0.0 0.21 10.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KLO05511.1 - 0.00014 22.0 0.0 0.25 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KLO05511.1 - 0.00039 20.7 0.0 0.31 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain PD40 PF07676.12 KLO05511.1 - 0.0006 19.7 1.3 12 6.0 0.0 5.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat AAA_25 PF13481.6 KLO05511.1 - 0.00064 19.4 0.9 0.78 9.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain RuvB_N PF05496.12 KLO05511.1 - 0.00074 19.3 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KLO05511.1 - 0.0012 18.8 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain WD40_like PF17005.5 KLO05511.1 - 0.0018 17.7 0.0 14 4.9 0.0 4.2 4 1 0 4 4 4 0 WD40-like domain IstB_IS21 PF01695.17 KLO05511.1 - 0.0031 17.3 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KLO05511.1 - 0.0039 16.9 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KLO05511.1 - 0.006 16.5 0.0 0.11 12.5 0.0 2.6 3 0 0 3 3 2 1 NTPase ABC_tran PF00005.27 KLO05511.1 - 0.0063 17.0 0.0 2.2 8.8 0.0 2.7 2 0 0 2 2 2 1 ABC transporter TIP49 PF06068.13 KLO05511.1 - 0.008 15.4 0.0 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_19 PF13245.6 KLO05511.1 - 0.011 16.1 0.0 0.22 11.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KLO05511.1 - 0.011 16.1 0.1 1 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KLO05511.1 - 0.012 15.6 0.0 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 KLO05511.1 - 0.015 15.1 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KLO05511.1 - 0.019 14.7 0.0 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Frtz PF11768.8 KLO05511.1 - 0.043 12.1 0.0 0.26 9.5 0.0 2.1 2 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Torsin PF06309.11 KLO05511.1 - 0.048 13.8 0.0 16 5.6 0.0 2.7 2 0 0 2 2 2 0 Torsin KTI12 PF08433.10 KLO05511.1 - 0.063 12.7 0.0 2.5 7.5 0.0 2.5 3 0 0 3 3 2 0 Chromatin associated protein KTI12 ResIII PF04851.15 KLO05511.1 - 0.065 13.2 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CbiA PF01656.23 KLO05511.1 - 0.07 13.2 0.2 2.6 8.1 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.6 KLO05511.1 - 0.075 13.1 0.0 22 5.1 0.0 3.4 3 1 0 3 3 2 0 AAA domain Parvo_NS1 PF01057.17 KLO05511.1 - 0.084 12.0 0.0 4 6.4 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 MeaB PF03308.16 KLO05511.1 - 0.09 11.7 0.0 2.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 KLO05511.1 - 0.1 12.5 0.0 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KLO05511.1 - 0.11 12.5 0.0 10 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 KLO05511.1 - 0.15 11.7 0.1 0.7 9.5 0.0 2.1 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain ADK PF00406.22 KLO05511.1 - 0.17 12.0 0.1 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Adenylate kinase Mg_chelatase PF01078.21 KLO05511.1 - 0.17 11.3 0.0 23 4.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.14 KLO05511.1 - 0.4 9.9 2.7 19 4.3 0.1 3.5 4 0 0 4 4 4 0 KAP family P-loop domain Oxidored_FMN PF00724.20 KLO05514.1 - 5.4e-10 39.1 0.0 6.3e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Abhydrolase_3 PF07859.13 KLO05515.1 - 2.2e-28 99.6 0.0 3.8e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO05515.1 - 1.7e-15 56.8 0.0 3.8e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KLO05515.1 - 0.0015 19.2 0.9 0.0015 19.2 0.9 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KLO05515.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2920 PF11144.8 KLO05515.1 - 0.34 10.0 0.3 13 4.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 KLO05516.1 - 4.7e-27 95.2 0.0 6.7e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO05516.1 - 2.2e-13 49.8 0.0 9.3e-12 44.5 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KLO05516.1 - 0.21 11.0 0.2 0.37 10.2 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KLO05516.1 - 1.7 9.2 6.7 0.16 12.5 0.6 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF2569 PF10754.9 KLO05517.1 - 0.66 10.4 4.0 2.1 8.8 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2569) FAD_binding_3 PF01494.19 KLO05518.1 - 1.5e-14 54.0 0.0 8.8e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KLO05518.1 - 6.5e-09 35.4 0.1 2e-05 24.0 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KLO05518.1 - 4e-08 32.8 0.2 6.3e-08 32.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KLO05518.1 - 4.2e-08 33.2 0.9 2e-05 24.3 0.2 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KLO05518.1 - 4.7e-08 32.6 0.0 2e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO05518.1 - 8.6e-07 29.1 0.1 2.4e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KLO05518.1 - 1.6e-06 27.1 0.4 1.3e-05 24.1 0.4 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KLO05518.1 - 0.00038 19.9 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KLO05518.1 - 0.00064 20.2 0.4 0.0028 18.2 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KLO05518.1 - 0.00074 18.5 0.4 0.19 10.5 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 KLO05518.1 - 0.00088 18.5 0.2 0.0012 18.0 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KLO05518.1 - 0.012 14.7 0.3 0.038 13.0 0.3 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KLO05518.1 - 0.016 14.5 0.1 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KLO05518.1 - 0.031 13.6 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KLO05518.1 - 0.045 13.3 0.2 0.07 12.7 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.24 KLO05518.1 - 0.12 11.6 0.0 0.79 8.9 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Abhydrolase_3 PF07859.13 KLO05519.1 - 1.4e-24 87.1 0.0 2.2e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO05519.1 - 9.8e-17 60.9 0.0 1.8e-16 60.0 0.0 1.3 2 0 0 2 2 2 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KLO05519.1 - 0.0004 21.0 0.0 0.002 18.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family BTB PF00651.31 KLO05520.1 - 0.00011 22.3 1.0 0.00062 20.0 1.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain Pkinase_Tyr PF07714.17 KLO05521.1 - 3.4e-34 118.3 0.0 6.1e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO05521.1 - 1.6e-33 116.2 0.0 6.5e-33 114.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KLO05521.1 - 0.014 15.4 0.0 0.051 13.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family ANAPC4 PF12896.7 KLO05521.1 - 0.027 13.9 4.2 0.051 13.1 1.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 ZapD PF07072.11 KLO05521.1 - 0.1 12.3 1.3 0.26 11.0 1.3 1.6 1 1 0 1 1 1 0 Cell division protein Abhydrolase_3 PF07859.13 KLO05523.1 - 4.3e-26 92.1 0.0 6.2e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO05523.1 - 9.8e-17 60.9 0.0 1e-14 54.3 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KLO05523.1 - 0.03 14.9 2.9 0.034 14.7 0.8 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family FapA PF03961.13 KLO05524.1 - 0.91 8.1 5.1 0.99 7.9 5.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ACC_epsilon PF13822.6 KLO05524.1 - 1.5 9.6 4.1 0.81 10.4 1.0 2.0 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit BAR_2 PF10455.9 KLO05525.1 - 0.09 11.9 1.3 0.12 11.5 1.3 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking XhlA PF10779.9 KLO05525.1 - 0.82 9.9 2.5 1.4 9.1 2.5 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Glyco_hydro_18 PF00704.28 KLO05526.1 - 1e-35 124.0 0.5 1.9e-35 123.1 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KLO05526.1 - 7.7e-12 45.5 13.2 2.3e-11 44.0 13.2 1.9 1 0 0 1 1 1 1 Chitin recognition protein LysM PF01476.20 KLO05526.1 - 7.7e-10 38.7 0.3 0.00016 21.6 0.0 2.7 2 0 0 2 2 2 2 LysM domain DUF2092 PF09865.9 KLO05526.1 - 0.12 11.7 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) Alpha-amylase PF00128.24 KLO05527.1 - 0.24 10.9 0.4 0.3 10.6 0.4 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Spc7 PF08317.11 KLO05528.1 - 0.00018 20.5 10.0 0.00021 20.3 10.0 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF948 PF06103.11 KLO05528.1 - 0.0022 18.2 5.1 1.7 9.0 3.2 3.0 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) TMF_TATA_bd PF12325.8 KLO05528.1 - 0.0044 17.2 7.1 0.0044 17.2 7.1 2.2 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.8 KLO05528.1 - 0.019 15.1 7.5 0.23 11.6 1.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) FlxA PF14282.6 KLO05528.1 - 0.019 14.9 10.4 0.063 13.3 9.4 2.0 1 1 1 2 2 2 0 FlxA-like protein CLZ PF16526.5 KLO05528.1 - 0.03 14.7 15.1 2.1 8.7 0.6 3.2 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SseC PF04888.12 KLO05528.1 - 0.034 13.8 4.6 0.043 13.4 4.6 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family HMMR_C PF15908.5 KLO05528.1 - 0.045 14.0 5.6 0.15 12.3 5.5 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Atg14 PF10186.9 KLO05528.1 - 0.046 12.8 12.0 0.065 12.3 12.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 KLO05528.1 - 0.056 13.8 6.2 21 5.6 0.0 3.6 3 1 2 5 5 5 0 Lipoprotein leucine-zipper CENP-H PF05837.12 KLO05528.1 - 0.061 13.7 15.3 0.48 10.8 3.7 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 KLO05528.1 - 0.068 13.4 10.3 0.54 10.4 2.4 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CLP_protease PF00574.23 KLO05528.1 - 0.069 13.0 4.7 1.1 9.2 0.7 2.2 1 1 1 2 2 2 0 Clp protease V_ATPase_I PF01496.19 KLO05528.1 - 0.1 10.5 8.0 0.12 10.3 8.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.6 KLO05528.1 - 0.1 11.2 6.8 0.13 10.9 6.8 1.1 1 0 0 1 1 1 0 AAA domain Fez1 PF06818.15 KLO05528.1 - 0.11 13.0 11.8 0.16 12.4 11.8 1.3 1 0 0 1 1 1 0 Fez1 DivIC PF04977.15 KLO05528.1 - 0.11 12.3 11.0 0.94 9.3 1.7 3.1 1 1 2 3 3 3 0 Septum formation initiator PMC2NT PF08066.12 KLO05528.1 - 0.11 13.2 6.9 0.085 13.6 2.6 2.2 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DUF773 PF05600.12 KLO05528.1 - 0.12 11.1 8.6 0.11 11.2 7.9 1.2 1 1 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 COG5 PF10392.9 KLO05528.1 - 0.14 12.4 10.0 0.34 11.1 7.5 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 OmpH PF03938.14 KLO05528.1 - 0.14 12.5 10.0 0.3 11.4 10.0 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ADIP PF11559.8 KLO05528.1 - 0.14 12.2 19.0 0.73 9.9 1.9 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.12 KLO05528.1 - 0.15 12.0 6.7 0.14 12.2 4.1 1.9 1 1 1 2 2 2 0 Laminin Domain II Tektin PF03148.14 KLO05528.1 - 0.15 10.7 17.8 0.099 11.4 4.8 2.1 1 1 1 2 2 2 0 Tektin family Uteroglobin PF01099.17 KLO05528.1 - 0.19 12.1 2.4 1.2 9.5 1.7 2.0 1 1 1 2 2 2 0 Uteroglobin family TPR_MLP1_2 PF07926.12 KLO05528.1 - 0.2 11.7 15.4 1.4 9.0 14.6 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phage_HK97_TLTM PF06120.11 KLO05528.1 - 0.23 10.6 6.9 0.35 10.0 6.9 1.3 1 1 0 1 1 1 0 Tail length tape measure protein YabA PF06156.13 KLO05528.1 - 0.25 12.0 8.3 36 5.0 8.3 2.4 1 1 0 1 1 1 0 Initiation control protein YabA ISG65-75 PF11727.8 KLO05528.1 - 0.27 10.5 8.7 1.3 8.1 0.5 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein Med9 PF07544.13 KLO05528.1 - 0.27 11.4 7.4 0.24 11.5 5.3 1.9 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Pup PF05639.11 KLO05528.1 - 0.31 12.0 10.2 0.47 11.4 4.2 2.9 2 1 1 3 3 3 0 Pup-like protein Csm1_N PF18504.1 KLO05528.1 - 0.42 11.0 9.1 0.3 11.4 1.9 3.0 1 1 2 3 3 3 0 Csm1 N-terminal domain KxDL PF10241.9 KLO05528.1 - 0.43 10.9 8.0 0.12 12.6 3.4 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein IFT46_B_C PF12317.8 KLO05528.1 - 0.45 10.2 5.0 0.83 9.3 5.0 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal SlyX PF04102.12 KLO05528.1 - 0.5 11.0 13.8 1.5 9.5 2.3 3.4 1 1 1 3 3 3 0 SlyX DHR10 PF18595.1 KLO05528.1 - 0.52 10.4 19.0 1.2 9.2 9.1 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Prominin PF05478.11 KLO05528.1 - 0.58 8.0 3.4 0.65 7.9 3.4 1.2 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 KLO05528.1 - 0.63 9.6 10.2 0.81 9.2 10.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 KLO05528.1 - 0.66 10.2 16.3 2.4 8.4 16.4 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 FapA PF03961.13 KLO05528.1 - 0.69 8.4 5.7 0.88 8.1 5.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A YtxH PF12732.7 KLO05528.1 - 1 9.9 2.9 1.1 9.8 0.8 2.0 1 1 1 2 2 2 0 YtxH-like protein Flagellin_N PF00669.20 KLO05528.1 - 1.3 9.1 7.8 0.12 12.5 1.3 2.2 3 0 0 3 3 2 0 Bacterial flagellin N-terminal helical region bZIP_1 PF00170.21 KLO05528.1 - 1.4 9.0 14.0 5.6 7.1 1.8 2.5 2 0 0 2 2 2 0 bZIP transcription factor GrpE PF01025.19 KLO05528.1 - 1.5 8.4 11.0 14 5.3 11.0 2.2 1 1 0 1 1 1 0 GrpE DUF16 PF01519.16 KLO05528.1 - 1.7 9.2 7.9 0.71 10.4 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 zf-C4H2 PF10146.9 KLO05528.1 - 2.2 8.5 13.5 3.3 8.0 11.5 1.8 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4349 PF14257.6 KLO05528.1 - 2.7 7.4 15.2 5.6 6.3 15.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) TMPIT PF07851.13 KLO05528.1 - 2.8 7.1 9.2 2.2 7.4 7.5 1.6 1 1 1 2 2 2 0 TMPIT-like protein DUF2203 PF09969.9 KLO05528.1 - 4.2 8.1 9.7 3.2 8.5 4.7 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CCT_2 PF09425.10 KLO05528.1 - 4.7 7.2 6.5 25 4.9 2.0 2.5 1 1 1 2 2 2 0 Divergent CCT motif HIP1_clath_bdg PF16515.5 KLO05528.1 - 4.8 7.9 16.8 2.5 8.8 10.3 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TolA_bind_tri PF16331.5 KLO05528.1 - 4.8 7.3 14.4 11 6.2 2.5 2.9 1 1 2 3 3 3 0 TolA binding protein trimerisation DUF1664 PF07889.12 KLO05528.1 - 5.8 7.0 10.8 7.2 6.7 7.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KLO05528.1 - 6.2 7.3 7.0 8.1 6.9 1.2 3.0 2 1 3 5 5 3 0 Flagella accessory protein C (FlaC) dCache_2 PF08269.11 KLO05528.1 - 6.3 5.9 6.7 1.4 8.1 3.5 1.5 2 0 0 2 2 2 0 Cache domain FUSC PF04632.12 KLO05528.1 - 6.6 5.1 9.1 8.7 4.7 9.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_GPO PF05929.11 KLO05528.1 - 7 6.2 11.5 2.2 7.8 7.0 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase BLOC1_2 PF10046.9 KLO05528.1 - 7.1 7.0 10.8 44 4.5 7.9 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 KLO05528.1 - 7.1 6.9 10.6 0.98 9.7 1.8 3.0 1 1 2 3 3 3 0 Haemolysin XhlA BRE1 PF08647.11 KLO05528.1 - 7.5 6.7 14.4 13 6.0 9.2 2.3 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 KLO05528.1 - 7.6 6.6 15.7 7.9 6.5 13.8 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PCRF PF03462.18 KLO05528.1 - 8.3 6.2 11.0 5.1 6.9 8.4 1.7 1 1 1 2 2 2 0 PCRF domain BST2 PF16716.5 KLO05528.1 - 9.4 6.9 13.0 2.4 8.8 3.2 2.9 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 GRDP-like PF07173.12 KLO05529.1 - 0.11 13.1 2.1 0.13 12.9 2.1 1.1 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like Sigma_1_2 PF03084.14 KLO05529.1 - 0.19 11.0 0.9 0.22 10.8 0.9 1.0 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family Ribosomal_L31e PF01198.19 KLO05530.1 - 0.17 12.1 0.0 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L31e PucR PF07905.11 KLO05531.1 - 0.0084 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family Ribosomal_L5_C PF00673.21 KLO05532.1 - 1.5e-27 95.6 0.0 2.2e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus DUF4436 PF14494.6 KLO05534.1 - 6.9e-07 28.8 2.5 0.00011 21.7 2.5 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4436) SfLAP PF11139.8 KLO05534.1 - 0.0071 15.8 2.4 0.0071 15.8 2.4 2.1 2 0 0 2 2 2 1 Sap, sulfolipid-1-addressing protein FAD_binding_4 PF01565.23 KLO05539.1 - 1.1e-19 70.5 0.4 2.6e-19 69.3 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KLO05539.1 - 2.9e-07 30.5 0.0 6.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_M64 PF09471.10 KLO05540.1 - 1.5e-26 93.5 0.0 2.8e-26 92.6 0.0 1.4 1 1 0 1 1 1 1 IgA Peptidase M64 MRP-L47 PF06984.13 KLO05541.1 - 1e-20 73.6 0.8 2.3e-20 72.5 0.8 1.6 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) MscS_TM PF12794.7 KLO05541.1 - 0.7 8.7 5.6 0.093 11.6 1.3 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Complex1_LYR PF05347.15 KLO05542.1 - 0.0061 16.6 0.2 0.0083 16.2 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Pkinase_fungal PF17667.1 KLO05544.1 - 3.4e-32 111.8 0.0 7.4e-27 94.2 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase Pkinase_fungal PF17667.1 KLO05545.1 - 3.7e-32 111.6 0.4 4.2e-32 111.4 0.4 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO05545.1 - 3.1e-10 39.9 0.0 3.1e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05545.1 - 1.5e-05 24.4 0.0 1.8e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KLO05545.1 - 0.00036 20.0 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO05545.1 - 0.0034 17.3 0.0 0.0049 16.8 0.0 1.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Plavaka PF18759.1 KLO05546.1 - 4e-66 223.5 0.0 7.2e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase F-box-like PF12937.7 KLO05550.1 - 5.9e-10 38.9 1.1 2.3e-09 37.0 1.1 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05550.1 - 0.81 9.6 4.9 5.5 7.0 0.3 3.0 3 0 0 3 3 3 0 F-box domain SKG6 PF08693.10 KLO05554.1 - 4.9 6.6 8.2 0.2 11.1 2.0 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Sorb PF02208.16 KLO05562.1 - 2.2 8.2 6.0 1.8 8.4 0.3 2.8 3 0 0 3 3 3 0 Sorbin homologous domain KOW PF00467.29 KLO05564.1 - 1.6e-11 43.8 11.8 0.0085 16.0 0.1 6.3 6 0 0 6 6 6 5 KOW motif DUF3912 PF13051.6 KLO05564.1 - 1.2e-06 28.6 0.3 0.0019 18.4 0.0 4.4 5 0 0 5 5 5 1 Protein of unknown function (DUF3912) Spt5-NGN PF03439.13 KLO05564.1 - 0.045 13.6 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section KDZ PF18758.1 KLO05566.1 - 2.8e-50 171.0 2.4 5.7e-50 170.0 2.4 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO05566.1 - 1.1e-23 83.5 0.1 2.3e-23 82.4 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KLO05566.1 - 0.16 11.8 2.3 0.57 10.0 0.0 2.6 2 1 1 3 3 3 0 CxC3 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KLO05566.1 - 0.2 11.8 3.3 0.52 10.5 3.3 1.7 1 0 0 1 1 1 0 B-box zinc finger zf-MYND PF01753.18 KLO05568.1 - 2.8e-06 27.3 17.0 8.7e-06 25.7 17.0 1.9 1 0 0 1 1 1 1 MYND finger HTH_Tnp_Tc5 PF03221.16 KLO05570.1 - 6.1e-13 48.6 0.0 2.1e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KLO05570.1 - 3.8e-05 23.2 0.7 8.6e-05 22.1 0.7 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 KLO05570.1 - 0.0013 18.7 0.1 0.004 17.2 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix F-box-like PF12937.7 KLO05570.1 - 0.0021 17.9 0.2 0.0052 16.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like HTH_psq PF05225.16 KLO05570.1 - 0.0043 16.7 0.0 0.62 9.8 0.0 2.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_36 PF13730.6 KLO05570.1 - 0.019 14.9 0.1 0.049 13.6 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain TnsD PF15978.5 KLO05570.1 - 0.02 13.9 0.6 0.028 13.4 0.6 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_Tnp_4 PF13613.6 KLO05570.1 - 0.021 14.5 0.0 0.099 12.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_38 PF13936.6 KLO05570.1 - 0.042 13.6 0.4 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 KLO05570.1 - 0.055 13.3 0.1 0.21 11.4 0.0 2.0 2 0 0 2 2 1 0 Homeodomain-like domain MarR PF01047.22 KLO05570.1 - 0.076 13.0 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_29 PF13551.6 KLO05570.1 - 0.094 12.8 0.0 4.9 7.2 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn helix MarR_2 PF12802.7 KLO05570.1 - 0.11 12.3 0.1 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 MarR family HTH_28 PF13518.6 KLO05570.1 - 0.12 12.6 0.0 0.92 9.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Hen1_L PF12623.7 KLO05570.1 - 0.12 11.4 0.0 0.28 10.2 0.0 1.6 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 DUF937 PF06078.11 KLO05570.1 - 0.13 12.9 0.0 3.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) HTH_Crp_2 PF13545.6 KLO05570.1 - 0.13 12.2 0.1 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Skp1_POZ PF03931.15 KLO05571.1 - 1.3e-13 50.9 0.1 2.2e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 KLO05571.1 - 6.1e-12 45.5 1.4 1.4e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 Skp1 family, dimerisation domain L31 PF09784.9 KLO05573.1 - 0.12 12.8 0.1 0.4 11.1 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 TPR_10 PF13374.6 KLO05578.1 - 1.9e-24 84.8 18.9 0.00018 21.2 0.0 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 KLO05578.1 - 3.4e-15 56.1 15.5 0.0005 20.3 0.2 7.4 5 3 1 6 6 6 4 Tetratricopeptide repeat ANAPC5 PF12862.7 KLO05578.1 - 1.6e-12 47.3 19.4 0.35 11.0 0.2 8.4 1 1 7 8 8 8 4 Anaphase-promoting complex subunit 5 TPR_8 PF13181.6 KLO05578.1 - 5.5e-12 44.9 0.7 0.76 10.1 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat AAA_16 PF13191.6 KLO05578.1 - 1.7e-10 41.5 1.3 8.1e-10 39.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain TPR_2 PF07719.17 KLO05578.1 - 1.1e-05 25.2 0.1 55 4.2 0.0 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF3856 PF12968.7 KLO05578.1 - 1.8e-05 24.8 12.2 0.015 15.4 0.7 3.7 1 1 1 3 3 3 3 Domain of Unknown Function (DUF3856) NACHT PF05729.12 KLO05578.1 - 2.9e-05 24.1 0.0 7.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 KLO05578.1 - 0.0011 19.5 0.0 0.0054 17.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KLO05578.1 - 0.0012 18.8 0.0 0.0075 16.2 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA PF00004.29 KLO05578.1 - 0.0014 19.1 0.0 0.0045 17.4 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KLO05578.1 - 0.0032 17.2 0.1 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain TPR_1 PF00515.28 KLO05578.1 - 0.0079 16.0 0.1 24 5.0 0.0 5.2 7 0 0 7 7 6 0 Tetratricopeptide repeat AAA_5 PF07728.14 KLO05578.1 - 0.012 15.6 0.0 0.041 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HEPN-like_int PF18867.1 KLO05578.1 - 0.015 15.2 0.0 0.045 13.6 0.0 1.8 1 0 0 1 1 1 0 HEPN-like integron domain AAA_19 PF13245.6 KLO05578.1 - 0.018 15.4 0.0 0.061 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KLO05578.1 - 0.019 14.7 0.0 0.052 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KLO05578.1 - 0.031 14.5 0.9 0.059 13.6 0.2 1.9 2 0 0 2 2 1 0 AAA domain TPR_7 PF13176.6 KLO05578.1 - 0.057 13.5 1.7 3e+02 1.8 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 KLO05578.1 - 0.067 13.5 0.0 0.34 11.2 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KLO05578.1 - 0.12 12.0 0.1 1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KLO05578.1 - 0.12 11.8 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 VPS11_C PF12451.8 KLO05578.1 - 0.13 12.6 0.6 10 6.4 0.0 3.8 4 0 0 4 4 2 0 Vacuolar protein sorting protein 11 C terminal DUF1664 PF07889.12 KLO05578.1 - 0.63 10.1 4.3 8.2 6.5 0.6 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Phage-MuB_C PF09077.11 KLO05578.1 - 1.2 9.1 9.1 3.2 7.7 0.1 4.7 3 2 3 6 6 5 0 Mu B transposition protein, C terminal DUF2783 PF10932.8 KLO05578.1 - 4.7 7.0 12.0 2.8 7.7 0.1 5.0 3 1 2 5 5 5 0 Protein of unknown function (DUF2783) zf-CCHC_3 PF13917.6 KLO05579.1 - 5.8e-21 74.2 2.7 9e-21 73.6 2.7 1.3 1 0 0 1 1 1 1 Zinc knuckle HATPase_c PF02518.26 KLO05580.1 - 3.5e-23 82.3 0.0 7.3e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KLO05580.1 - 2.3e-17 63.2 0.0 6.3e-16 58.5 0.0 2.5 1 1 0 1 1 1 1 Response regulator receiver domain PHY PF00360.20 KLO05580.1 - 1e-13 51.0 0.0 1.8e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region GAF PF01590.26 KLO05580.1 - 1.3e-12 48.4 0.0 4.4e-12 46.8 0.0 2.0 1 0 0 1 1 1 1 GAF domain PAS_2 PF08446.11 KLO05580.1 - 2.3e-09 37.9 0.0 6.7e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 KLO05580.1 - 1.7e-08 34.4 2.0 5.2e-08 32.8 2.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KLO05580.1 - 0.064 13.1 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OKR_DC_1_N PF03709.15 KLO05580.1 - 0.12 12.6 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Iwr1 PF08574.10 KLO05581.1 - 3.6e-14 53.5 9.5 3.6e-14 53.5 9.5 3.1 2 1 1 3 3 3 1 Transcription factor Iwr1 Abhydrolase_6 PF12697.7 KLO05582.1 - 7e-10 39.9 1.7 1.4e-09 38.9 1.7 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO05582.1 - 9.6e-10 38.1 0.1 2.5e-08 33.5 0.1 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KLO05582.1 - 1.3e-08 35.0 0.4 2.4e-08 34.1 0.4 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KLO05582.1 - 2.7e-06 27.2 0.1 7.2e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KLO05582.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.5 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.12 KLO05582.1 - 0.019 13.9 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Peptidase_S28 PF05577.12 KLO05582.1 - 0.024 13.4 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Ytp1 PF10355.9 KLO05583.1 - 1.8e-57 194.7 21.5 1.4e-55 188.4 21.5 2.3 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KLO05583.1 - 4.3e-24 84.3 3.3 4.3e-24 84.3 3.3 3.1 4 0 0 4 4 4 2 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KLO05583.1 - 0.00067 19.8 3.5 0.00067 19.8 3.5 4.1 3 2 1 4 4 4 1 Eukaryotic cytochrome b561 MWFE PF15879.5 KLO05583.1 - 0.026 14.7 3.4 2.2 8.5 0.0 3.8 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase MWFE subunit RPT PF13446.6 KLO05584.1 - 9.3e-05 22.3 0.0 0.06 13.3 0.0 2.0 2 0 0 2 2 2 2 A repeated domain in UCH-protein AAA_7 PF12775.7 KLO05585.1 - 0.18 11.3 0.1 0.3 10.6 0.0 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region YvrJ PF12841.7 KLO05589.1 - 0.75 9.4 3.4 0.31 10.6 0.2 1.9 2 0 0 2 2 2 0 YvrJ protein family DUF3176 PF11374.8 KLO05590.1 - 0.003 17.7 1.3 0.011 16.0 1.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) MULE PF10551.9 KLO05591.1 - 4.4e-11 43.0 0.0 8.7e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FAM176 PF14851.6 KLO05591.1 - 3.7 7.2 8.4 0.23 11.1 1.8 2.2 2 0 0 2 2 2 0 FAM176 family RPN2_C PF18004.1 KLO05591.1 - 7.5 6.5 8.3 1.1 9.2 1.3 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain HTH_13 PF11972.8 KLO05592.1 - 0.06 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 HTH DNA binding domain Copper-bind PF00127.20 KLO05596.1 - 0.0022 18.4 0.0 0.005 17.3 0.0 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Csm1_N PF18504.1 KLO05597.1 - 0.01 16.1 5.5 0.02 15.2 5.5 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF2096 PF09869.9 KLO05598.1 - 0.021 14.9 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) LIF_OSM PF01291.17 KLO05598.1 - 0.022 14.9 0.2 0.57 10.3 0.1 2.4 2 0 0 2 2 2 0 LIF / OSM family Alanine_zipper PF11839.8 KLO05598.1 - 0.14 12.5 15.2 0.49 10.8 15.2 1.9 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein NUC194 PF08163.12 KLO05598.1 - 0.55 9.1 3.4 1 8.2 3.4 1.4 1 0 0 1 1 1 0 NUC194 domain SIKE PF05769.11 KLO05598.1 - 1.7 8.6 8.1 0.15 12.0 1.3 2.4 3 0 0 3 3 3 0 SIKE family TMEM214 PF10151.9 KLO05598.1 - 2.8 6.3 7.6 4.8 5.5 7.6 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Cast PF10174.9 KLO05601.1 - 0.0012 17.2 14.4 0.0054 15.0 13.9 1.9 1 1 1 2 2 2 1 RIM-binding protein of the cytomatrix active zone Atg14 PF10186.9 KLO05601.1 - 0.0015 17.7 8.0 0.0024 17.0 8.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 KLO05601.1 - 0.0024 17.9 15.0 0.02 14.9 3.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.19 KLO05601.1 - 0.0025 15.8 5.1 0.0034 15.4 5.1 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF2951 PF11166.8 KLO05601.1 - 0.0055 16.9 0.1 0.0055 16.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2951) Filament PF00038.21 KLO05601.1 - 0.0065 16.1 11.3 0.011 15.4 11.3 1.2 1 0 0 1 1 1 1 Intermediate filament protein Laminin_II PF06009.12 KLO05601.1 - 0.0077 16.3 1.8 0.0077 16.3 1.8 2.3 1 1 0 2 2 2 1 Laminin Domain II FPP PF05911.11 KLO05601.1 - 0.014 13.6 11.5 0.0098 14.1 8.7 1.8 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil FliJ PF02050.16 KLO05601.1 - 0.031 14.5 10.7 0.068 13.4 10.7 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein GAS PF13851.6 KLO05601.1 - 0.032 13.6 15.6 0.21 10.9 4.5 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ERM PF00769.19 KLO05601.1 - 0.037 13.8 16.7 0.07 12.9 16.7 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF812 PF05667.11 KLO05601.1 - 0.046 12.6 9.1 0.072 12.0 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 KLO05601.1 - 0.06 12.7 9.6 0.11 11.8 9.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 KLO05601.1 - 0.072 13.2 14.0 0.2 11.7 5.7 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 KLO05601.1 - 0.093 11.4 7.6 0.15 10.7 7.6 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 KLO05601.1 - 0.099 11.5 14.7 0.68 8.8 14.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.8 KLO05601.1 - 0.11 9.9 13.3 0.16 9.4 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ERO1 PF04137.15 KLO05601.1 - 0.13 11.4 2.4 0.25 10.5 2.4 1.5 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) TPR_MLP1_2 PF07926.12 KLO05601.1 - 0.14 12.2 16.7 0.36 10.9 1.7 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-K PF11802.8 KLO05601.1 - 0.16 11.5 8.6 0.29 10.7 8.6 1.4 1 0 0 1 1 1 0 Centromere-associated protein K ADIP PF11559.8 KLO05601.1 - 0.17 11.9 15.8 2.4 8.3 2.0 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 KLO05601.1 - 0.19 11.9 16.2 0.52 10.5 16.2 1.8 1 0 0 1 1 1 0 Tropomyosin like Tropomyosin PF00261.20 KLO05601.1 - 0.21 10.9 14.5 1 8.7 14.5 2.1 1 1 0 1 1 1 0 Tropomyosin YabA PF06156.13 KLO05601.1 - 0.35 11.5 8.2 0.22 12.2 1.0 2.9 1 1 0 2 2 2 0 Initiation control protein YabA KxDL PF10241.9 KLO05601.1 - 0.55 10.5 8.2 5.2 7.4 0.7 3.3 1 1 1 3 3 3 0 Uncharacterized conserved protein ATG16 PF08614.11 KLO05601.1 - 0.59 10.3 19.0 2.3 8.4 7.3 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 KLO05601.1 - 0.65 10.6 14.9 2 9.1 4.9 3.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Nup88 PF10168.9 KLO05601.1 - 0.72 7.6 11.1 1.1 7.0 11.1 1.1 1 0 0 1 1 1 0 Nuclear pore component FapA PF03961.13 KLO05601.1 - 0.84 8.2 7.7 7.2 5.1 8.0 2.2 2 1 1 3 3 3 0 Flagellar Assembly Protein A DUF745 PF05335.13 KLO05601.1 - 0.91 9.2 11.7 0.2 11.3 7.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF16 PF01519.16 KLO05601.1 - 0.94 10.0 6.6 0.36 11.3 3.3 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF948 PF06103.11 KLO05601.1 - 0.99 9.7 5.8 8.3 6.7 1.0 2.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FH2 PF02181.23 KLO05601.1 - 1.2 8.2 8.1 0.44 9.6 1.9 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain DHR10 PF18595.1 KLO05601.1 - 1.2 9.2 18.3 2.1 8.4 2.3 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Occludin_ELL PF07303.13 KLO05601.1 - 1.4 9.7 8.1 0.5 11.1 0.8 2.6 1 1 2 3 3 3 0 Occludin homology domain She9_MDM33 PF05546.11 KLO05601.1 - 1.7 8.4 8.8 5.7 6.7 0.7 2.3 2 0 0 2 2 2 0 She9 / Mdm33 family Exonuc_VII_L PF02601.15 KLO05601.1 - 1.7 8.1 12.0 5 6.6 12.0 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF724 PF05266.14 KLO05601.1 - 1.8 8.3 7.2 0.51 10.1 3.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) EzrA PF06160.12 KLO05601.1 - 1.9 6.5 14.6 12 4.0 14.7 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA IFT57 PF10498.9 KLO05601.1 - 2.2 7.2 12.1 7.4 5.4 11.9 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4472 PF14739.6 KLO05601.1 - 2.4 8.9 10.4 0.86 10.4 3.7 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) XhlA PF10779.9 KLO05601.1 - 2.7 8.3 5.1 7 6.9 0.6 2.6 1 1 1 2 2 2 0 Haemolysin XhlA DUF4349 PF14257.6 KLO05601.1 - 2.8 7.4 15.9 34 3.8 15.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) APG6_N PF17675.1 KLO05601.1 - 2.8 8.5 16.3 0.65 10.5 4.2 2.5 1 1 2 3 3 3 0 Apg6 coiled-coil region Ax_dynein_light PF10211.9 KLO05601.1 - 3.9 7.4 13.4 2.7 7.9 2.5 2.8 1 1 2 3 3 3 0 Axonemal dynein light chain TMF_DNA_bd PF12329.8 KLO05601.1 - 4.8 7.3 13.3 0.73 9.9 0.7 3.4 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 KLO05601.1 - 5 7.6 6.6 15 6.1 0.3 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF641 PF04859.12 KLO05601.1 - 5.4 7.4 11.7 9.5 6.6 1.4 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF2203 PF09969.9 KLO05601.1 - 5.5 7.7 5.9 8.6 7.1 0.8 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.10 KLO05601.1 - 6.5 6.9 11.9 5.7 7.1 7.9 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 KLO05601.1 - 6.5 6.1 14.6 13 5.1 14.6 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMPIT PF07851.13 KLO05601.1 - 6.9 5.8 8.8 1.9 7.7 3.6 1.9 1 1 1 2 2 2 0 TMPIT-like protein PRKG1_interact PF15898.5 KLO05601.1 - 7.1 7.6 15.2 2.2 9.2 8.9 2.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Phage_GP20 PF06810.11 KLO05601.1 - 7.2 6.4 12.7 16 5.3 10.7 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 CENP-Q PF13094.6 KLO05601.1 - 7.5 6.7 17.6 6.4e+02 0.4 16.6 3.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit WD40 PF00400.32 KLO05602.1 - 8.6e-11 42.2 11.2 1.7e-05 25.4 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO05602.1 - 3.2e-08 33.8 1.0 0.043 14.1 0.0 4.4 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO05602.1 - 0.063 12.2 0.1 0.94 8.4 0.1 2.4 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4218 PF13960.6 KLO05603.1 - 0.026 14.1 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) HicA_toxin PF07927.12 KLO05605.1 - 1.8e-05 24.7 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, FUSC PF04632.12 KLO05606.1 - 0.1 11.1 9.2 0.04 12.5 4.5 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Baculo_F PF12259.8 KLO05606.1 - 0.15 10.6 5.5 0.22 10.0 5.5 1.1 1 0 0 1 1 1 0 Baculovirus F protein Lectin_N PF03954.14 KLO05606.1 - 2.8 7.7 6.6 25 4.6 0.0 3.5 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain FAM76 PF16046.5 KLO05606.1 - 4.6 6.5 17.2 0.25 10.6 7.0 2.3 1 1 1 2 2 2 0 FAM76 protein APC_N_CC PF16689.5 KLO05606.1 - 5.4 7.1 6.7 3.3 7.9 0.2 2.7 2 1 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Phage_lysis PF03245.13 KLO05606.1 - 8.7 6.5 14.1 0.23 11.6 3.4 3.1 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein Fez1 PF06818.15 KLO05606.1 - 8.9 6.7 17.9 6.6 7.1 15.1 2.3 2 0 0 2 2 2 0 Fez1 GP52 PF17468.2 KLO05607.1 - 0.1 12.8 0.1 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 Phage gene product 52 Trehalase PF01204.18 KLO05608.1 - 3.4e-170 567.3 0.1 4.2e-170 567.0 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KLO05608.1 - 1.3e-13 50.4 0.2 2.2e-13 49.6 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF676 PF05057.14 KLO05609.1 - 4.5e-41 140.7 0.0 6.4e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KLO05609.1 - 0.052 13.4 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF4254 PF14063.6 KLO05613.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4254) RNA_pol_Rpb2_4 PF04566.13 KLO05613.1 - 0.2 12.0 0.8 19 5.6 0.7 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 FapA PF03961.13 KLO05613.1 - 0.46 9.0 4.7 0.13 10.8 1.6 1.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A LAM_C PF12544.8 KLO05613.1 - 0.7 10.1 0.0 0.7 10.1 0.0 2.2 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Leu_zip PF15294.6 KLO05613.1 - 2.4 7.6 7.9 0.14 11.6 2.5 1.7 2 0 0 2 2 2 0 Leucine zipper Jnk-SapK_ap_N PF09744.9 KLO05613.1 - 5.4 7.2 8.7 0.63 10.2 4.4 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 KLO05613.1 - 7.2 5.9 12.1 2.2 7.5 6.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) WD40 PF00400.32 KLO05616.1 - 1.4e-79 259.9 53.4 9.1e-08 32.7 0.1 15.0 14 0 0 14 14 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO05616.1 - 1.2e-31 108.8 7.6 0.02 15.2 0.0 11.7 2 1 7 10 10 10 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO05616.1 - 8.6e-11 41.4 9.5 0.91 8.4 0.0 9.1 3 2 6 10 10 10 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KLO05616.1 - 3.3e-08 34.1 0.2 7.5e-08 32.9 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KLO05616.1 - 2.1e-06 27.8 0.1 4.6e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 NACHT domain Nbas_N PF15492.6 KLO05616.1 - 5.9e-06 25.8 4.5 3.5 6.9 0.0 6.1 4 2 1 6 6 6 2 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KLO05616.1 - 1.2e-05 23.8 3.3 0.95 7.7 0.1 5.8 6 2 1 7 7 7 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KLO05616.1 - 0.00035 19.3 10.6 0.023 13.4 0.0 5.8 4 2 2 8 8 8 1 Nucleoporin Nup120/160 AAA_22 PF13401.6 KLO05616.1 - 0.004 17.4 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain PD40 PF07676.12 KLO05616.1 - 0.0076 16.2 5.6 85 3.3 0.1 7.6 10 0 0 10 10 9 0 WD40-like Beta Propeller Repeat AAA PF00004.29 KLO05616.1 - 0.014 15.8 0.0 0.19 12.2 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KLO05616.1 - 0.025 15.1 0.0 0.064 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KLO05616.1 - 0.027 14.4 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 KLO05616.1 - 0.029 13.8 0.0 0.077 12.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein APS_kinase PF01583.20 KLO05616.1 - 0.029 14.2 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.14 KLO05616.1 - 0.03 13.6 0.1 0.45 9.7 0.1 2.1 1 1 0 2 2 2 0 KAP family P-loop domain IstB_IS21 PF01695.17 KLO05616.1 - 0.036 13.8 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 KLO05616.1 - 0.043 13.0 0.1 0.095 11.9 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF463 PF04317.12 KLO05616.1 - 0.052 12.5 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_33 PF13671.6 KLO05616.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KLO05616.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RAB3GAP2_N PF14655.6 KLO05616.1 - 0.092 12.0 0.0 1 8.5 0.0 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AAA_25 PF13481.6 KLO05616.1 - 0.15 11.6 0.6 0.6 9.7 0.6 2.0 1 1 0 1 1 1 0 AAA domain RPW8 PF05659.11 KLO05616.1 - 0.18 11.5 4.4 3.2 7.5 0.1 3.5 4 0 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 AAA_30 PF13604.6 KLO05616.1 - 0.18 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Alpha_GJ PF03229.13 KLO05617.1 - 0.024 15.2 2.6 0.032 14.8 0.9 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF4448 PF14610.6 KLO05617.1 - 0.063 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4381 PF14316.6 KLO05617.1 - 0.068 13.4 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) GAPT PF11770.8 KLO05617.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) FixQ PF05545.11 KLO05617.1 - 0.25 11.4 1.4 0.35 10.9 0.3 1.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ adh_short_C2 PF13561.6 KLO05618.1 - 1.1e-52 179.0 5.8 2.7e-50 171.1 5.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO05618.1 - 7.2e-46 156.1 4.0 8.7e-46 155.9 4.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO05618.1 - 1.3e-16 61.0 0.3 1.8e-16 60.6 0.3 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KLO05618.1 - 0.015 15.2 0.5 0.026 14.4 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF881 PF05949.12 KLO05618.1 - 0.034 14.0 0.9 0.075 12.9 0.3 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF881) ADH_zinc_N PF00107.26 KLO05618.1 - 0.11 12.4 3.8 9.5 6.2 0.9 2.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase OPT PF03169.15 KLO05619.1 - 3.8e-194 646.8 59.3 4.4e-194 646.6 59.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 KLO05619.1 - 3.6 7.8 8.8 1.2 9.4 4.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) BCIP PF13862.6 KLO05621.1 - 4.2e-11 43.0 0.1 5.8e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Chorion_3 PF05387.11 KLO05621.1 - 0.084 12.5 0.0 0.084 12.5 0.0 1.0 1 0 0 1 1 1 0 Chorion family 3 GPI-anchored PF10342.9 KLO05623.1 - 5.9e-05 23.8 0.1 0.00016 22.4 0.1 1.6 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KLO05623.1 - 0.12 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 KLO05625.1 - 0.012 16.3 3.3 0.055 14.2 3.3 1.9 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Avl9 PF09794.9 KLO05626.1 - 6e-126 420.2 0.0 8.4e-126 419.7 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KLO05626.1 - 2e-09 37.4 0.1 0.00086 19.2 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 KLO05626.1 - 1.8e-08 34.3 1.4 0.00032 20.4 1.0 2.8 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) DHHC PF01529.20 KLO05627.1 - 1.3e-31 109.5 10.3 1.3e-31 109.5 10.3 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ysc84 PF04366.12 KLO05628.1 - 2.6e-43 146.8 0.1 3.8e-43 146.3 0.1 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator Pkinase_fungal PF17667.1 KLO05629.1 - 4.1e-17 62.1 0.0 8.4e-17 61.0 0.0 1.4 1 1 1 2 2 2 1 Fungal protein kinase OpgC_C PF10129.9 KLO05630.1 - 0.079 11.8 0.0 0.091 11.6 0.0 1.1 1 0 0 1 1 1 0 OpgC protein zf-C2H2 PF00096.26 KLO05632.1 - 8.6e-08 32.2 8.9 0.0057 17.0 0.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO05632.1 - 2.1e-06 28.1 9.6 0.073 13.9 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KLO05632.1 - 0.0014 18.3 0.6 0.36 10.6 0.2 2.6 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-met PF12874.7 KLO05632.1 - 0.0095 16.3 0.5 7.8 7.0 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KLO05632.1 - 0.017 15.5 13.4 1.8 9.1 1.5 4.0 4 0 0 4 4 4 0 Zinc-finger double domain FOXP-CC PF16159.5 KLO05632.1 - 0.15 12.7 1.5 0.64 10.7 0.8 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF2089 PF09862.9 KLO05632.1 - 0.58 10.2 1.6 2.1 8.4 0.0 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2089) zf-C2H2_jaz PF12171.8 KLO05632.1 - 1 9.7 4.4 46 4.5 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Plavaka PF18759.1 KLO05634.1 - 9e-28 97.4 0.0 1.6e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase Apt1 PF10351.9 KLO05635.1 - 0.13 11.1 7.7 0.15 10.9 7.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SWIRM-assoc_2 PF16496.5 KLO05635.1 - 0.46 9.3 6.5 0.56 9.0 6.5 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal FAM76 PF16046.5 KLO05635.1 - 1.8 7.8 9.6 2.7 7.3 9.6 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4614 PF15391.6 KLO05635.1 - 3.6 7.6 13.6 5.7 6.9 13.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Sec10 PF07393.11 KLO05635.1 - 7.2 4.9 6.1 8 4.7 6.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 ORC6 PF05460.13 KLO05635.1 - 8.7 5.5 11.5 12 5.1 11.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NPR3 PF03666.13 KLO05635.1 - 9.2 4.9 11.2 11 4.6 11.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HOOK PF05622.12 KLO05636.1 - 0.22 9.6 0.1 0.32 9.1 0.1 1.1 1 0 0 1 1 1 0 HOOK protein Plavaka PF18759.1 KLO05637.1 - 7.2e-124 413.2 0.0 1e-123 412.7 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase FMO-like PF00743.19 KLO05641.1 - 3e-21 75.4 0.1 8.7e-14 50.8 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KLO05641.1 - 4.5e-20 72.1 0.0 1.6e-16 60.4 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KLO05641.1 - 3.6e-14 52.7 0.1 2.8e-05 23.5 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KLO05641.1 - 7.1e-12 45.1 0.0 3.4e-09 36.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KLO05641.1 - 1.1e-06 29.0 0.2 0.0035 17.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO05641.1 - 3.9e-05 22.5 0.1 0.00023 20.0 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Shikimate_DH PF01488.20 KLO05641.1 - 9.1e-05 22.5 0.1 0.0045 17.0 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KLO05641.1 - 9.2e-05 22.6 0.0 0.00042 20.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KLO05641.1 - 0.00047 19.5 0.4 0.008 15.5 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KLO05641.1 - 0.0019 18.2 0.0 0.049 13.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KLO05641.1 - 0.0023 17.1 0.0 0.0056 15.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 KLO05641.1 - 0.005 17.1 0.0 0.32 11.3 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 KLO05641.1 - 0.016 15.6 0.0 0.58 10.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.24 KLO05641.1 - 0.017 14.7 2.3 0.27 10.7 0.2 3.0 3 1 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 KLO05641.1 - 0.027 13.6 1.0 0.92 8.5 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KLO05641.1 - 0.027 13.8 0.1 0.041 13.2 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KLO05641.1 - 0.042 13.2 0.0 0.84 9.0 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 KLO05641.1 - 0.047 13.0 0.0 2.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KLO05641.1 - 0.068 12.2 0.0 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein DUF4449 PF14613.6 KLO05644.1 - 1.2e-05 25.5 0.0 0.00014 22.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) YtxH PF12732.7 KLO05644.1 - 8.1 7.1 8.7 6.3 7.4 0.3 4.5 6 0 0 6 6 6 0 YtxH-like protein F-box-like PF12937.7 KLO05648.1 - 3.2e-05 23.7 0.0 5.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KLO05648.1 - 0.00081 19.3 0.8 0.0018 18.1 0.8 1.7 1 1 0 1 1 1 1 F-box F-box PF00646.33 KLO05648.1 - 0.0098 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain NicO PF03824.16 KLO05649.1 - 3e-48 164.6 1.4 3e-48 164.6 1.4 2.6 2 1 0 2 2 2 2 High-affinity nickel-transport protein F-box-like PF12937.7 KLO05650.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05650.1 - 0.0013 18.5 0.0 0.0036 17.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain CDC37_N PF03234.14 KLO05651.1 - 5.6e-40 137.2 2.0 2e-39 135.4 0.2 2.4 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KLO05651.1 - 1.8e-33 114.9 0.0 4.4e-33 113.7 0.0 1.7 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KLO05651.1 - 4e-18 65.4 2.8 4.6e-18 65.2 0.0 2.3 2 0 0 2 2 2 1 Cdc37 C terminal domain TAP42 PF04177.12 KLO05651.1 - 0.0073 15.5 0.3 0.012 14.8 0.3 1.3 1 0 0 1 1 1 1 TAP42-like family Rib_recp_KP_reg PF05104.12 KLO05651.1 - 2.9 8.9 11.7 0.8 10.7 8.3 1.7 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Ebp2 PF05890.12 KLO05652.1 - 8.3e-86 287.9 19.7 1.2e-85 287.4 19.7 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Acetyltransf_10 PF13673.7 KLO05654.1 - 8.4e-09 35.4 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO05654.1 - 1e-08 35.5 0.0 2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO05654.1 - 4.2e-06 27.0 0.0 6.2e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_92N PF17678.1 KLO05656.1 - 0.052 13.4 0.0 0.063 13.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 N-terminal domain DUF3328 PF11807.8 KLO05657.1 - 4.2e-12 46.3 0.0 8e-12 45.4 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KLO05658.1 - 1.5e-09 37.9 0.2 2.3e-09 37.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) But2 PF09792.9 KLO05659.1 - 1.5e-05 25.4 0.0 3.2e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain CLTH PF10607.9 KLO05660.1 - 2e-32 112.1 0.2 3.2e-32 111.5 0.2 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Oxidored_FMN PF00724.20 KLO05661.1 - 1.7e-62 211.7 0.0 2.7e-62 211.0 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KLO05661.1 - 0.019 14.1 0.1 0.32 10.1 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) PcrB PF01884.17 KLO05661.1 - 0.038 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 PcrB family DUF1611_N PF17396.2 KLO05661.1 - 0.057 13.7 0.1 0.36 11.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain Oxidored_FMN PF00724.20 KLO05662.1 - 6.1e-66 223.0 0.0 7.1e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1611_N PF17396.2 KLO05662.1 - 0.0086 16.3 0.1 2.7 8.3 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1611_N) Rossmann-like domain PcrB PF01884.17 KLO05662.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 PcrB family FMN_dh PF01070.18 KLO05662.1 - 0.29 10.1 1.0 13 4.6 0.2 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Mem_trans PF03547.18 KLO05663.1 - 4.8e-39 133.8 0.0 5.8e-34 117.1 0.0 2.4 2 1 0 2 2 2 2 Membrane transport protein PCMT PF01135.19 KLO05664.1 - 2.5e-72 243.0 0.0 3e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KLO05664.1 - 1.3e-09 38.0 0.0 2.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO05664.1 - 1.1e-06 29.3 0.0 2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO05664.1 - 5.4e-05 23.1 0.0 8.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KLO05664.1 - 0.00035 20.3 0.0 0.00051 19.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 KLO05664.1 - 0.0022 17.4 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KLO05664.1 - 0.0032 18.1 0.0 0.0056 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO05664.1 - 0.0046 16.5 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Fibrillarin PF01269.17 KLO05664.1 - 0.0058 15.8 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin N6_N4_Mtase PF01555.18 KLO05664.1 - 0.015 15.0 0.0 0.092 12.4 0.0 2.0 2 0 0 2 2 2 0 DNA methylase PrmA PF06325.13 KLO05664.1 - 0.021 14.3 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KLO05664.1 - 0.031 13.9 0.0 0.063 12.9 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KLO05664.1 - 0.08 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Nucleo_P87 PF07267.11 KLO05666.1 - 0.31 9.9 6.1 0.45 9.3 6.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC27 PF09507.10 KLO05666.1 - 1.8 7.9 15.2 0.66 9.3 11.9 1.8 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 KLO05666.1 - 2.3 6.3 8.6 3 6.0 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 KLO05666.1 - 6.2 7.3 8.4 16 6.0 8.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Transposase_21 PF02992.14 KLO05667.1 - 4.7e-08 32.5 0.0 6.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 KLO05667.1 - 0.00091 18.5 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF4218 PF13960.6 KLO05667.1 - 0.0047 16.5 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) QH-AmDH_gamma PF08992.11 KLO05667.1 - 0.063 13.3 0.4 0.15 12.1 0.4 1.6 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit IHABP4_N PF16174.5 KLO05669.1 - 0.0025 18.4 4.2 0.0025 18.4 4.2 2.2 2 0 0 2 2 2 1 Intracellular hyaluronan-binding protein 4 N-terminal SLC12 PF03522.15 KLO05669.1 - 6.8 5.6 7.3 10 5.1 7.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 WD40 PF00400.32 KLO05670.1 - 0.004 18.0 1.0 16 6.6 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Lactonase PF10282.9 KLO05670.1 - 0.14 11.3 0.0 14 4.8 0.0 2.6 1 1 2 3 3 3 0 Lactonase, 7-bladed beta-propeller Bac_rhamnosid_C PF17390.2 KLO05670.1 - 0.17 11.7 0.1 4.3 7.2 0.0 2.5 1 1 1 2 2 2 0 Bacterial alpha-L-rhamnosidase C-terminal domain STE3 PF02076.15 KLO05673.1 - 4e-57 193.6 14.9 4.7e-57 193.4 14.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor UPF0182 PF03699.13 KLO05673.1 - 0.64 8.1 2.8 0.89 7.6 2.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) AA_permease_2 PF13520.6 KLO05674.1 - 6.4e-68 229.5 36.4 8.4e-68 229.1 36.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KLO05674.1 - 6.8e-17 61.2 24.8 1e-16 60.6 24.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KLO05675.1 - 7e-71 239.3 32.9 9e-71 238.9 32.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KLO05675.1 - 8.6e-17 60.9 23.3 1.2e-16 60.3 23.3 1.1 1 0 0 1 1 1 1 Amino acid permease SMN PF06003.12 KLO05679.1 - 6.4 5.9 12.2 0.96 8.7 7.8 1.9 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) DUF3592 PF12158.8 KLO05680.1 - 0.14 12.2 0.1 0.24 11.4 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) Pro_isomerase PF00160.21 KLO05682.1 - 2.3e-44 151.4 0.2 2.6e-44 151.3 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 KLO05683.1 - 2.8e-44 151.2 0.2 3.1e-44 151.0 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GRASP55_65 PF04495.14 KLO05684.1 - 3.1e-59 199.2 0.0 1.1e-42 145.6 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KLO05684.1 - 0.00058 19.7 0.1 0.014 15.2 0.0 2.7 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 KLO05684.1 - 0.00065 20.0 0.0 1.3 9.4 0.0 2.3 2 0 0 2 2 2 2 PDZ domain DSPc PF00782.20 KLO05685.1 - 7.5e-26 90.5 0.0 1.1e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KLO05685.1 - 0.0002 21.0 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KLO05685.1 - 0.012 16.0 0.0 0.1 12.9 0.0 2.1 2 0 0 2 2 2 0 Rit1 DUSP-like domain CDKN3 PF05706.12 KLO05685.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) MATH PF00917.26 KLO05686.1 - 2.3e-06 27.7 0.1 4.5e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 MATH domain BTB PF00651.31 KLO05686.1 - 4.8e-05 23.5 0.1 1.4 9.2 0.0 3.3 3 0 0 3 3 3 2 BTB/POZ domain UPF0160 PF03690.13 KLO05687.1 - 3e-136 454.2 0.0 3.4e-136 454.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF4722 PF15849.5 KLO05688.1 - 3 7.5 6.5 0.93 9.2 2.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4722) CoA_transf_3 PF02515.17 KLO05689.1 - 2.7e-48 165.0 0.0 1.8e-42 145.8 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III Ribosomal_L17 PF01196.19 KLO05689.1 - 0.026 15.4 0.0 0.056 14.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L17 MFS_1 PF07690.16 KLO05690.1 - 6.5e-25 87.8 31.2 9.7e-25 87.2 31.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KLO05691.1 - 1.1e-31 110.0 29.5 1.7e-31 109.4 29.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3671 PF12420.8 KLO05691.1 - 0.75 9.9 5.0 1.7 8.8 0.1 3.3 2 2 1 3 3 3 0 Protein of unknown function DUF3533 PF12051.8 KLO05693.1 - 1.1e-64 218.7 17.5 1.4e-64 218.4 17.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF3817 PF12823.7 KLO05693.1 - 0.076 13.8 3.7 0.26 12.1 3.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3817) FMN_bind_2 PF04299.12 KLO05694.1 - 4.9e-34 117.5 0.0 6.3e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain NCE101 PF11654.8 KLO05695.1 - 2.8e-16 59.0 0.0 3.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 RdRP PF05183.12 KLO05696.1 - 3.8e-84 283.4 0.0 5.5e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase ATP_bind_1 PF03029.17 KLO05697.1 - 1.4e-72 244.4 0.5 4.8e-72 242.6 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KLO05697.1 - 0.00035 20.2 0.0 0.048 13.2 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KLO05697.1 - 0.00088 19.0 0.1 0.0027 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KLO05697.1 - 0.00089 19.2 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 KLO05697.1 - 0.0011 19.1 0.0 0.0027 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 KLO05697.1 - 0.0015 18.2 0.2 0.015 14.9 0.2 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KLO05697.1 - 0.0028 17.3 0.0 0.15 11.7 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 KLO05697.1 - 0.003 17.6 0.0 0.0079 16.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 KLO05697.1 - 0.0082 16.1 0.1 0.061 13.2 0.1 2.2 1 1 0 1 1 1 1 NTPase NB-ARC PF00931.22 KLO05697.1 - 0.0087 15.3 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain MeaB PF03308.16 KLO05697.1 - 0.0098 14.9 0.0 0.86 8.5 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 KLO05697.1 - 0.011 15.5 0.0 0.4 10.4 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KLO05697.1 - 0.013 15.4 0.0 11 5.9 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase FeoB_N PF02421.18 KLO05697.1 - 0.017 14.6 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_30 PF13604.6 KLO05697.1 - 0.028 14.1 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KLO05697.1 - 0.029 14.8 0.0 0.14 12.5 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KLO05697.1 - 0.037 13.4 0.2 1.9 7.8 0.0 2.9 3 1 0 3 3 3 0 FtsK/SpoIIIE family G-alpha PF00503.20 KLO05697.1 - 0.059 12.5 4.1 0.59 9.2 0.1 2.9 2 1 0 3 3 3 0 G-protein alpha subunit AAA_19 PF13245.6 KLO05697.1 - 0.069 13.5 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KLO05697.1 - 0.07 13.4 0.0 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KLO05697.1 - 0.11 13.1 0.3 0.61 10.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF92 PF01940.16 KLO05698.1 - 2.6e-75 252.9 9.8 3.1e-75 252.6 9.8 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 NAD_binding_9 PF13454.6 KLO05699.1 - 0.0057 16.7 0.0 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding DUF1752 PF08550.10 KLO05700.1 - 0.068 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) DUF3295 PF11702.8 KLO05701.1 - 5.3e-09 36.0 22.1 5.3e-09 36.0 22.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3295) Ribosomal_S25 PF03297.15 KLO05701.1 - 1.7 8.9 4.7 0.26 11.5 0.6 1.7 2 0 0 2 2 2 0 S25 ribosomal protein Fungal_trans PF04082.18 KLO05702.1 - 3.5e-27 95.1 0.1 6.1e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO05702.1 - 2.3e-05 24.4 5.5 4.4e-05 23.5 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.20 KLO05703.1 - 2.5e-25 89.4 0.0 4.3e-24 85.4 0.0 2.5 1 1 0 1 1 1 1 Aldose 1-epimerase FANCF PF11107.8 KLO05705.1 - 0.093 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) ADH_zinc_N PF00107.26 KLO05706.1 - 1.2e-19 70.5 0.0 2.1e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO05706.1 - 2.2e-09 38.5 0.0 5.6e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO05706.1 - 3.6e-09 36.5 0.0 6.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KLO05706.1 - 1.1e-05 25.1 0.1 1.7e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_2 PF16884.5 KLO05706.1 - 0.00035 20.4 0.0 0.0016 18.3 0.0 2.0 2 1 0 2 2 2 1 N-terminal domain of oxidoreductase SapC PF07277.11 KLO05706.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 SapC Fapy_DNA_glyco PF01149.24 KLO05707.1 - 8.8e-31 106.9 0.0 2.3e-30 105.6 0.0 1.7 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KLO05707.1 - 2e-20 72.6 0.0 5.9e-20 71.1 0.0 1.8 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KLO05707.1 - 0.00074 18.4 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 KLO05707.1 - 0.0049 17.2 0.1 0.046 14.1 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S13/S18 Csm1 PF12539.8 KLO05707.1 - 0.11 13.2 0.0 0.31 11.7 0.0 1.8 2 0 0 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 Utp12 PF04003.12 KLO05708.1 - 1.2e-25 89.9 0.1 2e-25 89.2 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KLO05708.1 - 4.8e-06 26.8 0.4 0.07 13.4 0.1 4.3 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KLO05708.1 - 7.7e-05 23.4 5.2 0.018 15.9 0.3 4.5 4 1 0 4 4 4 1 WD domain, G-beta repeat Pkinase PF00069.25 KLO05709.1 - 4e-72 242.8 0.0 6.2e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05709.1 - 1.4e-33 116.3 0.4 3.1e-33 115.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KLO05709.1 - 0.002 17.2 0.1 0.045 12.7 0.1 2.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KLO05709.1 - 0.011 15.1 0.0 0.011 15.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KLO05709.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Med15 PF09606.10 KLO05709.1 - 0.48 9.1 30.3 0.66 8.6 30.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 KLO05709.1 - 0.53 10.2 16.2 0.7 9.8 16.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit tRNA_anti-like PF12869.7 KLO05709.1 - 1.5 8.4 4.8 2.5 7.7 4.8 1.2 1 0 0 1 1 1 0 tRNA_anti-like MFS_1 PF07690.16 KLO05710.1 - 4.7e-33 114.6 15.3 5.5e-33 114.3 14.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KLO05710.1 - 2.7e-05 23.2 11.8 0.0004 19.3 5.0 2.2 1 1 0 2 2 2 2 MFS_1 like family MFS_4 PF06779.14 KLO05710.1 - 0.00099 18.5 11.0 0.019 14.3 4.4 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KLO05710.1 - 0.0034 15.7 4.6 0.024 12.9 0.3 2.6 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MccV PF17508.2 KLO05710.1 - 0.18 12.4 0.8 0.76 10.4 0.1 2.3 2 0 0 2 2 2 0 Microcin V bacteriocin RhodobacterPufX PF11511.8 KLO05710.1 - 1.6 8.4 4.2 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 Intrinsic membrane protein PufX MFS_1 PF07690.16 KLO05711.1 - 1.4e-43 149.2 36.9 1.4e-30 106.4 7.7 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KLO05711.1 - 1.2e-13 50.5 26.1 6.3e-08 31.6 6.4 3.8 2 2 2 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.7 KLO05711.1 - 1.2e-07 31.0 16.5 5.8e-05 22.1 0.8 3.6 2 2 0 3 3 3 3 MFS_1 like family MFS_4 PF06779.14 KLO05711.1 - 5.8e-05 22.6 10.5 0.084 12.1 0.1 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KLO05711.1 - 0.0016 16.8 0.9 0.0016 16.8 0.9 1.9 3 1 1 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family RhodobacterPufX PF11511.8 KLO05711.1 - 0.13 11.9 2.6 28 4.4 0.0 4.2 5 0 0 5 5 5 0 Intrinsic membrane protein PufX CCB1 PF12046.8 KLO05711.1 - 0.4 10.0 1.8 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B DGF-1_C PF11040.8 KLO05712.1 - 0.18 11.9 0.4 0.22 11.6 0.4 1.2 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus zf-MYND PF01753.18 KLO05720.1 - 1.9e-09 37.4 19.2 3.9e-09 36.4 19.2 1.5 1 0 0 1 1 1 1 MYND finger DUF4936 PF16290.5 KLO05720.1 - 0.06 14.0 0.1 0.17 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4936) FTCD_N PF07837.12 KLO05720.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain Fic PF02661.18 KLO05720.1 - 0.18 12.7 0.5 0.65 10.9 0.3 2.1 2 0 0 2 2 2 0 Fic/DOC family FA_desaturase PF00487.24 KLO05721.1 - 1.9e-24 86.9 11.5 3.3e-24 86.1 11.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KLO05721.1 - 5.6e-18 64.2 0.4 9.4e-18 63.4 0.4 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Bin3 PF06859.12 KLO05722.1 - 1.3e-38 131.9 0.0 1.9e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 KLO05722.1 - 2.9e-11 43.5 0.0 3.7e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO05722.1 - 2.1e-10 40.6 0.0 0.00017 21.4 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KLO05722.1 - 2.6e-08 34.5 0.0 0.00017 22.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KLO05722.1 - 1.1e-06 29.3 0.0 4.1e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO05722.1 - 1.5e-05 25.6 0.0 0.038 14.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KLO05722.1 - 0.0034 16.9 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KLO05722.1 - 0.0046 16.4 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KLO05722.1 - 0.0085 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KLO05722.1 - 0.1 12.1 0.0 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.20 KLO05722.1 - 0.12 11.7 0.0 9.1 5.5 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase UCH PF00443.29 KLO05723.1 - 1.4e-39 136.2 0.0 4.1e-39 134.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KLO05723.1 - 3.4e-10 40.0 0.5 5.2e-05 23.0 0.0 3.5 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Aminotran_1_2 PF00155.21 KLO05724.1 - 9.5e-60 202.7 0.0 1.1e-59 202.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KLO05724.1 - 0.0065 15.1 0.0 0.014 13.9 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KLO05724.1 - 0.0067 15.4 0.0 0.022 13.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Atg14 PF10186.9 KLO05725.1 - 2.2e-37 128.9 0.0 6.2e-37 127.4 0.0 1.7 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 YscO PF07321.12 KLO05725.1 - 0.0047 16.9 6.1 0.14 12.2 1.1 2.3 2 0 0 2 2 2 2 Type III secretion protein YscO SPX PF03105.19 KLO05725.1 - 7.1 6.4 10.3 19 5.1 10.3 1.8 1 1 0 1 1 1 0 SPX domain DUF4436 PF14494.6 KLO05726.1 - 0.00012 21.5 7.4 0.00019 20.9 7.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF1471 PF07338.13 KLO05727.1 - 0.17 11.9 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) zf-MYND PF01753.18 KLO05730.1 - 3.1e-08 33.6 18.2 7.6e-08 32.3 18.2 1.7 1 0 0 1 1 1 1 MYND finger TPR_14 PF13428.6 KLO05730.1 - 0.041 14.7 0.7 8.1 7.6 0.0 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat IFRD PF05004.13 KLO05730.1 - 0.062 12.4 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) zf-MYND PF01753.18 KLO05731.1 - 2.8e-10 40.1 18.4 3.9e-10 39.7 18.4 1.2 1 0 0 1 1 1 1 MYND finger Peptidase_C33 PF05412.12 KLO05731.1 - 0.007 16.4 0.3 0.007 16.4 0.3 1.0 1 0 0 1 1 1 1 Equine arterivirus Nsp2-type cysteine proteinase PolC_DP2 PF03833.13 KLO05731.1 - 2.8 5.7 5.9 2.9 5.7 5.9 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF1707 PF08044.11 KLO05734.1 - 0.13 12.3 0.6 0.27 11.3 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) DDE_Tnp_4 PF13359.6 KLO05735.1 - 6.7e-29 100.6 0.0 9.5e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KLO05735.1 - 0.0097 15.6 1.4 0.058 13.0 1.4 2.0 1 1 0 1 1 1 1 Transposase DDE domain CDO_I PF05995.12 KLO05735.1 - 0.037 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Cysteine dioxygenase type I TetR_N PF00440.23 KLO05735.1 - 0.095 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Sigma70_r4 PF04545.16 KLO05735.1 - 0.11 12.1 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 K_trans PF02705.16 KLO05737.1 - 5.1e-175 583.0 5.3 1.3e-174 581.6 5.3 1.6 1 1 0 1 1 1 1 K+ potassium transporter F-box-like PF12937.7 KLO05738.1 - 1.4e-10 40.9 0.8 1.4e-10 40.9 0.8 2.3 3 0 0 3 3 3 1 F-box-like Allantoicase PF03561.15 KLO05740.1 - 2.9e-93 309.4 0.0 1.2e-46 158.2 0.0 2.4 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 KLO05740.1 - 3.1e-49 167.3 0.0 4.6e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase SWI-SNF_Ssr4 PF08549.10 KLO05741.1 - 3.2e-26 92.2 0.0 1.4e-15 57.1 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1750) Rhomboid_SP PF12595.8 KLO05741.1 - 0.081 12.3 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Rhomboid serine protease BRE1 PF08647.11 KLO05742.1 - 5.6e-11 42.4 9.2 5.6e-11 42.4 9.2 7.2 6 2 2 8 8 5 2 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KLO05742.1 - 6.2e-07 29.2 9.7 1.6e-06 27.9 9.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO05742.1 - 2.6e-06 27.2 12.0 2.6e-06 27.2 12.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO05742.1 - 1.7e-05 24.5 10.7 1.7e-05 24.5 10.7 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO05742.1 - 1.9e-05 24.5 12.8 1.9e-05 24.5 12.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Spc7 PF08317.11 KLO05742.1 - 4.2e-05 22.6 73.2 0.027 13.3 11.3 4.8 2 1 1 4 4 4 4 Spc7 kinetochore protein zf-RING_2 PF13639.6 KLO05742.1 - 5.5e-05 23.4 11.2 5.5e-05 23.4 11.2 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KLO05742.1 - 0.00019 21.3 7.5 0.00019 21.3 7.5 2.1 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KLO05742.1 - 0.00058 19.7 8.0 0.0012 18.6 8.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ATG16 PF08614.11 KLO05742.1 - 0.013 15.8 23.6 0.013 15.8 23.6 6.5 1 1 5 6 6 5 0 Autophagy protein 16 (ATG16) BOFC_N PF08977.10 KLO05742.1 - 0.017 15.1 0.3 0.048 13.6 0.3 1.8 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal zf-RING_6 PF14835.6 KLO05742.1 - 0.072 13.0 3.0 0.16 11.9 3.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 KLO05742.1 - 0.37 10.9 5.6 1.4 9.1 5.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_5 PF17121.5 KLO05742.1 - 0.4 10.6 5.9 0.94 9.4 5.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KLO05742.1 - 0.66 10.3 11.0 0.12 12.7 6.6 2.1 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 KLO05742.1 - 0.78 9.6 5.3 1.6 8.6 5.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KLO05742.1 - 0.94 9.7 10.8 0.23 11.7 7.3 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Ribosomal_S9 PF00380.19 KLO05743.1 - 8.1e-44 149.0 0.0 1.2e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 CASP_C PF08172.12 KLO05744.1 - 7.1e-74 248.3 2.5 7.1e-74 248.3 2.5 3.8 2 1 2 4 4 4 1 CASP C terminal Golgin_A5 PF09787.9 KLO05744.1 - 0.0016 18.0 2.7 0.0016 18.0 2.7 4.4 3 1 1 4 4 4 3 Golgin subfamily A member 5 KLRAQ PF10205.9 KLO05744.1 - 0.011 15.9 1.3 0.011 15.9 1.3 5.3 3 2 1 5 5 5 0 Predicted coiled-coil domain-containing protein NYD-SP28_assoc PF14775.6 KLO05744.1 - 0.059 13.5 6.2 4.6 7.4 0.6 4.1 3 0 0 3 3 3 0 Sperm tail C-terminal domain betaPIX_CC PF16523.5 KLO05744.1 - 0.061 13.2 0.2 0.061 13.2 0.2 4.3 4 1 1 5 5 5 0 betaPIX coiled coil WD40_alt PF14077.6 KLO05744.1 - 0.61 10.0 10.5 7.9 6.4 0.3 4.4 4 0 0 4 4 4 0 Alternative WD40 repeat motif BSD PF03909.17 KLO05745.1 - 1.8e-17 63.0 0.1 5.1e-13 48.8 0.0 2.5 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 KLO05745.1 - 1.5e-15 57.3 0.0 3.6e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain HBS1_N PF08938.10 KLO05745.1 - 0.1 12.9 0.2 27 5.2 0.0 2.7 2 0 0 2 2 2 0 HBS1 N-terminus Put_Phosphatase PF06888.12 KLO05746.1 - 2.6e-55 187.4 0.0 2.9e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 KLO05746.1 - 8.6e-08 32.8 0.0 2e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KLO05746.1 - 0.0023 18.2 0.0 0.015 15.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 KLO05746.1 - 0.0055 16.2 0.1 0.088 12.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2608) HAD_2 PF13419.6 KLO05746.1 - 0.051 13.7 0.4 20 5.2 0.0 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KLO05747.1 - 4.2e-49 167.3 0.0 8.5e-49 166.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05747.1 - 5.2e-21 75.1 0.0 8.3e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO05747.1 - 0.00013 22.0 1.8 0.00017 21.6 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO05747.1 - 0.003 17.2 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KLO05747.1 - 0.072 12.7 0.3 0.17 11.5 0.3 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase TMEM132D_N PF15705.5 KLO05747.1 - 0.31 10.9 3.5 0.67 9.8 3.5 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term PAC4 PF16093.5 KLO05748.1 - 1.3e-22 79.8 0.1 1.6e-22 79.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 DUF5566 PF17721.1 KLO05748.1 - 0.088 13.1 0.1 0.093 13.0 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5566) DUF4527 PF15030.6 KLO05749.1 - 0.00043 19.8 2.5 0.00043 19.8 2.5 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF4527) Ead_Ea22 PF13935.6 KLO05749.1 - 0.00075 20.2 0.4 0.00097 19.8 0.4 1.2 1 0 0 1 1 1 1 Ead/Ea22-like protein TACC_C PF05010.14 KLO05749.1 - 0.011 15.6 3.1 0.16 11.7 2.1 2.2 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal T2SSM_b PF10741.9 KLO05749.1 - 0.03 14.1 0.4 0.067 13.0 0.4 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b Spc7 PF08317.11 KLO05749.1 - 0.032 13.1 2.9 0.042 12.7 2.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 KLO05749.1 - 0.034 13.9 2.4 0.034 13.9 2.4 2.3 1 1 2 3 3 3 0 Septum formation initiator XLF PF09302.11 KLO05749.1 - 0.036 14.2 2.8 0.074 13.2 2.8 1.7 1 1 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component SapC PF07277.11 KLO05749.1 - 0.049 13.2 0.3 0.053 13.1 0.3 1.1 1 0 0 1 1 1 0 SapC Armet PF10208.9 KLO05749.1 - 0.059 13.3 0.2 0.086 12.8 0.2 1.3 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding FlaC_arch PF05377.11 KLO05749.1 - 0.13 12.6 1.9 0.57 10.6 1.9 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Alpha-amylase PF00128.24 KLO05750.1 - 3.9e-88 296.3 0.0 6.1e-88 295.6 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KLO05750.1 - 0.00024 21.2 0.0 0.0008 19.5 0.0 2.0 1 1 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Glyco_hydro_3 PF00933.21 KLO05752.1 - 1.3e-66 225.2 0.0 1.7e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain F-box-like PF12937.7 KLO05753.1 - 3.8e-06 26.7 0.0 1.5e-05 24.8 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05753.1 - 9 6.3 8.5 0.7 9.8 0.5 3.2 4 0 0 4 4 4 0 F-box domain Lactamase_B_2 PF12706.7 KLO05756.1 - 9.9e-25 87.2 0.0 4.6e-23 81.8 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KLO05756.1 - 2.2e-06 27.8 0.2 4.2e-06 26.9 0.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KLO05756.1 - 0.034 13.6 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain PIN PF01850.21 KLO05756.1 - 0.077 13.5 0.0 0.25 11.8 0.0 1.8 2 0 0 2 2 2 0 PIN domain DUF1541 PF07563.11 KLO05756.1 - 0.13 12.1 0.4 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1541) Lactamase_B_3 PF13483.6 KLO05756.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Polysacc_lyase PF14099.6 KLO05757.1 - 0.0045 16.9 0.2 0.2 11.5 0.1 2.8 2 1 0 3 3 3 1 Polysaccharide lyase Amidohydro_3 PF07969.11 KLO05758.1 - 1.2e-15 58.0 7.4 1.7e-07 31.1 0.0 4.2 4 0 0 4 4 4 4 Amidohydrolase family Amidohydro_1 PF01979.20 KLO05758.1 - 4.4e-15 55.9 0.1 2.3e-10 40.3 0.0 3.2 3 0 0 3 3 3 3 Amidohydrolase family Lipase_3 PF01764.25 KLO05759.1 - 8.4e-14 51.6 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KLO05759.1 - 0.015 14.8 0.0 0.044 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 KLO05760.1 - 1.8e-20 73.2 0.0 2.5e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KLO05760.1 - 0.00016 22.4 0.3 0.00037 21.2 0.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Rad21_Rec8 PF04824.16 KLO05760.1 - 0.11 11.8 0.5 0.18 11.1 0.5 1.3 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein F-box-like PF12937.7 KLO05761.1 - 2.2e-08 33.9 0.1 5e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05761.1 - 0.025 14.5 1.2 0.044 13.7 0.1 2.0 2 0 0 2 2 2 0 F-box domain Ribosomal_S7e PF01251.18 KLO05761.1 - 0.24 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S7e Nipped-B_C PF12830.7 KLO05762.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Asp_protease_2 PF13650.6 KLO05765.1 - 2.5e-06 28.1 0.1 3.9e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KLO05765.1 - 1.8e-05 24.5 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KLO05765.1 - 4.9e-05 23.8 0.0 9.5e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBX PF00789.20 KLO05768.1 - 9.2e-13 48.2 0.3 1.9e-12 47.2 0.3 1.5 1 0 0 1 1 1 1 UBX domain PITH PF06201.13 KLO05769.1 - 8.4e-34 117.0 0.0 1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain Glyco_hydro_79C PF16862.5 KLO05770.1 - 7.6e-17 62.1 0.1 1.7e-16 60.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Citrate_synt PF00285.21 KLO05771.1 - 1e-99 334.1 0.0 1.3e-99 333.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Methyltransf_4 PF02390.17 KLO05772.1 - 2.5e-57 193.1 0.0 4.3e-57 192.3 0.0 1.3 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KLO05772.1 - 0.0006 20.5 0.0 0.017 15.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KLO05772.1 - 0.0034 16.9 0.0 0.41 10.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KLO05772.1 - 0.018 15.8 0.0 0.053 14.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KLO05772.1 - 0.031 14.9 0.0 11 6.8 0.0 3.2 3 0 0 3 3 3 0 Methyltransferase domain Alba PF01918.21 KLO05773.1 - 0.00026 20.8 0.0 0.92 9.4 0.0 2.6 2 0 0 2 2 2 2 Alba DUF997 PF06196.12 KLO05775.1 - 0.043 13.8 0.5 0.062 13.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) ANAPC10 PF03256.16 KLO05776.1 - 3.2e-50 170.4 0.0 3.9e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KLO05776.1 - 0.022 14.9 0.0 0.066 13.3 0.0 1.7 1 1 0 1 1 1 0 F5/8 type C domain PHD PF00628.29 KLO05777.1 - 4e-08 33.0 6.9 7.8e-08 32.1 6.9 1.5 1 0 0 1 1 1 1 PHD-finger WSD PF15613.6 KLO05777.1 - 0.065 13.7 0.0 0.065 13.7 0.0 4.0 4 1 0 4 4 4 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KLO05777.1 - 0.089 13.1 0.4 0.16 12.3 0.4 1.4 1 0 0 1 1 1 0 DDT domain zf-HC5HC2H PF13771.6 KLO05777.1 - 0.21 11.9 1.5 0.49 10.7 1.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Aminotran_5 PF00266.19 KLO05778.1 - 2.1e-18 66.4 0.0 3.7e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KLO05778.1 - 6.6e-08 32.1 0.0 9.8e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KLO05778.1 - 0.00024 20.5 0.0 0.034 13.5 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Cu-oxidase_2 PF07731.14 KLO05778.1 - 0.0098 15.6 0.0 0.0098 15.6 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase Ribul_P_3_epim PF00834.19 KLO05778.1 - 0.16 11.4 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family F-box-like PF12937.7 KLO05779.1 - 0.00018 21.3 0.8 0.0004 20.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like Spin-Ssty PF02513.17 KLO05779.1 - 0.25 11.1 0.5 0.75 9.6 0.5 1.8 1 0 0 1 1 1 0 Spin/Ssty Family F-box-like PF12937.7 KLO05780.1 - 2.2e-05 24.3 0.1 8.2e-05 22.4 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO05781.1 - 0.013 15.4 3.3 0.038 13.9 3.3 1.9 1 1 0 1 1 1 0 F-box-like F-box-like PF12937.7 KLO05782.1 - 0.00043 20.1 1.6 0.0015 18.3 1.6 2.1 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO05783.1 - 0.0043 16.9 4.7 0.0043 16.9 4.7 2.4 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO05784.1 - 0.00062 19.6 0.6 0.0032 17.3 0.1 2.5 2 0 0 2 2 2 1 F-box-like Aldo_ket_red PF00248.21 KLO05785.1 - 1.3e-71 241.3 0.3 1.4e-71 241.1 0.3 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LOH1CR12 PF10158.9 KLO05785.1 - 0.003 17.6 0.3 0.096 12.7 0.0 2.2 2 0 0 2 2 2 1 Tumour suppressor protein DUF2890 PF11081.8 KLO05786.1 - 0.47 10.5 4.4 0.97 9.5 4.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) ORC6 PF05460.13 KLO05788.1 - 3.7 6.7 10.1 3.9 6.6 10.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Sorb PF02208.16 KLO05789.1 - 2.2 8.2 6.0 1.8 8.4 0.3 2.8 3 0 0 3 3 3 0 Sorbin homologous domain KOW PF00467.29 KLO05791.1 - 1.6e-11 43.8 11.8 0.0085 16.0 0.1 6.3 6 0 0 6 6 6 5 KOW motif DUF3912 PF13051.6 KLO05791.1 - 1.2e-06 28.6 0.3 0.0019 18.4 0.0 4.4 5 0 0 5 5 5 1 Protein of unknown function (DUF3912) Spt5-NGN PF03439.13 KLO05791.1 - 0.045 13.6 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section KDZ PF18758.1 KLO05793.1 - 2.8e-50 171.0 2.4 5.7e-50 170.0 2.4 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO05793.1 - 1.1e-23 83.5 0.1 2.3e-23 82.4 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KLO05793.1 - 0.16 11.8 2.3 0.57 10.0 0.0 2.6 2 1 1 3 3 3 0 CxC3 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KLO05793.1 - 0.2 11.8 3.3 0.52 10.5 3.3 1.7 1 0 0 1 1 1 0 B-box zinc finger Dak2 PF02734.17 KLO05794.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 DAK2 domain Helicase_C PF00271.31 KLO05798.1 - 2.6e-11 43.8 0.0 1.3e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO05798.1 - 4.1e-08 33.2 0.0 8.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Abhydrolase_4 PF08386.10 KLO05805.1 - 5.1e-24 84.4 0.1 9.2e-24 83.5 0.1 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KLO05805.1 - 1.6e-22 80.4 0.1 2.8e-18 66.5 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KLO05806.1 - 1.5e-25 89.3 0.0 2.8e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KLO05806.1 - 2.7e-16 60.0 0.1 4.6e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KLO05807.1 - 9.2e-14 51.4 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein Pkinase PF00069.25 KLO05808.1 - 1.2e-33 116.7 0.0 1.3e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05808.1 - 1e-30 106.9 0.0 1.6e-30 106.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO05808.1 - 0.0028 17.0 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 KLO05813.1 - 5.6e-09 35.7 0.0 8.8e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO05813.1 - 5.9e-08 32.4 0.0 7.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DNA_binding_1 PF01035.20 KLO05814.1 - 3.9e-28 97.4 0.0 5.3e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HMG_box PF00505.19 KLO05815.1 - 3.5e-14 52.9 0.1 4.6e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO05815.1 - 4.5e-07 30.4 0.0 5.3e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 HMG-box domain Ndc1_Nup PF09531.10 KLO05816.1 - 4.7 5.8 4.6 5.6 5.5 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase_Tyr PF07714.17 KLO05817.1 - 1.2e-36 126.4 0.0 1.9e-36 125.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO05817.1 - 2e-32 112.6 0.0 2.5e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain zf-B_box PF00643.24 KLO05817.1 - 4.7 7.5 9.1 2.2 8.5 1.5 3.1 3 0 0 3 3 3 0 B-box zinc finger zf-RanBP PF00641.18 KLO05817.1 - 6.8 6.1 8.9 7.5 6.0 0.1 3.0 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Filamin PF00630.19 KLO05818.1 - 0.12 13.2 0.0 0.15 12.9 0.0 1.3 1 0 0 1 1 1 0 Filamin/ABP280 repeat His_Phos_1 PF00300.22 KLO05821.1 - 0.058 13.1 0.8 1.1 8.9 0.0 2.1 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 1) SAM_2 PF07647.17 KLO05822.1 - 0.086 13.0 0.0 0.22 11.7 0.0 1.7 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) NPV_P10 PF05531.12 KLO05823.1 - 0.17 12.4 0.1 0.35 11.4 0.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein F-box-like PF12937.7 KLO05824.1 - 6.1e-07 29.2 0.1 1.6e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO05825.1 - 6.2e-06 26.0 0.0 2e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO05825.1 - 1.9 9.0 7.8 8.8 6.9 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO05826.1 - 1.2e-08 34.7 0.1 3e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO05827.1 - 4.9e-07 29.5 0.0 1.8e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 F-box-like Img2 PF05046.14 KLO05827.1 - 0.15 12.4 0.0 0.43 10.9 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) G-alpha PF00503.20 KLO05829.1 - 3.1e-115 385.1 0.1 3.6e-115 384.9 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO05829.1 - 6.4e-14 51.8 0.2 1.7e-08 34.1 0.1 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KLO05829.1 - 0.00042 19.8 0.0 0.52 9.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KLO05829.1 - 0.0057 16.9 0.1 0.62 10.3 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase WAK PF08488.11 KLO05829.1 - 0.016 15.7 0.1 0.089 13.3 0.0 2.1 2 0 0 2 2 2 0 Wall-associated kinase CPT PF07931.12 KLO05829.1 - 0.023 14.6 0.0 0.25 11.2 0.0 2.1 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 KLO05829.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KLO05829.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 KLO05829.1 - 0.16 11.5 0.0 4.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain F-box-like PF12937.7 KLO05832.1 - 1.3e-08 34.6 0.2 4e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO05832.1 - 0.0048 16.7 0.3 0.062 13.2 0.3 2.7 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO05833.1 - 1.8e-05 24.5 0.1 8.8e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 F-box-like MitMem_reg PF13012.6 KLO05833.1 - 0.048 14.1 0.1 0.22 12.0 0.0 2.1 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF4169 PF13770.6 KLO05835.1 - 1.1 9.5 4.8 5.5 7.4 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) DUF4473 PF14747.6 KLO05836.1 - 0.13 12.9 0.1 0.27 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) SLT_L PF14718.6 KLO05837.1 - 0.043 13.9 0.0 0.05 13.7 0.0 1.1 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain MULE PF10551.9 KLO05838.1 - 4.1e-09 36.7 0.0 2.6e-08 34.2 0.0 2.3 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 KLO05838.1 - 0.0012 18.4 0.5 0.0029 17.2 0.5 1.5 1 0 0 1 1 1 1 SWIM zinc finger BChl_A PF02327.17 KLO05838.1 - 0.17 10.7 0.1 0.29 9.9 0.1 1.3 1 0 0 1 1 1 0 Bacteriochlorophyll A protein Cauli_VI PF01693.16 KLO05839.1 - 0.0015 18.8 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Peptidase_S9 PF00326.21 KLO05842.1 - 9.1e-10 38.4 0.5 8.6e-08 31.9 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KLO05842.1 - 8.4e-06 25.2 0.3 2.1e-05 23.9 0.3 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KLO05842.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_L1 PF00687.21 KLO05843.1 - 4e-60 203.0 0.4 4e-60 203.0 0.4 2.1 2 1 1 3 3 3 1 Ribosomal protein L1p/L10e family CCSAP PF15748.5 KLO05843.1 - 7.8 6.6 28.9 15 5.7 28.9 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MFS_1 PF07690.16 KLO05844.1 - 4.6e-17 62.0 42.5 1.9e-16 60.0 40.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_16 PF10294.9 KLO05844.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase DDHD PF02862.17 KLO05845.1 - 1.8e-27 97.0 5.1 3e-26 93.0 0.0 3.2 3 2 0 3 3 3 1 DDHD domain DUF900 PF05990.12 KLO05845.1 - 0.13 11.7 0.1 0.48 9.9 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) GH131_N PF18271.1 KLO05846.1 - 1.1e-62 212.0 0.4 1.4e-62 211.7 0.4 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 KLO05846.1 - 1.9e-12 46.9 10.0 1.9e-12 46.9 10.0 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain DIM PF08194.12 KLO05846.1 - 0.18 12.0 0.1 0.43 10.8 0.1 1.6 1 0 0 1 1 1 0 DIM protein ALAD PF00490.21 KLO05849.1 - 2.9e-121 404.5 0.0 3.5e-121 404.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase ABC_tran PF00005.27 KLO05852.1 - 2.6e-24 86.3 0.0 5.2e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KLO05852.1 - 5.4e-09 35.8 0.7 0.00055 19.4 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KLO05852.1 - 2.2e-05 24.4 0.1 0.00012 22.0 0.0 2.1 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KLO05852.1 - 0.00013 21.8 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO05852.1 - 0.00041 20.6 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KLO05852.1 - 0.0016 18.2 0.1 0.0033 17.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KLO05852.1 - 0.011 16.2 0.1 0.025 15.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KLO05852.1 - 0.014 14.1 0.0 0.26 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KLO05852.1 - 0.023 15.3 0.0 0.095 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain KH_2 PF07650.17 KLO05852.1 - 0.036 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 KH domain AAA_30 PF13604.6 KLO05852.1 - 0.039 13.7 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KLO05852.1 - 0.053 12.7 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 KLO05852.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KLO05852.1 - 0.14 11.3 0.1 0.24 10.5 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain TniB PF05621.11 KLO05852.1 - 0.15 11.4 0.1 0.83 9.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein SRP54 PF00448.22 KLO05852.1 - 0.16 11.6 0.8 0.69 9.5 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NIF PF03031.18 KLO05854.1 - 8.1e-39 132.9 0.0 1.1e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase adh_short PF00106.25 KLO05855.1 - 0.00015 21.3 0.0 0.00033 20.2 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KLO05855.1 - 0.0024 17.8 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.18 KLO05856.1 - 0.00025 21.1 12.0 0.00035 20.6 12.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2771 PF10969.8 KLO05856.1 - 0.2 11.7 1.2 0.2 11.7 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) Zn_clus PF00172.18 KLO05858.1 - 2e-07 31.0 26.9 0.00026 21.0 11.3 2.1 1 1 1 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain RNase_T PF00929.24 KLO05859.1 - 1.6e-11 45.0 0.0 3.1e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 Exonuclease Mito_carr PF00153.27 KLO05860.1 - 8.7e-58 192.3 1.4 1.6e-20 72.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CFEM PF05730.11 KLO05863.1 - 1e-06 28.7 8.7 1.7e-06 28.0 8.7 1.4 1 0 0 1 1 1 1 CFEM domain SPX PF03105.19 KLO05863.1 - 0.61 9.9 3.5 0.81 9.5 3.5 1.1 1 0 0 1 1 1 0 SPX domain Sec6 PF06046.13 KLO05867.1 - 1.1e-143 479.6 6.1 1.1e-143 479.6 6.1 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KLO05867.1 - 0.0047 15.9 3.9 0.02 13.9 1.4 2.4 2 0 0 2 2 2 1 Vps53-like, N-terminal SKA2 PF16740.5 KLO05867.1 - 0.065 13.0 5.1 0.79 9.5 0.5 3.7 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Vps51 PF08700.11 KLO05867.1 - 0.62 10.2 5.7 1.1 9.4 0.5 3.7 2 1 0 2 2 2 0 Vps51/Vps67 DUF3348 PF11828.8 KLO05867.1 - 1.9 8.1 8.4 1.1 8.9 0.3 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF3348) NPV_P10 PF05531.12 KLO05867.1 - 3.6 8.1 6.0 10 6.6 1.1 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF5344 PF17279.2 KLO05867.1 - 8.1 7.1 7.5 7 7.3 1.9 3.7 3 1 0 3 3 3 0 Family of unknown function (DUF5344) CN_hydrolase PF00795.22 KLO05868.1 - 5e-38 130.9 0.0 9e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KLO05868.1 - 1.5e-22 79.9 0.0 7.9e-22 77.6 0.0 2.0 1 1 0 1 1 1 1 NAD synthase F-box PF00646.33 KLO05869.1 - 1.9e-05 24.4 0.4 6.9e-05 22.6 0.4 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO05869.1 - 0.00034 20.5 0.2 0.00082 19.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KLO05869.1 - 0.061 13.2 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 F-box Focal_AT PF03623.13 KLO05870.1 - 0.033 14.2 1.2 0.05 13.6 0.2 1.8 2 0 0 2 2 2 0 Focal adhesion targeting region DEAD PF00270.29 KLO05871.1 - 7.5e-38 130.0 0.0 1.1e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO05871.1 - 1.9e-29 102.3 0.0 1.1e-28 99.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO05871.1 - 9.5e-06 25.7 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 KLO05871.1 - 0.00098 17.5 0.1 0.0014 17.0 0.1 1.2 1 0 0 1 1 1 1 CDC45-like protein Apt1 PF10351.9 KLO05871.1 - 0.086 11.7 3.1 0.071 12.0 0.6 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain CMS1 PF14617.6 KLO05871.1 - 0.18 11.1 0.0 0.18 11.1 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Spt20 PF12090.8 KLO05871.1 - 0.82 9.2 3.8 1.4 8.5 3.8 1.2 1 0 0 1 1 1 0 Spt20 family Pkinase_fungal PF17667.1 KLO05872.1 - 1.4e-85 287.5 0.0 2e-85 287.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO05872.1 - 0.0002 20.8 0.1 0.27 10.5 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KLO05872.1 - 0.041 13.2 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain STE3 PF02076.15 KLO05873.1 - 7.7e-70 235.4 10.8 9e-70 235.2 10.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor RicinB_lectin_2 PF14200.6 KLO05874.1 - 0.001 19.8 3.2 0.13 13.0 1.7 2.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Inhibitor_I66 PF16850.5 KLO05876.1 - 8.4e-05 22.5 1.4 0.00043 20.2 0.5 2.5 3 0 0 3 3 3 1 Peptidase inhibitor I66 RicinB_lectin_2 PF14200.6 KLO05876.1 - 8.7e-05 23.2 0.3 0.00043 20.9 0.2 2.3 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_43 PF04616.14 KLO05877.1 - 3.6e-37 128.3 0.6 5.8e-37 127.6 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 adh_short_C2 PF13561.6 KLO05878.1 - 2.1e-47 161.7 0.1 2.5e-47 161.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO05878.1 - 1.7e-44 151.6 3.3 2.2e-44 151.2 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO05878.1 - 1.5e-08 34.8 1.0 2.3e-08 34.2 1.0 1.3 1 1 0 1 1 1 1 KR domain B12-binding PF02310.19 KLO05878.1 - 0.038 14.0 1.0 0.075 13.1 0.9 1.7 1 1 0 1 1 1 0 B12 binding domain ATP-cone PF03477.16 KLO05878.1 - 0.043 14.4 0.3 0.09 13.4 0.3 1.5 1 0 0 1 1 1 0 ATP cone domain YjeF_N PF03853.15 KLO05878.1 - 0.05 13.5 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 YjeF-related protein N-terminus Enoyl_reductase PF12241.8 KLO05878.1 - 0.084 12.2 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Toxin_36 PF10550.9 KLO05878.1 - 0.088 14.2 0.6 0.19 13.2 0.6 1.6 1 0 0 1 1 1 0 Conantokin-G mollusc-toxin adh_short_C2 PF13561.6 KLO05879.1 - 4.1e-57 193.4 0.7 4.7e-57 193.2 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO05879.1 - 1.9e-53 180.9 4.5 2.4e-53 180.5 4.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO05879.1 - 6.9e-11 42.4 1.7 1.2e-10 41.6 1.7 1.4 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KLO05879.1 - 0.036 13.1 0.3 0.045 12.7 0.3 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Luteo_P1-P2 PF08467.10 KLO05879.1 - 0.072 12.3 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase Epimerase PF01370.21 KLO05879.1 - 0.15 11.5 0.5 0.52 9.7 0.5 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Prenyltransf PF01255.19 KLO05879.1 - 0.16 11.4 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase GST_N_3 PF13417.6 KLO05880.1 - 3.8e-09 36.8 0.0 6.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO05880.1 - 6.3e-07 29.6 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO05880.1 - 1.1e-06 28.5 0.0 2.9e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KLO05880.1 - 2.6e-06 27.7 0.0 7.6e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO05880.1 - 7.2e-06 26.1 0.0 6.1e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO05880.1 - 0.0002 21.5 0.0 0.00052 20.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KLO05880.1 - 0.025 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin GST_C_5 PF16865.5 KLO05880.1 - 0.028 15.0 0.0 0.048 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KLO05880.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF5063 PF16702.5 KLO05880.1 - 0.16 12.3 0.0 0.66 10.3 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5063) DEAD PF00270.29 KLO05881.1 - 3.2e-38 131.2 0.0 5.9e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO05881.1 - 1.6e-23 83.2 0.1 1.6e-20 73.5 0.1 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO05881.1 - 0.026 14.5 0.0 0.29 11.1 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit p450 PF00067.22 KLO05882.1 - 1.5e-42 145.9 0.0 2.2e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CTP_synth_N PF06418.14 KLO05883.1 - 7.3e-121 402.5 0.4 9.3e-121 402.2 0.4 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KLO05883.1 - 6e-54 182.7 0.0 1e-53 181.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KLO05883.1 - 0.046 13.5 0.1 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 Peptidase C26 adh_short PF00106.25 KLO05884.1 - 6.2e-53 179.2 2.1 8.4e-53 178.7 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO05884.1 - 7e-53 179.6 0.7 9e-53 179.2 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO05884.1 - 1.5e-12 47.8 2.4 2.1e-12 47.3 1.9 1.5 2 0 0 2 2 2 1 KR domain VASP_tetra PF08776.11 KLO05884.1 - 0.03 13.9 0.1 0.074 12.6 0.1 1.6 1 0 0 1 1 1 0 VASP tetramerisation domain HHH_5 PF14520.6 KLO05884.1 - 0.071 13.7 3.4 0.41 11.3 0.5 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain 3HCDH_N PF02737.18 KLO05884.1 - 0.095 12.6 0.8 0.18 11.6 0.8 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2587 PF10759.9 KLO05884.1 - 0.15 11.6 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) adh_short_C2 PF13561.6 KLO05885.1 - 2.2e-57 194.3 4.6 2.8e-57 194.0 4.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO05885.1 - 2.1e-54 183.9 7.3 2.6e-54 183.7 7.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO05885.1 - 4.7e-13 49.4 1.1 8e-13 48.7 1.1 1.4 1 1 0 1 1 1 1 KR domain DUF134 PF02001.16 KLO05885.1 - 0.034 14.7 0.1 0.09 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF134 Prenyltransf PF01255.19 KLO05885.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase LytR_C PF13399.6 KLO05885.1 - 0.46 11.5 3.4 2.5 9.2 0.3 2.2 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator adh_short_C2 PF13561.6 KLO05886.1 - 6.2e-55 186.3 2.4 7.4e-55 186.0 2.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO05886.1 - 7.2e-52 175.7 3.0 7.6e-52 175.6 2.5 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO05886.1 - 9.9e-12 45.1 2.7 1.4e-11 44.6 1.6 1.7 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 KLO05886.1 - 6.4e-05 22.1 0.5 9.6e-05 21.5 0.5 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family B12-binding PF02310.19 KLO05886.1 - 0.0041 17.1 0.3 0.0064 16.5 0.3 1.3 1 0 0 1 1 1 1 B12 binding domain Epimerase PF01370.21 KLO05886.1 - 0.027 13.9 0.8 0.11 12.0 0.8 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RuvC PF02075.17 KLO05886.1 - 0.031 14.1 0.6 8.3 6.3 0.1 2.5 1 1 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC DHH PF01368.20 KLO05887.1 - 0.0082 16.4 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 DHH family LPD5 PF18799.1 KLO05889.1 - 0.042 14.3 0.4 0.1 13.0 0.4 1.6 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 DUF5389 PF17364.2 KLO05890.1 - 0.0028 17.7 0.8 0.0047 16.9 0.8 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5389) ubiquitin PF00240.23 KLO05890.1 - 0.01 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Tetraspanin PF00335.20 KLO05893.1 - 7.7e-08 32.3 6.9 1e-07 32.0 6.9 1.1 1 0 0 1 1 1 1 Tetraspanin family CDT1_C PF16679.5 KLO05894.1 - 0.1 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain DUF5553 PF17707.1 KLO05894.1 - 0.63 9.4 5.0 0.54 9.7 0.4 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5553) Myb_DNA-bind_3 PF12776.7 KLO05895.1 - 0.0026 18.7 0.0 0.0064 17.5 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF1713 PF08213.11 KLO05896.1 - 0.0056 16.6 0.7 0.0099 15.8 0.7 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) WSN PF02206.18 KLO05896.1 - 0.031 14.2 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function tRNA-synt_2d PF01409.20 KLO05897.1 - 1.6e-46 158.8 0.1 3.9e-27 95.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KLO05897.1 - 2.2e-24 85.7 0.0 5.1e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain RAI16-like PF10257.9 KLO05901.1 - 1.9e-62 211.2 0.0 3.5e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Peroxin-13_N PF04088.13 KLO05902.1 - 1.3e-44 151.9 0.1 2.3e-44 151.2 0.1 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 KLO05902.1 - 2.6e-10 39.8 1.9 0.00041 19.9 1.7 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KLO05902.1 - 7.1e-10 38.4 0.0 1.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KLO05902.1 - 2.6e-07 30.4 0.1 4.8e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Mucin PF01456.17 KLO05902.1 - 1.2 9.1 15.5 2.3 8.2 15.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Zn_clus PF00172.18 KLO05903.1 - 2.4e-06 27.6 6.5 4.2e-06 26.8 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop16 PF09420.10 KLO05904.1 - 7.8e-52 176.4 0.2 1e-51 176.0 0.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Lipid_DES PF08557.10 KLO05904.1 - 0.055 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) QCR10 PF09796.9 KLO05905.1 - 2e-18 66.2 0.1 2.2e-18 66.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DNA_pol_lambd_f PF10391.9 KLO05905.1 - 0.35 10.7 0.1 0.35 10.7 0.1 1.5 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda HAD_2 PF13419.6 KLO05906.1 - 2e-06 28.0 0.0 8.1e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO05906.1 - 5.7e-05 23.1 0.0 0.0017 18.4 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KLO05906.1 - 0.0084 16.4 0.0 0.024 14.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase His_Phos_2 PF00328.22 KLO05907.1 - 2.7e-52 178.4 0.0 3.7e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SGTA_dimer PF16546.5 KLO05908.1 - 0.11 12.3 0.1 0.19 11.5 0.0 1.4 2 0 0 2 2 2 0 Homodimerisation domain of SGTA ParG PF09274.10 KLO05911.1 - 0.026 14.7 0.0 4.5 7.5 0.0 2.5 2 0 0 2 2 2 0 ParG RMI1_N PF08585.12 KLO05911.1 - 0.063 13.0 0.2 0.18 11.5 0.2 1.7 1 0 0 1 1 1 0 RecQ mediated genome instability protein SlyX PF04102.12 KLO05911.1 - 0.15 12.7 0.9 3.6 8.3 0.2 2.7 2 0 0 2 2 2 0 SlyX ABC2_membrane PF01061.24 KLO05912.1 - 2.8e-74 249.1 65.1 2e-38 132.0 19.7 3.7 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KLO05912.1 - 2e-32 110.9 8.7 1.9e-27 95.0 0.0 3.2 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 KLO05912.1 - 4.2e-28 98.6 0.0 3e-14 53.7 0.0 2.7 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KLO05912.1 - 1.2e-11 45.1 0.1 3.2e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KLO05912.1 - 0.0046 16.1 45.8 0.0097 15.0 19.6 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KLO05912.1 - 0.0055 17.1 0.1 1.5 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KLO05912.1 - 0.0097 15.8 0.3 0.13 12.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KLO05912.1 - 0.072 13.4 0.2 4.7 7.5 0.0 3.1 2 1 0 2 2 2 0 AAA domain Hist_deacetyl PF00850.19 KLO05914.1 - 3.3e-80 269.9 0.0 4.1e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain R3H PF01424.22 KLO05914.1 - 1.9 8.5 4.6 4.4 7.4 0.8 2.4 2 0 0 2 2 2 0 R3H domain Spt5-NGN PF03439.13 KLO05915.1 - 7.8e-09 35.3 0.0 1.7e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KLO05915.1 - 5.5e-08 32.5 18.6 0.0009 19.1 0.1 5.6 6 0 0 6 6 6 3 KOW motif Harakiri PF15196.6 KLO05915.1 - 0.029 14.8 0.2 0.11 13.0 0.2 1.9 1 0 0 1 1 1 0 Activator of apoptosis harakiri Pyridoxal_deC PF00282.19 KLO05917.1 - 6.2e-66 222.6 0.0 9.2e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain dCache_3 PF14827.6 KLO05917.1 - 0.093 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Aminotran_5 PF00266.19 KLO05917.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Snurportin1 PF11538.8 KLO05918.1 - 0.023 14.9 2.4 0.023 14.9 2.4 2.2 2 0 0 2 2 2 0 Snurportin1 MatE PF01554.18 KLO05919.1 - 2.4e-46 157.3 19.7 4.1e-26 91.6 6.8 3.0 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 KLO05919.1 - 1.6e-07 31.5 9.8 1.6e-07 31.5 9.8 3.6 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Bac_surface_Ag PF01103.23 KLO05920.1 - 8e-39 134.0 0.0 1.1e-38 133.6 0.0 1.2 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 KLO05920.1 - 0.17 12.5 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 Surface antigen variable number repeat Alpha-L-AF_C PF06964.12 KLO05922.1 - 4.9e-36 124.4 0.2 1.2e-35 123.2 0.1 1.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KLO05922.1 - 0.032 14.5 0.4 0.073 13.3 0.4 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain LSM PF01423.22 KLO05923.1 - 4.3e-08 32.7 0.0 5.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KLO05923.1 - 0.00081 19.5 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain CBFD_NFYB_HMF PF00808.23 KLO05925.1 - 1.3e-13 51.0 3.6 2.2e-13 50.2 3.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KLO05925.1 - 2e-08 34.6 4.8 2.6e-08 34.3 4.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KLO05925.1 - 0.00052 20.1 0.1 0.0007 19.7 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold LETM1 PF07766.13 KLO05925.1 - 0.077 12.3 0.5 0.11 11.8 0.3 1.4 1 1 0 1 1 1 0 LETM1-like protein Na_Ca_ex PF01699.24 KLO05926.1 - 1.2e-13 51.3 27.3 1.4e-08 34.9 6.9 3.9 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KLO05926.1 - 1.2e-11 45.2 14.4 1.2e-11 45.2 14.4 3.9 2 0 0 2 2 2 1 Inner membrane component domain DUF4131 PF13567.6 KLO05926.1 - 2.2 7.9 7.7 31 4.2 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) MMS1_N PF10433.9 KLO05927.1 - 7e-70 236.0 0.0 1.2e-69 235.2 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KLO05927.1 - 3.9e-35 121.7 0.0 3.1e-34 118.7 0.0 2.5 2 1 0 2 2 2 1 CPSF A subunit region BrnT_toxin PF04365.13 KLO05927.1 - 0.039 14.3 0.0 0.57 10.5 0.0 2.9 3 0 0 3 3 3 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system GH131_N PF18271.1 KLO05929.1 - 2.3e-82 276.5 0.1 2.6e-82 276.3 0.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 KLO05929.1 - 0.019 14.8 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase Laminin_G_2 PF02210.24 KLO05929.1 - 0.08 13.5 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain Yae1_N PF09811.9 KLO05930.1 - 2e-09 37.0 4.6 3.8e-09 36.1 4.6 1.5 1 1 0 1 1 1 1 Essential protein Yae1, N terminal SET PF00856.28 KLO05931.1 - 1.2e-09 38.7 0.0 6.5e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 SET domain HIT PF01230.23 KLO05932.1 - 9.8e-21 74.3 0.1 1.9e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KLO05932.1 - 7.8e-13 48.9 0.0 1.1e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KLO05932.1 - 1.1e-06 28.5 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CDH PF02611.15 KLO05932.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase XPG_I PF00867.18 KLO05933.1 - 1.4e-17 63.8 0.0 3e-17 62.7 0.0 1.6 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KLO05933.1 - 2.1e-05 24.9 0.0 4.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain DUF3432 PF11914.8 KLO05933.1 - 0.0091 16.2 0.1 0.016 15.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3432) XPG_I_2 PF12813.7 KLO05933.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 XPG domain containing Phage_integrase PF00589.22 KLO05934.1 - 0.062 13.1 0.0 5.8 6.7 0.1 2.2 2 0 0 2 2 2 0 Phage integrase family SAP PF02037.27 KLO05935.1 - 0.00015 21.4 0.6 0.00051 19.7 0.0 2.1 2 0 0 2 2 2 1 SAP domain S4_2 PF13275.6 KLO05935.1 - 0.004 16.9 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain TT1725 PF18324.1 KLO05935.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Hypothetical protein TT1725 HrpB2 PF09487.10 KLO05935.1 - 0.32 11.4 2.7 0.88 10.0 0.1 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB2) Cyclin PF08613.11 KLO05937.1 - 4.3e-05 23.9 0.0 4.3e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KLO05937.1 - 0.0014 18.3 0.0 0.0015 18.2 0.0 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain PBP1_TM PF14812.6 KLO05938.1 - 0.074 13.4 4.1 0.27 11.6 4.1 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PHD PF00628.29 KLO05938.1 - 1.8 8.5 8.3 0.071 13.0 2.2 1.8 2 0 0 2 2 2 0 PHD-finger Erf4 PF10256.9 KLO05944.1 - 0.0036 17.4 0.0 0.006 16.7 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Acetyltransf_1 PF00583.25 KLO05945.1 - 2.8e-07 30.8 0.1 4.2e-07 30.2 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KLO05945.1 - 9.5e-07 28.7 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KLO05945.1 - 6.4e-06 26.5 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO05945.1 - 9.2e-06 25.6 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KLO05945.1 - 0.0035 17.4 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KLO05945.1 - 0.0055 17.4 0.0 0.013 16.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CIAPIN1 PF05093.13 KLO05946.1 - 1.7e-26 92.6 15.6 4.8e-19 68.7 3.5 2.0 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis p450 PF00067.22 KLO05947.1 - 1.1e-63 215.7 0.0 1.3e-63 215.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CIAPIN1 PF05093.13 KLO05949.1 - 1.2e-31 109.1 3.3 2e-31 108.5 3.3 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KLO05949.1 - 3.4e-07 30.6 0.0 4.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Retinal PF15449.6 KLO05949.1 - 0.7 7.6 6.3 0.87 7.3 6.3 1.1 1 0 0 1 1 1 0 Retinal protein Forkhead PF00250.18 KLO05950.1 - 9.1e-31 106.0 0.0 1.5e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain AIM3 PF17096.5 KLO05950.1 - 0.24 12.4 2.1 0.53 11.2 2.1 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 zf-HIT PF04438.16 KLO05951.1 - 6.1e-08 32.4 10.7 1e-07 31.7 10.7 1.3 1 0 0 1 1 1 1 HIT zinc finger Med18 PF09637.10 KLO05952.1 - 1.4e-07 31.7 0.0 2.3e-06 27.6 0.0 2.0 1 1 1 2 2 2 1 Med18 protein YARHG PF13308.6 KLO05952.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 YARHG domain p450 PF00067.22 KLO05954.1 - 2.5e-58 198.0 0.0 3e-32 112.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 His_Phos_2 PF00328.22 KLO05954.1 - 0.075 12.4 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) p450 PF00067.22 KLO05955.1 - 1.4e-48 165.8 0.0 4.2e-46 157.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KLO05956.1 - 2.3e-10 39.9 0.0 2.5e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SDA1 PF05285.12 KLO05957.1 - 0.029 13.8 8.3 0.038 13.4 8.3 1.2 1 0 0 1 1 1 0 SDA1 WD40 PF00400.32 KLO05957.1 - 0.084 13.8 0.1 23 6.1 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat CDC45 PF02724.14 KLO05957.1 - 0.64 8.2 3.0 0.7 8.1 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KLO05957.1 - 2.6 7.3 11.3 9 5.5 11.9 1.5 2 0 0 2 2 2 0 BUD22 DPBB_1 PF03330.18 KLO05960.1 - 2.3e-10 40.6 0.1 2.7e-10 40.4 0.1 1.3 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KLO05960.1 - 2.3e-08 33.9 1.1 2.5e-08 33.8 1.1 1.1 1 0 0 1 1 1 1 Barwin family SP2 PF03014.14 KLO05960.1 - 0.036 12.5 0.4 0.037 12.4 0.4 1.0 1 0 0 1 1 1 0 Structural protein 2 zinc_ribbon_2 PF13240.6 KLO05960.1 - 0.04 13.7 0.9 12 5.8 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-Mss51 PF13824.6 KLO05961.1 - 8.9e-23 80.2 11.4 1.6e-22 79.3 11.4 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.6 KLO05961.1 - 0.13 12.6 3.0 0.25 11.7 3.0 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF1438 PF07270.11 KLO05961.1 - 0.43 10.7 2.7 0.38 10.8 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1438) Pex14_N PF04695.13 KLO05961.1 - 2.9 8.5 10.0 0.51 11.0 6.2 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IGPD PF00475.18 KLO05962.1 - 2.1e-63 212.9 0.5 3.3e-63 212.3 0.5 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Glycos_transf_2 PF00535.26 KLO05963.1 - 3.5e-34 118.1 0.0 4.3e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KLO05963.1 - 9.8e-16 58.3 0.0 1.2e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KLO05963.1 - 1.3e-05 24.9 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KLO05963.1 - 0.084 13.4 0.0 0.3 11.6 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 2 Peptidase_M13_N PF05649.13 KLO05964.1 - 3e-104 349.8 0.0 4.2e-104 349.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KLO05964.1 - 9.1e-61 205.0 0.0 1.5e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 DUF1970 PF09301.10 KLO05964.1 - 0.093 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Halogen_Hydrol PF10112.9 KLO05965.1 - 0.06 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein ADK PF00406.22 KLO05966.1 - 2.3e-41 141.4 0.0 2.9e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KLO05966.1 - 3.5e-19 69.6 0.0 1e-18 68.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KLO05966.1 - 2.4e-14 53.0 0.0 3.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 KLO05966.1 - 0.00019 21.6 0.0 0.00043 20.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KLO05966.1 - 0.00025 21.6 0.0 0.00042 20.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 KLO05966.1 - 0.0085 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 KLO05966.1 - 0.052 12.8 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin GPI-anchored PF10342.9 KLO05967.1 - 1.4e-08 35.4 0.4 1.8e-08 35.0 0.4 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 KLO05970.1 - 0.0026 18.5 0.3 0.0049 17.6 0.3 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family APH PF01636.23 KLO05971.1 - 0.00095 19.2 0.0 0.0011 18.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Xan_ur_permease PF00860.20 KLO05972.1 - 8.4e-61 205.8 32.4 4.8e-59 200.0 32.4 2.2 1 1 0 1 1 1 1 Permease family tRNA_lig_CPD PF08302.11 KLO05973.1 - 0.047 13.1 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Pkinase PF00069.25 KLO05974.1 - 3.4e-32 111.8 0.0 4.4e-31 108.2 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05974.1 - 5.4e-19 68.5 0.0 1.5e-18 67.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO05974.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KLO05974.1 - 0.047 13.3 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 KLO05974.1 - 0.12 11.2 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Sporozoite_P67 PF05642.11 KLO05974.1 - 0.14 10.2 0.0 0.19 9.8 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 KLO05974.1 - 0.45 9.8 2.9 0.63 9.3 2.9 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KLO05974.1 - 5.1 7.5 8.7 9.1 6.7 8.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 KLO05974.1 - 7 6.3 7.6 10 5.7 7.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 KLO05975.1 - 1.8e-23 82.4 21.4 3.1e-07 31.0 0.7 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO05975.1 - 6.7e-12 45.5 1.7 0.00067 19.9 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KLO05975.1 - 5.1e-05 23.1 8.5 0.0021 17.9 0.1 4.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KLO05975.1 - 0.00027 20.4 0.6 0.011 15.1 0.0 2.9 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KLO05975.1 - 0.0012 17.6 2.2 0.23 10.0 0.0 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF5570 PF17731.1 KLO05975.1 - 0.0039 17.3 5.2 0.096 12.8 0.1 3.5 2 1 1 3 3 3 1 Family of unknown function (DUF5570) VID27 PF08553.10 KLO05975.1 - 0.011 14.8 0.0 3.1 6.7 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 KLO05975.1 - 0.027 13.4 0.6 4.7 6.1 0.0 3.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KLO05975.1 - 0.24 9.6 0.0 7.8 4.7 0.0 2.1 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Clathrin PF00637.20 KLO05976.1 - 3e-23 82.3 0.1 1.4e-22 80.2 0.1 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 KLO05976.1 - 0.002 18.5 0.1 0.02 15.3 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 WD40 PF00400.32 KLO05976.1 - 0.0038 18.0 0.2 0.014 16.3 0.2 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat zf-RING_2 PF13639.6 KLO05976.1 - 0.0039 17.5 3.7 0.0086 16.4 0.9 2.5 2 0 0 2 2 2 1 Ring finger domain Vps39_1 PF10366.9 KLO05976.1 - 0.019 15.3 0.0 0.087 13.1 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.6 KLO05976.1 - 0.019 14.9 0.7 0.056 13.4 0.7 1.8 1 1 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KLO05976.1 - 0.12 12.1 1.3 0.37 10.5 1.3 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KLO05976.1 - 0.25 11.4 1.7 0.73 9.9 1.7 1.8 1 0 0 1 1 1 0 Zinc-finger zf-RING_UBOX PF13445.6 KLO05976.1 - 8.6 6.5 7.6 0.31 11.1 1.1 2.0 2 0 0 2 2 2 0 RING-type zinc-finger ABC2_membrane PF01061.24 KLO05977.1 - 1.8e-74 249.7 69.1 1.8e-38 132.1 24.8 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KLO05977.1 - 5.8e-38 130.5 0.0 2e-19 70.5 0.0 2.9 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KLO05977.1 - 1.6e-37 127.3 2.8 2.2e-31 107.6 0.5 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KLO05977.1 - 1.4e-19 70.5 0.7 3.3e-19 69.3 0.7 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KLO05977.1 - 1.5e-07 31.5 0.1 3.5e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KLO05977.1 - 2.2e-07 31.4 0.2 0.00088 19.7 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KLO05977.1 - 4.3e-07 30.3 0.4 0.11 12.7 0.2 3.7 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KLO05977.1 - 4.2e-05 23.2 0.1 0.0021 17.7 0.2 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KLO05977.1 - 9.9e-05 22.4 0.2 0.74 9.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.12 KLO05977.1 - 0.00082 19.3 0.1 0.12 12.3 0.1 2.8 3 0 0 3 3 2 1 NACHT domain AAA_29 PF13555.6 KLO05977.1 - 0.00093 18.9 0.2 0.23 11.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KLO05977.1 - 0.0022 17.8 0.5 1.1 8.9 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KLO05977.1 - 0.0022 18.5 0.0 0.26 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KLO05977.1 - 0.015 15.1 0.1 6.3 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KLO05977.1 - 0.023 14.9 0.9 1.6 9.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KLO05977.1 - 0.028 14.4 0.3 0.28 11.2 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KLO05977.1 - 0.033 13.8 1.2 2.2 7.8 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KLO05977.1 - 0.042 13.6 0.1 4.9 6.9 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.19 KLO05977.1 - 0.049 13.1 0.0 0.99 8.8 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KLO05977.1 - 0.066 13.4 0.1 5.4 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KLO05977.1 - 0.079 13.3 0.0 2.9 8.3 0.0 2.7 3 0 0 3 3 2 0 RNA helicase AAA_23 PF13476.6 KLO05977.1 - 0.096 13.2 0.1 0.3 11.5 0.1 1.8 2 0 0 2 2 1 0 AAA domain DUF3464 PF11947.8 KLO05977.1 - 0.11 12.3 0.1 0.31 10.8 0.1 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 AAA PF00004.29 KLO05977.1 - 0.11 12.9 0.1 5.4 7.5 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 KLO05977.1 - 0.14 11.4 0.0 8.5 5.6 0.0 2.2 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.12 KLO05977.1 - 0.19 11.0 3.4 1.2 8.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin Pkinase PF00069.25 KLO05979.1 - 0.00066 19.1 0.0 0.00079 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05979.1 - 0.004 16.5 0.0 0.0046 16.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO05981.1 - 4.7e-13 49.1 0.0 5.3e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO05981.1 - 1.1e-08 34.7 0.0 1.3e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KLO05981.1 - 0.0015 17.6 0.0 0.0017 17.4 0.0 1.0 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 KLO05981.1 - 0.0038 16.8 0.0 0.0054 16.3 0.0 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 KLO05981.1 - 0.013 14.5 0.0 0.015 14.4 0.0 1.0 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KLO05981.1 - 0.028 14.3 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KLO05981.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.0 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.21 KLO05986.1 - 4.4e-52 177.1 0.0 5.2e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box PF00646.33 KLO05987.1 - 5.9e-06 26.0 1.5 1.8e-05 24.5 1.5 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO05987.1 - 0.00024 20.9 1.8 0.00024 20.9 1.8 2.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KLO05987.1 - 0.0021 18.0 0.1 0.0056 16.5 0.1 1.7 1 0 0 1 1 1 1 F-box Tryp_inh PF17983.1 KLO05988.1 - 0.029 14.5 6.9 0.029 14.5 6.9 2.3 2 0 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 Omega-toxin PF06357.11 KLO05988.1 - 0.09 12.6 3.6 0.16 11.8 3.6 1.4 1 0 0 1 1 1 0 Omega-atracotoxin Cytochrom_C_asm PF01578.20 KLO05988.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C assembly protein F-box-like PF12937.7 KLO05989.1 - 0.0009 19.1 1.2 0.0009 19.1 1.2 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO05990.1 - 3e-05 23.8 0.7 8.6e-05 22.4 0.7 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05990.1 - 6.6e-05 22.7 0.7 0.0002 21.2 0.7 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO05991.1 - 0.013 15.4 0.9 0.013 15.4 0.9 2.1 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 KLO05992.1 - 0.00015 21.6 1.5 0.00048 20.0 1.5 1.8 1 1 0 1 1 1 1 F-box-like Metal_CEHH PF14455.6 KLO05992.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted metal binding domain F-box PF00646.33 KLO05992.1 - 0.33 10.9 8.2 1.5 8.8 1.5 3.3 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO05993.1 - 2.3e-07 30.6 2.8 7.7e-07 28.9 2.8 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05993.1 - 0.043 13.7 6.0 0.25 11.3 6.0 2.4 1 1 0 1 1 1 0 F-box domain UPF0220 PF05255.11 KLO05994.1 - 8.9e-53 178.2 0.0 1e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) F-box PF00646.33 KLO05995.1 - 1.8e-05 24.4 1.6 1.8e-05 24.4 1.6 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KLO05995.1 - 0.0001 22.1 0.1 0.00032 20.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO05996.1 - 3.8e-05 23.5 0.3 0.00011 22.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05996.1 - 0.00033 20.4 0.4 0.0012 18.6 0.4 2.0 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KLO05996.1 - 0.021 15.2 5.0 0.23 12.0 0.3 4.5 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KLO05996.1 - 0.14 12.3 5.9 3.7 7.8 0.3 4.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KLO05996.1 - 3.6 8.5 5.3 5 8.1 0.2 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 KLO05996.1 - 5.7 6.8 6.8 1.2 9.0 0.1 3.4 6 0 0 6 6 6 0 Leucine rich repeat F-box-like PF12937.7 KLO05997.1 - 4.1e-06 26.6 0.4 1.8e-05 24.5 0.4 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO05997.1 - 0.00058 19.7 0.2 0.0018 18.1 0.2 1.9 1 0 0 1 1 1 1 F-box domain VCBS PF13517.6 KLO05997.1 - 0.21 12.2 0.1 0.85 10.3 0.0 2.0 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DM4_12 PF07841.13 KLO06000.1 - 0.015 16.0 0.0 0.032 14.9 0.0 1.6 1 0 0 1 1 1 0 DM4/DM12 family Dynactin_p22 PF07426.11 KLO06000.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Dynactin subunit p22 Ku_PK_bind PF08785.11 KLO06000.1 - 0.062 13.4 0.6 0.19 11.9 0.1 1.9 2 0 0 2 2 2 0 Ku C terminal domain like Ribonuc_red_sm PF00268.21 KLO06008.1 - 1.9e-53 181.7 0.1 3.2e-41 141.7 0.1 2.0 1 1 1 2 2 2 2 Ribonucleotide reductase, small chain STE3 PF02076.15 KLO06011.1 - 2.9e-69 233.5 11.5 3.3e-69 233.3 11.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF2157 PF09925.9 KLO06011.1 - 1 9.2 8.0 1.2 8.9 0.2 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) STE3 PF02076.15 KLO06012.1 - 1.5e-63 214.7 13.9 1.7e-63 214.5 13.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor Multi_Drug_Res PF00893.19 KLO06012.1 - 0.19 12.4 0.3 0.19 12.4 0.3 2.5 2 1 0 2 2 2 0 Small Multidrug Resistance protein Mob1_phocein PF03637.17 KLO06014.1 - 9.6e-24 84.3 0.0 1.8e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family STE3 PF02076.15 KLO06015.1 - 1.5e-61 208.2 7.2 5.2e-60 203.1 7.2 2.0 1 1 0 1 1 1 1 Pheromone A receptor DUF872 PF05915.12 KLO06015.1 - 0.05 13.8 0.3 0.12 12.5 0.3 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) STE3 PF02076.15 KLO06016.1 - 1.5e-72 244.2 10.0 1.8e-72 244.0 10.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor 7tm_1 PF00001.21 KLO06016.1 - 0.25 10.7 4.9 2.3 7.5 5.2 2.0 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Phage_holin_3_6 PF07332.11 KLO06016.1 - 0.26 11.3 0.0 0.26 11.3 0.0 2.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III STE3 PF02076.15 KLO06017.1 - 4e-70 236.3 7.6 4.6e-70 236.1 7.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF3040 PF11239.8 KLO06017.1 - 0.18 12.1 5.4 0.35 11.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) 7tm_1 PF00001.21 KLO06017.1 - 3.1 7.0 6.9 21 4.3 6.7 2.0 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) STE3 PF02076.15 KLO06018.1 - 2.4e-72 243.6 10.2 2.8e-72 243.4 10.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor TFIIA_gamma_N PF02268.16 KLO06019.1 - 4.4e-25 87.4 0.1 6.4e-25 86.9 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KLO06019.1 - 5.1e-18 64.9 0.3 8.9e-18 64.2 0.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Scytalone_dh PF02982.14 KLO06019.1 - 0.11 12.2 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase STE3 PF02076.15 KLO06020.1 - 8.5e-75 251.6 8.3 9.6e-75 251.5 8.3 1.0 1 0 0 1 1 1 1 Pheromone A receptor FtsK_4TM PF13491.6 KLO06025.1 - 4.1 7.1 12.9 0.059 13.1 2.7 2.2 1 1 1 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE DUF3328 PF11807.8 KLO06026.1 - 8.6e-13 48.6 3.2 4.1e-12 46.3 3.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) RPA43_OB PF17875.1 KLO06030.1 - 5.1 7.8 7.2 11 6.7 7.2 1.5 1 1 0 1 1 1 0 RPA43 OB domain in RNA Pol I Acetyltransf_7 PF13508.7 KLO06032.1 - 1.3e-12 48.0 0.0 6.8e-12 45.7 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO06032.1 - 6.1e-12 45.6 0.0 1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO06032.1 - 2.8e-11 43.7 0.2 7.2e-11 42.4 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KLO06032.1 - 0.00053 20.1 0.0 0.0018 18.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO06032.1 - 0.0067 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KLO06032.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 KLO06032.1 - 0.022 14.5 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_6 PF13480.7 KLO06032.1 - 0.038 14.1 0.1 4.1 7.6 0.0 2.6 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain IN_DBD_C PF00552.21 KLO06032.1 - 0.09 12.1 0.5 0.81 9.0 0.1 2.3 2 0 0 2 2 2 0 Integrase DNA binding domain GNAT_acetyltr_2 PF13718.6 KLO06032.1 - 0.18 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF3328 PF11807.8 KLO06033.1 - 7.6e-16 58.5 0.3 1.5e-15 57.6 0.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PGM_PMM_II PF02879.16 KLO06033.1 - 0.064 13.9 0.0 0.097 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Glyco_trans_2_3 PF13632.6 KLO06036.1 - 1.7e-55 188.0 2.5 4.9e-55 186.5 2.5 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KLO06036.1 - 7.9e-06 25.9 0.1 1.5e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KLO06036.1 - 0.00071 19.4 0.0 0.058 13.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KLO06036.1 - 0.012 15.1 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Plavaka PF18759.1 KLO06038.1 - 6.3e-10 38.8 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Plavaka transposase HTH_38 PF13936.6 KLO06040.1 - 0.035 13.9 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_Tnp_4 PF13359.6 KLO06041.1 - 0.00024 20.8 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KLO06041.1 - 0.00057 19.5 0.0 0.00069 19.3 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 KLO06041.1 - 0.0057 17.0 0.1 0.012 16.0 0.0 1.6 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 KLO06041.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.7 KLO06042.1 - 8.6e-08 33.1 0.2 1.1e-07 32.8 0.2 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KLO06042.1 - 0.00049 20.4 0.2 0.0007 19.9 0.2 1.4 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain KDZ PF18758.1 KLO06045.1 - 2.6e-51 174.4 0.0 4.7e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO06045.1 - 3.9e-37 126.7 0.2 2.3e-36 124.2 0.1 2.3 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases 1-cysPrx_C PF10417.9 KLO06048.1 - 0.031 14.1 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin CDC45 PF02724.14 KLO06048.1 - 0.3 9.3 6.6 0.43 8.8 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.7 KLO06049.1 - 8.2e-10 38.4 1.2 8.2e-10 38.4 1.2 2.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO06049.1 - 0.065 13.1 1.3 1.2 9.1 0.2 2.5 2 0 0 2 2 2 0 F-box domain F-box_5 PF18511.1 KLO06049.1 - 0.11 12.1 0.4 1.6 8.4 0.2 2.2 2 0 0 2 2 2 0 F-box CDC45 PF02724.14 KLO06051.1 - 0.094 11.0 0.1 0.15 10.3 0.1 1.3 1 0 0 1 1 1 0 CDC45-like protein TPR_1 PF00515.28 KLO06052.1 - 2.6e-25 87.1 1.2 0.00036 20.2 0.1 7.9 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KLO06052.1 - 1.8e-24 83.9 11.0 0.0027 17.7 0.3 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat DnaJ PF00226.31 KLO06052.1 - 6.5e-21 74.2 0.1 1.6e-20 72.9 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.6 KLO06052.1 - 1.2e-14 54.7 24.9 2.9e-05 24.6 0.2 5.9 4 2 3 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KLO06052.1 - 1.3e-14 53.5 7.1 0.0051 16.5 0.1 6.5 5 1 1 6 6 6 5 TPR repeat TPR_9 PF13371.6 KLO06052.1 - 1.7e-14 53.7 15.3 3.5e-06 27.1 1.7 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KLO06052.1 - 5.8e-12 45.7 13.9 0.0044 17.3 0.0 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KLO06052.1 - 1.7e-10 40.8 24.9 0.0026 18.4 0.1 7.4 6 3 2 8 8 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KLO06052.1 - 2e-08 33.8 0.0 0.08 13.2 0.0 4.5 4 0 0 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO06052.1 - 4.7e-07 29.9 5.4 0.07 13.4 0.0 4.2 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KLO06052.1 - 2.6e-05 24.6 24.2 0.0096 16.4 0.4 6.1 4 3 2 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KLO06052.1 - 3.5e-05 23.9 5.9 35 5.1 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 KLO06052.1 - 3.8e-05 23.0 11.8 0.1 11.8 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KLO06052.1 - 4.3e-05 23.5 0.8 0.51 10.5 0.1 3.0 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 KLO06052.1 - 6.5e-05 22.3 0.1 0.022 14.2 0.1 3.8 4 0 0 4 4 4 1 SHNi-TPR TPR_6 PF13174.6 KLO06052.1 - 0.00029 21.3 3.2 0.35 11.6 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KLO06052.1 - 0.00029 20.7 6.9 2.3 8.4 0.2 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KLO06052.1 - 0.009 15.5 1.5 3.8 6.8 0.0 3.1 3 0 0 3 3 3 2 Coatomer epsilon subunit TPR_4 PF07721.14 KLO06052.1 - 2.7 8.9 11.9 47 5.0 0.0 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat GMC_oxred_N PF00732.19 KLO06053.1 - 2.7e-58 197.7 0.0 3.5e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO06053.1 - 1.5e-39 135.8 0.0 4e-39 134.4 0.0 1.8 2 0 0 2 2 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KLO06053.1 - 2.9e-07 29.9 0.2 5.7e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KLO06053.1 - 2e-06 27.1 0.4 5e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KLO06053.1 - 3.4e-06 26.5 0.1 6.3e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KLO06053.1 - 3.5e-05 23.9 0.6 0.0001 22.4 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO06053.1 - 6.8e-05 22.6 0.1 0.00016 21.4 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO06053.1 - 0.00091 18.5 0.3 0.0015 17.8 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO06053.1 - 0.006 15.3 0.2 0.0085 14.8 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KLO06053.1 - 0.056 14.0 0.3 0.19 12.3 0.3 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KLO06053.1 - 0.14 12.5 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 KLO06053.1 - 0.14 11.0 0.3 0.2 10.4 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 KLO06053.1 - 0.16 11.0 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A GDI PF00996.18 KLO06053.1 - 0.29 9.6 0.0 0.45 9.0 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor GCS PF03074.16 KLO06054.1 - 0.093 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase Adeno_E4 PF05385.11 KLO06055.1 - 8.1 6.6 8.2 14 5.8 8.2 1.4 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein AAA PF00004.29 KLO06057.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-MYND PF01753.18 KLO06066.1 - 0.00026 21.0 9.8 0.00026 21.0 9.8 1.8 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 KLO06066.1 - 0.7 10.0 4.3 2.2 8.4 4.3 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3860 PF12976.7 KLO06067.1 - 0.044 13.8 0.1 0.084 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) Zn_Tnp_IS91 PF14319.6 KLO06067.1 - 0.082 12.9 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain Filament PF00038.21 KLO06068.1 - 0.063 12.9 0.0 0.073 12.6 0.0 1.1 1 0 0 1 1 1 0 Intermediate filament protein ZapB PF06005.12 KLO06068.1 - 0.077 13.5 0.1 0.14 12.7 0.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DDE_1 PF03184.19 KLO06069.1 - 1.3e-22 80.3 0.3 1.4e-21 77.0 0.3 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO06069.1 - 0.00049 19.9 0.1 0.0031 17.3 0.1 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease LUC7 PF03194.15 KLO06070.1 - 0.039 13.6 0.2 0.064 12.9 0.2 1.2 1 0 0 1 1 1 0 LUC7 N_terminus CDP-OH_P_transf PF01066.21 KLO06071.1 - 4e-18 65.9 0.1 4e-18 65.9 0.1 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Citrate_synt PF00285.21 KLO06072.1 - 0.045 12.8 0.0 0.055 12.5 0.0 1.0 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain DDE_1 PF03184.19 KLO06073.1 - 4e-09 36.4 0.0 2.4e-08 33.8 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO06073.1 - 0.092 12.5 0.0 0.23 11.2 0.0 1.7 1 1 0 1 1 1 0 DDE superfamily endonuclease CcdA PF07362.12 KLO06074.1 - 0.015 15.7 2.0 0.036 14.5 2.0 1.7 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA SUIM_assoc PF16619.5 KLO06074.1 - 0.11 12.6 2.8 1.1 9.4 0.5 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Complex1_49kDa PF00346.19 KLO06075.1 - 2.9e-120 400.4 0.0 3.8e-120 400.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KLO06075.1 - 0.0043 16.0 0.0 0.0063 15.5 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase SMP PF04927.12 KLO06076.1 - 4e-05 24.0 1.8 4e-05 24.0 1.8 2.1 2 0 0 2 2 2 1 Seed maturation protein DUF3211 PF11485.8 KLO06077.1 - 0.11 12.8 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) RTC4 PF14474.6 KLO06079.1 - 1.1e-06 28.8 0.0 2.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain CxC5 PF18718.1 KLO06080.1 - 3.6e-31 107.7 0.7 3.6e-31 107.7 0.7 2.4 2 0 0 2 2 2 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 KLO06080.1 - 7.5e-23 80.6 10.2 7.5e-23 80.6 10.2 2.5 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases Condensin2nSMC PF12422.8 KLO06080.1 - 0.14 12.3 0.2 1.5 9.0 0.0 2.6 4 0 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit TIG_plexin PF17960.1 KLO06080.1 - 0.14 12.2 0.3 0.3 11.1 0.3 1.5 1 0 0 1 1 1 0 TIG domain Pkinase PF00069.25 KLO06082.1 - 3.1e-40 138.2 0.0 4.5e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO06082.1 - 2.6e-38 131.8 0.0 3.9e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO06082.1 - 1.6e-05 23.8 0.1 3.4e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO06082.1 - 0.0041 16.5 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO06082.1 - 0.021 14.4 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KLO06082.1 - 0.032 14.1 0.0 0.11 12.3 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 KLO06082.1 - 0.081 13.1 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Kinase-like PF14531.6 KLO06082.1 - 0.11 11.8 0.1 0.9 8.8 0.1 2.1 1 1 0 1 1 1 0 Kinase-like GSK-3_bind PF05350.12 KLO06083.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Pkinase PF00069.25 KLO06091.1 - 2.1e-40 138.8 0.0 3.2e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO06091.1 - 2.2e-37 128.8 0.0 3e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO06091.1 - 8.1e-06 24.9 0.2 1.6e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KLO06091.1 - 0.011 15.3 0.0 0.053 13.1 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KLO06091.1 - 0.082 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KLO06091.1 - 0.13 11.6 0.0 0.43 9.8 0.0 1.8 1 1 0 1 1 1 0 Kinase-like CAP_N PF01213.19 KLO06092.1 - 7.4 6.0 13.2 0.45 9.9 7.4 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Methyltransf_2 PF00891.18 KLO06094.1 - 5.3e-20 71.6 0.0 1.2e-18 67.2 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation PF08100.11 KLO06094.1 - 0.018 15.1 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain MTS PF05175.14 KLO06094.1 - 0.042 13.4 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KLO06094.1 - 0.043 13.3 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 KLO06094.1 - 0.11 13.3 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain YfdX PF10938.8 KLO06094.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 YfdX protein Methyltransf_2 PF00891.18 KLO06095.1 - 2.1e-24 86.0 0.0 6e-20 71.4 0.0 2.4 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_31 PF13847.6 KLO06095.1 - 0.008 16.0 0.0 0.049 13.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KLO06095.1 - 0.026 14.1 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KLO06095.1 - 0.047 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 KLO06095.1 - 0.14 12.9 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KLO06095.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KLO06095.1 - 0.16 12.7 0.0 0.38 11.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 KLO06097.1 - 3.2e-71 240.5 0.0 3.9e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nop14 PF04147.12 KLO06098.1 - 0.042 12.1 10.8 0.049 11.8 10.8 1.0 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_jaz PF12171.8 KLO06098.1 - 0.34 11.2 2.2 0.55 10.6 2.2 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SDA1 PF05285.12 KLO06098.1 - 5.3 6.4 14.8 6.8 6.0 14.8 1.2 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.25 KLO06099.1 - 5.7e-44 150.5 0.0 1.3e-25 90.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO06099.1 - 4.9e-22 78.4 0.0 1.9e-11 43.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KLO06099.1 - 0.00027 20.4 0.0 0.46 9.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KLO06099.1 - 0.0035 17.3 0.3 0.24 11.3 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF3293 PF11697.8 KLO06100.1 - 0.075 13.5 0.1 0.21 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) TFB6 PF17110.5 KLO06100.1 - 0.078 12.7 0.8 0.69 9.6 0.5 2.4 1 1 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Methyltransf_2 PF00891.18 KLO06101.1 - 1.9e-24 86.1 0.0 7.4e-20 71.1 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain MTS PF05175.14 KLO06101.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KLO06101.1 - 0.14 12.9 0.0 0.45 11.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Mustang PF15682.5 KLO06101.1 - 0.16 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 Ribosomal_L10 PF00466.20 KLO06104.1 - 8.4e-24 83.6 2.4 1.3e-23 83.0 0.3 2.2 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 KLO06104.1 - 4.3e-22 77.9 0.1 8.4e-22 77.0 0.1 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KLO06104.1 - 1.1e-20 73.9 9.4 1.6e-20 73.4 7.0 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein G-alpha PF00503.20 KLO06108.1 - 9.5e-107 357.2 0.0 8.9e-106 354.0 0.0 2.0 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO06108.1 - 1.8e-13 50.3 0.2 2.9e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KLO06108.1 - 0.00081 19.6 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KLO06108.1 - 0.0052 16.2 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 KLO06108.1 - 0.042 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KLO06108.1 - 0.093 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KLO06108.1 - 0.11 12.0 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PHD PF00628.29 KLO06109.1 - 8.5e-08 32.0 7.0 1.6e-07 31.1 7.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KLO06109.1 - 0.0046 16.5 5.2 0.0095 15.5 5.2 1.5 1 0 0 1 1 1 1 PHD-finger BTB PF00651.31 KLO06111.1 - 0.0001 22.5 0.3 0.0018 18.5 0.3 2.4 1 1 0 1 1 1 1 BTB/POZ domain Aldo_ket_red PF00248.21 KLO06113.1 - 1.9e-69 234.1 0.1 2.2e-69 233.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LOH1CR12 PF10158.9 KLO06113.1 - 0.034 14.2 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 Tumour suppressor protein BTB PF00651.31 KLO06114.1 - 2.1e-06 27.9 0.3 8.5e-06 26.0 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain Lipase_3 PF01764.25 KLO06115.1 - 1.6e-10 41.0 0.0 2.4e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) BTB PF00651.31 KLO06116.1 - 0.00028 21.1 0.0 0.00051 20.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF3716 PF12511.8 KLO06116.1 - 0.29 11.2 2.6 0.54 10.3 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) BTB PF00651.31 KLO06118.1 - 3.2e-06 27.4 0.0 7.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO06119.1 - 0.04 14.1 0.1 0.13 12.5 0.1 1.9 1 1 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 KLO06120.1 - 0.0028 17.9 0.1 0.015 15.5 0.1 2.2 1 1 0 1 1 1 1 BTB/POZ domain Lactonase PF10282.9 KLO06120.1 - 0.22 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller BTB PF00651.31 KLO06121.1 - 9.7e-08 32.2 0.4 2.4e-06 27.7 0.1 2.8 3 1 0 3 3 3 1 BTB/POZ domain BTB PF00651.31 KLO06122.1 - 2.5e-08 34.1 0.1 5.1e-07 29.9 0.0 2.6 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO06123.1 - 2.3e-07 31.0 0.8 4.9e-06 26.7 0.2 2.9 2 1 0 2 2 2 1 BTB/POZ domain Lipase_3 PF01764.25 KLO06124.1 - 1.3e-21 77.0 0.0 1.7e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KLO06124.1 - 0.012 16.2 1.5 0.018 15.6 1.4 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Candida_ALS PF05792.13 KLO06125.1 - 1.3 9.6 5.6 1.5 9.4 0.7 2.2 2 0 0 2 2 2 0 Candida agglutinin-like (ALS) F-box-like PF12937.7 KLO06126.1 - 1.4e-07 31.3 1.0 5.7e-07 29.3 0.2 2.4 2 0 0 2 2 2 1 F-box-like WT1 PF02165.15 KLO06126.1 - 0.15 11.3 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Wilm's tumour protein PAW PF04721.17 KLO06132.1 - 0.11 12.2 0.1 0.79 9.5 0.0 2.0 2 0 0 2 2 2 0 PNGase C-terminal domain, mannose-binding module PAW DUF368 PF04018.13 KLO06134.1 - 0.025 14.1 6.2 0.033 13.8 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF368) Ten1_2 PF15490.6 KLO06135.1 - 0.067 12.9 0.1 6.3 6.5 0.0 2.9 1 1 1 2 2 2 0 Telomere-capping, CST complex subunit PIF1 PF05970.14 KLO06136.1 - 1.6e-09 37.5 0.0 1.7e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Sugar_tr PF00083.24 KLO06137.1 - 2.9e-13 49.5 4.0 1.2e-10 40.9 0.8 3.6 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 KLO06137.1 - 0.0011 18.0 5.7 0.015 14.2 2.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily NOT2_3_5 PF04153.18 KLO06137.1 - 0.021 14.9 0.0 0.91 9.6 0.0 2.2 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family Corona_5a PF06336.11 KLO06139.1 - 0.043 13.8 0.4 0.085 12.9 0.4 1.5 1 0 0 1 1 1 0 Coronavirus 5a protein IGF2_C PF08365.11 KLO06139.1 - 0.12 12.4 0.1 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide MSL1_dimer PF16801.5 KLO06139.1 - 0.24 11.2 0.5 0.45 10.3 0.5 1.4 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 Sugar_tr PF00083.24 KLO06141.1 - 3.2e-112 375.7 22.1 3.6e-112 375.5 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO06141.1 - 3.6e-22 78.8 30.4 3.6e-22 78.8 30.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.11 KLO06141.1 - 0.44 10.0 5.2 0.41 10.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PIN_3 PF13470.6 KLO06142.1 - 0.33 11.7 5.5 0.98 10.2 0.5 2.7 2 0 0 2 2 2 0 PIN domain PWWP PF00855.17 KLO06142.1 - 3 8.3 5.4 2.4 8.6 0.2 2.7 2 0 0 2 2 2 0 PWWP domain Presenilin PF01080.17 KLO06142.1 - 9.7 4.8 28.1 0.13 11.0 10.0 2.3 2 0 0 2 2 2 0 Presenilin Plavaka PF18759.1 KLO06143.1 - 9.4e-106 353.7 0.0 1.2e-105 353.4 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF3759 PF12585.8 KLO06145.1 - 8.8e-06 25.7 0.3 1.3e-05 25.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Sugar_tr PF00083.24 KLO06147.1 - 1.3e-111 373.7 19.0 1.5e-111 373.5 19.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO06147.1 - 6.7e-21 74.6 33.9 1.5e-16 60.3 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KLO06147.1 - 0.00089 17.8 1.2 0.0013 17.2 0.3 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Astacin PF01400.24 KLO06148.1 - 0.00029 20.5 0.1 0.0028 17.3 0.1 2.3 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KLO06148.1 - 0.014 15.3 0.5 0.027 14.3 0.5 1.5 1 1 0 1 1 1 0 Matrixin DUF4953 PF16313.5 KLO06148.1 - 0.024 13.9 0.0 0.077 12.2 0.0 1.7 2 0 0 2 2 2 0 Met-zincin FYVE PF01363.21 KLO06149.1 - 0.014 15.5 0.9 0.025 14.7 0.9 1.7 1 1 0 1 1 1 0 FYVE zinc finger SBP PF03110.14 KLO06149.1 - 0.017 15.4 4.4 0.08 13.3 0.2 2.2 1 1 1 2 2 2 0 SBP domain zf-CSL PF05207.13 KLO06149.1 - 0.065 13.0 0.8 0.14 11.9 0.8 1.5 1 0 0 1 1 1 0 CSL zinc finger zf-PHD-like PF15446.6 KLO06149.1 - 0.066 12.8 3.4 0.091 12.4 3.4 1.2 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Thioredoxin_3 PF13192.6 KLO06149.1 - 0.53 10.4 2.4 5.7 7.1 0.7 2.2 1 1 1 2 2 2 0 Thioredoxin domain ThiF PF00899.21 KLO06151.1 - 1.5e-69 234.0 0.0 2.1e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 KLO06151.1 - 8.2e-16 58.7 0.0 3.5e-14 53.3 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 KLO06151.1 - 2.8e-07 31.0 0.0 6.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 KLO06151.1 - 0.013 15.9 0.0 0.068 13.6 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding CPL PF08144.11 KLO06152.1 - 1e-34 119.9 0.9 2.4e-31 109.0 0.0 3.7 3 1 1 4 4 4 2 CPL (NUC119) domain RusA PF05866.11 KLO06152.1 - 0.052 14.1 0.9 0.052 14.1 0.9 2.4 2 0 0 2 2 2 0 Endodeoxyribonuclease RusA DOR PF14839.6 KLO06152.1 - 1.8 8.4 5.8 3.6 7.5 5.8 1.6 1 0 0 1 1 1 0 DOR family ANAPC4_WD40 PF12894.7 KLO06156.1 - 2.1e-11 43.9 0.0 2.6e-06 27.6 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KLO06156.1 - 1.9e-08 34.8 3.2 6.6e-05 23.6 0.2 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat OpuAC PF04069.12 KLO06156.1 - 0.18 11.4 0.1 0.67 9.5 0.0 1.8 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system SDA1 PF05285.12 KLO06158.1 - 3.2 7.1 16.1 5 6.5 16.1 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KLO06158.1 - 8 4.5 15.3 10 4.2 15.3 1.1 1 0 0 1 1 1 0 Nop14-like family Sad1_UNC PF07738.13 KLO06159.1 - 4.1e-25 88.3 0.0 1e-11 45.0 0.0 2.1 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal Sld7_C PF18596.1 KLO06162.1 - 0.048 13.8 0.1 0.069 13.3 0.1 1.3 1 0 0 1 1 1 0 Sld7 C-terminal domain F-box PF00646.33 KLO06163.1 - 0.0027 17.5 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 F-box domain Thg1 PF04446.12 KLO06163.1 - 0.033 14.2 0.4 0.16 12.0 0.1 2.2 2 0 0 2 2 2 0 tRNAHis guanylyltransferase F-box-like PF12937.7 KLO06163.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 F-box-like Glycos_trans_3N PF02885.17 KLO06163.1 - 0.17 11.7 0.0 0.64 9.9 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Slx4 PF09494.10 KLO06164.1 - 0.035 14.1 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Slx4 endonuclease Baculo_PEP_C PF04513.12 KLO06165.1 - 2.6e-06 27.5 24.0 0.9 9.6 0.6 7.9 4 3 4 9 9 9 4 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 KLO06165.1 - 7.2e-06 26.2 15.9 0.023 14.8 0.8 5.5 2 2 2 6 6 6 3 Apolipophorin-III precursor (apoLp-III) ATP-synt_D PF01813.17 KLO06165.1 - 0.0011 18.9 0.2 0.0011 18.9 0.2 4.4 3 1 0 3 3 3 1 ATP synthase subunit D Apolipoprotein PF01442.18 KLO06165.1 - 0.0038 17.1 24.5 0.016 15.1 0.9 5.8 1 1 2 4 4 4 1 Apolipoprotein A1/A4/E domain Vip3A_N PF12495.8 KLO06165.1 - 0.0084 16.0 1.4 21 4.9 0.0 4.5 2 1 2 5 5 5 0 Vegetative insecticide protein 3A N terminal DUF1664 PF07889.12 KLO06165.1 - 0.023 14.7 30.8 1.2 9.2 1.0 7.1 6 2 2 8 8 7 0 Protein of unknown function (DUF1664) KxDL PF10241.9 KLO06165.1 - 0.046 14.0 11.1 8 6.8 0.1 5.6 4 2 1 5 5 5 0 Uncharacterized conserved protein HSR PF03172.13 KLO06165.1 - 0.048 13.8 1.6 0.14 12.3 0.4 2.5 2 0 0 2 2 2 0 HSR domain NPV_P10 PF05531.12 KLO06165.1 - 0.056 13.9 22.3 3.5 8.2 0.1 8.1 7 2 0 8 8 8 0 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.12 KLO06165.1 - 0.13 12.1 6.5 7.3 6.5 0.2 5.1 5 0 0 5 5 4 0 Heat shock factor binding protein 1 ZapB PF06005.12 KLO06165.1 - 0.14 12.6 19.0 0.67 10.4 0.0 6.9 6 1 1 7 7 7 0 Cell division protein ZapB DUF16 PF01519.16 KLO06165.1 - 0.16 12.5 22.5 1.2 9.6 0.5 6.5 2 2 3 5 5 5 0 Protein of unknown function DUF16 DUF948 PF06103.11 KLO06165.1 - 0.19 12.0 18.4 1.5 9.2 0.0 6.9 6 2 0 7 7 6 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.11 KLO06165.1 - 0.56 10.0 0.0 0.56 10.0 0.0 3.6 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Trimer_CC PF08954.11 KLO06165.1 - 1.2 8.8 17.9 16 5.1 0.0 7.3 8 1 0 8 8 8 0 Trimerisation motif Dynamin_M PF01031.20 KLO06165.1 - 1.8 7.7 16.4 0.077 12.2 0.2 4.4 4 1 0 4 4 4 0 Dynamin central region Fib_alpha PF08702.10 KLO06165.1 - 7.2 6.8 23.0 2.4 8.3 0.7 5.8 2 1 2 6 6 6 0 Fibrinogen alpha/beta chain family DEAD PF00270.29 KLO06167.1 - 6e-17 62.0 0.0 1.9e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO06167.1 - 0.00087 19.6 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PrgH PF09480.10 KLO06167.1 - 0.014 14.7 0.0 4.3 6.5 0.0 2.1 1 1 1 2 2 2 0 Type III secretion system protein PrgH-EprH (PrgH) ResIII PF04851.15 KLO06167.1 - 0.032 14.2 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KLO06167.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain zf-C2H2 PF00096.26 KLO06168.1 - 9.6e-06 25.8 12.3 0.011 16.2 0.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO06168.1 - 0.0038 17.9 12.8 0.13 13.2 0.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KLO06168.1 - 0.011 16.2 11.9 1.4 9.4 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zinc_ribbon_4 PF13717.6 KLO06168.1 - 0.18 11.8 1.0 0.33 10.9 1.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain FOXP-CC PF16159.5 KLO06168.1 - 0.47 11.1 4.1 0.26 11.9 1.4 2.0 2 1 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KLO06168.1 - 1.8 8.4 5.4 0.28 11.0 0.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain WD40 PF00400.32 KLO06169.1 - 1.1e-33 114.6 27.9 6.1e-05 23.7 0.1 9.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO06169.1 - 5e-11 42.7 0.3 0.065 13.5 0.0 5.3 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 KLO06169.1 - 1.6e-10 41.4 0.0 0.00011 22.5 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KLO06169.1 - 3.3e-10 40.6 1.0 0.00025 21.5 0.0 3.3 3 0 0 3 3 2 2 AAA ATPase domain AAA PF00004.29 KLO06169.1 - 2.1e-08 34.6 0.0 0.0011 19.4 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KLO06169.1 - 8.6e-08 32.3 9.5 0.0095 15.9 0.0 4.7 4 1 0 4 4 4 2 NACHT domain AAA_18 PF13238.6 KLO06169.1 - 1.3e-07 32.2 0.0 0.0036 17.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 KLO06169.1 - 5.6e-07 29.5 0.0 0.0046 16.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KLO06169.1 - 1.9e-06 27.4 0.0 0.0023 17.2 0.0 3.1 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KLO06169.1 - 2e-06 27.2 0.0 0.009 15.2 0.0 2.8 2 0 0 2 2 2 2 NB-ARC domain AAA_33 PF13671.6 KLO06169.1 - 2.1e-06 28.0 0.1 0.055 13.6 0.1 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KLO06169.1 - 4.4e-05 23.8 0.0 0.61 10.5 0.0 3.0 2 0 0 2 2 2 2 RNA helicase Viral_helicase1 PF01443.18 KLO06169.1 - 6.8e-05 22.7 0.0 0.29 10.8 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KLO06169.1 - 8.5e-05 23.1 0.1 0.42 11.1 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_7 PF12775.7 KLO06169.1 - 0.00011 21.8 0.2 0.64 9.5 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KLO06169.1 - 0.00015 21.1 0.0 0.42 9.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Ploopntkinase3 PF18751.1 KLO06169.1 - 0.00025 21.0 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_14 PF13173.6 KLO06169.1 - 0.00028 20.9 0.1 0.47 10.5 0.0 3.6 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 KLO06169.1 - 0.00041 20.4 0.0 1.1 9.4 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase APS_kinase PF01583.20 KLO06169.1 - 0.0008 19.3 0.9 1.1 9.2 0.1 3.4 3 0 0 3 3 3 1 Adenylylsulphate kinase Rad17 PF03215.15 KLO06169.1 - 0.00094 19.1 0.0 1.8 8.4 0.0 3.2 3 0 0 3 3 2 1 Rad17 P-loop domain Hira PF07569.11 KLO06169.1 - 0.0011 18.8 0.1 0.0092 15.7 0.0 2.5 2 0 0 2 2 2 1 TUP1-like enhancer of split Ge1_WD40 PF16529.5 KLO06169.1 - 0.0012 17.8 1.1 0.19 10.7 0.0 3.7 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_19 PF13245.6 KLO06169.1 - 0.0018 18.6 0.7 0.42 10.9 0.2 3.3 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KLO06169.1 - 0.0021 18.3 0.1 3.3 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KLO06169.1 - 0.0027 17.3 0.1 1.8 8.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KLO06169.1 - 0.0049 16.6 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KLO06169.1 - 0.0057 17.1 0.9 2.9 8.3 0.2 3.0 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 KLO06169.1 - 0.012 15.7 0.9 7.6 6.6 0.1 3.6 3 0 0 3 3 3 0 Adenylate kinase AAA_29 PF13555.6 KLO06169.1 - 0.017 14.9 0.0 7.8 6.3 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KLO06169.1 - 0.023 14.6 0.0 12 5.8 0.0 3.2 3 0 0 3 3 2 0 RsgA GTPase PD40 PF07676.12 KLO06169.1 - 0.032 14.2 0.1 4.5 7.3 0.0 3.2 3 0 0 3 3 2 0 WD40-like Beta Propeller Repeat FtsK_SpoIIIE PF01580.18 KLO06169.1 - 0.059 12.7 0.0 6.7 6.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.14 KLO06169.1 - 0.063 13.3 0.1 18 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Torsin PF06309.11 KLO06169.1 - 0.086 12.9 0.0 8.2 6.5 0.0 2.7 2 0 0 2 2 2 0 Torsin AAA_PrkA PF08298.11 KLO06169.1 - 0.1 11.5 0.0 10 4.9 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain IstB_IS21 PF01695.17 KLO06169.1 - 0.11 12.3 0.0 17 5.1 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein MeaB PF03308.16 KLO06169.1 - 0.12 11.4 0.1 17 4.3 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Sigma54_activ_2 PF14532.6 KLO06169.1 - 0.15 12.2 0.0 36 4.5 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Roc PF08477.13 KLO06169.1 - 0.52 10.5 2.1 35 4.7 0.0 4.1 5 0 0 5 5 3 0 Ras of Complex, Roc, domain of DAPkinase FixS PF03597.15 KLO06170.1 - 0.15 11.8 0.2 0.15 11.8 0.2 2.7 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type SPC25 PF06703.11 KLO06170.1 - 0.22 11.3 0.8 0.45 10.3 0.8 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF3176 PF11374.8 KLO06170.1 - 0.87 9.8 3.6 1.1 9.5 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Vma12 PF11712.8 KLO06170.1 - 2.3 8.3 3.9 4.7 7.3 0.1 2.8 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Adeno_E3_CR2 PF02439.15 KLO06171.1 - 0.0068 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 KLO06171.1 - 0.0077 15.6 0.4 0.032 13.6 0.4 2.1 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4328 PF14219.6 KLO06171.1 - 0.047 13.3 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) RIFIN PF02009.16 KLO06171.1 - 0.091 12.6 2.5 0.17 11.7 2.5 1.4 1 0 0 1 1 1 0 Rifin Syndecan PF01034.20 KLO06171.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain DUF2273 PF10031.9 KLO06171.1 - 0.43 10.6 3.5 0.78 9.8 3.5 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Apt1 PF10351.9 KLO06171.1 - 1 8.1 21.1 0.082 11.7 16.4 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain Suf PF05843.14 KLO06171.1 - 2 8.3 4.7 0.92 9.4 2.3 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SKG6 PF08693.10 KLO06173.1 - 0.042 13.3 0.3 0.095 12.1 0.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GTP_CH_N PF12471.8 KLO06174.1 - 6.4e-89 296.8 0.0 8.7e-89 296.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KLO06174.1 - 1.7e-14 53.7 0.0 2.6e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Rax2 PF12768.7 KLO06176.1 - 0.022 14.2 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Plasmodium_Vir PF05795.11 KLO06176.1 - 0.097 12.1 0.4 0.15 11.5 0.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein BatA PF07584.11 KLO06176.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal SPX PF03105.19 KLO06176.1 - 0.17 11.8 2.9 0.2 11.5 2.9 1.3 1 0 0 1 1 1 0 SPX domain CCDC106 PF15794.5 KLO06176.1 - 9.3 5.9 6.6 14 5.4 6.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PIRT PF15099.6 KLO06177.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Fungal_trans PF04082.18 KLO06178.1 - 2.2e-09 36.7 0.1 5.4e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO06178.1 - 3.4e-07 30.3 10.1 6.5e-07 29.4 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1640 PF07798.11 KLO06178.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) BTB PF00651.31 KLO06185.1 - 0.0099 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Zn_clus PF00172.18 KLO06189.1 - 6.9e-06 26.1 12.3 6.9e-06 26.1 12.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.9 KLO06189.1 - 0.027 14.1 0.2 0.027 14.1 0.2 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 KLO06189.1 - 0.44 10.5 13.9 0.54 10.2 13.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 KLO06189.1 - 0.54 8.7 1.8 0.64 8.5 1.8 1.1 1 0 0 1 1 1 0 Macoilin family zf-MYND PF01753.18 KLO06191.1 - 1.3e-07 31.6 13.2 1.3e-07 31.6 13.2 1.9 2 0 0 2 2 2 1 MYND finger Cpn10 PF00166.21 KLO06192.1 - 9.1e-27 93.0 0.0 1e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF2256 PF10013.9 KLO06195.1 - 0.012 15.7 3.2 0.037 14.1 3.2 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYND PF01753.18 KLO06195.1 - 0.054 13.6 13.0 0.12 12.5 13.0 1.6 1 0 0 1 1 1 0 MYND finger F-box-like PF12937.7 KLO06196.1 - 0.0002 21.2 0.1 0.00073 19.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO06196.1 - 0.014 15.8 1.5 15 6.2 0.1 3.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) zf-MYND PF01753.18 KLO06197.1 - 0.0002 21.4 15.4 0.00054 20.0 15.4 1.8 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 KLO06198.1 - 3.7e-06 26.7 0.0 1.4e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO06198.1 - 0.64 10.5 6.6 33 5.1 0.5 4.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KLO06198.1 - 1.5 8.6 5.6 36 4.2 1.0 3.3 3 0 0 3 3 3 0 Leucine rich repeat Abhydrolase_6 PF12697.7 KLO06199.1 - 1.5e-14 55.1 0.1 1.9e-14 54.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO06199.1 - 2.6e-10 40.4 0.0 4.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO06199.1 - 7.9e-06 25.3 0.0 9.4e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FixS PF03597.15 KLO06200.1 - 0.57 9.9 2.6 1.9 8.2 2.6 1.9 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type F-box-like PF12937.7 KLO06201.1 - 2.8e-06 27.1 2.0 7.8e-06 25.7 2.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO06205.1 - 1.4e-07 31.3 2.6 1.5e-05 24.8 0.1 3.6 3 0 0 3 3 3 2 F-box-like HECA PF15353.6 KLO06208.1 - 0.073 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Headcase protein family homologue Helicase_C PF00271.31 KLO06209.1 - 2.1e-16 60.3 0.0 2.2e-14 53.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO06209.1 - 8.1e-13 48.5 0.0 1.7e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO06209.1 - 1.4e-08 34.9 0.0 2.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 KLO06209.1 - 0.0027 18.4 0.1 0.0063 17.2 0.1 1.6 1 0 0 1 1 1 1 RecQ zinc-binding LSM_int_assoc PF16605.5 KLO06209.1 - 0.13 12.4 0.0 15 5.8 0.0 3.3 3 0 0 3 3 3 0 LSM-interacting associated unstructured F-box-like PF12937.7 KLO06210.1 - 0.00037 20.3 0.1 0.0014 18.5 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO06211.1 - 5.9e-05 22.9 0.1 0.00018 21.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO06211.1 - 0.013 15.3 0.4 0.013 15.3 0.4 3.1 3 0 0 3 3 3 0 F-box domain YabA PF06156.13 KLO06212.1 - 0.033 14.8 1.6 0.046 14.4 1.0 1.5 1 1 0 1 1 1 0 Initiation control protein YabA HALZ PF02183.18 KLO06212.1 - 0.085 13.1 6.4 2.2 8.6 0.8 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper FemAB PF02388.16 KLO06212.1 - 0.19 10.5 1.6 0.22 10.4 1.4 1.2 1 1 0 1 1 1 0 FemAB family DMPK_coil PF08826.10 KLO06212.1 - 1.5 9.0 4.9 12 6.1 2.1 2.3 1 1 1 2 2 2 0 DMPK coiled coil domain like DDE_Tnp_4 PF13359.6 KLO06216.1 - 0.0014 18.3 0.1 0.0024 17.6 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Swi6_N PF18530.1 KLO06216.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Swi6 N-terminal domain DDE_Tnp_4 PF13359.6 KLO06217.1 - 2.2e-14 53.4 0.0 3.3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MRP-S27 PF10037.9 KLO06217.1 - 0.028 13.3 0.1 0.045 12.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Nebulin PF00880.18 KLO06218.1 - 0.21 11.6 1.0 0.51 10.3 1.0 1.6 1 0 0 1 1 1 0 Nebulin repeat zf-RVT PF13966.6 KLO06219.1 - 3.5e-05 24.4 0.1 6.3e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF1593 PF07632.11 KLO06220.1 - 0.00069 19.1 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) KDZ PF18758.1 KLO06221.1 - 7.1e-50 169.7 3.0 7.1e-50 169.7 3.0 1.6 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO06221.1 - 1.6e-24 86.2 0.1 4.8e-24 84.6 0.1 1.9 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KLO06221.1 - 0.014 15.3 0.1 0.038 13.8 0.1 1.9 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO06221.1 - 0.018 15.2 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Cas_Csy4 PF09618.10 KLO06221.1 - 0.65 10.1 2.8 0.39 10.9 0.2 1.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) zf-B_box PF00643.24 KLO06221.1 - 0.73 10.0 4.7 2.1 8.6 4.7 1.8 1 0 0 1 1 1 0 B-box zinc finger KOW PF00467.29 KLO06223.1 - 1.6e-13 50.1 12.9 0.0027 17.6 0.1 6.4 6 0 0 6 6 6 5 KOW motif Spt5-NGN PF03439.13 KLO06223.1 - 4.2e-08 33.0 0.0 8.4e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF3912 PF13051.6 KLO06223.1 - 0.0026 18.0 0.0 1 9.6 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3912) Lectin_C PF00059.21 KLO06226.1 - 0.17 12.6 0.8 0.47 11.2 0.8 1.8 1 1 0 1 1 1 0 Lectin C-type domain ThrE PF06738.12 KLO06228.1 - 3.9e-40 137.7 16.7 3.5e-37 128.1 2.4 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KLO06228.1 - 1e-10 41.9 30.1 3.7e-09 36.8 10.5 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE ThrE PF06738.12 KLO06229.1 - 2.4e-34 118.8 25.6 3.2e-34 118.4 5.3 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter PIRT PF15099.6 KLO06229.1 - 8 6.1 6.1 6 6.5 0.1 3.0 4 0 0 4 4 4 0 Phosphoinositide-interacting protein family Pkinase PF00069.25 KLO06230.1 - 1.6e-25 90.0 0.0 2e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO06230.1 - 5.5e-11 42.2 0.0 7.4e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO06230.1 - 5.7e-07 28.7 0.0 7.7e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 KLO06230.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC1 family MRG PF05712.13 KLO06231.1 - 7.4e-57 191.9 0.2 1.1e-56 191.3 0.2 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KLO06231.1 - 1.7e-10 40.6 0.3 4e-10 39.4 0.3 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KLO06231.1 - 0.026 14.4 0.6 0.06 13.3 0.6 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Mago_nashi PF02792.14 KLO06233.1 - 4.1e-75 250.7 0.9 4.5e-75 250.5 0.9 1.0 1 0 0 1 1 1 1 Mago nashi protein SurE PF01975.17 KLO06234.1 - 1.6e-38 132.5 0.7 2.1e-38 132.1 0.7 1.1 1 0 0 1 1 1 1 Survival protein SurE p450 PF00067.22 KLO06235.1 - 3.6e-24 85.4 0.0 4.4e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lipase_3 PF01764.25 KLO06236.1 - 1.4e-14 54.2 0.0 2.8e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 KLO06236.1 - 0.066 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.22 KLO06237.1 - 8.6e-68 229.1 0.0 1.1e-67 228.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GldM_C PF12080.8 KLO06240.1 - 0.0094 16.2 0.1 0.014 15.6 0.1 1.3 1 1 0 1 1 1 1 GldM C-terminal domain Pil1 PF13805.6 KLO06243.1 - 5.9e-12 45.6 0.0 6e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 DUF4646 PF15496.6 KLO06244.1 - 7e-16 59.0 1.3 2e-13 51.1 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4646) GLE1 PF07817.13 KLO06245.1 - 5.9e-39 133.8 0.0 9.4e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein Ribonuclease_3 PF00636.26 KLO06245.1 - 0.071 13.7 0.2 0.18 12.4 0.2 1.9 1 1 0 1 1 1 0 Ribonuclease III domain ATP11 PF06644.11 KLO06245.1 - 0.35 10.6 10.2 0.59 9.9 10.2 1.3 1 0 0 1 1 1 0 ATP11 protein DUF2151 PF10221.9 KLO06245.1 - 0.5 8.9 7.3 0.65 8.5 7.3 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Dsh_C PF12316.8 KLO06245.1 - 0.66 10.3 3.5 1.5 9.2 3.5 1.5 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Hid1 PF12722.7 KLO06245.1 - 0.8 7.8 3.4 0.96 7.5 3.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 KLO06245.1 - 9.6 4.4 13.8 12 4.0 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_10 PF00331.20 KLO06247.1 - 1.6e-97 326.5 0.1 1.9e-97 326.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KLO06247.1 - 2.6e-13 49.6 11.2 2.6e-13 49.6 11.2 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Sec61_beta PF03911.16 KLO06248.1 - 2.1e-18 66.1 0.6 2.8e-18 65.7 0.6 1.2 1 0 0 1 1 1 1 Sec61beta family Synaptobrevin PF00957.21 KLO06249.1 - 1e-28 99.0 0.1 1.4e-28 98.5 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KLO06249.1 - 5.3e-25 87.3 0.0 1.1e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Fmp27_WPPW PF10359.9 KLO06252.1 - 0.22 10.4 6.0 0.27 10.1 6.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.6 KLO06252.1 - 0.35 10.2 7.0 0.46 9.8 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KLO06252.1 - 0.36 10.9 4.7 0.46 10.5 3.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DEAD PF00270.29 KLO06253.1 - 4.7e-16 59.1 0.0 7.8e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO06253.1 - 6.2e-16 58.7 0.0 5.6e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO06253.1 - 9.5e-07 29.0 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 KLO06253.1 - 0.011 16.5 0.8 0.023 15.4 0.8 1.6 1 0 0 1 1 1 0 RecQ zinc-binding SNF2_N PF00176.23 KLO06253.1 - 0.016 13.9 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain BTB PF00651.31 KLO06255.1 - 0.0018 18.5 0.4 0.006 16.8 0.2 2.0 1 1 1 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO06256.1 - 1.4e-05 25.2 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO06257.1 - 0.00056 20.1 0.0 0.0018 18.5 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain PucR PF07905.11 KLO06257.1 - 0.08 13.2 0.0 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family LTP_2 PF14368.6 KLO06257.1 - 0.16 12.1 0.8 0.27 11.3 0.8 1.3 1 0 0 1 1 1 0 Probable lipid transfer BTB PF00651.31 KLO06258.1 - 2.8e-05 24.3 0.1 0.00015 21.9 0.0 2.2 2 1 0 2 2 2 1 BTB/POZ domain Peptidase_C70 PF12385.8 KLO06258.1 - 0.074 13.0 0.0 0.68 9.9 0.0 2.1 2 0 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 BTB PF00651.31 KLO06259.1 - 0.0009 19.5 0.0 0.0031 17.7 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain DUF3464 PF11947.8 KLO06260.1 - 9.2 6.0 7.7 1.5e+02 2.1 0.0 3.1 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 Plavaka PF18759.1 KLO06261.1 - 1.3e-123 412.4 0.0 1.7e-123 412.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Xrn1_D3 PF18194.1 KLO06262.1 - 0.29 11.3 2.1 9.8 6.4 0.2 2.3 1 1 1 2 2 2 0 Exoribonuclease 1 Domain-3 NST1 PF13945.6 KLO06263.1 - 0.014 15.5 0.3 0.023 14.8 0.3 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Hamartin PF04388.12 KLO06264.1 - 5.2 5.6 14.2 9 4.8 14.2 1.4 1 0 0 1 1 1 0 Hamartin protein DAO_C PF16901.5 KLO06265.1 - 3.1e-45 153.1 0.0 5.3e-45 152.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase DAO PF01266.24 KLO06265.1 - 2.1e-33 116.4 0.0 3.3e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase PSS PF03034.15 KLO06267.1 - 4.1e-114 381.0 14.6 5.3e-114 380.6 14.6 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase Claudin_3 PF06653.11 KLO06267.1 - 0.021 14.7 0.3 0.66 9.9 0.1 2.9 3 0 0 3 3 3 0 Tight junction protein, Claudin-like Zn_clus PF00172.18 KLO06269.1 - 1.3e-08 34.8 7.3 2.8e-08 33.8 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3006 PF11213.8 KLO06269.1 - 0.075 13.3 0.1 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) TANGO2 PF05742.12 KLO06270.1 - 6e-44 151.0 0.0 1.2e-31 110.7 0.0 2.3 2 0 0 2 2 2 2 Transport and Golgi organisation 2 Chlam_PMP PF02415.17 KLO06270.1 - 3.3 8.4 5.9 5.5 7.7 0.1 3.1 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RR_TM4-6 PF06459.12 KLO06270.1 - 4.9 6.9 8.0 9.1 6.0 8.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 KLO06270.1 - 5 5.8 6.1 8.1 5.1 6.1 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Actin PF00022.19 KLO06271.1 - 1e-79 268.1 0.0 1e-78 264.8 0.0 1.9 1 1 0 1 1 1 1 Actin IBN_N PF03810.19 KLO06273.1 - 4.5e-13 48.9 0.2 8.8e-11 41.6 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 KLO06273.1 - 0.0011 19.2 0.3 0.0062 16.7 0.3 2.4 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 Cse1 PF08506.10 KLO06273.1 - 0.0017 17.3 0.0 0.0066 15.3 0.0 2.0 1 0 0 1 1 1 1 Cse1 Cnd1 PF12717.7 KLO06273.1 - 0.0088 16.1 3.1 0.13 12.2 0.3 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KLO06273.1 - 0.022 15.0 0.0 0.15 12.4 0.0 2.6 1 0 0 1 1 1 0 HEAT repeat DUF577 PF04510.12 KLO06273.1 - 0.038 13.9 0.6 0.33 10.9 0.2 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF577) DUF2457 PF10446.9 KLO06273.1 - 1.2 8.2 10.0 1.8 7.6 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 KLO06273.1 - 2.6 6.0 21.6 3 5.8 15.6 2.5 2 0 0 2 2 2 0 DNA polymerase phi zf-C2H2 PF00096.26 KLO06280.1 - 1.6e-08 34.5 10.0 2.2e-06 27.8 2.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KLO06280.1 - 1e-06 28.9 13.1 7.6e-05 23.0 4.2 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KLO06280.1 - 0.0014 19.2 9.0 0.0041 17.8 1.7 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 KLO06280.1 - 0.006 17.2 4.2 0.77 10.4 0.8 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain Rad50_zn_hook PF04423.14 KLO06280.1 - 0.0086 15.9 0.3 0.047 13.5 0.1 2.0 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-C2H2_11 PF16622.5 KLO06280.1 - 0.019 14.7 0.7 0.038 13.8 0.7 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KLO06280.1 - 0.028 14.2 0.7 0.039 13.8 0.1 1.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 KLO06280.1 - 0.035 14.5 3.0 0.19 12.2 0.3 2.4 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KLO06280.1 - 0.14 12.5 5.2 0.21 11.9 5.2 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF2225 PF09986.9 KLO06280.1 - 0.41 10.3 1.9 0.42 10.3 1.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) SNF2_N PF00176.23 KLO06282.1 - 5.7e-07 28.6 0.0 1.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Hypoth_Ymh PF09509.10 KLO06282.1 - 0.096 12.6 0.6 0.47 10.3 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (Hypoth_ymh) Draxin PF15550.6 KLO06283.1 - 1.6 8.5 9.2 4.5 7.0 0.1 2.3 2 0 0 2 2 2 0 Draxin CTD_bind PF04818.13 KLO06285.1 - 0.044 14.6 0.0 7.2 7.5 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase II-binding domain. RE_HaeIII PF09556.10 KLO06285.1 - 0.063 12.3 0.1 0.085 11.9 0.1 1.1 1 0 0 1 1 1 0 HaeIII restriction endonuclease FtsH_ext PF06480.15 KLO06285.1 - 0.1 12.9 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 FtsH Extracellular DUF883 PF05957.13 KLO06285.1 - 0.38 11.4 2.3 0.33 11.6 0.5 1.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) LapA_dom PF06305.11 KLO06286.1 - 0.2 11.5 5.8 0.14 12.0 3.7 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PD40 PF07676.12 KLO06287.1 - 0.17 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat zinc_ribbon_4 PF13717.6 KLO06288.1 - 0.03 14.2 0.2 0.081 12.9 0.2 1.8 1 0 0 1 1 1 0 zinc-ribbon domain DUF4218 PF13960.6 KLO06289.1 - 5e-07 29.3 0.0 7.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF1435 PF07256.12 KLO06289.1 - 0.029 14.4 0.1 0.06 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) Peptidase_C48 PF02902.19 KLO06290.1 - 0.00022 21.2 0.0 0.00022 21.2 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C98 PF15499.6 KLO06291.1 - 0.1 12.0 0.1 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Sad1_UNC PF07738.13 KLO06294.1 - 1.9e-26 92.7 0.0 2.4e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Peptidase_C48 PF02902.19 KLO06295.1 - 1.4e-05 25.1 0.0 3.3e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GerPC PF10737.9 KLO06296.1 - 0.068 13.2 4.4 0.64 10.1 0.3 2.3 2 0 0 2 2 2 0 Spore germination protein GerPC ANAPC4 PF12896.7 KLO06296.1 - 0.088 12.3 0.5 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Baculo_PEP_C PF04513.12 KLO06296.1 - 0.14 12.2 0.5 0.56 10.2 0.0 2.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 KLO06296.1 - 0.47 10.5 6.0 13 5.9 0.4 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein AP3D1 PF06375.11 KLO06297.1 - 1.4 9.2 10.1 0.67 10.2 6.1 2.4 2 1 0 2 2 2 0 AP-3 complex subunit delta-1 HTH_33 PF13592.6 KLO06298.1 - 8.4e-08 31.7 0.1 3.9e-07 29.6 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 KLO06298.1 - 4.3e-07 30.5 0.0 5.5e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 KLO06298.1 - 2.7e-05 23.8 0.2 0.0043 16.8 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KLO06298.1 - 6.1e-05 23.2 0.0 0.00014 22.0 0.0 1.6 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.6 KLO06298.1 - 0.0014 18.6 0.0 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix FUR PF01475.19 KLO06298.1 - 0.02 15.1 0.0 0.63 10.2 0.0 2.1 2 0 0 2 2 2 0 Ferric uptake regulator family Sigma70_r4_2 PF08281.12 KLO06298.1 - 0.02 14.6 0.1 2 8.2 0.0 2.3 2 1 0 2 2 2 0 Sigma-70, region 4 PadR PF03551.14 KLO06298.1 - 0.071 13.1 0.0 1.4 8.9 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family HTH_11 PF08279.12 KLO06298.1 - 0.12 12.4 0.1 13 5.9 0.0 2.4 2 1 0 2 2 2 0 HTH domain TrmB PF01978.19 KLO06298.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_7 PF02796.15 KLO06298.1 - 0.2 11.7 0.8 4.3 7.5 0.0 2.8 3 1 0 3 3 3 0 Helix-turn-helix domain of resolvase p450 PF00067.22 KLO06300.1 - 1.7e-70 238.0 0.0 2.1e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Y_phosphatase PF00102.27 KLO06301.1 - 3.2e-30 105.4 0.0 7.6e-16 58.4 0.0 3.2 3 1 0 3 3 3 3 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KLO06301.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DLH PF01738.18 KLO06302.1 - 3.8e-22 78.9 0.1 4.4e-22 78.7 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Acetyltransf_3 PF13302.7 KLO06303.1 - 1.5e-07 32.1 0.0 2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DLH PF01738.18 KLO06304.1 - 0.0004 20.0 0.0 0.00057 19.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 KLO06305.1 - 1.1e-06 28.4 0.0 1.5e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family KIF1B PF12423.8 KLO06305.1 - 0.18 12.3 0.8 20 5.7 0.0 2.4 2 0 0 2 2 2 0 Kinesin protein 1B Hydrolase_4 PF12146.8 KLO06305.1 - 0.22 10.7 0.0 0.46 9.7 0.0 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 p450 PF00067.22 KLO06307.1 - 5.1e-72 243.1 0.0 6.3e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Adaptin_N PF01602.20 KLO06308.1 - 9.6e-106 354.4 0.3 1.4e-105 353.8 0.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KLO06308.1 - 7.2e-12 45.6 1.2 2.5e-07 30.9 0.0 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KLO06308.1 - 2.6e-09 37.4 3.5 0.0009 19.6 0.0 4.4 5 1 0 5 5 5 2 HEAT repeats HEAT PF02985.22 KLO06308.1 - 6e-06 26.1 0.5 1.6 9.2 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat RTP1_C1 PF10363.9 KLO06308.1 - 0.0016 18.6 1.6 1.1 9.5 0.5 2.8 2 0 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 KLO06308.1 - 0.003 17.9 0.4 4.8 7.6 0.0 3.4 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Proteasom_PSMB PF10508.9 KLO06308.1 - 0.0044 15.6 1.0 0.56 8.6 0.2 2.6 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 KLO06308.1 - 0.0068 16.9 2.7 12 6.5 0.0 4.4 3 1 1 4 4 4 1 HEAT-like repeat Dopey_N PF04118.14 KLO06308.1 - 0.028 13.5 0.1 0.063 12.4 0.1 1.5 1 0 0 1 1 1 0 Dopey, N-terminal Arm PF00514.23 KLO06308.1 - 0.17 12.0 0.4 13 6.0 0.0 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RNA_pol_Rpb4 PF03874.16 KLO06308.1 - 8.2 6.8 6.9 30 5.0 0.0 3.4 4 0 0 4 4 4 0 RNA polymerase Rpb4 Methyltransf_25 PF13649.6 KLO06309.1 - 1.2e-08 35.5 0.0 3.1e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO06309.1 - 4.6e-07 29.7 0.0 1.4e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO06309.1 - 2e-05 24.5 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO06309.1 - 9e-05 23.1 0.0 0.0002 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO06309.1 - 0.038 14.7 0.0 0.1 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KLO06309.1 - 0.062 12.6 0.0 7.7 5.8 0.0 2.6 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family SRP68 PF16969.5 KLO06310.1 - 8.9e-85 285.8 7.7 8.9e-85 285.8 7.7 1.9 2 0 0 2 2 2 2 RNA-binding signal recognition particle 68 ArsA_ATPase PF02374.15 KLO06311.1 - 3.9e-110 367.8 0.3 4.5e-110 367.6 0.3 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KLO06311.1 - 9.2e-14 51.7 0.2 6.8e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KLO06311.1 - 3.3e-12 46.6 0.0 5e-12 46.0 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KLO06311.1 - 1.2e-05 24.9 2.5 5.4e-05 22.8 0.3 2.7 2 2 1 3 3 3 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 KLO06311.1 - 2.6e-05 23.8 0.0 6.1e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 KLO06311.1 - 3.6e-05 23.3 0.0 8.2e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KLO06311.1 - 6.5e-05 22.6 0.8 0.0013 18.4 0.1 2.4 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KLO06311.1 - 0.0074 16.0 0.0 0.024 14.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain VirC1 PF07015.11 KLO06311.1 - 0.0097 15.2 0.1 0.023 14.0 0.1 1.5 1 1 0 1 1 1 1 VirC1 protein PhoH PF02562.16 KLO06311.1 - 0.014 14.9 0.0 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 KLO06311.1 - 0.05 13.2 0.3 0.21 11.1 0.3 2.0 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KLO06311.1 - 0.097 11.9 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin bZIP_1 PF00170.21 KLO06312.1 - 8.9e-11 41.7 12.3 8.9e-11 41.7 12.3 1.8 2 0 0 2 2 2 1 bZIP transcription factor PAP1 PF08601.10 KLO06312.1 - 9.8e-07 28.8 0.2 9.8e-07 28.8 0.2 4.0 3 1 0 3 3 3 1 Transcription factor PAP1 bZIP_2 PF07716.15 KLO06312.1 - 0.00063 19.8 17.7 0.0013 18.7 13.6 2.7 1 1 1 2 2 2 1 Basic region leucine zipper CCDC85 PF10226.9 KLO06312.1 - 0.0017 18.0 0.6 0.0017 18.0 0.6 2.1 2 0 0 2 2 2 1 CCDC85 family TMCO5 PF14992.6 KLO06312.1 - 0.03 13.9 2.8 0.055 13.0 2.8 1.3 1 0 0 1 1 1 0 TMCO5 family SHE3 PF17078.5 KLO06312.1 - 0.21 11.3 8.0 0.42 10.3 7.9 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 XhlA PF10779.9 KLO06312.1 - 1.3 9.3 2.7 2.5 8.4 2.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA PHD PF00628.29 KLO06313.1 - 3.5e-08 33.2 11.1 5.7e-08 32.5 11.1 1.3 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KLO06313.1 - 0.021 15.2 0.2 0.048 14.0 0.2 1.5 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx zf-CW PF07496.15 KLO06313.1 - 0.051 13.6 5.1 0.12 12.5 5.1 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.6 KLO06313.1 - 0.071 12.7 6.0 0.12 11.9 6.0 1.4 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 KLO06313.1 - 0.17 12.0 10.1 0.37 10.9 10.1 1.6 1 0 0 1 1 1 0 PHD-finger DNA_methylase PF00145.17 KLO06314.1 - 4.4e-28 98.6 0.0 5.9e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase eIF-5_eIF-2B PF01873.17 KLO06315.1 - 1.1e-37 128.5 0.0 2.3e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KLO06315.1 - 2.9e-22 78.6 0.1 2.9e-22 78.6 0.1 2.6 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon UME PF08064.13 KLO06315.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 UME (NUC010) domain Thiolase_N PF00108.23 KLO06316.1 - 7.6e-14 51.7 0.0 1.8e-12 47.2 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KLO06316.1 - 5.4e-07 29.3 0.1 2.4e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KLO06316.1 - 5.1e-05 23.0 2.7 0.018 14.6 0.2 2.9 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KLO06316.1 - 0.014 15.2 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Nop14 PF04147.12 KLO06317.1 - 0.075 11.2 8.7 0.1 10.8 8.7 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KLO06317.1 - 1.4 8.2 7.7 0.56 9.5 5.0 1.6 2 0 0 2 2 2 0 NOA36 protein Asp PF00026.23 KLO06318.1 - 1.2e-12 47.9 2.3 1.9e-12 47.3 2.3 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF456 PF04306.13 KLO06318.1 - 0.092 13.0 3.3 0.19 12.0 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Reprolysin_4 PF13583.6 KLO06319.1 - 4.3e-43 147.3 4.2 4.3e-43 147.3 4.2 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KLO06319.1 - 1.5e-42 146.0 8.1 1.5e-42 146.0 8.1 2.7 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KLO06319.1 - 3.3e-42 144.6 4.2 3.3e-42 144.6 4.2 2.5 2 1 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KLO06319.1 - 6e-17 62.2 25.1 6e-17 62.2 25.1 4.7 3 2 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KLO06319.1 - 1.1e-13 51.8 2.0 5.9e-13 49.4 0.0 2.8 2 1 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KLO06319.1 - 1.3e-05 25.2 7.7 1.3e-05 25.2 7.7 3.1 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KLO06319.1 - 0.00071 19.8 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Brr6_like_C_C PF10104.9 KLO06320.1 - 3.4e-45 153.1 1.0 4.5e-45 152.7 1.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain ALMS_repeat PF18727.1 KLO06320.1 - 0.084 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Alstrom syndrome repeat FixQ PF05545.11 KLO06320.1 - 0.29 11.1 0.9 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ CLP_protease PF00574.23 KLO06321.1 - 2.3e-75 252.5 0.0 3.1e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 Clp protease Ribosomal_S21 PF01165.20 KLO06321.1 - 0.034 13.9 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S21 COX7a PF02238.15 KLO06323.1 - 0.14 12.5 1.8 0.53 10.7 1.8 2.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII F-box-like PF12937.7 KLO06324.1 - 2.9e-09 36.7 0.0 7.3e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KLO06324.1 - 0.011 15.7 0.0 0.036 14.0 0.0 1.9 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.33 KLO06324.1 - 0.071 13.0 1.5 5.3 7.0 0.0 2.6 2 0 0 2 2 2 0 F-box domain SNARE_assoc PF09335.11 KLO06327.1 - 2.9e-13 50.4 10.3 6.4e-13 49.2 10.3 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein REV PF00424.18 KLO06329.1 - 0.12 12.4 0.5 0.12 12.4 0.5 1.7 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) F-box-like PF12937.7 KLO06332.1 - 8.3e-07 28.8 0.0 2.1e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO06333.1 - 3.6e-07 30.0 0.1 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO06334.1 - 2.4e-07 30.6 1.2 6.2e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO06334.1 - 0.051 13.5 0.0 0.4 10.6 0.0 2.6 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO06335.1 - 6.9e-09 35.5 0.0 1.8e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO06335.1 - 0.2 12.1 7.2 37 4.9 0.0 5.2 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO06336.1 - 9.6e-08 31.8 0.7 2.1e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO06337.1 - 6.7e-07 29.1 0.0 6.7e-07 29.1 0.0 2.7 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 KLO06337.1 - 0.031 14.1 3.4 0.047 13.6 0.0 3.1 3 0 0 3 3 3 0 F-box domain TA_inhibitor PF17574.2 KLO06337.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) F-box-like PF12937.7 KLO06338.1 - 6.7e-07 29.1 0.1 3.4e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO06338.1 - 0.14 12.6 0.3 8.5 6.9 0.1 3.6 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO06339.1 - 1.4e-05 24.9 3.4 1.4e-05 24.9 0.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO06339.1 - 0.015 15.2 0.1 0.059 13.3 0.1 2.1 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO06340.1 - 6.1e-05 22.8 0.2 0.00014 21.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO06340.1 - 0.0012 18.6 0.2 0.0037 17.1 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO06341.1 - 5.3e-08 32.6 0.6 5.3e-08 32.6 0.6 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO06341.1 - 0.0018 18.1 0.9 0.0043 16.9 0.1 2.1 2 0 0 2 2 2 1 F-box domain APH PF01636.23 KLO06342.1 - 6.2e-11 42.7 0.0 1.1e-10 41.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family F-box-like PF12937.7 KLO06343.1 - 4.8e-08 32.8 0.3 4.8e-08 32.8 0.3 2.3 3 0 0 3 3 3 1 F-box-like BPL_N PF09825.9 KLO06343.1 - 0.043 12.9 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal F-box PF00646.33 KLO06343.1 - 0.056 13.3 3.4 0.42 10.6 2.4 2.9 2 1 0 2 2 2 0 F-box domain APH PF01636.23 KLO06344.1 - 2.5e-09 37.4 0.0 3.5e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Con-6 PF10346.9 KLO06350.1 - 6.1e-12 45.4 0.1 1e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 Conidiation protein 6 A_deamin PF02137.18 KLO06351.1 - 8.1e-59 199.7 0.0 1e-58 199.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF2838 PF10998.8 KLO06352.1 - 3.4e-42 143.2 8.3 7.2e-42 142.1 8.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) DUF5315 PF17242.2 KLO06352.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) Mt_ATP-synt_D PF05873.12 KLO06353.1 - 3.1e-15 56.3 1.1 3.7e-15 56.1 1.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) 120_Rick_ant PF12574.8 KLO06353.1 - 0.023 13.9 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen Aminotran_3 PF00202.21 KLO06353.1 - 0.14 10.8 1.5 6.9 5.2 0.3 2.2 1 1 1 2 2 2 0 Aminotransferase class-III Cauli_AT PF03233.13 KLO06353.1 - 1.6 8.6 4.5 0.65 9.9 1.7 1.9 2 1 0 2 2 2 0 Aphid transmission protein F-box-like PF12937.7 KLO06354.1 - 3.8e-05 23.5 1.5 3.8e-05 23.5 1.5 2.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KLO06354.1 - 0.013 15.4 0.2 0.029 14.2 0.2 1.6 1 0 0 1 1 1 0 F-box Hexokinase_2 PF03727.16 KLO06355.1 - 2.3e-77 259.7 0.0 3e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KLO06355.1 - 3e-72 242.7 0.0 5e-72 242.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Jnk-SapK_ap_N PF09744.9 KLO06357.1 - 0.0087 16.3 2.6 0.018 15.2 2.6 1.5 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 HALZ PF02183.18 KLO06357.1 - 0.015 15.5 0.3 0.031 14.5 0.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.6 KLO06358.1 - 0.14 12.2 0.1 0.47 10.6 0.1 1.9 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF4666 PF15697.5 KLO06360.1 - 0.24 12.1 0.3 1.3 9.7 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4666) F-box-like PF12937.7 KLO06362.1 - 1.2e-06 28.3 0.3 6.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO06362.1 - 2.2 8.3 5.2 28 4.8 0.1 3.2 3 0 0 3 3 3 0 F-box domain VAPB_antitox PF02697.14 KLO06365.1 - 0.076 13.8 0.1 0.23 12.3 0.1 1.8 2 0 0 2 2 2 0 Putative antitoxin Egh16-like PF11327.8 KLO06366.1 - 4.5e-54 183.7 10.3 4.5e-54 183.7 10.3 1.6 2 0 0 2 2 2 1 Egh16-like virulence factor I-set PF07679.16 KLO06366.1 - 0.0039 17.2 0.1 0.0074 16.3 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KLO06366.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KLO06366.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin V-set domain Egh16-like PF11327.8 KLO06367.1 - 4.2e-56 190.3 4.1 4.7e-56 190.1 4.1 1.0 1 0 0 1 1 1 1 Egh16-like virulence factor Oxidored_FMN PF00724.20 KLO06368.1 - 1.3e-69 235.0 0.0 1.6e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family bMG5 PF17972.1 KLO06368.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain F-box-like PF12937.7 KLO06369.1 - 2.6e-07 30.4 0.0 7.1e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO06370.1 - 1.7e-08 34.2 0.1 5.8e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 F-box-like F-box-like PF12937.7 KLO06371.1 - 1.1e-05 25.2 1.0 2.3e-05 24.2 0.1 2.1 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO06372.1 - 5.9e-06 26.1 1.0 1.1e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 F-box-like Pkinase_Tyr PF07714.17 KLO06374.1 - 2.2e-32 112.3 0.0 2.6e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO06374.1 - 8.8e-31 107.2 0.0 1e-30 107.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO06374.1 - 0.073 13.0 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO06374.1 - 0.18 11.1 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 KLO06375.1 - 1.2e-38 132.9 0.0 1.4e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO06375.1 - 3.9e-37 128.1 0.0 4.7e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO06375.1 - 0.00096 18.5 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO06375.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KLO06375.1 - 0.058 13.0 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CAS_CSE1 PF03378.15 KLO06376.1 - 0.011 14.2 0.0 0.02 13.4 0.0 1.4 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Helicase_C PF00271.31 KLO06377.1 - 2.9e-16 59.8 1.0 1.1e-14 54.7 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO06377.1 - 2.1e-08 34.1 0.0 1.2e-07 31.7 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase eIF3_subunit PF08597.10 KLO06377.1 - 0.016 15.1 9.4 0.036 14.0 9.4 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit GBP_C PF02841.14 KLO06377.1 - 0.018 14.5 11.1 0.036 13.5 11.1 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain RecQ_Zn_bind PF16124.5 KLO06377.1 - 0.21 12.4 0.0 0.21 12.4 0.0 2.5 2 1 0 2 2 2 0 RecQ zinc-binding Phage_GPO PF05929.11 KLO06377.1 - 1.1 8.8 14.8 0.056 13.1 9.1 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Pinin_SDK_memA PF04696.13 KLO06377.1 - 5.4 7.1 22.6 21 5.1 22.6 2.0 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Pkinase_Tyr PF07714.17 KLO06381.1 - 1.9e-33 115.8 0.0 2.5e-30 105.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO06381.1 - 5.5e-29 101.3 0.0 2.2e-27 96.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain SWIRM-assoc_1 PF16495.5 KLO06384.1 - 0.0014 18.5 3.8 0.079 12.9 1.2 3.1 2 0 0 2 2 2 1 SWIRM-associated region 1 DUF1664 PF07889.12 KLO06384.1 - 0.0073 16.3 9.8 1.3 9.1 0.3 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1664) ATG16 PF08614.11 KLO06384.1 - 0.089 13.0 15.2 0.054 13.7 1.4 2.8 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Med9 PF07544.13 KLO06384.1 - 0.15 12.2 8.3 0.32 11.1 0.2 3.7 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Filament PF00038.21 KLO06384.1 - 0.37 10.3 20.0 2.9 7.4 20.0 2.1 1 1 0 1 1 1 0 Intermediate filament protein DUF2730 PF10805.8 KLO06384.1 - 0.41 10.8 12.5 1 9.5 0.2 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) DUF745 PF05335.13 KLO06384.1 - 0.47 10.2 8.6 1.2 8.8 1.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF745) DUF4055 PF13264.6 KLO06384.1 - 0.62 10.2 4.8 0.34 11.1 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) Peptidase_S46 PF10459.9 KLO06384.1 - 1 7.9 8.3 1.4 7.5 8.3 1.2 1 0 0 1 1 1 0 Peptidase S46 NPV_P10 PF05531.12 KLO06384.1 - 1.6 9.3 8.1 3.9 8.0 0.3 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein ING PF12998.7 KLO06384.1 - 1.8 9.2 15.4 0.39 11.3 0.9 3.5 2 1 2 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding AMP-binding_C_2 PF14535.6 KLO06384.1 - 1.8 8.9 5.3 0.53 10.6 0.5 2.5 2 1 1 3 3 3 0 AMP-binding enzyme C-terminal domain PDDEXK_6 PF04720.12 KLO06384.1 - 3 7.8 10.4 1.9 8.4 5.0 2.7 3 1 0 3 3 3 0 PDDEXK-like family of unknown function TPR_MLP1_2 PF07926.12 KLO06384.1 - 4.3 7.4 22.1 2.1 8.4 0.9 3.2 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein YtxH PF12732.7 KLO06384.1 - 4.8 7.8 8.2 4.5e+02 1.5 6.1 3.6 2 1 0 2 2 2 0 YtxH-like protein YscO-like PF16789.5 KLO06384.1 - 7.7 6.5 18.1 4.8 7.2 15.0 2.1 1 1 1 2 2 2 0 YscO-like protein EzrA PF06160.12 KLO06386.1 - 0.0042 15.3 0.0 0.1 10.7 0.1 2.0 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 KLO06386.1 - 0.0065 16.5 0.6 0.018 15.1 0.6 1.7 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG17 PF04108.12 KLO06386.1 - 0.07 12.2 1.3 0.45 9.6 0.2 2.1 2 1 1 3 3 3 0 Autophagy protein Apg17 TUDOR PF00567.24 KLO06386.1 - 0.17 11.9 0.0 0.72 9.9 0.0 1.9 1 1 1 2 2 2 0 Tudor domain Zn_clus PF00172.18 KLO06387.1 - 0.0019 18.3 10.5 0.0033 17.5 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tgi2PP PF18250.1 KLO06387.1 - 0.028 14.7 0.1 0.056 13.7 0.1 1.5 1 0 0 1 1 1 0 Effector immunity protein Tgi2PP Zn_clus PF00172.18 KLO06389.1 - 0.26 11.4 14.9 0.47 10.6 14.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Gemini_coat PF00844.18 KLO06393.1 - 0.15 11.5 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family Neuregulin PF02158.15 KLO06395.1 - 0.041 13.2 0.1 0.067 12.5 0.1 1.4 1 1 1 2 2 2 0 Neuregulin intracellular region Nucleo_P87 PF07267.11 KLO06396.1 - 1.5 7.6 9.2 2.5 6.8 9.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nop14 PF04147.12 KLO06396.1 - 2.5 6.2 15.9 3.1 5.9 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KLO06396.1 - 2.9 7.4 13.7 4.6 6.8 13.7 1.2 1 0 0 1 1 1 0 PPP4R2 Roughex PF06020.11 KLO06396.1 - 5.4 6.0 14.8 12 4.9 14.8 1.5 1 0 0 1 1 1 0 Drosophila roughex protein PPTA PF01239.22 KLO06398.1 - 1.4e-39 132.7 11.6 1.2e-07 31.2 0.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat RNA_pol_3_Rpc31 PF11705.8 KLO06399.1 - 1.3e-29 104.1 6.9 1.8e-29 103.6 6.9 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Sugar_tr PF00083.24 KLO06400.1 - 1e-83 281.8 19.9 1.2e-83 281.6 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO06400.1 - 9.8e-28 97.1 36.1 1.2e-22 80.4 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MAM33 PF02330.16 KLO06401.1 - 3.6e-66 223.1 0.0 4.2e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF4918 PF16265.5 KLO06401.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4918) Homoserine_dh PF00742.19 KLO06402.1 - 6.3e-47 159.7 0.0 9.2e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KLO06402.1 - 1.2e-15 58.2 0.0 3.2e-15 56.8 0.0 1.8 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KLO06402.1 - 0.027 14.9 0.0 0.32 11.5 0.0 2.6 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain FA_desaturase PF00487.24 KLO06403.1 - 9.1e-24 84.7 28.2 1.5e-23 84.0 28.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KLO06403.1 - 0.0029 17.8 0.0 0.0052 17.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Abhydrolase_6 PF12697.7 KLO06404.1 - 7.9e-10 39.7 0.6 9.9e-10 39.4 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KLO06404.1 - 0.027 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Cytochrom_B561 PF03188.16 KLO06405.1 - 1.2e-12 48.1 4.5 1.2e-12 48.1 4.5 1.7 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KLO06405.1 - 0.52 10.4 8.7 5 7.3 4.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) SLATT_3 PF18184.1 KLO06405.1 - 1.2 9.3 2.8 1.1 9.4 0.6 1.9 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 DUF2231 PF09990.9 KLO06405.1 - 5.6 7.5 11.1 0.34 11.4 5.2 2.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) MFMR_assoc PF16596.5 KLO06406.1 - 0.0088 16.5 3.6 0.017 15.6 3.6 1.4 1 0 0 1 1 1 1 Disordered region downstream of MFMR Aldo_ket_red PF00248.21 KLO06407.1 - 1.2e-36 126.4 0.0 1.6e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 2-oxoacid_dh PF00198.23 KLO06408.1 - 8.1e-81 270.9 0.0 1.1e-80 270.5 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KLO06408.1 - 2e-19 69.1 1.1 4e-19 68.2 1.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KLO06408.1 - 8e-05 22.4 0.1 0.0069 16.2 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KLO06408.1 - 0.00011 22.8 0.2 0.24 12.1 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 KLO06408.1 - 0.012 15.5 0.3 0.027 14.4 0.3 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF5089 PF17002.5 KLO06408.1 - 0.13 12.1 0.9 0.24 11.3 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) Pneumo_att_G PF05539.11 KLO06408.1 - 1.6 8.2 8.8 2.4 7.7 8.8 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G 7TM-7TMR_HD PF07698.11 KLO06410.1 - 0.053 13.3 0.6 0.084 12.6 0.6 1.3 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase WD40 PF00400.32 KLO06411.1 - 3.5e-54 179.5 29.2 3e-09 37.3 0.1 8.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO06411.1 - 1.2e-23 83.2 0.1 0.0088 16.3 0.0 7.3 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 KLO06411.1 - 3.8e-11 43.4 0.0 0.00014 22.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KLO06411.1 - 2.5e-10 40.5 0.3 2.7e-05 24.1 0.0 3.4 3 1 0 3 3 2 2 NACHT domain AAA_16 PF13191.6 KLO06411.1 - 3.5e-10 40.5 0.0 0.0012 19.2 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.22 KLO06411.1 - 2.3e-09 36.8 0.0 2.5e-06 26.9 0.0 2.9 2 0 0 2 2 2 2 NB-ARC domain AAA PF00004.29 KLO06411.1 - 2.4e-08 34.5 0.0 0.012 16.1 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KLO06411.1 - 1.9e-07 30.6 0.0 0.0087 15.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.6 KLO06411.1 - 3.1e-07 31.0 0.0 0.031 14.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain Ge1_WD40 PF16529.5 KLO06411.1 - 4.7e-07 29.1 0.4 0.4 9.6 0.0 5.1 3 2 4 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RNA_helicase PF00910.22 KLO06411.1 - 1.4e-06 28.6 0.0 0.13 12.6 0.0 3.2 3 0 0 3 3 2 2 RNA helicase APS_kinase PF01583.20 KLO06411.1 - 2.1e-06 27.7 0.0 0.04 13.8 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase Nbas_N PF15492.6 KLO06411.1 - 2.4e-05 23.8 0.6 0.036 13.4 0.0 4.0 3 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal DUF2075 PF09848.9 KLO06411.1 - 5.9e-05 22.5 0.0 0.22 10.7 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) eIF2A PF08662.11 KLO06411.1 - 9.2e-05 22.4 0.0 0.04 13.8 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A AAA_33 PF13671.6 KLO06411.1 - 0.00018 21.7 0.0 0.25 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KLO06411.1 - 0.00041 20.6 0.0 0.32 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KLO06411.1 - 0.0007 19.2 0.1 0.72 9.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 KLO06411.1 - 0.00071 19.6 0.0 0.98 9.3 0.0 2.7 2 1 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 KLO06411.1 - 0.00078 19.2 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KLO06411.1 - 0.0032 17.2 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KLO06411.1 - 0.0042 16.8 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KLO06411.1 - 0.006 17.1 0.0 2.1 8.8 0.0 2.7 2 0 0 2 2 2 1 ABC transporter NTPase_1 PF03266.15 KLO06411.1 - 0.0071 16.3 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 NTPase PD40 PF07676.12 KLO06411.1 - 0.0078 16.1 0.1 14 5.7 0.0 4.6 5 0 0 5 5 4 0 WD40-like Beta Propeller Repeat TIP49 PF06068.13 KLO06411.1 - 0.0079 15.4 0.0 4.2 6.5 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_24 PF13479.6 KLO06411.1 - 0.01 15.6 0.0 1.1 8.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KLO06411.1 - 0.011 16.2 0.1 1 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KLO06411.1 - 0.012 15.6 0.0 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 KLO06411.1 - 0.012 15.9 0.0 0.26 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KLO06411.1 - 0.013 14.7 0.8 1.1 8.4 0.2 2.9 3 0 0 3 3 3 0 KAP family P-loop domain AAA_30 PF13604.6 KLO06411.1 - 0.019 14.7 0.0 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Nup160 PF11715.8 KLO06411.1 - 0.038 12.6 0.2 20 3.6 0.0 3.2 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Torsin PF06309.11 KLO06411.1 - 0.044 13.9 0.0 16 5.6 0.0 2.8 2 0 0 2 2 2 0 Torsin AAA_14 PF13173.6 KLO06411.1 - 0.045 13.8 0.0 22 5.1 0.0 3.7 4 1 0 4 4 3 0 AAA domain ResIII PF04851.15 KLO06411.1 - 0.046 13.7 0.0 1.7 8.6 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KTI12 PF08433.10 KLO06411.1 - 0.063 12.7 0.0 2.5 7.5 0.0 2.5 3 0 0 3 3 2 0 Chromatin associated protein KTI12 CbiA PF01656.23 KLO06411.1 - 0.073 13.1 0.2 2.6 8.1 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Parvo_NS1 PF01057.17 KLO06411.1 - 0.085 11.9 0.0 4 6.4 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 KLO06411.1 - 0.088 12.8 0.0 10 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 KLO06411.1 - 0.09 11.7 0.0 2.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 KLO06411.1 - 0.13 11.9 0.0 0.7 9.5 0.0 2.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ADK PF00406.22 KLO06411.1 - 0.17 12.0 0.1 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Adenylate kinase Mg_chelatase PF01078.21 KLO06411.1 - 0.17 11.3 0.0 23 4.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI zf-C2H2 PF00096.26 KLO06412.1 - 8.7e-10 38.5 10.5 0.0011 19.3 0.5 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO06412.1 - 2.2e-08 34.2 10.1 0.013 16.2 0.4 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KLO06412.1 - 0.00098 19.4 1.0 1.6 9.2 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KLO06412.1 - 0.0014 19.0 16.8 0.013 15.9 0.7 4.2 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 KLO06412.1 - 0.0034 17.1 2.5 0.07 12.9 0.2 2.8 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KLO06412.1 - 0.004 16.9 0.4 0.004 16.9 0.4 4.2 5 0 0 5 5 5 1 C2H2-type zinc-finger domain IBR PF01485.21 KLO06412.1 - 0.012 15.8 4.9 0.095 12.9 0.8 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain WD40 PF00400.32 KLO06419.1 - 8.1e-52 172.1 30.8 5.1e-10 39.8 0.5 8.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO06419.1 - 8.6e-22 77.2 0.1 0.00027 21.2 0.0 7.6 2 1 6 8 8 7 6 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 KLO06419.1 - 2.6e-12 47.2 0.0 8.7e-06 26.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KLO06419.1 - 2.9e-12 47.3 0.0 6.5e-05 23.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KLO06419.1 - 3.9e-11 43.2 0.0 1.8e-05 24.7 0.0 2.9 2 1 0 2 2 2 2 NACHT domain NB-ARC PF00931.22 KLO06419.1 - 1.5e-10 40.7 0.0 7.7e-05 22.0 0.0 3.3 2 1 0 2 2 2 2 NB-ARC domain AAA PF00004.29 KLO06419.1 - 5e-09 36.7 0.0 0.0037 17.7 0.0 2.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Ge1_WD40 PF16529.5 KLO06419.1 - 1.6e-08 33.9 0.5 0.044 12.7 0.1 5.7 3 1 4 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RNA_helicase PF00910.22 KLO06419.1 - 1.4e-06 28.6 0.0 0.14 12.6 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_17 PF13207.6 KLO06419.1 - 1.8e-06 28.4 0.2 0.052 14.0 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KLO06419.1 - 6.2e-06 26.8 0.0 0.094 13.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain PD40 PF07676.12 KLO06419.1 - 1.6e-05 24.7 9.2 0.49 10.4 0.0 6.6 7 0 0 7 7 6 1 WD40-like Beta Propeller Repeat ADK PF00406.22 KLO06419.1 - 2.5e-05 24.4 0.2 0.028 14.5 0.0 3.4 3 1 0 3 3 3 1 Adenylate kinase AAA_24 PF13479.6 KLO06419.1 - 4.5e-05 23.3 0.0 0.038 13.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KLO06419.1 - 4.9e-05 23.9 0.0 0.32 11.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_33 PF13671.6 KLO06419.1 - 6.3e-05 23.2 0.0 0.27 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KLO06419.1 - 0.00015 21.1 0.0 0.0083 15.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.6 KLO06419.1 - 0.00016 21.7 0.0 0.58 10.2 0.0 3.4 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 KLO06419.1 - 0.00017 21.6 0.0 1.8 8.4 0.0 3.3 3 0 0 3 3 3 1 Rad17 P-loop domain eIF2A PF08662.11 KLO06419.1 - 0.00021 21.2 0.0 0.26 11.1 0.0 3.5 3 1 1 4 4 3 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KLO06419.1 - 0.00039 20.1 0.2 0.024 14.2 0.2 2.6 1 1 0 1 1 1 1 PQQ-like domain Ploopntkinase3 PF18751.1 KLO06419.1 - 0.0005 20.0 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 KLO06419.1 - 0.00062 19.4 0.1 8.9 5.8 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KLO06419.1 - 0.00083 19.6 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain PPV_E1_C PF00519.17 KLO06419.1 - 0.0019 17.1 0.0 0.96 8.2 0.0 2.2 2 0 0 2 2 2 2 Papillomavirus helicase MMR_HSR1 PF01926.23 KLO06419.1 - 0.0021 18.1 0.0 1.7 8.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Parvo_NS1 PF01057.17 KLO06419.1 - 0.0021 17.2 0.0 0.71 8.9 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 APS_kinase PF01583.20 KLO06419.1 - 0.0024 17.8 0.0 0.85 9.5 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase IstB_IS21 PF01695.17 KLO06419.1 - 0.0032 17.2 0.0 0.92 9.2 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein WD40_like PF17005.5 KLO06419.1 - 0.0045 16.4 0.0 0.66 9.3 0.0 3.0 2 1 0 3 3 3 1 WD40-like domain AAA_7 PF12775.7 KLO06419.1 - 0.0053 16.3 0.0 7.2 6.1 0.0 3.1 2 1 1 3 3 3 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KLO06419.1 - 0.0056 16.6 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_29 PF13555.6 KLO06419.1 - 0.007 16.1 0.0 1.8 8.4 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KLO06419.1 - 0.008 16.1 0.0 0.95 9.3 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase ATPase_2 PF01637.18 KLO06419.1 - 0.0085 16.0 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Nbas_N PF15492.6 KLO06419.1 - 0.0093 15.3 1.2 29 3.9 0.0 4.2 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Roc PF08477.13 KLO06419.1 - 0.011 15.9 0.0 20 5.4 0.0 4.0 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Nucleoporin_N PF08801.11 KLO06419.1 - 0.022 13.5 0.1 0.041 12.6 0.1 1.3 1 0 0 1 1 1 0 Nup133 N terminal like AAA_5 PF07728.14 KLO06419.1 - 0.026 14.5 0.0 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KLO06419.1 - 0.035 13.5 0.0 9.6 5.5 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KLO06419.1 - 0.064 12.5 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 KLO06419.1 - 0.073 12.8 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KLO06419.1 - 0.087 12.5 0.0 7.1 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KLO06419.1 - 0.17 11.0 0.0 9.1 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_PrkA PF08298.11 KLO06419.1 - 0.19 10.6 0.0 6.6 5.5 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain KAP_NTPase PF07693.14 KLO06419.1 - 0.3 10.3 4.3 8.5 5.5 0.0 2.9 2 1 1 3 3 3 0 KAP family P-loop domain Patatin PF01734.22 KLO06420.1 - 2.8e-13 50.5 0.1 6.6e-11 42.8 0.1 2.1 1 1 0 2 2 2 2 Patatin-like phospholipase TSC22 PF01166.18 KLO06426.1 - 0.14 12.5 3.4 0.084 13.2 0.7 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family MFS_1 PF07690.16 KLO06430.1 - 5.3e-38 130.8 25.5 1.4e-37 129.5 23.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO06430.1 - 3.6e-17 62.4 1.3 3.6e-17 62.4 1.3 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter DUF389 PF04087.14 KLO06430.1 - 0.017 15.1 0.1 0.18 11.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF389) Cytochrom_B561 PF03188.16 KLO06430.1 - 0.067 13.3 0.8 0.21 11.7 0.8 1.8 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 BAF250_C PF12031.8 KLO06432.1 - 0.1 11.9 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa TFIIA PF03153.13 KLO06434.1 - 1.7 8.6 5.3 10 6.0 5.2 2.2 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S6 PF01250.17 KLO06435.1 - 7.7e-22 77.4 0.0 1e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 SNase PF00565.17 KLO06436.1 - 3.5e-55 185.1 0.4 3.7e-19 69.2 0.0 6.6 5 2 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KLO06436.1 - 2e-20 73.0 0.0 4.7e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 KLO06436.1 - 0.0016 18.9 0.3 0.022 15.2 0.0 2.9 2 1 0 2 2 2 1 Agenet domain ABC1 PF03109.16 KLO06437.1 - 1e-32 112.8 0.0 1.9e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KLO06437.1 - 9.5e-05 22.1 0.1 0.00034 20.3 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 KLO06437.1 - 0.17 11.2 0.0 19 4.5 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain PC4 PF02229.16 KLO06438.1 - 8.8e-25 86.1 0.2 1.4e-24 85.4 0.2 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) RNA_pol_Rpc4 PF05132.14 KLO06438.1 - 0.24 11.8 6.4 0.31 11.5 6.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Stm1_N PF09598.10 KLO06438.1 - 0.86 10.5 14.8 0.29 12.0 12.1 1.5 2 0 0 2 2 2 0 Stm1 HECT PF00632.25 KLO06439.1 - 1.5e-94 316.9 0.0 2.5e-94 316.2 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 KLO06439.1 - 2.2e-91 306.6 0.1 2.2e-91 306.6 0.1 7.0 6 2 0 6 6 6 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KLO06439.1 - 1.4e-73 248.4 4.1 1.4e-73 248.4 4.1 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) UBM PF14377.6 KLO06439.1 - 1.4e-27 94.2 17.7 6.7e-11 41.2 0.6 4.5 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 KLO06439.1 - 1.7e-07 31.0 0.0 3.8e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain RNA_pol_A_bac PF01000.26 KLO06440.1 - 4.5e-26 91.4 0.0 8.9e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KLO06440.1 - 1.5e-18 66.0 0.0 1.9e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 KLO06440.1 - 0.072 12.9 0.0 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Fe_hyd_lg_C PF02906.14 KLO06441.1 - 7.9e-61 205.8 0.0 1.5e-60 204.9 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain CRIM PF16978.5 KLO06442.1 - 6.4e-23 81.5 0.0 9.9e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain KDZ PF18758.1 KLO06443.1 - 2e-84 282.7 0.1 3.5e-84 281.9 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Glyco_transf_7C PF02709.14 KLO06443.1 - 0.062 13.0 0.1 6.7 6.4 0.1 2.7 2 0 0 2 2 2 0 N-terminal domain of galactosyltransferase FIST_C PF10442.9 KLO06445.1 - 0.023 14.7 0.1 0.41 10.6 0.0 2.4 2 0 0 2 2 2 0 FIST C domain DUF4713 PF15831.5 KLO06446.1 - 7.1 7.2 8.1 0.51 10.8 3.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) F-box-like PF12937.7 KLO06448.1 - 1.2e-05 25.1 0.6 7.1e-05 22.6 0.3 2.5 2 0 0 2 2 2 1 F-box-like HEXIM PF15313.6 KLO06451.1 - 1 9.6 6.5 7.3 6.8 1.2 3.3 2 1 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein MIG-14_Wnt-bd PF06664.12 KLO06452.1 - 0.0088 15.3 0.4 0.013 14.8 0.4 1.2 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion CTV_P6 PF06706.11 KLO06452.1 - 0.014 15.1 1.7 0.04 13.6 1.7 1.7 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein Cadherin_C_2 PF16492.5 KLO06452.1 - 0.16 12.7 0.1 0.16 12.7 0.1 2.4 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF4577 PF15145.6 KLO06452.1 - 0.22 11.6 3.3 0.46 10.5 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) DUF3413 PF11893.8 KLO06452.1 - 0.8 8.8 5.3 1.6 7.8 5.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3413) MDFI PF15316.6 KLO06452.1 - 1.6 8.8 11.1 0.028 14.5 4.6 1.5 2 0 0 2 2 2 0 MyoD family inhibitor EphA2_TM PF14575.6 KLO06452.1 - 8.6 7.3 5.6 4.5 8.2 1.6 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain JmjC PF02373.22 KLO06454.1 - 0.015 15.7 0.0 0.95 9.9 0.0 2.6 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_4 PF08007.12 KLO06454.1 - 0.09 12.2 0.3 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Cupin superfamily protein TT_ORF2 PF02957.15 KLO06454.1 - 0.26 12.2 0.1 0.26 12.2 0.1 5.5 6 0 0 6 6 6 0 TT viral ORF2 RPA_C PF08784.11 KLO06457.1 - 0.00014 22.4 0.0 0.00025 21.7 0.0 1.4 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KLO06457.1 - 0.032 14.2 0.2 0.29 11.1 0.3 2.1 1 1 1 2 2 2 0 OB-fold nucleic acid binding domain DUF4843 PF16132.5 KLO06457.1 - 0.051 13.2 0.2 0.076 12.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4843) DNA_pol_A_exo1 PF01612.20 KLO06458.1 - 2.2e-11 43.8 0.0 8e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Spt5-NGN PF03439.13 KLO06458.1 - 7.8e-07 28.9 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF3912 PF13051.6 KLO06458.1 - 2.1e-05 24.7 0.0 0.0019 18.4 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) KOW PF00467.29 KLO06458.1 - 7.3e-05 22.6 15.4 0.00086 19.2 1.1 4.5 5 0 0 5 5 5 2 KOW motif DUF4265 PF14085.6 KLO06458.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Helicase_C PF00271.31 KLO06459.1 - 1.3e-15 57.7 0.0 1.2e-14 54.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO06459.1 - 4.1e-14 52.7 0.0 7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.14 KLO06459.1 - 0.012 14.4 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer ResIII PF04851.15 KLO06459.1 - 0.035 14.1 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KLO06459.1 - 0.095 11.4 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KLO06464.1 - 3.3e-05 24.0 0.1 4.4e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 Transposase F-box PF00646.33 KLO06466.1 - 1.5e-05 24.7 0.1 5.5e-05 22.9 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO06466.1 - 0.013 15.4 0.0 0.042 13.7 0.0 1.9 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 KLO06466.1 - 0.016 15.1 0.2 0.046 13.6 0.0 1.9 2 0 0 2 2 2 0 F-box POTRA_TamA_1 PF17243.2 KLO06466.1 - 0.021 14.9 0.4 0.12 12.5 0.1 2.4 2 0 0 2 2 2 0 POTRA domain TamA domain 1 DUF5037 PF16440.5 KLO06466.1 - 0.066 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5037) Lebercilin PF15619.6 KLO06466.1 - 1.8 8.2 8.7 0.046 13.4 2.1 1.7 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fungal_trans PF04082.18 KLO06469.1 - 2.9e-09 36.3 0.4 2.9e-09 36.3 0.4 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO06469.1 - 0.0024 18.0 9.6 0.004 17.2 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arm-DNA-bind_5 PF17293.2 KLO06469.1 - 0.22 12.0 1.6 1.7 9.1 0.2 2.6 2 0 0 2 2 2 0 Arm DNA-binding domain Seryl_tRNA_N PF02403.22 KLO06469.1 - 0.31 11.3 3.1 0.29 11.4 0.9 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain F-box PF00646.33 KLO06471.1 - 0.007 16.2 0.1 0.029 14.2 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KLO06471.1 - 0.027 14.3 0.0 0.085 12.8 0.0 1.9 1 0 0 1 1 1 0 F-box-like OS-D PF03392.13 KLO06471.1 - 0.099 12.7 0.2 0.5 10.5 0.2 2.2 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D Speriolin_C PF15059.6 KLO06471.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Speriolin C-terminus F-box-like PF12937.7 KLO06472.1 - 0.049 13.5 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KLO06472.1 - 0.093 12.6 0.0 0.36 10.8 0.0 2.1 1 0 0 1 1 1 0 F-box domain POTRA_TamA_1 PF17243.2 KLO06477.1 - 0.05 13.7 0.1 0.33 11.1 0.0 2.2 1 1 1 2 2 2 0 POTRA domain TamA domain 1 F-box PF00646.33 KLO06478.1 - 0.00035 20.4 0.1 0.00071 19.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain Ig_5 PF16681.5 KLO06478.1 - 0.0067 16.8 0.1 0.012 16.0 0.1 1.4 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain F-box-like PF12937.7 KLO06478.1 - 0.063 13.2 0.5 0.097 12.6 0.0 1.6 2 0 0 2 2 2 0 F-box-like Fcf1 PF04900.12 KLO06479.1 - 1.3e-32 112.1 0.1 2.2e-32 111.4 0.1 1.4 1 0 0 1 1 1 1 Fcf1 LRIF1 PF15741.5 KLO06479.1 - 0.014 14.0 0.5 0.014 14.0 0.5 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Lipase_3 PF01764.25 KLO06480.1 - 6.4e-15 55.3 0.0 8.4e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KLO06480.1 - 0.016 14.8 0.0 0.041 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 KLO06482.1 - 4.3e-15 55.8 0.0 5.8e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KLO06482.1 - 0.00067 20.3 0.0 0.00078 20.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KLO06482.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Atg14 PF10186.9 KLO06484.1 - 0.14 11.2 1.1 0.22 10.6 1.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-RVT PF13966.6 KLO06487.1 - 0.0023 18.6 0.1 0.0056 17.4 0.1 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 KLO06487.1 - 0.0089 16.2 0.1 0.019 15.1 0.1 1.6 1 0 0 1 1 1 1 RNase H zf_UBZ PF18439.1 KLO06489.1 - 1.6 8.4 3.9 2.2 7.9 0.7 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Kdo PF06293.14 KLO06490.1 - 1.8e-05 24.2 0.0 3.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO06490.1 - 0.00042 20.3 1.6 0.00068 19.6 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KLO06490.1 - 0.031 13.8 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KLO06490.1 - 0.032 13.6 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain zf-MYND PF01753.18 KLO06491.1 - 2.5e-07 30.6 5.8 2.5e-07 30.6 5.8 1.9 2 0 0 2 2 2 1 MYND finger Nup54 PF13874.6 KLO06491.1 - 0.02 15.0 0.1 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 PspA_IM30 PF04012.12 KLO06491.1 - 0.053 13.1 1.4 0.061 12.9 0.1 1.7 2 0 0 2 2 2 0 PspA/IM30 family zf-RING_UBOX PF13445.6 KLO06495.1 - 9.4e-05 22.4 8.5 0.00022 21.2 8.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KLO06495.1 - 9.7e-05 22.4 6.7 0.00077 19.6 6.7 2.3 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KLO06495.1 - 0.00073 19.4 10.4 0.0039 17.0 10.4 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KLO06495.1 - 0.007 16.2 4.1 0.013 15.3 4.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 KLO06495.1 - 1.6 8.7 13.2 0.44 10.4 9.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO06495.1 - 2.4 8.6 15.1 11 6.4 15.1 2.2 1 1 0 1 1 1 0 Ring finger domain BUD22 PF09073.10 KLO06495.1 - 4.7 6.4 16.4 0.35 10.2 10.7 1.9 2 0 0 2 2 2 0 BUD22 zf-RING_10 PF16685.5 KLO06495.1 - 9.9 6.4 12.6 3.9 7.7 5.9 2.5 1 1 1 2 2 2 0 zinc RING finger of MSL2 PHD PF00628.29 KLO06496.1 - 0.24 11.3 12.5 0.17 11.8 7.3 2.3 2 0 0 2 2 2 0 PHD-finger zf-RING_UBOX PF13445.6 KLO06497.1 - 3.7e-09 36.5 4.2 4.3e-09 36.3 2.7 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KLO06497.1 - 1.9e-05 24.4 4.0 4.3e-05 23.3 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO06497.1 - 5.8e-05 22.9 3.0 5.8e-05 22.9 3.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KLO06497.1 - 0.00043 20.4 4.3 0.00043 20.4 4.3 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KLO06497.1 - 0.00085 19.6 8.5 0.0055 17.0 8.8 2.3 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KLO06497.1 - 0.0044 16.9 4.9 0.014 15.4 4.9 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 KLO06497.1 - 0.072 12.9 0.5 0.19 11.6 0.3 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PHD_4 PF16866.5 KLO06497.1 - 0.26 11.4 1.8 2.2 8.5 1.8 2.2 1 1 0 1 1 1 0 PHD-finger zf-RING_10 PF16685.5 KLO06497.1 - 0.42 10.8 3.4 0.94 9.7 3.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 KLO06497.1 - 0.9 9.5 10.2 11 5.9 10.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Etmic-2 PF06670.11 KLO06499.1 - 0.1 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 DUF3511 PF12023.8 KLO06500.1 - 0.065 13.1 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) SUR7 PF06687.12 KLO06500.1 - 1.4 8.5 16.3 3.4 7.2 8.9 2.6 1 1 1 2 2 2 0 SUR7/PalI family Pkinase PF00069.25 KLO06501.1 - 2.3e-24 86.2 0.0 2.9e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO06501.1 - 6.2e-14 51.9 0.0 7.8e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO06501.1 - 8.9e-08 31.3 0.0 9e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO06501.1 - 0.0085 16.0 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Wzy_C PF04932.15 KLO06502.1 - 0.19 11.3 4.6 0.23 11.1 4.6 1.2 1 0 0 1 1 1 0 O-Antigen ligase Herpes_UL49_5 PF05702.11 KLO06503.1 - 0.16 12.1 0.2 0.51 10.5 0.0 1.7 1 1 1 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein F-box-like PF12937.7 KLO06505.1 - 1.8e-08 34.1 1.2 1.5e-07 31.2 0.5 2.6 2 0 0 2 2 2 1 F-box-like Oxidored_q3 PF00499.20 KLO06506.1 - 0.083 12.6 11.9 0.91 9.2 6.8 2.7 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Transp_cyt_pur PF02133.15 KLO06507.1 - 1.7e-23 83.1 29.3 2.7e-23 82.5 29.3 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DEAD PF00270.29 KLO06511.1 - 3.7e-48 163.6 0.0 7.2e-48 162.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO06511.1 - 4.3e-22 78.6 0.1 2.9e-21 75.9 0.0 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KLO06511.1 - 2.1e-18 66.3 0.2 4.3e-18 65.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KLO06511.1 - 0.00012 22.1 0.0 0.00034 20.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NAPRTase_N PF17767.1 KLO06511.1 - 0.091 13.1 0.2 1.8 8.9 0.1 2.4 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain p450 PF00067.22 KLO06513.1 - 8.2e-69 232.5 0.0 9.4e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO06514.1 - 1.8e-70 238.0 0.0 2.2e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KLO06515.1 - 2.4e-62 210.7 0.0 4.6e-62 209.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO06515.1 - 1.4e-43 149.1 0.0 2.5e-43 148.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 KLO06515.1 - 2.5e-37 128.6 0.0 7e-37 127.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) APH PF01636.23 KLO06515.1 - 0.014 15.3 0.0 0.096 12.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO06515.1 - 0.17 10.6 0.0 0.48 9.1 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Cation_efflux PF01545.21 KLO06516.1 - 0.00028 20.7 4.8 0.00055 19.7 4.8 1.6 1 1 0 1 1 1 1 Cation efflux family Aminotran_1_2 PF00155.21 KLO06517.1 - 2e-40 139.1 0.0 2.6e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KLO06517.1 - 0.12 10.9 0.0 0.25 9.8 0.0 1.5 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RNA_Me_trans PF04252.13 KLO06518.1 - 2.1e-73 246.2 0.0 3e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Chitin_synth_2 PF03142.15 KLO06519.1 - 3.9e-242 804.6 0.5 5.7e-242 804.0 0.5 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KLO06519.1 - 9.9e-137 457.0 0.0 2.8e-136 455.5 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KLO06519.1 - 6e-18 64.5 0.1 2.5e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KLO06519.1 - 8.1e-16 57.9 0.0 3.7e-11 43.0 0.0 3.0 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KLO06519.1 - 3.6e-11 43.4 4.9 3.6e-11 43.4 4.9 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KLO06519.1 - 6.1e-10 39.4 0.0 5.8e-09 36.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KLO06519.1 - 0.00014 21.7 0.0 0.12 12.2 0.0 2.8 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KLO06519.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 CLN3 PF02487.17 KLO06520.1 - 7.1e-129 430.3 0.3 8.3e-129 430.1 0.3 1.0 1 0 0 1 1 1 1 CLN3 protein Abhydrolase_3 PF07859.13 KLO06521.1 - 6.4e-47 160.1 0.0 8.5e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KLO06521.1 - 0.003 16.5 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 KLO06521.1 - 0.0075 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KLO06521.1 - 0.094 12.2 0.0 4.9 6.6 0.0 2.3 3 0 0 3 3 3 0 Prolyl oligopeptidase family BTB PF00651.31 KLO06523.1 - 6.1e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-MYND PF01753.18 KLO06524.1 - 6.2e-09 35.8 15.7 6.2e-09 35.8 15.7 2.1 2 0 0 2 2 2 1 MYND finger Rhodanese_C PF12368.8 KLO06524.1 - 0.038 14.4 6.0 0.11 12.8 6.0 1.8 1 0 0 1 1 1 0 Rhodanase C-terminal zf-C6H2 PF15801.5 KLO06524.1 - 4.2 7.8 14.5 15 6.0 10.7 3.2 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding SRF-TF PF00319.18 KLO06525.1 - 2.6e-18 65.2 0.0 3.7e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DnaJ_CXXCXGXG PF00684.19 KLO06526.1 - 0.0028 18.0 2.4 0.62 10.5 0.1 2.4 2 0 0 2 2 2 2 DnaJ central domain DUF5351 PF17302.2 KLO06526.1 - 0.031 14.4 0.2 0.066 13.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5351) Peptidase_M56 PF05569.11 KLO06527.1 - 0.017 14.3 0.1 0.023 13.9 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Phage_holin_3_6 PF07332.11 KLO06527.1 - 0.035 14.1 1.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III CD34_antigen PF06365.12 KLO06527.1 - 0.051 13.2 0.1 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM154 PF15102.6 KLO06527.1 - 0.051 13.5 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family BTB PF00651.31 KLO06529.1 - 5e-07 29.9 0.0 9.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO06530.1 - 5.6e-07 29.8 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 KLO06530.1 - 0.061 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DnaJ PF00226.31 KLO06531.1 - 7.8e-09 35.5 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain BTB PF00651.31 KLO06532.1 - 8e-09 35.7 0.1 1.4e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Orthopox_F14 PF06076.12 KLO06532.1 - 0.11 12.8 0.3 0.73 10.2 0.1 2.6 3 0 0 3 3 3 0 Orthopoxvirus F14 protein BTB PF00651.31 KLO06533.1 - 1.6e-06 28.3 0.0 2.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO06534.1 - 6.2e-08 32.9 0.0 1.2e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain S-methyl_trans PF02574.16 KLO06534.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Homocysteine S-methyltransferase Macoilin PF09726.9 KLO06541.1 - 2.5 6.6 4.5 3.4 6.1 4.5 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_16 PF00722.21 KLO06544.1 - 1.5e-20 73.4 0.0 2.3e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 F-box-like PF12937.7 KLO06547.1 - 5.6e-05 22.9 0.1 0.00014 21.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like Sda PF08970.10 KLO06547.1 - 0.11 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Sporulation inhibitor A F-box-like PF12937.7 KLO06548.1 - 0.021 14.7 0.0 0.059 13.3 0.0 1.8 1 0 0 1 1 1 0 F-box-like SRF-TF PF00319.18 KLO06550.1 - 1.7e-22 78.6 0.0 2.2e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) BTB PF00651.31 KLO06554.1 - 2.6e-08 34.1 0.0 4.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO06555.1 - 4.3e-09 36.6 0.0 1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BCS1_N PF08740.11 KLO06556.1 - 6.6e-44 150.1 3.2 6.6e-44 150.1 3.2 3.3 3 1 0 3 3 2 1 BCS1 N terminal AAA PF00004.29 KLO06556.1 - 8.9e-15 55.3 0.0 1.4e-06 28.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KLO06556.1 - 0.0018 17.5 0.0 0.0038 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KLO06556.1 - 0.0031 17.9 0.1 0.0031 17.9 0.1 3.0 3 2 0 3 3 2 1 AAA ATPase domain CAF-1_p150 PF11600.8 KLO06556.1 - 0.0053 16.5 48.4 0.0053 16.5 48.4 1.7 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_29 PF13555.6 KLO06556.1 - 0.0056 16.4 0.0 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KLO06556.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KLO06556.1 - 0.28 11.7 0.1 0.28 11.7 0.1 2.5 2 1 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KLO06556.1 - 0.31 11.2 0.0 0.31 11.2 0.0 2.5 2 0 0 2 2 1 0 AAA domain XRN_M PF17846.1 KLO06556.1 - 0.55 9.1 17.6 1.2 8.0 17.6 1.5 1 0 0 1 1 1 0 Xrn1 helical domain AAA_11 PF13086.6 KLO06556.1 - 0.77 9.5 16.8 26 4.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain MAP7 PF05672.11 KLO06556.1 - 2.4 7.8 50.2 0.32 10.7 44.3 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family BTB PF00651.31 KLO06557.1 - 1.3e-07 31.8 0.0 3.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 KLO06557.1 - 0.0086 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 KLO06558.1 - 3.2e-07 30.5 0.1 5.8e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 KLO06558.1 - 0.14 12.4 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain HTH_38 PF13936.6 KLO06559.1 - 3.2e-05 23.6 0.0 0.00015 21.5 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KLO06559.1 - 0.00041 20.0 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KLO06559.1 - 0.0051 17.4 2.2 0.26 12.0 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain GerE PF00196.19 KLO06559.1 - 0.0074 15.8 0.1 0.019 14.5 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_Tnp_ISL3 PF13542.6 KLO06559.1 - 0.058 12.8 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 NRBF2_MIT PF17169.4 KLO06559.1 - 0.063 13.5 0.1 0.57 10.4 0.0 2.1 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 HTH_28 PF13518.6 KLO06559.1 - 0.082 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain SpoIIID PF12116.8 KLO06559.1 - 0.094 12.8 0.1 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 Stage III sporulation protein D HTH_5 PF01022.20 KLO06559.1 - 0.15 12.0 0.6 0.27 11.1 0.6 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_50 PF18024.1 KLO06559.1 - 0.16 11.6 0.2 0.29 10.8 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Aldo_ket_red PF00248.21 KLO06560.1 - 7e-68 229.0 0.0 8e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KLO06561.1 - 9.6e-60 202.3 0.0 1.1e-59 202.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BTB PF00651.31 KLO06564.1 - 0.00044 20.4 0.3 0.0071 16.6 0.3 2.5 1 1 0 1 1 1 1 BTB/POZ domain DBD_Tnp_Mut PF03108.15 KLO06566.1 - 3.1 7.9 9.2 8 6.5 0.2 2.4 2 0 0 2 2 2 0 MuDR family transposase PUL PF08324.11 KLO06568.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 PUL domain RHH_1 PF01402.21 KLO06568.1 - 0.17 11.9 1.6 0.38 10.8 0.8 2.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family PUL PF08324.11 KLO06570.1 - 0.11 11.8 0.2 0.35 10.1 0.0 1.8 2 0 0 2 2 2 0 PUL domain MutS_III PF05192.18 KLO06570.1 - 0.12 12.5 0.7 0.17 12.1 0.7 1.4 1 1 0 1 1 1 0 MutS domain III Glyco_hydro_16 PF00722.21 KLO06572.1 - 6.1e-20 71.4 0.0 9.8e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Phage_holin_3_6 PF07332.11 KLO06572.1 - 0.39 10.8 2.3 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III 4HBT PF03061.22 KLO06574.1 - 8.1e-10 38.9 0.0 1.3e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT PF03061.22 KLO06575.1 - 1.4e-07 31.8 0.1 2.8e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KLO06575.1 - 0.00045 20.5 0.0 0.00047 20.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily ubiquitin PF00240.23 KLO06576.1 - 3.4e-25 87.6 0.2 3.8e-25 87.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KLO06576.1 - 1.7e-13 50.2 0.1 1.8e-13 50.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KLO06576.1 - 8.9e-06 25.5 0.0 9.8e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain UN_NPL4 PF11543.8 KLO06576.1 - 0.00029 21.3 0.0 0.00041 20.8 0.0 1.3 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.6 KLO06576.1 - 0.0016 18.9 0.1 0.0016 18.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KLO06576.1 - 0.074 13.2 0.1 0.2 11.7 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KLO06576.1 - 0.12 13.0 0.0 0.14 12.7 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ThiS PF02597.20 KLO06576.1 - 0.14 12.8 0.2 0.27 11.9 0.2 1.4 1 1 0 1 1 1 0 ThiS family F-box-like PF12937.7 KLO06577.1 - 1e-05 25.3 0.0 2.6e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 F-box-like Methyltransf_25 PF13649.6 KLO06578.1 - 1.5e-13 51.3 0.0 3.6e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO06578.1 - 2.8e-12 46.8 0.0 3.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO06578.1 - 4.4e-09 36.3 0.0 8.1e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO06578.1 - 5e-09 36.7 0.0 8.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO06578.1 - 5.6e-06 25.9 0.0 3.6e-05 23.2 0.0 2.0 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KLO06578.1 - 4.7e-05 24.1 0.0 9.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KLO06578.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FtsJ PF01728.19 KLO06578.1 - 0.22 11.6 0.0 0.39 10.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Spc7 PF08317.11 KLO06579.1 - 0.38 9.6 29.2 0.029 13.2 2.6 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Phage_int_SAM_1 PF02899.17 KLO06579.1 - 0.48 10.7 4.9 8.4 6.8 0.3 3.5 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF2353 PF09789.9 KLO06579.1 - 0.49 9.7 23.9 2.9 7.2 5.2 3.1 2 1 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) ATF7IP_BD PF16788.5 KLO06579.1 - 0.84 9.7 8.5 0.061 13.4 1.5 2.5 2 1 0 2 2 2 0 ATF-interacting protein binding domain DUF812 PF05667.11 KLO06579.1 - 1.1 8.1 18.4 1.8 7.3 18.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Rootletin PF15035.6 KLO06579.1 - 1.2 9.2 25.5 1.6 8.7 18.5 2.3 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion PriC PF07445.12 KLO06579.1 - 1.7 8.6 18.4 0.18 11.7 11.1 2.4 2 0 0 2 2 2 0 Primosomal replication protein priC Methyltransf_25 PF13649.6 KLO06580.1 - 7.6e-14 52.2 0.0 2.4e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO06580.1 - 4e-11 43.0 0.0 6.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO06580.1 - 8e-11 42.4 0.0 1.5e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO06580.1 - 6.5e-09 35.8 0.0 1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO06580.1 - 6.6e-07 28.9 0.0 1.3e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KLO06580.1 - 1.1e-05 26.1 0.0 1.9e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO06581.1 - 3.7e-13 49.6 0.0 4.8e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO06581.1 - 5.1e-12 46.3 0.0 1.8e-11 44.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO06581.1 - 1.9e-11 44.5 0.0 3.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO06581.1 - 6.5e-09 35.8 0.0 1.9e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO06581.1 - 3.7e-08 34.0 0.0 1.5e-07 32.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO06581.1 - 6.2e-08 32.3 0.0 5.2e-07 29.2 0.0 2.3 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KLO06581.1 - 0.01 15.7 0.0 0.027 14.3 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 KLO06581.1 - 0.08 12.2 0.0 0.21 10.9 0.0 1.9 2 1 0 2 2 2 0 O-methyltransferase domain Methyltransf_25 PF13649.6 KLO06582.1 - 7.8e-12 45.7 0.0 1.6e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO06582.1 - 1.7e-11 44.2 0.0 2.4e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO06582.1 - 2.5e-09 36.8 0.0 1.8e-08 34.0 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KLO06582.1 - 3.5e-09 37.2 0.0 5.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO06582.1 - 4.8e-09 36.2 0.0 1.9e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO06582.1 - 1.8e-05 25.4 0.0 4.7e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KLO06582.1 - 0.13 11.6 0.0 2.5 7.4 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain TPMT PF05724.11 KLO06582.1 - 0.15 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) 14-3-3 PF00244.20 KLO06583.1 - 1e-107 358.7 5.7 1.2e-107 358.5 5.7 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 KLO06583.1 - 0.00011 22.4 2.0 0.46 10.8 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Imm71 PF15602.6 KLO06583.1 - 0.005 16.9 0.0 0.074 13.1 0.0 2.1 1 1 1 2 2 2 1 Immunity protein 71 RasGAP PF00616.19 KLO06584.1 - 6.3e-21 75.0 0.1 2.6e-14 53.4 0.0 2.5 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KLO06584.1 - 0.00099 19.3 1.0 0.0031 17.7 0.3 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 KLO06584.1 - 0.0068 16.3 0.7 0.076 12.9 0.1 2.9 3 0 0 3 3 3 1 Cell morphogenesis C-terminal Pep1_7 PF17232.2 KLO06584.1 - 0.028 14.9 0.1 15 6.2 0.0 3.0 2 0 0 2 2 2 0 Elicitor peptide 1-7 MFS_5 PF05631.14 KLO06584.1 - 0.18 10.7 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM Methyltransf_25 PF13649.6 KLO06586.1 - 2.3e-12 47.5 0.0 5.9e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO06586.1 - 1.6e-11 44.4 0.0 2.3e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO06586.1 - 5.3e-11 42.5 0.0 1.2e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO06586.1 - 3.2e-10 40.5 0.0 6.7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO06586.1 - 8e-08 31.9 0.0 3.8e-07 29.7 0.0 2.0 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KLO06586.1 - 2.4e-06 28.2 0.0 5.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO06586.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 KLO06586.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase PrmA PF06325.13 KLO06586.1 - 0.059 12.8 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KLO06587.1 - 3.8e-09 37.1 0.0 1.3e-08 35.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO06587.1 - 3.2e-08 33.6 0.0 4.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO06587.1 - 1.2e-06 29.1 0.0 4e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO06587.1 - 6e-06 26.1 0.0 6.3e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO06587.1 - 0.0017 19.1 0.0 0.0046 17.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KLO06587.1 - 0.039 13.6 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CheR PF01739.18 KLO06587.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_29 PF03141.16 KLO06587.1 - 0.23 10.0 0.0 0.62 8.5 0.0 1.6 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Acetyltransf_3 PF13302.7 KLO06588.1 - 2.6e-10 41.1 0.0 3.6e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain p450 PF00067.22 KLO06589.1 - 1e-70 238.8 0.0 1.3e-70 238.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Gate PF07670.14 KLO06591.1 - 4.7 7.5 10.6 0.11 12.7 2.4 2.5 2 2 0 2 2 2 0 Nucleoside recognition Flg_new PF09479.10 KLO06593.1 - 0.088 13.0 0.0 0.097 12.9 0.0 1.2 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) CCDC106 PF15794.5 KLO06594.1 - 0.0086 15.8 1.4 0.012 15.4 1.4 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 MFS_1 PF07690.16 KLO06595.1 - 1.2e-25 90.2 30.5 1.2e-25 90.2 30.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily BRI3BP PF14965.6 KLO06595.1 - 8.6 5.8 8.3 1.9 8.0 0.8 2.7 2 1 0 2 2 2 0 Negative regulator of p53/TP53 p450 PF00067.22 KLO06596.1 - 8.7e-47 159.9 0.0 8.3e-42 143.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 TEA PF01285.18 KLO06600.1 - 1.3e-14 53.9 0.1 2.3e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 TEA/ATTS domain UEV PF05743.13 KLO06601.1 - 7.5e-34 116.2 0.0 1.2e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KLO06601.1 - 4.5e-28 97.0 0.4 7.8e-28 96.2 0.4 1.4 1 0 0 1 1 1 1 Vps23 core domain MSC PF09402.10 KLO06604.1 - 1.6e-89 300.7 0.0 2.3e-89 300.2 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KLO06604.1 - 8.8e-09 34.9 0.0 5e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 HeH/LEM domain Pkinase_fungal PF17667.1 KLO06605.1 - 5.5e-56 190.1 0.0 2.9e-55 187.7 0.0 1.9 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO06605.1 - 6.5e-05 22.4 1.2 0.00014 21.3 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KLO06605.1 - 0.2 11.0 2.4 0.25 10.7 0.7 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cu_bind_like PF02298.17 KLO06606.1 - 6.8e-05 22.8 0.3 0.00016 21.6 0.3 1.6 1 0 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 KLO06606.1 - 0.0049 17.3 0.2 0.011 16.2 0.2 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Mso1_Sec1_bdg PF14475.6 KLO06607.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Sec1-binding region of Mso1 Pyr_redox_2 PF07992.14 KLO06608.1 - 8.9e-13 48.1 0.0 1.7e-07 30.8 0.0 2.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO06608.1 - 0.022 14.3 0.5 5 6.6 0.3 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KLO06608.1 - 0.045 13.7 0.0 7.1 6.6 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding HTH_29 PF13551.6 KLO06613.1 - 4.1e-05 23.5 0.1 0.00012 22.1 0.1 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KLO06613.1 - 0.0001 22.0 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 KLO06613.1 - 0.00018 21.2 0.1 0.0029 17.3 0.4 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain GerE PF00196.19 KLO06613.1 - 0.0009 18.7 0.0 0.0024 17.4 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_7 PF02796.15 KLO06613.1 - 0.0055 16.8 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_50 PF18024.1 KLO06613.1 - 0.032 13.8 0.6 0.043 13.4 0.6 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain ABC_membrane PF00664.23 KLO06617.1 - 1.2e-82 277.6 21.0 5.3e-44 150.9 8.1 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KLO06617.1 - 1.5e-60 203.6 0.0 3.8e-29 101.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KLO06617.1 - 1.3e-17 64.0 0.4 9.9e-07 28.4 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KLO06617.1 - 2e-12 47.6 0.0 0.0049 16.7 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KLO06617.1 - 6.9e-10 39.6 1.7 0.00025 21.4 0.1 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KLO06617.1 - 7.1e-08 32.8 1.1 0.077 13.3 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KLO06617.1 - 1.9e-07 30.7 0.1 0.018 14.8 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KLO06617.1 - 8e-07 29.0 0.1 1.8 8.3 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_18 PF13238.6 KLO06617.1 - 3.3e-06 27.7 0.0 0.013 16.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KLO06617.1 - 4.2e-06 26.5 1.3 0.28 10.7 0.0 4.2 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 KLO06617.1 - 1e-05 24.9 0.0 0.13 11.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.6 KLO06617.1 - 1.4e-05 25.4 0.9 0.71 10.1 0.3 3.7 2 1 1 3 3 3 2 AAA domain SbcCD_C PF13558.6 KLO06617.1 - 3.4e-05 24.0 2.3 0.26 11.6 0.0 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 KLO06617.1 - 4.6e-05 22.4 0.8 0.2 10.4 0.0 2.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class Sigma54_activ_2 PF14532.6 KLO06617.1 - 8.3e-05 22.7 0.1 1.5 9.0 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_30 PF13604.6 KLO06617.1 - 0.00013 21.8 5.2 0.035 13.8 0.1 3.9 3 2 0 3 3 2 2 AAA domain AAA_33 PF13671.6 KLO06617.1 - 0.00045 20.4 0.1 2 8.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KLO06617.1 - 0.00052 19.8 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KLO06617.1 - 0.00065 19.6 0.0 0.59 10.0 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 KLO06617.1 - 0.00066 19.8 1.8 0.098 12.7 0.0 2.9 2 1 1 3 3 2 1 Helicase HerA, central domain AAA_5 PF07728.14 KLO06617.1 - 0.00085 19.3 0.0 1.9 8.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 KLO06617.1 - 0.00093 18.4 0.0 0.16 11.1 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit APS_kinase PF01583.20 KLO06617.1 - 0.00095 19.1 0.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_24 PF13479.6 KLO06617.1 - 0.0019 18.0 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KLO06617.1 - 0.002 18.6 0.0 0.59 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KLO06617.1 - 0.0047 16.3 0.0 2.5 7.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family TniB PF05621.11 KLO06617.1 - 0.005 16.3 0.0 7.3 6.0 0.0 3.5 4 0 0 4 4 4 0 Bacterial TniB protein Mg_chelatase PF01078.21 KLO06617.1 - 0.012 15.0 0.0 5.8 6.2 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KLO06617.1 - 0.018 15.5 1.7 8.1 6.9 0.3 3.3 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KLO06617.1 - 0.02 14.8 0.1 7.7 6.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain CoaE PF01121.20 KLO06617.1 - 0.024 14.3 0.2 7.5 6.2 0.0 2.7 2 0 0 2 2 2 0 Dephospho-CoA kinase CobA_CobO_BtuR PF02572.15 KLO06617.1 - 0.026 14.8 1.0 1.7 8.9 0.0 2.8 3 0 0 3 3 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP PRK PF00485.18 KLO06617.1 - 0.027 14.2 0.1 5.1 6.8 0.1 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Sigma54_activat PF00158.26 KLO06617.1 - 0.03 14.0 0.0 6 6.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain CbiA PF01656.23 KLO06617.1 - 0.04 14.0 0.5 3.4 7.7 0.0 2.9 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 KLO06617.1 - 0.041 14.3 0.0 17 5.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATPase PF06745.13 KLO06617.1 - 0.053 12.9 0.2 7.4 5.8 0.0 2.8 3 0 0 3 3 2 0 KaiC Cytidylate_kin PF02224.18 KLO06617.1 - 0.056 13.2 0.2 9.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase DUF3987 PF13148.6 KLO06617.1 - 0.066 12.2 1.6 7.2 5.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) CobU PF02283.16 KLO06617.1 - 0.099 12.2 0.1 2.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_7 PF12775.7 KLO06617.1 - 0.11 12.0 0.1 9.3 5.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 KLO06617.1 - 0.14 11.6 0.5 19 4.6 0.0 3.3 3 0 0 3 3 3 0 PhoH-like protein NB-ARC PF00931.22 KLO06617.1 - 0.14 11.3 0.1 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 KLO06617.1 - 0.22 10.7 0.1 24 4.0 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Transcrip_act PF04949.13 KLO06618.1 - 0.0018 18.2 1.9 0.0028 17.6 1.9 1.2 1 0 0 1 1 1 1 Transcriptional activator Molybdopterin PF00384.22 KLO06619.1 - 1.1e-70 238.8 0.0 4.8e-70 236.7 0.0 1.8 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KLO06619.1 - 1.6e-19 69.7 0.1 4.8e-19 68.2 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KLO06619.1 - 2.7e-17 62.0 0.2 2.7e-17 62.0 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KLO06619.1 - 7.8e-17 61.7 0.1 2.4e-16 60.1 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KLO06619.1 - 5.7e-09 35.8 0.4 5.7e-09 35.8 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KLO06619.1 - 0.031 14.0 0.1 0.67 9.7 0.1 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain PNP_UDP_1 PF01048.20 KLO06620.1 - 5.7e-38 130.5 0.1 1e-37 129.7 0.1 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily 60KD_IMP PF02096.20 KLO06621.1 - 0.0088 16.0 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein RIFIN PF02009.16 KLO06621.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Rifin CbtB PF09489.10 KLO06621.1 - 0.12 12.5 0.9 0.12 12.5 0.9 2.3 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) AA_permease_2 PF13520.6 KLO06622.1 - 5.5e-39 134.2 39.0 6.8e-39 133.9 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF5527 PF17665.1 KLO06623.1 - 1.4 8.5 2.6 0.74 9.3 0.6 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5527) SUR7 PF06687.12 KLO06624.1 - 6.8e-13 48.7 14.5 2.4e-12 47.0 14.5 1.7 1 1 0 1 1 1 1 SUR7/PalI family DUF1230 PF06799.11 KLO06624.1 - 0.064 13.4 0.6 0.13 12.4 0.1 1.7 1 1 1 2 2 2 0 Conserved in the green lineage and diatoms 27 DUF1084 PF06454.11 KLO06624.1 - 0.64 9.3 5.7 0.27 10.6 1.4 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1084) Ribosomal_L27e PF01777.18 KLO06625.1 - 4.1e-33 113.6 6.2 5.4e-33 113.2 6.2 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KLO06625.1 - 3.9e-05 23.4 0.9 9.2e-05 22.3 0.9 1.6 1 0 0 1 1 1 1 KOW motif DEAD PF00270.29 KLO06626.1 - 9e-17 61.4 0.0 1.9e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO06626.1 - 0.0009 19.6 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PrgH PF09480.10 KLO06626.1 - 0.012 15.0 0.0 3.6 6.8 0.0 2.1 1 1 1 2 2 2 0 Type III secretion system protein PrgH-EprH (PrgH) ResIII PF04851.15 KLO06626.1 - 0.032 14.2 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KLO06626.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain zf-C2H2 PF00096.26 KLO06627.1 - 6.4e-07 29.5 12.8 0.0099 16.3 0.8 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO06627.1 - 0.00031 21.3 13.6 0.31 12.0 1.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger C1_4 PF07975.12 KLO06627.1 - 0.027 14.7 2.6 0.055 13.7 0.1 2.5 3 0 0 3 3 3 0 TFIIH C1-like domain IBR PF01485.21 KLO06627.1 - 0.062 13.5 11.6 0.17 12.1 2.9 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FOXP-CC PF16159.5 KLO06627.1 - 0.35 11.5 3.2 0.97 10.1 0.4 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain MFS_1 PF07690.16 KLO06628.1 - 7e-27 94.3 31.6 8.4e-22 77.6 8.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KLO06630.1 - 1.3e-23 83.5 31.2 2.8e-17 62.7 7.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO06630.1 - 1.7e-05 23.9 16.4 2.4e-05 23.4 16.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KLO06630.1 - 0.00013 21.0 9.6 0.021 13.7 1.2 2.4 2 0 0 2 2 2 2 MFS_1 like family zf-C2H2_4 PF13894.6 KLO06632.1 - 4.8e-06 27.0 11.6 0.03 15.1 0.3 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO06632.1 - 0.011 16.2 0.3 0.011 16.2 0.3 4.3 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KLO06632.1 - 0.044 13.8 0.2 0.044 13.8 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger Rpn3_C PF08375.11 KLO06632.1 - 0.15 12.5 0.4 0.32 11.4 0.4 1.4 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal FOXP-CC PF16159.5 KLO06632.1 - 0.26 11.9 2.9 19 6.0 0.1 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KLO06632.1 - 0.31 11.4 5.2 0.78 10.1 3.2 2.4 2 1 1 3 3 3 0 C2H2-type zinc ribbon IBR PF01485.21 KLO06632.1 - 0.42 10.9 5.7 0.3 11.3 1.8 2.5 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain PQ-loop PF04193.14 KLO06633.1 - 3.6e-22 77.9 0.9 3.3e-10 39.6 0.0 2.7 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KLO06633.1 - 0.0041 17.9 1.2 0.0064 17.3 1.2 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor BTB PF00651.31 KLO06635.1 - 0.015 15.6 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain MFS_1 PF07690.16 KLO06636.1 - 3.2e-26 92.1 21.4 3.2e-26 92.1 21.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KLO06636.1 - 2.4e-06 26.7 12.0 0.00048 19.1 1.4 2.4 2 1 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KLO06636.1 - 1.6e-05 23.9 14.0 2.4e-05 23.4 14.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF475 PF04332.15 KLO06637.1 - 0.19 11.4 0.0 0.29 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF475) zf-MYND PF01753.18 KLO06638.1 - 4.1e-10 39.6 16.0 1.2e-09 38.1 16.0 1.9 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KLO06638.1 - 0.068 13.5 7.9 0.23 11.8 7.9 1.9 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF676 PF05057.14 KLO06640.1 - 2.8e-05 23.7 0.1 7.7e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KLO06640.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KLO06640.1 - 0.0012 19.5 0.0 0.002 18.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family RRM_1 PF00076.22 KLO06640.1 - 0.0035 17.1 0.0 0.0085 15.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrolase_4 PF12146.8 KLO06640.1 - 0.044 13.0 0.1 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Cutinase PF01083.22 KLO06640.1 - 0.072 13.1 0.0 0.4 10.6 0.0 2.0 1 1 0 1 1 1 0 Cutinase DUF676 PF05057.14 KLO06641.1 - 0.0086 15.6 0.0 0.0098 15.4 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KLO06641.1 - 0.021 15.4 0.0 0.024 15.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO06641.1 - 0.11 11.7 0.1 0.39 9.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KLO06641.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF4837 PF16125.5 KLO06641.1 - 0.15 11.0 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) PGAP1 PF07819.13 KLO06642.1 - 1.5e-06 28.2 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KLO06642.1 - 0.00016 21.3 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KLO06642.1 - 0.00038 21.1 0.0 0.00052 20.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO06642.1 - 0.00046 19.5 0.0 0.00086 18.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KLO06642.1 - 0.005 17.0 0.0 0.012 15.7 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Palm_thioest PF02089.15 KLO06642.1 - 0.016 15.0 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LCAT PF02450.15 KLO06642.1 - 0.018 14.2 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF726 PF05277.12 KLO06642.1 - 0.051 12.5 0.1 0.097 11.6 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF726) PGAP1 PF07819.13 KLO06643.1 - 0.058 13.1 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 KLO06643.1 - 0.071 12.6 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KLO06643.1 - 0.074 12.3 0.1 0.68 9.2 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KLO06643.1 - 0.086 12.7 0.0 0.1 12.4 0.0 1.0 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KLO06643.1 - 0.15 12.6 0.1 0.21 12.2 0.1 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family PHF5 PF03660.14 KLO06644.1 - 3.1e-51 171.9 7.5 3.5e-51 171.8 7.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KLO06644.1 - 0.099 10.5 5.2 0.11 10.3 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KLO06644.1 - 3.2 7.9 13.6 6.1 6.9 1.2 2.9 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 KLO06644.1 - 9.6 6.6 16.6 0.44 10.9 1.9 2.6 1 1 1 2 2 2 0 C1 domain Peptidase_S10 PF00450.22 KLO06645.1 - 8.3e-61 206.6 0.1 2.4e-59 201.8 0.1 2.4 1 1 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KLO06645.1 - 0.039 13.2 0.0 0.65 9.2 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Casein PF00363.18 KLO06645.1 - 0.08 13.3 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 Casein DAP10 PF07213.11 KLO06646.1 - 0.011 15.7 0.1 0.22 11.5 0.1 2.4 2 0 0 2 2 2 0 DAP10 membrane protein PRIMA1 PF16101.5 KLO06646.1 - 0.33 11.0 6.0 1.8 8.6 5.0 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Evr1_Alr PF04777.13 KLO06647.1 - 3.8e-26 91.5 0.0 4.7e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family FAD_binding_3 PF01494.19 KLO06648.1 - 4.5e-22 78.8 0.0 1.1e-10 41.3 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KLO06648.1 - 7e-07 28.6 0.6 0.00057 19.1 0.1 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 KLO06648.1 - 7.9e-06 25.7 0.3 0.0051 16.4 0.1 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO06648.1 - 5.2e-05 22.6 0.0 0.00014 21.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KLO06648.1 - 6.7e-05 22.9 0.1 0.00019 21.5 0.1 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KLO06648.1 - 0.00072 18.5 0.2 0.018 13.9 0.1 2.5 3 0 0 3 3 3 1 Tryptophan halogenase SE PF08491.10 KLO06648.1 - 0.001 18.2 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 KLO06648.1 - 0.0055 16.9 0.6 0.018 15.3 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KLO06648.1 - 0.0084 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO06648.1 - 0.027 13.7 0.2 0.056 12.7 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KLO06648.1 - 0.027 15.0 0.3 0.6 10.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO06648.1 - 0.037 12.7 0.3 0.064 11.9 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KLO06648.1 - 0.12 11.4 1.4 0.24 10.4 1.4 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KLO06648.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A WD40 PF00400.32 KLO06649.1 - 5.8e-05 23.8 1.5 0.46 11.4 0.1 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat Nup160 PF11715.8 KLO06649.1 - 0.004 15.9 0.3 0.023 13.4 0.1 2.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 CPSF_A PF03178.15 KLO06649.1 - 0.093 12.0 0.1 3 7.1 0.1 2.5 1 1 0 1 1 1 0 CPSF A subunit region Smr PF01713.21 KLO06650.1 - 1.2e-07 32.0 0.2 5.9e-07 29.7 0.1 2.2 2 0 0 2 2 2 1 Smr domain AAA_13 PF13166.6 KLO06650.1 - 7.8e-05 21.5 2.9 7.8e-05 21.5 2.9 2.2 1 1 1 2 2 2 1 AAA domain DUF1771 PF08590.10 KLO06650.1 - 0.001 19.4 8.4 0.001 19.4 8.4 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) GAS PF13851.6 KLO06650.1 - 0.024 14.0 20.9 0.43 9.9 9.0 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AP_endonuc_2 PF01261.24 KLO06650.1 - 0.029 13.8 0.1 0.029 13.8 0.1 2.3 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel ERM PF00769.19 KLO06650.1 - 0.032 14.0 22.3 0.022 14.6 16.9 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family HTH_Tnp_1 PF01527.20 KLO06650.1 - 0.038 14.3 0.6 0.038 14.3 0.6 2.9 3 0 0 3 3 3 0 Transposase YlqD PF11068.8 KLO06650.1 - 2 8.8 10.2 4.3 7.7 2.5 2.6 1 1 1 2 2 2 0 YlqD protein Exonuc_VII_L PF02601.15 KLO06650.1 - 2.6 7.5 12.0 0.75 9.3 8.1 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Spc7 PF08317.11 KLO06650.1 - 4.4 6.1 20.2 13 4.6 20.1 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3421 PF11901.8 KLO06652.1 - 0.0079 16.2 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3421) Zip PF02535.22 KLO06653.1 - 4.1e-58 197.2 9.0 5.4e-58 196.8 9.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 KLO06654.1 - 4.9e-61 206.8 10.6 6.3e-61 206.4 10.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3017 PF11222.8 KLO06654.1 - 0.95 9.8 6.0 0.18 12.0 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3017) Bacteriocin_IId PF09221.10 KLO06654.1 - 2.1 8.6 4.7 0.64 10.2 0.2 2.4 3 0 0 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like DUF2781 PF10914.8 KLO06655.1 - 4.3e-22 79.1 3.3 2.6e-21 76.6 3.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) zf-HIT PF04438.16 KLO06656.1 - 3.9e-07 29.8 9.1 6.2e-07 29.2 9.1 1.3 1 0 0 1 1 1 1 HIT zinc finger Tnp_zf-ribbon_2 PF13842.6 KLO06656.1 - 1.2 10.0 4.2 2.1 9.2 4.2 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF4199 PF13858.6 KLO06657.1 - 0.54 10.6 13.7 4.3 7.7 6.7 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF4199) DUF4131 PF13567.6 KLO06657.1 - 4.2 7.0 8.4 2.6 7.7 3.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) p450 PF00067.22 KLO06658.1 - 0.0003 19.7 0.0 0.00032 19.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UvrD_C_2 PF13538.6 KLO06659.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain SH3_13 PF18335.1 KLO06659.1 - 0.1 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain PIF1 PF05970.14 KLO06660.1 - 9e-14 51.4 0.0 9.6e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KLO06660.1 - 1.6e-07 31.3 0.0 1.8e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO06660.1 - 0.00014 22.2 0.0 0.0003 21.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KLO06660.1 - 0.0011 18.2 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KLO06660.1 - 0.0045 17.4 0.0 0.0046 17.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO06660.1 - 0.012 15.9 0.1 0.018 15.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KLO06660.1 - 0.13 11.6 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KLO06660.1 - 0.16 11.8 0.1 0.19 11.6 0.1 1.4 1 1 0 1 1 1 0 NACHT domain GST_N_2 PF13409.6 KLO06663.1 - 5.7e-16 58.6 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KLO06663.1 - 3.7e-15 56.1 0.0 7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KLO06663.1 - 2.9e-07 30.7 0.1 6e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KLO06663.1 - 0.053 14.3 0.1 0.4 11.4 0.1 2.3 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain p450 PF00067.22 KLO06664.1 - 1.1e-66 225.5 0.0 1.4e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mis12 PF05859.12 KLO06665.1 - 7.2e-29 100.6 0.0 1.2e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein DUF2508 PF10704.9 KLO06665.1 - 0.01 16.0 0.2 0.026 14.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) MetOD2 PF18548.1 KLO06665.1 - 0.2 11.8 3.0 0.13 12.3 1.3 1.6 2 0 0 2 2 2 0 Metanogen output domain 2 NINJA_B PF16136.5 KLO06665.1 - 0.34 11.3 3.4 0.7 10.3 3.4 1.5 1 0 0 1 1 1 0 Putative nuclear localisation signal Lzipper-MIP1 PF14389.6 KLO06665.1 - 0.8 10.0 4.6 4.5 7.7 4.6 2.1 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF1479 PF07350.12 KLO06666.1 - 3.8e-128 427.8 0.0 4.3e-128 427.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KLO06666.1 - 0.008 16.5 0.1 1.2 9.3 0.1 2.7 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Prefoldin_2 PF01920.20 KLO06667.1 - 1.3e-16 60.4 6.1 1.6e-16 60.2 6.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.7 KLO06667.1 - 0.0029 17.7 5.9 0.0033 17.6 2.8 1.9 2 0 0 2 2 2 1 Tropomyosin like Formyl_trans_N PF00551.19 KLO06667.1 - 0.095 12.4 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Formyl transferase DUF5320 PF17253.2 KLO06667.1 - 0.11 13.5 0.5 0.24 12.5 0.1 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Jnk-SapK_ap_N PF09744.9 KLO06667.1 - 0.13 12.5 5.5 0.32 11.2 1.5 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Macoilin PF09726.9 KLO06667.1 - 0.34 9.4 5.0 0.79 8.2 1.6 1.9 1 1 1 2 2 2 0 Macoilin family Fib_alpha PF08702.10 KLO06667.1 - 0.39 10.9 5.3 2.9 8.0 2.0 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family EF-hand_6 PF13405.6 KLO06668.1 - 1.6e-09 36.9 0.4 0.00014 21.5 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KLO06668.1 - 1.7e-09 36.7 0.3 0.0006 19.2 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KLO06668.1 - 2.2e-08 34.4 1.0 2.2e-08 34.4 1.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KLO06668.1 - 5.8e-08 31.7 0.4 0.0051 16.3 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KLO06668.1 - 0.00093 19.0 0.9 0.012 15.4 0.6 2.2 1 1 1 2 2 2 1 EF-hand domain pair DUF1524 PF07510.11 KLO06668.1 - 0.16 11.9 0.2 0.16 11.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1524) DUF2489 PF10675.9 KLO06668.1 - 0.48 10.3 6.4 3.9 7.4 6.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2489) Dopey_N PF04118.14 KLO06669.1 - 5.8e-107 357.3 0.0 5.6e-106 354.1 0.0 2.6 2 0 0 2 2 2 1 Dopey, N-terminal DUF5320 PF17253.2 KLO06670.1 - 0.13 13.3 5.5 0.47 11.5 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5320) Tristanin_u2 PF16638.5 KLO06670.1 - 7.4 7.4 11.8 0.6 11.0 6.3 2.0 2 1 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers AT_hook PF02178.19 KLO06672.1 - 0.2 11.6 0.2 0.2 11.6 0.2 2.7 3 0 0 3 3 3 0 AT hook motif JAB PF01398.21 KLO06673.1 - 1.3e-10 41.3 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HAD_2 PF13419.6 KLO06674.1 - 2.6e-06 27.6 0.0 5.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO06674.1 - 0.00068 19.6 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.8 KLO06674.1 - 0.11 11.9 0.0 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) HAD_2 PF13419.6 KLO06675.1 - 7.3e-06 26.2 0.0 1.1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO06675.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like FSH1 PF03959.13 KLO06676.1 - 4.2e-46 157.3 0.0 5.4e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KLO06676.1 - 1.4e-05 24.9 0.0 0.0048 16.6 0.0 2.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold DLH PF01738.18 KLO06676.1 - 0.00084 19.0 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KLO06676.1 - 0.0042 16.4 0.0 0.07 12.4 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KLO06676.1 - 0.012 15.1 0.0 0.045 13.2 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family CHCH PF06747.13 KLO06677.1 - 1.3e-07 31.6 4.0 2.6e-07 30.6 4.0 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KLO06677.1 - 0.039 14.4 3.0 0.066 13.6 3.0 1.4 1 0 0 1 1 1 0 GCK domain DUF1932 PF09130.11 KLO06678.1 - 4.2e-11 42.7 0.0 9.9e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.17 KLO06678.1 - 0.00052 20.6 0.0 0.0042 17.6 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KLO06678.1 - 0.025 14.8 0.0 0.14 12.3 0.0 2.3 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AvrRpt-cleavage PF05627.11 KLO06678.1 - 0.19 11.1 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Cleavage site for pathogenic type III effector avirulence factor Avr F-box-like PF12937.7 KLO06680.1 - 5.7e-06 26.1 0.6 0.00021 21.1 0.0 2.6 2 0 0 2 2 2 1 F-box-like Bclx_interact PF08945.10 KLO06680.1 - 0.05 13.4 0.3 0.12 12.1 0.3 1.6 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain CAP_assoc_N PF14504.6 KLO06680.1 - 0.29 10.9 1.1 0.48 10.2 1.1 1.2 1 0 0 1 1 1 0 CAP-associated N-terminal F-box-like PF12937.7 KLO06681.1 - 0.00017 21.4 0.1 0.0004 20.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO06682.1 - 8.6e-06 25.6 1.1 1.6e-05 24.7 0.1 2.0 2 0 0 2 2 2 1 F-box-like DUF3517 PF12030.8 KLO06682.1 - 0.039 12.9 0.1 0.063 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) F-box-like PF12937.7 KLO06683.1 - 2.3e-06 27.4 7.3 2.6e-06 27.2 0.3 3.3 4 0 0 4 4 4 1 F-box-like LRR_4 PF12799.7 KLO06683.1 - 0.024 15.1 2.1 2.5 8.7 0.1 4.6 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) DUF3517 PF12030.8 KLO06683.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) Dr_adhesin PF12393.8 KLO06685.1 - 0.63 10.4 3.4 4.8 7.6 0.3 2.2 2 0 0 2 2 2 0 Dr family adhesin F-box-like PF12937.7 KLO06687.1 - 2.6e-09 36.8 0.2 1.4e-08 34.5 0.0 2.4 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO06687.1 - 0.00087 19.6 3.6 0.74 10.3 0.3 4.4 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KLO06687.1 - 0.0033 17.4 0.4 0.78 10.0 0.0 3.2 2 0 0 2 2 2 1 Leucine Rich repeat F-box PF00646.33 KLO06687.1 - 0.25 11.2 4.3 20 5.2 0.0 3.6 3 0 0 3 3 3 0 F-box domain CGGC PF08821.11 KLO06687.1 - 3.7 7.8 5.5 2.5 8.3 1.6 2.3 2 1 1 3 3 3 0 CGGC domain zf-RING_UBOX PF13445.6 KLO06688.1 - 2.8e-07 30.4 4.2 2.8e-07 30.4 4.2 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KLO06688.1 - 7.7e-07 28.8 3.3 7.7e-07 28.8 3.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO06688.1 - 1.9e-06 28.1 9.9 2.7e-06 27.6 3.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KLO06688.1 - 2.5e-06 27.2 3.1 2.5e-06 27.2 3.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KLO06688.1 - 0.00023 21.2 5.8 0.00028 21.0 2.0 2.5 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KLO06688.1 - 0.00061 19.6 1.9 0.00061 19.6 1.9 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KLO06688.1 - 0.0019 18.1 9.8 0.0067 16.4 5.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KLO06688.1 - 0.0039 17.0 9.8 0.056 13.3 4.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KLO06688.1 - 0.032 13.9 7.9 0.031 13.9 5.4 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KLO06688.1 - 0.11 12.4 8.5 0.13 12.1 3.7 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KLO06688.1 - 0.16 12.2 6.7 3.9 7.7 4.6 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-H2C2_2 PF13465.6 KLO06688.1 - 0.18 12.3 1.2 0.83 10.2 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DZR PF12773.7 KLO06688.1 - 0.19 11.8 5.5 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-rbx1 PF12678.7 KLO06688.1 - 0.39 11.0 9.0 0.41 11.0 5.4 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain ECH_1 PF00378.20 KLO06689.1 - 1.2e-84 283.6 0.1 1.5e-84 283.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KLO06689.1 - 1.7e-38 133.0 0.1 3e-35 122.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase AARP2CN PF08142.12 KLO06690.1 - 0.017 15.2 0.0 0.038 14.1 0.0 1.6 1 1 0 1 1 1 0 AARP2CN (NUC121) domain Crisp PF08562.10 KLO06690.1 - 0.033 14.8 1.7 0.081 13.5 0.9 2.0 2 0 0 2 2 2 0 Crisp Abhydrolase_3 PF07859.13 KLO06691.1 - 6.6e-20 71.9 0.3 4e-18 66.1 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO06691.1 - 1e-13 50.9 0.0 6e-09 35.2 0.0 3.0 3 0 0 3 3 3 3 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KLO06691.1 - 0.0054 17.4 3.4 0.0076 16.9 3.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pap_E4 PF02711.14 KLO06693.1 - 4.1 8.4 14.3 16 6.5 3.8 2.9 2 0 0 2 2 2 0 E4 protein F-box-like PF12937.7 KLO06694.1 - 3.6e-09 36.4 0.1 1.3e-08 34.6 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO06694.1 - 0.00062 19.6 0.1 0.0021 17.9 0.1 2.0 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.16 KLO06695.1 - 2.7e-21 75.9 37.7 2.7e-21 75.9 37.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.25 KLO06696.1 - 2.1e-41 142.1 0.0 3.4e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO06696.1 - 3.4e-38 131.4 0.0 4.9e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PACT_coil_coil PF10495.9 KLO06696.1 - 3.1e-07 30.9 10.8 0.0032 18.0 0.2 3.7 3 1 1 4 4 3 2 Pericentrin-AKAP-450 domain of centrosomal targeting protein Kinase-like PF14531.6 KLO06696.1 - 2.2e-05 23.9 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO06696.1 - 0.00095 18.6 0.0 0.0031 16.9 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CysG_dimeriser PF10414.9 KLO06696.1 - 0.01 15.5 1.9 2 8.2 0.0 3.3 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region DUF309 PF03745.14 KLO06696.1 - 0.021 14.5 2.2 1.1 9.0 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF309) RIO1 PF01163.22 KLO06696.1 - 0.039 13.5 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.9 KLO06696.1 - 0.13 11.7 0.0 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF3350 PF11830.8 KLO06696.1 - 0.64 10.4 4.2 7.6 6.9 0.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF3350) CaATP_NAI PF12515.8 KLO06696.1 - 10 5.9 10.1 6.1 6.6 0.1 3.4 2 1 1 3 3 3 0 Ca2+-ATPase N terminal autoinhibitory domain adh_short PF00106.25 KLO06698.1 - 7e-20 71.3 1.4 5.2e-18 65.2 1.4 2.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO06698.1 - 2.2e-12 47.0 3.3 5.5e-07 29.4 1.2 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO06698.1 - 0.00035 20.5 1.1 0.00035 20.5 1.1 1.5 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 KLO06698.1 - 0.001 18.4 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KLO06698.1 - 0.0024 17.4 0.0 0.68 9.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KLO06698.1 - 0.015 15.2 1.0 0.022 14.6 1.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 KLO06698.1 - 0.033 14.0 1.4 0.05 13.4 1.4 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF3593 PF12159.8 KLO06699.1 - 0.58 10.2 6.6 5.5 7.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) Pro-kuma_activ PF09286.11 KLO06700.1 - 2.7e-39 134.7 0.3 3.2e-38 131.2 0.1 2.4 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KLO06700.1 - 3.7e-08 33.0 2.3 5.7e-08 32.4 2.3 1.3 1 0 0 1 1 1 1 Subtilase family DNA_pol_A_exo1 PF01612.20 KLO06701.1 - 8.4e-12 45.1 0.0 5.4e-05 23.0 0.0 2.4 3 0 0 3 3 3 2 3'-5' exonuclease DUF4577 PF15145.6 KLO06702.1 - 0.051 13.6 0.6 0.051 13.6 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) Orf78 PF06024.12 KLO06702.1 - 0.078 13.3 0.2 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 Orf78 (ac78) SCIMP PF15050.6 KLO06702.1 - 0.14 12.6 0.8 0.55 10.7 0.0 1.9 2 0 0 2 2 2 0 SCIMP protein EphA2_TM PF14575.6 KLO06702.1 - 0.41 11.5 2.0 1.8 9.5 0.8 2.2 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain F-box-like PF12937.7 KLO06703.1 - 0.00044 20.1 0.1 0.0012 18.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like ODAPH PF15848.5 KLO06703.1 - 5.7 7.4 6.6 1.7 9.1 2.7 2.2 2 1 0 2 2 2 0 Odontogenesis associated phosphoprotein F-box-like PF12937.7 KLO06704.1 - 1.2e-07 31.5 0.0 4.4e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO06704.1 - 0.076 12.9 0.8 1.5 8.8 0.8 2.8 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO06706.1 - 1.4e-08 34.5 0.0 4e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KLO06706.1 - 0.19 12.4 3.4 84 4.3 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat F-box-like PF12937.7 KLO06707.1 - 2.3e-07 30.6 0.0 6.3e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like PIF1 PF05970.14 KLO06708.1 - 2.2e-24 86.3 0.0 2.7e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KLO06708.1 - 1.6e-13 50.8 0.0 2.1e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO06708.1 - 2.8e-11 44.0 0.0 5.6e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KLO06708.1 - 0.0007 19.4 0.3 0.002 17.9 0.3 1.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KLO06708.1 - 0.0013 19.2 0.0 0.0014 19.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO06708.1 - 0.0026 18.0 0.3 0.016 15.5 0.3 2.0 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KLO06708.1 - 0.0041 17.0 0.1 0.11 12.3 0.1 2.1 1 1 1 2 2 2 2 Helicase AAA PF00004.29 KLO06708.1 - 0.047 14.1 0.0 0.065 13.7 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KLO06708.1 - 0.072 12.9 1.2 0.95 9.2 0.1 2.6 2 1 1 3 3 3 0 AAA domain KAP_NTPase PF07693.14 KLO06708.1 - 0.1 11.8 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Torsin PF06309.11 KLO06708.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Torsin ResIII PF04851.15 KLO06708.1 - 0.12 12.3 0.4 0.46 10.5 0.1 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit ParA PF10609.9 KLO06708.1 - 0.27 10.6 1.7 0.99 8.8 1.2 1.8 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Helitron_like_N PF14214.6 KLO06710.1 - 3.1e-30 105.8 0.1 8.2e-30 104.4 0.0 1.8 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Spindle_Spc25 PF08234.12 KLO06710.1 - 0.05 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 F-box-like PF12937.7 KLO06713.1 - 1.4e-09 37.7 0.0 3.6e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO06713.1 - 0.004 17.0 0.0 0.023 14.6 0.0 2.3 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO06715.1 - 2e-07 30.8 0.3 7e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO06716.1 - 8.9e-09 35.1 0.0 2.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO06716.1 - 0.0069 16.2 0.6 0.11 12.5 0.6 2.5 1 1 0 1 1 1 1 F-box domain KDZ PF18758.1 KLO06717.1 - 2.6e-46 158.0 0.0 5.3e-46 157.0 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO06717.1 - 3.6e-30 104.3 0.0 9.5e-30 102.9 0.0 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO06717.1 - 1.6e-07 31.4 0.1 4.6e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KLO06717.1 - 3.3e-05 23.7 0.1 0.00011 22.0 0.1 1.9 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases D5_N PF08706.11 KLO06717.1 - 2.2 8.5 6.2 2.2 8.5 0.5 2.7 2 0 0 2 2 2 0 D5 N terminal like Tet_JBP PF12851.7 KLO06718.1 - 7e-07 28.9 0.0 4.7e-05 22.9 0.0 2.0 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily HMMR_C PF15908.5 KLO06718.1 - 0.059 13.6 0.4 0.082 13.2 0.4 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal SQS_PSY PF00494.19 KLO06719.1 - 1.1e-31 110.4 0.0 1.5e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Pkinase_fungal PF17667.1 KLO06720.1 - 3e-52 177.8 0.7 1.3e-51 175.7 0.2 2.3 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 KLO06720.1 - 1.3e-05 24.7 0.2 4.9e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KLO06720.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KLO06720.1 - 0.094 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO06721.1 - 3.3e-57 194.1 0.0 1.6e-56 191.8 0.0 2.0 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO06721.1 - 0.00023 20.6 0.1 0.00044 19.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KLO06721.1 - 0.012 15.3 0.4 0.056 13.0 0.1 2.1 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KLO06721.1 - 0.027 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KLO06722.1 - 3.6e-54 184.1 0.3 5.4e-30 104.5 0.0 2.6 3 0 0 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 KLO06722.1 - 4.4e-08 32.8 0.0 7.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KLO06722.1 - 0.0023 17.3 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KLO06722.1 - 0.041 13.2 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Gal-bind_lectin PF00337.22 KLO06722.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Galactoside-binding lectin MFS_1 PF07690.16 KLO06723.1 - 1.9e-26 92.8 25.4 1.9e-26 92.8 25.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO06723.1 - 0.00025 20.1 0.5 0.00025 20.1 0.5 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter Adaptin_N PF01602.20 KLO06725.1 - 2.2e-121 406.0 5.8 2.7e-121 405.7 5.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KLO06725.1 - 9e-55 185.1 4.1 4.4e-53 179.6 0.3 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KLO06725.1 - 4.3e-15 55.9 1.8 7.7e-06 26.2 0.3 4.6 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.22 KLO06725.1 - 5.2e-08 32.5 4.6 0.14 12.5 0.0 5.9 7 0 0 7 7 7 3 HEAT repeat Cnd3 PF12719.7 KLO06725.1 - 0.00016 21.0 0.2 0.093 11.9 0.0 2.3 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 KLO06725.1 - 0.00016 21.6 0.9 0.12 12.5 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KLO06725.1 - 0.0037 17.4 3.0 7.6 6.8 0.3 3.8 2 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KLO06725.1 - 0.0037 16.9 0.0 0.49 9.9 0.0 2.6 2 0 0 2 2 2 1 CLASP N terminal Nipped-B_C PF12830.7 KLO06725.1 - 0.0053 16.7 0.1 1.4 8.8 0.0 3.0 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus DUF5578 PF17741.1 KLO06725.1 - 0.029 13.8 0.4 15 4.9 0.0 3.4 3 1 1 4 4 4 0 Family of unknown function (DUF5578) DUF4477 PF14780.6 KLO06726.1 - 5.9e-13 48.9 0.0 7.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) eIF3m_C_helix PF18005.1 KLO06726.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix CHCH PF06747.13 KLO06727.1 - 7.7e-05 22.7 0.3 0.00014 21.9 0.3 1.5 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KLO06727.1 - 0.0025 17.8 0.9 0.0029 17.6 0.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.8 KLO06727.1 - 0.13 12.6 1.8 0.26 11.7 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) UQ_con PF00179.26 KLO06728.1 - 1.2e-18 67.1 0.0 2.4e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RanBP PF00641.18 KLO06728.1 - 0.055 12.8 0.3 0.055 12.8 0.3 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PRP21_like_P PF12230.8 KLO06730.1 - 3.6e-47 161.0 16.0 3.6e-47 161.0 16.0 2.3 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KLO06730.1 - 1.3e-28 98.7 4.3 1.3e-13 50.7 0.1 3.1 3 0 0 3 3 3 2 Surp module ubiquitin PF00240.23 KLO06730.1 - 2.5e-06 27.2 0.0 5.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 KLO06730.1 - 0.00049 19.6 0.2 0.001 18.6 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Rad60-SLD PF11976.8 KLO06730.1 - 0.025 14.4 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like L31 PF09784.9 KLO06731.1 - 2.8e-42 143.3 0.1 3.1e-42 143.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 CMS1 PF14617.6 KLO06732.1 - 4.6e-69 232.6 0.1 5.2e-69 232.4 0.1 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RNase_T PF00929.24 KLO06733.1 - 6.2e-15 56.1 0.0 5.6e-14 53.0 0.0 2.0 1 1 0 1 1 1 1 Exonuclease MoCF_biosynth PF00994.24 KLO06735.1 - 3.8e-33 114.2 0.0 8.8e-33 113.0 0.0 1.6 2 0 0 2 2 2 1 Probable molybdopterin binding domain CinA_KH PF18146.1 KLO06735.1 - 0.019 15.1 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain DUF917 PF06032.12 KLO06736.1 - 2.2e-112 375.3 0.0 3.3e-112 374.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KLO06736.1 - 5.2e-29 101.4 8.6 1.4e-25 90.2 4.6 3.3 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KLO06736.1 - 4.9e-24 85.0 7.9 4.7e-23 81.8 0.2 3.4 3 2 1 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.20 KLO06736.1 - 2.1e-06 27.4 3.7 2.7e-05 23.8 0.6 2.6 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 KLO06736.1 - 5.2e-05 22.9 0.5 0.00014 21.4 0.5 1.8 1 0 0 1 1 1 1 ROK family FtsA PF14450.6 KLO06736.1 - 7.8e-05 23.0 4.8 0.027 14.9 0.1 3.7 3 0 0 3 3 3 1 Cell division protein FtsA MutL PF13941.6 KLO06736.1 - 8.4e-05 21.3 5.6 0.026 13.1 0.0 2.5 3 0 0 3 3 3 2 MutL protein IstB_IS21 PF01695.17 KLO06736.1 - 0.00043 20.1 0.0 0.00085 19.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein FGGY_N PF00370.21 KLO06736.1 - 0.0086 15.7 0.5 0.017 14.7 0.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain StbA PF06406.11 KLO06736.1 - 0.022 14.0 0.1 6.9 5.8 0.0 2.4 2 0 0 2 2 2 0 StbA protein Smg4_UPF3 PF03467.15 KLO06737.1 - 2.8e-50 170.7 0.1 2.8e-50 170.7 0.1 2.3 2 0 0 2 2 2 1 Smg-4/UPF3 family CiPC PF15800.5 KLO06737.1 - 0.6 9.8 15.4 1 9.0 15.4 1.3 1 0 0 1 1 1 0 Clock interacting protein circadian Cytomega_UL20A PF05984.12 KLO06737.1 - 0.67 10.3 5.1 2.2 8.6 5.1 1.9 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein MCM PF00493.23 KLO06738.1 - 2.5e-96 321.1 0.0 4.4e-96 320.3 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KLO06738.1 - 1.3e-35 122.0 0.2 2.1e-35 121.3 0.2 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KLO06738.1 - 1.7e-28 98.9 1.9 2e-28 98.6 0.6 1.8 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KLO06738.1 - 1.9e-18 66.9 1.3 4.8e-18 65.7 0.2 2.2 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.14 KLO06738.1 - 9e-08 32.2 0.0 2.5e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KLO06738.1 - 1.6e-07 30.9 0.0 5.9e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KLO06738.1 - 0.00046 20.1 0.0 0.0054 16.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KLO06738.1 - 0.0013 18.4 0.0 0.73 9.5 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_16 PF13191.6 KLO06738.1 - 0.0093 16.4 0.1 0.077 13.4 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain DUF4954 PF16314.5 KLO06738.1 - 0.1 10.7 0.0 0.22 9.6 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) LRR_4 PF12799.7 KLO06739.1 - 8.4 7.0 29.7 1.6 9.3 0.5 8.9 5 3 5 10 10 10 0 Leucine Rich repeats (2 copies) GPI-anchored PF10342.9 KLO06740.1 - 4.2e-07 30.6 0.3 4.2e-07 30.6 0.3 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ORC_WH_C PF18137.1 KLO06741.1 - 1.1e-37 129.3 0.0 2.3e-37 128.2 0.0 1.6 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 KLO06741.1 - 1.3e-24 87.0 0.0 2e-23 83.0 0.0 2.3 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus Aa_trans PF01490.18 KLO06742.1 - 1.1e-26 93.5 31.6 1.6e-26 93.0 31.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Asp_Glu_race_2 PF14669.6 KLO06742.1 - 0.12 12.0 4.0 3.6 7.2 0.2 2.2 2 0 0 2 2 2 0 Putative aspartate racemase SLATT_5 PF18160.1 KLO06742.1 - 4.6 6.5 7.1 0.28 10.5 1.3 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 SYF2 PF08231.12 KLO06744.1 - 3.2e-59 199.9 18.1 3.2e-59 199.9 18.1 2.5 2 1 0 2 2 2 1 SYF2 splicing factor Lactococcin PF04369.13 KLO06744.1 - 0.023 14.8 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 Lactococcin-like family Mitofilin PF09731.9 KLO06744.1 - 6.6 5.4 36.4 1.2 7.9 32.2 1.6 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Pyr_redox_2 PF07992.14 KLO06745.1 - 9.1e-47 159.7 0.0 1.6e-46 158.9 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO06745.1 - 2.9e-11 43.8 0.0 4.3e-09 36.8 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO06745.1 - 0.0047 16.2 0.6 2.5 7.3 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KLO06745.1 - 0.19 10.7 0.0 0.43 9.6 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Aa_trans PF01490.18 KLO06746.1 - 4.5e-25 88.2 32.8 6.4e-25 87.7 32.8 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SLATT_5 PF18160.1 KLO06746.1 - 0.71 9.2 3.3 0.84 8.9 1.4 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Asp_Glu_race_2 PF14669.6 KLO06746.1 - 0.74 9.4 4.6 2.3 7.9 0.8 2.2 2 0 0 2 2 2 0 Putative aspartate racemase DLH PF01738.18 KLO06747.1 - 2.1e-22 79.7 0.0 2.7e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KLO06747.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 KLO06748.1 - 3.2e-22 79.2 0.0 3.9e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 KLO06749.1 - 2.9e-22 79.3 0.0 3.6e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family SH3_2 PF07653.17 KLO06752.1 - 0.00047 19.8 0.0 0.00065 19.3 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain RabGAP-TBC PF00566.18 KLO06753.1 - 1.8e-33 116.0 0.0 2.5e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.7 KLO06754.1 - 0.00053 19.8 0.0 0.0017 18.2 0.0 1.9 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.25 KLO06755.1 - 3.6e-69 233.0 0.0 2.3e-67 227.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO06755.1 - 1.9e-35 122.4 0.0 2.4e-32 112.2 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO06755.1 - 1.2e-06 27.6 0.2 2.3e-06 26.7 0.2 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO06755.1 - 0.00017 21.0 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SR-25 PF10500.9 KLO06755.1 - 0.0033 17.1 0.2 0.0051 16.5 0.2 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Kdo PF06293.14 KLO06755.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KLO06755.1 - 0.028 13.9 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PNP_UDP_1 PF01048.20 KLO06757.1 - 2.8e-23 82.4 0.0 5.4e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily Imm26 PF15428.6 KLO06759.1 - 0.17 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 26 Fasciclin PF02469.22 KLO06763.1 - 7e-26 90.9 1.7 3.7e-12 46.6 0.0 4.1 4 0 0 4 4 4 4 Fasciclin domain Phage_holin_T PF11031.8 KLO06764.1 - 0.25 10.8 0.0 0.3 10.5 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T holin Glyco_hydro_16 PF00722.21 KLO06765.1 - 2.1e-19 69.7 0.0 3.9e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 NACHT PF05729.12 KLO06766.1 - 5e-11 42.8 0.1 8e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO06766.1 - 6.5e-09 36.4 0.3 1.1e-08 35.6 0.3 1.4 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KLO06766.1 - 8.8e-05 21.8 0.1 0.00022 20.5 0.1 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KLO06766.1 - 0.0031 17.8 0.0 0.011 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KLO06766.1 - 0.0031 17.9 0.0 0.01 16.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KLO06766.1 - 0.0087 16.0 0.7 0.049 13.5 0.3 2.2 1 1 1 2 2 2 1 Adenylylsulphate kinase KAP_NTPase PF07693.14 KLO06766.1 - 0.014 14.7 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_14 PF13173.6 KLO06766.1 - 0.13 12.3 0.0 12 5.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF2202 PF09968.9 KLO06767.1 - 0.11 12.3 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) Peptidase_S10 PF00450.22 KLO06769.1 - 3.4e-74 250.7 0.5 6.2e-74 249.9 0.5 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase AA_permease PF00324.21 KLO06770.1 - 8.9e-111 370.8 34.2 1e-110 370.6 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KLO06770.1 - 3.1e-29 102.0 41.1 3.8e-29 101.8 41.1 1.0 1 0 0 1 1 1 1 Amino acid permease Importin_rep_4 PF18808.1 KLO06772.1 - 1.3e-14 54.3 0.4 1.3e-14 54.3 0.4 2.4 3 0 0 3 3 1 1 Importin repeat HEAT PF02985.22 KLO06772.1 - 4.1e-14 51.5 1.1 9e-05 22.4 0.0 7.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KLO06772.1 - 2.8e-13 50.1 14.8 9.1e-06 26.1 0.0 9.0 7 2 3 10 10 9 3 HEAT-like repeat HEAT_2 PF13646.6 KLO06772.1 - 8.7e-09 35.7 9.5 0.00027 21.3 0.0 6.2 4 2 2 6 6 5 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KLO06772.1 - 2.7e-08 34.3 0.0 0.0032 18.0 0.0 4.4 4 1 1 5 5 3 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 KLO06772.1 - 3.8e-05 23.5 4.9 0.0063 16.3 0.0 4.7 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis DUF4042 PF13251.6 KLO06772.1 - 7.3e-05 22.5 0.0 1.2 8.8 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4042) DUF3385 PF11865.8 KLO06772.1 - 0.00011 22.2 0.0 1.2 9.0 0.0 4.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KLO06772.1 - 0.00071 19.7 0.0 0.0059 16.7 0.0 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KLO06772.1 - 0.0051 15.4 0.0 1.6 7.2 0.0 3.3 2 1 1 3 3 3 1 Adaptin N terminal region Cnd3 PF12719.7 KLO06772.1 - 0.021 14.0 3.2 6.6 5.8 0.1 4.4 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain TPR_14 PF13428.6 KLO06772.1 - 0.046 14.5 0.1 0.89 10.5 0.0 3.3 3 0 0 3 3 1 0 Tetratricopeptide repeat CLASP_N PF12348.8 KLO06772.1 - 0.065 12.8 0.1 6 6.4 0.0 3.5 4 0 0 4 4 4 0 CLASP N terminal MID_MedPIWI PF18296.1 KLO06772.1 - 0.18 11.6 4.2 0.68 9.7 1.4 2.8 1 1 1 2 2 2 0 MID domain of medPIWI Tti2 PF10521.9 KLO06772.1 - 0.21 11.1 3.4 0.58 9.7 0.0 3.3 4 1 0 5 5 4 0 Tti2 family MMS19_C PF12460.8 KLO06772.1 - 0.62 9.1 4.9 3.3 6.7 0.1 3.1 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal CAP_N PF01213.19 KLO06772.1 - 1 8.8 4.7 3 7.3 0.1 2.8 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal DUF4614 PF15391.6 KLO06772.1 - 1.3 9.0 5.6 3.4 7.6 5.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CDK2AP PF09806.9 KLO06772.1 - 1.6 8.7 7.5 2.7 8.0 1.7 2.7 3 0 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein Pox_F17 PF04767.12 KLO06773.1 - 0.04 14.4 1.9 0.04 14.4 1.9 1.9 2 0 0 2 2 2 0 DNA-binding 11 kDa phosphoprotein FAD_binding_3 PF01494.19 KLO06774.1 - 1.4e-25 90.3 0.1 4e-25 88.8 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO06774.1 - 4.2e-10 39.3 0.1 3.6e-06 26.4 0.1 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KLO06774.1 - 3e-06 26.5 0.7 0.0047 16.0 0.3 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 KLO06774.1 - 7.9e-06 25.2 1.0 7.9e-06 25.2 1.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KLO06774.1 - 9.3e-06 25.8 0.7 4.2e-05 23.7 0.7 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KLO06774.1 - 2.6e-05 23.1 0.1 0.0001 21.2 0.1 1.8 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KLO06774.1 - 5.8e-05 22.6 2.7 0.2 10.9 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 KLO06774.1 - 0.00012 21.8 2.2 0.00012 21.8 2.2 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KLO06774.1 - 0.00012 22.5 0.0 0.0057 17.2 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KLO06774.1 - 0.00032 19.9 0.1 0.00073 18.7 0.3 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KLO06774.1 - 0.00052 19.0 0.4 0.41 9.4 0.4 2.5 3 0 0 3 3 3 2 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KLO06774.1 - 0.0023 17.2 0.3 0.0045 16.3 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KLO06774.1 - 0.011 15.2 0.9 0.036 13.4 1.2 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KLO06774.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KLO06774.1 - 0.065 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 KLO06774.1 - 0.072 12.7 0.1 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox_3 PF13738.6 KLO06774.1 - 0.17 11.1 0.0 0.54 9.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO06774.1 - 0.21 10.8 0.1 0.37 10.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family zf-MYND PF01753.18 KLO06775.1 - 4.5e-07 29.8 17.5 1.1e-06 28.6 17.5 1.7 1 0 0 1 1 1 1 MYND finger DUF4224 PF13986.6 KLO06775.1 - 0.037 13.9 0.2 0.34 10.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Peptidase_S24 PF00717.23 KLO06776.1 - 1.8e-08 34.2 0.0 3.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KLO06776.1 - 3.5e-07 30.1 0.0 0.00037 20.3 0.0 2.6 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 GST_N_2 PF13409.6 KLO06776.1 - 0.033 14.5 0.0 2.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Cas_VVA1548 PF09652.10 KLO06776.1 - 0.084 13.1 0.0 5.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) TPR_2 PF07719.17 KLO06777.1 - 1.4e-06 28.0 0.1 0.15 12.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KLO06777.1 - 3.8e-06 26.5 0.2 0.084 12.7 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KLO06777.1 - 0.00018 22.0 0.1 1.2 10.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KLO06777.1 - 0.0074 16.2 0.0 0.31 11.2 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KLO06777.1 - 0.043 14.1 0.1 10 6.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KLO06777.1 - 0.053 14.0 0.2 1.5 9.4 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KLO06777.1 - 0.1 13.3 0.2 4.5 8.0 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase_fungal PF17667.1 KLO06778.1 - 9.8e-91 304.5 0.0 9.8e-91 304.5 0.0 2.0 2 1 1 3 3 3 1 Fungal protein kinase DUF465 PF04325.13 KLO06778.1 - 0.0087 16.1 0.4 0.029 14.4 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF465) CutC PF03932.14 KLO06779.1 - 2.4e-48 164.3 0.1 2.9e-48 164.1 0.1 1.1 1 0 0 1 1 1 1 CutC family DUF3783 PF12646.7 KLO06780.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) TMEM239 PF15841.5 KLO06781.1 - 0.76 9.7 5.7 0.075 12.9 0.8 1.8 2 0 0 2 2 2 0 Transmembrane protein 239 family SUR7 PF06687.12 KLO06783.1 - 7.5e-18 64.9 14.1 1.1e-17 64.4 14.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family TMEM52 PF14979.6 KLO06783.1 - 0.44 10.5 2.2 0.39 10.6 0.1 1.9 2 0 0 2 2 2 0 Transmembrane 52 LRR_4 PF12799.7 KLO06784.1 - 0.096 13.1 0.2 7.6 7.1 0.0 3.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO06785.1 - 1.8e-07 30.9 0.3 1.8e-07 30.9 0.3 2.3 3 0 0 3 3 3 1 F-box-like HipN PF18253.1 KLO06785.1 - 0.026 14.2 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain Poxvirus PF06227.12 KLO06785.1 - 0.032 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 dsDNA Poxvirus LRR_4 PF12799.7 KLO06785.1 - 0.038 14.4 3.6 2.3 8.8 0.1 4.5 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO06786.1 - 0.00023 21.0 0.1 0.00023 21.0 0.1 2.4 2 0 0 2 2 2 1 F-box-like DUF3152 PF11350.8 KLO06786.1 - 0.058 13.1 0.1 0.097 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) MitMem_reg PF13012.6 KLO06786.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Tri3 PF07428.11 KLO06787.1 - 0.0039 16.2 0.0 0.0059 15.6 0.0 1.2 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 O-FucT PF10250.9 KLO06788.1 - 7.3e-14 52.2 0.0 1.5e-12 47.9 0.0 2.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 KLO06788.1 - 0.053 12.7 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 11 TPT PF03151.16 KLO06789.1 - 3.4e-09 36.5 21.7 7.5e-09 35.3 21.7 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family UbiA PF01040.18 KLO06791.1 - 1.8e-41 142.1 19.3 2.4e-41 141.7 19.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF973 PF06157.11 KLO06791.1 - 0.23 10.5 2.9 0.11 11.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF973) DUF5510 PF17629.2 KLO06791.1 - 1.7 8.6 5.1 0.45 10.5 0.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5510) Methyltransf_2 PF00891.18 KLO06792.1 - 0.00062 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KLO06792.1 - 0.033 14.9 0.0 1.1 10.1 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Dimerisation2 PF16864.5 KLO06792.1 - 0.068 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Dimerisation PF08100.11 KLO06792.1 - 0.091 12.8 0.2 0.23 11.5 0.1 1.8 2 0 0 2 2 2 0 Dimerisation domain NAD_binding_4 PF07993.12 KLO06793.1 - 2.1e-34 118.9 0.0 3.2e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KLO06793.1 - 1.5e-28 99.5 0.0 2.4e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KLO06793.1 - 9.2e-06 25.3 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KLO06793.1 - 7.3e-05 23.0 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site CLP1_P PF16575.5 KLO06793.1 - 0.026 14.3 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NAD_binding_4 PF07993.12 KLO06794.1 - 9.5e-32 110.2 0.0 1.5e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KLO06794.1 - 2e-27 95.9 0.0 9e-27 93.7 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KLO06794.1 - 2.6e-08 33.6 0.0 5.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KLO06794.1 - 0.00069 19.9 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KLO06794.1 - 0.048 13.6 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 KR domain SUV3_C PF12513.8 KLO06795.1 - 0.26 11.2 0.8 0.86 9.6 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal FIN1 PF17300.2 KLO06795.1 - 0.33 10.4 4.6 0.73 9.3 4.6 1.6 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 p450 PF00067.22 KLO06796.1 - 5.9e-74 249.5 0.0 6.6e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MADF_DNA_bdg PF10545.9 KLO06796.1 - 0.37 11.1 3.0 6.4 7.2 0.0 3.1 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4896 PF16237.5 KLO06797.1 - 0.037 13.9 1.6 0.15 11.9 1.6 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4896) Peptidase_C98 PF15499.6 KLO06797.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Abhydrolase_3 PF07859.13 KLO06798.1 - 1.2e-10 41.6 0.0 3e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KLO06798.1 - 3.5e-07 29.5 0.0 3.8e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 KLO06798.1 - 1.2e-06 27.9 0.0 3e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KLO06798.1 - 0.0011 19.6 0.3 0.0018 18.9 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KLO06798.1 - 0.0075 15.8 0.0 0.063 12.7 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KLO06798.1 - 0.01 14.8 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_1 PF00561.20 KLO06798.1 - 0.026 14.2 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KLO06798.1 - 0.051 13.3 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 KLO06798.1 - 0.071 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.13 KLO06798.1 - 0.15 10.5 0.4 0.55 8.7 0.1 1.9 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II FAD_binding_3 PF01494.19 KLO06801.1 - 9e-84 281.7 0.0 1.3e-83 281.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KLO06801.1 - 1.5e-28 99.9 0.0 3e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KLO06801.1 - 1.2e-05 24.3 0.8 1.7e-05 23.7 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KLO06801.1 - 2.4e-05 23.6 1.9 4.5e-05 22.7 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO06801.1 - 0.00079 18.7 0.2 0.002 17.5 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO06801.1 - 0.0013 18.9 0.1 0.0032 17.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KLO06801.1 - 0.0024 18.4 0.1 0.028 15.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KLO06801.1 - 0.0025 17.2 0.1 0.0042 16.4 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KLO06801.1 - 0.0048 16.2 0.6 0.0099 15.1 0.2 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KLO06801.1 - 0.0063 15.9 0.4 0.01 15.2 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KLO06801.1 - 0.012 14.9 0.2 0.019 14.2 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KLO06801.1 - 0.012 14.7 0.9 0.024 13.7 0.9 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 KLO06801.1 - 0.015 14.8 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 KLO06801.1 - 0.019 14.0 0.7 0.049 12.7 0.7 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KLO06801.1 - 0.025 14.4 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 KLO06801.1 - 0.045 13.3 0.0 0.097 12.2 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase YbbR PF07949.12 KLO06801.1 - 0.14 12.6 0.1 0.38 11.1 0.1 1.7 1 0 0 1 1 1 0 YbbR-like protein Trp_halogenase PF04820.14 KLO06801.1 - 0.14 11.0 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase XdhC_C PF13478.6 KLO06801.1 - 0.16 12.4 0.0 1 9.8 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 KLO06801.1 - 0.18 12.3 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding F-box-like PF12937.7 KLO06803.1 - 7.4e-06 25.8 0.0 2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO06804.1 - 1.2e-05 25.1 0.1 3.5e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like Tet_JBP PF12851.7 KLO06807.1 - 8.2e-06 25.4 0.0 6.9e-05 22.3 0.0 1.9 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily BTB PF00651.31 KLO06811.1 - 0.0016 18.7 0.4 0.0033 17.6 0.4 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO06812.1 - 1.5e-06 28.4 0.1 6.5e-06 26.4 0.1 2.1 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO06813.1 - 8.1e-06 26.0 0.0 2.2e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO06814.1 - 1.9e-05 24.8 0.0 3.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 KLO06816.1 - 8.8e-40 136.7 38.8 2.4e-39 135.3 35.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KLO06816.1 - 6.5e-11 41.4 2.0 1.2e-10 40.5 2.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KLO06816.1 - 1.1e-10 41.0 18.1 7.4e-10 38.3 18.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KLO06816.1 - 8.8e-06 25.2 3.3 8.8e-06 25.2 3.3 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TMEMspv1-c74-12 PF11044.8 KLO06816.1 - 0.074 13.0 0.2 1.4 8.9 0.2 2.7 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein BTB PF00651.31 KLO06817.1 - 0.00054 20.2 0.0 0.0015 18.8 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO06818.1 - 0.00026 21.2 0.1 0.00083 19.6 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO06820.1 - 0.0014 18.9 0.3 0.0042 17.3 0.3 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO06821.1 - 0.00012 22.3 0.0 0.00038 20.6 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO06823.1 - 5.7e-05 23.3 0.1 0.00028 21.1 0.0 2.2 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO06824.1 - 0.00062 20.0 0.0 0.0025 18.0 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO06825.1 - 0.0027 17.9 0.1 0.0085 16.3 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain Transp_Tc5_C PF04236.15 KLO06826.1 - 0.29 11.5 2.4 0.39 11.1 0.0 2.3 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain p450 PF00067.22 KLO06827.1 - 4.4e-65 220.2 0.0 5.6e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Suf PF05843.14 KLO06827.1 - 0.21 11.6 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Complex1_LYR_2 PF13233.6 KLO06829.1 - 2.8e-21 76.1 0.0 4e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KLO06829.1 - 3.7e-12 46.1 0.0 8.3e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Cyanate_lyase PF02560.14 KLO06830.1 - 1.4e-32 111.3 0.0 2.1e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KLO06830.1 - 9.6e-05 22.7 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KLO06830.1 - 0.15 11.9 0.1 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KLO06830.1 - 0.16 11.7 0.0 7.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_3 PF01381.22 KLO06830.1 - 0.19 11.8 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix zf-C2H2 PF00096.26 KLO06831.1 - 0.027 14.9 2.9 1.5 9.5 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO06831.1 - 0.034 15.0 2.0 3.5 8.7 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 KLO06831.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger DUF3014 PF11219.8 KLO06832.1 - 0.051 13.8 0.0 0.075 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) Nucleoporin_FG PF13634.6 KLO06833.1 - 3.1e-05 24.7 11.9 3.1e-05 24.7 11.9 2.2 1 1 0 1 1 1 1 Nucleoporin FG repeat region Glyco_hydro_61 PF03443.14 KLO06834.1 - 8.8e-53 179.3 0.0 1.1e-52 179.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Herpes_gE PF02480.16 KLO06835.1 - 0.00051 18.9 0.0 0.00066 18.5 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Bacteriocin_IIc PF10439.9 KLO06835.1 - 0.03 14.4 1.0 0.045 13.9 1.0 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Ni_hydr_CYTB PF01292.20 KLO06835.1 - 0.045 13.4 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 BatA PF07584.11 KLO06835.1 - 0.1 12.9 0.5 0.29 11.5 0.4 1.8 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal LapA_dom PF06305.11 KLO06835.1 - 0.19 11.6 0.8 0.38 10.6 0.8 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CE2_N PF17996.1 KLO06836.1 - 0.0028 17.6 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal DUF1180 PF06679.12 KLO06836.1 - 0.011 16.1 0.4 0.029 14.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Il13Ra_Ig PF18001.1 KLO06836.1 - 0.054 13.6 0.2 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 Interleukin-13 receptor subunit alpha Ig-like domain WGG PF10273.9 KLO06837.1 - 3.8e-28 98.0 0.2 8.2e-28 96.9 0.0 1.6 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 KLO06837.1 - 0.12 12.5 0.2 0.12 12.5 0.2 1.8 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Phage_holin_2_1 PF04971.12 KLO06838.1 - 0.005 16.8 0.0 0.0093 16.0 0.0 1.5 1 1 0 1 1 1 1 Bacteriophage P21 holin S TMEM154 PF15102.6 KLO06838.1 - 0.015 15.2 0.3 0.022 14.7 0.3 1.3 1 0 0 1 1 1 0 TMEM154 protein family Cytomega_TRL10 PF06084.11 KLO06838.1 - 0.025 14.6 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein CE2_N PF17996.1 KLO06839.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal Shisa PF13908.6 KLO06839.1 - 0.046 14.0 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Alpha_GJ PF03229.13 KLO06839.1 - 0.075 13.6 0.0 0.34 11.5 0.0 1.9 2 0 0 2 2 2 0 Alphavirus glycoprotein J SKG6 PF08693.10 KLO06841.1 - 0.0029 17.0 1.9 0.0073 15.7 1.9 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KLO06841.1 - 0.018 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Insulin_TMD PF17870.1 KLO06841.1 - 0.064 13.3 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Stevor PF17410.2 KLO06841.1 - 0.07 12.7 0.4 0.13 11.8 0.2 1.6 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame stn_TNFRSF12A PF12191.8 KLO06841.1 - 0.12 12.6 0.9 11 6.3 0.2 2.5 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain RIFIN PF02009.16 KLO06841.1 - 0.25 11.2 0.0 0.38 10.6 0.0 1.2 1 0 0 1 1 1 0 Rifin Gram_pos_anchor PF00746.21 KLO06841.1 - 0.44 10.5 3.0 1.6 8.7 3.0 2.0 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TMEM154 PF15102.6 KLO06841.1 - 4.3 7.2 5.1 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 TMEM154 protein family Cellulase PF00150.18 KLO06842.1 - 7e-28 97.8 8.9 1e-27 97.3 8.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KLO06842.1 - 3.1e-12 46.2 11.4 9.7e-12 44.6 11.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KLO06842.1 - 0.00022 20.4 0.1 0.00063 19.0 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_44 PF12891.7 KLO06842.1 - 0.00088 19.3 0.1 0.00088 19.3 0.1 1.9 2 2 0 2 2 2 1 Glycoside hydrolase family 44 Glyco_hydro_42 PF02449.15 KLO06842.1 - 0.002 17.5 0.0 0.0045 16.4 0.0 1.6 1 1 0 1 1 1 1 Beta-galactosidase Tegument_dsDNA PF12818.7 KLO06842.1 - 0.19 10.8 0.6 0.4 9.8 0.6 1.6 1 1 0 1 1 1 0 dsDNA viral tegument protein MGC-24 PF05283.11 KLO06842.1 - 8.3 6.9 12.8 0.92 10.0 7.6 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SNARE_assoc PF09335.11 KLO06843.1 - 4e-18 66.0 7.1 4e-18 66.0 7.1 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein Yip1 PF04893.17 KLO06843.1 - 0.47 10.2 18.9 0.052 13.3 10.4 2.5 2 1 0 2 2 2 0 Yip1 domain FtsH_ext PF06480.15 KLO06843.1 - 1.3 9.5 4.4 17 5.8 0.1 2.9 2 0 0 2 2 2 0 FtsH Extracellular DUF4149 PF13664.6 KLO06843.1 - 1.4 9.3 6.8 15 6.0 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) DUF3671 PF12420.8 KLO06843.1 - 5.7 7.0 5.9 6.1 7.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF1349 PF07081.11 KLO06846.1 - 3.4e-29 101.8 0.1 4.7e-29 101.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) CRCB PF02537.15 KLO06848.1 - 0.11 12.8 4.2 0.23 11.8 4.2 1.5 1 1 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) Trp_oprn_chp PF09534.10 KLO06849.1 - 0.013 15.3 0.2 4.7 7.0 0.1 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1218 PF06749.12 KLO06849.1 - 0.065 13.8 0.6 0.43 11.1 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) FAM176 PF14851.6 KLO06849.1 - 0.14 11.8 4.5 1.4 8.6 0.1 2.6 2 1 0 2 2 2 0 FAM176 family SARAF PF06682.12 KLO06849.1 - 0.19 11.4 7.0 1.4 8.5 7.0 2.0 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 KLO06849.1 - 0.63 11.0 6.3 1.7 9.7 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Zip PF02535.22 KLO06849.1 - 9 5.4 9.2 39 3.3 9.2 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter DUF4536 PF15055.6 KLO06850.1 - 2.6e-05 24.4 2.5 4.5e-05 23.6 2.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) Plasmid_stab_B PF10784.9 KLO06850.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Plasmid stability protein WD40 PF00400.32 KLO06852.1 - 9.4e-144 463.0 51.0 1.3e-09 38.5 0.1 14.8 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO06852.1 - 1.1e-41 141.0 8.6 0.1 12.9 0.0 14.2 1 1 13 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO06852.1 - 6.6e-19 68.5 0.0 0.0067 16.3 0.0 6.2 1 1 5 8 8 8 7 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KLO06852.1 - 3.5e-16 59.0 1.2 1.3 7.6 0.0 12.8 10 2 3 14 14 14 1 Nucleoporin Nup120/160 PD40 PF07676.12 KLO06852.1 - 5.9e-16 57.9 0.0 6.1 6.9 0.0 12.4 14 0 0 14 14 14 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KLO06852.1 - 4.5e-13 49.2 0.0 9 5.5 0.0 10.5 7 5 4 11 11 11 0 WD40-like domain Ge1_WD40 PF16529.5 KLO06852.1 - 3.1e-08 33.0 1.1 42 2.9 0.0 10.8 4 2 4 13 13 13 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_S9_N PF02897.15 KLO06852.1 - 3.3e-06 26.2 0.1 2.3 6.9 0.0 6.1 2 2 5 7 7 7 1 Prolyl oligopeptidase, N-terminal beta-propeller domain NACHT PF05729.12 KLO06852.1 - 7.6e-06 25.9 0.0 2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain SdiA-regulated PF06977.11 KLO06852.1 - 1.1e-05 24.8 0.0 1.5 8.0 0.0 5.0 1 1 4 6 6 6 1 SdiA-regulated DsbC_N PF10411.9 KLO06852.1 - 2.7e-05 23.5 5.8 1.3e+02 2.1 0.0 10.4 12 0 0 12 12 12 0 Disulfide bond isomerase protein N-terminus DUF5018 PF16410.5 KLO06852.1 - 0.0019 17.0 0.2 1.4 7.6 0.0 3.8 2 1 2 4 4 4 1 Domain of unknown function (DUF5018) NAGPA PF09992.9 KLO06852.1 - 0.002 18.4 4.0 48 4.1 0.1 7.3 2 2 3 5 5 5 0 Phosphodiester glycosidase AAA_16 PF13191.6 KLO06852.1 - 0.0041 17.5 0.0 0.02 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KLO06852.1 - 0.019 14.9 0.0 0.064 13.2 0.0 1.9 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KLO06852.1 - 0.048 14.2 0.1 0.13 12.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 KLO06852.1 - 0.053 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KLO06852.1 - 0.074 12.8 0.1 0.27 11.0 0.1 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KLO06852.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 KLO06852.1 - 0.17 11.7 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase nos_propeller PF18764.1 KLO06852.1 - 8.4 6.4 28.1 45 4.0 0.0 10.5 14 0 0 14 14 12 0 Nitrous oxide reductase propeller repeat DDE_Tnp_4 PF13359.6 KLO06853.1 - 3e-20 72.5 0.0 4.2e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TTKRSYEDQ PF10212.9 KLO06854.1 - 0.0012 17.9 1.6 0.0018 17.4 1.6 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein DUF641 PF04859.12 KLO06854.1 - 0.0094 16.3 2.1 0.024 15.0 2.1 1.7 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Myb_DNA-binding PF00249.31 KLO06854.1 - 0.017 15.3 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain ATG16 PF08614.11 KLO06854.1 - 0.11 12.8 17.3 0.54 10.4 7.2 2.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Lipase_chap PF03280.14 KLO06854.1 - 0.5 10.3 12.6 0.3 11.0 8.6 2.5 3 0 0 3 3 3 0 Proteobacterial lipase chaperone protein Phospho_p8 PF10195.9 KLO06854.1 - 5.7 7.5 10.2 0.16 12.5 2.1 2.7 2 0 0 2 2 2 0 DNA-binding nuclear phosphoprotein p8 Med21 PF11221.8 KLO06854.1 - 6.8 6.9 10.9 0.72 10.1 4.1 2.7 3 1 0 3 3 3 0 Subunit 21 of Mediator complex WW PF00397.26 KLO06856.1 - 8.1e-13 48.2 8.1 1.5e-06 28.2 3.9 2.4 2 0 0 2 2 2 2 WW domain MyTH4 PF00784.17 KLO06857.1 - 5.9e-30 103.9 0.0 1.2e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 MyTH4 domain RhoGAP PF00620.27 KLO06857.1 - 4e-27 94.9 0.0 7.1e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain DUF4085 PF13315.6 KLO06858.1 - 0.28 10.8 2.9 4.8 6.8 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4085) CBFD_NFYB_HMF PF00808.23 KLO06858.1 - 0.59 10.5 6.1 3.6 7.9 0.2 3.1 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-C2H2_3 PF13878.6 KLO06858.1 - 0.84 9.5 3.0 14 5.6 0.3 2.5 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Pkinase_Tyr PF07714.17 KLO06861.1 - 1.1e-42 146.1 0.0 1.6e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO06861.1 - 3.5e-37 128.2 0.0 5.5e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KLO06861.1 - 9.3e-05 21.4 0.3 0.00013 20.9 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO06861.1 - 0.0033 17.4 0.1 0.007 16.3 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO06861.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KLO06861.1 - 0.067 12.8 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 RIO1 family DUF3864 PF12980.7 KLO06861.1 - 0.071 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) EPO_TPO PF00758.18 KLO06862.1 - 0.016 15.2 2.3 0.86 9.6 0.1 2.3 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin MNE1 PF13762.6 KLO06862.1 - 0.044 13.8 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component MerR-DNA-bind PF09278.11 KLO06862.1 - 0.072 13.6 0.1 1.6 9.3 0.1 2.4 2 0 0 2 2 2 0 MerR, DNA binding DUF3103 PF11301.8 KLO06862.1 - 0.28 9.9 4.4 0.14 11.0 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3103) FlgN PF05130.12 KLO06862.1 - 1.7 9.2 7.1 5.7 7.4 6.6 2.1 1 1 1 2 2 2 0 FlgN protein TolA_bind_tri PF16331.5 KLO06862.1 - 2.3 8.4 6.7 0.64 10.1 1.2 2.6 2 1 1 3 3 3 0 TolA binding protein trimerisation Peptidase_C12 PF01088.21 KLO06863.1 - 1.2e-55 188.6 0.0 1.7e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KLO06863.1 - 2.9e-14 52.7 0.1 6e-14 51.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Med31 PF05669.12 KLO06864.1 - 1e-36 124.8 5.8 1.3e-36 124.4 5.8 1.1 1 0 0 1 1 1 1 SOH1 Nod_GRP PF07806.11 KLO06864.1 - 0.0019 18.0 3.7 0.0097 15.7 0.1 2.4 2 0 0 2 2 2 1 Nodule-specific GRP repeat Spt5-NGN PF03439.13 KLO06865.1 - 4.3e-07 29.7 0.0 9.3e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KLO06865.1 - 0.00046 21.1 6.6 0.0017 19.3 6.6 2.0 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KLO06865.1 - 0.0083 16.1 25.9 1.1 9.3 0.3 5.8 5 0 0 5 5 5 3 KOW motif DUF3912 PF13051.6 KLO06865.1 - 0.01 16.1 5.5 0.39 11.0 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3912) SH3_13 PF18335.1 KLO06865.1 - 0.056 13.3 0.1 0.35 10.7 0.1 2.3 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain K_channel_TID PF07941.11 KLO06865.1 - 0.11 13.0 1.2 0.3 11.6 1.2 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain zf-MYND PF01753.18 KLO06866.1 - 2.9e-09 36.8 10.9 7.3e-09 35.6 10.9 1.7 1 0 0 1 1 1 1 MYND finger NapD PF03927.13 KLO06866.1 - 0.021 14.9 0.1 0.045 13.8 0.1 1.5 1 0 0 1 1 1 0 NapD protein CdvA PF18822.1 KLO06866.1 - 0.069 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 CdvA-like coiled-coil domain UPF0242 PF06785.11 KLO06866.1 - 0.081 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RasGEF_N_2 PF14663.6 KLO06866.1 - 0.37 11.2 1.5 0.61 10.5 0.4 2.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain zf-C6H2 PF15801.5 KLO06866.1 - 4.8 7.6 16.3 1.8 9.0 11.2 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KLO06867.1 - 4.3e-09 36.3 10.4 8.1e-09 35.4 10.4 1.4 1 0 0 1 1 1 1 MYND finger CDC45 PF02724.14 KLO06867.1 - 0.67 8.2 4.9 0.96 7.7 4.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Clp_N PF02861.20 KLO06867.1 - 1.9 8.7 5.0 42 4.4 0.0 3.3 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component adh_short_C2 PF13561.6 KLO06868.1 - 4.2e-26 92.0 0.1 6.3e-26 91.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO06868.1 - 2.6e-22 79.2 0.1 5.2e-22 78.3 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Phage_tail_T PF06223.12 KLO06868.1 - 0.15 12.6 1.9 1.3 9.6 0.0 2.6 2 1 1 3 3 3 0 Minor tail protein T HgmA PF04209.13 KLO06869.1 - 4.1e-176 585.9 0.2 4.8e-176 585.6 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase zf-MYND PF01753.18 KLO06870.1 - 3.8e-08 33.3 14.6 7.7e-08 32.3 14.6 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 KLO06870.1 - 0.0039 18.4 0.9 0.0068 17.6 0.9 1.3 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-Mss51 PF13824.6 KLO06870.1 - 3.6 7.8 7.6 1.9 8.6 4.3 2.3 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 ketoacyl-synt PF00109.26 KLO06872.1 - 1.4e-67 228.0 0.3 2.7e-67 227.0 0.3 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KLO06872.1 - 5.9e-44 150.9 0.0 1.6e-43 149.4 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KLO06872.1 - 3.6e-36 123.8 0.4 7e-36 122.8 0.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KLO06872.1 - 1.4e-26 93.5 0.0 2.1e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KLO06872.1 - 4e-23 81.5 3.5 9.6e-11 41.9 0.2 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site SAT PF16073.5 KLO06872.1 - 1.9e-15 57.2 1.2 6.9e-15 55.4 0.1 2.3 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thioesterase PF00975.20 KLO06872.1 - 7e-13 49.2 0.0 3.9e-12 46.8 0.0 2.4 1 1 0 1 1 1 1 Thioesterase domain Thiolase_N PF00108.23 KLO06872.1 - 5.5e-07 29.2 0.2 2.1e-06 27.3 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 KLO06872.1 - 5.8e-05 23.8 1.1 0.0024 18.5 0.0 3.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 KLO06872.1 - 8.9e-05 22.9 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_3 PF07859.13 KLO06872.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Zn_clus PF00172.18 KLO06876.1 - 0.00062 19.8 8.3 0.0011 19.1 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1192 PF06698.11 KLO06877.1 - 0.1 12.6 0.2 0.28 11.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) CTK3_C PF12350.8 KLO06878.1 - 2.5e-25 88.4 6.0 4.9e-25 87.5 6.0 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.8 KLO06878.1 - 2e-23 82.7 0.0 2.8e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 UbiA PF01040.18 KLO06879.1 - 1e-17 64.3 15.8 1.4e-17 63.9 15.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family PfkB PF00294.24 KLO06880.1 - 8.4e-12 45.0 0.0 1.1e-07 31.5 0.0 3.1 3 1 0 3 3 3 2 pfkB family carbohydrate kinase BTB PF00651.31 KLO06881.1 - 0.00023 21.4 0.0 0.00056 20.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BAR_3 PF16746.5 KLO06882.1 - 0.033 13.9 0.3 0.071 12.8 0.3 1.5 1 0 0 1 1 1 0 BAR domain of APPL family HDOD PF08668.12 KLO06885.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.3 1 1 0 1 1 1 0 HDOD domain TUG-UBL1 PF11470.8 KLO06886.1 - 0.0005 20.2 0.0 0.0012 19.1 0.0 1.6 1 1 0 1 1 1 1 TUG ubiquitin-like domain PsbI PF02532.14 KLO06887.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Ad_Cy_reg PF16701.5 KLO06889.1 - 0.048 13.4 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain Antimicrobial_1 PF08018.11 KLO06889.1 - 0.18 11.9 0.2 0.34 11.1 0.2 1.4 1 0 0 1 1 1 0 Frog antimicrobial peptide Imm3 PF14425.6 KLO06890.1 - 0.087 12.9 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Immunity protein Imm3 LBR_tudor PF09465.10 KLO06892.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF1129 PF06570.11 KLO06892.1 - 0.22 11.0 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) WD40 PF00400.32 KLO06892.1 - 1 10.3 6.3 0.99 10.4 0.3 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat YiaAB PF05360.14 KLO06892.1 - 1.2 9.4 4.2 2.8 8.2 0.6 2.3 2 0 0 2 2 2 0 yiaA/B two helix domain ABC_export PF16962.5 KLO06892.1 - 2 6.7 4.4 2.8 6.3 4.4 1.1 1 0 0 1 1 1 0 Putative ABC exporter Polyoma_lg_T_C PF06431.11 KLO06900.1 - 0.14 11.0 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus G6PD_C PF02781.16 KLO06901.1 - 1.2e-112 375.9 0.0 2.4e-112 374.9 0.0 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KLO06901.1 - 2.3e-60 204.3 0.1 4.1e-60 203.4 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain IPK PF03770.16 KLO06901.1 - 0.051 13.4 0.2 0.89 9.4 0.1 2.1 2 0 0 2 2 2 0 Inositol polyphosphate kinase LON_substr_bdg PF02190.16 KLO06902.1 - 4.1e-21 75.8 0.0 6.3e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KLO06902.1 - 8.4e-12 44.7 11.8 8.4e-12 44.7 11.8 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO06902.1 - 8.2e-08 32.2 17.8 5e-06 26.4 10.2 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KLO06902.1 - 3.7e-07 30.2 18.9 0.00015 21.8 10.8 2.9 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KLO06902.1 - 4.2e-07 29.7 8.6 4.2e-07 29.7 8.6 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO06902.1 - 2.2e-06 27.9 11.8 2.2e-06 27.9 11.8 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KLO06902.1 - 5.5e-06 26.2 10.4 5.5e-06 26.2 10.4 2.9 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4 PF00097.25 KLO06902.1 - 5.5e-06 26.1 19.4 7.8e-06 25.7 11.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KLO06902.1 - 0.00012 22.1 12.9 0.00013 22.0 4.1 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KLO06902.1 - 0.00019 21.2 9.4 0.00019 21.2 9.4 2.7 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KLO06902.1 - 0.00099 18.9 1.6 0.0023 17.7 1.6 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KLO06902.1 - 0.0012 18.6 3.1 0.0012 18.6 3.1 2.6 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KLO06902.1 - 0.0066 16.7 7.5 0.0066 16.7 7.5 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-P11 PF03854.14 KLO06902.1 - 0.27 10.9 8.3 0.74 9.5 8.3 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-ANAPC11 PF12861.7 KLO06902.1 - 0.69 10.0 5.6 0.31 11.1 2.6 2.0 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DDE_1 PF03184.19 KLO06903.1 - 1.8e-10 40.8 0.0 4e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO06903.1 - 0.0033 17.2 0.0 0.0075 16.0 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF1682 PF07946.14 KLO06905.1 - 1.1e-91 307.5 1.2 1.2e-91 307.3 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF3818 PF12825.7 KLO06907.1 - 1.3e-130 435.3 0.2 2.4e-130 434.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KLO06907.1 - 1.8e-31 108.8 1.9 3.7e-31 107.8 1.9 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KLO06907.1 - 1.8e-10 40.8 0.0 5.4e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 PX domain Hormone_1 PF00103.20 KLO06907.1 - 0.089 12.5 0.2 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Somatotropin hormone family GREB1 PF15782.5 KLO06907.1 - 1.4 5.9 7.6 2.2 5.3 7.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase PF00069.25 KLO06908.1 - 6.1e-65 219.2 0.3 1.4e-43 149.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO06908.1 - 1.9e-28 99.5 0.2 1.9e-21 76.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KLO06908.1 - 1.3e-07 30.9 0.2 2e-07 30.3 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KLO06908.1 - 9.4e-05 21.9 0.4 0.00094 18.6 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO06908.1 - 0.00012 22.1 0.2 0.023 14.6 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO06908.1 - 0.0023 17.3 0.3 0.014 14.8 0.1 2.5 2 1 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 KLO06908.1 - 0.011 16.4 0.2 0.038 14.7 0.2 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain RIO1 PF01163.22 KLO06908.1 - 0.044 13.4 1.3 0.072 12.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 KLO06908.1 - 0.057 12.5 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 KLO06908.1 - 0.064 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TFIIA PF03153.13 KLO06908.1 - 0.25 11.3 10.3 0.39 10.6 10.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase_fungal PF17667.1 KLO06908.1 - 0.76 8.5 5.6 2.1 7.1 5.6 1.9 1 1 0 1 1 1 0 Fungal protein kinase DUF4834 PF16118.5 KLO06908.1 - 1.4 9.9 5.4 4.1 8.4 4.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2967 PF11179.8 KLO06908.1 - 5.4 5.0 7.9 7.5 4.5 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Mid1 PF12929.7 KLO06909.1 - 4.3e-54 184.3 0.0 5.8e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KLO06909.1 - 0.0058 17.2 2.4 0.35 11.5 0.2 2.4 2 0 0 2 2 2 2 Fz domain GST_N_2 PF13409.6 KLO06910.1 - 2e-11 44.0 0.0 3.5e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KLO06910.1 - 2.3e-11 43.9 0.0 4.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KLO06910.1 - 0.016 15.5 0.0 0.07 13.5 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KLO06910.1 - 0.017 15.3 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KLO06910.1 - 0.043 14.6 0.0 0.079 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KLO06910.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HLH PF00010.26 KLO06914.1 - 0.00054 19.9 0.9 0.00054 19.9 0.9 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2890 PF11081.8 KLO06914.1 - 0.13 12.4 4.4 0.16 12.1 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TPR_1 PF00515.28 KLO06917.1 - 2.7e-06 26.9 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO06917.1 - 2.8e-05 23.9 4.7 0.034 14.3 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat UBA PF00627.31 KLO06917.1 - 9.3e-05 22.3 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain TPR_12 PF13424.6 KLO06917.1 - 0.018 15.3 5.4 6.4 7.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KLO06917.1 - 0.02 15.5 0.0 0.02 15.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KLO06917.1 - 0.097 12.7 0.0 1.9 8.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 KLO06917.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain DUF4449 PF14613.6 KLO06922.1 - 3.5e-34 118.3 0.1 3.5e-34 118.3 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) FLgD_tudor PF13861.6 KLO06923.1 - 0.12 12.6 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 FlgD Tudor-like domain Lipoprotein_7 PF01540.16 KLO06924.1 - 0.00021 20.7 0.3 0.00034 20.0 0.3 1.3 1 0 0 1 1 1 1 Adhesin lipoprotein DUF2959 PF11172.8 KLO06924.1 - 0.019 15.1 0.3 0.67 10.1 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2959) ColG_sub PF18496.1 KLO06924.1 - 0.057 13.6 0.0 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 Collagenase G catalytic helper subdomain ALIX_LYPXL_bnd PF13949.6 KLO06924.1 - 0.061 12.6 0.0 0.15 11.3 0.0 1.7 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV DASH_Dad2 PF08654.10 KLO06924.1 - 0.067 13.6 0.1 0.98 9.9 0.0 2.9 2 1 0 3 3 3 0 DASH complex subunit Dad2 Lipase_3 PF01764.25 KLO06925.1 - 1.1e-19 70.7 0.0 1.9e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Emaravirus_P4 PF16505.5 KLO06925.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily HTH_38 PF13936.6 KLO06925.1 - 0.18 11.6 0.1 0.5 10.2 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Alpha-amylase PF00128.24 KLO06926.1 - 3.1e-122 408.4 0.2 4.7e-122 407.8 0.2 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KLO06926.1 - 2.8e-08 33.7 0.0 7e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KLO06926.1 - 0.0064 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain CSTF_C PF14304.6 KLO06927.1 - 4.2e-07 29.4 7.6 4e-06 26.3 2.3 3.1 2 1 1 3 3 3 2 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 KLO06927.1 - 0.00023 21.5 4.5 0.00023 21.5 4.5 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 WXG100 PF06013.12 KLO06929.1 - 3.7e-06 27.1 1.6 0.0041 17.3 0.1 3.3 3 0 0 3 3 3 1 Proteins of 100 residues with WXG Apolipoprotein PF01442.18 KLO06929.1 - 1.5e-05 25.0 0.7 0.076 12.9 0.0 2.5 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain Rsd_AlgQ PF04353.13 KLO06929.1 - 0.0018 18.2 0.6 0.005 16.8 0.2 2.0 2 1 0 2 2 2 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ FlaC_arch PF05377.11 KLO06929.1 - 0.049 14.0 0.9 20 5.6 0.0 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) SKA2 PF16740.5 KLO06929.1 - 0.054 13.3 0.3 0.38 10.6 0.0 2.4 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Glyco_H_20C_C PF18088.1 KLO06929.1 - 0.058 13.2 0.1 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Glycoside Hydrolase 20C C-terminal domain Baculo_PEP_C PF04513.12 KLO06929.1 - 0.071 13.1 0.0 13 5.8 0.0 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5344 PF17279.2 KLO06929.1 - 0.11 13.1 3.1 4.5 7.9 0.1 3.6 3 1 1 4 4 4 0 Family of unknown function (DUF5344) CCDC-167 PF15188.6 KLO06929.1 - 6.5 7.2 10.1 7.3 7.0 0.2 3.4 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 Apolipoprotein PF01442.18 KLO06930.1 - 0.00011 22.1 0.1 0.00019 21.4 0.1 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Prominin PF05478.11 KLO06930.1 - 0.022 12.8 0.5 0.025 12.6 0.5 1.1 1 0 0 1 1 1 0 Prominin Scaffolding_pro PF11418.8 KLO06930.1 - 0.072 13.7 0.2 0.28 11.8 0.1 2.0 3 0 0 3 3 3 0 Phi29 scaffolding protein Nup54 PF13874.6 KLO06930.1 - 0.075 13.1 0.1 0.15 12.2 0.1 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF2706 PF10913.8 KLO06937.1 - 0.12 12.2 3.0 0.22 11.4 0.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2706) DUF2569 PF10754.9 KLO06941.1 - 7.7 7.0 15.0 0.078 13.4 4.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) Peptidase_C39_2 PF13529.6 KLO06943.1 - 0.036 14.6 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Peptidase_C39 like family HydF_dimer PF18128.1 KLO06943.1 - 0.13 12.4 0.0 2.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Hydrogen maturase F dimerization domain Glyco_hydro_92 PF07971.12 KLO06944.1 - 2.4e-150 501.5 6.3 2.9e-150 501.2 6.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KLO06944.1 - 2e-60 204.7 3.7 4e-60 203.7 3.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Spp-24 PF07448.11 KLO06947.1 - 0.025 14.8 0.1 1.5 9.1 0.1 2.3 2 0 0 2 2 2 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Fungal_trans PF04082.18 KLO06950.1 - 5.7e-22 78.0 0.0 9.6e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO06950.1 - 2.1e-10 40.6 11.2 5.6e-10 39.2 11.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DASH_Ask1 PF08655.10 KLO06952.1 - 0.19 11.6 0.0 0.7 9.8 0.0 1.8 2 0 0 2 2 2 0 DASH complex subunit Ask1 F-box-like PF12937.7 KLO06956.1 - 3e-08 33.4 7.6 2.1e-07 30.7 1.2 3.4 3 0 0 3 3 3 2 F-box-like XRN_M PF17846.1 KLO06956.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain RRM_1 PF00076.22 KLO06957.1 - 4.3e-51 170.6 0.4 4.3e-18 64.9 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KLO06957.1 - 9.4e-13 47.8 0.0 7.1e-05 22.6 0.0 4.6 4 1 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KLO06957.1 - 1.1e-05 25.4 0.0 0.02 14.9 0.0 3.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KLO06957.1 - 0.00017 21.7 0.1 1 9.5 0.0 4.1 4 0 0 4 4 4 1 RNA recognition motif Nup35_RRM PF05172.13 KLO06957.1 - 0.0011 18.9 0.0 0.4 10.7 0.0 2.8 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KLO06957.1 - 0.011 15.4 0.0 0.042 13.4 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.13 KLO06957.1 - 0.029 15.0 1.0 0.29 11.8 0.0 2.9 2 1 0 2 2 2 0 Nmi/IFP 35 domain (NID) RRM_3 PF08777.11 KLO06957.1 - 0.13 12.3 2.5 1.5 8.9 0.1 3.6 3 0 0 3 3 3 0 RNA binding motif DUF3664 PF12406.8 KLO06957.1 - 0.76 10.4 3.5 1.8 9.2 3.5 1.6 1 0 0 1 1 1 0 Surface protein CSN5_C PF18323.1 KLO06957.1 - 1.1 10.3 5.2 32 5.5 4.8 3.2 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Zein-binding PF04576.15 KLO06957.1 - 1.9 8.8 8.7 4.5 7.6 4.7 2.8 1 1 1 2 2 2 0 Zein-binding TPR_14 PF13428.6 KLO06957.1 - 3.8 8.6 5.1 9.7 7.3 0.1 3.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Peptidase_M16 PF00675.20 KLO06958.1 - 3.7e-52 176.3 1.4 6.9e-52 175.4 0.4 2.0 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KLO06958.1 - 2.5e-39 135.2 0.0 3.3e-37 128.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_U40 PF10464.9 KLO06958.1 - 0.0093 15.7 0.1 0.033 13.9 0.0 1.9 2 1 0 2 2 2 1 Peptidase U40 MTD PF01993.18 KLO06958.1 - 0.034 13.5 0.0 3.7 6.8 0.0 2.2 1 1 1 2 2 2 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase ETF PF01012.21 KLO06959.1 - 1e-41 142.8 2.0 1.3e-41 142.5 2.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Synthase_beta PF11421.8 KLO06961.1 - 0.047 14.4 1.5 0.58 10.9 0.4 2.4 2 0 0 2 2 2 0 ATP synthase F1 beta subunit Helicase_C_2 PF13307.6 KLO06962.1 - 2.5e-54 184.0 0.1 8.2e-54 182.3 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 KLO06962.1 - 4.8e-36 124.0 0.0 1.8e-35 122.2 0.0 2.0 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KLO06962.1 - 0.00027 21.0 0.3 0.2 11.6 0.0 2.9 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 KLO06962.1 - 0.0014 18.4 0.0 0.063 13.0 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase T2SSE PF00437.20 KLO06962.1 - 0.014 14.5 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 KLO06962.1 - 0.015 15.6 0.1 12 6.2 0.1 3.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KLO06962.1 - 0.023 14.2 0.4 0.061 12.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KLO06962.1 - 0.04 13.4 0.0 0.54 9.7 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 KLO06962.1 - 0.081 12.6 0.0 1 9.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KLO06962.1 - 6.3 6.5 7.7 14 5.4 4.4 2.6 2 1 0 2 2 2 0 AAA domain Ribosomal_L23eN PF03939.13 KLO06963.1 - 1.9e-18 66.4 8.8 5.4e-18 64.9 8.8 1.8 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KLO06963.1 - 2.4e-14 53.4 0.9 2.4e-14 53.4 0.9 2.7 2 1 0 2 2 2 1 Ribosomal protein L23 ASL_C PF08328.11 KLO06963.1 - 0.00047 20.2 0.2 0.0012 18.9 0.1 1.7 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal DUF5451 PF17532.2 KLO06963.1 - 0.022 15.1 1.0 0.033 14.5 1.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5451) YihI PF04220.12 KLO06963.1 - 0.05 13.3 1.7 0.067 12.9 1.7 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) Pneumo_att_G PF05539.11 KLO06963.1 - 0.3 10.6 3.5 0.32 10.5 3.5 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Nipped-B_C PF12830.7 KLO06964.1 - 4e-51 173.7 0.4 4.8e-50 170.1 0.7 2.7 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KLO06964.1 - 7.2e-13 48.6 11.0 1.2e-12 47.9 2.7 3.9 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KLO06964.1 - 4.1e-05 23.5 1.7 0.44 10.9 0.0 4.9 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 KLO06964.1 - 0.00019 21.5 0.2 0.0016 18.5 0.1 2.7 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KLO06964.1 - 0.00022 21.6 0.3 0.0071 16.7 0.0 4.1 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KLO06964.1 - 0.03 14.9 4.8 42 4.8 0.0 5.0 4 0 0 4 4 4 0 HEAT-like repeat M11L PF11099.8 KLO06964.1 - 0.14 12.4 0.3 14 5.9 0.0 2.8 2 0 0 2 2 2 0 Apoptosis regulator M11L like PMC2NT PF08066.12 KLO06964.1 - 2.9 8.7 5.7 7.9 7.2 0.3 4.2 3 1 0 3 3 3 0 PMC2NT (NUC016) domain Hpt PF01627.23 KLO06965.1 - 1.1e-10 41.6 0.3 1.5e-10 41.1 0.3 1.2 1 0 0 1 1 1 1 Hpt domain EHN PF06441.12 KLO06966.1 - 3.3e-34 117.5 1.1 1e-33 115.9 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KLO06966.1 - 9.2e-10 38.6 0.1 1.4e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO06966.1 - 2.8e-06 28.1 1.4 6.2e-06 27.0 1.4 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family OCD_Mu_crystall PF02423.15 KLO06967.1 - 8.1e-35 120.3 3.0 1.4e-33 116.2 2.7 2.4 1 1 1 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KLO06967.1 - 0.00044 20.3 0.0 0.015 15.4 0.0 2.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Transket_pyr PF02779.24 KLO06968.1 - 1.4e-65 220.3 0.0 2.1e-65 219.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KLO06968.1 - 1.4e-61 208.1 0.0 2e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KLO06968.1 - 7.4e-53 178.3 0.0 1.3e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KLO06968.1 - 2.2e-19 68.8 0.4 4.5e-19 67.8 0.4 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus TPR_17 PF13431.6 KLO06968.1 - 0.081 13.3 0.0 0.28 11.6 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat CoA_transf_3 PF02515.17 KLO06969.1 - 9.2e-125 416.6 0.0 1e-124 416.4 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Wzz PF02706.15 KLO06970.1 - 0.3 11.4 1.6 1.1 9.6 1.6 2.0 1 0 0 1 1 1 0 Chain length determinant protein Peptidase_S9 PF00326.21 KLO06971.1 - 1.3e-43 148.9 0.0 1.9e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KLO06971.1 - 1.1e-10 41.4 0.1 3.5e-10 39.8 0.1 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KLO06971.1 - 1.3e-07 31.7 0.1 0.019 14.8 0.1 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KLO06971.1 - 1.4e-06 27.7 0.2 0.0031 16.8 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KLO06971.1 - 0.00013 22.0 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 KLO06971.1 - 0.00013 21.7 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 KLO06971.1 - 0.00021 21.2 0.3 0.0021 17.9 0.3 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KLO06971.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PD40 PF07676.12 KLO06971.1 - 0.0061 16.5 0.3 0.018 15.0 0.3 1.8 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KLO06971.1 - 0.0065 15.3 0.1 1.6 7.4 0.0 2.1 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_6 PF12697.7 KLO06971.1 - 0.016 15.8 1.0 0.15 12.7 1.0 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 KLO06971.1 - 0.031 13.9 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PAF-AH_p_II PF03403.13 KLO06971.1 - 0.12 10.8 0.0 0.23 10.0 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II RRM_1 PF00076.22 KLO06972.1 - 3.3e-10 39.7 0.0 8e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KLO06972.1 - 3.7e-06 27.2 0.1 9.9e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 PWI domain Methyltransf_25 PF13649.6 KLO06976.1 - 2.7e-13 50.4 0.0 6.9e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO06976.1 - 3.2e-11 43.3 0.0 6.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO06976.1 - 4.1e-11 43.4 0.1 2.6e-10 40.8 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain PrmA PF06325.13 KLO06976.1 - 9.3e-11 41.6 0.3 1.9e-10 40.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KLO06976.1 - 1.1e-07 31.8 0.0 3.2e-06 27.1 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KLO06976.1 - 1.7e-06 27.7 0.1 3.1e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KLO06976.1 - 1.4e-05 25.0 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KLO06976.1 - 5e-05 22.4 0.0 7.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 KLO06976.1 - 0.00011 22.8 0.0 0.0003 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KLO06976.1 - 0.00049 19.9 0.0 0.00095 19.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.20 KLO06976.1 - 0.0007 19.0 0.0 0.0017 17.7 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 KLO06976.1 - 0.0012 18.5 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 KLO06976.1 - 0.003 17.4 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 KLO06976.1 - 0.004 16.6 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KLO06976.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KLO06976.1 - 0.024 15.6 0.0 0.077 14.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 KLO06976.1 - 0.036 13.9 0.0 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase UPF0020 PF01170.18 KLO06976.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF3915 PF13054.6 KLO06978.1 - 0.71 9.9 1.8 0.97 9.4 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DIOX_N PF14226.6 KLO06979.1 - 3.3e-33 114.9 0.0 5.4e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO06979.1 - 3.6e-20 72.3 0.0 6.5e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily XPG_I_2 PF12813.7 KLO06980.1 - 1.3e-05 24.9 0.0 4.6e-05 23.0 0.0 2.0 3 0 0 3 3 3 1 XPG domain containing XPG_N PF00752.17 KLO06980.1 - 0.00045 20.6 0.0 0.0012 19.3 0.0 1.7 1 1 0 1 1 1 1 XPG N-terminal domain Sigma70_ner PF04546.13 KLO06980.1 - 7 6.5 9.5 16 5.3 9.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Aldo_ket_red PF00248.21 KLO06981.1 - 6.5e-49 166.7 0.2 4.4e-48 164.0 0.2 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family CsbD PF05532.12 KLO06983.1 - 0.001 19.0 1.7 0.0028 17.5 1.7 1.8 1 0 0 1 1 1 1 CsbD-like CsbD PF05532.12 KLO06984.1 - 2.7e-06 27.2 1.3 4.6e-06 26.4 0.3 1.9 2 0 0 2 2 2 1 CsbD-like TPR_12 PF13424.6 KLO06984.1 - 0.02 15.2 0.6 0.066 13.5 0.2 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat AAA PF00004.29 KLO06985.1 - 5.6e-41 140.1 0.0 1.2e-40 139.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KLO06985.1 - 3e-18 65.5 0.0 6e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KLO06985.1 - 1.4e-10 40.8 0.2 3.4e-10 39.6 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KLO06985.1 - 0.00012 22.5 0.1 0.031 14.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KLO06985.1 - 0.00025 20.8 0.0 0.00062 19.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KLO06985.1 - 0.0003 20.8 0.2 0.0056 16.7 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KLO06985.1 - 0.0006 20.0 0.7 0.0044 17.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 KLO06985.1 - 0.0017 17.8 0.0 0.039 13.4 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 KLO06985.1 - 0.0026 18.0 0.4 0.16 12.3 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KLO06985.1 - 0.0088 16.2 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KLO06985.1 - 0.01 15.2 0.1 0.035 13.5 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KLO06985.1 - 0.019 14.8 0.7 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF1192 PF06698.11 KLO06985.1 - 0.025 14.6 0.2 0.067 13.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF815 PF05673.13 KLO06985.1 - 0.042 13.0 0.0 0.089 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KLO06985.1 - 0.059 13.1 0.3 0.17 11.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KLO06985.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KLO06985.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 KLO06985.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Cyclin_N PF00134.23 KLO06986.1 - 1.6e-09 37.6 0.1 1.1e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KLO06986.1 - 0.00089 19.3 0.3 0.011 15.8 0.1 2.5 2 1 0 2 2 2 1 Cyclin, C-terminal domain MBOAT_2 PF13813.6 KLO06987.1 - 7.9e-16 58.1 0.6 7.9e-16 58.1 0.6 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Glyco_trans_4_4 PF13579.6 KLO06988.1 - 0.0012 19.3 1.8 0.0016 18.9 1.8 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF5566 PF17721.1 KLO06988.1 - 0.15 12.3 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5566) Curto_V3 PF07436.11 KLO06990.1 - 0.037 14.4 0.0 0.073 13.5 0.0 1.4 1 0 0 1 1 1 0 Curtovirus V3 protein Glyco_hydro_61 PF03443.14 KLO06991.1 - 5.8e-62 209.3 0.1 1.1e-61 208.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KLO06991.1 - 5.2e-10 39.1 14.6 1.3e-09 37.8 14.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF5008 PF16400.5 KLO06991.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5008) PWI PF01480.17 KLO06992.1 - 3.2e-28 97.9 0.1 5.4e-28 97.1 0.1 1.4 1 0 0 1 1 1 1 PWI domain EMP24_GP25L PF01105.24 KLO06993.1 - 1.2e-39 136.1 0.0 1.4e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Trimer_CC PF08954.11 KLO06993.1 - 0.0013 18.3 0.1 0.0023 17.5 0.1 1.3 1 0 0 1 1 1 1 Trimerisation motif EzrA PF06160.12 KLO06993.1 - 0.042 12.0 0.1 0.042 12.0 0.1 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TRPM_tetra PF16519.5 KLO06993.1 - 0.088 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Amino_oxidase PF01593.24 KLO06994.1 - 2.1e-33 116.3 0.0 2.4e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KLO06994.1 - 1.9e-12 47.2 0.0 1.9e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO06994.1 - 7.2e-08 32.4 0.0 7.2e-08 32.4 0.0 1.9 2 0 0 2 2 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KLO06994.1 - 9.7e-05 21.7 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KLO06994.1 - 0.00035 20.6 0.0 0.00035 20.6 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KLO06994.1 - 0.00072 18.9 0.7 0.013 14.8 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KLO06994.1 - 0.0032 16.3 0.0 0.0046 15.8 0.0 1.1 1 0 0 1 1 1 1 MCRA family Pyr_redox PF00070.27 KLO06994.1 - 0.028 15.0 0.0 0.028 15.0 0.0 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KLO06994.1 - 0.048 12.2 0.0 0.072 11.6 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) K_oxygenase PF13434.6 KLO06994.1 - 0.063 12.4 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KLO06994.1 - 0.086 11.5 0.2 0.15 10.7 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 KLO06994.1 - 0.18 10.7 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FMO-like PF00743.19 KLO06994.1 - 0.41 9.0 1.0 1.1 7.6 0.0 1.9 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Sterol_MT_C PF08498.10 KLO06995.1 - 1.7e-27 95.5 0.1 2.7e-27 94.9 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 KLO06995.1 - 3e-17 62.8 0.0 4.6e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO06995.1 - 1.1e-16 61.3 0.0 1.8e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO06995.1 - 5.4e-16 59.1 0.0 9.7e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KLO06995.1 - 1.4e-14 54.0 0.0 2e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KLO06995.1 - 5.6e-11 42.6 0.0 8e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO06995.1 - 2.4e-10 41.0 0.0 5.6e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO06995.1 - 2.7e-08 33.4 0.0 4.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KLO06995.1 - 8.7e-05 22.4 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KLO06995.1 - 0.00061 19.4 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.10 KLO06995.1 - 0.00076 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 KLO06995.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.17 KLO06995.1 - 0.0028 16.9 0.0 0.0056 15.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KLO06995.1 - 0.0076 17.3 0.0 0.021 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KLO06995.1 - 0.05 13.0 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.16 KLO06995.1 - 0.17 10.4 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Aldo_ket_red PF00248.21 KLO06996.1 - 2.9e-54 184.3 0.1 3e-53 180.9 0.1 2.2 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KLO06997.1 - 4.7e-72 242.7 0.0 5.3e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.21 KLO06997.1 - 0.13 12.2 0.0 0.44 10.6 0.0 1.9 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Aldo_ket_red PF00248.21 KLO06998.1 - 1.5e-71 241.0 0.0 1.8e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.21 KLO06998.1 - 0.19 11.7 1.2 0.87 9.6 0.1 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family HAD PF12710.7 KLO07000.1 - 1.5e-18 67.9 0.0 3.1e-18 66.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KLO07000.1 - 9.7e-05 22.0 0.0 0.00028 20.5 0.0 1.7 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KLO07000.1 - 0.00096 19.5 0.2 0.015 15.6 0.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase F-box-like PF12937.7 KLO07001.1 - 2e-05 24.4 1.1 2e-05 24.4 1.1 2.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO07001.1 - 0.00021 21.1 0.5 0.0012 18.7 0.5 2.3 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KLO07001.1 - 0.028 14.9 10.9 1.3 9.5 0.6 4.1 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO07002.1 - 2.2e-07 30.6 4.8 2.1e-06 27.5 0.4 3.4 2 1 0 2 2 2 2 F-box-like F-box-like PF12937.7 KLO07004.1 - 1.6e-05 24.7 0.0 4.9e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like Aldo_ket_red PF00248.21 KLO07005.1 - 1.1e-14 54.4 0.1 1.1e-14 54.3 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Arm PF00514.23 KLO07006.1 - 0.02 14.9 0.0 0.02 14.9 0.0 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RRN3 PF05327.11 KLO07006.1 - 0.93 8.0 2.4 14 4.1 0.3 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 HEAT PF02985.22 KLO07006.1 - 3.2 8.2 6.8 21 5.7 0.1 5.1 5 0 0 5 5 5 0 HEAT repeat DUF5127 PF17168.4 KLO07007.1 - 1.3e-52 178.9 0.4 2e-52 178.2 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO07007.1 - 8.2e-43 146.0 0.4 1.5e-42 145.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO07007.1 - 3.1e-35 122.1 0.7 5.8e-35 121.2 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO07007.1 - 0.00099 18.6 0.7 0.0053 16.3 0.7 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KLO07007.1 - 0.003 16.9 0.2 0.011 15.0 0.1 1.8 1 1 1 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF5518 PF17647.1 KLO07007.1 - 0.049 13.8 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5518) ATG19_autophagy PF12744.7 KLO07010.1 - 0.15 11.2 0.2 0.28 10.4 0.2 1.3 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding Exo5 PF09810.9 KLO07013.1 - 3.4e-65 221.0 0.2 4.2e-56 191.0 0.0 3.0 1 1 1 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KLO07013.1 - 0.0016 18.4 0.0 3.1 7.7 0.0 3.1 3 0 0 3 3 3 2 PD-(D/E)XK nuclease superfamily RseC_MucC PF04246.12 KLO07013.1 - 0.084 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Pkinase PF00069.25 KLO07014.1 - 2.4e-36 125.5 0.0 3.7e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO07014.1 - 1.6e-26 93.2 0.0 2.3e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO07014.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KLO07014.1 - 0.06 12.3 0.0 0.06 12.3 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KLO07014.1 - 0.064 13.2 0.0 0.3 11.0 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family HIT PF01230.23 KLO07015.1 - 1.5e-24 86.5 0.0 2.3e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KLO07015.1 - 2e-08 34.7 0.0 3.9e-08 33.8 0.0 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 KLO07015.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF2484 PF10658.9 KLO07016.1 - 0.0027 18.0 1.4 0.0055 17.0 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2484) GEN1_C PF18380.1 KLO07016.1 - 0.21 12.5 2.3 0.25 12.3 1.4 1.5 1 1 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain DUF5127 PF17168.4 KLO07018.1 - 8.1e-52 176.3 1.6 2.9e-51 174.4 1.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO07018.1 - 1.3e-47 161.6 0.1 2.6e-47 160.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO07018.1 - 2.3e-40 138.8 0.0 5.1e-40 137.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Glyco_hydr_116N PF12215.8 KLO07018.1 - 0.019 14.4 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF4964 PF16334.5 KLO07018.1 - 0.02 14.4 0.9 0.19 11.3 0.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4964) SUR7 PF06687.12 KLO07019.1 - 0.0049 16.5 0.1 0.005 16.5 0.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.9 KLO07019.1 - 0.088 11.6 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AAA PF00004.29 KLO07022.1 - 9.7e-61 204.0 0.0 2.5e-45 154.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KLO07022.1 - 3.3e-10 39.6 2.3 1.9e-05 24.4 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KLO07022.1 - 4.3e-07 30.5 0.7 0.0061 17.0 0.0 4.8 3 2 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KLO07022.1 - 2.2e-06 28.0 0.2 0.024 14.9 0.1 2.9 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.14 KLO07022.1 - 8.5e-06 25.8 0.0 0.025 14.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KLO07022.1 - 8e-05 23.2 0.0 0.039 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KLO07022.1 - 0.00015 21.5 0.0 0.0042 16.8 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 KLO07022.1 - 0.00017 21.5 0.3 0.039 13.9 0.1 2.9 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.6 KLO07022.1 - 0.00019 21.6 0.0 0.37 11.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.14 KLO07022.1 - 0.00072 19.7 0.0 0.017 15.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KLO07022.1 - 0.00076 19.5 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KLO07022.1 - 0.00079 19.7 0.1 0.49 10.6 0.0 3.2 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 KLO07022.1 - 0.0014 19.0 0.0 0.049 14.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATPase PF06745.13 KLO07022.1 - 0.002 17.5 0.0 0.0053 16.1 0.0 1.6 1 0 0 1 1 1 1 KaiC TIP49 PF06068.13 KLO07022.1 - 0.002 17.4 0.0 0.041 13.1 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KLO07022.1 - 0.0036 17.0 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 KLO07022.1 - 0.007 16.0 0.1 0.042 13.4 0.1 2.1 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KLO07022.1 - 0.0086 15.5 0.1 0.046 13.1 0.1 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KLO07022.1 - 0.03 14.0 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KLO07022.1 - 0.041 13.4 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KLO07022.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 KLO07022.1 - 0.077 12.9 0.0 0.67 9.8 0.0 2.4 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KLO07022.1 - 0.077 12.9 0.1 3.5 7.5 0.1 2.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 KLO07022.1 - 0.079 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 KLO07022.1 - 0.084 12.6 0.1 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 KLO07022.1 - 0.086 13.0 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_14 PF13173.6 KLO07022.1 - 0.16 12.0 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Gar1 PF04410.14 KLO07023.1 - 1.4e-37 128.9 0.0 1.7e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region RPN7 PF10602.9 KLO07024.1 - 2.1e-36 125.3 0.2 3.4e-36 124.6 0.2 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KLO07024.1 - 3.2e-16 59.8 0.5 1.5e-15 57.5 0.2 2.2 2 0 0 2 2 2 1 PCI domain GCH_III PF05165.12 KLO07024.1 - 0.00043 19.6 0.2 0.00074 18.9 0.2 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase III DUF2119 PF09892.9 KLO07024.1 - 0.02 14.3 0.6 0.057 12.8 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) CSN8_PSD8_EIF3K PF10075.9 KLO07024.1 - 0.03 14.3 0.0 0.03 14.3 0.0 2.8 4 0 0 4 4 4 0 CSN8/PSMD8/EIF3K family Cohesin_load PF10345.9 KLO07025.1 - 1.1e-06 27.4 0.0 7.3e-05 21.4 0.0 2.8 1 1 0 1 1 1 1 Cohesin loading factor GMC_oxred_N PF00732.19 KLO07026.1 - 6.8e-61 206.2 0.0 8.7e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO07026.1 - 8.7e-34 117.1 0.0 1.4e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KLO07026.1 - 0.00073 18.8 0.0 0.0021 17.4 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KLO07026.1 - 0.0022 17.1 0.1 0.004 16.3 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KLO07026.1 - 0.0061 15.8 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO07026.1 - 0.0063 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO07026.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO07026.1 - 0.041 13.0 0.1 0.064 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KLO07026.1 - 0.069 11.8 0.1 0.14 10.9 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 KLO07026.1 - 0.099 12.9 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain FYVE_2 PF02318.16 KLO07027.1 - 0.029 14.6 2.7 0.068 13.4 2.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger NAD_binding_4 PF07993.12 KLO07028.1 - 1.2e-33 116.4 0.0 1.8e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KLO07028.1 - 7.3e-31 107.2 0.0 3.1e-30 105.1 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KLO07028.1 - 2.7e-06 27.0 0.0 4.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KLO07028.1 - 0.0036 17.6 0.0 0.0084 16.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site YABBY PF04690.13 KLO07029.1 - 1.7e-09 38.5 3.3 1.7e-09 38.5 3.3 1.7 1 1 1 2 2 2 1 YABBY protein HMG_box PF00505.19 KLO07029.1 - 9.7e-07 29.1 8.8 3.8e-06 27.2 8.8 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box Ccdc124 PF06244.12 KLO07029.1 - 3.6e-05 24.3 2.9 3.6e-05 24.3 2.9 2.3 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_2 PF09011.10 KLO07029.1 - 0.00063 20.3 6.7 0.00063 20.3 6.7 1.9 2 1 0 2 2 2 1 HMG-box domain Glyco_transf_90 PF05686.12 KLO07031.1 - 3.2e-12 46.1 1.5 6.4e-11 41.8 1.4 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 90 USP8_dimer PF08969.11 KLO07032.1 - 1.9e-07 31.3 0.1 3.3e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain MIT PF04212.18 KLO07032.1 - 0.011 15.7 0.4 0.23 11.6 0.1 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF3086 PF11285.8 KLO07032.1 - 0.069 12.3 0.2 0.13 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) JAB PF01398.21 KLO07033.1 - 6.5e-18 64.8 0.0 8.9e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KLO07033.1 - 1.7e-07 31.0 0.0 2.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain adh_short PF00106.25 KLO07034.1 - 1.7e-42 145.1 0.0 2.2e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO07034.1 - 1.6e-35 122.8 0.0 2e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO07034.1 - 3.1e-13 50.0 0.0 4.4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KLO07034.1 - 0.0019 18.1 0.4 0.003 17.5 0.4 1.5 1 1 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 KLO07034.1 - 0.086 12.2 0.1 0.42 9.9 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.25 KLO07035.1 - 9.2e-39 132.9 0.0 1.2e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO07035.1 - 3.4e-31 108.6 0.0 4.5e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO07035.1 - 1.7e-12 47.6 0.0 2.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KLO07035.1 - 0.094 12.6 0.0 0.2 11.6 0.0 1.5 2 0 0 2 2 2 0 NAD(P)H-binding DAHP_synth_1 PF00793.20 KLO07036.1 - 1.3e-97 326.0 0.0 1.6e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PIH1 PF08190.12 KLO07037.1 - 7.5e-20 71.1 0.0 5.3e-17 61.8 0.0 2.3 2 0 0 2 2 2 2 PIH1 N-terminal domain Sugar_tr PF00083.24 KLO07040.1 - 1.5e-19 70.2 16.0 2.7e-14 52.9 3.6 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KLO07040.1 - 7.7e-19 67.8 41.0 1e-10 41.1 24.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Hydrolase_4 PF12146.8 KLO07041.1 - 2.7e-08 33.4 0.0 5.4e-06 25.8 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KLO07041.1 - 1.3e-05 25.9 1.1 2.1e-05 25.2 1.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO07041.1 - 4.8e-05 23.1 0.0 0.022 14.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KLO07041.1 - 0.0051 16.3 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Lipase_3 PF01764.25 KLO07041.1 - 0.0064 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KLO07041.1 - 0.021 14.4 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 KLO07041.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain CS PF04969.16 KLO07042.1 - 7.5e-07 30.1 0.0 1.2e-06 29.5 0.0 1.3 1 0 0 1 1 1 1 CS domain Forkhead_N PF08430.12 KLO07042.1 - 0.42 11.2 15.2 0.66 10.6 15.2 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region MFS_1 PF07690.16 KLO07043.1 - 4.2e-23 81.9 42.0 3.4e-15 55.8 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO07043.1 - 5e-16 58.6 22.1 2.4e-13 49.8 22.1 3.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2583 PF10762.9 KLO07043.1 - 0.49 10.8 3.4 0.33 11.4 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) p450 PF00067.22 KLO07044.1 - 1.1e-71 242.0 0.0 1.3e-71 241.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BPL_LplA_LipB PF03099.19 KLO07046.1 - 2.8e-05 24.0 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GTSE1_N PF15259.6 KLO07048.1 - 0.1 12.7 1.0 3.3 7.9 1.0 2.2 1 1 0 1 1 1 0 G-2 and S-phase expressed 1 ESR1_C PF12743.7 KLO07048.1 - 0.7 9.7 4.9 0.94 9.3 4.9 1.3 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal 2-oxoacid_dh PF00198.23 KLO07051.1 - 1.3e-50 172.0 0.0 5.1e-50 170.1 0.0 1.8 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KLO07051.1 - 9.8e-20 70.2 0.3 1.9e-19 69.3 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KLO07051.1 - 4.3e-10 39.8 0.1 1.1e-09 38.5 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KLO07051.1 - 8.6e-05 22.3 0.4 0.00026 20.8 0.1 1.9 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KLO07051.1 - 8.6e-05 23.2 0.0 0.0014 19.3 0.0 2.4 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 KLO07051.1 - 0.0022 17.2 0.3 0.0047 16.2 0.0 1.6 2 0 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Putative_PNPOx PF01243.20 KLO07052.1 - 0.00083 19.5 0.0 0.0031 17.7 0.0 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KLO07053.1 - 1.8e-07 31.2 0.0 3.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FtsK_4TM PF13491.6 KLO07054.1 - 0.4 10.4 11.5 0.29 10.8 1.0 2.3 1 1 1 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE DUF3328 PF11807.8 KLO07055.1 - 1.5e-08 34.7 0.1 1.9e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1275 PF06912.11 KLO07059.1 - 1.5e-30 106.5 15.8 1.8e-30 106.3 15.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Acyl_transf_3 PF01757.22 KLO07059.1 - 0.0017 17.5 14.3 0.013 14.6 5.9 2.1 1 1 1 2 2 2 2 Acyltransferase family STE3 PF02076.15 KLO07060.1 - 1.2e-67 228.2 7.6 1.3e-67 228.0 7.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor TctB PF07331.11 KLO07060.1 - 1.4 9.2 9.5 0.2 11.9 1.4 2.5 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family STE3 PF02076.15 KLO07061.1 - 2.5e-14 53.2 5.2 2.6e-14 53.1 5.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 KLO07062.1 - 2.8e-35 121.9 2.4 3.4e-35 121.7 2.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 KLO07064.1 - 1.4e-67 227.9 15.0 1.7e-67 227.7 15.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 KLO07065.1 - 1.3e-67 228.0 13.2 1.5e-67 227.9 13.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor Rad60-SLD_2 PF13881.6 KLO07066.1 - 1.1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KLO07066.1 - 0.062 13.1 0.0 0.34 10.7 0.0 2.1 1 1 0 1 1 1 0 Ubiquitin family PfkB PF00294.24 KLO07067.1 - 7.3e-08 32.1 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF3409 PF11889.8 KLO07069.1 - 0.031 14.2 0.0 3.3 7.7 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3409) BNIP3 PF06553.12 KLO07069.1 - 0.032 13.9 5.0 0.026 14.2 3.7 1.5 1 1 0 1 1 1 0 BNIP3 SPX PF03105.19 KLO07069.1 - 1 9.2 5.9 1.2 8.9 5.9 1.1 1 0 0 1 1 1 0 SPX domain AAA PF00004.29 KLO07070.1 - 3.6e-11 43.6 0.0 7.6e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KLO07070.1 - 0.0092 15.0 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KLO07070.1 - 0.046 14.1 0.0 0.14 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KLO07070.1 - 0.097 12.7 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KLO07070.1 - 0.4 11.0 3.2 1.9 8.8 0.0 2.8 2 1 1 3 3 3 0 AAA domain AAA PF00004.29 KLO07071.1 - 9.4e-11 42.3 0.0 2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KLO07071.1 - 0.02 15.3 0.1 0.12 12.8 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 KLO07071.1 - 0.039 12.9 0.0 0.069 12.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KLO07071.1 - 0.18 12.1 1.6 4 7.7 0.0 3.1 2 2 1 3 3 3 0 AAA domain AAA PF00004.29 KLO07072.1 - 2.1e-10 41.1 0.0 8.7e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KLO07072.1 - 0.052 13.9 0.2 0.2 12.0 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KLO07072.1 - 0.067 13.5 0.8 4.1 7.7 0.0 2.8 1 1 1 2 2 2 0 AAA domain Pkinase PF00069.25 KLO07075.1 - 3.1e-29 102.1 0.0 1.3e-22 80.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO07075.1 - 5.8e-29 101.2 0.0 1.7e-18 66.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase CENP-F_leu_zip PF10473.9 KLO07075.1 - 2.8e-05 24.1 3.7 5.8e-05 23.2 3.7 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APH PF01636.23 KLO07075.1 - 0.0021 18.0 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO07075.1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.6 2 0 0 2 2 2 0 RIO1 family FH2 PF02181.23 KLO07075.1 - 0.025 13.7 0.2 0.034 13.3 0.2 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain PI3K_P85_iSH2 PF16454.5 KLO07075.1 - 0.085 12.4 0.4 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BST2 PF16716.5 KLO07075.1 - 0.12 13.0 0.8 0.22 12.2 0.8 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Abhydrolase_6 PF12697.7 KLO07077.1 - 1.5e-17 64.9 2.1 1.8e-17 64.7 2.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO07077.1 - 3.7e-16 59.6 0.1 3.2e-15 56.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO07077.1 - 9.7e-10 38.1 0.0 1.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 NmrA PF05368.13 KLO07079.1 - 2.8e-35 122.0 1.1 8.4e-24 84.4 0.0 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KLO07079.1 - 2.8e-07 30.6 0.2 0.00055 19.9 0.1 2.3 1 1 1 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 KLO07079.1 - 0.022 14.2 0.2 0.097 12.1 0.1 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.10 KLO07079.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 KR domain Metallophos PF00149.28 KLO07080.1 - 1.7e-36 126.7 0.0 2.9e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Uso1_p115_head PF04869.14 KLO07081.1 - 0.042 13.0 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region DUF3421 PF11901.8 KLO07081.1 - 0.12 12.4 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3421) Mcp5_PH PF12814.7 KLO07082.1 - 3.3e-46 156.4 0.1 5.8e-46 155.6 0.1 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KLO07082.1 - 8.4e-07 29.5 0.0 2.2e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 PH domain Lebercilin PF15619.6 KLO07082.1 - 0.52 10.0 41.6 0.027 14.1 27.7 3.2 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease MAD PF05557.13 KLO07082.1 - 0.56 8.5 29.0 0.14 10.5 22.9 2.2 2 0 0 2 2 2 0 Mitotic checkpoint protein kleA_kleC PF17383.2 KLO07082.1 - 0.93 9.9 17.2 2.9 8.3 2.1 3.9 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A GAS PF13851.6 KLO07082.1 - 9.9 5.5 30.3 0.9 8.9 16.9 3.6 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding SNN_linker PF09050.10 KLO07086.1 - 0.0028 17.4 2.0 0.0042 16.8 0.2 2.1 2 0 0 2 2 2 1 Stannin unstructured linker DUF1652 PF07865.11 KLO07086.1 - 0.0034 17.2 0.8 0.008 16.0 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1652) DUF1570 PF07607.11 KLO07086.1 - 0.15 12.3 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) Transglut_core2 PF13369.6 KLO07089.1 - 1.4e-05 24.7 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KLO07089.1 - 0.0067 16.3 0.1 0.023 14.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like zf_UBZ PF18439.1 KLO07090.1 - 0.076 12.6 0.6 0.34 10.5 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Peptidase_M16 PF00675.20 KLO07091.1 - 9e-41 139.3 0.0 1.6e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KLO07091.1 - 6.7e-38 130.5 0.0 1.7e-37 129.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Ceramidase PF05875.12 KLO07092.1 - 9.8e-79 264.5 12.0 1.2e-78 264.2 12.0 1.0 1 0 0 1 1 1 1 Ceramidase FHA PF00498.26 KLO07093.1 - 2.4e-16 59.8 0.0 4.7e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KLO07093.1 - 3.3e-06 27.3 0.0 0.00012 22.3 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SAS4 PF15460.6 KLO07095.1 - 1.4e-05 25.1 7.6 4.6e-05 23.4 7.6 1.9 1 1 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.6 KLO07095.1 - 0.00023 21.8 3.0 0.00023 21.8 3.0 3.1 3 1 1 4 4 4 1 PEHE domain Trypan_PARP PF05887.11 KLO07095.1 - 0.0016 18.4 37.9 0.0016 18.4 37.9 3.6 2 1 1 3 3 3 1 Procyclic acidic repetitive protein (PARP) Gar1 PF04410.14 KLO07096.1 - 1.5e-36 125.5 0.4 1.5e-36 125.5 0.4 1.8 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region CmcI PF04989.12 KLO07096.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase EF_TS PF00889.19 KLO07097.1 - 6.8e-17 61.8 0.0 1.8e-16 60.4 0.0 1.7 1 1 1 2 2 2 1 Elongation factor TS UBA PF00627.31 KLO07097.1 - 0.0013 18.6 0.3 0.0023 17.8 0.3 1.4 1 0 0 1 1 1 1 UBA/TS-N domain C2-set_2 PF08205.12 KLO07097.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Glyco_hydro_6 PF01341.17 KLO07098.1 - 4.3e-101 338.7 0.8 5.4e-101 338.3 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 DHHC PF01529.20 KLO07099.1 - 9.6e-37 126.1 10.4 9.6e-37 126.1 10.4 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase FA_desaturase PF00487.24 KLO07101.1 - 3.2e-12 46.8 15.1 3.2e-12 46.8 15.1 2.1 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KLO07101.1 - 5.5e-07 29.6 0.0 1.8e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF755 PF05501.11 KLO07101.1 - 2 8.7 9.2 3 8.1 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Bromodomain PF00439.25 KLO07102.1 - 1.3e-42 143.8 5.4 6e-21 74.3 1.2 2.3 2 0 0 2 2 2 2 Bromodomain AT_hook PF02178.19 KLO07102.1 - 3.6 7.8 12.2 0.16 11.9 5.7 2.4 2 0 0 2 2 2 0 AT hook motif NAD_binding_8 PF13450.6 KLO07105.1 - 1e-10 41.6 0.0 2.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KLO07105.1 - 1.2e-09 37.1 0.7 1.5e-06 26.9 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like DAO PF01266.24 KLO07105.1 - 1.6e-06 27.9 0.3 0.39 10.2 0.1 3.1 2 1 1 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO07105.1 - 0.00015 21.1 0.0 0.0026 17.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KLO07105.1 - 0.016 15.2 0.0 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KLO07105.1 - 0.018 14.3 0.2 1.3 8.2 0.1 3.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KLO07105.1 - 0.023 13.8 0.1 0.6 9.2 0.0 2.7 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KLO07105.1 - 0.16 11.2 0.8 0.34 10.1 0.2 1.8 2 0 0 2 2 2 0 Thi4 family Pkinase_Tyr PF07714.17 KLO07106.1 - 3.9e-33 114.8 0.0 5.1e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO07106.1 - 9.4e-29 100.6 0.0 1.2e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO07106.1 - 0.0028 17.0 0.0 0.0038 16.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KLO07106.1 - 0.025 13.5 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KLO07106.1 - 0.074 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-MYND PF01753.18 KLO07107.1 - 4e-07 30.0 15.1 8.1e-07 29.0 15.1 1.6 1 0 0 1 1 1 1 MYND finger Fer4_13 PF13370.6 KLO07107.1 - 0.17 12.4 1.1 0.5 10.9 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I zf-MYND PF01753.18 KLO07108.1 - 5.1e-08 32.9 14.0 1e-07 31.9 14.0 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO07110.1 - 2.1e-07 30.9 15.6 3.5e-07 30.2 15.6 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO07111.1 - 3.1e-08 33.6 14.8 6e-08 32.7 14.8 1.5 1 0 0 1 1 1 1 MYND finger STAT_alpha PF01017.20 KLO07111.1 - 1.4 8.8 6.6 0.25 11.2 2.1 2.0 2 0 0 2 2 2 0 STAT protein, all-alpha domain zf-MYND PF01753.18 KLO07112.1 - 3.1e-08 33.6 13.5 5.7e-08 32.7 13.5 1.5 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 KLO07112.1 - 0.45 8.3 3.7 0.65 7.8 3.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.18 KLO07113.1 - 2.1e-08 34.1 13.4 4.2e-08 33.1 13.4 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO07114.1 - 7.1e-09 35.6 13.2 1.4e-08 34.7 13.2 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO07115.1 - 1.6e-07 31.3 15.9 3e-07 30.4 15.9 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO07116.1 - 3.3e-09 36.7 13.5 6.3e-09 35.8 13.5 1.5 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 KLO07118.1 - 0.033 14.1 0.0 0.083 12.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KLO07118.1 - 0.2 11.6 1.7 13 5.8 0.1 3.0 3 0 0 3 3 3 0 F-box domain Pkinase_Tyr PF07714.17 KLO07119.1 - 2.3e-39 135.2 0.0 3.2e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO07119.1 - 6.2e-38 130.7 0.0 9.5e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO07119.1 - 0.0067 15.8 0.0 0.015 14.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO07119.1 - 0.027 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO07119.1 - 0.2 11.5 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KLO07120.1 - 1.4e-43 149.2 0.0 1.9e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO07120.1 - 8.1e-41 140.0 0.0 1.1e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO07120.1 - 0.0025 17.2 0.0 0.0096 15.3 0.0 1.8 1 1 0 1 1 1 1 Kinase-like ECH_1 PF00378.20 KLO07121.1 - 2.6e-54 184.2 0.0 3.4e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KLO07121.1 - 1.7e-28 100.1 0.0 2e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TPX2 PF06886.11 KLO07126.1 - 4.2e-09 36.5 24.3 1.9e-08 34.4 19.9 2.3 2 0 0 2 2 2 2 Targeting protein for Xklp2 (TPX2) Porph_ging PF09697.10 KLO07126.1 - 0.18 12.4 1.7 0.23 12.0 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) Sas10 PF09368.10 KLO07126.1 - 0.31 11.5 6.1 4.3 7.9 1.7 3.0 3 0 0 3 3 3 0 Sas10 C-terminal domain Peptidase_M76 PF09768.9 KLO07128.1 - 3.5e-39 134.3 0.2 4.5e-39 134.0 0.2 1.1 1 0 0 1 1 1 1 Peptidase M76 family PRIMA1 PF16101.5 KLO07132.1 - 6.8 6.7 7.6 1.1 9.3 3.0 1.9 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 Helitron_like_N PF14214.6 KLO07134.1 - 8e-22 78.4 0.0 1.1e-21 78.0 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus CobA_CobO_BtuR PF02572.15 KLO07135.1 - 0.027 14.7 0.0 0.037 14.3 0.0 1.2 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP zf-NF-X1 PF01422.17 KLO07135.1 - 1.5 9.0 5.8 2.9 8.0 2.3 2.3 2 0 0 2 2 2 0 NF-X1 type zinc finger AAA_30 PF13604.6 KLO07136.1 - 8.7e-08 32.1 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 KLO07136.1 - 9.4e-08 31.6 0.0 2e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 KLO07136.1 - 4.3e-06 27.1 0.0 6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KLO07136.1 - 0.0095 15.2 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 KLO07136.1 - 0.012 16.0 0.2 0.052 14.0 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KLO07136.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KLO07136.1 - 0.016 15.0 0.2 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_5 PF07728.14 KLO07136.1 - 0.052 13.5 0.1 0.22 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KLO07136.1 - 0.055 13.8 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KLO07136.1 - 0.1 12.9 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KLO07136.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KLO07136.1 - 0.13 12.2 0.0 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 NTPase Ribonuc_red_sm PF00268.21 KLO07137.1 - 2.6e-119 397.8 0.0 3.1e-119 397.5 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain F-box-like PF12937.7 KLO07139.1 - 0.011 15.6 0.4 0.027 14.4 0.4 1.6 1 0 0 1 1 1 0 F-box-like Pyr_excise PF03013.14 KLO07140.1 - 0.14 12.1 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase CxC2 PF18803.1 KLO07142.1 - 5.1e-18 65.2 0.0 7.6e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO07142.1 - 0.00016 21.8 0.2 0.00025 21.2 0.2 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases zf-UBR PF02207.20 KLO07142.1 - 5.1 7.3 13.7 0.28 11.4 7.0 2.4 2 1 1 3 3 3 0 Putative zinc finger in N-recognin (UBR box) DUF2797 PF10977.8 KLO07142.1 - 6.3 6.6 7.2 1.3 8.9 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2797) F-box-like PF12937.7 KLO07143.1 - 2.9e-06 27.1 0.0 9.2e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like DUF3606 PF12244.8 KLO07143.1 - 0.17 11.8 0.8 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) F-box PF00646.33 KLO07143.1 - 2.3 8.2 5.0 5.3 7.0 0.2 3.1 2 1 0 2 2 2 0 F-box domain zinc_ribbon_12 PF11331.8 KLO07147.1 - 0.12 12.2 0.1 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain Fungal_trans_2 PF11951.8 KLO07149.1 - 0.029 13.2 0.3 0.056 12.3 0.3 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Nuclease_act PF08133.11 KLO07149.1 - 0.035 14.3 0.0 0.071 13.3 0.0 1.5 1 0 0 1 1 1 0 Anticodon nuclease activator family MFS_1 PF07690.16 KLO07150.1 - 3.7e-29 101.8 27.4 3.7e-29 101.8 27.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily PhoD PF09423.10 KLO07151.1 - 2e-104 349.4 0.2 2.4e-104 349.1 0.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KLO07151.1 - 2.2e-24 85.8 0.0 4.1e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KLO07151.1 - 0.0034 17.9 0.0 0.011 16.3 0.0 1.9 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Terpene_synth_C PF03936.16 KLO07152.1 - 1e-09 38.1 0.0 1.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Het-C PF07217.11 KLO07154.1 - 4.6e-217 722.0 0.0 5.7e-217 721.7 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C SKG6 PF08693.10 KLO07155.1 - 0.083 12.3 0.4 0.2 11.1 0.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SKG6 PF08693.10 KLO07156.1 - 0.0017 17.8 2.2 0.0035 16.7 2.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Shisa PF13908.6 KLO07156.1 - 0.036 14.3 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator COX8 PF02285.15 KLO07156.1 - 0.22 11.4 0.1 0.22 11.4 0.1 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII DAG1 PF05454.11 KLO07156.1 - 5.9 6.2 5.7 0.64 9.3 0.2 1.9 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) F-box-like PF12937.7 KLO07157.1 - 1.8e-05 24.5 0.4 5.2e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO07157.1 - 0.004 17.0 0.1 0.12 12.3 0.0 2.7 2 0 0 2 2 2 1 F-box domain HMG_box PF00505.19 KLO07158.1 - 2.2e-12 47.2 1.0 2.9e-12 46.8 1.0 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO07158.1 - 8.2e-07 29.5 0.8 9.7e-07 29.3 0.8 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 KLO07158.1 - 0.01 15.8 0.2 0.011 15.7 0.2 1.1 1 0 0 1 1 1 0 HMG (high mobility group) box 5 DUF2057 PF09829.9 KLO07158.1 - 0.023 14.9 0.2 0.028 14.6 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) AHH PF14412.6 KLO07158.1 - 0.049 13.7 0.2 0.06 13.4 0.2 1.1 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Cellulase PF00150.18 KLO07159.1 - 2.4e-10 40.3 0.0 1.4e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Zn_clus PF00172.18 KLO07161.1 - 0.00034 20.7 8.3 0.00054 20.0 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO07162.1 - 2.6e-06 27.4 8.3 2.6e-06 27.4 8.3 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4211 PF13926.6 KLO07162.1 - 1.4 9.0 6.3 9.6 6.3 6.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4211) Zn_clus PF00172.18 KLO07163.1 - 1.8e-05 24.7 11.3 3.2e-05 23.9 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhoU_div PF01865.16 KLO07164.1 - 0.24 10.7 0.0 0.94 8.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF47 Zn_clus PF00172.18 KLO07165.1 - 3.9e-06 26.9 11.8 3.9e-06 26.9 11.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cullin_Nedd8 PF10557.9 KLO07165.1 - 0.013 15.5 0.5 0.66 10.1 0.5 2.7 2 1 1 3 3 3 0 Cullin protein neddylation domain Zn_clus PF00172.18 KLO07168.1 - 3.7e-06 27.0 12.1 9.5e-06 25.6 12.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5528 PF17666.1 KLO07169.1 - 0.067 13.1 0.3 0.085 12.8 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5528) LURAP PF14854.6 KLO07171.1 - 0.00075 19.4 0.3 0.0013 18.7 0.2 1.4 1 1 0 1 1 1 1 Leucine rich adaptor protein Zn_clus PF00172.18 KLO07172.1 - 2.2e-07 30.9 10.4 2.2e-07 30.9 10.4 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2770 PF10968.8 KLO07174.1 - 0.15 12.1 0.4 0.27 11.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2770) Rot1 PF10681.9 KLO07175.1 - 3.7e-53 180.2 0.5 4.5e-53 179.9 0.5 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal F-box_4 PF15966.5 KLO07176.1 - 0.0011 18.9 0.1 0.0031 17.4 0.1 1.8 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KLO07176.1 - 0.035 14.0 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like Proteasome PF00227.26 KLO07178.1 - 1.9e-33 115.6 0.1 2.6e-33 115.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit DUF2121 PF09894.9 KLO07178.1 - 0.23 11.0 0.4 6.5 6.2 0.1 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2121) Pkinase_Tyr PF07714.17 KLO07181.1 - 1e-37 129.9 0.0 1.6e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO07181.1 - 3.1e-36 125.1 0.0 5.2e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO07181.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO07181.1 - 0.0087 14.9 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase SLATT_5 PF18160.1 KLO07182.1 - 0.99 8.7 5.7 0.21 10.9 0.7 2.3 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2070 PF09843.9 KLO07182.1 - 1.3 7.2 7.7 2.1 6.6 7.7 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2976 PF11190.8 KLO07182.1 - 3.2 7.6 7.3 1.6 8.5 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Fim-adh_lectin PF09222.10 KLO07184.1 - 0.0024 17.4 0.0 0.017 14.6 0.0 2.1 2 0 0 2 2 2 1 Fimbrial adhesin F17-AG, lectin domain Metal_CEHH PF14455.6 KLO07184.1 - 0.024 14.2 0.1 0.043 13.4 0.1 1.3 1 0 0 1 1 1 0 Predicted metal binding domain CDC73_C PF05179.14 KLO07184.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal FtsK_gamma PF09397.10 KLO07187.1 - 0.063 13.1 0.1 0.19 11.5 0.1 1.8 2 0 0 2 2 2 0 Ftsk gamma domain RNA_pol_Rpb1_7 PF04990.12 KLO07187.1 - 0.15 12.1 1.2 0.29 11.1 0.2 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 7 PBECR2 PF18810.1 KLO07188.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 HisG PF01634.18 KLO07189.1 - 1.4e-51 174.6 0.0 1.9e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KLO07189.1 - 1.4e-27 95.6 0.0 3e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 KLO07189.1 - 0.00048 20.1 0.1 0.00066 19.7 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Methyltransf_20 PF12147.8 KLO07189.1 - 0.21 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase UQ_con PF00179.26 KLO07190.1 - 1.5e-42 144.6 0.0 1.9e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KLO07190.1 - 1.1e-14 53.9 0.2 2e-14 53.1 0.2 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KLO07190.1 - 0.0024 17.6 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Calsarcin PF05556.11 KLO07190.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) peroxidase PF00141.23 KLO07197.1 - 4.5e-29 101.8 0.0 1.2e-28 100.4 0.0 1.8 2 1 0 2 2 2 1 Peroxidase Peroxidase_ext PF11895.8 KLO07197.1 - 1.6e-26 92.0 2.1 3e-26 91.2 1.4 1.9 2 0 0 2 2 2 1 Fungal peroxidase extension region CcmB PF03379.13 KLO07199.1 - 0.04 13.4 2.7 0.054 13.0 2.7 1.1 1 0 0 1 1 1 0 CcmB protein TFIID_30kDa PF03540.13 KLO07204.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit BTB PF00651.31 KLO07206.1 - 0.00089 19.5 0.0 0.0026 17.9 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07207.1 - 2.6e-05 24.4 0.0 5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain OSTMP1 PF09777.9 KLO07207.1 - 0.041 13.3 1.1 0.91 8.9 0.0 2.2 1 1 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor BTB PF00651.31 KLO07208.1 - 3.6e-07 30.4 0.0 6.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07209.1 - 6.1e-05 23.2 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07210.1 - 0.00039 20.6 0.0 0.0009 19.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07211.1 - 3.2e-05 24.1 0.0 6.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Abhydrolase_1 PF00561.20 KLO07211.1 - 0.086 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold BTB PF00651.31 KLO07212.1 - 9.3e-06 25.9 0.1 2.3e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO07213.1 - 0.002 18.4 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07214.1 - 0.00099 19.3 0.0 0.0034 17.6 0.0 1.8 1 1 1 2 2 2 2 BTB/POZ domain BTB PF00651.31 KLO07215.1 - 0.021 15.1 0.0 0.49 10.6 0.0 2.4 3 0 0 3 3 3 0 BTB/POZ domain RAMP PF04901.13 KLO07215.1 - 0.021 14.8 0.8 1 9.4 0.0 3.2 3 1 0 3 3 3 0 Receptor activity modifying family PsaD PF02531.16 KLO07215.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 PsaD BTB PF00651.31 KLO07216.1 - 0.0014 18.8 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07217.1 - 9.3e-05 22.6 0.1 0.00025 21.2 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO07218.1 - 6.9e-06 26.3 0.0 2.6e-05 24.4 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO07219.1 - 1.2e-06 28.7 0.0 2.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07220.1 - 2.9e-05 24.2 0.0 4.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF1419 PF07215.11 KLO07221.1 - 0.021 14.9 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1419) BTB PF00651.31 KLO07221.1 - 0.044 14.0 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain UreE_N PF02814.15 KLO07221.1 - 0.14 11.8 0.0 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain BTB PF00651.31 KLO07222.1 - 2.4e-09 37.4 0.8 3.2e-08 33.8 0.2 2.2 1 1 1 2 2 2 1 BTB/POZ domain Chlam_OMP6 PF03504.13 KLO07222.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 BTB PF00651.31 KLO07225.1 - 0.0011 19.2 0.3 0.0028 17.9 0.3 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07226.1 - 5.6e-08 33.0 0.1 1.4e-07 31.7 0.1 1.6 1 1 0 1 1 1 1 BTB/POZ domain Oxidored_FMN PF00724.20 KLO07227.1 - 2.6e-92 309.7 0.0 3e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Rhabdo_NV PF02484.15 KLO07227.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Rhabdovirus Non-virion protein Lipase_3 PF01764.25 KLO07228.1 - 4.8e-15 55.7 0.0 8.9e-15 54.8 0.0 1.4 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KLO07228.1 - 0.038 14.6 0.1 0.048 14.3 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family BTB PF00651.31 KLO07229.1 - 0.00076 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain APH PF01636.23 KLO07231.1 - 3.9e-06 27.0 0.0 8.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family F-box-like PF12937.7 KLO07235.1 - 1.8e-06 27.7 0.2 5.1e-06 26.3 0.2 1.8 1 0 0 1 1 1 1 F-box-like DUF4122 PF13498.6 KLO07235.1 - 0.046 13.4 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) Fungal_trans PF04082.18 KLO07236.1 - 3.2e-18 65.7 1.8 6.2e-18 64.8 1.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO07236.1 - 4e-06 26.8 12.0 7e-06 26.1 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 KLO07238.1 - 3.8e-14 53.0 0.0 6.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KLO07238.1 - 1e-06 27.9 0.0 1.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KLO07238.1 - 0.0041 16.2 0.0 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Peptidase_S9 PF00326.21 KLO07238.1 - 0.0097 15.4 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KLO07238.1 - 0.018 13.9 0.0 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Esterase PF00756.20 KLO07238.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 KLO07238.1 - 0.14 11.4 0.0 14 4.8 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 3HBOH PF10605.9 KLO07238.1 - 0.3 9.3 0.0 0.45 8.7 0.0 1.2 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) CNH PF00780.22 KLO07239.1 - 1.1e-76 258.1 0.0 1.9e-76 257.3 0.0 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KLO07239.1 - 2.3e-44 150.8 0.1 4.5e-44 149.8 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KLO07239.1 - 3.5e-35 121.9 0.0 5.4e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KLO07239.1 - 7.5e-15 54.8 0.0 2e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2442 PF10387.9 KLO07239.1 - 0.024 14.9 0.0 0.069 13.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) PH_13 PF16652.5 KLO07239.1 - 0.093 12.5 0.1 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain TAL_FSA PF00923.19 KLO07240.1 - 9.1e-09 35.1 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase WD40 PF00400.32 KLO07241.1 - 2.5e-36 123.0 13.8 3.4e-07 30.8 0.2 7.9 7 0 0 7 7 7 5 WD domain, G-beta repeat NACHT PF05729.12 KLO07241.1 - 3.6e-13 49.8 0.4 7.8e-05 22.6 0.0 3.4 2 2 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO07241.1 - 7.5e-10 39.4 0.5 0.00012 22.5 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain ANAPC4_WD40 PF12894.7 KLO07241.1 - 2.4e-09 37.4 0.1 0.29 11.5 0.0 5.5 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 KLO07241.1 - 3.3e-09 37.1 0.0 0.0039 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KLO07241.1 - 7e-08 33.0 0.0 0.002 18.6 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KLO07241.1 - 2.6e-06 28.0 0.0 0.032 14.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KLO07241.1 - 9.1e-06 25.9 0.0 0.08 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KLO07241.1 - 1.4e-05 24.4 0.0 0.18 11.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin APS_kinase PF01583.20 KLO07241.1 - 2.4e-05 24.3 0.0 0.0073 16.2 0.0 2.7 3 0 0 3 3 2 1 Adenylylsulphate kinase RNA_helicase PF00910.22 KLO07241.1 - 4e-05 23.9 0.0 0.59 10.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase NB-ARC PF00931.22 KLO07241.1 - 0.00011 21.5 0.0 0.018 14.3 0.0 2.6 2 1 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 KLO07241.1 - 0.00013 21.7 0.1 0.21 11.3 0.1 2.5 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KLO07241.1 - 0.0005 19.8 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 KLO07241.1 - 0.00059 19.9 0.0 0.041 13.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KLO07241.1 - 0.0014 18.4 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Ge1_WD40 PF16529.5 KLO07241.1 - 0.002 17.2 0.7 3.2 6.6 0.0 4.3 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Ploopntkinase3 PF18751.1 KLO07241.1 - 0.002 18.1 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 KLO07241.1 - 0.0047 16.7 0.1 0.28 10.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 KLO07241.1 - 0.0055 15.8 0.0 0.079 12.0 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KLO07241.1 - 0.0056 16.3 0.2 4.1 6.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KLO07241.1 - 0.0062 17.0 0.0 1.4 9.4 0.0 2.6 2 0 0 2 2 2 1 ABC transporter MeaB PF03308.16 KLO07241.1 - 0.0066 15.5 0.0 0.39 9.6 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 KLO07241.1 - 0.0091 15.3 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PPV_E1_C PF00519.17 KLO07241.1 - 0.0094 14.8 0.0 0.35 9.7 0.0 2.2 2 0 0 2 2 2 1 Papillomavirus helicase AAA_17 PF13207.6 KLO07241.1 - 0.013 15.9 0.2 1.9 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KLO07241.1 - 0.024 14.6 0.0 2.1 8.2 0.0 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain Torsin PF06309.11 KLO07241.1 - 0.025 14.7 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Torsin MMR_HSR1 PF01926.23 KLO07241.1 - 0.028 14.5 0.0 10 6.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase KAP_NTPase PF07693.14 KLO07241.1 - 0.04 13.2 2.7 0.62 9.2 0.4 2.6 2 1 0 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.6 KLO07241.1 - 0.045 14.1 0.0 3.2 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KLO07241.1 - 0.05 13.0 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family IL3 PF02059.15 KLO07241.1 - 0.053 13.6 0.1 7.5 6.6 0.0 3.0 3 0 0 3 3 2 0 Interleukin-3 PD40 PF07676.12 KLO07241.1 - 0.074 13.0 1.3 45 4.1 0.1 4.2 5 0 0 5 5 3 0 WD40-like Beta Propeller Repeat AAA_PrkA PF08298.11 KLO07241.1 - 0.11 11.4 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain RsgA_GTPase PF03193.16 KLO07241.1 - 0.17 11.8 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 KLO07241.1 - 0.17 11.9 0.0 18 5.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KLO07241.1 - 0.21 11.5 0.0 1.2 9.1 0.0 2.3 3 0 0 3 3 2 0 NTPase CE2_N PF17996.1 KLO07243.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal DUF2567 PF10821.8 KLO07243.1 - 0.024 14.7 1.5 0.027 14.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) DUF4448 PF14610.6 KLO07243.1 - 0.069 12.9 0.1 0.097 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Hexapep PF00132.24 KLO07244.1 - 2.1e-11 43.1 21.9 8e-07 28.5 0.9 4.6 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KLO07244.1 - 3e-06 26.9 14.4 0.00061 19.5 0.5 3.9 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KLO07244.1 - 1.2e-05 24.4 0.0 1.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase GCV_T PF01571.21 KLO07245.1 - 7.3e-85 284.4 0.0 8.9e-85 284.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KLO07245.1 - 3e-22 78.3 0.1 7.1e-22 77.1 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain MFS_1 PF07690.16 KLO07248.1 - 4e-41 141.1 23.8 4e-41 141.1 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO07248.1 - 9.3e-17 61.0 7.9 9.3e-17 61.0 7.9 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter RseC_MucC PF04246.12 KLO07248.1 - 0.42 10.6 2.9 11 5.9 0.1 3.4 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Erythro-docking PF09277.11 KLO07254.1 - 0.025 14.5 0.1 0.077 12.9 0.1 1.8 1 0 0 1 1 1 0 Erythronolide synthase, docking Guanylate_cyc_2 PF09778.9 KLO07255.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Guanylylate cyclase DUF294_C PF10335.9 KLO07255.1 - 0.1 12.3 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain F-box-like PF12937.7 KLO07257.1 - 1.2e-05 25.1 0.2 6.9e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO07258.1 - 0.00068 19.5 0.1 0.0035 17.2 0.0 2.3 2 0 0 2 2 2 1 F-box-like DUF3381 PF11861.8 KLO07258.1 - 0.042 13.6 0.1 0.078 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.14 KLO07258.1 - 0.65 8.2 9.4 0.97 7.6 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KLO07258.1 - 0.67 8.0 15.7 0.97 7.5 15.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KLO07258.1 - 0.84 9.0 9.9 1.2 8.5 9.9 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KLO07258.1 - 5 6.4 10.6 8.1 5.7 10.6 1.2 1 0 0 1 1 1 0 BUD22 F-box-like PF12937.7 KLO07259.1 - 1.3e-06 28.2 0.1 6.7e-06 25.9 0.1 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO07259.1 - 0.0051 16.7 2.5 8.1 6.4 0.0 3.8 3 0 0 3 3 3 2 F-box domain QueF_N PF14819.6 KLO07259.1 - 0.071 13.4 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term DUF2371 PF10177.9 KLO07260.1 - 0.071 13.3 1.3 0.7 10.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Metallophos PF00149.28 KLO07261.1 - 1.6e-11 45.1 2.1 3.7e-11 43.9 2.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Wbp11 PF09429.10 KLO07262.1 - 2.4e-23 82.3 12.2 5.6e-23 81.1 12.2 1.6 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 KLO07262.1 - 2e-12 47.7 16.8 2e-12 47.7 16.8 6.4 5 2 0 5 5 5 1 mRNA biogenesis factor TMF_TATA_bd PF12325.8 KLO07262.1 - 0.087 13.0 5.6 0.16 12.2 5.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding F-box-like PF12937.7 KLO07263.1 - 5e-06 26.3 0.3 2e-05 24.4 0.3 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO07263.1 - 0.14 12.1 2.1 21 5.1 0.0 3.3 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO07264.1 - 3.4e-07 30.0 0.2 8.9e-07 28.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO07264.1 - 0.027 14.3 1.3 7.5 6.6 0.2 2.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO07265.1 - 0.0001 22.1 0.0 0.00041 20.2 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO07265.1 - 0.049 13.5 0.4 58 3.7 0.0 3.7 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.7 KLO07265.1 - 1.2 9.6 6.5 1.7 9.2 0.1 4.2 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO07266.1 - 2.4e-07 30.5 0.0 8.7e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 F-box-like Chalcone_2 PF16035.5 KLO07266.1 - 0.05 13.4 0.2 0.093 12.5 0.2 1.3 1 0 0 1 1 1 0 Chalcone isomerase like LRR_4 PF12799.7 KLO07266.1 - 4.9 7.7 5.0 7.8 7.1 0.1 3.8 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO07267.1 - 2.1e-07 30.7 2.3 2.7e-07 30.4 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO07267.1 - 0.0038 17.1 1.9 15 5.6 0.3 3.9 2 1 1 3 3 3 3 F-box domain BORCS8 PF10167.9 KLO07267.1 - 0.058 13.3 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 F-box-like PF12937.7 KLO07268.1 - 4.3e-05 23.3 0.0 0.00012 21.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like DUF3747 PF12565.8 KLO07268.1 - 0.043 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) F-box-like PF12937.7 KLO07269.1 - 2.4e-07 30.6 1.6 6.3e-07 29.2 0.0 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO07269.1 - 0.057 13.3 0.6 5.8 6.9 0.2 2.9 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 KLO07270.1 - 0.046 14.2 0.3 23 5.6 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO07271.1 - 9.8e-07 28.6 0.0 2.6e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO07271.1 - 2.2 8.2 4.6 16 5.5 0.5 2.9 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO07272.1 - 0.011 15.6 1.2 0.029 14.3 0.3 2.4 2 1 0 2 2 2 0 F-box-like LRR_4 PF12799.7 KLO07274.1 - 0.0012 19.2 7.1 7.9 7.1 0.1 5.6 3 3 2 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO07275.1 - 0.0012 18.7 0.2 0.0035 17.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like Polysacc_deac_1 PF01522.21 KLO07277.1 - 7.2e-31 106.7 0.0 1.7e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2316 PF10078.9 KLO07277.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF3606 PF12244.8 KLO07277.1 - 0.58 10.1 1.6 0.64 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) SR-25 PF10500.9 KLO07277.1 - 8.6 5.9 11.5 14 5.2 11.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Polysacc_deac_1 PF01522.21 KLO07278.1 - 4.8e-29 100.8 0.0 8.5e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2316 PF10078.9 KLO07278.1 - 0.096 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) CxC2 PF18803.1 KLO07282.1 - 2.4e-10 40.5 0.0 4.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF3912 PF13051.6 KLO07285.1 - 0.0086 16.3 0.4 0.03 14.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) Spt5-NGN PF03439.13 KLO07286.1 - 2.5e-09 36.9 0.0 5.8e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KLO07286.1 - 1.6e-06 27.8 18.8 0.023 14.6 4.0 4.6 4 0 0 4 4 4 3 KOW motif DUF3912 PF13051.6 KLO07286.1 - 0.34 11.2 2.1 14 6.0 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3912) YajC PF02699.15 KLO07286.1 - 9.8 6.1 6.9 41 4.2 0.0 3.6 3 1 0 4 4 4 0 Preprotein translocase subunit DUF563 PF04577.14 KLO07291.1 - 4.6e-18 66.1 0.0 9.2e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Hexapep PF00132.24 KLO07292.1 - 9.3e-12 44.2 20.8 8e-07 28.5 0.9 4.6 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KLO07292.1 - 3e-06 26.9 14.4 0.00061 19.5 0.5 3.9 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KLO07292.1 - 1.2e-05 24.4 0.0 1.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 L-fucokinase 2C_adapt PF08793.10 KLO07294.1 - 0.49 10.6 5.1 0.41 10.9 0.2 2.8 3 0 0 3 3 3 0 2-cysteine adaptor domain WI12 PF07107.11 KLO07295.1 - 0.023 14.8 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Wound-induced protein WI12 Claudin_2 PF13903.6 KLO07295.1 - 0.62 9.8 7.2 0.21 11.3 4.2 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Pkinase_Tyr PF07714.17 KLO07299.1 - 4.7e-41 140.8 0.0 6.4e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO07299.1 - 2e-40 138.8 0.0 3.3e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO07299.1 - 0.001 18.4 0.0 0.0028 17.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO07299.1 - 0.004 16.0 0.0 0.006 15.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KLO07299.1 - 0.0092 15.6 0.1 0.085 12.5 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Xan_ur_permease PF00860.20 KLO07302.1 - 1.5e-29 102.9 23.2 1.9e-28 99.3 21.9 2.4 2 1 0 2 2 2 1 Permease family Sulfate_transp PF00916.20 KLO07302.1 - 0.0025 16.6 3.5 0.0025 16.6 3.5 2.8 2 1 1 3 3 3 2 Sulfate permease family MFS_MOT1 PF16983.5 KLO07302.1 - 0.012 16.0 4.0 0.012 16.0 4.0 2.6 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily MscS_porin PF12795.7 KLO07303.1 - 0.26 10.8 0.0 0.35 10.4 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain MADF_DNA_bdg PF10545.9 KLO07304.1 - 0.047 14.0 0.4 0.075 13.4 0.4 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4886 PF16227.5 KLO07304.1 - 0.084 12.0 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) Complex1_LYR PF05347.15 KLO07304.1 - 0.25 11.4 3.2 8.4 6.5 0.3 2.5 1 1 1 2 2 2 0 Complex 1 protein (LYR family) NIT PF08376.10 KLO07305.1 - 0.035 14.6 0.6 0.047 14.2 0.6 1.3 1 1 0 1 1 1 0 Nitrate and nitrite sensing DUF5109 PF17134.4 KLO07305.1 - 0.06 13.3 0.0 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5109) PPR_2 PF13041.6 KLO07306.1 - 0.18 12.0 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family Adaptin_N PF01602.20 KLO07309.1 - 0.08 11.5 0.5 0.13 10.8 0.5 1.2 1 0 0 1 1 1 0 Adaptin N terminal region F-box-like PF12937.7 KLO07312.1 - 2.8e-06 27.1 4.8 1.7e-05 24.6 4.8 2.3 1 1 0 1 1 1 1 F-box-like DUF1825 PF08855.10 KLO07312.1 - 0.0063 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1825) Rad21_Rec8 PF04824.16 KLO07312.1 - 0.17 11.2 0.0 0.39 10.0 0.0 1.6 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein F-box PF00646.33 KLO07312.1 - 2 8.4 4.7 14 5.7 0.3 3.4 3 0 0 3 3 3 0 F-box domain APH PF01636.23 KLO07313.1 - 9.6e-09 35.5 1.8 0.004 17.1 0.0 3.6 4 0 0 4 4 4 2 Phosphotransferase enzyme family VIT PF08487.10 KLO07314.1 - 1.3e-27 96.2 0.0 3.6e-27 94.8 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KLO07314.1 - 1.2e-21 77.3 0.0 3e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KLO07314.1 - 6.7e-15 55.8 0.0 1.4e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KLO07314.1 - 7.4e-12 45.9 0.0 4.7e-11 43.3 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KLO07314.1 - 7.5e-06 25.5 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VIT_2 PF13757.6 KLO07314.1 - 0.00025 20.9 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain PGI PF00342.19 KLO07314.1 - 0.14 10.7 0.1 0.22 10.0 0.1 1.2 1 0 0 1 1 1 0 Phosphoglucose isomerase Pkinase PF00069.25 KLO07315.1 - 0.0024 17.3 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO07315.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Mesothelin PF06060.12 KLO07315.1 - 0.044 12.0 0.0 0.068 11.4 0.0 1.2 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) CENP-Q PF13094.6 KLO07315.1 - 0.13 12.5 0.1 0.75 10.0 0.0 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Pkinase_Tyr PF07714.17 KLO07316.1 - 2.9e-40 138.2 0.0 3.8e-33 114.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KLO07316.1 - 1.8e-39 135.7 0.0 1.3e-31 109.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KLO07316.1 - 1.2e-06 28.1 0.0 6.7e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 KLO07316.1 - 0.028 14.0 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cation_efflux PF01545.21 KLO07318.1 - 8e-17 61.6 10.9 1e-16 61.3 10.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KLO07318.1 - 4.5e-11 42.7 0.4 1.5e-10 41.0 0.4 1.9 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DPBB_1 PF03330.18 KLO07319.1 - 1.1e-07 32.0 0.1 1.8e-07 31.3 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 KLO07319.1 - 0.088 12.9 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Cerato-platanin HBB PF06777.11 KLO07320.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Helical and beta-bridge domain Ustilago_mating PF05722.12 KLO07323.1 - 0.09 12.3 0.5 0.14 11.7 0.5 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein F-box-like PF12937.7 KLO07324.1 - 4.7e-07 29.6 0.3 1.6e-06 27.9 0.3 2.0 1 0 0 1 1 1 1 F-box-like Robl_LC7 PF03259.17 KLO07324.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain zf-C4H2 PF10146.9 KLO07325.1 - 6.7e-08 33.1 4.1 6.7e-08 33.1 4.1 1.9 2 0 0 2 2 2 1 Zinc finger-containing protein DUF3450 PF11932.8 KLO07325.1 - 0.07 12.4 5.8 0.1 11.9 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KLO07325.1 - 0.17 12.4 7.2 0.28 11.7 7.2 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region AT_hook PF02178.19 KLO07325.1 - 2.2 8.4 8.1 5.7 7.2 8.1 1.7 1 0 0 1 1 1 0 AT hook motif F-box-like PF12937.7 KLO07326.1 - 8e-07 28.9 1.1 2.8e-06 27.1 1.1 2.0 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO07326.1 - 0.024 15.1 6.9 9.1 6.9 0.4 4.8 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) PLDc_2 PF13091.6 KLO07327.1 - 3.9e-13 49.4 0.0 2e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KLO07327.1 - 4.4e-10 39.3 0.1 0.00044 20.3 0.3 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif zf-C3HC4_3 PF13920.6 KLO07328.1 - 5.8e-10 38.9 16.1 5.8e-10 38.9 16.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO07328.1 - 0.013 15.3 14.9 0.028 14.3 14.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MYND PF01753.18 KLO07329.1 - 4.3e-08 33.1 13.9 6.9e-08 32.5 13.9 1.3 1 0 0 1 1 1 1 MYND finger DUF1035 PF06281.12 KLO07329.1 - 0.16 12.0 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) zf-Mss51 PF13824.6 KLO07329.1 - 1.4 9.1 7.0 2.6 8.2 7.0 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PWWP PF00855.17 KLO07330.1 - 0.062 13.7 1.1 14 6.1 0.0 2.8 3 0 0 3 3 3 0 PWWP domain GDA1_CD39 PF01150.17 KLO07331.1 - 5e-111 371.4 0.0 3.7e-110 368.5 0.0 1.9 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KLO07331.1 - 0.04 13.4 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Fungal_trans PF04082.18 KLO07333.1 - 4.2e-16 58.8 0.1 8e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO07333.1 - 9e-05 22.5 9.2 0.00021 21.4 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KLO07335.1 - 3.9e-06 27.0 1.0 0.0078 16.6 0.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO07335.1 - 1.2e-05 25.7 1.4 0.017 15.9 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KLO07335.1 - 0.0004 20.6 0.7 0.09 13.1 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KLO07335.1 - 0.085 12.9 1.1 4.7 7.3 0.0 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 KLO07335.1 - 0.11 12.8 1.8 0.61 10.4 1.8 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Ima1_N PF09779.9 KLO07335.1 - 0.13 13.1 0.8 0.28 12.0 0.1 1.8 2 0 0 2 2 2 0 Ima1 N-terminal domain WD40 PF00400.32 KLO07336.1 - 2.3e-42 142.1 25.4 1.7e-06 28.6 0.1 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KLO07336.1 - 3.2e-12 46.1 0.4 3.2e-12 46.1 0.4 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO07336.1 - 6.8e-10 38.6 2.5 8.9e-10 38.2 0.4 2.2 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KLO07336.1 - 1.1e-07 32.0 0.3 5.1 7.5 0.1 5.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KLO07336.1 - 1.8e-07 30.2 7.0 0.0035 16.1 0.2 5.3 5 1 0 6 6 6 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KLO07336.1 - 0.016 14.8 2.0 1.2 8.7 0.2 3.0 2 1 1 3 3 3 0 PQQ-like domain PALB2_WD40 PF16756.5 KLO07336.1 - 0.059 12.3 2.5 13 4.6 0.2 4.0 2 2 3 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Pro_isomerase PF00160.21 KLO07337.1 - 4.5e-52 176.5 0.1 5.1e-52 176.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tim54 PF11711.8 KLO07338.1 - 2.7e-58 197.6 0.0 4.8e-58 196.7 0.0 1.3 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Sec63 PF02889.16 KLO07339.1 - 3.3e-28 98.6 0.0 6.2e-28 97.7 0.0 1.4 1 1 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KLO07339.1 - 6.2e-24 84.7 0.0 1.9e-23 83.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO07339.1 - 9.8e-11 41.9 0.0 3.4e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KLO07339.1 - 4.2e-10 40.0 0.0 5.2e-09 36.4 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KLO07339.1 - 0.00044 20.6 0.1 0.0025 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KLO07339.1 - 0.062 13.6 0.1 0.33 11.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain ExoD PF06055.12 KLO07339.1 - 0.068 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD ComA PF02679.15 KLO07339.1 - 0.097 12.1 0.1 10 5.5 0.0 2.3 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) DUF4332 PF14229.6 KLO07339.1 - 0.14 12.4 0.3 1 9.6 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4332) Tyr_Deacylase PF02580.16 KLO07340.1 - 3e-41 141.3 0.0 3.5e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF2848 PF11010.8 KLO07340.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) AIRC PF00731.20 KLO07341.1 - 1.1e-63 213.2 0.6 2.6e-63 212.0 0.6 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KLO07341.1 - 3.2e-56 189.6 0.0 5.7e-56 188.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KLO07341.1 - 1.4e-18 66.3 1.6 1.6e-18 66.2 0.3 1.8 2 0 0 2 2 2 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KLO07341.1 - 0.0082 15.7 0.0 0.02 14.4 0.0 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.19 KLO07341.1 - 0.025 13.9 0.1 0.059 12.7 0.1 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KLO07341.1 - 0.032 14.1 0.1 0.076 12.9 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KLO07341.1 - 0.052 12.8 0.3 0.052 12.8 0.3 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PrpR_N PF06506.11 KLO07341.1 - 0.088 12.4 0.3 0.4 10.2 0.0 2.2 3 0 0 3 3 3 0 Propionate catabolism activator Dala_Dala_lig_C PF07478.13 KLO07341.1 - 0.093 12.3 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus XdhC_C PF13478.6 KLO07341.1 - 0.098 13.2 0.1 0.58 10.7 0.0 2.3 2 1 0 2 2 2 0 XdhC Rossmann domain CoA_binding_2 PF13380.6 KLO07341.1 - 0.14 12.7 0.4 28 5.2 0.0 2.9 2 1 1 3 3 3 0 CoA binding domain E1-E2_ATPase PF00122.20 KLO07342.1 - 6.7e-41 139.8 2.3 6.7e-41 139.8 2.3 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KLO07342.1 - 6.6e-39 133.5 3.1 6.6e-39 133.5 3.1 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KLO07342.1 - 1.2e-24 87.8 0.7 4.4e-12 46.7 0.1 3.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KLO07342.1 - 5.6e-17 61.6 0.0 9.8e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KLO07342.1 - 1.3e-10 40.8 0.0 1.1e-09 37.9 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KLO07342.1 - 2.1e-07 30.9 0.6 2.4e-06 27.5 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KLO07342.1 - 0.0072 16.8 0.0 0.14 12.5 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 KLO07342.1 - 0.45 10.3 11.7 0.35 10.7 0.1 3.6 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) DUF1772 PF08592.11 KLO07342.1 - 6.2 7.1 9.6 5.1 7.4 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DctQ PF04290.12 KLO07342.1 - 8.9 6.2 21.0 3.1 7.7 3.6 4.3 4 0 0 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component Npa1 PF11707.8 KLO07343.1 - 1.2e-91 307.6 0.2 1.2e-91 307.6 0.2 2.6 4 0 0 4 4 4 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KLO07343.1 - 1.7e-54 184.5 3.5 7.1e-54 182.4 3.5 2.2 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 HEAT_EZ PF13513.6 KLO07343.1 - 0.003 18.0 0.7 3.7 8.1 0.0 4.3 3 0 0 3 3 3 1 HEAT-like repeat MMS19_N PF14500.6 KLO07343.1 - 0.0063 16.1 2.1 0.77 9.3 0.0 2.9 2 0 0 2 2 2 2 Dos2-interacting transcription regulator of RNA-Pol-II ERAP1_C PF11838.8 KLO07343.1 - 0.03 13.9 1.4 0.21 11.1 0.0 3.1 2 0 0 2 2 2 0 ERAP1-like C-terminal domain Creb_binding PF09030.10 KLO07343.1 - 0.1 13.3 0.0 0.4 11.4 0.0 2.0 1 0 0 1 1 1 0 Creb binding Proteasome PF00227.26 KLO07344.1 - 2.8e-32 111.7 0.0 8.9e-32 110.1 0.0 1.6 1 1 0 1 1 1 1 Proteasome subunit Uteroglobin PF01099.17 KLO07344.1 - 0.038 14.3 0.0 0.066 13.6 0.0 1.4 1 0 0 1 1 1 0 Uteroglobin family L6_membrane PF05805.12 KLO07347.1 - 0.63 9.6 5.4 0.93 9.0 1.6 2.4 2 0 0 2 2 2 0 L6 membrane protein Ldh_1_C PF02866.18 KLO07348.1 - 2.4e-48 164.3 0.0 6.7e-48 162.8 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KLO07348.1 - 1.5e-44 151.5 0.0 2.2e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KLO07348.1 - 0.0009 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KLO07348.1 - 0.033 14.6 0.1 0.28 11.7 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 KLO07348.1 - 0.11 12.1 0.0 1.8 8.1 0.0 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Amidohydro_1 PF01979.20 KLO07349.1 - 4.9e-37 128.0 0.0 5.8e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KLO07349.1 - 2.1e-12 47.3 0.1 4.9e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family CLP1_P PF16575.5 KLO07350.1 - 2.1e-42 145.0 0.0 3.3e-41 141.1 0.0 2.1 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop tRNA_bind_3 PF17176.4 KLO07350.1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 tRNA-binding domain AAA_16 PF13191.6 KLO07350.1 - 0.029 14.8 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KLO07350.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KLO07350.1 - 0.21 11.6 0.0 0.59 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Trehalose_recp PF06151.13 KLO07352.1 - 0.014 14.1 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Trehalose receptor Retrotrans_gag PF03732.17 KLO07352.1 - 0.11 12.7 0.1 0.44 10.8 0.0 1.8 1 1 1 2 2 2 0 Retrotransposon gag protein RVP_2 PF08284.11 KLO07353.1 - 4.8e-05 23.1 0.1 8.1e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KLO07353.1 - 0.00076 20.0 0.1 0.0012 19.4 0.1 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KLO07353.1 - 0.015 15.9 0.1 0.031 14.9 0.1 1.5 1 1 0 1 1 1 0 Aspartyl protease LpxC PF03331.13 KLO07358.1 - 0.18 11.3 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase Pet191_N PF10203.9 KLO07361.1 - 0.036 14.3 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Abi_HHR PF07815.14 KLO07363.1 - 0.17 12.0 0.0 43 4.3 0.0 3.3 3 0 0 3 3 3 0 Abl-interactor HHR DUF3035 PF11233.8 KLO07364.1 - 0.078 13.3 4.5 0.17 12.2 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3035) Acyl_transf_1 PF00698.21 KLO07365.1 - 0.012 15.2 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 Acyl transferase domain DUF3176 PF11374.8 KLO07366.1 - 0.63 10.3 16.0 0.049 13.8 1.4 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3176) DUF3325 PF11804.8 KLO07366.1 - 2.3 8.4 10.7 0.35 11.0 0.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) DUF3176 PF11374.8 KLO07367.1 - 0.0039 17.4 7.4 0.28 11.4 0.6 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3176) RNB PF00773.19 KLO07368.1 - 1.5e-94 317.0 0.0 2.1e-94 316.5 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 KLO07368.1 - 3.5e-27 94.9 0.0 8.1e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KLO07368.1 - 5.4e-24 84.0 3.1 1.3e-23 82.8 3.1 1.7 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 KLO07368.1 - 1.1e-14 54.2 0.0 7.5e-14 51.5 0.0 2.5 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KLO07368.1 - 3e-10 40.1 3.7 0.00042 20.4 0.0 4.8 5 0 0 5 5 5 3 Cold shock domain PIN_4 PF13638.6 KLO07368.1 - 3.6e-08 33.8 0.0 8.3e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.11 KLO07368.1 - 0.01 15.5 2.7 0.13 11.9 0.1 2.8 2 0 0 2 2 2 0 Ribonuclease B OB domain His_Phos_2 PF00328.22 KLO07369.1 - 1.1e-11 44.7 0.0 1.6e-10 40.9 0.0 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3176 PF11374.8 KLO07370.1 - 1.2 9.4 8.4 13 6.0 1.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) DUF3176 PF11374.8 KLO07371.1 - 0.19 11.9 3.3 0.15 12.2 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Aldo_ket_red PF00248.21 KLO07372.1 - 5.3e-67 226.1 0.1 6e-67 225.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KLO07373.1 - 1.2e-69 234.8 0.2 1.3e-69 234.6 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AsnA PF03590.15 KLO07373.1 - 0.022 14.5 0.2 0.036 13.8 0.2 1.3 1 0 0 1 1 1 0 Aspartate-ammonia ligase Aldo_ket_red PF00248.21 KLO07374.1 - 1.3e-67 228.1 0.1 1.5e-67 227.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RNA_binding PF01877.17 KLO07374.1 - 0.15 12.4 0.2 0.56 10.5 0.1 2.0 2 0 0 2 2 2 0 RNA binding F-box-like PF12937.7 KLO07375.1 - 3e-05 23.8 0.0 0.0001 22.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like LpqV PF17301.2 KLO07376.1 - 0.06 13.6 0.7 0.12 12.7 0.7 1.4 1 0 0 1 1 1 0 Putative lipoprotein LpqV DUF3602 PF12223.8 KLO07377.1 - 5.1e-29 100.7 33.9 3.2e-09 37.3 8.9 4.3 1 1 1 4 4 4 4 Protein of unknown function (DUF3602) Spot_14 PF07084.12 KLO07377.1 - 0.25 11.5 0.7 7.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 F-box-like PF12937.7 KLO07378.1 - 0.0024 17.7 0.0 0.0063 16.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF72 PF01904.18 KLO07378.1 - 0.047 13.8 0.1 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF72 F-box-like PF12937.7 KLO07379.1 - 5.7e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF1866 PF08952.11 KLO07380.1 - 0.14 12.0 0.0 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) COQ7 PF03232.13 KLO07382.1 - 1.9e-67 226.3 0.8 2.2e-67 226.1 0.8 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 GARP PF16731.5 KLO07382.1 - 0.001 18.8 0.1 0.0013 18.4 0.1 1.2 1 0 0 1 1 1 1 Glutamic acid/alanine-rich protein of Trypanosoma RAC_head PF16717.5 KLO07382.1 - 0.037 15.0 0.2 0.13 13.2 0.2 1.9 1 1 0 1 1 1 0 Ribosome-associated complex head domain NDUF_B4 PF07225.12 KLO07383.1 - 3.1e-05 23.8 0.1 3.1e-05 23.8 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) G-patch PF01585.23 KLO07384.1 - 4.6e-14 52.0 1.7 4.6e-14 52.0 1.7 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KLO07384.1 - 5.8e-06 26.3 1.3 3e-05 24.0 1.3 2.3 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KLO07384.1 - 1e-05 25.2 1.4 0.037 13.9 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.13 KLO07384.1 - 0.0043 16.7 1.4 0.012 15.2 1.4 1.8 1 0 0 1 1 1 1 RED-like protein N-terminal region zf-C2H2_jaz PF12171.8 KLO07384.1 - 0.018 15.3 1.5 0.039 14.2 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KLO07384.1 - 0.055 13.8 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KLO07384.1 - 0.098 13.6 0.6 0.23 12.4 0.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO07384.1 - 0.12 12.8 0.6 0.3 11.6 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type PBP PF01161.20 KLO07385.1 - 5.5e-14 52.6 0.0 8.2e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pkinase PF00069.25 KLO07386.1 - 2.3e-64 217.3 0.0 2.7e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO07386.1 - 2.6e-24 85.9 0.0 3.8e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO07386.1 - 7.8e-05 22.1 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO07386.1 - 0.0043 17.0 0.3 0.025 14.5 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KLO07386.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 KLO07386.1 - 0.051 13.2 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KLO07386.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 KLO07387.1 - 3.4e-45 151.1 23.0 5.9e-08 33.3 0.1 9.2 8 1 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.8 KLO07387.1 - 3.9e-13 48.9 5.2 0.039 12.6 0.1 5.7 3 2 2 6 6 6 5 Nucleoporin Nup120/160 F-box-like PF12937.7 KLO07387.1 - 1.6e-10 40.7 0.0 3.1e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO07387.1 - 2.6e-07 30.3 0.0 6e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KLO07387.1 - 4e-06 27.0 1.4 2 8.7 0.0 5.4 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KLO07387.1 - 0.0013 18.7 0.1 8.6 6.4 0.0 5.2 4 2 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region F-box_4 PF15966.5 KLO07387.1 - 0.007 16.2 0.0 0.046 13.6 0.0 2.3 1 1 1 2 2 2 1 F-box PALB2_WD40 PF16756.5 KLO07387.1 - 1.6 7.5 3.7 47 2.7 0.0 3.9 4 1 0 5 5 5 0 Partner and localizer of BRCA2 WD40 domain FH2 PF02181.23 KLO07388.1 - 4e-73 246.7 5.6 4e-73 246.7 5.6 2.5 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KLO07388.1 - 5e-36 124.0 0.0 5e-36 124.0 0.0 2.7 3 1 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KLO07388.1 - 1.6e-32 112.7 1.1 4.5e-32 111.2 1.1 1.8 1 0 0 1 1 1 1 Diaphanous FH3 Domain Med9 PF07544.13 KLO07388.1 - 0.01 15.9 2.1 0.01 15.9 2.1 3.3 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SPOUT_MTase_2 PF14419.6 KLO07388.1 - 0.037 13.4 2.8 0.038 13.4 0.5 2.1 2 0 0 2 2 2 0 AF2226-like SPOUT RNA Methylase fused to THUMP Gp-FAR-1 PF05823.12 KLO07388.1 - 0.42 11.0 6.4 3.4 8.0 1.1 3.3 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1664 PF07889.12 KLO07388.1 - 3.9 7.5 8.0 4.5 7.3 1.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) JUPITER PF17054.5 KLO07389.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Hid1 PF12722.7 KLO07390.1 - 5.4e-180 600.4 0.0 6.6e-180 600.1 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KLO07390.1 - 1.5e-94 317.6 0.1 1.9e-94 317.3 0.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Copper-bind PF00127.20 KLO07391.1 - 0.00016 22.1 0.1 0.00035 21.0 0.1 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Rad51 PF08423.11 KLO07392.1 - 1.4e-38 132.6 0.0 2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 KLO07392.1 - 2e-06 27.3 0.2 3e-05 23.5 0.2 2.1 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KLO07392.1 - 6.1e-05 22.5 0.1 0.038 13.3 0.1 2.2 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA_25 PF13481.6 KLO07392.1 - 0.00042 20.0 0.0 0.001 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 KLO07392.1 - 0.00048 19.7 0.2 0.046 13.2 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein Atg8 PF02991.16 KLO07393.1 - 2.8e-51 172.1 0.3 3.2e-51 171.8 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KLO07393.1 - 3.8e-08 33.6 0.0 4.8e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Pkinase_Tyr PF07714.17 KLO07394.1 - 3.3e-45 154.4 0.0 6.2e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO07394.1 - 8e-37 127.0 0.0 1.6e-36 126.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.19 KLO07394.1 - 5e-32 111.5 0.0 1.1e-31 110.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain Kinase-like PF14531.6 KLO07394.1 - 0.002 17.5 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO07394.1 - 0.0097 15.9 0.2 0.28 11.1 0.2 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO07394.1 - 0.021 13.6 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KLO07394.1 - 0.072 12.4 0.8 0.25 10.7 0.0 2.2 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO07394.1 - 0.1 12.2 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 RIO1 family FA_hydroxylase PF04116.13 KLO07398.1 - 4.7e-22 78.8 19.1 4.7e-22 78.8 19.1 1.7 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Phi29_Phage_SSB PF17427.2 KLO07399.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Phage Single-stranded DNA-binding protein Methyltransf_2 PF00891.18 KLO07400.1 - 8e-25 87.4 0.0 8.7e-24 84.0 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KLO07400.1 - 0.0061 17.3 0.0 0.018 15.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO07400.1 - 0.0082 16.8 0.0 0.03 15.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Dimerisation PF08100.11 KLO07400.1 - 0.018 15.0 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Corona_NS3b PF03053.14 KLO07401.1 - 0.0002 21.2 0.7 0.00032 20.5 0.7 1.3 1 0 0 1 1 1 1 ORF3b coronavirus protein FUSC_2 PF13515.6 KLO07401.1 - 0.02 15.0 1.9 0.02 15.0 1.9 2.4 2 1 1 3 3 3 0 Fusaric acid resistance protein-like Na_Ca_ex PF01699.24 KLO07404.1 - 1.1e-13 51.4 27.7 1.1e-08 35.1 10.5 3.1 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Vac7 PF12751.7 KLO07404.1 - 0.49 9.8 4.6 0.81 9.1 4.6 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Acyltransferase PF01553.21 KLO07405.1 - 1.6e-23 82.8 0.0 2.1e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase ADH_zinc_N PF00107.26 KLO07406.1 - 3.2e-18 66.0 0.0 5.5e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO07406.1 - 7.6e-10 40.0 0.0 1.2e-09 39.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO07406.1 - 3.6e-09 36.5 0.0 5.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KLO07406.1 - 6.2e-07 29.1 0.1 1e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus DS PF01916.17 KLO07406.1 - 0.088 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase DUF2385 PF09539.10 KLO07407.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) PhyH PF05721.13 KLO07408.1 - 1.1e-15 58.5 0.1 1.7e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Xan_ur_permease PF00860.20 KLO07409.1 - 3.1e-30 105.2 26.9 1.1e-18 67.1 10.7 2.3 3 0 0 3 3 3 2 Permease family Sulfate_transp PF00916.20 KLO07409.1 - 4.7e-05 22.3 3.0 4.7e-05 22.3 3.0 2.7 2 1 0 2 2 2 2 Sulfate permease family MFS_MOT1 PF16983.5 KLO07409.1 - 0.0053 17.2 3.9 0.0053 17.2 3.9 2.7 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily F-box-like PF12937.7 KLO07410.1 - 3.6e-05 23.6 0.1 0.00011 22.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO07411.1 - 0.0013 18.6 0.3 0.0098 15.8 0.1 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO07411.1 - 0.038 14.4 10.6 7.8 7.1 0.1 5.0 3 1 3 6 6 6 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KLO07411.1 - 1.1 9.3 6.9 0.32 10.9 0.5 3.2 3 0 0 3 3 3 0 F-box domain LRR_8 PF13855.6 KLO07411.1 - 2 8.2 11.4 3.8 7.3 0.6 4.5 4 1 0 4 4 4 0 Leucine rich repeat TF_Zn_Ribbon PF08271.12 KLO07412.1 - 0.019 14.5 3.7 0.026 14.1 0.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding TerY_C PF15616.6 KLO07412.1 - 0.041 14.0 0.9 0.33 11.1 0.3 2.1 2 0 0 2 2 2 0 TerY-C metal binding domain zf-C2H2 PF00096.26 KLO07413.1 - 1.2e-29 101.0 71.0 0.0031 17.9 1.0 10.5 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO07413.1 - 2.6e-18 65.1 66.1 0.0058 17.4 1.3 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KLO07413.1 - 7.1e-11 42.3 31.6 0.00017 21.8 3.9 5.9 3 1 3 6 6 6 4 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 KLO07413.1 - 4e-10 39.7 70.5 1.2e-06 28.7 0.4 11.9 13 0 0 13 13 13 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KLO07413.1 - 2.8e-09 37.0 31.7 0.14 12.4 0.3 8.6 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KLO07413.1 - 0.0019 18.4 27.0 0.025 14.7 1.1 5.6 4 1 3 7 7 7 2 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KLO07413.1 - 0.0085 16.1 35.1 0.52 10.4 0.2 8.4 8 1 0 8 8 8 2 C2H2-type zinc finger zf-met PF12874.7 KLO07413.1 - 0.02 15.3 28.1 7.1 7.2 1.4 8.6 9 0 0 9 9 9 0 Zinc-finger of C2H2 type GAGA PF09237.11 KLO07413.1 - 2.1 8.2 7.3 6.8 6.6 0.1 3.9 3 1 1 4 4 4 0 GAGA factor Transpos_assoc PF13963.6 KLO07413.1 - 2.9 8.3 25.6 1.2 9.4 0.1 6.1 4 2 2 6 6 6 0 Transposase-associated domain FYDLN_acid PF09538.10 KLO07413.1 - 7.8 7.2 12.6 12 6.6 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (FYDLN_acid) AA_permease_2 PF13520.6 KLO07414.1 - 4.1e-41 141.2 56.2 5.6e-41 140.8 56.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KLO07414.1 - 1.3e-24 86.7 44.1 1.6e-24 86.4 44.1 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M24 PF00557.24 KLO07415.1 - 9.3e-57 192.1 0.0 1.2e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KLO07415.1 - 6.7e-39 132.4 0.0 1.2e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain WLM PF08325.10 KLO07416.1 - 5.9e-42 143.9 0.1 1.1e-41 143.0 0.1 1.4 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.23 KLO07416.1 - 5.4e-10 38.9 0.1 1.1e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 KLO07416.1 - 9.3e-06 25.5 0.3 2.6e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD PF11976.8 KLO07416.1 - 0.0064 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF45 PF01863.17 KLO07416.1 - 0.12 12.4 1.0 0.5 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF45 DNA_pol_delta_4 PF04081.13 KLO07417.1 - 6.2e-30 104.2 0.3 1.1e-29 103.5 0.3 1.5 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF4551 PF15087.6 KLO07417.1 - 3.8 6.2 6.4 5.1 5.8 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) p450 PF00067.22 KLO07419.1 - 3.7e-36 124.8 0.0 1.7e-35 122.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 TRP PF06011.12 KLO07420.1 - 0.00047 19.0 0.1 0.00056 18.7 0.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel BatD PF13584.6 KLO07420.1 - 0.037 12.9 0.1 0.048 12.5 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance STT3 PF02516.14 KLO07421.1 - 1e-139 466.6 35.9 8.7e-133 443.8 32.2 2.5 1 1 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Ribonuc_P_40 PF08584.11 KLO07422.1 - 8.5e-29 100.7 0.1 1.3e-28 100.1 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit RuvX PF03652.15 KLO07422.1 - 0.19 12.1 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction resolvase Pantoate_ligase PF02569.15 KLO07423.1 - 1.1e-91 306.7 0.0 1.3e-91 306.5 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase UCH PF00443.29 KLO07424.1 - 1.2e-64 218.3 0.0 1.8e-64 217.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KLO07424.1 - 2.8e-20 73.2 0.0 1.9e-16 60.6 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KLO07424.1 - 5.1e-06 27.0 0.0 1.2e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.20 KLO07424.1 - 0.0023 17.6 0.2 0.0045 16.7 0.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-HC5HC2H_2 PF13832.6 KLO07425.1 - 1e-14 54.6 15.7 7.5e-13 48.6 1.2 4.1 3 0 0 3 3 3 2 PHD-zinc-finger like domain BAH PF01426.18 KLO07425.1 - 1.6e-14 53.8 0.0 2.9e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KLO07425.1 - 1.4e-09 37.7 50.2 4.7e-07 29.6 10.7 6.2 6 0 0 6 6 6 3 PHD-finger zf-HC5HC2H PF13771.6 KLO07425.1 - 3.4e-08 33.6 2.2 3.4e-08 33.6 2.2 4.7 4 1 0 4 4 4 2 PHD-like zinc-binding domain GATA PF00320.27 KLO07425.1 - 7.1e-05 22.3 3.3 7.1e-05 22.3 3.3 4.6 4 0 0 4 4 4 1 GATA zinc finger PHD_2 PF13831.6 KLO07425.1 - 0.0074 15.8 1.9 0.0074 15.8 1.9 5.5 6 0 0 6 6 6 2 PHD-finger zinc_ribbon_6 PF14599.6 KLO07425.1 - 0.074 13.1 0.2 0.074 13.1 0.2 4.2 5 0 0 5 5 5 0 Zinc-ribbon SET PF00856.28 KLO07426.1 - 2.5e-11 44.3 0.0 1.5e-10 41.7 0.0 2.1 1 1 0 1 1 1 1 SET domain DUF4592 PF15262.6 KLO07426.1 - 0.98 10.1 7.1 0.3 11.8 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4592) CAP_GLY PF01302.25 KLO07427.1 - 1.2e-24 86.0 3.7 2.7e-24 84.9 2.5 2.0 2 0 0 2 2 2 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KLO07427.1 - 7.1e-20 71.3 0.0 1.9e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 KLO07427.1 - 0.0065 16.2 0.0 0.39 10.5 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin family HoxA13_N PF12284.8 KLO07427.1 - 0.62 10.7 3.1 7.4 7.2 0.2 2.5 3 0 0 3 3 3 0 Hox protein A13 N terminal Lipase_3 PF01764.25 KLO07428.1 - 4.2e-19 68.8 0.0 5.7e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KLO07428.1 - 0.025 15.2 0.1 0.031 14.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KLO07428.1 - 0.055 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 KLO07429.1 - 2.8e-21 75.9 0.0 3.8e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Esterase_phd PF10503.9 KLO07429.1 - 0.0087 15.6 0.9 0.013 15.0 0.9 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KLO07429.1 - 0.01 16.5 0.1 0.013 16.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fer4_6 PF12837.7 KLO07431.1 - 0.072 13.2 0.9 0.11 12.6 0.9 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_3 PF12798.7 KLO07431.1 - 0.16 13.0 2.2 0.24 12.4 2.2 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Exo_endo_phos PF03372.23 KLO07432.1 - 1.3e-11 44.5 0.0 5.9e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KLO07432.1 - 1.6e-06 28.1 2.8 0.00024 21.1 0.7 2.6 2 0 0 2 2 2 2 GRF zinc finger Exo_endo_phos_2 PF14529.6 KLO07432.1 - 0.05 13.4 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Thymidylate_kin PF02223.17 KLO07433.1 - 5.4e-47 159.9 0.0 6.1e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase CotJB PF12652.7 KLO07433.1 - 0.002 18.3 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 CotJB protein KTI12 PF08433.10 KLO07433.1 - 0.0033 16.9 0.0 0.01 15.3 0.0 1.7 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 KLO07433.1 - 0.015 15.6 0.0 0.025 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KLO07433.1 - 0.056 14.0 0.0 0.11 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KLO07433.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase PRK PF00485.18 KLO07433.1 - 0.09 12.5 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family zf-C2H2_11 PF16622.5 KLO07437.1 - 0.00093 18.9 4.0 0.0017 18.1 4.0 1.4 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-met PF12874.7 KLO07437.1 - 0.0037 17.6 1.6 0.013 15.8 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KLO07437.1 - 0.027 14.5 0.3 0.068 13.2 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KLO07437.1 - 0.11 13.4 2.0 0.24 12.4 1.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KLO07437.1 - 0.11 12.8 0.7 0.21 11.9 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KLO07437.1 - 0.12 12.9 2.4 0.27 11.8 0.8 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Macoilin PF09726.9 KLO07437.1 - 9.7 4.6 11.5 14 4.0 11.5 1.2 1 0 0 1 1 1 0 Macoilin family MKT1_C PF12246.8 KLO07438.1 - 1.6e-72 243.6 0.0 3.3e-72 242.6 0.0 1.5 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KLO07438.1 - 7.1e-26 90.4 0.0 1.6e-25 89.3 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KLO07438.1 - 1.1e-07 32.2 0.0 3.8e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KLO07438.1 - 0.078 13.3 0.0 0.25 11.7 0.0 1.9 1 1 0 1 1 1 0 XPG I-region F-box-like PF12937.7 KLO07440.1 - 0.00049 19.9 1.7 0.0021 17.9 0.1 2.9 3 0 0 3 3 3 1 F-box-like tRNA-synt_2b PF00587.25 KLO07441.1 - 5.1e-33 114.5 0.0 8.3e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KLO07441.1 - 7.8e-19 67.6 1.4 8.1e-19 67.6 0.1 1.7 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.21 KLO07441.1 - 2.7e-10 40.2 0.0 6.2e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KLO07441.1 - 3.3e-07 30.3 0.0 6.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Thymidylate_kin PF02223.17 KLO07443.1 - 3.6e-47 160.4 0.0 4.3e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 KLO07443.1 - 0.0039 16.7 0.0 0.012 15.1 0.0 1.7 2 1 0 2 2 2 1 Chromatin associated protein KTI12 CotJB PF12652.7 KLO07443.1 - 0.017 15.4 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 CotJB protein AAA_28 PF13521.6 KLO07443.1 - 0.023 14.9 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KLO07443.1 - 0.051 13.5 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KLO07443.1 - 0.069 13.7 0.0 0.12 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 KLO07443.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family UQ_con PF00179.26 KLO07444.1 - 1.2e-18 67.1 0.0 1.8e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pro_isomerase PF00160.21 KLO07445.1 - 5.8e-40 137.1 0.1 2e-39 135.4 0.0 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SlyX PF04102.12 KLO07445.1 - 3.2 8.4 8.2 0.14 12.8 1.5 2.2 2 0 0 2 2 2 0 SlyX AbiTii PF18864.1 KLO07446.1 - 0.043 14.0 0.3 1.7 8.7 0.2 2.2 2 0 0 2 2 2 0 AbiTii Med2 PF11214.8 KLO07446.1 - 1.7 8.8 4.9 1.3 9.3 2.5 2.0 2 0 0 2 2 2 0 Mediator complex subunit 2 PX PF00787.24 KLO07446.1 - 2.8 8.0 6.2 4.7 7.2 3.7 2.3 1 1 1 2 2 2 0 PX domain Seryl_tRNA_N PF02403.22 KLO07446.1 - 7.4 6.8 7.7 14 6.0 0.0 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PDDEXK_1 PF12705.7 KLO07447.1 - 0.033 14.1 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF2999 PF11212.8 KLO07447.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) DUF3387 PF11867.8 KLO07447.1 - 0.25 10.7 0.0 0.36 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) VPS9 PF02204.18 KLO07449.1 - 9.3e-18 64.4 0.0 8.4e-17 61.3 0.0 2.2 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PBD PF00786.28 KLO07451.1 - 1.1e-23 83.3 0.1 1.6e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase PF00069.25 KLO07452.1 - 1.7e-69 234.1 0.0 2.3e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO07452.1 - 2.1e-47 161.6 0.0 3.3e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO07452.1 - 4.5e-06 25.7 0.0 5.9e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO07452.1 - 0.00026 20.4 0.0 0.00041 19.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO07452.1 - 0.0016 17.8 0.1 0.009 15.4 0.0 1.9 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO07452.1 - 0.0066 16.4 0.3 0.12 12.3 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DSHCT PF08148.12 KLO07452.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain Ndc1_Nup PF09531.10 KLO07452.1 - 5 5.7 4.6 6 5.4 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PI3_PI4_kinase PF00454.27 KLO07453.1 - 9.8e-54 182.8 0.0 1.6e-53 182.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KLO07453.1 - 5.5e-35 120.7 0.0 3.5e-34 118.1 0.0 2.5 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KLO07453.1 - 2e-12 46.7 0.0 1.3e-11 44.1 0.0 2.3 2 0 0 2 2 2 1 FATC domain HEAT PF02985.22 KLO07453.1 - 0.018 15.2 0.2 4.2 7.9 0.0 4.0 2 0 0 2 2 2 0 HEAT repeat Peptidase_S10 PF00450.22 KLO07454.1 - 1.9e-66 225.3 0.0 1.3e-65 222.5 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KLO07454.1 - 0.011 15.0 0.0 0.22 10.7 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S10 PF00450.22 KLO07455.1 - 2.5e-65 221.5 0.0 6.7e-65 220.1 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase RT_RNaseH_2 PF17919.1 KLO07455.1 - 0.014 15.4 0.1 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Peptidase_M20 PF01546.28 KLO07456.1 - 3.3e-10 40.0 0.2 4.9e-10 39.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KLO07456.1 - 5.7e-09 35.9 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain GPW_gp25 PF04965.14 KLO07456.1 - 0.035 13.9 0.0 0.095 12.5 0.0 1.7 1 0 0 1 1 1 0 Gene 25-like lysozyme Glyco_hydro_14 PF01373.17 KLO07456.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 SUI1 PF01253.22 KLO07457.1 - 1.3e-21 76.9 1.2 3.1e-21 75.7 1.2 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 DDHD PF02862.17 KLO07457.1 - 9.1 6.4 9.2 0.3 11.2 2.6 1.8 1 1 1 2 2 2 0 DDHD domain Pkinase PF00069.25 KLO07459.1 - 2.4e-42 145.1 0.0 3.1e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO07459.1 - 8.4e-39 133.4 0.0 1.1e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO07459.1 - 0.00074 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Carn_acyltransf PF00755.20 KLO07461.1 - 8.9e-181 602.5 0.0 1e-180 602.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SURF6 PF04935.12 KLO07461.1 - 0.049 13.4 0.5 0.1 12.4 0.5 1.4 1 0 0 1 1 1 0 Surfeit locus protein 6 Marek_SORF3 PF07153.11 KLO07461.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein Abhydrolase_3 PF07859.13 KLO07463.1 - 1.4e-15 57.8 0.1 2.4e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KLO07463.1 - 3.7e-05 23.3 0.0 0.26 10.8 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KLO07463.1 - 0.00037 19.5 0.0 0.047 12.5 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Chlorophyllase2 PF12740.7 KLO07463.1 - 0.00044 19.2 0.0 0.00066 18.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.9 KLO07463.1 - 0.044 13.3 0.0 0.48 9.9 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase Chlorophyllase PF07224.11 KLO07463.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Melibiase_C PF17801.1 KLO07464.1 - 0.052 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Alpha galactosidase C-terminal beta sandwich domain Sugar_tr PF00083.24 KLO07465.1 - 2.3e-49 168.5 13.5 6.5e-49 167.0 13.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO07465.1 - 2.8e-22 79.2 16.9 9.3e-21 74.1 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Usher PF00577.20 KLO07465.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Outer membrane usher protein SET PF00856.28 KLO07467.1 - 1.7e-08 35.1 0.0 6.2e-08 33.2 0.0 2.1 2 1 0 2 2 2 1 SET domain SET PF00856.28 KLO07468.1 - 2.4e-09 37.8 0.0 2.3e-08 34.6 0.0 2.7 3 1 0 3 3 3 1 SET domain YtxH PF12732.7 KLO07468.1 - 6.4 7.4 6.5 3.6 8.2 2.2 2.5 2 0 0 2 2 2 0 YtxH-like protein SET PF00856.28 KLO07469.1 - 4.2e-10 40.3 0.0 2.1e-09 38.0 0.0 2.2 1 1 0 1 1 1 1 SET domain IATP PF04568.12 KLO07471.1 - 0.24 11.8 2.9 0.16 12.4 0.4 1.9 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP SET PF00856.28 KLO07472.1 - 9.8e-06 26.1 0.0 3.9e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 SET domain SET PF00856.28 KLO07473.1 - 1e-08 35.8 0.0 4.7e-08 33.6 0.0 2.2 2 1 0 2 2 2 1 SET domain SET PF00856.28 KLO07474.1 - 2e-09 38.0 0.0 1.3e-08 35.5 0.0 2.4 2 1 0 2 2 2 1 SET domain DUF5127 PF17168.4 KLO07475.1 - 6.1e-56 189.7 0.5 9.7e-55 185.8 0.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO07475.1 - 1.4e-43 148.5 0.9 2.4e-43 147.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO07475.1 - 3.7e-25 89.3 0.0 7e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid6H PF17389.2 KLO07475.1 - 0.0011 18.3 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_52 PF03512.13 KLO07475.1 - 0.0031 16.5 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 52 Plavaka PF18759.1 KLO07476.1 - 2.7e-08 33.4 0.1 4.7e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Plavaka transposase DUF3583 PF12126.8 KLO07476.1 - 0.073 12.5 2.3 0.14 11.6 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) ox_reductase_C PF08635.10 KLO07476.1 - 0.093 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain BolA PF01722.18 KLO07478.1 - 3.4e-12 46.4 0.0 1.8e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 BolA-like protein COX15-CtaA PF02628.15 KLO07479.1 - 1.8e-103 346.0 7.9 2.2e-103 345.8 7.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein FAD_binding_4 PF01565.23 KLO07481.1 - 8.1e-29 100.1 4.2 8.1e-29 100.1 4.2 1.5 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KLO07481.1 - 1.5e-08 34.6 0.2 3e-08 33.6 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like MS_channel PF00924.18 KLO07482.1 - 4.2e-18 65.7 0.1 7.6e-18 64.8 0.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KLO07482.1 - 8.1e-06 25.0 0.1 2.2e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KLO07482.1 - 0.00016 21.3 1.3 0.00024 20.8 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KLO07482.1 - 0.00022 20.6 0.1 0.00047 19.5 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KLO07482.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair PBP1_TM PF14812.6 KLO07482.1 - 0.013 15.8 0.7 1.3 9.4 0.0 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-hand_7 PF13499.6 KLO07482.1 - 0.026 15.0 0.2 0.092 13.2 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair FAD_binding_4 PF01565.23 KLO07485.1 - 1e-31 109.5 2.5 2.2e-30 105.2 4.1 2.3 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 KLO07485.1 - 2e-08 34.2 0.1 4.3e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like TrbC_Ftype PF09673.10 KLO07485.1 - 0.14 12.2 0.0 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein FAD_binding_4 PF01565.23 KLO07486.1 - 1.3e-22 80.0 1.8 2.4e-22 79.1 1.1 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KLO07486.1 - 1.5e-09 37.8 0.1 3.4e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KLO07487.1 - 2.5e-24 85.6 1.6 5.3e-24 84.5 1.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KLO07487.1 - 1.6e-07 31.3 0.2 2.8e-07 30.5 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KLO07487.1 - 0.041 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding AMPK1_CBM PF16561.5 KLO07489.1 - 1.7e-15 57.0 0.1 2.7e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase GTP_EFTU PF00009.27 KLO07490.1 - 7.1e-32 110.5 0.0 9e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KLO07490.1 - 1e-11 45.1 0.1 6.1e-11 42.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KLO07490.1 - 0.00026 21.3 0.1 0.00047 20.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KLO07490.1 - 0.03 14.4 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase HBS1_N PF08938.10 KLO07492.1 - 5.3e-11 42.7 1.7 1.1e-10 41.6 1.7 1.5 1 0 0 1 1 1 1 HBS1 N-terminus SSB PF00436.25 KLO07493.1 - 1.2e-14 54.2 0.0 1.6e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family UL42 PF17638.2 KLO07493.1 - 0.085 12.8 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 HCMV UL42 Haem_degrading PF03928.14 KLO07494.1 - 5.7e-07 29.6 0.0 1.8e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Haem-degrading Pex2_Pex12 PF04757.14 KLO07495.1 - 7.2e-47 159.9 6.1 8.5e-47 159.6 6.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KLO07495.1 - 8.1e-07 28.8 0.7 1.2e-06 28.2 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO07495.1 - 7e-05 22.6 1.5 0.00011 21.9 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO07495.1 - 0.0004 20.6 1.2 0.00072 19.8 1.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KLO07495.1 - 0.0036 17.1 1.7 0.0058 16.5 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KLO07495.1 - 0.0082 16.3 3.2 0.013 15.6 3.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KLO07495.1 - 0.076 13.1 3.6 0.14 12.2 3.6 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KLO07495.1 - 0.46 10.4 2.7 4.2 7.3 0.1 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KLO07495.1 - 0.67 9.8 7.1 3.5 7.5 0.6 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain SPX PF03105.19 KLO07496.1 - 7.1e-28 98.6 9.6 1.7e-09 38.1 0.1 3.0 1 1 2 3 3 3 3 SPX domain PNMA PF14893.6 KLO07496.1 - 0.016 14.7 0.2 0.023 14.1 0.2 1.3 1 1 0 1 1 1 0 PNMA Peripla_BP_2 PF01497.18 KLO07496.1 - 0.061 12.9 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Pectinesterase PF01095.19 KLO07497.1 - 5.6e-36 123.8 1.3 1.2e-31 109.6 0.9 2.1 2 0 0 2 2 2 2 Pectinesterase Peptidase_S8 PF00082.22 KLO07498.1 - 9.7e-31 107.1 1.7 1.7e-30 106.3 1.7 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KLO07498.1 - 4.3e-28 97.2 0.3 8.8e-28 96.2 0.3 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KLO07498.1 - 0.099 13.4 0.2 0.78 10.5 0.3 2.5 2 1 0 2 2 2 0 Peptidase S8 pro-domain Podoplanin PF05808.11 KLO07498.1 - 0.12 12.5 1.6 0.14 12.2 0.2 1.8 2 0 0 2 2 2 0 Podoplanin DUF2914 PF11141.8 KLO07498.1 - 0.12 12.2 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) PRKCSH-like PF12999.7 KLO07499.1 - 2.3e-49 167.5 1.1 6.9e-49 166.0 1.1 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KLO07499.1 - 1.1e-25 90.1 0.0 2.6e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KLO07499.1 - 3.3e-09 37.6 1.3 1e-08 36.0 1.3 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Con-6 PF10346.9 KLO07499.1 - 0.048 13.7 0.1 0.18 11.9 0.1 2.1 1 0 0 1 1 1 0 Conidiation protein 6 PP_kinase PF02503.17 KLO07499.1 - 0.071 12.7 0.3 0.15 11.6 0.3 1.4 1 0 0 1 1 1 0 Polyphosphate kinase middle domain Ribosomal_S25 PF03297.15 KLO07500.1 - 2.5e-36 123.9 4.8 3.4e-36 123.5 4.8 1.2 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 KLO07500.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 KLO07500.1 - 0.038 14.3 0.1 0.06 13.7 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator FtsK_gamma PF09397.10 KLO07500.1 - 0.039 13.8 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Ftsk gamma domain MarR PF01047.22 KLO07500.1 - 0.077 12.9 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.19 KLO07500.1 - 0.11 12.7 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Apq12 PF12716.7 KLO07501.1 - 0.71 9.9 3.2 0.99 9.4 3.2 1.2 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis HIG_1_N PF04588.13 KLO07502.1 - 3.4e-07 30.4 0.7 8e-07 29.2 0.7 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region HIG_1_N PF04588.13 KLO07503.1 - 6.6e-05 23.0 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PMT PF02366.18 KLO07503.1 - 0.025 14.1 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase FlgN PF05130.12 KLO07504.1 - 0.00043 20.8 7.8 0.0048 17.4 0.1 2.3 2 0 0 2 2 2 1 FlgN protein Filament PF00038.21 KLO07504.1 - 0.002 17.8 6.4 0.03 13.9 1.4 2.3 2 0 0 2 2 2 1 Intermediate filament protein Shugoshin_N PF07558.11 KLO07504.1 - 0.0051 16.6 1.4 1.6 8.7 0.0 3.2 3 0 0 3 3 3 1 Shugoshin N-terminal coiled-coil region HIP1_clath_bdg PF16515.5 KLO07504.1 - 0.028 15.0 1.9 0.028 15.0 1.9 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 KLO07504.1 - 0.032 14.4 12.4 1 9.5 0.5 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) KxDL PF10241.9 KLO07504.1 - 0.034 14.4 3.8 1.4 9.3 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein KASH_CCD PF14662.6 KLO07504.1 - 0.039 13.8 10.6 0.56 10.0 1.3 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KLO07504.1 - 0.07 13.2 11.6 0.36 11.0 1.3 3.5 3 1 0 3 3 2 0 bZIP transcription factor Rab5-bind PF09311.11 KLO07504.1 - 0.077 12.4 7.0 0.065 12.6 0.8 2.2 2 0 0 2 2 2 0 Rabaptin-like protein LMBR1 PF04791.16 KLO07504.1 - 0.12 11.3 1.5 0.14 11.0 1.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 KLO07504.1 - 0.13 11.6 5.8 0.67 9.2 2.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) KfrA_N PF11740.8 KLO07504.1 - 0.16 12.7 13.4 0.34 11.6 0.6 2.5 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term HAUS-augmin3 PF14932.6 KLO07504.1 - 0.17 11.4 11.4 0.48 10.0 2.8 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 CK2S PF15011.6 KLO07504.1 - 0.18 11.7 3.7 0.35 10.7 0.5 2.2 2 0 0 2 2 2 0 Casein Kinase 2 substrate DUF4140 PF13600.6 KLO07504.1 - 0.21 12.1 9.5 1.7 9.2 2.2 2.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Cep57_CLD_2 PF14197.6 KLO07504.1 - 0.5 10.5 10.8 1.2 9.3 2.3 2.7 2 1 0 3 3 3 0 Centrosome localisation domain of PPC89 JIP_LZII PF16471.5 KLO07504.1 - 0.58 10.4 8.3 13 6.0 0.7 3.2 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Tmemb_cc2 PF10267.9 KLO07504.1 - 0.66 9.1 6.9 2.2 7.3 0.8 2.0 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Prefoldin PF02996.17 KLO07504.1 - 0.71 9.8 7.1 0.16 11.8 1.7 2.3 2 0 0 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.8 KLO07504.1 - 0.74 10.1 9.4 2.6 8.3 0.6 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-H PF05837.12 KLO07504.1 - 0.82 10.1 12.1 2.5 8.5 3.2 2.6 2 1 1 3 3 3 0 Centromere protein H (CENP-H) YabA PF06156.13 KLO07504.1 - 0.99 10.1 6.7 4.9 7.9 0.2 2.7 2 1 0 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 KLO07504.1 - 1.1 9.0 6.8 6.5 6.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) GrpE PF01025.19 KLO07504.1 - 1.1 8.8 5.8 11 5.6 0.2 2.4 2 0 0 2 2 2 0 GrpE LPP PF04728.13 KLO07504.1 - 1.2 9.5 9.7 9.8 6.7 1.9 3.3 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Cep57_MT_bd PF06657.13 KLO07504.1 - 2.2 8.8 8.6 2.4 8.7 0.4 2.9 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF4200 PF13863.6 KLO07504.1 - 2.7 8.4 11.8 3.4 8.1 3.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 KLO07504.1 - 2.8 6.7 12.3 0.34 9.8 3.9 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Cnn_1N PF07989.11 KLO07504.1 - 3.8 7.7 10.4 12 6.1 0.9 3.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 KLO07504.1 - 4.6 7.3 8.5 41 4.2 0.1 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus M PF02370.16 KLO07504.1 - 5 8.0 10.9 49 5.0 0.1 4.1 3 2 1 4 4 4 0 M protein repeat Rx_N PF18052.1 KLO07504.1 - 6.5 7.1 7.4 0.97 9.8 0.8 2.8 3 2 0 3 3 2 0 Rx N-terminal domain CLZ PF16526.5 KLO07504.1 - 7 7.1 12.2 6.1 7.3 4.4 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 KLO07504.1 - 7.6 6.4 14.1 14 5.6 0.4 3.2 2 1 1 3 3 3 0 Septum formation initiator TPR_MLP1_2 PF07926.12 KLO07504.1 - 8.1 6.5 16.3 15 5.7 6.5 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Swi5 PF07061.11 KLO07504.1 - 8.5 6.6 10.0 14 5.9 0.7 3.1 2 1 1 3 3 3 0 Swi5 Exonuc_VII_L PF02601.15 KLO07504.1 - 8.7 5.8 9.6 20 4.6 9.6 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4226 PF10774.9 KLO07504.1 - 9.3 6.6 11.4 1.6 9.1 2.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4226) Cyt-b5 PF00173.28 KLO07506.1 - 2.5e-21 75.6 0.0 3.3e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CDC14 PF08045.11 KLO07507.1 - 2.1e-35 122.2 8.0 1.9e-19 69.9 0.0 4.0 3 1 1 4 4 4 4 Cell division control protein 14, SIN component RYDR_ITPR PF01365.21 KLO07507.1 - 0.062 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 RIH domain FAA_hydrolase PF01557.18 KLO07508.1 - 2.2e-62 210.6 0.0 3.2e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase PF01557.18 KLO07509.1 - 1.9e-61 207.5 0.0 2.9e-61 206.9 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Aldedh PF00171.22 KLO07510.1 - 3.6e-164 546.7 0.5 4.1e-164 546.5 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ldh_2 PF02615.14 KLO07510.1 - 0.039 13.1 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase DUF2878 PF11086.8 KLO07511.1 - 0.015 15.5 2.2 0.018 15.2 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2878) DUF969 PF06149.12 KLO07512.1 - 0.34 10.3 5.7 0.058 12.8 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF969) TctB PF07331.11 KLO07513.1 - 9.6 6.5 7.8 0.8 10.0 1.3 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Ytp1 PF10355.9 KLO07515.1 - 3.1e-105 351.4 9.0 5.1e-105 350.7 9.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KLO07515.1 - 7.4e-16 57.8 2.0 7.4e-16 57.8 2.0 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) UbiA PF01040.18 KLO07516.1 - 7.7e-54 182.6 19.7 1e-53 182.2 19.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Rho_GDI PF02115.17 KLO07517.1 - 3.6e-53 180.2 0.1 4.2e-53 180.0 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP_dimer PF03717.15 KLO07517.1 - 0.098 13.0 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain zf-CCCH PF00642.24 KLO07518.1 - 0.044 13.7 19.6 0.15 12.1 1.2 3.6 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KLO07518.1 - 0.35 11.0 16.9 4 7.6 0.4 3.8 4 0 0 4 4 4 0 Zinc finger domain DUF4482 PF14818.6 KLO07518.1 - 0.46 11.4 4.7 1.1 10.1 4.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Tropomyosin_1 PF12718.7 KLO07518.1 - 0.5 10.5 6.9 1.3 9.2 6.9 1.6 1 1 0 1 1 1 0 Tropomyosin like zf_CCCH_4 PF18345.1 KLO07519.1 - 0.023 14.8 1.9 0.023 14.8 1.9 4.2 3 1 2 5 5 5 0 Zinc finger domain Pkinase PF00069.25 KLO07521.1 - 1.4e-38 132.8 0.0 1.8e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO07521.1 - 2.3e-36 125.4 0.0 2.8e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO07521.1 - 6.2e-06 25.7 0.1 1.4e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO07521.1 - 0.0032 16.3 0.1 0.0042 15.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KLO07521.1 - 0.0035 17.0 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KLO07521.1 - 0.0095 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KLO07521.1 - 0.066 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KLO07521.1 - 0.089 12.7 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family G-alpha PF00503.20 KLO07523.1 - 5e-113 377.9 0.0 8.9e-113 377.0 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO07523.1 - 2.4e-11 43.4 0.3 3.9e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KLO07523.1 - 0.0019 18.4 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KLO07523.1 - 0.0077 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein DUF815 PF05673.13 KLO07523.1 - 0.011 14.9 0.1 0.019 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 KLO07523.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 KLO07523.1 - 0.093 11.9 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 KLO07523.1 - 0.17 11.6 0.1 0.37 10.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF3959 PF13105.6 KLO07524.1 - 3.1 7.2 6.5 15 5.0 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Zn_clus PF00172.18 KLO07526.1 - 2.6e-07 30.7 5.0 5.8e-07 29.5 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spc29 PF17082.5 KLO07526.1 - 0.056 13.3 0.2 0.056 13.3 0.2 2.3 3 0 0 3 3 3 0 Spindle Pole Component 29 OPT PF03169.15 KLO07527.1 - 7.2e-182 606.3 64.5 8.2e-182 606.1 64.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_M17 PF00883.21 KLO07529.1 - 4.2e-118 394.2 0.0 5.4e-118 393.8 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain F-box-like PF12937.7 KLO07530.1 - 0.00029 20.6 0.4 0.00072 19.4 0.2 1.8 2 0 0 2 2 2 1 F-box-like Peptidase_C48 PF02902.19 KLO07532.1 - 2.1e-10 40.8 0.0 4.5e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain peroxidase PF00141.23 KLO07533.1 - 2.5e-24 86.2 0.0 3.6e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase RNR_inhib PF08591.10 KLO07534.1 - 3.4e-06 28.3 1.7 5.7e-05 24.4 1.7 2.5 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Ribosomal_L29 PF00831.23 KLO07536.1 - 1.8e-19 69.4 3.3 1.8e-19 69.4 3.3 2.3 2 1 0 2 2 2 1 Ribosomal L29 protein Phage_HK97_TLTM PF06120.11 KLO07536.1 - 0.0025 17.0 3.9 0.0028 16.9 3.9 1.0 1 0 0 1 1 1 1 Tail length tape measure protein zf-H2C2_2 PF13465.6 KLO07538.1 - 1.9e-08 34.3 10.5 3.2e-05 24.1 1.0 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KLO07538.1 - 4.2e-06 26.9 17.1 9.6e-05 22.6 0.9 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO07538.1 - 0.00044 20.9 15.0 0.011 16.5 0.9 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KLO07538.1 - 0.21 11.7 0.2 0.21 11.7 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CHCC PF10276.9 KLO07538.1 - 0.82 9.8 3.2 4.3 7.5 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger domain Cid2 PF09774.9 KLO07539.1 - 1.5e-28 100.2 7.0 8.9e-28 97.7 7.0 1.9 1 1 0 1 1 1 1 Caffeine-induced death protein 2 Cep57_MT_bd PF06657.13 KLO07539.1 - 0.013 16.0 0.9 0.94 10.0 0.2 2.8 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 AurF PF11583.8 KLO07539.1 - 0.026 13.8 0.5 0.053 12.8 0.2 1.6 1 1 1 2 2 2 0 P-aminobenzoate N-oxygenase AurF KicB PF03882.14 KLO07539.1 - 0.037 14.2 0.9 4.6 7.5 0.1 2.1 2 0 0 2 2 2 0 MukF winged-helix domain GILT PF03227.16 KLO07540.1 - 2e-16 60.2 0.1 3.7e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) RRN3 PF05327.11 KLO07541.1 - 3.3e-185 616.9 0.0 3.3e-185 616.9 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 GDPD PF03009.17 KLO07541.1 - 0.054 13.2 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family SMN PF06003.12 KLO07541.1 - 0.39 9.9 3.0 0.82 8.9 3.0 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Y_phosphatase3 PF13350.6 KLO07542.1 - 2.2e-58 198.0 0.0 2.5e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KLO07542.1 - 0.0015 18.3 0.3 0.012 15.4 0.3 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 KLO07542.1 - 0.0033 17.0 0.1 0.017 14.7 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family NPR1_interact PF15699.5 KLO07542.1 - 0.0055 17.3 0.1 0.01 16.5 0.1 1.4 1 0 0 1 1 1 1 NPR1 interacting Y_phosphatase PF00102.27 KLO07542.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Vac14_Fig4_bd PF11916.8 KLO07543.1 - 6.2e-74 247.5 10.2 1.2e-73 246.6 10.2 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KLO07543.1 - 2.7e-38 130.5 0.0 3e-37 127.1 0.0 2.7 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KLO07543.1 - 1.1e-05 25.2 0.2 0.0099 16.1 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KLO07543.1 - 0.00025 21.1 1.4 0.96 9.5 0.0 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KLO07543.1 - 0.0021 17.7 0.1 0.8 9.2 0.0 3.3 4 0 0 4 4 4 1 CLASP N terminal TAF6_C PF07571.13 KLO07543.1 - 0.018 15.4 0.0 0.52 10.7 0.0 3.0 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 KLO07543.1 - 0.068 13.7 0.5 14 6.3 0.0 4.7 4 1 1 5 5 5 0 HEAT-like repeat SLAIN PF15301.6 KLO07543.1 - 2.9 7.1 15.3 11 5.2 15.0 1.9 1 1 1 2 2 2 0 SLAIN motif-containing family GFO_IDH_MocA PF01408.22 KLO07546.1 - 1.6e-16 61.2 0.0 2.8e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold EBP PF05241.12 KLO07547.1 - 0.0049 16.4 3.9 0.0074 15.8 3.9 1.3 1 1 0 1 1 1 1 Emopamil binding protein TMC PF07810.13 KLO07547.1 - 0.03 14.9 1.5 0.076 13.6 0.0 2.0 1 1 1 2 2 2 0 TMC domain DUF2681 PF10883.8 KLO07549.1 - 0.039 14.3 0.0 0.058 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Syndecan PF01034.20 KLO07549.1 - 0.23 11.4 0.2 0.37 10.7 0.2 1.2 1 0 0 1 1 1 0 Syndecan domain Pilt PF15453.6 KLO07550.1 - 0.16 11.4 2.4 0.23 10.8 2.4 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Acetyltransf_1 PF00583.25 KLO07551.1 - 2.4e-14 53.6 0.0 3.1e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KLO07551.1 - 5.5e-11 42.5 0.0 7.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO07551.1 - 7.4e-11 42.3 0.0 1.1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO07551.1 - 0.06 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Mo25 PF08569.11 KLO07552.1 - 3.9e-133 443.9 5.7 4.4e-133 443.7 5.7 1.0 1 0 0 1 1 1 1 Mo25-like ATG27 PF09451.10 KLO07553.1 - 2e-20 73.7 0.0 5.7e-20 72.3 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 KLO07553.1 - 0.098 12.7 0.1 0.31 11.1 0.1 1.8 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat adh_short PF00106.25 KLO07554.1 - 4.5e-30 104.6 0.0 3.2e-27 95.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KLO07554.1 - 7.7e-18 64.9 0.0 5.7e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO07554.1 - 1.5e-11 44.5 0.1 2.3e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO07554.1 - 1.8e-05 24.3 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO07554.1 - 0.00094 18.7 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KLO07554.1 - 0.0057 16.9 0.0 0.014 15.6 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KLO07554.1 - 0.02 14.1 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HHH PF00633.23 KLO07554.1 - 0.032 14.1 0.5 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF1776 PF08643.10 KLO07554.1 - 0.097 12.0 0.0 0.64 9.3 0.0 2.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) zf-RING_UBOX PF13445.6 KLO07556.1 - 2.2e-08 34.0 2.6 2.2e-08 34.0 2.6 2.3 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KLO07556.1 - 2.4e-08 33.7 5.4 5.2e-08 32.6 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO07556.1 - 1.2e-07 31.6 8.1 2.3e-07 30.7 8.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KLO07556.1 - 1.6e-07 31.5 8.5 3.4e-07 30.5 8.5 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KLO07556.1 - 1.4e-05 24.9 9.4 4.6e-05 23.2 9.5 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KLO07556.1 - 2.6e-05 24.0 8.6 5.6e-05 22.9 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO07556.1 - 5e-05 23.1 9.6 0.0001 22.0 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KLO07556.1 - 6.8e-05 22.6 4.4 0.00014 21.6 4.4 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KLO07556.1 - 0.00066 19.8 7.2 0.0041 17.2 7.3 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 KLO07556.1 - 0.0031 16.9 0.2 0.0047 16.3 0.2 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger FYVE PF01363.21 KLO07556.1 - 0.0069 16.5 5.3 0.16 12.1 2.0 2.5 1 1 1 2 2 2 1 FYVE zinc finger Baculo_IE-1 PF05290.11 KLO07556.1 - 0.052 13.5 1.2 0.11 12.4 1.2 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Zf_RING PF16744.5 KLO07556.1 - 0.058 13.5 6.5 0.076 13.1 3.9 2.3 2 1 1 3 3 3 0 KIAA1045 RING finger Rad50_zn_hook PF04423.14 KLO07556.1 - 0.083 12.7 0.9 0.17 11.8 0.9 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-rbx1 PF12678.7 KLO07556.1 - 0.093 13.0 8.1 0.26 11.6 8.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KLO07556.1 - 0.2 11.4 5.0 0.13 12.0 2.5 2.0 2 0 0 2 2 2 0 RING-like zinc finger Laminin_EGF PF00053.24 KLO07556.1 - 0.32 11.1 4.1 5.6 7.2 0.2 2.5 1 1 1 2 2 2 0 Laminin EGF domain zf-RING_6 PF14835.6 KLO07556.1 - 0.47 10.4 4.2 0.11 12.4 0.8 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Acyltransferase PF01553.21 KLO07559.1 - 1.9e-16 59.9 0.0 3.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Ribosomal_S11 PF00411.19 KLO07561.1 - 2.7e-47 159.7 1.7 3.4e-47 159.4 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KLO07561.1 - 0.099 12.9 0.1 0.21 11.8 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) HTH_3 PF01381.22 KLO07562.1 - 6.7e-09 35.7 0.0 8.2e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KLO07562.1 - 4.9e-06 26.8 0.0 6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KLO07562.1 - 2.4e-05 24.3 0.0 2.7e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KLO07562.1 - 7.8e-05 23.0 0.0 9.5e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain YdaS_antitoxin PF15943.5 KLO07562.1 - 0.0091 15.8 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_24 PF13412.6 KLO07562.1 - 0.028 14.0 0.0 0.25 11.0 0.0 2.2 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KLO07562.1 - 0.13 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KLO07562.1 - 0.22 11.4 0.0 0.38 10.6 0.0 1.4 2 0 0 2 2 2 0 Homeodomain-like domain ABC1 PF03109.16 KLO07564.1 - 3.1e-26 91.9 0.5 7.7e-26 90.6 0.1 1.8 2 0 0 2 2 2 1 ABC1 family DUF2786 PF10979.8 KLO07564.1 - 0.18 11.7 0.3 0.37 10.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) zf-C3HC4_3 PF13920.6 KLO07565.1 - 4.4e-07 29.6 8.8 8.5e-07 28.7 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO07565.1 - 3.7e-05 24.0 11.0 6.4e-05 23.2 11.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KLO07565.1 - 0.00015 21.5 10.9 0.00026 20.8 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO07565.1 - 0.00078 19.4 9.6 0.0013 18.7 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain FYVE PF01363.21 KLO07565.1 - 0.002 18.3 5.5 0.01 16.0 5.8 1.9 1 1 1 2 2 2 1 FYVE zinc finger zf-RING_UBOX PF13445.6 KLO07565.1 - 0.0039 17.2 7.0 0.0039 17.2 7.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 KLO07565.1 - 0.0072 16.1 8.6 0.014 15.2 8.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KLO07565.1 - 0.012 15.4 9.8 0.024 14.5 9.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KLO07565.1 - 0.039 13.8 10.7 0.077 12.9 10.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_2 PF14445.6 KLO07565.1 - 0.12 12.5 1.8 0.34 11.1 1.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Rtf2 PF04641.12 KLO07565.1 - 0.16 11.3 1.2 0.43 9.9 1.2 1.7 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C2HC5 PF06221.13 KLO07565.1 - 1.1 9.3 5.7 2.9 8.0 5.7 1.7 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-ACC PF17848.1 KLO07565.1 - 1.4 9.0 8.1 3.5 7.8 8.1 1.7 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain Baculo_IE-1 PF05290.11 KLO07565.1 - 2.2 8.2 3.6 4.2 7.3 3.6 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) C1_2 PF03107.16 KLO07565.1 - 3.4 8.0 6.3 0.66 10.3 2.5 1.8 2 0 0 2 2 1 0 C1 domain zf-C3HC4_4 PF15227.6 KLO07565.1 - 5.2 7.3 12.4 9.5 6.5 12.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Peptidase_C48 PF02902.19 KLO07566.1 - 4.3e-05 23.5 1.4 7.4e-05 22.7 1.4 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain KDZ PF18758.1 KLO07567.1 - 7.1e-74 248.2 0.1 1.1e-73 247.6 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KLO07567.1 - 0.0019 18.3 0.0 0.0053 16.9 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases DUF4829 PF16111.5 KLO07567.1 - 0.54 11.1 2.0 1 10.1 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4829) GCIP PF13324.6 KLO07569.1 - 0.55 9.8 4.1 0.43 10.1 2.2 1.8 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting ubiquitin PF00240.23 KLO07570.1 - 8.8e-261 842.4 49.5 2.5e-32 110.5 1.2 8.0 8 0 0 8 8 8 8 Ubiquitin family Rad60-SLD PF11976.8 KLO07570.1 - 1.1e-117 384.0 51.3 1.4e-14 53.6 1.0 8.0 8 0 0 8 8 8 8 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KLO07570.1 - 4e-41 139.4 28.7 0.00036 20.9 0.2 10.2 8 8 0 8 8 8 8 Ubiquitin-like domain TBK1_ULD PF18396.1 KLO07570.1 - 7.5e-32 109.1 12.7 0.0061 16.5 0.1 8.3 8 0 0 8 8 8 8 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KLO07570.1 - 5.9e-25 87.5 23.8 0.09 13.1 0.1 8.1 7 1 1 8 8 8 8 Ubiquitin-like domain DUF2407 PF10302.9 KLO07570.1 - 1.3e-24 86.7 8.7 0.26 11.9 0.0 8.2 1 1 1 8 8 8 8 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KLO07570.1 - 1.2e-19 70.4 14.1 0.58 10.3 0.1 9.1 8 0 0 8 8 8 8 Ubiquitin-2 like Rad60 SUMO-like UDP-g_GGTase PF06427.11 KLO07570.1 - 2.7e-11 43.5 20.8 3.5 7.8 0.1 8.4 9 0 0 9 9 9 5 UDP-glucose:Glycoprotein Glucosyltransferase DUF2870 PF11069.8 KLO07570.1 - 9.5e-10 38.7 0.0 79 3.7 0.0 8.5 8 1 0 8 8 8 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 KLO07570.1 - 1.6e-09 37.8 16.3 2.7 8.2 0.0 8.2 8 0 0 8 8 8 1 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 KLO07570.1 - 1.5e-07 31.1 16.8 25 4.8 0.0 8.3 8 0 0 8 8 8 0 ACT domain Ubiquitin_4 PF18036.1 KLO07570.1 - 1.3e-06 28.4 58.5 24 5.1 0.2 15.6 16 0 0 16 16 16 0 Ubiquitin-like domain Big_7 PF17957.1 KLO07570.1 - 1.6e-06 28.8 9.6 79 4.1 0.0 8.2 8 1 1 9 9 9 0 Bacterial Ig domain DUF493 PF04359.14 KLO07570.1 - 1.2e-05 25.8 5.2 1.7e+02 2.8 0.0 8.3 9 0 0 9 9 9 0 Protein of unknown function (DUF493) ACT_4 PF13291.6 KLO07570.1 - 0.00025 21.6 10.0 56 4.4 0.0 7.8 8 0 0 8 8 8 0 ACT domain ORF11CD3 PF10549.9 KLO07570.1 - 0.00098 19.2 0.0 4.5e+02 1.1 0.0 7.1 8 0 0 8 8 7 0 ORF11CD3 domain Baculo_p48 PF04878.13 KLO07570.1 - 0.0016 17.4 0.0 64 2.3 0.0 5.8 7 0 0 7 7 7 0 Baculovirus P48 protein TmoB PF06234.12 KLO07570.1 - 0.0038 17.3 15.1 60 3.8 0.0 7.9 8 0 0 8 8 8 0 Toluene-4-monooxygenase system protein B (TmoB) DUF1940 PF09155.10 KLO07570.1 - 0.18 11.9 15.0 29 4.8 0.1 7.3 8 0 0 8 8 8 0 Domain of unknown function (DUF1940) COX7a PF02238.15 KLO07570.1 - 0.22 11.9 0.6 0.59 10.6 0.6 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII ProRS-C_2 PF09181.10 KLO07570.1 - 0.47 10.6 21.6 86 3.4 0.1 7.8 8 0 0 8 8 8 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 KLO07570.1 - 1 9.6 61.4 1.4 9.1 1.6 8.3 8 0 0 8 8 8 0 Tash protein PEST motif CAP PF00188.26 KLO07573.1 - 4.6e-25 88.9 1.4 5.7e-25 88.6 1.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF5127 PF17168.4 KLO07574.1 - 3.3e-80 269.1 6.5 5.5e-80 268.4 6.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO07574.1 - 3.8e-76 254.6 0.1 6.7e-76 253.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO07574.1 - 6.7e-63 212.1 2.1 7e-63 212.0 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO07574.1 - 1.8e-09 37.0 0.3 6.4e-09 35.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KLO07574.1 - 0.027 13.9 0.2 0.054 13.0 0.2 1.5 1 1 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF2012 PF09430.10 KLO07575.1 - 2.8e-24 85.6 0.0 3.9e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) fn3_3 PF14686.6 KLO07575.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II SOP4 PF17081.5 KLO07575.1 - 0.18 11.3 0.1 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein zf-H2C2_2 PF13465.6 KLO07576.1 - 1.7e-07 31.3 1.9 8.9e-07 29.1 0.4 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KLO07576.1 - 3.6e-07 30.3 7.6 0.00078 19.8 2.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO07576.1 - 0.0004 21.0 6.2 0.072 14.0 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Ogr_Delta PF04606.12 KLO07576.1 - 0.049 13.6 0.4 9.8 6.3 0.1 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.6 KLO07576.1 - 0.055 13.5 2.0 0.15 12.1 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger S1FA PF04689.13 KLO07576.1 - 0.89 9.7 2.1 1.5 9.0 2.1 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA ELP6 PF09807.9 KLO07577.1 - 1.3e-14 54.3 0.0 1.6e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Elongation complex protein 6 AAA PF00004.29 KLO07577.1 - 0.0028 18.1 0.0 0.0068 16.8 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 KLO07577.1 - 0.018 14.5 0.0 0.049 13.1 0.0 1.7 1 1 0 1 1 1 0 Elongator subunit Iki1 Myb_Cef PF11831.8 KLO07578.1 - 1.9e-63 214.2 7.1 1.9e-63 214.2 7.1 4.8 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KLO07578.1 - 4.4e-21 74.8 6.6 9.4e-11 41.7 1.3 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KLO07578.1 - 2.7e-18 66.0 5.2 3.2e-12 46.5 2.8 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain GCH_III PF05165.12 KLO07578.1 - 0.066 12.5 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 GTP cyclohydrolase III Abhydrolase_6 PF12697.7 KLO07579.1 - 1e-15 59.0 0.0 1.4e-15 58.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO07579.1 - 2.5e-15 56.9 0.1 2.6e-14 53.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO07579.1 - 3.7e-08 32.9 0.0 3.5e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 KLO07579.1 - 0.0017 17.1 0.1 0.34 9.5 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 KLO07579.1 - 0.01 14.8 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KLO07579.1 - 0.011 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase FSH1 PF03959.13 KLO07579.1 - 0.1 12.2 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DLH PF01738.18 KLO07579.1 - 0.15 11.6 0.0 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KLO07580.1 - 3.9e-14 53.8 0.1 5.1e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO07580.1 - 6.4e-14 52.2 0.2 2.5e-13 50.3 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO07580.1 - 1.3e-05 24.6 0.0 3.1e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 KLO07580.1 - 0.018 13.7 0.1 3.7 6.1 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) FAD_binding_6 PF00970.24 KLO07581.1 - 1.8e-34 118.0 0.0 3.8e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KLO07581.1 - 6.1e-32 110.5 0.0 9.7e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KLO07581.1 - 8.7e-06 25.9 0.0 0.00021 21.4 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KLO07581.1 - 0.016 15.4 0.0 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain GST_N_3 PF13417.6 KLO07582.1 - 7.7e-07 29.4 0.0 3.8e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO07582.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KLO07582.1 - 0.084 13.2 0.0 0.36 11.2 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Fcf1 PF04900.12 KLO07582.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Fcf1 GluRS_N PF18466.1 KLO07582.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain Trs65 PF12735.7 KLO07583.1 - 2.3e-21 76.6 0.1 4.7e-13 49.2 0.1 3.2 2 1 0 2 2 2 2 TRAPP trafficking subunit Trs65 ANAPC4_WD40 PF12894.7 KLO07585.1 - 4e-11 43.1 0.0 0.0011 19.2 0.0 5.2 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO07585.1 - 2.9e-05 24.0 0.0 1.6 8.6 0.0 4.3 3 2 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KLO07585.1 - 3e-05 24.7 9.2 0.0012 19.6 0.2 5.4 7 0 0 7 7 7 1 WD domain, G-beta repeat PD40 PF07676.12 KLO07585.1 - 2.6 8.1 7.9 10 6.2 0.0 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.16 KLO07586.1 - 2.9e-41 141.6 38.5 1.5e-40 139.2 34.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KLO07586.1 - 1.2e-12 47.0 1.4 2.2e-12 46.2 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KLO07586.1 - 1.9e-11 43.5 20.1 6.4e-11 41.8 20.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KLO07586.1 - 8.3e-06 25.3 2.8 8.3e-06 25.3 2.8 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3481 PF11980.8 KLO07586.1 - 0.11 12.2 0.3 0.27 10.9 0.3 1.5 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein Pyr_redox_2 PF07992.14 KLO07587.1 - 9.9e-14 51.3 0.1 2.3e-10 40.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KLO07587.1 - 1.3e-13 50.3 0.4 1.1e-05 24.1 0.0 3.0 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KLO07587.1 - 8.6e-10 38.4 0.8 0.053 12.8 0.1 4.1 3 1 1 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO07587.1 - 2.8e-08 33.9 0.3 5.6e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KLO07587.1 - 8.4e-08 32.3 1.5 0.0083 16.1 0.1 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 KLO07587.1 - 1.3e-06 28.3 5.6 0.00013 21.7 0.5 3.8 3 1 0 4 4 4 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KLO07587.1 - 3.5e-06 26.6 0.9 0.0012 18.2 0.2 2.9 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 KLO07587.1 - 5.3e-06 25.8 2.5 0.052 12.7 0.5 3.3 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KLO07587.1 - 1.1e-05 24.7 1.5 0.064 12.3 0.2 3.1 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 KLO07587.1 - 0.00011 21.6 0.0 0.025 13.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KLO07587.1 - 0.0005 19.3 2.0 0.15 11.1 0.2 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 KLO07587.1 - 0.00056 18.7 3.4 0.12 11.0 0.2 2.8 3 0 0 3 3 3 2 HI0933-like protein Shikimate_DH PF01488.20 KLO07587.1 - 0.00056 20.0 0.0 0.12 12.4 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KLO07587.1 - 0.00058 19.2 0.5 0.16 11.2 0.1 2.5 3 0 0 3 3 3 2 Thi4 family Pyr_redox PF00070.27 KLO07587.1 - 0.00097 19.6 4.0 0.26 11.9 0.0 3.5 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KLO07587.1 - 0.0032 17.4 1.2 0.0097 15.8 0.2 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KLO07587.1 - 0.0065 15.8 0.6 2.8 7.2 0.1 2.6 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KLO07587.1 - 0.066 12.6 0.1 0.98 8.7 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PP2C PF00481.21 KLO07588.1 - 1.1e-35 123.6 0.0 2.4e-34 119.2 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KLO07588.1 - 0.035 14.0 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KLO07588.1 - 0.039 13.6 0.1 0.071 12.7 0.1 1.4 1 1 0 1 1 1 0 Protein phosphatase 2C 2-Hacid_dh_C PF02826.19 KLO07589.1 - 4.5e-54 182.5 0.0 9.3e-54 181.5 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KLO07589.1 - 2.9e-10 39.9 0.6 5.7e-10 39.0 0.1 1.6 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KLO07589.1 - 0.0021 18.3 0.0 0.052 13.7 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.26 KLO07589.1 - 0.027 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PaRep2a PF07903.11 KLO07589.1 - 0.2 11.5 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 PaRep2a protein His_Phos_2 PF00328.22 KLO07590.1 - 3.2e-47 161.7 0.0 4.2e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Git3 PF11710.8 KLO07591.1 - 0.001 18.9 11.4 0.001 18.9 11.4 2.2 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Luteo_Vpg PF01659.16 KLO07591.1 - 0.0058 16.9 0.2 0.012 15.9 0.2 1.5 1 0 0 1 1 1 1 Luteovirus putative VPg genome linked protein 7tm_1 PF00001.21 KLO07591.1 - 0.017 14.4 12.8 0.064 12.6 8.2 2.5 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) RPN2_C PF18004.1 KLO07592.1 - 2.6e-46 157.4 14.2 1.3e-42 145.4 13.3 3.1 2 1 0 2 2 2 2 26S proteasome regulatory subunit RPN2 C-terminal domain Dishevelled PF02377.15 KLO07592.1 - 0.0037 17.7 1.9 0.0059 17.1 1.9 1.2 1 0 0 1 1 1 1 Dishevelled specific domain Plavaka PF18759.1 KLO07593.1 - 4.8e-54 183.8 0.0 9.3e-43 146.7 0.1 2.2 1 1 1 2 2 2 2 Plavaka transposase NACHT PF05729.12 KLO07595.1 - 1.1e-11 44.9 0.1 3.1e-10 40.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KLO07595.1 - 3.4e-08 34.1 0.1 0.0039 17.6 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KLO07595.1 - 3.5e-07 30.6 0.1 9.5e-05 22.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain Parvo_NS1 PF01057.17 KLO07595.1 - 1.5e-05 24.2 1.0 0.042 12.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KLO07595.1 - 5.1e-05 22.6 0.0 0.00088 18.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 KLO07595.1 - 0.00082 19.3 0.6 0.29 11.0 0.1 2.3 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA PF00004.29 KLO07595.1 - 0.00099 19.5 0.0 0.043 14.2 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KLO07595.1 - 0.0021 18.4 0.2 0.59 10.6 0.1 2.7 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 KLO07595.1 - 0.0056 16.4 0.3 0.081 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KLO07595.1 - 0.027 14.6 1.0 0.26 11.4 0.0 2.9 3 1 0 3 3 2 0 AAA domain PIF1 PF05970.14 KLO07595.1 - 0.048 12.8 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase PhoH PF02562.16 KLO07595.1 - 0.067 12.6 0.1 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Torsin PF06309.11 KLO07595.1 - 0.078 13.1 0.0 6.7 6.8 0.0 2.8 3 0 0 3 3 3 0 Torsin ABC_tran PF00005.27 KLO07595.1 - 0.14 12.6 0.0 0.63 10.6 0.0 2.1 2 0 0 2 2 1 0 ABC transporter AAA_18 PF13238.6 KLO07595.1 - 0.15 12.6 0.3 1.3 9.5 0.2 2.7 1 1 0 1 1 1 0 AAA domain Sox17_18_mid PF12067.8 KLO07603.1 - 0.072 13.2 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Sox 17/18 central domain TFIIA PF03153.13 KLO07603.1 - 3.4 7.5 19.1 0.21 11.5 7.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit VPS53_C PF16854.5 KLO07605.1 - 0.054 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus NACHT PF05729.12 KLO07607.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NACHT PF05729.12 KLO07609.1 - 2.8e-12 46.9 0.0 6.2e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KLO07609.1 - 6.9e-07 29.6 0.0 2.5e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO07609.1 - 1.2e-05 25.7 0.0 4.9e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KLO07609.1 - 0.00075 19.9 0.0 0.0042 17.5 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KLO07609.1 - 0.0046 16.2 0.0 0.009 15.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Parvo_NS1 PF01057.17 KLO07609.1 - 0.0048 16.0 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 KLO07609.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KLO07609.1 - 0.029 14.8 0.3 0.15 12.4 0.0 2.4 3 0 0 3 3 2 0 RNA helicase ABC_tran PF00005.27 KLO07609.1 - 0.072 13.6 0.0 0.45 11.0 0.0 2.4 3 0 0 3 3 3 0 ABC transporter APS_kinase PF01583.20 KLO07609.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase PhoH PF02562.16 KLO07609.1 - 0.17 11.3 0.1 0.35 10.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Slx4 PF09494.10 KLO07610.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Slx4 endonuclease Parvo_NS1 PF01057.17 KLO07610.1 - 0.024 13.7 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_16 PF13191.6 KLO07610.1 - 0.081 13.3 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain 3Beta_HSD PF01073.19 KLO07614.1 - 7.2e-65 218.8 0.0 1.6e-58 198.0 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KLO07614.1 - 1.9e-31 109.4 0.0 2.7e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO07614.1 - 3.5e-14 52.9 0.0 2.4e-12 46.9 0.1 2.7 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KLO07614.1 - 2.7e-11 43.7 0.1 4e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KLO07614.1 - 9.6e-11 41.3 0.0 1.8e-06 27.3 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KLO07614.1 - 3e-10 39.7 0.0 5.2e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KLO07614.1 - 2.5e-05 23.5 0.4 0.00028 20.1 0.6 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KLO07614.1 - 0.0023 17.5 1.3 0.036 13.6 1.3 2.2 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 KLO07614.1 - 0.016 15.1 1.2 0.098 12.6 0.8 2.2 1 1 0 1 1 1 0 KR domain Nbl1_Borealin_N PF10444.9 KLO07615.1 - 5.4e-16 58.0 0.1 1.4e-15 56.6 0.1 1.8 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Borealin PF10512.9 KLO07615.1 - 6e-06 26.2 4.7 3e-05 24.0 0.9 3.1 3 0 0 3 3 3 1 Cell division cycle-associated protein 8 POP1 PF06978.11 KLO07616.1 - 8.3e-46 156.6 15.9 4.6e-24 85.5 4.9 2.3 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KLO07616.1 - 2.6e-32 111.0 0.5 2.6e-32 111.0 0.5 2.0 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 KLO07616.1 - 0.012 15.0 0.0 2.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KLO07616.1 - 0.029 14.3 0.0 0.084 12.8 0.0 1.8 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain DUF3421 PF11901.8 KLO07617.1 - 6.2e-29 100.3 0.8 1.9e-23 82.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) Spc7 PF08317.11 KLO07618.1 - 0.019 13.8 0.3 0.027 13.4 0.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RRF PF01765.19 KLO07618.1 - 0.068 13.1 0.4 0.11 12.4 0.4 1.3 1 0 0 1 1 1 0 Ribosome recycling factor CCDC-167 PF15188.6 KLO07618.1 - 0.071 13.5 1.1 0.12 12.7 1.1 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 SbcD_C PF12320.8 KLO07618.1 - 0.083 13.2 0.1 0.46 10.8 0.0 1.9 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Pkinase PF00069.25 KLO07619.1 - 5.1e-13 49.0 0.0 1.9e-12 47.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO07619.1 - 1.4e-05 24.6 0.0 7.3e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase YL1 PF05764.13 KLO07619.1 - 1.7e-05 25.0 2.6 2.4e-05 24.6 2.6 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 KLO07619.1 - 0.043 12.1 6.6 0.057 11.7 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 KLO07619.1 - 0.048 13.5 2.6 0.11 12.4 2.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Pkinase_fungal PF17667.1 KLO07619.1 - 0.051 12.4 1.0 0.059 12.1 0.1 1.5 2 0 0 2 2 2 0 Fungal protein kinase BUD22 PF09073.10 KLO07619.1 - 0.12 11.7 8.6 0.19 11.0 8.6 1.3 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 KLO07619.1 - 0.14 11.8 5.5 0.31 10.7 5.5 1.5 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 KLO07619.1 - 0.32 9.2 12.1 0.47 8.6 12.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4637 PF15470.6 KLO07619.1 - 1.5 8.5 7.0 3.5 7.3 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Astro_capsid_p PF12226.8 KLO07619.1 - 1.6 7.8 7.9 2.7 7.1 7.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein GCIP PF13324.6 KLO07619.1 - 6.3 6.3 6.5 12 5.5 6.5 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RRN3 PF05327.11 KLO07619.1 - 6.8 5.1 7.0 11 4.4 7.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pkinase PF00069.25 KLO07620.1 - 4.4e-44 150.8 0.0 6.4e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO07620.1 - 8.1e-23 81.0 0.0 3.6e-22 78.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO07620.1 - 1.9e-05 24.2 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO07620.1 - 5.1e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO07620.1 - 0.00064 18.6 0.0 0.0027 16.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KLO07620.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF4551 PF15087.6 KLO07621.1 - 1.1 8.1 2.9 1.1 8.0 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HhH-GPD PF00730.25 KLO07623.1 - 1.3e-08 35.2 0.0 2.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein AAA_5 PF07728.14 KLO07624.1 - 1.8e-114 377.9 0.0 3.7e-27 95.0 0.0 8.8 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KLO07624.1 - 1.6e-56 189.0 8.6 2.7e-24 85.4 0.0 4.9 5 0 0 5 5 3 3 Midasin AAA lid domain AAA_3 PF07726.11 KLO07624.1 - 8.2e-27 93.6 0.0 5.3e-08 32.8 0.0 6.3 7 0 0 7 7 5 4 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 KLO07624.1 - 1.2e-24 86.4 0.1 3.7e-24 84.8 0.1 1.9 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_16 PF13191.6 KLO07624.1 - 2.4e-22 80.1 7.6 0.0018 18.7 0.0 8.8 8 3 0 8 8 7 5 AAA ATPase domain AAA PF00004.29 KLO07624.1 - 2.8e-21 76.3 0.0 2.3e-05 24.8 0.0 6.6 6 0 0 6 6 5 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO07624.1 - 1.4e-17 64.2 1.0 0.0029 17.9 0.0 7.3 7 0 0 7 7 7 3 AAA domain AAA_18 PF13238.6 KLO07624.1 - 1e-16 61.7 0.0 0.19 12.3 0.0 7.1 6 0 0 6 6 6 4 AAA domain Dynein_heavy PF03028.15 KLO07624.1 - 1.4e-16 60.6 0.0 0.015 15.4 0.0 7.1 7 0 0 7 7 5 4 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 KLO07624.1 - 8.4e-16 58.0 0.2 0.0026 17.3 0.1 5.9 6 0 0 6 6 6 3 P-loop containing dynein motor region Sigma54_activat PF00158.26 KLO07624.1 - 6.9e-15 55.2 0.0 0.02 14.6 0.0 5.7 5 0 0 5 5 5 3 Sigma-54 interaction domain AAA_14 PF13173.6 KLO07624.1 - 2.6e-13 50.1 0.0 0.019 15.0 0.0 6.6 8 0 0 8 8 5 4 AAA domain AAA_30 PF13604.6 KLO07624.1 - 1.2e-12 48.0 0.0 0.073 12.8 0.0 6.9 7 1 0 7 7 7 2 AAA domain T2SSE PF00437.20 KLO07624.1 - 2.2e-12 46.6 0.1 0.093 11.8 0.1 6.0 6 0 0 6 6 6 3 Type II/IV secretion system protein AAA_6 PF12774.7 KLO07624.1 - 2.5e-12 46.4 0.0 0.21 10.5 0.0 6.7 6 0 0 6 6 6 3 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 KLO07624.1 - 2.8e-10 40.5 0.0 0.098 12.8 0.0 5.5 5 0 0 5 5 5 1 AAA domain TsaE PF02367.17 KLO07624.1 - 5.6e-10 39.3 0.8 1.1 9.2 0.0 6.4 6 0 0 6 6 6 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KLO07624.1 - 5.4e-09 35.7 1.0 0.22 11.3 0.0 5.7 6 0 0 6 6 5 2 P-loop containing region of AAA domain ABC_tran PF00005.27 KLO07624.1 - 1e-08 35.8 0.3 0.68 10.4 0.0 6.0 6 0 0 6 6 5 2 ABC transporter RNA_helicase PF00910.22 KLO07624.1 - 1.6e-08 34.9 0.0 7 7.1 0.0 6.2 5 0 0 5 5 5 0 RNA helicase NACHT PF05729.12 KLO07624.1 - 9.2e-08 32.2 0.3 0.55 10.1 0.0 5.1 4 0 0 4 4 4 1 NACHT domain Zeta_toxin PF06414.12 KLO07624.1 - 1e-07 31.4 0.0 1 8.6 0.0 5.5 5 0 0 5 5 5 1 Zeta toxin AAA_28 PF13521.6 KLO07624.1 - 1.3e-07 32.1 3.5 1.3 9.3 0.0 7.1 7 0 0 7 7 7 1 AAA domain IstB_IS21 PF01695.17 KLO07624.1 - 2.6e-06 27.3 0.0 0.91 9.2 0.0 4.8 5 0 0 5 5 4 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KLO07624.1 - 3.9e-06 26.4 4.8 9.5 5.5 0.0 7.0 6 2 1 7 7 6 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 KLO07624.1 - 4.4e-06 27.3 3.8 6.7 7.2 0.0 5.9 6 0 0 6 6 5 0 AAA domain AAA_19 PF13245.6 KLO07624.1 - 6.8e-06 26.5 3.2 4.5 7.6 0.0 6.2 6 0 0 6 6 5 0 AAA domain DUF815 PF05673.13 KLO07624.1 - 9.1e-06 25.0 0.3 1.5 7.9 0.0 4.4 4 0 0 4 4 4 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 KLO07624.1 - 9.3e-06 25.8 0.2 0.19 11.8 0.0 4.6 5 0 0 5 5 3 1 Sigma-54 interaction domain AAA_25 PF13481.6 KLO07624.1 - 1.9e-05 24.3 2.5 1.9 8.0 0.0 5.0 4 0 0 4 4 4 1 AAA domain NTPase_1 PF03266.15 KLO07624.1 - 3e-05 24.0 2.6 3.4 7.5 0.0 5.1 5 0 0 5 5 4 0 NTPase RuvB_N PF05496.12 KLO07624.1 - 0.0001 22.1 1.5 0.65 9.7 0.0 5.2 5 1 0 5 5 3 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KLO07624.1 - 0.00041 19.7 0.3 0.11 11.7 0.0 4.0 5 0 0 5 5 5 1 TIP49 P-loop domain DEAD PF00270.29 KLO07624.1 - 0.00051 19.9 0.3 10 5.9 0.0 4.3 4 0 0 4 4 4 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 KLO07624.1 - 0.0014 18.4 0.0 5.4 6.7 0.0 4.5 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KLO07624.1 - 0.0021 17.8 0.0 17 5.1 0.0 4.5 5 0 0 5 5 5 0 AAA domain Rad17 PF03215.15 KLO07624.1 - 0.0027 17.7 2.8 26 4.7 0.0 5.3 6 0 0 6 6 5 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 KLO07624.1 - 0.0028 17.5 0.4 11 5.8 0.0 3.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 KLO07624.1 - 0.003 17.2 0.8 5 6.7 0.0 3.7 5 0 0 5 5 3 0 SRP54-type protein, GTPase domain CbiA PF01656.23 KLO07624.1 - 0.0037 17.3 0.0 53 3.9 0.0 4.7 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_8 PF12780.7 KLO07624.1 - 0.0045 16.4 0.1 1.6 8.0 0.0 4.2 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 ATPase PF06745.13 KLO07624.1 - 0.0062 15.9 0.1 11 5.2 0.0 3.7 4 0 0 4 4 4 0 KaiC CPT PF07931.12 KLO07624.1 - 0.019 14.8 1.6 22 4.8 0.1 5.6 7 0 0 7 7 5 0 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 KLO07624.1 - 0.024 14.0 0.0 4.2 6.7 0.0 3.5 3 0 0 3 3 3 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 KLO07624.1 - 0.026 13.9 1.0 3.3 7.0 0.0 3.8 4 0 0 4 4 3 0 FtsK/SpoIIIE family MeaB PF03308.16 KLO07624.1 - 0.029 13.4 0.9 40 3.1 0.0 3.9 4 0 0 4 4 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 KLO07624.1 - 0.037 14.0 0.0 15 5.6 0.0 3.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit VWA PF00092.28 KLO07624.1 - 0.044 14.0 0.6 0.14 12.4 0.6 1.9 1 0 0 1 1 1 0 von Willebrand factor type A domain KTI12 PF08433.10 KLO07624.1 - 0.1 12.0 0.0 10 5.5 0.0 3.7 4 0 0 4 4 3 0 Chromatin associated protein KTI12 PduV-EutP PF10662.9 KLO07624.1 - 0.12 12.1 0.2 5.2 6.8 0.0 3.5 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 KLO07624.1 - 0.16 11.8 1.7 7.4 6.4 0.0 4.1 5 0 0 5 5 4 0 Deoxynucleoside kinase Roc PF08477.13 KLO07624.1 - 0.26 11.5 2.5 43 4.3 0.0 4.4 5 0 0 5 5 4 0 Ras of Complex, Roc, domain of DAPkinase APS_kinase PF01583.20 KLO07624.1 - 0.29 11.0 0.7 31 4.4 0.0 4.1 4 0 0 4 4 4 0 Adenylylsulphate kinase AAA_11 PF13086.6 KLO07624.1 - 0.3 10.8 8.2 4.7 6.9 0.0 5.4 6 0 0 6 6 5 0 AAA domain F-box-like PF12937.7 KLO07625.1 - 2.8e-05 23.9 0.1 0.00011 22.0 0.1 2.1 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KLO07625.1 - 0.13 12.3 0.1 0.86 9.6 0.1 2.2 2 0 0 2 2 2 0 F-box-like domain HET PF06985.11 KLO07626.1 - 1.1e-06 29.0 0.1 0.0002 21.8 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) CTP_transf_like PF01467.26 KLO07627.1 - 0.0056 16.9 0.0 0.022 14.9 0.0 2.1 2 1 0 2 2 2 1 Cytidylyltransferase-like DUF1729 PF08354.10 KLO07628.1 - 6.3e-150 499.0 0.0 1.1e-149 498.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_I_H PF18314.1 KLO07628.1 - 1.1e-75 253.7 0.0 2.7e-75 252.5 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KLO07628.1 - 2.7e-73 245.6 0.0 1.1e-71 240.4 0.0 2.5 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain Acyl_transf_1 PF00698.21 KLO07628.1 - 2.3e-71 240.9 0.0 6.7e-69 232.8 0.0 3.6 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KLO07628.1 - 2.3e-45 154.0 0.0 5.3e-45 152.8 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KLO07628.1 - 7.5e-33 114.2 0.0 6.3e-32 111.2 0.0 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KLO07628.1 - 1.8e-26 92.1 0.1 1.4e-25 89.2 0.0 2.6 2 0 0 2 2 2 1 MaoC like domain FAS_N PF17828.1 KLO07628.1 - 3.3e-23 82.1 0.1 6.4e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta ketoacyl-synt PF00109.26 KLO07628.1 - 3.6e-22 79.2 0.9 1.1e-21 77.6 0.5 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KLO07628.1 - 3.2e-15 56.3 0.0 8.2e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KLO07628.1 - 4.7e-13 49.2 0.1 4.7e-13 49.2 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain MaoC_dehydrat_N PF13452.6 KLO07628.1 - 9.6e-12 45.2 0.1 8.2e-11 42.2 0.1 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase adh_short PF00106.25 KLO07628.1 - 8.4e-05 22.1 0.0 0.00095 18.7 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KLO07628.1 - 0.091 12.7 0.9 0.16 11.8 0.0 1.9 2 0 0 2 2 1 0 KR domain Lebercilin PF15619.6 KLO07629.1 - 0.51 10.0 2.8 0.73 9.5 0.0 2.4 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease NPV_P10 PF05531.12 KLO07629.1 - 1.3 9.5 3.8 4.1 7.9 0.6 3.4 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DEAD PF00270.29 KLO07630.1 - 2.7e-35 121.7 0.3 4.5e-35 121.0 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO07630.1 - 2e-11 44.2 0.4 2.8e-07 30.9 0.1 2.9 1 1 1 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KLO07630.1 - 7.2e-05 23.1 0.2 0.01 16.1 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KLO07630.1 - 0.00099 18.9 0.1 0.011 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KLO07630.1 - 0.013 15.9 0.3 0.71 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF1269 PF06897.12 KLO07630.1 - 0.078 13.3 0.1 2.1 8.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) Mitofilin PF09731.9 KLO07632.1 - 3.1e-108 363.3 20.3 4.5e-108 362.8 20.3 1.2 1 1 0 1 1 1 1 Mitochondrial inner membrane protein DUF883 PF05957.13 KLO07632.1 - 0.011 16.4 2.1 0.011 16.4 2.1 4.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) V-ATPase_G_2 PF16999.5 KLO07632.1 - 0.39 11.1 23.3 0.11 13.0 1.5 4.0 3 1 1 4 4 4 0 Vacuolar (H+)-ATPase G subunit Cas_DxTHG PF09455.10 KLO07632.1 - 0.86 9.1 11.5 0.1 12.2 6.6 1.9 3 0 0 3 3 3 0 CRISPR-associated (Cas) DxTHG family FapA PF03961.13 KLO07632.1 - 3.1 6.3 12.8 0.9 8.1 0.7 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A ox_reductase_C PF08635.10 KLO07633.1 - 1.8e-72 241.6 0.0 3.2e-72 240.8 0.0 1.4 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 KLO07633.1 - 2.1e-20 73.7 0.0 3.3e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KLO07633.1 - 0.023 14.7 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain p450 PF00067.22 KLO07634.1 - 3e-72 243.9 0.0 4.6e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO07635.1 - 6.7e-70 236.1 0.0 8.7e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO07636.1 - 7.5e-63 212.9 0.0 1e-62 212.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO07637.1 - 4.2e-68 230.2 0.0 5.9e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NHase_alpha PF02979.16 KLO07638.1 - 0.15 11.4 0.2 5.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Nitrile hydratase, alpha chain ATP-synt_ab PF00006.25 KLO07639.1 - 9.1e-68 228.1 0.0 1.2e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KLO07639.1 - 6.1e-13 49.1 0.8 1.2e-12 48.2 0.8 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ctf8 PF09696.10 KLO07640.1 - 1.5e-17 64.2 1.3 1.1e-16 61.4 1.3 2.0 1 1 0 1 1 1 1 Ctf8 PH_10 PF15411.6 KLO07642.1 - 3.8e-22 78.8 0.0 7.7e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.6 KLO07642.1 - 2.6e-05 24.5 1.3 2.6e-05 24.5 1.3 1.8 2 0 0 2 2 2 1 Ring finger domain VWA_3 PF13768.6 KLO07642.1 - 7.9e-05 22.6 0.0 0.00036 20.5 0.0 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_UBOX PF13445.6 KLO07642.1 - 0.00012 22.0 3.5 0.00028 20.8 3.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger VWA PF00092.28 KLO07642.1 - 0.0002 21.7 0.0 0.00061 20.1 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.6 KLO07642.1 - 0.0052 16.7 1.1 0.022 14.7 1.4 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KLO07642.1 - 0.012 15.4 1.1 0.041 13.7 1.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO07642.1 - 0.027 14.3 0.7 0.054 13.4 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KLO07642.1 - 1.1 9.0 4.1 0.61 9.9 1.7 1.9 2 0 0 2 2 2 0 RING-like zinc finger Zds_C PF08632.10 KLO07643.1 - 1.9e-27 94.8 0.8 3.9e-27 93.8 0.8 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF4746 PF15928.5 KLO07643.1 - 0.82 9.0 12.2 0.027 13.9 5.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 KLO07643.1 - 3 6.0 6.1 6.2 5.0 6.1 1.5 1 0 0 1 1 1 0 CDC45-like protein IBR PF01485.21 KLO07646.1 - 1e-13 51.3 22.1 4.7e-08 33.1 4.6 3.3 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KLO07646.1 - 0.0014 18.9 0.5 0.0014 18.9 0.5 4.8 2 2 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KLO07646.1 - 0.017 15.0 0.4 0.017 15.0 0.4 4.0 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KLO07646.1 - 0.033 13.9 1.1 0.033 13.9 1.1 3.9 5 0 0 5 5 5 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KLO07646.1 - 0.09 12.6 0.3 0.09 12.6 0.3 4.4 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 KLO07646.1 - 2.7 8.2 16.6 2.2 8.4 9.0 3.0 2 1 0 2 2 2 0 Zinc-binding RING-finger MTHFR PF02219.17 KLO07647.1 - 6.3e-104 347.3 0.0 8.5e-104 346.9 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PH_12 PF16457.5 KLO07648.1 - 7.7e-32 110.6 0.0 1.3e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 KLO07648.1 - 1.9e-29 103.1 0.0 3.1e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 KLO07648.1 - 6.5e-26 91.1 0.0 3.9e-25 88.6 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3361) E1-E2_ATPase PF00122.20 KLO07649.1 - 8e-48 162.3 2.1 8e-48 162.3 2.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KLO07649.1 - 8.8e-32 111.1 0.9 2.9e-31 109.4 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KLO07649.1 - 3.2e-27 94.7 0.0 2.2e-12 47.2 0.0 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KLO07649.1 - 5.4e-05 23.0 3.3 0.0099 15.6 1.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Brucella_OMP2 PF05244.11 KLO07649.1 - 0.16 11.3 5.6 0.033 13.6 1.0 2.1 2 0 0 2 2 2 0 Brucella outer membrane protein 2 tRNA-synt_1d PF00750.19 KLO07650.1 - 4e-94 315.4 5.6 5.7e-54 183.4 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 KLO07650.1 - 5.1e-23 81.5 1.2 1.1e-22 80.5 0.2 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain RNA_pol_Rpb4 PF03874.16 KLO07651.1 - 9.7e-18 64.7 0.2 1.8e-17 63.8 0.2 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 Pkinase PF00069.25 KLO07652.1 - 7.2e-39 133.7 0.0 1e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO07652.1 - 1.8e-36 125.8 0.0 2.9e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO07652.1 - 4.8e-06 25.6 0.0 1.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO07652.1 - 0.00029 20.3 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO07652.1 - 0.017 14.7 0.0 0.046 13.3 0.0 1.7 1 0 0 1 1 1 0 RIO1 family p450 PF00067.22 KLO07653.1 - 2.2e-53 181.6 0.0 2.7e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KLO07655.1 - 1.4e-28 100.0 0.0 1.7e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO07655.1 - 2e-13 50.6 0.0 5.9e-13 49.1 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding DUF2559 PF10832.8 KLO07655.1 - 0.0025 17.8 0.3 1.1 9.4 0.0 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF2559) Sacchrp_dh_NADP PF03435.18 KLO07655.1 - 0.0037 17.5 0.1 0.0073 16.6 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KLO07655.1 - 0.0066 15.5 0.0 0.0095 15.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KLO07655.1 - 0.015 15.4 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KLO07655.1 - 0.023 14.9 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 KLO07655.1 - 0.023 15.5 0.1 0.037 14.8 0.1 1.2 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KLO07655.1 - 0.062 13.9 0.3 0.21 12.2 0.3 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 KLO07655.1 - 0.089 12.9 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 KLO07656.1 - 2e-27 96.3 0.0 2.7e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO07656.1 - 1.7e-12 47.6 0.0 3.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KLO07656.1 - 0.00016 21.7 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KLO07656.1 - 0.0002 21.6 0.0 0.0009 19.5 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KLO07656.1 - 0.0028 17.9 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 KLO07656.1 - 0.0067 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AlaDh_PNT_C PF01262.21 KLO07656.1 - 0.037 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 KLO07657.1 - 5.1e-24 85.1 0.0 6.6e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO07657.1 - 3e-09 37.0 0.0 6.2e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KLO07657.1 - 0.0052 17.1 0.1 0.0084 16.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 KLO07657.1 - 0.0056 16.2 0.1 0.0082 15.7 0.1 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 KLO07657.1 - 0.01 16.1 0.1 0.017 15.4 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 KLO07657.1 - 0.015 14.3 0.1 0.021 13.8 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KLO07657.1 - 0.036 14.1 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Inhibitor_I66 PF16850.5 KLO07660.1 - 7.9e-05 22.6 1.1 0.00011 22.1 1.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I66 Pkinase PF00069.25 KLO07661.1 - 9.9e-41 139.8 0.0 1.4e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO07661.1 - 4.8e-39 134.2 0.0 6.8e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO07661.1 - 0.0005 19.5 0.0 0.00088 18.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like eIF-4B PF06273.11 KLO07661.1 - 0.0037 16.4 0.4 0.0055 15.8 0.4 1.1 1 0 0 1 1 1 1 Plant specific eukaryotic initiation factor 4B Dynamin_N PF00350.23 KLO07662.1 - 3.5e-28 98.8 0.0 1.8e-27 96.4 0.0 2.2 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KLO07662.1 - 9.3e-28 97.3 0.0 4.5e-27 95.0 0.0 1.9 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 KLO07662.1 - 4.8e-10 39.5 0.1 1.4e-09 38.0 0.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KLO07662.1 - 3.1e-06 27.3 0.1 4.3e-05 23.6 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KLO07662.1 - 0.011 16.2 0.0 0.22 11.9 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KLO07662.1 - 0.028 14.2 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain FeoB_N PF02421.18 KLO07662.1 - 0.068 12.7 0.3 1.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.6 KLO07662.1 - 0.14 12.7 0.2 31 5.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain PAH PF02671.21 KLO07663.1 - 4.5e-09 36.3 0.0 9.7e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Paired amphipathic helix repeat Zn_clus PF00172.18 KLO07664.1 - 0.66 10.2 7.8 1 9.5 7.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 KLO07666.1 - 0.03 14.8 1.8 0.06 13.8 1.8 1.5 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family Zn_clus PF00172.18 KLO07666.1 - 0.069 13.3 7.6 0.13 12.4 7.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO07668.1 - 0.53 10.5 9.3 0.88 9.7 9.3 1.4 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sin3a_C PF16879.5 KLO07671.1 - 5.2e-69 233.1 0.7 1.5e-66 225.1 0.0 4.2 3 1 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 KLO07671.1 - 3.1e-38 129.7 8.8 2.1e-18 66.2 0.0 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KLO07671.1 - 1.2e-37 127.8 0.2 3.3e-37 126.5 0.2 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Ku_PK_bind PF08785.11 KLO07671.1 - 0.0067 16.6 0.0 1 9.5 0.0 3.0 2 0 0 2 2 2 1 Ku C terminal domain like SPX PF03105.19 KLO07671.1 - 0.37 10.7 19.1 0.12 12.3 4.7 3.3 3 0 0 3 3 3 0 SPX domain PAH PF02671.21 KLO07672.1 - 3.9e-09 36.5 0.1 6.3e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Paired amphipathic helix repeat PAH PF02671.21 KLO07673.1 - 1.1e-10 41.4 0.1 2.3e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 Paired amphipathic helix repeat GP3_package PF16677.5 KLO07673.1 - 0.045 13.9 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 DNA-packaging protein gp3 Ku_PK_bind PF08785.11 KLO07673.1 - 0.18 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Ku C terminal domain like F-box-like PF12937.7 KLO07674.1 - 3.8e-08 33.1 0.5 7.9e-08 32.1 0.5 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO07674.1 - 0.13 12.8 2.7 18 5.9 0.1 3.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KLO07674.1 - 0.14 12.1 4.6 3.9 7.5 0.1 2.9 2 0 0 2 2 2 0 F-box domain Zn_clus PF00172.18 KLO07675.1 - 1 9.6 8.0 1.5 9.0 8.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KLO07676.1 - 1.6e-30 106.3 0.0 1.9e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Imm27 PF15590.6 KLO07677.1 - 0.067 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 27 zf-MYND PF01753.18 KLO07678.1 - 1.1e-10 41.4 14.9 1.8e-10 40.7 14.9 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO07678.1 - 0.0098 16.0 10.4 0.02 15.0 10.4 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 KLO07678.1 - 0.85 9.6 8.3 1.5 8.8 8.3 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-DNA_Pol PF08996.10 KLO07681.1 - 0.059 13.1 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-C2H2_4 PF13894.6 KLO07681.1 - 0.059 14.2 0.8 0.059 14.2 0.8 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Mss51 PF13824.6 KLO07681.1 - 0.076 13.1 4.4 0.062 13.4 2.2 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-Di19 PF05605.12 KLO07681.1 - 0.12 12.6 3.4 0.41 11.0 3.4 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KLO07681.1 - 0.3 11.6 3.0 0.39 11.3 1.2 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-MYND PF01753.18 KLO07682.1 - 1.9e-08 34.2 12.7 1.9e-08 34.2 12.7 1.8 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 KLO07682.1 - 0.76 9.9 4.6 2.2 8.5 4.6 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO07683.1 - 1.9e-08 34.3 12.4 3.9e-08 33.3 12.4 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO07683.1 - 1.2 9.2 4.4 2.8 8.1 4.4 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO07684.1 - 4.1e-10 39.6 8.6 4.1e-10 39.6 8.6 2.1 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 KLO07684.1 - 0.0037 17.3 2.0 0.0092 16.1 2.0 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 p450 PF00067.22 KLO07685.1 - 2.1e-63 214.7 0.0 3.8e-63 213.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO07686.1 - 3.1e-58 197.6 0.0 5.5e-58 196.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO07687.1 - 4.5e-64 216.9 0.0 5.6e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Allatostatin PF05953.12 KLO07687.1 - 0.28 11.9 2.0 0.43 11.3 0.3 2.3 2 0 0 2 2 2 0 Allatostatin p450 PF00067.22 KLO07688.1 - 0.064 12.0 0.0 0.3 9.8 0.0 1.8 2 0 0 2 2 2 0 Cytochrome P450 p450 PF00067.22 KLO07689.1 - 1.4e-52 179.0 0.0 1.7e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-CCHC PF00098.23 KLO07690.1 - 0.00052 20.0 2.5 0.00078 19.4 2.5 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 KLO07690.1 - 0.0034 17.6 0.9 0.044 14.1 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4763 PF15960.5 KLO07690.1 - 0.05 12.9 0.7 0.096 12.0 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) zf-CCHC_3 PF13917.6 KLO07690.1 - 0.061 13.3 1.0 0.11 12.5 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 KLO07693.1 - 5e-05 23.3 0.3 8.2e-05 22.6 0.3 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain p450 PF00067.22 KLO07695.1 - 8.6e-68 229.1 0.0 1.1e-67 228.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lipase_3 PF01764.25 KLO07696.1 - 1.4e-14 54.2 0.0 2.8e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 KLO07696.1 - 0.066 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.22 KLO07697.1 - 5.1e-43 147.5 0.0 2.1e-23 82.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Glutaredoxin PF00462.24 KLO07698.1 - 1.1e-18 67.2 0.0 1.6e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KLO07698.1 - 0.00082 19.8 0.2 0.0013 19.2 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain DUF3228 PF11539.8 KLO07698.1 - 0.0011 18.5 0.0 0.0012 18.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) DUF836 PF05768.14 KLO07698.1 - 0.0025 18.2 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 KLO07698.1 - 0.0045 17.0 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain GST_N_3 PF13417.6 KLO07698.1 - 0.0074 16.7 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 KLO07698.1 - 0.013 15.3 0.2 0.17 11.6 0.1 2.0 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.6 KLO07698.1 - 0.035 13.9 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF953 PF06110.11 KLO07698.1 - 0.035 13.7 0.0 0.16 11.6 0.0 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF953) TraF PF13728.6 KLO07698.1 - 0.063 13.1 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 KLO07698.1 - 0.12 12.5 0.9 3 8.0 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin F-box-like PF12937.7 KLO07699.1 - 5e-06 26.3 0.1 2.8e-05 23.9 0.1 2.2 1 1 0 1 1 1 1 F-box-like LRR_9 PF14580.6 KLO07700.1 - 0.24 10.9 1.0 0.72 9.3 0.2 2.1 1 1 1 2 2 2 0 Leucine-rich repeat F-box-like PF12937.7 KLO07701.1 - 4.6e-06 26.4 0.3 4.6e-05 23.2 0.3 2.5 1 1 0 1 1 1 1 F-box-like LRR_9 PF14580.6 KLO07701.1 - 0.016 14.7 0.9 2.2 7.7 0.0 2.9 2 1 1 3 3 3 0 Leucine-rich repeat LRR_4 PF12799.7 KLO07701.1 - 5.5 7.6 8.8 29 5.2 0.6 4.5 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO07702.1 - 1.6e-06 27.9 1.5 0.012 15.5 1.4 2.7 2 0 0 2 2 2 2 F-box-like F-box-like PF12937.7 KLO07703.1 - 0.00053 19.8 0.2 0.0025 17.7 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO07704.1 - 1.9e-07 30.9 0.3 6.7e-07 29.1 0.3 2.0 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO07705.1 - 0.00022 21.1 6.1 0.00033 20.5 2.9 2.9 2 2 0 2 2 2 1 F-box-like Ribonuc_L-PSP PF01042.21 KLO07706.1 - 4.4e-30 104.2 0.0 4.8e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP zf-C3HC4 PF00097.25 KLO07707.1 - 6.6e-10 38.7 11.2 1.3e-09 37.8 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO07707.1 - 9.3e-09 35.0 6.6 1.6e-08 34.3 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO07707.1 - 2e-08 33.9 10.1 2.9e-08 33.4 9.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO07707.1 - 1e-07 32.1 10.5 1.9e-07 31.3 10.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KLO07707.1 - 6.1e-07 29.4 11.5 2.4e-06 27.5 5.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KLO07707.1 - 2.7e-05 24.0 9.4 5e-05 23.2 9.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KLO07707.1 - 0.00021 21.4 11.7 0.00041 20.5 11.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KLO07707.1 - 0.00026 20.8 8.0 0.00072 19.4 8.2 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KLO07707.1 - 0.004 17.4 5.5 0.0087 16.3 5.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KLO07707.1 - 0.016 15.0 4.9 0.036 13.9 4.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TerY_C PF15616.6 KLO07707.1 - 0.16 12.1 3.8 0.3 11.2 3.8 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-ANAPC11 PF12861.7 KLO07707.1 - 0.17 11.9 3.1 0.31 11.1 3.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ribosomal_S19 PF00203.21 KLO07707.1 - 0.19 11.6 0.2 0.37 10.7 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein S19 zf-MIZ PF02891.20 KLO07707.1 - 0.64 9.8 8.4 1.3 8.8 8.4 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 KLO07707.1 - 1.1 9.0 12.5 2.2 8.1 4.6 2.6 2 0 0 2 2 2 0 RING-like zinc finger DUF1840 PF08895.11 KLO07707.1 - 2.8 8.3 5.7 4.3 7.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) zf-RING_10 PF16685.5 KLO07707.1 - 3.2 8.0 7.7 6.3 7.0 7.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF5127 PF17168.4 KLO07710.1 - 2e-54 184.8 1.1 3.3e-54 184.1 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO07710.1 - 1.4e-48 164.8 0.2 2.4e-47 160.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO07710.1 - 1.5e-29 103.6 0.1 3.6e-29 102.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO07710.1 - 0.0004 19.9 0.1 0.00087 18.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KLO07710.1 - 0.067 12.4 0.0 0.26 10.5 0.0 1.9 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF5127 PF17168.4 KLO07711.1 - 7.3e-49 166.6 2.9 1.5e-48 165.6 2.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KLO07711.1 - 2.3e-46 158.3 0.1 5.3e-46 157.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KLO07711.1 - 2e-43 148.0 1.8 4.6e-43 146.9 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) CD34_antigen PF06365.12 KLO07711.1 - 0.0016 18.1 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Bac_rhamnosid6H PF17389.2 KLO07711.1 - 0.028 13.7 0.0 0.097 11.9 0.0 1.7 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF4964 PF16334.5 KLO07711.1 - 0.091 12.3 0.0 0.31 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) DUF5127 PF17168.4 KLO07712.1 - 1.9e-51 175.0 0.0 1.4e-50 172.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO07712.1 - 1.4e-46 158.3 0.4 2.5e-46 157.5 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO07712.1 - 4.6e-38 131.3 0.1 1.3e-37 129.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO07712.1 - 6e-08 32.1 0.1 1.4e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KLO07712.1 - 0.048 13.1 0.1 0.084 12.3 0.1 1.3 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF5127 PF17168.4 KLO07713.1 - 3.6e-52 177.4 6.5 3.6e-52 177.4 6.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO07713.1 - 1.2e-47 161.8 1.0 2e-47 161.1 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO07713.1 - 1.2e-39 136.5 0.0 2.6e-39 135.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO07713.1 - 5.3e-06 25.9 0.1 1.3e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) F-box-like PF12937.7 KLO07714.1 - 0.00047 20.0 0.2 0.0013 18.5 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO07716.1 - 2.2e-07 30.7 0.2 9.2e-07 28.7 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO07716.1 - 0.05 13.5 1.6 1.1 9.2 0.5 3.2 2 1 0 2 2 2 0 F-box domain CBF PF03914.17 KLO07716.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 CBF/Mak21 family F-box-like PF12937.7 KLO07719.1 - 3.4e-09 36.5 0.2 1e-08 34.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO07719.1 - 0.00041 20.1 0.5 0.93 9.5 0.2 3.0 2 0 0 2 2 2 2 F-box domain LRR_4 PF12799.7 KLO07719.1 - 0.00095 19.5 3.1 17 6.0 0.0 4.8 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) RPT PF13446.6 KLO07719.1 - 0.51 10.3 3.1 41 4.2 0.0 3.2 3 0 0 3 3 3 0 A repeated domain in UCH-protein BTB PF00651.31 KLO07721.1 - 7.1e-06 26.2 0.0 2.9e-05 24.2 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain DUF3875 PF12991.7 KLO07721.1 - 0.026 14.5 0.0 0.15 12.0 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3875) BTB PF00651.31 KLO07722.1 - 0.00014 22.0 0.2 0.0006 20.0 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO07723.1 - 0.00027 21.1 0.0 0.0012 19.0 0.0 2.0 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO07724.1 - 1.9e-05 24.8 0.1 0.0016 18.7 0.0 2.5 2 1 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 KLO07725.1 - 0.00099 19.3 0.3 0.021 15.1 0.0 2.8 2 2 0 2 2 2 1 BTB/POZ domain DUF919 PF06034.11 KLO07725.1 - 0.03 14.1 0.2 0.059 13.2 0.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) ocr PF08684.10 KLO07725.1 - 0.058 13.9 0.2 3.7 8.0 0.0 2.3 2 0 0 2 2 2 0 DNA mimic ocr BTB PF00651.31 KLO07726.1 - 0.0044 17.2 0.3 0.02 15.1 0.0 2.2 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO07727.1 - 0.0062 16.8 0.0 0.026 14.8 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO07728.1 - 0.0014 18.8 0.0 0.0039 17.4 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07729.1 - 0.011 16.0 0.0 0.066 13.4 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain BTB PF00651.31 KLO07730.1 - 0.012 15.8 0.1 0.045 14.0 0.1 2.0 1 1 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 KLO07731.1 - 0.00041 20.6 0.0 0.0018 18.5 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO07732.1 - 0.00086 19.5 0.1 0.0037 17.5 0.1 2.1 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07733.1 - 0.0021 18.2 0.1 0.019 15.2 0.0 2.3 2 1 1 3 3 3 1 BTB/POZ domain BTB PF00651.31 KLO07734.1 - 0.00079 19.6 0.3 0.017 15.3 0.0 2.5 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO07735.1 - 0.0049 17.1 0.0 0.013 15.7 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07736.1 - 0.0055 16.9 0.1 0.0072 16.5 0.1 1.4 1 1 0 1 1 1 1 BTB/POZ domain Retrotrans_gag PF03732.17 KLO07738.1 - 3e-06 27.4 0.3 6.5e-06 26.3 0.3 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Lipase_3 PF01764.25 KLO07740.1 - 3.4e-22 78.9 0.0 4.8e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KLO07740.1 - 0.00011 22.9 0.1 0.00014 22.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO07740.1 - 0.02 14.5 0.0 0.04 13.5 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold BTB PF00651.31 KLO07741.1 - 3.1e-07 30.6 0.1 1.5e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO07742.1 - 1e-06 28.9 0.0 4.1e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07743.1 - 1.9e-06 28.1 0.1 4.9e-06 26.7 0.1 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07744.1 - 3.1e-05 24.2 0.0 0.0001 22.5 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07745.1 - 2.5e-05 24.4 0.0 5.7e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07747.1 - 6.6e-05 23.1 0.2 0.00018 21.7 0.2 1.9 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO07748.1 - 2.9e-05 24.3 0.0 8.2e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain DUF4419 PF14388.6 KLO07749.1 - 4.9e-70 236.3 0.0 5.7e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) GPI-anchored PF10342.9 KLO07750.1 - 0.00022 21.9 1.1 0.00043 21.0 1.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKG6 PF08693.10 KLO07750.1 - 0.021 14.2 0.1 0.035 13.5 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FXMRP1_C_core PF12235.8 KLO07750.1 - 0.13 12.9 1.9 0.35 11.5 1.9 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal HAMP PF00672.25 KLO07752.1 - 1.7e-41 140.4 20.9 2.7e-07 30.9 0.6 9.1 8 1 1 9 9 8 7 HAMP domain HATPase_c PF02518.26 KLO07752.1 - 2.2e-29 102.2 0.2 5.5e-29 100.9 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KLO07752.1 - 5.7e-23 81.2 1.6 1.8e-22 79.6 0.1 2.8 4 0 0 4 4 4 1 Response regulator receiver domain HisKA PF00512.25 KLO07752.1 - 2.4e-17 62.7 1.1 1.2e-16 60.5 1.1 2.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF4795 PF16043.5 KLO07752.1 - 0.00036 20.2 0.1 2.6 7.6 0.0 3.6 2 1 2 4 4 4 2 Domain of unknown function (DUF4795) DUF3829 PF12889.7 KLO07752.1 - 0.017 14.6 0.6 11 5.4 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3829) DUF1843 PF08898.10 KLO07752.1 - 0.018 15.5 10.1 32 5.1 0.0 7.0 7 1 0 7 7 7 0 Domain of unknown function (DUF1843) PurA PF04845.13 KLO07752.1 - 0.04 13.3 0.2 3 7.1 0.0 2.8 2 1 1 3 3 3 0 PurA ssDNA and RNA-binding protein Baculo_PEP_C PF04513.12 KLO07752.1 - 0.041 13.9 37.2 2 8.5 0.6 7.0 1 1 6 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus BORCS6 PF10157.9 KLO07752.1 - 0.92 9.7 14.4 1.7 8.9 0.1 5.6 4 2 1 5 5 5 0 BLOC-1-related complex sub-unit 6 T4SS PF07996.11 KLO07752.1 - 5 7.5 8.2 30 4.9 0.4 3.1 2 1 0 2 2 2 0 Type IV secretion system proteins REF PF05755.12 KLO07752.1 - 7.2 6.4 10.4 12 5.7 0.1 4.2 3 2 1 5 5 5 0 Rubber elongation factor protein (REF) DUF368 PF04018.13 KLO07756.1 - 0.014 15.0 3.0 0.013 15.1 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF368) APT PF03440.14 KLO07756.1 - 0.084 12.8 0.1 0.25 11.3 0.1 1.7 1 1 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain DUF4133 PF13571.6 KLO07756.1 - 2.7 8.4 7.9 3.2 8.1 2.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) ThrE PF06738.12 KLO07760.1 - 5e-52 176.7 20.0 7.2e-51 172.9 7.3 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KLO07760.1 - 3.8e-09 36.8 4.8 3.8e-09 36.8 4.8 2.5 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE CCDC106 PF15794.5 KLO07760.1 - 0.0068 16.2 0.5 0.0068 16.2 0.5 3.7 4 0 0 4 4 4 2 Coiled-coil domain-containing protein 106 RR_TM4-6 PF06459.12 KLO07760.1 - 0.59 9.9 11.0 7.2 6.3 0.1 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3381 PF11861.8 KLO07760.1 - 0.77 9.5 14.6 1.2 8.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Tim54 PF11711.8 KLO07760.1 - 1.2 7.8 7.0 1 8.1 1.4 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Med19 PF10278.9 KLO07760.1 - 3.3 7.6 25.8 1 9.3 12.0 2.5 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 PLDc PF00614.22 KLO07761.1 - 1.3e-17 63.1 2.8 1.2e-09 37.9 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KLO07761.1 - 1.7e-16 60.3 0.0 1.1e-06 28.6 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain Rotamase_3 PF13616.6 KLO07763.1 - 0.095 13.3 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain Rotamase PF00639.21 KLO07763.1 - 0.19 12.7 0.0 0.42 11.6 0.0 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain WaaY PF06176.11 KLO07766.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) NAD_binding_9 PF13454.6 KLO07767.1 - 0.00043 20.3 0.0 0.00068 19.7 0.0 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding FSH1 PF03959.13 KLO07769.1 - 7.2e-48 163.0 0.0 1.1e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 KLO07769.1 - 0.00017 21.2 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KLO07769.1 - 0.00041 20.1 0.4 0.16 11.6 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO07769.1 - 0.016 14.5 0.3 0.19 11.0 0.0 2.5 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KLO07769.1 - 0.023 14.1 0.0 0.91 8.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KLO07769.1 - 0.12 12.2 0.7 0.6 9.9 0.3 2.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Tmemb_14 PF03647.13 KLO07769.1 - 0.15 12.8 0.3 0.31 11.8 0.3 1.4 1 0 0 1 1 1 0 Transmembrane proteins 14C p450 PF00067.22 KLO07770.1 - 2.1e-66 224.6 0.0 2.8e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CSN5_C PF18323.1 KLO07771.1 - 1.2e-29 103.0 6.6 2e-29 102.3 6.6 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain JAB PF01398.21 KLO07771.1 - 8e-29 100.0 0.2 8e-29 100.0 0.2 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KLO07771.1 - 8.2e-06 25.6 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain STAG PF08514.11 KLO07771.1 - 0.016 15.1 0.6 0.031 14.2 0.6 1.4 1 0 0 1 1 1 0 STAG domain DUF4404 PF14357.6 KLO07771.1 - 0.044 14.4 3.3 0.081 13.6 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) UPF0172 PF03665.13 KLO07771.1 - 0.079 13.0 1.7 0.083 12.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Peptidase_S9 PF00326.21 KLO07772.1 - 4.8e-35 121.0 0.0 8.9e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KLO07772.1 - 4.7e-10 39.1 0.2 7e-05 22.2 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KLO07772.1 - 1.4e-07 31.4 0.6 0.0038 16.9 0.2 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KLO07772.1 - 4.1e-06 26.5 0.1 1.2e-05 24.9 0.0 1.7 1 1 1 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KLO07772.1 - 8.1e-06 26.6 0.2 3.4e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KLO07772.1 - 0.0034 17.3 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KLO07772.1 - 0.029 14.5 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 KLO07772.1 - 0.034 13.8 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 KLO07772.1 - 0.06 13.3 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2920 PF11144.8 KLO07772.1 - 0.18 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Antimicrobial23 PF16048.5 KLO07773.1 - 2.1 8.1 3.9 1.8 8.3 0.9 2.2 2 0 0 2 2 2 0 Frog antimicrobial peptide IMS PF00817.20 KLO07775.1 - 8.6e-43 145.9 0.1 1.7e-42 144.9 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KLO07775.1 - 2.6e-12 47.5 0.0 1.1e-11 45.5 0.0 2.1 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 KLO07775.1 - 0.00063 19.1 1.7 0.0031 16.9 0.9 2.3 2 0 0 2 2 2 1 Ubiquitin binding region IMS_HHH PF11798.8 KLO07775.1 - 0.0012 19.1 0.1 0.0057 16.9 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif DUF1805 PF08827.11 KLO07775.1 - 0.0097 16.2 0.1 0.2 12.0 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1805) Zn_clus PF00172.18 KLO07777.1 - 0.091 12.9 12.6 0.16 12.1 12.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DGF-1_C PF11040.8 KLO07778.1 - 0.57 10.2 3.3 1.6 8.8 0.8 2.2 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Ribonucleas_3_3 PF14622.6 KLO07780.1 - 2.8e-11 43.7 0.0 7.8e-11 42.2 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease-III-like FSH1 PF03959.13 KLO07781.1 - 2.8e-45 154.6 0.0 3.7e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KLO07781.1 - 0.00036 21.2 0.0 0.00094 19.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO07781.1 - 0.00062 19.5 0.1 1.1 8.8 0.0 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KLO07781.1 - 0.00079 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KLO07781.1 - 0.022 14.0 0.1 1.8 7.7 0.0 2.5 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Cas_GSU0054 PF09609.10 KLO07781.1 - 0.13 10.9 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) TPR_10 PF13374.6 KLO07784.1 - 1.7e-41 138.9 43.4 3.5e-06 26.7 0.1 12.9 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_12 PF13424.6 KLO07784.1 - 1.1e-31 108.9 27.2 0.0039 17.5 1.8 11.7 9 1 2 11 11 11 9 Tetratricopeptide repeat DUF4404 PF14357.6 KLO07784.1 - 1.7e-13 51.0 14.6 0.4 11.3 0.0 10.4 10 1 1 11 11 9 2 Domain of unknown function (DUF4404) AAA_16 PF13191.6 KLO07784.1 - 1.8e-09 38.2 0.2 4.6e-08 33.6 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain TPR_8 PF13181.6 KLO07784.1 - 2.5e-09 36.6 9.4 3.4 8.1 0.0 8.4 8 0 0 8 8 7 1 Tetratricopeptide repeat DUF3856 PF12968.7 KLO07784.1 - 1.4e-07 31.7 16.9 0.016 15.3 0.5 5.9 4 1 1 6 6 6 3 Domain of Unknown Function (DUF3856) TPR_1 PF00515.28 KLO07784.1 - 1.5e-07 30.9 3.9 9.4 6.2 0.1 7.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KLO07784.1 - 1.5e-06 28.2 26.2 1.1 9.8 0.2 10.1 11 0 0 11 11 8 2 Tetratricopeptide repeat Sec16_C PF12931.7 KLO07784.1 - 3.1e-06 27.1 1.5 1.2 8.8 0.0 4.5 1 1 3 5 5 5 3 Sec23-binding domain of Sec16 ANAPC5 PF12862.7 KLO07784.1 - 0.00015 21.8 20.0 3.8 7.7 0.1 8.8 4 2 4 9 9 9 1 Anaphase-promoting complex subunit 5 Peptidase_M16 PF00675.20 KLO07784.1 - 0.0013 18.7 3.7 1.2 9.2 0.0 4.7 2 1 2 4 4 4 1 Insulinase (Peptidase family M16) NB-ARC PF00931.22 KLO07784.1 - 0.0018 17.5 0.0 0.51 9.5 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 KLO07784.1 - 0.0042 17.4 0.1 1.3 9.3 0.0 4.3 3 2 0 4 4 4 1 AAA domain TPR_11 PF13414.6 KLO07784.1 - 0.012 15.3 1.4 33 4.3 0.0 5.1 5 0 0 5 5 5 0 TPR repeat NACHT PF05729.12 KLO07784.1 - 0.015 15.2 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KLO07784.1 - 0.026 15.1 0.0 0.13 12.8 0.0 2.3 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 KLO07784.1 - 0.026 14.4 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA PF00004.29 KLO07784.1 - 0.07 13.6 0.0 0.23 11.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_7 PF13176.6 KLO07784.1 - 0.077 13.1 22.0 26 5.1 0.0 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat Rad17 PF03215.15 KLO07784.1 - 0.14 12.1 0.0 0.44 10.4 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain DUF2075 PF09848.9 KLO07784.1 - 0.16 11.2 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TPR_2 PF07719.17 KLO07784.1 - 0.2 11.9 15.8 14 6.1 0.1 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat HisKA_2 PF07568.12 KLO07784.1 - 0.27 11.4 2.0 18 5.5 0.0 4.1 4 0 0 4 4 4 0 Histidine kinase PUL PF08324.11 KLO07784.1 - 0.27 10.4 19.7 6.2 6.0 5.9 4.1 1 1 2 3 3 3 0 PUL domain HBM PF16591.5 KLO07784.1 - 1.8 7.9 6.3 1.6 8.1 0.2 3.9 5 0 0 5 5 5 0 Helical bimodular sensor domain UPF0020 PF01170.18 KLO07784.1 - 3.1 7.4 4.8 95 2.6 0.0 4.7 6 0 0 6 6 6 0 Putative RNA methylase family UPF0020 Sugar_tr PF00083.24 KLO07785.1 - 2e-117 392.8 26.8 2.6e-116 389.2 26.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO07785.1 - 1.9e-15 56.7 51.2 1.7e-11 43.7 21.1 2.9 1 1 1 3 3 3 2 Major Facilitator Superfamily DUF2530 PF10745.9 KLO07785.1 - 0.43 10.9 11.7 0.063 13.5 3.7 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) DUF4293 PF14126.6 KLO07785.1 - 1.2 9.4 5.2 1.1 9.5 1.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) p450 PF00067.22 KLO07786.1 - 1.8e-71 241.3 0.0 2.2e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.18 KLO07787.1 - 5.8e-09 35.8 0.2 8.5e-08 32.0 0.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) F-box-like PF12937.7 KLO07788.1 - 0.0041 17.0 0.7 0.024 14.5 0.0 2.6 3 0 0 3 3 3 1 F-box-like Cep57_CLD_2 PF14197.6 KLO07788.1 - 0.43 10.7 1.6 0.92 9.6 1.6 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF1708 PF08101.11 KLO07791.1 - 7.7e-21 74.7 0.0 2.2e-17 63.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 KLO07791.1 - 0.00027 20.8 0.0 0.00061 19.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Tetraspanin PF00335.20 KLO07793.1 - 1.7e-08 34.5 12.1 2.9e-08 33.7 12.0 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF2207 PF09972.9 KLO07793.1 - 0.16 10.7 1.2 0.2 10.4 0.6 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Furin-like_2 PF15913.5 KLO07794.1 - 9.7e-05 22.5 16.6 9.7e-05 22.5 16.6 6.5 1 1 6 7 7 7 3 Furin-like repeat, cysteine-rich VSP PF03302.13 KLO07794.1 - 0.00055 18.9 34.5 0.00055 18.9 34.5 6.1 1 1 5 6 6 6 5 Giardia variant-specific surface protein EGF_2 PF07974.13 KLO07794.1 - 0.0035 17.7 13.1 0.0035 17.7 13.1 12.8 11 3 1 12 12 12 2 EGF-like domain DUF4381 PF14316.6 KLO07794.1 - 0.72 10.1 3.5 1.3 9.3 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Metallophos PF00149.28 KLO07795.1 - 4.3e-37 128.6 0.2 6.1e-37 128.1 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KLO07795.1 - 0.0016 18.8 0.4 0.0033 17.8 0.4 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KLO07795.1 - 0.029 14.0 0.0 0.042 13.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Pro_isomerase PF00160.21 KLO07797.1 - 3e-48 164.1 0.0 3.4e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3759 PF12585.8 KLO07800.1 - 3.1 7.9 5.0 1.4 9.0 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3759) PIN_6 PF17146.4 KLO07801.1 - 0.063 13.8 0.1 0.35 11.4 0.1 2.1 1 1 0 1 1 1 0 PIN domain of ribonuclease NtCtMGAM_N PF16863.5 KLO07801.1 - 0.082 13.1 0.2 0.17 12.1 0.2 1.5 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase MAD PF05557.13 KLO07802.1 - 4.2e-48 164.2 37.2 9.1e-47 159.8 20.2 3.2 2 1 0 2 2 2 2 Mitotic checkpoint protein Pox_A_type_inc PF04508.12 KLO07802.1 - 7.7e-07 28.7 21.3 0.028 14.3 0.1 7.9 7 0 0 7 7 7 3 Viral A-type inclusion protein repeat ATG16 PF08614.11 KLO07802.1 - 8e-06 26.2 85.7 0.0045 17.2 5.4 7.1 4 3 2 6 6 6 4 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 KLO07802.1 - 0.0023 17.7 50.5 0.013 15.2 1.0 6.9 6 1 1 7 7 7 3 Domain of unknown function (DUF4201) APG6_N PF17675.1 KLO07802.1 - 0.0024 18.4 4.2 0.0024 18.4 4.2 8.0 6 2 2 8 8 7 2 Apg6 coiled-coil region DUF4407 PF14362.6 KLO07802.1 - 0.0048 16.3 44.7 0.12 11.8 11.7 4.4 2 1 1 3 3 2 2 Domain of unknown function (DUF4407) Cep57_CLD_2 PF14197.6 KLO07802.1 - 0.0053 16.8 2.9 0.0053 16.8 2.9 9.2 8 3 0 8 8 6 2 Centrosome localisation domain of PPC89 BRE1 PF08647.11 KLO07802.1 - 0.023 14.8 1.1 0.023 14.8 1.1 7.4 6 3 1 7 7 7 0 BRE1 E3 ubiquitin ligase Spidroin_N PF16763.5 KLO07802.1 - 0.041 13.9 1.8 0.11 12.6 0.0 2.5 2 1 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term Atg14 PF10186.9 KLO07802.1 - 0.055 12.6 58.2 0.28 10.2 6.1 5.5 4 2 2 6 6 6 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 KLO07802.1 - 0.073 13.4 0.3 0.073 13.4 0.3 5.8 6 2 1 7 7 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4763 PF15960.5 KLO07802.1 - 0.079 12.3 0.2 0.079 12.3 0.2 6.7 6 3 0 6 6 4 0 Domain of unknown function (DUF4763) PhdYeFM_antitox PF02604.19 KLO07802.1 - 0.12 12.2 2.8 0.43 10.4 0.2 3.4 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system NleF_casp_inhib PF16809.5 KLO07802.1 - 0.12 12.3 7.1 4.4 7.2 0.2 3.5 2 1 1 3 3 3 0 NleF caspase inhibitor Phage_GP20 PF06810.11 KLO07802.1 - 0.13 12.0 37.8 0.85 9.4 0.4 6.6 5 2 1 6 6 6 0 Phage minor structural protein GP20 YabA PF06156.13 KLO07802.1 - 0.19 12.4 0.1 0.19 12.4 0.1 7.9 6 3 1 7 7 7 0 Initiation control protein YabA VGPC1_C PF16799.5 KLO07802.1 - 0.25 11.4 4.8 3.2 7.8 0.3 3.9 3 0 0 3 3 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 CENP-F_leu_zip PF10473.9 KLO07802.1 - 0.93 9.5 65.0 0.11 12.5 4.2 7.2 6 1 0 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 KLO07802.1 - 0.97 9.7 59.3 0.32 11.2 1.5 7.2 5 2 1 7 7 7 0 TATA element modulatory factor 1 TATA binding TACC_C PF05010.14 KLO07802.1 - 1.3 8.8 45.9 1.2 8.9 2.1 6.6 5 1 1 6 6 6 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Tho2 PF11262.8 KLO07802.1 - 1.5 8.0 0.0 1.5 8.0 0.0 5.4 5 2 1 6 6 6 0 Transcription factor/nuclear export subunit protein 2 UPF0242 PF06785.11 KLO07802.1 - 1.9 8.5 46.8 0.63 10.1 3.2 5.4 3 2 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 KLO07802.1 - 2.4 8.6 58.4 18 5.7 13.0 5.7 2 2 2 4 4 3 0 Fez1 Fib_alpha PF08702.10 KLO07802.1 - 4.8 7.4 30.4 4 7.6 0.8 6.4 5 1 0 6 6 6 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 KLO07802.1 - 6.9 6.5 41.2 0.09 12.6 1.6 5.6 5 1 0 5 5 5 0 Protein of unknown function (DUF724) PHM7_cyt PF14703.6 KLO07802.1 - 7 6.9 13.0 5.4 7.2 0.8 4.3 2 1 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter DASH_Dam1 PF08653.10 KLO07802.1 - 7.1 6.5 8.0 41 4.1 0.1 4.6 5 0 0 5 5 5 0 DASH complex subunit Dam1 DUF4988 PF16378.5 KLO07802.1 - 7.6 6.2 6.3 6.8 6.3 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function DUF5320 PF17253.2 KLO07802.1 - 7.8 7.6 19.8 26 6.0 0.3 6.1 5 2 1 6 6 5 0 Family of unknown function (DUF5320) NPV_P10 PF05531.12 KLO07802.1 - 10 6.7 23.4 1.2 9.6 0.4 5.7 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein NIF PF03031.18 KLO07803.1 - 2.8e-11 43.4 0.0 6.5e-10 39.0 0.0 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase VIT PF08487.10 KLO07803.1 - 0.14 12.4 0.5 0.27 11.4 0.5 1.4 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Plasmodium_Vir PF05795.11 KLO07803.1 - 0.32 10.4 4.4 0.88 8.9 4.4 1.7 1 1 0 1 1 1 0 Plasmodium vivax Vir protein NACHT PF05729.12 KLO07805.1 - 2.9e-16 59.9 0.7 2.1e-12 47.3 0.0 3.2 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO07805.1 - 7e-14 52.6 0.2 1.1e-05 25.8 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KLO07805.1 - 6.6e-08 32.9 0.0 1.5e-05 25.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KLO07805.1 - 1.8e-05 25.1 0.1 0.00088 19.7 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KLO07805.1 - 8.9e-05 21.7 1.0 0.09 11.9 0.2 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KLO07805.1 - 0.00033 19.9 0.1 0.009 15.2 0.0 2.8 2 1 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 KLO07805.1 - 0.0044 16.9 1.7 0.11 12.4 0.3 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase Torsin PF06309.11 KLO07805.1 - 0.0069 16.5 0.0 7.8 6.6 0.0 3.2 3 0 0 3 3 3 2 Torsin AAA_30 PF13604.6 KLO07805.1 - 0.016 14.9 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KLO07805.1 - 0.021 15.2 0.3 1.5 9.2 0.1 2.8 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KLO07805.1 - 0.026 15.0 0.0 0.38 11.3 0.0 3.1 2 0 0 2 2 2 0 AAA domain Chitin_bind_4 PF00379.23 KLO07806.1 - 0.014 15.9 0.8 0.038 14.5 0.8 1.7 1 0 0 1 1 1 0 Insect cuticle protein NACHT PF05729.12 KLO07807.1 - 1.2e-16 61.1 0.2 9.1e-13 48.5 0.0 2.9 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO07807.1 - 5e-14 53.0 0.0 1.4e-05 25.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Pkinase_Tyr PF07714.17 KLO07807.1 - 8e-12 45.0 0.0 1.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO07807.1 - 5.3e-11 42.4 0.0 9.6e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain AAA_22 PF13401.6 KLO07807.1 - 6.4e-08 33.0 0.0 8.1e-06 26.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 KLO07807.1 - 0.00018 20.7 1.2 0.42 9.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KLO07807.1 - 0.00036 19.8 0.0 0.0079 15.4 0.0 2.9 3 1 0 3 3 3 1 NB-ARC domain AAA PF00004.29 KLO07807.1 - 0.00058 20.3 0.0 0.011 16.2 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KLO07807.1 - 0.0015 18.4 0.0 0.6 10.0 0.0 2.8 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea APS_kinase PF01583.20 KLO07807.1 - 0.0018 18.2 1.3 0.11 12.4 0.2 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase RNA_helicase PF00910.22 KLO07807.1 - 0.0097 16.3 0.1 1 9.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 KLO07807.1 - 0.012 15.4 0.0 0.079 12.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KLO07807.1 - 0.025 15.1 0.0 0.6 10.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain Torsin PF06309.11 KLO07807.1 - 0.025 14.7 0.0 5.2 7.2 0.0 2.7 2 0 0 2 2 2 0 Torsin PIF1 PF05970.14 KLO07807.1 - 0.039 13.1 0.0 0.29 10.3 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase NACHT PF05729.12 KLO07808.1 - 2.6e-18 66.5 1.0 2.2e-12 47.2 0.0 3.5 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO07808.1 - 4.3e-13 50.0 0.5 2.5e-06 28.0 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KLO07808.1 - 5.8e-10 39.6 0.0 5.1e-07 30.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KLO07808.1 - 8.1e-07 29.5 0.1 2.9e-05 24.5 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KLO07808.1 - 3.5e-05 23.0 1.0 0.18 10.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KLO07808.1 - 0.00045 19.5 0.1 0.0089 15.2 0.1 2.8 2 1 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 KLO07808.1 - 0.0015 18.4 0.9 0.16 11.8 0.4 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase KAP_NTPase PF07693.14 KLO07808.1 - 0.0015 17.8 0.0 0.026 13.8 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain Torsin PF06309.11 KLO07808.1 - 0.0023 18.0 0.0 3.9 7.6 0.0 2.8 2 0 0 2 2 2 2 Torsin AAA_30 PF13604.6 KLO07808.1 - 0.0025 17.6 0.0 0.052 13.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KLO07808.1 - 0.0099 16.3 0.3 1.3 9.5 0.1 3.0 3 0 0 3 3 2 1 RNA helicase AAA_18 PF13238.6 KLO07808.1 - 0.018 15.6 2.5 0.19 12.3 0.1 3.8 5 1 0 5 5 3 0 AAA domain AAA_19 PF13245.6 KLO07808.1 - 0.038 14.3 0.1 3.9 7.8 0.1 2.7 2 1 0 2 2 2 0 AAA domain RHH_5 PF07878.11 KLO07808.1 - 0.041 13.8 0.3 25 4.8 0.0 3.7 3 0 0 3 3 3 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Cytidylate_kin PF02224.18 KLO07808.1 - 0.051 13.3 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase PIF1 PF05970.14 KLO07808.1 - 0.086 12.0 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase PhoH PF02562.16 KLO07808.1 - 0.14 11.6 0.0 8.2 5.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein RHH_5 PF07878.11 KLO07809.1 - 0.022 14.6 0.4 0.31 11.0 0.1 2.1 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Parvo_NS1 PF01057.17 KLO07809.1 - 0.041 13.0 0.0 0.043 12.9 0.0 1.0 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Slx4 PF09494.10 KLO07809.1 - 0.089 12.8 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Slx4 endonuclease ATPase_2 PF01637.18 KLO07809.1 - 0.17 11.8 0.0 0.18 11.7 0.0 1.0 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KLO07810.1 - 1.3e-13 51.2 0.1 6e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KLO07810.1 - 8.5e-06 26.1 0.0 2.4e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO07810.1 - 1.1e-05 25.9 0.1 4.3e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Parvo_NS1 PF01057.17 KLO07810.1 - 0.005 16.0 0.1 0.0087 15.2 0.1 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KLO07810.1 - 0.0086 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KLO07810.1 - 0.029 14.7 0.0 0.076 13.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KLO07810.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KLO07810.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein APS_kinase PF01583.20 KLO07810.1 - 0.11 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 KLO07814.1 - 1.8e-16 60.5 0.7 4.9e-13 49.3 0.0 3.0 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO07814.1 - 7e-11 42.8 0.2 5e-05 23.8 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KLO07814.1 - 1.3e-10 41.6 0.0 1.1e-05 25.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain NB-ARC PF00931.22 KLO07814.1 - 8.6e-05 21.8 0.0 0.0023 17.2 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain Parvo_NS1 PF01057.17 KLO07814.1 - 0.00015 21.0 0.7 0.16 11.0 0.2 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA PF00004.29 KLO07814.1 - 0.00064 20.1 0.0 0.012 16.0 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KLO07814.1 - 0.0018 18.2 1.3 0.087 12.7 0.2 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase ATPase_2 PF01637.18 KLO07814.1 - 0.009 15.9 0.0 0.58 10.0 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KLO07814.1 - 0.01 15.6 0.0 0.052 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KLO07814.1 - 0.017 15.5 0.1 1.6 9.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Torsin PF06309.11 KLO07814.1 - 0.024 14.8 0.0 14 5.8 0.0 2.9 2 0 0 2 2 2 0 Torsin AAA_18 PF13238.6 KLO07814.1 - 0.06 13.9 0.0 0.5 10.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KLO07814.1 - 0.1 13.1 0.0 0.35 11.4 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 KLO07814.1 - 0.17 12.2 0.1 0.99 9.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain PIF1 PF05970.14 KLO07814.1 - 0.17 11.0 0.0 0.59 9.2 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase PhoH PF02562.16 KLO07814.1 - 0.2 11.1 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein CPBP PF02517.16 KLO07816.1 - 6.3e-15 55.3 3.9 6.3e-15 55.3 3.9 2.2 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease FUN14 PF04930.15 KLO07816.1 - 0.22 12.0 0.4 0.22 12.0 0.4 1.8 2 0 0 2 2 2 0 FUN14 family F-box-like PF12937.7 KLO07817.1 - 0.015 15.2 0.3 0.082 12.8 0.3 2.4 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 KLO07817.1 - 0.093 13.2 4.1 6.6 7.3 0.8 4.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) NT-C2 PF10358.9 KLO07818.1 - 1e-20 74.0 0.0 5.9e-20 71.5 0.0 2.0 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ribosomal_L28 PF00830.19 KLO07819.1 - 2.7e-21 75.5 0.5 4.1e-21 74.9 0.5 1.3 1 0 0 1 1 1 1 Ribosomal L28 family GWT1 PF06423.12 KLO07820.1 - 9e-40 136.2 0.2 9e-40 136.2 0.2 2.2 2 1 0 2 2 2 1 GWT1 Myb_DNA-binding PF00249.31 KLO07822.1 - 6e-07 29.6 0.1 1e-06 28.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KLO07822.1 - 0.0019 18.4 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4175 PF13779.6 KLO07822.1 - 0.34 8.8 3.9 0.64 7.9 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spectrin PF00435.21 KLO07822.1 - 0.53 10.8 3.7 0.97 9.9 0.9 2.3 2 0 0 2 2 2 0 Spectrin repeat Polysacc_synt_4 PF04669.13 KLO07823.1 - 4.2e-19 68.8 7.0 5.7e-19 68.4 1.4 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis DUF1910 PF08928.10 KLO07823.1 - 0.053 13.5 0.7 0.053 13.5 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) Atg14 PF10186.9 KLO07824.1 - 0.0053 15.9 8.7 0.0086 15.2 8.7 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ERM PF00769.19 KLO07824.1 - 0.15 11.9 29.8 0.023 14.5 25.8 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family HOOK PF05622.12 KLO07824.1 - 0.16 10.1 15.4 0.23 9.6 15.4 1.1 1 0 0 1 1 1 0 HOOK protein Med30 PF11315.8 KLO07824.1 - 0.19 11.9 7.7 0.15 12.3 4.5 2.3 2 1 0 2 2 2 0 Mediator complex subunit 30 ATG16 PF08614.11 KLO07824.1 - 0.2 11.8 26.8 0.076 13.2 23.4 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) COG2 PF06148.11 KLO07824.1 - 4.6 7.3 8.6 4.4 7.4 6.6 1.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GAS PF13851.6 KLO07824.1 - 5.2 6.4 17.9 18 4.6 17.9 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 KLO07824.1 - 8.7 6.6 13.0 1.6 9.0 6.4 2.4 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GIY-YIG PF01541.24 KLO07825.1 - 3.6e-10 40.0 0.0 7.2e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain RNase_II_C_S1 PF18614.1 KLO07825.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain FANCL_C PF11793.8 KLO07825.1 - 0.11 12.7 1.3 0.25 11.5 1.3 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 KLO07825.1 - 0.18 11.9 0.7 0.39 10.9 0.7 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger PHD_4 PF16866.5 KLO07825.1 - 0.41 10.8 1.9 1.3 9.2 1.9 1.9 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KLO07825.1 - 0.45 10.9 3.3 1.2 9.5 1.5 2.4 2 1 0 2 2 2 0 RING-like domain zf-RING_2 PF13639.6 KLO07825.1 - 0.85 10.0 4.9 1.8 8.9 4.9 1.6 1 0 0 1 1 1 0 Ring finger domain SAP PF02037.27 KLO07827.1 - 6.6e-08 32.1 0.9 2.2e-07 30.5 0.7 2.0 2 0 0 2 2 2 1 SAP domain LETM1 PF07766.13 KLO07827.1 - 0.035 13.5 0.2 0.06 12.7 0.2 1.3 1 0 0 1 1 1 0 LETM1-like protein FAM176 PF14851.6 KLO07827.1 - 1.5 8.5 3.6 4.6 6.9 3.6 1.8 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 KLO07827.1 - 9.2 4.4 9.8 17 3.6 9.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S30 PF04758.14 KLO07829.1 - 1.4e-26 92.4 5.7 1.5e-26 92.3 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 CCDC-167 PF15188.6 KLO07830.1 - 0.015 15.7 0.3 0.037 14.4 0.3 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Tropomyosin PF00261.20 KLO07830.1 - 0.046 13.1 1.2 0.097 12.0 1.2 1.4 1 0 0 1 1 1 0 Tropomyosin FMN_dh PF01070.18 KLO07831.1 - 3e-104 348.8 0.0 4.4e-104 348.2 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KLO07831.1 - 1e-05 25.1 0.7 1.6e-05 24.4 0.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KLO07831.1 - 3.7e-05 22.9 0.5 0.00012 21.2 0.1 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KLO07831.1 - 0.00018 20.7 0.2 0.00028 20.2 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KLO07831.1 - 0.0039 16.7 0.5 1.3 8.4 0.1 2.2 1 1 1 2 2 2 2 Histidine biosynthesis protein DHO_dh PF01180.21 KLO07831.1 - 0.0062 15.8 0.1 0.016 14.4 0.1 1.7 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 KLO07831.1 - 0.0077 15.6 0.6 2.4 7.4 0.1 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Pterin_bind PF00809.22 KLO07834.1 - 6.1e-60 202.9 0.2 1.9e-59 201.3 0.0 2.0 2 1 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.20 KLO07834.1 - 4.9e-31 107.6 0.0 1.3e-30 106.2 0.0 1.8 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 KLO07834.1 - 1.1e-27 96.8 0.0 1.9e-16 60.6 0.0 2.7 2 0 0 2 2 2 2 Dihydroneopterin aldolase Glyco_hydro_44 PF12891.7 KLO07834.1 - 0.036 14.0 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycoside hydrolase family 44 HIG_1_N PF04588.13 KLO07835.1 - 5.1e-17 61.8 1.2 7.7e-17 61.3 1.2 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DHHA2 PF02833.14 KLO07836.1 - 1.1e-25 90.5 0.4 3.1e-25 89.0 0.2 1.8 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 KLO07836.1 - 3.3e-12 46.5 0.0 1.7e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 DHH family TPR_14 PF13428.6 KLO07837.1 - 8.3e-09 35.6 4.4 0.0051 17.5 0.3 4.5 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KLO07837.1 - 3.3e-08 34.0 0.5 0.0022 18.6 0.9 3.7 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KLO07837.1 - 6.9e-08 32.0 0.7 0.00075 19.4 0.1 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KLO07837.1 - 3.1e-07 30.1 0.2 0.00018 21.5 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KLO07837.1 - 3.3e-07 30.7 3.2 7e-05 23.3 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KLO07837.1 - 7e-07 28.8 0.2 0.004 16.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KLO07837.1 - 5.7e-06 26.4 3.4 0.043 14.0 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KLO07837.1 - 0.00015 21.5 0.8 0.016 15.2 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KLO07837.1 - 0.0002 21.6 2.3 0.14 12.5 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KLO07837.1 - 0.0011 18.6 0.2 1 9.1 0.0 3.2 3 0 0 3 3 3 1 TPR repeat DUF3856 PF12968.7 KLO07837.1 - 0.09 12.8 1.0 13 5.8 0.1 3.2 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 KLO07837.1 - 0.12 12.9 1.9 29 5.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5601 PF18151.1 KLO07837.1 - 0.12 12.7 0.0 0.4 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) bPH_6 PF10756.9 KLO07837.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial PH domain TPR_6 PF13174.6 KLO07837.1 - 0.15 12.8 0.9 49 4.9 0.1 4.2 6 0 0 6 6 4 0 Tetratricopeptide repeat ChAPs PF09295.10 KLO07837.1 - 0.18 10.7 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) CotJB PF12652.7 KLO07837.1 - 0.41 10.9 2.6 2 8.7 0.1 2.8 2 1 1 3 3 3 0 CotJB protein Complex1_LYR PF05347.15 KLO07838.1 - 1.1e-10 41.4 1.3 1.4e-10 41.1 1.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Peptidase_S24 PF00717.23 KLO07840.1 - 2.6e-08 33.7 0.0 4.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Zn_clus PF00172.18 KLO07843.1 - 0.00044 20.3 9.0 0.00082 19.5 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Git3 PF11710.8 KLO07844.1 - 2.5e-08 34.0 6.5 6.8e-08 32.5 6.5 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KLO07844.1 - 0.0013 18.1 2.9 0.0058 16.0 1.9 2.3 2 1 1 3 3 3 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 KLO07844.1 - 0.11 12.6 3.3 0.11 12.5 0.1 2.5 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 KLO07844.1 - 0.86 8.7 4.5 0.81 8.8 3.2 1.5 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor Zn_clus PF00172.18 KLO07845.1 - 0.00081 19.5 5.4 0.0014 18.7 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MalF_P2 PF14785.6 KLO07845.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Zn_clus PF00172.18 KLO07846.1 - 0.0029 17.7 5.5 0.0043 17.1 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Git3 PF11710.8 KLO07848.1 - 4.6e-07 29.8 10.1 1.6e-06 28.0 10.0 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KLO07848.1 - 1.3e-05 24.7 3.1 7.9e-05 22.1 2.5 2.2 2 1 1 3 3 3 1 7 transmembrane receptor (rhodopsin family) AWPM-19 PF05512.11 KLO07848.1 - 0.16 12.1 4.3 0.31 11.2 4.3 1.4 1 0 0 1 1 1 0 AWPM-19-like family Frag1 PF10277.9 KLO07849.1 - 5.6e-45 153.6 7.1 6.2e-45 153.4 7.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 KLO07849.1 - 3.8e-05 23.4 18.3 6.3e-05 22.7 17.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF998) DUF1294 PF06961.13 KLO07849.1 - 0.16 12.3 2.6 0.16 12.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) DUF3098 PF11297.8 KLO07849.1 - 0.24 11.0 3.9 0.62 9.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) DUF1129 PF06570.11 KLO07849.1 - 0.24 10.8 1.7 0.57 9.6 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Peptidase_U4 PF03419.13 KLO07849.1 - 0.24 10.6 5.1 0.36 10.1 4.6 1.6 1 1 1 2 2 2 0 Sporulation factor SpoIIGA DUF3754 PF12576.8 KLO07849.1 - 2.3 8.2 6.7 0.7 9.8 2.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) DUF2070 PF09843.9 KLO07849.1 - 3.1 6.0 11.1 2.4 6.3 9.9 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4064 PF13273.6 KLO07849.1 - 7.5 6.9 13.9 1.2 9.5 7.4 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF4064) Git3 PF11710.8 KLO07850.1 - 5.2e-07 29.6 5.6 1.2e-06 28.4 5.6 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Citrate_synt PF00285.21 KLO07851.1 - 3e-99 332.5 0.0 3.8e-99 332.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain CoA_trans PF01144.23 KLO07852.1 - 9.9e-97 322.6 1.7 4.9e-57 192.8 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KLO07852.1 - 4.7e-05 23.4 0.1 0.00012 22.1 0.1 1.6 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 KLO07852.1 - 0.011 14.1 0.8 0.023 13.0 0.2 1.7 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hydro PF02550.15 KLO07852.1 - 0.057 13.4 0.2 7.7 6.4 0.0 3.4 4 0 0 4 4 4 0 Acetyl-CoA hydrolase/transferase N-terminal domain FAM153 PF15722.5 KLO07852.1 - 0.21 12.0 0.3 0.7 10.3 0.2 1.9 2 0 0 2 2 2 0 FAM153 family CoA_trans PF01144.23 KLO07853.1 - 1.1e-100 335.6 5.6 5.6e-61 205.7 0.9 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KLO07853.1 - 0.00023 21.1 0.1 0.00046 20.1 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KLO07853.1 - 0.032 14.2 0.0 1.8 8.5 0.0 3.0 3 0 0 3 3 3 0 Acetyl-CoA hydrolase/transferase N-terminal domain DeoRC PF00455.22 KLO07853.1 - 0.13 12.2 0.0 5.2 7.0 0.0 2.6 2 0 0 2 2 2 0 DeoR C terminal sensor domain Herpes_LMP1 PF05297.11 KLO07856.1 - 0.21 10.8 1.0 0.3 10.3 1.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) F-box-like PF12937.7 KLO07857.1 - 2.4e-09 36.9 0.5 6.5e-09 35.6 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO07858.1 - 1.7e-09 37.4 1.7 4.2e-09 36.2 1.7 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO07859.1 - 2e-09 37.2 1.8 2.8e-09 36.7 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KLO07859.1 - 0.21 11.6 0.8 2.6 8.1 0.1 2.9 3 1 0 3 3 3 0 F-box-like domain Gln-synt_C PF00120.24 KLO07860.1 - 9.1e-64 215.6 0.0 1.3e-63 215.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KLO07860.1 - 0.014 15.2 0.0 0.57 10.0 0.0 3.0 2 1 0 2 2 2 0 Glutamine synthetase N-terminal domain F-box-like PF12937.7 KLO07861.1 - 0.0037 17.1 0.1 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 F-box-like BTB PF00651.31 KLO07862.1 - 0.0052 17.0 0.0 0.012 15.9 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain SR1P PF13790.6 KLO07862.1 - 0.075 13.2 0.3 0.19 11.8 0.3 1.7 1 0 0 1 1 1 0 SR1 protein Herpes_IE68 PF02479.16 KLO07862.1 - 0.33 10.6 1.5 0.69 9.5 0.1 1.9 1 1 1 2 2 2 0 Herpesvirus immediate early protein zf-RING_6 PF14835.6 KLO07863.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Aldo_ket_red PF00248.21 KLO07878.1 - 4.9e-70 236.0 0.0 5.7e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Dfp1_Him1_M PF08630.10 KLO07880.1 - 6.9e-18 65.1 0.0 2e-17 63.6 0.0 1.8 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 KLO07880.1 - 2.5e-15 56.3 2.5 4.8e-15 55.4 2.5 1.5 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 KLO07880.1 - 0.0002 21.7 0.0 0.00058 20.2 0.0 1.9 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KLO07880.1 - 0.0068 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain Pkinase_Tyr PF07714.17 KLO07885.1 - 4.3e-22 78.7 0.0 4.7e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO07885.1 - 6.2e-20 71.7 0.0 6.8e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KLO07885.1 - 0.0022 17.4 0.0 0.0028 17.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO07885.1 - 0.0064 16.4 0.0 0.0078 16.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO07885.1 - 0.21 10.9 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KLO07885.1 - 0.23 11.0 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family F-box-like PF12937.7 KLO07887.1 - 3.8e-06 26.7 1.2 6e-06 26.1 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO07889.1 - 1.5e-05 24.8 1.8 3.2e-05 23.7 0.3 2.3 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 KLO07889.1 - 0.067 13.0 4.0 8.9 6.2 0.0 4.1 4 1 0 4 4 4 0 Leucine rich repeat F-box PF00646.33 KLO07889.1 - 0.31 11.0 2.2 0.49 10.3 0.2 2.5 2 0 0 2 2 2 0 F-box domain Asp PF00026.23 KLO07895.1 - 2.6e-12 46.8 0.0 1.1e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease zf-U1 PF06220.12 KLO07898.1 - 6.6e-18 64.2 4.3 9.8e-18 63.7 4.3 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.8 KLO07898.1 - 0.65 10.4 6.1 5.7 7.4 6.1 2.1 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Methyltransf_23 PF13489.6 KLO07900.1 - 4.5e-06 26.6 0.0 7.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO07900.1 - 8e-06 26.5 0.0 1.8e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO07900.1 - 5.6e-05 23.0 0.0 9.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO07900.1 - 0.00045 20.8 0.0 0.001 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO07900.1 - 0.00057 20.5 0.0 0.0014 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO07900.1 - 0.0087 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KLO07900.1 - 0.013 14.1 0.0 0.03 12.9 0.0 1.5 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Peptidase_M48 PF01435.18 KLO07901.1 - 0.02 14.7 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 14-3-3 PF00244.20 KLO07903.1 - 4.1e-80 268.5 0.8 4.6e-80 268.3 0.8 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 KLO07903.1 - 0.35 11.4 5.2 0.39 11.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DALR_1 PF05746.15 KLO07904.1 - 0.24 11.6 1.2 6.7 6.9 1.2 2.1 1 1 0 1 1 1 0 DALR anticodon binding domain RRM_3 PF08777.11 KLO07908.1 - 1.5e-07 31.4 0.0 3.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif RRM_1 PF00076.22 KLO07908.1 - 0.013 15.3 0.1 0.23 11.3 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRF1 PF07741.13 KLO07908.1 - 0.26 11.7 0.1 0.26 11.7 0.1 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF1768 PF08719.11 KLO07909.1 - 9e-23 81.3 0.0 1.1e-22 81.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) SAP18 PF06487.12 KLO07910.1 - 3.3e-32 111.6 0.0 4.3e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) WD40 PF00400.32 KLO07911.1 - 3e-27 94.3 9.0 0.00013 22.7 0.0 7.5 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO07911.1 - 1.9e-13 50.5 0.0 0.00021 21.5 0.0 4.5 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KLO07911.1 - 0.032 14.7 6.5 1.1 9.8 0.0 4.4 5 0 0 5 5 5 0 PQQ-like domain WD40_like PF17005.5 KLO07911.1 - 0.039 13.3 0.0 3.5 6.9 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain Lactonase PF10282.9 KLO07911.1 - 0.088 12.1 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Ge1_WD40 PF16529.5 KLO07911.1 - 0.11 11.4 0.3 6.2 5.7 0.0 2.8 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KLO07911.1 - 0.2 9.9 0.0 0.71 8.1 0.0 1.7 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz HTH_39 PF14090.6 KLO07912.1 - 0.014 15.1 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain SSF PF00474.17 KLO07914.1 - 3.2e-22 78.9 24.4 4.5e-22 78.5 24.4 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family F-box-like PF12937.7 KLO07916.1 - 5e-07 29.5 0.1 2.2e-06 27.4 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO07916.1 - 0.02 14.8 0.2 0.089 12.7 0.2 2.1 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO07917.1 - 0.00033 20.5 0.1 0.00098 19.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KLO07917.1 - 0.034 14.1 1.8 0.12 12.3 0.1 2.6 3 0 0 3 3 3 0 F-box-like domain Acetyltransf_1 PF00583.25 KLO07919.1 - 7.6e-14 52.0 0.1 8.8e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KLO07919.1 - 8.7e-10 38.6 0.2 1e-09 38.4 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO07919.1 - 5.8e-08 33.1 0.1 7.5e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO07919.1 - 0.00025 20.9 0.1 0.00034 20.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KLO07919.1 - 0.00036 20.6 0.1 0.00041 20.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KLO07919.1 - 0.00057 19.4 0.1 0.00081 18.9 0.1 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Abhydrolase_6 PF12697.7 KLO07920.1 - 2.1e-06 28.5 0.3 2.8e-06 28.1 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KLO07920.1 - 5.3e-06 26.1 0.0 1.1e-05 25.1 0.0 1.4 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KLO07920.1 - 0.0034 16.7 0.0 0.0066 15.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KLO07920.1 - 0.01 15.6 0.1 0.018 14.7 0.1 1.5 1 1 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 KLO07920.1 - 0.022 13.7 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 KLO07920.1 - 0.027 14.3 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF1992 PF09350.10 KLO07921.1 - 1.8e-21 76.0 0.8 3.8e-21 75.0 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) DUF2379 PF09543.10 KLO07921.1 - 1.7 8.9 5.9 19 5.5 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2379) Pro_isomerase PF00160.21 KLO07923.1 - 1.1e-37 129.8 0.0 1.8e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KLO07923.1 - 2.2e-16 59.4 0.0 4e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RloB PF13707.6 KLO07923.1 - 0.017 15.4 0.1 0.028 14.6 0.1 1.2 1 0 0 1 1 1 0 RloB-like protein F-box-like PF12937.7 KLO07924.1 - 0.00067 19.5 0.3 0.0017 18.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO07925.1 - 8.5e-07 28.8 0.1 2.1e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KLO07925.1 - 0.034 14.1 0.2 1.4 9.0 0.1 2.6 2 0 0 2 2 2 0 F-box-like domain p450 PF00067.22 KLO07927.1 - 4.5e-52 177.3 0.0 6.2e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO07928.1 - 5e-62 210.2 0.0 6.2e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO07931.1 - 3.6e-70 237.0 0.0 4.4e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KLO07932.1 - 1.6e-06 27.9 2.2 2.5e-06 27.3 0.5 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO07933.1 - 4e-05 23.4 0.2 4e-05 23.4 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO07934.1 - 3.2e-07 30.1 1.0 3.2e-07 30.1 1.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO07934.1 - 0.023 14.6 2.1 0.17 11.8 2.1 2.5 1 1 0 1 1 1 0 F-box domain BRCT_2 PF16589.5 KLO07934.1 - 0.13 12.7 0.0 0.43 11.0 0.0 1.8 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain F-box-like PF12937.7 KLO07935.1 - 2.3e-06 27.4 1.1 2.3e-06 27.4 1.1 2.5 3 0 0 3 3 3 1 F-box-like YEATS PF03366.16 KLO07936.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 YEATS family PI3K_1B_p101 PF10486.9 KLO07937.1 - 0.5 8.1 5.0 0.64 7.7 5.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Apt1 PF10351.9 KLO07937.1 - 7.7 5.2 11.3 9.5 4.9 11.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Epimerase PF01370.21 KLO07940.1 - 8.2e-09 35.3 0.0 8.7e-08 31.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KLO07940.1 - 1.8e-07 31.2 0.2 3e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KLO07940.1 - 0.0046 16.6 0.1 0.0078 15.8 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KLO07940.1 - 0.0092 16.2 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.24 KLO07940.1 - 0.058 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain BRCT_2 PF16589.5 KLO07941.1 - 0.1 13.0 0.0 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain DUF4170 PF13773.6 KLO07941.1 - 0.11 12.7 0.0 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) p450 PF00067.22 KLO07942.1 - 3.2e-53 181.1 0.0 4e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf_C2HC_14 PF18574.1 KLO07944.1 - 2.4 8.0 6.6 7.1 6.5 0.1 3.5 3 0 0 3 3 3 0 C2HC Zing finger domain DUF4327 PF14217.6 KLO07945.1 - 0.098 12.8 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) Peptidase_C48 PF02902.19 KLO07946.1 - 8.4e-14 51.9 1.1 1.3e-13 51.3 1.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Mst1_SARAH PF11629.8 KLO07948.1 - 0.18 11.9 0.5 1 9.5 0.6 2.1 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Alpha_kinase PF02816.18 KLO07949.1 - 4.5e-06 26.9 0.0 4.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family ADH_zinc_N PF00107.26 KLO07952.1 - 1.3e-19 70.5 0.0 2e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO07952.1 - 4.4e-11 44.0 0.0 8.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO07952.1 - 5.4e-11 42.3 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KLO07952.1 - 0.00034 20.2 0.1 0.00054 19.5 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_2 PF16884.5 KLO07952.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase S10_plectin PF03501.15 KLO07953.1 - 5.1e-39 132.2 0.1 6e-39 132.0 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Cytochrome_P460 PF16694.5 KLO07953.1 - 0.054 13.8 0.0 0.073 13.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P460 F-box-like PF12937.7 KLO07954.1 - 0.18 11.7 0.5 0.4 10.6 0.5 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KLO07954.1 - 0.67 9.9 3.6 0.97 9.4 1.1 2.3 2 0 0 2 2 2 0 F-box domain Nop14 PF04147.12 KLO07954.1 - 5.4 5.1 11.7 8.2 4.5 11.7 1.2 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 KLO07954.1 - 7.2 5.0 5.5 11 4.4 5.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HSP20 PF00011.21 KLO07955.1 - 0.00018 21.6 0.0 0.00082 19.5 0.0 1.8 1 1 0 1 1 1 1 Hsp20/alpha crystallin family IFNGR1 PF07140.11 KLO07956.1 - 0.13 12.4 3.6 0.32 11.1 3.6 1.7 1 1 0 1 1 1 0 Interferon gamma receptor (IFNGR1) Defensin_beta_2 PF13841.6 KLO07956.1 - 0.13 12.8 0.7 0.13 12.8 0.7 3.2 3 1 0 3 3 3 0 Beta defensin AAA PF00004.29 KLO07957.1 - 7.4e-16 58.8 0.0 1.4e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 KLO07957.1 - 1.1e-12 47.9 0.2 2.5e-12 46.7 0.2 1.6 1 0 0 1 1 1 1 BAH domain AAA_lid_10 PF17872.1 KLO07957.1 - 3.6e-09 36.6 0.0 8.9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 KLO07957.1 - 2.9e-08 34.3 0.0 1.3e-07 32.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO07957.1 - 1.3e-06 28.7 0.0 2.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KLO07957.1 - 0.00029 20.2 0.0 0.0016 17.8 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KLO07957.1 - 0.002 18.5 0.0 0.0075 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KLO07957.1 - 0.0023 17.9 0.0 0.01 15.8 0.0 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Apt1 PF10351.9 KLO07957.1 - 0.0027 16.6 0.6 0.0042 16.0 0.6 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain NTPase_1 PF03266.15 KLO07957.1 - 0.043 13.7 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 KLO07957.1 - 0.085 12.8 0.0 0.24 11.3 0.0 1.8 1 1 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 KLO07957.1 - 0.1 12.3 1.6 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KLO07957.1 - 0.15 12.2 2.0 0.19 11.9 0.0 2.3 3 0 0 3 3 2 0 AAA domain Nop14 PF04147.12 KLO07957.1 - 0.16 10.1 10.6 0.25 9.5 10.6 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KLO07957.1 - 0.23 9.7 9.9 0.34 9.2 9.9 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 KLO07957.1 - 0.26 11.4 13.0 0.029 14.5 8.4 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Aminotran_1_2 PF00155.21 KLO07959.1 - 3.9e-27 95.4 0.0 4.8e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KLO07959.1 - 2e-07 30.2 0.0 2.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase PPI_Ypi1 PF07491.11 KLO07960.1 - 8.5e-26 89.6 2.1 8.5e-26 89.6 2.1 2.7 2 1 0 2 2 2 1 Protein phosphatase inhibitor DUF2415 PF10313.9 KLO07961.1 - 2.9e-09 36.7 0.4 6.9e-09 35.5 0.4 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 KLO07961.1 - 0.03 14.6 0.0 0.46 10.8 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KLO07961.1 - 0.077 13.9 11.3 6.2 7.9 0.1 6.1 8 0 0 8 8 8 0 WD domain, G-beta repeat zf-met PF12874.7 KLO07962.1 - 8.9e-08 32.3 13.1 0.079 13.4 0.0 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KLO07962.1 - 1.3e-05 25.4 11.2 0.54 10.6 0.1 4.7 3 1 1 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-RING_5 PF14634.6 KLO07962.1 - 0.00059 19.7 12.2 0.00059 19.7 12.2 3.7 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KLO07962.1 - 0.00076 19.3 13.1 0.00076 19.3 13.1 3.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO07962.1 - 0.00097 19.0 12.5 0.00097 19.0 12.5 3.3 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO07962.1 - 0.0014 19.0 13.0 0.0014 19.0 13.0 2.9 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KLO07962.1 - 0.0023 17.7 10.7 0.0023 17.7 10.7 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 KLO07962.1 - 0.04 14.7 30.6 0.17 12.8 0.9 6.1 6 0 0 6 6 5 0 C2H2-type zinc finger zf-RING_6 PF14835.6 KLO07962.1 - 0.13 12.1 7.4 0.38 10.7 7.4 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.26 KLO07962.1 - 1 10.0 19.9 3.1 8.4 0.0 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KLO07962.1 - 4.3 7.7 15.7 0.058 13.7 4.2 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2207 PF09972.9 KLO07963.1 - 0.12 11.1 0.3 0.13 11.0 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) F-box-like PF12937.7 KLO07964.1 - 0.12 12.3 0.4 0.23 11.4 0.4 1.5 1 0 0 1 1 1 0 F-box-like MPP6 PF10175.9 KLO07966.1 - 0.099 13.1 0.3 0.099 13.1 0.3 1.7 2 0 0 2 2 2 0 M-phase phosphoprotein 6 MATalpha_HMGbox PF04769.12 KLO07966.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box SWIM PF04434.17 KLO07967.1 - 0.00039 20.0 0.1 0.00087 18.9 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger Pirin PF02678.16 KLO07969.1 - 6.5e-30 103.3 0.3 1.4e-29 102.2 0.3 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KLO07969.1 - 3.2e-25 88.5 0.0 1.1e-24 86.7 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KLO07969.1 - 0.011 15.4 0.4 0.18 11.5 0.5 2.4 2 0 0 2 2 2 0 Cupin domain ECH_1 PF00378.20 KLO07970.1 - 2.1e-29 102.6 0.0 2.5e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KLO07970.1 - 6.7e-19 68.6 0.0 7.6e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF2624 PF11116.8 KLO07970.1 - 0.07 14.0 0.1 1.5 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Pheromone PF08015.11 KLO07972.1 - 0.0029 18.6 0.8 0.0054 17.8 0.1 1.9 2 0 0 2 2 2 1 Fungal mating-type pheromone DP PF08781.10 KLO07972.1 - 0.037 13.9 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Transcription factor DP CRM1_C PF08767.11 KLO07973.1 - 4.5e-129 430.2 4.8 6.2e-129 429.8 0.1 3.0 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KLO07973.1 - 5.5e-40 136.9 11.4 5.7e-40 136.8 5.8 3.8 5 0 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KLO07973.1 - 6e-33 112.3 4.2 1.4e-32 111.1 4.2 1.7 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KLO07973.1 - 4.1e-30 103.7 2.9 1.1e-29 102.3 1.4 2.7 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KLO07973.1 - 5.3e-19 67.4 2.9 1.3e-18 66.2 2.9 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KLO07973.1 - 1e-11 44.5 1.9 3.9e-11 42.7 0.5 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KLO07973.1 - 0.0081 16.1 0.6 0.11 12.4 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 KLO07973.1 - 0.67 10.6 4.2 10 6.8 0.0 4.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Pre-PUA PF17832.1 KLO07974.1 - 1.1e-21 77.3 0.3 1.7e-21 76.7 0.3 1.4 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KLO07974.1 - 1.6e-15 56.8 0.0 2.4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KLO07974.1 - 0.0041 17.4 0.0 0.0075 16.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1947) OTU PF02338.19 KLO07975.1 - 9.7e-23 81.0 0.0 1.7e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KLO07975.1 - 1.8e-05 24.3 0.0 0.032 13.7 0.0 2.6 2 1 0 3 3 3 2 Peptidase C65 Otubain T4SS PF07996.11 KLO07975.1 - 0.061 13.7 1.5 0.092 13.1 1.5 1.2 1 0 0 1 1 1 0 Type IV secretion system proteins HAND PF09110.11 KLO07975.1 - 0.32 11.8 8.5 0.44 11.3 8.5 1.2 1 0 0 1 1 1 0 HAND Ndc1_Nup PF09531.10 KLO07975.1 - 0.64 8.6 1.7 0.7 8.5 1.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aldo_ket_red PF00248.21 KLO07976.1 - 3.2e-46 157.9 0.0 3.7e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cpn60_TCP1 PF00118.24 KLO07978.1 - 1.2e-147 492.6 9.4 1.3e-147 492.4 9.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 KLO07978.1 - 0.016 14.7 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 Telomere recombination ATP-synt_Eps PF04627.13 KLO07978.1 - 6.1 6.9 5.4 1.5 8.8 0.2 2.6 3 0 0 3 3 3 0 Mitochondrial ATP synthase epsilon chain COesterase PF00135.28 KLO07979.1 - 2.5e-73 247.7 0.0 4.9e-73 246.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO07979.1 - 1.5e-08 34.8 0.0 5.5e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold TadZ_N PF16968.5 KLO07979.1 - 0.034 13.8 0.2 0.073 12.8 0.2 1.5 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal Abhydrolase_6 PF12697.7 KLO07980.1 - 4.1e-09 37.4 0.5 6.5e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KLO07980.1 - 0.00072 19.3 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KLO07980.1 - 0.013 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KLO07980.1 - 0.086 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 KLO07980.1 - 0.15 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KLO07980.1 - 0.19 11.0 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SRR1 PF07985.12 KLO07981.1 - 2.2e-09 37.2 1.9 1.3e-08 34.7 1.9 2.1 1 1 0 1 1 1 1 SRR1 TPR_1 PF00515.28 KLO07983.1 - 1.2e-22 78.7 11.3 2.1e-05 24.1 0.1 8.0 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KLO07983.1 - 1.7e-20 71.4 18.7 0.0028 17.6 0.2 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO07983.1 - 1.2e-18 67.1 26.9 3.9e-13 49.4 3.3 6.1 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KLO07983.1 - 3.6e-16 59.4 14.6 0.0011 19.5 0.2 7.7 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 KLO07983.1 - 1.7e-12 46.8 0.1 0.12 12.1 0.0 5.8 6 0 0 6 6 6 4 TPR repeat TPR_16 PF13432.6 KLO07983.1 - 3.4e-12 46.8 20.5 0.005 17.5 0.6 6.9 4 1 5 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 KLO07983.1 - 3.7e-11 42.3 8.7 7.7 7.0 0.1 9.0 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 KLO07983.1 - 7.2e-11 42.0 22.4 0.059 14.2 0.2 9.7 6 1 3 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KLO07983.1 - 2.6e-08 34.0 21.8 0.003 17.8 0.7 7.9 5 1 4 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KLO07983.1 - 5.8e-07 29.5 6.4 13 6.4 0.0 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KLO07983.1 - 2.8e-05 24.5 22.0 5.8 7.8 0.1 8.9 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KLO07983.1 - 0.0091 16.0 11.6 0.99 9.6 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat Sel1 PF08238.12 KLO07983.1 - 0.018 15.7 2.4 42 5.0 0.0 4.5 4 0 0 4 4 4 0 Sel1 repeat TBCC_N PF16752.5 KLO07983.1 - 0.07 13.6 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain TPR_15 PF13429.6 KLO07983.1 - 0.072 12.3 19.2 1.4 8.1 5.6 4.0 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KLO07983.1 - 0.14 12.4 13.4 0.43 10.8 0.4 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR_2 PF13041.6 KLO07983.1 - 0.17 12.1 0.0 5.3 7.3 0.0 3.1 3 0 0 3 3 3 0 PPR repeat family PaREP1 PF05942.11 KLO07987.1 - 0.00019 21.4 0.0 0.00078 19.4 0.0 2.0 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family DUF2383 PF09537.10 KLO07987.1 - 0.00019 21.7 8.5 0.063 13.6 0.2 3.3 3 1 0 3 3 3 2 Domain of unknown function (DUF2383) DUF2563 PF10817.8 KLO07987.1 - 0.009 16.6 0.7 0.021 15.4 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2563) Gp-FAR-1 PF05823.12 KLO07987.1 - 0.025 15.0 2.1 4.5 7.6 0.1 3.1 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Cnn_1N PF07989.11 KLO07987.1 - 0.031 14.4 15.8 0.036 14.2 2.0 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 COQ7 PF03232.13 KLO07987.1 - 0.22 11.3 5.7 3.7 7.3 0.1 3.6 4 0 0 4 4 4 0 Ubiquinone biosynthesis protein COQ7 bZIP_1 PF00170.21 KLO07987.1 - 0.28 11.3 10.9 0.67 10.1 0.6 3.2 3 0 0 3 3 3 0 bZIP transcription factor Ax_dynein_light PF10211.9 KLO07987.1 - 0.29 11.1 17.0 0.12 12.3 3.9 2.9 3 0 0 3 3 3 0 Axonemal dynein light chain TSC22 PF01166.18 KLO07987.1 - 0.32 11.3 6.3 6.3 7.2 0.5 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family TolA_bind_tri PF16331.5 KLO07987.1 - 0.6 10.2 9.1 1.7 8.8 1.0 3.3 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF4266 PF14086.6 KLO07987.1 - 0.65 11.0 2.0 4.4 8.3 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) HMMR_C PF15908.5 KLO07987.1 - 0.69 10.2 8.7 3.5 7.9 0.4 2.9 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor C-terminal Shugoshin_N PF07558.11 KLO07987.1 - 0.87 9.5 7.9 0.27 11.1 0.6 2.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region GrpE PF01025.19 KLO07987.1 - 1.2 8.7 13.3 0.92 9.1 1.0 2.7 3 0 0 3 3 3 0 GrpE YabA PF06156.13 KLO07987.1 - 1.6 9.5 13.7 2.5 8.8 0.9 3.3 4 0 0 4 4 4 0 Initiation control protein YabA Fez1 PF06818.15 KLO07987.1 - 2.3 8.7 16.5 29 5.0 16.6 2.5 1 1 0 1 1 1 0 Fez1 Cep57_MT_bd PF06657.13 KLO07987.1 - 2.4 8.7 11.0 3 8.3 0.6 2.9 3 0 0 3 3 2 0 Centrosome microtubule-binding domain of Cep57 TMF_DNA_bd PF12329.8 KLO07987.1 - 4.5 7.3 20.8 8.2 6.5 3.0 4.4 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 KLO07987.1 - 6.1 7.3 8.2 27 5.3 0.5 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 KLO07987.1 - 6.3 6.9 13.6 0.11 12.6 3.2 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Enkurin PF13864.6 KLO07987.1 - 6.3 7.3 16.8 6.2 7.3 2.9 3.7 3 1 0 3 3 3 0 Calmodulin-binding DivIVA PF05103.13 KLO07987.1 - 7 6.8 17.2 1.8 8.7 4.2 2.8 3 0 0 3 3 2 0 DivIVA protein Med21 PF11221.8 KLO07987.1 - 9 6.5 20.0 1.2 9.3 3.1 4.2 3 1 1 4 4 4 0 Subunit 21 of Mediator complex Mog1 PF04603.12 KLO07989.1 - 4.8e-38 130.6 0.2 9.3e-38 129.7 0.2 1.4 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Ndc80_HEC PF03801.13 KLO07990.1 - 7.2e-34 116.6 0.0 1.6e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 KLO07990.1 - 2.1e-07 30.9 2.1 2.1e-07 30.9 2.1 5.2 5 2 2 7 7 7 1 Domain of unknown function (DUF5595) Uds1 PF15456.6 KLO07990.1 - 0.00012 22.3 0.7 0.00012 22.3 0.7 2.8 2 1 1 3 3 3 1 Up-regulated During Septation Bap31_Bap29_C PF18035.1 KLO07990.1 - 0.12 12.4 0.2 0.12 12.4 0.2 3.4 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF724 PF05266.14 KLO07990.1 - 0.19 11.6 17.8 0.097 12.5 2.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KLO07990.1 - 0.6 8.9 35.9 0.29 10.0 9.6 3.3 2 2 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 KLO07990.1 - 0.72 10.4 41.3 0.44 11.1 10.7 4.3 2 2 1 4 4 4 0 Apg6 coiled-coil region Fib_alpha PF08702.10 KLO07990.1 - 0.89 9.7 25.6 1.6 8.9 2.3 4.1 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KLO07990.1 - 1.2 9.1 12.0 4.4 7.3 1.9 3.7 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 KLO07990.1 - 4 7.8 24.6 1.5 9.2 1.8 4.6 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Band_7_1 PF13421.6 KLO07990.1 - 5.4 6.7 5.4 0.82 9.3 1.1 1.7 2 0 0 2 2 2 0 SPFH domain-Band 7 family TSC22 PF01166.18 KLO07990.1 - 7.9 6.9 11.2 1.8 8.9 1.1 4.0 2 2 1 3 3 3 0 TSC-22/dip/bun family DUF1772 PF08592.11 KLO07992.1 - 0.018 15.3 3.6 0.52 10.6 0.2 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) CitMHS PF03600.16 KLO07992.1 - 0.18 11.0 3.1 0.43 9.7 3.2 1.6 1 1 0 1 1 1 0 Citrate transporter SdpI PF13630.6 KLO07992.1 - 2.3 8.4 9.2 0.15 12.2 0.9 2.7 2 1 0 2 2 2 0 SdpI/YhfL protein family F-box-like PF12937.7 KLO07993.1 - 1.2e-06 28.2 0.7 5.5e-06 26.2 0.7 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO07993.1 - 0.23 11.4 3.9 11 6.0 0.4 3.7 4 0 0 4 4 4 0 F-box domain F-box-like PF12937.7 KLO07994.1 - 5.2e-09 35.9 0.5 1.5e-08 34.4 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO07994.1 - 0.085 12.8 5.7 2.4 8.1 0.4 3.5 4 0 0 4 4 4 0 F-box domain Surp PF01805.20 KLO07994.1 - 0.43 10.6 2.3 0.44 10.6 0.4 1.9 2 0 0 2 2 2 0 Surp module F-box-like PF12937.7 KLO07995.1 - 3.8e-06 26.7 1.1 9.2e-06 25.5 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KLO07995.1 - 0.016 15.2 0.1 0.056 13.4 0.0 2.0 2 0 0 2 2 2 0 F-box-like domain F-box-like PF12937.7 KLO07996.1 - 7.8e-08 32.1 0.0 2.7e-07 30.4 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO07996.1 - 0.38 10.7 3.5 24 5.0 0.2 3.6 4 0 0 4 4 4 0 F-box domain LRR_6 PF13516.6 KLO07997.1 - 0.86 9.8 2.7 4.6 7.6 0.2 3.5 5 0 0 5 5 5 0 Leucine Rich repeat F-box-like PF12937.7 KLO07998.1 - 3.3e-07 30.1 0.1 8.9e-07 28.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO07998.1 - 0.073 13.0 0.4 24 4.9 0.0 3.5 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.7 KLO07998.1 - 0.17 12.4 5.1 0.31 11.5 0.2 3.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO07999.1 - 1.6e-08 34.3 0.1 4e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08000.1 - 0.00069 19.5 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO08000.1 - 0.017 15.6 4.6 0.27 11.7 2.4 3.2 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO08001.1 - 5.1e-07 29.5 1.3 1e-06 28.5 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO08001.1 - 0.0054 16.6 3.0 18 5.3 0.0 4.2 4 0 0 4 4 4 3 F-box domain LRR_4 PF12799.7 KLO08001.1 - 5.4 7.6 7.2 96 3.6 0.1 4.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Wbp11 PF09429.10 KLO08003.1 - 9.3e-16 58.0 11.4 1.6e-15 57.2 9.1 2.3 2 0 0 2 2 2 1 WW domain binding protein 11 DUF5082 PF16888.5 KLO08003.1 - 0.028 14.7 2.2 0.21 11.9 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) TMF_TATA_bd PF12325.8 KLO08003.1 - 0.075 13.3 3.5 0.18 12.1 3.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Glyco_transf_8C PF08437.10 KLO08003.1 - 0.16 12.1 1.2 13 6.0 0.1 3.0 3 0 0 3 3 3 0 Glycosyl transferase family 8 C-terminal DUF5127 PF17168.4 KLO08004.1 - 2e-60 204.4 6.6 3.5e-60 203.6 3.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO08004.1 - 1.2e-49 168.3 1.8 2.5e-49 167.3 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO08004.1 - 2.3e-40 138.8 0.2 4.8e-40 137.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO08004.1 - 4.2e-07 29.4 0.3 1e-06 28.2 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KLO08004.1 - 0.022 14.0 0.0 0.13 11.5 0.0 2.1 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain ATG101 PF07855.12 KLO08005.1 - 7.6e-44 149.4 0.2 8.7e-44 149.2 0.2 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Sugar_tr PF00083.24 KLO08006.1 - 2.2e-79 267.5 20.6 2.5e-79 267.3 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO08006.1 - 1.2e-21 77.1 24.0 1.2e-21 77.1 24.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Cpn60_TCP1 PF00118.24 KLO08007.1 - 1.2e-163 545.3 4.1 1.3e-163 545.1 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF627 PF04781.12 KLO08007.1 - 0.014 15.4 0.0 0.047 13.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF627) F-box-like PF12937.7 KLO08008.1 - 1.6e-05 24.7 0.1 4.3e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08010.1 - 0.00012 21.9 0.2 0.00052 19.9 0.1 2.2 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08011.1 - 4.6e-07 29.6 1.1 1.1e-06 28.4 1.1 1.7 1 0 0 1 1 1 1 F-box-like AHD PF17793.1 KLO08011.1 - 0.21 11.4 1.0 0.43 10.4 0.1 1.9 2 0 0 2 2 2 0 ANC1 homology domain (AHD) F-box-like PF12937.7 KLO08012.1 - 3.5e-07 30.0 1.1 1.3e-06 28.2 1.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO08012.1 - 0.024 15.1 1.1 8 7.0 0.7 4.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) EzrA PF06160.12 KLO08012.1 - 0.23 9.6 0.7 0.34 9.0 0.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA F-box-like PF12937.7 KLO08013.1 - 0.00031 20.6 0.6 0.00086 19.1 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO08014.1 - 9.8e-05 22.2 0.1 0.00034 20.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like Pkinase_Tyr PF07714.17 KLO08015.1 - 2e-39 135.5 0.0 3.8e-39 134.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08015.1 - 3.2e-37 128.4 0.0 3.9e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KLO08015.1 - 9.3e-05 22.1 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KLO08015.1 - 0.00021 20.7 0.0 0.00042 19.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Cupin_2 PF07883.11 KLO08016.1 - 8.4e-08 31.8 0.0 1.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain DUF4139 PF13598.6 KLO08016.1 - 0.0016 18.2 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) Cupin_3 PF05899.12 KLO08016.1 - 0.0026 17.4 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) DAP3 PF10236.9 KLO08016.1 - 0.19 10.9 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RseC_MucC PF04246.12 KLO08017.1 - 4.2 7.3 5.2 1.3 9.0 0.6 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Pkinase_Tyr PF07714.17 KLO08018.1 - 8.4e-48 162.9 0.0 1.1e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08018.1 - 8.4e-44 149.9 0.0 1e-43 149.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO08018.1 - 6.7e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO08018.1 - 7.8e-05 22.7 0.0 0.00017 21.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO08018.1 - 0.007 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KLO08018.1 - 0.0079 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cupin_2 PF07883.11 KLO08019.1 - 5.5e-11 42.0 0.0 8.9e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KLO08019.1 - 0.0019 17.9 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KLO08019.1 - 0.058 13.3 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain DAP3 PF10236.9 KLO08019.1 - 0.18 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PMI_typeI PF01238.21 KLO08020.1 - 3.7e-80 269.9 0.0 5.1e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I zf-RING_2 PF13639.6 KLO08021.1 - 8.1e-10 38.9 10.6 8.1e-10 38.9 10.6 4.6 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 KLO08021.1 - 1.3e-07 31.4 8.0 1.3e-07 31.4 8.0 4.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO08021.1 - 3.1e-07 30.3 9.1 3.1e-07 30.3 9.1 4.4 4 1 1 5 5 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KLO08021.1 - 6e-07 29.2 9.5 6e-07 29.2 9.5 3.7 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO08021.1 - 2.6e-06 27.4 5.4 2.6e-06 27.4 5.4 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KLO08021.1 - 6.2e-06 26.0 9.8 6.2e-06 26.0 9.8 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KLO08021.1 - 0.00014 22.1 6.9 0.00014 22.1 6.9 3.9 4 1 0 4 4 4 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KLO08021.1 - 0.00036 20.3 12.5 0.00036 20.3 12.5 4.1 5 1 1 6 6 6 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KLO08021.1 - 0.0069 16.1 5.3 0.0069 16.1 5.3 3.9 4 0 0 4 4 4 1 RING-like zinc finger zf-C2H2 PF00096.26 KLO08021.1 - 0.0075 16.7 32.8 0.15 12.6 0.9 5.9 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KLO08021.1 - 0.015 15.6 0.7 0.015 15.6 0.7 6.2 7 0 0 7 7 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KLO08021.1 - 0.024 15.3 2.7 0.024 15.3 2.7 2.4 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KLO08021.1 - 0.051 14.0 0.2 0.051 14.0 0.2 6.5 7 1 0 7 7 7 0 Zinc-finger of C2H2 type zf-RING_6 PF14835.6 KLO08021.1 - 0.1 12.5 4.2 0.073 12.9 1.3 2.2 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2_6 PF13912.6 KLO08021.1 - 2 8.5 25.7 1 9.5 0.2 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KLO08021.1 - 2.6 9.1 40.5 1 10.4 0.3 6.6 7 0 0 7 7 6 0 C2H2-type zinc finger HypA PF01155.19 KLO08021.1 - 5.6 7.0 22.9 0.15 12.0 1.6 4.7 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_3 PF13920.6 KLO08022.1 - 2.4e-09 36.9 5.4 2.4e-09 36.9 5.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO08022.1 - 3.2e-09 36.5 4.5 3.2e-09 36.5 4.5 2.9 3 1 1 4 4 3 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KLO08022.1 - 8.5e-08 32.4 5.6 8.5e-08 32.4 5.6 3.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KLO08022.1 - 2.8e-07 30.2 5.5 2.8e-07 30.2 5.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO08022.1 - 5.6e-06 26.1 4.3 5.6e-06 26.1 4.3 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO08022.1 - 1.8e-05 24.6 8.6 1.8e-05 24.6 8.6 3.6 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KLO08022.1 - 9.6e-05 22.3 4.1 9.6e-05 22.3 4.1 3.3 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_4 PF14570.6 KLO08022.1 - 0.003 17.3 3.4 0.003 17.3 3.4 2.6 2 1 1 3 3 2 1 RING/Ubox like zinc-binding domain TerY_C PF15616.6 KLO08022.1 - 0.0039 17.3 1.5 0.0071 16.5 1.5 1.4 1 0 0 1 1 1 1 TerY-C metal binding domain zf-rbx1 PF12678.7 KLO08022.1 - 0.0043 17.3 5.0 0.0043 17.3 5.0 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 KLO08022.1 - 0.055 13.4 1.3 0.099 12.6 0.5 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_4 PF13894.6 KLO08022.1 - 0.07 14.0 19.3 1.5 9.8 0.3 5.3 6 0 0 6 6 5 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO08022.1 - 0.25 11.9 11.0 3.5 8.3 0.0 5.0 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KLO08022.1 - 0.73 10.4 8.0 4.6 7.9 0.2 3.7 4 0 0 4 4 3 0 Zinc-finger double domain zf-P11 PF03854.14 KLO08022.1 - 4.5 7.0 10.0 0.79 9.4 3.6 2.8 2 1 0 2 2 2 0 P-11 zinc finger zf-C3HC4_3 PF13920.6 KLO08023.1 - 8.5e-11 41.6 8.2 8.5e-11 41.6 8.2 3.9 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO08023.1 - 2.7e-09 37.2 10.0 2.7e-09 37.2 10.0 3.9 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 KLO08023.1 - 3.5e-09 36.4 10.1 3.5e-09 36.4 10.1 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO08023.1 - 5.7e-08 32.6 4.4 5.7e-08 32.6 4.4 3.6 3 2 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KLO08023.1 - 9.1e-08 31.8 9.5 9.1e-08 31.8 9.5 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO08023.1 - 1.5e-06 28.0 8.3 1.5e-06 28.0 8.3 3.8 3 1 1 4 4 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KLO08023.1 - 2.1e-06 27.6 8.9 2.1e-06 27.6 8.9 4.4 3 3 1 4 4 4 1 zinc-RING finger domain zf-C2H2 PF00096.26 KLO08023.1 - 5.6e-06 26.5 0.7 0.0023 18.3 0.0 5.9 6 0 0 6 6 5 2 Zinc finger, C2H2 type zf-C3HC4_4 PF15227.6 KLO08023.1 - 1.8e-05 24.8 6.5 1.8e-05 24.8 6.5 3.9 5 1 0 5 5 4 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KLO08023.1 - 0.00022 21.5 6.3 0.00022 21.5 6.3 3.2 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-C2H2_4 PF13894.6 KLO08023.1 - 0.00082 20.0 31.4 0.26 12.2 0.0 6.3 6 1 0 6 6 5 3 C2H2-type zinc finger zf-RING_4 PF14570.6 KLO08023.1 - 0.0018 18.0 6.9 0.0018 18.0 6.9 4.1 5 1 0 5 5 5 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 KLO08023.1 - 0.002 17.5 1.0 0.028 13.8 0.1 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C2H2_6 PF13912.6 KLO08023.1 - 0.032 14.2 0.3 0.032 14.2 0.3 5.8 6 0 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.7 KLO08023.1 - 0.044 14.2 1.3 0.044 14.2 1.3 6.1 8 1 1 9 9 7 0 Zinc-finger of C2H2 type zf-P11 PF03854.14 KLO08023.1 - 0.062 13.0 10.8 0.057 13.1 2.9 3.4 3 0 0 3 3 3 0 P-11 zinc finger zf-CHY PF05495.12 KLO08023.1 - 0.42 11.1 21.9 0.46 11.0 2.8 3.3 3 0 0 3 3 3 0 CHY zinc finger zf-RING_11 PF17123.5 KLO08023.1 - 5.4 6.9 20.8 0.45 10.3 6.6 3.6 3 1 0 3 3 3 0 RING-like zinc finger zf-MYST PF17772.1 KLO08023.1 - 7 6.3 9.9 0.47 10.1 1.0 3.3 4 0 0 4 4 4 0 MYST family zinc finger domain zf-C3HC4_3 PF13920.6 KLO08024.1 - 3.9e-08 33.0 4.4 3.9e-08 33.0 4.4 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO08024.1 - 6.6e-06 25.9 5.9 6.6e-06 25.9 5.9 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KLO08024.1 - 2.5e-05 24.0 6.2 2.5e-05 24.0 6.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO08024.1 - 3.2e-05 23.7 5.4 3.2e-05 23.7 5.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO08024.1 - 0.002 18.4 7.6 0.002 18.4 7.6 2.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KLO08024.1 - 0.0022 17.9 5.4 0.0022 17.9 5.4 2.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-C2H2 PF00096.26 KLO08024.1 - 0.0094 16.4 0.2 0.16 12.5 0.0 4.2 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO08024.1 - 0.046 14.6 14.1 0.28 12.1 0.1 4.2 5 0 0 5 5 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KLO08024.1 - 0.055 13.2 0.2 0.055 13.2 0.2 2.6 3 0 0 3 3 2 0 zinc-finger C2H2-type zf-P11 PF03854.14 KLO08024.1 - 0.06 13.0 1.4 0.06 13.0 1.4 2.6 3 0 0 3 3 3 0 P-11 zinc finger zf-LYAR PF08790.11 KLO08024.1 - 0.16 11.9 3.1 0.93 9.4 0.0 2.6 3 0 0 3 3 2 0 LYAR-type C2HC zinc finger zf-RING_UBOX PF13445.6 KLO08024.1 - 0.33 11.0 11.1 0.087 12.9 2.4 2.9 3 0 0 3 3 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 KLO08024.1 - 0.94 9.8 7.5 0.33 11.3 3.8 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf_UBZ PF18439.1 KLO08024.1 - 2 8.1 8.4 23 4.7 0.0 4.0 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger Lar_restr_allev PF14354.6 KLO08024.1 - 2.9 8.3 0.0 2.9 8.3 0.0 3.1 3 1 1 4 4 4 0 Restriction alleviation protein Lar zf-C3HC4_4 PF15227.6 KLO08024.1 - 3.4 7.9 12.0 9.4 6.5 8.4 3.3 2 1 2 4 4 4 0 zinc finger of C3HC4-type, RING Zn-ribbon_8 PF09723.10 KLO08024.1 - 3.9 7.7 14.4 1.3 9.2 0.1 3.9 3 2 0 3 3 3 0 Zinc ribbon domain DZR PF12773.7 KLO08024.1 - 5.9 7.0 9.6 2e+02 2.1 0.0 3.2 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 KLO08024.1 - 8.6 6.2 13.3 0.17 11.7 5.5 2.3 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KLO08025.1 - 0.0015 18.3 13.5 0.009 15.8 14.1 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO08025.1 - 0.0079 16.0 13.0 0.013 15.4 13.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO08025.1 - 0.0091 16.3 12.3 0.014 15.8 12.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KLO08025.1 - 0.013 15.3 11.8 0.02 14.7 11.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO08025.1 - 0.03 14.4 8.9 0.092 12.8 8.9 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KLO08025.1 - 0.28 11.2 13.3 0.45 10.5 13.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KLO08025.1 - 3.3 7.6 12.1 1.8e+02 2.1 13.0 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Form_Nir_trans PF01226.17 KLO08026.1 - 2.5e-59 200.5 18.9 3e-59 200.2 18.9 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Methyltransf_10 PF05971.12 KLO08027.1 - 3.5e-73 246.6 0.0 4.5e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase PrmA PF06325.13 KLO08027.1 - 0.004 16.6 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KLO08027.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Pkinase PF00069.25 KLO08028.1 - 3.7e-05 23.2 0.0 4.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KLO08028.1 - 0.033 13.0 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF4502 PF14950.6 KLO08030.1 - 2.8e-06 27.0 0.1 4.7e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) eIF2_C PF09173.11 KLO08031.1 - 3.1e-31 107.5 0.4 7.6e-31 106.2 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KLO08031.1 - 5.7e-21 74.9 3.1 5.4e-20 71.8 3.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KLO08031.1 - 3.5e-09 36.9 0.5 9.9e-09 35.5 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KLO08031.1 - 0.0014 18.6 1.0 0.015 15.2 0.3 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KLO08031.1 - 0.0068 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KLO08031.1 - 0.0084 16.1 3.4 0.011 15.8 0.2 2.6 3 0 0 3 3 3 1 C-terminal region of MMR_HSR1 domain F-box-like PF12937.7 KLO08032.1 - 3e-05 23.8 0.0 9.5e-05 22.2 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO08032.1 - 0.16 12.4 1.1 5.8 7.5 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) EF-hand_13 PF17958.1 KLO08032.1 - 0.19 11.6 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain DUF5645 PF18713.1 KLO08033.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5645) F-box-like PF12937.7 KLO08034.1 - 5e-05 23.1 0.3 0.00017 21.4 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO08035.1 - 1.8e-07 30.9 2.2 5e-07 29.5 2.2 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO08035.1 - 0.03 14.2 0.8 3 7.8 0.1 2.5 2 0 0 2 2 2 0 F-box domain alpha-hel2 PF14456.6 KLO08035.1 - 0.8 9.0 2.2 0.87 8.8 0.6 1.7 1 1 1 2 2 2 0 Alpha-helical domain 2 Ribonuc_2-5A PF06479.12 KLO08036.1 - 0.033 14.4 0.6 0.071 13.3 0.1 1.7 1 1 0 1 1 1 0 Ribonuclease 2-5A AAA_23 PF13476.6 KLO08036.1 - 0.043 14.3 9.0 0.048 14.2 9.0 1.1 1 0 0 1 1 1 0 AAA domain LPD5 PF18799.1 KLO08036.1 - 0.18 12.2 6.1 0.23 11.8 5.5 1.5 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 5 NEMP PF10225.9 KLO08036.1 - 0.23 11.1 0.4 0.33 10.6 0.4 1.2 1 0 0 1 1 1 0 NEMP family DUF1221 PF06760.11 KLO08036.1 - 0.76 9.2 8.8 1.7 8.1 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1221) NIPSNAP PF07978.13 KLO08037.1 - 0.017 15.3 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 NIPSNAP Lipase_3 PF01764.25 KLO08038.1 - 2e-32 112.0 0.0 3.2e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.22 KLO08038.1 - 0.015 15.2 0.3 0.064 13.2 0.2 2.0 2 1 0 2 2 2 0 Cutinase Abhydrolase_6 PF12697.7 KLO08038.1 - 0.068 13.8 1.1 0.12 13.0 0.7 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family HTH_12 PF08461.10 KLO08040.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain GPR15L PF15854.5 KLO08042.1 - 0.06 13.6 0.3 0.083 13.1 0.3 1.3 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 OPT PF03169.15 KLO08043.1 - 2.6e-174 581.3 56.9 8.5e-174 579.6 56.9 1.7 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Herpes_pp38 PF04846.13 KLO08043.1 - 0.2 11.6 0.9 0.83 9.6 0.9 2.1 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein DUF3290 PF11694.8 KLO08043.1 - 0.37 10.8 2.1 7 6.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) DUF2981 PF11200.8 KLO08044.1 - 0.073 12.8 1.2 0.094 12.4 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF2070 PF09843.9 KLO08044.1 - 5.1 5.3 8.4 6.1 5.0 8.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Tmemb_170 PF10190.9 KLO08045.1 - 9.3e-08 32.4 7.2 6.4e-06 26.5 2.7 2.1 2 0 0 2 2 2 2 Putative transmembrane protein 170 DUF3040 PF11239.8 KLO08045.1 - 0.12 12.7 0.8 0.16 12.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) FtsX PF02687.21 KLO08045.1 - 0.75 10.3 6.5 1.2 9.6 4.0 2.0 2 0 0 2 2 2 0 FtsX-like permease family SAICAR_synt PF01259.18 KLO08046.1 - 1.2e-92 310.1 0.0 1.6e-92 309.7 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Fis1_TPR_C PF14853.6 KLO08047.1 - 7.6e-18 64.3 0.4 1.3e-17 63.5 0.4 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KLO08047.1 - 7.6e-14 51.1 0.1 1.3e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KLO08047.1 - 1.9e-05 24.4 0.0 0.00011 22.0 0.0 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO08047.1 - 6.6e-05 23.1 0.1 0.00011 22.3 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KLO08047.1 - 0.0043 17.5 0.0 0.0099 16.4 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KLO08047.1 - 0.0052 17.3 0.5 0.043 14.5 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KLO08047.1 - 0.018 14.9 0.4 0.059 13.2 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KLO08047.1 - 0.053 13.8 0.1 1.3 9.4 0.0 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat Gram_pos_anchor PF00746.21 KLO08047.1 - 2.5 8.1 4.1 4.9 7.2 4.1 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif zf-H2C2_2 PF13465.6 KLO08048.1 - 2.8e-23 81.2 34.3 2.2e-06 27.8 1.4 6.8 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KLO08048.1 - 1e-20 72.9 51.4 2.5e-05 24.5 1.6 8.5 9 0 0 9 9 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO08048.1 - 3.3e-14 52.4 56.0 0.00019 22.0 1.9 9.1 9 0 0 9 9 7 6 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KLO08048.1 - 3e-07 30.7 15.1 0.02 15.2 0.7 4.9 2 1 2 5 5 5 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 KLO08048.1 - 3.4e-05 24.4 40.7 0.66 10.6 1.0 7.4 5 2 3 8 8 8 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KLO08048.1 - 0.00019 21.6 22.1 0.015 15.6 0.5 5.9 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 KLO08048.1 - 0.00041 20.4 14.3 0.019 15.0 0.5 4.9 5 0 0 5 5 5 2 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 KLO08048.1 - 0.0016 18.3 21.0 0.47 10.5 1.5 6.0 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KLO08048.1 - 0.003 17.3 24.3 0.0052 16.5 3.1 5.4 5 1 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2HE PF16278.5 KLO08048.1 - 0.0053 17.2 8.3 12 6.4 0.8 4.0 3 0 0 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 KLO08048.1 - 0.03 14.2 9.2 6.5 6.8 0.5 5.2 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KLO08048.1 - 0.32 10.8 21.1 1.7 8.5 0.4 6.2 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KLO08048.1 - 1.3 9.4 23.7 0.085 13.2 5.6 4.4 3 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KLO08048.1 - 5.3 6.7 10.2 2 8.1 0.3 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Tma16 PF11176.8 KLO08049.1 - 5.8e-45 152.8 2.7 6.9e-45 152.5 2.7 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Pkinase PF00069.25 KLO08050.1 - 2.7e-66 223.6 0.0 4.5e-66 222.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08050.1 - 1e-33 116.7 0.0 1.7e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 KLO08050.1 - 1.4e-05 24.8 0.0 0.00011 21.9 0.0 2.2 1 1 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 KLO08050.1 - 0.0061 15.9 0.0 0.1 11.9 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KLO08050.1 - 0.007 16.3 0.0 0.057 13.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DNA_ligase_A_M PF01068.21 KLO08051.1 - 5.2e-53 179.7 0.0 1.2e-52 178.6 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KLO08051.1 - 2.1e-41 142.2 1.5 2.4e-41 142.0 0.1 1.9 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 KLO08051.1 - 6.8e-26 90.5 0.3 1e-11 45.0 0.0 3.2 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KLO08051.1 - 7e-15 55.4 0.1 4.9e-14 52.7 0.0 2.6 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KLO08051.1 - 1e-11 45.5 0.1 2.2e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 KLO08051.1 - 9.3e-10 38.8 0.1 3.8e-05 24.0 0.0 3.1 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KLO08051.1 - 0.0017 18.6 1.5 0.067 13.5 0.0 3.5 3 1 0 3 3 3 1 DNA ligase 3 BRCT domain Spore_YhcN_YlaJ PF09580.10 KLO08051.1 - 0.021 14.9 0.7 0.19 11.8 0.2 2.3 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) PTCB-BRCT PF12738.7 KLO08051.1 - 0.037 14.0 0.0 10 6.1 0.0 3.3 3 0 0 3 3 3 0 twin BRCT domain mRNA_cap_enzyme PF01331.19 KLO08051.1 - 0.074 12.9 2.2 1.2 9.0 0.2 3.4 3 1 0 3 3 3 0 mRNA capping enzyme, catalytic domain RTT107_BRCT_5 PF16770.5 KLO08051.1 - 0.11 12.3 0.5 14 5.6 0.0 3.0 3 0 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain Adaptin_N PF01602.20 KLO08052.1 - 1.5e-146 489.0 8.3 1.8e-146 488.8 8.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KLO08052.1 - 2.8e-23 82.3 1.0 6.6e-23 81.1 1.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KLO08052.1 - 1.1e-05 25.5 9.4 0.00056 20.0 0.5 3.7 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KLO08052.1 - 0.00048 20.5 5.2 1.9 9.0 0.1 4.4 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KLO08052.1 - 0.013 15.7 1.9 58 4.3 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat FAA_hydrolase_N PF09298.11 KLO08052.1 - 0.038 14.2 0.2 0.57 10.4 0.1 2.8 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal Peptidase_M73 PF12389.8 KLO08052.1 - 0.057 13.3 0.2 0.097 12.5 0.2 1.3 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase TIP120 PF08623.10 KLO08052.1 - 2.6 7.8 5.7 7 6.4 0.2 3.6 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) AIP3 PF03915.13 KLO08053.1 - 8.8e-142 473.0 8.9 1.7e-141 472.0 8.9 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 OmpH PF03938.14 KLO08053.1 - 0.22 11.9 15.5 0.66 10.3 0.2 4.0 4 1 1 5 5 5 0 Outer membrane protein (OmpH-like) Phage_Mu_Gam PF07352.12 KLO08053.1 - 0.29 11.1 6.9 5.6 6.8 0.6 3.0 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Lectin_N PF03954.14 KLO08053.1 - 1.2 8.9 6.6 0.18 11.5 1.1 2.6 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF948 PF06103.11 KLO08053.1 - 1.4 9.2 6.4 44 4.4 6.1 3.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KLO08053.1 - 2.6 8.1 7.9 5.8 7.0 2.3 3.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KLO08053.1 - 4.9 7.2 12.3 23 5.0 1.1 4.7 4 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 KLO08053.1 - 8.1 6.9 9.4 8.3 6.9 0.8 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) PALP PF00291.25 KLO08054.1 - 1.1e-53 182.5 0.3 1.6e-53 182.1 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sugar_tr PF00083.24 KLO08055.1 - 6e-76 256.1 21.4 6.9e-76 255.9 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO08055.1 - 2.2e-23 82.7 33.1 2.2e-23 82.7 33.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RabGAP-TBC PF00566.18 KLO08055.1 - 0.15 11.7 0.5 0.26 10.9 0.5 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain DUF5345 PF17280.2 KLO08055.1 - 0.28 11.2 6.0 0.31 11.0 0.9 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5345) DUF554 PF04474.12 KLO08055.1 - 1.1 8.7 9.8 0.26 10.7 3.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF554) DOPA_dioxygen PF08883.11 KLO08056.1 - 7.1e-46 154.8 0.2 9e-46 154.5 0.2 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family E1_DerP2_DerF2 PF02221.15 KLO08057.1 - 1.5e-23 83.7 0.6 2e-23 83.3 0.6 1.1 1 0 0 1 1 1 1 ML domain Myco_arth_vir_N PF09610.10 KLO08057.1 - 1.8 8.7 3.8 3.5 7.8 3.8 1.5 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Bunya_G2 PF03563.13 KLO08059.1 - 1.1 8.5 4.5 1.3 8.2 4.5 1.0 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Sds3 PF08598.11 KLO08060.1 - 6.9e-08 32.8 0.0 1.3e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 Sds3-like Forkhead PF00250.18 KLO08061.1 - 7.7e-18 64.5 0.1 9.6e-18 64.2 0.1 1.0 1 0 0 1 1 1 1 Forkhead domain SF3b1 PF08920.10 KLO08062.1 - 1.3e-21 77.3 3.0 1.3e-21 77.3 3.0 2.1 2 0 0 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 KLO08062.1 - 1.7e-09 38.0 6.1 0.0031 18.0 0.0 7.8 8 1 1 9 9 9 1 HEAT-like repeat HEAT_2 PF13646.6 KLO08062.1 - 1.7e-08 34.8 16.6 0.0016 18.8 0.2 8.1 5 2 3 9 9 9 4 HEAT repeats HEAT PF02985.22 KLO08062.1 - 1.2e-07 31.3 13.1 0.53 10.7 0.0 9.7 13 0 0 13 13 11 1 HEAT repeat Adaptin_N PF01602.20 KLO08062.1 - 7.4e-07 28.1 1.9 0.0071 15.0 0.0 3.3 2 1 0 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KLO08062.1 - 4.2e-05 24.1 3.9 1.3 9.7 0.0 5.5 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KLO08062.1 - 0.00016 21.8 11.4 0.14 12.2 0.0 6.7 7 2 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KLO08062.1 - 0.0023 17.5 0.8 0.46 10.0 0.1 3.1 2 1 0 2 2 2 1 CLASP N terminal UME PF08064.13 KLO08062.1 - 0.0034 17.3 0.0 1.6 8.7 0.0 4.6 4 1 1 5 5 5 1 UME (NUC010) domain NUC173 PF08161.12 KLO08062.1 - 0.0051 16.5 0.3 2.5 7.7 0.0 4.5 5 1 1 6 6 6 1 NUC173 domain MMS19_C PF12460.8 KLO08062.1 - 0.016 14.3 0.0 18 4.3 0.0 4.1 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal DUF3110 PF11360.8 KLO08062.1 - 0.022 15.0 0.1 0.077 13.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) DUF3385 PF11865.8 KLO08062.1 - 0.05 13.5 2.7 7.8 6.4 0.1 4.3 5 2 0 5 5 5 0 Domain of unknown function (DUF3385) F-box-like PF12937.7 KLO08063.1 - 1.6e-07 31.1 0.1 4.9e-07 29.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08065.1 - 2.3e-06 27.4 0.1 6.6e-06 25.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 KLO08066.1 - 5.4e-33 112.5 21.8 1.4e-06 28.9 0.1 7.2 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO08066.1 - 2.2e-14 53.5 0.0 0.003 17.8 0.1 5.6 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO08066.1 - 0.00012 22.0 0.2 0.099 12.5 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KLO08066.1 - 0.01 14.9 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Ge1_WD40 PF16529.5 KLO08066.1 - 0.013 14.5 0.1 0.55 9.1 0.1 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KLO08066.1 - 0.094 11.4 0.0 4.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like IKI3 PF04762.12 KLO08066.1 - 0.16 10.0 0.0 0.28 9.1 0.0 1.4 1 0 0 1 1 1 0 IKI3 family Ribonuc_P_40 PF08584.11 KLO08067.1 - 0.023 14.0 0.4 2.4 7.4 0.0 2.2 1 1 1 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit DUF2682 PF10909.8 KLO08067.1 - 0.097 13.2 0.0 0.33 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) TMF_TATA_bd PF12325.8 KLO08067.1 - 0.18 12.0 1.1 0.51 10.6 0.3 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Methyltransf_23 PF13489.6 KLO08068.1 - 1e-16 61.2 0.0 1.2e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO08068.1 - 8.7e-16 58.5 0.0 1.4e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO08068.1 - 1.1e-15 57.7 0.0 1.4e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO08068.1 - 2.4e-15 57.0 0.0 6.2e-15 55.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO08068.1 - 4.9e-15 56.0 0.0 9.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO08068.1 - 2.1e-05 24.0 0.0 4.2e-05 23.0 0.0 1.5 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 KLO08068.1 - 0.00012 21.3 0.0 0.00034 19.8 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 KLO08068.1 - 0.00036 20.1 0.0 0.00051 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KLO08068.1 - 0.0042 16.7 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 KLO08068.1 - 0.021 14.2 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KLO08068.1 - 0.26 10.3 0.0 0.43 9.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase IBR PF01485.21 KLO08069.1 - 2e-11 43.9 36.1 4.5e-09 36.4 11.8 4.4 3 2 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KLO08069.1 - 0.00013 21.8 4.4 0.00013 21.8 4.4 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO08069.1 - 0.002 17.9 1.8 0.002 17.9 1.8 4.9 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO08069.1 - 0.0025 17.7 4.9 0.0025 17.7 4.9 3.4 3 0 0 3 3 3 1 zinc-RING finger domain DUF5113 PF17140.4 KLO08069.1 - 0.014 15.2 1.6 0.027 14.3 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) zf-RING_4 PF14570.6 KLO08069.1 - 1.7 8.5 21.5 2.5 7.9 8.5 3.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KLO08069.1 - 5.3 7.5 33.5 0.047 14.0 5.3 3.7 3 1 1 4 4 4 0 Ring finger domain zf-RING_UBOX PF13445.6 KLO08069.1 - 8.5 6.5 22.6 0.027 14.5 4.1 3.7 3 0 0 3 3 3 0 RING-type zinc-finger RRM_1 PF00076.22 KLO08070.1 - 2.6e-34 116.9 0.0 3.6e-18 65.1 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KLO08070.1 - 0.0095 15.5 0.0 2.1 8.0 0.1 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KLO08070.1 - 0.051 13.7 0.0 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif OB_RNB PF08206.11 KLO08070.1 - 0.12 12.0 0.3 1.6 8.5 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain COX17 PF05051.13 KLO08071.1 - 5.8e-23 81.0 4.7 7.4e-23 80.6 4.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Ofd1_CTDD PF10637.9 KLO08072.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.0 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term WBS28 PF15164.6 KLO08073.1 - 0.031 13.6 0.5 0.039 13.2 0.5 1.2 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue YTV PF07639.11 KLO08074.1 - 0.15 12.2 1.1 0.23 11.6 1.1 1.2 1 0 0 1 1 1 0 YTV SPX PF03105.19 KLO08074.1 - 0.45 10.4 8.4 0.5 10.2 8.4 1.1 1 0 0 1 1 1 0 SPX domain CytochromB561_N PF09786.9 KLO08074.1 - 0.96 8.4 24.9 1.1 8.1 24.9 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Apt1 PF10351.9 KLO08074.1 - 4.3 6.1 14.4 5.4 5.7 14.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KLO08074.1 - 4.5 5.7 13.1 4.9 5.6 13.1 1.1 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 KLO08075.1 - 2.4e-43 145.3 17.5 1.8e-08 34.9 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO08075.1 - 1.7e-19 69.9 0.0 0.0028 17.9 0.0 6.4 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO08075.1 - 2.6e-07 30.7 0.0 0.0058 16.5 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KLO08075.1 - 3.7e-07 29.4 0.2 0.44 9.5 0.0 4.3 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 KLO08075.1 - 0.0002 20.6 0.0 0.00029 20.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Nucleoporin_N PF08801.11 KLO08075.1 - 0.003 16.4 0.0 0.64 8.7 0.0 3.0 2 2 1 3 3 3 2 Nup133 N terminal like Det1 PF09737.9 KLO08075.1 - 0.25 10.4 0.0 0.38 9.8 0.0 1.1 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 KIND PF16474.5 KLO08076.1 - 1.4 8.8 8.1 2 8.3 8.1 1.2 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain F-box-like PF12937.7 KLO08077.1 - 0.00036 20.4 0.0 0.0014 18.5 0.0 2.1 1 0 0 1 1 1 1 F-box-like DUF86 PF01934.17 KLO08078.1 - 0.039 13.8 0.1 0.11 12.4 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF86 zf-ribbon_3 PF13248.6 KLO08078.1 - 0.045 13.2 2.0 0.097 12.1 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Vpu PF00558.19 KLO08078.1 - 0.16 11.7 0.1 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 Vpu protein Efg1 PF10153.9 KLO08078.1 - 0.19 12.1 0.5 79 3.7 0.0 3.1 3 0 0 3 3 3 0 rRNA-processing protein Efg1 DUF5344 PF17279.2 KLO08079.1 - 0.0012 19.4 3.7 0.0083 16.7 2.0 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5344) Dynactin_p22 PF07426.11 KLO08079.1 - 0.0082 16.0 1.5 0.015 15.2 1.5 1.4 1 0 0 1 1 1 1 Dynactin subunit p22 DUF2682 PF10909.8 KLO08079.1 - 0.074 13.6 0.4 0.66 10.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2682) DUF5063 PF16702.5 KLO08079.1 - 0.076 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) MCD_N PF17408.2 KLO08079.1 - 0.086 13.0 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain GAT PF03127.14 KLO08079.1 - 0.091 13.1 0.3 0.2 12.0 0.3 1.4 1 0 0 1 1 1 0 GAT domain Ferritin PF00210.24 KLO08079.1 - 0.14 12.1 0.2 0.25 11.3 0.2 1.3 1 0 0 1 1 1 0 Ferritin-like domain Sec34 PF04136.15 KLO08079.1 - 0.22 11.4 1.7 0.86 9.5 1.3 2.1 1 1 1 2 2 2 0 Sec34-like family zf-ribbon_3 PF13248.6 KLO08079.1 - 0.41 10.1 5.0 0.91 9.0 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbon domain BIR PF00653.21 KLO08080.1 - 0.0015 19.1 1.1 0.0026 18.4 1.1 1.5 1 1 0 1 1 1 1 Inhibitor of Apoptosis domain DZR PF12773.7 KLO08080.1 - 0.0044 17.0 0.5 0.0068 16.4 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon RPA_interact_C PF14768.6 KLO08080.1 - 0.019 15.6 0.2 0.022 15.3 0.2 1.2 1 0 0 1 1 1 0 Replication protein A interacting C-terminal C1_1 PF00130.22 KLO08080.1 - 0.042 13.7 1.3 0.055 13.4 0.7 1.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.6 KLO08080.1 - 0.056 13.2 0.1 0.056 13.2 0.1 1.7 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 KLO08080.1 - 0.12 12.0 0.2 0.12 12.0 0.2 2.0 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 KLO08080.1 - 0.12 11.8 4.0 0.21 11.0 0.2 2.2 1 1 1 2 2 2 0 zinc-ribbon domain zf-FPG_IleRS PF06827.14 KLO08080.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.2 3 1 0 3 3 3 0 Zinc finger found in FPG and IleRS BDV_P40 PF06407.11 KLO08081.1 - 0.086 11.9 0.0 0.22 10.6 0.0 1.7 1 1 1 2 2 2 0 Borna disease virus P40 protein RasGEF PF00617.19 KLO08083.1 - 1.3e-44 152.5 0.0 2e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KLO08083.1 - 1.7e-19 70.0 0.0 3.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF896 PF05979.12 KLO08083.1 - 0.089 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) LRR_4 PF12799.7 KLO08086.1 - 0.93 10.0 6.0 34 5.1 0.1 5.0 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO08087.1 - 0.0006 19.7 0.1 0.0013 18.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF587 PF04532.12 KLO08087.1 - 0.0053 16.1 0.2 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF587) F-box-like PF12937.7 KLO08088.1 - 9e-06 25.5 0.0 7.9e-05 22.5 0.0 2.6 1 1 0 1 1 1 1 F-box-like BRK PF07533.16 KLO08088.1 - 0.0017 17.9 0.1 0.004 16.7 0.1 1.6 1 0 0 1 1 1 1 BRK domain F-box-like PF12937.7 KLO08089.1 - 7.3e-07 29.0 0.0 2.1e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO08089.1 - 0.038 14.4 1.3 6.9 7.2 0.1 4.0 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) DUF587 PF04532.12 KLO08089.1 - 0.064 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF587) PDCD7 PF16021.5 KLO08089.1 - 0.1 11.7 1.3 0.18 10.9 1.3 1.4 1 0 0 1 1 1 0 Programmed cell death protein 7 DUF4802 PF16060.5 KLO08092.1 - 0.25 11.5 1.4 0.4 10.9 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4802) F-box-like PF12937.7 KLO08093.1 - 4.1e-07 29.8 0.0 1.3e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO08093.1 - 0.00025 20.8 0.0 0.00098 18.9 0.0 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO08097.1 - 9.6e-12 44.6 0.1 1.1e-10 41.2 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO08097.1 - 7.8e-05 22.4 0.0 0.00031 20.5 0.0 2.2 1 0 0 1 1 1 1 F-box domain DUF4657 PF15552.6 KLO08099.1 - 0.046 13.3 0.1 0.053 13.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) Mu-like_gpT PF10124.9 KLO08100.1 - 0.1 11.9 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Mu-like prophage major head subunit gpT Pertussis_S2S3 PF02918.15 KLO08103.1 - 0.056 13.4 0.4 0.14 12.0 0.3 1.8 1 1 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain FBPase_glpX PF03320.13 KLO08103.1 - 0.18 10.6 0.1 0.28 10.0 0.1 1.3 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded HMG_box PF00505.19 KLO08106.1 - 7e-10 39.2 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box gag_pre-integrs PF13976.6 KLO08110.1 - 7.9e-10 38.5 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 KLO08111.1 - 1.8e-14 53.6 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HET PF06985.11 KLO08112.1 - 6.2e-07 29.9 0.7 0.00015 22.2 0.0 2.4 1 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Pkinase_fungal PF17667.1 KLO08113.1 - 1.1e-45 156.2 0.0 1.6e-44 152.3 0.0 2.1 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO08113.1 - 0.002 17.6 0.0 0.0065 15.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KLO08113.1 - 0.004 17.1 0.2 0.0083 16.1 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_S7 PF00177.21 KLO08113.1 - 0.011 15.4 0.5 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e Pkinase_fungal PF17667.1 KLO08114.1 - 2.2e-46 158.5 0.0 2.7e-44 151.6 0.0 2.2 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO08114.1 - 0.0024 17.3 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO08114.1 - 0.018 15.0 0.1 0.047 13.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO08115.1 - 4.1e-07 29.1 0.0 6.3e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase HipN PF18253.1 KLO08115.1 - 0.031 14.0 0.1 0.062 13.0 0.1 1.4 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain Pkinase_fungal PF17667.1 KLO08116.1 - 2.3e-42 145.2 0.0 2.1e-21 76.2 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KLO08116.1 - 0.00035 20.0 0.0 0.00076 18.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO08116.1 - 0.0085 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KLO08116.1 - 0.047 13.0 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase bZIP_1 PF00170.21 KLO08119.1 - 0.00018 21.5 5.7 0.00032 20.7 5.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KLO08119.1 - 0.0013 18.8 10.0 0.0024 17.9 10.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KLO08119.1 - 0.062 13.8 3.2 0.14 12.7 3.2 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor GDA1_CD39 PF01150.17 KLO08121.1 - 1.1e-94 317.6 0.0 1.4e-94 317.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Pyr_redox_2 PF07992.14 KLO08122.1 - 1.8e-50 171.9 0.1 2.1e-50 171.6 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO08122.1 - 1.5e-17 63.9 0.1 2.9e-14 53.4 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO08122.1 - 1.5e-16 60.6 0.1 1e-12 47.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO08122.1 - 6.3e-06 25.6 0.1 3.9e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KLO08122.1 - 1.8e-05 24.0 1.6 0.0027 16.9 0.1 2.5 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 KLO08122.1 - 4.2e-05 22.8 4.5 0.0058 15.7 0.1 3.9 4 1 1 5 5 5 1 Glucose inhibited division protein A DAO PF01266.24 KLO08122.1 - 5.2e-05 23.0 0.3 0.15 11.6 0.3 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO08122.1 - 0.00022 21.4 0.4 0.022 15.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KLO08122.1 - 0.00026 20.4 0.0 0.0042 16.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KLO08122.1 - 0.0025 17.1 0.0 0.034 13.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KLO08122.1 - 0.0032 17.9 0.0 0.28 11.6 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 KLO08122.1 - 0.0035 16.2 0.4 0.064 12.1 0.3 2.5 2 1 1 3 3 3 1 Tryptophan halogenase Shikimate_DH PF01488.20 KLO08122.1 - 0.0038 17.3 0.2 5 7.2 0.0 3.2 3 1 1 4 4 4 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 KLO08122.1 - 0.0085 15.3 0.2 1.1 8.4 0.1 3.5 1 1 2 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KLO08122.1 - 0.0094 14.7 0.3 0.044 12.5 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein F420_oxidored PF03807.17 KLO08122.1 - 0.017 15.7 0.0 1.4 9.5 0.0 3.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.6 KLO08122.1 - 0.066 13.2 0.5 18 5.3 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding ApbA PF02558.16 KLO08122.1 - 0.093 12.4 0.5 11 5.6 0.0 2.6 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FMN_dh PF01070.18 KLO08123.1 - 1.8e-109 366.0 0.0 2.3e-109 365.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KLO08123.1 - 1.2e-06 27.8 0.7 0.00013 21.1 0.1 3.1 3 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KLO08123.1 - 0.00016 21.1 0.7 0.14 11.5 0.0 3.3 3 1 1 4 4 4 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KLO08123.1 - 0.00056 19.2 0.1 0.00099 18.3 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ALG11_N PF15924.5 KLO08124.1 - 2e-87 292.6 0.1 2.7e-87 292.2 0.1 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KLO08124.1 - 4.4e-26 91.4 0.0 6.7e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KLO08124.1 - 1.5e-13 51.3 0.1 3.6e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KLO08124.1 - 0.047 14.1 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KLO08124.1 - 0.099 12.6 0.0 0.28 11.1 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Abhydrolase_6 PF12697.7 KLO08125.1 - 1.9e-18 67.9 0.1 2.6e-18 67.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO08125.1 - 1.9e-14 53.9 0.1 4e-14 52.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO08125.1 - 8.9e-10 38.2 0.0 6e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KLO08125.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KLO08125.1 - 0.029 14.2 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KLO08125.1 - 0.047 13.2 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Yae1_N PF09811.9 KLO08127.1 - 6.6e-10 38.5 11.8 3.1e-05 23.6 0.4 2.3 1 1 1 2 2 2 2 Essential protein Yae1, N terminal DUF745 PF05335.13 KLO08127.1 - 1.9e-05 24.4 16.7 2.6e-05 24.0 16.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) V_ATPase_I PF01496.19 KLO08127.1 - 0.0039 15.2 7.6 0.0055 14.7 7.6 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ERM PF00769.19 KLO08127.1 - 0.016 15.1 19.0 0.016 15.1 19.0 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Spc7 PF08317.11 KLO08127.1 - 0.036 12.9 18.5 0.056 12.3 18.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 KLO08127.1 - 0.049 13.8 3.3 0.049 13.8 3.3 2.9 1 1 2 3 3 3 0 Haemolysin XhlA DUF724 PF05266.14 KLO08127.1 - 0.094 12.5 12.5 0.17 11.7 12.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Alanine_zipper PF11839.8 KLO08127.1 - 0.1 13.0 19.4 0.055 13.8 6.7 2.5 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein DUF641 PF04859.12 KLO08127.1 - 0.15 12.4 10.4 0.26 11.6 9.9 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) AAA_13 PF13166.6 KLO08127.1 - 0.21 10.2 7.0 0.34 9.5 7.0 1.4 1 0 0 1 1 1 0 AAA domain HAP1_N PF04849.13 KLO08127.1 - 0.39 9.9 17.4 0.55 9.4 17.4 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region MscS_porin PF12795.7 KLO08127.1 - 0.6 9.6 24.4 2.1 7.9 24.3 1.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Emaravirus_P4 PF16505.5 KLO08127.1 - 0.67 8.9 3.0 0.9 8.5 1.2 1.9 1 1 1 2 2 2 0 P4 movement protein of Emaravirus, and the 30K superfamily FUSC PF04632.12 KLO08127.1 - 0.69 8.4 11.2 0.77 8.2 11.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family T3SSipB PF16535.5 KLO08127.1 - 1 9.8 12.2 1.7 9.1 12.2 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF3450 PF11932.8 KLO08127.1 - 1.1 8.6 18.1 0.33 10.2 14.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 KLO08127.1 - 1.5 8.3 10.8 2.2 7.8 10.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 KLO08127.1 - 1.8 5.9 20.6 2.5 5.5 20.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.11 KLO08127.1 - 2.8 8.4 4.5 3.9 7.9 0.6 2.8 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.13 KLO08127.1 - 4.4 7.7 20.0 13 6.2 0.2 3.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Sad1_UNC PF07738.13 KLO08128.1 - 3.4e-29 101.5 0.1 6.7e-29 100.6 0.1 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ATP-synt_C PF00137.21 KLO08129.1 - 4.7e-34 116.5 32.6 5.8e-22 77.8 15.3 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF4577 PF15145.6 KLO08129.1 - 0.21 11.7 0.3 0.39 10.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) RCR PF12273.8 KLO08130.1 - 0.0032 18.1 0.0 0.0059 17.2 0.0 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 KLO08130.1 - 0.028 15.3 0.0 0.052 14.4 0.0 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 KLO08130.1 - 0.059 14.1 0.0 0.083 13.7 0.0 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Rax2 PF12768.7 KLO08130.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Orf78 PF06024.12 KLO08130.1 - 0.24 11.7 0.0 0.37 11.1 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) AAA PF00004.29 KLO08131.1 - 7.7e-39 133.1 0.0 1.2e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KLO08131.1 - 3.3e-10 39.6 0.0 7.5e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KLO08131.1 - 6.9e-07 29.1 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KLO08131.1 - 8.9e-06 26.2 0.1 0.0002 21.8 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KLO08131.1 - 9.7e-06 25.6 0.0 3.6e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KLO08131.1 - 2.7e-05 24.2 0.5 0.0007 19.6 0.5 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KLO08131.1 - 0.00028 21.2 0.1 0.0054 17.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KLO08131.1 - 0.0003 20.2 0.2 0.0016 17.8 0.2 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KLO08131.1 - 0.00043 20.4 0.0 0.00082 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 KLO08131.1 - 0.00073 19.5 0.1 0.0021 18.0 0.1 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 KLO08131.1 - 0.00073 20.1 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KLO08131.1 - 0.00074 19.7 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KLO08131.1 - 0.0011 19.0 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KLO08131.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KLO08131.1 - 0.0015 18.9 0.0 0.0033 17.8 0.0 1.7 2 0 0 2 2 1 1 RNA helicase TniB PF05621.11 KLO08131.1 - 0.0022 17.4 0.0 1.7 8.0 0.0 2.4 1 1 1 2 2 2 2 Bacterial TniB protein AAA_28 PF13521.6 KLO08131.1 - 0.0045 17.3 0.1 0.011 16.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 KLO08131.1 - 0.0054 16.0 0.1 0.011 14.9 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 KLO08131.1 - 0.0077 16.2 0.1 0.018 15.0 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 KLO08131.1 - 0.0079 15.9 0.1 0.015 15.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KLO08131.1 - 0.0091 15.7 0.0 0.042 13.6 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 KLO08131.1 - 0.012 15.1 0.2 0.039 13.5 0.0 1.9 3 0 0 3 3 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 KLO08131.1 - 0.015 15.7 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KLO08131.1 - 0.016 14.5 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KLO08131.1 - 0.018 14.6 0.3 0.088 12.4 0.2 2.0 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KLO08131.1 - 0.02 14.7 0.0 0.086 12.7 0.0 1.8 1 1 0 1 1 1 0 Bacterial dnaA protein TsaE PF02367.17 KLO08131.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KLO08131.1 - 0.031 14.2 0.0 0.12 12.3 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KLO08131.1 - 0.031 13.4 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 KLO08131.1 - 0.041 14.4 0.0 0.079 13.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.13 KLO08131.1 - 0.052 12.7 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CPT PF07931.12 KLO08131.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.18 KLO08131.1 - 0.055 13.2 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 KLO08131.1 - 0.07 12.5 0.0 0.76 9.1 0.0 2.0 1 1 0 2 2 2 0 KaiC AAA_3 PF07726.11 KLO08131.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KLO08131.1 - 0.094 12.5 0.1 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Guanylate_kin PF00625.21 KLO08131.1 - 0.12 12.0 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 1 0 Guanylate kinase Tetraspanin PF00335.20 KLO08132.1 - 9.9e-11 41.8 4.5 1.4e-10 41.3 4.5 1.1 1 0 0 1 1 1 1 Tetraspanin family IL4_i_Ig PF18258.1 KLO08134.1 - 0.057 13.6 0.9 12 6.2 0.2 2.4 2 0 0 2 2 2 0 Interleukin-4 inducing immunoglobulin-binding domain Cyt_b-c1_8 PF10890.8 KLO08136.1 - 0.073 13.5 0.3 1.2 9.5 0.1 2.3 1 1 1 2 2 2 0 Cytochrome b-c1 complex subunit 8 Zip PF02535.22 KLO08139.1 - 1.5e-48 165.8 19.7 2.4e-48 165.1 19.7 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4045 PF13254.6 KLO08139.1 - 2.1 7.9 6.7 3 7.4 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BTB_2 PF02214.22 KLO08143.1 - 3.8e-05 23.9 0.0 0.0006 20.1 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KLO08143.1 - 0.076 13.1 0.0 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Yae1_N PF09811.9 KLO08144.1 - 1.7e-08 34.0 7.0 2.4e-08 33.5 7.0 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Cu_amine_oxid PF01179.20 KLO08145.1 - 3.8e-151 503.7 0.0 4.7e-151 503.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KLO08145.1 - 3e-14 53.2 0.0 6.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KLO08145.1 - 0.0034 17.6 0.0 0.0068 16.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cation_ATPase PF13246.6 KLO08145.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Pro_isomerase PF00160.21 KLO08146.1 - 4.2e-47 160.3 0.3 4.8e-47 160.2 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EOS1 PF12326.8 KLO08147.1 - 1.9e-36 125.6 10.9 3.9e-32 111.6 10.0 3.3 2 2 1 3 3 3 2 N-glycosylation protein Sacchrp_dh_C PF16653.5 KLO08148.1 - 1.4e-73 248.3 0.0 2.2e-73 247.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KLO08148.1 - 1.8e-17 63.8 0.0 3.4e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 KLO08148.1 - 3.8e-07 30.5 0.0 3.5e-06 27.3 0.0 2.7 4 0 0 4 4 4 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KLO08148.1 - 0.0014 18.0 0.1 2.1 7.6 0.0 2.6 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 KLO08148.1 - 0.0077 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KLO08148.1 - 0.032 14.3 0.0 0.24 11.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ribonuclease_T2 PF00445.18 KLO08149.1 - 8.8e-38 130.4 0.2 1.6e-37 129.5 0.2 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family DUF3915 PF13054.6 KLO08149.1 - 1.3 9.0 3.6 1.3 9.0 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) SelP_N PF04592.14 KLO08149.1 - 2.9 7.2 6.8 4.6 6.6 6.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region adh_short PF00106.25 KLO08151.1 - 1.4e-30 106.3 0.1 1.8e-30 105.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO08151.1 - 9.8e-21 74.4 0.1 1.1e-20 74.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO08151.1 - 2.6e-06 27.5 0.1 3.3e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KLO08151.1 - 0.00012 22.0 0.1 0.00016 21.6 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KLO08151.1 - 0.0064 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KLO08151.1 - 0.027 13.9 0.0 0.07 12.6 0.0 1.7 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.13 KLO08152.1 - 3.5e-13 49.9 0.1 7e-12 45.7 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KLO08152.1 - 1.9e-09 37.0 0.0 1.8e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KLO08152.1 - 0.00046 19.7 0.0 0.46 9.9 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KLO08152.1 - 0.00053 19.0 0.0 0.00076 18.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KLO08152.1 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KLO08152.1 - 0.0054 16.4 0.0 0.0071 16.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO08152.1 - 0.018 15.6 0.1 0.025 15.2 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KLO08152.1 - 0.027 13.4 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DIM1 PF02966.16 KLO08153.1 - 1.3e-58 196.5 0.2 1.6e-58 196.3 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 TFIIS_M PF07500.14 KLO08154.1 - 3.5e-30 104.8 0.1 3.5e-30 104.8 0.1 2.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KLO08154.1 - 1.8e-16 59.7 8.6 2.8e-16 59.1 8.6 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KLO08154.1 - 3.6e-11 42.9 1.7 1e-10 41.5 1.7 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain FIN1 PF17300.2 KLO08154.1 - 0.052 13.1 0.2 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 HMG_box PF00505.19 KLO08154.1 - 0.25 11.8 2.9 0.23 11.9 0.5 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box Rad60-SLD PF11976.8 KLO08155.1 - 5.1e-22 77.5 0.9 6.4e-22 77.2 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KLO08155.1 - 5e-11 42.2 0.3 6.6e-11 41.8 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family TMCO5 PF14992.6 KLO08156.1 - 0.15 11.6 1.0 0.54 9.8 1.0 1.9 1 1 0 1 1 1 0 TMCO5 family adh_short PF00106.25 KLO08157.1 - 1.8e-29 102.6 0.1 2.3e-29 102.3 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO08157.1 - 5.5e-18 65.4 0.1 6.6e-18 65.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO08157.1 - 9.8e-06 25.6 0.3 1.6e-05 24.9 0.3 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KLO08157.1 - 0.008 15.4 0.1 0.05 12.8 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein DUF413 PF04219.12 KLO08157.1 - 0.074 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF DUF3072 PF11272.8 KLO08157.1 - 0.19 11.6 0.0 1.1 9.2 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3072) Abhydrolase_3 PF07859.13 KLO08158.1 - 1.6e-11 44.5 0.1 9.4e-11 42.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KLO08158.1 - 2.6e-08 33.2 0.0 1.6e-07 30.6 0.1 2.0 2 1 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 KLO08158.1 - 5.8e-05 22.7 0.0 0.00014 21.4 0.0 1.7 2 1 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KLO08158.1 - 0.00014 21.2 0.0 0.00026 20.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 KLO08158.1 - 0.00094 18.1 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KLO08158.1 - 0.0056 17.3 0.2 0.0072 17.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO08158.1 - 0.0092 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 KLO08158.1 - 0.05 13.6 0.0 0.29 11.1 0.0 2.0 1 1 1 2 2 2 0 Cutinase PCP PF02429.15 KLO08158.1 - 0.056 13.8 0.0 0.097 13.0 0.0 1.3 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein DUF2974 PF11187.8 KLO08158.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) GP40 PF11025.8 KLO08159.1 - 0.0062 16.3 7.4 0.0062 16.3 7.4 1.5 1 1 0 1 1 1 1 Glycoprotein GP40 of Cryptosporidium Inhibitor_I36 PF03995.13 KLO08160.1 - 0.038 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor family I36 ThuA PF06283.11 KLO08160.1 - 0.093 12.9 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Trehalose utilisation DPPIV_N PF00930.21 KLO08161.1 - 0.036 12.8 0.0 0.16 10.7 0.0 2.1 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Phtf-FEM1B_bdg PF12129.8 KLO08161.1 - 0.14 12.0 0.6 0.27 11.1 0.6 1.4 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor BCIP PF13862.6 KLO08164.1 - 2.7e-61 206.9 0.0 3.8e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein 2OG-FeII_Oxy PF03171.20 KLO08165.1 - 0.00017 22.1 0.0 0.00051 20.5 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KLO08165.1 - 0.00043 21.0 0.0 0.0015 19.3 0.2 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal AAA_18 PF13238.6 KLO08167.1 - 0.00013 22.6 0.0 0.021 15.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KLO08167.1 - 0.00067 19.8 0.2 0.022 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KLO08167.1 - 0.0061 15.6 0.0 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 KLO08167.1 - 0.033 13.6 0.0 0.059 12.8 0.0 1.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PRK PF00485.18 KLO08167.1 - 0.069 12.9 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 KLO08167.1 - 0.08 13.4 0.0 0.5 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain SfLAP PF11139.8 KLO08168.1 - 0.089 12.2 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein Ecl1 PF12855.7 KLO08168.1 - 0.53 11.4 16.5 0.089 13.9 8.2 2.1 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins FAD_binding_4 PF01565.23 KLO08170.1 - 2.8e-17 62.7 0.1 6.2e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KLO08170.1 - 4.1e-10 39.6 0.0 8.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like SKG6 PF08693.10 KLO08173.1 - 0.0072 15.7 0.9 0.019 14.4 0.9 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2273 PF10031.9 KLO08173.1 - 0.81 9.7 4.2 1.5 8.9 4.2 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) PTP_tm PF18861.1 KLO08173.1 - 1.8 8.5 3.5 1.5 8.8 1.1 1.9 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J SKG6 PF08693.10 KLO08174.1 - 0.004 16.5 0.3 0.007 15.8 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Hydrophobin PF01185.18 KLO08175.1 - 5.2e-09 36.6 0.4 6.4e-09 36.3 0.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin BTB PF00651.31 KLO08177.1 - 8.4e-09 35.6 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 KLO08180.1 - 3.5e-06 26.8 0.0 8.8e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF3996 PF13161.6 KLO08181.1 - 0.083 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3996) BTB PF00651.31 KLO08182.1 - 0.00031 20.9 0.1 0.00065 19.9 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Bromodomain PF00439.25 KLO08183.1 - 1.1e-29 102.4 0.8 4.9e-19 68.2 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KLO08183.1 - 3e-09 36.8 0.0 5.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 BAH domain Sec31 PF11549.8 KLO08184.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein transport protein SEC31 WD40 PF00400.32 KLO08185.1 - 4.6e-30 103.2 15.1 4.7e-06 27.2 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 KLO08185.1 - 7e-10 38.2 0.9 0.0011 17.7 0.1 3.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KLO08185.1 - 0.0029 17.9 0.0 22 5.4 0.0 3.9 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain HAP1_N PF04849.13 KLO08185.1 - 0.011 15.0 4.3 0.018 14.3 4.3 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region BC10 PF06726.12 KLO08186.1 - 2.1e-11 43.9 10.5 3.7e-11 43.1 10.5 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 RNA_pol_3_Rpc31 PF11705.8 KLO08202.1 - 0.037 14.3 7.9 0.046 14.0 7.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 KLO08202.1 - 0.22 9.7 8.2 0.23 9.7 8.2 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KLO08202.1 - 0.54 9.8 5.7 0.67 9.5 5.7 1.1 1 0 0 1 1 1 0 PPP4R2 TRAP_alpha PF03896.16 KLO08202.1 - 1.7 7.8 4.4 2.1 7.5 4.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 KLO08202.1 - 1.8 6.8 6.5 2 6.6 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KLO08202.1 - 6.8 5.9 16.8 13 5.0 16.8 1.5 1 1 0 1 1 1 0 NOA36 protein BTB PF00651.31 KLO08207.1 - 5.1e-05 23.5 0.1 7.6e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.25 KLO08209.1 - 2.2e-34 119.1 0.0 2.8e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08209.1 - 2.8e-29 102.2 0.0 3.7e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KLO08209.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KLO08209.1 - 0.049 12.4 0.0 0.069 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KLO08209.1 - 0.075 12.9 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 KLO08209.1 - 0.15 12.2 0.0 0.47 10.6 0.0 1.7 1 1 1 2 2 2 0 ABC1 family Pox_ser-thr_kin PF05445.11 KLO08209.1 - 0.24 10.3 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase UvdE PF03851.14 KLO08210.1 - 6e-78 261.9 0.1 5.3e-67 226.0 0.0 2.8 2 1 0 2 2 2 2 UV-endonuclease UvdE AP_endonuc_2 PF01261.24 KLO08210.1 - 0.00041 19.9 0.0 0.00076 19.0 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel BTB PF00651.31 KLO08211.1 - 1.5e-08 34.8 0.3 1.2e-07 31.9 0.3 2.0 1 1 0 1 1 1 1 BTB/POZ domain CDP-OH_P_transf PF01066.21 KLO08212.1 - 1.3e-15 57.9 0.3 1.3e-15 57.9 0.3 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pkinase_Tyr PF07714.17 KLO08214.1 - 4.5e-32 111.4 0.0 6.5e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08214.1 - 3.7e-29 101.9 0.0 5.2e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO08214.1 - 0.00027 20.3 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO08214.1 - 0.0014 18.6 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KLO08214.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KLO08214.1 - 0.087 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KLO08214.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Oxidored_molyb PF00174.19 KLO08215.1 - 4.3e-46 156.7 0.0 7.9e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KLO08215.1 - 6.8e-20 71.5 1.6 1.3e-19 70.6 1.6 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Pkinase_Tyr PF07714.17 KLO08218.1 - 1.8e-27 96.3 0.0 1.3e-25 90.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KLO08218.1 - 4.3e-25 88.6 0.0 1.5e-23 83.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 KLO08218.1 - 0.0066 15.8 0.0 0.0099 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KLO08218.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KLO08218.1 - 0.046 13.6 0.1 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO08218.1 - 0.088 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Oxidored_molyb PF00174.19 KLO08219.1 - 2.1e-16 60.0 0.0 4.6e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KLO08219.1 - 1.8e-15 57.1 0.9 5.8e-15 55.5 0.3 2.1 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Pkinase_Tyr PF07714.17 KLO08220.1 - 4.8e-19 68.7 0.0 6.3e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08220.1 - 1.1e-18 67.6 0.0 1.4e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KLO08220.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Cation_efflux PF01545.21 KLO08221.1 - 6.8e-46 156.5 3.3 2.3e-45 154.8 3.3 1.8 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KLO08221.1 - 6.3e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 KLO08223.1 - 0.0017 18.1 0.1 0.0019 18.0 0.1 1.0 1 0 0 1 1 1 1 Cation efflux family F-box-like PF12937.7 KLO08224.1 - 3.1e-06 27.0 1.2 0.00059 19.7 0.0 2.7 2 0 0 2 2 2 2 F-box-like Pkinase PF00069.25 KLO08225.1 - 3.9e-39 134.6 0.0 5.3e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08225.1 - 9.7e-36 123.4 0.0 1.2e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Zn_clus PF00172.18 KLO08225.1 - 0.00015 21.8 11.3 0.00027 21.0 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase_fungal PF17667.1 KLO08225.1 - 0.0018 17.1 0.0 0.0026 16.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO08225.1 - 0.0089 15.4 0.1 0.019 14.3 0.1 1.5 1 1 0 1 1 1 1 Kinase-like DUF309 PF03745.14 KLO08225.1 - 0.055 13.2 0.0 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF309) RIO1 PF01163.22 KLO08225.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family F-box-like PF12937.7 KLO08226.1 - 1.8e-07 31.0 0.1 8.2e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO08227.1 - 8.5e-05 22.4 0.1 0.00077 19.3 0.0 2.5 2 0 0 2 2 2 1 F-box-like p450 PF00067.22 KLO08228.1 - 1.6e-66 225.0 0.0 2.3e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KLO08228.1 - 1.4e-28 100.0 0.0 2.3e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KLO08228.1 - 2.6e-22 79.6 0.0 5.5e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KLO08228.1 - 3.3e-11 43.8 0.0 9.5e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain adh_short_C2 PF13561.6 KLO08229.1 - 2.9e-23 82.7 0.1 3.5e-23 82.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO08229.1 - 1.8e-16 60.2 0.1 2.2e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO08229.1 - 0.00038 20.4 0.3 0.00054 19.9 0.3 1.2 1 0 0 1 1 1 1 KR domain F-box-like PF12937.7 KLO08230.1 - 2.5e-06 27.3 0.1 5.7e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO08230.1 - 1.5 8.8 4.4 23 5.0 4.4 2.9 1 1 0 1 1 1 0 F-box domain adh_short_C2 PF13561.6 KLO08231.1 - 2.7e-29 102.4 0.0 3.2e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO08231.1 - 1e-19 70.8 0.0 1.3e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO08231.1 - 0.0021 18.0 0.1 0.0031 17.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KLO08231.1 - 0.047 12.8 0.2 0.07 12.2 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PRANC PF09372.10 KLO08231.1 - 0.06 13.7 0.0 0.14 12.5 0.0 1.6 2 0 0 2 2 2 0 PRANC domain NAD_binding_7 PF13241.6 KLO08231.1 - 0.11 13.0 0.9 0.81 10.2 0.3 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding adh_short_C2 PF13561.6 KLO08232.1 - 8.4e-28 97.5 0.1 1.1e-27 97.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO08232.1 - 6.3e-19 68.2 0.0 7.7e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO08232.1 - 2.5e-05 24.3 0.1 3.5e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KLO08232.1 - 0.018 15.3 0.3 0.031 14.5 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KLO08232.1 - 0.022 15.2 1.2 0.073 13.5 0.5 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.15 KLO08232.1 - 0.044 12.9 0.1 0.065 12.3 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein QRPTase_C PF01729.19 KLO08232.1 - 0.057 13.2 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain adh_short_C2 PF13561.6 KLO08233.1 - 8.7e-27 94.2 0.0 1.1e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO08233.1 - 4.7e-20 71.9 0.0 5.6e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO08233.1 - 1.1e-06 28.7 0.2 1.8e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KLO08233.1 - 0.1 11.7 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 KLO08233.1 - 0.11 13.0 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Glyco_hydro_3 PF00933.21 KLO08234.1 - 1.5e-59 202.0 0.0 2e-59 201.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KLO08234.1 - 5.2e-49 167.0 0.0 9.4e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KLO08234.1 - 4.9e-21 74.6 0.1 1.3e-20 73.3 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.18 KLO08234.1 - 0.0023 18.2 0.9 0.011 16.0 0.9 2.2 1 0 0 1 1 1 1 Domain of unknown function DUF11 fn3_5 PF06280.12 KLO08234.1 - 0.037 14.7 4.5 2.3 8.9 2.3 3.3 2 1 1 3 3 3 0 Fn3-like domain DUF5001 PF16392.5 KLO08234.1 - 0.27 11.2 1.1 3.7 7.5 0.0 3.0 3 0 0 3 3 3 0 Ig-like domain CARDB PF07705.11 KLO08234.1 - 0.72 10.1 8.1 0.27 11.5 2.4 2.9 2 1 1 3 3 3 0 CARDB LRR_4 PF12799.7 KLO08235.1 - 0.0096 16.3 9.9 0.16 12.4 1.0 4.2 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO08235.1 - 0.047 13.6 1.3 0.11 12.4 1.3 1.6 1 0 0 1 1 1 0 F-box-like NIF3 PF01784.18 KLO08236.1 - 9e-53 179.4 0.0 1.1e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DDE_1 PF03184.19 KLO08238.1 - 9.7e-22 77.5 0.0 2.6e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO08238.1 - 0.0049 16.6 0.1 0.083 12.6 0.0 2.4 2 1 0 2 2 2 1 DDE superfamily endonuclease RNA_pol_L_2 PF13656.6 KLO08239.1 - 7.7e-12 44.8 0.0 1.1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KLO08239.1 - 7.2e-05 22.1 0.0 9.3e-05 21.8 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ion_trans PF00520.31 KLO08240.1 - 6.8e-23 81.2 18.1 8.4e-23 80.9 18.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KLO08240.1 - 7e-13 48.4 3.3 7e-13 48.4 3.3 2.7 2 0 0 2 2 2 1 Ion channel DUF2614 PF11023.8 KLO08240.1 - 7.2 6.8 9.0 2 8.5 4.9 2.2 1 1 0 1 1 1 0 Zinc-ribbon containing domain DUF3693 PF12472.8 KLO08241.1 - 0.26 11.0 1.7 0.5 10.1 1.7 1.5 1 0 0 1 1 1 0 Phage related protein DUF3713 PF12506.8 KLO08241.1 - 9.3 6.6 9.9 7.6 6.9 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3713) Glyco_transf_4 PF13439.6 KLO08242.1 - 0.04 13.9 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DDE_1 PF03184.19 KLO08249.1 - 1.5e-11 44.3 0.0 2.5e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO08249.1 - 0.021 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF1298 PF06974.13 KLO08254.1 - 0.028 14.4 0.8 2.9 7.8 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1298) NitrOD2 PF18550.1 KLO08260.1 - 0.071 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Nitrososphaera output domain 2 DUF5614 PF18474.1 KLO08260.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5614) DUF1962 PF09227.10 KLO08260.1 - 0.22 11.9 0.0 0.67 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1962) Plavaka PF18759.1 KLO08261.1 - 1.9e-32 112.8 0.1 1.9e-32 112.8 0.1 1.5 2 0 0 2 2 2 1 Plavaka transposase EF-hand_1 PF00036.32 KLO08262.1 - 4.8e-24 82.1 13.7 1.9e-05 23.8 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KLO08262.1 - 1.5e-21 76.6 5.3 1.3e-11 44.8 2.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KLO08262.1 - 8.7e-18 62.7 9.0 0.001 18.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KLO08262.1 - 1.7e-17 62.0 12.9 0.00011 21.6 0.8 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KLO08262.1 - 1.4e-11 44.1 14.4 0.00026 20.8 3.4 4.4 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KLO08262.1 - 5.2e-06 26.8 0.0 0.094 13.0 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KLO08262.1 - 0.00016 21.6 7.2 0.032 14.2 1.3 3.7 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KLO08262.1 - 0.06 13.7 0.0 5.3 7.4 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain HTH_37 PF13744.6 KLO08263.1 - 0.075 13.0 0.3 0.16 12.0 0.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain COP-gamma_platf PF08752.10 KLO08263.1 - 0.081 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain Macoilin PF09726.9 KLO08263.1 - 1.5 7.3 5.6 2 6.9 5.6 1.2 1 0 0 1 1 1 0 Macoilin family Pap_E4 PF02711.14 KLO08263.1 - 2.5 9.1 7.1 0.74 10.8 3.3 2.1 1 1 0 2 2 2 0 E4 protein ADH_zinc_N PF00107.26 KLO08265.1 - 1.7e-08 34.5 0.3 2.9e-08 33.7 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO08265.1 - 6.6e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FAD_binding_4 PF01565.23 KLO08265.1 - 0.073 12.8 1.2 0.15 11.8 1.2 1.5 1 0 0 1 1 1 0 FAD binding domain DnaJ PF00226.31 KLO08266.1 - 2.6e-16 59.5 0.0 4.3e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Gln-synt_C PF00120.24 KLO08267.1 - 7.9e-16 58.0 0.0 1.6e-13 50.4 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KLO08267.1 - 1.1e-10 41.1 0.0 1.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SLS PF14611.6 KLO08267.1 - 0.23 11.3 0.1 0.43 10.4 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator HABP4_PAI-RBP1 PF04774.15 KLO08268.1 - 0.098 13.5 2.1 0.23 12.3 2.1 1.5 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family MnmE_helical PF12631.7 KLO08269.1 - 2.5e-39 135.6 0.1 5e-39 134.6 0.1 1.5 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KLO08269.1 - 1.6e-34 118.7 0.0 4e-34 117.4 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KLO08269.1 - 1.5e-17 63.7 0.1 4.9e-17 62.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KLO08269.1 - 3.3e-06 26.7 0.0 6.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B ADH_zinc_N_2 PF13602.6 KLO08269.1 - 0.00014 22.9 0.1 0.00078 20.5 0.0 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase RsgA_GTPase PF03193.16 KLO08269.1 - 0.028 14.3 0.1 0.08 12.8 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 KLO08269.1 - 0.033 14.2 0.0 0.088 12.9 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AIG1 PF04548.16 KLO08269.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family GN3L_Grn1 PF08701.11 KLO08270.1 - 3.9e-24 84.5 24.7 3.9e-24 84.5 24.7 2.7 2 1 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KLO08270.1 - 4.2e-12 46.2 0.8 1.5e-08 34.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.16 KLO08270.1 - 4.4e-07 29.4 0.0 4.4e-07 29.4 0.0 2.5 3 0 0 3 3 3 1 AIG1 family GTP_EFTU PF00009.27 KLO08270.1 - 2.6e-05 23.8 0.1 0.014 14.9 0.0 3.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KLO08270.1 - 6.8e-05 23.0 0.1 6.8e-05 23.0 0.1 4.0 3 1 0 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 KLO08270.1 - 0.00013 21.9 0.7 0.069 13.1 0.1 2.4 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KLO08270.1 - 0.0021 17.6 0.1 0.073 12.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.18 KLO08270.1 - 0.011 15.0 0.0 0.03 13.6 0.0 1.7 1 0 0 1 1 1 0 Septin BUD22 PF09073.10 KLO08270.1 - 3.1 7.1 41.9 0.37 10.1 19.8 2.3 2 0 0 2 2 2 0 BUD22 Efg1 PF10153.9 KLO08271.1 - 4.5e-36 123.7 7.4 4.5e-36 123.7 7.4 2.2 3 0 0 3 3 3 1 rRNA-processing protein Efg1 FlgM PF04316.13 KLO08271.1 - 0.34 11.3 2.9 1.6 9.2 0.2 2.9 3 1 0 3 3 3 0 Anti-sigma-28 factor, FlgM RNB PF00773.19 KLO08272.1 - 2.6e-103 345.8 0.3 5.1e-103 344.8 0.3 1.5 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 KLO08272.1 - 7.7e-26 90.3 0.1 2.2e-25 88.8 0.1 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 KLO08272.1 - 8.6e-25 86.6 0.0 1.8e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_S1 PF17215.3 KLO08272.1 - 0.00064 19.6 0.0 0.0026 17.7 0.0 2.1 1 1 0 1 1 1 1 S1 domain CSD2 PF17876.1 KLO08272.1 - 0.00064 19.8 0.0 0.28 11.4 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KLO08272.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain BAF1_ABF1 PF04684.13 KLO08272.1 - 0.64 9.0 8.2 2.9 6.8 0.2 2.7 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor Iso_dh PF00180.20 KLO08273.1 - 2.4e-100 336.1 0.0 3e-100 335.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Snf7 PF03357.21 KLO08275.1 - 7.6e-28 97.2 19.6 7.6e-28 97.2 19.6 1.6 1 1 0 1 1 1 1 Snf7 T3SS_needle_E PF08988.10 KLO08275.1 - 0.67 10.1 5.9 0.31 11.2 0.6 2.7 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Vps51 PF08700.11 KLO08275.1 - 0.79 9.8 0.0 0.79 9.8 0.0 3.4 3 1 0 3 3 3 0 Vps51/Vps67 Plasmid_RAQPRD PF09686.10 KLO08275.1 - 1.2 9.3 9.0 8.6 6.7 0.9 2.7 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) GPI-anchored PF10342.9 KLO08276.1 - 1.3e-11 45.1 3.0 2e-11 44.5 3.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Med17 PF10156.9 KLO08277.1 - 4.5e-46 157.5 0.0 5.5e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Fungal_trans PF04082.18 KLO08278.1 - 1.4e-16 60.3 0.0 2.4e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO08278.1 - 3.6e-05 23.8 9.9 6e-05 23.1 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fibrinogen_BP PF08017.11 KLO08278.1 - 0.042 12.3 0.1 0.073 11.5 0.1 1.3 1 0 0 1 1 1 0 Fibrinogen binding protein VID27 PF08553.10 KLO08280.1 - 5.1e-153 509.3 1.5 6.5e-153 509.0 1.5 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KLO08280.1 - 3.4e-50 170.2 0.5 5.6e-49 166.3 0.0 2.5 2 0 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 KLO08280.1 - 5e-26 91.1 1.4 4.5e-25 88.1 1.1 2.5 3 0 0 3 3 3 1 VID27 PH-like domain DUF3605 PF12239.8 KLO08281.1 - 5.6e-28 98.2 0.0 9.7e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) Clat_adaptor_s PF01217.20 KLO08283.1 - 8.1e-56 187.9 1.6 9.4e-56 187.7 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.11 KLO08283.1 - 0.034 13.6 0.6 0.28 10.6 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1204) Zn_clus PF00172.18 KLO08284.1 - 0.00025 21.1 6.9 0.00025 21.1 6.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHORD PF04968.12 KLO08284.1 - 0.0039 17.9 4.0 0.0087 16.8 4.0 1.6 1 0 0 1 1 1 1 CHORD TRAM_LAG1_CLN8 PF03798.16 KLO08285.1 - 2.8e-34 118.6 27.5 2.8e-34 118.6 27.5 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KLO08285.1 - 2.8e-15 55.7 0.1 2.8e-15 55.7 0.1 2.0 2 0 0 2 2 2 1 TRAM1-like protein F-box-like PF12937.7 KLO08286.1 - 5e-08 32.7 0.2 1.1e-07 31.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO08286.1 - 0.0011 18.8 0.0 0.0039 17.0 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 KLO08286.1 - 0.0081 16.1 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like domain F-box-like PF12937.7 KLO08287.1 - 5.1e-06 26.3 0.0 1.5e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08288.1 - 1.9e-07 30.8 0.0 3.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08289.1 - 0.00011 22.1 0.0 0.00026 20.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like zf-HYPF PF07503.12 KLO08290.1 - 0.0078 16.0 0.0 0.091 12.5 0.0 2.4 2 0 0 2 2 2 1 HypF finger WAK PF08488.11 KLO08290.1 - 0.044 14.3 0.0 0.18 12.3 0.0 1.9 2 0 0 2 2 2 0 Wall-associated kinase BAAT_C PF08840.11 KLO08290.1 - 0.056 13.4 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal HTH_Crp_2 PF13545.6 KLO08290.1 - 0.071 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain F-box-like PF12937.7 KLO08291.1 - 5.9e-06 26.1 0.0 1.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08292.1 - 3.3e-07 30.1 0.0 9.3e-07 28.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08293.1 - 4.2e-06 26.5 0.0 1.2e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF444 PF04285.12 KLO08293.1 - 0.24 10.4 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF444) F-box-like PF12937.7 KLO08294.1 - 3e-06 27.0 0.0 6.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08295.1 - 1.8e-07 30.9 0.0 5e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08296.1 - 2.1e-07 30.7 0.1 6.6e-07 29.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08297.1 - 1.5e-07 31.2 0.1 5.6e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO08297.1 - 0.019 15.4 8.3 16 6.1 0.0 5.2 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO08299.1 - 1.8e-10 40.5 0.1 4.2e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO08299.1 - 0.0088 15.9 0.3 0.2 11.6 0.3 2.6 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO08300.1 - 5e-08 32.7 0.1 1.7e-06 27.8 0.0 2.7 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO08301.1 - 1.1e-07 31.6 0.0 3.4e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO08302.1 - 1.2e-08 34.7 0.0 3.4e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08303.1 - 4.2e-08 33.0 0.4 2e-05 24.4 0.0 3.4 3 0 0 3 3 3 2 F-box-like F-box-like PF12937.7 KLO08304.1 - 1.1e-05 25.2 0.1 3.1e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO08304.1 - 0.14 12.7 0.3 21 5.7 0.1 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO08305.1 - 3e-07 30.2 0.0 6.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO08305.1 - 0.015 15.1 0.0 0.05 13.5 0.0 1.9 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO08307.1 - 7.5e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08308.1 - 2.7e-08 33.6 0.0 7.3e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like CMS1 PF14617.6 KLO08308.1 - 0.13 11.6 0.0 0.94 8.8 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit F-box-like PF12937.7 KLO08309.1 - 5.1e-09 35.9 0.1 2.6e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 F-box-like SeqA_N PF17206.3 KLO08309.1 - 0.019 14.2 0.0 0.046 13.0 0.0 1.6 1 0 0 1 1 1 0 SeqA protein N-terminal domain LRR_4 PF12799.7 KLO08309.1 - 0.8 10.2 6.9 24 5.5 0.1 4.6 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO08310.1 - 2.8e-06 27.1 1.4 6.8e-06 25.9 0.0 2.5 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.7 KLO08312.1 - 3.7e-07 29.9 0.0 1.4e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like DUF4760 PF15956.5 KLO08312.1 - 0.091 12.9 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4760) F-box-like PF12937.7 KLO08313.1 - 2.2e-07 30.6 0.1 5.8e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 KLO08314.1 - 6.3e-45 150.3 21.6 6.8e-12 45.7 0.1 8.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO08314.1 - 3e-15 56.3 0.8 6.1e-05 23.2 0.0 6.4 2 1 6 8 8 7 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KLO08314.1 - 4.2e-12 46.3 0.0 0.00029 20.8 0.0 3.8 2 2 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO08314.1 - 9.2e-10 39.2 0.0 0.00054 20.4 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.22 KLO08314.1 - 3.7e-09 36.2 0.0 9e-06 25.1 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.6 KLO08314.1 - 8e-09 35.9 0.0 0.0055 17.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KLO08314.1 - 7.5e-08 31.9 0.0 0.0098 15.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.29 KLO08314.1 - 1.9e-07 31.5 0.0 0.0083 16.5 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KLO08314.1 - 1.3e-05 25.1 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase RNA_helicase PF00910.22 KLO08314.1 - 1.4e-05 25.4 0.0 0.29 11.5 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_18 PF13238.6 KLO08314.1 - 2.1e-05 25.1 0.0 0.24 12.0 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KLO08314.1 - 2.6e-05 23.9 0.1 0.11 12.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 KLO08314.1 - 0.0002 20.7 0.0 0.34 10.1 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Ploopntkinase3 PF18751.1 KLO08314.1 - 0.00043 20.2 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 KLO08314.1 - 0.00044 20.0 0.0 0.12 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KLO08314.1 - 0.00075 18.8 3.8 0.89 8.7 0.1 4.0 4 1 0 4 4 4 2 KAP family P-loop domain Rad17 PF03215.15 KLO08314.1 - 0.00077 19.4 0.2 0.36 10.7 0.0 3.3 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_33 PF13671.6 KLO08314.1 - 0.0011 19.1 0.0 0.36 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KLO08314.1 - 0.0014 19.1 0.0 0.24 11.9 0.0 2.7 2 0 0 2 2 2 1 ABC transporter Parvo_NS1 PF01057.17 KLO08314.1 - 0.0019 17.3 1.6 0.09 11.8 0.1 2.9 3 0 0 3 3 3 1 Parvovirus non-structural protein NS1 ResIII PF04851.15 KLO08314.1 - 0.0026 17.8 0.0 0.083 12.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KLO08314.1 - 0.0028 17.4 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Ge1_WD40 PF16529.5 KLO08314.1 - 0.0038 16.2 0.4 4.5 6.1 0.0 4.8 2 1 4 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PPV_E1_C PF00519.17 KLO08314.1 - 0.0045 15.9 0.0 1.9 7.2 0.0 2.4 2 0 0 2 2 2 1 Papillomavirus helicase IstB_IS21 PF01695.17 KLO08314.1 - 0.005 16.6 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase_2 PF01637.18 KLO08314.1 - 0.0052 16.7 0.0 0.14 12.0 0.0 2.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KLO08314.1 - 0.0054 17.1 0.0 0.42 10.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KLO08314.1 - 0.0071 16.1 0.0 0.42 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain NBD94 PF16830.5 KLO08314.1 - 0.01 16.2 0.0 2.8 8.4 0.0 2.8 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH AAA_28 PF13521.6 KLO08314.1 - 0.012 15.8 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KLO08314.1 - 0.018 15.5 0.1 2 8.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Nbas_N PF15492.6 KLO08314.1 - 0.019 14.3 0.5 0.42 9.9 0.0 2.9 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal TIP49 PF06068.13 KLO08314.1 - 0.019 14.2 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_14 PF13173.6 KLO08314.1 - 0.022 14.8 0.0 2.4 8.2 0.0 3.4 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KLO08314.1 - 0.041 13.4 0.0 0.53 9.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KLO08314.1 - 0.046 13.1 0.0 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KLO08314.1 - 0.057 13.2 0.0 8.4 6.2 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KLO08314.1 - 0.061 13.3 0.0 2 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KLO08314.1 - 0.061 13.2 0.0 0.74 9.7 0.0 2.3 2 0 0 2 2 2 0 NTPase Nup160 PF11715.8 KLO08314.1 - 0.066 11.8 0.3 2.2 6.8 0.0 2.5 2 1 0 2 2 2 0 Nucleoporin Nup120/160 AAA_PrkA PF08298.11 KLO08314.1 - 0.068 12.1 0.0 0.98 8.3 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain DUF1904 PF08921.11 KLO08314.1 - 0.071 13.4 0.0 5.4 7.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) MeaB PF03308.16 KLO08314.1 - 0.076 12.0 0.0 3.9 6.4 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KLO08314.1 - 0.078 13.1 0.0 5.3 7.2 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RuvB_N PF05496.12 KLO08314.1 - 0.11 12.3 0.0 0.98 9.2 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Torsin PF06309.11 KLO08314.1 - 0.12 12.5 0.0 17 5.5 0.0 2.6 2 0 0 2 2 2 0 Torsin TniB PF05621.11 KLO08314.1 - 0.13 11.7 0.1 11 5.4 0.0 3.4 3 0 0 3 3 3 0 Bacterial TniB protein AAA_23 PF13476.6 KLO08314.1 - 0.16 12.5 0.7 3.8 8.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain zf-C2H2 PF00096.26 KLO08316.1 - 3.7e-06 27.1 9.4 0.011 16.2 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO08316.1 - 4.1e-06 27.2 10.2 0.017 15.9 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KLO08316.1 - 0.0062 16.9 0.2 0.42 11.1 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KLO08316.1 - 0.067 13.7 12.2 0.5 10.9 0.6 3.9 4 0 0 4 4 4 0 Zinc-finger double domain DBD_Tnp_Mut PF03108.15 KLO08316.1 - 0.07 13.1 0.3 0.47 10.5 0.1 2.2 1 1 1 2 2 2 0 MuDR family transposase IBR PF01485.21 KLO08316.1 - 0.14 12.4 4.3 0.26 11.5 0.6 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain AbLIM_anchor PF16182.5 KLO08316.1 - 0.2 11.4 10.1 0.3 10.9 10.1 1.3 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM zf-H2C2_5 PF13909.6 KLO08316.1 - 0.36 10.6 4.7 0.36 10.6 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain PAP1 PF08601.10 KLO08316.1 - 0.52 10.0 7.3 0.97 9.1 7.3 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 WD40 PF00400.32 KLO08317.1 - 6.1e-46 153.5 26.4 8.9e-11 42.2 0.7 8.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO08317.1 - 2.6e-17 62.9 0.0 0.00084 19.6 0.0 5.7 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 KLO08317.1 - 1.2e-12 48.3 0.0 9.4e-06 25.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KLO08317.1 - 2.7e-10 40.4 0.1 7.5e-06 26.0 0.0 3.5 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO08317.1 - 8.4e-09 36.0 0.0 0.0068 16.8 0.0 3.5 3 2 1 4 4 2 2 AAA ATPase domain Ge1_WD40 PF16529.5 KLO08317.1 - 1.2e-07 31.1 1.1 0.22 10.5 0.0 5.2 2 1 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Zeta_toxin PF06414.12 KLO08317.1 - 1.4e-07 31.0 0.0 0.004 16.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.29 KLO08317.1 - 1.6e-07 31.8 0.0 0.022 15.2 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KLO08317.1 - 2.2e-07 30.3 0.1 0.0013 18.0 0.0 3.7 4 0 0 4 4 3 1 NB-ARC domain APS_kinase PF01583.20 KLO08317.1 - 7.1e-07 29.3 0.1 0.078 12.9 0.0 3.3 3 0 0 3 3 3 2 Adenylylsulphate kinase AAA_18 PF13238.6 KLO08317.1 - 1.9e-06 28.4 0.0 0.12 12.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KLO08317.1 - 8.7e-06 26.1 0.0 0.34 11.3 0.0 3.2 2 0 0 2 2 2 2 RNA helicase PD40 PF07676.12 KLO08317.1 - 2.7e-05 24.0 0.9 5.4 7.1 0.0 5.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat AAA_33 PF13671.6 KLO08317.1 - 4.5e-05 23.6 0.1 0.49 10.5 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KLO08317.1 - 0.00019 21.7 0.1 0.86 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Nbas_N PF15492.6 KLO08317.1 - 0.00021 20.8 0.5 7.8 5.7 0.0 3.8 3 2 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF2075 PF09848.9 KLO08317.1 - 0.0004 19.7 0.0 0.77 8.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 KLO08317.1 - 0.00097 19.1 0.1 1.6 8.6 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_24 PF13479.6 KLO08317.1 - 0.0011 18.7 0.0 0.76 9.5 0.1 3.2 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KLO08317.1 - 0.002 18.6 0.0 0.74 10.3 0.0 2.7 2 0 0 2 2 2 1 ABC transporter Viral_helicase1 PF01443.18 KLO08317.1 - 0.0021 17.8 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Ploopntkinase3 PF18751.1 KLO08317.1 - 0.0025 17.7 0.0 0.54 10.1 0.0 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 KLO08317.1 - 0.0036 16.9 0.1 0.87 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KLO08317.1 - 0.0036 17.0 0.0 4 7.1 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 KLO08317.1 - 0.0059 16.4 0.2 0.14 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KLO08317.1 - 0.006 16.3 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KLO08317.1 - 0.01 15.9 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KLO08317.1 - 0.01 16.2 0.0 0.33 11.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KLO08317.1 - 0.012 14.7 0.1 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.15 KLO08317.1 - 0.016 15.1 0.0 0.31 10.9 0.0 2.5 2 0 0 2 2 2 0 NTPase eIF2A PF08662.11 KLO08317.1 - 0.02 14.8 0.0 0.073 12.9 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Torsin PF06309.11 KLO08317.1 - 0.02 15.0 0.0 8.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Torsin AAA_17 PF13207.6 KLO08317.1 - 0.021 15.2 1.5 2.5 8.5 0.2 2.9 2 0 0 2 2 2 0 AAA domain WD40_like PF17005.5 KLO08317.1 - 0.027 13.8 0.0 7.2 5.8 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain AAA_5 PF07728.14 KLO08317.1 - 0.044 13.8 0.0 6.2 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) B_lectin PF01453.24 KLO08317.1 - 0.045 14.3 0.0 0.32 11.6 0.0 2.5 2 0 0 2 2 1 0 D-mannose binding lectin AAA_14 PF13173.6 KLO08317.1 - 0.049 13.7 0.0 13 5.8 0.0 3.6 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KLO08317.1 - 0.059 13.5 0.0 6.9 6.8 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.13 KLO08317.1 - 0.061 12.5 0.0 8.2 5.5 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain MeaB PF03308.16 KLO08317.1 - 0.077 12.0 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 KLO08317.1 - 0.14 11.5 0.1 2.6 7.3 0.0 2.5 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 KLO08317.1 - 0.16 11.3 0.1 17 4.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 KLO08317.1 - 0.17 11.5 0.6 0.75 9.4 0.0 2.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ADK PF00406.22 KLO08317.1 - 0.24 11.5 0.7 9 6.4 0.1 2.7 2 0 0 2 2 2 0 Adenylate kinase Hydin_ADK PF17213.3 KLO08317.1 - 0.66 10.2 2.0 7.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NOZZLE PF08744.10 KLO08318.1 - 0.086 12.3 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 Plant transcription factor NOZZLE WD40 PF00400.32 KLO08319.1 - 3.1e-46 154.4 30.8 2.6e-08 34.4 0.6 8.3 8 0 0 8 8 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO08319.1 - 4.4e-20 71.8 0.3 0.11 12.9 0.0 7.8 2 1 5 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 KLO08319.1 - 1.2e-10 41.8 0.0 0.00015 22.0 0.0 3.8 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KLO08319.1 - 2.2e-09 37.5 3.4 0.0012 18.8 0.1 4.2 2 2 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO08319.1 - 8.9e-09 35.9 0.0 0.00088 19.7 0.0 3.6 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KLO08319.1 - 9e-09 35.9 0.0 0.0046 17.4 0.0 3.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KLO08319.1 - 6.1e-08 32.2 0.0 1.7e-05 24.2 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.12 KLO08319.1 - 1.4e-06 27.7 0.0 0.01 15.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Ge1_WD40 PF16529.5 KLO08319.1 - 2.2e-06 26.9 1.6 3.1 6.7 0.2 5.7 1 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RNA_helicase PF00910.22 KLO08319.1 - 5.3e-06 26.8 0.0 0.14 12.6 0.0 3.5 3 0 0 3 3 3 2 RNA helicase AAA_33 PF13671.6 KLO08319.1 - 5.6e-05 23.3 0.0 0.33 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KLO08319.1 - 8.5e-05 22.0 0.0 0.099 11.9 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KLO08319.1 - 0.00018 22.0 0.0 0.16 12.5 0.0 3.2 2 0 0 2 2 2 1 ABC transporter APS_kinase PF01583.20 KLO08319.1 - 0.00021 21.2 0.1 0.46 10.4 0.0 2.9 3 0 0 3 3 2 2 Adenylylsulphate kinase AAA_18 PF13238.6 KLO08319.1 - 0.00022 21.7 0.0 1.5 9.3 0.1 3.5 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KLO08319.1 - 0.00035 20.3 0.0 0.42 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KLO08319.1 - 0.0004 20.4 0.0 0.021 14.7 0.0 2.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Ploopntkinase3 PF18751.1 KLO08319.1 - 0.00055 19.9 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 ResIII PF04851.15 KLO08319.1 - 0.00086 19.4 0.0 0.037 14.0 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KLO08319.1 - 0.0019 18.3 0.1 0.69 10.0 0.0 3.8 3 1 0 3 3 2 1 AAA domain PD40 PF07676.12 KLO08319.1 - 0.0022 17.9 1.3 8.3 6.5 0.0 4.9 6 0 0 6 6 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KLO08319.1 - 0.0028 17.1 1.0 2.4 7.4 0.0 3.5 2 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal AAA_19 PF13245.6 KLO08319.1 - 0.0029 18.0 2.1 0.15 12.4 0.1 3.6 3 1 0 3 3 2 1 AAA domain AAA_17 PF13207.6 KLO08319.1 - 0.003 18.0 0.1 3 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KLO08319.1 - 0.0084 15.7 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 KLO08319.1 - 0.0086 15.0 0.0 0.05 12.5 0.0 2.0 2 0 0 2 2 2 1 PrkA AAA domain AAA_28 PF13521.6 KLO08319.1 - 0.0097 16.2 0.0 5.9 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF1513 PF07433.11 KLO08319.1 - 0.015 14.4 0.0 0.34 9.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) KAP_NTPase PF07693.14 KLO08319.1 - 0.016 14.4 0.4 5.9 6.0 0.0 3.4 3 0 0 3 3 3 0 KAP family P-loop domain Parvo_NS1 PF01057.17 KLO08319.1 - 0.017 14.2 0.0 2 7.5 0.0 2.9 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 KLO08319.1 - 0.018 14.8 0.1 0.52 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KLO08319.1 - 0.019 15.0 0.0 8.5 6.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Torsin PF06309.11 KLO08319.1 - 0.021 14.9 0.0 8.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Torsin Rad17 PF03215.15 KLO08319.1 - 0.023 14.6 0.0 0.74 9.7 0.0 2.9 2 0 0 2 2 2 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KLO08319.1 - 0.025 14.7 0.0 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain ADK PF00406.22 KLO08319.1 - 0.028 14.5 0.4 5.2 7.2 0.0 2.9 3 0 0 3 3 2 0 Adenylate kinase Mg_chelatase PF01078.21 KLO08319.1 - 0.03 13.7 0.0 6.7 6.0 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KLO08319.1 - 0.031 13.8 0.0 0.41 10.1 0.0 2.5 3 0 0 3 3 2 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KLO08319.1 - 0.032 14.0 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 KLO08319.1 - 0.042 13.6 0.0 5.7 6.6 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein TniB PF05621.11 KLO08319.1 - 0.048 13.1 0.2 7.5 5.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein RuvB_N PF05496.12 KLO08319.1 - 0.054 13.2 0.0 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KLO08319.1 - 0.06 13.1 0.0 0.64 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KLO08319.1 - 0.068 13.1 0.0 0.72 9.8 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 KLO08319.1 - 0.089 12.8 0.0 6.3 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 KLO08319.1 - 0.12 11.7 0.0 16 4.8 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family MeaB PF03308.16 KLO08319.1 - 0.2 10.6 0.0 11 4.9 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 KLO08319.1 - 0.2 11.0 0.0 32 3.8 0.0 3.8 5 0 0 5 5 5 0 KaiC zf-C2H2 PF00096.26 KLO08320.1 - 6.9e-09 35.7 5.6 0.0033 17.8 0.7 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO08320.1 - 2.2e-06 28.0 6.6 0.14 13.0 0.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KLO08320.1 - 0.00022 21.5 13.1 0.033 14.6 0.5 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 KLO08320.1 - 0.0037 17.0 0.3 0.0037 17.0 0.3 2.9 3 0 0 3 3 3 1 C2H2-type zinc-finger domain DUF2089 PF09862.9 KLO08320.1 - 0.083 12.9 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) DBD_Tnp_Mut PF03108.15 KLO08320.1 - 0.094 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 MuDR family transposase zf-BED PF02892.15 KLO08320.1 - 0.098 12.7 7.5 0.78 9.8 1.7 3.0 3 0 0 3 3 3 0 BED zinc finger FOXP-CC PF16159.5 KLO08320.1 - 0.35 11.5 2.4 3.3 8.4 0.3 2.6 2 1 1 3 3 3 0 FOXP coiled-coil domain IBR PF01485.21 KLO08320.1 - 7.9 6.8 8.6 2.5 8.4 1.6 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF4064 PF13273.6 KLO08322.1 - 0.83 10.0 4.4 13 6.1 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2628 PF10947.8 KLO08322.1 - 9.6 6.6 7.9 1.8 8.9 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) UQ_con PF00179.26 KLO08323.1 - 2.9e-11 43.2 0.0 5.3e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 KLO08324.1 - 7.7e-10 38.6 0.0 1.9e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme F-box PF00646.33 KLO08324.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain Sortilin-Vps10 PF15902.5 KLO08325.1 - 5.1e-14 51.9 0.2 0.00035 19.5 0.0 5.0 4 2 1 5 5 5 4 Sortilin, neurotensin receptor 3, BNR PF02012.20 KLO08325.1 - 1.1e-06 27.7 31.3 1.2 9.4 0.5 8.3 8 0 0 8 8 8 5 BNR/Asp-box repeat PSII_BNR PF14870.6 KLO08325.1 - 0.00077 18.8 6.8 0.055 12.7 0.0 5.0 5 1 2 7 7 7 2 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.6 KLO08325.1 - 0.021 14.2 6.7 4.7 6.4 0.6 5.4 3 2 2 5 5 5 0 BNR repeat-like domain UQ_con PF00179.26 KLO08326.1 - 1.2e-07 31.4 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box PF00646.33 KLO08326.1 - 0.00082 19.2 0.0 0.0021 17.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain zf-C3H1 PF10650.9 KLO08327.1 - 1.5e-06 27.8 2.2 2.5e-06 27.1 2.2 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain LysR_substrate PF03466.20 KLO08328.1 - 0.095 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain Topo-VIb_trans PF09239.11 KLO08328.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer HLH PF00010.26 KLO08329.1 - 7.7e-07 29.0 0.0 1.7e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Polysacc_deac_1 PF01522.21 KLO08331.1 - 2.6e-31 108.1 0.0 4.3e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KLO08331.1 - 0.0036 16.5 0.0 0.0052 16.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 HTH_23 PF13384.6 KLO08331.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain DUF2316 PF10078.9 KLO08331.1 - 0.19 12.0 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Collagen PF01391.18 KLO08333.1 - 1.4e-07 31.1 17.7 2e-07 30.6 17.7 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Caskin1-CID PF16600.5 KLO08334.1 - 0.049 14.2 4.3 0.079 13.6 4.3 1.5 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain TRP PF06011.12 KLO08335.1 - 0.15 10.7 0.0 0.17 10.6 0.0 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel RecG_wedge PF17191.4 KLO08345.1 - 0.03 14.0 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 RecG wedge domain PsaX PF08078.12 KLO08346.1 - 0.12 12.4 1.1 0.19 11.7 1.1 1.3 1 0 0 1 1 1 0 PsaX family F-box-like PF12937.7 KLO08347.1 - 9.5e-08 31.8 0.7 6.4e-07 29.2 0.6 2.4 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO08348.1 - 1.2e-08 34.7 0.2 5.3e-08 32.6 0.1 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO08348.1 - 0.11 13.0 0.7 4.8 7.7 0.0 2.9 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO08349.1 - 4.2e-08 33.0 2.1 1.1e-07 31.6 2.1 1.8 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08351.1 - 7.3e-07 29.0 0.2 7.3e-07 29.0 0.2 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO08351.1 - 0.21 11.5 2.7 18 5.4 0.1 3.3 3 0 0 3 3 3 0 F-box domain FtsJ PF01728.19 KLO08352.1 - 5.1e-46 157.0 0.0 6.1e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase F-box-like PF12937.7 KLO08353.1 - 2.2e-09 37.0 1.8 4.1e-09 36.2 0.0 2.3 2 2 0 2 2 2 1 F-box-like F-box_5 PF18511.1 KLO08353.1 - 0.046 13.3 1.5 0.17 11.5 0.2 2.3 2 0 0 2 2 2 0 F-box F-box PF00646.33 KLO08353.1 - 0.39 10.7 3.4 18 5.3 0.0 3.2 3 0 0 3 3 3 0 F-box domain CVNH PF08881.10 KLO08355.1 - 1.6e-20 73.7 1.6 2.3e-20 73.2 1.6 1.2 1 0 0 1 1 1 1 CVNH domain DUF916 PF06030.12 KLO08355.1 - 0.026 14.6 1.5 0.045 13.8 0.6 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) RNase_H PF00075.24 KLO08356.1 - 0.17 12.1 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 RNase H FUSC-like PF12805.7 KLO08357.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS CVNH PF08881.10 KLO08358.1 - 6.6e-18 65.3 1.9 2.8e-17 63.2 1.7 1.9 1 1 0 1 1 1 1 CVNH domain DUF916 PF06030.12 KLO08358.1 - 0.08 13.0 2.6 3.7 7.6 0.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) Tyosinase_C PF18132.1 KLO08358.1 - 0.15 12.8 0.5 4.4 8.0 0.0 2.1 1 1 1 2 2 2 0 Tyosinase C-terminal domain CVNH PF08881.10 KLO08359.1 - 1e-18 67.9 2.4 1.5e-18 67.4 2.4 1.2 1 0 0 1 1 1 1 CVNH domain Big_1 PF02369.16 KLO08359.1 - 0.48 10.5 6.8 1 9.4 0.0 3.6 3 1 1 4 4 4 0 Bacterial Ig-like domain (group 1) Pkinase PF00069.25 KLO08360.1 - 8.1e-65 218.8 0.0 2.3e-63 214.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08360.1 - 1.3e-35 122.9 0.0 5.8e-35 120.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KLO08360.1 - 1.1e-16 60.3 0.2 1.9e-16 59.6 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 KLO08360.1 - 3.2e-06 26.7 0.1 5.3e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KLO08360.1 - 1.7e-05 24.3 0.0 3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO08360.1 - 0.0001 22.4 0.0 0.0056 16.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KLO08360.1 - 0.00028 20.0 0.2 0.00045 19.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain WaaY PF06176.11 KLO08360.1 - 0.017 14.8 0.2 0.028 14.0 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.9 KLO08360.1 - 0.19 11.3 0.1 0.41 10.1 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KLO08360.1 - 0.19 11.3 0.1 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family PLAC8 PF04749.17 KLO08361.1 - 5.3e-24 85.1 7.5 6.8e-24 84.7 7.5 1.1 1 0 0 1 1 1 1 PLAC8 family Methyltransf_31 PF13847.6 KLO08362.1 - 6.6e-14 52.0 0.0 3.5e-13 49.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO08362.1 - 4e-13 49.5 0.0 6e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO08362.1 - 1.3e-11 45.1 0.0 2.5e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO08362.1 - 6.2e-11 42.8 0.0 1.4e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO08362.1 - 6.2e-09 36.5 0.0 1.6e-08 35.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KLO08362.1 - 3e-05 23.6 0.0 7e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 KLO08362.1 - 0.0064 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 KLO08362.1 - 0.04 14.0 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KLO08362.1 - 0.04 13.7 0.0 0.085 12.6 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KLO08362.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KLO08362.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 KLO08362.1 - 0.22 10.8 0.0 0.76 9.1 0.0 1.8 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G PhyH PF05721.13 KLO08364.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) ThrE PF06738.12 KLO08366.1 - 5.5e-40 137.2 0.7 5.5e-40 137.2 0.7 2.5 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KLO08366.1 - 2e-05 24.7 23.5 0.0008 19.6 5.3 2.6 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Ribosomal_L7Ae PF01248.26 KLO08367.1 - 2e-25 88.3 0.1 2.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KLO08367.1 - 0.00019 21.2 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain ThrE PF06738.12 KLO08368.1 - 3.1e-40 138.1 17.0 2.4e-39 135.2 5.2 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KLO08368.1 - 4.5e-06 26.8 30.5 6.9e-06 26.2 10.7 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Pkinase_Tyr PF07714.17 KLO08369.1 - 5.7e-67 225.7 0.0 6.4e-41 140.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KLO08369.1 - 9.9e-60 202.1 0.0 3.1e-34 118.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KLO08369.1 - 1.1e-05 24.9 0.0 0.15 11.3 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KLO08369.1 - 2.7e-05 23.6 0.1 0.063 12.6 0.1 2.7 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO08369.1 - 6.2e-05 22.7 0.1 0.078 12.6 0.0 2.3 2 0 0 2 2 2 2 RIO1 family APH PF01636.23 KLO08369.1 - 7.3e-05 22.8 0.2 0.27 11.1 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KLO08369.1 - 0.00066 18.8 0.0 0.58 9.2 0.0 2.2 2 0 0 2 2 2 2 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 KLO08369.1 - 0.11 12.1 0.0 5.6 6.4 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL MFS_1 PF07690.16 KLO08370.1 - 1e-33 116.8 26.5 1e-33 116.8 26.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KLO08370.1 - 8.4e-06 24.5 3.8 1.9e-05 23.3 3.8 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KLO08371.1 - 7.2e-26 90.9 15.1 7.2e-26 90.9 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ecm33 PF12454.8 KLO08372.1 - 0.3 11.3 3.3 0.73 10.0 3.3 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Fungal_trans PF04082.18 KLO08374.1 - 2e-10 40.2 0.1 1e-09 37.8 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO08374.1 - 0.011 15.9 3.7 0.027 14.6 3.7 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.18 KLO08374.1 - 0.014 15.6 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF3450 PF11932.8 KLO08374.1 - 0.12 11.6 0.3 0.22 10.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) LPP PF04728.13 KLO08374.1 - 0.2 12.1 0.5 0.42 11.0 0.5 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper PIF2 PF04631.12 KLO08375.1 - 0.072 11.9 0.0 0.09 11.6 0.0 1.1 1 0 0 1 1 1 0 Per os infectivity factor 2 BatA PF07584.11 KLO08375.1 - 0.084 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal NmrA PF05368.13 KLO08377.1 - 3.3e-30 105.4 0.0 5.2e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO08377.1 - 4.6e-07 29.9 0.0 7.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Axin_b-cat_bind PF08833.10 KLO08378.1 - 3.6 7.8 9.3 0.36 11.0 0.8 3.3 3 0 0 3 3 3 0 Axin beta-catenin binding domain Nucleo_P87 PF07267.11 KLO08379.1 - 3.9 6.2 8.9 4.6 6.0 8.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MFS_1 PF07690.16 KLO08380.1 - 5.2e-20 71.7 55.0 7e-18 64.7 43.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SurE PF01975.17 KLO08382.1 - 1.1e-36 126.4 1.2 1.6e-36 125.9 1.2 1.3 1 0 0 1 1 1 1 Survival protein SurE Questin_oxidase PF14027.6 KLO08383.1 - 3.9e-85 286.4 0.0 4.7e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like BTB PF00651.31 KLO08384.1 - 0.00042 20.5 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain CamS PF07537.11 KLO08384.1 - 0.23 10.6 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor BTB PF00651.31 KLO08385.1 - 3.6e-05 23.9 0.1 0.00013 22.2 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO08386.1 - 9.6e-05 22.6 0.1 0.00021 21.5 0.1 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO08387.1 - 2.5e-05 24.5 0.1 8.5e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO08388.1 - 2.2e-05 24.6 0.4 0.00012 22.3 0.1 2.3 2 1 0 2 2 2 1 BTB/POZ domain IpaB_EvcA PF03278.13 KLO08388.1 - 0.15 11.8 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 IpaB/EvcA family BTB PF00651.31 KLO08389.1 - 0.00011 22.4 0.0 0.00058 20.1 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain DUF3716 PF12511.8 KLO08389.1 - 0.22 11.6 3.1 0.39 10.8 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) BTB PF00651.31 KLO08390.1 - 8.1e-05 22.8 0.1 0.00082 19.6 0.0 2.6 3 1 0 3 3 3 1 BTB/POZ domain Nbs1_C PF08599.10 KLO08390.1 - 0.029 14.5 0.0 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 BTB PF00651.31 KLO08391.1 - 2.9e-06 27.5 0.0 1.3e-05 25.4 0.0 2.0 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO08392.1 - 1.6e-06 28.3 0.1 4.9e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO08393.1 - 3.1e-05 24.2 0.0 8.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO08394.1 - 2.3e-05 24.6 0.0 0.0013 19.0 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain GIT_CC PF16559.5 KLO08395.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Plavaka PF18759.1 KLO08398.1 - 2.7e-118 394.9 0.9 3.5e-118 394.5 0.9 1.1 1 0 0 1 1 1 1 Plavaka transposase IFT20 PF14931.6 KLO08399.1 - 4.6 7.5 8.7 13 6.0 8.7 1.8 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 BTB PF00651.31 KLO08400.1 - 1.6e-05 25.1 0.3 4.5e-05 23.6 0.3 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO08401.1 - 2.9e-06 27.5 1.5 9.9e-06 25.8 0.7 2.3 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO08402.1 - 1.1e-06 28.8 1.2 2e-05 24.8 0.9 2.7 2 1 0 2 2 2 1 BTB/POZ domain Redoxin PF08534.10 KLO08402.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Redoxin BTB PF00651.31 KLO08403.1 - 3.8e-06 27.1 0.6 1.2e-05 25.5 0.1 2.0 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO08404.1 - 1.4e-05 25.3 0.2 6.5e-05 23.1 0.2 2.0 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO08405.1 - 9e-06 25.9 1.0 2.9e-05 24.3 0.2 2.2 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO08406.1 - 6.5e-05 23.1 0.2 0.00032 20.9 0.3 2.1 1 1 1 2 2 2 1 BTB/POZ domain ANAPC10 PF03256.16 KLO08406.1 - 0.18 11.5 0.1 0.34 10.5 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) BTB PF00651.31 KLO08407.1 - 2.3e-05 24.6 0.6 0.00053 20.2 0.6 2.5 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO08408.1 - 2e-05 24.8 0.8 0.0008 19.6 0.3 3.0 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO08409.1 - 0.0001 22.5 1.0 0.00073 19.7 0.1 2.4 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO08410.1 - 4.5e-06 26.9 0.1 1.7e-05 25.0 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO08411.1 - 2.6e-06 27.6 1.8 9e-06 25.9 0.8 2.4 2 1 0 2 2 2 1 BTB/POZ domain Ric8 PF10165.9 KLO08412.1 - 3.7e-112 375.7 0.0 5.2e-112 375.2 0.0 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn UvrD_C_2 PF13538.6 KLO08413.1 - 0.002 17.9 0.2 0.011 15.5 0.2 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain CD34_antigen PF06365.12 KLO08416.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family p450 PF00067.22 KLO08417.1 - 2e-200 666.4 0.0 6.8e-66 222.9 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 DUF4791 PF16039.5 KLO08417.1 - 0.00021 20.9 0.2 0.089 12.3 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4791) Tape_meas_lam_C PF09718.10 KLO08417.1 - 0.0047 17.0 0.3 2.4 8.4 0.0 3.5 3 0 0 3 3 3 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) p450 PF00067.22 KLO08418.1 - 2.5e-62 211.1 0.0 4.4e-62 210.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 TraS PF10624.9 KLO08420.1 - 0.071 13.0 2.7 0.13 12.1 2.7 1.5 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS RTA1 PF04479.13 KLO08421.1 - 5e-58 196.1 3.0 8.6e-58 195.4 3.0 1.4 1 0 0 1 1 1 1 RTA1 like protein HMG_box PF00505.19 KLO08422.1 - 1.3e-14 54.3 0.2 1.7e-14 53.9 0.2 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO08422.1 - 2.3e-06 28.1 0.1 4e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KLO08427.1 - 4e-11 43.2 4.9 1.1e-07 32.2 3.1 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO08427.1 - 9.8e-08 32.5 6.1 3.1e-06 27.7 3.5 2.2 2 0 0 2 2 2 2 HMG-box domain Ntox11 PF15521.6 KLO08427.1 - 0.053 13.1 0.1 0.063 12.9 0.1 1.2 1 0 0 1 1 1 0 Novel toxin 11 Methyltransf_25 PF13649.6 KLO08430.1 - 4.7e-09 36.8 0.0 9.2e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO08430.1 - 5.3e-08 32.9 0.0 7.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO08430.1 - 1.1e-05 24.9 0.0 5.3e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KLO08430.1 - 9.2e-05 23.0 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO08430.1 - 0.02 14.7 0.0 0.051 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KLO08431.1 - 5e-11 43.1 0.0 4.6e-10 40.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO08431.1 - 5e-10 39.9 0.0 8.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO08431.1 - 7.1e-09 35.6 0.0 4.3e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO08431.1 - 2.6e-07 30.2 0.0 1.1e-06 28.1 0.0 1.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KLO08431.1 - 2.9e-07 30.5 0.0 4.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO08431.1 - 0.0014 19.4 0.0 0.0041 17.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KLO08431.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase PrmA PF06325.13 KLO08431.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KLO08431.1 - 0.039 13.7 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_23 PF13489.6 KLO08432.1 - 6e-13 49.0 0.0 8.9e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO08432.1 - 8.8e-12 45.6 0.0 2.8e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO08432.1 - 3.8e-10 40.3 0.0 7.3e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO08432.1 - 3e-09 36.8 0.0 7e-08 32.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO08432.1 - 2.6e-08 33.5 0.0 1e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KLO08432.1 - 6.6e-05 23.6 0.0 0.00023 21.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KLO08432.1 - 0.0011 18.8 0.0 0.0062 16.4 0.0 1.9 2 0 0 2 2 2 1 Hypothetical methyltransferase YadA_anchor PF03895.15 KLO08432.1 - 0.097 12.8 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 YadA-like membrane anchor domain FtsJ PF01728.19 KLO08432.1 - 0.13 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase LSM PF01423.22 KLO08433.1 - 1.2e-19 69.8 0.2 1.4e-19 69.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF4050 PF13259.6 KLO08435.1 - 0.0075 16.6 0.1 0.0075 16.6 0.1 2.8 2 2 1 3 3 3 1 Protein of unknown function (DUF4050) Methyltransf_25 PF13649.6 KLO08436.1 - 5.3e-11 43.1 0.0 8.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO08436.1 - 2.7e-09 37.0 0.0 5.2e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO08436.1 - 8.9e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO08436.1 - 2.7e-08 34.4 0.0 4.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO08436.1 - 1.3e-06 27.9 0.0 2.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KLO08436.1 - 2.9e-05 24.7 0.0 4.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KLO08436.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FtsJ PF01728.19 KLO08436.1 - 0.033 14.3 0.0 0.077 13.1 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 KLO08437.1 - 3.6e-11 43.6 0.0 9.2e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO08437.1 - 1.5e-09 38.3 0.0 3.3e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO08437.1 - 8.3e-09 35.4 0.0 4.3e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO08437.1 - 1.1e-08 34.7 0.0 6e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KLO08437.1 - 6.7e-07 29.3 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO08437.1 - 0.00042 21.0 0.0 0.0013 19.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KLO08437.1 - 0.0086 16.0 0.0 0.024 14.5 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_16 PF10294.9 KLO08437.1 - 0.047 13.4 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KLO08437.1 - 0.19 11.1 0.1 0.37 10.1 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) adh_short PF00106.25 KLO08438.1 - 4.2e-22 78.6 0.0 2.8e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KLO08438.1 - 2.9e-12 46.6 0.0 1.7e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO08438.1 - 1.7e-05 24.8 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KLO08438.1 - 0.0046 16.4 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KLO08438.1 - 0.011 15.1 0.0 0.03 13.8 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KLO08438.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KLO08438.1 - 0.08 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1776 PF08643.10 KLO08438.1 - 0.097 12.0 0.0 2.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.20 KLO08438.1 - 0.17 12.0 0.1 0.45 10.6 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_23 PF13489.6 KLO08441.1 - 1.3e-08 34.9 0.0 2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO08441.1 - 1.1e-07 32.4 0.0 2.6e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO08441.1 - 1.9e-06 28.4 0.0 5.6e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO08441.1 - 1.2e-05 24.8 0.0 0.00015 21.2 0.0 2.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KLO08441.1 - 0.0019 18.0 0.0 0.0083 15.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KLO08441.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_23 PF13489.6 KLO08442.1 - 1.7e-12 47.5 0.0 2.4e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO08442.1 - 3.8e-12 46.8 0.0 1.6e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO08442.1 - 4.2e-09 36.9 0.0 1.9e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO08442.1 - 1.2e-08 34.6 0.0 2.6e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KLO08442.1 - 1.7e-08 34.4 0.0 8.5e-08 32.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO08442.1 - 3e-05 24.7 0.0 0.00011 22.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KLO08442.1 - 3.9e-05 23.8 0.0 0.0065 16.6 0.0 2.2 1 1 1 2 2 2 1 FtsJ-like methyltransferase TPMT PF05724.11 KLO08442.1 - 0.0061 16.2 0.0 0.0096 15.6 0.0 1.5 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) DUF3703 PF12487.8 KLO08442.1 - 0.034 14.0 0.0 0.08 12.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3703) Methyltransf_8 PF05148.15 KLO08442.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase MTS PF05175.14 KLO08442.1 - 0.12 11.9 0.0 0.4 10.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KLO08443.1 - 1.2e-13 51.6 0.0 1.8e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO08443.1 - 1.5e-13 50.9 0.0 2.3e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO08443.1 - 9.8e-13 48.2 0.0 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO08443.1 - 8.2e-12 45.6 0.0 1.4e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO08443.1 - 6.9e-10 38.7 0.0 3.2e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KLO08443.1 - 1.2e-08 35.6 0.0 1.9e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KLO08443.1 - 0.0076 15.9 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.17 KLO08443.1 - 0.014 14.9 0.0 0.57 9.6 0.0 2.8 3 0 0 3 3 3 0 Putative methyltransferase CMAS PF02353.20 KLO08443.1 - 0.024 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 KLO08443.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Peptidase_S28 PF05577.12 KLO08444.1 - 1.7e-54 185.3 5.7 1.1e-53 182.7 5.7 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KLO08444.1 - 0.00079 19.0 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family EVE PF01878.18 KLO08445.1 - 1.3e-42 145.2 0.2 2.1e-42 144.6 0.2 1.3 1 0 0 1 1 1 1 EVE domain RRM_1 PF00076.22 KLO08447.1 - 1.7e-32 111.1 0.0 3.2e-16 58.9 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KLO08447.1 - 5.5e-05 23.2 0.0 0.00016 21.7 0.0 1.8 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 KLO08447.1 - 0.00056 19.9 0.0 0.0017 18.3 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KLO08447.1 - 0.0014 18.7 0.0 0.59 10.3 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KLO08447.1 - 0.018 14.6 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2271 PF10029.9 KLO08447.1 - 0.14 11.8 0.2 0.4 10.3 0.2 1.8 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) RRM_occluded PF16842.5 KLO08447.1 - 0.16 11.8 0.0 0.64 9.9 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif Band_7 PF01145.25 KLO08448.1 - 5.5e-26 91.6 4.2 8.3e-26 91.1 4.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family zf-C3HC4_3 PF13920.6 KLO08450.1 - 1.5e-06 27.9 13.5 2.5e-06 27.2 13.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO08450.1 - 0.00017 21.5 15.1 0.00027 20.8 15.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KLO08450.1 - 0.00019 21.7 16.3 0.0003 21.1 16.3 1.3 1 0 0 1 1 1 1 Ring finger domain ZapB PF06005.12 KLO08450.1 - 0.0002 21.7 8.6 0.046 14.2 0.7 3.0 3 0 0 3 3 2 2 Cell division protein ZapB DUF5082 PF16888.5 KLO08450.1 - 0.0015 18.8 5.9 0.12 12.6 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) DivIC PF04977.15 KLO08450.1 - 0.0016 18.2 5.5 0.32 10.8 0.1 2.5 2 0 0 2 2 2 2 Septum formation initiator zf-RING_UBOX PF13445.6 KLO08450.1 - 0.0031 17.5 10.5 0.0065 16.5 10.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KLO08450.1 - 0.0031 17.4 17.0 0.005 16.7 17.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TSC22 PF01166.18 KLO08450.1 - 0.0031 17.8 2.0 1.5 9.2 0.4 2.8 2 0 0 2 2 2 1 TSC-22/dip/bun family zf-RING_10 PF16685.5 KLO08450.1 - 0.0035 17.4 8.5 0.0068 16.5 8.5 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 NRBF2 PF08961.10 KLO08450.1 - 0.0046 16.6 3.4 0.63 9.6 0.1 2.7 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator Spc7 PF08317.11 KLO08450.1 - 0.0092 14.9 4.5 0.015 14.2 4.5 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KLO08450.1 - 0.0096 15.9 8.0 0.58 10.2 4.7 2.9 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KLO08450.1 - 0.0099 16.1 7.9 0.0099 16.1 7.9 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) LPP PF04728.13 KLO08450.1 - 0.012 16.0 0.9 6.1 7.3 0.0 3.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper PEP-utilisers_N PF05524.13 KLO08450.1 - 0.014 15.5 1.3 3 8.0 0.1 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1192 PF06698.11 KLO08450.1 - 0.022 14.8 2.3 2.6 8.1 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) E3_UbLigase_R4 PF13764.6 KLO08450.1 - 0.032 12.4 1.0 0.043 12.0 1.0 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 AAA_13 PF13166.6 KLO08450.1 - 0.043 12.5 2.4 0.066 11.9 2.4 1.2 1 0 0 1 1 1 0 AAA domain zf-RING_4 PF14570.6 KLO08450.1 - 0.046 13.5 14.6 0.085 12.7 14.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SlyX PF04102.12 KLO08450.1 - 0.049 14.3 2.7 3.4 8.4 0.1 3.3 3 0 0 3 3 2 0 SlyX FlaC_arch PF05377.11 KLO08450.1 - 0.065 13.6 3.5 0.62 10.5 0.1 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prok-RING_4 PF14447.6 KLO08450.1 - 0.075 12.9 12.8 0.16 11.8 12.9 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1664 PF07889.12 KLO08450.1 - 0.076 13.1 2.8 0.15 12.1 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-C3HC4_2 PF13923.6 KLO08450.1 - 0.084 12.7 16.2 0.14 12.0 16.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4407 PF14362.6 KLO08450.1 - 0.12 11.7 4.6 0.23 10.8 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 KLO08450.1 - 0.12 12.4 9.9 1.9 8.5 1.8 3.0 2 1 0 3 3 2 0 FlxA-like protein KASH_CCD PF14662.6 KLO08450.1 - 0.18 11.6 11.3 0.5 10.2 0.2 2.7 2 1 1 3 3 2 0 Coiled-coil region of CCDC155 or KASH PI3K_P85_iSH2 PF16454.5 KLO08450.1 - 0.18 11.4 6.1 1.7 8.2 0.1 2.4 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain COG5 PF10392.9 KLO08450.1 - 0.27 11.4 2.6 0.64 10.2 2.6 1.6 1 1 0 1 1 1 0 Golgi transport complex subunit 5 DHHW PF14286.6 KLO08450.1 - 0.29 10.4 4.2 0.081 12.2 0.3 1.8 2 0 0 2 2 2 0 DHHW protein Trimer_CC PF08954.11 KLO08450.1 - 0.33 10.6 0.0 0.33 10.6 0.0 3.6 4 0 0 4 4 4 0 Trimerisation motif JIP_LZII PF16471.5 KLO08450.1 - 0.43 10.8 4.8 12 6.2 0.0 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Prefoldin_2 PF01920.20 KLO08450.1 - 0.45 10.5 5.6 15 5.6 3.0 2.6 2 0 0 2 2 2 0 Prefoldin subunit Sipho_Gp157 PF05565.11 KLO08450.1 - 0.48 10.4 6.0 7.8 6.5 6.0 2.3 1 1 0 1 1 1 0 Siphovirus Gp157 Cep57_MT_bd PF06657.13 KLO08450.1 - 0.71 10.4 5.8 1.2 9.7 0.3 2.9 3 0 0 3 3 2 0 Centrosome microtubule-binding domain of Cep57 ADIP PF11559.8 KLO08450.1 - 0.77 9.8 12.4 0.23 11.6 8.2 2.3 2 1 0 2 2 1 0 Afadin- and alpha -actinin-Binding KLRAQ PF10205.9 KLO08450.1 - 0.78 10.0 6.7 4.6 7.5 0.8 2.5 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF848 PF05852.11 KLO08450.1 - 0.84 9.7 6.8 1.3 9.1 0.3 2.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Cnn_1N PF07989.11 KLO08450.1 - 0.93 9.7 9.6 0.19 11.9 4.6 2.4 2 1 1 3 3 2 0 Centrosomin N-terminal motif 1 YabA PF06156.13 KLO08450.1 - 1 10.0 9.7 1.8 9.2 0.1 2.9 1 1 1 2 2 2 0 Initiation control protein YabA zf-RING_6 PF14835.6 KLO08450.1 - 1.2 9.1 6.1 2.2 8.2 6.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Spectrin PF00435.21 KLO08450.1 - 1.3 9.6 5.7 12 6.4 0.2 3.6 2 1 1 3 3 2 0 Spectrin repeat Herpes_UL6 PF01763.16 KLO08450.1 - 1.7 7.1 4.8 6.3 5.2 1.0 2.0 1 1 1 2 2 2 0 Herpesvirus UL6 like Cluap1 PF10234.9 KLO08450.1 - 1.7 8.0 8.3 0.43 9.9 0.3 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF4140 PF13600.6 KLO08450.1 - 2 8.9 7.7 3.4 8.2 0.6 2.8 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.9 KLO08450.1 - 2.2 8.6 7.7 3.7 7.8 2.2 2.8 2 0 0 2 2 2 0 Haemolysin XhlA DUF1272 PF06906.11 KLO08450.1 - 2.5 8.3 11.9 4.4 7.5 11.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4472 PF14739.6 KLO08450.1 - 4.1 8.2 9.3 0.55 11.0 1.3 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4472) bZIP_1 PF00170.21 KLO08450.1 - 4.6 7.4 14.5 1.9 8.6 0.0 3.2 3 0 0 3 3 2 0 bZIP transcription factor Macoilin PF09726.9 KLO08450.1 - 5.4 5.5 11.2 16 3.9 11.2 1.6 1 1 0 1 1 1 0 Macoilin family Ax_dynein_light PF10211.9 KLO08450.1 - 9.5 6.1 11.2 9 6.2 0.2 2.7 2 1 1 3 3 2 0 Axonemal dynein light chain RhoGEF PF00621.20 KLO08451.1 - 4.8e-31 108.4 0.0 8.4e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PI3K_P85_iSH2 PF16454.5 KLO08451.1 - 1.9 8.1 5.9 0.56 9.8 2.2 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CENP-H PF05837.12 KLO08451.1 - 8.6 6.8 10.1 8 6.9 1.2 3.3 3 0 0 3 3 3 0 Centromere protein H (CENP-H) F-box-like PF12937.7 KLO08452.1 - 1.3e-08 34.6 0.9 1.1e-07 31.6 1.4 2.3 2 1 0 2 2 2 1 F-box-like adh_short PF00106.25 KLO08455.1 - 2.2e-28 99.1 0.0 2e-25 89.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KLO08455.1 - 4.9e-17 62.3 0.0 6.8e-16 58.5 0.0 2.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KLO08455.1 - 1.9e-07 30.8 0.0 2.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KLO08455.1 - 3.9e-07 30.2 0.2 8.5e-07 29.1 0.2 1.6 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KLO08455.1 - 0.00031 20.3 0.0 0.00057 19.4 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DFP PF04127.15 KLO08455.1 - 0.011 15.5 1.7 0.043 13.6 1.0 2.3 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein ADH_zinc_N PF00107.26 KLO08455.1 - 0.033 14.2 0.1 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 KLO08455.1 - 0.034 14.0 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KLO08455.1 - 0.097 11.8 0.2 0.22 10.7 0.2 1.8 1 1 0 1 1 1 0 Male sterility protein Myb_DNA-binding PF00249.31 KLO08456.1 - 4.6e-23 81.1 11.6 8.1e-12 45.2 0.5 4.3 5 1 0 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KLO08456.1 - 1.4e-13 50.9 13.2 4.1e-07 30.1 0.2 4.3 3 2 1 4 4 4 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KLO08456.1 - 0.00013 22.0 0.0 0.0067 16.5 0.0 2.6 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 KLO08456.1 - 0.0055 17.1 2.1 0.0055 17.1 2.1 3.8 2 2 2 4 4 4 1 Myb/SANT-like DNA-binding domain SurA_N PF09312.11 KLO08456.1 - 0.079 13.0 0.6 1.2 9.3 0.0 2.8 3 0 0 3 3 3 0 SurA N-terminal domain MADF_DNA_bdg PF10545.9 KLO08456.1 - 0.24 11.7 4.3 11 6.4 0.1 3.7 2 1 2 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF2508 PF10704.9 KLO08456.1 - 0.25 11.5 2.4 14 6.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) SANT_DAMP1_like PF16282.5 KLO08456.1 - 0.61 10.3 3.3 23 5.3 0.0 3.5 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 DUF1844 PF08899.11 KLO08458.1 - 0.069 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) DUF498 PF04430.14 KLO08459.1 - 8.4e-30 103.1 0.0 1.2e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) KDZ PF18758.1 KLO08462.1 - 2.2e-44 151.7 0.7 3.9e-44 150.9 0.1 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO08462.1 - 5.3e-33 113.4 0.1 5.3e-33 113.4 0.1 2.2 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO08462.1 - 9.8e-05 22.5 0.1 9.8e-05 22.5 0.1 2.3 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KLO08462.1 - 0.0016 18.3 0.1 0.0037 17.1 0.1 1.6 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases FadR_C PF07840.12 KLO08462.1 - 0.089 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 FadR C-terminal domain Tet_JBP PF12851.7 KLO08463.1 - 2.1e-05 24.0 0.0 0.00015 21.2 0.0 1.9 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily Get5_C PF18514.1 KLO08464.1 - 0.16 11.7 0.5 2.8 7.7 0.1 2.9 3 0 0 3 3 3 0 Get5 C-terminal domain F-box-like PF12937.7 KLO08466.1 - 1.1e-07 31.6 0.0 2.6e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08467.1 - 7.8e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO08467.1 - 0.078 12.9 1.8 1.5 8.8 1.8 2.6 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO08468.1 - 1.1e-07 31.7 0.0 2.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO08468.1 - 0.0053 16.6 2.4 0.023 14.6 0.7 2.7 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 KLO08470.1 - 1.1e-06 28.5 0.0 2.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08471.1 - 4.2e-05 23.4 0.1 0.00031 20.6 0.0 2.4 2 0 0 2 2 2 1 F-box-like DUF1517 PF07466.11 KLO08471.1 - 0.054 13.6 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) F-box-like PF12937.7 KLO08472.1 - 3.5e-07 30.0 1.8 2.2e-06 27.5 0.2 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO08472.1 - 0.0025 17.7 0.0 0.0082 16.0 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO08474.1 - 4.8e-09 36.0 0.9 1.7e-08 34.2 0.2 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO08474.1 - 0.32 11.5 3.2 79 3.9 0.0 4.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO08475.1 - 0.065 13.1 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KLO08476.1 - 2.2e-05 24.2 1.5 0.0001 22.1 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO08477.1 - 5.1e-05 23.1 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like ArfGap PF01412.18 KLO08478.1 - 5.6e-32 110.3 0.4 5.6e-32 110.3 0.4 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf F-box-like PF12937.7 KLO08479.1 - 0.00077 19.3 2.3 0.0014 18.5 0.1 2.5 2 1 1 3 3 3 1 F-box-like F-box_4 PF15966.5 KLO08479.1 - 0.1 12.5 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 F-box AEP1 PF17049.5 KLO08479.1 - 0.1 11.7 0.0 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 ATPase expression protein 1 LRR_4 PF12799.7 KLO08479.1 - 2.5 8.7 6.1 36 5.0 0.0 4.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 KLO08483.1 - 8e-35 120.4 0.0 1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08483.1 - 2.3e-30 105.8 0.0 3.2e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO08483.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KLO08483.1 - 0.066 12.0 0.1 0.093 11.5 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KLO08484.1 - 2.9e-40 138.3 0.0 4.5e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08484.1 - 7.6e-38 130.3 0.0 1.2e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO08484.1 - 0.0002 20.3 0.0 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO08484.1 - 0.0036 17.3 0.0 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO08484.1 - 0.033 13.8 0.3 0.3 10.7 0.3 2.2 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KLO08484.1 - 0.056 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Tachystatin_A PF11406.8 KLO08484.1 - 0.12 12.4 0.2 0.48 10.5 0.2 2.1 1 0 0 1 1 1 0 Antimicrobial peptide tachystatin A Phage_GPA PF05840.13 KLO08487.1 - 0.049 12.7 0.1 0.11 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Hrs_helical PF12210.8 KLO08487.1 - 0.13 12.9 0.2 0.13 12.9 0.2 1.8 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate CCER1 PF15482.6 KLO08489.1 - 0.056 13.3 3.3 0.075 12.9 3.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Pkinase PF00069.25 KLO08492.1 - 9.3e-40 136.6 0.0 1.5e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08492.1 - 5.9e-36 124.1 0.0 8.3e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO08492.1 - 4.3e-05 23.0 0.0 7.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO08492.1 - 0.0019 17.1 0.0 0.0046 15.8 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO08492.1 - 0.03 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Epimerase_2 PF02350.19 KLO08492.1 - 0.18 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Pkinase PF00069.25 KLO08493.1 - 2.6e-34 118.8 0.0 4.5e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08493.1 - 2.7e-33 115.4 0.0 4.8e-31 108.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO08493.1 - 0.00019 20.4 0.3 0.00086 18.2 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 KLO08493.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO08493.1 - 0.093 12.1 0.0 0.54 9.6 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-MYND PF01753.18 KLO08494.1 - 2.9e-09 36.9 11.4 9.1e-09 35.3 11.4 1.9 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO08495.1 - 4.1e-09 36.4 12.5 4.1e-09 36.4 12.5 2.3 3 0 0 3 3 3 1 MYND finger Pkinase PF00069.25 KLO08496.1 - 2.1e-39 135.5 0.0 3.1e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08496.1 - 2.3e-38 131.9 0.0 3.1e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO08496.1 - 5.1e-06 26.0 0.0 8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO08496.1 - 8.6e-06 24.8 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase zf-MYND PF01753.18 KLO08497.1 - 1.1e-09 38.2 9.4 1.1e-09 38.2 9.4 2.3 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 KLO08500.1 - 2e-07 31.0 15.0 2e-07 31.0 15.0 2.2 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 KLO08501.1 - 9.1e-10 38.5 10.9 9.1e-10 38.5 10.9 1.9 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 KLO08502.1 - 9.5e-09 35.2 14.8 2.4e-08 33.9 14.8 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO08503.1 - 6.8e-09 35.7 16.5 1.6e-08 34.5 12.9 3.0 3 0 0 3 3 3 1 MYND finger Presenilin PF01080.17 KLO08504.1 - 0.0024 16.7 7.0 0.0029 16.4 7.0 1.1 1 0 0 1 1 1 1 Presenilin BUD22 PF09073.10 KLO08504.1 - 0.011 15.2 31.5 0.013 14.8 31.5 1.1 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.9 KLO08504.1 - 0.061 11.9 2.3 0.062 11.8 2.3 1.0 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 KLO08504.1 - 0.13 10.5 30.3 0.2 9.8 30.3 1.2 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 KLO08504.1 - 0.2 10.5 8.0 0.24 10.2 8.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SDA1 PF05285.12 KLO08504.1 - 0.29 10.5 37.7 0.4 10.1 37.7 1.1 1 0 0 1 1 1 0 SDA1 BAF1_ABF1 PF04684.13 KLO08504.1 - 0.38 9.8 17.5 0.51 9.3 17.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SAPS PF04499.15 KLO08504.1 - 1.2 7.8 12.2 1.4 7.6 12.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 KLO08504.1 - 1.2 7.1 10.9 1.4 6.9 10.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Smg8_Smg9 PF10220.9 KLO08504.1 - 1.6 7.0 8.0 1.8 6.8 8.0 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Tub_N PF16322.5 KLO08504.1 - 2.2 8.6 21.7 3.1 8.2 21.7 1.3 1 0 0 1 1 1 0 Tubby N-terminal Mem_trans PF03547.18 KLO08504.1 - 2.3 6.5 5.6 2.9 6.2 5.6 1.2 1 0 0 1 1 1 0 Membrane transport protein GREB1 PF15782.5 KLO08504.1 - 6.5 3.7 8.8 7.4 3.5 8.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 KLO08504.1 - 8.7 5.2 7.6 12 4.8 7.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DnaGprimase_HBD PF16730.5 KLO08505.1 - 0.1 12.7 0.0 0.33 11.0 0.1 2.0 2 0 0 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain zf-MYND PF01753.18 KLO08506.1 - 1.1e-09 38.2 11.4 2.7e-09 37.0 11.4 1.7 1 0 0 1 1 1 1 MYND finger DnaGprimase_HBD PF16730.5 KLO08506.1 - 0.049 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain PNISR PF15996.5 KLO08506.1 - 3.8 7.8 12.4 6.8 6.9 12.4 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SAPS PF04499.15 KLO08506.1 - 5.3 5.7 7.8 8.1 5.1 7.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 KLO08506.1 - 9.8 4.2 27.0 14 3.7 27.0 1.1 1 0 0 1 1 1 0 Nop14-like family MoCF_biosynth PF00994.24 KLO08507.1 - 3.6e-29 101.3 0.0 4.3e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain Rx_N PF18052.1 KLO08509.1 - 0.016 15.5 0.1 0.034 14.4 0.1 1.5 1 0 0 1 1 1 0 Rx N-terminal domain GDPD PF03009.17 KLO08510.1 - 3.1e-31 109.0 0.0 4.6e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KLO08510.1 - 1.2e-06 28.8 1.0 2e-06 28.0 0.4 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Acyltransferase PF01553.21 KLO08512.1 - 8e-34 116.2 0.0 1.1e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Nop14 PF04147.12 KLO08513.1 - 4.8e-282 938.3 18.4 5.7e-282 938.0 18.4 1.0 1 0 0 1 1 1 1 Nop14-like family Pheromone PF08015.11 KLO08515.1 - 3 9.0 0.0 3 9.0 0.0 3.5 5 0 0 5 5 5 0 Fungal mating-type pheromone Peptidase_S10 PF00450.22 KLO08516.1 - 3.2e-102 343.1 0.0 4.1e-102 342.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MtaB PF12176.8 KLO08516.1 - 0.1 11.3 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Stm1_N PF09598.10 KLO08517.1 - 2.4 9.1 11.2 5.5 7.9 11.2 1.6 1 0 0 1 1 1 0 Stm1 Mgm101p PF06420.12 KLO08518.1 - 4.4e-85 283.4 0.0 5.6e-85 283.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 GCP_N_terminal PF17681.1 KLO08519.1 - 1.3e-28 100.6 0.2 2e-28 99.9 0.2 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KLO08519.1 - 3.3e-26 92.5 0.5 3.3e-26 92.5 0.5 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal VWA PF00092.28 KLO08520.1 - 1.3e-05 25.5 0.0 0.00025 21.4 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KLO08520.1 - 0.0082 16.8 0.1 0.047 14.3 0.1 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain PCI PF01399.27 KLO08521.1 - 2.1e-11 44.3 0.0 5.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain Thioredoxin_4 PF13462.6 KLO08522.1 - 4.1e-11 43.3 0.0 2.6e-10 40.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KLO08522.1 - 0.025 14.3 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 DSBA-like thioredoxin domain GatB_N PF02934.15 KLO08523.1 - 3.9e-106 354.4 0.0 7.1e-106 353.6 0.0 1.4 2 0 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KLO08523.1 - 2.1e-28 99.0 0.1 3.4e-28 98.4 0.1 1.3 1 0 0 1 1 1 1 GatB domain DPBB_1 PF03330.18 KLO08524.1 - 9.6e-07 29.0 0.1 1.7e-06 28.2 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase WD40 PF00400.32 KLO08525.1 - 1.1e-55 184.3 32.8 7.6e-07 29.7 0.1 12.6 12 1 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO08525.1 - 8.8e-28 96.4 1.0 1.5e-05 25.2 0.0 9.1 4 3 4 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KLO08525.1 - 8.3e-16 58.2 1.9 1.5e-15 57.4 1.9 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 KLO08525.1 - 5.7e-10 38.5 6.2 0.00092 18.0 0.1 5.8 5 1 1 6 6 6 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KLO08525.1 - 1.1e-06 28.2 0.0 1 8.6 0.0 5.2 5 1 1 6 6 6 2 WD40-like domain Ge1_WD40 PF16529.5 KLO08525.1 - 7.4e-06 25.1 5.5 8.6 5.2 0.1 6.5 4 2 4 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KLO08525.1 - 0.0009 18.1 6.2 0.43 9.3 0.0 4.6 2 2 0 4 4 4 1 Nup133 N terminal like ELYS-bb PF16687.5 KLO08525.1 - 0.02 13.5 0.0 1.7 7.1 0.0 2.8 3 0 0 3 3 3 0 beta-propeller of ELYS nucleoporin PALB2_WD40 PF16756.5 KLO08525.1 - 0.16 10.9 5.0 1.5 7.6 0.5 3.4 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Peptidase_M18 PF02127.15 KLO08526.1 - 1.6e-152 508.3 0.0 1.8e-152 508.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KLO08526.1 - 8.8e-06 24.9 0.0 0.001 18.1 0.2 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase DUF4755 PF15947.5 KLO08526.1 - 0.0043 17.0 0.1 0.0096 15.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4755) SKN1 PF03935.15 KLO08527.1 - 3.8e-181 602.9 4.7 5.3e-181 602.4 4.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) TFR_dimer PF04253.15 KLO08530.1 - 1.8e-24 86.1 4.4 2.3e-22 79.3 0.1 2.6 2 0 0 2 2 2 2 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KLO08530.1 - 8.9e-17 61.4 0.0 3.3e-16 59.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KLO08530.1 - 6.8e-10 38.8 0.1 1.6e-09 37.6 0.1 1.7 1 1 0 1 1 1 1 PA domain ORC2 PF04084.14 KLO08531.1 - 1.2e-82 277.5 0.0 1.5e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DEAD PF00270.29 KLO08532.1 - 1.7e-18 67.0 0.0 3.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO08532.1 - 6.3e-18 65.1 0.0 4.7e-17 62.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KLO08532.1 - 3.4e-09 37.3 1.3 3.4e-09 37.3 1.3 2.3 3 0 0 3 3 3 1 RecQ zinc-binding PBP1_TM PF14812.6 KLO08532.1 - 0.49 10.8 2.6 1.9 8.9 2.6 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DASH_Spc19 PF08287.11 KLO08533.1 - 2.2e-21 76.4 1.1 2.7e-21 76.1 1.1 1.1 1 0 0 1 1 1 1 Spc19 Peptidase_M41 PF01434.18 KLO08533.1 - 0.032 14.1 0.1 0.039 13.8 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M41 NRho PF16733.5 KLO08533.1 - 0.053 13.6 0.1 0.13 12.3 0.1 1.8 1 1 0 1 1 1 0 Rhomboid N-terminal domain SipA PF09052.10 KLO08533.1 - 0.087 12.4 0.4 0.11 12.1 0.4 1.1 1 0 0 1 1 1 0 SipA N-terminal domain PilM PF07419.12 KLO08533.1 - 0.12 12.6 0.0 0.15 12.3 0.0 1.3 1 1 0 1 1 1 0 PilM GST_N_3 PF13417.6 KLO08534.1 - 9.8e-18 64.3 0.0 2.1e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO08534.1 - 4.3e-16 59.0 0.1 1.7e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KLO08534.1 - 2.9e-12 46.7 0.2 6.9e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO08534.1 - 4.8e-08 33.1 0.1 8.5e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KLO08534.1 - 7.1e-08 32.4 0.1 1.3e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO08534.1 - 0.00017 21.7 0.2 0.00036 20.7 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KLO08534.1 - 0.0015 19.1 0.0 0.0022 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KLO08534.1 - 0.031 15.0 0.1 0.16 12.7 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain DUF3621 PF12285.8 KLO08534.1 - 0.15 12.4 0.4 0.15 12.4 0.4 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3621) DUF2407 PF10302.9 KLO08535.1 - 7.7e-17 61.8 0.1 1.3e-16 61.0 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.6 KLO08535.1 - 1.1e-16 61.3 1.7 2.5e-15 56.9 1.7 2.3 1 1 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 KLO08535.1 - 2.3e-06 27.2 0.0 3.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family VIT1 PF01988.19 KLO08535.1 - 0.07 13.0 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 VIT family Rad60-SLD_2 PF13881.6 KLO08535.1 - 0.12 12.5 0.1 0.61 10.2 0.1 2.2 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like adh_short PF00106.25 KLO08536.1 - 3e-28 98.6 1.7 4.3e-28 98.1 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO08536.1 - 2.1e-25 89.7 0.6 2.9e-25 89.2 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.15 KLO08536.1 - 0.00044 20.2 0.2 0.0029 17.5 0.1 2.0 2 0 0 2 2 2 1 YjeF-related protein N-terminus 3HCDH_N PF02737.18 KLO08536.1 - 0.02 14.8 0.4 0.04 13.8 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 KLO08536.1 - 0.14 11.6 1.2 0.21 11.1 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family Presenilin PF01080.17 KLO08537.1 - 9.1 4.9 5.1 10 4.7 5.1 1.2 1 0 0 1 1 1 0 Presenilin Kin17_mid PF10357.9 KLO08541.1 - 1.2e-49 167.4 0.5 1.2e-49 167.4 0.5 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KLO08541.1 - 0.00055 20.2 6.3 0.0014 19.0 6.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KLO08541.1 - 0.016 15.5 5.2 0.036 14.4 5.2 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KLO08541.1 - 0.026 14.9 0.6 0.026 14.9 0.6 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-CCCH PF00642.24 KLO08542.1 - 1.1e-14 53.9 29.3 2.6e-06 27.2 2.7 4.5 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KLO08542.1 - 8.1e-10 38.4 41.6 4.2e-05 23.4 4.8 5.2 4 2 0 4 4 4 2 Zinc finger domain Torus PF16131.5 KLO08542.1 - 1.2e-09 38.8 15.4 0.0034 18.1 0.6 4.4 3 1 1 4 4 4 4 Torus domain zf-CCCH_4 PF18044.1 KLO08542.1 - 2.8e-09 36.6 41.3 1.8e-05 24.4 4.0 4.7 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KLO08542.1 - 0.037 14.2 17.2 2.6 8.3 1.3 4.1 4 0 0 4 4 4 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KLO08542.1 - 0.2 12.2 33.8 0.069 13.7 2.7 4.2 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger zf-RING_2 PF13639.6 KLO08543.1 - 1.9e-12 47.3 4.4 3.9e-12 46.3 4.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KLO08543.1 - 2.1e-10 40.1 3.0 5.3e-10 38.9 3.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger PA PF02225.22 KLO08543.1 - 3.2e-09 36.7 0.0 7.2e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 KLO08543.1 - 4e-06 26.7 1.7 7.3e-06 25.9 1.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KLO08543.1 - 2.5e-05 24.0 3.9 4.6e-05 23.2 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO08543.1 - 0.00014 21.6 2.8 0.00027 20.7 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO08543.1 - 0.00018 21.3 1.7 0.00041 20.2 1.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KLO08543.1 - 0.00057 20.1 6.2 0.0019 18.4 5.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KLO08543.1 - 0.002 18.1 3.6 0.011 15.7 0.4 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KLO08543.1 - 0.022 14.8 3.3 0.075 13.1 3.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KLO08543.1 - 0.022 14.6 3.2 0.048 13.5 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_RING PF05883.11 KLO08543.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Zn_ribbon_17 PF17120.5 KLO08543.1 - 0.19 11.4 2.7 0.45 10.2 2.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KLO08543.1 - 0.87 9.8 4.1 6.1 7.1 4.1 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zinc_ribbon_16 PF17034.5 KLO08543.1 - 1.3 9.2 5.3 2.5 8.3 0.7 2.3 1 1 1 2 2 2 0 Zinc-ribbon like family Heme_oxygenase PF01126.20 KLO08544.1 - 1.3e-37 129.6 0.0 4.3e-37 127.9 0.0 1.8 1 1 0 1 1 1 1 Heme oxygenase SP2 PF03014.14 KLO08544.1 - 0.079 11.4 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Structural protein 2 CBFD_NFYB_HMF PF00808.23 KLO08547.1 - 1.1e-20 73.6 0.8 1.5e-20 73.2 0.8 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KLO08547.1 - 3.4e-13 50.1 0.1 4.5e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KLO08547.1 - 0.018 15.3 0.1 0.03 14.6 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TAF PF02969.17 KLO08547.1 - 0.098 12.8 0.2 0.16 12.2 0.2 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TAFII28 PF04719.14 KLO08547.1 - 0.11 12.5 0.0 0.2 11.8 0.0 1.4 1 1 0 1 1 1 0 hTAFII28-like protein conserved region Heme_oxygenase PF01126.20 KLO08548.1 - 1.1e-35 123.3 0.0 1.6e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase Ricin_B_lectin PF00652.22 KLO08549.1 - 0.025 14.8 0.0 0.4 10.9 0.0 2.0 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain BclA_C PF18573.1 KLO08549.1 - 0.11 12.4 2.2 0.21 11.5 2.2 1.5 1 0 0 1 1 1 0 BclA C-terminal domain Asp PF00026.23 KLO08550.1 - 2.1e-17 63.6 3.9 9.5e-15 54.8 3.9 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO08550.1 - 0.0001 22.6 1.1 0.028 14.6 0.2 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TMEM52 PF14979.6 KLO08550.1 - 0.041 13.8 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Transmembrane 52 gag-asp_proteas PF13975.6 KLO08550.1 - 0.06 13.9 0.4 1.2 9.8 0.0 3.0 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KLO08550.1 - 0.19 12.4 1.3 0.39 11.4 0.2 2.1 2 0 0 2 2 2 0 Aspartyl protease Dynactin_p62 PF05502.13 KLO08551.1 - 8.1e-68 229.3 13.2 2.3e-41 142.1 7.3 2.1 1 1 1 2 2 2 2 Dynactin p62 family zf-CHY PF05495.12 KLO08551.1 - 2.5 8.6 15.7 3.7 8.1 5.6 2.7 3 0 0 3 3 3 0 CHY zinc finger TAF PF02969.17 KLO08552.1 - 2.9e-23 81.8 0.4 5.5e-23 80.9 0.4 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 KLO08552.1 - 1.1e-14 54.5 0.0 2.4e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 KLO08552.1 - 0.012 16.0 0.7 0.022 15.1 0.7 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KLO08552.1 - 0.066 13.3 0.2 0.17 12.0 0.1 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit HEAT_EZ PF13513.6 KLO08552.1 - 0.51 10.9 3.2 11 6.6 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat RL10P_insert PF17777.1 KLO08553.1 - 1e-21 76.7 0.0 2.1e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KLO08553.1 - 3.7e-18 65.5 0.0 5.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 DUF5341 PF17276.2 KLO08553.1 - 0.14 12.3 0.2 0.24 11.5 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5341) RrnaAD PF00398.20 KLO08554.1 - 2.9e-59 200.3 0.0 3.6e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KLO08554.1 - 5.6e-07 30.2 0.0 1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO08554.1 - 0.00015 22.3 0.0 0.0003 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO08554.1 - 0.00019 21.0 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KLO08554.1 - 0.00044 20.1 0.0 0.00074 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KLO08554.1 - 0.0005 19.9 0.0 0.00078 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KLO08554.1 - 0.00062 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KLO08554.1 - 0.0011 19.7 0.0 0.0023 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KLO08554.1 - 0.003 16.9 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain NodS PF05401.11 KLO08554.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.17 KLO08554.1 - 0.011 15.4 0.1 0.027 14.1 0.1 1.7 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 KLO08554.1 - 0.039 13.7 0.0 0.091 12.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 KLO08554.1 - 0.049 13.0 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.12 KLO08554.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Cons_hypoth95 PF03602.15 KLO08554.1 - 0.16 11.6 0.1 0.98 9.0 0.0 2.1 2 1 1 3 3 3 0 Conserved hypothetical protein 95 HEAT_2 PF13646.6 KLO08555.1 - 1.5e-33 115.0 5.0 4.5e-15 55.8 0.3 3.6 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 KLO08555.1 - 4.7e-24 82.6 0.1 0.00083 19.8 0.0 7.0 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.22 KLO08555.1 - 6.3e-09 35.4 1.1 0.13 12.6 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.23 KLO08555.1 - 1.5e-06 28.1 0.0 0.0053 16.8 0.0 2.9 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KLO08555.1 - 0.0001 22.7 1.4 1.4 9.5 0.1 4.7 3 1 1 4 4 4 2 HEAT-like repeat zf-CCCH_6 PF18585.1 KLO08555.1 - 0.0063 16.4 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 TAF6_C PF07571.13 KLO08555.1 - 0.11 12.8 0.0 1.7 9.0 0.0 2.8 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain SOGA PF11365.8 KLO08557.1 - 0.013 16.6 4.2 0.066 14.4 4.2 2.3 1 0 0 1 1 1 0 Protein SOGA KASH_CCD PF14662.6 KLO08557.1 - 0.032 14.1 9.7 0.061 13.1 9.7 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4047 PF13256.6 KLO08557.1 - 0.1 12.8 5.5 1.3 9.2 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) FUSC PF04632.12 KLO08557.1 - 2.7 6.4 9.0 4.1 5.8 9.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIC PF04977.15 KLO08557.1 - 3 7.7 10.0 0.78 9.6 1.2 2.6 1 1 2 3 3 3 0 Septum formation initiator ZapB PF06005.12 KLO08557.1 - 4.8 7.7 12.3 17 5.9 3.6 2.7 1 1 1 2 2 2 0 Cell division protein ZapB DUF5127 PF17168.4 KLO08558.1 - 8.5e-51 172.9 0.1 1.4e-50 172.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO08558.1 - 7e-47 159.3 0.2 2.6e-46 157.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO08558.1 - 9.7e-34 117.2 0.2 1.7e-33 116.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO08558.1 - 0.0038 16.7 0.1 0.0088 15.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KLO08558.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain p450 PF00067.22 KLO08559.1 - 4.6e-69 233.4 0.0 5.3e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 KLO08564.1 - 1.1e-05 25.7 0.0 4.2e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KLO08564.1 - 0.00034 21.0 0.0 0.00077 19.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO08564.1 - 0.029 14.3 0.0 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Exo_endo_phos PF03372.23 KLO08568.1 - 3.8e-09 36.4 0.1 5.7e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 KLO08569.1 - 0.00012 21.6 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4100 PF13352.6 KLO08569.1 - 0.023 14.5 0.1 0.031 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) zf-RVT PF13966.6 KLO08571.1 - 5e-08 33.5 1.3 1.7e-07 31.8 1.3 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HypA PF01155.19 KLO08571.1 - 0.019 15.0 0.2 0.22 11.5 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SIR2 PF02146.17 KLO08573.1 - 1.5e-29 103.1 0.0 2e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Sir2 family SIR2 PF02146.17 KLO08574.1 - 1.2e-23 83.9 0.0 1.7e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF5127 PF17168.4 KLO08575.1 - 8e-47 159.9 0.2 8e-47 159.9 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO08575.1 - 1.7e-40 138.5 3.4 3.1e-40 137.6 3.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO08575.1 - 3.4e-36 125.2 0.1 7.3e-36 124.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) RRM_1 PF00076.22 KLO08576.1 - 1.4e-32 111.3 0.2 6.7e-16 57.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KLO08576.1 - 1.5e-10 41.0 0.1 2.1e-05 24.5 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KLO08576.1 - 0.15 12.1 0.0 20 5.3 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Glyco_hydro_85 PF03644.13 KLO08577.1 - 1.1e-86 291.0 0.0 1.4e-86 290.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 p31comet PF06581.12 KLO08578.1 - 0.0096 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Mad1 and Cdc20-bound-Mad2 binding Cwf_Cwc_15 PF04889.12 KLO08578.1 - 7.2 6.3 13.8 14 5.3 9.5 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KLO08578.1 - 8.1 4.5 12.9 0.1 10.8 5.1 1.8 2 0 0 2 2 2 0 Nop14-like family DNA_pol_phi PF04931.13 KLO08578.1 - 9.6 4.2 15.7 16 3.4 15.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi SH3_9 PF14604.6 KLO08579.1 - 5.6e-05 22.9 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KLO08579.1 - 0.0007 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KLO08579.1 - 0.043 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain PRCC PF10253.9 KLO08579.1 - 7.9 7.2 17.1 3.3 8.4 0.1 2.7 2 1 1 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting Suf PF05843.14 KLO08580.1 - 3.6e-68 230.7 13.5 1.2e-67 229.0 0.0 4.7 3 1 2 5 5 5 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KLO08580.1 - 3e-09 36.9 4.8 0.056 14.3 0.0 6.7 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KLO08580.1 - 0.00041 20.8 3.3 8 7.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KLO08580.1 - 0.33 10.0 7.1 1.9 7.5 0.3 4.4 4 1 2 6 6 6 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 KLO08580.1 - 0.37 11.5 8.3 4.6 8.1 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3915 PF13054.6 KLO08580.1 - 1.3 9.0 2.7 12 5.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) TPR_16 PF13432.6 KLO08580.1 - 2.5 8.8 14.5 0.41 11.3 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Hydrolase_6 PF13344.6 KLO08581.1 - 1.2e-13 51.0 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO08581.1 - 7.1e-11 42.0 0.0 1.7e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Dioxygenase_C PF00775.21 KLO08582.1 - 1.8e-11 43.8 0.0 3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase WD40 PF00400.32 KLO08583.1 - 1.3e-23 82.8 18.0 0.001 19.9 0.7 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KLO08583.1 - 0.05 12.6 0.1 0.64 8.9 0.1 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CHDCT2 PF08074.11 KLO08584.1 - 0.077 13.2 0.6 0.29 11.3 0.1 1.9 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Sec23_trunk PF04811.15 KLO08585.1 - 4e-44 151.0 0.0 7.1e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KLO08585.1 - 8.8e-23 80.1 1.2 1.6e-22 79.3 1.2 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KLO08585.1 - 3.7e-15 56.4 0.0 7.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KLO08585.1 - 2.2e-14 53.2 4.1 5e-14 52.1 4.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KLO08585.1 - 0.0011 18.8 0.0 0.0055 16.6 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat AAA PF00004.29 KLO08586.1 - 2.7e-46 157.2 0.0 1e-41 142.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KLO08586.1 - 1.8e-10 40.4 0.0 5.6e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KLO08586.1 - 7.6e-06 26.4 1.6 5e-05 23.7 0.3 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KLO08586.1 - 3.6e-05 23.9 0.0 9.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KLO08586.1 - 4.8e-05 23.2 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KLO08586.1 - 0.0043 17.3 0.3 0.22 11.8 0.0 2.8 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KLO08586.1 - 0.0047 16.9 0.0 0.021 14.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KLO08586.1 - 0.04 14.1 0.0 0.04 14.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KLO08586.1 - 0.044 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.25 KLO08586.1 - 0.057 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Bromodomain AAA_18 PF13238.6 KLO08586.1 - 0.061 13.9 0.0 0.061 13.9 0.0 2.3 3 0 0 3 3 1 0 AAA domain AAA_25 PF13481.6 KLO08586.1 - 0.081 12.5 0.0 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KLO08586.1 - 0.082 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KLO08586.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KLO08586.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KLO08586.1 - 0.13 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 KLO08586.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 KLO08586.1 - 0.79 9.5 0.0 0.79 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain K_channel_TID PF07941.11 KLO08586.1 - 7.9 7.0 8.8 27 5.3 8.8 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF4965 PF16335.5 KLO08587.1 - 9.6e-45 152.3 1.6 1.6e-44 151.6 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KLO08587.1 - 8.3e-42 143.5 0.6 1.2e-41 142.9 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KLO08587.1 - 1.2e-15 58.3 0.0 2.6e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Glyco_hydr_116N PF12215.8 KLO08587.1 - 0.034 13.6 0.4 0.066 12.7 0.2 1.5 2 0 0 2 2 2 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF1793 PF08760.11 KLO08588.1 - 1.1e-05 26.0 1.0 1.2e-05 25.8 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) HCMV_UL124 PF17609.2 KLO08588.1 - 0.05 13.8 0.7 0.11 12.7 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function DUF4965 PF16335.5 KLO08590.1 - 2.9e-43 147.5 1.4 4.4e-43 146.9 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KLO08590.1 - 1.7e-42 145.7 0.0 3.1e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KLO08590.1 - 1.2e-14 55.1 0.1 2.4e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF1793 PF08760.11 KLO08591.1 - 3.2e-05 24.5 0.1 4.8e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Syndecan PF01034.20 KLO08591.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Gram_pos_anchor PF00746.21 KLO08591.1 - 0.64 10.0 3.8 0.45 10.5 0.7 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Pkinase PF00069.25 KLO08592.1 - 8.1e-08 31.9 0.0 1.4e-06 27.9 0.0 2.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08592.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4426 PF14467.6 KLO08592.1 - 0.084 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4426) Kelch_1 PF01344.25 KLO08594.1 - 1.2e-27 95.2 16.4 1.1e-09 37.7 0.4 5.2 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KLO08594.1 - 1e-26 92.3 13.1 3.7e-09 36.5 0.4 5.1 4 1 1 5 5 5 5 Kelch motif Kelch_5 PF13854.6 KLO08594.1 - 2.9e-26 91.0 14.1 6.7e-08 32.4 0.2 5.4 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KLO08594.1 - 3.6e-24 84.5 20.4 7.2e-11 41.9 0.5 5.2 4 2 1 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KLO08594.1 - 1.9e-21 75.8 22.5 1.3e-09 38.1 0.1 6.3 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KLO08594.1 - 7.9e-20 70.0 17.9 1.8e-05 24.5 0.2 5.6 5 1 0 5 5 5 5 Kelch motif RAG2 PF03089.14 KLO08594.1 - 1.1e-06 27.9 1.0 0.028 13.4 0.0 4.3 3 2 1 5 5 5 3 Recombination activating protein 2 SapC PF07277.11 KLO08599.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 SapC DUF2353 PF09789.9 KLO08600.1 - 0.71 9.2 6.3 0.13 11.6 2.7 1.6 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) GHL6 PF14871.6 KLO08601.1 - 0.0084 16.3 0.0 0.32 11.1 0.0 2.4 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 THOC7 PF05615.13 KLO08601.1 - 0.049 13.9 9.1 11 6.3 0.6 4.2 4 0 0 4 4 4 0 Tho complex subunit 7 Kelch_4 PF13418.6 KLO08605.1 - 1.6e-34 117.7 8.6 3.2e-10 39.8 0.9 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KLO08605.1 - 2.8e-33 113.6 11.7 2.8e-10 40.2 0.3 6.4 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KLO08605.1 - 1.5e-31 107.7 5.5 4.8e-09 35.7 0.9 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KLO08605.1 - 8.4e-30 102.1 4.7 8e-09 35.5 0.7 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KLO08605.1 - 1.1e-29 101.9 2.6 1e-05 25.4 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KLO08605.1 - 1.5e-15 56.4 14.7 0.0092 15.9 0.5 7.1 6 2 0 6 6 6 5 Kelch motif RAG2 PF03089.14 KLO08605.1 - 7.9e-07 28.4 0.2 0.17 10.9 0.0 4.6 3 2 1 5 5 5 2 Recombination activating protein 2 Casc1 PF12366.8 KLO08607.1 - 0.17 11.4 0.6 40 3.6 0.0 2.9 3 0 0 3 3 3 0 Cancer susceptibility candidate 1 DDE_Tnp_4 PF13359.6 KLO08611.1 - 0.0013 18.5 0.1 0.0033 17.1 0.1 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 KLO08612.1 - 1.1e-08 35.0 0.0 1.2e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-bind_4 PF13837.6 KLO08613.1 - 0.014 15.7 2.2 0.016 15.6 0.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4407 PF14362.6 KLO08613.1 - 8.2 5.7 10.7 0.19 11.0 3.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) RE_AlwI PF09491.10 KLO08620.1 - 0.15 10.8 0.4 0.25 10.1 0.4 1.2 1 0 0 1 1 1 0 AlwI restriction endonuclease MULE PF10551.9 KLO08622.1 - 4.2e-13 49.5 0.0 7.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 KLO08622.1 - 0.0089 14.9 0.0 0.022 13.6 0.0 1.6 1 0 0 1 1 1 1 Transposase, Mutator family RGS PF00615.19 KLO08622.1 - 0.13 12.6 0.1 5.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Regulator of G protein signaling domain SWIM PF04434.17 KLO08623.1 - 0.0004 20.0 1.0 0.00058 19.5 0.1 1.7 2 0 0 2 2 2 1 SWIM zinc finger TerB PF05099.13 KLO08624.1 - 0.015 15.2 0.8 0.94 9.4 0.0 2.4 2 0 0 2 2 2 0 Tellurite resistance protein TerB GAS2 PF02187.17 KLO08624.1 - 0.022 14.9 0.1 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 Growth-Arrest-Specific Protein 2 Domain Tetraspanin PF00335.20 KLO08624.1 - 7.8 6.1 8.9 2.8 7.6 5.4 1.8 1 1 1 2 2 2 0 Tetraspanin family Dis3l2_C_term PF17877.1 KLO08625.1 - 0.32 11.3 1.7 1.6 9.1 0.5 2.7 2 1 0 2 2 2 0 DIS3-like exonuclease 2 C terminal GMC_oxred_N PF00732.19 KLO08626.1 - 2.5e-54 184.7 0.0 3.1e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO08626.1 - 1.1e-26 94.0 0.0 1.9e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KLO08626.1 - 3.8e-08 33.3 0.3 6.8e-05 22.6 0.1 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO08626.1 - 6.3e-06 26.3 0.3 4.6e-05 23.6 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KLO08626.1 - 0.00023 20.3 0.1 0.00034 19.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KLO08626.1 - 0.0013 17.9 0.5 0.0033 16.6 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KLO08626.1 - 0.0042 16.4 0.1 0.0087 15.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KLO08626.1 - 0.012 14.9 0.1 0.032 13.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO08626.1 - 0.013 14.2 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KLO08626.1 - 0.022 14.0 0.2 0.08 12.2 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KLO08626.1 - 0.16 12.0 0.1 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pkinase_Tyr PF07714.17 KLO08627.1 - 1.2e-28 100.2 0.0 2.2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08627.1 - 4.4e-26 91.8 0.0 7.3e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO08627.1 - 0.0075 16.2 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO08627.1 - 0.057 12.7 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KLO08628.1 - 5e-07 29.3 0.0 1.3e-05 24.7 0.0 2.3 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08628.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO08628.1 - 0.031 13.1 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KLO08630.1 - 3.8e-35 121.6 0.0 5e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08630.1 - 4.4e-30 104.8 0.0 7.2e-30 104.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO08630.1 - 2.8e-05 23.1 0.0 4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO08630.1 - 0.00021 20.7 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KLO08630.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Chitin_synth_2 PF03142.15 KLO08631.1 - 2.2e-241 802.1 0.1 3e-241 801.6 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KLO08631.1 - 2.2e-107 360.0 0.0 2.4e-106 356.6 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 KLO08631.1 - 5.2e-16 58.5 0.2 5.4e-10 39.3 0.0 3.6 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KLO08631.1 - 1.2e-14 54.8 0.0 2.7e-13 50.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DEK_C PF08766.11 KLO08631.1 - 1.6e-14 53.5 0.0 5.7e-14 51.8 0.1 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KLO08631.1 - 2.5e-13 50.4 3.0 2.5e-13 50.4 3.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KLO08631.1 - 6.3e-08 32.6 0.0 0.00024 20.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KLO08631.1 - 0.0046 16.4 0.0 0.046 13.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Pkinase PF00069.25 KLO08633.1 - 5.5e-36 124.3 0.0 1.6e-35 122.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08633.1 - 3.3e-34 118.4 0.0 9.5e-34 116.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KLO08633.1 - 0.0099 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KLO08634.1 - 4.2e-05 23.0 0.0 0.00022 20.7 0.0 2.3 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08634.1 - 0.025 13.9 0.0 0.054 12.8 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 KLO08635.1 - 0.00016 21.1 0.0 0.0008 18.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain DUF1003 PF06210.11 KLO08635.1 - 0.094 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Pkinase_Tyr PF07714.17 KLO08636.1 - 1.9e-38 132.2 0.0 6.9e-38 130.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08636.1 - 1.2e-33 116.6 0.0 4.9e-33 114.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KLO08636.1 - 0.0033 17.4 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO08636.1 - 0.075 12.6 0.0 0.5 9.9 0.0 2.2 2 1 0 2 2 2 0 RIO1 family Pkinase PF00069.25 KLO08637.1 - 7.5e-08 32.1 0.0 7.7e-06 25.5 0.0 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KLO08637.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KLO08637.1 - 0.048 13.6 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KLO08637.1 - 0.067 12.5 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KLO08638.1 - 1.8e-31 109.5 0.0 2.3e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08638.1 - 3.1e-29 102.1 0.0 5.1e-29 101.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO08638.1 - 0.00037 19.4 0.2 0.00055 18.8 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO08638.1 - 0.0012 18.3 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KLO08638.1 - 0.0052 16.3 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 KLO08638.1 - 0.12 12.2 0.9 0.45 10.4 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KLO08639.1 - 0.0001 21.7 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08639.1 - 0.0013 18.1 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Coatomer_WDAD PF04053.14 KLO08641.1 - 1.5e-149 498.8 0.0 2.5e-149 498.1 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KLO08641.1 - 4.1e-41 138.2 7.3 1.7e-08 35.0 0.0 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO08641.1 - 8e-10 38.9 0.0 0.22 11.8 0.0 6.2 4 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KLO08641.1 - 0.00068 19.6 0.0 16 5.6 0.0 4.4 3 2 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KLO08641.1 - 0.0014 17.4 1.1 0.11 11.1 0.0 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KLO08641.1 - 0.16 10.8 0.1 0.63 8.9 0.0 1.9 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 KLO08641.1 - 0.17 11.2 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Binary_toxB_2 PF17475.2 KLO08641.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 2 Abhydrolase_1 PF00561.20 KLO08642.1 - 9.3e-25 87.7 0.6 1.2e-15 57.9 0.6 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO08642.1 - 2.6e-18 67.4 0.8 2.6e-18 67.4 0.8 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO08642.1 - 2.2e-15 56.6 0.0 3.1e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KLO08642.1 - 3.1e-07 30.4 0.0 4.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.7 KLO08642.1 - 7.9e-05 22.5 0.2 0.73 9.6 0.2 2.9 2 1 0 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 KLO08642.1 - 0.00034 20.3 0.0 0.01 15.4 0.1 2.7 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KLO08642.1 - 0.019 14.4 0.0 0.5 9.8 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family DUF2048 PF09752.9 KLO08642.1 - 0.029 13.5 0.5 0.26 10.3 0.5 2.0 1 1 0 1 1 1 0 Abhydrolase domain containing 18 DUF2974 PF11187.8 KLO08642.1 - 0.042 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S28 PF05577.12 KLO08642.1 - 0.052 12.3 0.1 0.076 11.8 0.1 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Esterase_phd PF10503.9 KLO08642.1 - 0.094 12.2 0.1 0.29 10.6 0.3 1.6 2 0 0 2 2 2 0 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 KLO08642.1 - 0.11 11.4 0.1 0.22 10.4 0.1 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme SLATT_fungal PF18142.1 KLO08643.1 - 0.033 14.2 3.0 0.068 13.2 3.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Aim19 PF10315.9 KLO08644.1 - 2.4e-26 92.3 2.7 2.9e-26 92.0 2.7 1.1 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 NUDIX PF00293.28 KLO08645.1 - 1.3e-11 44.7 0.0 2.5e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 KLO08646.1 - 4.3e-19 68.9 0.0 5.5e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08646.1 - 1.8e-16 60.2 0.0 2.1e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KLO08646.1 - 0.0024 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KLO08647.1 - 0.0015 18.0 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08647.1 - 0.014 14.7 0.1 0.059 12.6 0.1 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KLO08648.1 - 2.1e-27 96.2 0.0 3e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08648.1 - 1.2e-26 93.6 0.0 3.6e-26 92.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO08648.1 - 2.8e-05 23.1 0.0 3.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KLO08648.1 - 9.1e-05 22.1 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 KLO08648.1 - 0.00038 19.9 0.1 0.00062 19.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KLO08648.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PCSK9_C1 PF18459.1 KLO08648.1 - 0.017 15.2 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain APH PF01636.23 KLO08648.1 - 0.078 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KLO08649.1 - 8.8e-46 156.3 0.0 1.3e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08649.1 - 3.3e-37 128.3 0.0 5.9e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO08649.1 - 0.01 15.8 0.3 0.078 12.9 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family APH_6_hur PF04655.14 KLO08649.1 - 0.13 11.6 1.0 12 5.2 0.0 3.3 4 0 0 4 4 4 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Pkinase_fungal PF17667.1 KLO08649.1 - 0.14 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Terpene_synth_C PF03936.16 KLO08651.1 - 0.0047 16.3 0.3 0.014 14.8 0.0 1.9 2 1 1 3 3 3 1 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.16 KLO08652.1 - 0.00014 21.3 0.3 0.00057 19.3 0.2 2.1 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain MFS_1 PF07690.16 KLO08653.1 - 7.8e-52 176.4 12.9 1.1e-51 175.9 12.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO08653.1 - 1e-15 57.6 22.7 1.8e-12 46.9 0.8 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 KLO08653.1 - 8.6e-07 27.6 10.1 9.2e-06 24.2 4.7 3.1 1 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KLO08653.1 - 0.00032 19.7 17.0 0.022 13.6 5.8 3.4 3 1 0 3 3 3 3 MFS_1 like family Cyt_c_ox_IV PF12270.8 KLO08653.1 - 3.5 7.8 10.0 0.29 11.2 0.6 2.9 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV DNA_pol_A_exo1 PF01612.20 KLO08654.1 - 2.5e-35 121.8 0.7 4.9e-35 120.8 0.7 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KLO08654.1 - 9.3e-23 80.7 1.6 4.3e-22 78.6 0.4 2.6 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 KLO08654.1 - 1e-12 47.8 0.0 2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 HRDC domain GCFC PF07842.12 KLO08657.1 - 2.4e-05 24.1 0.1 0.00014 21.5 0.0 2.2 2 1 1 3 3 3 1 GC-rich sequence DNA-binding factor-like protein DUF3020 PF11223.8 KLO08657.1 - 5.3 7.6 9.6 1.7 9.2 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3020) Tautomerase PF01361.21 KLO08658.1 - 0.22 11.5 0.0 0.62 10.0 0.0 1.7 2 0 0 2 2 2 0 Tautomerase enzyme THOC7 PF05615.13 KLO08660.1 - 0.04 14.2 6.6 0.11 12.8 0.2 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 DUF3020 PF11223.8 KLO08660.1 - 0.51 10.9 0.1 0.51 10.9 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3020) EMP24_GP25L PF01105.24 KLO08660.1 - 4 7.4 5.9 9 6.2 5.9 1.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD YabA PF06156.13 KLO08660.1 - 7.2 7.3 6.5 13 6.5 0.4 2.6 2 0 0 2 2 2 0 Initiation control protein YabA Rad60-SLD PF11976.8 KLO08661.1 - 1.4e-12 47.3 0.0 2.4e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like PBP1_TM PF14812.6 KLO08661.1 - 3.7 8.0 6.0 0.35 11.3 1.3 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HVSL PF09749.9 KLO08662.1 - 2.5e-44 151.5 0.0 3.1e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 KLO08662.1 - 0.00022 21.2 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily mit_SMPDase PF14724.6 KLO08662.1 - 0.14 10.1 0.0 0.17 9.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase WD40 PF00400.32 KLO08663.1 - 4.7e-05 24.1 0.1 0.092 13.7 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.8 KLO08663.1 - 0.018 13.7 0.0 0.27 9.8 0.0 2.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Terpene_synth_C PF03936.16 KLO08665.1 - 3.7e-09 36.3 0.0 6.6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.16 KLO08666.1 - 4.5e-06 26.2 0.2 7.3e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain FAM92 PF06730.11 KLO08666.1 - 0.017 14.6 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 FAM92 protein KorB PF08535.10 KLO08666.1 - 0.035 14.1 0.1 1.6 8.8 0.0 2.6 2 1 0 2 2 2 0 KorB domain Terpene_synth_C PF03936.16 KLO08667.1 - 8.8e-07 28.5 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain HHH_8 PF14716.6 KLO08667.1 - 0.11 12.9 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain Terpene_synth_C PF03936.16 KLO08668.1 - 7.5e-06 25.5 0.3 1.3e-05 24.7 0.3 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain YqgF PF14639.6 KLO08668.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 DEAD PF00270.29 KLO08669.1 - 4.5e-06 26.5 0.0 5.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SecA_DEAD PF07517.14 KLO08669.1 - 0.006 15.9 0.0 0.0067 15.8 0.0 1.0 1 0 0 1 1 1 1 SecA DEAD-like domain ResIII PF04851.15 KLO08669.1 - 0.0063 16.5 0.0 0.0066 16.5 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Terpene_synth_C PF03936.16 KLO08670.1 - 0.0009 18.7 0.3 0.0022 17.4 0.3 1.7 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain FAM92 PF06730.11 KLO08670.1 - 0.19 11.1 1.9 0.33 10.4 0.3 2.1 2 1 1 3 3 3 0 FAM92 protein Ribosomal_L35p PF01632.19 KLO08672.1 - 2.3e-18 66.4 5.3 2.7e-18 66.2 5.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 Ufd2P_core PF10408.9 KLO08673.1 - 1e-213 711.5 0.5 1.3e-213 711.1 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KLO08673.1 - 1.2e-28 99.1 3.3 2.6e-28 98.0 0.3 3.3 4 0 0 4 4 4 1 U-box domain Occludin_ELL PF07303.13 KLO08673.1 - 0.049 14.4 0.8 0.17 12.6 0.8 1.9 1 0 0 1 1 1 0 Occludin homology domain UPF0242 PF06785.11 KLO08673.1 - 0.11 12.6 1.3 0.14 12.3 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PufQ PF05398.11 KLO08674.1 - 0.082 13.0 0.4 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 PufQ cytochrome subunit Rhodanese PF00581.20 KLO08675.1 - 1.5e-08 35.1 0.0 1.9e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF3767 PF12597.8 KLO08676.1 - 1e-23 83.0 0.3 1.5e-23 82.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) POB3_N PF17292.2 KLO08677.1 - 1.1e-31 109.1 0.3 5.1e-29 100.5 0.1 2.5 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 KLO08677.1 - 1.9e-25 88.6 0.0 5.9e-25 87.0 0.0 1.9 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KLO08677.1 - 3.3e-23 81.9 0.0 4.6e-22 78.2 0.0 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like peroxidase PF00141.23 KLO08679.1 - 2.6e-27 96.0 0.0 1.4e-26 93.6 0.0 2.0 2 0 0 2 2 2 1 Peroxidase Peroxidase_ext PF11895.8 KLO08679.1 - 1.4e-26 92.2 2.2 3.1e-26 91.1 2.2 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region Smr PF01713.21 KLO08681.1 - 8.3e-17 61.3 0.0 1.9e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Smr domain DUF2781 PF10914.8 KLO08682.1 - 1.8e-42 145.2 3.2 2.1e-42 145.0 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Pkinase_Tyr PF07714.17 KLO08683.1 - 1.9e-43 148.6 0.0 3.1e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08683.1 - 1.1e-39 136.4 0.0 1.8e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08684.1 - 3.3e-41 141.3 0.0 4e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08684.1 - 5e-36 124.4 0.0 6.7e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO08684.1 - 6.4e-05 22.4 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO08684.1 - 0.0046 16.9 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO08684.1 - 0.078 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KLO08685.1 - 1e-43 149.5 0.0 1.4e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08685.1 - 5.6e-40 137.4 0.0 7.5e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO08685.1 - 0.00019 20.9 0.0 0.00038 19.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO08685.1 - 0.0074 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Enolase_N PF03952.16 KLO08685.1 - 0.029 14.5 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Enolase, N-terminal domain RIO1 PF01163.22 KLO08685.1 - 0.043 13.4 0.2 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KLO08685.1 - 0.07 13.0 0.1 0.11 12.4 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KLO08685.1 - 0.081 12.3 0.2 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cupin_5 PF06172.11 KLO08686.1 - 2.3e-40 138.0 0.0 2.8e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Pkinase_Tyr PF07714.17 KLO08687.1 - 4.6e-39 134.2 0.0 7.3e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08687.1 - 6.3e-35 120.8 0.0 9.1e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO08687.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KLO08687.1 - 0.03 13.1 1.0 0.036 12.8 0.1 1.5 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KLO08687.1 - 0.16 11.9 0.3 0.32 10.9 0.3 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Smr PF01713.21 KLO08688.1 - 5.5e-10 39.5 0.1 1.1e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 Smr domain Smr PF01713.21 KLO08689.1 - 2.6e-10 40.5 0.1 6.6e-10 39.2 0.1 1.7 2 0 0 2 2 2 1 Smr domain Smr PF01713.21 KLO08690.1 - 3.3e-10 40.2 0.0 6.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 KLO08690.1 - 4.5e-05 23.7 10.4 7.7e-05 23.0 10.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) DUF1357 PF07094.11 KLO08690.1 - 0.0042 17.2 0.3 0.0042 17.2 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1357) Smr PF01713.21 KLO08691.1 - 6.3e-12 45.7 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Smr domain Smr PF01713.21 KLO08692.1 - 1e-06 29.0 0.0 2.5e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Smr domain APG6_N PF17675.1 KLO08692.1 - 0.011 16.3 0.3 0.026 15.1 0.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 KLO08692.1 - 0.028 14.7 2.1 0.053 13.7 2.1 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 KLO08692.1 - 0.029 14.5 0.8 0.063 13.4 0.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 KLO08692.1 - 0.031 14.0 0.6 0.062 13.1 0.6 1.3 1 0 0 1 1 1 0 Septum formation initiator Atg14 PF10186.9 KLO08692.1 - 0.039 13.0 0.1 0.061 12.4 0.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 THOC7 PF05615.13 KLO08692.1 - 0.05 13.9 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 Cnn_1N PF07989.11 KLO08692.1 - 0.057 13.6 0.4 0.13 12.5 0.4 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 HIP1_clath_bdg PF16515.5 KLO08692.1 - 0.094 13.3 0.6 0.18 12.4 0.6 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fungal_TACC PF12709.7 KLO08692.1 - 0.12 12.8 0.2 0.3 11.5 0.2 1.6 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Seadorna_VP6 PF07407.11 KLO08692.1 - 0.15 11.0 0.1 0.25 10.2 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP6 protein MctB PF11382.8 KLO08692.1 - 0.15 11.7 0.5 0.25 11.0 0.5 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Pox_A_type_inc PF04508.12 KLO08692.1 - 0.18 11.7 1.2 0.28 11.1 0.1 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4140 PF13600.6 KLO08692.1 - 0.19 12.2 0.7 0.42 11.1 0.7 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF5320 PF17253.2 KLO08692.1 - 0.2 12.8 0.2 0.4 11.8 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) FXR_C1 PF16096.5 KLO08693.1 - 7.4 6.8 9.4 2.1 8.6 3.9 2.6 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 DRMBL PF07522.14 KLO08694.1 - 3.1e-28 98.2 0.0 5.6e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KLO08694.1 - 9.2e-07 28.6 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KLO08694.1 - 0.0099 15.9 0.1 0.029 14.4 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF1993 PF09351.10 KLO08695.1 - 0.016 15.4 0.2 0.022 14.9 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) RNA_pol_I_A49 PF06870.12 KLO08696.1 - 0.0076 15.2 0.5 0.011 14.6 0.5 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Mg296 PF09644.10 KLO08696.1 - 0.067 13.3 0.3 0.12 12.5 0.3 1.4 1 0 0 1 1 1 0 Mg296 protein GAS PF13851.6 KLO08696.1 - 0.12 11.8 3.1 5.7 6.2 0.1 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding RVT_N PF13655.6 KLO08696.1 - 0.13 12.5 0.1 0.37 11.1 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain of reverse transcriptase MCPsignal PF00015.21 KLO08696.1 - 0.14 12.0 1.7 11 5.8 0.0 2.8 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Fib_alpha PF08702.10 KLO08696.1 - 0.66 10.2 4.5 4.2 7.5 0.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Focal_AT PF03623.13 KLO08697.1 - 0.044 13.8 1.9 0.29 11.1 0.6 2.7 2 1 0 2 2 2 0 Focal adhesion targeting region THP2 PF09432.10 KLO08697.1 - 0.07 13.2 0.7 0.53 10.4 0.1 2.5 3 0 0 3 3 3 0 Tho complex subunit THP2 DUF4363 PF14276.6 KLO08697.1 - 0.29 11.3 1.4 6.7 6.9 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) SUZ PF12752.7 KLO08698.1 - 5.3e-11 43.1 3.8 5.3e-11 43.1 3.8 6.1 7 1 0 7 7 7 1 SUZ domain R3H PF01424.22 KLO08698.1 - 0.00028 20.8 0.0 0.00067 19.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain Aa_trans PF01490.18 KLO08699.1 - 9.5e-86 288.0 23.7 1.1e-85 287.9 23.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KLO08699.1 - 2.9e-05 23.3 15.5 2.9e-05 23.3 15.5 2.4 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Ycf9 PF01737.17 KLO08699.1 - 1.6 8.6 8.6 0.63 9.9 2.7 2.8 2 0 0 2 2 2 0 YCF9 zf-CRD PF17979.1 KLO08703.1 - 0.0072 16.4 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 2 Cysteine rich domain with multizinc binding regions Ribosomal_S4e PF00900.20 KLO08704.1 - 1.3e-24 85.9 0.0 2.7e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KLO08704.1 - 1.7e-23 82.0 0.1 2.8e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus KOW PF00467.29 KLO08704.1 - 2e-07 30.7 1.5 4.9e-07 29.5 1.5 1.7 1 0 0 1 1 1 1 KOW motif Sipho_tail PF05709.11 KLO08704.1 - 0.01 15.3 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 Phage tail protein Kelch_4 PF13418.6 KLO08704.1 - 0.13 12.3 0.1 8.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain F-box-like PF12937.7 KLO08706.1 - 1.7e-09 37.4 0.6 8.9e-09 35.1 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO08707.1 - 1.9e-11 43.7 2.8 1.1e-09 38.0 2.6 3.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO08707.1 - 0.066 13.1 6.8 0.035 14.0 2.6 2.8 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO08708.1 - 4.2e-12 45.8 6.0 5.9e-11 42.1 3.8 2.9 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO08708.1 - 0.00046 20.0 3.3 1.8 8.5 0.2 3.4 3 0 0 3 3 3 3 F-box domain F-box-like PF12937.7 KLO08710.1 - 5.5e-07 29.4 0.3 5.5e-07 29.4 0.3 3.0 4 0 0 4 4 4 1 F-box-like LRR_4 PF12799.7 KLO08710.1 - 0.14 12.6 1.6 27 5.3 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO08711.1 - 1.1e-11 44.4 1.9 4.5e-11 42.5 0.5 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO08711.1 - 0.0028 17.5 3.8 0.046 13.6 3.8 2.5 1 1 0 1 1 1 1 F-box domain DUF2172 PF09940.9 KLO08712.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) F-box-like PF12937.7 KLO08714.1 - 1.4e-06 28.1 0.3 3.8e-06 26.7 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO08719.1 - 6.9e-09 35.5 0.9 1.3e-07 31.4 0.8 2.6 2 0 0 2 2 2 1 F-box-like PyrBI_leader PF08052.11 KLO08719.1 - 0.39 10.7 2.4 1.4 8.9 0.4 2.6 2 0 0 2 2 2 0 PyrBI operon leader peptide F-box-like PF12937.7 KLO08720.1 - 3.2e-13 49.3 1.3 5.3e-12 45.4 0.5 3.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO08720.1 - 8e-05 22.4 3.3 0.0039 17.0 1.3 2.8 2 0 0 2 2 2 2 F-box domain PyrBI_leader PF08052.11 KLO08720.1 - 0.041 13.8 0.3 2.1 8.4 0.0 2.9 2 0 0 2 2 2 0 PyrBI operon leader peptide F-box-like PF12937.7 KLO08722.1 - 1.2e-10 41.1 0.5 5.4e-10 39.0 0.5 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO08722.1 - 0.017 15.0 7.8 0.1 12.5 5.4 3.1 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO08723.1 - 1.2e-10 41.1 0.4 1.2e-10 41.1 0.4 2.9 3 0 0 3 3 3 1 F-box-like PyrBI_leader PF08052.11 KLO08723.1 - 0.14 12.1 0.2 5.9 6.9 0.0 2.9 2 0 0 2 2 2 0 PyrBI operon leader peptide F-box-like PF12937.7 KLO08725.1 - 5.5e-10 39.0 0.9 5.5e-10 39.0 0.9 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO08725.1 - 0.075 12.9 4.9 0.11 12.4 2.0 2.6 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO08726.1 - 1.1e-10 41.3 1.3 3.7e-10 39.5 1.3 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO08726.1 - 0.023 14.6 1.1 0.68 9.9 0.1 2.6 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO08728.1 - 1.1e-10 41.2 0.0 3.9e-08 33.1 0.9 3.2 2 1 0 2 2 2 2 F-box-like F-box PF00646.33 KLO08728.1 - 0.54 10.2 11.4 26 4.8 8.3 3.2 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO08729.1 - 8.7e-13 48.0 2.2 2.2e-12 46.7 1.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO08729.1 - 0.00065 19.5 1.5 0.88 9.5 0.0 3.2 3 0 0 3 3 3 2 F-box domain AAA_2 PF07724.14 KLO08732.1 - 1.8e-36 125.8 0.0 3.7e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_5 PF13857.6 KLO08732.1 - 1.7e-11 44.1 0.0 3e-05 24.2 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KLO08732.1 - 1.7e-11 43.3 0.5 0.0017 18.6 0.0 5.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KLO08732.1 - 2.3e-10 40.9 0.0 8.2e-05 23.1 0.0 4.1 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) AAA_5 PF07728.14 KLO08732.1 - 4.5e-09 36.4 0.0 2e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Ank PF00023.30 KLO08732.1 - 1e-08 35.2 1.1 0.00011 22.5 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KLO08732.1 - 1.4e-08 35.1 0.2 0.042 14.4 0.0 4.9 4 1 0 4 4 4 2 Ankyrin repeats (many copies) AAA PF00004.29 KLO08732.1 - 1.3e-05 25.6 0.0 3.4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KLO08732.1 - 2.6e-05 24.2 0.0 5.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 KLO08732.1 - 0.00026 20.8 0.0 0.00062 19.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Torsin PF06309.11 KLO08732.1 - 0.0023 18.0 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 Torsin AAA_16 PF13191.6 KLO08732.1 - 0.019 15.3 0.1 0.24 11.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KLO08732.1 - 0.082 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KLO08732.1 - 0.15 12.4 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_2 PF07724.14 KLO08734.1 - 5.4e-24 85.2 1.0 4.4e-23 82.3 1.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.7 KLO08734.1 - 4.1e-12 46.5 0.0 8.8e-05 23.0 0.0 4.5 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 KLO08734.1 - 5.6e-12 45.5 0.2 0.00042 20.7 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KLO08734.1 - 9.2e-12 44.1 0.5 0.13 12.9 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KLO08734.1 - 2.5e-10 40.7 0.5 0.004 17.7 0.0 4.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KLO08734.1 - 4.6e-08 33.2 0.0 0.023 15.0 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) ClpB_D2-small PF10431.9 KLO08734.1 - 1e-06 28.7 0.1 2.2e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KLO08734.1 - 2.6e-06 27.5 0.1 1.5e-05 25.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KLO08734.1 - 1.8e-05 25.2 0.0 6.1e-05 23.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KLO08734.1 - 0.00011 22.0 0.0 0.00028 20.6 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KLO08734.1 - 0.0097 16.3 0.2 0.38 11.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Torsin PF06309.11 KLO08734.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Torsin HTH_21 PF13276.6 KLO08734.1 - 0.017 15.2 0.2 0.044 13.9 0.2 1.6 1 0 0 1 1 1 0 HTH-like domain SH3-WW_linker PF16618.5 KLO08734.1 - 0.055 13.9 2.6 0.13 12.7 2.6 1.5 1 0 0 1 1 1 0 Linker region between SH3 and WW domains on ARHGAP12 Baculo_LEF-11 PF06385.12 KLO08734.1 - 0.074 13.6 0.0 0.43 11.1 0.0 2.3 2 0 0 2 2 2 0 Baculovirus LEF-11 protein Zeta_toxin PF06414.12 KLO08734.1 - 0.075 12.3 0.1 0.57 9.4 0.0 2.4 2 1 1 3 3 3 0 Zeta toxin PEPCK_ATP PF01293.20 KLO08734.1 - 0.098 11.3 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase RNA_helicase PF00910.22 KLO08734.1 - 0.15 12.5 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase GMC_oxred_N PF00732.19 KLO08735.1 - 2e-65 221.1 0.0 2.6e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO08735.1 - 1.5e-34 119.6 0.0 2.7e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KLO08735.1 - 3.2e-05 24.1 0.1 0.00016 21.9 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO08735.1 - 0.00013 21.7 0.9 0.0028 17.3 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO08735.1 - 0.00023 20.4 0.6 0.001 18.2 0.6 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KLO08735.1 - 0.00034 19.8 0.3 0.0005 19.2 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KLO08735.1 - 0.00096 18.5 0.2 0.0022 17.3 0.2 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KLO08735.1 - 0.014 14.6 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO08735.1 - 0.018 13.7 0.1 0.036 12.8 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KLO08735.1 - 0.11 11.7 0.4 1.6 7.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BTB PF00651.31 KLO08736.1 - 7.6e-07 29.4 0.1 3.9e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 BTB/POZ domain OAR PF03826.17 KLO08736.1 - 0.0073 16.1 0.2 0.022 14.6 0.2 1.9 1 0 0 1 1 1 1 OAR domain DUF3560 PF12083.8 KLO08736.1 - 0.089 12.9 0.2 0.25 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) DUF3176 PF11374.8 KLO08737.1 - 0.0084 16.3 3.8 0.012 15.8 2.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) GMC_oxred_N PF00732.19 KLO08738.1 - 3.7e-66 223.5 0.0 4.7e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO08738.1 - 1e-33 116.9 0.0 1.7e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KLO08738.1 - 2.8e-05 23.9 1.4 0.00021 21.0 0.3 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO08738.1 - 8.3e-05 22.7 0.2 0.00028 21.1 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KLO08738.1 - 0.00014 21.2 0.4 0.00031 20.1 0.1 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KLO08738.1 - 0.00025 20.2 0.6 0.0012 18.1 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KLO08738.1 - 0.0006 19.0 0.1 0.00091 18.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KLO08738.1 - 0.0014 17.9 0.0 0.0052 16.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO08738.1 - 0.027 13.2 0.2 0.05 12.3 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KLO08738.1 - 0.16 11.2 0.1 0.52 9.5 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase An_peroxidase PF03098.15 KLO08740.1 - 7e-33 114.0 0.0 2.9e-22 78.9 0.0 3.5 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KLO08740.1 - 6.2e-07 28.5 0.5 3.2e-06 26.2 0.0 2.2 3 0 0 3 3 3 1 Cytochrome P450 AATase PF07247.12 KLO08741.1 - 6.8e-21 74.4 0.0 3.3e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase AAA_2 PF07724.14 KLO08742.1 - 4.6e-35 121.2 0.0 1.1e-34 120.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_5 PF13857.6 KLO08742.1 - 7.3e-17 61.2 0.1 7.5e-06 26.1 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KLO08742.1 - 3.5e-16 59.5 0.0 1.8e-08 34.9 0.0 3.7 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KLO08742.1 - 3.4e-15 54.6 0.4 0.0011 19.3 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KLO08742.1 - 1.6e-12 47.3 0.5 0.00042 20.6 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KLO08742.1 - 3.4e-12 46.6 0.9 0.054 14.1 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeats (many copies) AAA_5 PF07728.14 KLO08742.1 - 6.5e-10 39.1 0.0 3.9e-09 36.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KLO08742.1 - 2.1e-07 31.4 0.0 4.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KLO08742.1 - 9.9e-06 25.5 0.1 2.2e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 KLO08742.1 - 8.5e-05 22.3 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KLO08742.1 - 0.0049 16.3 0.0 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KLO08742.1 - 0.014 15.8 0.5 0.17 12.2 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Torsin PF06309.11 KLO08742.1 - 0.022 14.9 0.0 0.083 13.0 0.0 1.9 2 0 0 2 2 2 0 Torsin ABC_tran PF00005.27 KLO08742.1 - 0.034 14.7 0.0 0.14 12.7 0.0 2.1 1 0 0 1 1 1 0 ABC transporter Rtf2 PF04641.12 KLO08742.1 - 0.19 11.0 14.5 0.35 10.2 14.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Zip PF02535.22 KLO08742.1 - 0.24 10.6 1.7 0.36 10.0 1.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 KLO08742.1 - 0.39 9.5 5.6 0.56 9.0 5.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF755 PF05501.11 KLO08742.1 - 1.1 9.6 11.5 2.1 8.7 11.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SAPS PF04499.15 KLO08742.1 - 4.5 6.0 10.5 8.3 5.1 10.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 KLO08742.1 - 4.5 5.9 8.7 7.2 5.3 8.7 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 KLO08742.1 - 7.4 5.2 10.2 12 4.5 10.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Torsin PF06309.11 KLO08743.1 - 0.00063 19.9 0.0 0.00098 19.2 0.0 1.3 1 0 0 1 1 1 1 Torsin AAA_28 PF13521.6 KLO08743.1 - 0.012 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KLO08743.1 - 0.039 14.3 0.0 0.079 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KLO08743.1 - 0.053 13.2 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 KLO08744.1 - 4.2e-31 108.4 0.0 7.9e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_3 PF13606.6 KLO08744.1 - 2.1e-16 58.3 0.3 7.2e-06 26.0 0.1 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 KLO08744.1 - 2.7e-16 59.9 0.0 2.8e-09 37.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KLO08744.1 - 3.2e-12 46.7 0.1 0.00048 20.6 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KLO08744.1 - 6.5e-12 45.3 0.4 1.6e-05 25.1 0.1 4.7 4 0 0 4 4 4 1 Ankyrin repeat AAA_5 PF07728.14 KLO08744.1 - 4.4e-11 42.9 0.0 9.5e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Ank_5 PF13857.6 KLO08744.1 - 4.7e-10 39.5 0.6 1.7e-07 31.4 0.0 4.2 5 1 1 6 6 5 1 Ankyrin repeats (many copies) ClpB_D2-small PF10431.9 KLO08744.1 - 1.7e-07 31.2 0.1 3.1e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KLO08744.1 - 4.2e-07 30.4 0.0 1.1e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KLO08744.1 - 1.3e-06 28.3 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KLO08744.1 - 0.0034 17.2 0.0 0.032 14.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KLO08744.1 - 0.01 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF4611 PF15387.6 KLO08744.1 - 0.017 15.3 0.1 0.035 14.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) AbiTii PF18864.1 KLO08744.1 - 0.04 14.1 0.5 0.082 13.1 0.5 1.4 1 0 0 1 1 1 0 AbiTii Torsin PF06309.11 KLO08744.1 - 0.049 13.7 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_22 PF13401.6 KLO08744.1 - 0.064 13.5 0.0 0.24 11.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KLO08744.1 - 0.066 13.6 0.0 0.42 11.0 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.6 KLO08744.1 - 0.095 12.5 0.1 0.63 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Coatomer_E PF04733.14 KLO08745.1 - 1.5e-39 136.2 0.0 1.7e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_8 PF13181.6 KLO08745.1 - 0.00015 21.7 0.2 0.0057 16.8 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KLO08745.1 - 0.012 15.7 4.3 1 9.6 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KLO08745.1 - 0.021 15.3 2.9 0.24 11.9 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KLO08745.1 - 0.12 12.2 0.1 17 5.4 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KLO08745.1 - 0.19 11.9 4.9 1.2 9.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KLO08745.1 - 1.1 9.2 3.0 37 4.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KLO08745.1 - 3 8.9 10.6 2.8 9.0 0.3 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KLO08745.1 - 6.8 7.4 6.6 39 5.0 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Tmemb_18A PF09771.9 KLO08746.1 - 0.0037 17.6 0.1 0.0046 17.3 0.1 1.3 1 1 0 1 1 1 1 Transmembrane protein 188 DUF3382 PF11862.8 KLO08746.1 - 0.1 12.9 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) AATase PF07247.12 KLO08747.1 - 1.3e-27 96.5 0.0 2.1e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Alcohol acetyltransferase AAA_2 PF07724.14 KLO08748.1 - 2.7e-35 122.0 0.2 5.7e-35 120.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.7 KLO08748.1 - 2.4e-22 79.3 0.2 6.1e-10 39.6 0.2 4.8 4 1 0 4 4 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KLO08748.1 - 2.1e-18 64.5 2.8 0.00059 20.1 0.1 5.3 5 0 0 5 5 4 4 Ankyrin repeat Ank_5 PF13857.6 KLO08748.1 - 2.8e-16 59.4 0.1 1.3e-05 25.4 0.0 5.2 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KLO08748.1 - 2.2e-14 53.1 2.4 0.00012 22.3 0.4 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KLO08748.1 - 1.2e-12 48.0 0.1 0.014 16.0 0.0 4.8 4 1 1 5 5 4 4 Ankyrin repeats (many copies) AAA_5 PF07728.14 KLO08748.1 - 5.7e-10 39.3 0.1 3.3e-09 36.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KLO08748.1 - 1.7e-07 31.7 0.0 4.4e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KLO08748.1 - 5.7e-07 29.5 0.1 1.6e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 KLO08748.1 - 0.00013 21.7 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KLO08748.1 - 0.0062 15.9 0.0 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KLO08748.1 - 0.01 16.3 0.0 0.35 11.2 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain Torsin PF06309.11 KLO08748.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.27 KLO08748.1 - 0.062 13.8 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter SR-25 PF10500.9 KLO08748.1 - 0.15 11.6 10.9 0.27 10.8 10.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_33 PF13671.6 KLO08748.1 - 0.28 11.3 1.4 3.4 7.8 0.1 2.9 4 0 0 4 4 4 0 AAA domain SRP-alpha_N PF04086.13 KLO08748.1 - 1.1 9.2 10.2 2.1 8.2 10.2 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal AAA_2 PF07724.14 KLO08749.1 - 3.4e-38 131.4 0.0 6.1e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.7 KLO08749.1 - 1.9e-18 66.8 0.1 5.4e-11 42.9 0.8 3.9 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KLO08749.1 - 2.2e-16 60.0 0.6 0.00021 21.8 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KLO08749.1 - 3.8e-11 42.2 3.1 0.0014 18.9 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KLO08749.1 - 8.4e-11 41.9 0.4 0.0093 16.3 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeats (many copies) AAA_5 PF07728.14 KLO08749.1 - 4e-10 39.8 0.0 2e-09 37.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Ank PF00023.30 KLO08749.1 - 1.3e-09 38.0 7.0 0.0044 17.4 0.1 5.5 6 0 0 6 6 6 2 Ankyrin repeat AAA PF00004.29 KLO08749.1 - 1.3e-07 32.1 0.0 2.9e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KLO08749.1 - 1.4e-05 25.0 0.0 3.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 KLO08749.1 - 6.7e-05 22.7 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Torsin PF06309.11 KLO08749.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_16 PF13191.6 KLO08749.1 - 0.004 17.6 0.1 0.076 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 KLO08749.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KLO08749.1 - 0.042 13.1 0.1 0.33 10.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin HU-DNA_bdg PF14848.6 KLO08749.1 - 0.043 13.8 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 DNA-binding domain AAA_3 PF07726.11 KLO08749.1 - 0.078 12.8 0.0 2.1 8.2 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) 3-HAO PF06052.12 KLO08750.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase FAD-SLDH PF12318.8 KLO08752.1 - 0.013 15.6 0.3 0.017 15.2 0.3 1.1 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase 2OG-FeII_Oxy_2 PF13532.6 KLO08752.1 - 0.025 14.8 1.1 0.029 14.5 1.1 1.1 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PHTB1_C PF14728.6 KLO08752.1 - 0.18 10.8 0.9 0.21 10.7 0.9 1.0 1 0 0 1 1 1 0 PTHB1 C-terminus TFIIA PF03153.13 KLO08753.1 - 2.2 8.2 18.1 2.5 8.0 18.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-MYND PF01753.18 KLO08754.1 - 1.2e-07 31.7 15.9 1.2e-07 31.7 15.9 2.8 2 1 1 3 3 3 1 MYND finger zf-MYND PF01753.18 KLO08755.1 - 1.3e-08 34.8 15.7 1.3e-08 34.8 15.7 2.4 2 0 0 2 2 2 1 MYND finger INTS5_N PF14837.6 KLO08755.1 - 0.23 11.0 2.6 14 5.2 0.1 3.1 3 0 0 3 3 3 0 Integrator complex subunit 5 N-terminus zf-Mss51 PF13824.6 KLO08755.1 - 1.4 9.0 8.0 0.65 10.1 4.1 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO08756.1 - 5.1e-09 36.1 10.6 1.3e-08 34.8 10.6 1.7 1 0 0 1 1 1 1 MYND finger WD40 PF00400.32 KLO08758.1 - 2.4e-25 88.3 11.7 4.5e-09 36.8 0.4 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.14 KLO08758.1 - 3.2e-25 88.2 8.5 7.6e-25 87.0 8.5 1.7 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 KLO08758.1 - 3.1e-06 27.4 0.0 0.41 11.0 0.1 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WDCP PF15390.6 KLO08758.1 - 0.031 12.7 0.6 0.047 12.1 0.6 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family AMP-binding PF00501.28 KLO08759.1 - 2.5e-97 326.1 0.6 3.5e-97 325.7 0.2 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KLO08759.1 - 3.6e-25 88.7 0.5 5.1e-24 85.0 0.1 3.0 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KLO08759.1 - 3.6e-13 49.2 0.4 3.6e-13 49.2 0.4 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Crp PF00325.20 KLO08759.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family DUF2461 PF09365.10 KLO08760.1 - 2e-65 220.7 0.0 2.9e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Macoilin PF09726.9 KLO08760.1 - 1.1 7.7 4.8 1.3 7.5 4.8 1.1 1 0 0 1 1 1 0 Macoilin family Pox_Ag35 PF03286.14 KLO08760.1 - 1.3 8.8 31.5 0.14 11.9 7.5 2.2 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Trp_halogenase PF04820.14 KLO08762.1 - 0.00039 19.4 0.1 0.25 10.1 0.0 2.7 3 0 0 3 3 3 2 Tryptophan halogenase FAD_oxidored PF12831.7 KLO08762.1 - 0.0059 16.0 0.0 0.024 14.0 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO08762.1 - 0.12 11.4 0.1 2.6 7.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 KLO08763.1 - 0.00026 20.5 0.0 0.00049 19.6 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KLO08763.1 - 0.0011 17.9 0.3 0.12 11.2 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 KLO08763.1 - 0.088 12.0 0.1 0.86 8.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KLO08764.1 - 0.013 14.9 0.0 0.041 13.2 0.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase UPF0227 PF05728.12 KLO08764.1 - 0.22 11.4 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) F-box-like PF12937.7 KLO08765.1 - 1.9e-07 30.9 0.7 7.3e-07 29.0 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KLO08765.1 - 0.1 12.6 0.2 0.54 10.3 0.2 2.3 2 1 0 2 2 2 0 F-box-like domain FAD_oxidored PF12831.7 KLO08766.1 - 0.23 10.8 0.0 1.2 8.3 0.0 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_6 PF08030.12 KLO08768.1 - 4.6e-39 134.0 0.0 7.1e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KLO08768.1 - 7.8e-21 74.2 0.0 1.8e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KLO08768.1 - 3.9e-18 65.8 10.3 3.9e-18 65.8 10.3 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KLO08768.1 - 0.15 12.7 0.0 0.78 10.4 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Acetyltransf_1 PF00583.25 KLO08769.1 - 1.4e-07 31.7 0.0 1.9e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KLO08769.1 - 8.5e-07 29.0 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO08769.1 - 9.5e-06 26.0 0.1 2.1e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KLO08769.1 - 9.8e-06 25.7 0.1 2.2e-05 24.5 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO08769.1 - 0.028 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein VIT1 PF01988.19 KLO08771.1 - 1.9e-62 211.0 3.1 2.3e-62 210.7 3.1 1.1 1 0 0 1 1 1 1 VIT family VIT1 PF01988.19 KLO08772.1 - 1.8e-65 220.8 4.9 2.2e-65 220.6 4.9 1.1 1 0 0 1 1 1 1 VIT family SLATT_fungal PF18142.1 KLO08772.1 - 0.48 10.4 0.0 0.48 10.4 0.0 2.3 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Herpes_UL17 PF04559.12 KLO08774.1 - 0.15 10.8 0.3 0.15 10.8 0.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL17 protein HABP4_PAI-RBP1 PF04774.15 KLO08775.1 - 4.6e-05 24.2 1.1 6.1e-05 23.8 1.1 1.4 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family FAA_hydro_N_2 PF18288.1 KLO08775.1 - 0.046 14.1 0.0 0.096 13.1 0.0 1.5 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 Exo_endo_phos PF03372.23 KLO08776.1 - 4.3e-12 46.1 0.2 7.4e-12 45.3 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 KLO08776.1 - 8.1e-11 42.0 0.0 3.7e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain PapD-like PF14874.6 KLO08776.1 - 0.00015 21.8 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 Flagellar-associated PapD-like Motile_Sperm PF00635.26 KLO08776.1 - 0.00056 19.7 0.1 0.0013 18.5 0.1 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain INPP5B_PH PF16776.5 KLO08776.1 - 0.097 12.4 0.0 0.48 10.1 0.0 2.1 2 1 0 2 2 2 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain TPR_12 PF13424.6 KLO08777.1 - 1.4e-07 31.6 5.4 0.034 14.4 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO08777.1 - 1.8e-05 24.5 4.0 1.4 9.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KLO08777.1 - 3.6e-05 23.4 1.4 1.4 8.8 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KLO08777.1 - 6.2e-05 23.4 3.2 2 9.0 0.5 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 KLO08777.1 - 0.0011 19.3 0.5 0.22 11.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KLO08777.1 - 0.0012 18.6 4.6 0.31 11.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KLO08777.1 - 0.0027 18.4 11.4 3.1 8.8 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KLO08777.1 - 0.014 15.6 1.4 15 6.1 0.0 4.5 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KLO08777.1 - 0.057 13.5 2.4 0.78 9.9 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat FAD_binding_4 PF01565.23 KLO08778.1 - 2.6e-22 79.1 2.8 2.6e-22 79.1 2.8 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KLO08778.1 - 3.1e-05 24.0 0.0 6.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KLO08779.1 - 2e-22 79.4 0.6 3.1e-22 78.8 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KLO08779.1 - 0.00025 21.1 0.0 0.00052 20.0 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like XPG_I PF00867.18 KLO08780.1 - 7.7e-27 93.5 0.0 2.5e-26 91.9 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KLO08780.1 - 3.7e-22 78.7 0.0 7.8e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KLO08780.1 - 0.0047 17.5 0.5 0.068 13.8 0.0 3.1 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.20 KLO08780.1 - 0.73 9.9 13.7 1.4 9.0 2.9 3.1 1 1 1 2 2 2 0 Ubiquitin interaction motif NDUF_B8 PF05821.11 KLO08781.1 - 1e-08 35.3 0.2 1.8e-08 34.4 0.2 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Methyltransf_25 PF13649.6 KLO08782.1 - 3.5e-18 66.1 0.0 7.2e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO08782.1 - 9.4e-15 55.0 0.0 1.8e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO08782.1 - 3.6e-09 36.7 0.0 6.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO08782.1 - 1.8e-08 35.0 0.0 3.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO08782.1 - 3.4e-08 33.1 0.0 5.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KLO08782.1 - 4.3e-07 29.9 0.0 7.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO08782.1 - 9.4e-05 22.0 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KLO08782.1 - 0.0011 18.5 0.0 0.0042 16.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 KLO08782.1 - 0.0037 16.6 0.0 0.0058 15.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KLO08782.1 - 0.063 13.4 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 KLO08782.1 - 0.087 11.4 0.0 0.18 10.3 0.0 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SH3_1 PF00018.28 KLO08783.1 - 4.4e-14 51.8 0.4 6.5e-14 51.3 0.4 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KLO08783.1 - 1.9e-13 50.0 0.2 2.9e-13 49.5 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KLO08783.1 - 4.8e-12 45.4 0.1 8.1e-12 44.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Voldacs PF03517.13 KLO08784.1 - 2.6e-28 98.9 0.4 4e-28 98.3 0.4 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF2213 PF09979.9 KLO08784.1 - 0.16 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) ANAPC4_WD40 PF12894.7 KLO08786.1 - 0.00022 21.5 0.0 0.43 10.9 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup88 PF10168.9 KLO08786.1 - 0.088 10.6 1.1 0.13 10.0 1.1 1.2 1 0 0 1 1 1 0 Nuclear pore component Syntaxin-6_N PF09177.11 KLO08786.1 - 0.25 11.9 1.5 0.74 10.4 1.2 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal NUDIX PF00293.28 KLO08787.1 - 8e-13 48.6 0.0 1.5e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Kelch_5 PF13854.6 KLO08789.1 - 1.7e-19 69.4 0.7 3.8e-05 23.6 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 KLO08789.1 - 4e-19 68.3 7.7 8.5e-07 28.9 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KLO08789.1 - 1.1e-18 67.1 9.7 4.7e-06 26.8 0.1 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KLO08789.1 - 1.7e-13 50.3 10.7 3.7e-05 23.8 0.1 5.6 3 1 2 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KLO08789.1 - 9.6e-13 47.6 4.1 0.013 15.4 0.0 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KLO08789.1 - 1.1e-10 40.9 0.0 0.0042 16.6 0.0 4.4 4 0 0 4 4 4 3 Kelch motif ACBP PF00887.19 KLO08791.1 - 7.8e-28 96.5 0.6 9.3e-28 96.3 0.6 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein PH PF00169.29 KLO08792.1 - 2.5e-30 105.1 0.9 1.3e-17 64.2 0.2 3.2 3 0 0 3 3 3 3 PH domain PH_11 PF15413.6 KLO08792.1 - 3.3e-14 53.2 9.3 1.6e-05 25.3 4.6 4.2 3 1 0 3 3 3 3 Pleckstrin homology domain PH_8 PF15409.6 KLO08792.1 - 5.5e-09 36.2 1.7 0.00013 22.2 0.2 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 KLO08792.1 - 7.8e-08 32.4 0.3 0.016 15.3 0.1 3.8 3 1 0 3 3 3 2 PH domain PH_9 PF15410.6 KLO08792.1 - 1.4e-05 25.4 3.7 0.69 10.3 0.1 4.1 2 2 1 3 3 3 2 Pleckstrin homology domain PH_13 PF16652.5 KLO08792.1 - 0.0024 17.7 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.6 KLO08792.1 - 0.12 12.2 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Fungal_trans_2 PF11951.8 KLO08795.1 - 6.9e-30 104.1 0.0 8.9e-29 100.5 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO08795.1 - 0.0003 20.8 8.5 0.00052 20.1 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO08797.1 - 0.00039 20.5 6.8 0.0005 20.1 6.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KLO08799.1 - 8.1e-38 130.2 0.4 5.9e-19 68.1 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Drf_GBD PF06371.13 KLO08801.1 - 4e-16 59.1 0.0 1.6e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain PI3Ka PF00613.20 KLO08802.1 - 2.5e-52 177.0 0.0 3.9e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KLO08802.1 - 3.5e-46 158.0 0.0 5e-31 108.4 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KLO08802.1 - 1.9e-40 138.0 0.0 3.4e-40 137.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Aminotran_3 PF00202.21 KLO08803.1 - 1.7e-45 155.4 0.0 1.1e-43 149.5 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 KLO08803.1 - 4.9e-18 65.7 0.0 1.4e-17 64.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain RAG2_PHD PF13341.6 KLO08804.1 - 0.00031 20.7 0.1 0.00035 20.6 0.1 1.1 1 0 0 1 1 1 1 RAG2 PHD domain NDUFB10 PF10249.9 KLO08804.1 - 0.003 18.1 0.7 0.0031 18.0 0.7 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 MitoNEET_N PF10660.9 KLO08805.1 - 0.037 14.1 0.1 0.07 13.2 0.1 1.4 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Aminotran_5 PF00266.19 KLO08806.1 - 1.1e-19 70.7 0.0 2.3e-19 69.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KLO08806.1 - 1.4e-08 34.3 0.0 2.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KLO08806.1 - 0.0013 18.1 0.0 0.064 12.6 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Cu-oxidase_2 PF07731.14 KLO08806.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Multicopper oxidase SMN PF06003.12 KLO08809.1 - 0.1 11.9 0.5 0.17 11.1 0.5 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Sigma70_ner PF04546.13 KLO08811.1 - 0.27 11.1 10.1 0.059 13.3 1.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region F-box-like PF12937.7 KLO08813.1 - 7.6e-08 32.1 0.5 7.6e-08 32.1 0.5 2.8 2 2 0 2 2 2 1 F-box-like CaATP_NAI PF12515.8 KLO08813.1 - 0.028 14.0 0.5 3.1 7.5 0.1 2.6 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain Corona_7 PF02398.16 KLO08813.1 - 0.1 13.2 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Coronavirus protein 7 F-box PF00646.33 KLO08813.1 - 0.12 12.2 2.6 2.1 8.3 2.6 2.9 1 1 0 1 1 1 0 F-box domain E1-E2_ATPase PF00122.20 KLO08815.1 - 3.9e-48 163.4 0.3 3.9e-48 163.4 0.3 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KLO08815.1 - 8.5e-32 111.1 4.8 8.8e-31 107.8 2.1 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KLO08815.1 - 1e-23 83.5 1.6 8e-11 42.2 0.5 3.9 4 0 0 4 4 4 3 Heavy-metal-associated domain HAD PF12710.7 KLO08815.1 - 0.0014 19.0 0.0 0.0039 17.6 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KLO08815.1 - 0.0019 18.0 0.2 0.0037 17.1 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Importin_rep_3 PF18806.1 KLO08815.1 - 0.12 12.4 0.1 0.36 10.9 0.1 1.7 1 0 0 1 1 1 0 Importin 13 repeat NACHT PF05729.12 KLO08817.1 - 4e-17 62.6 0.3 9.3e-12 45.2 0.0 3.0 2 1 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 KLO08817.1 - 8.1e-09 35.9 0.0 0.00021 21.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KLO08817.1 - 1.1e-08 35.7 0.0 0.00076 19.9 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain ATPase_2 PF01637.18 KLO08817.1 - 3.5e-07 30.4 0.0 0.00021 21.3 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA PF00004.29 KLO08817.1 - 2.9e-06 27.7 0.0 0.0014 19.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KLO08817.1 - 0.00077 18.6 0.5 0.38 9.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KLO08817.1 - 0.0018 17.5 0.0 1.5 7.9 0.0 2.5 2 1 0 2 2 2 2 NB-ARC domain RNA_helicase PF00910.22 KLO08817.1 - 0.015 15.7 0.2 1.2 9.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KLO08817.1 - 0.047 14.2 0.3 0.22 12.1 0.3 2.2 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KLO08817.1 - 0.06 13.2 1.1 1.7 8.5 0.3 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_25 PF13481.6 KLO08817.1 - 0.33 10.5 1.7 6.9 6.2 0.3 2.9 3 0 0 3 3 3 0 AAA domain UQ_con PF00179.26 KLO08818.1 - 4.8e-21 74.9 0.0 9e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 KLO08818.1 - 0.003 17.4 1.2 0.0082 16.0 1.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain zf-dskA_traR PF01258.17 KLO08818.1 - 0.033 14.1 0.1 0.098 12.6 0.1 1.8 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger Mito_carr PF00153.27 KLO08819.1 - 4.8e-46 154.6 2.8 6.2e-16 58.1 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 KLO08819.1 - 0.045 13.9 0.1 8.5 6.6 0.0 2.5 2 0 0 2 2 2 0 PrcB C-terminal Opy2 PF09463.10 KLO08820.1 - 7.9e-05 22.9 21.0 0.00013 22.2 21.0 1.4 1 0 0 1 1 1 1 Opy2 protein ABC_tran PF00005.27 KLO08821.1 - 4.9e-17 62.7 0.0 1.2e-16 61.4 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KLO08821.1 - 1.1e-11 45.1 4.0 3.8e-05 23.7 0.1 2.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KLO08821.1 - 0.00016 21.3 0.2 0.00046 19.9 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 KLO08821.1 - 0.00098 18.8 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KLO08821.1 - 0.0043 16.3 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 KLO08821.1 - 0.0058 16.6 0.1 0.0092 15.9 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 KLO08821.1 - 0.0062 16.1 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KLO08821.1 - 0.0066 16.2 0.1 0.0097 15.6 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KLO08821.1 - 0.014 15.9 0.2 0.022 15.3 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KLO08821.1 - 0.046 14.1 0.1 0.084 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KLO08821.1 - 0.058 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KLO08821.1 - 0.064 13.3 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KLO08821.1 - 0.066 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KLO08821.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SMC_N PF02463.19 KLO08821.1 - 0.11 11.9 0.1 0.68 9.3 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 KLO08821.1 - 0.14 12.3 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 Dynamin family NACHT PF05729.12 KLO08821.1 - 0.16 11.9 0.0 0.42 10.5 0.1 1.7 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 KLO08821.1 - 0.18 11.1 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family F-box-like PF12937.7 KLO08822.1 - 5.8e-06 26.1 0.3 2.2e-05 24.3 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO08822.1 - 6.3e-05 22.8 0.2 0.0002 21.1 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO08824.1 - 1.8e-07 30.9 0.8 5.6e-07 29.4 0.8 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO08824.1 - 0.13 12.2 3.6 1.6 8.7 3.6 2.6 1 1 0 1 1 1 0 F-box domain NACHT PF05729.12 KLO08826.1 - 2.8e-13 50.1 0.5 2.3e-09 37.4 0.1 3.6 3 2 0 3 3 3 2 NACHT domain AAA_16 PF13191.6 KLO08826.1 - 4.9e-09 36.8 0.0 5e-05 23.8 0.0 3.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KLO08826.1 - 1.2e-08 35.3 0.0 0.005 17.1 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 KLO08826.1 - 0.00077 19.9 0.1 0.43 11.0 0.0 3.3 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KLO08826.1 - 0.005 16.8 0.4 0.52 10.2 0.1 2.9 3 0 0 3 3 3 1 Adenylylsulphate kinase KAP_NTPase PF07693.14 KLO08826.1 - 0.063 12.5 0.3 0.99 8.6 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Parvo_NS1 PF01057.17 KLO08826.1 - 0.094 11.8 0.1 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Torsin PF06309.11 KLO08826.1 - 0.11 12.6 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 Torsin Sugar_tr PF00083.24 KLO08828.1 - 3.4e-124 415.2 14.3 4.4e-124 414.8 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO08828.1 - 6.2e-17 61.6 35.1 3.3e-15 55.9 19.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Cation_ATPase_C PF00689.21 KLO08829.1 - 0.00023 20.9 0.0 0.00026 20.7 0.0 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus ATP_bind_3 PF01171.20 KLO08830.1 - 3.1e-17 62.9 0.0 6.4e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KLO08830.1 - 1.3e-16 59.8 9.6 2.6e-16 58.8 2.6 4.0 4 0 0 4 4 4 1 Zinc-ribbon HIPIP PF01355.17 KLO08830.1 - 0.00088 19.6 1.3 4.5 7.7 0.7 3.5 3 0 0 3 3 3 2 High potential iron-sulfur protein RecR PF02132.15 KLO08830.1 - 0.012 15.1 1.2 0.012 15.1 1.2 2.8 4 0 0 4 4 4 0 RecR protein tRNA_Me_trans PF03054.16 KLO08830.1 - 0.034 12.9 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase ThiI PF02568.14 KLO08830.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Whib PF02467.16 KLO08830.1 - 0.17 12.5 0.2 0.17 12.5 0.2 2.5 3 1 0 3 3 3 0 Transcription factor WhiB TF_Zn_Ribbon PF08271.12 KLO08830.1 - 0.63 9.6 10.2 1.1 8.8 0.2 3.6 3 1 1 4 4 3 0 TFIIB zinc-binding SurE PF01975.17 KLO08831.1 - 4.8e-35 121.1 0.3 6.3e-35 120.7 0.3 1.1 1 0 0 1 1 1 1 Survival protein SurE SurE PF01975.17 KLO08832.1 - 3.5e-31 108.5 2.6 3.6e-31 108.4 2.0 1.3 1 1 0 1 1 1 1 Survival protein SurE UbiA PF01040.18 KLO08833.1 - 4.8e-20 71.9 11.7 6.1e-20 71.6 11.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Cas9_b_hairpin PF17893.1 KLO08846.1 - 0.19 11.6 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain SPATA1_C PF15743.5 KLO08849.1 - 0.0023 18.0 0.4 0.0071 16.4 0.4 1.8 1 0 0 1 1 1 1 Spermatogenesis-associated C-terminus Calponin PF00402.18 KLO08850.1 - 0.00072 19.2 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 Calponin family repeat FlaC_arch PF05377.11 KLO08851.1 - 0.098 13.1 0.8 0.2 12.1 0.8 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF4094 PF13334.6 KLO08851.1 - 0.22 12.0 1.0 0.7 10.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) PKcGMP_CC PF16808.5 KLO08851.1 - 0.23 11.4 2.0 0.6 10.0 2.0 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RCDG1 PF15725.5 KLO08852.1 - 0.062 13.7 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Syntaxin-6_N PF09177.11 KLO08856.1 - 0.047 14.2 0.0 0.063 13.8 0.0 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal p450 PF00067.22 KLO08857.1 - 1.3e-60 205.5 0.0 1.8e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_4 PF13894.6 KLO08858.1 - 0.22 12.5 3.5 13 6.9 0.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger OGFr_III PF04680.13 KLO08858.1 - 7.3 7.4 7.7 39 5.1 0.9 3.2 2 0 0 2 2 2 0 Opioid growth factor receptor repeat zf-C2H2_4 PF13894.6 KLO08859.1 - 0.011 16.5 0.4 0.44 11.5 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf_Hakai PF18408.1 KLO08859.1 - 0.15 11.8 0.6 0.41 10.4 0.6 1.8 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain zf-C2H2 PF00096.26 KLO08859.1 - 0.27 11.8 8.3 0.78 10.3 0.5 2.9 2 1 0 2 2 2 0 Zinc finger, C2H2 type p450 PF00067.22 KLO08860.1 - 0.012 14.3 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 DUF5601 PF18151.1 KLO08861.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) Plavaka PF18759.1 KLO08862.1 - 7.9e-110 367.1 0.1 1e-109 366.7 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KLO08862.1 - 0.00096 19.5 0.5 0.0046 17.3 0.5 2.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO08862.1 - 0.19 12.7 4.0 0.23 12.4 1.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Sgf11 PF08209.11 KLO08862.1 - 0.62 9.7 3.4 1 9.0 1.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Tir_receptor_C PF07489.11 KLO08863.1 - 0.3 11.1 6.3 0.44 10.5 6.3 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus p450 PF00067.22 KLO08865.1 - 1e-36 126.7 0.1 1.2e-36 126.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.22 KLO08866.1 - 9.3e-12 44.6 0.0 1.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad10 PF03834.14 KLO08867.1 - 8.6e-47 157.9 0.1 1.4e-46 157.2 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KLO08867.1 - 7.3e-06 26.5 0.0 0.00017 22.1 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KLO08867.1 - 0.0024 17.9 0.0 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.23 KLO08867.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DASH_Dad1 PF08649.10 KLO08867.1 - 0.16 12.2 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad1 HRDC PF00570.23 KLO08867.1 - 0.18 11.8 0.0 0.73 9.9 0.0 2.0 2 0 0 2 2 2 0 HRDC domain Lactamase_B PF00753.27 KLO08868.1 - 1.2e-12 48.3 0.2 2.7e-12 47.1 0.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KLO08868.1 - 0.0054 16.3 0.2 0.014 14.9 0.2 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Amidohydro_1 PF01979.20 KLO08869.1 - 2.8e-68 230.7 1.1 4.2e-68 230.2 1.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KLO08869.1 - 4e-55 185.3 0.9 9.7e-55 184.1 0.9 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KLO08869.1 - 1.1e-41 140.8 0.2 2.8e-41 139.5 0.2 1.7 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KLO08869.1 - 1.9e-40 137.1 0.1 5.8e-40 135.6 0.1 1.9 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KLO08869.1 - 0.00036 20.1 0.3 0.039 13.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family FAD_binding_3 PF01494.19 KLO08870.1 - 5.5e-08 32.4 0.0 6.9e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KLO08870.1 - 3.9e-06 27.0 0.0 9.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KLO08870.1 - 5.3e-06 26.0 0.0 0.00032 20.1 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KLO08870.1 - 6.2e-06 25.6 0.0 7.7e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO08870.1 - 6.4e-05 22.7 0.0 0.00039 20.1 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase ApbA PF02558.16 KLO08870.1 - 0.0076 15.9 0.0 0.024 14.3 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KLO08870.1 - 0.014 16.0 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KLO08870.1 - 0.031 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KLO08870.1 - 0.15 10.7 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein zf-MYND PF01753.18 KLO08871.1 - 2.6e-10 40.2 15.9 4.2e-10 39.5 15.9 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO08871.1 - 0.00044 20.3 10.5 0.00094 19.2 10.5 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO08872.1 - 1.2e-06 28.5 7.4 2e-06 27.8 7.4 1.3 1 0 0 1 1 1 1 MYND finger ATP-grasp_6 PF18419.1 KLO08872.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp-like domain zf-Mss51 PF13824.6 KLO08872.1 - 0.15 12.1 4.3 0.38 10.9 4.3 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-H2C2_2 PF13465.6 KLO08874.1 - 0.06 13.8 0.8 0.06 13.8 0.8 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Zn_ribbon_SprT PF17283.2 KLO08874.1 - 0.11 12.5 2.7 0.27 11.2 2.7 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2 PF00096.26 KLO08874.1 - 1.5 9.4 13.3 0.22 12.0 1.9 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Pol_alpha_B_N PF08418.10 KLO08874.1 - 2.7 7.9 5.0 4.1 7.3 0.9 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal zf-C2H2_4 PF13894.6 KLO08874.1 - 9 7.4 7.8 4.7 8.3 0.7 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-MYND PF01753.18 KLO08875.1 - 4e-07 30.0 7.7 4e-07 30.0 7.7 1.8 2 0 0 2 2 2 1 MYND finger IFRD PF05004.13 KLO08875.1 - 0.0053 15.9 0.4 0.018 14.2 0.3 1.9 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) zf-RING_12 PF17976.1 KLO08875.1 - 0.96 9.8 6.9 5.7 7.3 0.1 3.2 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-C2H2_4 PF13894.6 KLO08876.1 - 0.0067 17.2 2.1 0.033 15.0 0.7 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO08876.1 - 0.012 16.0 3.1 0.035 14.6 1.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KLO08876.1 - 0.07 13.8 0.1 0.14 12.8 0.1 1.5 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-DNA_Pol PF08996.10 KLO08876.1 - 0.082 12.6 0.4 0.13 12.0 0.4 1.3 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-C2H2_11 PF16622.5 KLO08876.1 - 0.16 11.7 2.2 0.31 10.8 0.5 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-MYND PF01753.18 KLO08877.1 - 5.7e-09 35.9 11.8 1.8e-08 34.3 11.8 2.0 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO08878.1 - 5.1e-09 36.1 11.0 1.1e-08 35.0 11.0 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO08878.1 - 0.5 10.5 3.5 1.1 9.4 3.5 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-RING_12 PF17976.1 KLO08878.1 - 0.59 10.4 4.2 0.46 10.8 0.1 2.8 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C6H2 PF15801.5 KLO08878.1 - 3.6 8.0 8.7 9 6.7 8.7 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KLO08879.1 - 1.1e-09 38.1 9.7 2.2e-09 37.2 9.7 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO08879.1 - 0.0039 17.2 2.0 0.0088 16.1 2.0 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KLO08879.1 - 1.3 9.3 8.5 3.1 8.2 8.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KLO08880.1 - 1e-09 38.3 14.2 1e-09 38.3 14.2 2.2 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KLO08880.1 - 3.9 7.9 11.4 14 6.1 10.9 2.3 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KLO08880.1 - 4.5 7.4 7.2 9.8 6.4 7.2 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Helicase_C PF00271.31 KLO08881.1 - 5.1e-16 59.0 0.6 1.5e-15 57.5 0.3 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AA_kinase PF00696.28 KLO08881.1 - 0.073 12.6 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Amino acid kinase family Transposase_21 PF02992.14 KLO08882.1 - 3.1e-05 23.3 0.0 5.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 KLO08882.1 - 0.0035 16.6 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase DUF1258 PF06869.12 KLO08882.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Bile_Hydr_Trans PF04775.14 KLO08882.1 - 0.037 14.1 0.1 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region Pkinase_Tyr PF07714.17 KLO08884.1 - 2.6e-32 112.1 0.0 3.2e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08884.1 - 3.2e-30 105.4 0.0 3.7e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO08884.1 - 0.00024 20.5 0.0 0.00099 18.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KLO08884.1 - 0.015 14.7 0.1 0.02 14.3 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO08884.1 - 0.019 14.9 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KLO08884.1 - 0.055 13.1 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Myticin-prepro PF10690.9 KLO08885.1 - 0.0083 16.4 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel RuBisCO_small PF00101.20 KLO08885.1 - 0.023 14.7 0.1 0.061 13.3 0.1 1.7 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain PIG-F PF06699.11 KLO08885.1 - 0.25 11.5 1.2 0.19 11.9 0.1 1.3 1 1 0 1 1 1 0 GPI biosynthesis protein family Pig-F Pkinase_Tyr PF07714.17 KLO08886.1 - 3.7e-53 180.4 0.0 1.2e-32 113.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KLO08886.1 - 6.1e-50 170.0 0.0 1.7e-27 96.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KLO08886.1 - 1.8e-05 24.8 0.4 0.059 13.3 0.0 2.8 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KLO08886.1 - 0.001 18.5 0.0 0.023 14.1 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KLO08886.1 - 0.0015 17.9 0.0 0.0079 15.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KLO08886.1 - 0.0069 16.0 0.0 3.9 7.0 0.0 2.3 2 0 0 2 2 2 2 RIO1 family WaaY PF06176.11 KLO08886.1 - 0.057 13.0 0.1 0.46 10.1 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.17 KLO08887.1 - 1.6e-34 119.4 0.0 6e-34 117.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08887.1 - 2.3e-29 102.6 0.0 3.6e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO08887.1 - 0.12 12.2 0.2 1.2 9.0 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KLO08889.1 - 9.7e-40 136.5 0.0 1.9e-39 135.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08889.1 - 5.7e-33 114.4 0.0 9e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KLO08889.1 - 0.0016 17.8 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO08889.1 - 0.0056 16.6 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO08889.1 - 0.0069 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KLO08890.1 - 1.8e-58 197.9 0.0 1.6e-40 139.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KLO08890.1 - 9.5e-57 192.3 0.0 4.7e-35 121.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KLO08890.1 - 2.1e-06 27.8 0.0 0.002 18.1 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO08890.1 - 8.7e-06 25.2 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KLO08890.1 - 5.3e-05 22.7 0.2 0.027 13.8 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 KLO08890.1 - 0.011 15.4 0.1 0.094 12.3 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KLO08890.1 - 0.011 15.3 0.0 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 RIO1 family FTA2 PF13095.6 KLO08890.1 - 0.018 14.7 0.0 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KLO08890.1 - 0.023 13.5 0.1 0.11 11.2 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase DUF4714 PF15833.5 KLO08893.1 - 0.042 13.8 0.2 0.077 13.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) BTB PF00651.31 KLO08897.1 - 0.00014 22.0 0.0 0.00023 21.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO08898.1 - 0.001 19.3 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_S28 PF05577.12 KLO08900.1 - 1.7e-55 188.5 3.6 3.5e-37 128.2 1.2 2.7 2 1 0 2 2 2 2 Serine carboxypeptidase S28 STE3 PF02076.15 KLO08902.1 - 1.1e-56 192.2 16.5 1.8e-56 191.5 16.5 1.3 1 1 0 1 1 1 1 Pheromone A receptor GLTP PF08718.11 KLO08903.1 - 4e-31 108.3 0.0 4.9e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) GvpD PF07088.11 KLO08904.1 - 0.15 10.7 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein zf-C2H2 PF00096.26 KLO08905.1 - 2.7e-13 49.6 9.2 1.4e-06 28.5 1.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KLO08905.1 - 5.2e-09 36.1 14.0 2.8e-05 24.3 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KLO08905.1 - 8.6e-09 35.5 7.5 0.00067 20.3 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KLO08905.1 - 0.00011 22.0 9.2 0.036 14.0 1.4 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-met PF12874.7 KLO08905.1 - 0.00061 20.1 2.1 0.022 15.1 0.8 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KLO08905.1 - 0.0031 17.2 2.6 0.092 12.5 0.3 2.2 2 0 0 2 2 2 1 zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 KLO08905.1 - 0.0079 16.1 2.2 0.11 12.4 0.1 2.2 2 0 0 2 2 2 1 SprT-like zinc ribbon domain zf-C2H2_jaz PF12171.8 KLO08905.1 - 0.01 16.1 8.3 0.012 15.9 0.7 2.3 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 KLO08905.1 - 0.022 15.4 1.6 0.031 15.0 1.6 1.2 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2HE PF16278.5 KLO08905.1 - 0.024 15.1 0.2 0.024 15.1 0.2 1.5 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 KLO08905.1 - 0.028 14.3 1.3 0.51 10.3 0.0 2.7 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 KLO08905.1 - 0.06 13.4 5.5 0.15 12.1 0.9 2.1 2 0 0 2 2 2 0 BED zinc finger ADK_lid PF05191.14 KLO08905.1 - 0.11 12.5 2.9 3.6 7.7 0.2 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_aberr PF17017.5 KLO08905.1 - 0.11 12.6 0.5 0.69 10.0 0.2 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 KLO08905.1 - 0.6 9.9 7.8 3.2 7.6 0.5 2.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain FYVE PF01363.21 KLO08905.1 - 0.89 9.7 6.7 1.9 8.7 1.8 2.1 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_6 PF13912.6 KLO08905.1 - 1.3 9.1 7.2 0.6 10.2 1.0 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger Vps51 PF08700.11 KLO08907.1 - 8.1e-24 83.5 1.2 1.1e-23 83.0 1.2 1.2 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KLO08907.1 - 0.00042 20.5 1.5 0.00061 20.0 1.5 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 KLO08907.1 - 0.00047 18.9 0.5 0.00058 18.6 0.5 1.1 1 0 0 1 1 1 1 Dor1-like family HAP1_N PF04849.13 KLO08907.1 - 0.089 12.0 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region NTP_transf_9 PF04248.12 KLO08909.1 - 5.4e-35 119.2 0.1 1.7e-26 91.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Methyltransf_2 PF00891.18 KLO08910.1 - 3.8e-24 85.2 0.0 3.1e-20 72.4 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_4 PF02390.17 KLO08910.1 - 0.0095 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KLO08910.1 - 0.011 16.4 0.0 0.077 13.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KLO08910.1 - 0.048 13.2 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain APH PF01636.23 KLO08911.1 - 1.7e-07 31.4 0.0 2.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KLO08911.1 - 0.16 11.5 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L16 PF00252.18 KLO08913.1 - 7.5e-37 126.3 0.1 9e-37 126.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PRP3 PF08572.10 KLO08914.1 - 1.9e-72 243.7 12.9 3.6e-72 242.7 12.9 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KLO08914.1 - 3.4e-41 140.8 1.7 4.8e-40 137.0 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) Pkinase_Tyr PF07714.17 KLO08915.1 - 2.4e-42 145.0 0.0 3.5e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO08915.1 - 1.4e-31 109.9 0.0 2.4e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO08915.1 - 0.0075 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KLO08915.1 - 0.021 13.9 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KLO08915.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family F-box-like PF12937.7 KLO08916.1 - 4.6e-11 42.4 0.1 1e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO08916.1 - 2.7e-05 23.9 0.0 0.00011 22.0 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KLO08916.1 - 3.2 8.3 10.6 71 4.0 0.1 6.5 7 1 1 8 8 8 0 Leucine Rich repeats (2 copies) GSHPx PF00255.19 KLO08917.1 - 1.2e-42 143.9 0.2 1.6e-42 143.5 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KLO08917.1 - 3.5e-05 23.7 0.1 0.0001 22.2 0.1 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KLO08917.1 - 0.0015 18.3 0.1 0.0037 17.0 0.1 1.7 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.6 KLO08917.1 - 0.18 12.3 0.0 0.5 10.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) zinc_ribbon_12 PF11331.8 KLO08918.1 - 0.18 11.6 10.2 0.34 10.7 10.2 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon domain Lar_restr_allev PF14354.6 KLO08919.1 - 0.011 16.1 0.4 0.026 14.9 0.3 1.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_clus PF00172.18 KLO08920.1 - 0.00093 19.3 6.7 0.0015 18.6 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec8_exocyst PF04048.14 KLO08923.1 - 0.51 10.2 10.3 0.03 14.2 3.7 2.0 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Telomerase_RBD PF12009.8 KLO08924.1 - 3e-05 24.1 0.0 3.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain TPR_2 PF07719.17 KLO08926.1 - 7.3e-06 25.7 4.1 0.079 13.1 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KLO08926.1 - 0.00085 19.4 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Clathrin PF00637.20 KLO08926.1 - 0.002 18.0 0.3 0.0055 16.6 0.1 1.8 1 1 0 2 2 2 1 Region in Clathrin and VPS TPR_7 PF13176.6 KLO08926.1 - 0.0026 17.7 0.4 21 5.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KLO08926.1 - 0.0047 17.4 0.2 0.17 12.4 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KLO08926.1 - 0.0084 16.9 0.0 1.8 9.6 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 KLO08926.1 - 0.013 15.8 2.8 0.074 13.4 0.2 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KLO08926.1 - 0.013 15.3 3.6 3 7.8 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SMG1 PF15785.5 KLO08926.1 - 0.015 13.7 2.3 0.022 13.2 1.5 1.6 1 1 1 2 2 2 0 Serine/threonine-protein kinase smg-1 TPR_8 PF13181.6 KLO08926.1 - 0.059 13.6 3.3 0.93 9.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KLO08926.1 - 0.15 12.4 0.2 5.4 7.4 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KLO08926.1 - 0.21 11.3 1.2 22 4.9 0.2 3.2 2 1 1 3 3 3 0 TPR repeat MIT PF04212.18 KLO08926.1 - 0.41 10.8 0.1 0.41 10.8 0.1 2.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Ribophorin_II PF05817.14 KLO08926.1 - 3.3 6.1 5.6 9.2 4.7 5.6 1.7 1 1 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Phosphonate-bd PF12974.7 KLO08930.1 - 1.4e-06 28.1 0.0 2.2e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 KLO08930.1 - 4.1e-05 23.6 0.2 0.00012 22.1 0.0 1.9 2 1 1 3 3 3 1 NMT1/THI5 like NMT1_3 PF16868.5 KLO08930.1 - 0.0003 20.3 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 KLO08930.1 - 0.0028 17.1 0.0 0.0094 15.4 0.0 1.9 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 LysR_substrate PF03466.20 KLO08930.1 - 0.025 13.9 0.0 0.13 11.6 0.0 1.8 1 1 0 1 1 1 0 LysR substrate binding domain Lipase_3 PF01764.25 KLO08931.1 - 2.8e-07 30.5 0.0 2.6e-06 27.3 0.0 2.1 1 1 1 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KLO08931.1 - 0.0064 17.1 1.4 0.0064 17.1 1.4 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KLO08931.1 - 0.15 11.8 0.1 0.38 10.4 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Metallophos PF00149.28 KLO08932.1 - 1.2e-07 32.5 0.0 3.7e-07 30.8 0.0 1.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 KLO08932.1 - 0.0091 14.3 0.9 0.023 13.0 0.1 1.8 2 0 0 2 2 2 1 Firmicute fructose-1,6-bisphosphatase Yip1 PF04893.17 KLO08933.1 - 3.8e-14 52.8 16.7 5.5e-14 52.2 16.7 1.3 1 0 0 1 1 1 1 Yip1 domain ATG22 PF11700.8 KLO08934.1 - 1.6e-122 409.6 21.9 1.8e-122 409.4 21.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF2456 PF10445.9 KLO08934.1 - 3.5 7.8 12.3 2.7 8.1 7.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) Trehalase PF01204.18 KLO08935.1 - 4.5e-160 533.8 0.0 5.5e-160 533.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KLO08935.1 - 1.1e-11 44.3 0.0 1.9e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RHH_4 PF13467.6 KLO08935.1 - 0.022 14.6 0.0 9.2 6.2 0.0 2.8 3 0 0 3 3 3 0 Ribbon-helix-helix domain Nucleoporin_FG PF13634.6 KLO08936.1 - 2.2e-10 41.3 84.9 1.8e-07 31.9 32.1 3.6 1 1 2 3 3 3 3 Nucleoporin FG repeat region Nucleoporin_FG2 PF15967.5 KLO08936.1 - 1.6e-05 23.7 34.2 7.3e-05 21.5 34.2 2.1 1 1 0 1 1 1 1 Nucleoporin FG repeated region AIP3 PF03915.13 KLO08936.1 - 0.014 14.5 6.7 0.038 13.1 6.7 1.6 1 1 0 1 1 1 0 Actin interacting protein 3 SKA2 PF16740.5 KLO08936.1 - 0.018 14.9 5.5 0.27 11.0 0.7 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 FapA PF03961.13 KLO08936.1 - 0.075 11.6 1.5 4.4 5.8 1.1 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF1690 PF07956.11 KLO08936.1 - 0.97 9.8 6.8 0.84 10.0 0.2 2.4 2 1 0 2 2 2 0 Protein of Unknown function (DUF1690) Fib_alpha PF08702.10 KLO08936.1 - 1 9.6 4.9 32 4.7 0.2 3.3 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Arrestin_N PF00339.29 KLO08937.1 - 2.1e-08 34.4 0.1 1.6e-05 25.0 0.0 3.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DUF3704 PF12488.8 KLO08937.1 - 0.36 10.5 0.1 0.36 10.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3704) Arrestin_N PF00339.29 KLO08938.1 - 3e-06 27.3 0.0 0.038 14.0 0.0 3.2 3 1 1 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Actin PF00022.19 KLO08939.1 - 1.2e-41 142.7 0.0 2.9e-36 125.0 0.0 3.1 2 1 0 2 2 2 2 Actin DUF5542 PF17696.1 KLO08941.1 - 2.3 8.4 7.1 19 5.4 0.1 3.2 4 0 0 4 4 4 0 Family of unknown function (DUF5542) DctQ PF04290.12 KLO08943.1 - 0.0057 16.6 3.5 0.0057 16.6 3.5 2.2 3 0 0 3 3 3 1 Tripartite ATP-independent periplasmic transporters, DctQ component APAF1_C PF17908.1 KLO08943.1 - 0.053 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 APAF-1 helical domain PHD PF00628.29 KLO08947.1 - 1.9e-07 30.8 5.2 4.9e-07 29.5 5.2 1.7 1 1 0 1 1 1 1 PHD-finger Zf_RING PF16744.5 KLO08947.1 - 1.8e-06 27.9 4.0 4.5e-06 26.7 4.0 1.6 1 0 0 1 1 1 1 KIAA1045 RING finger C1_1 PF00130.22 KLO08947.1 - 0.027 14.3 9.9 0.093 12.6 4.8 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 KLO08947.1 - 0.087 12.4 3.6 0.25 11.0 3.2 1.9 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KLO08947.1 - 0.097 12.3 2.5 0.63 9.7 0.1 2.4 2 0 0 2 2 2 0 PHD-finger Lipase_GDSL_2 PF13472.6 KLO08948.1 - 4e-06 27.4 0.4 1.1e-05 26.0 0.4 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KLO08948.1 - 8.4e-06 25.9 0.0 1.6e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 KLO08949.1 - 2.8e-22 79.1 37.6 1.6e-15 56.9 21.9 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KLO08949.1 - 1.1e-06 27.8 0.4 0.064 12.1 0.4 4.2 2 1 2 4 4 4 2 MFS_1 like family Sugar_tr PF00083.24 KLO08949.1 - 0.0034 16.3 3.9 0.0034 16.3 3.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KLO08949.1 - 0.23 9.7 3.4 0.29 9.4 1.2 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family OTU PF02338.19 KLO08950.1 - 0.0024 18.4 0.0 0.0042 17.6 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-met PF12874.7 KLO08950.1 - 0.03 14.7 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KLO08950.1 - 0.16 12.3 0.1 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding UN_NPL4 PF11543.8 KLO08950.1 - 0.16 12.5 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 p450 PF00067.22 KLO08951.1 - 1.5e-63 215.2 0.0 2.3e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Tom37 PF10568.9 KLO08952.1 - 1.5e-29 102.9 0.1 5.8e-29 100.9 0.0 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KLO08952.1 - 3.8e-14 52.2 0.2 8.2e-14 51.1 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KLO08952.1 - 8.4e-09 36.1 0.0 1.7e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KLO08952.1 - 3.5e-07 30.1 0.0 2.4e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RNA_pol_3_Rpc31 PF11705.8 KLO08952.1 - 0.029 14.7 4.5 0.053 13.8 4.5 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GST_C PF00043.25 KLO08952.1 - 0.042 14.1 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GYF PF02213.16 KLO08953.1 - 6e-05 22.6 2.0 6.6e-05 22.5 0.4 2.0 2 0 0 2 2 2 1 GYF domain DUF1465 PF07323.12 KLO08953.1 - 0.099 12.5 3.7 0.18 11.7 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Rsd_AlgQ PF04353.13 KLO08953.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Ydc2-catalyt PF09159.10 KLO08953.1 - 0.27 10.9 6.7 0.058 13.1 3.0 1.6 2 0 0 2 2 2 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SNF2_N PF00176.23 KLO08954.1 - 3.2e-56 190.6 0.0 4.5e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KLO08954.1 - 1.2e-43 149.4 9.0 2.4e-43 148.4 9.0 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 KLO08954.1 - 4.4e-16 59.2 0.0 9.9e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO08954.1 - 1.6e-08 34.7 0.0 4e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KLO08954.1 - 1e-07 31.4 0.2 5.1e-07 29.2 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KLO08954.1 - 1e-05 24.9 0.0 2.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PEP_mutase PF13714.6 KLO08956.1 - 9e-43 146.4 2.3 1.1e-42 146.1 2.3 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KLO08956.1 - 2.2e-17 62.8 0.2 3e-17 62.3 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PEP_hydrolase PF09370.10 KLO08956.1 - 0.042 13.1 0.0 0.091 12.0 0.0 1.6 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Snf7 PF03357.21 KLO08957.1 - 3e-21 75.8 4.5 4.3e-21 75.3 4.5 1.2 1 0 0 1 1 1 1 Snf7 HlyD_2 PF12700.7 KLO08957.1 - 0.0063 15.3 0.7 0.0085 14.9 0.7 1.1 1 0 0 1 1 1 1 HlyD family secretion protein FlaC_arch PF05377.11 KLO08957.1 - 0.29 11.6 2.8 39 4.7 0.0 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) PHD PF00628.29 KLO08959.1 - 1.5e-07 31.2 5.2 3.4e-07 30.0 5.2 1.6 1 1 0 1 1 1 1 PHD-finger Zf_RING PF16744.5 KLO08959.1 - 0.00077 19.5 5.1 0.0024 17.9 5.1 1.8 1 1 0 1 1 1 1 KIAA1045 RING finger C1_1 PF00130.22 KLO08959.1 - 0.014 15.3 3.6 0.014 15.3 3.6 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SBP_bac_11 PF13531.6 KLO08959.1 - 0.018 14.8 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein zf-PHD-like PF15446.6 KLO08959.1 - 0.021 14.5 1.3 0.021 14.5 1.3 1.8 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 KLO08959.1 - 5.1 7.5 10.9 1.3 9.4 6.3 2.1 2 0 0 2 2 2 0 C1 domain Methyltransf_2 PF00891.18 KLO08961.1 - 3.4e-16 59.2 0.0 2.2e-15 56.5 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KLO08961.1 - 0.039 14.7 0.0 0.087 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FHA PF00498.26 KLO08962.1 - 1.6e-15 57.2 1.8 1.9e-15 57.0 0.0 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KLO08962.1 - 0.0014 18.9 0.0 0.014 15.6 0.0 2.6 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF948 PF06103.11 KLO08962.1 - 1.5 9.1 11.3 5.7 7.3 0.6 4.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1878 PF08963.10 KLO08962.1 - 8.9 6.9 11.0 5.9 7.4 2.7 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1878) BLOC1_2 PF10046.9 KLO08962.1 - 9.7 6.6 17.5 0.12 12.6 0.4 3.7 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAD_binding_7 PF03441.14 KLO08963.1 - 3.8e-43 147.3 1.9 6.2e-43 146.6 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KLO08963.1 - 4.3e-22 78.9 0.0 8.7e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase WRNPLPNID PF15017.6 KLO08964.1 - 0.022 15.6 1.1 0.23 12.4 0.5 2.0 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box YjbH PF06082.11 KLO08965.1 - 2.4 6.8 3.8 3.9 6.2 3.8 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH UCH PF00443.29 KLO08966.1 - 1.8e-32 112.8 2.6 7e-32 110.9 2.6 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KLO08966.1 - 7.3e-19 68.5 2.9 1.9e-17 63.9 2.9 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KLO08966.1 - 2e-10 40.2 0.1 5.3e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 KLO08966.1 - 1.5e-07 31.9 0.0 0.00045 20.8 0.0 4.1 4 0 0 4 4 4 1 DUSP domain zf-RanBP PF00641.18 KLO08966.1 - 0.013 14.8 1.3 0.013 14.8 1.3 2.8 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Ubiquitin_4 PF18036.1 KLO08966.1 - 0.037 14.1 0.4 2 8.5 0.1 2.9 1 1 1 2 2 2 0 Ubiquitin-like domain Rad60-SLD PF11976.8 KLO08966.1 - 0.11 12.3 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2757 PF10955.8 KLO08966.1 - 5.8 7.2 7.4 0.83 10.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) Gaa1 PF04114.14 KLO08967.1 - 2.9e-106 356.5 2.0 1.1e-104 351.3 2.0 2.1 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF4381 PF14316.6 KLO08968.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) WD40 PF00400.32 KLO08972.1 - 9.1e-40 133.9 9.8 1.2e-10 41.8 0.0 6.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO08972.1 - 2.7e-12 46.8 0.5 0.013 15.8 0.0 5.3 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KLO08972.1 - 2.8e-08 33.9 0.0 2.7e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 NACHT domain Ge1_WD40 PF16529.5 KLO08972.1 - 4.9e-06 25.7 0.1 0.58 9.1 0.0 3.5 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA PF00004.29 KLO08972.1 - 1.9e-05 25.1 0.0 0.00037 20.9 0.1 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO08972.1 - 4.8e-05 23.6 0.0 0.00016 21.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KLO08972.1 - 0.00014 22.3 0.0 0.00096 19.6 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain PD40 PF07676.12 KLO08972.1 - 0.0015 18.4 0.1 14 5.7 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Zeta_toxin PF06414.12 KLO08972.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KLO08972.1 - 0.026 13.7 0.0 0.059 12.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Nup160 PF11715.8 KLO08972.1 - 0.026 13.2 0.8 8 5.0 0.0 3.5 3 1 0 4 4 4 0 Nucleoporin Nup120/160 Gmad1 PF10647.9 KLO08972.1 - 0.035 13.9 0.3 0.2 11.4 0.2 2.1 1 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain RNA_helicase PF00910.22 KLO08972.1 - 0.036 14.5 0.1 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 KLO08972.1 - 0.073 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 KLO08972.1 - 0.17 11.4 0.0 24 4.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF5122 PF17164.4 KLO08972.1 - 0.74 10.1 4.7 2.5 8.5 0.1 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF5122) beta-propeller F-box-like PF12937.7 KLO08976.1 - 9.2e-07 28.7 0.1 2.1e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO08976.1 - 0.24 11.9 2.4 9.1 6.9 0.0 4.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO08977.1 - 9.6e-05 22.2 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO08977.1 - 0.55 10.7 12.7 13 6.4 0.7 6.1 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Phosphodiest PF01663.22 KLO08978.1 - 1.9e-78 264.5 1.4 2.4e-78 264.2 1.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Pkinase PF00069.25 KLO08979.1 - 6.1e-24 84.8 0.0 2.1e-23 83.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO08979.1 - 4.7e-10 39.2 0.0 7e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO08979.1 - 0.044 13.7 0.1 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family PIN_6 PF17146.4 KLO08979.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 PIN domain of ribonuclease DPPIV_N PF00930.21 KLO08979.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region adh_short PF00106.25 KLO08980.1 - 8.1e-31 107.0 0.0 1.5e-25 89.8 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KLO08980.1 - 9.5e-18 64.6 0.0 4.7e-14 52.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO08980.1 - 9e-08 32.2 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO08980.1 - 1.2e-06 28.2 0.0 2.3e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO08980.1 - 0.13 11.7 0.1 0.31 10.4 0.1 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KLO08980.1 - 0.13 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KLO08981.1 - 1.5e-28 99.6 0.0 1.1e-23 83.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KLO08981.1 - 9.6e-18 64.6 0.0 2.8e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO08981.1 - 3e-07 30.5 0.3 7.4e-07 29.3 0.3 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO08981.1 - 7.5e-05 22.3 0.0 0.00084 18.9 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO08981.1 - 0.0012 18.4 0.0 0.0085 15.5 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KLO08981.1 - 0.033 13.3 0.1 0.047 12.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KLO08981.1 - 0.035 14.4 0.1 0.074 13.3 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AAA_22 PF13401.6 KLO08981.1 - 0.067 13.5 0.0 4.1 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain adh_short PF00106.25 KLO08982.1 - 3e-30 105.1 0.0 3.1e-25 88.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KLO08982.1 - 3.3e-19 69.4 0.0 3e-16 59.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO08982.1 - 1.2e-09 38.3 0.1 1.9e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO08982.1 - 0.00036 20.1 0.1 0.00042 19.9 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO08982.1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KLO08982.1 - 0.012 15.9 0.1 0.026 14.8 0.1 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KLO08982.1 - 0.015 14.4 0.1 0.019 14.1 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KLO08983.1 - 4.9e-28 97.9 0.0 3e-24 85.6 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KLO08983.1 - 3.4e-16 59.5 0.0 1.9e-14 53.8 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO08983.1 - 5.3e-09 36.2 0.0 8.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO08983.1 - 0.0002 20.9 0.0 0.0013 18.3 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO08983.1 - 0.0014 18.1 0.0 0.0026 17.2 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KLO08983.1 - 0.024 13.8 0.1 0.035 13.3 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Luciferase_cat PF10285.9 KLO08983.1 - 0.06 12.7 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain Sacchrp_dh_NADP PF03435.18 KLO08983.1 - 0.068 13.4 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain QRPTase_C PF01729.19 KLO08983.1 - 0.073 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DHQS PF01959.16 KLO08983.1 - 0.089 11.7 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase II DPBB_1 PF03330.18 KLO08985.1 - 4e-05 23.8 0.5 0.001 19.3 0.1 2.9 1 1 1 2 2 2 1 Lytic transglycolase Nucleoporin_FG2 PF15967.5 KLO08985.1 - 0.053 12.1 3.2 0.058 11.9 3.2 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region DUF3421 PF11901.8 KLO08987.1 - 0.0085 16.1 0.0 0.13 12.3 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3421) Nop25 PF09805.9 KLO08987.1 - 0.98 9.9 0.0 0.98 9.9 0.0 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) MFS_1 PF07690.16 KLO08989.1 - 1.3e-32 113.1 27.4 1.9e-32 112.6 27.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO08989.1 - 3.7e-32 111.8 21.9 8.2e-32 110.6 21.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter GNAT_acetyltr_2 PF13718.6 KLO08990.1 - 8.1e-93 310.0 0.0 1.6e-92 309.0 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KLO08990.1 - 2.5e-79 266.3 1.5 3.8e-79 265.7 1.5 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KLO08990.1 - 1.7e-64 216.9 0.0 6.3e-64 215.1 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KLO08990.1 - 1.2e-32 111.6 0.7 2.5e-32 110.7 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KLO08990.1 - 0.0034 17.1 1.8 0.065 12.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KLO08990.1 - 0.0048 17.2 0.0 0.1 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain CoA_binding_2 PF13380.6 KLO08991.1 - 5.5e-23 81.7 0.0 9e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KLO08991.1 - 8.5e-05 23.2 0.0 0.00021 21.9 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain PRD1_DD PF11087.8 KLO08991.1 - 0.069 12.8 0.7 4.7 7.0 0.0 2.7 3 0 0 3 3 3 0 PRD1 phage membrane DNA delivery Pex24p PF06398.11 KLO08992.1 - 5.2e-31 107.9 10.3 9.7e-31 107.1 10.3 1.4 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin adh_short PF00106.25 KLO08994.1 - 2.4e-33 115.2 0.9 1.6e-28 99.5 0.3 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KLO08994.1 - 2.2e-21 76.5 0.3 2.5e-17 63.2 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KLO08994.1 - 9.2e-10 38.4 0.4 2.5e-09 36.9 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KLO08994.1 - 2.1e-09 37.5 0.4 4e-09 36.6 0.4 1.5 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KLO08994.1 - 6e-07 29.2 0.3 0.00067 19.2 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KLO08994.1 - 0.00034 19.9 1.0 0.0019 17.4 1.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KLO08994.1 - 0.0019 18.1 1.2 0.006 16.5 0.3 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KLO08994.1 - 0.0027 18.0 0.1 0.0057 16.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain QRPTase_C PF01729.19 KLO08994.1 - 0.0059 16.4 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain THF_DHG_CYH_C PF02882.19 KLO08994.1 - 0.082 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Tfb4 PF03850.14 KLO08994.1 - 0.16 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF4601 PF15373.6 KLO08994.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) adh_short PF00106.25 KLO08995.1 - 3.9e-33 114.5 0.0 7.8e-26 90.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KLO08995.1 - 1.1e-21 77.5 0.0 6.6e-19 68.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO08995.1 - 3.8e-09 36.7 0.0 5.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO08995.1 - 1.2e-05 24.9 0.1 2e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KLO08995.1 - 0.00052 19.3 0.0 0.0008 18.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KLO08995.1 - 0.0013 18.2 0.1 0.0026 17.2 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KLO08995.1 - 0.0051 16.7 0.4 0.0088 16.0 0.4 1.6 1 1 0 1 1 1 1 NAD(P)H-binding SBP_bac_3 PF00497.20 KLO08995.1 - 0.028 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 GATase_7 PF13537.6 KLO08995.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_binding_4 PF07993.12 KLO08995.1 - 0.15 11.2 0.1 0.38 9.9 0.1 1.8 1 1 0 1 1 1 0 Male sterility protein TPR_10 PF13374.6 KLO08996.1 - 2.8e-29 100.1 25.3 2.1e-05 24.2 0.4 7.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 KLO08996.1 - 8.5e-15 54.8 24.8 0.034 14.4 2.3 7.3 3 2 3 6 6 6 5 Tetratricopeptide repeat ANAPC5 PF12862.7 KLO08996.1 - 3.6e-12 46.2 22.0 1.3 9.2 0.1 8.3 2 1 6 8 8 8 7 Anaphase-promoting complex subunit 5 TPR_8 PF13181.6 KLO08996.1 - 2.4e-09 36.7 2.5 0.26 11.6 0.1 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat AAA_16 PF13191.6 KLO08996.1 - 3.2e-08 34.1 0.0 3.2e-08 34.1 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain DUF3856 PF12968.7 KLO08996.1 - 3.5e-07 30.4 14.9 0.0054 16.8 1.6 3.8 1 1 2 3 3 3 3 Domain of Unknown Function (DUF3856) TPR_2 PF07719.17 KLO08996.1 - 4e-06 26.5 4.6 10 6.5 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat NPV_P10 PF05531.12 KLO08996.1 - 0.00081 19.8 0.8 0.27 11.7 0.3 3.6 3 0 0 3 3 2 1 Nucleopolyhedrovirus P10 protein NACHT PF05729.12 KLO08996.1 - 0.0016 18.4 0.0 0.0048 16.8 0.0 1.8 1 1 0 1 1 1 1 NACHT domain NitrOD5 PF11537.8 KLO08996.1 - 0.014 15.5 0.4 17 5.6 0.0 4.8 2 1 4 6 6 5 0 Nitrosopumilus output domain 5 AAA PF00004.29 KLO08996.1 - 0.015 15.7 0.0 0.044 14.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rapsyn_N PF10579.9 KLO08996.1 - 0.024 14.8 0.1 32 4.7 0.0 4.3 4 1 1 5 5 5 0 Rapsyn N-terminal myristoylation and linker region AAA_22 PF13401.6 KLO08996.1 - 0.053 13.8 0.0 0.27 11.5 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 KLO08996.1 - 0.055 14.0 0.0 0.23 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KLO08996.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 KLO08996.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NTPase WASH_WAHD PF11945.8 KLO08996.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 WAHD domain of WASH complex Snapin_Pallidin PF14712.6 KLO08996.1 - 0.16 12.4 1.7 2.9 8.4 0.4 3.3 2 0 0 2 2 2 0 Snapin/Pallidin COG2 PF06148.11 KLO08996.1 - 0.52 10.4 3.3 13 5.9 0.3 3.4 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HR1 PF02185.16 KLO08996.1 - 0.53 10.4 4.1 5.6 7.2 0.1 3.7 3 0 0 3 3 3 0 Hr1 repeat DUF3584 PF12128.8 KLO08996.1 - 2 5.8 11.5 0.09 10.3 1.2 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3584) DUF2783 PF10932.8 KLO08996.1 - 2.5 7.9 8.9 12 5.6 0.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2783) TPR_7 PF13176.6 KLO08996.1 - 6.3 7.1 9.9 5.7 7.2 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF241 PF03087.14 KLO08997.1 - 0.0019 18.1 0.1 0.002 18.0 0.1 1.0 1 0 0 1 1 1 1 Arabidopsis protein of unknown function CDO_I PF05995.12 KLO08997.1 - 0.091 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Cysteine dioxygenase type I MEF2_binding PF09047.10 KLO08997.1 - 0.16 11.8 0.6 0.27 11.1 0.6 1.4 1 0 0 1 1 1 0 MEF2 binding CENP-B_dimeris PF09026.10 KLO09000.1 - 0.13 12.7 8.3 0.17 12.3 8.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RRN3 PF05327.11 KLO09000.1 - 0.21 10.1 0.7 0.23 10.0 0.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 KLO09000.1 - 0.76 7.8 5.8 0.89 7.6 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KLO09000.1 - 1.8 7.6 11.4 2.2 7.3 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 KLO09000.1 - 2.3 7.4 9.8 3.2 7.0 9.8 1.1 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.16 KLO09001.1 - 2.5e-18 66.2 50.1 8.5e-11 41.4 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_10 PF05176.14 KLO09002.1 - 1.3e-55 188.5 0.0 1.6e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein MFS_1 PF07690.16 KLO09003.1 - 1.7e-21 76.5 52.4 9e-13 47.9 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HLH PF00010.26 KLO09004.1 - 5.6e-10 39.0 0.0 3.7e-09 36.4 0.0 2.4 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain TPT PF03151.16 KLO09005.1 - 6.4e-20 71.7 15.9 8.2e-20 71.3 15.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KLO09005.1 - 0.00062 19.9 28.4 0.015 15.5 13.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family DUF563 PF04577.14 KLO09006.1 - 5.6e-08 33.2 0.0 1.4e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) adh_short PF00106.25 KLO09007.1 - 1e-39 136.1 0.1 1.4e-39 135.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO09007.1 - 1.2e-28 100.3 0.0 1.8e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO09007.1 - 0.00016 21.7 0.1 0.00024 21.1 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KLO09007.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DUF1776 PF08643.10 KLO09007.1 - 0.08 12.3 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FAA_hydrolase_N PF09298.11 KLO09007.1 - 0.17 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal adh_short PF00106.25 KLO09008.1 - 1.7e-37 128.8 0.3 2.3e-37 128.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO09008.1 - 7.3e-23 81.3 0.2 1e-22 80.9 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO09008.1 - 1.9e-05 24.7 0.2 3e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 KR domain RNA_pol_L_2 PF13656.6 KLO09009.1 - 1.1e-21 76.4 0.0 1.6e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KLO09009.1 - 3.4e-11 42.4 0.0 5.8e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L27A PF00828.19 KLO09010.1 - 4.9e-21 75.7 0.0 7.4e-21 75.1 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RRM_1 PF00076.22 KLO09011.1 - 2.8e-10 39.9 0.0 4.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 KLO09011.1 - 0.11 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Smg-4/UPF3 family FoP_duplication PF13865.6 KLO09011.1 - 0.11 13.1 0.1 0.11 13.1 0.1 1.9 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 CobN-Mg_chel PF02514.16 KLO09012.1 - 0.12 10.0 0.0 0.16 9.7 0.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase PH PF00169.29 KLO09013.1 - 0.00039 20.9 0.0 0.00071 20.1 0.0 1.4 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 KLO09013.1 - 0.00097 19.5 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1110 PF06533.12 KLO09013.1 - 0.026 14.5 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) Metallophos PF00149.28 KLO09015.1 - 3.2e-40 138.8 0.1 4.3e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KLO09015.1 - 9.8e-22 77.1 0.5 2.1e-21 76.1 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain CBM_1 PF00734.18 KLO09016.1 - 8.7e-12 44.8 17.1 2.9e-11 43.1 17.1 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Sec23_trunk PF04811.15 KLO09017.1 - 1.8e-71 240.6 0.0 2.6e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KLO09017.1 - 2.3e-28 98.7 0.0 4.2e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KLO09017.1 - 1.9e-24 85.5 0.1 3.9e-24 84.4 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KLO09017.1 - 3.8e-14 52.4 0.0 2.3e-13 49.8 0.0 2.3 2 0 0 2 2 2 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KLO09017.1 - 3.7e-13 49.3 6.9 7.7e-13 48.3 6.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Phage_lysis PF03245.13 KLO09017.1 - 0.48 10.6 1.4 2.5 8.3 0.1 2.4 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein Helicase_C PF00271.31 KLO09018.1 - 3.2e-16 59.6 0.0 2.1e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO09018.1 - 5.9e-14 52.2 0.0 9e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO09018.1 - 1.2e-07 31.9 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 KLO09018.1 - 0.017 15.8 0.6 0.047 14.4 0.0 2.1 2 0 0 2 2 2 0 RecQ zinc-binding Ribosomal_L12_N PF16320.5 KLO09018.1 - 0.34 10.6 1.1 5 6.9 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain MFS_1 PF07690.16 KLO09022.1 - 1.7e-21 76.5 40.8 1.6e-14 53.6 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SKG6 PF08693.10 KLO09023.1 - 0.0016 17.8 1.9 0.0037 16.7 1.9 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KLO09023.1 - 0.013 16.4 0.0 0.024 15.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 KLO09023.1 - 0.073 13.3 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Beta-APP PF03494.13 KLO09023.1 - 8.7 6.3 10.0 23 5.0 9.4 1.9 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) Ribophorin_II PF05817.14 KLO09025.1 - 1.2e-30 106.7 0.4 4.8e-30 104.7 0.4 1.7 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF2583 PF10762.9 KLO09025.1 - 2.2 8.8 4.3 2 8.9 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) Glyco_hydro_47 PF01532.20 KLO09026.1 - 3.1e-124 415.3 0.0 3.6e-124 415.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Histone PF00125.24 KLO09027.1 - 1.3e-23 83.8 2.1 1.7e-23 83.4 2.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KLO09027.1 - 6.2e-06 26.4 0.1 6.2e-06 26.4 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KLO09027.1 - 0.00032 21.1 0.0 0.00052 20.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KLO09027.1 - 0.0017 18.4 0.2 0.0021 18.1 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein Bt_P21 PF05560.11 KLO09027.1 - 0.074 12.6 0.1 0.094 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Histone_H2A_C PF16211.5 KLO09028.1 - 6e-17 61.1 0.7 1e-16 60.3 0.7 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KLO09028.1 - 1.7e-15 57.6 0.0 2.2e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KLO09028.1 - 1.1e-05 25.6 0.0 1.8e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.25 KLO09029.1 - 2.1e-54 184.7 0.0 2.8e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO09029.1 - 2.5e-39 135.1 0.0 3.4e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO09029.1 - 8.6e-10 38.4 0.0 1.6e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KLO09029.1 - 0.0025 17.2 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Oxidored_FMN PF00724.20 KLO09030.1 - 1.7e-65 221.6 0.0 2.1e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1611_N PF17396.2 KLO09030.1 - 0.045 14.0 0.2 5.8 7.2 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain F-box-like PF12937.7 KLO09032.1 - 2.6e-07 30.4 1.9 2.9e-07 30.3 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO09032.1 - 0.00083 19.2 0.0 0.0025 17.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO09033.1 - 6.4e-08 32.4 0.1 1.8e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09033.1 - 0.0036 17.1 0.1 0.012 15.5 0.1 2.0 1 0 0 1 1 1 1 F-box domain B_lectin PF01453.24 KLO09034.1 - 0.076 13.6 0.0 0.14 12.7 0.0 1.3 1 1 0 1 1 1 0 D-mannose binding lectin DUF3421 PF11901.8 KLO09035.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3421) Aldo_ket_red PF00248.21 KLO09036.1 - 3e-65 220.3 0.0 3.8e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Acyl-CoA_dh_M PF02770.19 KLO09037.1 - 0.015 15.5 0.0 0.089 13.0 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_M PF02770.19 KLO09038.1 - 0.0082 16.3 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Pkinase_Tyr PF07714.17 KLO09040.1 - 3.3e-29 102.0 0.0 4.6e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO09040.1 - 2.2e-26 92.8 0.0 2.8e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO09040.1 - 0.0042 17.0 0.0 0.019 14.9 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO09040.1 - 0.036 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KLO09040.1 - 0.057 12.8 0.7 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KLO09040.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NmrA PF05368.13 KLO09041.1 - 6.7e-57 192.7 0.0 8.6e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO09041.1 - 2.1e-17 63.6 0.0 3.1e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KLO09041.1 - 7.4e-07 28.9 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO09041.1 - 2e-05 23.7 0.0 3.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KLO09041.1 - 0.0004 20.3 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KLO09041.1 - 0.031 14.6 0.1 0.065 13.5 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KLO09041.1 - 0.052 12.9 0.1 0.081 12.3 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KLO09041.1 - 0.071 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.24 KLO09041.1 - 0.12 12.8 0.1 0.26 11.7 0.1 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 5_3_exonuc_N PF02739.16 KLO09042.1 - 0.009 15.9 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain TGT PF01702.18 KLO09047.1 - 0.058 12.5 0.0 0.058 12.5 0.0 1.0 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase HTH_32 PF13565.6 KLO09048.1 - 5.6e-07 30.1 0.0 8.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 KLO09048.1 - 1.7e-06 27.6 0.8 0.0007 19.3 0.0 2.7 3 0 0 3 3 3 2 Homeodomain-like domain HTH_33 PF13592.6 KLO09048.1 - 1.1e-05 25.0 0.0 2.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KLO09048.1 - 9.4e-05 22.6 0.1 0.0003 21.0 0.0 1.8 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.6 KLO09048.1 - 0.00026 21.0 1.5 0.0044 17.0 0.0 2.7 2 1 1 3 3 3 1 Winged helix-turn helix TrmB PF01978.19 KLO09048.1 - 0.00097 19.0 0.0 0.0052 16.7 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Tnp_ISL3 PF13542.6 KLO09048.1 - 0.0024 17.2 0.7 2.1 7.8 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 LacI PF00356.21 KLO09048.1 - 0.24 11.2 0.5 3 7.7 0.0 2.4 2 1 0 2 2 2 0 Bacterial regulatory proteins, lacI family AT_hook PF02178.19 KLO09049.1 - 0.031 14.1 6.2 0.2 11.6 6.2 2.6 1 0 0 1 1 1 0 AT hook motif DUF4147 PF13660.6 KLO09050.1 - 0.031 13.8 0.0 0.45 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) DUF3421 PF11901.8 KLO09051.1 - 0.18 11.8 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3421) F-box-like PF12937.7 KLO09052.1 - 0.0011 18.8 0.8 0.0023 17.8 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09052.1 - 0.0076 16.1 0.9 0.025 14.4 0.9 2.0 1 0 0 1 1 1 1 F-box domain Pkinase_Tyr PF07714.17 KLO09054.1 - 2.9e-08 33.3 0.6 4.3e-07 29.5 0.5 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO09054.1 - 4.2e-07 29.6 0.9 7e-06 25.6 0.8 2.4 1 1 0 1 1 1 1 Protein kinase domain HEPN_Swt1 PF18731.1 KLO09054.1 - 0.055 13.8 0.9 0.12 12.7 0.9 1.5 1 0 0 1 1 1 0 Swt1-like HEPN RIO1 PF01163.22 KLO09054.1 - 0.099 12.2 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Myb_DNA-bind_3 PF12776.7 KLO09055.1 - 9.6e-10 39.3 0.2 0.00011 23.1 0.0 2.1 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KLO09055.1 - 0.00081 19.7 0.3 0.0037 17.6 0.2 2.0 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 KLO09057.1 - 8.3e-07 28.8 0.1 1.2e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KLO09057.1 - 0.00026 20.6 0.0 0.00034 20.3 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 KLO09057.1 - 0.0008 19.7 0.1 0.0015 18.9 0.1 1.4 1 0 0 1 1 1 1 Transposase DDE domain HTH_23 PF13384.6 KLO09058.1 - 0.036 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 KLO09058.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase_Tyr PF07714.17 KLO09059.1 - 7.9e-26 90.9 0.0 9.5e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO09059.1 - 1.1e-23 83.9 0.0 1.3e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO09059.1 - 0.03 14.3 0.0 0.057 13.3 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KLO09059.1 - 0.047 13.1 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PNKP-ligase_C PF16536.5 KLO09059.1 - 0.087 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, C-terminal region PilN PF05137.13 KLO09060.1 - 0.14 12.3 0.0 17 5.6 0.0 2.7 3 0 0 3 3 3 0 Fimbrial assembly protein (PilN) Mit_KHE1 PF10173.9 KLO09062.1 - 4.5e-53 180.2 0.0 6e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Piwi PF02171.17 KLO09063.1 - 2e-76 257.1 0.0 2.9e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KLO09063.1 - 2.1e-11 44.6 0.0 5.3e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KLO09063.1 - 0.0009 18.9 0.1 0.0021 17.7 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PSD5 PF07637.11 KLO09063.1 - 0.003 17.8 0.0 0.0081 16.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1595) ArgoMid PF16487.5 KLO09063.1 - 0.03 14.6 0.0 0.086 13.1 0.0 1.8 1 0 0 1 1 1 0 Mid domain of argonaute ArgoL2 PF16488.5 KLO09063.1 - 0.033 14.5 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 Argonaute linker 2 domain SOG2 PF10428.9 KLO09064.1 - 1.9 7.6 4.6 2 7.5 4.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PhyH PF05721.13 KLO09065.1 - 5.1e-05 23.6 0.1 0.0029 17.9 0.0 2.4 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Adeno_E3_CR2 PF02439.15 KLO09066.1 - 0.19 11.5 0.4 0.32 10.8 0.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FAM176 PF14851.6 KLO09066.1 - 0.28 10.8 2.4 1 9.0 1.0 2.3 2 0 0 2 2 2 0 FAM176 family Utp14 PF04615.13 KLO09066.1 - 0.96 7.9 4.0 1.6 7.2 4.0 1.2 1 0 0 1 1 1 0 Utp14 protein TMEM154 PF15102.6 KLO09066.1 - 2.7 7.9 4.7 0.87 9.5 0.1 2.4 2 0 0 2 2 2 0 TMEM154 protein family E1_dh PF00676.20 KLO09067.1 - 1.5e-88 296.6 0.0 1.8e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component CRISPR_Cse1 PF09481.10 KLO09068.1 - 0.076 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) Peptidase_C48 PF02902.19 KLO09070.1 - 2.4e-07 30.8 0.1 2.8e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain OrfB_Zn_ribbon PF07282.11 KLO09071.1 - 0.18 11.8 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain COesterase PF00135.28 KLO09072.1 - 1.7e-88 297.7 0.0 2.3e-88 297.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family PRKG1_interact PF15898.5 KLO09073.1 - 0.009 16.9 2.3 1.7 9.6 0.0 3.4 3 0 0 3 3 3 1 cGMP-dependent protein kinase interacting domain SKN1 PF03935.15 KLO09074.1 - 6.4e-204 678.0 7.3 7.4e-204 677.8 7.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Baculo_19 PF04798.12 KLO09075.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Baculovirus 19 kDa protein conserved region Ribosomal_S24e PF01282.19 KLO09075.1 - 0.1 12.6 0.7 0.19 11.7 0.1 1.8 2 1 0 2 2 2 0 Ribosomal protein S24e DUF3682 PF12446.8 KLO09080.1 - 1.7 9.2 8.0 0.42 11.1 5.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) TANGO2 PF05742.12 KLO09081.1 - 0.024 14.7 3.0 2.8 7.9 0.1 2.3 2 0 0 2 2 2 0 Transport and Golgi organisation 2 Prominin PF05478.11 KLO09081.1 - 0.062 11.2 4.3 0.11 10.4 4.3 1.3 1 0 0 1 1 1 0 Prominin Fib_alpha PF08702.10 KLO09081.1 - 0.27 11.4 11.0 12 6.1 8.1 3.5 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Phasin PF05597.11 KLO09081.1 - 0.53 10.3 4.9 1.6 8.8 2.4 2.9 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 KLO09081.1 - 0.77 9.8 6.6 0.47 10.5 2.7 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4404 PF14357.6 KLO09081.1 - 2.8 8.7 12.6 3.6 8.3 1.2 4.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) FAM76 PF16046.5 KLO09081.1 - 5.1 6.4 10.3 0.84 8.9 6.1 1.8 2 0 0 2 2 2 0 FAM76 protein RecG_N PF17190.4 KLO09081.1 - 8.5 7.2 9.5 7.4 7.4 0.3 3.3 3 1 1 4 4 4 0 RecG N-terminal helical domain DUF1640 PF07798.11 KLO09082.1 - 0.026 14.6 6.4 0.14 12.2 6.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Cnn_1N PF07989.11 KLO09082.1 - 0.064 13.4 0.4 0.064 13.4 0.4 2.3 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Ax_dynein_light PF10211.9 KLO09082.1 - 0.2 11.6 11.1 1.2 9.1 1.1 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain Uso1_p115_C PF04871.13 KLO09082.1 - 0.99 9.8 9.5 0.54 10.6 0.5 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HrpB7 PF09486.10 KLO09083.1 - 0.0039 17.6 17.6 0.0075 16.7 17.6 1.4 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) TolA_bind_tri PF16331.5 KLO09083.1 - 0.014 15.5 4.7 0.75 9.9 1.8 3.0 2 1 0 2 2 2 0 TolA binding protein trimerisation Spc7 PF08317.11 KLO09083.1 - 0.023 13.6 16.5 1.9 7.3 11.6 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein MMR_HSR1_C PF08438.10 KLO09083.1 - 0.035 14.7 1.7 0.059 13.9 0.8 1.9 2 0 0 2 2 1 0 GTPase of unknown function C-terminal CHDCT2 PF08074.11 KLO09083.1 - 0.08 13.1 5.9 0.047 13.9 3.5 1.8 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DUF1779 PF08680.10 KLO09083.1 - 0.12 12.6 4.8 0.21 11.8 4.8 1.3 1 0 0 1 1 1 0 TATA-box binding FUSC PF04632.12 KLO09083.1 - 0.17 10.4 12.3 0.25 9.9 12.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF5082 PF16888.5 KLO09083.1 - 0.21 11.9 9.6 0.59 10.4 3.3 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) DUF5403 PF17395.2 KLO09083.1 - 0.29 11.4 8.5 19 5.6 0.6 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5403) YabA PF06156.13 KLO09083.1 - 0.49 11.1 5.5 11 6.7 0.0 3.0 2 1 1 3 3 3 0 Initiation control protein YabA UPF0242 PF06785.11 KLO09083.1 - 0.67 10.0 10.4 5 7.2 8.7 2.3 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4239 PF14023.6 KLO09083.1 - 1.3 8.7 5.7 1.1 8.9 3.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Kre28 PF17097.5 KLO09083.1 - 1.5 7.7 13.4 4.6 6.1 13.4 2.1 1 1 0 1 1 1 0 Spindle pole body component DUF16 PF01519.16 KLO09083.1 - 1.8 9.1 10.1 0.8 10.2 3.3 2.7 2 1 0 3 3 3 0 Protein of unknown function DUF16 LUC7 PF03194.15 KLO09083.1 - 2.1 8.0 11.3 2 8.0 0.4 2.2 1 1 1 2 2 2 0 LUC7 N_terminus Atg14 PF10186.9 KLO09083.1 - 4.5 6.3 11.0 7.4 5.6 7.8 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 KLO09083.1 - 4.8 7.3 18.8 12 5.9 12.1 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ISG65-75 PF11727.8 KLO09083.1 - 7.1 5.8 11.8 1.4 8.1 5.2 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein TPR_MLP1_2 PF07926.12 KLO09084.1 - 0.00012 22.2 86.8 0.0047 17.0 18.3 6.3 2 1 4 6 6 6 3 TPR/MLP1/MLP2-like protein Leu_zip PF15294.6 KLO09084.1 - 0.0025 17.4 8.6 0.0025 17.4 8.6 5.7 2 1 4 6 6 6 3 Leucine zipper Filament PF00038.21 KLO09084.1 - 0.0025 17.5 43.5 0.0025 17.5 43.5 2.9 2 1 1 3 3 3 1 Intermediate filament protein IFT57 PF10498.9 KLO09084.1 - 0.0043 16.1 6.4 0.0043 16.1 6.4 4.5 2 1 1 4 4 4 1 Intra-flagellar transport protein 57 Forkhead PF00250.18 KLO09084.1 - 0.013 15.7 0.1 0.032 14.5 0.1 1.7 1 0 0 1 1 1 0 Forkhead domain ATG16 PF08614.11 KLO09084.1 - 0.016 15.5 14.7 0.016 15.5 14.7 6.2 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) T3SSipB PF16535.5 KLO09084.1 - 0.017 15.6 4.2 0.017 15.6 4.2 6.1 2 1 4 7 7 6 0 Type III cell invasion protein SipB Fez1 PF06818.15 KLO09084.1 - 0.086 13.3 70.5 0.11 13.0 17.9 5.6 2 1 3 5 5 5 0 Fez1 HAP1_N PF04849.13 KLO09084.1 - 0.21 10.8 67.1 0.013 14.8 11.5 4.4 2 1 2 4 4 4 0 HAP1 N-terminal conserved region PKcGMP_CC PF16808.5 KLO09084.1 - 0.23 11.3 0.1 0.23 11.3 0.1 7.6 8 0 0 8 8 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HMMR_N PF15905.5 KLO09084.1 - 0.28 10.6 74.7 0.11 11.9 22.3 4.1 2 1 3 5 5 5 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KLO09084.1 - 0.36 9.7 79.1 0.33 9.8 25.2 4.7 2 1 4 6 6 6 0 Spc7 kinetochore protein GAS PF13851.6 KLO09084.1 - 0.52 9.6 65.2 0.063 12.6 5.0 6.1 2 1 4 6 6 6 0 Growth-arrest specific micro-tubule binding MscS_porin PF12795.7 KLO09084.1 - 0.55 9.7 81.3 0.54 9.8 23.3 5.2 1 1 4 5 5 5 0 Mechanosensitive ion channel porin domain HOOK PF05622.12 KLO09084.1 - 0.69 8.0 71.2 0.025 12.7 9.1 3.5 2 1 2 4 4 4 0 HOOK protein FPP PF05911.11 KLO09084.1 - 0.78 7.8 66.1 0.42 8.7 26.7 3.6 2 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil EzrA PF06160.12 KLO09084.1 - 0.83 7.8 53.0 0.076 11.2 16.7 3.9 2 1 0 3 3 3 0 Septation ring formation regulator, EzrA APG6_N PF17675.1 KLO09084.1 - 1.4 9.4 75.2 1.4 9.5 9.4 5.0 2 1 1 3 3 2 0 Apg6 coiled-coil region Tektin PF03148.14 KLO09084.1 - 2.1 7.0 57.9 0.29 9.8 3.7 4.9 1 1 2 4 4 4 0 Tektin family BLOC1_2 PF10046.9 KLO09084.1 - 2.6 8.4 48.4 0.2 12.0 1.5 7.0 1 1 5 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 KLO09084.1 - 2.7 8.2 46.8 0.14 12.3 1.3 5.9 2 1 3 6 6 6 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.11 KLO09084.1 - 5.7 6.7 70.8 0.14 11.9 1.2 7.0 2 1 5 7 7 7 0 Phage minor structural protein GP20 LSM PF01423.22 KLO09085.1 - 9.6e-20 70.0 1.6 1.2e-19 69.7 1.6 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KLO09085.1 - 0.002 18.2 0.1 0.0026 17.9 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain BPL_C PF02237.17 KLO09085.1 - 0.032 14.1 1.1 0.037 13.9 0.2 1.5 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain Gemin7 PF11095.8 KLO09085.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) UNC-79 PF14776.6 KLO09086.1 - 0.14 10.8 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 CxC6 PF18721.1 KLO09087.1 - 0.081 13.2 5.3 0.88 9.9 0.2 3.2 3 0 0 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases GATA PF00320.27 KLO09087.1 - 0.37 10.4 3.2 7.3 6.3 0.1 2.6 2 0 0 2 2 2 0 GATA zinc finger CDC45 PF02724.14 KLO09087.1 - 1.2 7.4 6.6 7.8 4.6 0.1 2.2 2 0 0 2 2 2 0 CDC45-like protein ThiF PF00899.21 KLO09088.1 - 6.4e-30 104.3 0.0 7.9e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Fungal_trans PF04082.18 KLO09090.1 - 2.1e-19 69.6 0.0 3.5e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO09090.1 - 8.3e-07 29.0 10.0 1.5e-06 28.2 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1179 PF06678.11 KLO09090.1 - 0.48 10.4 1.9 7.5 6.6 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) zf_C2HC_14 PF18574.1 KLO09091.1 - 0.033 14.0 4.3 0.5 10.2 0.0 3.4 3 0 0 3 3 3 0 C2HC Zing finger domain PilW PF16074.5 KLO09091.1 - 0.12 12.4 0.7 3.5 7.7 0.6 2.4 2 0 0 2 2 2 0 Type IV Pilus-assembly protein W Thioredoxin_3 PF13192.6 KLO09091.1 - 0.19 11.8 0.1 4.1 7.5 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin domain PPR_2 PF13041.6 KLO09092.1 - 0.013 15.7 0.0 0.052 13.8 0.0 2.1 2 0 0 2 2 2 0 PPR repeat family zf-C2H2 PF00096.26 KLO09094.1 - 1.2e-09 38.1 9.7 5.7e-05 23.3 3.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO09094.1 - 1.6e-07 31.5 7.0 0.0014 19.3 2.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 KLO09094.1 - 9.2e-05 22.4 5.5 0.00086 19.3 1.8 2.4 1 1 1 2 2 2 1 BED zinc finger zf-H2C2_2 PF13465.6 KLO09094.1 - 0.0011 19.3 9.0 0.13 12.8 0.5 3.4 3 0 0 3 3 3 2 Zinc-finger double domain Elf1 PF05129.13 KLO09094.1 - 0.0075 16.3 0.1 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-C2HE PF16278.5 KLO09094.1 - 0.0078 16.6 3.1 0.88 10.1 0.1 2.6 3 0 0 3 3 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KLO09094.1 - 0.015 15.0 3.0 0.34 10.7 0.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 KLO09094.1 - 0.026 14.9 2.2 0.12 12.8 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KLO09094.1 - 0.045 14.1 4.0 0.31 11.4 0.4 2.7 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KLO09094.1 - 0.059 13.7 9.3 0.37 11.1 4.3 3.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding HNH_5 PF14279.6 KLO09094.1 - 0.061 13.2 2.1 4.4 7.2 0.1 2.5 2 0 0 2 2 2 0 HNH endonuclease zinc_ribbon_9 PF14369.6 KLO09094.1 - 0.28 11.5 2.9 0.82 10.0 0.8 2.3 2 0 0 2 2 2 0 zinc-ribbon zf-C2HC_2 PF13913.6 KLO09094.1 - 0.67 9.9 8.0 0.3 11.0 1.7 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KLO09094.1 - 0.68 10.3 9.5 0.71 10.2 0.6 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KLO09094.1 - 8.1 6.6 10.1 2.7 8.1 0.7 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Metallophos PF00149.28 KLO09096.1 - 7.9e-36 124.5 0.2 1e-35 124.1 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KLO09096.1 - 0.072 13.5 0.3 0.15 12.5 0.3 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KLO09096.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SET PF00856.28 KLO09098.1 - 6.2e-15 56.0 0.0 1.2e-14 55.1 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KLO09098.1 - 9.9e-13 48.9 0.0 2.8e-12 47.4 0.0 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding CENP-B_dimeris PF09026.10 KLO09098.1 - 0.48 10.8 10.6 1.1 9.7 10.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain F-box-like PF12937.7 KLO09099.1 - 5.3e-06 26.2 0.4 4.7e-05 23.2 0.2 2.6 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.7 KLO09100.1 - 6e-06 26.1 0.3 1.5e-05 24.8 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09100.1 - 0.0045 16.8 0.7 0.014 15.2 0.7 1.9 1 1 0 1 1 1 1 F-box domain CBFB_NFYA PF02045.15 KLO09101.1 - 4.9e-29 100.7 7.4 5.6e-29 100.5 7.4 1.0 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B peroxidase PF00141.23 KLO09102.1 - 5e-30 104.9 0.0 9e-30 104.1 0.0 1.4 1 1 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KLO09102.1 - 4e-26 90.8 2.8 5.6e-26 90.3 1.5 1.9 2 0 0 2 2 2 1 Fungal peroxidase extension region Rota_VP2 PF05087.12 KLO09103.1 - 0.0078 14.4 0.0 0.0087 14.3 0.0 1.0 1 0 0 1 1 1 1 Rotavirus VP2 protein Endonuclease_5 PF04493.14 KLO09103.1 - 0.057 13.1 0.0 0.064 12.9 0.0 1.0 1 0 0 1 1 1 0 Endonuclease V DltD PF04914.12 KLO09103.1 - 0.15 11.4 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 DltD protein SPC22 PF04573.12 KLO09104.1 - 2.3e-51 173.7 0.0 2.7e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Tweety PF04906.13 KLO09105.1 - 0.24 10.0 0.1 0.38 9.4 0.1 1.2 1 0 0 1 1 1 0 Tweety TFIIIC_sub6 PF10419.9 KLO09106.1 - 9.5e-13 47.8 0.0 1.1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain MFS_1 PF07690.16 KLO09107.1 - 5.3e-22 78.2 39.3 8.3e-22 77.6 39.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.22 KLO09108.1 - 5.8e-77 259.4 0.0 6.6e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO09109.1 - 3.6e-69 233.7 0.0 4.1e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CAP_GLY PF01302.25 KLO09110.1 - 3.4e-20 71.8 1.0 5.8e-20 71.1 1.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain HOOK PF05622.12 KLO09110.1 - 0.00062 18.1 19.4 0.00062 18.1 19.4 4.8 1 1 3 4 4 4 2 HOOK protein TMF_DNA_bd PF12329.8 KLO09110.1 - 0.0016 18.4 9.4 0.0016 18.4 9.4 10.0 7 3 2 9 9 9 3 TATA element modulatory factor 1 DNA binding GAS PF13851.6 KLO09110.1 - 0.0019 17.6 10.4 0.0019 17.6 10.4 6.3 2 2 2 6 6 6 2 Growth-arrest specific micro-tubule binding ThiS PF02597.20 KLO09110.1 - 0.01 16.4 0.1 0.44 11.2 0.1 3.9 1 0 0 1 1 1 0 ThiS family ATG16 PF08614.11 KLO09110.1 - 0.39 10.9 107.7 5.6 7.1 32.1 6.2 1 1 4 6 6 6 0 Autophagy protein 16 (ATG16) CLIP1_ZNF PF16641.5 KLO09110.1 - 0.74 9.8 12.4 0.088 12.7 2.5 2.4 2 0 0 2 2 2 0 CLIP1 zinc knuckle DUF4407 PF14362.6 KLO09110.1 - 7.6 5.8 77.4 1 8.7 16.9 4.9 1 1 4 5 5 5 0 Domain of unknown function (DUF4407) ERG4_ERG24 PF01222.17 KLO09111.1 - 1.7e-140 468.6 7.2 1.9e-140 468.5 7.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KLO09111.1 - 2.9e-07 30.2 0.1 6.6e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KLO09111.1 - 0.00075 19.9 0.4 0.0075 16.6 0.0 2.7 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KLO09111.1 - 0.014 15.8 0.0 0.059 13.8 0.0 2.1 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF5539 PF17693.1 KLO09113.1 - 7.8 6.1 13.3 9.5 5.8 13.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5539) TPR_2 PF07719.17 KLO09114.1 - 1.3e-31 106.1 16.2 0.00024 21.0 0.1 13.3 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_1 PF00515.28 KLO09114.1 - 1.2e-30 104.0 16.6 0.00014 21.5 0.0 12.1 14 0 0 14 14 14 8 Tetratricopeptide repeat TPR_8 PF13181.6 KLO09114.1 - 1.8e-24 83.9 11.6 0.0024 18.0 0.1 12.4 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.6 KLO09114.1 - 3.7e-24 85.0 29.9 1.2e-06 28.9 0.8 10.7 9 2 1 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 KLO09114.1 - 9.1e-19 66.6 25.3 0.00097 19.8 0.3 12.5 9 3 4 13 13 12 4 Tetratricopeptide repeat TPR_12 PF13424.6 KLO09114.1 - 1.1e-16 60.8 19.7 0.00014 22.0 0.6 9.8 7 3 5 12 12 12 6 Tetratricopeptide repeat TPR_17 PF13431.6 KLO09114.1 - 1.3e-14 53.4 11.6 4.7 7.8 0.1 12.3 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_16 PF13432.6 KLO09114.1 - 1.3e-14 54.5 35.6 0.00087 19.9 0.1 12.0 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_6 PF13174.6 KLO09114.1 - 9.1e-14 51.1 20.7 7e-06 26.3 0.1 10.9 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_7 PF13176.6 KLO09114.1 - 3.1e-11 42.5 12.4 0.026 14.5 0.0 8.9 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 KLO09114.1 - 8.5e-10 38.2 8.2 0.9 9.3 0.0 8.5 7 2 2 9 9 9 4 TPR repeat ANAPC3 PF12895.7 KLO09114.1 - 0.00016 21.9 8.9 7.9 6.8 0.0 6.7 7 0 0 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KLO09114.1 - 0.00029 20.6 25.1 0.23 11.4 0.2 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat ChAPs PF09295.10 KLO09114.1 - 0.008 15.2 0.1 0.45 9.5 0.0 2.7 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 KLO09114.1 - 0.32 11.8 8.3 4.2 8.3 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Hydrophobin PF01185.18 KLO09115.1 - 3.4e-25 88.5 10.5 4.7e-25 88.0 10.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF1427 PF07235.11 KLO09115.1 - 0.053 13.5 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) LysM PF01476.20 KLO09116.1 - 8e-05 22.6 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 LysM domain CLASP_N PF12348.8 KLO09117.1 - 6.5e-25 88.0 0.1 7.7e-25 87.8 0.1 1.0 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 KLO09117.1 - 0.71 10.3 3.2 26 5.4 0.1 3.9 4 1 0 4 4 4 0 HEAT repeat LRR_4 PF12799.7 KLO09118.1 - 0.077 13.5 0.3 59 4.3 0.1 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 KLO09119.1 - 8.2e-62 208.9 0.0 9.6e-62 208.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO09119.1 - 1.5e-44 152.3 0.0 1.8e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO09119.1 - 1.5e-07 30.6 0.2 4.8e-07 28.9 0.0 1.8 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 KLO09119.1 - 0.0016 17.8 0.1 0.0032 16.8 0.1 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO09119.1 - 0.0069 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO09119.1 - 0.017 15.0 0.0 7.2 6.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KLO09119.1 - 0.021 13.8 1.8 0.087 11.8 0.1 2.4 3 0 0 3 3 3 0 Haspin like kinase domain RIO1 PF01163.22 KLO09119.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KLO09119.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APS_kinase PF01583.20 KLO09120.1 - 1.4e-70 236.3 0.0 1.6e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KLO09120.1 - 0.00011 22.4 0.0 0.00025 21.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KLO09120.1 - 0.00049 20.7 0.0 0.00084 19.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KLO09120.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.10 KLO09120.1 - 0.02 14.3 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 G-alpha PF00503.20 KLO09120.1 - 0.062 12.5 0.1 0.11 11.6 0.0 1.4 2 0 0 2 2 2 0 G-protein alpha subunit CPT PF07931.12 KLO09120.1 - 0.11 12.3 0.0 0.71 9.7 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 KLO09120.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin CybS PF05328.12 KLO09121.1 - 4.2e-41 139.7 0.0 5.2e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Hemerythrin PF01814.23 KLO09122.1 - 2.6e-14 54.0 0.6 3.8e-14 53.4 0.6 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HAD_2 PF13419.6 KLO09123.1 - 1.6e-06 28.3 0.0 3.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO09123.1 - 0.00016 21.7 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.8 KLO09123.1 - 0.036 13.5 0.2 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) NIF PF03031.18 KLO09123.1 - 0.049 13.4 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase HAD_2 PF13419.6 KLO09124.1 - 1.2e-05 25.4 0.0 2.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO09124.1 - 0.002 18.2 0.0 0.0061 16.6 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like GST_N_3 PF13417.6 KLO09127.1 - 3.9e-10 40.0 0.0 9.2e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO09127.1 - 2.7e-09 37.1 0.0 5.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KLO09127.1 - 3.6e-09 36.8 0.0 4.9e-08 33.2 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO09127.1 - 9.9e-07 29.0 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KLO09127.1 - 2e-06 27.9 0.0 3.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KLO09127.1 - 2.4e-06 27.5 0.1 4e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KLO09127.1 - 0.054 13.3 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 KLO09128.1 - 3.1e-07 30.2 0.3 2.1e-06 27.5 0.0 2.7 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO09129.1 - 1.8e-06 27.7 2.0 1.2e-05 25.1 0.1 2.9 3 0 0 3 3 3 1 F-box-like DUF3517 PF12030.8 KLO09129.1 - 0.054 12.4 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) F-box-like_2 PF13013.6 KLO09129.1 - 0.067 13.2 0.3 0.16 12.0 0.1 1.7 2 0 0 2 2 2 0 F-box-like domain F-box-like PF12937.7 KLO09130.1 - 9.6e-08 31.8 1.7 2.1e-07 30.7 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO09130.1 - 0.0041 17.0 0.0 0.025 14.5 0.0 2.4 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO09131.1 - 1e-07 31.8 6.6 2.3e-07 30.6 0.8 3.0 3 0 0 3 3 3 1 F-box-like DUF3517 PF12030.8 KLO09131.1 - 0.0027 16.7 0.1 0.0044 16.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) Cytokin_check_N PF10407.9 KLO09131.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus Ferrochelatase PF00762.19 KLO09133.1 - 1.4e-101 339.7 0.0 1.6e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase DUF389 PF04087.14 KLO09134.1 - 0.0026 17.8 2.5 0.0048 17.0 2.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF389) DDE_Tnp_4 PF13359.6 KLO09136.1 - 5.8e-24 84.6 0.0 9.7e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KLO09136.1 - 0.00063 19.5 0.0 0.0024 17.6 0.0 1.8 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 KLO09137.1 - 0.091 13.1 0.5 0.091 13.1 0.5 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain hNIFK_binding PF12196.8 KLO09137.1 - 0.46 10.0 3.5 1.6 8.3 3.5 1.9 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK DUF2408 PF10303.9 KLO09137.1 - 2.9 8.4 8.7 7.4 7.2 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) UTP25 PF06862.12 KLO09138.1 - 0.15 10.8 0.3 13 4.4 0.1 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Vac14_Fig4_bd PF11916.8 KLO09138.1 - 0.15 11.7 2.1 0.33 10.6 0.2 2.2 2 0 0 2 2 2 0 Vacuolar protein 14 C-terminal Fig4p binding TMEM43 PF07787.12 KLO09138.1 - 2 7.8 7.8 1.9 7.8 0.8 2.4 2 0 0 2 2 2 0 Transmembrane protein 43 F-box-like PF12937.7 KLO09141.1 - 8.1e-09 35.2 0.0 4.7e-08 32.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like Con-6 PF10346.9 KLO09142.1 - 1.9e-09 37.4 0.9 4.1e-09 36.3 0.1 1.9 2 0 0 2 2 2 1 Conidiation protein 6 HWE_HK PF07536.14 KLO09142.1 - 0.092 13.5 2.0 0.29 11.9 0.7 2.0 2 0 0 2 2 2 0 HWE histidine kinase zf-CCCH_6 PF18585.1 KLO09142.1 - 0.11 12.4 0.2 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 GMC_oxred_N PF00732.19 KLO09144.1 - 2.1e-63 214.4 0.0 2.8e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO09144.1 - 2e-33 115.9 0.0 4e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KLO09144.1 - 8.9e-05 21.8 0.1 0.00019 20.8 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KLO09144.1 - 0.00011 21.4 0.0 0.00023 20.4 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KLO09144.1 - 0.00013 22.1 0.1 0.00044 20.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO09144.1 - 0.00026 20.7 1.6 0.00028 20.6 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO09144.1 - 0.0012 18.1 0.9 0.0026 16.9 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO09144.1 - 0.0014 18.0 0.2 0.0041 16.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KLO09144.1 - 0.006 16.8 0.1 0.098 12.9 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_3 PF13738.6 KLO09144.1 - 0.03 13.6 0.2 0.24 10.6 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO09144.1 - 0.043 12.5 0.4 0.15 10.7 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 KLO09144.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ADH_N PF08240.12 KLO09145.1 - 5.5e-26 90.6 0.1 8.9e-26 89.9 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO09145.1 - 3.5e-08 33.5 0.0 1.3e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO09145.1 - 0.011 16.8 0.0 0.047 14.7 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_9 PF13454.6 KLO09145.1 - 0.091 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding NADH_4Fe-4S PF10589.9 KLO09145.1 - 0.35 11.0 2.3 0.8 9.8 2.3 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DctP PF03480.13 KLO09146.1 - 0.27 10.5 3.6 0.54 9.5 3.6 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 ARGLU PF15346.6 KLO09146.1 - 0.49 10.3 28.7 0.053 13.4 24.2 1.7 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Fe-ADH PF00465.19 KLO09147.1 - 3.5e-68 230.1 0.0 4.4e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KLO09147.1 - 7.9e-15 55.2 0.0 1.5e-14 54.3 0.0 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase PFK PF00365.20 KLO09147.1 - 0.057 12.7 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphofructokinase FUSC_2 PF13515.6 KLO09148.1 - 2.8e-21 75.9 7.1 2.8e-21 75.9 7.1 2.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 KLO09148.1 - 1.6e-13 50.2 18.7 9.7e-13 47.5 3.4 3.4 2 1 0 3 3 3 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 KLO09148.1 - 1.5e-09 38.0 1.3 1.4e-08 34.9 0.4 2.3 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 KLO09148.1 - 1e-07 31.2 10.4 6e-07 28.7 7.5 2.5 2 0 0 2 2 2 1 Aluminium activated malate transporter ArAE_1 PF06081.11 KLO09148.1 - 0.0013 18.9 3.3 0.0013 18.9 3.3 3.1 3 2 1 4 4 4 1 Aromatic acid exporter family member 1 DUF3584 PF12128.8 KLO09148.1 - 0.19 9.2 1.9 0.31 8.5 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HSP70 PF00012.20 KLO09149.1 - 0.00032 19.0 0.0 0.00053 18.3 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein Abhydrolase_3 PF07859.13 KLO09150.1 - 2.4e-26 92.9 0.0 4.9e-26 91.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO09150.1 - 1.5e-12 47.1 0.0 5.1e-11 42.1 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase ATG16 PF08614.11 KLO09151.1 - 0.083 13.1 1.7 0.12 12.6 1.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_18 PF13238.6 KLO09152.1 - 3.1e-06 27.8 0.6 7.5e-05 23.3 0.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KLO09152.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KLO09152.1 - 0.058 13.8 0.3 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KLO09152.1 - 0.074 12.8 0.1 0.31 10.7 0.1 2.1 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KLO09152.1 - 0.093 12.9 0.2 0.71 10.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KLO09152.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 KLO09152.1 - 0.17 10.9 0.1 0.26 10.3 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein dNK PF01712.19 KLO09152.1 - 0.19 11.6 0.6 1.6 8.6 0.6 2.3 1 1 0 1 1 1 0 Deoxynucleoside kinase Peptidase_M28 PF04389.17 KLO09153.1 - 1.1e-33 116.6 0.0 1.7e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KLO09153.1 - 0.00077 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KLO09153.1 - 0.019 14.0 0.0 0.048 12.7 0.0 1.5 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase ThrE PF06738.12 KLO09153.1 - 0.054 12.9 7.1 0.081 12.3 1.1 2.7 3 0 0 3 3 3 0 Putative threonine/serine exporter Peptidase_M28 PF04389.17 KLO09154.1 - 5.8e-31 107.7 0.0 9.9e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KLO09154.1 - 0.049 13.3 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Cellulose_synt PF03552.14 KLO09154.1 - 0.18 10.3 0.2 0.34 9.3 0.2 1.4 1 0 0 1 1 1 0 Cellulose synthase ThrE PF06738.12 KLO09154.1 - 0.63 9.4 3.9 1.3 8.3 0.2 2.8 3 0 0 3 3 3 0 Putative threonine/serine exporter BTB PF00651.31 KLO09155.1 - 3.4e-05 24.0 0.0 6.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SapB_1 PF05184.15 KLO09155.1 - 0.1 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 1 BTB PF00651.31 KLO09156.1 - 0.00018 21.7 0.1 0.00052 20.2 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain TSLP PF15216.6 KLO09156.1 - 0.054 13.8 1.8 0.13 12.6 1.8 1.6 1 0 0 1 1 1 0 Thymic stromal lymphopoietin Pmp3 PF01679.17 KLO09161.1 - 1.6e-11 44.2 3.8 1.6e-11 44.2 3.8 1.6 2 0 0 2 2 2 1 Proteolipid membrane potential modulator Ribosomal_L14 PF00238.19 KLO09165.1 - 2e-31 108.6 0.0 2.5e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e zf-MYND PF01753.18 KLO09168.1 - 9.7e-11 41.6 11.2 3e-10 40.0 11.2 1.9 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO09168.1 - 9.1 6.5 12.8 2.9 8.1 8.3 2.5 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO09171.1 - 9e-10 38.5 10.4 9e-10 38.5 10.4 1.6 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KLO09171.1 - 0.37 11.1 7.2 0.86 10.0 7.2 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-RING_2 PF13639.6 KLO09171.1 - 0.64 10.4 7.5 1.1 9.6 7.5 1.4 1 0 0 1 1 1 0 Ring finger domain HET PF06985.11 KLO09173.1 - 9.3e-05 22.8 0.0 0.072 13.4 0.0 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Nup88 PF10168.9 KLO09174.1 - 0.0058 14.5 0.0 0.0081 14.0 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore component zf-MYND PF01753.18 KLO09175.1 - 9.8e-08 32.0 13.8 9.8e-08 32.0 13.8 1.7 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KLO09175.1 - 0.3 11.4 9.9 0.88 9.9 9.9 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KLO09176.1 - 0.022 14.8 2.5 0.022 14.8 2.5 2.3 2 0 0 2 2 2 0 MYND finger HSBP1 PF06825.12 KLO09180.1 - 7.7e-15 54.5 6.6 1.1e-14 54.0 6.6 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 PMC2NT PF08066.12 KLO09180.1 - 0.055 14.1 2.1 0.12 13.1 0.4 2.0 1 1 1 2 2 2 0 PMC2NT (NUC016) domain NPV_P10 PF05531.12 KLO09180.1 - 0.055 13.9 0.4 0.081 13.4 0.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein BORCS6 PF10157.9 KLO09180.1 - 0.076 13.2 2.1 0.11 12.8 2.1 1.2 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Baculo_PEP_C PF04513.12 KLO09180.1 - 0.089 12.8 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 KLO09180.1 - 0.31 11.4 1.6 0.73 10.3 0.2 2.1 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Terpene_synth_C PF03936.16 KLO09181.1 - 5e-06 26.0 0.0 0.00018 21.0 0.0 2.3 2 1 0 2 2 2 2 Terpene synthase family, metal binding domain MCM6_C PF18263.1 KLO09181.1 - 0.034 14.4 0.0 0.079 13.2 0.0 1.7 1 1 0 1 1 1 0 MCM6 C-terminal winged-helix domain Acyltransf_C PF16076.5 KLO09182.1 - 0.054 13.6 0.6 0.78 9.9 0.1 2.4 2 0 0 2 2 2 0 Acyltransferase C-terminus MFS_1 PF07690.16 KLO09183.1 - 1.1e-48 165.9 42.9 2.2e-47 161.7 44.4 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO09183.1 - 1.5e-14 53.7 12.3 1.5e-14 53.7 12.3 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KLO09183.1 - 6.6e-13 48.0 13.4 1e-12 47.3 13.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Shisa PF13908.6 KLO09184.1 - 0.075 13.3 4.0 0.33 11.2 0.0 2.6 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 KLO09184.1 - 0.18 12.1 0.3 46 4.4 0.0 2.8 2 1 0 3 3 3 0 Orf78 (ac78) MIP PF00230.20 KLO09185.1 - 7.7e-52 176.3 10.3 9.8e-52 175.9 10.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein Topoisom_I_N PF02919.15 KLO09186.1 - 0.0083 15.7 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Multi_Drug_Res PF00893.19 KLO09186.1 - 5.1 7.8 7.1 11 6.8 0.3 2.4 2 0 0 2 2 2 0 Small Multidrug Resistance protein DUF2721 PF11026.8 KLO09186.1 - 6.2 6.7 9.4 1.3 8.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) TrkH PF02386.16 KLO09187.1 - 7.7e-109 364.4 8.6 1.2e-108 363.7 2.7 2.2 2 0 0 2 2 2 2 Cation transport protein Oxysterol_BP PF01237.18 KLO09188.1 - 3.9e-45 154.3 3.1 9.3e-26 90.5 2.3 3.2 2 1 0 2 2 2 2 Oxysterol-binding protein Trp_oprn_chp PF09534.10 KLO09189.1 - 0.027 14.3 0.7 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4690 PF15756.5 KLO09189.1 - 3.9 8.1 7.4 0.67 10.6 1.6 2.6 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF2145 PF09916.9 KLO09192.1 - 0.07 12.8 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) PEPcase PF00311.17 KLO09197.1 - 0.14 10.2 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase CBFD_NFYB_HMF PF00808.23 KLO09204.1 - 5.6e-27 93.8 0.4 8.7e-27 93.2 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KLO09204.1 - 0.00041 20.7 0.0 0.00064 20.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KLO09204.1 - 0.0051 16.8 0.0 0.0086 16.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KLO09204.1 - 0.026 14.7 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold preSET_CXC PF18264.1 KLO09205.1 - 2.9e-07 30.8 17.4 2.9e-07 30.8 17.4 5.2 4 1 1 5 5 5 2 CXC domain SET PF00856.28 KLO09205.1 - 9e-06 26.2 0.3 9e-06 26.2 0.3 2.3 2 1 0 2 2 2 1 SET domain UDG PF03167.19 KLO09206.1 - 3.6e-17 62.8 0.0 4.8e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sec63 PF02889.16 KLO09207.1 - 2.4e-161 534.9 0.0 1.1e-87 293.5 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KLO09207.1 - 7.1e-46 156.2 0.2 8.4e-26 90.8 0.1 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KLO09207.1 - 2e-33 114.9 0.0 5.6e-33 113.4 0.0 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KLO09207.1 - 1.8e-25 89.9 0.0 6.5e-17 62.1 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KLO09207.1 - 1.7e-13 50.9 0.1 6.1e-08 33.0 0.0 3.6 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KLO09207.1 - 3.3e-06 27.4 0.0 0.038 14.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KLO09207.1 - 0.00065 20.1 1.1 1.3 9.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain PhoH PF02562.16 KLO09207.1 - 0.00075 19.0 0.0 0.067 12.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 KLO09207.1 - 0.52 10.1 2.7 33 4.1 0.0 3.8 3 1 1 4 4 4 0 AAA domain Fungal_trans PF04082.18 KLO09208.1 - 3.6e-06 26.2 0.8 5.7e-06 25.6 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain YvrJ PF12841.7 KLO09208.1 - 0.35 10.4 1.3 5.8 6.5 0.5 2.3 2 0 0 2 2 2 0 YvrJ protein family WD40 PF00400.32 KLO09209.1 - 1.9e-07 31.6 10.9 0.13 13.2 0.0 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat SRA1 PF07304.11 KLO09209.1 - 0.0067 16.2 1.6 0.0067 16.2 1.6 2.9 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) ATP_bind_1 PF03029.17 KLO09210.1 - 1.1e-74 251.3 0.0 1.4e-74 251.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CPSF_A PF03178.15 KLO09211.1 - 1.3e-79 267.8 0.0 1.5e-78 264.4 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region NTP_transf_5 PF14907.6 KLO09212.1 - 0.0024 17.6 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase DEAD PF00270.29 KLO09213.1 - 5.9e-16 58.7 0.0 1.2e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO09213.1 - 1.4e-15 57.6 0.0 1.3e-12 48.0 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KLO09213.1 - 6.7e-10 39.6 0.3 1.9e-09 38.1 0.3 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KLO09213.1 - 5.2e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF5082 PF16888.5 KLO09213.1 - 0.0083 16.4 0.9 0.018 15.3 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) DUF615 PF04751.14 KLO09213.1 - 0.0097 15.9 1.6 0.022 14.8 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF615) APG6_N PF17675.1 KLO09213.1 - 0.014 16.0 1.5 0.014 16.0 1.5 2.1 2 0 0 2 2 1 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KLO09213.1 - 0.019 15.2 0.9 0.019 15.2 0.9 2.0 2 0 0 2 2 1 0 TATA element modulatory factor 1 TATA binding AAA_22 PF13401.6 KLO09213.1 - 0.067 13.5 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Osmo_CC PF08946.10 KLO09213.1 - 0.27 11.5 3.7 0.25 11.6 0.5 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil GAPT PF11770.8 KLO09213.1 - 0.47 10.3 2.7 0.98 9.3 2.7 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) ZapB PF06005.12 KLO09213.1 - 0.49 10.9 2.9 1.5 9.4 2.9 1.8 1 0 0 1 1 1 0 Cell division protein ZapB SAGA-Tad1 PF12767.7 KLO09213.1 - 7.1 6.3 6.7 9.4 5.9 1.6 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3176 PF11374.8 KLO09214.1 - 0.57 10.4 5.0 0.077 13.2 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) DUF202 PF02656.15 KLO09216.1 - 0.01 16.3 3.8 0.033 14.6 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Pullulanase_N2 PF17967.1 KLO09217.1 - 0.19 12.6 0.0 0.3 12.0 0.0 1.3 1 0 0 1 1 1 0 Pullulanase N2 domain RAD51_interact PF15696.5 KLO09220.1 - 0.049 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 RAD51 interacting motif Abhydrolase_3 PF07859.13 KLO09222.1 - 3.5e-29 102.2 0.0 4.9e-22 78.8 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO09222.1 - 0.00091 18.2 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2034 PF10356.9 KLO09223.1 - 1.9e-24 86.1 0.0 5e-12 45.6 0.0 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KLO09223.1 - 2.2e-06 27.7 0.0 1.7e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Restriction endonuclease Trm112p PF03966.16 KLO09224.1 - 8.5e-21 74.3 0.1 1.1e-20 74.0 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein zf-UDP PF14569.6 KLO09224.1 - 0.018 15.2 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 KLO09224.1 - 0.041 13.7 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_4 PF13717.6 KLO09224.1 - 0.055 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KLO09224.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF334 PF03904.13 KLO09224.1 - 0.15 11.5 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) zf-C2H2_4 PF13894.6 KLO09225.1 - 0.17 12.8 8.2 1.6 9.8 0.4 3.5 2 1 1 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.7 KLO09225.1 - 5.4 7.1 6.7 0.73 9.9 0.9 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Mt_ATP-synt_B PF05405.14 KLO09226.1 - 0.13 11.9 1.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Plavaka PF18759.1 KLO09228.1 - 1.6e-112 375.9 0.1 2.2e-112 375.5 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_12 PF18658.1 KLO09230.1 - 0.0065 16.0 0.1 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KLO09230.1 - 0.0082 16.5 2.8 0.021 15.2 2.8 1.7 1 0 0 1 1 1 1 Zinc-finger double domain CW_binding_1 PF01473.20 KLO09230.1 - 0.27 11.6 2.0 0.57 10.6 2.0 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat zf-C2H2_4 PF13894.6 KLO09230.1 - 2.4 9.2 12.3 5.1 8.2 3.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO09232.1 - 1.2e-11 44.4 9.4 0.00047 20.5 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO09232.1 - 1.8e-06 28.3 9.9 0.035 14.9 0.3 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KLO09232.1 - 1.8e-05 24.9 7.9 7.6e-05 23.0 0.1 4.1 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KLO09232.1 - 7.7e-05 22.6 5.2 0.036 14.1 0.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger DGF-1_C PF11040.8 KLO09232.1 - 0.36 10.9 2.6 0.44 10.6 0.8 2.2 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus zf-C2H2_aberr PF17017.5 KLO09232.1 - 0.66 10.1 3.0 8.9 6.4 0.0 2.9 1 1 2 3 3 3 0 Aberrant zinc-finger Pam16 PF03656.13 KLO09234.1 - 0.0011 19.0 0.0 0.0011 18.9 0.0 1.0 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 KLO09234.1 - 0.0017 18.4 0.0 0.0027 17.8 0.0 1.3 1 1 0 1 1 1 1 DnaJ domain Osmo_CC PF08946.10 KLO09234.1 - 0.57 10.5 3.7 12 6.3 0.1 2.8 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Carn_acyltransf PF00755.20 KLO09235.1 - 1.5e-162 542.3 0.0 1.7e-162 542.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3421 PF11901.8 KLO09236.1 - 1.3e-23 83.2 0.1 3.6e-23 81.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3421) ABA_WDS PF02496.16 KLO09236.1 - 0.012 16.1 0.4 0.03 14.8 0.4 1.7 1 0 0 1 1 1 0 ABA/WDS induced protein NCE101 PF11654.8 KLO09236.1 - 0.41 10.4 1.1 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Non-classical export protein 1 TPR_1 PF00515.28 KLO09238.1 - 6.2e-18 63.8 4.3 0.00016 21.3 0.5 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KLO09238.1 - 2.9e-13 48.8 9.9 0.015 15.4 0.0 5.6 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KLO09238.1 - 8.7e-13 47.4 2.6 0.0099 16.0 0.2 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KLO09238.1 - 1.4e-11 44.2 8.2 0.046 14.5 0.2 5.6 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.6 KLO09238.1 - 7.2e-11 42.4 7.3 0.00068 20.1 0.1 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KLO09238.1 - 1.5e-10 40.6 4.0 0.0012 18.4 0.6 4.6 3 1 1 4 4 4 3 TPR repeat TPR_17 PF13431.6 KLO09238.1 - 3.1e-10 39.7 5.8 0.45 11.0 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KLO09238.1 - 1.9e-08 34.8 9.1 5.3e-05 23.8 0.4 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KLO09238.1 - 2.9e-08 33.9 4.5 0.0049 17.1 1.8 3.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KLO09238.1 - 3.3e-06 27.2 5.2 0.0036 17.4 0.3 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.6 KLO09238.1 - 0.0001 22.5 5.1 2.5 8.5 0.1 5.0 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KLO09238.1 - 0.00017 20.9 2.8 0.0043 16.3 0.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KLO09238.1 - 0.00036 20.4 2.8 17 5.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO09238.1 - 0.0059 16.8 1.7 0.056 13.7 0.5 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KLO09238.1 - 4.8 7.2 10.3 3.3 7.7 1.9 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC_CDC26 PF10471.9 KLO09239.1 - 1.6e-06 28.8 7.2 2.2e-06 28.4 7.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 PRA1 PF03208.19 KLO09240.1 - 9.6e-36 122.5 0.2 1.1e-35 122.4 0.2 1.0 1 0 0 1 1 1 1 PRA1 family protein FA_desaturase PF00487.24 KLO09240.1 - 0.043 13.7 1.9 0.057 13.2 1.9 1.1 1 0 0 1 1 1 0 Fatty acid desaturase MPS-4 PF17523.2 KLO09240.1 - 0.093 12.9 0.9 0.17 12.0 0.5 1.6 1 1 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 PAS PF00989.25 KLO09241.1 - 0.00012 22.0 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 KLO09241.1 - 0.00026 21.0 11.4 0.00055 20.0 11.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrmC_N PF17827.1 KLO09242.1 - 1.1e-05 26.0 1.7 1.5e-05 25.5 0.1 2.2 3 1 0 3 3 1 1 PrmC N-terminal domain MTS PF05175.14 KLO09242.1 - 1.4e-05 24.7 0.4 0.00071 19.2 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KLO09242.1 - 5.3e-05 23.1 0.0 0.00019 21.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO09242.1 - 9e-05 23.1 0.0 0.00034 21.2 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain AviRa PF11599.8 KLO09242.1 - 0.003 17.0 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 RRNA methyltransferase AviRa PrmA PF06325.13 KLO09242.1 - 0.0056 16.1 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KLO09242.1 - 0.0056 16.5 0.0 0.031 14.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO09242.1 - 0.029 15.0 0.2 0.095 13.4 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 KLO09242.1 - 0.032 13.6 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 KLO09242.1 - 0.12 12.1 0.9 4.3 7.0 0.9 2.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 KLO09242.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Tfb4 PF03850.14 KLO09243.1 - 2.9e-75 253.3 0.0 3.8e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-TRAF PF02176.18 KLO09244.1 - 1.8e-10 41.3 36.3 1.7e-06 28.6 3.2 4.5 1 1 3 4 4 4 2 TRAF-type zinc finger U-box PF04564.15 KLO09244.1 - 6.6e-06 26.2 0.1 8.3e-05 22.7 0.0 2.6 1 1 1 2 2 2 1 U-box domain zf-C3HC4_2 PF13923.6 KLO09244.1 - 6.9e-06 25.8 17.1 6.9e-06 25.8 17.1 4.1 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO09244.1 - 9.4e-05 22.7 17.3 9.4e-05 22.7 17.3 4.0 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 KLO09244.1 - 0.00028 20.7 18.1 0.00028 20.7 18.1 4.2 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 KLO09244.1 - 0.00028 21.3 4.7 0.00028 21.3 4.7 4.2 1 1 3 4 4 3 2 TRAF-like zinc-finger zf-Nse PF11789.8 KLO09244.1 - 0.00031 20.5 9.5 0.00031 20.5 9.5 3.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit LRS4 PF10422.9 KLO09244.1 - 0.0004 20.0 0.2 0.0046 16.6 0.1 2.2 2 0 0 2 2 2 1 Monopolin complex subunit LRS4 zf-RING_6 PF14835.6 KLO09244.1 - 0.00058 19.7 6.1 0.0019 18.0 6.1 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KLO09244.1 - 0.00084 19.2 16.4 0.00084 19.2 16.4 3.8 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KLO09244.1 - 0.00096 19.0 14.6 0.00096 19.0 14.6 4.1 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO09244.1 - 0.0011 18.9 19.1 0.0011 18.9 19.1 3.2 3 1 0 3 3 2 1 RING-type zinc-finger CCDC144C PF14915.6 KLO09244.1 - 0.0036 16.5 0.4 0.0088 15.2 0.4 1.5 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region zf-ACC PF17848.1 KLO09244.1 - 0.014 15.4 11.0 3.7 7.7 0.4 4.4 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zf-rbx1 PF12678.7 KLO09244.1 - 0.017 15.4 12.8 0.017 15.4 12.8 3.8 3 1 0 3 3 3 0 RING-H2 zinc finger domain Sina PF03145.16 KLO09244.1 - 0.023 14.6 19.2 0.073 13.0 1.3 3.3 1 1 2 3 3 3 0 Seven in absentia protein family Uso1_p115_C PF04871.13 KLO09244.1 - 0.12 12.8 1.2 3.1 8.2 1.3 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 KLO09244.1 - 0.12 11.7 0.5 0.6 9.4 0.2 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sas6_CC PF18594.1 KLO09244.1 - 0.54 10.1 4.9 0.31 10.8 0.5 2.4 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain TSC22 PF01166.18 KLO09244.1 - 0.67 10.3 2.6 36 4.8 0.2 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KLO09244.1 - 3.7 7.7 9.6 19 5.4 0.0 3.1 3 0 0 3 3 3 0 bZIP transcription factor Methyltransf_23 PF13489.6 KLO09245.1 - 1.5e-18 67.2 0.0 2.3e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO09245.1 - 2.1e-13 50.3 0.0 2.5e-12 46.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO09245.1 - 9.9e-13 48.6 0.0 2.7e-12 47.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO09245.1 - 5.9e-12 46.1 0.0 1.2e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO09245.1 - 7.3e-10 39.5 0.0 2.2e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KLO09245.1 - 3.3e-06 26.7 0.0 6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.15 KLO09245.1 - 0.00092 18.6 0.0 0.0025 17.2 0.0 1.6 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G PrmA PF06325.13 KLO09245.1 - 0.0034 16.8 0.0 0.0066 15.9 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KLO09245.1 - 0.0047 16.3 0.0 0.042 13.2 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KLO09245.1 - 0.0098 15.5 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KLO09245.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_15 PF09445.10 KLO09245.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF938 PF06080.12 KLO09245.1 - 0.022 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 KLO09245.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Homeodomain PF00046.29 KLO09247.1 - 1.1e-14 54.1 0.9 1.7e-14 53.4 0.9 1.3 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 KLO09248.1 - 2.9e-44 151.4 0.0 3.9e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO09248.1 - 4.3e-28 98.3 0.0 6.4e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KLO09248.1 - 0.0005 19.5 0.0 0.00079 18.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPP1 PF10341.9 KLO09249.1 - 2.7e-07 30.5 0.0 8.9e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Ribosomal_S7 PF00177.21 KLO09251.1 - 1.7e-26 92.6 0.1 3.2e-26 91.8 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e MCD PF05292.11 KLO09251.1 - 0.07 12.7 0.2 0.1 12.2 0.2 1.2 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain GPI-anchored PF10342.9 KLO09252.1 - 1.9e-06 28.5 0.2 3.4e-06 27.7 0.2 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TMEM37 PF15108.6 KLO09253.1 - 0.011 15.6 0.4 0.011 15.6 0.4 2.4 2 1 1 3 3 3 0 Voltage-dependent calcium channel gamma-like subunit protein family F-box-like PF12937.7 KLO09254.1 - 4.4e-06 26.5 0.5 9.5e-06 25.4 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09254.1 - 0.084 12.8 0.6 0.37 10.7 0.5 2.1 2 0 0 2 2 2 0 F-box domain DUF3872 PF12988.7 KLO09256.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) Phage_holin_4_1 PF05105.12 KLO09257.1 - 0.0042 17.2 0.2 0.0059 16.7 0.2 1.2 1 0 0 1 1 1 1 Bacteriophage holin family Fip1 PF05182.13 KLO09259.1 - 2.4e-20 71.8 1.2 3.8e-20 71.1 1.2 1.3 1 0 0 1 1 1 1 Fip1 motif VIT PF08487.10 KLO09260.1 - 3.6e-31 107.6 0.1 6.9e-31 106.8 0.1 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KLO09260.1 - 1.6e-24 86.6 0.0 3.3e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KLO09260.1 - 2.1e-14 54.1 0.0 4.4e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KLO09260.1 - 1.3e-11 45.1 0.0 4.7e-11 43.3 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KLO09260.1 - 8.1e-07 28.7 0.1 1.4e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VIT_2 PF13757.6 KLO09260.1 - 0.00017 21.4 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.9 KLO09260.1 - 0.0097 16.0 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus PGI PF00342.19 KLO09260.1 - 0.032 12.8 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoglucose isomerase DUF2201 PF09967.9 KLO09260.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 VWA-like domain (DUF2201) RabGAP-TBC PF00566.18 KLO09262.1 - 3.8e-46 157.5 0.0 5.4e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FAD_binding_4 PF01565.23 KLO09263.1 - 1.3e-09 37.9 1.1 2.1e-09 37.2 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain VWA PF00092.28 KLO09263.1 - 2.6e-06 27.8 0.5 0.012 15.8 0.2 2.5 1 1 1 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KLO09263.1 - 0.0013 19.3 0.0 0.019 15.6 0.0 2.7 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF5480 PF17576.2 KLO09264.1 - 0.008 16.1 0.2 0.014 15.3 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5480) FAD_binding_4 PF01565.23 KLO09265.1 - 1.8e-24 86.1 0.3 3.3e-24 85.2 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Sigma70_ner PF04546.13 KLO09265.1 - 0.0025 17.7 1.6 0.15 11.9 1.3 2.6 3 0 0 3 3 3 2 Sigma-70, non-essential region BBE PF08031.12 KLO09265.1 - 0.008 16.3 0.1 0.018 15.1 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like ADH_zinc_N PF00107.26 KLO09266.1 - 9.9e-28 96.7 0.0 1.7e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO09266.1 - 1.5e-17 64.9 0.0 3e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO09266.1 - 1.7e-05 24.7 0.0 0.0073 16.2 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain CMAS PF02353.20 KLO09266.1 - 0.016 14.6 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ADH_N_2 PF16884.5 KLO09266.1 - 0.018 15.0 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase adh_short PF00106.25 KLO09266.1 - 0.039 13.4 0.1 0.065 12.7 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase PA PF02225.22 KLO09266.1 - 0.05 13.6 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 PA domain DUF2431 PF10354.9 KLO09267.1 - 2.4e-50 171.1 0.0 3.4e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) RAMP4 PF06624.12 KLO09268.1 - 4.6e-19 68.2 0.0 5.1e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 CAF1C_H4-bd PF12265.8 KLO09269.1 - 1.6e-27 95.5 1.4 3.9e-27 94.3 0.9 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KLO09269.1 - 3.6e-20 71.9 5.6 4.7e-06 27.2 0.2 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO09269.1 - 0.00052 20.3 0.0 0.015 15.6 0.0 3.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain ATP-synt_E PF05680.12 KLO09270.1 - 3.3e-18 65.8 0.2 3.7e-18 65.6 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF2663 PF10864.8 KLO09270.1 - 0.022 15.2 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) BRCA-2_OB1 PF09103.10 KLO09271.1 - 1.2e-35 122.2 0.0 7.6e-34 116.3 0.0 2.3 2 0 0 2 2 2 2 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 KLO09271.1 - 9.7e-08 31.9 0.6 4.4e-06 26.5 0.6 2.7 2 1 1 3 3 3 1 BRCA2, helical UDPGP PF01704.18 KLO09272.1 - 4.9e-40 137.4 0.0 7.7e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Taxilin PF09728.9 KLO09273.1 - 2e-15 56.8 41.5 2.1e-10 40.3 22.4 2.9 2 1 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.8 KLO09273.1 - 0.00093 19.0 0.1 0.64 9.9 0.0 3.2 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like DUF4094 PF13334.6 KLO09273.1 - 0.27 11.7 9.8 3.5 8.1 5.2 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) CENP-F_leu_zip PF10473.9 KLO09273.1 - 4.5 7.3 38.0 0.23 11.5 16.6 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADH_zinc_N PF00107.26 KLO09276.1 - 2.1e-25 89.2 0.0 3.3e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO09276.1 - 8.3e-18 65.7 0.0 1.6e-17 64.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO09276.1 - 1.4e-06 28.1 0.0 0.00014 21.7 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain FUN14 PF04930.15 KLO09276.1 - 0.055 13.9 0.0 1.8 9.0 0.0 2.7 3 0 0 3 3 3 0 FUN14 family CMAS PF02353.20 KLO09276.1 - 0.092 12.0 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TrkA_N PF02254.18 KLO09276.1 - 0.097 12.9 0.0 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain DUF5127 PF17168.4 KLO09278.1 - 1e-53 182.4 3.9 1.5e-53 181.9 2.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO09278.1 - 1.9e-47 161.2 0.2 3.8e-47 160.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO09278.1 - 2.9e-34 118.9 0.0 5.6e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO09278.1 - 1.8e-08 33.8 0.3 5.1e-08 32.3 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KLO09278.1 - 0.0017 17.9 0.2 0.0028 17.2 0.2 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Sad1_UNC PF07738.13 KLO09279.1 - 2.1e-06 27.7 0.0 0.0026 17.8 0.0 2.1 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 KLO09279.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain ANAPC10 PF03256.16 KLO09279.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) zf-C2H2 PF00096.26 KLO09281.1 - 5.5e-10 39.2 17.4 7.5e-05 23.0 4.3 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KLO09281.1 - 7.5e-07 29.3 2.6 7.5e-07 29.3 2.6 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KLO09281.1 - 0.032 15.1 3.8 0.032 15.1 3.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KLO09281.1 - 2.7 7.9 9.8 12 5.7 1.7 3.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KLO09281.1 - 8 6.3 9.6 1.4 8.8 2.8 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF2235 PF09994.9 KLO09282.1 - 5e-92 308.3 6.7 1.6e-91 306.7 6.7 1.8 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) KBP_C PF12309.8 KLO09282.1 - 0.72 9.3 6.1 1.2 8.6 6.1 1.2 1 0 0 1 1 1 0 KIF-1 binding protein C terminal DUF3176 PF11374.8 KLO09283.1 - 0.09 13.0 1.7 0.23 11.7 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) MyTH4 PF00784.17 KLO09289.1 - 0.019 15.4 1.1 0.028 14.9 1.1 1.5 1 1 0 1 1 1 0 MyTH4 domain DUF2206 PF09971.9 KLO09291.1 - 0.19 10.4 0.1 0.26 10.0 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) tRNA-synt_1c PF00749.21 KLO09292.1 - 0.084 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Pox_M2 PF04887.12 KLO09294.1 - 0.00027 20.5 0.0 0.00036 20.1 0.0 1.2 1 0 0 1 1 1 1 Poxvirus M2 protein HTH_ABP1_N PF18107.1 KLO09294.1 - 0.025 14.3 0.1 0.06 13.1 0.1 1.6 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain CRM1_repeat_2 PF18784.1 KLO09295.1 - 0.08 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 ETRAMP PF09716.10 KLO09295.1 - 0.14 12.2 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Lipase_3 PF01764.25 KLO09300.1 - 3e-16 59.6 0.0 4.3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KLO09300.1 - 0.00095 19.8 0.0 0.0014 19.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KLO09300.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) APOBEC4 PF18775.1 KLO09301.1 - 1.7 8.8 4.6 7.6 6.8 0.2 3.0 3 1 1 4 4 4 0 APOBEC4 p450 PF00067.22 KLO09304.1 - 8.3e-59 199.5 0.0 1.1e-58 199.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 peroxidase PF00141.23 KLO09305.1 - 2.7e-27 96.0 0.0 5.2e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KLO09305.1 - 1.2e-24 86.1 2.2 1.2e-24 86.1 2.2 1.8 2 0 0 2 2 2 1 Fungal peroxidase extension region p450 PF00067.22 KLO09308.1 - 1.1e-60 205.8 0.0 1.5e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KLO09309.1 - 2.6e-07 30.4 0.0 6.6e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09309.1 - 0.0086 15.9 0.1 0.024 14.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain DUF3450 PF11932.8 KLO09311.1 - 0.0026 17.1 0.2 0.0027 17.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Snapin_Pallidin PF14712.6 KLO09311.1 - 0.0034 17.8 0.1 0.0043 17.4 0.1 1.2 1 0 0 1 1 1 1 Snapin/Pallidin ADIP PF11559.8 KLO09311.1 - 0.0054 16.8 0.2 0.0065 16.6 0.2 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Nsp1_C PF05064.13 KLO09311.1 - 0.0073 16.1 0.6 0.0087 15.9 0.6 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region CENP-F_leu_zip PF10473.9 KLO09311.1 - 0.033 14.2 2.7 0.033 14.2 1.7 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KLO09311.1 - 0.039 14.5 1.3 0.047 14.2 1.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 KLO09311.1 - 0.042 13.9 0.6 0.063 13.3 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KLO09311.1 - 0.059 13.2 1.4 0.065 13.0 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Lectin_N PF03954.14 KLO09311.1 - 0.11 12.3 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain YabA PF06156.13 KLO09311.1 - 0.17 12.5 1.1 0.31 11.7 1.2 1.4 1 1 0 1 1 1 0 Initiation control protein YabA F-box-like PF12937.7 KLO09312.1 - 1.1e-09 38.1 0.6 5.3e-08 32.6 0.0 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO09312.1 - 0.0011 18.8 0.1 0.078 12.9 0.0 2.9 2 0 0 2 2 2 1 F-box domain Cation_efflux PF01545.21 KLO09314.1 - 4.1e-53 180.1 0.0 6.5e-53 179.4 0.0 1.3 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KLO09314.1 - 0.017 15.3 1.1 0.033 14.3 1.1 1.4 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter Med5 PF08689.10 KLO09315.1 - 1.1e-09 36.7 2.1 1.1e-09 36.7 2.1 1.7 2 0 0 2 2 2 1 Mediator complex subunit Med5 Nop10p PF04135.12 KLO09316.1 - 7.6e-22 77.1 0.2 8.9e-22 76.9 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Phytoreo_S7 PF07236.11 KLO09316.1 - 0.14 10.5 0.0 0.15 10.4 0.0 1.0 1 0 0 1 1 1 0 Phytoreovirus S7 protein Pro_isomerase PF00160.21 KLO09317.1 - 2e-43 148.4 0.0 3.1e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KLO09317.1 - 0.0063 16.7 0.3 0.091 13.0 0.0 2.5 2 1 0 2 2 2 1 U-box domain Rtf2 PF04641.12 KLO09317.1 - 0.031 13.6 1.8 0.12 11.7 0.1 2.3 2 1 0 2 2 2 0 Rtf2 RING-finger zf-NOSIP PF15906.5 KLO09317.1 - 0.069 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein HK_sensor PF16750.5 KLO09317.1 - 0.14 12.5 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 Sensor domain of 2-component histidine kinase Asp PF00026.23 KLO09318.1 - 7.4e-52 176.7 7.6 1.9e-51 175.3 7.6 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO09318.1 - 4.4e-10 40.1 8.0 0.00012 22.3 0.3 2.8 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KLO09318.1 - 0.0012 18.6 0.0 0.0042 16.9 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KLO09318.1 - 0.0013 19.4 1.6 0.0065 17.1 0.4 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KLO09318.1 - 0.06 13.9 0.3 0.17 12.5 0.1 1.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 KLO09319.1 - 4.8e-39 134.6 8.6 2.7e-38 132.2 8.6 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO09319.1 - 1.8e-08 34.8 5.7 1.6e-05 25.2 0.2 2.7 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal F-box PF00646.33 KLO09320.1 - 2.2e-06 27.4 0.3 5.4e-06 26.1 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO09320.1 - 0.00031 20.6 0.4 0.00075 19.3 0.4 1.7 1 0 0 1 1 1 1 F-box-like SMAP PF15477.6 KLO09320.1 - 0.026 15.5 0.1 0.22 12.5 0.0 2.5 2 0 0 2 2 2 0 Small acidic protein family BMFP PF04380.13 KLO09320.1 - 0.055 13.9 0.2 0.27 11.8 0.0 2.1 2 0 0 2 2 2 0 Membrane fusogenic activity F-box PF00646.33 KLO09321.1 - 5.3e-05 23.0 0.3 0.00014 21.6 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO09321.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 F-box-like TF_Zn_Ribbon PF08271.12 KLO09321.1 - 6.2 6.4 5.8 29 4.3 0.3 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding Ribul_P_3_epim PF00834.19 KLO09322.1 - 7.9e-63 211.4 0.1 9.4e-63 211.2 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 KLO09322.1 - 0.032 14.0 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Gly_transf_sug PF04488.15 KLO09323.1 - 8.4e-06 26.3 0.0 1.8e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KLO09323.1 - 0.045 13.1 0.2 0.071 12.5 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein ABC2_membrane PF01061.24 KLO09323.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 ABC-2 type transporter PK PF00224.21 KLO09324.1 - 3.2e-167 555.7 0.5 4.2e-167 555.4 0.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KLO09324.1 - 7.9e-39 132.5 0.0 3.7e-38 130.4 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KLO09324.1 - 9e-05 21.7 0.4 0.00027 20.2 0.4 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KLO09324.1 - 0.00079 18.5 0.0 0.0064 15.5 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain LAG1-DNAbind PF09271.11 KLO09325.1 - 3.3e-26 92.7 0.7 1.5e-23 84.1 0.7 2.2 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 KLO09325.1 - 4.3e-22 79.0 0.0 9.4e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF4203 PF13886.6 KLO09329.1 - 5.5e-51 173.1 29.8 5.5e-51 173.1 29.8 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4203) Mucin PF01456.17 KLO09329.1 - 2.5 8.1 35.6 0.015 15.3 26.6 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein DEAD PF00270.29 KLO09330.1 - 4e-20 72.3 0.0 6.7e-19 68.3 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO09330.1 - 0.00088 19.6 0.0 0.0024 18.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO09330.1 - 0.0027 17.7 0.0 0.0063 16.5 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RNase_PH PF01138.21 KLO09331.1 - 1.2e-18 67.8 0.9 1.7e-18 67.4 0.9 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Sugar_tr PF00083.24 KLO09332.1 - 2.6e-111 372.7 16.3 2.9e-111 372.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO09332.1 - 7.5e-33 113.9 44.4 5.1e-27 94.7 23.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO09333.1 - 2.1e-107 359.8 15.0 2.6e-107 359.5 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO09333.1 - 1.5e-28 99.8 44.1 2.1e-27 96.0 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box PF00646.33 KLO09335.1 - 1.6e-05 24.7 0.3 1.6e-05 24.7 0.3 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KLO09335.1 - 0.053 13.4 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 F-box-like DAO PF01266.24 KLO09336.1 - 1.2e-63 215.9 1.6 1.3e-63 215.7 1.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO09336.1 - 0.00017 21.8 0.6 0.00065 19.9 0.4 2.0 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO09336.1 - 0.001 18.3 0.4 0.056 12.7 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO09336.1 - 0.0026 17.0 0.7 0.0048 16.2 0.7 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KLO09336.1 - 0.026 15.1 0.4 0.052 14.1 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KLO09336.1 - 0.034 13.0 0.1 0.051 12.4 0.1 1.3 1 0 0 1 1 1 0 MCRA family Trp_halogenase PF04820.14 KLO09336.1 - 0.15 10.8 0.8 0.19 10.5 0.8 1.3 1 1 0 1 1 1 0 Tryptophan halogenase Enolase_C PF00113.22 KLO09337.1 - 2.9e-147 489.6 0.1 4e-147 489.2 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KLO09337.1 - 2.9e-58 195.7 0.1 6.4e-58 194.6 0.1 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KLO09337.1 - 0.00087 18.9 0.0 0.0018 17.9 0.0 1.5 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KLO09337.1 - 0.023 13.8 0.4 0.057 12.6 0.4 1.6 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus zf-MYND PF01753.18 KLO09338.1 - 2.3e-07 30.8 13.8 5.7e-07 29.5 13.8 1.7 1 0 0 1 1 1 1 MYND finger Snf7 PF03357.21 KLO09339.1 - 2e-38 131.7 19.3 2.4e-38 131.5 19.3 1.1 1 0 0 1 1 1 1 Snf7 DUF2851 PF11013.8 KLO09339.1 - 0.0095 15.0 4.5 0.011 14.7 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2851) RbsD_FucU PF05025.13 KLO09339.1 - 0.14 12.6 4.0 0.11 13.0 1.5 2.0 1 1 1 2 2 2 0 RbsD / FucU transport protein family SRPRB PF09439.10 KLO09340.1 - 6.9 6.1 6.8 15 5.0 6.8 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-RING_2 PF13639.6 KLO09341.1 - 1e-11 44.9 4.6 2e-11 44.0 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KLO09341.1 - 1.5e-10 41.2 3.7 3.5e-10 40.0 3.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KLO09341.1 - 2.4e-08 33.7 5.5 6.8e-08 32.2 5.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KLO09341.1 - 1.7e-06 27.7 1.6 3.6e-06 26.6 1.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KLO09341.1 - 2.4e-06 27.3 3.5 2.4e-06 27.3 3.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO09341.1 - 9.8e-06 25.5 3.6 2.3e-05 24.3 3.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KLO09341.1 - 1.6e-05 24.8 2.0 1.6e-05 24.8 2.0 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KLO09341.1 - 2.3e-05 24.3 0.4 4.3e-05 23.5 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KLO09341.1 - 0.00014 21.7 1.5 0.00014 21.7 1.5 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO09341.1 - 0.0024 17.7 3.8 0.0044 16.8 3.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KLO09341.1 - 0.028 14.0 2.5 0.06 13.0 2.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KLO09341.1 - 0.21 11.8 3.5 0.88 9.8 3.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zinc_ribbon_9 PF14369.6 KLO09341.1 - 0.25 11.7 0.1 0.25 11.7 0.1 2.4 3 0 0 3 3 2 0 zinc-ribbon zf-RING_4 PF14570.6 KLO09341.1 - 0.41 10.5 2.9 0.81 9.5 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KLO09341.1 - 0.5 10.7 3.0 1.8 9.0 3.0 1.9 1 1 0 1 1 1 0 RING-like domain PHD PF00628.29 KLO09341.1 - 0.76 9.7 8.0 0.038 13.9 2.6 1.6 2 0 0 2 2 1 0 PHD-finger zf-C3HC4_4 PF15227.6 KLO09341.1 - 1.5 9.0 4.2 4.1 7.6 4.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 KLO09341.1 - 2.2 8.4 4.7 0.97 9.6 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Prok-RING_1 PF14446.6 KLO09341.1 - 3.8 7.5 10.4 0.37 10.8 3.7 2.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 Dicty_REP PF05086.12 KLO09341.1 - 7.4 4.4 9.4 10 4.0 9.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DNA_RNApol_7kD PF03604.13 KLO09342.1 - 0.16 11.7 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.10 KLO09342.1 - 0.27 11.4 1.0 6.6 6.9 0.6 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Phasin_2 PF09361.10 KLO09344.1 - 0.072 13.4 2.2 0.49 10.7 0.1 2.1 2 0 0 2 2 2 0 Phasin protein DGF-1_C PF11040.8 KLO09344.1 - 0.13 12.2 6.8 2.5 8.1 2.0 2.5 2 1 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus zf-C2H2 PF00096.26 KLO09347.1 - 1.6e-08 34.5 10.0 2.2e-06 27.8 2.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KLO09347.1 - 1e-06 28.9 13.1 7.6e-05 23.0 4.2 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KLO09347.1 - 0.0014 19.2 9.0 0.0041 17.8 1.7 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 KLO09347.1 - 0.006 17.2 4.2 0.77 10.4 0.8 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain Rad50_zn_hook PF04423.14 KLO09347.1 - 0.0086 15.9 0.3 0.047 13.5 0.1 2.0 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-C2H2_11 PF16622.5 KLO09347.1 - 0.019 14.7 0.7 0.038 13.8 0.7 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KLO09347.1 - 0.028 14.2 0.7 0.039 13.8 0.1 1.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 KLO09347.1 - 0.035 14.5 3.0 0.19 12.2 0.3 2.4 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KLO09347.1 - 0.14 12.5 5.2 0.21 11.9 5.2 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF2225 PF09986.9 KLO09347.1 - 0.41 10.3 1.9 0.42 10.3 1.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) COMP PF11598.8 KLO09349.1 - 0.066 13.7 0.5 0.16 12.4 0.5 1.6 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein LIME1 PF15332.6 KLO09352.1 - 0.4 10.3 3.4 0.53 9.9 3.4 1.1 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 Retinal PF15449.6 KLO09354.1 - 0.0099 13.7 1.1 0.011 13.6 1.1 1.0 1 0 0 1 1 1 1 Retinal protein SMN PF06003.12 KLO09355.1 - 8.5e-05 21.9 1.4 0.00024 20.5 1.1 1.8 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) DUF4808 PF16066.5 KLO09367.1 - 3.5 8.2 5.8 0.5 10.9 1.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4808) Glyco_hydro_20 PF00728.22 KLO09376.1 - 3.6e-90 302.9 0.0 4.4e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KLO09376.1 - 5.6e-19 69.2 0.0 1.2e-18 68.1 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KLO09376.1 - 5.2e-07 30.5 0.3 2e-05 25.4 0.1 2.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Pkinase PF00069.25 KLO09377.1 - 0.005 16.2 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 KLO09377.1 - 0.018 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KLO09377.1 - 0.024 14.2 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KLO09382.1 - 9e-38 130.1 0.0 1.2e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO09382.1 - 1.6e-36 125.9 0.0 2.4e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KLO09382.1 - 0.00056 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KLO09382.1 - 0.048 13.0 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CCD48 PF15799.5 KLO09382.1 - 0.14 10.4 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 DUF3176 PF11374.8 KLO09383.1 - 0.035 14.3 4.6 0.099 12.9 4.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) DUF975 PF06161.11 KLO09383.1 - 0.061 13.1 2.2 0.11 12.2 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF975) DUF3176 PF11374.8 KLO09384.1 - 0.58 10.4 3.4 0.65 10.2 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) NicO PF03824.16 KLO09387.1 - 0.018 14.4 1.0 0.018 14.4 1.0 2.6 2 1 1 3 3 3 0 High-affinity nickel-transport protein SLATT_5 PF18160.1 KLO09387.1 - 8.2 5.7 6.9 7.5 5.8 4.6 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF4006 PF13179.6 KLO09390.1 - 0.095 12.6 0.2 11 6.0 0.3 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Comm PF15957.5 KLO09390.1 - 0.34 11.2 2.6 9.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Commissureless TssN PF17555.2 KLO09390.1 - 3.2 7.1 11.5 1.7 8.0 5.4 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN COX1 PF00115.20 KLO09390.1 - 7.5 5.3 13.2 2 7.2 1.2 3.0 2 2 2 4 4 4 0 Cytochrome C and Quinol oxidase polypeptide I Exotox-A_bind PF09101.10 KLO09393.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Exotoxin A binding Pkinase PF00069.25 KLO09395.1 - 1.9e-40 138.9 0.0 2.1e-32 112.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO09395.1 - 1.2e-25 90.3 0.0 2e-23 83.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 KLO09395.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KLO09395.1 - 0.18 10.9 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KLO09395.1 - 0.22 10.3 3.7 0.4 9.4 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase ChiW_Ig_like PF18683.1 KLO09396.1 - 0.073 13.3 0.1 0.073 13.3 0.1 1.7 2 0 0 2 2 2 0 Chitinase W immunoglobulin-like domain RPAP1_C PF08620.10 KLO09399.1 - 8.5e-20 70.6 0.0 1.7e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KLO09399.1 - 1.5e-05 24.7 2.6 1.5e-05 24.7 2.6 1.9 2 0 0 2 2 2 1 RPAP1-like, N-terminal Methyltransf_2 PF00891.18 KLO09400.1 - 4.4e-20 71.9 0.0 5.2e-19 68.4 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KLO09400.1 - 0.00091 19.9 0.0 0.0033 18.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KLO09400.1 - 0.0051 16.4 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KLO09400.1 - 0.0071 17.0 0.0 0.017 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KLO09400.1 - 0.053 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase tRNA-synt_1c PF00749.21 KLO09401.1 - 1.3e-102 342.9 0.1 1.7e-102 342.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KLO09401.1 - 2.2e-36 125.4 0.5 1.8e-35 122.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 KLO09401.1 - 0.00033 20.6 0.1 0.00099 19.1 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AIMP2_LysRS_bd PF16780.5 KLO09401.1 - 0.00042 20.0 0.0 0.00088 19.0 0.0 1.6 1 0 0 1 1 1 1 AIMP2 lysyl-tRNA synthetase binding domain GST_C PF00043.25 KLO09401.1 - 0.011 15.9 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KLO09401.1 - 0.045 13.1 0.3 0.079 12.3 0.3 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Rad52_Rad22 PF04098.15 KLO09402.1 - 7.9e-59 198.0 0.0 9.1e-59 197.8 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein F-box-like PF12937.7 KLO09404.1 - 6.1e-07 29.2 0.5 2.5e-06 27.3 0.5 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09404.1 - 6.4e-07 29.1 0.5 1.6e-06 27.9 0.5 1.7 1 0 0 1 1 1 1 F-box domain Ribosomal_L14e PF01929.17 KLO09406.1 - 1.3e-33 115.3 0.7 3.3e-33 114.0 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 KLO09406.1 - 0.0001 22.1 0.1 0.0001 22.1 0.1 1.8 2 1 1 3 3 3 1 KOW motif Amidase PF01425.21 KLO09407.1 - 4.2e-89 299.6 0.0 6e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 Amidase Kinetochor_Ybp2 PF08568.10 KLO09408.1 - 1.5e-26 93.1 1.0 8.2e-20 70.8 0.1 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Bestrophin PF01062.21 KLO09409.1 - 7.2e-37 127.4 0.8 2.6e-19 69.7 0.2 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel SET PF00856.28 KLO09410.1 - 1.7e-12 48.0 0.0 7.1e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KLO09410.1 - 2.3e-08 34.0 17.3 2.3e-08 34.0 17.3 2.8 2 1 0 2 2 2 1 MYND finger ATXN-1_C PF12547.8 KLO09410.1 - 0.087 13.2 3.4 0.37 11.2 0.2 2.8 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator Kdo PF06293.14 KLO09412.1 - 0.025 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PCC_BT PF18140.1 KLO09413.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain Kdo PF06293.14 KLO09417.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kdo PF06293.14 KLO09419.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KLO09419.1 - 0.051 12.9 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain AA_permease_2 PF13520.6 KLO09420.1 - 4.3e-68 230.1 37.7 5.5e-68 229.7 37.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KLO09420.1 - 5.2e-18 64.9 30.1 7.1e-18 64.5 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease Phage_holin_2_2 PF10746.9 KLO09420.1 - 1.4 8.7 4.2 1.2 8.8 0.8 2.4 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II CH PF00307.31 KLO09421.1 - 2.7e-77 256.0 0.0 7e-20 71.2 0.0 4.8 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KLO09421.1 - 1.2e-05 25.1 0.0 7.3 6.5 0.0 4.9 5 0 0 5 5 5 3 CAMSAP CH domain Fucose_iso_N1 PF07881.12 KLO09421.1 - 0.1 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain CKAP2_C PF15297.6 KLO09421.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus TFIIA_gamma_C PF02751.14 KLO09422.1 - 5.3e-23 80.9 0.5 8.3e-23 80.3 0.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KLO09422.1 - 1.9e-16 59.8 0.7 2.8e-16 59.3 0.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Na_Ca_ex PF01699.24 KLO09423.1 - 7.1e-36 123.4 36.0 6.1e-19 68.5 14.3 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein ThiS PF02597.20 KLO09427.1 - 2.6e-07 31.2 0.0 3.4e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 ThiS family zf-C2H2_4 PF13894.6 KLO09428.1 - 0.14 13.0 3.9 2.7 9.1 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KLO09428.1 - 0.78 10.3 7.1 3.2 8.4 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.26 KLO09428.1 - 1.1 9.9 8.8 2.6 8.7 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KLO09429.1 - 0.0011 19.0 0.6 0.0029 17.6 0.0 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KLO09429.1 - 0.073 13.9 3.4 0.8 10.7 0.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO09429.1 - 0.28 11.7 4.8 1.3 9.6 1.0 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KLO09429.1 - 4.1 7.2 5.0 5.1 6.9 0.2 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type p450 PF00067.22 KLO09430.1 - 1.5e-56 192.1 0.0 1e-55 189.3 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 DUF1769 PF08588.10 KLO09431.1 - 9.2e-24 83.4 0.1 1.6e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) zf-C5HC2 PF02928.16 KLO09432.1 - 0.031 14.7 0.2 3.7 8.0 0.0 2.3 2 0 0 2 2 2 0 C5HC2 zinc finger RNase_H PF00075.24 KLO09436.1 - 0.00011 22.4 0.0 0.00014 22.0 0.0 1.2 1 0 0 1 1 1 1 RNase H zf-C2H2_4 PF13894.6 KLO09437.1 - 0.0079 16.9 4.0 0.75 10.8 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO09437.1 - 1.7 9.3 8.4 6.5 7.4 1.4 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Condensation PF00668.20 KLO09438.1 - 0.00029 19.6 0.0 0.00041 19.2 0.0 1.2 1 0 0 1 1 1 1 Condensation domain ANAPC4_WD40 PF12894.7 KLO09440.1 - 2.2e-12 47.1 0.3 0.024 14.9 0.1 4.9 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KLO09440.1 - 5.5e-12 46.0 9.2 0.0013 19.5 0.2 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KLO09440.1 - 0.00086 18.4 0.0 0.26 10.2 0.0 2.7 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PGI PF00342.19 KLO09441.1 - 3.6e-231 767.9 0.2 4.1e-231 767.7 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4451 PF14616.6 KLO09443.1 - 1.6e-07 31.6 17.9 0.07 13.3 7.3 5.2 4 1 1 5 5 5 4 Domain of unknown function (DUF4451) Transcrip_act PF04949.13 KLO09445.1 - 0.0003 20.7 2.9 0.079 12.8 2.1 2.2 1 1 1 2 2 2 2 Transcriptional activator DUF2353 PF09789.9 KLO09445.1 - 0.0033 16.8 2.0 0.004 16.6 2.0 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Apolipoprotein PF01442.18 KLO09445.1 - 0.011 15.6 2.9 0.032 14.1 2.9 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2408 PF10303.9 KLO09445.1 - 0.019 15.5 1.1 0.035 14.7 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF1640 PF07798.11 KLO09445.1 - 0.022 14.8 3.8 0.027 14.5 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Prefoldin_2 PF01920.20 KLO09445.1 - 0.031 14.2 2.9 1.6 8.8 0.0 2.4 1 1 1 2 2 2 0 Prefoldin subunit LMP PF04778.12 KLO09445.1 - 0.044 13.7 1.0 0.063 13.2 1.0 1.2 1 0 0 1 1 1 0 LMP repeated region tRNA-synt_2e PF02091.15 KLO09445.1 - 0.061 12.6 0.4 0.075 12.3 0.4 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit 6PF2K PF01591.18 KLO09445.1 - 0.066 12.5 0.5 0.11 11.8 0.3 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase CHAT PF12770.7 KLO09446.1 - 1.6e-28 100.0 0.0 2e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 CHAT domain TSSC4 PF15264.6 KLO09446.1 - 0.033 14.5 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 PhdYeFM_antitox PF02604.19 KLO09446.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system CHAT PF12770.7 KLO09450.1 - 3e-28 99.1 0.0 5.3e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TSSC4 PF15264.6 KLO09450.1 - 0.071 13.4 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 PCI PF01399.27 KLO09452.1 - 6.8e-05 23.3 0.0 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain LtrA PF06772.11 KLO09453.1 - 1.2e-06 28.0 10.6 0.00017 20.9 4.1 2.6 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) GWT1 PF06423.12 KLO09453.1 - 0.16 12.1 4.1 22 5.2 0.0 3.9 3 1 0 3 3 3 0 GWT1 XRN1_DBM PF18245.1 KLO09456.1 - 5 7.2 6.1 12 6.0 6.1 1.6 1 0 0 1 1 1 0 5-3 exonuclease XRN1 DCP1-binding motif FSH1 PF03959.13 KLO09457.1 - 5e-46 157.0 0.0 1.2e-45 155.8 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KLO09457.1 - 0.00053 19.7 0.1 0.12 11.9 0.0 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KLO09457.1 - 0.022 14.3 0.0 0.91 8.9 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KLO09457.1 - 0.1 11.8 0.2 3.9 6.7 0.0 2.8 3 0 0 3 3 3 0 Serine aminopeptidase, S33 DLH PF01738.18 KLO09457.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family STE3 PF02076.15 KLO09458.1 - 1.7e-71 240.8 14.0 2e-71 240.6 14.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF5316 PF17247.2 KLO09458.1 - 0.11 12.5 1.3 6.9 6.8 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5316) STE3 PF02076.15 KLO09459.1 - 3.8e-68 229.8 11.2 4.3e-68 229.6 11.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 KLO09460.1 - 5.4e-70 235.9 15.8 6.2e-70 235.7 15.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor PUCC PF03209.15 KLO09460.1 - 0.031 13.3 4.3 1.2 8.0 0.2 2.5 3 0 0 3 3 3 0 PUCC protein STE3 PF02076.15 KLO09461.1 - 7.8e-49 166.4 18.4 1.7e-26 93.1 0.2 2.0 1 1 1 2 2 2 2 Pheromone A receptor DUF423 PF04241.15 KLO09461.1 - 0.11 12.8 0.9 0.27 11.4 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF423) DUF1275 PF06912.11 KLO09462.1 - 2.3e-33 115.7 18.7 2.9e-33 115.4 18.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) RLI PF04068.15 KLO09462.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Possible Fer4-like domain in RNase L inhibitor, RLI STE3 PF02076.15 KLO09464.1 - 3.5e-71 239.8 13.9 4e-71 239.6 13.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF4534 PF15049.6 KLO09464.1 - 0.0033 17.2 1.0 0.0068 16.2 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4534) DUF2157 PF09925.9 KLO09464.1 - 0.029 14.1 0.1 0.029 14.1 0.1 3.2 3 1 1 4 4 4 0 Predicted membrane protein (DUF2157) 7tm_1 PF00001.21 KLO09464.1 - 0.44 9.8 8.8 0.76 9.1 8.8 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) STE3 PF02076.15 KLO09465.1 - 1.2e-58 198.6 16.6 1.4e-58 198.4 16.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 KLO09466.1 - 7.8e-16 58.1 9.1 8.4e-16 58.0 9.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 KLO09467.1 - 2.2e-33 115.7 4.6 2.7e-33 115.4 4.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF5345 PF17280.2 KLO09467.1 - 0.12 12.4 0.5 0.24 11.4 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Abhydrolase_1 PF00561.20 KLO09468.1 - 1.7e-09 37.7 0.1 4.6e-08 33.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO09468.1 - 5.1e-06 27.2 10.6 7e-06 26.8 10.6 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO09468.1 - 0.0035 16.7 0.0 0.0045 16.3 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 STE3 PF02076.15 KLO09469.1 - 4.9e-71 239.3 10.5 5.6e-71 239.1 10.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor NACHT PF05729.12 KLO09471.1 - 3.1e-07 30.5 0.9 1.7e-06 28.1 0.1 2.4 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KLO09471.1 - 6.9e-05 23.3 0.0 0.00019 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KLO09471.1 - 0.00054 19.9 0.0 0.0038 17.2 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KLO09471.1 - 0.0071 16.6 0.2 0.051 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KLO09471.1 - 0.013 15.3 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 KLO09471.1 - 0.014 15.2 0.5 0.042 13.6 0.2 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 KLO09471.1 - 0.018 15.2 0.1 0.041 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KLO09471.1 - 0.025 13.7 0.0 0.063 12.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KLO09471.1 - 0.026 14.9 0.0 0.081 13.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KLO09471.1 - 0.046 13.4 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KLO09471.1 - 0.064 13.7 1.7 0.41 11.1 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SVA PF05326.11 KLO09471.1 - 0.15 12.1 2.2 2.4 8.2 0.2 2.4 1 1 1 2 2 2 0 Seminal vesicle autoantigen (SVA) PhoH PF02562.16 KLO09471.1 - 0.16 11.4 0.1 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 KLO09471.1 - 0.16 12.5 0.0 0.49 10.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KLO09471.1 - 0.17 11.4 0.1 0.4 10.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KLO09472.1 - 4.8e-18 65.2 7.9 5.3e-10 39.7 0.2 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO09472.1 - 9.5e-07 29.0 0.0 0.049 13.9 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KLO09472.1 - 0.0012 18.2 0.0 0.53 9.6 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain PD40 PF07676.12 KLO09472.1 - 0.0016 18.4 0.0 0.57 10.2 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KLO09472.1 - 0.028 13.1 0.0 4.1 5.9 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 KLO09472.1 - 0.063 13.0 0.1 24 4.7 0.0 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PQQ_3 PF13570.6 KLO09472.1 - 0.068 13.7 1.5 7.8 7.1 0.1 2.4 2 0 0 2 2 2 0 PQQ-like domain Amastin PF07344.11 KLO09473.1 - 0.09 12.6 3.9 0.069 13.0 2.1 1.7 2 0 0 2 2 2 0 Amastin surface glycoprotein CcmD PF04995.14 KLO09473.1 - 2.1 8.5 6.4 3.1 8.0 0.9 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Dishevelled PF02377.15 KLO09474.1 - 0.0034 17.9 1.5 0.0041 17.6 0.8 1.6 1 1 0 1 1 1 1 Dishevelled specific domain WD40 PF00400.32 KLO09476.1 - 6.6e-29 99.6 5.8 5.5e-09 36.5 0.2 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO09476.1 - 1.2e-11 44.7 0.0 0.00087 19.5 0.0 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KLO09476.1 - 2.3e-06 27.6 0.0 7.6e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.11 KLO09476.1 - 0.00022 21.1 0.0 0.00049 20.0 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.6 KLO09476.1 - 0.00024 21.5 0.0 0.0008 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain PD40 PF07676.12 KLO09476.1 - 0.0028 17.6 0.0 19 5.3 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ATPase_2 PF01637.18 KLO09476.1 - 0.0083 16.1 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea PQQ_3 PF13570.6 KLO09476.1 - 0.011 16.2 3.0 2.5 8.7 0.1 3.4 3 0 0 3 3 3 0 PQQ-like domain Cytidylate_kin PF02224.18 KLO09476.1 - 0.024 14.4 0.2 0.076 12.7 0.2 1.8 1 0 0 1 1 1 0 Cytidylate kinase APS_kinase PF01583.20 KLO09476.1 - 0.027 14.4 0.1 0.065 13.1 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 KLO09476.1 - 0.029 14.6 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KLO09476.1 - 0.031 14.5 0.1 0.075 13.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KLO09476.1 - 0.066 13.6 1.0 0.15 12.5 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_24 PF13479.6 KLO09476.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytochrom_D1 PF02239.16 KLO09476.1 - 0.089 11.3 0.0 0.16 10.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain fragilysinNterm PF16376.5 KLO09476.1 - 0.11 12.2 0.1 0.36 10.6 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain of fragilysin AAA PF00004.29 KLO09476.1 - 0.13 12.7 1.2 0.78 10.2 0.2 2.9 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF2299 PF10061.9 KLO09476.1 - 0.13 12.0 1.3 2.2 8.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2299) IMD PF08397.11 KLO09479.1 - 0.074 12.4 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_16 PF13191.6 KLO09480.1 - 1.2e-05 25.7 0.0 1.3e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KLO09480.1 - 2.5e-05 24.2 1.5 4.8e-05 23.3 1.5 1.5 1 1 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KLO09480.1 - 0.00052 20.0 0.0 0.00058 19.8 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea APS_kinase PF01583.20 KLO09480.1 - 0.0021 18.0 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 KLO09480.1 - 0.0025 18.1 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KLO09480.1 - 0.0026 17.5 0.1 0.004 16.9 0.1 1.2 1 0 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 KLO09480.1 - 0.0026 17.9 0.1 0.0031 17.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KLO09480.1 - 0.0047 17.3 0.0 0.0067 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 KLO09480.1 - 0.0067 15.6 0.0 0.009 15.2 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.6 KLO09480.1 - 0.015 15.1 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KLO09480.1 - 0.018 14.6 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KLO09480.1 - 0.019 14.5 0.1 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 KLO09480.1 - 0.019 14.7 0.2 0.019 14.7 0.2 1.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KLO09480.1 - 0.022 15.2 0.0 0.042 14.4 0.0 1.3 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 KLO09480.1 - 0.037 14.5 0.0 0.042 14.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KLO09480.1 - 0.053 13.3 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KLO09480.1 - 0.084 12.6 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein PIF1 PF05970.14 KLO09480.1 - 0.15 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 KLO09480.1 - 0.22 10.7 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.32 KLO09481.1 - 1.1e-69 228.6 18.3 2.9e-10 40.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO09481.1 - 1.7e-34 118.0 0.1 0.0013 19.0 0.0 7.1 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KLO09481.1 - 6.6e-15 55.2 0.0 0.031 13.6 0.0 6.6 5 2 1 6 6 6 3 WD40-like domain PD40 PF07676.12 KLO09481.1 - 9.3e-15 54.1 0.0 0.43 10.6 0.0 7.4 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KLO09481.1 - 8.2e-11 41.2 0.0 0.51 8.9 0.0 6.1 3 2 2 6 6 6 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KLO09481.1 - 9.4e-11 41.9 0.0 0.0013 18.7 0.0 3.5 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KLO09481.1 - 1.4e-10 41.1 1.8 1.7e-05 24.5 1.8 4.0 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 KLO09481.1 - 6.8e-09 35.2 0.3 3.9 7.6 0.0 6.9 7 0 0 7 7 7 1 PQQ enzyme repeat Cytochrom_D1 PF02239.16 KLO09481.1 - 1.1e-06 27.4 0.5 0.0068 15.0 0.0 3.5 1 1 4 5 5 5 3 Cytochrome D1 heme domain DsbC_N PF10411.9 KLO09481.1 - 1.6e-06 27.4 2.4 51 3.4 0.0 6.9 7 0 0 7 7 7 0 Disulfide bond isomerase protein N-terminus Proteasome_A_N PF10584.9 KLO09481.1 - 2.4e-06 27.1 1.0 50 3.7 0.0 7.6 9 0 0 9 9 8 0 Proteasome subunit A N-terminal signature PQQ_3 PF13570.6 KLO09481.1 - 2.6e-06 27.7 7.8 12 6.5 0.0 6.9 6 1 1 7 7 7 0 PQQ-like domain DUF4784 PF16023.5 KLO09481.1 - 9.6e-06 24.8 0.0 0.41 9.5 0.0 4.0 1 1 3 5 5 5 2 Domain of unknown function (DUF4784) DUF5122 PF17164.4 KLO09481.1 - 1.5e-05 25.2 7.8 20 5.6 0.1 7.0 7 0 0 7 7 7 0 Domain of unknown function (DUF5122) beta-propeller nos_propeller PF18764.1 KLO09481.1 - 3.4e-05 23.7 4.6 4.2 7.4 0.0 6.5 6 1 1 7 7 7 1 Nitrous oxide reductase propeller repeat Peptidase_S9_N PF02897.15 KLO09481.1 - 8.9e-05 21.4 0.0 6.1 5.5 0.0 5.2 1 1 6 7 7 7 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Ge1_WD40 PF16529.5 KLO09481.1 - 0.00052 19.1 0.1 28 3.5 0.0 5.3 4 2 1 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ret2_MD PF18528.1 KLO09481.1 - 0.0015 18.9 0.0 44 4.5 0.0 5.4 2 2 5 7 7 7 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Frtz PF11768.8 KLO09481.1 - 0.0064 14.9 0.0 5.7 5.1 0.0 4.1 1 1 5 6 6 6 1 WD repeat-containing and planar cell polarity effector protein Fritz DCX PF03607.17 KLO09481.1 - 0.009 16.1 0.4 1.7e+02 2.4 0.0 5.6 7 0 0 7 7 6 0 Doublecortin Me-amine-dh_H PF06433.11 KLO09481.1 - 0.016 14.1 0.0 3.8 6.3 0.0 3.5 2 2 2 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) DUF5018 PF16410.5 KLO09481.1 - 0.029 13.1 0.0 7.6 5.1 0.0 3.2 1 1 2 4 4 4 0 Domain of unknown function (DUF5018) Nbas_N PF15492.6 KLO09481.1 - 0.047 13.0 0.7 16 4.7 0.0 4.4 5 2 2 7 7 7 0 Neuroblastoma-amplified sequence, N terminal FCP1_C PF09309.10 KLO09481.1 - 0.15 11.9 0.0 3.3 7.5 0.0 2.8 3 1 1 4 4 4 0 FCP1, C-terminal Amastin PF07344.11 KLO09482.1 - 0.019 14.8 2.4 0.022 14.6 1.2 1.7 2 0 0 2 2 2 0 Amastin surface glycoprotein CcmD PF04995.14 KLO09482.1 - 2 8.6 6.4 3.1 8.0 0.9 2.6 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF2269 PF10027.9 KLO09485.1 - 0.7 9.9 9.1 6.1 6.9 3.5 2.5 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF350 PF03994.14 KLO09487.1 - 0.048 13.8 0.9 0.32 11.2 0.1 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF350) Mg_trans_NIPA PF05653.14 KLO09488.1 - 1.8e-18 66.7 20.4 2.5e-11 43.3 6.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KLO09488.1 - 9.2e-05 22.6 9.4 9.2e-05 22.6 9.4 3.5 3 1 0 3 3 3 2 EamA-like transporter family DUF962 PF06127.11 KLO09488.1 - 0.064 13.3 2.7 4.9 7.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF962) SpoIISA_toxin PF14171.6 KLO09488.1 - 0.16 11.7 1.8 0.28 10.9 1.8 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system IFT57 PF10498.9 KLO09488.1 - 2.1 7.2 6.2 16 4.3 2.5 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 TisB_toxin PF13939.6 KLO09490.1 - 0.093 12.5 1.6 0.2 11.5 1.6 1.6 1 0 0 1 1 1 0 Toxin TisB, type I toxin-antitoxin system Mitofilin PF09731.9 KLO09492.1 - 0.019 13.8 21.2 0.025 13.4 21.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Apolipoprotein PF01442.18 KLO09492.1 - 0.02 14.8 14.1 0.039 13.8 14.1 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PRIMA1 PF16101.5 KLO09492.1 - 0.68 10.0 5.6 1.5 8.9 5.6 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Methyltransf_14 PF08484.11 KLO09492.1 - 1 9.2 5.2 0.63 9.8 3.0 1.7 1 1 0 1 1 1 0 C-methyltransferase C-terminal domain U1snRNP70_N PF12220.8 KLO09492.1 - 2.5 8.8 7.5 1.1 9.9 0.5 2.5 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ApoO PF09769.9 KLO09492.1 - 8.3 6.4 6.9 14 5.7 0.8 3.1 1 1 3 4 4 4 0 Apolipoprotein O Hydrolase_like PF13242.6 KLO09493.1 - 6.3e-25 87.0 0.0 1.3e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KLO09493.1 - 2.6e-22 78.9 0.0 4.5e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KLO09493.1 - 2.1e-05 24.9 0.0 0.15 12.4 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KLO09493.1 - 0.027 14.5 0.0 0.64 10.1 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF1768 PF08719.11 KLO09494.1 - 4.4e-32 111.5 0.0 5.2e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.11 KLO09494.1 - 0.013 15.3 0.0 0.15 11.8 0.0 2.1 1 1 0 1 1 1 0 Bacteriophage protein GP30.3 Sec2p PF06428.11 KLO09496.1 - 2e-11 43.7 14.3 2e-11 43.7 14.3 2.7 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p AAA_13 PF13166.6 KLO09496.1 - 0.14 10.8 8.2 0.097 11.3 5.5 1.8 2 0 0 2 2 2 0 AAA domain Spc7 PF08317.11 KLO09496.1 - 0.39 9.6 19.6 2.9 6.7 0.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KLO09496.1 - 1 8.9 8.9 1.4 8.5 3.9 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF5401 PF17380.2 KLO09496.1 - 1.2 7.2 15.6 1.8 6.5 15.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) HIP1_clath_bdg PF16515.5 KLO09496.1 - 3 8.5 23.1 10 6.8 14.8 2.7 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF572 PF04502.13 KLO09496.1 - 5.8 6.4 20.8 13 5.3 15.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF572) Peptidase_M22 PF00814.25 KLO09497.1 - 2e-71 240.9 0.0 2.3e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family GMC_oxred_N PF00732.19 KLO09498.1 - 2.3e-64 217.6 0.0 3.1e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO09498.1 - 1.6e-35 122.7 0.2 2.7e-35 122.0 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KLO09498.1 - 6.1e-05 22.2 0.2 0.00012 21.3 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KLO09498.1 - 0.0002 21.5 0.3 0.0006 20.0 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO09498.1 - 0.00077 19.1 0.4 0.00077 19.1 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO09498.1 - 0.001 18.3 0.5 0.0018 17.5 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KLO09498.1 - 0.0011 18.1 1.6 0.0017 17.5 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KLO09498.1 - 0.009 15.3 0.2 0.074 12.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO09498.1 - 0.011 15.0 0.2 0.024 13.9 0.2 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KLO09498.1 - 0.013 16.0 0.2 0.22 12.1 0.1 2.6 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO09498.1 - 0.016 13.9 0.2 0.033 12.9 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein HHH_2 PF12826.7 KLO09498.1 - 0.054 13.6 0.0 0.22 11.7 0.0 2.1 2 0 0 2 2 1 0 Helix-hairpin-helix motif NAD_binding_9 PF13454.6 KLO09498.1 - 0.089 12.8 0.2 0.54 10.2 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KLO09498.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GMC_oxred_N PF00732.19 KLO09499.1 - 4.1e-61 206.9 0.0 5.4e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO09499.1 - 1.3e-34 119.8 0.1 2.2e-34 119.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KLO09499.1 - 6e-05 22.2 0.0 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KLO09499.1 - 0.00016 21.4 0.3 0.00034 20.3 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO09499.1 - 0.00064 19.9 0.1 0.0024 18.1 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KLO09499.1 - 0.00072 18.8 1.4 0.00083 18.5 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO09499.1 - 0.00096 18.5 0.6 0.0025 17.1 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO09499.1 - 0.004 16.4 0.3 0.0088 15.3 0.3 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KLO09499.1 - 0.042 13.1 0.3 0.36 10.0 0.1 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO09499.1 - 0.064 11.9 0.3 0.16 10.7 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KLO09499.1 - 0.073 13.1 0.2 0.76 9.7 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KLO09499.1 - 0.14 12.4 0.1 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain BTB PF00651.31 KLO09500.1 - 0.00021 21.5 0.0 0.00052 20.2 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Cullin_Nedd8 PF10557.9 KLO09500.1 - 0.31 11.1 0.0 0.31 11.1 0.0 2.1 3 0 0 3 3 3 0 Cullin protein neddylation domain Lipase_3 PF01764.25 KLO09501.1 - 2.5e-13 50.1 0.0 4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Oxidored_FMN PF00724.20 KLO09502.1 - 3.4e-77 260.0 0.0 4e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Rhabdo_NV PF02484.15 KLO09502.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Rhabdovirus Non-virion protein FAD_binding_6 PF00970.24 KLO09512.1 - 0.096 13.0 0.0 0.39 11.1 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Glyoxal_oxid_N PF07250.11 KLO09513.1 - 9.2e-28 97.1 4.0 3.7e-12 46.0 0.1 4.3 3 1 1 4 4 4 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KLO09513.1 - 1.1e-22 80.1 1.0 2e-22 79.3 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Herpes_gE PF02480.16 KLO09513.1 - 0.22 10.2 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kelch_4 PF13418.6 KLO09513.1 - 0.22 11.5 7.9 2.2 8.4 0.2 5.0 6 0 0 6 6 6 0 Galactose oxidase, central domain p450 PF00067.22 KLO09515.1 - 2.3e-74 250.8 0.0 2.6e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MLTR_LBD PF17765.1 KLO09515.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain Tugs PF17840.1 KLO09515.1 - 0.13 12.4 0.2 0.28 11.4 0.2 1.5 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain DUF1129 PF06570.11 KLO09516.1 - 0.0012 18.4 6.7 0.041 13.4 2.8 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1129) DUF485 PF04341.12 KLO09516.1 - 0.024 14.6 0.1 0.024 14.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF485 Fungal_trans PF04082.18 KLO09517.1 - 2.5e-16 59.5 0.2 4.1e-16 58.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO09517.1 - 4.7e-05 23.4 15.3 0.0001 22.3 15.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Matrilin_ccoil PF10393.9 KLO09517.1 - 0.038 13.8 2.2 0.043 13.7 0.6 1.9 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin UQ_con PF00179.26 KLO09518.1 - 6.1e-49 165.3 0.0 6.9e-49 165.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KLO09518.1 - 4.1e-05 23.3 0.0 5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KLO09518.1 - 0.022 14.6 0.1 0.042 13.7 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 KLO09518.1 - 0.08 13.2 0.1 0.098 13.0 0.1 1.5 1 1 0 1 1 1 0 RWD domain Fn_bind PF02986.14 KLO09519.1 - 0.17 11.6 1.2 0.65 9.8 1.2 2.0 1 0 0 1 1 1 0 Fibronectin binding repeat zf-RING_2 PF13639.6 KLO09520.1 - 9.7e-14 51.4 13.2 1.5e-13 50.9 13.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KLO09520.1 - 1.1e-07 31.5 13.0 1.9e-07 30.8 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO09520.1 - 3.8e-07 29.9 8.8 5.7e-07 29.3 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO09520.1 - 4.7e-07 29.7 9.7 8.9e-07 28.8 9.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KLO09520.1 - 7.7e-06 25.7 11.7 1.4e-05 24.8 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KLO09520.1 - 0.0001 22.5 16.7 0.00021 21.5 15.8 1.9 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KLO09520.1 - 0.00014 21.7 9.5 0.00023 21.1 9.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KLO09520.1 - 0.00023 20.9 14.0 0.00068 19.4 7.8 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KLO09520.1 - 0.00025 20.7 5.9 0.00025 20.7 5.9 1.9 2 0 0 2 2 2 1 RING-like zinc finger PHD PF00628.29 KLO09520.1 - 0.0026 17.6 12.5 0.0077 16.1 12.6 1.8 1 1 1 2 2 2 1 PHD-finger RINGv PF12906.7 KLO09520.1 - 0.016 15.3 12.3 0.03 14.5 12.3 1.5 1 0 0 1 1 1 0 RING-variant domain zf-ANAPC11 PF12861.7 KLO09520.1 - 0.02 14.9 9.1 0.039 14.0 9.1 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 KLO09520.1 - 0.033 14.1 7.8 0.033 14.1 7.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 KLO09520.1 - 0.053 13.3 10.8 0.12 12.2 10.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KLO09520.1 - 0.056 13.6 11.9 0.25 11.6 11.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_9 PF13901.6 KLO09520.1 - 0.12 12.3 7.5 0.17 11.8 7.5 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Zf_RING PF16744.5 KLO09520.1 - 0.18 11.9 7.8 0.37 10.9 7.6 1.6 1 1 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 KLO09520.1 - 0.96 9.1 15.4 1.2 8.8 14.8 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rtf2 PF04641.12 KLO09520.1 - 1.4 8.3 3.8 2.8 7.2 3.3 1.7 1 1 0 1 1 1 0 Rtf2 RING-finger DZR PF12773.7 KLO09520.1 - 1.5 8.9 10.7 4.6 7.4 3.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KLO09520.1 - 2.4 8.1 7.3 9.3 6.3 2.4 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain CBM_11 PF03425.13 KLO09525.1 - 0.21 11.4 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) Glyco_transf_6 PF03414.13 KLO09526.1 - 0.02 13.6 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 6 LRR_4 PF12799.7 KLO09529.1 - 0.15 12.5 0.4 26 5.4 0.0 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Epiglycanin_C PF14654.6 KLO09530.1 - 0.00028 20.9 0.2 0.0006 19.8 0.2 1.5 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region Herpes_gE PF02480.16 KLO09530.1 - 0.063 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TPPK_C PF12555.8 KLO09530.1 - 0.95 9.6 3.4 2.7 8.1 1.2 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal 3-HAO PF06052.12 KLO09533.1 - 1.3e-55 187.1 0.0 1.5e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KLO09533.1 - 9.9e-09 34.8 0.1 1.4e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KLO09533.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KLO09533.1 - 0.0065 16.1 0.0 0.0087 15.7 0.0 1.2 1 0 0 1 1 1 1 Cupin F-box-like PF12937.7 KLO09536.1 - 2.2e-06 27.4 0.9 7.5e-06 25.7 0.1 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO09536.1 - 4.8 7.2 9.5 0.78 9.7 0.6 3.2 3 0 0 3 3 3 0 F-box domain Plavaka PF18759.1 KLO09541.1 - 7.5e-119 396.7 0.0 1e-118 396.3 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase PAP2 PF01569.21 KLO09542.1 - 1.8e-28 99.0 1.9 1.8e-28 99.0 0.8 1.5 2 0 0 2 2 2 1 PAP2 superfamily CTD_bind PF04818.13 KLO09543.1 - 0.00052 20.8 0.0 0.0014 19.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. HSF_DNA-bind PF00447.17 KLO09545.1 - 4.6e-33 113.7 1.5 1.1e-32 112.4 1.5 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Actin PF00022.19 KLO09546.1 - 1.1e-111 373.4 0.0 4.3e-101 338.5 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 KLO09546.1 - 0.0028 16.5 0.0 0.014 14.3 0.0 2.0 2 1 0 2 2 2 1 MreB/Mbl protein DNA_pol_lambd_f PF10391.9 KLO09546.1 - 0.066 13.1 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Phos_pyr_kin PF08543.12 KLO09547.1 - 5.8e-10 39.0 0.0 8.4e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KLO09547.1 - 0.0001 21.8 0.0 0.00022 20.7 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase START PF01852.19 KLO09548.1 - 5.6e-22 78.2 0.0 4.8e-12 45.7 0.0 3.7 3 1 0 3 3 3 3 START domain KKLCAg1 PF15204.6 KLO09548.1 - 0.085 13.0 0.2 0.085 13.0 0.2 2.4 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 DUF4451 PF14616.6 KLO09551.1 - 0.0043 17.3 1.3 0.38 10.9 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4451) zf-BED PF02892.15 KLO09551.1 - 0.17 12.0 3.7 12 6.0 1.3 2.5 2 0 0 2 2 2 0 BED zinc finger DUF4451 PF14616.6 KLO09552.1 - 0.023 14.9 0.5 0.28 11.4 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4451) zf-Sec23_Sec24 PF04810.15 KLO09552.1 - 0.033 14.2 0.9 3.3 7.8 0.1 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger SH3_9 PF14604.6 KLO09554.1 - 1.2e-32 111.5 3.2 9e-17 60.7 0.2 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KLO09554.1 - 2.5e-28 97.4 4.1 2.7e-14 52.5 0.4 2.4 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 KLO09554.1 - 7.5e-22 77.4 0.0 1.7e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KLO09554.1 - 3.5e-20 71.5 0.1 4.6e-09 35.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain MliC PF09864.9 KLO09554.1 - 0.039 13.9 0.2 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme RNase_H2_suC PF08615.11 KLO09555.1 - 3.1e-17 63.1 0.0 4.2e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) GPI-anchored PF10342.9 KLO09556.1 - 1.6e-08 35.2 0.3 1.6e-08 35.2 0.3 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PAP1 PF08601.10 KLO09556.1 - 3.6 7.2 16.2 4.5 6.9 16.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 zinc_ribbon_12 PF11331.8 KLO09558.1 - 2.1 8.2 4.8 3.5 7.5 2.3 2.4 2 1 1 3 3 3 0 Probable zinc-ribbon domain zf-CRD PF17979.1 KLO09559.1 - 0.011 15.8 4.7 0.16 12.0 4.7 2.3 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Zn_ribbon_17 PF17120.5 KLO09559.1 - 0.13 11.9 1.7 0.3 10.7 0.2 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF2318 PF10080.9 KLO09559.1 - 0.16 12.1 0.2 3.9 7.6 0.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) zf_UBZ PF18439.1 KLO09559.1 - 0.18 11.4 0.5 7.9 6.2 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-CCHH PF10283.9 KLO09560.1 - 0.026 14.5 6.2 0.19 11.8 6.2 2.2 1 1 0 1 1 1 0 PBZ domain F-box-like PF12937.7 KLO09560.1 - 1 9.3 5.1 5.7 6.9 1.8 2.8 2 0 0 2 2 2 0 F-box-like zf-CCHH PF10283.9 KLO09561.1 - 1.1e-05 25.3 2.7 2.2e-05 24.4 2.7 1.4 1 0 0 1 1 1 1 PBZ domain RNase_H PF00075.24 KLO09562.1 - 3.7e-05 23.9 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 RNase H CNOT1_CAF1_bind PF16415.5 KLO09565.1 - 0.22 10.9 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain zf-CCHH PF10283.9 KLO09565.1 - 0.58 10.2 5.4 1.8 8.6 5.4 2.0 1 1 0 1 1 1 0 PBZ domain Thioredoxin PF00085.20 KLO09566.1 - 4e-21 74.9 0.1 1.6e-20 73.0 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KLO09566.1 - 0.0085 16.5 0.1 0.031 14.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KLO09566.1 - 0.1 12.8 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Trp_ring PF18669.1 KLO09567.1 - 0.22 11.7 0.2 0.49 10.6 0.2 1.5 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain zf-met PF12874.7 KLO09567.1 - 9.9 6.7 6.0 8 7.0 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_clus PF00172.18 KLO09568.1 - 1.3e-24 86.0 85.5 5.1e-07 29.7 13.1 5.7 5 1 1 6 6 6 5 Fungal Zn(2)-Cys(6) binuclear cluster domain zinc-ribbons_6 PF07191.12 KLO09569.1 - 0.028 14.4 1.9 5.3 7.1 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbons Stc1 PF12898.7 KLO09569.1 - 0.65 10.6 5.4 3.7 8.2 0.2 3.1 2 1 0 2 2 2 0 Stc1 domain Glyco_hydro_16 PF00722.21 KLO09570.1 - 2e-07 30.7 0.1 7.7e-07 28.7 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Integrase_H2C2 PF17921.1 KLO09572.1 - 0.0028 17.7 0.1 0.0049 17.0 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC PF00098.23 KLO09575.1 - 0.00042 20.3 2.5 0.00062 19.7 2.5 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 KLO09575.1 - 0.017 15.4 0.1 0.044 14.1 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_3 PF13917.6 KLO09575.1 - 0.047 13.7 1.0 0.083 12.9 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle HTH_23 PF13384.6 KLO09578.1 - 8.6e-09 35.0 0.3 1.5e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KLO09578.1 - 1.8e-08 34.9 0.2 2.4e-08 34.5 0.2 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KLO09578.1 - 4.6e-07 29.8 0.4 2.5e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_33 PF13592.6 KLO09578.1 - 1.1e-05 24.9 0.4 4.8e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_7 PF02796.15 KLO09578.1 - 6.8e-05 22.9 0.0 0.00044 20.3 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.18 KLO09578.1 - 0.00061 20.0 0.1 0.0019 18.4 0.0 1.7 2 0 0 2 2 2 1 Transposase TrmB PF01978.19 KLO09578.1 - 0.0021 17.9 0.0 0.0061 16.4 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_17 PF12728.7 KLO09578.1 - 0.006 16.7 0.2 0.064 13.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KLO09578.1 - 0.0089 15.7 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.6 KLO09578.1 - 0.02 15.0 0.1 0.035 14.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 KLO09578.1 - 0.022 14.7 0.0 8.4 6.4 0.0 2.3 2 0 0 2 2 2 0 HTH domain HTH_IclR PF09339.10 KLO09578.1 - 0.034 13.9 0.0 0.083 12.7 0.0 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF3160 PF11369.8 KLO09579.1 - 0.023 13.2 0.1 0.046 12.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3160) AT_hook PF02178.19 KLO09579.1 - 0.14 12.1 6.9 0.79 9.8 6.9 2.4 1 0 0 1 1 1 0 AT hook motif CTP-dep_RFKase PF01982.16 KLO09579.1 - 0.14 12.3 0.0 0.45 10.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF120 CorA PF01544.18 KLO09580.1 - 1.6 8.0 7.7 0.7 9.2 0.2 2.6 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Astacin PF01400.24 KLO09581.1 - 1.3e-08 34.6 1.6 1.2e-07 31.6 1.4 2.2 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 KLO09581.1 - 0.00012 22.3 0.4 0.00019 21.7 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 KLO09581.1 - 0.00016 21.3 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 KLO09581.1 - 0.0004 20.3 4.3 0.019 14.8 3.1 2.6 2 1 0 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 KLO09581.1 - 0.0015 18.2 1.2 0.0067 16.1 0.1 1.9 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KLO09581.1 - 0.0036 16.6 0.1 0.0068 15.7 0.1 1.4 1 0 0 1 1 1 1 Met-zincin Reprolysin_3 PF13582.6 KLO09581.1 - 0.0063 17.0 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.8 KLO09581.1 - 0.021 14.5 0.2 0.11 12.2 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3152) Peptidase_M66 PF10462.9 KLO09581.1 - 0.023 13.7 0.2 0.042 12.8 0.0 1.6 2 0 0 2 2 2 0 Peptidase M66 DUF3810 PF12725.7 KLO09581.1 - 0.036 13.4 0.2 0.069 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Zincin_1 PF06262.11 KLO09581.1 - 0.2 11.8 0.1 0.4 10.8 0.1 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase Caps_synth_CapC PF14102.6 KLO09582.1 - 4.6 7.7 12.5 0.92 9.9 6.9 2.4 2 1 0 2 2 2 0 Capsule biosynthesis CapC DUF3176 PF11374.8 KLO09583.1 - 0.0023 18.1 1.4 0.0023 18.1 1.4 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3176) DUF2207 PF09972.9 KLO09583.1 - 0.019 13.7 0.4 5.2 5.7 0.0 3.4 4 0 0 4 4 4 0 Predicted membrane protein (DUF2207) Hydrophobin PF01185.18 KLO09584.1 - 2.5e-25 88.9 7.7 2.8e-25 88.8 7.7 1.0 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KLO09586.1 - 2.8e-25 88.8 8.1 3.5e-25 88.5 8.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KLO09587.1 - 7.6e-23 80.9 8.9 1e-22 80.5 8.9 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF2673 PF10880.8 KLO09587.1 - 0.093 12.9 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) ApoL PF05461.11 KLO09587.1 - 0.43 9.8 1.0 0.6 9.4 1.0 1.1 1 0 0 1 1 1 0 Apolipoprotein L Hydrophobin PF01185.18 KLO09588.1 - 7.6e-09 36.1 1.9 1.8e-08 34.9 1.9 1.6 1 1 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KLO09589.1 - 2.6e-13 50.4 3.0 3.3e-13 50.1 3.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KLO09590.1 - 4.9e-20 71.9 7.9 7.3e-20 71.4 7.9 1.3 1 0 0 1 1 1 1 Fungal hydrophobin DPBB_1 PF03330.18 KLO09596.1 - 9.3e-09 35.4 0.0 1.4e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KLO09596.1 - 0.0042 16.9 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Barwin family F-box-like PF12937.7 KLO09599.1 - 0.00044 20.1 0.0 0.0016 18.3 0.0 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09599.1 - 0.11 12.4 6.9 1.4 8.9 0.1 3.3 4 0 0 4 4 4 0 F-box domain WD40 PF00400.32 KLO09600.1 - 2.6e-43 145.2 16.8 1.1e-07 32.4 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO09600.1 - 2e-05 24.8 1.5 0.44 10.9 0.1 5.0 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KLO09600.1 - 0.00073 18.3 1.5 0.36 9.4 0.1 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KLO09600.1 - 0.18 11.1 0.0 0.41 9.9 0.0 1.6 2 0 0 2 2 2 0 WD40-like domain Hydrophobin PF01185.18 KLO09601.1 - 4.4e-11 43.3 7.5 5.5e-11 43.0 7.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DIM1 PF02966.16 KLO09602.1 - 5.8e-67 223.5 0.3 6.6e-67 223.3 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KLO09602.1 - 8.4e-05 22.5 0.1 0.00011 22.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KLO09602.1 - 0.016 15.5 0.8 0.025 14.9 0.7 1.3 1 1 0 1 1 1 0 Thioredoxin-like Thioredox_DsbH PF03190.15 KLO09602.1 - 0.088 12.8 0.6 0.16 11.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 DUF3192 PF11399.8 KLO09602.1 - 0.098 12.6 0.1 0.14 12.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3192) DUF2470 PF10615.9 KLO09603.1 - 6.6e-22 77.9 0.0 1.3e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 KLO09603.1 - 1.1e-11 44.9 1.8 2e-11 44.0 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) GAT PF03127.14 KLO09604.1 - 0.043 14.1 0.2 0.066 13.5 0.2 1.2 1 0 0 1 1 1 0 GAT domain FliJ PF02050.16 KLO09604.1 - 0.13 12.5 8.6 0.18 12.0 8.6 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein DUF5398 PF17376.2 KLO09604.1 - 0.16 12.6 0.1 0.25 12.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5398) PHTB1_C PF14728.6 KLO09604.1 - 0.17 11.0 0.9 0.21 10.6 0.9 1.0 1 0 0 1 1 1 0 PTHB1 C-terminus DUF659 PF04937.15 KLO09607.1 - 0.0058 16.5 0.0 0.0059 16.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4413 PF14372.6 KLO09608.1 - 0.0025 18.2 0.7 0.0031 17.9 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) DNA_topoisoIV PF00521.20 KLO09608.1 - 0.014 14.3 0.2 0.016 14.2 0.2 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A CNOT1_HEAT PF16418.5 KLO09608.1 - 0.091 12.8 0.1 0.19 11.8 0.0 1.5 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Mito_carr PF00153.27 KLO09610.1 - 6.1e-18 64.5 1.2 4.7e-10 39.3 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3180 PF11377.8 KLO09610.1 - 0.38 10.9 4.7 0.37 10.9 2.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3180) DUF5472 PF17566.2 KLO09612.1 - 0.045 13.7 0.1 0.045 13.7 0.1 2.6 3 1 0 3 3 3 0 Family of unknown function (DUF5472) Rhabdo_glycop PF00974.18 KLO09613.1 - 0.11 10.9 0.0 0.12 10.8 0.0 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Pkinase_Tyr PF07714.17 KLO09613.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase BTB PF00651.31 KLO09614.1 - 5.9e-05 23.3 0.0 0.00013 22.1 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain UPF0054 PF02130.17 KLO09614.1 - 0.14 11.9 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 Pcc1 PF09341.10 KLO09615.1 - 0.023 14.9 0.0 0.41 10.8 0.0 2.4 2 0 0 2 2 2 0 Transcription factor Pcc1 PDZ_2 PF13180.6 KLO09615.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 PDZ domain NmrA PF05368.13 KLO09619.1 - 1.5e-18 67.2 0.0 2.6e-18 66.4 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO09619.1 - 4e-08 33.4 0.1 9.8e-08 32.1 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KLO09619.1 - 4.1e-05 23.7 0.1 9.8e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KLO09619.1 - 4.7e-05 23.7 0.4 9.9e-05 22.6 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KLO09619.1 - 0.0026 18.2 0.1 0.0049 17.3 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KLO09619.1 - 0.068 12.2 0.2 0.096 11.7 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KLO09619.1 - 0.088 12.7 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 KR domain Ldh_1_N PF00056.23 KLO09619.1 - 0.091 12.8 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain zf-RRPl_C4 PF17026.5 KLO09620.1 - 0.0021 18.1 0.8 0.0043 17.1 0.8 1.5 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type BTB PF00651.31 KLO09620.1 - 0.0029 17.8 0.5 0.0071 16.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Prok-RING_1 PF14446.6 KLO09620.1 - 0.08 12.9 2.0 0.12 12.3 2.0 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 BTB PF00651.31 KLO09621.1 - 3.6e-13 49.7 0.0 6.7e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain FYVE_2 PF02318.16 KLO09621.1 - 1.7e-05 25.0 0.9 0.0016 18.7 0.4 2.3 2 0 0 2 2 2 2 FYVE-type zinc finger FYVE PF01363.21 KLO09621.1 - 0.39 10.9 8.1 0.98 9.6 1.8 2.7 2 1 1 3 3 2 0 FYVE zinc finger BTB PF00651.31 KLO09622.1 - 3.1e-05 24.2 0.0 5.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Zn-ribbon_8 PF09723.10 KLO09622.1 - 0.0078 16.3 0.3 0.053 13.6 0.0 2.2 2 0 0 2 2 2 1 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KLO09622.1 - 0.012 15.5 0.3 0.023 14.6 0.3 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain BTB PF00651.31 KLO09623.1 - 5.7e-09 36.2 0.0 7.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Ndufs5 PF10200.9 KLO09623.1 - 0.078 13.2 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa BTB PF00651.31 KLO09625.1 - 3e-05 24.2 0.0 5.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.6 KLO09625.1 - 7 6.8 5.9 12 6.0 1.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger BTB PF00651.31 KLO09626.1 - 7.6e-07 29.3 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Zn_Tnp_IS1595 PF12760.7 KLO09626.1 - 0.06 13.3 1.3 0.11 12.4 1.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KLO09626.1 - 0.53 10.2 2.1 1.3 9.0 0.3 1.9 1 1 1 2 2 2 0 Putative transposase DNA-binding domain BTB PF00651.31 KLO09627.1 - 1e-06 28.9 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-NADH-PPase PF09297.11 KLO09627.1 - 0.00011 21.8 0.9 0.011 15.4 0.1 2.4 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain Mut7-C PF01927.16 KLO09627.1 - 0.058 13.5 0.4 0.11 12.6 0.4 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain Terminase_GpA PF05876.12 KLO09627.1 - 0.082 11.4 0.2 0.11 11.0 0.2 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DNA_ligase_ZBD PF03119.16 KLO09627.1 - 0.089 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Ogr_Delta PF04606.12 KLO09627.1 - 0.18 11.8 2.0 11 6.1 0.2 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.10 KLO09627.1 - 1.2 9.4 4.0 7.5 6.8 3.8 2.3 1 1 1 2 2 2 0 Zinc ribbon domain F-box-like PF12937.7 KLO09629.1 - 7.1e-09 35.4 0.7 1.8e-08 34.1 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO09630.1 - 2.4e-09 36.9 0.8 8.7e-09 35.1 0.8 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO09631.1 - 8.5e-08 32.0 1.7 8.5e-08 32.0 1.7 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO09631.1 - 1.3 9.0 6.0 9 6.3 6.0 2.5 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO09632.1 - 9.2e-05 22.3 0.0 0.00025 20.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like TetR_C_33 PF13305.6 KLO09632.1 - 0.099 13.4 0.0 0.52 11.1 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain F-box-like PF12937.7 KLO09633.1 - 1e-09 38.1 0.2 5.6e-09 35.8 0.2 2.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09633.1 - 0.015 15.1 2.6 0.26 11.2 1.4 3.6 3 1 1 4 4 4 0 F-box domain F-box-like PF12937.7 KLO09634.1 - 2.6e-09 36.8 0.1 1.2e-08 34.7 0.1 2.2 2 0 0 2 2 2 1 F-box-like DUF3310 PF11753.8 KLO09634.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) F-box PF00646.33 KLO09634.1 - 0.2 11.6 3.2 0.66 9.9 0.8 3.0 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO09635.1 - 9.7e-10 38.2 0.1 3e-09 36.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like DUF4088 PF13317.6 KLO09635.1 - 0.025 14.1 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) F-box PF00646.33 KLO09635.1 - 0.042 13.7 0.7 15 5.6 0.0 3.3 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO09636.1 - 2.8e-09 36.7 0.1 7.2e-09 35.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09636.1 - 0.015 15.2 0.3 0.058 13.3 0.3 2.0 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO09637.1 - 1e-08 34.9 0.3 2.5e-08 33.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO09638.1 - 1.1e-07 31.6 0.7 1.1e-07 31.6 0.7 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO09638.1 - 0.19 11.7 6.8 0.05 13.5 1.1 3.1 4 0 0 4 4 4 0 F-box domain F-box-like PF12937.7 KLO09639.1 - 1.1e-09 38.1 0.2 3.7e-09 36.3 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09639.1 - 0.034 14.0 0.2 0.12 12.3 0.2 2.0 1 0 0 1 1 1 0 F-box domain zf-C2H2 PF00096.26 KLO09641.1 - 1.4e-13 50.4 12.6 5.8e-07 29.6 5.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO09641.1 - 2.8e-11 43.2 9.2 1.5e-05 25.4 3.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KLO09641.1 - 6.9e-09 35.7 14.9 8e-06 26.1 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KLO09641.1 - 2.5e-06 27.6 3.4 6.4e-05 23.1 0.5 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KLO09641.1 - 1.7e-05 25.1 2.3 0.00011 22.4 0.6 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KLO09641.1 - 2.1e-05 24.3 12.1 0.0031 17.4 3.1 2.7 2 1 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KLO09641.1 - 0.0002 21.3 5.0 0.00049 20.0 1.1 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 KLO09641.1 - 0.0022 18.3 5.2 0.047 14.0 3.8 2.1 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_SprT PF17283.2 KLO09641.1 - 0.0038 17.1 5.4 0.046 13.6 2.1 2.3 1 1 1 2 2 2 1 SprT-like zinc ribbon domain zinc_ribbon_4 PF13717.6 KLO09641.1 - 0.0088 15.9 1.1 0.15 12.0 0.2 2.3 2 1 0 2 2 2 1 zinc-ribbon domain zf-HYPF PF07503.12 KLO09641.1 - 0.017 14.9 2.1 1.6 8.6 0.3 2.3 1 1 1 2 2 2 0 HypF finger zf-C2H2_2 PF12756.7 KLO09641.1 - 0.018 15.3 2.8 0.12 12.7 1.3 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CpXC PF14353.6 KLO09641.1 - 0.02 14.9 1.0 0.53 10.3 0.1 2.0 1 1 1 2 2 2 0 CpXC protein zf-C2H2_11 PF16622.5 KLO09641.1 - 0.027 14.2 4.7 1.1 9.1 1.4 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-DNA_Pol PF08996.10 KLO09641.1 - 0.028 14.1 0.5 0.032 14.0 0.5 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger FOXP-CC PF16159.5 KLO09641.1 - 0.05 14.2 1.0 2.1 9.0 0.0 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 KLO09641.1 - 0.061 13.2 1.1 0.28 11.0 0.2 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_aberr PF17017.5 KLO09641.1 - 0.14 12.3 0.7 0.27 11.4 0.1 1.7 1 1 1 2 2 2 0 Aberrant zinc-finger zf-BED PF02892.15 KLO09641.1 - 0.24 11.4 6.3 12 6.0 6.3 2.2 1 1 0 1 1 1 0 BED zinc finger IBR PF01485.21 KLO09641.1 - 0.28 11.4 4.7 2.1 8.7 0.2 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Cys_rich_CPXG PF14255.6 KLO09641.1 - 0.37 10.7 2.6 11 6.0 0.5 2.7 2 1 1 3 3 3 0 Cysteine-rich CPXCG Zn_Tnp_IS1595 PF12760.7 KLO09641.1 - 0.52 10.3 7.4 1 9.4 6.6 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain FYDLN_acid PF09538.10 KLO09641.1 - 1.2 9.9 3.0 23 5.7 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Totivirus_coat PF05518.11 KLO09644.1 - 3.6 5.5 8.1 3.7 5.5 8.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein Helicase_C PF00271.31 KLO09646.1 - 1.8e-14 54.0 0.0 9.3e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO09646.1 - 3.7e-10 39.9 0.0 1.2e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO09646.1 - 0.00013 22.1 0.1 0.00042 20.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ribosomal_L6e PF01159.19 KLO09646.1 - 3.4 8.2 8.8 1.1 9.9 4.9 2.1 2 0 0 2 2 2 0 Ribosomal protein L6e Flot PF15975.5 KLO09646.1 - 5 7.3 10.0 13 6.0 10.0 1.6 1 0 0 1 1 1 0 Flotillin Atg14 PF10186.9 KLO09646.1 - 6.3 5.8 7.7 10 5.1 7.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Radial_spoke_3 PF06098.11 KLO09646.1 - 7 5.8 19.4 15 4.7 19.4 1.5 1 0 0 1 1 1 0 Radial spoke protein 3 Rho_N PF07498.12 KLO09647.1 - 0.00079 19.3 0.5 0.014 15.3 0.1 2.5 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain BTB PF00651.31 KLO09648.1 - 0.001 19.3 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain PsbK PF02533.15 KLO09648.1 - 0.11 12.6 1.0 0.19 11.9 0.1 1.8 2 0 0 2 2 2 0 Photosystem II 4 kDa reaction centre component NACHT PF05729.12 KLO09665.1 - 5.2e-10 39.5 0.0 1.7e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO09665.1 - 6.3e-07 29.9 0.0 1.7e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KLO09665.1 - 0.016 15.3 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KLO09665.1 - 0.034 14.4 0.0 0.097 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KLO09665.1 - 0.037 14.5 0.0 0.083 13.3 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KLO09665.1 - 0.061 12.5 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 KLO09665.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase tRNA-synt_1g PF09334.11 KLO09666.1 - 1.6e-79 267.5 0.0 5e-78 262.5 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KLO09666.1 - 2.1e-21 75.8 0.2 1.2e-09 37.0 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KLO09666.1 - 9.6e-11 41.6 0.0 0.0001 21.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KLO09666.1 - 9.7e-05 21.4 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) AMP-binding PF00501.28 KLO09667.1 - 2.2e-16 59.5 0.2 3.7e-16 58.8 0.2 1.4 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KLO09667.1 - 1.5e-09 38.7 0.7 2.3e-09 38.1 0.7 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf_CCCH_5 PF18384.1 KLO09668.1 - 0.82 9.8 5.9 0.12 12.5 0.7 2.2 3 0 0 3 3 3 0 Unkempt Zinc finger domain 1 (Znf1) Abhydrolase_3 PF07859.13 KLO09669.1 - 2.8e-14 53.5 0.0 2.1e-12 47.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO09669.1 - 4.4e-07 29.1 0.0 5.8e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KLO09669.1 - 4.6e-07 29.5 0.0 0.015 14.8 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family COesterase PF00135.28 KLO09669.1 - 2.8e-05 23.2 0.0 0.00021 20.3 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 KLO09669.1 - 0.0022 17.3 0.0 0.011 15.0 0.0 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KLO09669.1 - 0.0034 18.0 0.1 0.0079 16.8 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KLO09669.1 - 0.042 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 KLO09669.1 - 0.058 12.9 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF900 PF05990.12 KLO09669.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 KLO09669.1 - 0.2 11.3 0.0 0.57 9.8 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Fungal_trans PF04082.18 KLO09670.1 - 1.2e-13 50.7 0.0 2.2e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO09670.1 - 0.00029 20.9 11.9 0.0006 19.9 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KLO09670.1 - 0.017 13.9 0.0 0.046 12.5 0.0 1.7 1 1 0 1 1 1 0 Fungal specific transcription factor domain Ribonuc_2-5A PF06479.12 KLO09670.1 - 0.14 12.4 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease 2-5A Fungal_trans PF04082.18 KLO09671.1 - 4e-13 49.0 0.0 8.6e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO09671.1 - 4.2e-05 23.6 13.1 7e-05 22.9 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KLO09671.1 - 0.021 13.7 0.4 0.043 12.6 0.0 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain Fungal_trans PF04082.18 KLO09672.1 - 2.1e-16 59.8 0.1 6.5e-16 58.2 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO09672.1 - 1.7e-05 24.8 11.8 3.1e-05 24.0 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RseC_MucC PF04246.12 KLO09673.1 - 0.2 11.6 5.6 2 8.4 3.6 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC FF PF01846.19 KLO09674.1 - 3e-37 126.6 18.1 1.6e-11 44.2 0.1 6.0 6 0 0 6 6 6 5 FF domain WW PF00397.26 KLO09674.1 - 9.3e-10 38.4 12.9 3e-08 33.6 0.1 2.9 3 0 0 3 3 3 2 WW domain RhoGAP-FF1 PF16512.5 KLO09674.1 - 1.6e-08 35.1 1.3 0.016 15.8 0.0 4.2 2 1 1 3 3 3 2 p190-A and -B Rho GAPs FF domain PA26 PF04636.13 KLO09674.1 - 3.2 6.6 9.6 1.7 7.4 3.2 2.3 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Fungal_trans PF04082.18 KLO09675.1 - 5.2e-18 65.0 0.3 1.1e-17 64.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO09675.1 - 0.00018 21.5 15.3 0.00043 20.4 15.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3418 PF11898.8 KLO09675.1 - 0.21 10.2 0.1 0.31 9.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Fungal_trans PF04082.18 KLO09676.1 - 2.4e-17 62.9 0.1 4.6e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO09676.1 - 0.0018 18.3 16.7 0.0032 17.6 16.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Matrilin_ccoil PF10393.9 KLO09676.1 - 0.019 14.8 0.2 0.036 13.9 0.2 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Fer4_6 PF12837.7 KLO09676.1 - 0.22 11.7 2.3 0.6 10.3 2.3 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain F-box-like PF12937.7 KLO09677.1 - 1.8e-06 27.7 0.1 4.5e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09677.1 - 0.062 13.2 0.3 0.21 11.5 0.3 1.9 1 0 0 1 1 1 0 F-box domain Fungal_trans PF04082.18 KLO09678.1 - 9.5e-14 51.1 0.0 1.7e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO09678.1 - 0.00019 21.5 12.6 0.00034 20.7 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Matrilin_ccoil PF10393.9 KLO09678.1 - 0.025 14.4 0.2 0.051 13.4 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin MFS_1 PF07690.16 KLO09679.1 - 7.4e-17 61.3 37.9 7.4e-17 61.3 37.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KLO09680.1 - 3.5e-19 68.9 35.9 5e-19 68.4 35.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_16 PF10294.9 KLO09680.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Spc7_N PF15402.6 KLO09681.1 - 0.033 12.5 4.8 0.038 12.3 4.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Abhydrolase_3 PF07859.13 KLO09682.1 - 4.6e-13 49.5 0.0 1e-12 48.4 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KLO09682.1 - 3.4e-08 32.8 0.0 2.8e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KLO09682.1 - 8.4e-06 24.9 0.0 1.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KLO09682.1 - 0.00014 21.5 0.0 0.00066 19.2 0.0 2.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KLO09682.1 - 0.012 16.2 0.2 0.019 15.6 0.2 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO09682.1 - 0.027 13.7 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF1749 PF08538.10 KLO09682.1 - 0.1 11.7 0.0 0.43 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) DUF2974 PF11187.8 KLO09682.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RPA_C PF08784.11 KLO09683.1 - 4.4e-14 53.0 0.1 8.7e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KLO09683.1 - 1.1e-05 25.3 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KLO09683.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 RNase_PH PF01138.21 KLO09684.1 - 2.4e-18 66.9 0.0 4.3e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KLO09684.1 - 0.049 13.7 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 AhpC-TSA PF00578.21 KLO09685.1 - 5.4e-38 129.7 0.0 8.1e-38 129.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KLO09685.1 - 4.5e-16 58.9 0.0 5.9e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KLO09685.1 - 1.3e-13 50.5 0.0 2.4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KLO09685.1 - 0.1 12.5 0.2 0.43 10.5 0.1 1.9 2 0 0 2 2 2 0 SCO1/SenC DUF1242 PF06842.12 KLO09686.1 - 3.3e-16 58.8 3.4 4.3e-16 58.4 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LST1 PF05083.13 KLO09686.1 - 0.095 13.0 0.2 0.37 11.1 0.2 1.8 2 0 0 2 2 2 0 LST-1 protein Fungal_trans PF04082.18 KLO09687.1 - 3.8e-20 72.0 0.1 7.1e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO09687.1 - 4.2e-05 23.6 11.8 9.7e-05 22.4 11.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KLO09688.1 - 4.9e-11 42.1 0.0 8.5e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO09688.1 - 0.00012 22.2 13.8 0.00019 21.4 13.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KLO09690.1 - 2.7e-18 66.0 0.0 5.8e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO09690.1 - 7.1e-05 22.8 14.7 0.00012 22.1 14.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.13 KLO09691.1 - 3.2e-18 65.9 0.2 4.2e-18 65.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Peroxidase_2 PF01328.17 KLO09693.1 - 1.7e-40 139.5 0.0 2.4e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Gti1_Pac2 PF09729.9 KLO09694.1 - 1.8e-55 187.8 0.0 8.2e-55 185.7 0.0 2.1 3 0 0 3 3 3 1 Gti1/Pac2 family Zn_clus PF00172.18 KLO09695.1 - 0.0028 17.7 1.6 0.0059 16.7 1.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM119 PF15724.5 KLO09695.1 - 0.08 13.0 0.2 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 TMEM119 family F-box-like PF12937.7 KLO09696.1 - 0.0015 18.4 0.4 0.0015 18.4 0.4 1.8 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO09697.1 - 0.00013 21.8 1.9 0.00015 21.6 0.2 2.0 2 0 0 2 2 2 1 F-box-like DUF3759 PF12585.8 KLO09698.1 - 3.4e-11 43.0 9.2 4.7e-11 42.6 8.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3759) DUF1007 PF06226.13 KLO09698.1 - 0.049 13.6 0.6 0.058 13.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) Chromate_transp PF02417.15 KLO09699.1 - 2.2e-56 190.3 35.8 6.4e-29 101.1 12.8 2.5 3 0 0 3 3 3 2 Chromate transporter N2227 PF07942.12 KLO09700.1 - 4.4e-65 219.6 0.0 5.9e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KLO09700.1 - 7.1e-06 26.7 0.1 7.7e-05 23.4 0.0 2.7 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO09700.1 - 0.00031 20.6 0.0 0.00066 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO09700.1 - 0.00045 20.8 0.0 0.086 13.5 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO09700.1 - 0.013 16.1 0.0 1.2 9.9 0.0 3.3 4 0 0 4 4 4 0 Methyltransferase domain Clat_adaptor_s PF01217.20 KLO09701.1 - 1.4e-18 67.2 0.0 2.3e-18 66.5 0.0 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 KLO09701.1 - 0.003 17.6 0.0 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 FCH PF00611.23 KLO09702.1 - 4.1e-16 59.0 1.0 1.1e-15 57.6 0.2 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KLO09702.1 - 1.9e-09 37.0 0.1 3.5e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KLO09702.1 - 6e-07 29.2 0.1 1.2e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KLO09702.1 - 0.00015 21.4 0.0 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_1 PF00036.32 KLO09703.1 - 6.6e-25 84.8 0.2 5e-07 28.8 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KLO09703.1 - 1.5e-20 71.3 1.5 1.2e-06 28.0 0.1 4.3 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KLO09703.1 - 9.4e-20 69.2 0.6 6.2e-07 28.6 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KLO09703.1 - 2.2e-18 66.5 6.1 9.9e-10 38.7 0.3 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KLO09703.1 - 4.1e-15 55.4 0.8 2e-09 37.2 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 KLO09703.1 - 0.0006 20.1 0.0 0.99 9.8 0.0 3.3 3 1 0 3 3 3 1 EF-hand domain GUN4 PF05419.12 KLO09703.1 - 0.025 14.6 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 GUN4-like PHB_acc_N PF07879.11 KLO09703.1 - 0.061 13.4 0.1 0.46 10.6 0.0 2.3 3 0 0 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain EF-hand_2 PF09068.11 KLO09703.1 - 0.064 13.4 0.1 9.4 6.4 0.0 3.3 3 1 0 3 3 3 0 EF hand EF-hand_1 PF00036.32 KLO09705.1 - 1.5e-20 71.2 0.0 6.4e-05 22.2 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KLO09705.1 - 1.8e-18 64.8 0.1 1.1e-05 24.9 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KLO09705.1 - 6e-16 58.6 0.0 2.8e-07 30.9 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KLO09705.1 - 4.7e-15 54.3 0.0 5.1e-05 22.6 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KLO09705.1 - 3.6e-13 49.1 0.6 8.4e-09 35.2 0.1 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KLO09705.1 - 0.029 14.7 0.0 56 4.2 0.0 3.6 3 1 0 3 3 3 0 EF-hand domain Caleosin PF05042.13 KLO09705.1 - 0.055 13.4 0.0 0.74 9.7 0.0 2.5 1 1 1 2 2 2 0 Caleosin related protein IKI3 PF04762.12 KLO09706.1 - 1.5e-248 827.5 0.1 4.4e-191 637.3 0.0 2.1 1 1 1 2 2 2 2 IKI3 family Herpes_UL55 PF04537.12 KLO09706.1 - 0.16 11.9 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein RPN7 PF10602.9 KLO09707.1 - 1.6e-55 187.5 0.3 2.3e-55 187.0 0.3 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KLO09707.1 - 1.3e-14 54.6 0.6 2e-13 50.7 0.1 2.5 2 0 0 2 2 2 1 PCI domain HSCB_C PF07743.13 KLO09707.1 - 0.018 15.5 1.6 0.046 14.2 1.6 1.7 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain PknG_TPR PF16918.5 KLO09707.1 - 0.019 13.7 0.6 0.032 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat DUF3350 PF11830.8 KLO09707.1 - 0.048 14.0 0.3 0.1 12.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) R3H PF01424.22 KLO09708.1 - 3e-12 46.3 0.6 5.5e-12 45.5 0.6 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KLO09708.1 - 4.6e-06 26.6 40.3 2.4e-05 24.3 9.3 13.4 14 1 0 14 14 14 7 NF-X1 type zinc finger Cyclase PF04199.13 KLO09709.1 - 7.1e-30 104.0 0.0 9e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase Polysacc_deac_1 PF01522.21 KLO09709.1 - 0.0015 18.4 0.0 0.5 10.3 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide deacetylase T5orf172 PF10544.9 KLO09710.1 - 0.24 12.0 1.9 0.68 10.5 1.9 1.8 1 0 0 1 1 1 0 T5orf172 domain CENP-Q PF13094.6 KLO09711.1 - 0.0018 18.5 0.0 0.0026 18.0 0.0 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.8 KLO09711.1 - 0.023 14.7 2.1 0.035 14.1 2.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding betaPIX_CC PF16523.5 KLO09711.1 - 0.051 13.4 0.3 0.085 12.7 0.3 1.3 1 0 0 1 1 1 0 betaPIX coiled coil Herpes_UL6 PF01763.16 KLO09711.1 - 0.089 11.3 0.0 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4201 PF13870.6 KLO09711.1 - 0.096 12.4 0.8 0.13 12.0 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Nsp1_C PF05064.13 KLO09711.1 - 0.098 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region PKcGMP_CC PF16808.5 KLO09711.1 - 0.12 12.3 1.7 0.28 11.0 0.0 2.1 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase YabA PF06156.13 KLO09711.1 - 0.15 12.7 0.1 0.21 12.2 0.1 1.2 1 0 0 1 1 1 0 Initiation control protein YabA TolA_bind_tri PF16331.5 KLO09711.1 - 0.35 11.0 2.3 0.48 10.5 2.3 1.2 1 0 0 1 1 1 0 TolA binding protein trimerisation CoA_transf_3 PF02515.17 KLO09712.1 - 4.2e-106 355.2 0.0 4.8e-106 355.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III GST_N_3 PF13417.6 KLO09713.1 - 1.1e-15 57.8 0.1 4.1e-15 56.0 0.1 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO09713.1 - 4.2e-10 39.8 0.0 8.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KLO09713.1 - 0.0061 16.9 0.0 0.44 10.9 0.0 3.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KLO09713.1 - 0.0078 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KLO09713.1 - 0.035 14.1 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UPA PF17217.3 KLO09713.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 UPA domain CBM_1 PF00734.18 KLO09714.1 - 2.6e-13 49.7 9.4 7.4e-13 48.2 9.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF2057 PF09829.9 KLO09714.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Glyco_hydro_31 PF01055.26 KLO09715.1 - 1.2e-142 476.2 3.8 1.8e-142 475.6 3.6 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KLO09715.1 - 1.3e-18 67.0 0.1 5.2e-18 65.1 0.1 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KLO09715.1 - 2.5e-07 30.9 0.0 6.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Cwf_Cwc_15 PF04889.12 KLO09716.1 - 3.9e-85 285.5 27.2 4.5e-85 285.3 27.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KLO09716.1 - 0.013 13.8 33.8 0.016 13.5 33.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KLO09716.1 - 0.17 11.2 34.7 0.23 10.9 34.7 1.1 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 KLO09716.1 - 1.4 8.4 26.0 1.9 8.0 26.0 1.2 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 KLO09716.1 - 2.6 7.3 33.7 3.3 7.0 33.7 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 KLO09716.1 - 2.7 6.0 34.7 3.2 5.7 34.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi LAP1C PF05609.12 KLO09716.1 - 3.9 6.4 14.9 4.7 6.2 14.9 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ALMT PF11744.8 KLO09716.1 - 4.7 5.9 7.4 6.4 5.5 7.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Aminotran_5 PF00266.19 KLO09718.1 - 8.6e-32 110.5 0.0 1.1e-30 106.9 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Uso1_p115_head PF04869.14 KLO09719.1 - 7.5e-45 153.4 0.0 4.6e-38 131.1 0.0 3.5 3 1 0 3 3 3 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KLO09719.1 - 1.2e-11 45.0 20.2 2.3e-11 44.1 20.2 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region HEAT_2 PF13646.6 KLO09719.1 - 0.0002 21.6 0.1 0.0021 18.4 0.0 2.9 1 1 0 1 1 1 1 HEAT repeats Seryl_tRNA_N PF02403.22 KLO09719.1 - 0.00035 20.8 3.8 0.0042 17.3 5.3 2.1 2 0 0 2 2 1 1 Seryl-tRNA synthetase N-terminal domain Rcd1 PF04078.13 KLO09719.1 - 0.003 16.9 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like DUF4407 PF14362.6 KLO09719.1 - 0.0038 16.6 9.6 0.0064 15.9 9.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) HEAT PF02985.22 KLO09719.1 - 0.0081 16.3 3.4 0.87 10.0 0.0 4.8 6 0 0 6 6 4 1 HEAT repeat KASH_CCD PF14662.6 KLO09719.1 - 0.027 14.3 9.1 0.053 13.3 9.1 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH MIF4G_like_2 PF09090.11 KLO09719.1 - 0.041 13.4 3.0 0.078 12.4 3.0 1.4 1 0 0 1 1 1 0 MIF4G like Mo25 PF08569.11 KLO09719.1 - 0.091 12.1 0.1 0.091 12.1 0.1 1.9 2 0 0 2 2 2 0 Mo25-like Cnd1 PF12717.7 KLO09719.1 - 0.13 12.3 0.0 0.5 10.4 0.0 2.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Csm1_N PF18504.1 KLO09719.1 - 0.17 12.2 5.8 1.5 9.2 5.2 2.4 1 1 0 1 1 1 0 Csm1 N-terminal domain FlxA PF14282.6 KLO09719.1 - 0.36 10.8 9.0 0.23 11.5 5.7 2.0 1 1 0 1 1 1 0 FlxA-like protein CSRNP_N PF16019.5 KLO09719.1 - 0.44 10.4 4.9 0.77 9.6 4.9 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Spc7 PF08317.11 KLO09719.1 - 0.48 9.3 7.9 0.99 8.2 7.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 KLO09719.1 - 0.51 10.8 9.3 1.2 9.5 9.3 1.6 1 0 0 1 1 1 0 Fez1 DivIC PF04977.15 KLO09719.1 - 0.62 9.9 8.3 2.1 8.2 2.1 2.8 2 0 0 2 2 2 0 Septum formation initiator DUF2570 PF10828.8 KLO09719.1 - 0.92 9.4 5.2 2.4 8.0 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF3818 PF12825.7 KLO09719.1 - 1.1 8.1 3.5 1.8 7.5 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Mod_r PF07200.13 KLO09719.1 - 1.4 9.0 10.8 0.24 11.5 6.0 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMF_DNA_bd PF12329.8 KLO09719.1 - 1.5 8.8 11.8 10 6.2 4.3 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TAN PF11640.8 KLO09719.1 - 2 8.6 6.0 1.8 8.7 0.2 2.9 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Atx10homo_assoc PF09759.9 KLO09719.1 - 2.4 8.2 5.6 8.5 6.5 0.1 4.0 5 0 0 5 5 4 0 Spinocerebellar ataxia type 10 protein domain Syntaxin-6_N PF09177.11 KLO09719.1 - 2.9 8.5 7.5 2.6 8.7 4.5 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal SlyX PF04102.12 KLO09719.1 - 3.3 8.4 13.2 2.2 8.9 1.1 3.6 1 1 2 3 3 3 0 SlyX F-box-like PF12937.7 KLO09720.1 - 1.7e-09 37.4 3.1 4.6e-08 32.8 0.5 2.5 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KLO09720.1 - 0.062 13.2 5.0 0.091 12.7 0.3 2.5 2 0 0 2 2 2 0 F-box domain Peptidase_S64 PF08192.11 KLO09721.1 - 0.028 12.9 0.0 0.049 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S64 Chordopox_A33R PF05966.12 KLO09724.1 - 0.041 13.1 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein DUF4023 PF13215.6 KLO09724.1 - 0.055 13.5 0.9 0.1 12.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) P2_Phage_GpR PF06891.11 KLO09725.1 - 0.079 13.0 1.2 9.1 6.4 0.3 2.3 2 0 0 2 2 2 0 P2 phage tail completion protein R (GpR) DUF1129 PF06570.11 KLO09725.1 - 0.082 12.4 0.8 0.14 11.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF3959 PF13105.6 KLO09725.1 - 0.23 10.9 1.6 0.41 10.1 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3959) Zn_clus PF00172.18 KLO09726.1 - 2.7e-07 30.6 8.7 5.3e-07 29.7 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TUG-UBL1 PF11470.8 KLO09729.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 TUG ubiquitin-like domain TssN PF17555.2 KLO09729.1 - 0.19 11.1 0.0 0.55 9.6 0.0 1.7 2 0 0 2 2 2 0 Type VI secretion system, TssN GREB1 PF15782.5 KLO09729.1 - 8.2 3.4 12.1 9.9 3.1 12.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lactonase PF10282.9 KLO09730.1 - 1.5e-42 146.1 0.0 1.9e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller GAGE PF05831.11 KLO09731.1 - 0.0052 17.3 0.7 0.008 16.7 0.7 1.3 1 0 0 1 1 1 1 GAGE protein Cwf_Cwc_15 PF04889.12 KLO09731.1 - 8.4 6.0 16.4 11 5.7 16.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Malic_M PF03949.15 KLO09737.1 - 1.1e-78 264.1 0.0 1.7e-78 263.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KLO09737.1 - 1.4e-59 201.0 0.0 2e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Lycopene_cycl PF05834.12 KLO09737.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pex26 PF07163.12 KLO09738.1 - 0.0047 16.3 0.0 0.0098 15.2 0.0 1.5 1 0 0 1 1 1 1 Pex26 protein SPX PF03105.19 KLO09738.1 - 2.8 7.8 5.9 4.1 7.2 5.9 1.3 1 0 0 1 1 1 0 SPX domain p450 PF00067.22 KLO09739.1 - 1.1e-72 245.3 0.0 1.3e-72 245.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box PF00646.33 KLO09740.1 - 0.01 15.7 2.8 0.013 15.4 1.7 1.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO09740.1 - 0.028 14.3 0.7 0.054 13.4 0.7 1.5 1 0 0 1 1 1 0 F-box-like DUF4082 PF13313.6 KLO09740.1 - 0.11 12.5 0.1 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4082) WD40 PF00400.32 KLO09741.1 - 8.5e-15 54.9 5.9 0.012 16.5 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 KLO09741.1 - 0.0086 14.8 0.3 0.48 9.0 0.1 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 DUF3135 PF11333.8 KLO09741.1 - 0.064 13.5 0.2 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) DUF884 PF05959.11 KLO09741.1 - 0.21 11.2 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) eIF3_subunit PF08597.10 KLO09742.1 - 6.4e-61 206.4 26.8 7.1e-61 206.2 26.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF2935 PF11155.8 KLO09742.1 - 0.0047 17.3 0.1 0.0084 16.4 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF2935) PBP1_TM PF14812.6 KLO09742.1 - 2.1 8.8 15.9 0.075 13.4 4.7 3.4 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4678 PF15727.5 KLO09742.1 - 6.2 6.0 16.9 0.96 8.6 10.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4678) COQ9 PF08511.11 KLO09743.1 - 2.9e-08 33.4 0.0 4.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 COQ9 p450 PF00067.22 KLO09744.1 - 6.1e-67 226.4 0.0 7.4e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO09746.1 - 8.8e-64 215.9 0.0 1.2e-63 215.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_53 PF07745.13 KLO09747.1 - 6.2e-84 281.9 0.0 7.6e-84 281.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.18 KLO09747.1 - 0.044 13.2 0.0 0.079 12.4 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) p450 PF00067.22 KLO09748.1 - 9.4e-63 212.6 0.0 1.1e-62 212.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_C PF05199.13 KLO09749.1 - 4.1e-11 43.6 0.3 1e-10 42.3 0.1 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KLO09749.1 - 0.03 13.7 0.0 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase SGTA_dimer PF16546.5 KLO09749.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Homodimerisation domain of SGTA PDGLE PF13190.6 KLO09749.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 PDGLE domain p450 PF00067.22 KLO09750.1 - 1.6e-65 221.6 0.0 2e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cys_rich_VLP PF14194.6 KLO09751.1 - 0.11 12.7 0.3 0.17 12.0 0.3 1.4 1 0 0 1 1 1 0 Cysteine-rich VLP RhoGAP PF00620.27 KLO09752.1 - 1.1e-36 125.9 0.0 1.8e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain p450 PF00067.22 KLO09753.1 - 3.2e-70 237.2 0.0 3.9e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_17 PF00332.18 KLO09754.1 - 5.2e-12 46.0 0.9 5.2e-12 46.0 0.9 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 ETRAMP PF09716.10 KLO09754.1 - 0.014 15.4 0.3 0.029 14.4 0.3 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2116 PF09889.9 KLO09754.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Abhydrolase_2 PF02230.16 KLO09755.1 - 5.2e-11 42.8 0.0 1.4e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KLO09755.1 - 5.5e-05 23.9 1.9 7.3e-05 23.5 1.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Amino_oxidase PF01593.24 KLO09755.1 - 0.053 12.8 0.1 0.082 12.2 0.1 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase F-box-like PF12937.7 KLO09757.1 - 0.012 15.5 0.2 0.012 15.5 0.2 1.9 2 0 0 2 2 2 0 F-box-like LRR_6 PF13516.6 KLO09757.1 - 0.014 15.4 0.4 23 5.4 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.7 KLO09757.1 - 0.03 14.7 3.8 0.9 10.1 0.1 4.2 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KLO09757.1 - 0.21 11.4 2.9 26 4.7 0.0 3.7 4 0 0 4 4 4 0 Leucine rich repeat Erg28 PF03694.13 KLO09758.1 - 6.5e-41 139.2 8.1 7.6e-41 138.9 8.1 1.1 1 0 0 1 1 1 1 Erg28 like protein GIIM PF08388.11 KLO09758.1 - 0.09 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Group II intron, maturase-specific domain Dynamin_M PF01031.20 KLO09760.1 - 1.1e-26 93.8 0.3 8.3e-26 90.8 0.3 2.1 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KLO09760.1 - 6e-20 72.0 0.0 2e-19 70.3 0.0 1.9 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 KLO09760.1 - 3.8e-07 30.2 0.0 1.1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KLO09760.1 - 5.5e-05 23.2 0.0 0.00062 19.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KLO09760.1 - 0.017 15.5 0.3 1.1 9.7 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 KLO09760.1 - 0.065 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_M PF01031.20 KLO09761.1 - 3.9e-29 101.8 0.0 1.4e-28 99.9 0.0 1.8 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KLO09761.1 - 2e-27 96.3 0.0 8.5e-27 94.2 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KLO09761.1 - 1e-06 28.8 0.5 3.8e-05 23.8 0.0 2.8 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KLO09761.1 - 7e-06 26.1 0.1 5.9e-05 23.1 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KLO09761.1 - 0.0092 16.4 0.1 0.094 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KLO09761.1 - 0.026 14.3 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KLO09761.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter p450 PF00067.22 KLO09762.1 - 2.1e-59 201.5 0.0 3e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Cu2_monooxygen PF01082.20 KLO09762.1 - 0.038 14.2 0.1 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Fra10Ac1 PF09725.9 KLO09763.1 - 1.5e-46 157.5 0.6 2.1e-46 157.0 0.6 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Glyco_hydro_11 PF00457.17 KLO09763.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 Presenilin PF01080.17 KLO09763.1 - 4.1 6.1 8.0 5.1 5.8 8.0 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KLO09763.1 - 5.9 5.1 17.3 7 4.8 17.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 KLO09763.1 - 6.1 5.5 8.0 8.3 5.1 8.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Methyltransf_28 PF02636.17 KLO09764.1 - 4.3e-58 197.0 0.0 5.4e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase eIF-6 PF01912.18 KLO09765.1 - 3e-82 274.8 0.1 4.1e-82 274.4 0.1 1.2 1 0 0 1 1 1 1 eIF-6 family PAS_8 PF13188.7 KLO09765.1 - 0.093 12.8 0.0 0.73 9.9 0.1 2.2 2 0 0 2 2 2 0 PAS domain AhpC-TSA_2 PF13911.6 KLO09766.1 - 2e-16 60.1 0.0 3.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KLO09766.1 - 0.00052 19.9 0.0 0.00069 19.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Aa_trans PF01490.18 KLO09767.1 - 3.6e-84 282.8 27.9 4.3e-84 282.6 27.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YpmT PF17431.2 KLO09767.1 - 2.1 8.4 6.3 0.33 11.0 0.8 2.6 3 0 0 3 3 3 0 Uncharacterized YmpT-like Methyltransf_2 PF00891.18 KLO09769.1 - 1.5e-19 70.2 0.3 2.2e-18 66.3 0.1 2.4 2 1 0 2 2 2 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KLO09769.1 - 0.0067 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO09769.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DprA_WH PF17782.1 KLO09769.1 - 0.086 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 DprA winged helix domain F-box-like PF12937.7 KLO09770.1 - 1.2e-05 25.1 2.4 1.4e-05 24.9 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO09770.1 - 1.7e-05 24.5 0.2 5.4e-05 23.0 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO09772.1 - 0.0058 16.5 0.0 0.02 14.8 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09772.1 - 0.0073 16.2 0.0 0.027 14.3 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO09773.1 - 1.7e-06 27.8 8.1 5.3e-06 26.2 5.7 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO09773.1 - 1.1 9.2 4.1 3.2 7.7 1.5 2.7 2 0 0 2 2 2 0 F-box domain PTPlike_phytase PF14566.6 KLO09774.1 - 1.9e-07 31.3 0.0 2.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 KLO09774.1 - 2.1e-05 24.4 0.0 2.8e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KLO09774.1 - 0.0044 16.6 0.0 0.0055 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KLO09774.1 - 0.014 15.4 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 KLO09774.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) APH PF01636.23 KLO09775.1 - 3e-10 40.5 0.0 1.8e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KLO09775.1 - 0.044 12.6 0.0 0.099 11.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) F-box-like PF12937.7 KLO09776.1 - 3.6e-05 23.6 5.9 0.00017 21.4 5.9 2.2 1 1 0 1 1 1 1 F-box-like APH PF01636.23 KLO09777.1 - 3.7e-14 53.3 0.1 7.1e-14 52.3 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.23 KLO09778.1 - 1.1e-11 45.2 0.6 7.5e-10 39.1 0.1 3.1 2 2 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KLO09778.1 - 0.16 10.8 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) 4HBT PF03061.22 KLO09779.1 - 9.9e-11 41.9 0.0 1.5e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KLO09779.1 - 0.0016 18.7 0.1 0.0059 16.9 0.1 1.8 1 1 0 1 1 1 1 Thioesterase-like superfamily F-box-like PF12937.7 KLO09780.1 - 0.0057 16.5 5.6 0.028 14.3 5.6 2.2 1 1 0 1 1 1 1 F-box-like Asn_synthase PF00733.21 KLO09780.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase DUF3176 PF11374.8 KLO09783.1 - 0.073 13.3 1.8 0.18 12.0 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) F-box-like PF12937.7 KLO09785.1 - 1e-06 28.5 1.2 4.4e-06 26.5 1.2 2.1 1 1 0 1 1 1 1 F-box-like Pkinase PF00069.25 KLO09787.1 - 1.2e-36 126.4 0.0 2.5e-36 125.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO09787.1 - 2.9e-34 118.5 0.0 3.7e-33 114.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase VASt PF16016.5 KLO09787.1 - 2.2e-11 44.4 0.4 2.2e-11 44.4 0.4 1.7 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain Kdo PF06293.14 KLO09787.1 - 0.024 14.0 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KLO09787.1 - 0.033 13.5 0.1 0.67 9.2 0.1 2.2 1 1 0 1 1 1 0 Kinase-like PPP4R2 PF09184.11 KLO09788.1 - 0.88 9.1 8.5 1.1 8.8 8.5 1.2 1 0 0 1 1 1 0 PPP4R2 RXT2_N PF08595.11 KLO09788.1 - 1 9.3 5.2 1.8 8.6 5.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP_sp32 PF07222.12 KLO09788.1 - 1.2 8.6 6.7 2 7.8 6.7 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Nop14 PF04147.12 KLO09788.1 - 1.3 7.1 10.0 1.7 6.8 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KLO09788.1 - 2.1 6.5 6.0 2.5 6.3 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KLO09788.1 - 7 5.9 10.7 10 5.3 10.7 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KLO09788.1 - 7.1 4.6 13.5 9.6 4.2 13.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase_Tyr PF07714.17 KLO09789.1 - 9.1e-42 143.1 0.0 1.5e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO09789.1 - 6.1e-41 140.5 0.0 1e-40 139.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO09789.1 - 1.4e-06 27.9 0.0 2.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO09789.1 - 0.1 12.2 0.1 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.17 KLO09790.1 - 8.7e-45 153.0 0.0 1.1e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO09790.1 - 2e-36 125.7 0.0 2.6e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO09790.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO09790.1 - 0.014 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM178 PF14816.6 KLO09790.1 - 0.034 13.1 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 Pkinase PF00069.25 KLO09791.1 - 7.8e-39 133.6 0.0 1.1e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO09791.1 - 9.7e-39 133.2 0.0 1.3e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO09791.1 - 0.016 14.5 0.0 0.043 13.1 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KLO09792.1 - 1.1e-43 149.5 0.0 1.6e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO09792.1 - 1.1e-41 142.8 0.0 1.6e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO09792.1 - 4.1e-05 23.1 0.0 6.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO09792.1 - 0.003 17.5 0.0 0.014 15.3 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO09792.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KLO09794.1 - 3.4e-40 138.1 0.0 4.8e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO09794.1 - 4.4e-39 134.3 0.0 6.4e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO09794.1 - 0.00028 20.3 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO09794.1 - 0.05 13.2 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KLO09794.1 - 0.073 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DPBB_1 PF03330.18 KLO09795.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Lytic transglycolase DDE_3 PF13358.6 KLO09796.1 - 0.002 17.9 0.0 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KLO09796.1 - 0.29 11.2 2.3 0.41 10.7 0.4 2.2 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain DUF5127 PF17168.4 KLO09797.1 - 5.9e-50 170.2 1.3 1.6e-49 168.8 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO09797.1 - 5.4e-49 166.2 1.1 1.2e-48 165.1 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO09797.1 - 1.1e-35 123.5 0.2 2.1e-35 122.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid6H PF17389.2 KLO09797.1 - 0.0071 15.6 0.0 0.028 13.7 0.0 1.8 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF4964 PF16334.5 KLO09797.1 - 0.015 14.8 1.2 0.19 11.3 1.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4964) Peptidase_M76 PF09768.9 KLO09798.1 - 2.5e-30 105.5 1.1 1.6e-22 80.1 0.1 2.1 2 0 0 2 2 2 2 Peptidase M76 family Peptidase_C14 PF00656.22 KLO09800.1 - 4.1e-19 69.5 0.0 8.4e-19 68.5 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Peptidase_M76 PF09768.9 KLO09801.1 - 9e-44 149.3 4.9 1e-43 149.1 4.9 1.0 1 0 0 1 1 1 1 Peptidase M76 family Dicty_spore_N PF04562.12 KLO09801.1 - 0.048 14.4 2.1 3.9 8.2 0.2 2.0 1 1 0 2 2 2 0 Dictyostelium spore coat protein, N terminus AAA PF00004.29 KLO09831.1 - 1.9e-41 141.6 0.0 3.8e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KLO09831.1 - 3e-06 26.9 0.1 7.3e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KLO09831.1 - 9e-06 25.7 0.0 2.9e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KLO09831.1 - 0.00011 22.4 0.0 0.0052 17.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO09831.1 - 0.00021 21.7 0.0 0.0025 18.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KLO09831.1 - 0.00027 21.1 0.0 0.00069 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KLO09831.1 - 0.00036 19.8 0.0 0.00061 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KLO09831.1 - 0.0035 17.1 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KLO09831.1 - 0.0076 15.8 0.0 0.021 14.4 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 KLO09831.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KLO09831.1 - 0.023 14.4 0.1 0.14 11.9 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KLO09831.1 - 0.024 14.8 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KLO09831.1 - 0.032 14.1 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KLO09831.1 - 0.042 13.0 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KLO09831.1 - 0.042 14.2 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KLO09831.1 - 0.056 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KLO09831.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KLO09831.1 - 0.08 12.9 0.1 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 NTPase Sigma54_activ_2 PF14532.6 KLO09831.1 - 0.084 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 KLO09831.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KLO09831.1 - 0.098 12.6 0.0 6.5 6.6 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KLO09831.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RRM_1 PF00076.22 KLO09832.1 - 0.04 13.7 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GST_N_2 PF13409.6 KLO09833.1 - 2.6e-21 75.7 0.1 1.2e-20 73.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO09833.1 - 6.4e-16 58.1 0.1 1.3e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KLO09833.1 - 7.6e-09 35.7 0.1 1.3e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO09833.1 - 1.6e-06 28.2 0.1 2.9e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KLO09833.1 - 0.0018 18.6 0.0 0.029 14.8 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KLO09833.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ubiquitin PF00240.23 KLO09834.1 - 1.3e-15 56.9 0.0 1.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KLO09834.1 - 2.3e-06 27.3 0.0 3.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Blt1 PF12754.7 KLO09834.1 - 9.7e-06 26.0 0.6 1.9e-05 25.1 0.6 1.4 1 0 0 1 1 1 1 Blt1 N-terminal domain Ndufs5 PF10200.9 KLO09835.1 - 3.6e-05 23.9 0.4 4.6e-05 23.6 0.4 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 KLO09835.1 - 0.00021 21.3 3.2 0.00032 20.7 3.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KLO09835.1 - 0.0035 17.4 2.4 0.014 15.5 2.8 1.8 1 1 1 2 2 2 2 CHCH domain UPF0203 PF05254.12 KLO09835.1 - 0.054 13.7 2.9 0.078 13.2 2.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF3128 PF11326.8 KLO09835.1 - 0.07 13.5 5.8 0.34 11.3 5.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Defensin_5 PF18251.1 KLO09835.1 - 0.085 13.0 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Fungal defensin Copsin PADR1 PF08063.12 KLO09835.1 - 0.65 9.8 4.6 2.2 8.1 0.5 2.5 2 1 1 3 3 3 0 PADR1 (NUC008) domain TFIIE_alpha PF02002.17 KLO09836.1 - 1.5e-18 66.6 0.4 3.3e-18 65.5 0.4 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 KLO09836.1 - 8.1e-05 22.8 1.3 0.00011 22.4 0.0 1.9 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 KLO09836.1 - 0.0052 16.3 2.2 0.0079 15.7 1.3 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding RecO_N_2 PF13114.6 KLO09836.1 - 0.039 13.7 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 RecO N terminal zf-TFIIB PF13453.6 KLO09836.1 - 0.091 12.1 0.5 0.24 10.8 0.5 1.8 1 0 0 1 1 1 0 Transcription factor zinc-finger DUF89 PF01937.19 KLO09838.1 - 2e-96 323.0 0.6 2.3e-96 322.8 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 GST_N_2 PF13409.6 KLO09840.1 - 6.6e-21 74.4 0.0 1.4e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO09840.1 - 4.5e-16 58.6 0.0 8.8e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KLO09840.1 - 9.8e-10 38.5 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO09840.1 - 4.1e-06 26.9 0.0 8.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KLO09840.1 - 0.00022 21.6 0.0 0.0078 16.6 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tab2_like PF06485.11 KLO09840.1 - 0.032 13.7 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 Phyto_Pns9_10 PF05878.11 KLO09840.1 - 0.066 12.3 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 GST_C_6 PF17171.4 KLO09840.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain QIL1 PF15884.5 KLO09840.1 - 0.12 12.9 0.0 0.39 11.3 0.0 1.8 1 0 0 1 1 1 0 MICOS complex subunit MIC13, QIL1 LRR_6 PF13516.6 KLO09841.1 - 1.1e-05 25.0 13.5 0.052 13.6 0.2 5.9 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 KLO09841.1 - 0.00019 21.7 8.5 0.76 10.3 0.1 4.5 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) SLM4 PF16818.5 KLO09841.1 - 0.079 12.9 0.4 0.15 12.0 0.4 1.5 1 1 0 1 1 1 0 Protein SLM4 DUF1232 PF06803.12 KLO09842.1 - 2.8 7.8 4.7 0.76 9.6 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1232) OPT PF03169.15 KLO09843.1 - 1.9e-177 591.6 65.7 2.2e-177 591.4 65.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RES PF08808.11 KLO09843.1 - 0.031 14.1 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 RES domain DUF1770 PF08589.10 KLO09844.1 - 4.2e-07 30.8 0.5 1.4e-06 29.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1770) PIG-L PF02585.17 KLO09846.1 - 2.8e-22 79.8 0.0 3.7e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase UvrD_C_2 PF13538.6 KLO09846.1 - 0.095 12.5 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain APG12 PF04110.13 KLO09847.1 - 4.9e-30 103.8 0.0 6e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KLO09847.1 - 0.0041 17.3 0.0 0.0048 17.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Rotamase_3 PF13616.6 KLO09849.1 - 1.3e-18 67.6 0.1 2e-18 67.0 0.1 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KLO09849.1 - 5.7e-16 59.3 0.0 7.5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KLO09849.1 - 2.5e-05 25.1 0.0 2.9e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain ABC_tran PF00005.27 KLO09850.1 - 2.2e-24 86.5 0.2 1.2e-14 55.0 0.1 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KLO09850.1 - 4.6e-10 39.3 1.5 0.0064 15.9 0.0 3.2 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KLO09850.1 - 3.4e-09 36.9 0.1 0.00059 19.7 0.0 3.3 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KLO09850.1 - 0.00049 20.4 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KLO09850.1 - 0.0043 17.0 0.0 0.0092 15.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Lactococcin PF04369.13 KLO09850.1 - 0.011 15.8 0.0 4.1 7.6 0.0 2.9 3 0 0 3 3 3 0 Lactococcin-like family AAA_7 PF12775.7 KLO09850.1 - 0.016 14.7 0.0 0.05 13.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_13 PF13166.6 KLO09850.1 - 0.031 12.9 0.2 0.29 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 KLO09850.1 - 0.031 13.1 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SbcCD_C PF13558.6 KLO09850.1 - 0.034 14.4 0.0 15 5.9 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.9 KLO09850.1 - 0.043 13.6 0.1 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 KLO09850.1 - 0.062 13.8 1.1 0.15 12.6 1.1 1.6 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KLO09850.1 - 0.098 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KLO09850.1 - 0.13 12.6 0.1 0.24 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain PIG-S PF10510.9 KLO09851.1 - 8.3e-115 384.5 4.4 1.7e-113 380.2 4.4 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Rep_fac-A_3 PF08661.11 KLO09852.1 - 2.8e-20 72.6 0.0 2.9e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Glyco_hydro_1 PF00232.18 KLO09853.1 - 4.7e-107 358.2 0.5 5.6e-107 358.0 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 UQ_con PF00179.26 KLO09854.1 - 5.2e-55 185.0 0.0 5.8e-55 184.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KLO09854.1 - 0.0068 16.7 0.0 0.009 16.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KLO09854.1 - 0.0079 15.9 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KLO09854.1 - 0.08 12.8 0.3 0.15 12.0 0.3 1.4 1 1 0 1 1 1 0 UEV domain PIG-L PF02585.17 KLO09855.1 - 2.2e-14 54.2 0.0 3.2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase PAC2 PF09754.9 KLO09855.1 - 0.041 13.9 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 PAC2 family AbLIM_anchor PF16182.5 KLO09855.1 - 0.29 10.9 0.6 0.42 10.4 0.6 1.1 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM Myb_DNA-binding PF00249.31 KLO09856.1 - 5.3e-15 55.3 0.0 6.3e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KLO09856.1 - 6.8e-11 42.3 0.1 0.00014 22.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KLO09856.1 - 3.3e-06 26.9 4.0 0.0081 16.0 0.0 2.8 3 0 0 3 3 3 2 Myb DNA-binding like NUDE_C PF04880.13 KLO09856.1 - 0.19 12.2 0.1 0.19 12.2 0.1 3.2 3 0 0 3 3 3 0 NUDE protein, C-terminal conserved region Glyco_transf_20 PF00982.21 KLO09858.1 - 7.1e-135 450.3 0.0 2.3e-134 448.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KLO09858.1 - 1.2e-68 230.7 0.0 2.2e-68 229.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase MFS_5 PF05631.14 KLO09859.1 - 2.1e-73 247.3 5.6 3.8e-73 246.4 5.6 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KLO09859.1 - 4.1e-19 68.7 23.2 4.1e-19 68.7 23.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MASE4 PF17158.4 KLO09859.1 - 5.3 6.2 12.1 0.03 13.6 1.3 2.6 3 1 0 3 3 3 0 Membrane-associated sensor, integral membrane domain RRM_1 PF00076.22 KLO09860.1 - 6.2e-48 160.5 0.0 2.4e-16 59.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KLO09860.1 - 0.00036 20.5 0.0 4.1 7.5 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 KLO09860.1 - 0.00091 19.3 0.0 0.055 13.5 0.0 2.8 3 0 0 3 3 3 1 Limkain b1 DUF3343 PF11823.8 KLO09860.1 - 0.012 15.1 0.0 0.044 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Cys_Met_Meta_PP PF01053.20 KLO09862.1 - 2.3e-30 105.4 0.0 3.1e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KLO09862.1 - 0.00012 21.4 0.0 0.00035 19.9 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II MFS_1 PF07690.16 KLO09863.1 - 2.2e-12 46.6 63.3 2.1e-11 43.3 35.7 2.8 2 1 0 3 3 3 2 Major Facilitator Superfamily DUF4094 PF13334.6 KLO09863.1 - 0.097 13.1 0.2 0.39 11.1 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Aldo_ket_red PF00248.21 KLO09864.1 - 8e-37 127.0 0.1 1.1e-36 126.6 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF469 PF04320.14 KLO09864.1 - 0.12 13.2 0.1 0.55 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein with unknown function (DUF469) Prok-JAB PF14464.6 KLO09869.1 - 0.091 12.5 1.1 0.098 12.4 1.1 1.1 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain PBD PF00786.28 KLO09870.1 - 0.0004 20.7 0.0 0.00071 19.9 0.0 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain BolA PF01722.18 KLO09875.1 - 3e-13 49.9 0.0 3.1e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein CitMHS PF03600.16 KLO09876.1 - 8.7e-14 51.4 11.5 8.7e-14 51.4 11.5 1.7 2 0 0 2 2 2 1 Citrate transporter ArsB PF02040.15 KLO09876.1 - 3.1e-11 43.2 10.2 2.1e-10 40.5 1.8 2.4 2 0 0 2 2 2 2 Arsenical pump membrane protein Gate PF07670.14 KLO09876.1 - 0.0022 18.2 1.8 0.0022 18.2 1.8 2.7 3 1 0 3 3 3 1 Nucleoside recognition PIG-P PF08510.12 KLO09876.1 - 2.7 7.9 0.0 2.7 7.9 0.0 3.5 4 0 0 4 4 4 0 PIG-P COX4_pro_2 PF07835.12 KLO09877.1 - 0.42 10.8 4.7 2.8 8.1 0.0 2.7 2 1 1 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV Maf1 PF09174.10 KLO09878.1 - 2e-39 135.5 0.0 1.5e-32 113.2 0.0 2.3 2 0 0 2 2 2 2 Maf1 regulator LRR_4 PF12799.7 KLO09879.1 - 1.2e-35 120.9 22.3 5.7e-08 32.9 0.2 6.7 5 1 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KLO09879.1 - 3.5e-26 90.7 24.8 8.3e-12 44.7 1.1 6.3 4 1 4 8 8 8 6 Leucine rich repeat LRR_9 PF14580.6 KLO09879.1 - 3.7e-19 68.9 6.8 2.1e-08 33.9 2.5 3.5 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KLO09879.1 - 1.1e-06 28.4 23.2 1.9 9.3 0.1 9.5 9 2 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 KLO09879.1 - 0.0028 17.6 14.3 27 5.2 0.0 8.0 8 0 0 8 8 8 0 Leucine Rich repeat FTH PF01827.27 KLO09879.1 - 0.0078 16.0 0.6 0.2 11.4 0.1 2.7 1 1 1 2 2 2 1 FTH domain LRR_5 PF13306.6 KLO09879.1 - 0.083 12.8 0.0 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) UB2H PF14814.6 KLO09879.1 - 0.3 11.1 1.3 59 3.8 0.0 4.1 2 2 2 4 4 4 0 Bifunctional transglycosylase second domain LysM PF01476.20 KLO09880.1 - 0.027 14.5 0.1 0.089 12.9 0.0 1.9 2 0 0 2 2 2 0 LysM domain UCR_6-4kD PF08997.10 KLO09881.1 - 0.21 11.6 2.1 13 5.8 0.4 2.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Peptidase_C14 PF00656.22 KLO09887.1 - 2e-35 122.9 0.0 7.6e-35 121.0 0.0 1.8 1 1 0 1 1 1 1 Caspase domain p450 PF00067.22 KLO09888.1 - 2.4e-68 231.0 0.0 2.8e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO09889.1 - 1.4e-68 231.8 0.0 1.6e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO09890.1 - 1.4e-52 179.0 0.0 1.5e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MOEP19 PF16005.5 KLO09890.1 - 0.022 14.7 0.2 0.76 9.8 0.0 2.4 2 0 0 2 2 2 0 KH-like RNA-binding domain p450 PF00067.22 KLO09891.1 - 1.9e-61 208.2 0.0 1e-35 123.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KLO09892.1 - 1.4e-67 228.4 0.0 1.7e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MINDY_DUB PF04424.13 KLO09893.1 - 1e-26 93.2 0.0 2.9e-26 91.8 0.0 1.7 2 0 0 2 2 2 1 MINDY deubiquitinase PFK PF00365.20 KLO09894.1 - 4.5e-188 623.4 0.0 3.6e-103 344.8 0.0 3.1 2 1 0 2 2 2 2 Phosphofructokinase UVR PF02151.19 KLO09894.1 - 0.092 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif WLM PF08325.10 KLO09895.1 - 9.2e-32 110.7 2.6 1.2e-30 107.1 2.6 2.3 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 KLO09895.1 - 2e-05 24.7 0.3 2e-05 24.7 0.3 2.4 3 0 0 3 3 3 1 Protein of unknown function DUF45 zf-RanBP PF00641.18 KLO09895.1 - 0.00023 20.4 4.9 0.0004 19.6 4.9 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Caenor_Her-1 PF09232.10 KLO09895.1 - 0.041 14.0 0.7 0.087 13.0 0.7 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans Her-1 SprT-like PF10263.9 KLO09895.1 - 0.082 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 SprT-like family PAXIP1_C PF15364.6 KLO09896.1 - 0.013 15.8 2.6 0.016 15.5 2.6 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Astro_capsid_p PF12226.8 KLO09896.1 - 0.14 11.3 14.2 0.16 11.1 14.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4763 PF15960.5 KLO09896.1 - 0.26 10.6 0.8 0.28 10.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Hamartin PF04388.12 KLO09897.1 - 6.6 5.3 14.4 8.2 5.0 14.4 1.1 1 0 0 1 1 1 0 Hamartin protein p450 PF00067.22 KLO09898.1 - 1.1e-11 44.2 0.0 1.4e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KLO09900.1 - 4e-08 33.0 1.6 3.3e-06 26.9 0.3 2.7 3 0 0 3 3 3 2 F-box-like Nucleoside_tran PF01733.18 KLO09901.1 - 5.5e-32 111.4 18.0 1.3e-18 67.5 14.8 3.4 2 1 0 2 2 2 2 Nucleoside transporter DUF2417 PF10329.9 KLO09901.1 - 0.026 13.9 0.3 0.07 12.5 0.3 1.7 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Abhydrolase_3 PF07859.13 KLO09902.1 - 4.8e-15 56.0 0.0 2.4e-14 53.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KLO09902.1 - 2.1e-06 26.9 0.1 1.6e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KLO09902.1 - 0.00031 19.7 0.0 0.00041 19.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KLO09902.1 - 0.0084 15.4 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FAD_binding_3 PF01494.19 KLO09903.1 - 6.3e-66 223.0 0.0 7.9e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KLO09903.1 - 0.012 15.9 0.1 0.028 14.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KLO09903.1 - 0.015 15.7 0.0 0.057 13.9 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.24 KLO09903.1 - 0.018 14.6 0.4 0.041 13.5 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KLO09903.1 - 0.033 13.1 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.16 KLO09903.1 - 0.036 13.7 0.2 0.071 12.7 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KLO09903.1 - 0.041 13.1 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KLO09904.1 - 1.5e-31 109.6 44.0 3.5e-25 88.7 17.5 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 KLO09904.1 - 2.4e-05 23.0 27.3 0.00033 19.2 27.2 2.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KLO09904.1 - 4.9e-05 22.4 9.4 4.9e-05 22.4 9.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Iron_permease PF04120.12 KLO09904.1 - 0.0093 15.7 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Low affinity iron permease CRAL_TRIO PF00650.20 KLO09905.1 - 9.6e-36 122.9 0.0 1.5e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KLO09905.1 - 3.3e-11 43.2 1.7 7.3e-11 42.1 1.7 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KLO09905.1 - 0.036 14.2 0.0 0.066 13.4 0.0 1.6 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain PSA_CBD PF18341.1 KLO09905.1 - 0.92 9.6 6.4 0.97 9.5 0.1 3.3 4 0 0 4 4 4 0 PSA endolysin C-terminal cell wall binding domain Tweety PF04906.13 KLO09907.1 - 0.047 12.4 1.8 0.051 12.2 1.8 1.1 1 0 0 1 1 1 0 Tweety Actin PF00022.19 KLO09910.1 - 4.2e-150 499.9 0.0 1.8e-149 497.8 0.0 1.7 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 KLO09910.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase VWA_2 PF13519.6 KLO09911.1 - 1.7e-21 76.9 0.0 5.3e-21 75.3 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KLO09911.1 - 1.3e-07 31.6 0.0 2.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KLO09911.1 - 1.2e-06 28.0 36.7 0.00087 19.1 3.8 4.1 4 0 0 4 4 4 3 Ubiquitin interaction motif VWA PF00092.28 KLO09911.1 - 4e-06 27.2 0.0 7.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain IML1 PF12257.8 KLO09911.1 - 0.039 13.1 0.1 0.059 12.5 0.1 1.2 1 0 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 EMG1 PF03587.14 KLO09912.1 - 1.3e-75 253.3 0.0 1.6e-75 253.1 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase SCO1-SenC PF02630.14 KLO09913.1 - 2.4e-46 157.0 0.0 3.4e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KLO09913.1 - 1.7e-08 34.4 0.0 8.3e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KLO09913.1 - 0.0023 18.2 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like NDUF_B7 PF05676.13 KLO09914.1 - 3.9e-30 103.4 2.4 4.6e-30 103.1 2.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) zf-MYND PF01753.18 KLO09917.1 - 4.2e-10 39.5 13.2 7.3e-10 38.8 13.2 1.4 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 KLO09917.1 - 0.45 8.3 1.0 0.62 7.9 1.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 FGGY_C PF02782.16 KLO09918.1 - 3.1e-46 157.6 0.0 4.3e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KLO09918.1 - 1e-17 64.5 0.0 1e-15 58.0 0.0 2.7 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KLO09918.1 - 0.054 13.0 0.1 0.28 10.6 0.1 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Euplotes_phero PF05842.11 KLO09918.1 - 0.08 13.5 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Hexokinase_1 PF00349.21 KLO09918.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Hexokinase JmjC PF02373.22 KLO09920.1 - 4.2e-15 56.2 0.0 1.3e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase FYVE PF01363.21 KLO09920.1 - 0.0037 17.4 1.9 0.0037 17.4 1.9 2.3 3 0 0 3 3 3 1 FYVE zinc finger Cupin_8 PF13621.6 KLO09920.1 - 0.044 13.5 0.0 0.25 11.0 0.0 2.2 1 1 0 1 1 1 0 Cupin-like domain Cupin_4 PF08007.12 KLO09920.1 - 0.11 11.9 0.0 0.45 9.9 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein zf-C5HC2 PF02928.16 KLO09920.1 - 0.12 12.8 2.8 0.34 11.3 2.8 1.8 1 0 0 1 1 1 0 C5HC2 zinc finger C1_1 PF00130.22 KLO09920.1 - 0.19 11.6 4.1 0.54 10.2 4.1 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Response_reg PF00072.24 KLO09921.1 - 1.8e-22 79.6 0.0 1.7e-15 57.2 0.0 2.8 2 0 0 2 2 2 2 Response regulator receiver domain UAA PF08449.11 KLO09922.1 - 4.8e-79 265.7 3.8 7.4e-79 265.1 3.8 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KLO09922.1 - 0.0032 17.6 22.4 0.026 14.7 9.1 3.6 3 1 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 KLO09922.1 - 0.0094 15.2 2.5 0.0094 15.2 2.5 2.2 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport DUF2569 PF10754.9 KLO09922.1 - 0.019 15.4 5.3 0.25 11.8 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Phage_holin_5_2 PF16079.5 KLO09922.1 - 0.58 10.5 4.2 0.29 11.5 0.3 2.5 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V DUF3969 PF13108.6 KLO09923.1 - 0.0069 16.4 0.3 0.019 15.0 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3969) DUF2524 PF10732.9 KLO09923.1 - 0.039 14.3 0.3 0.12 12.7 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) MIF4G_like_2 PF09090.11 KLO09925.1 - 1.2e-71 241.3 0.8 2.2e-71 240.5 0.8 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 KLO09925.1 - 1.1e-65 221.0 0.0 2.5e-65 219.8 0.0 1.6 1 0 0 1 1 1 1 MIF4G like DUF325 PF03804.13 KLO09925.1 - 0.03 14.4 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 Viral proteins of unknown function PPR_2 PF13041.6 KLO09926.1 - 2.9e-08 33.8 0.1 0.0019 18.4 0.0 5.6 7 0 0 7 7 7 2 PPR repeat family PPR PF01535.20 KLO09926.1 - 1.4e-06 28.2 0.3 0.29 11.5 0.0 6.1 7 0 0 7 7 7 1 PPR repeat PPR_1 PF12854.7 KLO09926.1 - 0.0015 18.1 0.0 6.4 6.6 0.0 4.5 4 0 0 4 4 4 1 PPR repeat IF3_C PF00707.22 KLO09927.1 - 6.1e-09 35.7 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KLO09927.1 - 2.2e-06 27.5 0.2 0.0077 15.9 0.1 2.2 1 1 1 2 2 2 2 Mitochondrial translation initiation factor IF3_N PF05198.16 KLO09927.1 - 0.028 14.7 0.1 0.061 13.6 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Mito_carr PF00153.27 KLO09929.1 - 9.6e-56 185.7 2.3 3.9e-18 65.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.23 KLO09930.1 - 2.8e-22 78.5 0.1 3.7e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KLO09930.1 - 2.8e-22 78.9 0.0 4.3e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KLO09930.1 - 7e-05 22.9 0.8 0.0015 18.6 0.8 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 KLO09930.1 - 0.00078 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 KLO09930.1 - 0.008 16.3 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 APOBEC3 NAD1 PF18778.1 KLO09930.1 - 0.0081 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 KLO09930.1 - 0.016 15.2 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 APOBEC_N PF08210.11 KLO09930.1 - 0.021 14.7 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Inv-AAD PF18785.1 KLO09930.1 - 0.033 14.0 0.1 0.056 13.3 0.1 1.4 1 1 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase APOBEC1 PF18769.1 KLO09930.1 - 0.039 14.2 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 APOBEC1 APOBEC4_like PF18774.1 KLO09930.1 - 0.07 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase NAD2 PF18782.1 KLO09930.1 - 0.15 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Ribonuc_red_sm PF00268.21 KLO09931.1 - 1.3e-06 28.1 0.2 1.8e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain peroxidase PF00141.23 KLO09933.1 - 8.8e-29 100.8 0.0 1.6e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KLO09933.1 - 5.9e-27 93.4 1.1 1.5e-26 92.1 1.1 1.7 1 0 0 1 1 1 1 Fungal peroxidase extension region Glyco_hydro_42 PF02449.15 KLO09933.1 - 0.27 10.5 0.0 0.34 10.2 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase peroxidase PF00141.23 KLO09934.1 - 6.3e-30 104.6 0.2 1.1e-29 103.8 0.2 1.4 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KLO09934.1 - 1.4e-27 95.4 3.9 3e-27 94.4 2.4 2.4 2 0 0 2 2 2 1 Fungal peroxidase extension region Methyltransf_2 PF00891.18 KLO09938.1 - 1.2e-17 63.9 0.0 1.4e-16 60.4 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain HNH_2 PF13391.6 KLO09939.1 - 6.3e-06 26.2 0.2 1.9e-05 24.7 0.2 1.8 1 0 0 1 1 1 1 HNH endonuclease Methyltransf_2 PF00891.18 KLO09940.1 - 2.7e-13 49.7 0.0 4.4e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain p450 PF00067.22 KLO09941.1 - 8e-66 222.7 0.0 9.9e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribo_biogen_C PF04034.13 KLO09941.1 - 0.18 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein, C-terminal Trp_halogenase PF04820.14 KLO09942.1 - 1.6e-31 109.7 0.2 5.4e-29 101.3 0.2 2.6 1 1 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.19 KLO09942.1 - 1.1e-14 54.5 0.0 4.5e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KLO09942.1 - 3.4e-05 24.0 0.4 0.00035 20.7 0.2 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KLO09942.1 - 7.1e-05 22.1 0.2 0.00013 21.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KLO09942.1 - 8.1e-05 22.1 0.5 0.00023 20.7 0.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO09942.1 - 0.00048 19.4 0.0 0.0012 18.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KLO09942.1 - 0.00089 18.4 0.1 0.0015 17.7 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KLO09942.1 - 0.006 15.3 0.1 0.01 14.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KLO09942.1 - 0.017 14.7 0.9 0.031 13.8 0.3 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KLO09942.1 - 0.031 13.5 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO09942.1 - 0.14 12.7 0.0 0.42 11.2 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RhoGAP PF00620.27 KLO09943.1 - 1e-33 116.3 0.0 1.7e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 KLO09943.1 - 4e-31 108.0 0.2 7.2e-31 107.2 0.2 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KLO09943.1 - 1.8e-05 24.5 0.1 3.1e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Nod1 PF17114.5 KLO09943.1 - 0.14 12.3 0.4 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 p450 PF00067.22 KLO09944.1 - 3.8e-55 187.5 0.0 4.5e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO09945.1 - 8.7e-70 235.7 0.0 1e-69 235.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 KLO09946.1 - 6.1e-22 78.0 0.0 4.1e-19 68.7 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Dimerisation PF08100.11 KLO09946.1 - 6.6e-06 26.0 0.2 1.8e-05 24.7 0.2 1.7 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.12 KLO09946.1 - 0.00019 22.1 0.0 0.00057 20.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO09946.1 - 0.05 14.3 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KLO09946.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KLO09946.1 - 0.089 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.13 KLO09946.1 - 0.2 11.1 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 p450 PF00067.22 KLO09947.1 - 5.2e-63 213.4 0.0 6.6e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO09948.1 - 6.1e-32 111.0 0.0 7.8e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO09949.1 - 1.2e-62 212.2 0.0 1.8e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FG-GAP_2 PF14312.6 KLO09949.1 - 0.036 14.3 0.6 0.85 9.9 0.1 2.5 2 0 0 2 2 2 0 FG-GAP repeat Glyco_transf_8 PF01501.20 KLO09950.1 - 3.1e-19 69.5 0.0 4.5e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KLO09950.1 - 0.0091 15.4 0.6 0.02 14.3 0.1 1.7 1 1 1 2 2 2 1 Glucosyltransferase 24 Mannosyl_trans3 PF11051.8 KLO09950.1 - 0.012 15.0 0.1 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 Mannosyltransferase putative Peripla_BP_2 PF01497.18 KLO09950.1 - 0.057 13.0 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Glyco_transf_21 PF13506.6 KLO09950.1 - 0.095 12.2 0.5 0.81 9.1 0.1 2.1 1 1 1 2 2 2 0 Glycosyl transferase family 21 p450 PF00067.22 KLO09951.1 - 2.4e-51 174.9 0.0 7.1e-28 97.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KLO09952.1 - 3.1e-65 220.7 0.0 3.8e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 XPG_N PF00752.17 KLO09954.1 - 6e-24 84.5 0.0 1.1e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KLO09954.1 - 3.8e-23 81.6 0.0 1.1e-22 80.2 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KLO09954.1 - 1e-05 26.0 0.0 2.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.7 KLO09954.1 - 5.6e-05 22.7 0.0 9.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.17 KLO09954.1 - 0.0056 16.7 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KLO09954.1 - 0.0075 16.0 0.0 0.031 14.1 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat HHH_2 PF12826.7 KLO09954.1 - 0.03 14.4 0.0 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 KLO09954.1 - 0.064 13.9 0.0 0.24 12.0 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain TPR_8 PF13181.6 KLO09954.1 - 0.1 12.9 0.1 0.4 11.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat HHH PF00633.23 KLO09954.1 - 0.13 12.2 0.1 0.61 10.1 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif Glyco_hydro_88 PF07470.13 KLO09955.1 - 4.2e-14 52.4 0.3 4.8e-14 52.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Mito_carr PF00153.27 KLO09956.1 - 4e-54 180.5 4.1 5.5e-17 61.5 0.0 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KLO09956.1 - 0.00033 19.9 3.8 0.0017 17.5 1.9 2.7 2 1 0 2 2 2 1 Gammaproteobacterial serine protease PsbX PF06596.11 KLO09956.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.2 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) Rif1_N PF12231.8 KLO09957.1 - 0.035 13.1 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal F-box-like PF12937.7 KLO09960.1 - 0.012 15.5 0.1 0.03 14.2 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KLO09961.1 - 0.00015 21.6 0.4 0.00028 20.7 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09961.1 - 0.00038 20.2 0.2 0.0011 18.8 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO09962.1 - 0.00031 20.6 0.1 0.00059 19.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO09962.1 - 0.0049 16.7 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain SAWADEE PF16719.5 KLO09962.1 - 0.13 12.3 0.5 14 5.7 0.0 2.3 2 0 0 2 2 2 0 SAWADEE domain HpcH_HpaI PF03328.14 KLO09963.1 - 1.6e-31 109.1 0.0 2.1e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IGPS PF00218.21 KLO09963.1 - 0.013 14.6 0.2 0.055 12.6 0.0 1.8 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase DUF2156 PF09924.9 KLO09963.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) PK PF00224.21 KLO09963.1 - 0.019 13.8 2.7 0.23 10.3 0.4 2.2 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain Peptidase_S9 PF00326.21 KLO09964.1 - 1.7e-45 155.1 0.1 2.5e-45 154.6 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KLO09964.1 - 5.2e-06 26.3 0.1 0.1 12.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 KLO09964.1 - 0.0092 14.7 0.1 0.3 9.7 0.1 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Alpha_kinase PF02816.18 KLO09967.1 - 2.1e-05 24.8 0.0 2.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family DUF4800 PF16057.5 KLO09967.1 - 0.032 13.5 0.1 0.043 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) ESSS PF10183.9 KLO09969.1 - 0.53 10.5 5.8 1.4 9.2 5.8 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SURF6 PF04935.12 KLO09971.1 - 4.3e-43 147.5 36.9 4.3e-43 147.5 36.9 2.6 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 KLO09971.1 - 2.4e-19 69.7 7.9 2.4e-19 69.7 7.9 5.8 4 2 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 Hydrolase_6 PF13344.6 KLO09972.1 - 4.1e-29 100.7 0.0 6.4e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO09972.1 - 1.6e-16 60.1 0.0 3e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KLO09972.1 - 3.1e-10 40.7 0.0 4e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KLO09972.1 - 2.2e-07 31.1 0.0 0.019 15.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Ribosomal_L7Ae PF01248.26 KLO09972.1 - 0.012 15.4 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PGP_phosphatase PF09419.10 KLO09972.1 - 0.028 14.0 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase PTPA PF03095.15 KLO09973.1 - 5.2e-127 423.5 0.0 5.9e-127 423.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein 6PF2K PF01591.18 KLO09975.1 - 6e-67 225.2 0.2 8.2e-67 224.8 0.2 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KLO09975.1 - 2.5e-34 118.7 0.0 4.2e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KLO09975.1 - 1.1e-05 25.6 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KLO09975.1 - 0.064 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2110 PF09883.9 KLO09975.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) GBP PF02263.19 KLO09975.1 - 0.18 11.1 0.0 0.39 9.9 0.0 1.5 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Shugoshin_N PF07558.11 KLO09976.1 - 0.00075 19.3 0.4 0.00075 19.3 0.4 1.7 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 KLO09976.1 - 0.0034 17.4 11.3 0.077 13.1 1.3 2.4 2 0 0 2 2 2 2 Basic region leucine zipper CCD48 PF15799.5 KLO09976.1 - 0.0077 14.6 2.9 0.008 14.6 2.9 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 MbeD_MobD PF04899.12 KLO09976.1 - 0.023 14.8 0.3 0.039 14.1 0.3 1.5 1 1 0 1 1 1 0 MbeD/MobD like bZIP_1 PF00170.21 KLO09976.1 - 0.031 14.4 10.7 0.49 10.5 0.4 2.3 1 1 1 2 2 2 0 bZIP transcription factor GAS PF13851.6 KLO09976.1 - 0.093 12.1 3.4 0.12 11.7 3.4 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 KLO09976.1 - 0.11 12.3 0.3 0.11 12.3 0.3 1.9 1 1 1 2 2 2 0 Septum formation initiator GIT_CC PF16559.5 KLO09976.1 - 0.14 12.1 2.3 1.3 9.0 2.3 2.1 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KLO09976.1 - 0.15 12.7 0.2 0.25 12.0 0.2 1.4 1 0 0 1 1 1 0 Initiation control protein YabA TFIIA PF03153.13 KLO09977.1 - 1.6 8.6 20.8 2.2 8.2 20.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short_C2 PF13561.6 KLO09980.1 - 1.9e-58 197.8 2.5 2.4e-58 197.5 2.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO09980.1 - 1e-49 168.7 4.2 1.3e-49 168.3 4.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO09980.1 - 1e-16 61.3 0.6 3.1e-16 59.8 0.4 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KLO09980.1 - 5.3e-05 22.8 0.5 8.3e-05 22.2 0.5 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO09980.1 - 0.00074 19.0 0.1 0.00096 18.6 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF4170 PF13773.6 KLO09980.1 - 0.01 15.9 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) 3HCDH_N PF02737.18 KLO09980.1 - 0.018 14.9 0.8 0.38 10.6 0.2 2.5 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KLO09980.1 - 0.045 13.1 0.0 0.098 12.0 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 KLO09980.1 - 0.051 13.8 0.6 0.16 12.2 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain YAcAr PF10686.9 KLO09980.1 - 0.053 13.5 0.5 0.54 10.3 0.4 2.8 3 1 0 3 3 3 0 YspA, cpYpsA-related SLOG family Vps23_core PF09454.10 KLO09980.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Vps23 core domain DUF4588 PF15251.6 KLO09980.1 - 0.35 10.6 2.8 1.5 8.6 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4588) TIMELESS PF04821.14 KLO09984.1 - 1.9e-81 273.4 0.4 1.9e-81 273.4 0.4 2.4 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 KLO09984.1 - 4.3e-15 55.9 0.1 4.3e-15 55.9 0.1 3.3 3 0 0 3 3 3 1 Timeless protein C terminal region RNA_pol_Rpb4 PF03874.16 KLO09984.1 - 0.61 10.4 16.0 0.19 12.1 1.4 3.8 4 0 0 4 4 4 0 RNA polymerase Rpb4 Methyltr_RsmB-F PF01189.17 KLO09985.1 - 1.8e-29 102.9 0.0 9.5e-27 93.9 0.0 3.3 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F LysM PF01476.20 KLO09987.1 - 1.9e-12 47.0 0.0 1e-05 25.5 0.0 2.6 3 0 0 3 3 3 2 LysM domain Kei1 PF08552.11 KLO09989.1 - 0.039 13.8 0.6 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 7tm_1 PF00001.21 KLO09989.1 - 0.054 12.8 0.9 0.078 12.3 0.9 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4199 PF13858.6 KLO09989.1 - 3.9 7.9 8.7 1.5 9.2 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) Tetraspanin PF00335.20 KLO09989.1 - 5.9 6.5 8.8 5.8 6.6 7.4 1.4 1 1 0 1 1 1 0 Tetraspanin family Ribosomal_L31e PF01198.19 KLO09991.1 - 3.7e-42 142.4 1.2 5.2e-42 142.0 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e CFEM PF05730.11 KLO09992.1 - 5e-13 48.9 12.1 9.1e-13 48.1 12.1 1.4 1 0 0 1 1 1 1 CFEM domain Ribosomal_L34e PF01199.18 KLO09994.1 - 8.7e-44 147.8 3.4 1.4e-43 147.1 3.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e EndIII_4Fe-2S PF10576.9 KLO09994.1 - 0.21 11.9 2.6 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III CAP59_mtransfer PF11735.8 KLO09995.1 - 2.4e-65 220.6 0.0 3.5e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 RCC1_2 PF13540.6 KLO09995.1 - 0.8 9.6 3.3 1.9 8.4 3.3 1.6 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat N2227 PF07942.12 KLO09996.1 - 1.9e-96 322.4 0.0 2.5e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KLO09996.1 - 0.00013 21.8 0.0 0.00024 21.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO09996.1 - 0.00036 21.2 0.0 0.0014 19.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO09996.1 - 0.00061 20.4 0.0 0.071 13.8 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO09996.1 - 0.057 14.1 0.0 1.9 9.2 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain CDC45 PF02724.14 KLO09996.1 - 0.4 8.9 2.3 0.54 8.5 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_5_C PF18564.1 KLO09997.1 - 4e-21 75.3 0.0 9.3e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KLO09997.1 - 5.6e-14 52.2 0.3 1.7e-09 37.6 0.0 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Peptidase_C48 PF02902.19 KLO09998.1 - 0.0015 18.4 0.2 0.0047 16.8 0.0 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain CD99L2 PF12301.8 KLO09998.1 - 0.71 10.2 10.1 0.17 12.2 0.2 3.2 4 0 0 4 4 4 0 CD99 antigen like protein 2 Alpha-amylase PF00128.24 KLO10000.1 - 3.1e-78 263.7 3.0 3.7e-78 263.4 3.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KLO10000.1 - 0.00026 20.2 0.0 0.00037 19.7 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_3 PF00933.21 KLO10001.1 - 1.8e-85 287.2 0.0 2.9e-85 286.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Imm30 PF15565.6 KLO10001.1 - 0.042 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 30 F-box-like PF12937.7 KLO10002.1 - 2.1e-06 27.5 0.0 6.5e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 F-box-like DUF3736 PF12540.8 KLO10002.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3736) F-box-like PF12937.7 KLO10003.1 - 3.7e-06 26.7 4.6 2.7e-05 23.9 1.5 2.8 2 1 0 2 2 2 2 F-box-like F-box-like PF12937.7 KLO10006.1 - 5.2e-06 26.2 0.1 1.2e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO10006.1 - 0.0036 17.2 1.7 0.47 10.4 0.4 2.9 2 0 0 2 2 2 2 F-box domain His_Phos_1 PF00300.22 KLO10008.1 - 2.2e-21 76.4 0.0 1.4e-13 51.0 0.2 3.1 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) SNARE_assoc PF09335.11 KLO10009.1 - 9.5e-09 35.8 3.4 9.5e-09 35.8 3.4 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein MpPF26 PF07666.11 KLO10009.1 - 0.18 11.9 6.7 5.6 7.1 0.1 2.6 2 0 0 2 2 2 0 M penetrans paralogue family 26 DUF3671 PF12420.8 KLO10009.1 - 5.2 7.2 10.3 5.3 7.2 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function CD47 PF04549.14 KLO10009.1 - 7.1 6.8 12.1 0.45 10.7 4.5 2.6 2 1 1 3 3 3 0 CD47 transmembrane region Spt5-NGN PF03439.13 KLO10010.1 - 2.2e-07 30.7 0.0 5.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KLO10010.1 - 2.7e-05 23.9 14.5 0.0021 18.0 0.0 4.7 4 0 0 4 4 4 2 KOW motif SH3_15 PF18346.1 KLO10010.1 - 0.0041 17.4 0.0 6.6 7.1 0.0 3.5 2 1 0 2 2 2 2 Mind bomb SH3 repeat domain SNARE_assoc PF09335.11 KLO10012.1 - 1.8e-13 51.1 8.0 1.8e-13 51.1 8.0 2.3 3 0 0 3 3 3 1 SNARE associated Golgi protein Phage_holin_3_6 PF07332.11 KLO10012.1 - 1.3 9.1 4.8 4.3 7.4 2.6 2.6 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SNARE_assoc PF09335.11 KLO10013.1 - 9.7e-16 58.3 5.8 9.7e-16 58.3 5.8 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein Orf78 PF06024.12 KLO10013.1 - 0.0058 16.9 0.3 0.38 11.1 0.0 2.3 2 0 0 2 2 2 1 Orf78 (ac78) ETRAMP PF09716.10 KLO10013.1 - 0.05 13.7 3.6 0.06 13.4 0.1 2.6 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Phage_holin_6_1 PF09682.10 KLO10013.1 - 0.77 10.2 4.5 5.9 7.4 1.4 2.4 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF4181 PF13789.6 KLO10013.1 - 1.2 9.4 8.3 0.18 12.1 1.9 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) SNARE_assoc PF09335.11 KLO10014.1 - 8e-16 58.6 7.1 8e-16 58.6 7.1 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF4220 PF13968.6 KLO10014.1 - 0.0045 16.5 0.3 0.0045 16.5 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4220) ETRAMP PF09716.10 KLO10014.1 - 0.016 15.3 0.1 0.016 15.3 0.1 2.6 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) SNARE PF05739.19 KLO10014.1 - 0.025 14.6 8.2 3.1 7.9 0.0 2.8 3 0 0 3 3 3 0 SNARE domain YrhC PF14143.6 KLO10014.1 - 0.079 13.1 0.9 1.4 9.1 0.1 2.7 2 1 0 2 2 2 0 YrhC-like protein N6_N4_Mtase PF01555.18 KLO10014.1 - 0.21 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Pox_EPC_I2-L1 PF12575.8 KLO10014.1 - 0.44 10.8 6.7 1.4 9.2 0.8 2.5 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 LMBR1 PF04791.16 KLO10014.1 - 3.1 6.6 8.2 2.3 7.0 1.0 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF2116 PF09889.9 KLO10014.1 - 3.2 7.8 9.0 5.9 7.0 0.2 2.8 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) AMA-1 PF02430.15 KLO10014.1 - 3.4 6.5 5.5 0.54 9.1 0.5 1.8 2 0 0 2 2 2 0 Apical membrane antigen 1 SNARE_assoc PF09335.11 KLO10015.1 - 1.2e-15 58.0 9.7 1.2e-15 58.0 9.7 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4220 PF13968.6 KLO10015.1 - 0.065 12.6 0.8 0.11 11.9 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) SNARE_assoc PF09335.11 KLO10016.1 - 3.8e-15 56.4 10.2 1.2e-14 54.8 8.4 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein Hs1pro-1_C PF07014.12 KLO10016.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus HemY_N PF07219.13 KLO10016.1 - 0.33 11.2 0.1 0.33 11.2 0.1 2.3 4 0 0 4 4 4 0 HemY protein N-terminus SPT_ssu-like PF11779.8 KLO10016.1 - 0.34 10.6 0.1 0.34 10.6 0.1 2.6 3 0 0 3 3 3 0 Small subunit of serine palmitoyltransferase-like Vut_1 PF02592.15 KLO10016.1 - 1.2 9.4 9.9 0.16 12.3 2.8 2.3 1 1 1 2 2 2 0 Putative vitamin uptake transporter CoatB PF10389.9 KLO10016.1 - 1.8 8.4 8.1 12 5.8 2.7 2.7 2 0 0 2 2 2 0 Bacteriophage coat protein B ParE_toxin PF05016.15 KLO10018.1 - 0.12 13.0 0.1 0.19 12.3 0.1 1.4 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE SNARE_assoc PF09335.11 KLO10021.1 - 6.3e-17 62.2 13.0 1.4e-16 61.0 9.6 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein Phage_holin_6_1 PF09682.10 KLO10021.1 - 2.6 8.5 9.3 0.44 11.0 0.5 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) F-box-like PF12937.7 KLO10023.1 - 0.0023 17.8 0.3 0.0058 16.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO10024.1 - 2.7e-06 27.2 0.0 6.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO10024.1 - 6.1e-05 22.8 0.2 6.1e-05 22.8 0.2 2.2 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 KLO10024.1 - 0.038 13.8 1.1 6.3 6.7 0.1 3.5 2 1 0 2 2 2 0 Leucine rich repeat F-box-like PF12937.7 KLO10025.1 - 0.00014 21.7 0.4 0.00075 19.4 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO10025.1 - 0.0071 16.2 1.0 0.0071 16.2 1.0 2.2 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 KLO10025.1 - 0.049 13.4 0.5 0.52 10.1 0.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat HAD_2 PF13419.6 KLO10028.1 - 9.7e-09 35.6 0.0 2.3e-08 34.3 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KLO10028.1 - 4.8e-07 30.3 0.0 1.1e-06 29.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO10028.1 - 4.3e-06 26.7 0.1 7.3e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Med1 PF10744.9 KLO10029.1 - 0.099 11.7 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 DUF4819 PF16090.5 KLO10030.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4819) MULE PF10551.9 KLO10035.1 - 2.9e-08 34.0 0.0 1.1e-07 32.2 0.0 2.1 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 KLO10035.1 - 0.037 13.7 1.4 0.086 12.5 1.4 1.6 1 0 0 1 1 1 0 SWIM zinc finger Amido_AtzD_TrzD PF09663.10 KLO10035.1 - 0.13 11.2 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Med13_C PF06333.12 KLO10038.1 - 2.1 7.5 7.0 2 7.6 2.4 2.2 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain HLH PF00010.26 KLO10041.1 - 2.5e-19 69.0 0.0 2.8e-18 65.6 0.0 2.5 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain Fumarate_red_D PF02313.17 KLO10044.1 - 0.029 14.5 0.4 0.11 12.6 0.2 1.9 1 1 0 1 1 1 0 Fumarate reductase subunit D DUF4795 PF16043.5 KLO10044.1 - 0.1 12.2 0.1 6.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) SLATT_1 PF18181.1 KLO10044.1 - 0.1 12.5 2.5 0.066 13.1 0.6 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4712 PF15830.5 KLO10044.1 - 0.2 11.3 2.0 0.36 10.5 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) Transglut_core3 PF13471.6 KLO10045.1 - 0.15 12.0 2.8 0.17 11.8 0.9 1.9 2 0 0 2 2 2 0 Transglutaminase-like superfamily PAP2 PF01569.21 KLO10046.1 - 1e-17 64.2 9.3 1e-17 64.2 9.3 2.1 2 1 0 2 2 2 1 PAP2 superfamily DUF1440 PF07274.12 KLO10046.1 - 1 9.7 4.5 0.82 10.0 1.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1440) Fer4_5 PF12801.7 KLO10046.1 - 3.4 7.7 11.3 0.24 11.4 2.3 3.2 2 0 0 2 2 2 0 4Fe-4S binding domain SseC PF04888.12 KLO10047.1 - 0.011 15.4 2.5 0.018 14.6 0.4 2.0 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family GMC_oxred_C PF05199.13 KLO10047.1 - 0.16 12.5 0.6 0.33 11.5 0.2 1.8 2 0 0 2 2 2 0 GMC oxidoreductase Phage_tail_APC PF16778.5 KLO10047.1 - 0.41 10.6 0.0 0.41 10.6 0.0 2.6 3 0 0 3 3 3 0 Phage tail assembly chaperone protein Abhydrolase_6 PF12697.7 KLO10048.1 - 5e-11 43.6 0.4 8e-11 43.0 0.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO10048.1 - 3.1e-05 23.7 0.0 0.035 13.7 0.0 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO10051.1 - 5.7e-06 27.1 0.0 7.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family APH PF01636.23 KLO10052.1 - 4.3e-18 66.1 0.0 6.4e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3809 PF12723.7 KLO10052.1 - 0.041 14.2 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) HLH PF00010.26 KLO10053.1 - 1.8e-08 34.2 0.7 4.1e-08 33.1 0.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WD40 PF00400.32 KLO10054.1 - 8.9e-18 64.3 13.4 0.0012 19.7 0.4 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO10054.1 - 2.3e-06 27.8 3.1 0.036 14.4 0.2 4.4 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO10054.1 - 0.00064 18.8 0.0 15 4.4 0.0 4.4 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein SseC PF04888.12 KLO10055.1 - 0.0069 16.0 1.8 0.36 10.4 0.1 2.2 2 0 0 2 2 2 2 Secretion system effector C (SseC) like family DUF2205 PF10224.9 KLO10055.1 - 0.029 14.3 1.7 0.18 11.8 0.1 2.8 3 0 0 3 3 3 0 Short coiled-coil protein LZ3wCH PF18517.1 KLO10055.1 - 0.057 13.5 1.7 0.16 12.1 0.5 2.3 2 0 0 2 2 2 0 Leucine zipper with capping helix domain CBM39 PF15886.5 KLO10055.1 - 0.18 11.7 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) Fungal_trans PF04082.18 KLO10056.1 - 1.2e-13 50.7 0.0 2.1e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO10056.1 - 0.00074 19.6 14.8 0.0015 18.6 14.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 KLO10057.1 - 2.7e-37 127.8 0.0 3.3e-35 121.1 0.0 2.9 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KLO10057.1 - 1.3e-24 86.4 0.0 1.6e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KLO10057.1 - 0.0006 20.0 0.0 0.0022 18.2 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KLO10057.1 - 0.025 15.1 0.0 0.068 13.8 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent zf-RING_2 PF13639.6 KLO10058.1 - 1.2e-06 28.7 8.3 2.4e-06 27.7 8.3 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KLO10058.1 - 0.00039 20.5 6.0 0.00081 19.5 6.0 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KLO10058.1 - 0.0022 18.0 2.7 0.0046 17.0 2.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KLO10058.1 - 0.0024 18.1 7.2 0.0054 17.0 7.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain PEPcase_2 PF14010.6 KLO10058.1 - 0.006 15.1 0.0 0.01 14.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase C1_1 PF00130.22 KLO10058.1 - 0.029 14.3 5.8 0.016 15.1 3.8 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.7 KLO10058.1 - 0.045 13.9 7.2 0.097 12.8 7.2 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 KLO10058.1 - 0.08 13.3 7.5 0.16 12.3 7.5 1.5 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 KLO10058.1 - 0.11 12.1 5.8 0.23 11.1 5.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KLO10058.1 - 0.21 11.5 8.5 0.42 10.5 8.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO10058.1 - 0.25 11.2 7.2 0.51 10.2 7.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 KLO10058.1 - 0.64 10.2 4.4 1.4 9.1 4.4 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger Tfb5 PF06331.12 KLO10062.1 - 0.052 13.5 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Transp_cyt_pur PF02133.15 KLO10063.1 - 7.1e-36 123.9 37.5 1.1e-35 123.3 37.5 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Caveolin PF01146.17 KLO10063.1 - 0.67 9.9 6.6 7.1 6.6 3.2 2.9 1 1 1 2 2 2 0 Caveolin COX7a PF02238.15 KLO10063.1 - 5.5 7.5 5.8 45 4.6 0.8 3.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII DUF2235 PF09994.9 KLO10064.1 - 1.2e-89 300.5 0.0 1.6e-89 300.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peptidase_S10 PF00450.22 KLO10065.1 - 4.6e-111 372.2 0.0 6e-111 371.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 KLO10066.1 - 8.2e-104 348.3 0.0 1e-103 348.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase GST_N_3 PF13417.6 KLO10067.1 - 5.6e-10 39.5 0.0 9.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO10067.1 - 4.7e-08 33.0 0.0 1.1e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KLO10067.1 - 3.2e-07 30.5 0.0 5.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KLO10067.1 - 4.9e-07 30.0 0.0 1.2e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO10067.1 - 8.5e-06 25.9 0.0 5.4e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO10067.1 - 0.00034 20.8 0.0 0.00075 19.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KLO10067.1 - 0.0033 17.6 0.0 0.0058 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 KLO10067.1 - 0.019 15.5 0.0 0.051 14.2 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain adh_short_C2 PF13561.6 KLO10068.1 - 1.9e-57 194.6 0.5 2.1e-57 194.4 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO10068.1 - 4.2e-56 189.5 0.7 5.1e-56 189.2 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO10068.1 - 3.2e-09 37.0 1.3 4.4e-09 36.5 1.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO10068.1 - 0.028 13.9 0.3 0.034 13.6 0.3 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribul_P_3_epim PF00834.19 KLO10068.1 - 0.074 12.4 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family DUF1940 PF09155.10 KLO10068.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) WD40 PF00400.32 KLO10069.1 - 4.1e-28 97.0 19.2 4.5e-05 24.1 0.6 9.7 8 1 1 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO10069.1 - 1.3e-11 44.6 0.0 0.0049 17.1 0.1 6.8 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KLO10069.1 - 1.9e-08 34.0 5.0 0.28 11.2 0.0 5.6 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat NACHT PF05729.12 KLO10069.1 - 8e-07 29.1 0.0 1.9e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KLO10069.1 - 0.00044 19.3 0.1 7.1 5.5 0.0 4.5 3 2 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Zeta_toxin PF06414.12 KLO10069.1 - 0.0024 17.2 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 KLO10069.1 - 0.0033 17.8 0.0 0.012 16.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO10069.1 - 0.011 16.0 0.0 0.049 13.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KLO10069.1 - 0.024 13.8 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 KLO10069.1 - 0.047 12.9 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) VID27 PF08553.10 KLO10069.1 - 0.055 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain AAA PF00004.29 KLO10069.1 - 0.086 13.3 0.0 0.41 11.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MetOD1 PF18546.1 KLO10069.1 - 0.18 11.7 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Metanogen output domain 1 WD40 PF00400.32 KLO10072.1 - 1e-14 54.6 7.2 0.0016 19.3 0.3 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat PD40 PF07676.12 KLO10072.1 - 9.3e-08 31.8 0.0 0.22 11.5 0.0 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KLO10072.1 - 3.8e-07 30.3 0.1 0.094 13.0 0.0 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 KLO10072.1 - 3.6e-06 27.5 0.0 7.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KLO10072.1 - 1.2e-05 25.8 0.0 9.7e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KLO10072.1 - 5.5e-05 23.1 0.2 0.00029 20.8 0.2 2.0 1 1 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KLO10072.1 - 0.00072 18.6 0.0 0.29 10.0 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_22 PF13401.6 KLO10072.1 - 0.0022 18.3 0.0 0.0067 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KLO10072.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KLO10072.1 - 0.055 12.7 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KLO10072.1 - 0.081 12.1 0.1 0.71 9.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 KLO10072.1 - 0.09 12.0 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 KLO10072.1 - 0.1 11.8 0.8 7.3 5.7 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain Nbas_N PF15492.6 KLO10072.1 - 0.12 11.7 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal AAA_19 PF13245.6 KLO10072.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KLO10072.1 - 0.2 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KLO10072.1 - 0.2 12.0 0.0 0.5 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF3087 PF11286.8 KLO10076.1 - 0.028 13.9 0.4 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) DUF3671 PF12420.8 KLO10076.1 - 0.62 10.2 7.5 1.2 9.2 2.1 2.5 2 1 1 3 3 3 0 Protein of unknown function DUF2613 PF11021.8 KLO10078.1 - 0.78 9.9 2.7 0.97 9.6 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) MFA1_2 PF17317.2 KLO10083.1 - 0.053 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 FlgM PF04316.13 KLO10083.1 - 0.088 13.2 5.6 1.9 8.9 0.0 3.8 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM Phage_integrase PF00589.22 KLO10084.1 - 0.012 15.4 0.0 0.19 11.5 0.0 2.2 1 1 0 1 1 1 0 Phage integrase family Peptidase_S10 PF00450.22 KLO10086.1 - 2.7e-64 218.2 0.0 2.8e-63 214.8 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase Methyltransf_2 PF00891.18 KLO10090.1 - 9.6e-18 64.2 0.0 2.9e-17 62.7 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 KLO10090.1 - 0.00023 20.8 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Dimerisation PF08100.11 KLO10090.1 - 0.00065 19.7 0.0 0.0021 18.1 0.0 1.9 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.12 KLO10090.1 - 0.0027 18.4 0.0 0.006 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO10090.1 - 0.032 14.9 0.0 0.063 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RPA_C PF08784.11 KLO10090.1 - 0.052 14.2 0.0 1.1 10.0 0.0 2.4 1 1 1 2 2 2 0 Replication protein A C terminal ECH_1 PF00378.20 KLO10090.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Methyltransf_31 PF13847.6 KLO10090.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KLO10090.1 - 0.23 10.5 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PNKP-ligase_C PF16536.5 KLO10092.1 - 0.098 12.9 0.2 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 PNKP adenylyltransferase domain, C-terminal region Complex1_51K PF01512.17 KLO10093.1 - 2.9e-48 163.6 0.0 4.4e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KLO10093.1 - 5e-32 109.8 0.7 3.6e-31 107.1 0.2 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KLO10093.1 - 1.6e-09 37.5 0.0 4e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 KLO10093.1 - 0.053 13.6 0.4 0.095 12.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) SAM_2 PF07647.17 KLO10094.1 - 4e-09 36.5 0.0 1.5e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KLO10094.1 - 8.4e-08 32.6 0.0 2.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1281 PF06924.11 KLO10094.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) IGR PF09597.10 KLO10094.1 - 0.13 12.4 0.1 0.34 11.0 0.1 1.7 1 0 0 1 1 1 0 IGR protein motif Aldolase_II PF00596.21 KLO10095.1 - 5.5e-26 91.7 0.0 7.1e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain F-box-like PF12937.7 KLO10098.1 - 0.0014 18.5 0.0 0.0034 17.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO10098.1 - 0.082 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 F-box domain Glyco_hydro_15 PF00723.21 KLO10099.1 - 3e-54 184.5 0.0 4.7e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DSPc PF00782.20 KLO10100.1 - 8e-27 93.7 0.0 1.1e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KLO10100.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KLO10100.1 - 0.058 13.7 0.0 0.092 13.1 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Gly_transf_sug PF04488.15 KLO10104.1 - 2.4e-08 34.5 0.0 4.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KLO10104.1 - 0.00041 19.8 0.2 0.00064 19.2 0.2 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Glyco_transf_8 PF01501.20 KLO10105.1 - 1.9e-11 44.0 0.0 1.7e-10 40.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_8 PF01501.20 KLO10106.1 - 1.5e-10 41.1 0.0 1.3e-09 38.0 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 APH PF01636.23 KLO10107.1 - 2.5e-06 27.6 0.0 5e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family p450 PF00067.22 KLO10108.1 - 3.4e-70 237.1 0.0 4.2e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NACHT PF05729.12 KLO10109.1 - 1e-11 45.0 0.0 1.8e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KLO10109.1 - 3e-08 34.0 0.0 5.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO10109.1 - 8.6e-07 29.5 0.0 1.3e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KLO10109.1 - 3.2e-05 24.0 0.0 0.0049 16.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KLO10109.1 - 0.00012 22.6 0.0 0.00029 21.2 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KLO10109.1 - 0.00041 20.0 0.1 0.0016 18.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KLO10109.1 - 0.00065 19.5 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KLO10109.1 - 0.00068 18.9 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 KLO10109.1 - 0.00075 19.5 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KLO10109.1 - 0.0018 18.8 0.0 0.0036 17.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 KLO10109.1 - 0.0019 18.8 0.0 0.0044 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KLO10109.1 - 0.0021 18.4 0.0 0.0037 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KLO10109.1 - 0.0024 18.0 0.1 0.0035 17.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KLO10109.1 - 0.0054 16.0 0.0 0.0072 15.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KLO10109.1 - 0.006 15.9 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.23 KLO10109.1 - 0.0072 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 KLO10109.1 - 0.009 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 NTPase TIP49 PF06068.13 KLO10109.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain APS_kinase PF01583.20 KLO10109.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 KLO10109.1 - 0.024 15.0 0.1 0.059 13.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.18 KLO10109.1 - 0.025 14.3 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ploopntkinase3 PF18751.1 KLO10109.1 - 0.029 14.3 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 KLO10109.1 - 0.044 14.1 0.0 0.069 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KLO10109.1 - 0.05 13.3 0.0 0.074 12.8 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 KLO10109.1 - 0.052 12.9 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Parvo_NS1 PF01057.17 KLO10109.1 - 0.054 12.6 0.1 0.09 11.8 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 KLO10109.1 - 0.061 13.0 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DDE_Tnp_1_assoc PF13808.6 KLO10109.1 - 0.075 13.1 0.5 16 5.6 0.0 2.6 2 1 0 2 2 2 0 DDE_Tnp_1-associated AAA_5 PF07728.14 KLO10109.1 - 0.086 12.8 0.1 0.71 9.9 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2791 PF10923.8 KLO10109.1 - 0.094 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) MeaB PF03308.16 KLO10109.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 KLO10109.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.17 KLO10109.1 - 0.16 12.0 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_PrkA PF08298.11 KLO10109.1 - 0.18 10.7 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain Mg_chelatase PF01078.21 KLO10109.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI GTP_EFTU PF00009.27 KLO10110.1 - 3.7e-66 222.4 1.5 6.3e-66 221.6 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KLO10110.1 - 4e-34 117.0 0.0 1.5e-33 115.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KLO10110.1 - 1.3e-21 76.4 0.0 2.9e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KLO10110.1 - 3.9e-13 49.3 0.0 1e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KLO10110.1 - 2.4e-09 37.5 0.0 8.7e-09 35.7 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KLO10110.1 - 0.0003 20.9 0.2 0.00062 19.8 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Glyco_transf_8 PF01501.20 KLO10111.1 - 1.1e-11 44.8 0.0 4e-10 39.7 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 GTP_EFTU PF00009.27 KLO10112.1 - 4.6e-65 218.8 0.3 7e-65 218.2 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KLO10112.1 - 1.6e-32 111.8 0.0 1.8e-31 108.4 0.0 2.4 1 1 1 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KLO10112.1 - 1.7e-20 72.9 0.0 4.2e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KLO10112.1 - 4.5e-11 42.7 0.0 1.1e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KLO10112.1 - 2.6e-08 34.1 0.0 8.2e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KLO10112.1 - 0.00035 20.6 0.2 0.00088 19.3 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KLO10112.1 - 0.011 15.1 0.1 0.024 14.1 0.1 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 KLO10112.1 - 0.089 12.6 0.0 0.48 10.2 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein WD40 PF00400.32 KLO10113.1 - 5e-42 141.1 6.8 1.4e-06 28.9 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO10113.1 - 1.9e-14 53.7 0.1 0.059 13.7 0.0 5.6 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KLO10113.1 - 1.6e-07 31.0 0.0 2.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KLO10113.1 - 2.3e-05 24.4 0.1 0.00079 19.4 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KLO10113.1 - 0.001 18.5 0.4 0.89 8.8 0.0 3.7 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KLO10113.1 - 0.0043 15.8 1.8 8.4 4.9 0.1 3.8 2 1 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KLO10113.1 - 0.017 14.4 0.0 1.8 7.8 0.0 2.7 2 0 0 2 2 2 0 WD40-like domain Bax1-I PF01027.20 KLO10115.1 - 1.2e-38 133.0 10.8 1.2e-38 133.0 10.8 1.5 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 EVI2A PF05399.11 KLO10116.1 - 0.0034 17.0 1.0 0.0067 16.1 1.0 1.4 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) Podoplanin PF05808.11 KLO10116.1 - 0.0075 16.4 0.9 0.015 15.4 0.9 1.4 1 0 0 1 1 1 1 Podoplanin Orf78 PF06024.12 KLO10116.1 - 0.028 14.7 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 KLO10116.1 - 0.029 14.3 0.2 0.057 13.3 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 KLO10116.1 - 0.04 13.5 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2755 PF10954.8 KLO10116.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) Hydrolase_4 PF12146.8 KLO10118.1 - 2.2e-07 30.4 0.0 0.00011 21.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KLO10118.1 - 0.0014 18.3 0.1 0.0046 16.6 0.1 1.9 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-Tim10_DDP PF02953.15 KLO10119.1 - 5.2e-23 80.5 0.4 6.8e-23 80.1 0.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2334 PF10096.9 KLO10119.1 - 0.16 11.6 0.0 0.18 11.4 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Acyltransferase PF01553.21 KLO10120.1 - 4.9e-23 81.2 0.0 8.4e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KLO10120.1 - 1.7e-07 31.2 0.2 1.3e-06 28.4 0.1 2.3 2 0 0 2 2 2 1 Acyltransferase C-terminus DUF1348 PF07080.11 KLO10121.1 - 2.5e-59 198.8 8.2 3e-59 198.6 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KLO10121.1 - 0.00015 22.4 0.2 0.0002 21.9 0.2 1.5 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KLO10121.1 - 0.0012 19.2 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SGL PF08450.12 KLO10123.1 - 1.3e-26 93.7 0.0 3.1e-26 92.5 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KLO10123.1 - 0.0024 17.9 0.0 0.018 15.2 0.0 2.3 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 KLO10123.1 - 0.012 15.7 0.0 0.24 11.6 0.0 2.5 2 0 0 2 2 2 0 Arylesterase PD40 PF07676.12 KLO10123.1 - 0.046 13.7 1.3 2.5 8.1 0.1 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SBBP PF06739.11 KLO10123.1 - 0.14 12.2 1.0 8 6.6 0.0 2.8 2 0 0 2 2 2 0 Beta-propeller repeat SLD3 PF08639.10 KLO10124.1 - 2.8e-13 49.5 13.1 8.1e-12 44.7 12.1 2.5 1 1 1 2 2 2 1 DNA replication regulator SLD3 MRP_L53 PF10780.9 KLO10125.1 - 0.11 12.7 3.1 2.3 8.5 0.2 3.3 3 0 0 3 3 3 0 39S ribosomal protein L53/MRP-L53 AlaDh_PNT_N PF05222.15 KLO10126.1 - 1.4e-28 99.8 0.0 2.1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KLO10126.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KLO10127.1 - 9.8e-36 123.0 0.0 1.3e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO10127.1 - 7.2e-17 61.7 0.0 8.9e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO10127.1 - 9.5e-05 22.4 0.2 0.00021 21.3 0.2 1.6 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KLO10127.1 - 0.0034 17.6 0.1 0.0055 17.0 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KLO10127.1 - 0.059 12.5 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ras PF00071.22 KLO10129.1 - 6.5e-54 181.9 0.0 7.6e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO10129.1 - 4.7e-21 75.2 0.0 6.6e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO10129.1 - 1.5e-07 31.0 0.0 1.8e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KLO10129.1 - 0.00066 19.3 0.0 0.003 17.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain PBP3 PF18056.1 KLO10130.1 - 5.3e-15 55.5 0.0 9e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Penicillin Binding Protein 3 Domain PliI PF16743.5 KLO10130.1 - 0.022 14.5 0.3 0.059 13.1 0.2 1.7 2 0 0 2 2 2 0 Periplasmic lysozyme inhibitor of I-type lysozyme FG-GAP PF01839.23 KLO10130.1 - 0.076 13.2 3.2 1.4 9.1 1.5 2.7 2 0 0 2 2 2 0 FG-GAP repeat VCBS PF13517.6 KLO10130.1 - 2.7 8.6 9.9 12 6.5 1.5 4.2 4 1 1 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Calreticulin PF00262.18 KLO10131.1 - 4.5e-157 522.6 9.1 6.9e-157 522.0 9.1 1.3 1 0 0 1 1 1 1 Calreticulin family GTP_EFTU PF00009.27 KLO10131.1 - 3.9e-46 157.1 1.8 4.2e-46 157.0 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KLO10131.1 - 9e-38 129.6 4.5 9e-38 129.6 4.5 2.4 2 0 0 2 2 2 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 KLO10131.1 - 6.4e-23 80.6 0.0 1.7e-22 79.3 0.0 1.8 2 0 0 2 2 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 KLO10131.1 - 1.1e-22 80.1 0.0 3.2e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 KLO10131.1 - 2.8e-10 40.4 0.0 6.1e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KLO10131.1 - 2e-05 24.7 0.3 4.2e-05 23.6 0.3 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KLO10131.1 - 3e-05 24.0 0.0 0.00021 21.3 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II SRPRB PF09439.10 KLO10131.1 - 0.0088 15.5 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KLO10131.1 - 0.15 11.6 0.1 0.35 10.4 0.1 1.6 1 0 0 1 1 1 0 Ras family Dynamin_N PF00350.23 KLO10131.1 - 1.4 8.9 6.7 3.8 7.5 0.4 3.3 3 1 1 4 4 4 0 Dynamin family RNase_T PF00929.24 KLO10132.1 - 0.0027 18.3 0.0 0.034 14.7 0.0 2.2 2 0 0 2 2 2 1 Exonuclease p450 PF00067.22 KLO10133.1 - 2.8e-55 187.9 0.0 3.7e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KLO10134.1 - 0.00063 19.8 13.2 0.00075 19.6 13.2 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps5 PF09325.10 KLO10135.1 - 3.8e-15 56.1 1.0 5.1e-15 55.7 1.0 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KLO10135.1 - 5.7e-10 39.2 0.1 1.4e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 PX domain Ofd1_CTDD PF10637.9 KLO10137.1 - 1.6e-60 204.6 0.0 4.5e-60 203.2 0.0 1.6 1 1 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term RRM_1 PF00076.22 KLO10138.1 - 1.7e-13 50.2 0.1 3.4e-05 23.6 0.0 4.1 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribonuclease_3 PF00636.26 KLO10139.1 - 6.6e-41 139.2 0.2 1.2e-19 70.9 0.1 3.3 3 1 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KLO10139.1 - 2.5e-23 82.6 0.1 1.3e-09 38.3 0.0 4.5 4 0 0 4 4 4 4 Ribonuclease-III-like Dicer_dimer PF03368.14 KLO10139.1 - 2.9e-14 53.0 0.3 1.7e-13 50.5 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KLO10139.1 - 3.7e-08 33.7 0.0 9.1e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAZ PF02170.22 KLO10139.1 - 8.4e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 PAZ domain COX7C PF02935.16 KLO10140.1 - 1.1e-16 60.8 0.2 1.2e-16 60.7 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Aldedh PF00171.22 KLO10141.1 - 5.2e-179 595.6 0.1 5.8e-179 595.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SpoIIAA-like PF11964.8 KLO10141.1 - 0.12 13.4 0.0 14 6.8 0.0 2.6 2 0 0 2 2 2 0 SpoIIAA-like Phage_H_T_join PF05521.11 KLO10141.1 - 0.19 12.3 0.1 0.72 10.4 0.0 2.0 2 0 0 2 2 2 0 Phage head-tail joining protein Zn_clus PF00172.18 KLO10142.1 - 3.9e-06 26.9 13.2 5.9e-06 26.3 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 KLO10143.1 - 1.1e-60 204.4 0.0 1.6e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KLO10143.1 - 2.6e-08 33.4 0.2 7.5e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PAP_central PF04928.17 KLO10144.1 - 2.7e-25 88.8 0.0 4.9e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain 2_5_RNA_ligase2 PF13563.6 KLO10144.1 - 5.9e-24 84.7 0.0 1.1e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily MJ1316 PF04457.12 KLO10144.1 - 5.2e-20 72.0 0.3 1.4e-19 70.6 0.3 1.8 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain LigT_PEase PF02834.16 KLO10144.1 - 4.5e-09 36.4 0.0 0.00072 19.7 0.0 2.6 2 0 0 2 2 2 2 LigT like Phosphoesterase Exo_endo_phos PF03372.23 KLO10144.1 - 9.5e-07 28.6 0.8 2.8e-06 27.0 0.1 2.2 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 KLO10144.1 - 0.00016 21.9 0.0 0.00054 20.2 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.6 KLO10144.1 - 0.17 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) AhpC-TSA PF00578.21 KLO10145.1 - 7.9e-29 100.1 0.0 1e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KLO10145.1 - 1.1e-13 51.2 0.0 1.4e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KLO10145.1 - 5.2e-11 42.2 0.0 9.1e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ssu72 PF04722.13 KLO10146.1 - 9.1e-85 283.0 0.0 1.3e-84 282.5 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein F-box-like PF12937.7 KLO10147.1 - 0.00041 20.2 0.9 0.0028 17.5 0.1 2.5 2 0 0 2 2 2 1 F-box-like Nop PF01798.18 KLO10148.1 - 1.1e-72 244.3 0.0 1.9e-72 243.5 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KLO10148.1 - 2.2e-40 138.3 4.9 4.2e-40 137.4 4.9 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain NifU_N PF01592.16 KLO10149.1 - 1.5e-52 177.1 0.0 2.2e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain Zot PF05707.12 KLO10150.1 - 8e-06 25.6 0.0 4.8e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 KLO10150.1 - 2.1e-05 24.8 0.1 0.035 14.4 0.0 2.9 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KLO10150.1 - 0.0018 18.7 0.0 0.69 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KLO10150.1 - 0.002 18.5 0.0 0.06 13.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KLO10150.1 - 0.0098 15.3 0.0 0.028 13.8 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KLO10150.1 - 0.03 13.6 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.17 KLO10150.1 - 0.039 14.0 0.1 0.98 9.5 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain DUF853 PF05872.12 KLO10150.1 - 0.066 11.8 0.0 0.066 11.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_33 PF13671.6 KLO10150.1 - 0.076 13.2 0.1 0.47 10.6 0.0 2.3 2 1 1 3 3 3 0 AAA domain DUF4630 PF15443.6 KLO10150.1 - 0.078 13.1 0.4 0.17 12.1 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) DUF2075 PF09848.9 KLO10150.1 - 0.12 11.6 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Retinal PF15449.6 KLO10150.1 - 0.74 7.5 9.1 1 7.1 9.1 1.1 1 0 0 1 1 1 0 Retinal protein CDC27 PF09507.10 KLO10150.1 - 0.87 8.9 9.2 1.2 8.5 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Methyltransf_8 PF05148.15 KLO10151.1 - 2e-66 224.0 0.0 3.4e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KLO10151.1 - 1.9e-07 31.7 0.0 4.7e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO10151.1 - 8.7e-06 26.4 0.0 2.8e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO10151.1 - 0.00019 21.3 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO10151.1 - 0.0019 18.0 0.1 0.0099 15.7 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO10151.1 - 0.0025 18.5 0.1 0.025 15.3 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 KLO10151.1 - 0.094 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 KLO10151.1 - 0.14 11.7 0.1 1.9 8.0 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase small domain UPRTase PF14681.6 KLO10152.1 - 2.8e-66 222.9 0.0 3.2e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase FAD_binding_1 PF00667.20 KLO10153.1 - 3.4e-54 183.7 0.0 5.1e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KLO10153.1 - 2.1e-07 31.6 0.0 4.7e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 KLO10153.1 - 1.2e-05 25.5 0.0 2.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II FAD_binding_6 PF00970.24 KLO10153.1 - 0.035 14.5 0.0 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain POR PF01558.18 KLO10153.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Glyco_hydro_9 PF00759.19 KLO10154.1 - 2.8e-104 349.8 9.5 3.3e-104 349.6 9.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 SKG6 PF08693.10 KLO10154.1 - 0.0081 15.5 1.4 0.017 14.5 1.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain F-box-like PF12937.7 KLO10155.1 - 1e-05 25.3 0.1 3.4e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 F-box-like GFO_IDH_MocA PF01408.22 KLO10156.1 - 4.7e-19 69.4 0.0 7.9e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KLO10156.1 - 2.4e-08 34.0 0.0 5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KLO10156.1 - 0.11 13.1 0.0 0.21 12.3 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain WD40 PF00400.32 KLO10157.1 - 6.6e-14 52.1 9.7 1.3e-05 25.8 0.8 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.11 KLO10157.1 - 5.4e-05 23.2 0.0 0.019 14.8 0.1 2.7 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KLO10157.1 - 0.00072 19.8 0.2 2 8.8 0.0 4.1 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KLO10157.1 - 0.014 13.9 0.0 0.16 10.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain IKI3 PF04762.12 KLO10157.1 - 0.071 11.1 0.0 0.6 8.0 0.0 2.1 2 0 0 2 2 2 0 IKI3 family PTPRCAP PF15713.5 KLO10157.1 - 0.13 12.5 7.1 0.43 10.9 7.1 1.9 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PQQ_3 PF13570.6 KLO10157.1 - 0.18 12.4 1.6 1 10.0 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain BBS2_N PF14781.6 KLO10157.1 - 0.21 11.5 0.0 5.1 7.1 0.0 2.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal DUF1647 PF07801.11 KLO10157.1 - 0.22 11.3 0.0 0.93 9.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) Tti2 PF10521.9 KLO10158.1 - 4.9e-46 157.5 0.0 6e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Tti2 family WD40 PF00400.32 KLO10159.1 - 6.5e-08 33.1 4.5 0.034 15.0 0.1 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat GFO_IDH_MocA PF01408.22 KLO10161.1 - 2.4e-18 67.1 0.0 3.9e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KLO10161.1 - 6.4e-10 39.1 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KLO10161.1 - 0.0016 19.1 0.0 0.0031 18.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KLO10162.1 - 7.7e-18 65.5 0.0 1.3e-17 64.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KLO10162.1 - 1e-08 35.2 0.0 2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KLO10162.1 - 0.0049 17.5 0.0 0.018 15.7 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain ubiquitin PF00240.23 KLO10163.1 - 2.3e-07 30.5 0.0 4.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KLO10163.1 - 0.02 15.5 0.0 0.048 14.2 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain MARVEL PF01284.23 KLO10164.1 - 1.4e-10 41.4 9.1 1.4e-10 41.4 9.1 2.0 1 1 1 2 2 2 1 Membrane-associating domain SARAF PF06682.12 KLO10164.1 - 0.039 13.6 0.1 0.069 12.8 0.1 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PDR_CDR PF06422.12 KLO10164.1 - 2.4 8.1 4.5 0.59 10.1 0.2 2.2 2 1 1 3 3 3 0 CDR ABC transporter MBOAT PF03062.19 KLO10167.1 - 2.8e-41 142.0 3.1 2.8e-41 142.0 3.1 2.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF5056 PF16479.5 KLO10167.1 - 1.3 9.3 4.8 1.9 8.8 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5056) F-box-like PF12937.7 KLO10168.1 - 3.3e-06 26.9 2.4 5.1e-05 23.1 1.9 3.1 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO10168.1 - 0.16 12.5 4.4 12 6.5 0.6 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Brix PF04427.18 KLO10169.1 - 1.8e-30 106.5 1.3 2.5e-30 106.1 1.3 1.2 1 0 0 1 1 1 1 Brix domain DUF2517 PF10725.9 KLO10169.1 - 0.03 14.1 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) p450 PF00067.22 KLO10170.1 - 3.9e-78 263.2 0.0 5.6e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KLO10170.1 - 1.5e-23 83.6 0.0 2.8e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KLO10170.1 - 5.5e-22 78.5 0.0 1.1e-21 77.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KLO10170.1 - 1.6e-09 38.4 0.0 3.7e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain RRM_1 PF00076.22 KLO10172.1 - 6.3e-16 58.0 0.0 8.4e-16 57.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KLO10172.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KLO10172.1 - 0.14 12.0 0.0 0.38 10.7 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif Ribosomal_L18 PF17135.4 KLO10173.1 - 2.3e-90 301.0 1.6 2.5e-90 300.9 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KLO10173.1 - 0.0018 19.0 0.0 0.0048 17.6 0.0 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Histone PF00125.24 KLO10175.1 - 1.8e-45 154.5 0.3 2.3e-45 154.2 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KLO10175.1 - 0.00064 19.8 0.1 0.001 19.2 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KLO10175.1 - 0.011 15.9 0.5 0.092 13.1 0.1 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KLO10175.1 - 0.018 15.4 0.1 0.029 14.8 0.1 1.4 1 0 0 1 1 1 0 CENP-S protein TFIID-31kDa PF02291.15 KLO10175.1 - 0.043 13.9 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Med9 PF07544.13 KLO10176.1 - 0.09 12.9 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TRAM_LAG1_CLN8 PF03798.16 KLO10177.1 - 2.8e-33 115.3 25.2 2.8e-33 115.3 25.2 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KLO10177.1 - 5.1e-19 67.7 0.2 1.6e-18 66.1 0.2 1.9 1 0 0 1 1 1 1 TRAM1-like protein F-box-like PF12937.7 KLO10178.1 - 2e-07 30.8 0.4 5.4e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO10178.1 - 0.039 13.8 0.5 0.039 13.8 0.5 3.2 3 1 0 3 3 3 0 F-box domain DUF3709 PF12493.8 KLO10178.1 - 0.1 12.7 0.1 0.1 12.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3709) F-box-like PF12937.7 KLO10179.1 - 1.4e-07 31.3 5.0 1.6e-07 31.1 0.0 3.2 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 KLO10179.1 - 0.07 13.0 0.2 0.07 13.0 0.2 2.7 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO10180.1 - 8.8e-09 35.1 0.2 3e-08 33.4 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO10181.1 - 1.3e-05 25.0 0.4 4.7e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO10181.1 - 0.011 15.6 1.5 0.17 11.8 0.2 3.4 2 1 0 2 2 2 0 F-box domain MIT_C PF16565.5 KLO10181.1 - 0.086 12.8 0.2 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 Phospholipase D-like domain at C-terminus of MIT Glyco_hydro_10 PF00331.20 KLO10182.1 - 1.2e-95 320.3 0.0 1.5e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBFD_NFYB_HMF PF00808.23 KLO10184.1 - 2.8e-16 59.5 0.3 2.8e-16 59.5 0.3 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KLO10184.1 - 6e-05 23.4 1.9 0.00023 21.5 0.1 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 KLO10184.1 - 0.0012 18.9 0.2 0.0018 18.3 0.2 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF1360 PF07098.11 KLO10184.1 - 0.013 15.4 0.0 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) Cyt-b5 PF00173.28 KLO10185.1 - 2.4e-13 50.0 0.0 3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SLD5_C PF16922.5 KLO10188.1 - 3e-10 40.1 0.0 7.1e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KLO10188.1 - 0.00026 21.4 0.6 0.00046 20.6 0.6 1.4 1 0 0 1 1 1 1 GINS complex protein DUF959 PF06121.14 KLO10188.1 - 0.12 12.7 4.6 0.21 11.9 4.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) TATR PF03430.13 KLO10188.1 - 0.16 10.3 0.1 0.23 9.8 0.1 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator CENP-T_C PF15511.6 KLO10190.1 - 4.9e-07 29.9 0.0 5.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KLO10190.1 - 3.4e-05 23.9 0.1 4.8e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KLO10190.1 - 0.0002 21.6 0.0 0.00026 21.3 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KLO10190.1 - 0.00085 19.6 0.1 0.0016 18.7 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KLO10190.1 - 0.00094 19.5 0.2 0.0011 19.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KLO10190.1 - 0.058 13.5 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KLO10190.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Hydrophobin PF01185.18 KLO10192.1 - 4e-12 46.6 8.2 5.3e-12 46.2 8.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.12 KLO10192.1 - 6.8 7.5 10.4 8.2 7.2 0.6 2.5 3 0 0 3 3 3 0 Ion channel inhibitory toxin Methyltransf_23 PF13489.6 KLO10193.1 - 1.6e-11 44.3 0.0 2e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO10193.1 - 1.9e-06 28.5 0.0 6.9e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO10193.1 - 2.8e-05 24.8 0.0 0.00013 22.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO10193.1 - 8.3e-05 23.2 0.0 0.0015 19.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO10193.1 - 0.00042 20.1 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain RrnaAD PF00398.20 KLO10193.1 - 0.0029 16.7 0.0 0.0046 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 KLO10193.1 - 0.055 13.0 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KLO10194.1 - 2e-13 50.5 0.0 3.2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO10194.1 - 1.3e-05 25.7 0.0 0.0018 18.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO10194.1 - 9.3e-05 23.1 0.0 0.00049 20.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO10194.1 - 0.0044 17.7 0.0 0.11 13.2 0.0 2.3 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO10194.1 - 0.013 15.3 0.0 4.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 KLO10194.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KLO10194.1 - 0.064 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 KLO10195.1 - 3.7e-38 131.4 0.0 6.1e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO10195.1 - 1.5e-33 116.2 0.0 2.4e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_9 PF14604.6 KLO10195.1 - 8e-13 48.0 0.3 2.6e-07 30.4 0.2 3.3 3 1 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KLO10195.1 - 2.5e-12 46.2 2.6 5.4e-08 32.3 0.1 3.2 2 1 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KLO10195.1 - 3.4e-06 26.7 0.1 0.00026 20.6 0.1 2.5 2 0 0 2 2 2 1 Variant SH3 domain Pkinase_fungal PF17667.1 KLO10195.1 - 0.00032 19.6 0.0 0.00058 18.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO10195.1 - 0.0031 17.5 0.0 0.059 13.3 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO10195.1 - 0.0038 16.8 0.4 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 KLO10195.1 - 0.0082 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO10195.1 - 0.044 13.1 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 KLO10196.1 - 0.00011 22.1 0.3 0.00011 22.1 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO10196.1 - 0.028 14.3 0.5 0.14 12.1 0.5 2.2 1 0 0 1 1 1 0 F-box domain Hydrophobin PF01185.18 KLO10198.1 - 2.1e-24 85.9 10.8 3.1e-24 85.4 10.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin F-box-like PF12937.7 KLO10200.1 - 2.3e-07 30.6 0.9 2.9e-06 27.1 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO10200.1 - 0.011 15.6 0.1 0.011 15.6 0.1 3.9 4 1 0 4 4 4 0 F-box domain F-box-like PF12937.7 KLO10201.1 - 1.4e-07 31.3 3.6 8e-07 28.9 0.0 3.2 3 1 0 3 3 3 1 F-box-like Pesticin PF16754.5 KLO10201.1 - 0.034 14.1 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial toxin homologue of phage lysozyme, C-term F-box PF00646.33 KLO10201.1 - 0.051 13.5 3.1 0.5 10.3 0.2 3.5 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO10202.1 - 0.014 15.3 0.2 0.25 11.3 0.0 2.5 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 KLO10203.1 - 1.6e-06 27.9 0.7 7.9e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO10203.1 - 0.36 10.8 5.2 3.1 7.8 0.1 3.7 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO10204.1 - 6.2e-07 29.2 0.1 6.1e-06 26.0 0.1 2.3 2 0 0 2 2 2 1 F-box-like ThrE_2 PF12821.7 KLO10204.1 - 0.16 12.1 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE F-box PF00646.33 KLO10204.1 - 1.1 9.2 4.0 0.91 9.5 0.6 2.7 2 1 0 2 2 2 0 F-box domain ABC_tran PF00005.27 KLO10205.1 - 3.6e-35 121.4 0.0 4.5e-17 62.9 0.0 2.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KLO10205.1 - 3.7e-13 49.9 0.9 0.0051 16.7 0.0 4.3 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KLO10205.1 - 1.5e-10 40.9 2.5 0.001 18.5 0.2 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KLO10205.1 - 7.1e-06 26.0 0.3 0.0083 16.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KLO10205.1 - 3.4e-05 24.1 0.0 0.008 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO10205.1 - 4.8e-05 23.8 0.0 0.053 13.9 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KLO10205.1 - 0.00015 21.6 0.9 0.29 10.8 0.7 2.5 2 1 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 KLO10205.1 - 0.00041 20.3 0.0 0.03 14.3 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_23 PF13476.6 KLO10205.1 - 0.00062 20.3 0.1 0.16 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KLO10205.1 - 0.00089 19.2 0.2 0.14 12.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KLO10205.1 - 0.0067 16.9 0.0 3.6 8.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KLO10205.1 - 0.0079 16.3 0.3 1.4 9.0 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KLO10205.1 - 0.01 15.5 2.3 1.9 8.3 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 KLO10205.1 - 0.013 15.2 0.8 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KLO10205.1 - 0.013 15.5 0.1 2.9 7.9 0.0 3.2 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KLO10205.1 - 0.016 15.0 0.3 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KLO10205.1 - 0.019 15.2 0.0 5.6 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KLO10205.1 - 0.02 15.0 0.0 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KLO10205.1 - 0.021 15.4 0.0 1.3 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KLO10205.1 - 0.022 14.3 0.1 0.35 10.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 KLO10205.1 - 0.032 13.4 0.0 4.3 6.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.6 KLO10205.1 - 0.032 14.4 0.1 13 6.1 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 KLO10205.1 - 0.044 14.0 0.3 0.34 11.2 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KLO10205.1 - 0.054 13.9 0.0 18 5.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 KLO10205.1 - 0.1 12.7 0.1 21 5.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KLO10205.1 - 0.13 11.9 0.2 14 5.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Thymidylate_kin PF02223.17 KLO10205.1 - 0.15 11.7 0.1 2.7 7.6 0.0 2.7 3 1 0 3 3 2 0 Thymidylate kinase PduV-EutP PF10662.9 KLO10205.1 - 0.15 11.8 1.0 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 KLO10205.1 - 0.16 11.3 0.2 1 8.8 0.0 2.4 2 1 1 3 3 3 0 Bacterial TniB protein DLIC PF05783.11 KLO10205.1 - 0.17 10.7 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) F-box-like PF12937.7 KLO10206.1 - 7.2e-07 29.0 0.0 4.8e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO10206.1 - 0.15 12.0 3.5 0.64 10.0 0.5 3.5 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO10207.1 - 8.9e-09 35.1 1.5 1.9e-07 30.9 0.1 2.6 2 0 0 2 2 2 1 F-box-like BLOC1_2 PF10046.9 KLO10207.1 - 0.034 14.4 0.9 2.9 8.3 0.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 F-box-like PF12937.7 KLO10208.1 - 0.0001 22.1 0.0 0.0001 22.1 0.0 2.3 3 0 0 3 3 3 1 F-box-like RRM_1 PF00076.22 KLO10208.1 - 0.00039 20.2 0.0 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box PF00646.33 KLO10208.1 - 0.035 14.0 3.8 0.092 12.6 0.1 3.1 2 1 0 2 2 2 0 F-box domain Pesticin PF16754.5 KLO10208.1 - 0.15 12.0 0.0 0.63 10.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial toxin homologue of phage lysozyme, C-term F-box-like PF12937.7 KLO10209.1 - 1e-05 25.3 0.0 0.00032 20.5 0.0 3.2 3 0 0 3 3 3 1 F-box-like DHR10 PF18595.1 KLO10209.1 - 0.15 12.1 1.8 0.26 11.3 1.8 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain F-box-like PF12937.7 KLO10210.1 - 0.00096 19.0 0.3 0.00096 19.0 0.3 2.8 3 0 0 3 3 3 1 F-box-like DUF1736 PF08409.11 KLO10210.1 - 0.1 12.6 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) Helicase_C PF00271.31 KLO10216.1 - 8.7e-13 48.6 0.0 2e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO10216.1 - 2.8e-07 30.5 0.0 8.3e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KLO10216.1 - 0.00034 21.3 0.1 0.00078 20.1 0.1 1.6 1 0 0 1 1 1 1 RecQ zinc-binding DEAD PF00270.29 KLO10217.1 - 3.1e-12 46.6 0.0 3.4e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase SecA_DEAD PF07517.14 KLO10217.1 - 0.00027 20.4 0.0 0.00028 20.3 0.0 1.1 1 0 0 1 1 1 1 SecA DEAD-like domain ResIII PF04851.15 KLO10217.1 - 0.16 12.0 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Na_Ca_ex PF01699.24 KLO10218.1 - 4.5e-13 49.4 24.0 5.9e-09 36.1 9.1 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2298 PF10060.9 KLO10218.1 - 0.041 12.6 13.1 0.013 14.3 1.7 2.3 1 1 1 2 2 2 0 Uncharacterized membrane protein (DUF2298) OppC_N PF12911.7 KLO10218.1 - 0.051 13.6 2.7 15 5.6 0.0 4.8 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C tRNA-synt_1b PF00579.25 KLO10221.1 - 1.4e-57 195.3 0.0 4.8e-57 193.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) AAA_assoc_2 PF16193.5 KLO10223.1 - 0.19 12.1 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA C-terminal domain NACHT PF05729.12 KLO10224.1 - 2.6e-09 37.2 0.0 5.9e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO10224.1 - 0.0012 19.3 0.0 0.0037 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO10224.1 - 0.14 12.5 0.0 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KLO10225.1 - 8.6e-17 61.8 0.0 5.9e-16 59.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KLO10225.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KLO10225.1 - 0.022 15.1 0.3 0.062 13.7 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KLO10225.1 - 0.024 14.9 2.1 0.16 12.2 0.4 2.4 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KLO10225.1 - 0.11 13.0 0.0 0.47 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KLO10225.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin F-box-like PF12937.7 KLO10227.1 - 1.4e-05 24.9 0.0 7.7e-05 22.5 0.0 2.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO10227.1 - 0.15 12.0 1.1 3.2 7.7 0.1 2.8 2 0 0 2 2 2 0 F-box domain eIF-3_zeta PF05091.12 KLO10228.1 - 2.6e-193 643.7 0.0 3.1e-193 643.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rhomboid PF01694.22 KLO10229.1 - 7e-06 26.1 6.8 1.2e-05 25.3 6.8 1.3 1 0 0 1 1 1 1 Rhomboid family CUE PF02845.16 KLO10229.1 - 2.9e-05 23.6 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF1180 PF06679.12 KLO10229.1 - 0.029 14.8 2.7 0.042 14.3 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) ApbA PF02558.16 KLO10230.1 - 4.5e-23 81.6 0.0 6.7e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KLO10230.1 - 2.8e-21 76.0 0.1 9.8e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal GATA PF00320.27 KLO10235.1 - 4.6e-08 32.5 4.1 8.2e-08 31.7 4.1 1.4 1 0 0 1 1 1 1 GATA zinc finger Haem_bd PF14376.6 KLO10235.1 - 0.15 12.0 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 Haem-binding domain BES1_N PF05687.13 KLO10235.1 - 2.4 8.6 5.4 4 7.8 4.3 1.9 1 1 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal ING PF12998.7 KLO10236.1 - 1.4e-08 35.2 0.0 9.7e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KLO10236.1 - 1.6e-05 24.7 5.8 2.5e-05 24.1 5.8 1.3 1 0 0 1 1 1 1 PHD-finger CCDC24 PF15669.5 KLO10236.1 - 0.013 15.4 0.1 0.013 15.4 0.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family zf-HC5HC2H PF13771.6 KLO10236.1 - 0.019 15.2 0.1 0.041 14.1 0.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain NOA36 PF06524.12 KLO10236.1 - 0.12 11.7 4.2 0.21 10.9 4.2 1.4 1 0 0 1 1 1 0 NOA36 protein TRP PF06011.12 KLO10237.1 - 1.4e-32 113.0 11.2 5.9e-32 110.9 11.2 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KLO10237.1 - 0.0022 18.4 0.1 0.011 16.1 0.1 2.0 2 0 0 2 2 2 1 ML-like domain NeA_P2 PF12312.8 KLO10237.1 - 0.076 12.5 2.6 0.15 11.5 2.6 1.5 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein CNH PF00780.22 KLO10238.1 - 2e-05 24.4 0.0 0.059 13.0 0.0 2.3 2 0 0 2 2 2 2 CNH domain Kelch_4 PF13418.6 KLO10239.1 - 2.3e-17 62.7 15.1 0.0038 17.2 0.0 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KLO10239.1 - 1.3e-14 54.0 15.9 0.0068 16.7 0.2 6.8 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KLO10239.1 - 9.7e-07 28.9 8.2 2.6 8.5 0.1 6.0 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KLO10239.1 - 5.7e-06 26.2 3.1 2.9 8.0 0.0 4.9 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KLO10239.1 - 9.3e-06 25.1 4.0 1.5 8.5 0.0 5.4 6 0 0 6 6 6 3 Kelch motif Peptidase_S49_N PF08496.10 KLO10240.1 - 1.3 9.1 6.3 2.8 8.0 6.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HSP90 PF00183.18 KLO10241.1 - 1.5e-138 463.0 8.2 1.9e-138 462.6 8.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 KLO10241.1 - 1.6e-07 31.2 0.0 4e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KLO10241.1 - 7e-06 26.5 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NurA PF09376.10 KLO10241.1 - 0.11 12.1 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 NurA domain AAA PF00004.29 KLO10242.1 - 3.6e-16 59.8 0.0 8.6e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KLO10242.1 - 0.0099 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KLO10242.1 - 0.015 15.6 1.3 0.065 13.5 0.2 2.2 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 KLO10242.1 - 0.042 14.2 0.0 0.091 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KLO10242.1 - 0.058 12.7 0.1 0.14 11.4 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 KLO10242.1 - 0.11 11.9 0.2 0.27 10.5 0.2 1.6 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 KLO10242.1 - 0.15 12.6 0.0 0.41 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KLO10243.1 - 6.1e-09 36.0 0.0 1.6e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO10243.1 - 0.0013 19.2 0.0 0.0056 17.1 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain Goodbye PF17109.5 KLO10243.1 - 0.015 15.8 0.0 0.043 14.3 0.0 1.8 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain DUF2153 PF09921.9 KLO10244.1 - 0.047 13.5 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) DUF572 PF04502.13 KLO10245.1 - 8.2e-67 226.2 0.5 9.8e-67 225.9 0.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Hydrolase_4 PF12146.8 KLO10245.1 - 0.029 13.6 0.1 0.05 12.9 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ribosomal_S10 PF00338.22 KLO10246.1 - 2.2e-23 82.3 0.5 2.7e-23 82.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pex14_N PF04695.13 KLO10247.1 - 1.7e-09 38.6 0.1 1.7e-09 38.6 0.1 3.6 4 1 1 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_1 PF07690.16 KLO10248.1 - 4.1e-34 118.1 9.1 4.1e-34 118.1 9.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KLO10248.1 - 3.1e-05 23.5 0.1 3.1e-05 23.5 0.1 2.3 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB HCMV_UL124 PF17609.2 KLO10249.1 - 0.0069 16.6 5.4 0.0069 16.6 5.4 4.4 3 1 2 5 5 5 1 Family of unknown function TFIIA PF03153.13 KLO10249.1 - 0.066 13.2 21.0 0.089 12.8 3.7 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 KLO10249.1 - 0.068 12.5 12.6 0.14 11.4 12.6 1.5 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.7 KLO10249.1 - 2.3 6.3 8.2 3.9 5.5 8.2 1.5 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PRCC PF10253.9 KLO10249.1 - 4 8.2 29.4 0.057 14.2 9.1 3.2 3 0 0 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting Utp14 PF04615.13 KLO10249.1 - 6.8 5.1 13.9 0.43 9.1 8.9 1.4 2 0 0 2 2 2 0 Utp14 protein Glyco_hydro_7 PF00840.20 KLO10251.1 - 1e-205 683.5 17.4 1.4e-205 683.1 17.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KLO10251.1 - 3e-12 46.3 12.7 3e-12 46.3 12.7 4.5 3 1 0 3 3 3 1 Fungal cellulose binding domain p450 PF00067.22 KLO10252.1 - 3.9e-72 243.5 0.0 4.8e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO10253.1 - 7.8e-42 143.6 0.0 8.7e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Retrotran_gag_2 PF14223.6 KLO10257.1 - 1.5e-08 34.4 0.0 1.6e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PBECR2 PF18810.1 KLO10257.1 - 0.13 12.6 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 K_trans PF02705.16 KLO10263.1 - 7.1e-177 589.1 10.3 8.7e-177 588.8 10.3 1.1 1 0 0 1 1 1 1 K+ potassium transporter p450 PF00067.22 KLO10267.1 - 2.9e-67 227.4 0.0 7.3e-67 226.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 AChE_tetra PF08674.10 KLO10268.1 - 4.6 7.0 6.2 23 4.8 0.4 2.4 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain OPT PF03169.15 KLO10272.1 - 1.5e-189 631.6 61.5 1.7e-189 631.4 61.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 KLO10273.1 - 1.9e-183 611.4 58.0 1.5e-167 558.9 46.2 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Pep1_7 PF17232.2 KLO10275.1 - 0.005 17.3 0.3 0.0099 16.3 0.3 1.5 1 0 0 1 1 1 1 Elicitor peptide 1-7 MG4 PF17789.1 KLO10276.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.6 1 1 0 1 1 1 0 Macroglobulin domain MG4 p450 PF00067.22 KLO10278.1 - 5.6e-70 236.4 0.0 1.3e-69 235.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 OPT PF03169.15 KLO10280.1 - 4.3e-189 630.1 63.2 4.9e-189 629.9 63.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BLM_N PF16202.5 KLO10282.1 - 0.038 13.1 3.3 0.055 12.6 3.3 1.1 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein RVP_2 PF08284.11 KLO10284.1 - 1.3e-06 28.2 0.0 1.7e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KLO10284.1 - 0.00046 20.7 0.0 0.00068 20.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KLO10284.1 - 0.00065 20.3 0.0 0.0014 19.2 0.0 1.5 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 KLO10284.1 - 0.0018 18.1 0.1 0.0027 17.5 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 KLO10284.1 - 0.041 13.4 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase Integrase_H2C2 PF17921.1 KLO10285.1 - 4.9e-06 26.5 0.3 4.9e-06 26.5 0.3 1.4 2 0 0 2 2 2 1 Integrase zinc binding domain DUF641 PF04859.12 KLO10286.1 - 0.04 14.3 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) RPN2_C PF18004.1 KLO10286.1 - 0.12 12.3 4.8 0.32 10.9 4.8 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Y_phosphatase3 PF13350.6 KLO10289.1 - 0.097 12.6 0.0 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family GXGXG PF01493.19 KLO10291.1 - 0.09 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 GXGXG motif ADH_zinc_N PF00107.26 KLO10292.1 - 4.2e-18 65.6 0.0 7.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO10292.1 - 3e-09 36.7 0.0 8.5e-09 35.3 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KLO10292.1 - 1.6e-08 35.6 0.0 4.7e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 KLO10292.1 - 0.045 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KLO10292.1 - 0.077 12.4 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HHH_8 PF14716.6 KLO10294.1 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain VID27_PH PF17747.1 KLO10295.1 - 0.072 13.4 0.1 0.098 12.9 0.1 1.4 1 0 0 1 1 1 0 VID27 PH-like domain VIGSSK PF14773.6 KLO10297.1 - 0.46 10.6 1.8 1.7 8.8 0.3 2.5 3 0 0 3 3 3 0 Helicase-associated putative binding domain, C-terminal KilA-N PF04383.13 KLO10302.1 - 0.019 14.8 0.1 0.027 14.3 0.1 1.3 1 1 0 1 1 1 0 KilA-N domain FAR1 PF03101.15 KLO10303.1 - 7.3e-06 26.6 1.3 1.4e-05 25.7 1.3 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain SRP9-21 PF05486.12 KLO10303.1 - 0.034 14.5 0.9 0.058 13.8 0.9 1.4 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) HTH_ABP1_N PF18107.1 KLO10309.1 - 0.077 12.7 0.3 0.16 11.7 0.3 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain SPT6_acidic PF14632.6 KLO10312.1 - 1.9 9.1 9.3 8.6 7.0 1.9 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 adh_short PF00106.25 KLO10314.1 - 1.2e-35 122.7 0.2 1.6e-35 122.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO10314.1 - 1.9e-19 70.2 0.1 3.8e-19 69.2 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO10314.1 - 3.5e-07 30.3 0.4 5.6e-07 29.6 0.4 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KLO10314.1 - 0.08 12.1 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GIT_SHD PF08518.11 KLO10315.1 - 5.8e-22 77.0 1.9 1.4e-11 43.8 1.4 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 KLO10315.1 - 0.013 15.6 3.4 0.015 15.4 0.5 2.6 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Spectrin PF00435.21 KLO10315.1 - 0.016 15.7 15.0 0.3 11.6 3.1 3.8 2 1 0 3 3 3 0 Spectrin repeat TRAF_BIRC3_bd PF16673.5 KLO10315.1 - 0.032 14.0 2.0 0.17 11.7 2.0 2.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Spc7 PF08317.11 KLO10315.1 - 0.12 11.3 27.5 0.11 11.4 12.6 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF3949 PF13133.6 KLO10315.1 - 0.19 12.2 0.1 0.53 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3949) Tweety PF04906.13 KLO10315.1 - 0.33 9.5 2.0 2 7.0 0.1 2.6 2 0 0 2 2 2 0 Tweety BLOC1_2 PF10046.9 KLO10315.1 - 0.45 10.8 11.7 2.5 8.4 2.0 3.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 KLO10315.1 - 0.45 10.5 29.1 0.13 12.3 13.2 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KLO10315.1 - 0.98 8.7 22.3 1.3 8.3 2.8 4.0 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.20 KLO10315.1 - 1.1 8.6 23.4 17 4.7 23.4 2.7 1 1 0 1 1 1 0 Tropomyosin TMPIT PF07851.13 KLO10315.1 - 1.2 8.3 7.8 8.2 5.6 0.1 2.5 2 0 0 2 2 2 0 TMPIT-like protein NPV_P10 PF05531.12 KLO10315.1 - 1.3 9.5 13.8 12 6.5 1.0 5.4 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.8 KLO10315.1 - 1.6 8.8 23.1 0.87 9.7 3.7 3.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KLO10315.1 - 1.9 8.5 13.7 3.1 7.9 1.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 KLO10315.1 - 4 5.9 20.0 7 5.1 19.2 1.7 1 1 0 1 1 1 0 Macoilin family Golgin_A5 PF09787.9 KLO10315.1 - 4.2 6.8 22.9 1.3 8.4 13.3 2.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 TMF_DNA_bd PF12329.8 KLO10315.1 - 4.7 7.3 29.6 0.97 9.5 0.6 4.6 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding LMBR1 PF04791.16 KLO10315.1 - 7.1 5.4 6.9 16 4.2 6.9 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein Noelin-1 PF12308.8 KLO10315.1 - 7.5 6.6 8.7 3.7 7.6 1.8 3.3 2 1 1 3 3 3 0 Neurogenesis glycoprotein AAA PF00004.29 KLO10316.1 - 3.2e-61 205.6 0.0 2.4e-43 147.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KLO10316.1 - 3e-25 88.4 0.2 1.3e-24 86.3 0.3 2.1 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KLO10316.1 - 4.8e-14 51.9 0.0 1.3e-08 34.5 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KLO10316.1 - 8.5e-11 42.5 10.5 0.0013 19.1 2.1 5.3 3 2 1 4 4 3 2 AAA ATPase domain RuvB_N PF05496.12 KLO10316.1 - 1.4e-08 34.6 0.0 0.0016 18.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KLO10316.1 - 1.6e-07 31.9 0.0 0.019 15.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KLO10316.1 - 9.1e-07 28.9 2.8 0.00064 19.7 0.4 3.4 3 1 0 3 3 2 1 NACHT domain AAA_2 PF07724.14 KLO10316.1 - 2.1e-06 28.0 0.0 0.033 14.3 0.0 3.2 3 1 1 4 4 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KLO10316.1 - 2.4e-06 27.0 0.1 0.05 12.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 KLO10316.1 - 2.9e-06 27.3 0.4 0.045 13.8 0.0 3.6 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KLO10316.1 - 4.9e-06 26.8 4.1 0.07 13.4 0.8 4.3 3 2 1 4 4 3 2 AAA domain TsaE PF02367.17 KLO10316.1 - 1.3e-05 25.2 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KLO10316.1 - 3.8e-05 24.0 0.0 0.38 11.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 KLO10316.1 - 0.00011 21.7 0.6 0.83 9.0 0.0 3.3 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 KLO10316.1 - 0.00013 21.2 0.0 0.093 11.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KLO10316.1 - 0.0003 20.6 0.1 0.19 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KLO10316.1 - 0.00032 20.0 0.0 0.32 10.1 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_33 PF13671.6 KLO10316.1 - 0.00032 20.9 0.0 0.022 14.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KLO10316.1 - 0.00032 20.2 0.0 0.04 13.4 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.6 KLO10316.1 - 0.00035 20.6 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KLO10316.1 - 0.00059 19.6 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.9 KLO10316.1 - 0.00079 18.8 0.0 0.41 9.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KLO10316.1 - 0.00081 18.9 0.0 0.21 11.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KLO10316.1 - 0.001 18.8 0.1 0.91 9.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase_2 PF01637.18 KLO10316.1 - 0.0014 18.6 1.2 0.54 10.1 0.0 3.5 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KLO10316.1 - 0.0027 17.3 6.5 0.61 9.6 0.2 4.4 3 2 2 5 5 4 1 AAA domain AAA_3 PF07726.11 KLO10316.1 - 0.0041 17.0 0.0 0.99 9.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KLO10316.1 - 0.0045 16.7 1.6 0.056 13.2 0.1 2.9 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 KLO10316.1 - 0.0047 17.0 0.0 0.7 10.0 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KLO10316.1 - 0.0053 16.5 0.9 0.43 10.3 0.0 3.1 4 0 0 4 4 3 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KLO10316.1 - 0.0063 16.5 0.2 0.28 11.1 0.0 2.3 2 0 0 2 2 2 1 NTPase KTI12 PF08433.10 KLO10316.1 - 0.0071 15.8 1.0 3 7.2 0.1 3.1 3 0 0 3 3 3 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KLO10316.1 - 0.0095 15.2 0.1 1.3 8.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 KLO10316.1 - 0.014 15.7 0.1 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KLO10316.1 - 0.014 15.8 0.0 0.36 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KLO10316.1 - 0.015 14.5 0.1 1.2 8.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KLO10316.1 - 0.019 15.5 0.1 6 7.4 0.0 3.2 3 0 0 3 3 2 0 ABC transporter ATPase PF06745.13 KLO10316.1 - 0.02 14.2 0.7 3.5 6.9 0.0 2.7 2 1 0 2 2 2 0 KaiC Rad17 PF03215.15 KLO10316.1 - 0.026 14.4 0.0 0.8 9.6 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 KLO10316.1 - 0.066 13.0 0.2 1.2 9.0 0.3 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.6 KLO10316.1 - 0.069 13.6 0.3 0.35 11.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KLO10316.1 - 0.087 12.7 0.3 4.5 7.1 0.1 3.1 2 1 1 3 3 3 0 Adenylylsulphate kinase Cytidylate_kin2 PF13189.6 KLO10316.1 - 0.11 12.6 0.2 0.44 10.6 0.0 2.1 3 0 0 3 3 1 0 Cytidylate kinase-like family T2SSE PF00437.20 KLO10316.1 - 0.12 11.4 0.3 1.7 7.6 0.3 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.9 KLO10316.1 - 0.13 12.1 0.3 12 5.6 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF1380 PF07128.12 KLO10316.1 - 0.13 12.5 0.1 0.47 10.6 0.1 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1380) BcrAD_BadFG PF01869.20 KLO10317.1 - 1.6e-11 44.2 0.0 1e-10 41.5 0.0 2.2 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Glyco_transf_49 PF13896.6 KLO10318.1 - 1.7e-63 215.0 0.1 4.9e-52 177.3 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.9 KLO10318.1 - 0.04 13.4 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 CTP_transf_like PF01467.26 KLO10319.1 - 2.2e-20 73.3 0.0 3e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like PhoLip_ATPase_C PF16212.5 KLO10320.1 - 7e-80 268.4 24.8 7e-80 268.4 24.8 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KLO10320.1 - 1.5e-24 85.5 5.3 4.9e-24 83.8 5.3 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KLO10320.1 - 2.1e-13 50.1 0.0 8.5e-13 48.2 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KLO10320.1 - 1.5e-11 45.0 1.0 1.2e-05 25.8 0.3 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KLO10320.1 - 6.5e-09 35.6 0.0 2.1e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KLO10320.1 - 0.0044 16.8 0.1 0.015 15.0 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Abhydrolase_6 PF12697.7 KLO10321.1 - 2.3e-06 28.4 1.2 5.6e-06 27.1 1.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO10321.1 - 0.00015 21.1 0.0 0.00034 20.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KLO10321.1 - 0.0084 16.3 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 KLO10321.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KLO10321.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Cornichon PF03311.14 KLO10322.1 - 2.5e-49 166.6 7.7 2.8e-49 166.5 7.7 1.0 1 0 0 1 1 1 1 Cornichon protein ABC_membrane PF00664.23 KLO10323.1 - 4.2e-53 180.7 3.8 5.8e-53 180.3 3.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KLO10323.1 - 1.3e-31 109.9 0.0 3.1e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KLO10323.1 - 3.2e-06 26.8 0.1 0.0033 16.9 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KLO10323.1 - 0.032 14.3 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 KLO10323.1 - 0.048 13.4 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KLO10323.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KLO10323.1 - 0.076 12.3 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KLO10323.1 - 0.082 13.3 2.7 0.3 11.4 0.6 2.7 2 1 0 2 2 2 0 AAA ATPase domain Transcript_VP30 PF11507.8 KLO10324.1 - 0.068 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 Cornichon PF03311.14 KLO10326.1 - 1.1e-50 171.0 8.0 1.3e-50 170.8 8.0 1.0 1 0 0 1 1 1 1 Cornichon protein Pro_racemase PF05544.11 KLO10327.1 - 9.2e-62 209.0 0.0 2.9e-36 125.1 0.0 2.6 2 1 0 2 2 2 2 Proline racemase An_peroxidase PF03098.15 KLO10329.1 - 3.1e-23 82.2 0.0 9.4e-10 37.7 0.0 4.1 3 1 1 4 4 4 4 Animal haem peroxidase p450 PF00067.22 KLO10329.1 - 0.0016 17.3 0.0 0.0069 15.2 0.0 1.9 3 0 0 3 3 3 1 Cytochrome P450 ABC_membrane PF00664.23 KLO10329.1 - 0.046 13.4 0.4 0.074 12.7 0.4 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region F_bP_aldolase PF01116.20 KLO10330.1 - 1.4e-94 316.7 0.0 1.6e-94 316.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Lipase_GDSL_2 PF13472.6 KLO10330.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Torsin PF06309.11 KLO10330.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Torsin GFA PF04828.14 KLO10331.1 - 1.6e-06 28.4 2.1 1.6e-06 28.4 2.1 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme GFA PF04828.14 KLO10332.1 - 3.2e-07 30.6 0.6 3.2e-07 30.6 0.6 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme F-box-like PF12937.7 KLO10335.1 - 0.00058 19.7 0.0 0.0057 16.5 0.0 2.7 2 1 0 2 2 2 1 F-box-like COX7C PF02935.16 KLO10337.1 - 9.9e-16 57.8 0.4 1.2e-15 57.5 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DUF2273 PF10031.9 KLO10337.1 - 0.11 12.5 0.3 0.16 12.0 0.3 1.2 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Solute_trans_a PF03619.16 KLO10338.1 - 7.3e-89 297.8 12.1 8.7e-89 297.5 12.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.11 KLO10338.1 - 0.0017 18.5 1.8 0.0017 18.5 1.8 2.5 2 1 0 2 2 2 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3332 PF11810.8 KLO10338.1 - 0.16 11.6 0.1 0.26 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) p450 PF00067.22 KLO10339.1 - 1.5e-63 215.2 0.0 1.1e-62 212.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 XPA_C PF05181.12 KLO10343.1 - 0.074 13.0 0.2 0.45 10.5 0.1 2.3 2 0 0 2 2 2 0 XPA protein C-terminus Ribosomal_L37 PF08561.10 KLO10343.1 - 0.11 13.0 0.6 0.11 13.0 0.6 2.6 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L37 DUF1454 PF07305.12 KLO10345.1 - 0.076 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) ubiquitin PF00240.23 KLO10349.1 - 0.00021 21.0 2.7 0.075 12.8 0.0 2.9 3 0 0 3 3 3 2 Ubiquitin family Ubiquitin_2 PF14560.6 KLO10349.1 - 0.018 15.5 0.4 0.1 13.0 0.4 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain Red1 PF07964.11 KLO10349.1 - 0.052 11.8 4.5 0.061 11.6 4.5 1.0 1 0 0 1 1 1 0 Rec10 / Red1 TmoB PF06234.12 KLO10349.1 - 0.21 11.7 2.8 0.73 10.0 0.9 2.3 1 1 1 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) OAD_gamma PF04277.13 KLO10349.1 - 3.9 8.2 6.0 1.6 9.4 1.3 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF5576 PF17739.1 KLO10350.1 - 0.04 14.0 0.2 0.041 14.0 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5576) p450 PF00067.22 KLO10351.1 - 5e-67 226.6 0.0 6e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TFIIB PF00382.19 KLO10354.1 - 4.3e-36 122.8 1.6 1e-17 63.9 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KLO10354.1 - 6.3e-27 93.9 2.9 6.3e-27 93.9 2.9 3.5 4 0 0 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KLO10354.1 - 1.6e-08 33.9 3.5 3.7e-08 32.7 3.5 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KLO10354.1 - 3e-05 23.8 0.8 0.03 14.1 0.3 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain DZR PF12773.7 KLO10354.1 - 0.022 14.8 0.3 0.049 13.7 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RRN7 PF11781.8 KLO10354.1 - 7.2 6.4 8.9 0.15 11.8 2.1 1.8 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Pns11_12 PF17464.2 KLO10354.1 - 8.6 6.0 13.6 2.4 7.8 4.6 2.4 2 0 0 2 2 2 0 Non-structural protein 11 and 12 Solute_trans_a PF03619.16 KLO10355.1 - 1.2e-55 188.9 11.0 1.1e-52 179.2 6.2 2.0 2 0 0 2 2 2 2 Organic solute transporter Ostalpha SelK_SelG PF10961.8 KLO10356.1 - 0.25 12.0 0.2 0.25 12.0 0.2 2.2 2 0 0 2 2 2 0 Selenoprotein SelK_SelG AA_permease_2 PF13520.6 KLO10357.1 - 5.3e-60 203.4 47.9 3e-32 112.0 27.9 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KLO10357.1 - 7.1e-12 44.7 43.0 1.3e-07 30.6 17.0 2.3 1 1 1 2 2 2 2 Amino acid permease Phage_holin_3_6 PF07332.11 KLO10357.1 - 0.35 10.9 0.1 0.35 10.9 0.1 4.1 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III VIT1 PF01988.19 KLO10357.1 - 3.1 7.6 14.5 0.11 12.4 0.2 3.1 3 1 0 3 3 3 0 VIT family AA_permease_2 PF13520.6 KLO10358.1 - 1.1e-75 255.1 55.4 1.3e-75 254.9 55.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KLO10358.1 - 1.2e-14 53.7 45.4 1.8e-14 53.2 45.4 1.1 1 0 0 1 1 1 1 Amino acid permease Bromodomain PF00439.25 KLO10359.1 - 8.6e-23 80.2 0.0 1.7e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain ISG65-75 PF11727.8 KLO10360.1 - 0.29 10.3 0.1 0.35 10.0 0.1 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein Homeodomain PF00046.29 KLO10361.1 - 2.5e-18 65.7 3.7 4.5e-18 64.9 3.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KLO10361.1 - 1.6e-05 24.7 0.3 1.6e-05 24.7 0.3 3.1 4 0 0 4 4 4 1 Homeobox KN domain MRP-L20 PF12824.7 KLO10361.1 - 0.046 13.9 0.9 0.046 13.9 0.9 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 YdaS_antitoxin PF15943.5 KLO10361.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT zf-C3HC4 PF00097.25 KLO10363.1 - 1.8e-10 40.5 8.9 3.2e-10 39.7 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO10363.1 - 2.7e-10 39.9 9.8 4.7e-10 39.1 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO10363.1 - 7.5e-10 39.0 11.2 7.5e-10 39.0 11.2 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KLO10363.1 - 1.7e-08 34.2 5.6 2.6e-08 33.6 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO10363.1 - 9.1e-08 32.0 5.7 1.8e-07 31.0 5.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KLO10363.1 - 1.8e-05 24.6 9.3 2.8e-05 24.0 9.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KLO10363.1 - 2e-05 24.3 6.4 3.9e-05 23.4 6.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KLO10363.1 - 2.7e-05 24.3 9.7 2.7e-05 24.3 9.7 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KLO10363.1 - 6.5e-05 23.0 8.9 0.00013 22.0 8.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF2525 PF10733.9 KLO10363.1 - 0.075 13.3 0.0 6.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2525) DUF2946 PF11162.8 KLO10363.1 - 0.12 13.0 2.7 6.9 7.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) zf-RING_4 PF14570.6 KLO10363.1 - 0.26 11.1 7.1 0.75 9.6 7.1 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KLO10363.1 - 0.37 11.0 4.4 0.67 10.1 4.4 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KLO10363.1 - 0.41 10.7 8.4 0.35 10.9 5.6 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KLO10363.1 - 0.43 10.5 4.4 0.95 9.4 4.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 KLO10363.1 - 1.1 9.0 10.6 2.8 7.8 10.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-P11 PF03854.14 KLO10363.1 - 2 8.1 7.4 5 6.9 7.4 1.6 1 1 0 1 1 1 0 P-11 zinc finger IBR PF01485.21 KLO10363.1 - 7.2 6.9 9.5 15 5.9 7.4 2.4 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Acid_PPase PF12689.7 KLO10364.1 - 4.7e-59 199.0 0.0 5.4e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase RHH_3 PF12651.7 KLO10364.1 - 0.15 12.1 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix domain Sec7_N PF12783.7 KLO10365.1 - 1.4e-49 168.0 0.4 1.4e-49 168.0 0.4 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KLO10365.1 - 4.8e-49 166.4 5.4 4.8e-49 166.4 5.4 2.3 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KLO10365.1 - 9e-39 133.3 1.1 8e-25 87.1 0.3 3.3 2 2 0 2 2 2 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 KLO10365.1 - 2.6e-07 30.4 1.1 0.01 15.7 0.0 4.3 3 0 0 3 3 3 2 Domain of unknown function (DUF1981) BLM10_mid PF16507.5 KLO10365.1 - 0.021 13.5 0.7 0.047 12.3 0.7 1.5 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region DUF1383 PF07134.11 KLO10365.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) CBFD_NFYB_HMF PF00808.23 KLO10366.1 - 4.6e-08 33.2 0.1 7.7e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KLO10366.1 - 0.0023 18.0 0.2 0.0037 17.4 0.2 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TrmB PF01978.19 KLO10366.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2183 PF09949.9 KLO10366.1 - 0.13 12.6 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) BUD22 PF09073.10 KLO10366.1 - 3.1 7.0 20.7 3.5 6.8 20.7 1.1 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 KLO10367.1 - 9.5 6.3 12.4 0.11 12.6 5.0 1.4 2 0 0 2 2 2 0 YL1 nuclear protein FmdA_AmdA PF03069.15 KLO10368.1 - 3.2e-53 180.9 0.5 6.4e-30 104.3 0.3 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family DUF3730 PF12530.8 KLO10368.1 - 0.075 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) DUF3844 PF12955.7 KLO10369.1 - 0.013 15.6 0.4 0.018 15.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) HTH_psq PF05225.16 KLO10372.1 - 0.051 13.3 0.1 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 helix-turn-helix, Psq domain Transposase_21 PF02992.14 KLO10373.1 - 2.6e-07 30.1 0.0 4.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 KLO10373.1 - 1e-06 28.5 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) IMS_HHH PF11798.8 KLO10373.1 - 0.18 12.2 0.0 0.56 10.7 0.0 1.8 2 0 0 2 2 2 0 IMS family HHH motif SNF2_N PF00176.23 KLO10374.1 - 2.4e-59 200.8 0.0 5.6e-58 196.3 0.0 2.7 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO10374.1 - 6e-17 62.0 0.0 5.2e-16 59.0 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO10374.1 - 2.6e-09 37.3 0.0 0.00026 21.0 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KLO10374.1 - 2.1e-05 23.9 0.0 6.7e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DNA_mis_repair PF01119.19 KLO10375.1 - 4.3e-18 65.1 0.0 1.1e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KLO10375.1 - 2.9e-11 43.3 0.1 5.2e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KLO10375.1 - 2.1e-07 31.5 0.0 4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Microvir_H PF04687.12 KLO10375.1 - 0.039 13.3 0.3 0.067 12.6 0.3 1.3 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) MutL_C PF08676.11 KLO10376.1 - 1.7e-21 76.5 0.4 4.4e-21 75.2 0.4 1.7 1 1 0 1 1 1 1 MutL C terminal dimerisation domain F-box-like PF12937.7 KLO10377.1 - 0.0004 20.2 2.3 0.00069 19.5 1.0 2.1 2 0 0 2 2 2 1 F-box-like Rhodanese PF00581.20 KLO10378.1 - 3.2e-08 34.1 0.0 4.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Tcp11 PF05794.13 KLO10382.1 - 1.2e-25 90.5 5.8 1.2e-24 87.2 5.8 2.4 1 1 0 1 1 1 1 T-complex protein 11 Prenyltrans PF00432.21 KLO10383.1 - 2.2e-57 190.5 2.9 6.6e-11 41.8 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KLO10383.1 - 9.4e-05 21.7 0.0 0.00048 19.3 0.0 1.8 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain Peptidase_M20 PF01546.28 KLO10383.1 - 0.027 14.2 0.2 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 2OG-FeII_Oxy_2 PF13532.6 KLO10385.1 - 3.5e-30 105.7 0.0 4.2e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_1 PF00515.28 KLO10386.1 - 2.5e-38 128.3 13.9 2.3e-06 27.2 0.0 10.8 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 KLO10386.1 - 2.4e-37 124.0 13.9 0.00017 21.4 0.1 11.1 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.6 KLO10386.1 - 3e-25 87.6 5.2 7.4e-06 25.5 0.1 7.7 4 2 3 7 7 7 5 TPR repeat TPR_16 PF13432.6 KLO10386.1 - 1.3e-24 86.6 14.9 2.6e-07 31.1 0.0 8.0 6 3 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KLO10386.1 - 1.8e-24 83.9 17.6 0.00048 20.1 0.1 10.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 KLO10386.1 - 3.1e-20 71.0 2.3 0.094 13.1 0.0 8.0 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KLO10386.1 - 1.5e-18 67.0 11.1 4.4e-05 23.9 2.5 6.0 4 2 1 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KLO10386.1 - 5e-18 64.3 13.1 0.00012 22.6 0.0 9.1 4 2 5 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KLO10386.1 - 6.8e-17 61.5 17.0 0.0037 17.5 0.2 8.3 3 1 3 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 KLO10386.1 - 1.9e-15 56.8 7.2 0.0087 16.2 0.1 5.6 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KLO10386.1 - 8e-15 53.7 6.2 0.01 15.8 0.1 9.1 8 1 1 9 9 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO10386.1 - 4.7e-13 49.2 3.2 0.041 14.1 0.2 4.5 3 1 0 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KLO10386.1 - 8.2e-09 35.3 0.8 9.8e-05 21.9 0.7 3.7 2 1 1 3 3 3 2 MalT-like TPR region TPR_6 PF13174.6 KLO10386.1 - 3.3e-08 33.6 20.9 0.099 13.3 0.0 8.6 10 0 0 10 10 8 2 Tetratricopeptide repeat DUF3856 PF12968.7 KLO10386.1 - 2e-06 27.9 1.4 0.85 9.7 0.1 5.3 4 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.9 KLO10386.1 - 5.2e-06 25.8 5.1 0.33 10.4 0.0 5.9 6 0 0 6 6 6 2 SHNi-TPR Rapsyn_N PF10579.9 KLO10386.1 - 8.7e-05 22.5 0.1 0.63 10.2 0.0 4.0 4 0 0 4 4 4 1 Rapsyn N-terminal myristoylation and linker region TPR_20 PF14561.6 KLO10386.1 - 0.00025 21.3 17.8 0.077 13.3 1.3 5.6 5 2 3 8 8 5 2 Tetratricopeptide repeat MAS20 PF02064.15 KLO10386.1 - 0.00025 21.1 4.7 0.039 14.0 0.3 4.1 3 1 1 4 4 4 1 MAS20 protein import receptor TPR_15 PF13429.6 KLO10386.1 - 0.00034 19.9 6.4 0.33 10.1 0.6 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat Coatomer_E PF04733.14 KLO10386.1 - 0.0011 18.5 0.9 0.49 9.8 0.1 3.0 3 0 0 3 3 3 1 Coatomer epsilon subunit TPR_10 PF13374.6 KLO10386.1 - 0.0022 17.8 17.8 0.97 9.4 0.2 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat RPN7 PF10602.9 KLO10386.1 - 0.0032 17.2 5.0 1.5 8.5 0.2 3.7 2 1 1 3 3 3 1 26S proteasome subunit RPN7 TPR_21 PF09976.9 KLO10386.1 - 0.0097 15.6 17.5 1.6 8.4 0.6 5.4 4 2 2 6 6 5 2 Tetratricopeptide repeat-like domain CwsA PF10814.8 KLO10386.1 - 0.024 14.8 0.2 0.091 12.9 0.2 2.0 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA TPR_4 PF07721.14 KLO10386.1 - 0.046 14.3 0.2 2.6 8.9 0.0 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat PPR_2 PF13041.6 KLO10386.1 - 0.083 13.1 0.6 45 4.4 0.0 4.1 4 0 0 4 4 3 0 PPR repeat family Reovirus_cap PF00979.17 KLO10386.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 BTAD PF03704.17 KLO10386.1 - 0.21 12.0 8.0 1.5 9.2 0.0 4.4 4 1 2 6 6 4 0 Bacterial transcriptional activator domain ANAPC5 PF12862.7 KLO10386.1 - 0.29 11.2 10.5 0.3 11.2 0.4 4.2 5 2 0 5 5 3 0 Anaphase-promoting complex subunit 5 PPR PF01535.20 KLO10386.1 - 1 9.8 2.8 69 4.0 0.0 4.4 5 0 0 5 5 3 0 PPR repeat DUF932 PF06067.11 KLO10386.1 - 1.2 8.9 3.6 1.4 8.7 0.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF932) MIT PF04212.18 KLO10386.1 - 1.3 9.2 12.5 5.8 7.1 0.0 6.3 6 2 1 7 7 7 0 MIT (microtubule interacting and transport) domain Rad60-SLD PF11976.8 KLO10387.1 - 2.9e-10 39.8 4.2 7.4e-08 32.1 0.6 2.4 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KLO10387.1 - 4.3e-09 36.0 1.6 1.1e-06 28.3 0.1 2.1 1 1 1 2 2 2 2 Ubiquitin family tRNA-synt_1g PF09334.11 KLO10387.1 - 0.063 12.0 0.4 0.071 11.8 0.4 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (M) ATG22 PF11700.8 KLO10388.1 - 7.1e-145 483.3 11.7 8.3e-145 483.1 11.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KLO10388.1 - 6.7e-06 25.3 51.2 0.001 18.1 23.7 3.6 2 2 1 3 3 3 3 Major Facilitator Superfamily DUF4050 PF13259.6 KLO10388.1 - 0.14 12.5 0.1 0.21 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF4451 PF14616.6 KLO10389.1 - 8.3e-30 103.5 1.8 1e-29 103.2 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) FpoO PF10621.9 KLO10389.1 - 0.035 14.4 0.1 1.3 9.3 0.1 2.1 2 0 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO Rubredoxin_2 PF18073.1 KLO10389.1 - 0.11 12.3 0.2 0.11 12.3 0.2 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain IGFBP PF00219.18 KLO10389.1 - 0.26 12.0 3.2 8.3 7.1 0.6 2.4 2 0 0 2 2 2 0 Insulin-like growth factor binding protein EMP24_GP25L PF01105.24 KLO10390.1 - 8.7e-41 139.9 0.0 1e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Herpes_UL49_5 PF05702.11 KLO10390.1 - 0.023 14.8 0.1 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein 2-Hacid_dh_C PF02826.19 KLO10391.1 - 6.3e-56 188.5 0.0 9.3e-56 188.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KLO10391.1 - 5.7e-31 107.0 0.0 8.9e-31 106.3 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KLO10391.1 - 0.00022 21.4 0.0 0.00045 20.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KLO10391.1 - 0.01 15.4 0.0 0.029 14.0 0.0 1.8 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain CHASE2 PF05226.11 KLO10391.1 - 0.05 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 CHASE2 domain PP2C PF00481.21 KLO10392.1 - 4.4e-08 33.1 0.0 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KLO10392.1 - 1.4e-05 25.1 0.0 4.6e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KLO10392.1 - 6.4e-05 22.7 0.0 0.00042 20.0 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C zf-MYND PF01753.18 KLO10393.1 - 8.5e-11 41.8 7.5 2.4e-10 40.3 7.5 1.8 1 0 0 1 1 1 1 MYND finger AAA-ATPase_like PF09820.9 KLO10393.1 - 0.068 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Predicted AAA-ATPase zf-C6H2 PF15801.5 KLO10393.1 - 0.11 12.9 4.4 0.28 11.5 4.4 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding SurE PF01975.17 KLO10394.1 - 5.5e-32 111.1 0.1 7.9e-32 110.6 0.1 1.2 1 0 0 1 1 1 1 Survival protein SurE Pkinase PF00069.25 KLO10395.1 - 2.4e-66 223.8 0.0 2.3e-65 220.6 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO10395.1 - 6.4e-31 107.6 0.0 8.4e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO10395.1 - 0.0026 17.1 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like MAT1 PF06391.13 KLO10396.1 - 2.4e-53 181.0 13.8 3.1e-53 180.6 13.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KLO10396.1 - 3.8e-22 77.9 7.4 6.2e-22 77.2 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO10396.1 - 8.2e-06 25.6 6.8 1.8e-05 24.5 6.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO10396.1 - 2.1e-05 24.4 7.4 0.00013 21.9 7.8 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KLO10396.1 - 4.1e-05 23.8 6.7 6.5e-05 23.2 6.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KLO10396.1 - 5e-05 23.0 7.2 9.8e-05 22.1 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO10396.1 - 0.00012 21.9 6.1 0.00035 20.4 6.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO10396.1 - 0.0032 17.4 6.4 0.0082 16.1 2.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 KLO10396.1 - 0.0045 16.7 2.9 0.18 11.6 1.4 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KLO10396.1 - 0.011 16.0 2.5 0.021 15.1 2.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KLO10396.1 - 0.018 14.9 9.4 0.33 10.9 9.7 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KLO10396.1 - 2.6 8.3 7.4 20 5.4 8.0 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Lactonase PF10282.9 KLO10397.1 - 7e-41 140.6 0.0 8.5e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Misat_Tub_SegII PF10644.9 KLO10397.1 - 0.047 14.0 0.1 0.074 13.4 0.1 1.3 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain LigB PF02900.18 KLO10398.1 - 6.4e-37 127.1 0.0 7.6e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF4910 PF16254.5 KLO10398.1 - 0.054 12.4 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) Peroxidase_ext PF11895.8 KLO10399.1 - 5.3e-19 67.9 0.3 9.9e-19 67.1 0.3 1.4 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 KLO10399.1 - 2.7e-14 53.4 0.0 1.1e-11 44.9 0.0 2.2 2 0 0 2 2 2 2 Peroxidase Peroxidase_ext PF11895.8 KLO10400.1 - 2.1e-25 88.4 3.1 4.3e-25 87.4 3.1 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 KLO10400.1 - 3e-23 82.7 0.0 4.9e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Peroxidase EF-hand_4 PF12763.7 KLO10402.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand APG9 PF04109.16 KLO10403.1 - 8.8e-200 664.8 9.4 1e-199 664.5 9.4 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 NAD_binding_7 PF13241.6 KLO10404.1 - 2.1e-29 102.0 0.0 4.5e-29 101.0 0.0 1.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KLO10404.1 - 1.9e-24 85.1 0.1 3.2e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KLO10404.1 - 8.6e-13 47.5 0.1 1.6e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.21 KLO10404.1 - 0.046 13.1 1.2 0.098 12.0 0.0 1.9 2 0 0 2 2 2 0 ThiF family ICEA PF05315.11 KLO10404.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 ICEA Protein DUF2420 PF10336.9 KLO10405.1 - 5e-10 39.4 0.2 1.9e-09 37.5 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2420) HTH_9 PF08221.11 KLO10406.1 - 2.7e-20 72.2 0.9 1.1e-13 51.1 1.3 3.7 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 KLO10406.1 - 2.8e-14 53.5 0.4 1.4e-12 47.9 0.6 2.5 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 KLO10406.1 - 1.7e-13 50.3 0.3 3.1e-09 36.6 0.0 4.2 4 0 0 4 4 4 2 TFIIE alpha subunit Metallophos PF00149.28 KLO10407.1 - 7.4e-13 49.5 0.2 1.2e-12 48.8 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KLO10407.1 - 1.9e-06 28.2 0.1 6.5e-05 23.2 0.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SPT16 PF08644.11 KLO10408.1 - 9.5e-58 194.7 0.2 9.5e-58 194.7 0.2 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KLO10408.1 - 4.3e-38 130.6 2.0 6.6e-38 130.0 0.0 2.5 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KLO10408.1 - 2.7e-22 79.5 0.0 5e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KLO10408.1 - 2.4e-14 53.5 0.3 8.6e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 KLO10408.1 - 0.008 16.4 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3956) TPR_MalT PF17874.1 KLO10409.1 - 0.033 13.6 0.3 0.046 13.1 0.3 1.2 1 0 0 1 1 1 0 MalT-like TPR region Abhydrolase_1 PF00561.20 KLO10411.1 - 2.2e-19 70.1 0.0 5e-19 69.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO10411.1 - 6.5e-17 62.9 0.0 7.8e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO10411.1 - 2.4e-14 53.2 0.0 3.8e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KLO10411.1 - 0.00022 21.3 0.0 0.00056 20.0 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.13 KLO10411.1 - 0.00066 19.6 0.1 0.0055 16.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KLO10411.1 - 0.0015 18.5 0.2 0.36 10.7 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 KLO10411.1 - 0.014 15.5 0.0 0.037 14.1 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 KLO10411.1 - 0.016 14.7 0.0 5.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KLO10411.1 - 0.024 14.1 0.3 0.67 9.4 0.1 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family LIDHydrolase PF10230.9 KLO10411.1 - 0.032 13.8 0.0 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 KLO10411.1 - 0.072 12.7 0.0 0.2 11.3 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) UPF0227 PF05728.12 KLO10411.1 - 0.091 12.7 0.0 0.65 9.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Esterase PF00756.20 KLO10411.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Putative esterase DEAD PF00270.29 KLO10412.1 - 4.4e-21 75.4 0.0 1.1e-20 74.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KLO10412.1 - 2.9e-14 53.6 1.0 9.1e-14 52.0 1.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KLO10412.1 - 9e-14 51.8 0.2 1.5e-11 44.6 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO10412.1 - 8.4e-07 29.2 0.0 2.9e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KLO10412.1 - 2.8e-06 27.7 0.0 5.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like FHIPEP PF00771.20 KLO10412.1 - 0.018 13.5 0.2 0.026 13.0 0.2 1.1 1 0 0 1 1 1 0 FHIPEP family Pkinase PF00069.25 KLO10413.1 - 2.2e-23 83.0 0.0 3.3e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO10413.1 - 1.2e-13 50.9 0.0 4.6e-13 49.0 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase TMEM100 PF16311.5 KLO10415.1 - 0.01 15.5 0.2 0.012 15.2 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 100 HSP20 PF00011.21 KLO10417.1 - 0.00025 21.2 0.0 0.0005 20.2 0.0 1.6 1 1 0 1 1 1 1 Hsp20/alpha crystallin family PixA PF12306.8 KLO10417.1 - 0.0079 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Inclusion body protein NAD_binding_2 PF03446.15 KLO10418.1 - 2e-30 106.0 0.0 2.8e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KLO10418.1 - 3.2e-30 104.9 0.0 6.1e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Epimerase PF01370.21 KLO10419.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cytochrom_B561 PF03188.16 KLO10420.1 - 3.1e-09 37.1 5.9 3.7e-09 36.8 4.7 1.8 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 IncD PF17628.2 KLO10420.1 - 0.93 9.3 2.7 3.7 7.3 0.4 2.1 2 0 0 2 2 2 0 Inclusion membrane protein D Sec7 PF01369.20 KLO10421.1 - 1.8e-67 226.6 0.0 3.3e-67 225.7 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KLO10421.1 - 3e-21 76.0 0.7 4.3e-20 72.2 0.0 3.4 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KLO10421.1 - 0.004 17.0 1.5 0.41 10.5 0.1 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Proteasome PF00227.26 KLO10422.1 - 9.9e-60 201.3 0.0 1.4e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KLO10422.1 - 5.6e-15 54.7 0.1 1.6e-14 53.2 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_C78 PF07910.13 KLO10423.1 - 1.5e-42 145.4 0.0 4.2e-42 144.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family C78 Pyrophosphatase PF00719.19 KLO10423.1 - 0.053 13.3 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Inorganic pyrophosphatase GreA_GreB PF01272.19 KLO10423.1 - 0.13 12.2 2.4 1.2 9.1 1.0 2.5 2 0 0 2 2 2 0 Transcription elongation factor, GreA/GreB, C-term zf-U1 PF06220.12 KLO10423.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 U1 zinc finger Aminotran_1_2 PF00155.21 KLO10424.1 - 2.3e-16 59.9 0.0 3.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase PF00069.25 KLO10425.1 - 6.6e-46 156.8 0.0 1.2e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO10425.1 - 8.7e-45 153.0 0.0 1.2e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.27 KLO10425.1 - 0.0089 15.8 0.4 0.029 14.1 0.4 2.0 1 0 0 1 1 1 1 SAP domain APH PF01636.23 KLO10425.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KLO10425.1 - 0.041 12.8 0.0 0.087 11.8 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KLO10425.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 AAA PF00004.29 KLO10427.1 - 1e-11 45.4 0.0 2.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KLO10427.1 - 1.2e-06 28.6 0.0 0.00069 19.6 0.0 2.5 2 1 0 2 2 2 2 Rad17 P-loop domain AAA_16 PF13191.6 KLO10427.1 - 0.00011 22.6 0.0 0.0033 17.8 0.0 2.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KLO10427.1 - 0.00014 21.9 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KLO10427.1 - 0.0029 17.9 0.0 0.0069 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 KLO10427.1 - 0.0076 16.0 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KLO10427.1 - 0.019 15.2 0.0 0.22 11.8 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KLO10427.1 - 0.061 12.9 0.2 2.2 7.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KLO10427.1 - 0.097 13.2 0.3 1.7 9.2 0.0 3.1 4 1 1 5 5 5 0 AAA domain TsaE PF02367.17 KLO10427.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MFS_1 PF07690.16 KLO10428.1 - 1.7e-22 79.9 34.2 2.2e-22 79.5 33.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KLO10428.1 - 0.00032 20.1 6.9 0.00032 20.1 6.9 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CLP1_P PF16575.5 KLO10429.1 - 1e-36 126.5 0.0 1.9e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KLO10429.1 - 2.6e-32 110.9 0.0 4.3e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KLO10429.1 - 1.1e-25 90.3 0.0 1.8e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 KLO10429.1 - 0.045 13.5 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KLO10429.1 - 0.21 11.3 0.0 0.42 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KLO10429.1 - 0.22 11.0 0.0 0.4 10.1 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Pyr_redox_2 PF07992.14 KLO10430.1 - 2e-40 138.9 0.0 2.8e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO10430.1 - 1.8e-11 44.4 0.2 9.4e-08 32.5 0.0 3.4 4 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 KLO10430.1 - 2e-10 41.0 5.9 1.4e-07 31.9 1.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KLO10430.1 - 4.6e-10 38.3 0.8 0.00033 20.0 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KLO10430.1 - 6.6e-08 31.9 0.8 0.003 17.3 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KLO10430.1 - 1.9e-06 27.1 4.0 0.00035 19.9 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KLO10430.1 - 0.0004 20.2 0.1 0.71 9.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.6 KLO10430.1 - 0.0041 16.4 3.2 0.19 10.9 2.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KLO10430.1 - 0.02 15.3 0.0 0.14 12.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Syntaxin-6_N PF09177.11 KLO10430.1 - 0.092 13.3 0.1 0.26 11.8 0.1 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal SPARC_Ca_bdg PF10591.9 KLO10430.1 - 0.096 13.0 0.2 18 5.7 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KLO10430.1 - 0.47 10.4 1.9 22 5.0 0.2 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand ATP-synt_ab PF00006.25 KLO10431.1 - 6.7e-63 212.2 0.0 1.2e-62 211.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KLO10431.1 - 1.5e-21 76.6 1.2 4.3e-21 75.2 1.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KLO10431.1 - 0.0057 15.9 0.8 0.012 14.9 0.1 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 KLO10431.1 - 0.022 15.2 0.0 0.4 11.1 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KLO10431.1 - 0.029 14.3 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KLO10431.1 - 0.033 14.1 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KLO10431.1 - 0.051 13.9 0.2 0.16 12.4 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 KLO10431.1 - 0.077 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 KLO10431.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KLO10431.1 - 0.1 13.0 0.6 0.31 11.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain T3SS_ATPase_C PF18269.1 KLO10431.1 - 0.22 11.4 0.7 0.99 9.3 0.7 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain CPDase PF07823.11 KLO10432.1 - 2e-17 63.6 0.2 3.7e-16 59.4 0.2 2.6 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KLO10432.1 - 7.7e-05 22.6 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KLO10432.1 - 0.0015 18.7 0.1 0.0075 16.4 0.0 1.9 2 0 0 2 2 2 1 LigT like Phosphoesterase CPDase PF07823.11 KLO10433.1 - 0.00014 21.6 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein Histone PF00125.24 KLO10434.1 - 1.5e-49 167.7 2.7 1.7e-49 167.5 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KLO10434.1 - 2.6e-05 24.5 0.1 4.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KLO10434.1 - 7.2e-05 22.9 1.0 0.00011 22.3 0.1 1.7 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KLO10434.1 - 0.00057 20.1 0.5 0.0014 18.9 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KLO10434.1 - 0.0026 18.4 1.9 0.0033 18.0 1.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 KLO10434.1 - 0.086 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KLO10434.1 - 0.092 12.8 0.2 0.16 12.0 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Pkinase PF00069.25 KLO10435.1 - 3e-73 246.5 0.0 3.9e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO10435.1 - 5.5e-40 137.3 0.0 7.9e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KLO10435.1 - 1.5e-16 60.9 0.1 6.1e-10 39.6 0.0 3.5 3 0 0 3 3 3 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KLO10435.1 - 4.4e-13 49.1 0.1 1.3e-12 47.6 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KLO10435.1 - 1.2e-06 28.0 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO10435.1 - 0.00027 20.6 0.1 0.00048 19.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KLO10435.1 - 0.00066 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KLO10435.1 - 0.027 13.8 0.1 0.11 11.8 0.1 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO10435.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family YukC PF10140.9 KLO10435.1 - 0.09 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Macoilin PF09726.9 KLO10435.1 - 1.1 7.7 3.2 1.5 7.2 3.2 1.1 1 0 0 1 1 1 0 Macoilin family PMT_4TMC PF16192.5 KLO10436.1 - 0.17 11.5 6.0 4.6 6.8 0.1 2.3 2 0 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase An_peroxidase PF03098.15 KLO10438.1 - 1.5e-36 126.1 0.0 1e-22 80.5 0.0 3.4 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 KLO10438.1 - 0.00035 19.4 0.0 0.0052 15.6 0.0 2.4 1 1 1 2 2 2 1 Cytochrome P450 VirionAssem_T7 PF11653.8 KLO10438.1 - 0.22 12.1 2.8 6.3 7.4 0.4 2.5 1 1 1 2 2 2 0 Bacteriophage T7 virion assembly protein Acetyltransf_1 PF00583.25 KLO10444.1 - 8.6e-11 42.1 0.0 1.7e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KLO10444.1 - 1.6e-07 31.2 0.0 3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KLO10444.1 - 7.1e-07 29.2 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KLO10444.1 - 3e-06 27.3 0.0 6.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO10444.1 - 6.8e-06 26.4 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KLO10444.1 - 6.5e-05 23.6 0.0 0.00015 22.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KLO10444.1 - 0.0008 19.5 0.1 0.0015 18.6 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 KLO10444.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Asp PF00026.23 KLO10446.1 - 8.2e-46 156.9 8.8 1.1e-45 156.5 8.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO10446.1 - 2.4e-09 37.7 5.4 3.1e-06 27.5 0.1 3.1 1 1 2 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KLO10446.1 - 0.0011 19.6 2.9 0.042 14.5 0.3 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KLO10446.1 - 0.022 15.3 1.7 0.25 11.9 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease BaffR-Tall_bind PF09256.10 KLO10450.1 - 0.068 12.9 0.9 0.15 11.8 0.9 1.6 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding Asp PF00026.23 KLO10453.1 - 4.1e-49 167.7 5.6 8.2e-49 166.7 5.6 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO10453.1 - 6.5e-11 42.8 2.0 7.9e-06 26.2 0.2 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KLO10453.1 - 2.1e-07 31.5 1.7 0.00015 22.3 0.2 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KLO10453.1 - 0.00027 21.4 1.6 0.049 14.2 0.1 2.8 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Arrestin_C PF02752.22 KLO10454.1 - 5.9e-07 30.0 0.0 2e-06 28.3 0.0 1.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain STAG PF08514.11 KLO10454.1 - 0.2 11.6 0.1 0.43 10.5 0.1 1.5 1 0 0 1 1 1 0 STAG domain DUF5127 PF17168.4 KLO10456.1 - 6.7e-56 189.6 3.8 6.7e-56 189.6 3.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO10456.1 - 6.2e-47 159.5 0.8 1.5e-46 158.2 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO10456.1 - 6.8e-37 127.5 0.0 1.4e-36 126.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO10456.1 - 2.2e-06 27.1 0.5 5.9e-06 25.7 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) DUF5127 PF17168.4 KLO10459.1 - 2e-59 201.2 1.9 3.4e-59 200.4 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO10459.1 - 7.2e-49 165.8 0.2 1.6e-48 164.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO10459.1 - 4.6e-44 150.8 0.0 1.1e-43 149.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO10459.1 - 0.017 14.7 0.2 0.037 13.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) PhageMin_Tail PF10145.9 KLO10459.1 - 0.045 13.6 1.0 0.11 12.4 1.0 1.6 1 0 0 1 1 1 0 Phage-related minor tail protein Bac_rhamnosid6H PF17389.2 KLO10459.1 - 0.072 12.3 0.1 0.33 10.2 0.1 2.0 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF4965 PF16335.5 KLO10460.1 - 2.2e-48 164.2 0.9 3.6e-48 163.5 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO10460.1 - 3.9e-41 141.3 0.0 7.2e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 KLO10460.1 - 7.6e-31 107.7 1.9 1.4e-29 103.5 0.8 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KLO10460.1 - 9.8e-06 25.0 0.2 2.2e-05 23.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KLO10460.1 - 0.053 12.8 0.3 0.22 10.7 0.3 1.8 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF5127 PF17168.4 KLO10461.1 - 1.7e-39 135.9 2.6 2.2e-39 135.6 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KLO10461.1 - 0.0001 21.8 0.1 0.00026 20.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Fanconi_C PF02106.15 KLO10461.1 - 0.082 11.6 0.2 0.11 11.1 0.2 1.1 1 0 0 1 1 1 0 Fanconi anaemia group C protein GalBD_like PF17974.1 KLO10461.1 - 0.12 12.5 0.1 0.18 12.0 0.1 1.2 1 0 0 1 1 1 0 Galactose-binding domain-like AAA_22 PF13401.6 KLO10462.1 - 6.8e-07 29.6 0.0 3.4e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KLO10462.1 - 2.7e-06 27.4 0.0 4.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO10462.1 - 1.2e-05 25.8 0.1 0.00011 22.7 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KLO10462.1 - 0.016 15.2 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KLO10462.1 - 0.019 15.3 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PPV_E1_C PF00519.17 KLO10462.1 - 0.026 13.4 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase NB-ARC PF00931.22 KLO10462.1 - 0.027 13.7 0.0 0.061 12.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 KLO10462.1 - 0.053 13.1 0.0 0.15 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KLO10462.1 - 0.098 13.1 0.0 0.63 10.5 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 KLO10462.1 - 0.15 11.9 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 KLO10462.1 - 0.18 11.1 0.0 0.42 9.9 0.0 1.5 1 0 0 1 1 1 0 KaiC Methyltransf_FA PF12248.8 KLO10463.1 - 0.0061 16.9 0.1 0.012 15.9 0.1 1.4 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase DUF4150 PF13665.6 KLO10464.1 - 0.09 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) AAA_22 PF13401.6 KLO10466.1 - 0.0096 16.2 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KLO10466.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KLO10466.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KLO10467.1 - 8.9e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KLO10467.1 - 0.0004 20.7 0.0 0.0018 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO10467.1 - 0.0038 17.6 0.0 0.013 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Helo_like_N PF17111.5 KLO10467.1 - 0.024 14.0 0.1 0.099 12.0 0.0 2.0 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins NB-ARC PF00931.22 KLO10467.1 - 0.064 12.4 0.0 0.3 10.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain PPV_E1_C PF00519.17 KLO10467.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase zf-RVT PF13966.6 KLO10469.1 - 0.0033 18.1 0.2 0.0061 17.2 0.2 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase NACHT PF05729.12 KLO10470.1 - 9.2e-10 38.7 0.0 2.2e-06 27.7 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 KLO10470.1 - 6.6e-07 29.7 0.0 6.5e-05 23.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO10470.1 - 4.2e-06 27.2 0.0 0.0071 16.7 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 KLO10470.1 - 0.00083 19.8 0.1 0.14 12.6 0.0 3.9 4 2 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KLO10470.1 - 0.0018 18.3 0.0 0.72 9.7 0.0 3.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea APS_kinase PF01583.20 KLO10470.1 - 0.0091 15.9 1.1 0.77 9.6 0.1 2.7 3 0 0 3 3 3 1 Adenylylsulphate kinase ATP-synt PF00231.19 KLO10470.1 - 0.045 13.5 0.2 0.12 12.1 0.2 1.7 1 0 0 1 1 1 0 ATP synthase NB-ARC PF00931.22 KLO10470.1 - 0.051 12.8 0.0 1.6 7.8 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain DUF4974 PF16344.5 KLO10470.1 - 0.16 12.0 1.4 0.8 9.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) NACHT PF05729.12 KLO10473.1 - 2e-13 50.6 0.1 1.6e-05 24.9 0.0 3.0 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO10473.1 - 9.8e-09 35.8 0.0 0.0016 18.8 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KLO10473.1 - 3e-07 30.8 0.0 0.0043 17.3 0.0 3.2 2 0 0 2 2 2 2 AAA domain KAP_NTPase PF07693.14 KLO10473.1 - 2.6e-06 26.9 0.8 0.0021 17.3 0.0 3.4 3 0 0 3 3 3 1 KAP family P-loop domain AAA PF00004.29 KLO10473.1 - 0.0002 21.8 0.0 0.18 12.2 0.0 3.4 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KLO10473.1 - 0.0016 17.7 0.0 0.4 9.8 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain RNA_helicase PF00910.22 KLO10473.1 - 0.0035 17.7 0.0 1.2 9.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 KLO10473.1 - 0.0096 15.9 0.0 1.4 8.7 0.0 3.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KLO10473.1 - 0.0096 16.3 0.0 11 6.4 0.1 3.3 2 1 0 2 2 2 1 AAA domain ATP-synt PF00231.19 KLO10473.1 - 0.043 13.5 0.1 0.081 12.6 0.1 1.4 1 0 0 1 1 1 0 ATP synthase APS_kinase PF01583.20 KLO10473.1 - 0.093 12.6 0.9 20 5.1 0.0 3.0 3 0 0 3 3 3 0 Adenylylsulphate kinase T2SSE PF00437.20 KLO10473.1 - 0.15 11.1 0.0 18 4.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 KLO10476.1 - 2.2e-07 30.9 0.0 3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO10476.1 - 9.6e-07 29.3 0.0 1.3e-06 28.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO10476.1 - 6.1e-05 23.3 0.0 8.6e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KLO10476.1 - 8.6e-05 22.6 0.0 0.0001 22.3 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KLO10476.1 - 0.0015 18.7 0.0 0.0026 17.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KLO10476.1 - 0.0031 16.7 0.0 0.0033 16.7 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain ResIII PF04851.15 KLO10476.1 - 0.011 15.7 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KLO10476.1 - 0.019 14.3 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 KLO10476.1 - 0.021 14.9 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KLO10476.1 - 0.032 14.6 0.0 0.048 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 KLO10476.1 - 0.16 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 KLO10479.1 - 2.1e-05 24.5 0.0 5.4e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KLO10479.1 - 0.00011 22.4 0.0 0.00058 20.1 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO10479.1 - 0.00054 20.4 0.1 0.0015 19.0 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KLO10479.1 - 0.002 18.5 0.0 0.0076 16.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KLO10479.1 - 0.035 13.7 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KLO10479.1 - 0.036 13.3 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 KLO10479.1 - 0.066 13.8 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KLO10479.1 - 0.12 11.5 0.0 0.27 10.4 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KLO10480.1 - 1.1e-05 25.4 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO10480.1 - 2.3e-05 24.8 0.0 7.8e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KLO10480.1 - 2.8e-05 24.1 0.0 3.7e-05 23.8 0.0 1.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KLO10480.1 - 0.00012 22.3 0.0 0.00041 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KLO10480.1 - 0.0057 15.9 0.0 0.0064 15.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain ResIII PF04851.15 KLO10480.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KLO10480.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase F-box-like PF12937.7 KLO10485.1 - 0.0025 17.7 2.6 0.0061 16.4 0.9 2.6 2 1 0 2 2 2 1 F-box-like CAP PF00188.26 KLO10487.1 - 1.3e-22 81.0 6.4 1.6e-22 80.6 6.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MFS_1 PF07690.16 KLO10488.1 - 8.7e-28 97.3 46.0 1.9e-24 86.3 35.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.18 KLO10488.1 - 0.001 17.9 4.8 0.0027 16.5 4.7 1.7 2 0 0 2 2 2 1 Reduced folate carrier MFS_4 PF06779.14 KLO10488.1 - 0.096 12.0 28.1 0.72 9.1 28.1 2.0 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB F-box-like PF12937.7 KLO10489.1 - 3e-08 33.4 0.6 1.9e-07 30.9 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO10489.1 - 7 6.7 6.6 13 5.8 0.1 3.2 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO10490.1 - 5.5e-10 39.0 0.9 1.1e-09 38.0 0.2 2.0 2 0 0 2 2 2 1 F-box-like TPR_1 PF00515.28 KLO10490.1 - 1.1e-07 31.3 0.0 0.0079 16.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO10490.1 - 3.5e-07 29.8 0.0 0.37 11.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KLO10490.1 - 4.1e-05 24.0 0.1 0.84 10.6 0.0 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat LRR_4 PF12799.7 KLO10490.1 - 0.0012 19.2 1.6 21 5.7 0.0 4.8 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) TPR_19 PF14559.6 KLO10490.1 - 0.0015 19.0 0.1 0.2 12.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.10 KLO10490.1 - 0.0033 16.5 0.1 0.0064 15.5 0.0 1.4 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 KLO10490.1 - 0.045 13.9 0.0 0.29 11.3 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KLO10490.1 - 0.061 13.6 0.1 8.2 6.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box PF00646.33 KLO10490.1 - 0.065 13.1 0.7 0.46 10.4 0.7 2.5 1 1 0 1 1 1 0 F-box domain LRR_6 PF13516.6 KLO10490.1 - 0.14 12.3 0.0 5.6 7.3 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat FMN_dh PF01070.18 KLO10491.1 - 1.2e-110 369.9 0.0 1.4e-110 369.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KLO10491.1 - 2.4e-21 75.7 0.0 4.5e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.15 KLO10491.1 - 3e-06 26.9 0.0 4.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KLO10491.1 - 0.0001 21.6 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KLO10491.1 - 0.00011 21.4 0.1 0.00023 20.3 0.1 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Aminoglyc_resit PF10706.9 KLO10494.1 - 0.087 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase DDE_1 PF03184.19 KLO10496.1 - 2.4e-37 128.2 0.1 3.9e-37 127.6 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KLO10496.1 - 9.5e-10 38.4 0.1 2.2e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CBM_25 PF03423.13 KLO10498.1 - 0.14 12.4 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) DUF5495 PF17599.2 KLO10501.1 - 0.18 12.1 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5495) XRN_M PF17846.1 KLO10503.1 - 0.063 12.2 0.0 0.072 12.0 0.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF1088 PF06469.11 KLO10520.1 - 0.013 15.1 0.3 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1088) DEAD PF00270.29 KLO10525.1 - 3.5e-09 36.7 0.0 8.5e-07 28.9 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO10525.1 - 0.0014 19.0 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Par3_HAL_N_term PF12053.8 KLO10525.1 - 0.088 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins MMS22L_N PF14910.6 KLO10527.1 - 0.21 10.0 0.1 0.29 9.5 0.1 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal CPDase PF07823.11 KLO10528.1 - 3.1e-13 49.9 0.0 1.6e-12 47.6 0.0 1.9 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KLO10528.1 - 0.011 15.7 0.0 0.018 14.9 0.0 1.4 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KLO10528.1 - 0.072 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 LigT like Phosphoesterase MFS_1 PF07690.16 KLO10530.1 - 4.4e-21 75.2 27.7 5.5e-20 71.6 26.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Brix PF04427.18 KLO10531.1 - 3.4e-30 105.6 0.0 4.5e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF1776 PF08643.10 KLO10533.1 - 3e-09 36.7 0.0 4.7e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Adeno_PIX PF03955.14 KLO10533.1 - 0.19 11.9 3.2 2.4 8.3 0.0 2.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) KH_1 PF00013.29 KLO10534.1 - 1.1e-43 146.9 9.4 2e-17 62.8 0.5 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KLO10534.1 - 4e-14 52.2 6.6 2.9e-05 23.8 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KLO10534.1 - 4.3e-05 23.3 1.5 0.51 10.2 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KLO10534.1 - 0.0063 16.6 5.5 5.4 7.2 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain A_deaminase PF00962.22 KLO10535.1 - 4.2e-23 82.2 0.0 8e-22 78.0 0.0 2.3 2 0 0 2 2 2 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KLO10535.1 - 0.00021 21.5 0.0 0.00048 20.4 0.0 1.6 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Retrotran_gag_2 PF14223.6 KLO10535.1 - 2.3 7.9 5.4 0.99 9.1 0.2 2.6 3 1 0 3 3 3 0 gag-polypeptide of LTR copia-type NmrA PF05368.13 KLO10536.1 - 6.4e-43 147.0 0.3 8.5e-43 146.6 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO10536.1 - 1.7e-13 50.9 0.4 3e-13 50.0 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KLO10536.1 - 2.1e-05 23.7 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KLO10536.1 - 0.00017 21.2 0.1 0.00027 20.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KLO10536.1 - 0.0023 18.4 0.8 0.04 14.3 0.1 2.6 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KLO10536.1 - 0.0074 16.4 0.1 0.016 15.3 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KLO10536.1 - 0.044 13.2 1.0 0.32 10.4 0.3 2.5 3 0 0 3 3 3 0 short chain dehydrogenase adh_short_C2 PF13561.6 KLO10536.1 - 0.054 13.0 2.8 0.53 9.8 0.6 2.6 2 1 1 3 3 3 0 Enoyl-(Acyl carrier protein) reductase A_deaminase PF00962.22 KLO10537.1 - 8.5e-24 84.5 0.0 4.9e-22 78.7 0.0 2.5 2 1 0 2 2 2 2 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KLO10537.1 - 0.00031 21.0 0.0 0.00067 19.9 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Amidohydro_1 PF01979.20 KLO10537.1 - 0.017 14.5 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase family A_deaminase PF00962.22 KLO10538.1 - 1.7e-23 83.5 0.0 4.5e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KLO10538.1 - 0.00062 20.0 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal LZ3wCH PF18517.1 KLO10538.1 - 0.041 14.0 0.1 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 Leucine zipper with capping helix domain Vps54 PF07928.12 KLO10539.1 - 3.9e-52 176.2 0.1 3.9e-52 176.2 0.1 2.7 3 0 0 3 3 3 1 Vps54-like protein DUF2451 PF10474.9 KLO10539.1 - 0.00011 22.1 1.7 0.00021 21.2 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KLO10539.1 - 0.0011 18.3 0.1 0.0027 17.0 0.1 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Tropomyosin_1 PF12718.7 KLO10539.1 - 0.034 14.3 0.7 0.12 12.6 0.7 1.9 1 0 0 1 1 1 0 Tropomyosin like Ecl1 PF12855.7 KLO10541.1 - 0.015 16.5 23.8 0.015 16.5 23.8 4.0 1 1 3 4 4 4 0 ECL1/2/3 zinc binding proteins PLATZ PF04640.14 KLO10541.1 - 0.29 11.8 1.7 0.66 10.6 1.7 1.6 1 0 0 1 1 1 0 PLATZ transcription factor CENP-F_N PF10481.9 KLO10541.1 - 0.7 9.5 2.8 1.3 8.6 2.8 1.4 1 0 0 1 1 1 0 Cenp-F N-terminal domain WD40 PF00400.32 KLO10545.1 - 2.6e-29 100.8 16.3 7.6e-07 29.7 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO10545.1 - 7.5e-12 45.4 4.2 0.0032 17.7 0.1 4.7 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KLO10545.1 - 0.084 11.4 0.0 0.27 9.7 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain Elongin_A PF06881.11 KLO10546.1 - 2.1e-18 66.8 0.0 4.5e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Gti1_Pac2 PF09729.9 KLO10547.1 - 7.4e-31 107.6 0.5 1.3e-28 100.3 0.1 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family cwf18 PF08315.12 KLO10548.1 - 1e-31 110.4 15.7 1.4e-31 110.0 15.7 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor SIR4_SID PF16991.5 KLO10548.1 - 0.061 13.4 1.8 0.086 12.9 1.7 1.3 1 1 0 1 1 1 0 Sir4 SID domain Tweety PF04906.13 KLO10548.1 - 0.32 9.6 0.6 0.41 9.2 0.7 1.3 1 1 0 1 1 1 0 Tweety Bud13 PF09736.9 KLO10548.1 - 6.8 7.1 12.6 2.2 8.6 3.8 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex LepA_C PF06421.12 KLO10549.1 - 4.7e-43 145.7 0.1 7.9e-43 145.0 0.1 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 KLO10549.1 - 2.8e-28 98.8 0.0 4.2e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KLO10549.1 - 2.9e-16 59.3 0.0 6.5e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KLO10549.1 - 1.8e-09 37.9 0.1 3.3e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KLO10549.1 - 5e-06 26.5 0.0 9.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 KLO10549.1 - 6.3e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ras PF00071.22 KLO10549.1 - 0.0018 17.9 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KLO10549.1 - 0.011 15.8 0.0 0.031 14.4 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase IF-2B PF01008.17 KLO10550.1 - 8.8e-64 215.4 0.0 1e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Mur_ligase PF01225.25 KLO10550.1 - 0.019 15.3 0.1 0.058 13.7 0.0 1.8 2 0 0 2 2 2 0 Mur ligase family, catalytic domain CK2S PF15011.6 KLO10550.1 - 0.051 13.5 0.3 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 Casein Kinase 2 substrate GATase_6 PF13522.6 KLO10551.1 - 1.7e-13 50.9 0.0 3.5e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KLO10551.1 - 3.5e-12 46.3 0.0 6.2e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KLO10551.1 - 1.5e-10 40.8 0.1 2.4e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KLO10551.1 - 6.7e-06 25.2 0.0 2.1e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 Glutamine amidotransferases class-II Myotub-related PF06602.14 KLO10552.1 - 2.1e-150 500.6 0.1 2.6e-150 500.2 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KLO10552.1 - 0.061 12.9 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase HTH_29 PF13551.6 KLO10552.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix S-AdoMet_synt_C PF02773.16 KLO10553.1 - 2.1e-67 225.3 0.5 5.3e-67 224.1 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KLO10553.1 - 3.5e-47 159.6 0.0 6.4e-47 158.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KLO10553.1 - 3.3e-45 152.8 1.6 9.4e-45 151.4 0.3 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KLO10553.1 - 0.039 12.7 0.2 0.15 10.8 0.0 1.8 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Trp_syntA PF00290.20 KLO10554.1 - 1.5e-81 273.1 1.1 2.3e-81 272.4 1.1 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KLO10554.1 - 1.7e-45 155.7 0.2 2.6e-45 155.1 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 KLO10554.1 - 0.00046 19.7 0.1 0.0011 18.5 0.1 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein PA PF02225.22 KLO10554.1 - 0.0043 17.0 0.8 4.9 7.2 0.0 2.8 2 0 0 2 2 2 2 PA domain NMO PF03060.15 KLO10554.1 - 0.0094 15.4 0.2 0.021 14.2 0.2 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase Asparaginase PF00710.20 KLO10555.1 - 7e-56 188.8 0.0 6.4e-55 185.7 0.0 2.4 2 1 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KLO10555.1 - 6e-31 107.0 0.0 1.1e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KLO10555.1 - 1.1e-12 48.4 0.0 2.8e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KLO10555.1 - 2.6e-11 43.4 1.1 0.00023 21.5 0.2 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KLO10555.1 - 5.1e-11 42.9 0.0 4.5e-07 30.3 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KLO10555.1 - 8.7e-08 31.9 0.8 0.034 14.7 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KLO10555.1 - 3e-05 24.2 1.5 0.011 16.1 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Csm1 PF12539.8 KLO10556.1 - 1.9e-05 25.2 0.1 3.8e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 MbeD_MobD PF04899.12 KLO10556.1 - 0.00015 21.8 12.5 0.0022 18.0 0.6 3.2 3 0 0 3 3 3 2 MbeD/MobD like HALZ PF02183.18 KLO10556.1 - 0.0051 17.0 4.1 0.048 13.9 1.1 2.9 2 0 0 2 2 2 1 Homeobox associated leucine zipper Golgin_A5 PF09787.9 KLO10556.1 - 0.034 13.6 20.5 0.063 12.7 20.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Flagellin_C PF00700.21 KLO10556.1 - 0.047 14.0 2.5 0.23 11.9 2.5 2.2 2 0 0 2 2 1 0 Bacterial flagellin C-terminal helical region ADIP PF11559.8 KLO10556.1 - 0.075 13.1 22.7 0.25 11.4 5.4 2.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GTP-bdg_M PF16360.5 KLO10556.1 - 0.28 11.8 10.7 0.23 12.1 3.0 2.7 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region BLOC1_2 PF10046.9 KLO10556.1 - 0.69 10.3 13.2 0.6 10.4 6.7 2.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HSCB_C PF07743.13 KLO10556.1 - 0.76 10.3 16.6 0.066 13.7 4.3 3.2 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain DUF2730 PF10805.8 KLO10556.1 - 3.1 7.9 7.5 17 5.6 0.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) TRAF_BIRC3_bd PF16673.5 KLO10556.1 - 4 7.3 9.0 7 6.5 1.0 2.8 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF1993 PF09351.10 KLO10556.1 - 4.9 7.3 6.8 3 8.0 3.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) PikAIV_N PF18605.1 KLO10556.1 - 5 6.8 10.3 0.29 10.8 3.4 2.6 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain JIP_LZII PF16471.5 KLO10556.1 - 6.2 7.1 15.3 2 8.6 6.5 2.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Jnk-SapK_ap_N PF09744.9 KLO10556.1 - 6.5 7.0 27.5 2.3 8.4 6.0 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 KLO10556.1 - 8 4.9 5.7 13 4.2 5.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family WXG100 PF06013.12 KLO10556.1 - 8.1 6.7 10.6 3.1 8.1 0.6 3.7 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Cu_bind_like PF02298.17 KLO10557.1 - 0.0032 17.4 0.3 0.0094 16.0 0.3 1.7 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 KLO10557.1 - 0.011 16.2 0.1 0.021 15.3 0.1 1.4 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family MSP PF01716.18 KLO10557.1 - 0.07 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide G-gamma PF00631.22 KLO10558.1 - 1.1e-21 76.6 0.0 1.2e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 GGL domain Thioredoxin PF00085.20 KLO10559.1 - 1.7e-27 95.4 0.0 2.2e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KLO10559.1 - 6.9e-10 39.3 0.3 8.4e-09 35.8 0.1 2.5 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KLO10559.1 - 1e-05 25.8 0.0 0.0017 18.6 0.0 2.6 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KLO10559.1 - 0.0039 17.3 0.0 0.0087 16.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KLO10559.1 - 0.0065 16.3 0.0 0.011 15.6 0.0 1.4 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KLO10559.1 - 0.0074 16.1 0.0 0.015 15.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KLO10559.1 - 0.0081 16.1 0.1 0.03 14.2 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Mating_N PF12731.7 KLO10559.1 - 0.039 14.0 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein beta 1 Redoxin PF08534.10 KLO10559.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.7 1 1 1 2 2 2 0 Redoxin OST3_OST6 PF04756.13 KLO10559.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family G-gamma PF00631.22 KLO10560.1 - 1.2e-19 70.1 0.0 1.3e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 GGL domain DUF1386 PF07138.11 KLO10561.1 - 0.027 13.7 0.6 0.039 13.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1386) DUF684 PF05075.14 KLO10561.1 - 0.064 12.2 0.1 0.41 9.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF684) MFS_1 PF07690.16 KLO10562.1 - 6.6e-21 74.6 53.2 3.6e-18 65.6 39.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 KLO10562.1 - 0.035 14.1 0.6 0.17 11.9 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage P21 holin S TRAM_LAG1_CLN8 PF03798.16 KLO10563.1 - 2.1e-30 105.9 13.6 2.1e-30 105.9 13.6 1.5 2 0 0 2 2 2 1 TLC domain GST_C_6 PF17171.4 KLO10564.1 - 2.5e-13 49.6 0.0 4.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KLO10564.1 - 5.5e-05 23.8 0.0 9.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KLO10564.1 - 0.00036 20.8 0.0 0.00064 20.0 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KLO10564.1 - 0.0066 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cys_Met_Meta_PP PF01053.20 KLO10565.1 - 9.7e-116 386.4 0.0 1.9e-90 303.1 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KLO10565.1 - 0.0055 15.9 0.0 0.0087 15.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 KLO10565.1 - 0.029 12.9 0.0 0.047 12.2 0.0 1.3 1 1 0 1 1 1 0 Methionine gamma-lyase EF1_GNE PF00736.19 KLO10566.1 - 5.6e-33 113.0 1.2 1.1e-32 112.1 1.2 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KLO10566.1 - 2e-12 47.3 9.2 2e-12 47.3 9.2 2.1 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 KLO10566.1 - 0.0017 18.5 0.3 0.45 10.8 0.0 3.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO10566.1 - 0.019 15.2 0.1 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KLO10566.1 - 0.024 14.7 0.0 0.22 11.6 0.0 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cnd2 PF05786.14 KLO10566.1 - 0.068 11.8 2.4 0.088 11.5 2.4 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Syja_N PF02383.18 KLO10567.1 - 7.7e-90 301.4 0.0 1.1e-89 300.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KLO10567.1 - 9.8e-30 102.6 0.0 2.2e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase Pet100 PF09803.9 KLO10568.1 - 4.3e-24 84.8 0.0 5.6e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Pet100 PALP PF00291.25 KLO10569.1 - 5.7e-59 199.9 0.0 6.6e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peripla_BP_6 PF13458.6 KLO10569.1 - 0.022 14.5 0.0 5.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein Glyco_tran_WecB PF03808.13 KLO10569.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family DUF4072 PF13284.6 KLO10569.1 - 0.15 12.5 0.1 0.66 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) Glyco_hydro_31 PF01055.26 KLO10570.1 - 5.5e-113 378.5 0.3 7.1e-113 378.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KLO10570.1 - 3e-18 65.9 0.3 8.3e-18 64.5 0.1 1.9 2 0 0 2 2 2 1 Galactose mutarotase-like DUF4968 PF16338.5 KLO10570.1 - 0.064 13.6 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) zf-MYND PF01753.18 KLO10573.1 - 3.1e-12 46.4 25.4 2.6e-09 37.0 11.5 2.9 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.6 KLO10573.1 - 0.0057 16.7 10.6 0.07 13.2 2.9 2.7 2 0 0 2 2 2 2 Zinc-finger of mitochondrial splicing suppressor 51 DUF629 PF04780.12 KLO10573.1 - 0.67 8.4 4.4 5.8 5.3 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Siva PF05458.12 KLO10573.1 - 5.9 6.5 11.6 0.21 11.3 4.5 1.9 2 0 0 2 2 2 0 Cd27 binding protein (Siva) F-box-like PF12937.7 KLO10577.1 - 2.7e-09 36.8 0.8 2.7e-09 36.8 0.8 2.8 3 0 0 3 3 3 1 F-box-like zf-MYND PF01753.18 KLO10578.1 - 1.8e-10 40.7 20.1 6.7e-08 32.5 8.3 2.7 2 0 0 2 2 2 2 MYND finger Ecl1 PF12855.7 KLO10578.1 - 0.016 16.4 1.4 0.016 16.4 1.4 1.6 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins zf-Mss51 PF13824.6 KLO10578.1 - 0.016 15.3 15.0 0.62 10.2 1.7 3.3 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-CHY PF05495.12 KLO10578.1 - 7.5 7.1 16.1 2.7 8.5 1.3 3.1 3 0 0 3 3 3 0 CHY zinc finger G-alpha PF00503.20 KLO10580.1 - 7.6e-103 344.4 0.0 9.6e-103 344.0 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO10580.1 - 3.2e-05 23.5 0.0 6.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Hva1_TUDOR PF11160.8 KLO10581.1 - 1.6e-08 34.5 0.1 2.5e-06 27.6 0.1 2.2 1 1 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain DUF1918 PF08940.11 KLO10581.1 - 0.0028 17.2 0.0 0.0039 16.8 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1918) Cript PF10235.9 KLO10583.1 - 1.4e-26 92.9 4.1 1.4e-26 92.9 4.1 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 KLO10583.1 - 0.033 14.2 13.4 0.11 12.5 9.9 2.4 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KLO10583.1 - 0.059 13.1 15.2 0.6 9.9 5.8 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DNA_primase_lrg PF04104.14 KLO10583.1 - 0.066 12.6 3.7 0.081 12.3 3.7 1.1 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit DUF2039 PF10217.9 KLO10583.1 - 1.2 9.5 14.3 0.39 11.1 8.8 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf_UBZ PF18439.1 KLO10583.1 - 3.4 7.3 8.8 4.5 7.0 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger PolC_DP2 PF03833.13 KLO10583.1 - 5.3 4.8 6.9 3.2 5.5 5.8 1.2 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 HEM4 PF02602.15 KLO10585.1 - 4.5e-33 114.5 0.1 5.5e-33 114.2 0.1 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Peptidase_C14 PF00656.22 KLO10585.1 - 0.024 14.6 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Caspase domain DUF2862 PF11061.8 KLO10585.1 - 0.06 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) Aldo_ket_red PF00248.21 KLO10586.1 - 1.4e-78 264.1 0.0 1.6e-78 263.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.27 KLO10587.1 - 2.2e-60 200.6 1.0 5.3e-22 77.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Myb_DNA-bind_3 PF12776.7 KLO10588.1 - 4.7e-17 62.8 0.4 7e-17 62.2 0.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KLO10588.1 - 3e-05 24.3 0.4 5.4e-05 23.5 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KLO10588.1 - 0.081 13.3 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Abhydrolase_1 PF00561.20 KLO10589.1 - 1.2e-16 61.2 0.0 1.2e-11 44.7 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KLO10589.1 - 1.6e-16 60.2 0.0 3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DUF1614 PF07758.11 KLO10589.1 - 0.11 12.4 0.2 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) zf-MYND PF01753.18 KLO10590.1 - 3.6e-08 33.4 16.2 3.6e-08 33.4 16.2 2.2 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 KLO10592.1 - 3.4e-10 39.9 25.2 6.6e-08 32.5 10.0 3.1 3 0 0 3 3 3 2 MYND finger zf-CHY PF05495.12 KLO10592.1 - 0.21 12.1 14.7 3.8 8.1 0.7 3.5 3 0 0 3 3 3 0 CHY zinc finger zf-Mss51 PF13824.6 KLO10592.1 - 2.2 8.4 11.2 2.9 8.0 1.2 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO10594.1 - 1.6e-07 31.3 20.6 2e-06 27.8 2.4 3.1 3 0 0 3 3 3 2 MYND finger zf-C6H2 PF15801.5 KLO10594.1 - 0.021 15.1 6.0 0.021 15.1 6.0 3.0 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KLO10594.1 - 0.031 14.4 11.2 0.41 10.8 1.2 2.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Chlamy_scaf PF09675.10 KLO10594.1 - 0.044 14.1 0.0 0.082 13.3 0.0 1.4 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) zf-WRNIP1_ubi PF18279.1 KLO10594.1 - 1.9 9.3 5.2 0.5 11.1 1.3 2.1 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-MYND PF01753.18 KLO10596.1 - 5.4e-07 29.6 24.1 1e-05 25.5 7.4 3.3 3 0 0 3 3 3 2 MYND finger zf-CHY PF05495.12 KLO10596.1 - 0.36 11.3 12.0 11 6.5 0.8 3.6 3 0 0 3 3 3 0 CHY zinc finger zf-Mss51 PF13824.6 KLO10596.1 - 5.4 7.2 10.8 8.4 6.6 1.4 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO10598.1 - 7.2e-08 32.4 5.7 7.2e-08 32.4 5.7 3.1 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.6 KLO10598.1 - 1.9 8.7 11.4 0.73 10.0 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO10600.1 - 3.3e-07 30.3 5.6 3.3e-07 30.3 5.6 3.2 3 0 0 3 3 3 2 MYND finger zf-MYND PF01753.18 KLO10601.1 - 3.2e-09 36.7 22.2 6e-07 29.5 5.9 3.0 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.6 KLO10601.1 - 0.0086 16.1 9.1 0.44 10.7 1.4 2.8 2 0 0 2 2 2 2 Zinc-finger of mitochondrial splicing suppressor 51 AMA-1 PF02430.15 KLO10601.1 - 0.055 12.4 0.7 0.08 11.9 0.7 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 zinc-ribbons_6 PF07191.12 KLO10601.1 - 2.1 8.4 11.4 8.4 6.5 2.9 2.7 2 0 0 2 2 2 0 zinc-ribbons zinc_ribbon_4 PF13717.6 KLO10601.1 - 9.9 6.2 8.1 30 4.6 0.4 3.7 3 0 0 3 3 3 0 zinc-ribbon domain RTA1 PF04479.13 KLO10602.1 - 1.6e-60 204.2 6.3 2.7e-60 203.5 6.3 1.3 1 0 0 1 1 1 1 RTA1 like protein zf-MYND PF01753.18 KLO10604.1 - 1.7e-08 34.4 17.7 1.7e-08 34.4 17.7 2.4 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KLO10604.1 - 9.1 6.7 12.2 25 5.3 12.2 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Abhydrolase_4 PF08386.10 KLO10605.1 - 1.2e-17 63.9 0.0 2.2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KLO10605.1 - 3.1e-16 59.8 0.0 2.6e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KLO10606.1 - 5.1e-18 65.6 0.0 1.4e-14 54.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KLO10606.1 - 1.5e-14 54.0 0.0 3.2e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein RNA_lig_T4_1 PF09511.10 KLO10607.1 - 6.5e-82 274.7 0.0 1.3e-81 273.7 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KLO10607.1 - 5e-28 98.3 0.4 1.1e-27 97.2 0.4 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 KLO10607.1 - 2.1e-21 76.5 0.0 1.5e-20 73.7 0.0 2.4 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain ANAPC4_WD40 PF12894.7 KLO10608.1 - 0.0011 19.2 0.0 6.8 7.1 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KLO10608.1 - 0.065 14.1 0.0 0.6 11.1 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat SET PF00856.28 KLO10609.1 - 4.2e-07 30.5 0.0 1.3e-06 28.9 0.0 1.8 1 1 0 1 1 1 1 SET domain DUF1682 PF07946.14 KLO10610.1 - 0.16 11.2 2.8 0.24 10.5 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Kinesin_assoc PF16183.5 KLO10610.1 - 0.99 9.5 4.2 0.79 9.8 0.9 2.1 2 0 0 2 2 2 0 Kinesin-associated DUF3381 PF11861.8 KLO10610.1 - 1.4 8.7 10.6 5.4 6.8 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) AP3D1 PF06375.11 KLO10610.1 - 4.5 7.5 8.5 12 6.1 0.4 3.3 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 Exo70 PF03081.15 KLO10611.1 - 4.6e-41 141.1 0.0 7.3e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Urb2 PF10441.9 KLO10611.1 - 0.00042 20.3 0.3 0.035 14.0 0.2 2.9 3 0 0 3 3 3 1 Urb2/Npa2 family Snapin_Pallidin PF14712.6 KLO10611.1 - 0.64 10.5 5.6 0.31 11.5 0.8 2.9 4 0 0 4 4 4 0 Snapin/Pallidin Abhydrolase_1 PF00561.20 KLO10612.1 - 1.5e-21 77.2 0.2 2.5e-21 76.5 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3176 PF11374.8 KLO10613.1 - 0.0076 16.4 13.3 0.11 12.7 0.8 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3176) Gelsolin PF00626.22 KLO10614.1 - 5.7e-32 109.5 0.0 7.9e-15 54.5 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat zf-C2H2 PF00096.26 KLO10615.1 - 3e-12 46.3 10.6 3e-06 27.4 1.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KLO10615.1 - 8.8e-09 35.4 16.4 1.1e-06 28.8 2.9 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KLO10615.1 - 5.9e-08 32.9 8.8 0.0016 19.1 1.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KLO10615.1 - 0.0086 16.2 0.7 0.72 10.0 0.1 2.0 1 1 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KLO10615.1 - 0.022 15.1 0.5 0.029 14.7 0.5 1.3 1 1 0 1 1 1 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KLO10615.1 - 0.023 15.3 0.5 7.2 7.3 0.1 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KLO10615.1 - 0.34 10.7 13.3 1.7 8.5 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain DUF1435 PF07256.12 KLO10616.1 - 0.042 14.0 0.5 0.87 9.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) WD40 PF00400.32 KLO10617.1 - 6.2e-16 58.5 12.2 1.1e-05 26.1 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat APS_kinase PF01583.20 KLO10619.1 - 0.00025 21.0 0.1 0.00033 20.6 0.1 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 KLO10619.1 - 0.00029 21.3 0.0 0.00031 21.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KLO10619.1 - 0.017 14.8 0.1 0.03 14.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KLO10619.1 - 0.018 14.9 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KLO10619.1 - 0.02 15.4 0.0 0.023 15.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 KLO10619.1 - 0.027 13.6 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.17 KLO10619.1 - 0.035 13.2 0.0 0.039 13.0 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 KLO10619.1 - 0.037 14.2 0.1 0.049 13.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KLO10619.1 - 0.069 13.1 0.0 0.083 12.9 0.0 1.1 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KLO10619.1 - 0.079 12.7 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KLO10619.1 - 0.09 13.0 0.0 0.097 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KLO10619.1 - 0.13 12.6 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Thymidylate_kin PF02223.17 KLO10619.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase NACHT PF05729.12 KLO10620.1 - 7.5e-05 22.7 1.1 0.00024 21.1 1.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO10620.1 - 0.00096 19.6 0.1 0.0016 18.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 KLO10620.1 - 0.0081 16.2 0.0 0.013 15.6 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain KAP_NTPase PF07693.14 KLO10620.1 - 0.0086 15.4 0.4 0.013 14.8 0.3 1.2 1 1 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 KLO10620.1 - 0.035 14.4 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KLO10621.1 - 1e-06 28.8 2.8 1.1e-05 25.4 2.8 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO10621.1 - 0.0024 18.3 0.1 0.0098 16.3 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KLO10621.1 - 0.0063 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KLO10621.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 KLO10621.1 - 0.13 10.9 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_30 PF13604.6 KLO10621.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KLO10621.1 - 0.19 12.0 0.1 0.47 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KLO10621.1 - 0.21 12.0 0.3 1 9.8 0.1 2.0 2 0 0 2 2 2 0 RNA helicase Parvo_NS1 PF01057.17 KLO10622.1 - 0.00089 18.4 0.0 0.00089 18.4 0.0 1.0 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NACHT PF05729.12 KLO10623.1 - 8.1e-18 64.9 0.0 1.5e-10 41.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO10623.1 - 2.5e-09 37.7 2.7 3.7e-05 24.2 0.1 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KLO10623.1 - 2.4e-07 31.1 0.0 0.0021 18.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KLO10623.1 - 2.1e-06 28.2 0.0 0.0014 19.1 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KLO10623.1 - 1.3e-05 24.6 0.1 0.00049 19.5 0.0 2.5 2 0 0 2 2 2 1 KAP family P-loop domain Zeta_toxin PF06414.12 KLO10623.1 - 0.00061 19.1 0.3 0.85 8.9 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin NB-ARC PF00931.22 KLO10623.1 - 0.0019 17.4 0.0 1.7 7.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain APS_kinase PF01583.20 KLO10623.1 - 0.0068 16.3 0.4 0.13 12.2 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase PIF1 PF05970.14 KLO10623.1 - 0.0099 15.1 0.1 0.69 9.0 0.0 2.9 3 0 0 3 3 3 1 PIF1-like helicase AAA_30 PF13604.6 KLO10623.1 - 0.016 14.9 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KLO10623.1 - 0.016 14.3 0.2 0.56 9.2 0.1 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Torsin PF06309.11 KLO10623.1 - 0.023 14.8 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Torsin HH_signal PF01085.18 KLO10623.1 - 0.025 14.2 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain ABC_tran PF00005.27 KLO10623.1 - 0.045 14.3 0.0 0.22 12.0 0.0 2.2 2 0 0 2 2 1 0 ABC transporter AAA_18 PF13238.6 KLO10623.1 - 0.12 12.9 0.4 0.62 10.6 0.1 2.5 2 1 0 2 2 1 0 AAA domain CbiA PF01656.23 KLO10623.1 - 0.45 10.6 1.4 45 4.1 0.2 3.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 KLO10624.1 - 8.9e-20 71.3 0.9 1.5e-08 34.7 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_16 PF13191.6 KLO10624.1 - 6.5e-09 36.4 0.9 0.00018 22.0 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KLO10624.1 - 2.5e-07 31.0 0.0 0.00026 21.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KLO10624.1 - 1.9e-05 25.1 0.0 0.0037 17.7 0.0 3.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KLO10624.1 - 0.001 18.4 1.6 0.021 14.1 0.0 2.6 2 1 0 3 3 3 1 KAP family P-loop domain NB-ARC PF00931.22 KLO10624.1 - 0.0011 18.3 0.0 0.22 10.7 0.0 2.8 2 1 0 2 2 2 1 NB-ARC domain Parvo_NS1 PF01057.17 KLO10624.1 - 0.0024 17.0 0.2 0.44 9.6 0.1 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 APS_kinase PF01583.20 KLO10624.1 - 0.0032 17.4 0.3 0.039 13.8 0.1 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.6 KLO10624.1 - 0.0075 16.8 0.8 0.69 10.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain Torsin PF06309.11 KLO10624.1 - 0.012 15.7 0.0 1.3 9.1 0.0 3.4 3 0 0 3 3 3 0 Torsin ABC_tran PF00005.27 KLO10624.1 - 0.017 15.6 0.1 0.061 13.8 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_30 PF13604.6 KLO10624.1 - 0.023 14.4 0.1 0.066 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 KLO10624.1 - 0.034 13.3 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase RNA_helicase PF00910.22 KLO10624.1 - 0.082 13.3 0.0 2 8.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KLO10626.1 - 2.9e-10 40.3 0.1 2.1e-09 37.5 0.0 2.4 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 KLO10626.1 - 8.1e-05 22.9 0.0 0.013 15.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO10626.1 - 0.00026 21.4 0.1 0.0017 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KLO10626.1 - 0.00054 20.4 0.0 0.002 18.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KLO10626.1 - 0.012 16.1 0.0 0.039 14.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter BLI1 PF17324.2 KLO10626.1 - 0.016 15.9 1.8 0.023 15.3 0.6 1.9 2 0 0 2 2 1 0 BLOC-1 interactor 1 APS_kinase PF01583.20 KLO10626.1 - 0.02 14.8 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KLO10626.1 - 0.038 13.2 0.2 0.2 10.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MutS_III PF05192.18 KLO10626.1 - 0.057 13.6 1.2 0.18 12.0 0.5 2.2 2 1 0 2 2 2 0 MutS domain III AAA_30 PF13604.6 KLO10626.1 - 0.067 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KLO10626.1 - 0.11 12.4 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase RuvX PF03652.15 KLO10626.1 - 0.12 12.8 0.0 40 4.6 0.0 3.0 3 0 0 3 3 3 0 Holliday junction resolvase Torsin PF06309.11 KLO10626.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Torsin NACHT PF05729.12 KLO10627.1 - 4.7e-09 36.4 0.1 4e-08 33.4 0.0 2.4 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KLO10627.1 - 1.7e-07 31.8 0.2 3.6e-06 27.5 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KLO10627.1 - 0.00042 20.6 0.0 0.0014 18.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KLO10627.1 - 0.0033 17.4 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_tran PF00005.27 KLO10627.1 - 0.005 17.4 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KLO10627.1 - 0.0065 16.2 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KLO10627.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KLO10627.1 - 0.026 13.6 0.1 0.047 12.7 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KLO10627.1 - 0.029 14.9 0.3 0.063 13.8 0.1 1.6 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 KLO10627.1 - 0.03 14.7 0.0 0.095 13.1 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_24 PF13479.6 KLO10627.1 - 0.038 13.7 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KLO10627.1 - 0.094 11.9 0.9 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA PF00004.29 KLO10627.1 - 0.095 13.1 0.4 0.44 11.0 0.4 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KLO10627.1 - 0.097 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_PrkA PF08298.11 KLO10627.1 - 0.14 11.0 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain APS_kinase PF01583.20 KLO10627.1 - 0.16 11.9 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 KLO10627.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATP_bind_1 PF03029.17 KLO10627.1 - 0.17 11.6 0.3 0.87 9.3 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KLO10628.1 - 2e-06 27.8 1.4 9.1e-06 25.7 0.4 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KLO10628.1 - 0.00052 20.4 0.6 0.0015 18.9 0.5 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KLO10628.1 - 0.069 13.6 0.0 0.23 11.9 0.0 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO10628.1 - 0.085 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KLO10629.1 - 4.3e-10 39.8 0.0 1.4e-09 38.1 0.0 1.9 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KLO10629.1 - 8.2e-06 26.3 0.6 2.7e-05 24.6 0.1 2.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KLO10629.1 - 0.00024 21.4 0.1 0.0025 18.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KLO10629.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.6 KLO10629.1 - 0.0018 18.0 0.1 0.004 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KLO10629.1 - 0.0021 18.6 0.0 0.0044 17.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 KLO10629.1 - 0.0045 17.4 0.0 0.02 15.3 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 KLO10629.1 - 0.0084 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_18 PF13238.6 KLO10629.1 - 0.01 16.3 0.1 0.26 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KLO10629.1 - 0.014 14.5 0.1 0.025 13.7 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KLO10629.1 - 0.018 14.2 0.2 0.13 11.4 0.0 2.4 2 1 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 KLO10629.1 - 0.023 14.4 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_PrkA PF08298.11 KLO10629.1 - 0.024 13.6 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Torsin PF06309.11 KLO10629.1 - 0.035 14.2 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Torsin AAA_24 PF13479.6 KLO10629.1 - 0.042 13.6 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KLO10629.1 - 0.082 12.9 0.0 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Abhydrolase_1 PF00561.20 KLO10632.1 - 4.2e-17 62.7 0.1 7.6e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KLO10632.1 - 6.9e-15 55.0 0.1 1.8e-14 53.7 0.1 1.7 1 1 0 1 1 1 1 TAP-like protein Putative_PNPOx PF01243.20 KLO10633.1 - 0.00021 21.4 0.0 0.068 13.4 0.0 2.6 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 KLO10633.1 - 0.00055 20.6 0.0 0.0027 18.3 0.0 2.1 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KLO10633.1 - 0.004 17.3 0.0 0.0087 16.2 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NACHT PF05729.12 KLO10635.1 - 6.8e-15 55.4 0.1 1.4e-09 38.1 0.0 3.4 3 1 0 3 3 3 2 NACHT domain AAA_22 PF13401.6 KLO10635.1 - 1.9e-09 37.9 0.0 0.002 18.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KLO10635.1 - 8.7e-09 36.0 0.0 0.0061 17.0 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain Parvo_NS1 PF01057.17 KLO10635.1 - 2.9e-06 26.6 0.1 0.037 13.1 0.1 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KLO10635.1 - 2.7e-05 24.0 0.0 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KLO10635.1 - 0.00021 21.7 0.0 0.27 11.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 KLO10635.1 - 0.00071 20.0 0.3 0.28 11.6 0.0 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KLO10635.1 - 0.00082 19.1 0.0 0.045 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KLO10635.1 - 0.0016 17.7 0.0 0.15 11.2 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 KLO10635.1 - 0.0025 17.7 0.4 0.5 10.2 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase IstB_IS21 PF01695.17 KLO10635.1 - 0.011 15.5 0.1 0.64 9.7 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 KLO10635.1 - 0.012 16.2 0.0 0.14 12.6 0.0 2.7 3 0 0 3 3 3 0 ABC transporter AAA_18 PF13238.6 KLO10635.1 - 0.015 15.8 0.0 2.5 8.6 0.0 3.4 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 KLO10635.1 - 0.026 14.1 0.0 0.91 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KLO10635.1 - 0.035 13.9 0.1 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Rad17 PF03215.15 KLO10635.1 - 0.054 13.4 0.0 2.2 8.2 0.0 2.8 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_29 PF13555.6 KLO10635.1 - 0.056 13.2 0.0 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain PhoH PF02562.16 KLO10635.1 - 0.086 12.3 0.0 3 7.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 KLO10635.1 - 0.11 12.4 0.0 7.7 6.4 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_PrkA PF08298.11 KLO10635.1 - 0.13 11.1 0.0 0.53 9.1 0.0 1.9 2 0 0 2 2 2 0 PrkA AAA domain PSS PF03034.15 KLO10635.1 - 0.19 11.5 1.8 2 8.1 0.4 2.3 2 0 0 2 2 2 0 Phosphatidyl serine synthase adh_short PF00106.25 KLO10636.1 - 3.7e-45 153.8 1.4 5e-45 153.4 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO10636.1 - 1e-34 120.1 0.7 1.4e-34 119.7 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO10636.1 - 2.3e-13 50.5 0.4 4.5e-13 49.5 0.4 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KLO10636.1 - 0.0016 18.4 2.2 0.0034 17.3 0.7 2.2 2 2 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KLO10636.1 - 0.002 17.8 0.1 0.0041 16.8 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KLO10636.1 - 0.0023 17.3 0.1 0.076 12.4 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KLO10636.1 - 0.034 13.6 0.3 0.05 13.1 0.3 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KLO10636.1 - 0.038 13.3 0.1 0.095 12.0 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_Gly3P_dh_N PF01210.23 KLO10636.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KLO10636.1 - 0.14 12.2 0.4 0.49 10.5 0.2 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DFP PF04127.15 KLO10636.1 - 0.15 11.9 1.2 0.47 10.3 1.2 1.7 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF676 PF05057.14 KLO10637.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF829 PF05705.14 KLO10637.1 - 0.026 14.4 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Cutinase PF01083.22 KLO10637.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.7 KLO10637.1 - 0.091 13.4 0.3 0.25 11.9 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family UIM PF02809.20 KLO10637.1 - 0.36 10.9 0.7 26 5.0 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif PGAP1 PF07819.13 KLO10638.1 - 3.7e-07 30.1 0.0 7.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KLO10638.1 - 3.5e-05 23.4 0.0 6.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KLO10638.1 - 9.7e-05 23.1 0.0 0.00013 22.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO10638.1 - 0.0067 15.7 0.1 0.024 13.9 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KLO10638.1 - 0.0079 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Cutinase PF01083.22 KLO10638.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase AAA_16 PF13191.6 KLO10639.1 - 3.2e-06 27.6 0.2 4.4e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KLO10639.1 - 6.8e-06 25.5 0.1 7.4e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.12 KLO10639.1 - 0.0063 16.4 1.2 0.021 14.8 1.2 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KLO10639.1 - 0.011 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain FAM220 PF15487.6 KLO10639.1 - 0.043 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 FAM220 family APS_kinase PF01583.20 KLO10639.1 - 0.15 12.0 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Pkinase_fungal PF17667.1 KLO10640.1 - 1.1e-71 241.8 0.0 2.4e-71 240.7 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO10640.1 - 5.2e-10 39.1 0.0 3.6e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KLO10640.1 - 0.00019 20.8 0.0 0.0012 18.2 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KLO10640.1 - 0.00034 20.0 0.0 0.00066 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO10640.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KLO10640.1 - 0.047 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family adh_short PF00106.25 KLO10641.1 - 9.9e-45 152.4 0.5 1.3e-44 152.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO10641.1 - 1.6e-33 116.2 0.1 1.9e-33 116.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO10641.1 - 5.1e-07 29.8 0.2 8.4e-07 29.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KLO10641.1 - 0.0036 16.5 0.2 0.0045 16.2 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KLO10641.1 - 0.0066 15.9 0.4 0.027 13.9 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KLO10641.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) zf-RING_4 PF14570.6 KLO10642.1 - 1.3e-21 76.2 12.7 2.1e-21 75.4 12.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KLO10642.1 - 6e-07 29.2 9.7 1e-06 28.5 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO10642.1 - 0.00026 20.8 9.3 0.021 14.7 9.4 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KLO10642.1 - 0.00094 19.5 12.9 0.0016 18.7 12.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-UDP PF14569.6 KLO10642.1 - 0.087 12.9 4.0 0.19 11.8 4.0 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 KLO10642.1 - 0.094 12.7 4.3 0.18 11.8 4.3 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) RRM_1 PF00076.22 KLO10642.1 - 0.15 11.9 0.0 0.44 10.4 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.25 KLO10642.1 - 0.28 11.1 12.2 0.5 10.3 12.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO10642.1 - 0.41 10.7 7.4 0.64 10.1 6.4 1.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KLO10642.1 - 0.65 9.9 12.0 1.2 9.0 12.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) dsDNA_bind PF01984.20 KLO10643.1 - 5.3e-29 100.7 6.3 6.1e-29 100.5 6.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain NUDIX PF00293.28 KLO10643.1 - 0.056 13.5 2.9 0.085 12.9 2.8 1.4 1 1 0 1 1 1 0 NUDIX domain TBP PF00352.21 KLO10644.1 - 7.6e-67 221.3 0.3 1.1e-32 111.8 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KLO10644.1 - 3.6e-05 23.8 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KLO10644.1 - 0.045 13.6 0.0 0.16 11.8 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) F-box-like PF12937.7 KLO10645.1 - 0.00097 19.0 0.1 0.0023 17.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KLO10645.1 - 0.24 11.6 0.7 10 6.5 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat DNApol_Exo PF18136.1 KLO10646.1 - 2.8e-103 344.9 0.3 7.2e-103 343.6 0.4 1.6 2 0 0 2 2 2 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KLO10646.1 - 2.4e-47 161.8 0.0 3.8e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A Med26_C PF15693.5 KLO10646.1 - 0.11 12.7 0.1 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 26 C-terminal Cu_bind_like PF02298.17 KLO10648.1 - 0.028 14.4 1.8 0.083 12.9 0.6 2.3 2 1 0 2 2 2 0 Plastocyanin-like domain Glyco_hydro_88 PF07470.13 KLO10657.1 - 1.3e-12 47.5 0.1 1.8e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Dynamin_M PF01031.20 KLO10658.1 - 3.7e-102 341.4 0.1 8.4e-102 340.2 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KLO10658.1 - 2e-55 187.4 0.0 3.5e-55 186.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KLO10658.1 - 7.2e-27 93.4 4.4 7.2e-27 93.4 4.4 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KLO10658.1 - 0.00015 21.9 0.1 0.00084 19.4 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KLO10658.1 - 0.044 13.5 1.4 0.49 10.0 0.1 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_16 PF13191.6 KLO10658.1 - 0.11 12.9 0.1 1 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain NTF2 PF02136.20 KLO10659.1 - 3e-27 95.6 0.5 3.5e-27 95.3 0.5 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 KLO10659.1 - 0.014 15.8 0.0 0.019 15.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) MUG113 PF13455.6 KLO10661.1 - 1.9e-06 28.5 0.0 4.6e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KLO10661.1 - 0.00013 22.5 0.0 0.0021 18.6 0.0 2.7 2 0 0 2 2 2 1 T5orf172 domain DUF1797 PF08796.10 KLO10661.1 - 0.22 11.6 0.7 0.91 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) DUF4611 PF15387.6 KLO10661.1 - 2.3 8.5 20.9 3.1 8.1 9.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Nop14 PF04147.12 KLO10661.1 - 7.1 4.7 13.8 10 4.2 13.8 1.2 1 0 0 1 1 1 0 Nop14-like family MUG113 PF13455.6 KLO10662.1 - 1.4e-13 51.3 0.0 5.9e-13 49.3 0.0 2.1 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KLO10662.1 - 1.2e-10 41.9 0.0 1.3e-09 38.5 0.0 2.4 1 1 1 2 2 2 1 T5orf172 domain zf-primase PF09329.11 KLO10662.1 - 0.0066 16.2 0.3 0.021 14.6 0.3 1.9 1 1 0 1 1 1 1 Primase zinc finger Cu_bind_like PF02298.17 KLO10663.1 - 7.1e-05 22.7 7.5 0.15 12.1 0.9 3.8 2 2 0 2 2 2 2 Plastocyanin-like domain Cupredoxin_1 PF13473.6 KLO10663.1 - 0.0008 19.5 1.6 1.8 8.7 0.0 2.9 3 1 0 3 3 3 2 Cupredoxin-like domain Copper-bind PF00127.20 KLO10663.1 - 0.00098 19.5 4.0 0.31 11.5 0.2 3.6 3 2 0 3 3 3 2 Copper binding proteins, plastocyanin/azurin family Fer2_2 PF01799.20 KLO10663.1 - 0.038 14.0 1.5 0.83 9.7 0.1 2.6 2 0 0 2 2 2 0 [2Fe-2S] binding domain DUF5488 PF17590.2 KLO10663.1 - 2.1 8.1 0.0 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5488) zf-RING_UBOX PF13445.6 KLO10664.1 - 2.4e-09 37.1 6.2 5.5e-09 35.9 6.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KLO10664.1 - 2e-08 33.9 8.9 4.2e-08 32.9 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KLO10664.1 - 2.1e-07 31.0 8.2 4.8e-07 29.8 8.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KLO10664.1 - 3.1e-07 30.1 7.8 6e-07 29.2 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO10664.1 - 5.3e-06 26.2 6.2 9.5e-06 25.4 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO10664.1 - 9.5e-06 25.5 7.8 2e-05 24.4 7.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KLO10664.1 - 1.4e-05 25.3 9.0 3e-05 24.2 9.0 1.6 1 0 0 1 1 1 1 Ring finger domain SAP PF02037.27 KLO10664.1 - 0.00031 20.4 0.8 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 1 SAP domain SPATA24 PF15175.6 KLO10664.1 - 0.00077 19.4 0.9 0.002 18.1 0.2 2.0 1 1 0 1 1 1 1 Spermatogenesis-associated protein 24 zf-RING_6 PF14835.6 KLO10664.1 - 0.00078 19.3 3.2 0.0016 18.3 3.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KLO10664.1 - 0.00099 19.2 3.9 0.0022 18.1 3.9 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 KLO10664.1 - 0.08 13.1 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 U-box domain zf-RING_11 PF17123.5 KLO10664.1 - 0.27 11.0 7.7 0.67 9.8 7.7 1.7 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 KLO10664.1 - 0.4 10.6 8.2 1 9.3 8.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KLO10664.1 - 1 9.7 6.0 5.3 7.4 6.0 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KLO10664.1 - 3.7 7.4 6.0 10 6.0 6.0 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Glyco_transf_15 PF01793.16 KLO10665.1 - 3.5e-124 414.3 8.7 4.7e-124 413.9 8.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Porin_3 PF01459.22 KLO10666.1 - 1.6e-80 270.5 1.8 1.8e-80 270.3 1.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin ABC_tran PF00005.27 KLO10667.1 - 1.8e-26 93.3 0.0 2.3e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KLO10667.1 - 1.8e-06 28.0 0.0 0.056 13.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KLO10667.1 - 9.9e-06 25.6 0.2 0.0019 18.2 0.1 2.2 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.19 KLO10667.1 - 0.00014 21.4 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KLO10667.1 - 0.00017 21.5 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KLO10667.1 - 0.00018 21.2 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KLO10667.1 - 0.00035 20.8 0.0 0.00056 20.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KLO10667.1 - 0.00078 19.1 0.0 0.0015 18.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO10667.1 - 0.001 19.5 0.1 0.0014 19.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.6 KLO10667.1 - 0.003 17.8 0.1 0.017 15.3 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 KLO10667.1 - 0.0033 16.6 0.1 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.15 KLO10667.1 - 0.0096 15.9 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KLO10667.1 - 0.011 15.5 0.0 0.057 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KLO10667.1 - 0.014 15.4 0.1 0.054 13.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KLO10667.1 - 0.018 15.6 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KLO10667.1 - 0.06 13.4 0.0 0.079 13.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KLO10667.1 - 0.064 13.0 0.1 0.14 11.9 0.1 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_ATPase PF09818.9 KLO10667.1 - 0.066 12.0 0.1 4.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 KLO10667.1 - 0.066 13.8 0.1 0.15 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KLO10667.1 - 0.071 13.3 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KLO10667.1 - 0.085 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KLO10667.1 - 0.12 12.7 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KLO10667.1 - 0.15 12.5 0.2 0.53 10.7 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PI3_PI4_kinase PF00454.27 KLO10668.1 - 5.6e-37 127.9 0.1 5.9e-36 124.6 0.1 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KLO10668.1 - 0.0064 16.4 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 TRAPPC9-Trs120 PF08626.11 KLO10669.1 - 4.3e-192 640.5 0.0 5e-190 633.7 0.0 2.0 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 KLO10669.1 - 0.094 13.0 0.0 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps55 PF04133.14 KLO10670.1 - 4.4e-43 146.0 5.6 4.9e-43 145.8 5.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2933 PF11666.8 KLO10670.1 - 0.089 12.8 1.8 0.18 11.9 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) Elf1 PF05129.13 KLO10671.1 - 1.5e-23 82.6 0.7 1.7e-23 82.4 0.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-DBF PF07535.12 KLO10671.1 - 0.056 13.6 0.3 0.082 13.0 0.3 1.2 1 0 0 1 1 1 0 DBF zinc finger YceD PF02620.17 KLO10671.1 - 0.088 12.9 0.1 0.14 12.3 0.1 1.4 1 1 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD Kinesin PF00225.23 KLO10672.1 - 3.8e-107 358.1 0.9 6.2e-107 357.4 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KLO10672.1 - 2e-22 79.8 0.0 2e-22 79.8 0.0 3.0 5 0 0 5 5 5 1 Microtubule binding Microtub_bind PF13931.6 KLO10672.1 - 8.4e-08 32.7 0.8 8.4e-08 32.7 0.8 5.3 4 2 0 4 4 4 1 Kinesin-associated microtubule-binding DUF4200 PF13863.6 KLO10672.1 - 0.013 15.9 4.0 0.013 15.9 4.0 6.5 3 3 4 7 7 7 0 Domain of unknown function (DUF4200) HisKA PF00512.25 KLO10672.1 - 0.05 13.6 10.9 4.3 7.5 0.2 4.9 5 0 0 5 5 5 0 His Kinase A (phospho-acceptor) domain AKNA PF12443.8 KLO10672.1 - 0.11 13.2 0.1 0.11 13.2 0.1 4.3 4 0 0 4 4 4 0 AT-hook-containing transcription factor Metal_resist PF13801.6 KLO10672.1 - 6.1 7.1 7.8 15 5.8 4.1 3.0 2 0 0 2 2 2 0 Heavy-metal resistance Kinesin PF00225.23 KLO10673.1 - 5.2e-112 374.0 0.1 5.2e-112 374.0 0.1 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KLO10673.1 - 8.5e-28 97.2 0.0 3.6e-27 95.1 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding DUF465 PF04325.13 KLO10673.1 - 1.5e-07 31.3 1.9 1.5e-07 31.3 1.9 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF465) Vta1_C PF18097.1 KLO10673.1 - 0.052 13.3 0.0 0.26 11.0 0.0 2.2 1 0 0 1 1 1 0 Vta1 C-terminal domain RhlB PF12300.8 KLO10674.1 - 0.39 10.8 8.9 0.7 10.0 8.9 1.4 1 1 0 1 1 1 0 ATP-dependent RNA helicase RhlB PUF PF00806.19 KLO10675.1 - 1.5e-59 194.4 4.9 2.7e-08 33.1 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 KLO10675.1 - 0.0042 16.9 0.0 12 5.8 0.0 4.2 5 0 0 5 5 5 1 Single Cache domain 2 DUF445 PF04286.12 KLO10675.1 - 0.04 13.7 0.1 2.1 8.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF3683 PF12447.8 KLO10675.1 - 0.074 13.2 1.6 0.37 10.9 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3683) RisS_PPD PF16524.5 KLO10675.1 - 0.2 11.9 0.3 4.9 7.4 0.0 2.8 3 0 0 3 3 3 0 Periplasmic domain of Sensor histidine kinase RisS Sec16_C PF12931.7 KLO10677.1 - 3.4e-96 322.5 0.0 4.7e-96 322.0 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KLO10677.1 - 3.9e-28 98.4 0.7 7.2e-27 94.3 0.0 2.5 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region OST3_OST6 PF04756.13 KLO10678.1 - 2.2e-83 280.0 0.4 2.6e-83 279.8 0.4 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KLO10678.1 - 0.0025 17.8 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin C1_1 PF00130.22 KLO10679.1 - 4.7e-07 29.6 14.1 6e-07 29.2 0.8 2.6 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KLO10679.1 - 0.00023 21.4 12.5 0.035 14.4 1.1 2.5 2 0 0 2 2 2 2 C1 domain UNC-79 PF14776.6 KLO10679.1 - 0.0026 16.6 0.1 0.0042 15.9 0.1 1.2 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 Zn_ribbon_17 PF17120.5 KLO10679.1 - 0.47 10.1 12.4 2.6 7.7 4.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type SRRM_C PF15230.6 KLO10679.1 - 1.9 9.1 6.4 7.3 7.2 6.4 2.0 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus PHD PF00628.29 KLO10679.1 - 3.8 7.5 15.1 3 7.8 0.9 2.4 2 0 0 2 2 2 0 PHD-finger Pkinase_fungal PF17667.1 KLO10681.1 - 1.1e-91 307.6 2.1 7.8e-91 304.9 2.1 2.0 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO10681.1 - 5.2e-10 39.1 1.1 1.3e-09 37.8 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KLO10681.1 - 0.00015 21.2 0.3 0.00051 19.5 0.2 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KLO10681.1 - 0.00077 18.8 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KLO10681.1 - 0.0066 16.1 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KLO10681.1 - 0.051 13.5 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CTP-dep_RFKase PF01982.16 KLO10681.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF120 RIO1 PF01163.22 KLO10681.1 - 0.067 12.8 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KLO10682.1 - 3e-27 95.4 0.1 3.8e-27 95.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO10682.1 - 0.0046 16.3 0.1 0.011 15.1 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KLO10682.1 - 0.07 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_fungal PF17667.1 KLO10683.1 - 2.1e-24 86.1 0.0 2.9e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO10683.1 - 1.5e-05 24.5 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KLO10683.1 - 1.8e-05 24.2 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO10683.1 - 0.0013 18.7 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KLO10683.1 - 0.0069 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NOC3p PF07540.11 KLO10684.1 - 1.5e-32 111.9 0.0 4.4e-32 110.4 0.0 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 KLO10684.1 - 7.4e-21 74.9 0.1 9.1e-19 68.1 0.0 2.7 2 0 0 2 2 2 1 CBF/Mak21 family HisKA_2 PF07568.12 KLO10684.1 - 0.049 13.7 0.0 0.2 11.8 0.0 2.1 1 0 0 1 1 1 0 Histidine kinase DUF4337 PF14235.6 KLO10684.1 - 0.77 9.9 4.2 2.6 8.1 4.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Neur_chan_memb PF02932.16 KLO10684.1 - 8.2 6.4 6.3 8.5 6.4 0.2 2.9 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region ANAPC5 PF12862.7 KLO10685.1 - 9.5e-10 38.4 0.3 5.9e-09 35.9 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 KLO10685.1 - 0.068 13.1 0.2 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO10685.1 - 0.084 12.2 5.3 0.042 13.2 1.0 2.3 2 1 0 2 2 2 0 MalT-like TPR region Methyltransf_3 PF01596.17 KLO10686.1 - 6e-34 117.1 0.2 6.2e-34 117.0 0.2 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KLO10686.1 - 6.9e-16 59.2 0.0 9.6e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO10686.1 - 4.7e-10 39.5 0.0 6.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO10686.1 - 1.3e-07 32.2 0.0 1.8e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO10686.1 - 4.4e-07 30.5 0.0 1.1e-06 29.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KLO10686.1 - 3.8e-06 26.7 0.0 4.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 KLO10686.1 - 4e-06 26.7 0.0 5.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KLO10686.1 - 0.00015 21.2 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 KLO10686.1 - 0.0099 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 KLO10686.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 KLO10686.1 - 0.028 13.7 0.0 0.041 13.2 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltr_RsmB-F PF01189.17 KLO10686.1 - 0.049 13.3 0.0 0.087 12.4 0.0 1.4 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F CmcI PF04989.12 KLO10686.1 - 0.049 13.3 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Dala_Dala_lig_N PF01820.21 KLO10686.1 - 0.069 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DSBA PF01323.20 KLO10687.1 - 0.025 14.4 0.1 0.04 13.7 0.1 1.4 1 1 0 1 1 1 0 DSBA-like thioredoxin domain TPR_12 PF13424.6 KLO10688.1 - 5.3e-15 55.5 20.0 0.0018 18.5 0.1 7.0 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO10688.1 - 7.4e-12 45.3 17.6 9.2e-10 38.4 5.3 4.1 3 1 1 4 4 4 2 MalT-like TPR region TPR_2 PF07719.17 KLO10688.1 - 1.9e-10 40.0 10.5 0.58 10.4 0.1 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat AAA_22 PF13401.6 KLO10688.1 - 7.4e-08 32.8 0.9 1.9e-06 28.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain TPR_7 PF13176.6 KLO10688.1 - 1.3e-07 31.1 14.4 0.29 11.2 1.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat NB-ARC PF00931.22 KLO10688.1 - 1.9e-07 30.5 0.0 3.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.28 KLO10688.1 - 5.9e-05 22.7 11.9 0.77 9.7 0.3 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat NACHT PF05729.12 KLO10688.1 - 6.1e-05 23.0 0.6 0.00032 20.7 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KLO10688.1 - 0.00025 21.5 0.1 0.0062 16.9 0.1 2.9 1 1 0 1 1 1 1 AAA ATPase domain ANAPC3 PF12895.7 KLO10688.1 - 0.00053 20.2 2.5 14 6.0 0.2 4.4 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KLO10688.1 - 0.0015 18.3 20.9 0.61 10.0 0.6 8.9 10 0 0 10 10 10 1 Tetratricopeptide repeat ATPase_2 PF01637.18 KLO10688.1 - 0.0034 17.3 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_8 PF13181.6 KLO10688.1 - 0.0037 17.3 7.4 51 4.5 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA PF00004.29 KLO10688.1 - 0.083 13.3 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) TPR_16 PF13432.6 KLO10688.1 - 0.59 10.8 0.0 0.59 10.8 0.0 6.3 7 2 0 7 7 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KLO10688.1 - 2.6 8.2 6.3 9.7 6.3 0.4 4.0 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 KLO10688.1 - 4.2 8.5 28.1 4.8 8.3 0.1 8.4 9 1 1 10 10 8 0 Tetratricopeptide repeat DUF2201_N PF13203.6 KLO10689.1 - 6.2 6.3 9.8 1.1 8.8 0.1 3.1 3 0 0 3 3 3 0 Putative metallopeptidase domain zf-C3HC4_3 PF13920.6 KLO10690.1 - 0.021 14.7 8.4 0.035 14.0 8.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FliO PF04347.13 KLO10690.1 - 0.031 14.6 0.4 0.1 12.9 0.4 2.0 1 1 0 1 1 1 0 Flagellar biosynthesis protein, FliO Zn-C2H2_12 PF18112.1 KLO10690.1 - 0.17 12.4 0.5 0.38 11.3 0.5 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain DUF3886 PF13025.6 KLO10690.1 - 0.54 10.5 6.7 3.5 7.9 4.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) E1-E2_ATPase PF00122.20 KLO10691.1 - 1.8e-52 177.5 6.5 1.2e-51 174.8 2.9 2.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KLO10691.1 - 7.3e-46 156.2 8.2 7.3e-46 156.2 8.2 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KLO10691.1 - 1.9e-21 75.5 0.4 6.7e-21 73.8 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KLO10691.1 - 4.9e-21 76.0 3.8 6e-20 72.4 1.2 3.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KLO10691.1 - 2.7e-20 72.3 0.0 5e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KLO10691.1 - 8.5e-08 32.2 1.0 4.1e-06 26.7 1.2 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KLO10691.1 - 6.8e-07 29.9 0.0 1.7e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DPBB_1 PF03330.18 KLO10692.1 - 4.5e-07 30.1 0.0 4.9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KLO10692.1 - 0.041 13.7 0.0 0.055 13.3 0.0 1.3 1 1 0 1 1 1 0 Barwin family RRM_1 PF00076.22 KLO10693.1 - 1.3e-26 92.2 0.0 2.6e-13 49.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 KLO10693.1 - 8.1e-23 78.8 0.0 4.3e-05 23.0 0.0 5.9 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 KLO10693.1 - 2.4e-06 27.3 0.0 0.053 13.4 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 KLO10693.1 - 0.048 13.1 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA-recognition motif ThrE PF06738.12 KLO10694.1 - 2.4e-42 145.0 16.9 1.9e-41 142.1 3.9 2.9 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KLO10694.1 - 4.6e-10 39.7 20.2 1.4e-06 28.5 3.9 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Pkinase_fungal PF17667.1 KLO10695.1 - 1.3e-69 234.9 0.1 4.2e-69 233.3 0.1 1.7 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO10695.1 - 5.1e-09 35.9 0.1 2.8e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KLO10695.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KLO10695.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KLO10695.1 - 0.022 14.4 0.0 0.07 12.7 0.0 1.8 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KLO10696.1 - 8.8e-34 117.0 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO10696.1 - 3.4e-06 26.6 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KLO10696.1 - 0.00032 20.1 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KLO10696.1 - 0.0019 17.5 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO10697.1 - 7.7e-81 271.9 0.1 8.5e-80 268.5 0.1 2.1 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO10697.1 - 1.2e-09 38.0 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO10697.1 - 0.0004 19.7 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KLO10697.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CBP4 PF07960.11 KLO10698.1 - 1.2e-05 25.1 1.5 2.1e-05 24.3 1.5 1.4 1 1 0 1 1 1 1 CBP4 DUF1682 PF07946.14 KLO10698.1 - 0.063 12.5 0.6 0.061 12.5 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Med3 PF11593.8 KLO10698.1 - 0.37 9.9 6.7 0.38 9.9 6.7 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TPT PF03151.16 KLO10699.1 - 6.2e-08 32.3 6.8 1.3e-05 24.7 0.8 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KLO10699.1 - 1.4e-06 28.5 29.0 0.00015 22.0 4.8 3.0 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KLO10699.1 - 3e-06 26.6 0.5 3e-06 26.6 0.5 1.5 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.11 KLO10699.1 - 3.4e-05 23.2 5.7 5.4e-05 22.5 5.7 1.2 1 0 0 1 1 1 1 UAA transporter family CPP1-like PF11833.8 KLO10699.1 - 7 6.2 7.7 0.17 11.6 0.8 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DPBB_1 PF03330.18 KLO10703.1 - 0.00016 21.9 0.0 0.00045 20.4 0.0 1.8 2 0 0 2 2 2 1 Lytic transglycolase FliD_N PF02465.18 KLO10703.1 - 1.5 9.6 9.6 16 6.3 10.3 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SOG2 PF10428.9 KLO10703.1 - 4.4 6.4 17.5 5.9 6.0 17.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein F-box-like PF12937.7 KLO10704.1 - 0.00017 21.4 0.8 0.00085 19.2 0.8 2.2 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO10705.1 - 0.11 13.0 5.5 0.23 11.9 0.5 3.8 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) Spc24 PF08286.11 KLO10706.1 - 1.5e-15 57.3 0.0 5.7e-15 55.4 0.0 1.8 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF1845 PF08900.11 KLO10706.1 - 0.064 13.0 0.1 0.12 12.1 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1845) Cauli_DNA-bind PF03310.13 KLO10706.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 1 0 1 1 1 0 Caulimovirus DNA-binding protein CAF1A PF12253.8 KLO10707.1 - 2.4e-21 75.7 1.8 2.4e-21 75.7 1.8 2.2 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A AAA PF00004.29 KLO10708.1 - 4.5e-15 56.2 0.0 1e-14 55.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KLO10708.1 - 4.3e-12 46.1 0.0 1.6e-10 41.0 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KLO10708.1 - 6.6e-11 42.5 0.0 1.9e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 KLO10708.1 - 1.1e-07 32.0 0.0 3.4e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KLO10708.1 - 1e-05 25.8 0.0 3.7e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO10708.1 - 1.2e-05 25.8 0.0 0.00019 21.9 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 KLO10708.1 - 5.8e-05 23.0 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KLO10708.1 - 0.00014 22.1 0.0 0.00039 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 KLO10708.1 - 0.00024 20.9 0.0 0.00057 19.7 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KLO10708.1 - 0.0006 19.6 0.0 0.0026 17.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KLO10708.1 - 0.00087 19.3 0.0 0.0034 17.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KLO10708.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KLO10708.1 - 0.0021 17.6 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KLO10708.1 - 0.0028 17.1 0.0 0.088 12.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KLO10708.1 - 0.0055 17.0 0.0 0.039 14.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KLO10708.1 - 0.0069 16.4 0.0 0.04 13.9 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KLO10708.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.14 KLO10708.1 - 0.03 14.5 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KLO10708.1 - 0.03 13.5 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.13 KLO10708.1 - 0.034 13.9 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DEAD PF00270.29 KLO10708.1 - 0.044 13.5 0.1 0.26 11.0 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase DUF5338 PF17273.2 KLO10708.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5338) AAA_23 PF13476.6 KLO10708.1 - 0.053 14.0 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KLO10708.1 - 0.071 13.7 0.0 0.19 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KLO10708.1 - 0.08 13.2 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sec3_C_2 PF15278.6 KLO10708.1 - 0.11 12.9 0.1 0.49 10.8 0.0 2.1 2 0 0 2 2 2 0 Sec3 exocyst complex subunit HSP70 PF00012.20 KLO10709.1 - 1.4e-233 776.5 10.5 1.7e-233 776.2 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KLO10709.1 - 4.3e-18 65.2 0.4 4.6e-17 61.8 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KLO10709.1 - 0.0021 17.8 0.0 0.0057 16.4 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KLO10709.1 - 0.0084 15.6 1.2 0.49 9.8 0.0 3.0 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family DUF1464 PF07318.12 KLO10709.1 - 0.21 10.7 0.0 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) Ribosomal_S2 PF00318.20 KLO10710.1 - 3.7e-52 176.7 0.0 2.4e-28 98.8 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 Pkinase_fungal PF17667.1 KLO10711.1 - 9.6e-15 54.3 0.0 1.1e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase 2OG-FeII_Oxy_3 PF13640.6 KLO10713.1 - 2e-08 35.0 0.0 3e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KLO10714.1 - 1.1e-07 32.7 0.0 2.5e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Chorismate_bind PF00425.18 KLO10715.1 - 2.3e-89 299.4 0.0 3.5e-89 298.8 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KLO10715.1 - 8.2e-23 81.2 0.0 8.4e-22 77.9 0.0 2.7 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region SHQ1 PF04925.15 KLO10716.1 - 2.5e-54 183.5 0.0 5.1e-54 182.5 0.0 1.5 2 0 0 2 2 2 1 SHQ1 protein PIH1_CS PF18201.1 KLO10716.1 - 0.00031 21.1 0.0 0.00062 20.1 0.0 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain CS PF04969.16 KLO10716.1 - 0.00042 21.3 0.0 0.001 20.0 0.0 1.7 1 0 0 1 1 1 1 CS domain Acetyltransf_15 PF17013.5 KLO10716.1 - 0.18 11.2 0.1 0.46 9.9 0.1 1.7 1 0 0 1 1 1 0 Putative acetyl-transferase Pkinase_fungal PF17667.1 KLO10717.1 - 3.6e-69 233.5 0.0 2e-68 231.0 0.0 2.1 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 KLO10717.1 - 0.00039 19.9 0.2 0.0025 17.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO10717.1 - 0.038 13.3 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase HRG PF16954.5 KLO10721.1 - 0.23 11.9 0.2 0.23 11.9 0.2 3.0 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene adh_short PF00106.25 KLO10723.1 - 4.4e-20 72.0 0.2 7e-20 71.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO10723.1 - 2.3e-13 50.2 0.1 3.3e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO10723.1 - 0.0057 16.6 0.1 0.013 15.5 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KLO10723.1 - 0.0098 15.4 0.1 0.063 12.7 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KLO10723.1 - 0.059 13.3 1.7 0.13 12.1 0.6 2.0 2 1 0 2 2 2 0 NAD(P)H-binding Aldo_ket_red PF00248.21 KLO10724.1 - 3.6e-67 226.6 0.0 4.2e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LppA PF16708.5 KLO10724.1 - 0.16 11.9 0.1 0.53 10.2 0.0 1.8 2 0 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium Aldo_ket_red PF00248.21 KLO10725.1 - 1.2e-70 238.1 0.0 1.5e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PQ-loop PF04193.14 KLO10726.1 - 2.5e-38 129.7 6.9 1.3e-19 69.7 0.7 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 KLO10726.1 - 0.097 12.7 0.4 0.097 12.7 0.4 2.0 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange p450 PF00067.22 KLO10727.1 - 1e-69 235.5 0.0 1.3e-69 235.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nuc_sug_transp PF04142.15 KLO10728.1 - 9.3e-95 317.4 11.9 2.3e-83 280.0 8.4 2.0 2 0 0 2 2 2 2 Nucleotide-sugar transporter CRT-like PF08627.10 KLO10728.1 - 0.0048 15.9 0.3 0.0048 15.9 0.3 1.8 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KLO10728.1 - 0.008 16.4 0.8 0.008 16.4 0.8 2.8 3 0 0 3 3 3 1 EamA-like transporter family UAA PF08449.11 KLO10728.1 - 0.014 14.7 8.6 0.026 13.7 8.6 1.5 1 1 0 1 1 1 0 UAA transporter family TPT PF03151.16 KLO10728.1 - 0.017 14.5 9.8 0.15 11.4 0.4 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family HhH-GPD PF00730.25 KLO10729.1 - 3.3e-19 69.3 0.0 7.7e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KLO10729.1 - 2.6e-12 46.7 0.1 5.2e-11 42.5 0.1 2.6 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.23 KLO10729.1 - 3.6e-06 26.6 0.1 1.4e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KLO10729.1 - 0.017 15.4 3.8 0.056 13.8 3.8 2.0 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Aldo_ket_red PF00248.21 KLO10730.1 - 3e-68 230.2 0.0 4e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 KLO10731.1 - 3.7e-20 72.2 0.1 5e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO10731.1 - 1.2e-14 54.5 0.0 1.6e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO10731.1 - 0.0027 17.7 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KLO10731.1 - 0.012 15.1 0.0 0.047 13.1 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KLO10731.1 - 0.022 14.3 0.4 0.04 13.5 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 KLO10731.1 - 0.026 14.4 0.2 0.04 13.8 0.2 1.5 1 1 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 KLO10732.1 - 4.1e-18 65.6 0.1 5.8e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO10732.1 - 7.1e-13 48.7 0.1 9.1e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO10733.1 - 1.7e-23 83.1 0.2 2.6e-23 82.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO10733.1 - 6.4e-18 65.2 0.1 8.5e-18 64.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO10733.1 - 6.9e-05 22.8 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KLO10733.1 - 0.00012 22.1 0.1 0.00024 21.0 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KLO10733.1 - 0.002 17.7 0.2 0.0032 17.1 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KLO10733.1 - 0.0079 15.7 0.0 3.8 6.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DHDPS PF00701.22 KLO10734.1 - 9.4e-28 96.7 0.0 3.6e-27 94.8 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Pkinase_fungal PF17667.1 KLO10735.1 - 5.9e-24 84.6 0.1 8.2e-24 84.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase TruB_N PF01509.18 KLO10736.1 - 1.3e-43 148.9 0.0 3e-43 147.7 0.0 1.6 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KLO10736.1 - 8e-05 22.7 0.0 0.00024 21.2 0.0 1.9 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Aldo_ket_red PF00248.21 KLO10737.1 - 2.4e-64 217.4 0.0 3e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family O-FucT PF10250.9 KLO10737.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase NAD_binding_6 PF08030.12 KLO10739.1 - 5.5e-16 59.1 0.1 1.2e-15 58.0 0.1 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KLO10739.1 - 7.7e-13 48.7 7.6 7.7e-13 48.7 7.6 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KLO10739.1 - 2.9e-11 43.4 0.0 5.4e-10 39.3 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain AzlD PF05437.12 KLO10739.1 - 0.047 13.9 1.1 0.17 12.1 1.1 1.9 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) PRMT5 PF05185.16 KLO10739.1 - 0.2 11.5 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Epimerase PF01370.21 KLO10740.1 - 1.4e-20 73.8 0.2 2.8e-20 72.8 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO10740.1 - 6.9e-16 58.1 0.1 5.1e-15 55.2 0.1 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KLO10740.1 - 7.9e-16 58.5 1.0 7.9e-16 58.5 1.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KLO10740.1 - 1.8e-10 40.8 0.9 3.3e-09 36.6 0.8 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 KLO10740.1 - 2.8e-08 33.2 0.1 0.00027 20.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KLO10740.1 - 3.1e-07 30.1 0.2 8.3e-07 28.7 0.2 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KLO10740.1 - 3.2e-06 26.5 0.4 5.9e-06 25.6 0.4 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Mur_ligase PF01225.25 KLO10740.1 - 0.0045 17.3 0.1 1.4 9.3 0.0 2.5 1 1 1 2 2 2 2 Mur ligase family, catalytic domain adh_short PF00106.25 KLO10740.1 - 0.035 13.6 2.5 2.2 7.7 2.5 3.1 1 1 0 1 1 1 0 short chain dehydrogenase Ferritin_2 PF13668.6 KLO10742.1 - 3e-40 137.6 1.7 4.5e-40 137.0 1.7 1.3 1 0 0 1 1 1 1 Ferritin-like domain SKG6 PF08693.10 KLO10743.1 - 0.0025 17.2 0.2 0.0054 16.1 0.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mucin15 PF15672.5 KLO10743.1 - 0.0027 17.3 0.1 0.0039 16.7 0.1 1.2 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 MGC-24 PF05283.11 KLO10743.1 - 0.0029 18.0 3.1 0.0064 16.9 3.1 1.5 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Amnionless PF14828.6 KLO10743.1 - 0.022 13.6 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF4064 PF13273.6 KLO10743.1 - 0.07 13.4 0.4 0.16 12.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Beta-APP PF03494.13 KLO10743.1 - 0.097 12.5 2.0 0.19 11.6 2.0 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) VPDSG-CTERM PF18205.1 KLO10743.1 - 2.5 8.0 12.7 2 8.3 2.5 2.5 2 0 0 2 2 2 0 VPDSG-CTERM motif Phage_Coat_B PF05356.11 KLO10743.1 - 2.8 7.9 5.0 4 7.4 2.3 2.5 1 1 1 2 2 2 0 Phage Coat protein B SKG6 PF08693.10 KLO10744.1 - 0.029 13.8 0.6 0.029 13.8 0.6 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain TrbC PF04956.13 KLO10746.1 - 0.13 12.5 0.5 5.4 7.3 0.0 2.7 3 0 0 3 3 3 0 TrbC/VIRB2 family Protocadherin PF08374.11 KLO10747.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Protocadherin TNFR_16_TM PF18422.1 KLO10747.1 - 0.093 12.7 0.4 0.2 11.6 0.4 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain EphA2_TM PF14575.6 KLO10747.1 - 0.1 13.5 0.0 0.19 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Miga PF10265.9 KLO10747.1 - 3.5 6.5 4.7 2.5 7.0 0.0 2.0 1 1 1 2 2 2 0 Mitoguardin LPG_synthase_TM PF03706.13 KLO10748.1 - 0.0056 16.3 0.2 0.01 15.4 0.2 1.3 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region Adeno_E3_CR2 PF02439.15 KLO10748.1 - 0.062 13.1 0.8 0.11 12.3 0.8 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4381 PF14316.6 KLO10748.1 - 0.082 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 KLO10748.1 - 0.1 13.5 0.0 0.22 12.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 KLO10748.1 - 0.13 12.0 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF5305 PF17231.2 KLO10748.1 - 0.14 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SDF PF00375.18 KLO10748.1 - 0.64 9.0 6.7 0.99 8.3 6.7 1.2 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family UPF0016 PF01169.19 KLO10748.1 - 0.67 10.3 3.0 0.87 10.0 1.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 TMEM154 PF15102.6 KLO10748.1 - 1.9 8.4 8.9 33 4.4 8.1 2.5 1 1 0 1 1 1 0 TMEM154 protein family Ribosomal_L30_N PF08079.12 KLO10749.1 - 4.5e-26 90.9 18.4 4.5e-26 90.9 18.4 1.7 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KLO10749.1 - 2.9e-19 68.7 2.3 3.3e-19 68.5 0.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e CMD PF02627.20 KLO10751.1 - 7.6e-10 38.7 0.3 1.4e-08 34.6 0.1 2.1 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family CLTH PF10607.9 KLO10752.1 - 1.4e-15 57.5 0.0 2.6e-15 56.6 0.0 1.4 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KLO10752.1 - 7e-06 25.8 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 LisH PhnA_Zn_Ribbon PF08274.12 KLO10754.1 - 0.028 14.4 0.3 0.085 12.8 0.0 1.9 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Imm71 PF15602.6 KLO10754.1 - 0.041 13.9 0.0 0.063 13.3 0.0 1.6 1 1 0 1 1 1 0 Immunity protein 71 RtcB PF01139.17 KLO10755.1 - 2.1e-61 208.4 0.0 3.9e-50 171.2 0.0 2.5 2 1 0 2 2 2 2 tRNA-splicing ligase RtcB BTB PF00651.31 KLO10756.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain PNTB PF02233.16 KLO10757.1 - 9.8e-176 585.2 23.5 9.8e-176 585.2 23.5 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KLO10757.1 - 2.7e-69 232.7 0.2 1.2e-68 230.6 0.2 2.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KLO10757.1 - 1.9e-43 148.0 0.0 8.3e-43 145.9 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KLO10757.1 - 7.2e-31 106.5 5.0 7.2e-31 106.5 5.0 4.6 3 2 2 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KLO10757.1 - 0.00083 18.8 0.1 0.62 9.4 0.0 3.2 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KLO10757.1 - 0.012 14.9 0.3 0.035 13.3 0.3 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO10757.1 - 8.2 6.7 9.3 0.69 10.2 2.2 3.0 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain BTB PF00651.31 KLO10758.1 - 0.00028 21.1 0.0 0.0012 19.1 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 KLO10759.1 - 0.00024 21.0 1.1 0.00052 19.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO10759.1 - 0.015 15.1 0.4 0.015 15.1 0.4 2.2 2 0 0 2 2 2 0 F-box domain UvrD_C PF13361.6 KLO10759.1 - 0.029 13.8 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain LRR_8 PF13855.6 KLO10759.1 - 0.11 12.3 3.2 8.3 6.3 0.0 3.5 2 1 0 2 2 2 0 Leucine rich repeat F-box_4 PF15966.5 KLO10759.1 - 0.16 11.9 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 KLO10760.1 - 5.6e-05 22.9 0.3 0.00018 21.3 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO10760.1 - 0.0011 18.7 0.7 0.0037 17.1 0.7 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KLO10760.1 - 0.004 17.0 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 F-box LRR_8 PF13855.6 KLO10760.1 - 0.0051 16.5 13.8 0.29 10.9 1.0 5.7 6 0 0 6 6 6 2 Leucine rich repeat OHA PF14418.6 KLO10760.1 - 0.066 13.0 0.0 6.9 6.6 0.0 2.9 2 0 0 2 2 2 0 OST-HTH Associated domain RNA_polI_A14 PF08203.11 KLO10761.1 - 1.2 9.8 4.7 1.9 9.3 0.9 2.7 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Gluconate_2-dh3 PF13618.6 KLO10761.1 - 1.3 9.2 4.0 3.4 7.9 2.4 2.1 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 ERp29 PF07749.12 KLO10761.1 - 1.4 9.9 4.5 6.5 7.7 1.9 3.2 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain Big_7 PF17957.1 KLO10765.1 - 0.013 16.3 0.0 0.021 15.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig domain PASTA PF03793.19 KLO10765.1 - 0.05 13.5 0.1 0.091 12.6 0.1 1.4 1 0 0 1 1 1 0 PASTA domain DM PF00751.18 KLO10766.1 - 0.12 12.3 0.7 0.26 11.2 0.7 1.5 1 0 0 1 1 1 0 DM DNA binding domain PDH PF02153.17 KLO10768.1 - 6.5e-15 54.8 0.0 8.8e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KLO10768.1 - 2.9e-07 31.0 0.0 6.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KLO10768.1 - 9e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KLO10768.1 - 0.0018 18.3 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KLO10768.1 - 0.0099 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KLO10768.1 - 0.021 15.1 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 KLO10768.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KLO10768.1 - 0.13 12.1 0.1 0.32 10.8 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCR PF18509.1 KLO10768.1 - 0.17 11.5 0.6 0.34 10.5 0.6 1.5 1 0 0 1 1 1 0 Magnetochrome domain VIT1 PF01988.19 KLO10769.1 - 1.8 8.4 3.8 15 5.4 2.6 2.0 1 1 1 2 2 2 0 VIT family zf-MYND PF01753.18 KLO10771.1 - 2.8e-10 40.1 9.4 5.8e-10 39.1 9.4 1.5 1 0 0 1 1 1 1 MYND finger DUF3700 PF12481.8 KLO10771.1 - 0.17 11.3 0.1 0.48 9.8 0.0 1.7 2 0 0 2 2 2 0 Aluminium induced protein TTRAP PF14203.6 KLO10771.1 - 0.31 11.1 1.1 0.73 9.9 1.1 1.6 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein RecR PF02132.15 KLO10771.1 - 1.6 8.4 5.5 1.7 8.3 3.1 2.4 2 0 0 2 2 2 0 RecR protein zf-MYND PF01753.18 KLO10772.1 - 1.9e-11 43.9 11.7 4.2e-11 42.7 11.7 1.6 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 KLO10772.1 - 0.0077 16.6 5.5 0.022 15.1 5.5 1.8 1 0 0 1 1 1 1 Rhodanase C-terminal PHF5 PF03660.14 KLO10772.1 - 5.2 7.3 9.4 0.37 11.0 4.2 1.7 2 0 0 2 2 2 0 PHF5-like protein TPT PF03151.16 KLO10773.1 - 2.1e-38 132.4 11.9 3.3e-26 92.3 6.4 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 KLO10773.1 - 1.9e-09 37.2 10.5 2.6e-06 26.9 2.2 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 KLO10773.1 - 1.6e-07 31.5 27.9 0.00059 20.0 10.1 3.1 3 0 0 3 3 3 2 EamA-like transporter family Trep_Strep PF09605.10 KLO10773.1 - 0.0031 17.5 8.4 0.0031 17.5 8.4 2.3 2 0 0 2 2 2 1 Hypothetical bacterial integral membrane protein (Trep_Strep) F-box-like PF12937.7 KLO10774.1 - 1.5e-06 28.0 0.6 1.5e-06 28.0 0.6 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO10774.1 - 1.4 8.9 11.6 5.8 6.9 0.1 4.1 4 0 0 4 4 4 0 F-box domain F-box-like PF12937.7 KLO10775.1 - 3.6e-06 26.8 4.0 3.6e-05 23.6 4.3 2.6 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO10775.1 - 0.058 13.9 4.3 12 6.5 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) zf-MYND PF01753.18 KLO10780.1 - 2e-05 24.6 12.0 4.4e-05 23.5 12.0 1.6 1 0 0 1 1 1 1 MYND finger DUF2256 PF10013.9 KLO10780.1 - 0.94 9.7 7.3 3 8.1 7.3 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) F-box-like PF12937.7 KLO10781.1 - 5.5e-05 23.0 3.5 0.00018 21.3 3.5 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO10781.1 - 0.016 15.1 2.4 0.16 11.9 1.6 2.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO10782.1 - 2.8e-05 23.9 4.8 2.8e-05 23.9 4.8 2.5 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO10783.1 - 7.8e-06 25.7 1.3 1.9e-05 24.4 0.3 2.3 2 0 0 2 2 2 1 F-box-like Mce4_CUP1 PF11887.8 KLO10783.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative zf-MYND PF01753.18 KLO10784.1 - 2.5e-10 40.3 10.8 5.5e-10 39.2 10.8 1.6 1 0 0 1 1 1 1 MYND finger RNase_II_C_S1 PF18614.1 KLO10785.1 - 0.093 12.7 0.7 0.15 12.0 0.5 1.4 1 1 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain ARA70 PF12489.8 KLO10790.1 - 0.055 13.7 0.9 0.12 12.6 0.4 1.6 1 1 0 1 1 1 0 Nuclear coactivator Big_3_3 PF13750.6 KLO10792.1 - 0.19 11.4 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Ricin_B_lectin PF00652.22 KLO10795.1 - 1.1e-19 70.9 6.4 1.1e-19 70.9 6.4 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KLO10795.1 - 5.2e-15 55.9 20.9 5.8e-07 30.1 1.9 2.8 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Crisp PF08562.10 KLO10795.1 - 3.1 8.4 5.8 0.82 10.3 0.9 2.4 2 0 0 2 2 2 0 Crisp zf-MYND PF01753.18 KLO10796.1 - 3.6e-07 30.2 7.7 7.1e-07 29.2 7.7 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO10796.1 - 0.15 12.1 5.6 0.25 11.5 3.5 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 F-box-like PF12937.7 KLO10797.1 - 3.3e-06 26.9 1.3 1.2e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO10797.1 - 0.02 15.3 15.1 0.04 14.4 0.9 4.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO10798.1 - 0.00011 22.0 3.8 0.00011 22.0 3.8 2.9 3 1 0 3 3 3 1 F-box-like DUF1033 PF06279.11 KLO10799.1 - 0.018 15.2 0.3 0.038 14.2 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1033) zf-MYND PF01753.18 KLO10800.1 - 5.2e-06 26.4 11.1 1.4e-05 25.1 11.1 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO10801.1 - 9.2e-08 32.1 11.2 1.7e-07 31.2 11.2 1.5 1 0 0 1 1 1 1 MYND finger Hypoth_Ymh PF09509.10 KLO10801.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) zf-MYND PF01753.18 KLO10802.1 - 8.9e-07 28.9 3.1 1.9e-06 27.8 3.1 1.6 1 0 0 1 1 1 1 MYND finger C1_1 PF00130.22 KLO10802.1 - 1 9.3 5.3 0.6 10.0 1.7 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) p450 PF00067.22 KLO10803.1 - 1.1e-49 169.5 0.0 1.3e-49 169.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO10805.1 - 0.00086 18.2 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO10806.1 - 1.9e-59 201.6 0.0 2.5e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO10807.1 - 6.3e-08 31.8 0.0 7.7e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2385 PF09539.10 KLO10807.1 - 0.1 13.1 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) Cdh1_DBD_1 PF18196.1 KLO10811.1 - 0.23 11.8 0.0 0.35 11.2 0.0 1.2 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 YL1 PF05764.13 KLO10813.1 - 0.0081 16.3 4.0 0.0081 16.3 4.0 2.2 2 0 0 2 2 2 1 YL1 nuclear protein GEN1_C PF18380.1 KLO10813.1 - 0.29 12.0 0.1 0.29 12.0 0.1 3.5 3 1 0 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain DUF702 PF05142.12 KLO10813.1 - 0.42 11.1 2.2 0.93 10.0 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Cation_ATPase_C PF00689.21 KLO10815.1 - 4.8e-46 156.7 4.3 4.8e-46 156.7 4.3 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KLO10815.1 - 1.2e-40 138.9 0.4 1.2e-40 138.9 0.4 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KLO10815.1 - 7.4e-22 77.3 0.0 1.4e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KLO10815.1 - 8.9e-17 62.1 0.2 1.7e-15 57.9 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KLO10815.1 - 6.1e-07 29.0 0.0 6.1e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KLO10815.1 - 0.00021 21.1 0.8 0.028 14.2 0.6 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Pam17 PF08566.10 KLO10815.1 - 0.051 13.4 0.1 4.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Herpes_IR6 PF06307.12 KLO10817.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus IR6 protein DUF3450 PF11932.8 KLO10821.1 - 0.01 15.1 0.1 0.014 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PEX11 PF05648.14 KLO10823.1 - 2.8e-13 49.9 0.1 1.1e-11 44.7 0.1 2.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FOXP-CC PF16159.5 KLO10824.1 - 0.00012 22.7 4.1 0.038 14.6 0.6 2.6 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 KLO10824.1 - 0.2 11.5 0.7 7.7 6.4 0.5 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 KLO10824.1 - 5.2 7.7 14.7 3.3 8.4 1.6 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Glyco_hydro_10 PF00331.20 KLO10825.1 - 6.2e-105 350.8 0.0 7.2e-105 350.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KLO10825.1 - 1e-14 54.2 9.7 1e-14 54.2 9.7 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain Cas9_PI2 PF18070.1 KLO10825.1 - 0.01 16.5 0.0 0.032 14.9 0.0 1.8 2 0 0 2 2 2 0 CRISPR-Cas9 PI domain Glyco_hydro_42 PF02449.15 KLO10825.1 - 0.033 13.5 0.0 0.076 12.3 0.0 1.6 1 1 1 2 2 2 0 Beta-galactosidase YqgF PF14639.6 KLO10825.1 - 0.2 11.5 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Ecl1 PF12855.7 KLO10827.1 - 4 8.6 18.8 6.3 7.9 18.8 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Tubulin PF00091.25 KLO10828.1 - 2.3e-64 217.3 0.0 3.6e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KLO10828.1 - 1.2e-39 135.4 0.0 1.9e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KLO10828.1 - 2.1e-05 24.8 0.2 5.3e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KLO10828.1 - 0.16 11.2 0.0 0.44 9.7 0.0 1.7 2 0 0 2 2 2 0 Tubulin like DUF4078 PF13300.6 KLO10829.1 - 2.6e-18 66.1 5.4 2.6e-18 66.1 5.4 4.7 3 1 1 4 4 4 2 Domain of unknown function (DUF4078) Vps39_1 PF10366.9 KLO10830.1 - 1.7e-26 92.6 0.2 2.3e-25 88.9 0.0 3.1 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KLO10830.1 - 1e-19 71.0 0.9 1.8e-19 70.2 0.3 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KLO10830.1 - 5.1e-10 39.4 0.0 1.8e-09 37.7 0.0 1.9 2 1 0 2 2 2 1 CNH domain Clathrin PF00637.20 KLO10830.1 - 2.4e-08 34.0 0.0 0.00011 22.1 0.0 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_1 PF00515.28 KLO10830.1 - 0.031 14.1 0.9 33 4.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4240 PF14024.6 KLO10830.1 - 0.16 12.2 0.0 39 4.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) RRM_1 PF00076.22 KLO10832.1 - 0.0062 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RTX_C PF08339.10 KLO10832.1 - 0.027 14.5 0.2 0.04 14.0 0.2 1.2 1 0 0 1 1 1 0 RTX C-terminal domain SPT2 PF08243.11 KLO10833.1 - 2.9e-18 66.4 18.8 2.9e-18 66.4 18.8 4.2 3 1 0 3 3 3 2 SPT2 chromatin protein COesterase PF00135.28 KLO10834.1 - 1.9e-92 310.8 0.0 2.1e-92 310.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO10834.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 KLO10835.1 - 1.6e-86 291.2 0.0 2e-86 290.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO10835.1 - 0.0023 17.8 0.0 0.0054 16.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pkinase_Tyr PF07714.17 KLO10839.1 - 2.5e-76 256.4 0.0 2.1e-39 135.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KLO10839.1 - 4.6e-74 249.1 0.0 1.2e-43 149.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Zn_clus PF00172.18 KLO10839.1 - 1.3e-07 31.7 7.8 1.3e-07 31.7 7.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinase-like PF14531.6 KLO10839.1 - 7e-05 22.3 0.0 0.28 10.4 0.0 2.6 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 KLO10839.1 - 0.00014 21.3 0.0 0.046 13.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO10839.1 - 0.00056 19.9 0.0 0.31 10.9 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KLO10839.1 - 0.0017 18.0 0.0 2.7 7.6 0.0 3.1 3 0 0 3 3 3 2 RIO1 family Pkinase_fungal PF17667.1 KLO10839.1 - 0.019 13.7 0.0 0.37 9.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KLO10840.1 - 6.3e-79 264.9 0.0 8.7e-40 136.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KLO10840.1 - 8.2e-74 248.3 0.0 1.5e-43 149.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KLO10840.1 - 5.5e-08 32.5 0.0 0.0092 15.3 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KLO10840.1 - 2.8e-05 23.1 0.5 0.065 12.0 0.0 2.6 3 0 0 3 3 3 2 Fungal protein kinase RIO1 PF01163.22 KLO10840.1 - 5.5e-05 22.9 0.0 0.31 10.6 0.0 2.8 3 0 0 3 3 3 2 RIO1 family Zn_clus PF00172.18 KLO10840.1 - 0.00018 21.6 10.3 0.00018 21.6 10.3 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kdo PF06293.14 KLO10840.1 - 0.00032 20.1 0.0 0.39 10.0 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO10840.1 - 0.006 16.5 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KLO10841.1 - 1.8e-42 145.4 0.0 2.5e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO10841.1 - 3.2e-42 144.7 0.0 4.9e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KLO10841.1 - 1.4e-05 24.1 0.0 2.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO10841.1 - 5.7e-05 22.6 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO10841.1 - 0.014 15.0 0.4 0.041 13.5 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KLO10841.1 - 0.05 12.9 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 KLO10842.1 - 1.9e-05 24.5 1.4 4.8e-05 23.2 0.4 2.4 2 0 0 2 2 2 1 F-box-like PCM1_C PF15717.5 KLO10844.1 - 0.11 11.2 0.2 0.15 10.7 0.2 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus GMC_oxred_N PF00732.19 KLO10847.1 - 1.2e-53 182.4 0.0 1.8e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO10847.1 - 7e-32 110.9 0.0 1.3e-31 110.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Peptidase_Prp PF04327.12 KLO10847.1 - 0.18 12.1 0.0 0.73 10.1 0.0 1.9 2 0 0 2 2 2 0 Cysteine protease Prp ERAP1_C PF11838.8 KLO10848.1 - 3.5e-20 72.8 6.3 2.9e-12 46.8 1.2 2.8 1 1 2 3 3 3 2 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KLO10848.1 - 1.7e-18 67.5 0.3 8.2e-18 65.2 0.3 2.0 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain COX8 PF02285.15 KLO10848.1 - 0.0068 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIII Thiolase_N PF00108.23 KLO10849.1 - 4.3e-79 265.6 7.1 4.3e-79 265.6 7.1 1.9 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KLO10849.1 - 1.2e-43 147.7 0.7 3e-43 146.4 0.7 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KLO10849.1 - 0.0028 17.3 3.6 0.011 15.3 1.4 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain FTCD_C PF04961.12 KLO10849.1 - 0.79 9.5 6.6 0.89 9.3 3.0 2.4 2 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase Nab2p_Zf1 PF18260.1 KLO10853.1 - 0.089 12.7 1.7 0.24 11.4 0.1 2.4 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 CVNH PF08881.10 KLO10855.1 - 7.2e-20 71.6 0.8 1.3e-19 70.7 0.7 1.5 1 1 0 1 1 1 1 CVNH domain CVNH PF08881.10 KLO10857.1 - 2.4e-19 69.9 0.9 3e-19 69.6 0.9 1.1 1 0 0 1 1 1 1 CVNH domain Ricin_B_lectin PF00652.22 KLO10857.1 - 0.012 15.9 0.1 0.016 15.4 0.1 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain GATA PF00320.27 KLO10858.1 - 1.6e-08 34.0 7.6 2.2e-08 33.6 7.6 1.2 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 KLO10858.1 - 0.016 15.3 0.9 0.018 15.1 0.9 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf YL1 PF05764.13 KLO10859.1 - 0.13 12.4 3.2 0.16 12.0 3.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.12 KLO10859.1 - 0.13 11.5 5.3 0.2 11.0 5.3 1.3 1 0 0 1 1 1 0 NOA36 protein Spt5_N PF11942.8 KLO10859.1 - 0.33 12.0 10.2 0.71 10.9 10.2 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Cwf_Cwc_15 PF04889.12 KLO10859.1 - 0.35 10.5 7.2 0.54 9.9 7.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 KLO10859.1 - 0.41 11.1 10.8 0.9 10.0 10.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 KLO10859.1 - 0.99 9.8 9.1 1.8 9.0 8.5 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GCIP PF13324.6 KLO10859.1 - 2.8 7.5 6.8 45 3.5 5.1 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.9 KLO10859.1 - 5.9 5.9 11.2 8.3 5.4 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) COesterase PF00135.28 KLO10861.1 - 1.3e-50 172.8 0.0 1.5e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO10861.1 - 2.8e-08 33.9 0.7 1.2e-07 31.8 0.2 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold F-box-like PF12937.7 KLO10862.1 - 8e-06 25.7 0.3 8e-06 25.7 0.3 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO10862.1 - 0.0014 18.4 1.0 0.0014 18.4 1.0 2.4 2 0 0 2 2 2 1 F-box domain Sec1 PF00995.23 KLO10864.1 - 5.2e-109 366.1 0.0 6.7e-109 365.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Peptidase_S10 PF00450.22 KLO10865.1 - 2.5e-65 221.6 2.6 3.3e-64 217.8 2.6 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KLO10865.1 - 0.0037 16.6 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 ERAP1_C PF11838.8 KLO10866.1 - 2.7e-67 227.6 1.7 4.6e-67 226.8 1.7 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KLO10866.1 - 2.1e-65 220.4 0.1 3.9e-65 219.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KLO10866.1 - 8.2e-45 153.3 0.0 1.3e-44 152.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain CVNH PF08881.10 KLO10867.1 - 2.4e-11 44.2 1.8 1.1e-10 42.1 1.7 2.0 1 1 0 1 1 1 1 CVNH domain MCM_OB PF17207.3 KLO10868.1 - 0.00021 21.2 0.1 0.00075 19.3 0.1 1.9 1 1 0 1 1 1 1 MCM OB domain MCM PF00493.23 KLO10868.1 - 0.0074 15.4 0.0 0.0099 15.0 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain DUF4217 PF13959.6 KLO10869.1 - 5.3e-07 29.8 0.4 1.9e-06 28.0 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) DEAD PF00270.29 KLO10869.1 - 6.8e-05 22.7 0.3 0.25 11.1 0.0 3.0 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO10869.1 - 0.0001 22.6 0.0 0.00038 20.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PBP1_TM PF14812.6 KLO10869.1 - 0.6 10.5 4.7 1.1 9.6 4.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RSN1_7TM PF02714.15 KLO10870.1 - 1.3e-76 257.5 20.2 2.1e-76 256.9 20.2 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KLO10870.1 - 2.4e-37 128.1 0.5 2.4e-37 128.1 0.5 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KLO10870.1 - 1.6e-36 126.2 0.0 2.3e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter BCS1_N PF08740.11 KLO10871.1 - 2.3e-42 145.1 1.2 4.4e-42 144.2 1.2 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KLO10871.1 - 9.4e-13 48.7 0.0 6.4e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KLO10871.1 - 0.00043 20.7 0.1 0.0014 19.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KLO10871.1 - 0.018 15.2 0.2 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KLO10871.1 - 0.023 13.8 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KLO10871.1 - 0.055 14.0 0.0 0.29 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KLO10871.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KLO10871.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KLO10871.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Lactamase_B PF00753.27 KLO10872.1 - 3.4e-08 33.7 0.0 7.1e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily CYYR1 PF10873.8 KLO10875.1 - 0.032 14.7 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Lactamase_B PF00753.27 KLO10876.1 - 1.5e-07 31.6 1.3 5.9e-07 29.7 1.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily OPT PF03169.15 KLO10879.1 - 4.4e-181 603.7 47.2 5e-181 603.5 47.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein LRR_8 PF13855.6 KLO10880.1 - 2.8e-07 30.2 19.5 0.001 18.8 2.1 3.7 2 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KLO10880.1 - 0.0029 18.0 16.7 0.08 13.4 0.2 4.8 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 KLO10880.1 - 0.033 14.5 1.8 0.051 13.9 0.3 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Peptidase_C2 PF00648.21 KLO10881.1 - 2.2e-23 82.7 0.0 3.7e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KLO10881.1 - 2.1e-13 50.7 0.1 0.00094 19.5 0.0 5.0 4 1 0 4 4 4 3 Calpain large subunit, domain III MIT PF04212.18 KLO10881.1 - 2.4e-05 24.3 5.3 4.6e-05 23.4 5.3 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Rit1_C PF17184.4 KLO10882.1 - 3.7e-90 302.1 0.2 1.3e-55 188.8 0.0 2.1 2 0 0 2 2 2 2 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KLO10882.1 - 1.4e-21 76.8 0.0 5.3e-21 75.0 0.0 1.9 2 0 0 2 2 2 1 Rit1 DUSP-like domain 3HCDH_N PF02737.18 KLO10883.1 - 4.8e-48 163.4 1.8 2.6e-47 161.0 1.8 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KLO10883.1 - 1.7e-31 108.7 0.1 7.4e-31 106.6 0.0 2.1 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KLO10883.1 - 0.013 15.7 0.7 0.045 13.9 0.7 1.9 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KLO10883.1 - 0.11 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ly49 PF08391.10 KLO10885.1 - 0.18 12.2 2.0 0.37 11.2 2.0 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF3332 PF11810.8 KLO10885.1 - 1.1 8.9 6.9 1.2 8.8 6.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3332) DDE_Tnp_4 PF13359.6 KLO10886.1 - 6.9e-17 61.6 0.0 8.1e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KLO10886.1 - 0.0086 15.7 0.0 0.0099 15.5 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein TB2_DP1_HVA22 PF03134.19 KLO10886.1 - 0.098 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Nipped-B_C PF12830.7 KLO10892.1 - 0.065 13.2 0.3 0.1 12.5 0.3 1.3 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Hva1_TUDOR PF11160.8 KLO10893.1 - 3.2e-05 24.0 0.0 0.00015 21.9 0.0 1.9 1 1 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Mito_carr PF00153.27 KLO10894.1 - 7.1e-51 170.1 0.7 4.6e-16 58.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ISPD_C PF18706.1 KLO10894.1 - 0.063 12.9 0.1 11 5.6 0.0 2.3 2 0 0 2 2 2 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Menin PF05053.13 KLO10901.1 - 0.8 8.0 5.4 0.86 7.9 5.4 1.0 1 0 0 1 1 1 0 Menin SelP_N PF04592.14 KLO10901.1 - 2.1 7.7 10.3 2.7 7.3 10.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MAP65_ASE1 PF03999.12 KLO10901.1 - 3.9 6.1 9.4 4.4 5.9 9.4 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Macoilin PF09726.9 KLO10901.1 - 8.9 4.7 11.3 10 4.5 11.3 1.0 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 KLO10901.1 - 8.9 5.0 8.1 9.9 4.9 8.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cyclin_N PF00134.23 KLO10902.1 - 6.6e-12 45.3 0.0 8.1e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KLO10902.1 - 3.9e-06 27.3 0.0 5.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin Colipase PF01114.18 KLO10904.1 - 0.82 9.4 6.7 0.52 10.0 0.8 2.3 2 0 0 2 2 2 0 Colipase, N-terminal domain CENP-F_leu_zip PF10473.9 KLO10905.1 - 0.00016 21.7 8.8 0.0019 18.2 8.3 2.8 2 1 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lectin_N PF03954.14 KLO10905.1 - 0.00033 20.4 1.1 0.3 10.8 0.2 2.8 1 1 1 2 2 2 2 Hepatic lectin, N-terminal domain TPR_MLP1_2 PF07926.12 KLO10905.1 - 0.00077 19.5 0.0 0.00077 19.5 0.0 3.2 2 1 1 3 3 2 1 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 KLO10905.1 - 0.0012 18.9 3.8 0.23 11.6 0.1 3.5 1 1 3 4 4 4 2 bZIP transcription factor DUF5082 PF16888.5 KLO10905.1 - 0.0044 17.3 2.6 0.0089 16.3 1.3 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) APG6_N PF17675.1 KLO10905.1 - 0.014 15.9 2.6 0.014 15.9 2.6 2.2 2 0 0 2 2 1 0 Apg6 coiled-coil region DUF883 PF05957.13 KLO10905.1 - 0.036 14.7 0.8 0.12 13.0 0.3 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF730 PF05325.11 KLO10905.1 - 0.037 14.0 1.0 0.22 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF730) DUF2935 PF11155.8 KLO10905.1 - 0.05 13.9 0.7 7.6 6.9 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Exonuc_VII_L PF02601.15 KLO10905.1 - 0.06 12.9 5.3 0.025 14.2 2.7 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Phlebovirus_NSM PF07246.11 KLO10905.1 - 0.06 12.7 3.9 0.12 11.7 3.9 1.5 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4407 PF14362.6 KLO10905.1 - 0.14 11.5 3.3 0.54 9.6 3.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.15 KLO10905.1 - 0.19 11.8 0.6 4.6 7.4 0.0 3.2 2 1 0 3 3 3 0 Basic region leucine zipper Plasmid_RAQPRD PF09686.10 KLO10905.1 - 0.27 11.5 0.8 1.1 9.6 0.1 2.3 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF1664 PF07889.12 KLO10905.1 - 0.32 11.1 9.4 5.9 7.0 2.1 3.0 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KLO10905.1 - 0.49 9.2 12.7 0.031 13.2 7.0 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KLO10905.1 - 0.56 10.2 18.2 0.079 13.0 6.8 3.4 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding SHE3 PF17078.5 KLO10905.1 - 0.75 9.5 11.0 0.16 11.7 2.8 2.9 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 CEP63 PF17045.5 KLO10905.1 - 1 9.2 9.7 0.37 10.7 4.5 2.3 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa FAM184 PF15665.5 KLO10905.1 - 1.1 9.0 7.5 0.42 10.4 4.2 2.1 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B DivIC PF04977.15 KLO10905.1 - 1.1 9.1 3.7 34 4.3 0.0 3.5 1 1 2 3 3 3 0 Septum formation initiator Fez1 PF06818.15 KLO10905.1 - 1.3 9.4 8.6 0.4 11.1 3.2 2.3 1 1 1 2 2 2 0 Fez1 DUF4618 PF15397.6 KLO10905.1 - 1.7 8.0 10.8 0.23 10.9 4.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) ADIP PF11559.8 KLO10905.1 - 2.9 8.0 13.9 0.52 10.4 0.2 3.4 3 1 1 4 4 3 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 KLO10905.1 - 3.8 8.0 11.1 2.2 8.8 0.4 3.7 2 1 1 3 3 2 0 Cell division protein ZapB ATG16 PF08614.11 KLO10905.1 - 3.9 7.7 17.5 0.023 14.9 5.9 2.9 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 KLO10905.1 - 4.4 7.3 20.6 0.8 9.7 2.5 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus JIP_LZII PF16471.5 KLO10905.1 - 5.5 7.2 9.4 4.2 7.6 2.6 3.9 3 1 1 4 4 3 0 JNK-interacting protein leucine zipper II AAA_13 PF13166.6 KLO10905.1 - 5.6 5.5 10.7 0.19 10.4 4.4 1.6 2 0 0 2 2 2 0 AAA domain Transposase_21 PF02992.14 KLO10906.1 - 8.8e-07 28.4 0.1 2.5e-05 23.6 0.0 2.5 3 0 0 3 3 3 1 Transposase family tnp2 DUF4218 PF13960.6 KLO10906.1 - 0.091 12.4 0.0 0.27 10.9 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4218) PADR1 PF08063.12 KLO10906.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 PADR1 (NUC008) domain Cyclin_N PF00134.23 KLO10907.1 - 2.6e-11 43.3 0.0 3.2e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KLO10907.1 - 6.9e-06 26.5 0.0 9.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin AAA PF00004.29 KLO10908.1 - 2.1e-92 306.4 0.0 3.6e-46 156.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KLO10908.1 - 2.2e-19 69.0 1.1 2.2e-11 43.4 0.3 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KLO10908.1 - 5.7e-13 48.9 0.0 3.7e-05 23.5 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KLO10908.1 - 1.8e-11 44.4 0.0 1.5e-05 25.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KLO10908.1 - 1.2e-09 38.5 0.0 0.0011 19.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KLO10908.1 - 1.7e-09 37.8 0.2 0.002 18.1 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KLO10908.1 - 8.2e-08 32.8 0.0 0.0008 19.8 0.0 4.1 2 2 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KLO10908.1 - 1.7e-07 30.8 0.1 0.0062 15.8 0.0 2.5 2 1 0 2 2 2 2 TIP49 P-loop domain CDC48_N PF02359.18 KLO10908.1 - 2.2e-07 30.9 0.1 8.2e-07 29.1 0.1 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.6 KLO10908.1 - 1e-06 29.1 0.1 0.038 14.3 0.0 4.0 2 2 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KLO10908.1 - 9.2e-06 25.2 0.4 0.026 13.9 0.0 2.8 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KLO10908.1 - 1.9e-05 24.5 0.0 0.021 14.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 KLO10908.1 - 2.4e-05 24.0 0.1 0.32 10.6 0.0 3.2 2 1 1 3 3 3 2 AAA domain ATPase PF06745.13 KLO10908.1 - 3.3e-05 23.3 0.4 0.18 11.2 0.0 3.4 2 1 0 3 3 3 1 KaiC AAA_7 PF12775.7 KLO10908.1 - 0.00019 21.0 0.0 0.018 14.6 0.0 2.6 2 1 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KLO10908.1 - 0.00031 21.1 0.0 0.018 15.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 KLO10908.1 - 0.00038 21.0 0.0 0.02 15.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain CDC48_2 PF02933.17 KLO10908.1 - 0.0004 20.1 0.0 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.6 KLO10908.1 - 0.00052 20.1 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 KLO10908.1 - 0.00061 19.0 0.1 0.0091 15.1 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 KLO10908.1 - 0.00075 19.4 0.0 0.84 9.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KLO10908.1 - 0.00075 20.0 0.0 0.14 12.7 0.0 2.9 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 KLO10908.1 - 0.0011 18.7 0.0 0.34 10.6 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 KLO10908.1 - 0.0023 18.2 0.0 0.12 12.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain Vps4_C PF09336.10 KLO10908.1 - 0.0024 17.8 0.0 0.12 12.4 0.0 3.3 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain PhoH PF02562.16 KLO10908.1 - 0.0047 16.4 0.1 0.43 10.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Bac_DnaA PF00308.18 KLO10908.1 - 0.0048 16.8 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein DUF815 PF05673.13 KLO10908.1 - 0.0084 15.3 0.0 0.041 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 KLO10908.1 - 0.0085 15.9 0.0 0.62 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KLO10908.1 - 0.011 15.5 0.0 0.44 10.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain ResIII PF04851.15 KLO10908.1 - 0.017 15.2 0.0 5.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 KLO10908.1 - 0.018 15.2 0.0 8.3 6.5 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KLO10908.1 - 0.02 14.8 0.0 4.1 7.3 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KLO10908.1 - 0.024 14.6 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 KLO10908.1 - 0.027 13.7 0.0 0.43 9.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KLO10908.1 - 0.064 13.0 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 KLO10908.1 - 0.065 13.7 0.0 3.1 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KLO10908.1 - 0.11 12.5 0.2 3.7 7.4 0.0 2.9 3 0 0 3 3 2 0 NTPase AAA_30 PF13604.6 KLO10908.1 - 0.11 12.2 0.2 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KLO10908.1 - 0.12 12.2 0.0 0.99 9.3 0.0 2.5 2 1 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KLO10908.1 - 0.14 12.5 0.3 3.3 8.0 0.0 3.1 3 1 0 4 4 4 0 AAA domain NB-ARC PF00931.22 KLO10908.1 - 0.15 11.2 0.0 0.58 9.3 0.0 2.0 3 0 0 3 3 2 0 NB-ARC domain Arrestin_N PF00339.29 KLO10909.1 - 0.0061 16.6 0.4 0.38 10.8 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain FAD-oxidase_C PF02913.19 KLO10910.1 - 6.1e-56 189.8 0.0 9.1e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KLO10910.1 - 2.2e-32 111.7 0.0 3.8e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain eIF3_N PF09440.10 KLO10911.1 - 5.6e-44 149.8 6.7 1.7e-43 148.3 4.5 2.6 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KLO10911.1 - 1.1e-07 32.3 2.3 1.5e-07 31.8 0.2 2.2 2 0 0 2 2 2 1 PCI domain DAHP_synth_2 PF01474.16 KLO10912.1 - 2.5e-196 652.4 0.0 2.8e-196 652.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family HECT PF00632.25 KLO10915.1 - 1.1e-94 317.4 0.0 1.6e-94 316.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KLO10915.1 - 0.0033 17.1 0.4 0.0033 17.1 0.4 2.0 2 0 0 2 2 2 1 IQ calmodulin-binding motif Pkinase_Tyr PF07714.17 KLO10916.1 - 2e-25 89.6 0.0 2.8e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO10916.1 - 4.6e-24 85.2 0.0 6e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO10916.1 - 3.1e-05 23.4 0.0 3.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO10916.1 - 0.00016 21.7 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO10916.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KLO10916.1 - 0.0029 17.0 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KLO10916.1 - 0.099 11.7 0.1 0.23 10.5 0.1 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Sortilin-Vps10 PF15902.5 KLO10917.1 - 5.9e-13 48.4 2.7 0.00045 19.1 0.0 4.7 5 0 0 5 5 5 3 Sortilin, neurotensin receptor 3, BNR PF02012.20 KLO10917.1 - 9.1e-09 34.0 33.0 0.31 11.2 0.0 9.2 10 0 0 10 10 10 6 BNR/Asp-box repeat BNR_2 PF13088.6 KLO10917.1 - 0.00036 19.9 6.6 14 4.9 0.0 5.8 4 1 0 5 5 5 2 BNR repeat-like domain BNR_6 PF15899.5 KLO10917.1 - 0.72 10.1 10.4 2e+02 2.5 0.1 6.9 8 0 0 8 8 8 0 BNR-Asp box repeat Methyltransf_25 PF13649.6 KLO10918.1 - 1.3e-17 64.3 0.0 7.2e-17 61.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO10918.1 - 1.6e-13 51.1 0.1 6e-13 49.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO10918.1 - 3.3e-12 46.6 0.0 7.1e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO10918.1 - 9.3e-09 35.2 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO10918.1 - 1e-07 31.5 0.0 1.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KLO10918.1 - 5e-07 30.4 0.0 1.3e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KLO10918.1 - 0.00029 21.0 0.0 0.00061 20.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KLO10918.1 - 0.0026 17.4 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KLO10918.1 - 0.0033 17.0 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 KLO10918.1 - 0.0036 16.6 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 KLO10918.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KLO10918.1 - 0.067 12.6 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase SRF-TF PF00319.18 KLO10919.1 - 6.4e-21 73.6 0.1 8.8e-21 73.1 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) F-box-like PF12937.7 KLO10921.1 - 1.5e-06 28.0 0.4 4.1e-06 26.6 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO10921.1 - 0.026 14.4 0.2 0.069 13.0 0.2 1.8 1 0 0 1 1 1 0 F-box domain Abhydrolase_4 PF08386.10 KLO10922.1 - 1.5e-24 86.0 0.0 2.8e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KLO10922.1 - 1.6e-24 86.9 0.0 1.2e-21 77.5 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO10922.1 - 0.029 13.6 0.1 5.2 6.3 0.0 3.3 3 1 0 3 3 3 0 Serine aminopeptidase, S33 PIF1 PF05970.14 KLO10923.1 - 4.9e-59 200.3 0.8 3.2e-56 191.1 0.8 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KLO10923.1 - 9.1e-22 77.7 0.0 1.4e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO10923.1 - 2.1e-12 47.6 0.0 5.3e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 KLO10923.1 - 1.6e-08 33.0 0.4 1.2e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 KLO10923.1 - 4.1e-07 30.0 0.6 0.0067 16.2 0.2 3.9 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KLO10923.1 - 6.3e-07 29.7 0.0 1.7e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KLO10923.1 - 5.4e-05 22.9 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KLO10923.1 - 0.00048 20.5 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KLO10923.1 - 0.0023 17.5 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 KLO10923.1 - 0.0028 17.7 0.1 0.04 13.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KLO10923.1 - 0.0045 16.7 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF2075 PF09848.9 KLO10923.1 - 0.0082 15.4 0.0 0.35 10.1 0.1 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KLO10923.1 - 0.012 15.6 0.0 2.6 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 KLO10923.1 - 0.013 15.0 0.0 0.048 13.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 KLO10923.1 - 0.014 15.9 0.1 0.27 11.8 0.1 2.7 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 KLO10923.1 - 0.015 15.2 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA PF00004.29 KLO10923.1 - 0.017 15.5 0.1 0.046 14.1 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 KLO10923.1 - 0.027 14.2 0.0 3.2 7.5 0.0 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.12 KLO10923.1 - 0.027 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 KLO10923.1 - 0.04 13.7 0.2 1 9.1 0.0 2.4 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 KLO10923.1 - 0.048 13.6 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_32 PF13654.6 KLO10923.1 - 0.057 12.2 0.0 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KLO10923.1 - 0.12 11.6 0.0 0.46 9.6 0.0 1.9 1 1 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 KLO10923.1 - 0.12 12.5 0.3 1 9.5 0.1 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KLO10923.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF5089 PF17002.5 KLO10924.1 - 0.014 15.2 2.0 0.014 15.2 0.6 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF5089) Ebp2 PF05890.12 KLO10924.1 - 0.056 13.0 1.6 1.3 8.6 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic rRNA processing protein EBP2 F-box-like PF12937.7 KLO10925.1 - 0.078 12.9 0.0 0.76 9.7 0.0 2.4 2 0 0 2 2 2 0 F-box-like CxC2 PF18803.1 KLO10927.1 - 2e-14 53.7 0.2 3.4e-14 52.9 0.0 1.4 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases Retrotrans_gag PF03732.17 KLO10931.1 - 3.1e-06 27.4 0.8 7.4e-06 26.2 0.8 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein PIF1 PF05970.14 KLO10934.1 - 1.6e-12 47.3 0.0 2.2e-12 46.9 0.0 1.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KLO10934.1 - 4.5e-08 33.0 0.0 7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO10934.1 - 5.2e-06 26.9 0.0 1.1e-05 25.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO10934.1 - 0.0012 19.3 0.0 0.0028 18.1 0.0 1.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KLO10934.1 - 0.0089 16.0 0.0 0.019 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KLO10934.1 - 0.022 15.0 0.3 0.055 13.7 0.3 1.8 1 1 0 1 1 1 0 AAA domain DUF799 PF05643.11 KLO10934.1 - 0.025 14.2 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial lipoprotein (DUF799) IstB_IS21 PF01695.17 KLO10934.1 - 0.034 13.9 0.1 0.16 11.7 0.1 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KLO10934.1 - 0.035 13.5 0.3 0.062 12.7 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 KLO10934.1 - 0.035 14.5 0.1 0.078 13.4 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 KLO10934.1 - 0.058 13.2 0.2 0.73 9.6 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein AFG1_ATPase PF03969.16 KLO10934.1 - 0.059 12.2 0.0 0.072 12.0 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase AAA_18 PF13238.6 KLO10934.1 - 0.1 13.1 0.2 0.47 11.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KLO10934.1 - 0.14 11.8 0.1 0.44 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KLO10934.1 - 0.15 11.8 0.1 0.33 10.7 0.0 1.6 1 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KLO10934.1 - 0.19 10.9 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin CobA_CobO_BtuR PF02572.15 KLO10935.1 - 0.047 14.0 0.0 0.05 13.9 0.0 1.3 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF3880 PF12996.7 KLO10935.1 - 0.078 13.1 0.2 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 DUF based on E. rectale Gene description (DUF3880) Helitron_like_N PF14214.6 KLO10936.1 - 8e-20 71.9 0.0 9.7e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus HNH PF01844.23 KLO10937.1 - 0.051 13.8 0.1 0.094 12.9 0.1 1.5 1 0 0 1 1 1 0 HNH endonuclease F-box PF00646.33 KLO10938.1 - 4.1e-05 23.3 1.0 8.5e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KLO10938.1 - 0.00012 21.9 0.0 0.00034 20.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KLO10939.1 - 6.1e-24 84.6 41.6 6.6e-16 58.2 4.4 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO10939.1 - 1.3e-17 63.8 0.1 1.3e-17 63.8 0.1 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter Cadherin_C_2 PF16492.5 KLO10939.1 - 0.19 12.5 0.0 0.19 12.5 0.0 2.1 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal FB_lectin PF07367.11 KLO10940.1 - 1.8e-58 196.5 0.6 2e-58 196.3 0.6 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin ABC2_membrane PF01061.24 KLO10942.1 - 1.8e-32 112.5 17.3 1.8e-32 112.5 17.3 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KLO10942.1 - 1.1e-21 77.8 0.1 1.7e-21 77.2 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KLO10942.1 - 1.1e-08 35.3 0.0 0.0054 16.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KLO10942.1 - 0.0031 16.7 21.4 0.0077 15.4 21.4 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA PF00004.29 KLO10942.1 - 0.012 16.1 0.1 0.14 12.6 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KLO10942.1 - 0.038 13.7 0.1 0.094 12.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KLO10942.1 - 0.049 13.5 0.2 0.55 10.1 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 KLO10942.1 - 0.066 13.1 0.1 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_16 PF13191.6 KLO10942.1 - 0.09 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 KLO10942.1 - 0.094 13.0 0.0 0.28 11.5 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KLO10942.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KLO10942.1 - 0.23 10.8 0.2 0.82 9.1 0.2 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Asp PF00026.23 KLO10943.1 - 6.8e-11 42.1 0.1 2.8e-05 23.7 0.0 2.3 2 1 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KLO10943.1 - 0.0002 22.0 1.0 0.0022 18.6 0.5 2.9 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 KLO10943.1 - 0.0031 18.1 0.1 0.11 13.1 0.0 2.9 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease TMEM154 PF15102.6 KLO10943.1 - 0.038 13.9 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 KLO10943.1 - 0.092 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) CCSMST1 PF15013.6 KLO10943.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 CCSMST1 family BTB PF00651.31 KLO10944.1 - 4.3e-09 36.6 0.0 4.7e-08 33.2 0.0 2.3 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO10948.1 - 0.00014 22.0 0.0 0.0004 20.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO10949.1 - 8.1e-09 35.7 0.0 2.7e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.26 KLO10950.1 - 0.017 15.5 13.2 0.18 12.3 0.4 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type WD40 PF00400.32 KLO10951.1 - 1.6e-40 136.3 24.8 1.6e-07 31.9 0.1 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO10951.1 - 1.9e-13 50.5 0.1 0.11 12.8 0.0 6.9 2 2 6 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KLO10951.1 - 6.4e-09 35.6 0.0 5.9e-05 22.5 0.0 2.9 3 0 0 3 3 3 2 WD40-like domain F-box-like PF12937.7 KLO10951.1 - 2.4e-06 27.3 0.2 2.4e-06 27.3 0.2 2.3 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.8 KLO10951.1 - 2.2e-05 23.4 1.3 1.1 7.8 0.0 4.6 2 1 3 5 5 5 2 Nucleoporin Nup120/160 F-box PF00646.33 KLO10951.1 - 0.0078 16.1 0.4 0.021 14.7 0.4 1.8 1 0 0 1 1 1 1 F-box domain DUF5046 PF16465.5 KLO10951.1 - 0.03 13.8 0.0 22 4.4 0.0 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF5046) RMP PF14996.6 KLO10952.1 - 0.0039 17.4 0.0 0.0051 17.0 0.0 1.2 1 0 0 1 1 1 1 Retinal Maintenance Arcadin_1 PF18653.1 KLO10952.1 - 0.028 14.5 0.0 0.048 13.7 0.0 1.5 1 1 0 1 1 1 0 Arcadin 1 PEMT PF04191.13 KLO10953.1 - 6.2e-07 29.8 1.4 9e-07 29.3 0.1 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KLO10953.1 - 4.1e-06 27.1 0.0 7.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KLO10953.1 - 0.042 12.6 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family zf-MYND PF01753.18 KLO10954.1 - 3.4e-10 39.8 12.5 6.4e-10 39.0 12.5 1.5 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 KLO10954.1 - 0.29 11.5 5.8 0.63 10.5 5.8 1.5 1 0 0 1 1 1 0 Rhodanase C-terminal BTB PF00651.31 KLO10955.1 - 2.6e-09 37.3 0.0 5.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO10956.1 - 4.4e-07 30.1 0.0 9.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Curto_V2 PF07325.11 KLO10957.1 - 0.059 13.2 1.1 0.11 12.4 0.3 1.7 2 0 0 2 2 2 0 Curtovirus V2 protein Thioredoxin_3 PF13192.6 KLO10957.1 - 0.11 12.5 1.4 0.74 9.9 0.1 2.5 2 2 0 2 2 2 0 Thioredoxin domain WD40 PF00400.32 KLO10958.1 - 8.1e-97 314.5 48.5 3e-08 34.2 0.1 14.8 14 0 0 14 14 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO10958.1 - 2.6e-38 130.2 5.5 1.8e-05 25.0 0.0 11.2 1 1 10 12 12 12 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO10958.1 - 3.5e-15 55.8 6.8 0.018 14.1 0.1 8.5 3 3 4 9 9 9 5 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KLO10958.1 - 6.1e-13 49.1 0.0 0.016 15.1 0.1 4.6 2 1 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KLO10958.1 - 2.6e-07 30.3 0.1 0.0076 15.6 0.1 5.1 4 1 1 5 5 5 1 WD40-like domain Frtz PF11768.8 KLO10958.1 - 5.8e-07 28.2 0.0 0.53 8.5 0.0 5.1 3 1 3 6 6 6 2 WD repeat-containing and planar cell polarity effector protein Fritz NACHT PF05729.12 KLO10958.1 - 1.6e-06 28.2 0.3 2e-05 24.6 0.3 2.3 1 1 0 1 1 1 1 NACHT domain PALB2_WD40 PF16756.5 KLO10958.1 - 0.00047 19.2 0.4 0.024 13.6 0.2 2.7 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain AAA PF00004.29 KLO10958.1 - 0.00087 19.7 0.0 0.0028 18.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Nbas_N PF15492.6 KLO10958.1 - 0.0016 17.9 0.5 0.092 12.1 0.0 3.9 3 1 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal AAA_16 PF13191.6 KLO10958.1 - 0.0082 16.5 0.0 0.029 14.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain ELYS-bb PF16687.5 KLO10958.1 - 0.023 13.3 1.9 34 2.9 0.0 4.5 3 2 2 5 5 5 0 beta-propeller of ELYS nucleoporin ATPase_2 PF01637.18 KLO10958.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Cu-oxidase PF00394.22 KLO10959.1 - 1.7e-51 174.5 0.1 2.5e-45 154.4 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KLO10959.1 - 2.3e-34 118.1 5.4 1.6e-33 115.4 0.0 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KLO10959.1 - 2.6e-33 114.5 3.0 4.5e-31 107.3 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase DUF3685 PF12452.8 KLO10960.1 - 0.21 11.3 0.0 0.44 10.2 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3685) Cu-oxidase PF00394.22 KLO10961.1 - 1.7e-53 181.0 1.4 1.7e-47 161.5 0.2 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KLO10961.1 - 2.6e-35 121.1 7.5 1.9e-33 115.1 0.0 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KLO10961.1 - 8.6e-32 109.6 4.1 6.6e-31 106.8 0.5 3.1 3 1 1 4 4 4 1 Multicopper oxidase DDE_Tnp_IS1 PF03400.13 KLO10964.1 - 0.12 12.7 0.2 0.26 11.7 0.1 1.6 2 0 0 2 2 2 0 IS1 transposase GMC_oxred_N PF00732.19 KLO10967.1 - 1e-70 238.5 0.0 1.3e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO10967.1 - 1.1e-35 123.2 0.0 1.9e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KLO10967.1 - 6.7e-06 25.4 0.2 9.9e-06 24.8 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KLO10967.1 - 1.6e-05 24.7 1.6 0.00069 19.3 0.3 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO10967.1 - 9e-05 21.7 0.4 0.0038 16.4 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KLO10967.1 - 0.00048 20.3 0.1 0.0013 19.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO10967.1 - 0.0028 16.9 0.0 0.0091 15.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO10967.1 - 0.0039 16.4 0.1 0.0093 15.2 0.1 1.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KLO10967.1 - 0.0095 15.9 0.3 5 7.1 0.1 2.3 1 1 1 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KLO10967.1 - 0.036 12.8 0.0 0.065 11.9 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KLO10967.1 - 0.055 14.0 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KLO10967.1 - 0.075 11.9 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KLO10967.1 - 0.099 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DPPIV_N PF00930.21 KLO10968.1 - 1.7e-86 290.2 0.0 2.3e-86 289.8 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KLO10968.1 - 7.1e-43 146.5 0.7 1.2e-42 145.8 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KLO10968.1 - 8.4e-05 22.3 0.4 0.00023 20.8 0.4 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KLO10968.1 - 0.0015 19.2 3.6 0.0081 16.8 0.3 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO10968.1 - 0.03 14.0 0.1 0.058 13.0 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 KLO10968.1 - 0.15 10.7 0.0 0.26 9.9 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Mito_carr PF00153.27 KLO10969.1 - 2.9e-61 203.4 0.6 3.4e-21 75.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 KLO10970.1 - 2.2e-08 33.8 1.2 4.3e-08 32.9 0.2 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO10970.1 - 0.0044 17.4 3.0 9.1 6.9 0.0 4.4 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) SYS1 PF09801.9 KLO10971.1 - 3.8e-28 98.5 1.0 3.5e-20 72.6 1.2 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network BCS1_N PF08740.11 KLO10975.1 - 2.6e-46 158.0 4.1 2.6e-46 158.0 4.1 2.7 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 KLO10975.1 - 1e-14 55.1 0.0 3.6e-13 50.1 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KLO10975.1 - 0.00068 19.8 0.4 0.0031 17.7 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO10975.1 - 0.0011 19.3 0.0 0.0011 19.3 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain MAP7 PF05672.11 KLO10975.1 - 0.0026 17.5 39.4 0.0026 17.5 39.4 2.0 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family Viral_helicase1 PF01443.18 KLO10975.1 - 0.011 15.4 0.0 0.011 15.4 0.0 1.8 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KLO10975.1 - 0.013 15.3 16.6 2.9 7.6 14.7 2.5 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KLO10975.1 - 0.021 14.2 0.3 0.41 10.0 0.0 2.3 2 0 0 2 2 2 0 KaiC RuvB_N PF05496.12 KLO10975.1 - 0.043 13.6 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KLO10975.1 - 0.065 13.1 0.3 0.31 11.0 0.1 2.3 3 0 0 3 3 3 0 NACHT domain XRN_M PF17846.1 KLO10975.1 - 0.089 11.7 10.0 0.15 10.9 10.0 1.4 1 0 0 1 1 1 0 Xrn1 helical domain DUF3439 PF11921.8 KLO10975.1 - 0.097 12.6 5.1 0.31 11.0 5.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MPM1 PF17234.2 KLO10975.1 - 0.3 11.4 0.0 0.3 11.4 0.0 3.7 3 1 0 3 3 1 0 Mitochondrial peculiar membrane protein 1 AAA_23 PF13476.6 KLO10975.1 - 0.32 11.5 23.6 12 6.3 22.6 2.7 2 0 0 2 2 2 0 AAA domain Plasmodium_Vir PF05795.11 KLO10975.1 - 0.35 10.3 17.4 0.77 9.1 17.4 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DDRGK PF09756.9 KLO10975.1 - 0.78 9.3 38.3 1.9e+02 1.6 42.6 2.4 2 0 0 2 2 2 0 DDRGK domain SLC12 PF03522.15 KLO10975.1 - 0.91 8.5 12.5 1.4 7.9 12.5 1.4 1 0 0 1 1 1 0 Solute carrier family 12 DUF2151 PF10221.9 KLO10975.1 - 1.8 7.0 17.8 2.9 6.4 17.8 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator ALMT PF11744.8 KLO10975.1 - 6.3 5.5 12.5 9.4 4.9 12.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter TERB2 PF15101.6 KLO10975.1 - 6.4 6.8 11.1 15 5.5 11.1 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 KLO10975.1 - 6.8 5.6 8.0 11 4.9 8.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein Dynamin_M PF01031.20 KLO10976.1 - 3.8e-110 367.6 0.2 1.2e-109 366.0 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KLO10976.1 - 2.8e-57 193.4 0.0 5.4e-57 192.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KLO10976.1 - 1e-29 102.5 1.0 1e-29 102.5 1.0 2.4 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KLO10976.1 - 2.1e-05 24.6 0.1 0.00011 22.2 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Condensin2nSMC PF12422.8 KLO10976.1 - 0.0043 17.2 0.3 0.038 14.2 0.1 2.3 2 0 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit FeoB_N PF02421.18 KLO10976.1 - 0.16 11.5 0.2 9.6 5.7 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B F-box-like PF12937.7 KLO10977.1 - 4.1e-05 23.4 1.9 6.3e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO10977.1 - 0.0033 17.8 12.0 8.5 7.0 0.1 5.9 4 2 1 6 6 6 3 Leucine Rich repeats (2 copies) SE PF08491.10 KLO10978.1 - 9.9e-90 300.3 0.0 1.3e-89 299.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KLO10978.1 - 1.8e-08 34.4 0.1 0.0008 19.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KLO10978.1 - 3.9e-07 29.7 0.5 0.0029 16.9 0.4 2.8 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 KLO10978.1 - 0.00049 19.3 4.4 0.42 9.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KLO10978.1 - 0.00078 18.8 0.2 0.0012 18.1 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KLO10978.1 - 0.0025 16.9 0.1 0.013 14.5 0.0 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein GIDA PF01134.22 KLO10978.1 - 0.0032 16.6 0.8 0.85 8.6 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KLO10978.1 - 0.0066 16.7 0.1 0.016 15.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KLO10978.1 - 0.0096 14.8 0.3 2 7.2 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase GMC_oxred_N PF00732.19 KLO10978.1 - 0.011 15.1 0.3 0.78 9.1 0.1 2.3 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.6 KLO10978.1 - 0.16 11.9 0.1 0.54 10.2 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding RPN5_C PF18098.1 KLO10979.1 - 0.065 13.4 0.2 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain CoA_binding_2 PF13380.6 KLO10979.1 - 0.097 13.2 0.1 0.52 10.8 0.1 1.8 1 1 1 2 2 2 0 CoA binding domain Cu-oxidase PF00394.22 KLO10980.1 - 2e-50 171.0 0.0 3e-47 160.7 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KLO10980.1 - 8.9e-38 129.0 0.3 3.4e-35 120.6 0.0 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KLO10980.1 - 3.2e-37 127.3 2.2 1.1e-35 122.3 0.0 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KLO10981.1 - 8.6e-52 175.5 0.1 7.6e-48 162.6 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KLO10981.1 - 1.2e-38 131.8 0.2 7e-35 119.6 0.0 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KLO10981.1 - 5.4e-38 129.8 5.1 2.6e-36 124.4 0.0 3.7 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KLO10982.1 - 4e-52 176.6 3.3 1.6e-47 161.6 0.2 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KLO10982.1 - 1.2e-38 132.0 2.3 6.6e-36 123.1 0.0 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KLO10982.1 - 8.9e-38 129.0 0.4 1.7e-35 121.6 0.1 3.3 3 0 0 3 3 3 1 Multicopper oxidase Methyltransf_16 PF10294.9 KLO10983.1 - 5e-15 55.7 0.0 7.4e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 KLO10983.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_12 PF08242.12 KLO10983.1 - 0.046 14.5 0.0 0.088 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KLO10983.1 - 0.17 12.6 0.0 0.4 11.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MqsR_toxin PF15723.5 KLO10985.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 2 0 0 2 2 2 0 Motility quorum-sensing regulator, toxin of MqsA PQQ PF01011.21 KLO10986.1 - 2.8e-05 23.8 0.0 0.0014 18.5 0.0 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat KDZ PF18758.1 KLO10987.1 - 9.6e-43 146.4 0.1 1.4e-42 145.9 0.1 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO10987.1 - 8.9e-34 115.9 0.0 1.8e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO10987.1 - 1.7e-05 24.9 0.1 4.3e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KLO10987.1 - 0.002 17.9 0.0 0.0062 16.4 0.0 1.8 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KLO10990.1 - 1.4e-58 198.2 0.0 2.6e-58 197.3 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO10990.1 - 6.2e-30 103.5 0.3 2.6e-29 101.5 0.0 2.1 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CEBP_ZZ PF16366.5 KLO10990.1 - 0.24 11.7 4.1 0.58 10.4 4.1 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF4169 PF13770.6 KLO10991.1 - 0.027 14.7 4.8 0.43 10.9 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) Pex14_N PF04695.13 KLO10991.1 - 0.046 14.4 0.9 0.056 14.1 0.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3583 PF12126.8 KLO10991.1 - 0.41 10.1 3.1 0.46 9.9 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) BTB PF00651.31 KLO10992.1 - 2.1e-06 27.9 0.1 4.1e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO10993.1 - 8.6e-07 29.2 0.0 3.3e-06 27.3 0.1 2.0 2 1 0 2 2 2 1 BTB/POZ domain Pkinase_Tyr PF07714.17 KLO10994.1 - 3e-16 59.5 0.0 4.4e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO10994.1 - 6.8e-14 51.9 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO10995.1 - 0.0058 15.9 0.0 0.0058 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CsgG PF03783.14 KLO10995.1 - 0.26 10.5 0.0 0.3 10.3 0.0 1.0 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG Pkinase PF00069.25 KLO10996.1 - 5.6e-32 111.1 0.0 6.9e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO10996.1 - 7.1e-32 110.7 0.0 9.2e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO10996.1 - 9.8e-05 21.3 0.1 0.00013 20.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO10996.1 - 0.0063 15.9 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO10996.1 - 0.037 13.6 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family He_PIG PF05345.12 KLO10996.1 - 0.17 12.1 1.9 0.44 10.8 1.9 1.6 1 0 0 1 1 1 0 Putative Ig domain APH PF01636.23 KLO10996.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KLO10997.1 - 8.2e-25 87.6 0.0 1.3e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO10997.1 - 9.5e-23 80.9 0.0 1.8e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO10997.1 - 0.05 13.5 0.1 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family BTB PF00651.31 KLO10998.1 - 4.9e-07 30.0 0.0 1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Choline_kinase PF01633.20 KLO10998.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 KLO10999.1 - 7e-32 110.7 0.0 1.2e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO10999.1 - 1.2e-28 100.2 0.0 2.5e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11000.1 - 6.4e-24 84.6 0.0 7.6e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO11000.1 - 8.8e-23 81.0 0.0 1e-22 80.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KLO11000.1 - 0.00078 18.3 0.0 0.001 18.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO11000.1 - 0.065 13.2 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KLO11000.1 - 0.081 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KLO11001.1 - 3.2e-25 88.9 0.0 4.7e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO11001.1 - 4.3e-24 85.3 0.0 1.4e-23 83.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain BAR_3 PF16746.5 KLO11001.1 - 0.16 11.7 0.2 0.3 10.8 0.2 1.4 1 0 0 1 1 1 0 BAR domain of APPL family Pkinase_Tyr PF07714.17 KLO11005.1 - 1.6e-27 96.4 0.0 2.7e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO11005.1 - 6.3e-27 94.6 0.0 1.6e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KLO11006.1 - 2.5e-31 109.0 0.0 2.8e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11006.1 - 3.7e-28 98.5 0.0 4.3e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO11006.1 - 2.3e-06 26.6 0.1 2.9e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO11006.1 - 4.2e-05 23.0 0.0 5.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO11006.1 - 0.0054 16.4 0.0 0.0071 16.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KLO11006.1 - 0.021 14.7 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KLO11006.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KLO11007.1 - 3.2e-51 174.1 0.0 7.8e-26 90.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KLO11007.1 - 6.9e-39 133.8 0.0 1.5e-19 70.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Sec31 PF11549.8 KLO11009.1 - 0.25 11.3 0.8 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein transport protein SEC31 MetW PF07021.12 KLO11012.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Pkinase_Tyr PF07714.17 KLO11013.1 - 1.8e-28 99.5 0.0 2.3e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO11013.1 - 1.3e-27 96.8 0.0 1.7e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO11013.1 - 0.21 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 KLO11014.1 - 0.17 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase AAA_22 PF13401.6 KLO11018.1 - 1.2e-09 38.5 0.0 2.8e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO11018.1 - 1e-07 32.5 0.0 4.2e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KLO11018.1 - 2.2e-06 28.1 0.0 5.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KLO11018.1 - 5.6e-05 23.1 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KLO11018.1 - 0.00014 22.2 0.0 0.00033 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 KLO11018.1 - 0.0022 17.9 0.0 0.0052 16.7 0.0 1.6 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain DUF2075 PF09848.9 KLO11018.1 - 0.0024 17.2 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KLO11018.1 - 0.0095 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.22 KLO11018.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 KLO11018.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KLO11018.1 - 0.027 14.4 0.0 0.064 13.2 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Helicase_RecD PF05127.14 KLO11018.1 - 0.048 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_7 PF12775.7 KLO11018.1 - 0.048 13.2 0.1 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KLO11018.1 - 0.078 13.4 0.0 0.18 12.2 0.0 1.7 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 KLO11018.1 - 0.19 11.6 0.1 0.43 10.5 0.1 1.6 1 0 0 1 1 1 0 NTPase Abhydrolase_3 PF07859.13 KLO11019.1 - 4.2e-22 79.0 0.0 4.5e-21 75.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO11019.1 - 2.6e-14 52.9 0.0 5.9e-14 51.7 0.0 1.5 2 0 0 2 2 2 1 Steryl acetyl hydrolase Pkinase_Tyr PF07714.17 KLO11021.1 - 8.5e-33 113.7 0.0 1.2e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO11021.1 - 4.2e-29 101.7 0.0 1.1e-28 100.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain TTC5_OB PF16669.5 KLO11021.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain ZZ PF00569.17 KLO11030.1 - 8.1e-06 25.6 67.5 0.00029 20.6 7.9 6.6 7 0 0 7 7 7 5 Zinc finger, ZZ type Pkinase PF00069.25 KLO11031.1 - 2e-21 76.5 0.0 2.4e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11031.1 - 3e-19 69.3 0.0 3.9e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KLO11031.1 - 0.013 14.9 0.0 0.032 13.6 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO11031.1 - 0.04 13.8 0.0 0.057 13.3 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KLO11031.1 - 0.042 13.4 0.0 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family PB1 PF00564.24 KLO11032.1 - 9.9e-11 41.4 0.0 2.6e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 PB1 domain ZZ PF00569.17 KLO11032.1 - 7.3e-10 38.5 64.1 0.00015 21.5 6.8 6.4 6 0 0 6 6 6 3 Zinc finger, ZZ type C1_2 PF03107.16 KLO11032.1 - 1.5e-07 31.6 51.9 0.016 15.5 2.4 5.8 5 0 0 5 5 5 5 C1 domain TIP_N PF12457.8 KLO11033.1 - 1.3e-10 41.6 9.8 1.3e-10 41.6 9.8 1.8 1 1 1 2 2 2 1 Tuftelin interacting protein N terminal GCFC PF07842.12 KLO11034.1 - 1.3e-78 264.5 5.3 1.8e-78 264.0 5.3 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KLO11034.1 - 4.5e-14 52.1 1.9 8.7e-14 51.1 1.9 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KLO11034.1 - 2.6e-07 30.6 0.4 7.8e-07 29.1 0.4 1.8 1 0 0 1 1 1 1 G-patch domain DnaJ-X PF14308.6 KLO11035.1 - 1.8e-62 210.6 0.4 1.8e-62 210.6 0.4 2.6 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KLO11035.1 - 2.7e-23 81.9 6.1 8.5e-23 80.3 6.1 1.9 1 0 0 1 1 1 1 DnaJ domain Spidroin_N PF16763.5 KLO11035.1 - 0.0072 16.3 1.0 0.031 14.3 0.0 2.2 2 0 0 2 2 2 1 Major ampullate spidroin 1, spider silk protein 1, N-term IFRD PF05004.13 KLO11035.1 - 0.039 13.1 0.1 0.1 11.7 0.1 1.7 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Ndc1_Nup PF09531.10 KLO11035.1 - 0.28 9.8 5.1 6 5.4 4.1 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup HA PF03457.14 KLO11035.1 - 0.49 10.8 2.2 43 4.6 0.3 3.4 3 0 0 3 3 3 0 Helicase associated domain HTH_32 PF13565.6 KLO11035.1 - 1.1 9.9 5.5 0.53 10.9 0.3 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Metal_resist PF13801.6 KLO11035.1 - 1.2 9.3 11.5 0.49 10.6 0.1 3.2 3 0 0 3 3 3 0 Heavy-metal resistance Aminotran_3 PF00202.21 KLO11036.1 - 2.1e-77 260.5 0.0 2.8e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III MLTR_LBD PF17765.1 KLO11036.1 - 0.19 11.8 0.0 0.32 11.1 0.0 1.2 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain HECT PF00632.25 KLO11037.1 - 1.6e-76 257.8 0.0 2.3e-76 257.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KLO11037.1 - 0.014 15.4 0.4 0.65 10.1 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Nse4-Nse3_bdg PF15412.6 KLO11037.1 - 0.033 14.3 0.5 0.13 12.3 0.3 2.2 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE F-box-like PF12937.7 KLO11038.1 - 1.1e-08 34.9 0.0 2.7e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO11038.1 - 9.9e-06 25.3 1.9 4e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KLO11038.1 - 0.0027 17.6 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 F-box DIOX_N PF14226.6 KLO11039.1 - 7.2e-17 62.2 0.0 1.2e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO11039.1 - 3.2e-13 50.0 0.0 5.7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KLO11040.1 - 3e-17 63.5 0.0 5.7e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO11040.1 - 6e-13 49.1 0.0 1.8e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ZapC PF07126.12 KLO11040.1 - 0.23 11.1 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Cell-division protein ZapC FGGY_N PF00370.21 KLO11041.1 - 2.5e-25 89.5 0.1 9.5e-16 58.1 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KLO11041.1 - 7.8e-20 71.5 0.0 3.7e-19 69.2 0.0 2.2 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KLO11041.1 - 0.084 12.4 0.0 11 5.5 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family BTB PF00651.31 KLO11042.1 - 0.00012 22.3 0.0 0.43 10.8 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain zf-H2C2_2 PF13465.6 KLO11042.1 - 0.064 13.7 2.1 0.15 12.5 2.1 1.6 1 0 0 1 1 1 0 Zinc-finger double domain BTB PF00651.31 KLO11043.1 - 0.006 16.8 0.0 6.5 7.0 0.0 2.7 3 0 0 3 3 3 2 BTB/POZ domain HORMA PF02301.18 KLO11044.1 - 2.3e-10 40.4 0.4 4.9e-10 39.4 0.4 1.6 1 1 0 1 1 1 1 HORMA domain ACC_central PF08326.12 KLO11045.1 - 4.7e-242 805.4 0.0 6.2e-242 805.0 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KLO11045.1 - 8.7e-170 565.6 0.0 1.1e-169 565.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KLO11045.1 - 4.5e-49 166.8 0.1 8.1e-49 166.0 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KLO11045.1 - 2.2e-30 105.5 0.1 4.8e-30 104.3 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KLO11045.1 - 3e-21 75.5 0.0 2.6e-19 69.3 0.0 3.4 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KLO11045.1 - 1.6e-12 47.1 0.2 5.1e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KLO11045.1 - 0.0005 20.1 0.3 0.0082 16.2 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KLO11045.1 - 0.011 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF1804 PF08822.11 KLO11045.1 - 0.14 12.2 2.9 0.42 10.6 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) AAA PF00004.29 KLO11046.1 - 4.3e-42 143.7 0.0 8.8e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KLO11046.1 - 1.4e-13 50.4 0.1 3.5e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KLO11046.1 - 2.4e-09 37.0 1.2 3.1e-09 36.7 0.1 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KLO11046.1 - 1.1e-07 32.4 0.2 0.00014 22.3 0.1 3.5 2 1 2 4 4 4 1 AAA ATPase domain AAA_5 PF07728.14 KLO11046.1 - 3.2e-07 30.4 0.2 4.1e-06 26.8 0.1 2.7 3 1 0 3 3 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KLO11046.1 - 1.1e-05 25.6 0.0 4e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KLO11046.1 - 1.3e-05 25.0 0.0 3.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KLO11046.1 - 0.00029 21.1 0.1 0.0044 17.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KLO11046.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KLO11046.1 - 0.0014 19.2 0.0 0.0058 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KLO11046.1 - 0.0032 16.9 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KLO11046.1 - 0.0033 17.0 0.0 0.007 15.9 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 KLO11046.1 - 0.0036 17.5 0.1 0.02 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KLO11046.1 - 0.0052 16.8 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KLO11046.1 - 0.0056 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KLO11046.1 - 0.0062 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KLO11046.1 - 0.0073 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Prot_ATP_OB_N PF17758.1 KLO11046.1 - 0.012 15.2 0.1 0.05 13.3 0.0 2.0 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_30 PF13604.6 KLO11046.1 - 0.013 15.2 0.1 0.037 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KLO11046.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KLO11046.1 - 0.016 15.0 0.0 0.061 13.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 KLO11046.1 - 0.016 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KLO11046.1 - 0.022 14.1 1.9 0.18 11.1 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 KLO11046.1 - 0.025 14.8 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KLO11046.1 - 0.026 14.0 0.1 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 KLO11046.1 - 0.027 14.5 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KLO11046.1 - 0.055 12.6 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KLO11046.1 - 0.062 12.9 0.4 0.17 11.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KLO11046.1 - 0.077 12.9 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KLO11046.1 - 0.1 12.9 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KLO11046.1 - 0.14 11.9 0.4 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain WSC PF01822.19 KLO11047.1 - 6.7e-33 112.7 35.9 1.1e-17 64.0 12.1 3.5 3 0 0 3 3 3 2 WSC domain Glyoxal_oxid_N PF07250.11 KLO11047.1 - 1.8e-26 92.8 0.0 5.9e-25 87.8 0.0 2.6 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KLO11047.1 - 6.2e-23 80.9 0.0 1.2e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KLO11047.1 - 0.025 14.6 0.1 32 4.6 0.0 3.6 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.15 KLO11047.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.8 6 0 0 6 6 6 0 Kelch motif Toxin_3 PF00537.18 KLO11047.1 - 3 8.1 7.5 1.1 9.5 1.1 2.9 2 0 0 2 2 2 0 Scorpion toxin-like domain WSC PF01822.19 KLO11048.1 - 1.3e-35 121.4 34.2 2.9e-20 72.2 14.3 3.7 3 1 1 4 4 4 2 WSC domain SOG2 PF10428.9 KLO11048.1 - 3.4 6.8 21.0 5.5 6.1 21.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 KLO11048.1 - 4.6 6.0 18.8 6.3 5.5 18.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GFO_IDH_MocA PF01408.22 KLO11049.1 - 5.7e-22 78.8 0.0 1.4e-21 77.6 0.1 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold phage_tail_N PF08400.10 KLO11049.1 - 0.026 14.5 0.0 0.078 13.0 0.0 1.8 2 0 0 2 2 2 0 Prophage tail fibre N-terminal RCC1 PF00415.18 KLO11054.1 - 3e-18 66.2 5.7 0.00017 22.1 0.0 6.4 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KLO11054.1 - 1e-13 50.7 19.7 7.5e-07 28.8 0.6 5.8 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 KLO11054.1 - 2.1e-06 27.5 0.1 4.3e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO11054.1 - 0.0056 16.5 0.6 0.024 14.5 0.6 2.1 1 1 0 1 1 1 1 F-box domain Hira PF07569.11 KLO11054.1 - 0.45 10.2 1.3 6.7 6.4 0.1 2.9 3 1 0 3 3 3 0 TUP1-like enhancer of split SWM_repeat PF13753.6 KLO11055.1 - 0.049 13.8 1.2 0.091 12.9 0.1 2.0 2 1 0 2 2 2 0 Putative flagellar system-associated repeat CE2_N PF17996.1 KLO11057.1 - 0.0093 15.9 0.1 0.021 14.8 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal zf-C3HC4 PF00097.25 KLO11058.1 - 2.2e-05 24.2 14.1 5e-05 23.1 14.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KLO11058.1 - 0.00024 21.2 9.1 0.00045 20.3 9.1 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KLO11058.1 - 0.0025 18.1 15.7 0.0059 16.9 15.7 1.7 1 0 0 1 1 1 1 Ring finger domain Tmpp129 PF10272.9 KLO11058.1 - 0.0082 15.5 5.1 0.013 14.9 5.1 1.2 1 0 0 1 1 1 1 Putative transmembrane protein precursor zf-C3HC4_2 PF13923.6 KLO11058.1 - 0.013 15.3 14.5 0.2 11.5 14.5 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO11058.1 - 0.036 14.1 9.1 0.036 14.1 9.1 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 KLO11058.1 - 0.037 14.0 10.6 0.12 12.4 10.7 1.9 1 1 0 1 1 1 0 zinc-RING finger domain DUF3552 PF12072.8 KLO11058.1 - 0.095 12.1 7.6 0.16 11.4 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) zf-C3HC4_4 PF15227.6 KLO11058.1 - 0.18 12.0 14.2 1.2 9.4 14.2 2.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KLO11058.1 - 0.24 11.7 11.8 0.95 9.8 11.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C2H2 PF00096.26 KLO11064.1 - 0.014 15.8 0.5 0.029 14.8 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 KLO11064.1 - 0.016 15.8 0.2 0.022 15.4 0.2 1.3 1 0 0 1 1 1 0 FOXP coiled-coil domain DUF2110 PF09883.9 KLO11064.1 - 0.063 12.9 0.0 0.07 12.7 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) RCC1 PF00415.18 KLO11069.1 - 4.8e-18 65.5 6.4 0.00024 21.7 0.1 6.7 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KLO11069.1 - 4.3e-17 61.4 12.3 1.2e-07 31.4 0.2 4.8 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 KLO11069.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO11069.1 - 0.0069 16.2 0.1 0.015 15.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain TRSP PF12500.8 KLO11069.1 - 0.18 11.7 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 TRSP domain C terminus to PRTase_2 Elongin_A PF06881.11 KLO11069.1 - 0.19 12.3 0.0 0.39 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A WD40 PF00400.32 KLO11071.1 - 2.1e-34 116.9 26.9 5.2e-08 33.4 0.0 12.6 12 0 0 12 12 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO11071.1 - 3.1e-25 88.3 0.0 0.0018 18.6 0.0 9.7 3 3 8 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KLO11071.1 - 6.1e-08 32.8 0.0 1.4e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO11071.1 - 4.3e-07 30.5 0.5 2.2e-06 28.2 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain Ge1_WD40 PF16529.5 KLO11071.1 - 5.1e-07 29.0 0.2 0.26 10.2 0.0 6.0 3 3 4 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA PF00004.29 KLO11071.1 - 8.9e-05 22.9 0.0 0.00028 21.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Nbas_N PF15492.6 KLO11071.1 - 0.00021 20.7 2.1 0.092 12.1 0.1 5.2 6 3 1 7 7 7 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KLO11071.1 - 0.0012 17.6 0.0 0.019 13.6 0.0 2.8 3 1 0 3 3 3 1 Nucleoporin Nup120/160 Zeta_toxin PF06414.12 KLO11071.1 - 0.0023 17.2 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin PD40 PF07676.12 KLO11071.1 - 0.0046 16.8 1.0 40 4.3 0.0 5.8 6 0 0 6 6 5 0 WD40-like Beta Propeller Repeat AAA_22 PF13401.6 KLO11071.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KLO11071.1 - 0.018 15.5 0.0 0.07 13.5 0.0 2.0 2 0 0 2 2 1 0 RNA helicase NB-ARC PF00931.22 KLO11071.1 - 0.035 13.3 0.1 0.068 12.3 0.1 1.5 1 1 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 KLO11071.1 - 0.048 13.4 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 KLO11071.1 - 0.074 12.3 1.3 2 7.6 0.2 2.2 1 1 0 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.20 KLO11071.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.9 KLO11071.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PH PF00169.29 KLO11072.1 - 4.7e-07 30.3 0.0 1.4e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 PH domain APH PF01636.23 KLO11073.1 - 5.8e-14 52.6 0.0 8.3e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KLO11073.1 - 0.00015 21.4 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KLO11073.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RAG2 PF03089.14 KLO11073.1 - 0.23 10.4 0.0 0.33 9.9 0.0 1.1 1 0 0 1 1 1 0 Recombination activating protein 2 Kri1 PF05178.12 KLO11074.1 - 1.5e-23 83.3 11.5 1.5e-23 83.3 11.5 6.8 8 1 0 8 8 8 1 KRI1-like family Kri1_C PF12936.7 KLO11074.1 - 7.1e-22 77.4 0.0 7.1e-22 77.4 0.0 4.7 4 1 1 5 5 5 1 KRI1-like family C-terminal Peptidase_S8 PF00082.22 KLO11075.1 - 7.3e-35 120.7 6.7 1.2e-34 119.9 6.7 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KLO11075.1 - 4e-09 37.0 0.0 7.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Response_reg PF00072.24 KLO11076.1 - 4.7e-23 81.5 0.0 1.4e-17 63.9 0.1 2.0 1 1 1 2 2 2 2 Response regulator receiver domain ER_lumen_recept PF00810.18 KLO11079.1 - 8.8e-56 188.8 7.4 1.3e-55 188.3 7.4 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KLO11079.1 - 0.00092 18.9 6.1 2.1 8.1 0.0 3.9 3 1 1 4 4 4 3 PQ loop repeat Transp_cyt_pur PF02133.15 KLO11080.1 - 2.2e-161 537.5 40.8 2.5e-161 537.3 40.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SAYSvFN PF10260.9 KLO11080.1 - 1.1 9.2 5.5 2 8.4 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) HEAT_EZ PF13513.6 KLO11081.1 - 2.1e-26 92.0 13.4 7.3e-15 55.1 0.0 9.2 7 2 2 9 9 9 3 HEAT-like repeat HEAT PF02985.22 KLO11081.1 - 1.9e-16 58.8 22.9 1.6e-05 24.7 0.0 10.1 12 0 0 12 12 8 5 HEAT repeat HEAT_2 PF13646.6 KLO11081.1 - 6.7e-16 58.5 0.2 0.00016 22.0 0.0 6.8 5 2 3 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KLO11081.1 - 6.6e-09 36.2 0.0 0.019 15.5 0.0 4.1 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KLO11081.1 - 2e-06 28.0 0.1 1.5 8.8 0.0 4.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KLO11081.1 - 0.00067 19.8 0.0 0.017 15.3 0.0 3.2 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 KLO11081.1 - 0.00078 19.1 0.1 2 7.9 0.1 3.4 3 2 1 4 4 4 2 Tti2 family Arm PF00514.23 KLO11081.1 - 0.00096 19.1 1.1 0.66 10.1 0.0 5.1 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 KLO11081.1 - 0.0012 18.7 2.4 5.7 6.9 0.1 4.6 5 0 0 5 5 5 2 Domain of unknown function (DUF3437) Adaptin_N PF01602.20 KLO11081.1 - 0.0015 17.2 0.6 0.08 11.5 0.0 3.0 3 0 0 3 3 3 1 Adaptin N terminal region IBN_N PF03810.19 KLO11081.1 - 0.0019 18.0 0.0 0.0063 16.4 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cohesin_HEAT PF12765.7 KLO11081.1 - 0.079 13.3 1.3 20 5.6 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion FSH1 PF03959.13 KLO11082.1 - 4e-55 186.7 0.0 4.6e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KLO11082.1 - 0.012 15.2 0.0 6.3 6.4 0.0 2.4 3 0 0 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KLO11082.1 - 0.038 13.8 1.0 0.48 10.2 0.5 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KLO11082.1 - 0.045 13.0 0.1 0.66 9.2 0.0 2.4 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Mito_carr PF00153.27 KLO11083.1 - 1.3e-63 211.0 1.6 3.3e-20 71.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein YqjK PF13997.6 KLO11084.1 - 0.12 12.6 2.2 0.13 12.6 1.0 1.6 2 0 0 2 2 2 0 YqjK-like protein Fungal_trans PF04082.18 KLO11085.1 - 4e-17 62.1 0.0 7.7e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO11085.1 - 7.9e-05 22.7 14.9 0.00014 21.9 14.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGDG_synth PF06925.11 KLO11086.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase But2 PF09792.9 KLO11087.1 - 0.065 13.6 0.0 0.24 11.8 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.8 KLO11088.1 - 1e-11 45.1 5.2 5e-11 42.8 5.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PrgH PF09480.10 KLO11088.1 - 0.027 13.8 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) Stimulus_sens_1 PF13756.6 KLO11089.1 - 0.12 12.9 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Stimulus-sensing domain DUF3328 PF11807.8 KLO11090.1 - 1.6e-11 44.4 0.0 4e-11 43.1 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) VHL_C PF17211.3 KLO11090.1 - 0.42 10.7 3.5 2.4 8.2 0.1 2.8 3 0 0 3 3 3 0 VHL box domain Acetyltransf_7 PF13508.7 KLO11091.1 - 3.1e-07 30.7 0.1 1.4e-05 25.4 0.1 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO11091.1 - 1e-06 29.0 0.0 2.2e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KLO11091.1 - 6e-06 26.2 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KLO11091.1 - 0.043 13.5 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 KLO11091.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.7 KLO11092.1 - 6.1e-09 35.9 0.0 9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO11092.1 - 2.4e-08 34.3 0.1 1.9e-07 31.4 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO11092.1 - 2.7e-07 30.8 0.0 4e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KLO11092.1 - 0.00038 20.5 0.1 0.0018 18.4 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KLO11092.1 - 0.014 15.5 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 KLO11092.1 - 0.04 13.9 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein SNF2_N PF00176.23 KLO11093.1 - 4e-63 213.2 0.3 6.4e-63 212.6 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO11093.1 - 3.6e-18 65.9 0.2 1.4e-16 60.8 0.1 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO11093.1 - 7.1e-08 32.6 0.0 1.6e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 KLO11093.1 - 0.013 15.8 1.6 0.074 13.4 1.6 2.5 1 0 0 1 1 1 0 HSA Pkinase PF00069.25 KLO11095.1 - 6e-70 235.6 0.0 7.1e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11095.1 - 3.4e-37 128.1 0.0 4.4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KLO11095.1 - 0.075 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KLO11095.1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DnaJ PF00226.31 KLO11096.1 - 8.4e-12 45.0 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain FGase PF05013.12 KLO11096.1 - 0.11 12.8 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase Totivirus_coat PF05518.11 KLO11096.1 - 6.3 4.7 5.7 8.9 4.2 5.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein Yippee-Mis18 PF03226.14 KLO11097.1 - 3.1e-09 37.0 0.0 4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Syja_N PF02383.18 KLO11099.1 - 4.6e-76 256.2 0.0 7.1e-76 255.6 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Glyco_hydro_43 PF04616.14 KLO11100.1 - 4.4e-67 226.4 0.5 5.5e-67 226.1 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KLO11100.1 - 2e-24 86.5 0.0 3.6e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain XPG_N PF00752.17 KLO11101.1 - 9.8e-34 115.9 0.0 2.1e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KLO11101.1 - 1.1e-29 102.6 0.0 2.8e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KLO11101.1 - 1.2e-07 32.2 0.1 3.4e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KLO11101.1 - 0.025 15.2 0.1 0.091 13.4 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain Fe_dep_repr_C PF02742.15 KLO11101.1 - 0.037 14.1 0.0 0.21 11.7 0.0 2.3 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain NUFIP2 PF15293.6 KLO11101.1 - 2 7.2 12.4 6.7 5.5 7.8 2.1 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 2 Ank_4 PF13637.6 KLO11102.1 - 1.2e-07 32.1 0.8 0.00095 19.7 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) SAP PF02037.27 KLO11102.1 - 0.16 11.7 0.0 0.41 10.4 0.0 1.7 2 0 0 2 2 2 0 SAP domain DUF2263 PF10021.9 KLO11103.1 - 3.5e-24 85.8 0.1 4.9e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) 2-Hacid_dh_C PF02826.19 KLO11104.1 - 5.5e-50 169.2 0.0 7.3e-50 168.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KLO11104.1 - 1.7e-17 63.3 0.0 2.1e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KLO11104.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SWIB PF02201.18 KLO11105.1 - 2.3e-28 97.9 0.2 4.1e-28 97.1 0.2 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KLO11105.1 - 1.1e-07 31.6 0.3 2.4e-07 30.5 0.3 1.6 1 0 0 1 1 1 1 DEK C terminal domain DUF1194 PF06707.11 KLO11105.1 - 0.073 12.3 0.9 0.12 11.6 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) PPTA PF01239.22 KLO11106.1 - 1.9e-08 33.8 16.7 2.2e-06 27.2 0.5 4.4 4 1 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat DUF2615 PF11027.8 KLO11107.1 - 0.08 13.1 0.0 0.094 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Sel1 PF08238.12 KLO11108.1 - 6.2e-28 96.6 24.3 4.1e-05 24.1 0.2 11.1 10 1 0 10 10 10 6 Sel1 repeat RNase_T PF00929.24 KLO11108.1 - 6e-16 59.4 0.0 1.2e-15 58.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease TPR_6 PF13174.6 KLO11108.1 - 0.013 16.1 3.3 1.2e+02 3.7 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 KLO11108.1 - 0.021 15.4 1.9 9.7 6.9 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KLO11108.1 - 0.044 13.7 3.1 0.25 11.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KLO11108.1 - 0.06 13.2 7.2 0.43 10.5 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KLO11108.1 - 0.11 12.7 0.0 0.11 12.7 0.0 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF2890 PF11081.8 KLO11109.1 - 0.91 9.6 8.8 1.1 9.4 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) AKAP7_NLS PF10469.9 KLO11112.1 - 1.8e-11 44.3 0.0 6.5e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain NICE-1 PF15845.5 KLO11113.1 - 0.065 14.0 2.2 0.088 13.6 2.2 1.2 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family FXR_C1 PF16096.5 KLO11113.1 - 0.28 11.4 7.9 0.41 10.9 7.9 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 G-alpha PF00503.20 KLO11114.1 - 2.9e-83 279.9 0.0 4.8e-83 279.3 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO11114.1 - 3.2e-07 30.0 0.0 0.00066 19.2 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KLO11114.1 - 0.0025 18.0 0.0 0.71 10.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KLO11114.1 - 0.016 14.7 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 KLO11114.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KLO11114.1 - 0.21 11.3 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain BTB PF00651.31 KLO11115.1 - 3.2e-06 27.3 0.0 6.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 KLO11115.1 - 0.13 12.4 0.1 0.35 11.1 0.1 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain BAR_3 PF16746.5 KLO11116.1 - 0.052 13.2 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 BAR domain of APPL family BTB PF00651.31 KLO11117.1 - 2.2e-06 27.9 0.0 4.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO11118.1 - 4.8e-08 33.2 0.0 8.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 KLO11118.1 - 0.02 15.0 0.1 0.034 14.3 0.1 1.3 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain ABC_tran PF00005.27 KLO11119.1 - 1.9e-46 158.0 0.0 1.7e-22 80.4 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KLO11119.1 - 1.2e-21 76.5 3.8 1.2e-21 76.5 3.8 2.1 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 KLO11119.1 - 1e-14 55.1 5.6 0.0044 16.9 0.1 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KLO11119.1 - 6.5e-09 35.4 0.5 0.0022 17.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KLO11119.1 - 2.1e-08 33.9 1.3 0.54 9.6 0.1 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KLO11119.1 - 1.1e-07 32.4 0.0 0.011 16.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KLO11119.1 - 7e-07 30.0 9.4 0.024 15.2 0.0 3.9 5 0 0 5 5 3 2 AAA domain NACHT PF05729.12 KLO11119.1 - 1.5e-05 25.0 0.0 0.054 13.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 KLO11119.1 - 8.5e-05 22.6 0.0 0.35 11.0 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 KLO11119.1 - 0.00011 22.0 14.5 0.23 11.1 0.1 4.9 2 2 2 4 4 4 2 AAA ATPase domain AAA_28 PF13521.6 KLO11119.1 - 0.00012 22.4 0.2 0.2 11.9 0.2 2.9 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 KLO11119.1 - 0.00033 20.6 1.1 0.54 10.1 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 KLO11119.1 - 0.00048 20.7 1.4 1 9.9 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KLO11119.1 - 0.0006 20.1 0.3 0.72 10.1 0.0 3.2 2 2 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KLO11119.1 - 0.00082 19.1 0.4 3.6 7.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KLO11119.1 - 0.0018 17.5 0.0 0.46 9.6 0.0 2.5 3 0 0 3 3 2 1 NB-ARC domain DUF87 PF01935.17 KLO11119.1 - 0.0028 17.8 3.6 1.1 9.3 0.1 3.6 4 1 0 4 4 3 2 Helicase HerA, central domain AAA_30 PF13604.6 KLO11119.1 - 0.0049 16.6 0.0 1.6 8.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KLO11119.1 - 0.0055 16.7 0.1 8.2 6.5 0.0 3.8 4 1 1 5 5 3 0 AAA domain RNA_helicase PF00910.22 KLO11119.1 - 0.0069 16.8 2.7 4.8 7.6 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_5 PF07728.14 KLO11119.1 - 0.0086 16.1 0.0 3.2 7.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KLO11119.1 - 0.011 15.3 0.0 7.7 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KLO11119.1 - 0.013 15.7 0.1 4.2 7.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KLO11119.1 - 0.014 14.7 0.2 1.5 8.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 KLO11119.1 - 0.017 15.6 0.3 9.2 6.7 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 KLO11119.1 - 0.027 14.1 0.0 1.6 8.3 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 KLO11119.1 - 0.03 14.5 0.0 14 5.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 KLO11119.1 - 0.036 14.0 2.9 3.2 7.6 0.3 3.2 4 0 0 4 4 3 0 NTPase ATPase_2 PF01637.18 KLO11119.1 - 0.036 14.0 1.2 0.56 10.1 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 KLO11119.1 - 0.043 13.4 0.0 9.5 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KLO11119.1 - 0.045 12.4 5.1 2.3 6.8 0.0 3.6 3 1 0 4 4 4 0 AAA domain G-alpha PF00503.20 KLO11119.1 - 0.046 12.9 0.1 5.2 6.1 0.0 2.8 2 1 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 KLO11119.1 - 0.06 13.1 0.4 7.3 6.3 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MtrA PF04208.14 KLO11119.1 - 0.076 12.6 1.1 0.12 12.0 0.2 1.8 2 0 0 2 2 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A DAP3 PF10236.9 KLO11119.1 - 0.092 11.9 2.3 5.7 6.0 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DivIC PF04977.15 KLO11119.1 - 0.12 12.2 5.6 1.7 8.5 1.5 2.5 2 0 0 2 2 2 0 Septum formation initiator cobW PF02492.19 KLO11119.1 - 0.14 11.7 0.2 4.2 6.9 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain tRNA_m1G_MT PF01746.21 KLO11119.1 - 0.26 10.9 1.5 12 5.6 0.1 3.2 3 1 0 3 3 2 0 tRNA (Guanine-1)-methyltransferase Dynamin_N PF00350.23 KLO11119.1 - 0.33 11.0 9.5 3.9 7.5 0.1 4.4 2 2 1 3 3 3 0 Dynamin family DUF2813 PF11398.8 KLO11119.1 - 0.37 10.0 2.7 6.6 5.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) MFS_1 PF07690.16 KLO11122.1 - 1.1e-22 80.5 40.1 3.9e-22 78.7 39.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Chal_sti_synt_N PF00195.19 KLO11122.1 - 0.09 12.2 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain zf-MYND PF01753.18 KLO11124.1 - 9e-12 44.9 10.3 1.7e-11 44.0 10.3 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO11125.1 - 6.5e-11 42.1 8.9 1.5e-10 41.0 8.9 1.6 1 0 0 1 1 1 1 MYND finger DUF4727 PF15856.5 KLO11125.1 - 0.046 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) G-alpha PF00503.20 KLO11127.1 - 8.7e-103 344.2 0.0 1.4e-102 343.5 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO11127.1 - 1.4e-07 31.2 0.0 1.2e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family EssA PF10661.9 KLO11127.1 - 0.021 14.7 1.4 0.58 10.0 0.2 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA DUF2239 PF09998.9 KLO11127.1 - 0.11 12.2 2.5 0.24 11.2 2.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) Nepo_coat_N PF03689.15 KLO11128.1 - 0.027 14.4 0.0 0.072 13.0 0.0 1.7 2 0 0 2 2 2 0 Nepovirus coat protein, N-terminal domain zf-MYND PF01753.18 KLO11129.1 - 1.1e-07 31.8 16.2 5.1e-07 29.7 16.2 2.1 1 1 0 1 1 1 1 MYND finger DUF836 PF05768.14 KLO11129.1 - 0.33 11.4 0.0 0.33 11.4 0.0 2.5 3 0 0 3 3 3 0 Glutaredoxin-like domain (DUF836) zf-Mss51 PF13824.6 KLO11129.1 - 1.2 9.3 6.3 3 8.0 6.3 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PolC_DP2 PF03833.13 KLO11129.1 - 1.6 6.5 4.6 2.1 6.1 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.18 KLO11130.1 - 1.8e-11 43.9 8.5 3.8e-11 42.9 8.5 1.6 1 0 0 1 1 1 1 MYND finger POTRA_2 PF08479.11 KLO11130.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type Pkinase_Tyr PF07714.17 KLO11131.1 - 8.4e-35 120.3 0.0 9.7e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO11131.1 - 4.4e-29 101.7 0.0 5.1e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO11131.1 - 6.5e-05 23.0 0.1 0.00013 22.0 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KLO11131.1 - 0.00023 20.6 0.0 0.00034 20.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH_6_hur PF04655.14 KLO11131.1 - 0.0062 15.9 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase Kinase-like PF14531.6 KLO11131.1 - 0.023 14.0 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KLO11131.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KLO11132.1 - 8.7e-05 21.9 0.1 0.0001 21.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO11132.1 - 0.0037 16.7 0.0 0.0046 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF1560 PF07597.11 KLO11133.1 - 0.055 13.5 0.4 5.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1560) Sars6 PF12133.8 KLO11136.1 - 0.034 14.1 0.1 0.058 13.3 0.1 1.3 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus V_ATPase_I PF01496.19 KLO11138.1 - 0.31 8.9 0.1 0.41 8.5 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4050 PF13259.6 KLO11138.1 - 6.2 7.1 15.5 1.4 9.2 9.7 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF4050) Pkinase_Tyr PF07714.17 KLO11142.1 - 1.2e-29 103.5 0.0 2.9e-29 102.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KLO11142.1 - 4.1e-29 101.7 0.0 6.2e-28 97.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KLO11142.1 - 0.1 11.9 0.2 0.23 10.8 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO11142.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-MYND PF01753.18 KLO11145.1 - 1.3e-10 41.2 9.9 2.8e-10 40.1 9.9 1.6 1 0 0 1 1 1 1 MYND finger zf-CCHC_2 PF13696.6 KLO11147.1 - 0.0083 15.9 6.4 0.012 15.4 6.4 1.3 1 0 0 1 1 1 1 Zinc knuckle PBP1_TM PF14812.6 KLO11147.1 - 0.0085 16.4 5.5 0.016 15.6 5.5 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KLO11147.1 - 0.05 13.3 1.2 0.094 12.4 1.2 1.4 1 0 0 1 1 1 0 FAM176 family RXLR_WY PF18634.1 KLO11147.1 - 0.07 13.1 0.5 0.14 12.1 0.4 1.5 2 0 0 2 2 2 0 RXLR phytopathogen effector protein WY-domain DUF4611 PF15387.6 KLO11147.1 - 2.6 8.3 13.2 2.1 8.6 8.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 KLO11147.1 - 3 8.3 10.1 5.6 7.4 10.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MULE PF10551.9 KLO11148.1 - 4.5e-05 23.8 0.1 0.00017 21.9 0.1 2.1 1 0 0 1 1 1 1 MULE transposase domain E1-E2_ATPase PF00122.20 KLO11149.1 - 2.2e-45 154.4 0.0 2.2e-45 154.4 0.0 3.2 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KLO11149.1 - 4.4e-36 124.3 2.4 4.4e-36 124.3 2.4 1.8 1 1 1 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KLO11149.1 - 4.1e-19 69.7 0.0 5.9e-09 36.5 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KLO11149.1 - 1.1e-11 44.2 0.0 2.8e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KLO11149.1 - 5.9e-10 39.1 0.0 1.4e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KLO11149.1 - 0.00076 19.3 1.4 0.0016 18.2 0.7 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_3 PF13727.6 KLO11149.1 - 0.015 15.3 1.9 0.8 9.7 1.4 3.0 2 0 0 2 2 2 0 CoA-binding domain RseC_MucC PF04246.12 KLO11149.1 - 0.019 14.9 2.0 0.027 14.4 0.1 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC EI24 PF07264.11 KLO11149.1 - 0.37 11.0 4.8 0.2 11.9 0.9 2.3 2 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) GREB1 PF15782.5 KLO11150.1 - 0.52 7.4 14.6 0.58 7.2 14.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 KLO11150.1 - 0.7 8.4 20.1 0.76 8.3 20.1 1.2 1 0 0 1 1 1 0 Macoilin family Zn_clus PF00172.18 KLO11151.1 - 2.3e-05 24.4 7.3 3.1e-05 24.0 7.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WAC_Acf1_DNA_bd PF10537.9 KLO11151.1 - 0.083 13.4 0.0 0.22 12.1 0.0 1.7 1 1 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal Lar_restr_allev PF14354.6 KLO11151.1 - 0.11 12.9 4.0 0.16 12.4 4.0 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn_clus PF00172.18 KLO11152.1 - 8.5e-05 22.6 8.1 0.00012 22.1 8.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO11153.1 - 3.8e-05 23.7 4.8 5.5e-05 23.2 4.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO11154.1 - 5.7e-07 29.6 14.3 5.7e-07 29.6 14.3 2.3 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4712 PF15830.5 KLO11154.1 - 0.031 14.0 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) DUF4596 PF15363.6 KLO11155.1 - 1.3 9.3 8.6 1.7 8.9 1.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4596) CNP1 PF08750.11 KLO11159.1 - 0.067 13.1 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 CNP1-like family RhoGEF PF00621.20 KLO11160.1 - 2.9e-35 122.2 0.0 4.7e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DUF1048 PF06304.11 KLO11164.1 - 0.085 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) Zn_clus PF00172.18 KLO11165.1 - 0.00036 20.6 8.3 0.0017 18.5 8.2 2.0 1 1 1 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-B_box PF00643.24 KLO11165.1 - 0.026 14.7 3.0 0.059 13.5 3.0 1.6 1 0 0 1 1 1 0 B-box zinc finger Zn_clus PF00172.18 KLO11166.1 - 9e-05 22.5 9.0 0.00019 21.5 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_adjacent PF08191.11 KLO11166.1 - 0.0011 19.1 0.2 0.002 18.3 0.2 1.3 1 0 0 1 1 1 1 LRR adjacent Rrn6 PF10214.9 KLO11166.1 - 0.013 14.0 6.1 0.014 14.0 6.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor LAP1C PF05609.12 KLO11166.1 - 0.16 11.0 8.7 0.18 10.9 8.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) V_ATPase_I PF01496.19 KLO11166.1 - 0.46 8.3 3.7 0.55 8.1 3.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zn_clus PF00172.18 KLO11168.1 - 6e-07 29.5 10.6 8.5e-07 29.0 10.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO11169.1 - 5.7e-07 29.6 9.5 1.1e-06 28.6 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO11174.1 - 0.00029 20.9 10.8 0.00029 20.9 10.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LPG_synthase_TM PF03706.13 KLO11175.1 - 0.016 14.8 7.3 0.024 14.2 7.3 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region DUF3959 PF13105.6 KLO11175.1 - 0.084 12.4 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) UbiA PF01040.18 KLO11175.1 - 0.12 11.6 4.4 0.93 8.7 2.8 2.1 2 0 0 2 2 2 0 UbiA prenyltransferase family CCB1 PF12046.8 KLO11175.1 - 0.16 11.3 0.4 0.31 10.4 0.4 1.5 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B DUF1129 PF06570.11 KLO11175.1 - 0.3 10.5 1.2 0.57 9.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) HMG_box PF00505.19 KLO11176.1 - 7.6 7.0 8.1 0.31 11.5 1.3 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box DUF3584 PF12128.8 KLO11177.1 - 0.0018 15.9 12.9 0.0028 15.3 12.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Prominin PF05478.11 KLO11177.1 - 1.5 6.7 7.8 2.2 6.1 7.8 1.2 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 KLO11177.1 - 4.7 6.0 19.7 13 4.6 19.4 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Transposase_21 PF02992.14 KLO11181.1 - 0.00048 19.4 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 FAM131 PF15010.6 KLO11182.1 - 0.64 9.9 7.0 5.2 6.9 0.1 2.9 1 1 2 3 3 3 0 Putative cell signalling Adeno_E3 PF06040.11 KLO11182.1 - 8.6 6.5 10.2 36 4.5 0.1 4.0 2 1 2 5 5 5 0 Adenovirus E3 protein Zn_clus PF00172.18 KLO11184.1 - 6.3e-05 23.0 7.9 9.8e-05 22.4 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S14 PF00253.21 KLO11184.1 - 0.03 14.1 1.4 0.048 13.4 1.4 1.4 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e TPR_20 PF14561.6 KLO11185.1 - 0.18 12.2 0.0 0.28 11.6 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat SWC7 PF17330.2 KLO11188.1 - 0.056 13.5 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 YihI PF04220.12 KLO11193.1 - 7.2 6.3 5.9 8.6 6.1 0.5 2.6 1 1 2 3 3 3 0 Der GTPase activator (YihI) Aldo_ket_red PF00248.21 KLO11194.1 - 1.8e-70 237.4 0.3 2.1e-70 237.2 0.3 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Potex_coat PF06184.11 KLO11195.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Potexvirus coat protein Pkinase PF00069.25 KLO11196.1 - 6.2e-44 150.3 0.0 8.1e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11196.1 - 6.8e-42 143.5 0.0 8.4e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO11196.1 - 0.00021 20.2 0.0 0.00031 19.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO11196.1 - 0.2 10.9 0.1 2.2 7.5 0.1 2.0 1 1 0 1 1 1 0 Kinase-like F-box-like PF12937.7 KLO11197.1 - 0.0033 17.3 0.5 0.013 15.4 0.1 2.3 2 0 0 2 2 2 1 F-box-like BING4CT PF08149.11 KLO11201.1 - 7.2e-34 115.5 0.0 7e-32 109.1 0.0 2.9 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 KLO11201.1 - 0.00028 21.6 1.6 0.0037 18.1 0.1 3.6 3 1 0 3 3 3 1 WD domain, G-beta repeat YL1_C PF08265.11 KLO11202.1 - 1.7e-12 46.9 0.1 2.8e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CNDH2_C PF16858.5 KLO11202.1 - 0.0048 16.8 0.2 0.005 16.7 0.2 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC27 PF09507.10 KLO11202.1 - 0.057 12.8 6.7 0.068 12.5 6.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1694 PF07997.11 KLO11203.1 - 0.13 12.3 0.0 2.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) Thymopoietin PF08198.11 KLO11203.1 - 0.18 11.5 0.9 12 5.5 0.0 2.3 2 0 0 2 2 2 0 Thymopoietin protein F-box-like PF12937.7 KLO11205.1 - 1.5e-06 28.0 0.0 5.3e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO11205.1 - 0.04 13.8 0.4 1.1 9.2 0.4 2.8 1 1 0 1 1 1 0 F-box domain DUF3420 PF11900.8 KLO11205.1 - 0.075 13.2 0.1 1.6 9.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3420) F-box-like PF12937.7 KLO11206.1 - 1.1e-06 28.4 4.6 3.4e-06 26.8 4.6 1.9 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO11207.1 - 3.3e-07 30.1 0.1 9.4e-07 28.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO11208.1 - 4.3e-07 29.7 0.1 1.2e-06 28.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like Alpha-amylase PF00128.24 KLO11209.1 - 1.2e-119 399.9 0.2 1.7e-119 399.3 0.2 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KLO11209.1 - 0.00014 21.9 0.0 0.00034 20.7 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KLO11209.1 - 0.00073 18.7 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 KLO11209.1 - 0.00084 19.6 0.0 0.0022 18.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) F-box-like PF12937.7 KLO11210.1 - 8.4e-09 35.2 2.0 1e-08 34.9 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO11211.1 - 0.00015 21.6 1.0 0.00028 20.7 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO11212.1 - 0.0018 18.1 0.7 0.0056 16.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO11212.1 - 0.011 16.1 5.9 17 6.0 0.0 4.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO11214.1 - 8.3e-05 22.4 0.2 8.3e-05 22.4 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO11215.1 - 0.00033 20.5 1.7 0.00069 19.5 0.0 2.3 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.7 KLO11216.1 - 0.003 17.4 1.1 0.039 13.8 0.0 3.0 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KLO11216.1 - 0.053 14.0 2.5 1.1 9.8 0.0 4.1 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) p450 PF00067.22 KLO11217.1 - 9.8e-54 182.8 0.0 1.3e-43 149.4 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 PBP PF01161.20 KLO11218.1 - 2.6e-16 60.1 0.0 3e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein F-box-like PF12937.7 KLO11219.1 - 6e-08 32.5 0.6 2.2e-07 30.7 0.6 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO11220.1 - 0.0002 21.2 0.3 0.0023 17.8 0.0 2.7 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO11220.1 - 0.0046 17.3 3.3 1.8 9.1 0.1 4.5 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KLO11220.1 - 0.21 12.2 1.1 76 4.5 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat F-box-like PF12937.7 KLO11221.1 - 0.019 14.9 0.0 0.053 13.4 0.0 1.8 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 KLO11221.1 - 0.14 12.7 6.8 26 5.4 0.1 4.9 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO11222.1 - 0.00021 21.1 3.7 0.00078 19.3 3.7 2.1 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO11222.1 - 0.14 12.7 6.9 0.73 10.3 0.1 4.8 3 1 3 6 6 6 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO11223.1 - 4.2e-06 26.5 0.1 1.5e-05 24.8 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO11224.1 - 4.1e-09 36.2 0.7 2.2e-08 33.9 0.3 2.5 3 0 0 3 3 3 1 F-box-like Cu_bind_like PF02298.17 KLO11227.1 - 0.0001 22.3 0.3 0.72 9.9 0.1 2.9 2 0 0 2 2 2 2 Plastocyanin-like domain Cupredoxin_1 PF13473.6 KLO11227.1 - 0.051 13.7 0.0 4.1 7.6 0.0 3.1 4 0 0 4 4 4 0 Cupredoxin-like domain EF_assoc_1 PF08355.12 KLO11228.1 - 0.15 11.7 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 EF hand associated Polysacc_deac_1 PF01522.21 KLO11229.1 - 8.6e-25 87.0 0.0 3.5e-24 85.1 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase AAA PF00004.29 KLO11230.1 - 5.3e-17 62.5 0.0 1.2e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO11230.1 - 0.00078 19.7 1.1 0.0062 16.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KLO11230.1 - 0.00089 19.3 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KLO11230.1 - 0.0077 16.6 0.1 0.023 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KLO11230.1 - 0.061 13.9 0.0 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KLO11230.1 - 0.12 11.6 0.1 0.31 10.3 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KLO11231.1 - 5.8e-11 42.6 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO11231.1 - 7.4e-06 26.4 0.0 2.8e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO11231.1 - 0.1 12.8 0.0 0.48 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Beta_helix PF13229.6 KLO11233.1 - 2.2e-11 43.9 24.2 1.2e-08 35.0 23.2 3.5 2 1 1 3 3 3 1 Right handed beta helix region NosD PF05048.13 KLO11233.1 - 8.6e-05 21.9 10.4 0.014 14.7 1.5 2.7 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Disaggr_assoc PF08480.10 KLO11233.1 - 0.0012 18.8 9.3 0.27 11.1 1.5 3.2 1 1 1 2 2 2 2 Disaggregatase related Baculo_E56 PF04639.12 KLO11233.1 - 0.0099 15.2 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 1 Baculoviral E56 protein, specific to ODV envelope PAP_central PF04928.17 KLO11234.1 - 2.7e-109 363.9 0.0 3.6e-109 363.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KLO11234.1 - 1.8e-54 184.0 0.0 3.3e-54 183.1 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KLO11234.1 - 2.4e-10 40.6 0.0 6.4e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.6 KLO11234.1 - 0.011 15.9 0.7 0.17 12.1 0.0 3.0 4 0 0 4 4 4 0 DNA polymerase beta palm Nrap_D2 PF17403.2 KLO11234.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Cys_Met_Meta_PP PF01053.20 KLO11235.1 - 2.3e-59 200.9 0.0 5.3e-59 199.7 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme IBN_N PF03810.19 KLO11237.1 - 1.2e-05 25.1 0.1 0.001 19.0 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KLO11237.1 - 0.0066 16.5 0.0 0.034 14.2 0.0 2.2 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.22 KLO11237.1 - 2.4 8.7 4.4 15 6.2 0.2 4.0 4 0 0 4 4 4 0 HEAT repeat Pex2_Pex12 PF04757.14 KLO11238.1 - 1.9e-30 106.1 4.5 2.5e-30 105.8 4.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KLO11238.1 - 0.03 14.2 0.7 0.32 10.9 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO11238.1 - 0.1 12.5 2.9 0.66 9.9 2.9 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mur_ligase_M PF08245.12 KLO11239.1 - 1.1e-05 25.5 0.0 0.0052 16.8 0.0 2.6 1 1 0 1 1 1 1 Mur ligase middle domain Slx4 PF09494.10 KLO11240.1 - 1.2e-09 38.0 0.0 3.5e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Slx4 endonuclease BMF PF15185.6 KLO11240.1 - 0.03 14.0 0.3 3 7.5 0.1 2.3 2 0 0 2 2 2 0 Bcl-2-modifying factor, apoptosis Vps52 PF04129.12 KLO11242.1 - 1.1e-66 225.7 0.7 2.9e-43 148.4 0.2 3.0 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 KLO11242.1 - 9.6e-06 24.3 0.7 9.6e-06 24.3 0.7 1.9 1 1 1 2 2 2 1 Exocyst complex component Sec3 F-box-like PF12937.7 KLO11244.1 - 1.6e-05 24.7 0.0 4.3e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO11246.1 - 8.5e-09 35.2 1.7 8.5e-09 35.2 1.7 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO11246.1 - 0.00051 19.8 0.7 0.003 17.4 0.7 2.2 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO11247.1 - 0.005 16.7 3.0 0.038 13.9 3.0 2.3 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO11248.1 - 0.24 11.3 4.1 1.2 9.1 4.1 2.2 1 1 0 1 1 1 0 F-box-like cNMP_binding PF00027.29 KLO11249.1 - 3.2e-35 120.1 0.1 5.7e-17 61.6 0.0 3.3 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KLO11249.1 - 2e-10 40.2 0.2 5e-10 38.9 0.2 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit fn3 PF00041.21 KLO11250.1 - 0.035 14.5 0.0 6.1 7.3 0.0 3.3 3 0 0 3 3 3 0 Fibronectin type III domain Pkinase_Tyr PF07714.17 KLO11251.1 - 3.6e-31 108.4 0.0 4e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO11251.1 - 3.8e-24 85.5 0.0 4.5e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO11251.1 - 0.00086 19.3 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO11251.1 - 0.0058 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KLO11251.1 - 0.0063 15.9 0.0 0.0076 15.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO11251.1 - 0.0096 14.7 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO11251.1 - 0.032 13.6 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S11 PF00411.19 KLO11252.1 - 1.9e-06 28.2 0.2 4.8e-06 26.9 0.2 1.7 1 1 0 1 1 1 1 Ribosomal protein S11 DUF4657 PF15552.6 KLO11252.1 - 0.024 14.2 1.8 0.032 13.8 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) MAP65_ASE1 PF03999.12 KLO11252.1 - 2.2 6.9 4.0 2.9 6.5 4.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) UCR_UQCRX_QCR9 PF05365.12 KLO11253.1 - 2.4e-27 94.6 4.1 2.7e-27 94.5 4.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like IPK PF03770.16 KLO11254.1 - 4.8e-52 176.7 0.0 9.2e-52 175.8 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase ECR1_N PF14382.6 KLO11256.1 - 2e-15 56.3 0.2 4e-15 55.3 0.2 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KLO11256.1 - 2.9e-13 49.9 0.0 6.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 KH domain F-box-like PF12937.7 KLO11257.1 - 0.00057 19.7 5.1 0.0024 17.7 2.4 2.8 2 1 0 2 2 2 1 F-box-like DNA_methylase PF00145.17 KLO11258.1 - 9.9e-24 84.3 0.0 8.6e-23 81.2 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase fn3 PF00041.21 KLO11258.1 - 0.00055 20.2 6.6 3.5 8.0 0.7 4.6 4 0 0 4 4 4 3 Fibronectin type III domain Methyltransf_15 PF09445.10 KLO11258.1 - 0.0039 16.8 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Pkinase PF00069.25 KLO11260.1 - 2.5e-67 227.0 0.0 3.3e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11260.1 - 9.1e-30 103.8 0.0 1.2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KLO11260.1 - 4e-16 59.5 1.4 1.8e-15 57.4 1.4 2.2 1 1 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 KLO11260.1 - 4.6e-10 39.7 0.1 1.2e-05 25.5 0.1 2.5 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 KLO11260.1 - 1.8e-07 30.8 0.0 1.3e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KLO11260.1 - 2.7e-07 29.9 0.1 4.4e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KLO11260.1 - 0.00093 18.9 0.1 0.15 11.7 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KLO11260.1 - 0.024 14.0 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO11260.1 - 0.034 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Suc_Fer-like PF06999.12 KLO11261.1 - 1.3e-48 165.4 0.0 1.8e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Ribosomal_S18 PF01084.20 KLO11262.1 - 9.5e-15 54.6 0.2 1.9e-14 53.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 Retrotran_gag_2 PF14223.6 KLO11263.1 - 9.7e-08 31.8 0.2 1.4e-07 31.2 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Pkinase PF00069.25 KLO11264.1 - 3.1e-59 200.5 0.0 1.1e-58 198.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11264.1 - 1.6e-27 96.4 0.0 2e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KLO11264.1 - 0.00037 20.5 0.9 0.024 14.6 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO11264.1 - 0.0031 16.9 0.2 0.026 13.8 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KLO11264.1 - 0.0052 16.2 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KLO11264.1 - 0.056 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain UNC-93 PF05978.16 KLO11265.1 - 2.3e-13 50.1 5.1 2.3e-13 50.1 5.1 2.3 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KLO11265.1 - 9.9e-13 47.7 31.4 9.9e-13 47.7 31.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily ABC2_membrane_5 PF13346.6 KLO11265.1 - 4.8 6.7 15.3 0.041 13.4 5.8 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein TB2_DP1_HVA22 PF03134.19 KLO11266.1 - 1.1e-25 89.4 7.0 1.8e-25 88.7 7.0 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ost5 PF05251.12 KLO11267.1 - 9e-19 67.5 11.4 1.1e-18 67.3 11.4 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 TFIIS_C PF01096.18 KLO11268.1 - 1.5e-16 60.0 0.7 1.5e-16 60.0 0.7 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KLO11268.1 - 5e-07 29.5 0.4 5e-07 29.5 0.4 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 KLO11268.1 - 0.0001 22.2 6.5 0.0057 16.7 0.2 2.6 2 1 0 2 2 2 1 Double zinc ribbon DUF523 PF04463.12 KLO11268.1 - 0.00026 21.0 0.4 0.00032 20.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF523) Zn_Tnp_IS1595 PF12760.7 KLO11268.1 - 0.0007 19.5 6.0 0.0022 17.9 0.4 2.7 2 1 1 3 3 3 1 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KLO11268.1 - 0.0011 18.5 8.6 0.0068 15.9 1.1 2.7 2 1 0 2 2 2 1 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 KLO11268.1 - 0.0014 18.5 3.8 0.63 10.0 0.0 3.3 2 2 1 3 3 3 1 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.6 KLO11268.1 - 0.0015 18.4 7.4 3.7 7.5 0.9 3.9 3 1 0 3 3 3 1 zinc-ribbon domain zf-RING_7 PF02591.15 KLO11268.1 - 0.0016 18.6 5.1 2.6 8.3 0.0 4.0 4 0 0 4 4 4 1 C4-type zinc ribbon domain IBR PF01485.21 KLO11268.1 - 0.0042 17.3 7.1 0.041 14.1 0.1 2.7 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain Baculo_LEF5_C PF11792.8 KLO11268.1 - 0.014 15.0 1.3 0.014 15.0 1.3 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain OrfB_Zn_ribbon PF07282.11 KLO11268.1 - 0.02 14.8 8.1 0.67 9.9 0.1 2.6 2 2 0 2 2 2 0 Putative transposase DNA-binding domain zf_UBZ PF18439.1 KLO11268.1 - 0.023 14.3 3.9 5.8 6.6 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger UPF0547 PF10571.9 KLO11268.1 - 0.026 14.6 9.7 2.4 8.3 0.1 3.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Lar_restr_allev PF14354.6 KLO11268.1 - 0.032 14.6 6.4 0.96 9.9 0.4 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-IS66 PF13005.7 KLO11268.1 - 0.039 14.3 7.4 7.9 7.0 0.1 3.3 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-ribbon_3 PF13248.6 KLO11268.1 - 0.048 13.1 12.0 1.5 8.3 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.19 KLO11268.1 - 0.055 13.5 5.4 0.54 10.3 0.1 2.7 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KLO11268.1 - 0.059 13.1 14.7 0.56 10.0 3.6 3.7 3 1 0 3 3 3 0 zinc-ribbon domain SRCR_2 PF15494.6 KLO11268.1 - 0.069 13.7 3.0 0.098 13.2 0.2 2.1 1 1 1 2 2 2 0 Scavenger receptor cysteine-rich domain Paxillin PF03535.13 KLO11268.1 - 0.076 12.9 0.1 0.094 12.6 0.1 1.1 1 0 0 1 1 1 0 Paxillin family Lactamase_B_2 PF12706.7 KLO11268.1 - 0.078 12.5 0.0 0.14 11.6 0.0 1.4 2 0 0 2 2 2 0 Beta-lactamase superfamily domain zf-C2H2_3 PF13878.6 KLO11268.1 - 0.092 12.6 3.3 1.8 8.4 0.0 3.2 2 1 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO Elf1 PF05129.13 KLO11268.1 - 0.15 12.1 7.1 0.072 13.2 1.0 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_9 PF14369.6 KLO11268.1 - 0.2 11.9 9.9 44 4.5 4.2 4.0 3 1 1 4 4 4 0 zinc-ribbon PHD PF00628.29 KLO11268.1 - 0.23 11.4 8.2 2 8.4 0.5 2.9 2 1 1 3 3 3 0 PHD-finger Nudix_N_2 PF14803.6 KLO11268.1 - 0.29 11.1 12.9 0.36 10.8 2.4 3.5 2 2 0 2 2 2 0 Nudix N-terminal UPF0167 PF03691.14 KLO11268.1 - 0.31 10.8 3.5 0.14 11.9 0.7 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) DUF2387 PF09526.10 KLO11268.1 - 0.36 11.0 7.9 3.3 7.9 0.5 2.9 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) DNA_ligase_ZBD PF03119.16 KLO11268.1 - 0.43 10.7 5.7 4.2 7.5 0.3 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DNA_RNApol_7kD PF03604.13 KLO11268.1 - 0.45 10.2 5.9 0.87 9.3 0.5 3.0 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit CpXC PF14353.6 KLO11268.1 - 0.47 10.5 9.8 3.2 7.8 1.4 3.4 1 1 2 3 3 3 0 CpXC protein zf-C4_Topoisom PF01396.19 KLO11268.1 - 0.58 10.0 6.6 14 5.6 0.2 3.5 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-DNL PF05180.12 KLO11268.1 - 0.69 9.9 6.1 0.58 10.1 1.1 3.0 3 1 1 4 4 4 0 DNL zinc finger GFA PF04828.14 KLO11268.1 - 1.2 9.5 8.1 6.5 7.2 0.3 2.7 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-LSD1 PF06943.12 KLO11268.1 - 1.3 8.9 0.0 1.3 8.9 0.0 3.1 3 1 0 3 3 3 0 LSD1 zinc finger HscB_4_cys PF18256.1 KLO11268.1 - 1.4 8.8 0.1 1.4 8.8 0.1 3.4 4 0 0 4 4 4 0 Co-chaperone HscB tetracysteine metal binding motif A2L_zn_ribbon PF08792.10 KLO11268.1 - 1.4 8.7 11.5 2.4 8.0 0.1 3.9 5 0 0 5 5 4 0 A2L zinc ribbon domain Cytochrome_C554 PF13435.6 KLO11268.1 - 1.5 9.8 6.6 2 9.4 1.4 2.1 2 0 0 2 2 2 0 Cytochrome c554 and c-prime zinc_ribbon_13 PF09855.9 KLO11268.1 - 1.6 8.9 8.7 2.5 8.3 0.7 3.0 2 2 1 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Vps36-NZF-N PF16988.5 KLO11268.1 - 1.7 8.1 5.5 7.1 6.1 1.1 2.7 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-LITAF-like PF10601.9 KLO11268.1 - 4 7.8 7.6 12 6.2 1.1 3.4 3 1 1 4 4 3 0 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KLO11268.1 - 4.2 7.6 14.5 9.3 6.5 0.8 3.4 2 2 2 4 4 4 0 Zinc ribbon domain zf-CSL PF05207.13 KLO11268.1 - 8.9 6.1 7.8 1 9.2 0.6 2.3 2 1 0 2 2 2 0 CSL zinc finger Cytochrom_B562 PF07361.11 KLO11269.1 - 0.36 11.5 2.3 0.39 11.4 0.6 1.9 2 0 0 2 2 2 0 Cytochrome b562 Peptidase_M1 PF01433.20 KLO11270.1 - 1e-38 133.1 0.0 1.4e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KLO11270.1 - 2.6e-32 111.3 0.0 5.7e-32 110.1 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KLO11270.1 - 2.5e-17 63.7 0.0 4.1e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 KLO11270.1 - 0.052 14.0 2.2 1.3 9.4 2.2 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_M1 PF01433.20 KLO11271.1 - 2.5e-38 131.8 0.0 3.8e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KLO11271.1 - 7.3e-28 96.9 0.0 1.8e-27 95.7 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KLO11271.1 - 2e-19 70.5 0.1 3.3e-19 69.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 KLO11271.1 - 0.045 14.2 2.0 1.2 9.6 2.0 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase ArfGap PF01412.18 KLO11272.1 - 1.1e-40 138.3 0.4 1.7e-40 137.7 0.4 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf FOXP-CC PF16159.5 KLO11273.1 - 0.18 12.4 0.3 0.5 11.0 0.3 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain DUF629 PF04780.12 KLO11273.1 - 0.19 10.2 0.5 0.29 9.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 KLO11273.1 - 0.22 12.4 0.2 0.53 11.3 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Oxysterol_BP PF01237.18 KLO11274.1 - 4e-85 285.9 1.3 4.8e-83 279.1 1.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Erf4 PF10256.9 KLO11275.1 - 1.4e-29 102.5 0.1 2e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TPR_1 PF00515.28 KLO11276.1 - 1.1e-52 173.8 23.0 1.2e-07 31.2 0.0 10.5 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KLO11276.1 - 4.2e-50 163.9 15.7 3.9e-05 23.4 0.0 10.2 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 KLO11276.1 - 1.6e-39 130.8 7.6 0.00019 21.3 0.0 10.7 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 KLO11276.1 - 3e-30 102.3 5.4 0.004 17.9 0.0 9.4 3 3 6 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 KLO11276.1 - 1.2e-26 93.1 6.4 6e-05 23.6 0.0 7.1 3 2 3 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 KLO11276.1 - 4.1e-25 86.3 12.7 0.00039 20.6 0.0 10.1 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 KLO11276.1 - 2.7e-23 82.2 14.5 0.00012 22.5 0.1 7.2 5 1 2 7 7 7 7 Tetratricopeptide repeat TPR_6 PF13174.6 KLO11276.1 - 3.2e-23 80.8 9.5 0.075 13.7 0.0 9.4 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 KLO11276.1 - 4.8e-23 81.2 14.7 1.8e-05 24.9 0.0 7.1 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 KLO11276.1 - 1.3e-22 79.2 26.2 4.8e-06 26.2 0.4 9.8 5 3 4 9 9 9 6 TPR repeat TPR_7 PF13176.6 KLO11276.1 - 3.3e-22 76.8 7.4 0.025 14.6 0.0 9.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 KLO11276.1 - 1.1e-12 47.9 15.9 0.076 13.2 0.0 6.8 4 2 4 8 8 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO11276.1 - 5.2e-09 36.2 7.9 6e-06 26.4 1.8 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KLO11276.1 - 1.7e-08 34.0 2.8 0.03 13.5 1.7 5.3 1 1 4 6 6 6 2 Tetratricopeptide repeat TPR_21 PF09976.9 KLO11276.1 - 5.4e-05 23.0 3.6 1.1 8.9 0.1 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat-like domain SNAP PF14938.6 KLO11276.1 - 0.00049 19.6 5.9 4.9 6.5 0.0 4.1 1 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP DUF2225 PF09986.9 KLO11276.1 - 0.0067 16.2 0.8 2.7 7.7 0.0 2.8 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.6 KLO11276.1 - 0.0069 16.7 1.6 0.96 9.8 0.1 3.9 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO11276.1 - 0.007 15.8 0.1 0.057 12.8 0.0 2.2 1 1 0 2 2 2 1 MalT-like TPR region RPN7 PF10602.9 KLO11276.1 - 0.049 13.3 2.6 8.5 6.1 0.0 4.1 4 1 1 5 5 5 0 26S proteasome subunit RPN7 TPR_3 PF07720.12 KLO11276.1 - 0.074 13.1 18.1 0.47 10.5 0.4 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat ChAPs PF09295.10 KLO11276.1 - 0.087 11.8 0.1 6.2 5.7 0.0 2.4 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 KLO11276.1 - 0.11 12.6 0.0 42 4.3 0.0 3.8 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.12 KLO11276.1 - 0.11 12.5 0.2 0.77 9.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_10 PF13374.6 KLO11276.1 - 0.2 11.6 16.2 0.28 11.1 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat MIT PF04212.18 KLO11276.1 - 1.5 9.0 15.9 1.4e+02 2.6 3.2 6.3 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain TT_ORF1 PF02956.14 KLO11276.1 - 1.7 7.3 5.4 3.3 6.3 5.4 1.4 1 0 0 1 1 1 0 TT viral orf 1 4F5 PF04419.14 KLO11280.1 - 7.5e-09 36.3 13.1 7.5e-09 36.3 13.1 2.2 1 1 1 2 2 2 1 4F5 protein family DUF2514 PF10721.9 KLO11280.1 - 0.31 11.1 11.6 0.32 11.0 11.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) PAM2 PF07145.15 KLO11282.1 - 0.016 14.8 4.8 12 5.9 0.0 4.2 4 0 0 4 4 4 0 Ataxin-2 C-terminal region DNA_topoisoIV PF00521.20 KLO11283.1 - 1.6e-124 416.1 1.0 2.4e-124 415.5 0.1 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KLO11283.1 - 5.3e-53 178.7 1.0 5.3e-53 178.7 1.0 2.3 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KLO11283.1 - 6.7e-29 100.6 2.3 1.4e-28 99.5 2.3 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KLO11283.1 - 1.5e-12 48.0 0.1 3.9e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KLO11283.1 - 2.3e-08 34.2 0.0 8.3e-08 32.4 0.0 2.0 1 0 0 1 1 1 1 Toprim domain DUF442 PF04273.13 KLO11283.1 - 0.067 13.3 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative phosphatase (DUF442) GFO_IDH_MocA PF01408.22 KLO11284.1 - 6.3e-18 65.7 0.1 1.1e-17 64.9 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KLO11284.1 - 4.8e-16 58.8 0.4 1.8e-15 57.0 0.3 2.0 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KLO11284.1 - 0.014 16.0 0.0 0.026 15.2 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sipho_Gp37 PF14594.6 KLO11284.1 - 0.028 13.4 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein DEAD PF00270.29 KLO11285.1 - 2.7e-42 144.5 0.0 5e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO11285.1 - 2.6e-28 98.6 0.0 2.6e-26 92.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO11285.1 - 8.8e-06 25.8 0.0 4.8e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Nfu_N PF08712.11 KLO11285.1 - 0.097 12.7 0.0 0.4 10.8 0.0 2.1 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal AAA_22 PF13401.6 KLO11285.1 - 0.28 11.4 2.0 3.9 7.8 1.9 2.6 1 1 0 1 1 1 0 AAA domain DUF4969 PF16339.5 KLO11285.1 - 0.64 10.4 3.3 0.93 9.9 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) FAD_binding_3 PF01494.19 KLO11286.1 - 1.8e-18 66.9 0.0 1.4e-17 64.0 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KLO11286.1 - 0.0093 16.2 0.2 0.03 14.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KLO11286.1 - 0.023 13.8 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 KLO11286.1 - 0.03 13.6 0.1 0.11 11.7 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO11286.1 - 0.058 13.0 0.3 0.11 12.0 0.3 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KLO11286.1 - 0.13 11.1 0.4 0.3 9.9 0.0 1.8 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_3 PF01494.19 KLO11287.1 - 2e-23 83.2 0.0 1.6e-22 80.3 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO11287.1 - 0.0016 17.8 0.1 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO11287.1 - 0.0023 18.2 0.1 0.0068 16.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KLO11287.1 - 0.0044 16.1 0.0 0.0072 15.4 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 KLO11287.1 - 0.0067 15.3 1.0 0.17 10.7 0.1 2.5 3 0 0 3 3 3 1 Tryptophan halogenase DAO PF01266.24 KLO11287.1 - 0.025 14.1 0.1 0.071 12.7 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KLO11287.1 - 0.043 14.4 0.1 1.6 9.3 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KLO11287.1 - 0.12 11.4 0.1 1.3 8.0 0.1 2.2 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KLO11287.1 - 0.14 12.1 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding RHD_dimer PF16179.5 KLO11287.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Rel homology dimerisation domain FAD_binding_3 PF01494.19 KLO11288.1 - 5.7e-23 81.7 0.0 2.6e-10 40.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KLO11288.1 - 0.0016 17.7 0.6 0.18 11.0 0.7 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO11288.1 - 0.29 11.4 2.7 0.63 10.3 2.7 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KLO11289.1 - 1e-24 87.5 0.0 9.1e-24 84.3 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KLO11289.1 - 0.0028 16.6 0.1 0.088 11.6 0.0 2.5 2 1 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KLO11289.1 - 0.0087 16.3 0.8 0.022 15.0 0.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO11289.1 - 0.014 14.7 0.0 0.34 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KLO11289.1 - 0.035 13.1 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.6 KLO11289.1 - 0.14 12.2 0.0 21 5.1 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KLO11289.1 - 0.2 11.2 2.0 0.21 11.1 0.7 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase BAR PF03114.18 KLO11290.1 - 2.4e-39 135.4 0.5 4.2e-39 134.6 0.5 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KLO11290.1 - 9.7e-15 53.9 0.1 1.8e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KLO11290.1 - 4.4e-14 52.1 0.2 7.9e-14 51.2 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KLO11290.1 - 7.1e-08 32.0 0.1 1.3e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain FAM76 PF16046.5 KLO11290.1 - 0.25 10.7 2.5 0.14 11.5 0.4 1.6 2 0 0 2 2 2 0 FAM76 protein BAR_3 PF16746.5 KLO11290.1 - 0.28 10.9 5.4 2.4 7.8 5.4 2.3 1 1 0 1 1 1 0 BAR domain of APPL family SBDS PF01172.18 KLO11291.1 - 5.8e-34 116.0 1.4 9.2e-34 115.4 1.4 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 KLO11291.1 - 6.1e-28 97.2 0.7 1e-27 96.4 0.3 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain Pertus-S4-tox PF09275.10 KLO11293.1 - 0.14 12.4 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Pertussis toxin S4 subunit SAP30_Sin3_bdg PF13867.6 KLO11295.1 - 1.2e-05 25.6 0.1 5.4e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Chorismate_synt PF01264.21 KLO11296.1 - 1.1e-140 468.1 0.1 1.2e-140 467.9 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase Nfu_N PF08712.11 KLO11297.1 - 1.5e-29 101.9 0.0 5e-29 100.2 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KLO11297.1 - 1.3e-26 92.5 0.1 3e-26 91.3 0.1 1.6 1 0 0 1 1 1 1 NifU-like domain Glyco_trans_1_4 PF13692.6 KLO11298.1 - 9.3e-06 26.1 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KLO11298.1 - 0.00041 20.8 0.0 0.00086 19.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 KLO11298.1 - 0.0008 19.0 0.0 0.0018 17.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Porphobil_deam PF01379.20 KLO11299.1 - 4.9e-70 235.2 0.0 8e-70 234.5 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KLO11299.1 - 4.7e-16 58.9 0.2 1.1e-15 57.7 0.2 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain ZNRF_3_ecto PF18212.1 KLO11299.1 - 0.046 13.7 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 ZNRF-3 Ectodomain UQ_con PF00179.26 KLO11300.1 - 4.1e-27 94.5 0.0 4.8e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KLO11300.1 - 0.0022 17.7 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KLO11300.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.6 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 KLO11300.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 UEV domain Copper-fist PF00649.18 KLO11301.1 - 3.2e-21 74.5 1.4 3.2e-21 74.5 1.4 3.5 4 0 0 4 4 4 1 Copper fist DNA binding domain DUF1856 PF08983.10 KLO11302.1 - 0.11 12.7 3.1 0.28 11.5 3.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1856) Fe-S_biosyn PF01521.20 KLO11303.1 - 1.2e-21 76.9 0.0 1.6e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis UPF0052 PF01933.18 KLO11305.1 - 1.7e-36 126.0 0.0 3.1e-36 125.1 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 DUF4687 PF15747.5 KLO11305.1 - 0.14 12.7 0.1 0.34 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) SPRY PF00622.28 KLO11306.1 - 6.4e-16 58.6 0.1 8.7e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 SPRY domain sCache_like PF16736.5 KLO11306.1 - 0.082 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Single Cache-like NAD_binding_5 PF07994.12 KLO11307.1 - 0.098 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Homeodomain PF00046.29 KLO11308.1 - 8.2e-43 144.1 8.6 1.1e-13 50.8 1.0 3.3 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 KLO11308.1 - 1.4e-12 47.3 0.2 0.001 18.9 0.0 3.5 3 0 0 3 3 3 3 Homeobox KN domain YdaS_antitoxin PF15943.5 KLO11308.1 - 1.2e-06 28.3 0.4 0.057 13.3 0.1 3.7 4 0 0 4 4 4 2 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 KLO11308.1 - 0.00094 19.2 0.1 1.5 9.0 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix HOCHOB PF17943.1 KLO11308.1 - 0.0059 17.3 0.0 3.2 8.5 0.0 3.1 3 0 0 3 3 3 1 Homeobox-cysteine loop-homeobox LTXXQ PF07813.12 KLO11308.1 - 0.87 10.3 4.3 3.1 8.6 0.5 3.0 3 0 0 3 3 3 0 LTXXQ motif family protein HTH_31 PF13560.6 KLO11308.1 - 1.5 9.3 4.5 9.7 6.6 0.3 3.8 2 1 1 3 3 3 0 Helix-turn-helix domain DUF4598 PF15370.6 KLO11309.1 - 5.8e-17 62.2 8.8 5.8e-17 62.2 8.8 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) PP1_inhibitor PF05361.12 KLO11309.1 - 0.071 13.1 1.2 0.099 12.6 0.4 1.6 2 0 0 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor Macoilin PF09726.9 KLO11309.1 - 0.47 8.9 3.5 0.51 8.8 3.5 1.1 1 0 0 1 1 1 0 Macoilin family SSP160 PF06933.11 KLO11309.1 - 0.58 8.3 16.1 0.81 7.8 16.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Fumble PF03630.14 KLO11311.1 - 3.6e-129 430.7 0.0 1.2e-128 428.9 0.0 1.8 1 1 0 1 1 1 1 Fumble Adaptin_N PF01602.20 KLO11312.1 - 7.1e-116 387.8 0.2 1.8e-115 386.5 0.1 1.6 2 0 0 2 2 2 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KLO11312.1 - 5.3e-57 192.2 1.4 1.2e-56 191.1 1.4 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KLO11312.1 - 1.9e-36 124.7 0.0 5e-36 123.3 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KLO11312.1 - 4.9e-19 68.5 0.8 2e-09 37.7 0.0 6.1 3 2 3 6 6 6 3 HEAT repeats Cnd1 PF12717.7 KLO11312.1 - 2.2e-10 40.8 1.9 0.014 15.4 0.1 4.7 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KLO11312.1 - 5.6e-05 23.0 5.9 2.3 8.7 0.1 6.0 5 0 0 5 5 5 1 HEAT repeat HEAT_PBS PF03130.16 KLO11312.1 - 0.032 14.9 0.1 91 4.2 0.0 4.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 KLO11312.1 - 0.037 14.2 0.3 6.8 6.9 0.0 4.0 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KLO11312.1 - 0.058 13.9 2.7 7.5 7.2 0.0 4.0 3 1 2 5 5 5 0 HEAT-like repeat DUF3385 PF11865.8 KLO11312.1 - 0.12 12.3 1.1 3.1 7.7 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) Arm PF00514.23 KLO11312.1 - 0.15 12.2 2.7 53 4.0 0.0 4.9 6 1 0 6 6 6 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 KLO11313.1 - 2.5e-26 92.6 0.0 3.1e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11313.1 - 7.9e-14 51.6 0.0 1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO11313.1 - 2.3e-09 36.5 0.1 3.3e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO11313.1 - 0.0019 18.2 0.0 0.0069 16.3 0.0 1.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KLO11313.1 - 0.031 13.2 0.1 0.046 12.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KLO11313.1 - 0.12 11.7 0.5 0.19 11.0 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pyr_redox_2 PF07992.14 KLO11314.1 - 1.6e-30 106.3 0.1 2.1e-30 106.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO11314.1 - 3.7e-10 40.2 0.1 3.1e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO11314.1 - 1.3e-06 28.0 3.3 3.7e-05 23.1 0.0 3.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KLO11314.1 - 7.6e-06 25.3 0.0 0.086 12.0 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KLO11314.1 - 5.9e-05 22.8 6.2 0.17 11.4 0.0 4.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KLO11314.1 - 0.00013 21.2 1.0 0.21 10.6 0.0 3.8 3 1 1 4 4 4 1 Lycopene cyclase protein Thi4 PF01946.17 KLO11314.1 - 0.0022 17.3 0.0 0.19 10.9 0.0 2.4 2 0 0 2 2 2 1 Thi4 family SIS PF01380.22 KLO11314.1 - 0.0023 17.8 0.0 0.02 14.8 0.0 2.3 2 0 0 2 2 2 1 SIS domain TrkA_N PF02254.18 KLO11314.1 - 0.0032 17.7 0.0 0.33 11.2 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_9 PF13454.6 KLO11314.1 - 0.0056 16.7 5.1 14 5.7 0.1 4.2 3 1 1 4 4 4 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KLO11314.1 - 0.021 14.1 0.3 0.55 9.4 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 KLO11314.1 - 0.071 11.9 0.8 4.9 5.9 0.1 3.1 4 0 0 4 4 4 0 Tryptophan halogenase HI0933_like PF03486.14 KLO11314.1 - 1.7 7.2 4.0 51 2.4 0.1 3.4 3 1 1 4 4 4 0 HI0933-like protein Homeodomain PF00046.29 KLO11315.1 - 8.9e-13 47.9 2.7 1.7e-12 46.9 2.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KLO11315.1 - 0.011 15.7 0.2 0.024 14.5 0.2 1.5 1 0 0 1 1 1 0 Homeobox KN domain WD40 PF00400.32 KLO11316.1 - 1.3e-20 73.3 12.4 0.004 18.0 0.1 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO11316.1 - 4.7e-08 33.2 0.0 2.9 8.2 0.0 5.9 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_60s PF00428.19 KLO11316.1 - 6.1 7.5 9.7 19 5.9 9.7 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein F-box-like PF12937.7 KLO11317.1 - 1.1e-09 38.0 0.0 3.2e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO11317.1 - 0.0018 18.1 0.9 0.012 15.5 0.9 2.3 1 1 0 1 1 1 1 F-box domain PB1 PF00564.24 KLO11319.1 - 3.6e-09 36.4 0.1 6.5e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 PB1 domain NA37 PF04245.13 KLO11319.1 - 0.016 14.7 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein DUF2604 PF10790.9 KLO11319.1 - 0.088 13.1 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF2604) Abhydrolase_4 PF08386.10 KLO11320.1 - 0.064 13.4 0.0 1.7 8.8 0.0 2.1 2 0 0 2 2 2 0 TAP-like protein Chitin_synth_1 PF01644.17 KLO11323.1 - 1.9e-71 239.3 0.4 3e-71 238.7 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KLO11323.1 - 2e-27 95.0 0.0 5e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KLO11323.1 - 3e-25 88.9 1.6 1e-20 73.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KLO11323.1 - 2e-06 27.9 0.2 2e-06 27.9 0.2 2.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 cNMP_binding PF00027.29 KLO11324.1 - 2.9e-25 88.2 0.0 1.3e-13 50.8 0.0 5.4 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.22 KLO11324.1 - 2.3e-17 63.9 6.5 6.4e-12 46.1 2.9 2.8 3 0 0 3 3 3 2 Patatin-like phospholipase F-box-like PF12937.7 KLO11326.1 - 6.4e-05 22.8 3.0 6.4e-05 22.8 3.0 2.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO11326.1 - 0.00057 19.7 2.2 0.0015 18.4 2.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO11327.1 - 0.00084 19.2 0.1 0.0037 17.1 0.1 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO11327.1 - 0.0075 16.1 0.2 0.0075 16.1 0.2 2.2 2 0 0 2 2 2 1 F-box domain Sec1 PF00995.23 KLO11328.1 - 6.9e-110 369.0 0.0 7.9e-110 368.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Peripla_BP_4 PF13407.6 KLO11328.1 - 0.0057 16.3 0.2 0.75 9.3 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein domain YABBY PF04690.13 KLO11329.1 - 2.6e-12 47.6 0.3 2.6e-12 47.6 0.3 1.1 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 KLO11329.1 - 1.2e-05 25.8 1.6 1.6e-05 25.5 1.6 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 KLO11329.1 - 0.00047 20.5 1.9 0.00069 20.0 1.9 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO11329.1 - 0.0019 18.8 2.1 0.003 18.1 2.1 1.4 1 0 0 1 1 1 1 HMG-box domain F-box-like PF12937.7 KLO11330.1 - 1.7e-05 24.6 0.0 6.2e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO11330.1 - 0.011 15.6 0.1 0.051 13.5 0.0 2.2 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 KLO11330.1 - 0.075 13.5 12.4 28 5.3 0.1 5.8 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) SWI-SNF_Ssr4 PF08549.10 KLO11330.1 - 0.08 11.6 0.3 0.14 10.8 0.3 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) LRR_6 PF13516.6 KLO11330.1 - 0.16 12.1 18.4 2.1 8.6 0.0 6.9 7 1 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 KLO11330.1 - 0.17 12.6 4.8 7.8 7.5 0.4 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat Methyltransf_16 PF10294.9 KLO11331.1 - 1.8e-14 53.8 0.0 3.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KLO11331.1 - 0.024 14.2 0.1 0.099 12.2 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase small domain MFS_1 PF07690.16 KLO11332.1 - 6.7e-19 68.0 17.8 7.6e-18 64.5 17.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Cpn60_TCP1 PF00118.24 KLO11333.1 - 3.1e-154 514.2 0.1 3.6e-154 514.1 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SF3b10 PF07189.11 KLO11334.1 - 7.9e-34 115.6 0.0 9.6e-34 115.3 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Methyltransf_25 PF13649.6 KLO11335.1 - 7.1e-15 55.5 0.0 1.5e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO11335.1 - 3.2e-12 47.0 0.0 6.2e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO11335.1 - 2.6e-09 37.1 0.0 5.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO11335.1 - 2e-08 34.9 0.0 6e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO11335.1 - 3.6e-07 29.8 0.0 6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KLO11335.1 - 5.1e-07 29.6 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KLO11335.1 - 0.00037 19.9 0.0 0.00064 19.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_29 PF03141.16 KLO11335.1 - 0.0019 16.8 0.0 0.003 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.19 KLO11335.1 - 0.0051 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 KLO11335.1 - 0.031 13.9 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 KLO11335.1 - 0.25 10.6 0.0 0.4 9.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Sas10_Utp3 PF04000.15 KLO11336.1 - 8e-19 68.1 0.2 2.2e-18 66.6 0.2 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family HBM PF16591.5 KLO11336.1 - 0.61 9.5 4.2 0.68 9.3 0.5 2.2 2 1 0 2 2 2 0 Helical bimodular sensor domain DUF3176 PF11374.8 KLO11337.1 - 0.00034 20.8 0.5 0.00093 19.4 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) SNF2_N PF00176.23 KLO11338.1 - 1.7e-66 224.4 0.0 2.4e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KLO11338.1 - 1.2e-18 66.8 0.0 4.1e-18 65.1 0.0 1.9 2 0 0 2 2 1 1 HIRAN domain Helicase_C PF00271.31 KLO11338.1 - 7.2e-15 55.3 0.0 2.2e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KLO11338.1 - 3e-08 33.3 9.2 8.1e-07 28.8 9.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO11338.1 - 5.9e-06 26.0 8.9 1.2e-05 25.1 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO11338.1 - 3.8e-05 23.9 8.0 8.1e-05 22.9 8.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KLO11338.1 - 7.1e-05 22.6 5.2 0.00014 21.7 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KLO11338.1 - 8.9e-05 22.5 2.6 0.00011 22.3 0.0 2.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KLO11338.1 - 8.9e-05 22.4 7.1 0.00017 21.5 7.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 KLO11338.1 - 0.00021 21.1 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.6 KLO11338.1 - 0.001 19.1 8.2 0.002 18.1 6.9 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KLO11338.1 - 0.0015 18.6 1.2 0.0035 17.4 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KLO11338.1 - 0.0028 17.8 10.2 0.0059 16.7 10.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.20 KLO11338.1 - 0.04 13.7 4.2 0.077 12.8 4.2 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KLO11338.1 - 0.056 13.3 4.7 0.12 12.2 4.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Patched PF02460.18 KLO11338.1 - 0.08 11.0 0.0 0.13 10.4 0.0 1.2 1 0 0 1 1 1 0 Patched family zf-rbx1 PF12678.7 KLO11338.1 - 0.21 11.9 4.3 0.45 10.8 3.1 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KLO11338.1 - 2.6 7.9 7.1 6 6.7 7.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 KLO11338.1 - 9.2 6.2 9.7 27 4.7 9.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Esterase_phd PF10503.9 KLO11339.1 - 1.9e-26 92.9 0.1 2.9e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 KLO11339.1 - 3.2e-11 43.0 10.6 1e-10 41.4 10.6 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 KLO11339.1 - 1.3e-10 41.1 1.0 1.9e-10 40.6 1.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KLO11339.1 - 0.0044 15.9 0.3 0.0075 15.2 0.3 1.4 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 KLO11339.1 - 0.014 15.1 0.2 0.02 14.5 0.2 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KLO11339.1 - 0.062 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 KLO11340.1 - 1.6e-25 89.9 0.2 2.3e-25 89.4 0.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 KLO11340.1 - 5.4e-12 45.5 9.1 5.4e-12 45.5 9.1 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 KLO11340.1 - 2.7e-11 43.3 1.5 3.8e-11 42.9 1.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KLO11340.1 - 0.0035 16.3 1.1 0.0063 15.4 1.1 1.4 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 KLO11340.1 - 0.012 15.3 0.2 0.016 14.9 0.2 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KLO11340.1 - 0.096 12.5 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KLO11340.1 - 0.33 10.7 1.9 0.36 10.6 0.4 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Zn_clus PF00172.18 KLO11341.1 - 3.5e-08 33.4 5.6 5.3e-08 32.9 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KLO11341.1 - 0.18 11.8 13.8 0.23 11.4 13.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 KLO11341.1 - 0.2 10.6 11.4 0.023 13.7 3.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 KLO11341.1 - 7.6 6.7 24.5 1.6 8.9 11.9 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 BSP PF04450.12 KLO11342.1 - 1.1e-65 221.3 0.0 1.5e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 KLO11342.1 - 0.0041 17.0 0.1 0.0073 16.2 0.1 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 KLO11342.1 - 0.018 15.3 0.1 0.03 14.7 0.1 1.3 1 0 0 1 1 1 0 Effector protein NIF PF03031.18 KLO11343.1 - 3.7e-23 82.0 0.0 2.2e-20 73.0 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 KLO11343.1 - 9.7e-09 35.1 0.4 2.4e-08 33.8 0.4 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KLO11343.1 - 7.7e-05 23.0 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KLO11343.1 - 0.0025 18.1 0.1 0.0065 16.7 0.1 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain adh_short_C2 PF13561.6 KLO11344.1 - 2.3e-22 79.7 0.4 2.8e-22 79.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO11344.1 - 1.4e-13 50.7 0.1 2.1e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 KLO11344.1 - 0.0032 16.8 0.3 0.0047 16.3 0.3 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short_C2 PF13561.6 KLO11345.1 - 1.5e-21 77.1 0.3 5.8e-21 75.1 0.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO11345.1 - 4.5e-12 45.8 0.0 2.8e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NIF3 PF01784.18 KLO11346.1 - 5.5e-65 219.4 0.0 6.8e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RhoGAP PF00620.27 KLO11347.1 - 1.8e-20 73.3 0.0 1.5e-11 44.4 0.0 2.7 3 0 0 3 3 3 2 RhoGAP domain F-box-like PF12937.7 KLO11348.1 - 5.6e-11 42.2 4.1 2.2e-10 40.2 0.4 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO11348.1 - 0.0009 19.1 0.4 0.0009 19.1 0.4 2.3 2 0 0 2 2 2 1 F-box domain DUF3005 PF11448.8 KLO11348.1 - 0.062 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3005) His_Phos_1 PF00300.22 KLO11349.1 - 8.1e-11 42.0 0.0 4.9e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TNRC6-PABC_bdg PF16608.5 KLO11349.1 - 0.084 12.6 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 TNRC6-PABC binding domain Spt5-NGN PF03439.13 KLO11350.1 - 8.6e-13 48.0 0.0 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KLO11350.1 - 4.2e-09 36.0 24.8 0.014 15.4 0.8 5.6 5 0 0 5 5 5 4 KOW motif HAS-barrel PF09378.10 KLO11350.1 - 0.53 10.5 6.3 12 6.1 0.0 3.7 3 1 1 4 4 4 0 HAS barrel domain Spt5_N PF11942.8 KLO11350.1 - 1.8 9.6 7.3 4.7 8.3 7.3 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal F-box-like PF12937.7 KLO11351.1 - 1.9e-07 30.8 0.1 7.4e-07 29.0 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KLO11351.1 - 0.036 14.0 0.1 0.15 12.0 0.0 2.1 1 1 0 1 1 1 0 F-box-like domain p450 PF00067.22 KLO11354.1 - 1.1e-56 192.5 0.0 2.4e-56 191.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KLO11355.1 - 1.8e-08 34.1 0.1 8.7e-08 31.9 0.1 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO11355.1 - 0.12 12.3 1.4 1.4 8.9 1.4 2.7 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO11357.1 - 9.1e-08 31.9 0.6 2.6e-07 30.4 0.6 1.9 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KLO11357.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 KLO11360.1 - 7.8e-07 28.9 0.2 7.8e-07 28.9 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KLO11360.1 - 0.022 14.7 0.1 0.068 13.2 0.1 2.0 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.33 KLO11360.1 - 0.024 14.5 1.5 3.3 7.7 1.2 3.9 2 1 0 2 2 2 0 F-box domain p450 PF00067.22 KLO11363.1 - 4.2e-58 197.2 0.0 6.5e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 KOW PF00467.29 KLO11364.1 - 1.3e-11 44.0 25.6 1.7e-05 24.6 0.3 5.0 5 0 0 5 5 5 4 KOW motif Spt5-NGN PF03439.13 KLO11364.1 - 2.7e-11 43.2 0.0 5.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section IL31 PF15209.6 KLO11366.1 - 0.099 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Interleukin 31 F-box-like PF12937.7 KLO11367.1 - 0.0019 18.1 0.2 0.021 14.7 0.0 2.7 3 0 0 3 3 3 1 F-box-like PhrC_PhrF PF11131.8 KLO11368.1 - 0.069 12.7 0.2 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Rap-phr extracellular signalling F-box-like PF12937.7 KLO11370.1 - 4.5e-09 36.0 0.3 1.2e-08 34.7 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO11370.1 - 0.041 13.8 8.5 0.79 9.7 8.5 2.6 1 1 0 1 1 1 0 F-box domain Epimerase PF01370.21 KLO11371.1 - 6.8e-21 74.8 0.0 1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO11371.1 - 1.2e-13 50.7 0.0 2.7e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KLO11371.1 - 1.1e-12 48.1 0.0 3.4e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KLO11371.1 - 7.8e-12 45.5 0.7 2.2e-11 44.0 0.4 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KLO11371.1 - 9.1e-10 38.1 0.2 1.9e-08 33.8 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KLO11371.1 - 2.8e-05 23.8 0.1 4.5e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KLO11371.1 - 0.00037 19.7 0.1 0.00058 19.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KLO11371.1 - 0.0025 17.3 0.0 0.0065 15.9 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO11371.1 - 0.0026 17.7 0.1 0.0053 16.7 0.1 1.5 1 1 0 1 1 1 1 KR domain COesterase PF00135.28 KLO11372.1 - 2.3e-87 294.0 0.0 2.9e-87 293.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO11372.1 - 9.8e-07 28.8 0.7 7.3e-06 26.0 0.7 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Metallophos PF00149.28 KLO11373.1 - 5e-12 46.8 0.6 1.2e-11 45.5 0.6 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short PF00106.25 KLO11374.1 - 3.7e-26 91.8 0.3 5.3e-26 91.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO11374.1 - 6.1e-21 75.0 0.1 8.7e-21 74.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KLO11374.1 - 1.5e-10 41.3 1.7 9.2e-10 38.7 1.7 2.1 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KLO11374.1 - 4.8e-07 29.9 0.6 1e-06 28.8 0.6 1.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KLO11374.1 - 5.2e-05 22.9 0.8 9.7e-05 22.0 0.8 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KLO11374.1 - 8e-05 22.2 0.1 0.17 11.4 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO11374.1 - 0.00057 19.4 0.1 0.25 10.7 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KLO11374.1 - 0.0021 17.3 1.0 0.018 14.2 0.2 2.6 2 1 0 2 2 2 1 Male sterility protein TrkA_N PF02254.18 KLO11374.1 - 0.053 13.8 0.8 0.11 12.8 0.2 1.8 2 0 0 2 2 2 0 TrkA-N domain DsrH PF04077.12 KLO11374.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 DsrH like protein XFP_N PF09364.10 KLO11375.1 - 1.6e-151 504.3 0.0 2e-151 503.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KLO11375.1 - 1.6e-82 275.9 0.0 3.3e-82 274.9 0.0 1.5 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KLO11375.1 - 9.7e-78 259.9 0.0 1.4e-77 259.3 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 KLO11375.1 - 0.0011 18.8 0.2 0.0038 17.0 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 KLO11375.1 - 0.028 14.3 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain F-box-like PF12937.7 KLO11376.1 - 0.0032 17.3 1.5 0.01 15.7 1.5 1.9 1 0 0 1 1 1 1 F-box-like zf-MYND PF01753.18 KLO11378.1 - 8.1e-12 45.0 22.1 5.9e-10 39.1 7.6 2.9 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.6 KLO11378.1 - 0.15 12.1 9.7 1.1 9.5 1.7 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Siva PF05458.12 KLO11378.1 - 6.1 6.5 10.4 0.22 11.2 3.9 1.8 2 0 0 2 2 2 0 Cd27 binding protein (Siva) zf-MYND PF01753.18 KLO11379.1 - 2.1e-11 43.7 24.8 9.3e-10 38.4 10.4 2.7 2 0 0 2 2 2 2 MYND finger zf-Mss51 PF13824.6 KLO11379.1 - 0.029 14.4 14.7 0.12 12.5 2.0 2.9 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.7 KLO11379.1 - 0.16 13.2 3.1 0.28 12.3 3.1 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins TPR_10 PF13374.6 KLO11380.1 - 1.4e-09 37.5 2.6 0.41 10.6 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat DUF3856 PF12968.7 KLO11380.1 - 3.5e-09 36.9 1.3 0.0069 16.5 0.0 4.1 2 1 2 4 4 4 3 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 KLO11380.1 - 2.2e-07 30.9 13.4 0.062 13.4 0.1 7.3 2 1 5 7 7 7 2 Anaphase-promoting complex subunit 5 AAA_16 PF13191.6 KLO11380.1 - 2.8e-07 31.1 0.1 1.9e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain TPR_12 PF13424.6 KLO11380.1 - 1.6e-06 28.3 6.2 0.35 11.2 0.1 6.4 3 2 4 7 7 7 3 Tetratricopeptide repeat NACHT PF05729.12 KLO11380.1 - 0.00039 20.4 0.4 0.0023 17.8 0.0 2.5 3 0 0 3 3 3 1 NACHT domain TPR_6 PF13174.6 KLO11380.1 - 0.00095 19.6 0.5 4 8.3 0.1 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KLO11380.1 - 0.0069 16.4 2.6 25 5.3 0.2 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA PF00004.29 KLO11380.1 - 0.012 16.0 0.0 0.05 14.0 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) YfiO PF13525.6 KLO11380.1 - 0.034 13.9 0.1 0.091 12.5 0.1 1.7 1 0 0 1 1 1 0 Outer membrane lipoprotein TPR_8 PF13181.6 KLO11380.1 - 0.042 14.1 4.6 20 5.7 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Na_Ca_ex_C PF16494.5 KLO11380.1 - 0.073 13.5 0.8 0.43 11.0 0.4 2.4 1 1 1 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain TPR_4 PF07721.14 KLO11380.1 - 0.26 12.0 0.8 5.3 8.0 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KLO11382.1 - 3.9e-15 55.9 20.2 0.0068 16.7 0.1 9.4 5 3 5 10 10 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 KLO11382.1 - 3.3e-11 42.7 19.2 0.59 10.1 0.0 10.5 11 0 0 11 11 11 2 Tetratricopeptide repeat DUF3856 PF12968.7 KLO11382.1 - 9.3e-10 38.7 15.5 0.0017 18.4 1.6 5.2 3 1 2 6 6 6 5 Domain of Unknown Function (DUF3856) AAA_16 PF13191.6 KLO11382.1 - 1.8e-07 31.7 1.0 1.2e-06 29.1 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KLO11382.1 - 1.7e-05 24.8 0.0 5.3e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KLO11382.1 - 0.0016 18.9 0.1 0.02 15.3 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF4615 PF15393.6 KLO11382.1 - 0.0044 17.6 12.2 9.4 6.8 0.1 6.1 5 1 1 6 6 6 1 Domain of unknown function (DUF4615) NTPase_1 PF03266.15 KLO11382.1 - 0.0061 16.5 0.0 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_5 PF07728.14 KLO11382.1 - 0.0077 16.2 0.0 0.1 12.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) ANAPC5 PF12862.7 KLO11382.1 - 0.013 15.6 27.6 8 6.6 0.1 8.9 4 2 5 9 9 8 0 Anaphase-promoting complex subunit 5 AAA_18 PF13238.6 KLO11382.1 - 0.041 14.4 0.0 0.26 11.8 0.0 2.4 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.12 KLO11382.1 - 0.05 14.1 4.0 0.19 12.2 0.4 3.9 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein TPR_2 PF07719.17 KLO11382.1 - 0.076 13.2 15.1 3.9 7.8 0.0 7.5 9 0 0 9 9 7 0 Tetratricopeptide repeat DUF3874 PF12990.7 KLO11382.1 - 0.12 12.7 1.9 7.8 6.9 0.0 4.5 5 0 0 5 5 4 0 Domain of unknonw function from B. Theta Gene description (DUF3874) AAA_19 PF13245.6 KLO11382.1 - 0.14 12.5 0.1 1.6 9.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain SUKH-4 PF14435.6 KLO11382.1 - 0.17 12.0 0.4 2.5 8.1 0.2 2.7 2 0 0 2 2 2 0 SUKH-4 immunity protein DASH_Dam1 PF08653.10 KLO11382.1 - 0.18 11.6 13.7 23 4.9 0.5 7.6 9 0 0 9 9 7 0 DASH complex subunit Dam1 DUF2075 PF09848.9 KLO11382.1 - 0.21 10.8 0.0 0.21 10.8 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) DUF2175 PF09943.9 KLO11382.1 - 7.3 7.0 8.6 2.5 8.4 0.1 4.3 4 1 1 5 5 4 0 Uncharacterized protein conserved in archaea (DUF2175) BCNT PF07572.12 KLO11384.1 - 4.6e-16 58.6 0.2 4.6e-16 58.6 0.2 1.9 2 0 0 2 2 2 1 Bucentaur or craniofacial development FA_desaturase PF00487.24 KLO11385.1 - 3.2e-15 56.6 19.8 7.4e-15 55.5 19.8 1.6 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KLO11385.1 - 5.8e-12 45.6 0.0 1.3e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-box-like PF12937.7 KLO11386.1 - 0.0012 18.6 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO11386.1 - 0.1 13.0 0.6 3.2 8.3 0.0 3.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Cnd1 PF12717.7 KLO11387.1 - 3.8e-05 23.8 13.9 0.013 15.6 0.0 5.4 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KLO11387.1 - 0.00074 18.2 10.9 0.16 10.5 0.0 4.8 3 2 1 5 5 5 2 Adaptin N terminal region HEAT PF02985.22 KLO11387.1 - 0.0042 17.2 11.9 6.6 7.3 0.0 7.8 9 0 0 9 9 9 1 HEAT repeat Anticodon_1 PF08264.13 KLO11387.1 - 0.0097 15.9 2.6 0.28 11.2 0.0 3.5 4 0 0 4 4 4 1 Anticodon-binding domain of tRNA CLASP_N PF12348.8 KLO11387.1 - 0.011 15.3 9.3 0.93 9.0 0.1 5.5 5 2 2 7 7 7 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 KLO11387.1 - 0.39 11.4 3.4 2.4 8.8 0.9 3.4 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region Xpo1 PF08389.12 KLO11387.1 - 1.5 8.9 9.0 9.1 6.3 0.1 4.7 4 2 1 5 5 5 0 Exportin 1-like protein NARP1 PF12569.8 KLO11388.1 - 9.4e-143 476.8 1.7 6e-138 461.0 0.0 3.0 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KLO11388.1 - 1.7e-14 52.7 10.7 0.0036 17.3 0.1 8.8 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KLO11388.1 - 4.8e-12 45.2 3.3 0.0027 17.5 0.5 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KLO11388.1 - 1.5e-11 44.8 12.1 0.43 11.3 0.1 7.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KLO11388.1 - 1.6e-09 37.2 8.4 0.0085 16.2 0.1 6.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KLO11388.1 - 2.7e-09 37.1 25.2 1.1 10.3 0.1 11.3 8 2 6 14 14 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 KLO11388.1 - 3.2e-09 36.5 0.7 0.42 11.1 0.0 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KLO11388.1 - 3.8e-09 36.9 19.1 0.35 11.4 0.1 8.3 10 1 1 11 11 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KLO11388.1 - 7.9e-09 35.7 5.2 0.12 12.7 0.0 5.4 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KLO11388.1 - 4.4e-07 30.0 10.5 0.077 13.2 0.1 5.8 5 1 1 6 6 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO11388.1 - 2.4e-06 27.6 4.3 0.16 12.2 0.0 5.3 4 2 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KLO11388.1 - 4.5e-06 26.8 8.0 1.2 10.0 0.5 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KLO11388.1 - 8.9e-06 25.3 7.4 0.0049 16.5 0.2 4.6 5 0 0 5 5 5 2 TPR repeat TPR_6 PF13174.6 KLO11388.1 - 0.00033 21.1 13.1 5.7 7.8 0.1 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KLO11388.1 - 0.0013 18.6 12.1 1.5 9.0 0.0 6.5 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO11388.1 - 0.0058 16.0 6.5 0.62 9.4 0.3 3.2 1 1 1 2 2 2 2 MalT-like TPR region MIT PF04212.18 KLO11388.1 - 0.025 14.6 0.4 0.36 10.9 0.1 3.0 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KLO11388.1 - 0.032 14.1 5.8 38 4.3 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4919 PF16266.5 KLO11388.1 - 0.18 11.7 1.0 0.97 9.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) BTAD PF03704.17 KLO11388.1 - 0.39 11.1 7.2 0.085 13.3 1.1 2.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Rapsyn_N PF10579.9 KLO11388.1 - 0.41 10.8 1.7 3.4 7.8 0.0 3.0 3 1 0 3 3 2 0 Rapsyn N-terminal myristoylation and linker region CD225 PF04505.12 KLO11388.1 - 1.2 9.3 0.0 1.2 9.3 0.0 2.2 3 0 0 3 3 2 0 Interferon-induced transmembrane protein Acetyltransf_10 PF13673.7 KLO11389.1 - 1.2e-08 34.9 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO11389.1 - 2.3e-08 34.3 0.0 4.1e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO11389.1 - 1.2e-05 25.5 0.0 1.8e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KLO11389.1 - 4.3e-05 23.4 0.0 0.00035 20.5 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 KLO11389.1 - 0.039 14.1 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KLO11389.1 - 0.059 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase PF00069.25 KLO11390.1 - 3.2e-43 148.0 0.0 1.5e-28 100.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11390.1 - 1.6e-23 83.4 0.0 2.8e-23 82.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO11390.1 - 2.9e-05 23.0 0.0 4.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO11390.1 - 0.0094 15.9 1.4 0.0094 15.9 1.4 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family RNA_binding PF01877.17 KLO11391.1 - 0.067 13.5 0.0 0.081 13.2 0.0 1.1 1 0 0 1 1 1 0 RNA binding DUF4107 PF13389.6 KLO11392.1 - 0.39 10.9 0.1 0.39 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) LtrA PF06772.11 KLO11394.1 - 2.3e-07 30.4 25.4 2.3e-07 30.4 25.4 2.9 2 2 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) ORC3_N PF07034.11 KLO11395.1 - 0.011 14.8 0.8 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus Transp_cyt_pur PF02133.15 KLO11397.1 - 1e-39 136.6 28.4 2.2e-38 132.2 28.4 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin UbiA PF01040.18 KLO11398.1 - 2.4e-15 56.5 14.2 3.5e-15 56.0 14.2 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family UbiA PF01040.18 KLO11399.1 - 1.8e-19 70.1 12.5 2.4e-19 69.6 12.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4177 PF13783.6 KLO11400.1 - 0.085 13.2 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) DUF4177 PF13783.6 KLO11401.1 - 0.02 15.2 0.0 0.079 13.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4177) RRM_1 PF00076.22 KLO11403.1 - 1.6e-18 66.3 0.0 5.8e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBM_35 PF16990.5 KLO11403.1 - 0.18 12.1 0.0 0.64 10.3 0.0 1.8 2 0 0 2 2 2 0 Carbohydrate binding module (family 35) DHC_N2 PF08393.13 KLO11404.1 - 0.00059 19.1 1.3 0.11 11.6 0.2 2.1 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 2 DUF713 PF05218.14 KLO11404.1 - 0.0047 16.7 3.2 0.0069 16.1 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF713) IL31 PF15209.6 KLO11404.1 - 0.084 12.6 0.7 0.17 11.7 0.7 1.6 1 0 0 1 1 1 0 Interleukin 31 BORCS8 PF10167.9 KLO11404.1 - 0.79 9.7 4.4 5.1 7.1 0.4 2.9 1 1 2 3 3 3 0 BLOC-1-related complex sub-unit 8 NPV_P10 PF05531.12 KLO11404.1 - 2.2 8.8 10.2 12 6.4 0.1 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein TPR_10 PF13374.6 KLO11405.1 - 3.1e-29 100.0 2.7 0.00012 21.8 0.0 7.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 KLO11405.1 - 3.2e-17 62.6 0.6 0.0006 20.0 0.0 6.5 5 2 2 7 7 7 3 Tetratricopeptide repeat TcdB_N PF12918.7 KLO11405.1 - 2.3e-09 37.4 0.2 1.4 9.3 0.0 6.2 5 1 1 6 6 6 2 TcdB toxin N-terminal helical domain ANAPC5 PF12862.7 KLO11405.1 - 2.9e-07 30.4 2.2 5.3 7.2 0.2 5.6 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 KLO11405.1 - 8.9e-07 29.2 3.9 11 6.9 0.0 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 KLO11405.1 - 9.2e-07 28.6 2.2 7.3 7.1 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KLO11405.1 - 1.2e-06 28.1 1.0 23 5.4 0.0 6.9 6 2 2 8 8 8 0 Tetratricopeptide repeat DUF3856 PF12968.7 KLO11405.1 - 2e-05 24.7 0.2 2.7 8.1 0.0 3.9 2 2 2 4 4 4 2 Domain of Unknown Function (DUF3856) Sec16_C PF12931.7 KLO11405.1 - 0.003 17.3 2.0 0.16 11.6 0.1 3.5 3 1 2 5 5 5 1 Sec23-binding domain of Sec16 Rif1_N PF12231.8 KLO11405.1 - 0.0091 15.0 0.0 14 4.5 0.0 3.9 1 1 3 5 5 5 0 Rap1-interacting factor 1 N terminal DUF2225 PF09986.9 KLO11405.1 - 0.024 14.3 0.0 24 4.5 0.0 3.4 1 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Tox-MPTase3 PF15639.6 KLO11405.1 - 0.049 13.5 0.1 15 5.4 0.0 3.1 4 0 0 4 4 4 0 Metallopeptidase toxin 3 Na_Ca_ex_C PF16494.5 KLO11405.1 - 0.14 12.7 0.4 10 6.6 0.0 3.4 2 2 1 3 3 3 0 C-terminal extension of sodium/calcium exchanger domain NumbF PF06311.12 KLO11405.1 - 2.1 8.9 4.4 29 5.3 0.0 3.7 3 2 1 4 4 4 0 NUMB domain TPR_17 PF13431.6 KLO11405.1 - 3.3 8.3 5.5 25 5.5 0.1 4.9 6 1 0 6 6 5 0 Tetratricopeptide repeat Pkinase PF00069.25 KLO11408.1 - 8.2e-41 140.1 0.0 1.1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11408.1 - 1.1e-25 90.5 0.0 1.4e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO11408.1 - 7.9e-07 28.7 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO11408.1 - 0.0002 21.4 0.1 0.00033 20.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO11408.1 - 0.017 13.9 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KLO11408.1 - 0.057 12.8 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KLO11408.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase COE1_DBD PF16422.5 KLO11409.1 - 0.053 13.0 0.2 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 Transcription factor COE1 DNA-binding domain HalOD1 PF18545.1 KLO11409.1 - 0.56 10.5 3.1 0.49 10.7 0.5 2.1 2 1 1 3 3 3 0 Halobacterial output domain 1 RPA_interact_M PF14767.6 KLO11409.1 - 0.59 10.7 11.1 1.6 9.3 11.1 1.7 1 0 0 1 1 1 0 Replication protein A interacting middle Cwf_Cwc_15 PF04889.12 KLO11409.1 - 5.1 6.8 24.0 9.4 5.9 14.0 2.1 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein YoeB_toxin PF06769.14 KLO11410.1 - 0.0086 16.1 0.1 0.025 14.6 0.0 1.7 1 1 1 2 2 2 1 YoeB-like toxin of bacterial type II toxin-antitoxin system TPR_10 PF13374.6 KLO11412.1 - 2.2e-57 189.5 4.5 0.00012 21.9 0.0 14.4 14 0 0 14 14 14 12 Tetratricopeptide repeat TPR_12 PF13424.6 KLO11412.1 - 1.2e-37 128.0 13.8 0.011 16.0 0.1 13.5 7 3 6 13 13 13 10 Tetratricopeptide repeat DUF3856 PF12968.7 KLO11412.1 - 1.7e-16 60.6 1.5 0.011 15.8 0.0 6.1 5 1 1 6 6 6 4 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 KLO11412.1 - 1.9e-14 53.5 13.3 2.3 8.3 0.0 13.0 3 1 10 14 14 14 2 Anaphase-promoting complex subunit 5 Rif1_N PF12231.8 KLO11412.1 - 4.4e-14 52.3 0.1 0.21 10.6 0.0 9.4 1 1 8 10 10 10 2 Rap1-interacting factor 1 N terminal TPR_2 PF07719.17 KLO11412.1 - 7.4e-12 44.4 7.5 39 4.7 0.0 13.2 14 1 0 14 14 13 0 Tetratricopeptide repeat AAA_16 PF13191.6 KLO11412.1 - 2.5e-08 34.5 0.0 2.5e-08 34.5 0.0 3.2 3 1 2 5 5 4 1 AAA ATPase domain TPR_6 PF13174.6 KLO11412.1 - 5.4e-08 33.0 19.2 48 4.9 0.0 12.7 14 0 0 14 14 12 0 Tetratricopeptide repeat TPR_8 PF13181.6 KLO11412.1 - 4.4e-06 26.5 13.6 25 5.4 0.2 11.2 13 0 0 13 13 12 0 Tetratricopeptide repeat TPR_14 PF13428.6 KLO11412.1 - 1.1e-05 25.8 20.0 26 6.0 0.0 12.2 8 3 5 13 13 12 0 Tetratricopeptide repeat TPR_4 PF07721.14 KLO11412.1 - 0.00051 20.4 5.0 36 5.4 0.3 6.4 6 0 0 6 6 4 0 Tetratricopeptide repeat Serendipity_A PF05482.12 KLO11412.1 - 0.00084 18.1 4.8 4.7 5.8 0.1 5.6 4 1 2 7 7 7 1 Serendipity locus alpha protein (SRY-A) NACHT PF05729.12 KLO11412.1 - 0.0032 17.4 0.0 0.009 15.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Aida_N PF08910.10 KLO11412.1 - 0.0038 17.6 4.4 36 4.8 0.0 6.6 3 2 1 6 6 6 0 Aida N-terminus NTPase_1 PF03266.15 KLO11412.1 - 0.01 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 NTPase Phage_Treg PF04761.12 KLO11412.1 - 0.023 14.8 0.0 9.2 6.5 0.0 3.3 3 0 0 3 3 3 0 Lactococcus bacteriophage putative transcription regulator AAA_18 PF13238.6 KLO11412.1 - 0.04 14.4 0.0 0.34 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Alpha-E PF04168.12 KLO11412.1 - 0.049 13.4 6.0 9.3 5.9 0.1 4.9 2 1 3 6 6 6 0 A predicted alpha-helical domain with a conserved ER motif. Imm49 PF15575.6 KLO11412.1 - 0.093 12.5 6.7 7.8 6.2 0.0 5.9 5 2 3 8 8 8 0 Immunity protein 49 AAA PF00004.29 KLO11412.1 - 0.1 13.0 0.0 0.38 11.2 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KLO11412.1 - 0.1 11.8 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 KLO11412.1 - 0.14 11.4 0.0 0.32 10.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Syntaxin-6_N PF09177.11 KLO11412.1 - 0.44 11.1 6.4 45 4.7 0.1 5.8 4 2 1 6 6 4 0 Syntaxin 6, N-terminal DEC-1_N PF04625.13 KLO11413.1 - 0.25 10.3 2.1 0.27 10.2 2.1 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RAI1 PF08652.11 KLO11415.1 - 4.1e-22 78.1 0.0 8.1e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Gpi16 PF04113.14 KLO11416.1 - 7.3e-137 457.2 0.0 3.9e-136 454.8 0.0 1.8 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component AAA PF00004.29 KLO11417.1 - 1.9e-86 287.2 0.0 7.3e-42 142.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KLO11417.1 - 2.9e-23 81.4 0.6 3.3e-12 46.0 0.2 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 KLO11417.1 - 4.2e-13 49.5 0.2 2.1e-07 31.0 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KLO11417.1 - 3.6e-11 43.5 0.0 0.00019 21.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KLO11417.1 - 3.5e-10 39.8 0.0 0.0047 16.7 0.0 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KLO11417.1 - 6e-10 39.8 3.8 0.00026 21.4 0.0 5.0 3 2 2 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 KLO11417.1 - 1.5e-09 38.3 0.7 0.0012 19.1 0.1 4.3 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KLO11417.1 - 3.8e-07 30.4 0.0 0.004 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KLO11417.1 - 2.1e-06 27.6 0.0 0.0038 17.0 0.1 2.7 2 1 1 3 3 3 2 IstB-like ATP binding protein TIP49 PF06068.13 KLO11417.1 - 2.1e-05 23.9 0.0 0.078 12.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KLO11417.1 - 0.00013 22.0 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KLO11417.1 - 0.00014 21.9 0.0 0.0083 16.1 0.0 2.8 2 1 1 3 3 3 1 Rad17 P-loop domain Mg_chelatase PF01078.21 KLO11417.1 - 0.00015 21.3 0.4 0.14 11.5 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KLO11417.1 - 0.00015 21.1 0.0 0.036 13.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 KLO11417.1 - 0.00033 20.9 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KLO11417.1 - 0.00035 20.9 0.0 0.47 10.9 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 KLO11417.1 - 0.00035 21.1 0.0 0.14 12.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain Bac_DnaA PF00308.18 KLO11417.1 - 0.00048 20.0 0.0 0.57 10.0 0.0 2.9 3 0 0 3 3 3 1 Bacterial dnaA protein TsaE PF02367.17 KLO11417.1 - 0.00082 19.4 0.0 0.29 11.2 0.0 2.6 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KLO11417.1 - 0.0009 19.1 0.0 5.2 6.9 0.0 3.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KLO11417.1 - 0.001 18.9 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KLO11417.1 - 0.0032 17.1 6.1 1.5 8.3 0.1 4.4 3 2 1 5 5 4 1 AAA domain AAA_7 PF12775.7 KLO11417.1 - 0.0038 16.8 0.0 0.65 9.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 KLO11417.1 - 0.0045 16.8 0.0 0.044 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain CDC48_2 PF02933.17 KLO11417.1 - 0.0064 16.2 0.0 0.055 13.3 0.0 2.4 1 1 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Sigma54_activat PF00158.26 KLO11417.1 - 0.012 15.4 0.0 0.96 9.1 0.0 3.4 2 2 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 KLO11417.1 - 0.012 15.9 0.2 0.21 11.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Ribosomal_L50 PF10501.9 KLO11417.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal subunit 39S ABC_tran PF00005.27 KLO11417.1 - 0.02 15.4 0.0 0.49 10.9 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.6 KLO11417.1 - 0.023 14.8 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KLO11417.1 - 0.03 14.2 0.0 1.6 8.6 0.0 3.1 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KLO11417.1 - 0.034 14.0 0.0 0.43 10.5 0.0 2.7 3 1 0 3 3 3 0 NACHT domain Adeno_IVa2 PF02456.15 KLO11417.1 - 0.051 12.4 0.1 0.82 8.4 0.0 2.3 3 0 0 3 3 2 0 Adenovirus IVa2 protein AAA_30 PF13604.6 KLO11417.1 - 0.062 13.0 0.1 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KLO11417.1 - 0.066 12.4 0.0 0.87 8.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF815) IPT PF01745.16 KLO11417.1 - 0.084 12.2 0.3 3.3 7.0 0.1 2.5 2 0 0 2 2 2 0 Isopentenyl transferase AAA_17 PF13207.6 KLO11417.1 - 0.14 12.6 0.0 3.3 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KLO11417.1 - 0.14 11.2 0.1 0.33 10.0 0.0 1.5 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 ABC_membrane PF00664.23 KLO11418.1 - 3.4e-38 131.9 10.4 4.3e-38 131.5 10.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KLO11418.1 - 1.2e-34 119.7 0.0 2.5e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KLO11418.1 - 4e-07 29.7 0.0 0.00019 20.9 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KLO11418.1 - 0.00022 21.1 0.0 0.00043 20.1 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KLO11418.1 - 0.00053 19.9 0.0 0.048 13.5 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KLO11418.1 - 0.0049 17.3 0.0 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KLO11418.1 - 0.0051 17.2 0.0 0.04 14.4 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KLO11418.1 - 0.0074 16.3 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KLO11418.1 - 0.011 16.0 0.0 0.079 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KLO11418.1 - 0.039 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KLO11418.1 - 0.05 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KLO11418.1 - 0.053 13.4 0.0 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 KLO11418.1 - 0.057 13.7 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KLO11418.1 - 0.077 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_14 PF13173.6 KLO11418.1 - 0.087 12.9 0.0 0.54 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KLO11418.1 - 0.088 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dala_Dala_lig_N PF01820.21 KLO11418.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus AAA_23 PF13476.6 KLO11418.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KLO11418.1 - 0.14 12.7 0.0 0.36 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KLO11418.1 - 0.19 12.0 0.4 2.5 8.4 0.4 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit LRR_4 PF12799.7 KLO11419.1 - 1.6e-21 76.0 26.8 0.00029 21.1 2.5 8.4 6 3 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KLO11419.1 - 4.3e-17 61.6 33.4 3.4e-07 29.9 0.8 9.0 7 2 2 9 9 9 6 Leucine rich repeat LRR_1 PF00560.33 KLO11419.1 - 0.026 15.0 37.0 14 6.7 0.1 10.5 11 1 1 12 12 12 0 Leucine Rich Repeat LRR_6 PF13516.6 KLO11419.1 - 0.066 13.3 35.0 0.82 9.9 0.0 9.3 12 0 0 12 12 12 0 Leucine Rich repeat Acetyltransf_3 PF13302.7 KLO11420.1 - 2.3e-08 34.8 0.0 3.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cyt-b5 PF00173.28 KLO11421.1 - 2e-18 66.3 0.0 2.7e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FYRC PF05965.14 KLO11421.1 - 0.042 14.0 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 F/Y rich C-terminus SUR7 PF06687.12 KLO11423.1 - 4.6e-16 59.1 11.9 2.7e-08 33.7 3.6 2.1 1 1 1 2 2 2 2 SUR7/PalI family Ndc1_Nup PF09531.10 KLO11423.1 - 0.6 8.7 11.5 0.75 8.4 11.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3671 PF12420.8 KLO11423.1 - 0.84 9.7 3.2 4.4 7.4 3.2 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF805 PF05656.14 KLO11423.1 - 1.7 9.1 9.2 29 5.1 9.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Whi5 PF08528.11 KLO11425.1 - 0.16 11.6 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Whi5 like Pkinase_Tyr PF07714.17 KLO11426.1 - 1.1e-49 169.1 0.0 9.5e-33 113.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KLO11426.1 - 6.1e-46 156.9 0.0 3e-27 95.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KLO11426.1 - 2.3e-05 24.5 0.4 0.055 13.4 0.1 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KLO11426.1 - 5.1e-05 23.0 0.0 0.073 12.7 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Seadorna_VP7 PF07387.11 KLO11426.1 - 0.00021 20.5 0.2 0.11 11.5 0.0 2.2 2 0 0 2 2 2 2 Seadornavirus VP7 WaaY PF06176.11 KLO11426.1 - 0.0017 18.0 0.2 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.14 KLO11426.1 - 0.0072 15.7 0.0 0.89 8.9 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KLO11426.1 - 0.045 13.3 0.0 6.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KLO11426.1 - 0.056 12.2 0.0 0.62 8.8 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 KLO11426.1 - 0.12 11.3 0.0 0.35 9.8 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain DUF1679 PF07914.11 KLO11426.1 - 0.22 10.3 0.0 7.7 5.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) BRCT PF00533.26 KLO11427.1 - 0.14 12.6 0.1 2.5 8.5 0.0 2.4 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain STE3 PF02076.15 KLO11428.1 - 1.3e-57 195.3 13.0 1.7e-57 194.9 13.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 KLO11429.1 - 1.2e-54 185.5 16.0 1.5e-54 185.2 16.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor Lon_C PF05362.13 KLO11431.1 - 1.9e-69 233.3 0.1 3.2e-69 232.6 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KLO11431.1 - 1.3e-33 116.6 0.0 3e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KLO11431.1 - 1.6e-21 77.1 0.0 4.1e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KLO11431.1 - 1.4e-07 31.6 0.0 2.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KLO11431.1 - 2.3e-06 27.8 0.0 6e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 KLO11431.1 - 3.1e-05 23.1 0.0 5.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain ChlI PF13541.6 KLO11431.1 - 3.6e-05 23.6 0.1 8.4e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KLO11431.1 - 0.00046 20.6 0.0 0.0016 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KLO11431.1 - 0.00047 19.9 0.0 0.0016 18.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KLO11431.1 - 0.00071 19.9 0.0 0.0079 16.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KLO11431.1 - 0.001 19.4 0.0 0.013 15.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 KLO11431.1 - 0.0091 16.0 0.0 0.034 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KLO11431.1 - 0.021 15.4 0.2 0.079 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DNTTIP1_dimer PF18192.1 KLO11431.1 - 0.034 14.5 0.2 7.3 7.0 0.0 3.0 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain SKI PF01202.22 KLO11431.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 1 0 Shikimate kinase IstB_IS21 PF01695.17 KLO11431.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 KLO11431.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KLO11431.1 - 0.074 13.0 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase SPX PF03105.19 KLO11431.1 - 0.9 9.4 7.2 0.91 9.4 1.9 2.3 2 0 0 2 2 2 0 SPX domain ATXN-1_C PF12547.8 KLO11432.1 - 0.42 11.0 4.7 2.9 8.3 2.6 2.9 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator F-box-like PF12937.7 KLO11434.1 - 0.019 14.8 0.8 0.25 11.3 0.8 2.3 1 1 0 1 1 1 0 F-box-like GalKase_gal_bdg PF10509.9 KLO11436.1 - 2.1e-18 65.6 0.0 4.1e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 KLO11436.1 - 4.2e-12 46.3 0.0 1e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KLO11436.1 - 7.8e-11 42.1 0.9 1.8e-10 40.9 0.9 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain ADH_zinc_N PF00107.26 KLO11437.1 - 3.9e-17 62.4 0.5 7.4e-17 61.6 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO11437.1 - 1.7e-09 37.5 0.0 3.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KLO11437.1 - 2.8e-07 31.6 0.3 7.1e-07 30.3 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KLO11437.1 - 2.2e-06 27.3 0.7 3.6e-06 26.6 0.7 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus CRISPR_Cse1 PF09481.10 KLO11438.1 - 0.01 15.0 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) ADH_zinc_N PF00107.26 KLO11439.1 - 1.5e-17 63.8 0.0 2.9e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO11439.1 - 1.6e-09 39.0 0.0 2.9e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO11439.1 - 7.8e-09 35.4 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KLO11439.1 - 0.002 17.6 0.1 0.0031 17.0 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_2 PF16884.5 KLO11439.1 - 0.03 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Cdc6_C PF09079.11 KLO11440.1 - 0.062 13.3 0.5 1.5 8.8 0.1 2.6 2 1 0 2 2 2 0 CDC6, C terminal winged helix domain ADH_zinc_N PF00107.26 KLO11441.1 - 3.6e-19 69.0 0.1 6.4e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO11441.1 - 1.3e-09 39.2 0.0 2.5e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO11441.1 - 5.1e-08 32.8 0.1 8.6e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KLO11441.1 - 3.3e-05 23.5 0.2 5.3e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus B277 PF17623.2 KLO11444.1 - 0.097 11.7 1.0 0.23 10.5 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function RAP1 PF07218.11 KLO11444.1 - 7 4.8 10.3 18 3.5 10.3 1.6 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) mRNA_triPase PF02940.15 KLO11455.1 - 7e-56 189.4 0.0 8.4e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain TerB PF05099.13 KLO11455.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TerB CRAL_TRIO PF00650.20 KLO11456.1 - 3.2e-30 105.0 0.0 4.8e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KLO11456.1 - 1e-07 32.0 0.0 2.9e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TFIIF_beta PF02270.15 KLO11456.1 - 0.011 15.8 0.0 0.044 13.9 0.0 2.0 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain Zip PF02535.22 KLO11457.1 - 8.5e-33 114.0 9.1 2.4e-32 112.5 9.1 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Cation_efflux PF01545.21 KLO11457.1 - 2.8e-05 24.0 0.4 0.00056 19.7 0.0 2.4 1 1 1 2 2 2 1 Cation efflux family DNA_ligase_OB_2 PF14743.6 KLO11458.1 - 1.1e-30 105.4 0.2 2e-30 104.6 0.2 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 KLO11458.1 - 3.7e-11 43.1 0.0 1e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KLO11458.1 - 2.7e-06 27.8 0.1 1.4e-05 25.5 0.1 2.0 1 1 0 1 1 1 1 RNA ligase GEMIN8 PF15348.6 KLO11458.1 - 0.037 14.3 0.7 0.055 13.8 0.7 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 NOA36 PF06524.12 KLO11458.1 - 3 7.1 8.0 6 6.1 8.0 1.4 1 0 0 1 1 1 0 NOA36 protein TFCD_C PF12612.8 KLO11459.1 - 1.9e-37 129.0 0.0 1.1e-36 126.5 0.0 2.4 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal RTP1_C1 PF10363.9 KLO11459.1 - 0.093 12.9 0.0 5.2 7.3 0.0 3.3 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KLO11459.1 - 0.18 12.1 14.8 0.56 10.6 0.0 6.5 7 0 0 7 7 7 0 HEAT repeat FliT PF05400.13 KLO11459.1 - 4.1 8.3 5.5 9.6 7.1 0.4 3.5 3 0 0 3 3 3 0 Flagellar protein FliT ATP-synt_C PF00137.21 KLO11460.1 - 2.1e-30 104.8 34.8 1e-18 67.4 16.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L6 PF00347.23 KLO11461.1 - 1.5e-17 64.0 0.0 3e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L6 MARVEL PF01284.23 KLO11462.1 - 2.4e-08 34.1 7.3 3.5e-08 33.6 7.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain BUD22 PF09073.10 KLO11465.1 - 1.7e-81 274.8 29.3 2.6e-81 274.2 29.3 1.3 1 0 0 1 1 1 1 BUD22 DUF3813 PF12758.7 KLO11465.1 - 2.6 8.5 7.9 4.9 7.6 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) zf-HIT PF04438.16 KLO11466.1 - 0.84 9.6 11.2 1.6 8.7 11.2 1.4 1 0 0 1 1 1 0 HIT zinc finger F-box-like PF12937.7 KLO11469.1 - 1.1e-07 31.6 0.0 5.5e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO11469.1 - 3.6e-06 26.7 0.1 0.00093 19.0 0.0 3.1 2 0 0 2 2 2 2 F-box domain F-box_4 PF15966.5 KLO11469.1 - 0.048 13.5 0.2 0.8 9.6 0.0 3.0 3 0 0 3 3 3 0 F-box Hormone_3 PF00159.18 KLO11470.1 - 0.04 14.0 0.1 0.04 14.0 0.1 2.2 3 0 0 3 3 3 0 Pancreatic hormone peptide tRNA_bind PF01588.20 KLO11471.1 - 3.7e-27 94.3 0.0 6.3e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 KLO11471.1 - 2.6e-06 27.6 1.2 3.9e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO11471.1 - 4.1e-06 26.9 0.0 9.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KLO11471.1 - 1.9e-05 24.6 0.0 4.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KLO11471.1 - 0.00033 20.4 0.0 0.0047 16.7 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain NARP1 PF12569.8 KLO11471.1 - 0.09 11.7 3.9 0.13 11.2 3.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNA_pol_Rpc4 PF05132.14 KLO11471.1 - 3.1 8.2 8.6 6.3 7.2 8.6 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Scm3 PF10384.9 KLO11472.1 - 3.8e-08 33.0 0.1 3.8e-08 33.0 0.1 2.6 3 0 0 3 3 3 1 Centromere protein Scm3 DPBB_1 PF03330.18 KLO11473.1 - 2.9e-05 24.2 0.0 5.5e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Lytic transglycolase DPBB_1 PF03330.18 KLO11474.1 - 0.0016 18.6 0.0 0.0031 17.7 0.0 1.5 1 1 0 1 1 1 1 Lytic transglycolase F-box-like PF12937.7 KLO11475.1 - 3.5e-07 30.0 0.1 3.5e-07 30.0 0.1 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO11475.1 - 0.061 13.2 1.9 14 5.7 0.1 3.2 3 0 0 3 3 3 0 F-box domain DUF4381 PF14316.6 KLO11475.1 - 0.094 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Nucleoporin_FG2 PF15967.5 KLO11476.1 - 0.07 11.7 0.8 0.083 11.4 0.8 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region PP2C PF00481.21 KLO11478.1 - 1.6e-74 250.8 0.1 5.2e-74 249.1 0.1 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C SDA1 PF05285.12 KLO11478.1 - 1 8.7 5.8 1.7 8.0 5.8 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KLO11478.1 - 1.2 8.3 10.6 2.1 7.6 10.6 1.4 1 0 0 1 1 1 0 BUD22 CS PF04969.16 KLO11479.1 - 3.4e-09 37.6 0.0 1.6e-08 35.4 0.0 2.1 2 0 0 2 2 2 1 CS domain VWA PF00092.28 KLO11480.1 - 6.7e-09 36.2 0.0 1.2e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KLO11480.1 - 7.6e-07 29.7 0.0 2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.8 KLO11480.1 - 0.00021 21.2 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Integrin_beta PF00362.18 KLO11480.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Integrin beta chain VWA domain MSP1_C PF07462.11 KLO11480.1 - 6.1 5.4 5.6 6.1 5.4 3.8 1.8 1 1 1 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Ras PF00071.22 KLO11481.1 - 1.3e-31 109.4 0.0 4.6e-20 71.8 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 KLO11481.1 - 6.4e-29 99.4 0.8 1.1e-28 98.6 0.8 1.4 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.12 KLO11481.1 - 7.2e-28 96.4 0.0 1.9e-27 95.0 0.0 1.8 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 KLO11481.1 - 5.6e-19 68.5 0.0 1.4e-10 41.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 KLO11481.1 - 1.8e-11 43.0 0.4 0.00018 21.2 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KLO11481.1 - 2.9e-10 38.9 3.8 0.00022 20.5 0.2 2.9 3 0 0 3 3 2 2 EF hand EF-hand_7 PF13499.6 KLO11481.1 - 9e-10 38.9 0.2 0.0036 17.7 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain pair Arf PF00025.21 KLO11481.1 - 4.8e-09 35.9 0.0 0.0012 18.3 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KLO11481.1 - 5.8e-08 32.8 0.0 0.00058 19.9 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KLO11481.1 - 2.8e-07 30.9 0.1 0.005 17.1 0.0 3.5 3 1 0 3 3 2 2 AAA domain EF-hand_5 PF13202.6 KLO11481.1 - 4.3e-07 29.1 4.2 0.0085 15.5 0.2 2.7 2 0 0 2 2 2 2 EF hand Dynamin_N PF00350.23 KLO11481.1 - 6.6e-06 26.3 1.2 0.14 12.2 0.0 3.3 2 1 1 3 3 3 1 Dynamin family AAA_16 PF13191.6 KLO11481.1 - 1.3e-05 25.6 0.1 0.18 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 KLO11481.1 - 5.3e-05 23.0 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KLO11481.1 - 7.4e-05 22.7 0.2 0.12 12.2 0.0 3.6 4 0 0 4 4 4 1 RsgA GTPase ABC_tran PF00005.27 KLO11481.1 - 0.00018 22.1 0.0 0.14 12.7 0.0 2.5 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 KLO11481.1 - 0.00019 21.4 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 KLO11481.1 - 0.0005 20.0 0.2 0.041 13.8 0.1 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KLO11481.1 - 0.00065 19.0 0.0 0.19 10.9 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Septin PF00735.18 KLO11481.1 - 0.001 18.4 0.0 0.18 11.1 0.0 2.4 2 0 0 2 2 2 1 Septin RNA_helicase PF00910.22 KLO11481.1 - 0.0011 19.3 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATP_bind_1 PF03029.17 KLO11481.1 - 0.0012 18.7 1.0 9.6 5.9 0.0 4.1 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KLO11481.1 - 0.0013 18.2 0.1 1.3 8.5 0.0 2.9 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 KLO11481.1 - 0.0017 18.0 0.1 0.33 10.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KLO11481.1 - 0.0018 18.4 0.1 0.99 9.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 KLO11481.1 - 0.0034 17.0 0.0 0.64 9.6 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KLO11481.1 - 0.0041 16.6 0.1 0.75 9.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Guanylate_kin PF00625.21 KLO11481.1 - 0.0054 16.4 0.4 0.03 14.0 0.1 2.2 2 1 1 3 3 2 1 Guanylate kinase AAA_28 PF13521.6 KLO11481.1 - 0.0061 16.8 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain SPARC_Ca_bdg PF10591.9 KLO11481.1 - 0.0062 16.8 0.5 1.4 9.2 0.0 2.9 3 0 0 3 3 2 1 Secreted protein acidic and rich in cysteine Ca binding region AAA_18 PF13238.6 KLO11481.1 - 0.0085 16.6 0.2 7.5 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.6 KLO11481.1 - 0.0098 15.7 1.6 0.45 10.4 0.0 2.7 3 0 0 3 3 2 1 EF hand G-alpha PF00503.20 KLO11481.1 - 0.013 14.7 0.0 3.2 6.8 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit AAA_14 PF13173.6 KLO11481.1 - 0.014 15.4 0.0 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KLO11481.1 - 0.014 15.8 0.0 2 8.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KLO11481.1 - 0.015 15.1 0.1 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase EF-hand_8 PF13833.6 KLO11481.1 - 0.018 14.9 0.9 1.2 9.1 0.0 3.0 3 0 0 3 3 2 0 EF-hand domain pair PduV-EutP PF10662.9 KLO11481.1 - 0.021 14.5 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 KLO11481.1 - 0.032 14.2 0.0 0.32 11.0 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NOG1 PF06858.14 KLO11481.1 - 0.032 14.0 0.1 2 8.2 0.1 2.8 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) AIG1 PF04548.16 KLO11481.1 - 0.037 13.3 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_25 PF13481.6 KLO11481.1 - 0.044 13.4 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 KLO11481.1 - 0.05 12.7 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 KLO11481.1 - 0.054 12.9 0.1 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.6 KLO11481.1 - 0.061 13.7 0.3 4.5 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KLO11481.1 - 0.069 13.1 0.0 13 5.7 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 KLO11481.1 - 0.094 12.7 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 KLO11481.1 - 0.097 12.1 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein BsuBI_PstI_RE PF06616.11 KLO11481.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain AAA_30 PF13604.6 KLO11481.1 - 0.11 12.2 0.0 4 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KLO11481.1 - 0.13 11.4 0.0 4.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) VirE PF05272.11 KLO11481.1 - 0.14 11.9 0.0 13 5.4 0.0 2.5 2 1 0 2 2 2 0 Virulence-associated protein E AAA_5 PF07728.14 KLO11481.1 - 0.19 11.8 0.1 4.9 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pkinase PF00069.25 KLO11482.1 - 8.7e-53 179.4 0.0 8.6e-24 84.3 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 KLO11482.1 - 1e-45 156.3 3.1 7.3e-45 153.5 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 KLO11482.1 - 5e-22 78.4 0.0 2e-09 37.1 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 KLO11482.1 - 2.7e-14 53.4 0.4 9.5e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 RWD domain Pkinase_fungal PF17667.1 KLO11482.1 - 0.056 12.2 0.1 0.056 12.2 0.1 2.0 2 0 0 2 2 2 0 Fungal protein kinase DIOX_N PF14226.6 KLO11483.1 - 7.9e-24 84.7 0.1 1.1e-23 84.2 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO11483.1 - 2.4e-06 28.0 0.0 9.2e-06 26.1 0.0 1.9 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily ComA PF02679.15 KLO11483.1 - 0.23 10.9 0.0 0.7 9.3 0.0 1.6 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) YTH PF04146.15 KLO11484.1 - 2.4e-59 200.0 0.0 7.7e-59 198.4 0.0 1.9 2 0 0 2 2 2 1 YT521-B-like domain CAF1 PF04857.20 KLO11488.1 - 5.3e-22 78.4 0.4 8.6e-12 44.9 0.0 2.8 1 1 1 2 2 2 2 CAF1 family ribonuclease RNase_H_2 PF13482.6 KLO11488.1 - 0.055 13.5 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 RNase_H superfamily GPI-anchored PF10342.9 KLO11489.1 - 1.7e-08 35.1 0.8 2e-08 34.9 0.8 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KLO11489.1 - 0.0052 16.6 0.0 0.0052 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Big_3_5 PF16640.5 KLO11489.1 - 0.083 13.1 3.2 0.11 12.6 3.2 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) SH3_9 PF14604.6 KLO11490.1 - 3.9e-24 84.2 0.6 3.3e-12 46.1 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KLO11490.1 - 5.3e-18 64.4 0.1 7.5e-09 35.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KLO11490.1 - 6.1e-18 64.2 0.5 3.5e-08 32.9 0.4 2.7 2 1 0 2 2 2 2 SH3 domain FCH PF00611.23 KLO11490.1 - 3.1e-16 59.4 0.1 3.1e-16 59.4 0.1 2.8 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 KLO11490.1 - 1.6e-13 50.3 2.2 3e-13 49.4 2.2 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 KLO11490.1 - 0.023 15.0 0.2 0.048 13.9 0.2 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain PHD_2 PF13831.6 KLO11490.1 - 0.19 11.3 1.9 0.42 10.2 1.9 1.5 1 0 0 1 1 1 0 PHD-finger DZR PF12773.7 KLO11490.1 - 2.2 8.4 5.4 1.1 9.3 3.1 1.7 2 0 0 2 2 2 0 Double zinc ribbon Pyridoxal_deC PF00282.19 KLO11491.1 - 4.1e-98 328.5 0.0 4.9e-98 328.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DPBB_1 PF03330.18 KLO11493.1 - 2.3e-06 27.8 0.2 0.00025 21.3 0.1 2.8 1 1 1 2 2 2 2 Lytic transglycolase Barwin PF00967.17 KLO11493.1 - 0.0021 17.9 0.2 0.0032 17.3 0.2 1.4 1 0 0 1 1 1 1 Barwin family DRMBL PF07522.14 KLO11494.1 - 0.0073 16.5 1.2 0.015 15.4 0.0 2.2 2 1 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KLO11494.1 - 0.11 12.0 2.0 5 6.6 2.0 2.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain PRP1_N PF06424.12 KLO11495.1 - 1.8e-49 167.9 14.0 1.3e-48 165.1 4.2 2.5 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KLO11495.1 - 8e-26 88.5 32.3 0.0079 16.9 0.0 14.5 8 3 8 16 16 14 9 Tetratricopeptide repeat TPR_19 PF14559.6 KLO11495.1 - 7e-21 74.5 15.9 8.7e-07 29.4 0.2 9.0 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 KLO11495.1 - 2.5e-12 47.2 16.8 0.0055 17.3 0.0 6.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KLO11495.1 - 1.5e-06 27.9 8.8 0.28 11.4 0.0 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KLO11495.1 - 1.9e-06 27.6 0.5 0.42 11.0 0.0 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KLO11495.1 - 0.00014 22.0 0.1 24 5.6 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 KLO11495.1 - 0.00081 19.9 9.6 1.2 9.9 0.0 7.4 10 0 0 10 10 9 1 Tetratricopeptide repeat Suf PF05843.14 KLO11495.1 - 0.0014 18.7 0.4 4.4 7.2 0.0 4.0 5 0 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_12 PF13424.6 KLO11495.1 - 0.0037 17.5 4.3 2.4 8.5 0.0 5.6 4 1 1 5 5 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KLO11495.1 - 0.0055 16.8 10.8 1.3 9.2 0.0 6.5 7 1 0 7 7 7 1 Tetratricopeptide repeat DUF410 PF04190.13 KLO11495.1 - 0.073 12.9 0.1 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF410) TPR_1 PF00515.28 KLO11495.1 - 0.082 12.8 3.3 3.8 7.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat FlxA PF14282.6 KLO11495.1 - 1.6 8.8 4.1 2.3 8.3 0.9 2.5 2 0 0 2 2 2 0 FlxA-like protein Mt_ATP-synt_B PF05405.14 KLO11495.1 - 2.8 7.5 6.3 4.9 6.8 1.2 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) NARP1 PF12569.8 KLO11495.1 - 8.6 5.1 11.7 12 4.7 0.0 4.2 4 1 1 5 5 4 0 NMDA receptor-regulated protein 1 Sugar_tr PF00083.24 KLO11496.1 - 3.4e-32 111.9 20.8 4.9e-32 111.4 20.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO11496.1 - 6e-28 97.8 29.8 6e-28 97.8 29.8 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1996 PF09362.10 KLO11497.1 - 1.3e-55 188.9 0.1 1.8e-55 188.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) BTB PF00651.31 KLO11498.1 - 5.9e-08 32.9 0.0 1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PIEZO PF15917.5 KLO11499.1 - 0.64 9.5 5.9 0.85 9.1 0.0 2.9 2 0 0 2 2 2 0 Piezo SNF2_N PF00176.23 KLO11500.1 - 3.5e-17 62.1 0.0 7.3e-11 41.4 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KLO11500.1 - 4.2e-13 49.3 0.0 4.2e-13 49.3 0.0 2.9 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 KLO11500.1 - 1.1e-06 29.0 0.0 2.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BRCA-2_OB3 PF09104.10 KLO11500.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Rad60-SLD PF11976.8 KLO11502.1 - 0.015 15.1 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Pkinase_Tyr PF07714.17 KLO11503.1 - 6.7e-34 117.3 0.0 9.6e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO11503.1 - 1.2e-25 90.4 0.0 1.8e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO11503.1 - 0.0019 18.1 0.0 0.35 10.7 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KLO11503.1 - 0.004 16.8 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KLO11503.1 - 0.034 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KLO11503.1 - 0.1 11.9 0.0 0.26 10.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KLO11503.1 - 0.19 10.4 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LisH PF08513.11 KLO11506.1 - 0.0001 22.1 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 LisH p450 PF00067.22 KLO11507.1 - 3.3e-74 250.3 0.0 3.7e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF859 PF05895.12 KLO11507.1 - 0.044 12.3 0.1 0.061 11.8 0.1 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) Mt_ATP-synt_B PF05405.14 KLO11508.1 - 1.1e-42 145.4 9.3 1.4e-42 145.1 9.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1931 PF09123.11 KLO11508.1 - 0.013 15.6 2.2 1.4 9.0 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) Ank_2 PF12796.7 KLO11509.1 - 4e-30 104.2 0.1 5.9e-07 30.0 0.0 7.1 6 1 1 7 7 7 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KLO11509.1 - 1.8e-20 70.9 1.3 0.036 14.6 0.0 11.0 12 0 0 12 12 12 4 Ankyrin repeat Ank_5 PF13857.6 KLO11509.1 - 9.8e-15 54.4 1.1 0.0036 17.6 0.0 7.4 7 2 2 9 9 9 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KLO11509.1 - 3.7e-14 52.9 1.2 0.016 15.8 0.0 8.9 7 2 4 11 11 11 4 Ankyrin repeats (many copies) Ank PF00023.30 KLO11509.1 - 1.9e-11 43.9 6.5 0.16 12.4 0.0 8.5 9 0 0 9 9 9 3 Ankyrin repeat CCDC-167 PF15188.6 KLO11509.1 - 0.22 11.9 4.4 0.44 10.9 0.0 3.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 ubiquitin PF00240.23 KLO11510.1 - 1.4e-06 27.9 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KLO11510.1 - 6.1e-06 26.0 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 KLO11510.1 - 0.012 16.3 0.0 0.03 15.0 0.0 1.7 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD WBS28 PF15164.6 KLO11510.1 - 0.22 10.8 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue Vezatin PF12632.7 KLO11511.1 - 0.047 13.1 1.2 1.2 8.4 0.1 2.7 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes ubiquitin PF00240.23 KLO11512.1 - 0.023 14.4 0.1 0.053 13.3 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin family SKG6 PF08693.10 KLO11513.1 - 5.2e-05 22.6 4.3 0.00013 21.3 4.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Med12-LCEWAV PF12145.8 KLO11513.1 - 0.0029 16.5 0.1 0.0043 16.0 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Rax2 PF12768.7 KLO11513.1 - 0.028 13.9 4.5 0.035 13.6 2.8 2.0 2 1 0 2 2 2 0 Cortical protein marker for cell polarity Meckelin PF09773.9 KLO11513.1 - 0.29 9.2 0.0 0.42 8.6 0.0 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) TMEM154 PF15102.6 KLO11513.1 - 0.5 10.3 10.6 16 5.4 10.6 2.4 1 1 0 1 1 1 0 TMEM154 protein family SOBP PF15279.6 KLO11513.1 - 1.7 9.2 11.5 2.3 8.7 11.4 1.2 1 1 0 1 1 1 0 Sine oculis-binding protein SOG2 PF10428.9 KLO11513.1 - 2.5 7.2 13.1 3.2 6.9 13.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1180 PF06679.12 KLO11513.1 - 3.5 8.0 13.1 0.46 10.9 6.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 KLO11514.1 - 0.0062 17.4 0.0 0.014 16.3 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KLO11514.1 - 0.025 14.5 0.2 0.059 13.3 0.2 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF5305 PF17231.2 KLO11514.1 - 0.062 12.7 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) LapA_dom PF06305.11 KLO11514.1 - 0.075 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Syndecan PF01034.20 KLO11515.1 - 0.0014 18.5 0.1 0.0025 17.7 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain RIFIN PF02009.16 KLO11515.1 - 0.22 11.4 1.3 0.34 10.8 1.3 1.2 1 0 0 1 1 1 0 Rifin SCIMP PF15050.6 KLO11515.1 - 0.3 11.5 0.6 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 SCIMP protein Apt1 PF10351.9 KLO11515.1 - 2.9 6.6 7.3 4.3 6.1 7.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain BTB PF00651.31 KLO11516.1 - 8.7e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ATP-synt_ab PF00006.25 KLO11518.1 - 1.7e-73 246.8 0.0 2.6e-73 246.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KLO11518.1 - 1.1e-43 148.5 0.1 1.9e-43 147.8 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KLO11518.1 - 1.2e-18 67.4 1.5 2.9e-18 66.1 1.5 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 KLO11518.1 - 0.072 13.3 0.4 0.23 11.6 0.2 2.0 2 1 0 2 2 2 0 HAS barrel domain Ribosomal_L21p PF00829.21 KLO11519.1 - 2.5e-24 85.5 0.2 3e-24 85.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein FF PF01846.19 KLO11520.1 - 2.7e-30 104.3 8.0 5.1e-11 42.6 0.1 6.0 5 0 0 5 5 5 5 FF domain WW PF00397.26 KLO11520.1 - 1.5e-11 44.2 16.1 1.8e-06 27.9 4.1 2.7 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KLO11520.1 - 0.056 14.1 9.3 0.087 13.5 0.3 4.3 4 1 1 5 5 5 0 p190-A and -B Rho GAPs FF domain FTCD_C PF04961.12 KLO11520.1 - 0.091 12.5 1.7 0.53 10.0 0.2 2.3 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Brix PF04427.18 KLO11521.1 - 3.1e-22 79.6 0.0 5.1e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Brix domain EcoRII-C PF09019.11 KLO11521.1 - 0.079 13.0 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 EcoRII C terminal zf-ZPR1 PF03367.13 KLO11522.1 - 1e-109 363.4 0.1 5.3e-56 188.9 0.0 2.4 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DZR PF12773.7 KLO11522.1 - 0.00081 19.4 4.0 0.031 14.3 0.1 2.9 2 1 0 2 2 2 1 Double zinc ribbon HypA PF01155.19 KLO11522.1 - 0.0023 17.9 2.1 1.3 9.0 0.3 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KLO11522.1 - 0.035 13.8 14.0 2.4 8.0 0.7 4.4 4 0 0 4 4 4 0 zinc-ribbon domain DUF2688 PF10892.8 KLO11522.1 - 0.036 13.5 3.8 6.7 6.3 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2688) FpoO PF10621.9 KLO11522.1 - 0.043 14.1 1.3 0.43 10.9 0.1 2.6 2 1 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO Zn-ribbon_8 PF09723.10 KLO11522.1 - 0.076 13.1 6.2 2.3 8.4 0.3 3.7 3 1 0 3 3 3 0 Zinc ribbon domain Polysacc_deac_2 PF04748.13 KLO11522.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase zinc-ribbons_6 PF07191.12 KLO11522.1 - 0.17 11.9 0.8 18 5.4 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbons Lar_restr_allev PF14354.6 KLO11522.1 - 0.23 11.9 1.1 47 4.5 0.0 3.7 5 0 0 5 5 5 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.11 KLO11522.1 - 0.42 10.6 4.9 31 4.6 0.1 3.5 3 1 0 3 3 3 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 KLO11522.1 - 1.1 8.8 10.5 2.2 7.8 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain MFS_1 PF07690.16 KLO11523.1 - 4.5e-29 101.5 29.2 2e-28 99.3 29.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily HMG_CoA_synt_C PF08540.10 KLO11524.1 - 1.5e-86 290.5 0.3 4.6e-86 288.9 0.3 1.7 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KLO11524.1 - 7e-85 283.3 0.2 1.1e-84 282.6 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ADH_zinc_N PF00107.26 KLO11526.1 - 3.9e-10 39.8 0.0 6.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO11526.1 - 2.8e-05 23.9 0.0 5.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KLO11526.1 - 0.036 15.1 0.0 0.26 12.4 0.0 2.1 1 1 1 2 2 2 0 Zinc-binding dehydrogenase MRC1 PF09444.10 KLO11526.1 - 0.063 13.8 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 MRC1-like domain CoA_binding_2 PF13380.6 KLO11526.1 - 0.077 13.5 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 CoA binding domain PGDYG PF14083.6 KLO11526.1 - 0.17 12.2 0.4 0.56 10.5 0.4 1.8 1 1 0 1 1 1 0 PGDYG protein Arteri_nsp7a PF16749.5 KLO11526.1 - 0.45 10.7 2.4 3.8 7.7 0.1 2.8 2 1 1 3 3 3 0 Arterivirus nonstructural protein 7 alpha DUF1752 PF08550.10 KLO11527.1 - 3.5e-10 39.5 8.9 6.7e-10 38.6 8.9 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cwf_Cwc_15 PF04889.12 KLO11528.1 - 1.1 8.9 10.9 0.27 10.9 0.9 3.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 KLO11528.1 - 3.1 8.3 8.1 1.2 9.6 0.4 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MFS_1 PF07690.16 KLO11529.1 - 4.1e-24 85.2 31.8 1.2e-23 83.6 31.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily EMP24_GP25L PF01105.24 KLO11530.1 - 9.2e-48 162.6 0.2 1e-47 162.4 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 KLO11530.1 - 0.01 16.0 0.1 0.018 15.2 0.1 1.3 1 0 0 1 1 1 0 SdrD B-like domain CarboxypepD_reg PF13620.6 KLO11530.1 - 0.067 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain VPS9 PF02204.18 KLO11531.1 - 2.2e-31 108.1 0.2 3.8e-31 107.4 0.2 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KLO11531.1 - 6.7e-16 58.4 0.4 1.9e-15 56.9 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KLO11531.1 - 1.9e-06 27.4 0.1 7.9e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 CUE domain DMA PF03474.14 KLO11531.1 - 0.0021 17.6 0.0 0.0041 16.7 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif Peptidase_C12 PF01088.21 KLO11532.1 - 5.7e-47 160.2 0.0 6.6e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ABC_membrane PF00664.23 KLO11533.1 - 9.5e-72 241.9 28.6 4e-36 125.1 12.0 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KLO11533.1 - 2.6e-54 183.5 0.0 6.2e-32 111.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KLO11533.1 - 3.9e-09 36.3 0.0 0.0026 17.2 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KLO11533.1 - 2.5e-05 24.3 1.1 0.24 11.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KLO11533.1 - 0.00018 22.0 0.1 0.22 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KLO11533.1 - 0.00067 19.6 0.4 0.42 10.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF4574 PF15141.6 KLO11533.1 - 0.00074 19.4 0.0 0.01 15.7 0.0 2.7 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 AAA_29 PF13555.6 KLO11533.1 - 0.00082 19.1 0.6 0.27 11.0 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KLO11533.1 - 0.0043 17.6 0.6 1.2 9.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KLO11533.1 - 0.0047 16.5 0.2 0.16 11.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KLO11533.1 - 0.014 15.2 3.0 3.5 7.3 0.1 3.3 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KLO11533.1 - 0.026 14.2 0.3 1.5 8.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KLO11533.1 - 0.033 13.5 0.0 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 KLO11533.1 - 0.039 14.0 2.7 3 7.9 0.8 2.5 2 0 0 2 2 2 0 Dynamin family MeaB PF03308.16 KLO11533.1 - 0.072 12.1 0.0 8.8 5.2 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KLO11533.1 - 0.078 12.2 1.3 2.2 7.4 0.5 3.1 2 1 0 2 2 2 0 NB-ARC domain ABC_ATPase PF09818.9 KLO11533.1 - 0.086 11.6 0.0 0.086 11.6 0.0 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 KLO11533.1 - 0.12 12.2 0.1 30 4.3 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein T2SSE PF00437.20 KLO11533.1 - 0.13 11.3 0.0 16 4.5 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 KLO11533.1 - 0.15 12.3 0.4 25 5.1 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KLO11533.1 - 0.22 11.6 5.0 1.5 8.9 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_22 PF13401.6 KLO11533.1 - 0.24 11.7 1.5 5.3 7.3 0.1 3.1 2 1 0 2 2 2 0 AAA domain MS_channel PF00924.18 KLO11534.1 - 3.2e-17 62.8 0.5 5.2e-17 62.1 0.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KLO11534.1 - 5.9e-06 25.5 0.4 2.3e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KLO11534.1 - 5.9e-05 22.7 0.2 0.00044 20.0 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KLO11534.1 - 0.001 19.5 0.2 0.006 17.0 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KLO11534.1 - 0.0017 17.7 0.1 0.0055 16.1 0.1 1.8 1 0 0 1 1 1 1 EF hand Glycos_transf_2 PF00535.26 KLO11535.1 - 1.4e-25 90.1 0.0 1.8e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KLO11535.1 - 1.9e-12 47.6 0.0 2.9e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KLO11535.1 - 0.0025 18.3 0.0 0.0055 17.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KLO11535.1 - 0.0026 17.3 0.0 0.0034 16.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Rcd1 PF04078.13 KLO11536.1 - 1.5e-124 414.4 5.7 1.8e-124 414.2 5.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pkinase PF00069.25 KLO11538.1 - 4.8e-35 121.2 0.0 6e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11538.1 - 8e-32 110.5 0.0 1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO11538.1 - 2.2e-05 23.9 0.0 4.4e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO11538.1 - 0.008 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KLO11538.1 - 0.012 15.5 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF935 PF06074.12 KLO11538.1 - 0.033 12.9 0.0 0.046 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Kdo PF06293.14 KLO11538.1 - 0.056 12.8 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family A_deaminase PF00962.22 KLO11539.1 - 1.8e-20 73.5 0.0 2.2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KLO11539.1 - 0.0086 15.4 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Thr_synth_N PF14821.6 KLO11540.1 - 2.9e-28 97.9 0.0 1.3e-27 95.8 0.0 2.2 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 KLO11540.1 - 8.2e-18 64.8 0.0 2.7e-17 63.1 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PRMT5_TIM PF17285.2 KLO11541.1 - 1.6e-67 227.4 0.0 3.1e-67 226.5 0.0 1.4 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KLO11541.1 - 1.6e-56 190.9 0.9 4.5e-41 140.6 0.0 2.3 1 1 1 2 2 2 2 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KLO11541.1 - 1e-55 188.4 0.0 1.5e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 KLO11541.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF4148 PF13663.6 KLO11542.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) AF-4 PF05110.13 KLO11542.1 - 1.2 7.1 14.9 1.3 7.0 14.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 KLO11542.1 - 7.2 5.0 8.8 7.8 4.9 8.8 1.0 1 0 0 1 1 1 0 Macoilin family TMEM154 PF15102.6 KLO11543.1 - 0.0037 17.2 1.6 0.0037 17.2 1.6 2.6 2 1 0 2 2 2 1 TMEM154 protein family VSP PF03302.13 KLO11543.1 - 0.0063 15.4 2.8 0.01 14.8 2.8 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Stevor PF17410.2 KLO11543.1 - 0.0089 15.6 0.1 0.014 15.0 0.1 1.1 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame AJAP1_PANP_C PF15298.6 KLO11543.1 - 0.015 15.6 4.5 0.015 15.6 4.5 2.1 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Amnionless PF14828.6 KLO11543.1 - 0.029 13.2 0.1 0.05 12.4 0.1 1.3 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 KLO11543.1 - 0.051 14.5 0.0 0.13 13.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rax2 PF12768.7 KLO11543.1 - 0.053 13.0 0.2 0.099 12.1 0.2 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity RCR PF12273.8 KLO11543.1 - 0.35 11.5 3.2 0.58 10.8 0.0 2.8 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red ECM11 PF15463.6 KLO11544.1 - 0.0037 17.8 2.2 0.0087 16.6 2.2 1.6 1 0 0 1 1 1 1 Extracellular mutant protein 11 UPF0242 PF06785.11 KLO11544.1 - 0.0054 16.9 1.6 0.0098 16.0 1.6 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Sec2p PF06428.11 KLO11544.1 - 0.022 14.7 0.5 0.049 13.6 0.5 1.6 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p HsdM_N PF12161.8 KLO11544.1 - 0.072 13.7 2.0 0.15 12.7 2.0 1.4 1 0 0 1 1 1 0 HsdM N-terminal domain DUF2597 PF10772.9 KLO11544.1 - 0.13 12.4 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) FAM76 PF16046.5 KLO11544.1 - 5.1 6.4 7.8 0.2 11.0 1.0 1.8 2 0 0 2 2 2 0 FAM76 protein Forkhead PF00250.18 KLO11546.1 - 7.2e-26 90.3 0.1 8.7e-26 90.0 0.1 1.1 1 0 0 1 1 1 1 Forkhead domain TPR_1 PF00515.28 KLO11547.1 - 5.8e-09 35.4 2.6 0.0068 16.2 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO11547.1 - 2.7e-08 33.3 3.2 0.014 15.5 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KLO11547.1 - 3e-08 34.2 0.9 9.2e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KLO11547.1 - 2.5e-07 30.3 2.6 1.1e-05 25.0 0.3 3.0 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.6 KLO11547.1 - 5e-06 26.9 1.1 3.3e-05 24.3 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KLO11547.1 - 1.4e-05 25.5 1.9 0.0068 17.1 0.7 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Serglycin PF04360.12 KLO11547.1 - 0.014 15.4 2.2 0.032 14.2 2.2 1.5 1 0 0 1 1 1 0 Serglycin TPR_7 PF13176.6 KLO11547.1 - 0.049 13.7 0.8 10 6.4 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KLO11547.1 - 0.06 13.6 0.3 20 5.7 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Phage_P2_GpE PF06528.12 KLO11547.1 - 0.14 11.7 0.4 1.1 8.8 0.1 2.6 2 0 0 2 2 2 0 Phage P2 GpE TPR_17 PF13431.6 KLO11547.1 - 0.18 12.2 3.8 9.2 6.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KLO11547.1 - 0.2 12.0 7.3 5.3 7.4 1.4 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KLO11547.1 - 0.28 11.3 2.9 22 5.2 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat LRR_4 PF12799.7 KLO11548.1 - 0.001 19.5 3.1 0.017 15.5 0.7 3.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KLO11548.1 - 0.0051 16.5 2.1 0.023 14.5 0.4 2.7 2 1 1 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 KLO11548.1 - 0.018 15.1 4.9 9.6 6.6 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Pkinase_Tyr PF07714.17 KLO11549.1 - 1.4e-31 109.7 0.0 1.8e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO11549.1 - 6.8e-28 97.8 0.0 8.9e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO11549.1 - 0.0024 17.9 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KLO11549.1 - 0.29 10.3 0.0 0.4 9.8 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase Sporozoite_P67 PF05642.11 KLO11552.1 - 1.3 7.1 16.4 1.6 6.8 16.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Arylesterase PF01731.20 KLO11553.1 - 0.00054 20.1 0.1 0.067 13.4 0.0 2.9 2 1 1 3 3 3 1 Arylesterase NHL PF01436.21 KLO11553.1 - 0.0049 16.8 0.1 12 6.2 0.0 4.4 4 0 0 4 4 4 1 NHL repeat Str_synth PF03088.16 KLO11553.1 - 0.013 15.6 0.0 0.96 9.6 0.0 2.3 2 0 0 2 2 2 0 Strictosidine synthase Na_Ca_ex PF01699.24 KLO11555.1 - 1.5e-46 158.1 50.8 4.3e-30 104.7 12.4 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein ThiF PF00899.21 KLO11557.1 - 9e-60 202.0 0.1 1.6e-59 201.2 0.0 1.3 2 0 0 2 2 2 1 ThiF family Rhodanese PF00581.20 KLO11557.1 - 7.1e-11 42.6 0.0 2.1e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 KLO11557.1 - 0.00033 20.7 0.1 0.0022 18.1 0.2 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase zf-C2H2_jaz PF12171.8 KLO11558.1 - 0.064 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding UbiA PF01040.18 KLO11559.1 - 1.6e-54 184.9 16.9 2.5e-54 184.2 16.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-Tim10_DDP PF02953.15 KLO11560.1 - 2.6e-26 91.1 1.7 3e-26 90.8 1.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cytomega_TRL10 PF06084.11 KLO11560.1 - 0.04 13.9 0.7 0.045 13.8 0.7 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DnaJ PF00226.31 KLO11561.1 - 4.4e-23 81.2 3.4 4.4e-23 81.2 3.4 2.7 3 0 0 3 3 3 1 DnaJ domain zf-met PF12874.7 KLO11561.1 - 7.5e-08 32.5 5.2 1.9e-07 31.3 0.8 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KLO11561.1 - 1.2e-07 31.8 2.5 3.9e-07 30.2 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KLO11561.1 - 2.3e-07 31.1 1.9 0.01 16.2 0.4 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KLO11561.1 - 2.7e-05 24.0 3.4 0.15 12.1 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO11561.1 - 0.0002 21.6 6.9 0.085 13.4 0.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO11561.1 - 0.00059 20.5 4.9 0.66 11.0 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger LZ3wCH PF18517.1 KLO11561.1 - 0.027 14.5 1.2 0.71 10.0 0.2 2.7 2 0 0 2 2 2 0 Leucine zipper with capping helix domain LTXXQ PF07813.12 KLO11561.1 - 0.13 13.0 0.2 0.13 13.0 0.2 3.6 4 0 0 4 4 4 0 LTXXQ motif family protein SAGA-Tad1 PF12767.7 KLO11561.1 - 2.1 8.0 9.7 4.5 6.9 0.2 2.5 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DnaJ PF00226.31 KLO11562.1 - 1.3e-23 82.9 1.6 2.9e-23 81.8 1.6 1.7 1 0 0 1 1 1 1 DnaJ domain Rft-1 PF04506.13 KLO11563.1 - 1.7e-125 419.7 22.3 2.1e-125 419.4 22.3 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 KLO11563.1 - 2e-05 24.0 10.9 0.00017 20.9 10.9 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RNase_PH PF01138.21 KLO11564.1 - 1.2e-34 119.6 0.3 4.3e-34 117.9 0.1 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KLO11564.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Homeodomain PF00046.29 KLO11565.1 - 1.7e-18 66.2 4.3 3e-18 65.4 4.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KLO11565.1 - 0.39 10.7 1.6 1.1 9.2 0.5 2.3 2 0 0 2 2 2 0 Homeobox KN domain U1snRNP70_N PF12220.8 KLO11566.1 - 3.9e-24 85.1 1.0 6.6e-24 84.4 1.0 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KLO11566.1 - 1.1e-17 63.5 0.1 1.8e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.17 KLO11567.1 - 3.9e-18 65.5 4.6 4.6e-18 65.2 4.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UPF0203 PF05254.12 KLO11567.1 - 0.08 13.2 5.9 2.5 8.4 0.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Prp18 PF02840.15 KLO11568.1 - 1.8e-61 206.4 0.1 3.3e-61 205.5 0.1 1.4 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 KLO11568.1 - 5e-10 38.8 7.3 5e-10 38.8 7.3 2.3 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Frag1 PF10277.9 KLO11569.1 - 2.3e-29 102.5 5.7 2.3e-29 102.5 5.7 3.2 2 2 0 2 2 2 1 Frag1/DRAM/Sfk1 family Adaptin_N PF01602.20 KLO11570.1 - 1.1e-119 400.4 0.0 1.6e-119 399.9 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KLO11570.1 - 3e-15 56.6 0.2 2.8e-14 53.5 0.0 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KLO11570.1 - 2.2e-09 37.6 0.9 0.00027 21.3 0.0 4.7 5 1 2 7 7 7 3 HEAT repeats HEAT PF02985.22 KLO11570.1 - 2.9e-06 27.1 3.8 0.46 10.9 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KLO11570.1 - 0.0025 18.3 0.6 0.35 11.4 0.0 4.0 4 0 0 4 4 4 1 HEAT-like repeat zf-RING_5 PF14634.6 KLO11571.1 - 0.015 15.2 0.2 0.032 14.2 0.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 KLO11571.1 - 0.019 15.2 0.3 0.041 14.2 0.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KLO11571.1 - 0.069 12.9 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 KLO11571.1 - 0.13 12.6 0.9 0.33 11.3 0.9 1.7 1 1 0 1 1 1 0 Ring finger domain GATA PF00320.27 KLO11572.1 - 6.1e-14 51.3 3.5 1.2e-13 50.4 3.5 1.5 1 0 0 1 1 1 1 GATA zinc finger Vps36-NZF-N PF16988.5 KLO11572.1 - 0.071 12.5 0.3 0.48 9.9 0.1 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_3 PF13878.6 KLO11572.1 - 0.13 12.1 0.7 12 5.8 0.0 2.7 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF1686 PF07937.11 KLO11573.1 - 0.077 12.9 4.1 0.078 12.9 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) Fungal_trans PF04082.18 KLO11574.1 - 1.7e-17 63.4 0.1 3.1e-17 62.5 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO11574.1 - 3.9e-07 30.1 15.0 6.8e-07 29.3 15.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain cobW PF02492.19 KLO11575.1 - 2e-42 144.8 0.0 2.5e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KLO11575.1 - 0.0011 19.3 0.2 0.0079 16.5 0.2 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KLO11575.1 - 0.0024 17.8 0.1 0.039 13.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase MobB PF03205.14 KLO11575.1 - 0.0034 17.3 0.0 0.0034 17.3 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 KLO11575.1 - 0.017 14.7 0.2 0.054 13.1 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF1574 PF07611.11 KLO11575.1 - 0.039 13.3 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) CobW_C PF07683.14 KLO11575.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain TsaE PF02367.17 KLO11575.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4604 PF15377.6 KLO11576.1 - 3.3e-31 109.0 22.8 3.8e-31 108.8 22.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Ferlin_C PF16165.5 KLO11576.1 - 7.4 6.5 7.4 3.3 7.6 0.5 2.2 2 0 0 2 2 2 0 Ferlin C-terminus Dyp_perox PF04261.12 KLO11577.1 - 6.1e-06 25.5 0.0 3.6e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 Dyp-type peroxidase family Abhydrolase_6 PF12697.7 KLO11578.1 - 3.1e-06 28.0 4.0 6e-06 27.0 4.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO11578.1 - 3.3e-06 26.9 0.1 0.0032 17.2 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KLO11578.1 - 2.5e-05 24.0 2.0 7e-05 22.5 0.7 1.9 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KLO11578.1 - 6e-05 22.4 0.2 0.0026 17.1 0.2 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 VirJ PF06057.11 KLO11578.1 - 0.012 15.5 0.0 0.075 12.9 0.0 2.1 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) DnaJ_C PF01556.18 KLO11579.1 - 4.7e-33 114.4 0.3 6.3e-33 114.0 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KLO11579.1 - 1.2e-24 86.2 0.4 4.3e-24 84.4 1.0 1.7 2 0 0 2 2 2 1 DnaJ domain DUF202 PF02656.15 KLO11580.1 - 6.4e-14 52.2 4.9 1.7e-13 50.8 4.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5084 PF16894.5 KLO11580.1 - 0.0022 18.4 0.6 0.0031 17.9 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5084) DUF4383 PF14325.6 KLO11580.1 - 0.017 15.4 1.0 0.03 14.6 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) MARVEL PF01284.23 KLO11582.1 - 1.6e-10 41.2 8.0 1.6e-10 41.2 8.0 1.8 1 1 0 1 1 1 1 Membrane-associating domain TMEM154 PF15102.6 KLO11582.1 - 0.038 13.9 1.2 0.086 12.7 1.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family IncE PF17627.2 KLO11582.1 - 0.56 10.2 4.5 0.32 11.0 1.9 1.9 1 1 1 2 2 2 0 Inclusion membrane protein E PIRT PF15099.6 KLO11582.1 - 10 5.7 11.1 0.055 13.0 1.5 2.0 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Mak10 PF04112.13 KLO11583.1 - 0.1 12.1 0.2 0.23 11.0 0.2 1.5 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DEAD PF00270.29 KLO11584.1 - 0.092 12.5 0.0 0.099 12.4 0.0 1.0 1 0 0 1 1 1 0 DEAD/DEAH box helicase Acetyltransf_2 PF00797.17 KLO11586.1 - 0.00073 19.4 0.0 0.0064 16.3 0.0 2.0 1 1 0 1 1 1 1 N-acetyltransferase Pkinase_Tyr PF07714.17 KLO11587.1 - 2.7e-36 125.2 0.0 4e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO11587.1 - 1.8e-32 112.7 0.0 3.1e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GrlR PF16518.5 KLO11587.1 - 0.037 14.0 0.1 0.073 13.0 0.1 1.4 1 0 0 1 1 1 0 T3SS negative regulator,GrlR APH PF01636.23 KLO11587.1 - 0.069 13.1 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KLO11587.1 - 0.094 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_M50B PF13398.6 KLO11588.1 - 7.6e-43 146.5 16.5 9.7e-43 146.1 16.5 1.1 1 0 0 1 1 1 1 Peptidase M50B-like DUF1317 PF07026.11 KLO11588.1 - 0.16 11.8 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) STE3 PF02076.15 KLO11589.1 - 2.6e-72 243.5 11.2 3.1e-72 243.2 11.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor Arteri_Gl PF00951.18 KLO11589.1 - 0.044 13.6 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein DUF2157 PF09925.9 KLO11589.1 - 0.22 11.3 0.0 0.22 11.3 0.0 2.8 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) Histone_H2A_C PF16211.5 KLO11590.1 - 3.7e-17 61.8 1.1 6.1e-17 61.1 1.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KLO11590.1 - 1.5e-16 61.0 0.0 1.9e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KLO11590.1 - 2.9e-06 27.4 0.0 3.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RhoGAP PF00620.27 KLO11591.1 - 1.1e-08 35.0 0.0 4.6e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 KLO11591.1 - 3.1e-07 30.4 0.0 5.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KLO11591.1 - 0.00019 21.7 0.0 0.00052 20.3 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain V_ATPase_I PF01496.19 KLO11591.1 - 0.35 8.7 0.3 0.63 7.9 0.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Apt1 PF10351.9 KLO11591.1 - 2.8 6.7 7.4 0.057 12.3 0.4 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain Ribonucleas_3_3 PF14622.6 KLO11592.1 - 3.7e-07 30.3 0.0 6.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KLO11592.1 - 1.6e-06 28.7 0.0 3.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KLO11592.1 - 5.1e-06 27.1 0.0 1.2e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Peptidase_M20 PF01546.28 KLO11593.1 - 2.4e-32 112.4 0.0 3.3e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KLO11593.1 - 1.5e-10 40.9 0.0 3.6e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KLO11593.1 - 0.00055 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KLO11594.1 - 3.8e-31 108.4 0.0 9.2e-31 107.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KLO11594.1 - 1.1e-13 51.0 0.0 2.1e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KLO11594.1 - 0.0012 18.5 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KLO11595.1 - 1.2e-30 106.8 0.0 2.3e-30 105.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KLO11595.1 - 3.9e-12 46.1 0.0 7.9e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KLO11595.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 DUF3455 PF11937.8 KLO11596.1 - 1.8e-26 93.4 0.0 2.3e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF3455 PF11937.8 KLO11598.1 - 7.4e-27 94.7 0.0 1e-26 94.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) hDGE_amylase PF14701.6 KLO11599.1 - 8.6e-169 562.3 0.0 1.1e-168 561.9 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KLO11599.1 - 1.9e-119 399.0 0.0 2.6e-119 398.6 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KLO11599.1 - 1.6e-81 273.7 0.0 2.3e-81 273.2 0.0 1.2 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KLO11599.1 - 4.3e-20 71.6 0.0 9.5e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme PAT1 PF09770.9 KLO11600.1 - 4.4e-95 319.7 62.4 1.2e-84 285.2 29.6 3.2 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 KLO11600.1 - 3.4 7.6 62.0 0.7 9.8 17.8 2.5 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit PLDc_2 PF13091.6 KLO11601.1 - 0.15 11.9 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 PLD-like domain Cerato-platanin PF07249.12 KLO11602.1 - 4.9e-19 68.6 0.4 5.9e-19 68.3 0.4 1.1 1 0 0 1 1 1 1 Cerato-platanin Transp_cyt_pur PF02133.15 KLO11603.1 - 9.2e-39 133.4 31.9 1.9e-38 132.4 31.9 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TFIID_30kDa PF03540.13 KLO11604.1 - 1.6e-25 88.8 0.1 2.8e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 KLO11604.1 - 0.048 13.7 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Bromodomain associated TFIIA PF03153.13 KLO11604.1 - 0.09 12.8 8.8 0.089 12.8 8.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FoP_duplication PF13865.6 KLO11604.1 - 0.11 13.0 0.3 0.11 13.0 0.3 2.3 2 1 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_60s PF00428.19 KLO11604.1 - 0.14 12.8 2.6 0.19 12.3 0.0 2.2 2 2 0 2 2 2 0 60s Acidic ribosomal protein CCDC53 PF10152.9 KLO11604.1 - 0.15 12.4 6.5 0.24 11.8 6.5 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 KLO11604.1 - 1.9 7.1 6.1 2.3 6.9 6.1 1.2 1 0 0 1 1 1 0 Presenilin XAP5 PF04921.14 KLO11604.1 - 2.2 8.1 5.3 3.2 7.5 5.3 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Fungal_trans PF04082.18 KLO11605.1 - 9.8e-20 70.7 0.2 2.4e-19 69.4 0.2 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO11605.1 - 5.9e-05 23.1 12.3 0.00013 22.0 12.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FliD_C PF07195.12 KLO11605.1 - 0.0094 15.4 0.8 0.015 14.7 0.8 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus Tropomyosin PF00261.20 KLO11605.1 - 0.021 14.2 0.7 0.032 13.6 0.7 1.2 1 0 0 1 1 1 0 Tropomyosin JIP_LZII PF16471.5 KLO11605.1 - 0.19 11.9 0.3 0.37 11.0 0.3 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II CLZ PF16526.5 KLO11605.1 - 0.19 12.1 0.2 0.46 10.9 0.2 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RNA_pol_Rpc4 PF05132.14 KLO11606.1 - 2.1e-33 115.9 0.4 2.8e-33 115.5 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 Pribosyltran PF00156.27 KLO11607.1 - 5.2e-05 22.8 0.0 9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Mito_carr PF00153.27 KLO11608.1 - 1.2e-69 230.3 4.6 2.5e-24 85.0 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein GFO_IDH_MocA PF01408.22 KLO11609.1 - 9.7e-19 68.4 0.0 1.5e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OHCU_decarbox PF09349.10 KLO11610.1 - 2.6e-32 112.5 0.0 3.3e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Med4 PF10018.9 KLO11611.1 - 4.2e-19 69.0 0.1 6e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CENP-F_leu_zip PF10473.9 KLO11611.1 - 0.031 14.3 3.6 0.044 13.8 3.6 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4472 PF14739.6 KLO11611.1 - 0.055 14.2 1.0 0.081 13.7 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) SGT1 PF07093.11 KLO11611.1 - 0.086 11.3 0.0 0.1 11.0 0.0 1.0 1 0 0 1 1 1 0 SGT1 protein SAGA-Tad1 PF12767.7 KLO11612.1 - 5.8e-24 85.1 0.0 1.5e-23 83.7 0.0 1.6 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Kinesin PF00225.23 KLO11613.1 - 1.2e-102 343.3 4.5 1.9e-102 342.6 4.5 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KLO11613.1 - 1.7e-59 200.0 0.1 5e-59 198.5 0.1 1.9 1 0 0 1 1 1 1 Microtubule binding DUF4201 PF13870.6 KLO11613.1 - 0.004 16.9 17.7 0.004 16.9 17.7 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) DUF1664 PF07889.12 KLO11613.1 - 0.013 15.5 14.4 0.12 12.4 0.7 3.3 3 1 1 4 4 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 KLO11613.1 - 0.026 14.8 11.7 0.83 10.0 0.9 3.8 1 1 2 3 3 3 0 Uncharacterized conserved protein TcpS PF17456.2 KLO11613.1 - 0.032 14.3 2.6 0.084 12.9 0.1 2.7 2 1 1 3 3 3 0 Toxin-coregulated pilus protein S CCDC74_C PF14917.6 KLO11613.1 - 0.042 14.3 4.5 0.16 12.5 4.5 2.0 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal Filament PF00038.21 KLO11613.1 - 0.05 13.2 22.5 0.025 14.1 3.1 2.5 1 1 1 2 2 2 0 Intermediate filament protein DUF4407 PF14362.6 KLO11613.1 - 0.089 12.1 15.2 0.035 13.5 12.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) KH_1 PF00013.29 KLO11613.1 - 0.12 12.2 0.1 0.37 10.6 0.1 1.8 1 0 0 1 1 1 0 KH domain YabA PF06156.13 KLO11613.1 - 0.13 12.9 21.4 1.1 9.9 2.7 5.1 4 1 1 5 5 5 0 Initiation control protein YabA SHE3 PF17078.5 KLO11613.1 - 0.14 11.9 18.6 0.35 10.5 18.6 1.7 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 MnmE_helical PF12631.7 KLO11613.1 - 0.17 12.0 12.4 0.52 10.4 0.3 3.6 2 2 0 3 3 3 0 MnmE helical domain DUF5582 PF17819.1 KLO11613.1 - 0.27 11.7 2.2 0.64 10.5 1.4 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5582) GAS PF13851.6 KLO11613.1 - 0.27 10.6 24.5 1 8.7 4.2 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KLO11613.1 - 0.29 10.0 24.8 0.13 11.1 13.6 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KLO11613.1 - 0.36 10.9 27.6 1.9 8.5 23.0 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KLO11613.1 - 0.62 10.1 29.0 0.63 10.1 17.3 3.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HTH_35 PF13693.6 KLO11613.1 - 0.66 10.1 3.4 21 5.2 0.1 3.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding MIP-T3_C PF17749.1 KLO11613.1 - 0.88 9.5 12.6 0.43 10.6 8.4 2.5 2 1 0 2 2 1 0 Microtubule-binding protein MIP-T3 C-terminal region OmpH PF03938.14 KLO11613.1 - 1.4 9.2 14.5 1.7 9.0 8.0 2.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.11 KLO11613.1 - 1.7 9.3 17.4 5.2 7.7 7.6 3.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal TFIIE_alpha PF02002.17 KLO11613.1 - 1.9 8.4 7.7 2.4 8.1 2.6 2.6 1 1 1 2 2 2 0 TFIIE alpha subunit LMBR1 PF04791.16 KLO11613.1 - 1.9 7.3 6.8 3.1 6.6 6.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein EzrA PF06160.12 KLO11613.1 - 2.7 6.0 18.8 0.49 8.5 11.6 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA HIP1_clath_bdg PF16515.5 KLO11613.1 - 4.6 7.9 25.9 1.9 9.1 11.8 3.9 2 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 KLO11613.1 - 7.2 6.7 31.3 0.32 11.1 14.0 3.3 3 1 1 4 4 2 0 Afadin- and alpha -actinin-Binding FPP PF05911.11 KLO11613.1 - 8.4 4.4 26.7 9.2 4.3 0.6 2.3 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DPBB_1 PF03330.18 KLO11614.1 - 0.00036 20.8 0.6 0.0007 19.8 0.4 1.7 1 1 0 1 1 1 1 Lytic transglycolase Aldo_ket_red PF00248.21 KLO11615.1 - 2.3e-63 214.2 0.0 2.8e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KLO11616.1 - 1.2e-60 205.2 0.0 1.4e-60 205.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RE_EcoO109I PF14511.6 KLO11616.1 - 0.12 12.0 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I DHHC PF01529.20 KLO11618.1 - 8.5e-16 58.3 9.5 1.1e-14 54.6 4.1 2.9 3 0 0 3 3 3 2 DHHC palmitoyltransferase Ribosomal_L37e PF01907.19 KLO11619.1 - 7.9e-27 93.2 12.6 1.4e-26 92.4 12.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.18 KLO11619.1 - 0.0045 17.1 1.1 0.0053 16.8 1.1 1.1 1 0 0 1 1 1 1 SelR domain HypA PF01155.19 KLO11619.1 - 0.028 14.4 0.7 0.04 13.9 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zn-ribbon_14 PF16503.5 KLO11619.1 - 0.072 12.6 3.4 0.49 10.0 0.2 2.2 2 0 0 2 2 2 0 Zinc-ribbon DUF2688 PF10892.8 KLO11619.1 - 5 6.7 7.2 15 5.2 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) DAP3 PF10236.9 KLO11620.1 - 4.2e-62 210.1 0.0 5e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KLO11620.1 - 1.9e-07 31.7 0.1 3.1e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KLO11620.1 - 0.00014 21.9 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KLO11620.1 - 0.00045 20.5 0.0 0.00083 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain PHF12_MRG_bd PF16737.5 KLO11620.1 - 0.01 15.5 0.3 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 PHD finger protein 12 MRG binding domain IstB_IS21 PF01695.17 KLO11620.1 - 0.016 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 KLO11620.1 - 0.019 14.6 0.1 0.04 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KLO11620.1 - 0.021 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KLO11620.1 - 0.13 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain OCRE PF17780.1 KLO11620.1 - 0.15 12.1 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 OCRE domain MobB PF03205.14 KLO11620.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CDC45 PF02724.14 KLO11621.1 - 0.074 11.3 0.9 0.11 10.7 0.9 1.4 1 0 0 1 1 1 0 CDC45-like protein CCDC53 PF10152.9 KLO11621.1 - 0.29 11.5 0.0 0.29 11.5 0.0 2.5 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Mito_fiss_reg PF05308.11 KLO11621.1 - 0.56 10.2 13.2 2.7 8.0 0.8 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator CPSF100_C PF13299.6 KLO11621.1 - 1.7 8.8 5.4 49 4.1 3.8 2.5 2 1 1 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Apo-VLDL-II PF05418.11 KLO11623.1 - 0.061 13.9 0.1 0.1 13.2 0.1 1.4 1 0 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) Peptidase_Mx1 PF15890.5 KLO11624.1 - 0.059 12.8 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase Suf PF05843.14 KLO11625.1 - 2.4 8.1 9.2 4.1 7.3 9.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LRR_4 PF12799.7 KLO11627.1 - 0.0023 18.3 5.0 1.4 9.4 0.1 5.0 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) YfmQ PF10787.9 KLO11627.1 - 0.034 13.9 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group F-box-like PF12937.7 KLO11628.1 - 3.1e-06 27.0 1.6 3.1e-06 27.0 1.6 2.9 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 KLO11628.1 - 0.016 15.0 2.5 0.15 12.0 0.7 2.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO11629.1 - 0.0029 17.4 1.5 0.0029 17.4 1.5 3.1 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO11630.1 - 0.00076 19.3 0.4 0.0028 17.5 0.1 2.1 2 1 0 2 2 2 1 F-box-like Glyco_hydro_cc PF11790.8 KLO11631.1 - 4.7e-65 219.5 8.6 9e-65 218.6 8.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core Gamma_PGA_hydro PF05908.11 KLO11632.1 - 0.067 12.6 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase RIO1 PF01163.22 KLO11636.1 - 2.4e-05 24.0 0.0 6.6e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KLO11636.1 - 6.6e-05 22.4 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KLO11636.1 - 0.00014 21.4 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO11636.1 - 0.0056 16.6 0.2 0.011 15.6 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.11 KLO11636.1 - 0.0079 15.8 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.17 KLO11636.1 - 0.05 12.9 0.0 0.2 10.9 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase PseudoU_synth_2 PF00849.22 KLO11638.1 - 3.4e-27 95.5 0.0 4.7e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase F-box-like PF12937.7 KLO11639.1 - 2.1e-07 30.7 0.1 8.7e-07 28.7 0.1 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO11639.1 - 0.022 14.6 0.8 8.1 6.5 0.1 3.1 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO11640.1 - 1.5e-06 28.0 0.0 6.1e-06 26.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO11641.1 - 1.5e-08 34.4 0.0 4.3e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO11641.1 - 0.0066 16.3 0.1 3.2 7.7 0.2 2.9 2 0 0 2 2 2 2 F-box domain GEN1_C PF18380.1 KLO11642.1 - 8.1e-29 100.6 0.6 1.7e-28 99.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KLO11642.1 - 9e-17 61.2 0.0 3.2e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KLO11642.1 - 2.8e-05 24.5 0.0 0.00012 22.5 0.0 2.1 1 1 0 1 1 1 1 XPG N-terminal domain Spt5_N PF11942.8 KLO11642.1 - 0.33 12.0 5.0 0.7 10.9 0.4 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal F-box PF00646.33 KLO11643.1 - 0.0001 22.0 0.5 0.0001 22.0 0.5 3.0 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KLO11643.1 - 0.0087 15.9 0.6 0.038 13.9 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KLO11643.1 - 0.014 15.3 1.4 0.056 13.3 1.4 2.2 1 1 0 1 1 1 0 F-box zf-C2H2 PF00096.26 KLO11643.1 - 2.1 9.0 4.4 6.4 7.4 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF5447 PF17525.2 KLO11644.1 - 0.067 13.7 4.5 0.15 12.6 0.1 3.5 5 0 0 5 5 5 0 Family of unknown function (DUF5447) F-box-like PF12937.7 KLO11644.1 - 0.086 12.8 1.4 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 F-box-like zf-C2H2 PF00096.26 KLO11645.1 - 0.34 11.5 2.2 0.83 10.2 0.8 2.4 2 1 0 2 2 2 0 Zinc finger, C2H2 type F-box PF00646.33 KLO11646.1 - 0.002 17.9 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO11646.1 - 0.0033 17.3 0.1 0.0045 16.9 0.1 1.2 1 0 0 1 1 1 1 F-box-like EcsB PF05975.12 KLO11646.1 - 0.054 12.3 0.1 0.058 12.2 0.1 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Shugoshin_C PF07557.11 KLO11647.1 - 0.069 13.0 0.6 0.22 11.4 0.6 1.9 1 0 0 1 1 1 0 Shugoshin C terminus SET PF00856.28 KLO11650.1 - 1.2e-07 32.3 0.0 1.9e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 SET domain P2_Phage_GpR PF06891.11 KLO11650.1 - 0.035 14.2 0.1 0.092 12.8 0.0 1.6 1 1 0 1 1 1 0 P2 phage tail completion protein R (GpR) Zn_Tnp_IS91 PF14319.6 KLO11651.1 - 5.3 7.2 9.4 1 9.5 3.8 2.4 1 1 1 2 2 2 0 Transposase zinc-binding domain Hydrolase_4 PF12146.8 KLO11652.1 - 1e-14 54.4 0.0 1e-11 44.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KLO11652.1 - 8.8e-14 51.8 0.1 7.9e-12 45.4 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO11652.1 - 7.7e-06 26.7 0.0 2.3e-05 25.1 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KLO11652.1 - 1.4e-05 25.1 0.0 0.0015 18.5 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KLO11652.1 - 0.00013 21.9 0.0 0.034 14.0 0.0 3.0 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase DLH PF01738.18 KLO11652.1 - 0.00053 19.6 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.12 KLO11652.1 - 0.00057 18.7 0.1 0.013 14.2 0.0 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KLO11652.1 - 0.0059 16.1 0.0 0.02 14.3 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.12 KLO11652.1 - 0.012 14.6 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) LIDHydrolase PF10230.9 KLO11652.1 - 0.012 15.2 0.0 0.034 13.7 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Glyco_hydro_16 PF00722.21 KLO11653.1 - 2.7e-06 27.0 0.2 5e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HNH_2 PF13391.6 KLO11654.1 - 4.2e-09 36.4 0.3 1.2e-08 34.9 0.3 1.7 1 0 0 1 1 1 1 HNH endonuclease AHH PF14412.6 KLO11654.1 - 0.18 11.8 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Sugar_tr PF00083.24 KLO11655.1 - 1.3e-77 261.6 17.9 1.6e-77 261.3 17.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO11655.1 - 1.6e-31 109.6 15.6 1.6e-31 109.6 15.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KLO11655.1 - 0.0014 17.1 0.7 0.0021 16.6 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KLO11655.1 - 0.0079 14.6 5.4 0.016 13.6 0.3 2.3 1 1 1 2 2 2 2 Transmembrane secretion effector CTP_transf_like PF01467.26 KLO11656.1 - 4.1e-06 27.0 0.0 5.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF21 PF01595.20 KLO11657.1 - 0.38 10.4 8.4 0.68 9.6 8.4 1.4 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain B12D PF06522.11 KLO11657.1 - 5.6 6.8 5.1 1.7 8.5 0.9 2.2 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit CDH-cyt PF16010.5 KLO11658.1 - 4.9e-54 182.8 3.4 1.3e-53 181.4 2.0 2.2 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KLO11658.1 - 1.1e-18 67.7 0.0 3.1e-18 66.2 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO11658.1 - 2.4e-18 67.1 0.1 4.8e-18 66.1 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KLO11658.1 - 1.6e-06 28.3 0.1 4.2e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO11658.1 - 2.7e-05 23.9 0.0 0.00072 19.2 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO11658.1 - 5.5e-05 22.4 0.2 0.00011 21.4 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO11658.1 - 6.3e-05 22.4 0.1 0.00011 21.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KLO11658.1 - 0.00018 20.9 0.4 0.0003 20.2 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KLO11658.1 - 0.00021 20.1 0.0 0.00034 19.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KLO11658.1 - 0.00022 20.6 0.1 0.02 14.1 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KLO11658.1 - 0.0015 18.0 0.3 0.005 16.2 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KLO11658.1 - 0.0022 17.3 0.0 0.026 13.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KLO11658.1 - 0.061 12.4 0.1 0.089 11.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KLO11658.1 - 0.24 10.4 0.1 0.38 9.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A F-box-like PF12937.7 KLO11659.1 - 1.2e-06 28.2 0.5 4.4e-06 26.5 0.5 2.0 1 1 0 1 1 1 1 F-box-like O-FucT PF10250.9 KLO11659.1 - 0.092 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase WSC PF01822.19 KLO11660.1 - 1.6e-59 198.0 55.2 1.8e-16 60.1 8.7 4.4 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 KLO11660.1 - 2e-28 99.2 0.0 1.9e-27 96.0 0.0 2.4 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KLO11660.1 - 6e-20 71.3 0.1 1.3e-19 70.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KLO11660.1 - 0.039 14.3 0.0 0.45 10.9 0.0 3.0 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.15 KLO11660.1 - 0.11 12.5 2.5 0.89 9.6 0.1 3.7 4 0 0 4 4 4 0 Kelch motif F-box-like PF12937.7 KLO11661.1 - 6.9e-08 32.3 0.1 3.3e-07 30.1 0.1 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO11661.1 - 0.017 15.0 0.7 5.2 7.1 0.1 2.9 2 0 0 2 2 2 0 F-box domain PseudoU_synth_2 PF00849.22 KLO11662.1 - 2.9e-26 92.5 0.0 4.4e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase F-box-like PF12937.7 KLO11663.1 - 4.5e-08 32.9 0.0 4.5e-08 32.9 0.0 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO11663.1 - 0.11 12.5 3.5 0.67 9.9 0.9 3.1 2 1 0 2 2 2 0 F-box domain Rap_GAP PF02145.15 KLO11664.1 - 4.3e-41 140.5 0.0 7.6e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KLO11664.1 - 5.5e-39 134.3 1.5 3.7e-37 128.2 0.0 2.7 3 0 0 3 3 3 2 Tuberin DUF3384 PF11864.8 KLO11664.1 - 3.3e-07 29.6 0.1 1e-05 24.7 0.1 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3384) YccF PF03733.13 KLO11664.1 - 0.16 12.7 0.3 0.49 11.1 0.3 1.8 1 0 0 1 1 1 0 Inner membrane component domain 4HBT PF03061.22 KLO11665.1 - 8.6e-07 29.2 0.2 0.0074 16.6 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily zf-MYND PF01753.18 KLO11666.1 - 2.7e-09 37.0 14.7 4.8e-09 36.2 14.7 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KLO11666.1 - 0.24 11.7 7.8 0.74 10.2 7.8 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KLO11667.1 - 0.028 14.5 4.7 0.059 13.5 4.7 1.5 1 0 0 1 1 1 0 MYND finger zf-MYND PF01753.18 KLO11668.1 - 4.2e-09 36.3 10.3 1.2e-08 34.8 10.3 1.9 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO11668.1 - 0.12 12.5 6.9 0.091 12.9 4.8 1.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KLO11668.1 - 2.7 8.3 10.0 0.74 10.2 6.1 2.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KLO11669.1 - 1.9e-10 40.7 11.9 1.9e-10 40.7 11.9 2.4 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.7 KLO11669.1 - 0.086 14.0 2.6 0.17 13.0 2.6 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Amino_oxidase PF01593.24 KLO11670.1 - 1.1e-66 226.0 0.0 1.4e-66 225.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KLO11670.1 - 6.9e-09 35.8 0.1 1.6e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO11670.1 - 1.2e-06 28.0 0.0 0.0065 15.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO11670.1 - 0.00084 19.9 1.2 0.053 14.1 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO11670.1 - 0.0017 18.0 0.3 0.008 15.8 0.6 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KLO11670.1 - 0.0017 17.8 0.7 0.004 16.6 0.7 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KLO11670.1 - 0.0059 15.9 0.7 0.0098 15.2 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KLO11670.1 - 0.012 14.7 0.3 0.017 14.2 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KLO11670.1 - 0.039 13.9 0.8 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KLO11670.1 - 0.041 12.6 0.4 0.69 8.5 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KLO11670.1 - 0.048 12.9 0.3 0.083 12.2 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KLO11670.1 - 0.082 12.1 0.8 5.8 6.1 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAA_11 PF13086.6 KLO11671.1 - 8.9e-16 58.5 0.0 7e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KLO11671.1 - 2.3e-10 40.5 0.0 1.7e-09 37.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO11671.1 - 1.5e-07 31.9 0.0 6.4e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KLO11671.1 - 1.5e-05 24.7 0.0 2.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO11671.1 - 0.00014 22.3 0.0 0.00037 20.9 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KLO11671.1 - 0.0022 18.4 0.0 0.0079 16.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO11671.1 - 0.0034 17.7 0.0 0.021 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KLO11671.1 - 0.02 14.7 0.1 0.92 9.2 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KLO11671.1 - 0.025 13.8 0.0 0.099 11.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KLO11671.1 - 0.054 13.0 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 KLO11671.1 - 0.062 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Helicase_RecD PF05127.14 KLO11671.1 - 0.068 13.0 0.0 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 Helicase AAA_7 PF12775.7 KLO11671.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KLO11671.1 - 0.097 13.2 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KLO11671.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase RNA12 PF10443.9 KLO11671.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein AAA_12 PF13087.6 KLO11672.1 - 6.2e-20 71.7 0.0 6.9e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KLO11672.1 - 0.00029 20.6 0.0 0.0018 18.1 0.0 2.1 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain Asp PF00026.23 KLO11674.1 - 1.4e-78 264.5 4.9 1.9e-78 264.1 4.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO11674.1 - 2.4e-07 31.2 2.9 0.0014 18.9 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KLO11674.1 - 0.0021 17.8 0.3 0.0051 16.6 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal BTB_3 PF16017.5 KLO11675.1 - 0.053 13.6 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain Dynactin_p22 PF07426.11 KLO11676.1 - 0.0071 16.2 1.6 0.014 15.3 0.8 1.6 1 1 1 2 2 2 1 Dynactin subunit p22 DUF2164 PF09932.9 KLO11676.1 - 0.034 14.2 1.1 0.074 13.1 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2164) Baculo_PEP_C PF04513.12 KLO11676.1 - 0.14 12.2 2.8 0.44 10.6 2.8 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HIP1_clath_bdg PF16515.5 KLO11676.1 - 0.24 12.0 2.6 0.62 10.7 0.1 2.4 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ArdA PF07275.11 KLO11677.1 - 0.028 15.0 0.4 0.056 14.0 0.0 1.6 2 0 0 2 2 2 0 Antirestriction protein (ArdA) TssN PF17555.2 KLO11679.1 - 0.35 10.2 8.8 0.66 9.3 8.8 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN EphA2_TM PF14575.6 KLO11683.1 - 0.78 10.7 2.2 1.8 9.5 0.0 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Vault PF01505.18 KLO11685.1 - 0.091 12.9 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 Major Vault Protein repeat domain Herpes_BTRF1 PF04682.12 KLO11687.1 - 0.094 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region DUF863 PF05904.11 KLO11689.1 - 0.012 14.1 0.4 0.018 13.5 0.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) KinB_sensor PF16767.5 KLO11689.1 - 0.072 13.6 0.1 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Pkinase PF00069.25 KLO11690.1 - 6.2e-26 91.3 0.0 7.5e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11690.1 - 3.1e-21 75.8 0.0 3.9e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO11690.1 - 0.0019 17.6 0.1 0.0079 15.5 0.1 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KLO11690.1 - 0.0055 16.7 0.0 0.0067 16.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO11690.1 - 0.0066 16.1 0.0 0.0089 15.6 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KLO11690.1 - 0.009 14.8 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO11692.1 - 6.7e-40 137.1 0.0 9.5e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11692.1 - 1.5e-35 122.7 0.0 2.1e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO11692.1 - 0.00098 18.5 0.0 0.0024 17.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO11692.1 - 0.0058 16.2 0.1 0.019 14.6 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KLO11692.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EphA2_TM PF14575.6 KLO11693.1 - 0.46 11.4 0.0 0.46 11.4 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RNase_H PF00075.24 KLO11694.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 RNase H zf-FPG_IleRS PF06827.14 KLO11694.1 - 0.12 12.3 0.8 0.28 11.1 0.8 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS IL32 PF15225.6 KLO11694.1 - 0.13 12.6 1.8 7.1 7.1 0.2 2.4 2 0 0 2 2 2 0 Interleukin 32 DUF664 PF04978.12 KLO11695.1 - 0.033 14.6 0.4 2.6 8.4 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF664) Pkinase PF00069.25 KLO11696.1 - 2.1e-34 119.1 0.0 2.2e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11696.1 - 1.9e-30 106.1 0.0 2.2e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO11696.1 - 4.9e-05 22.3 0.0 5.4e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO11696.1 - 0.00038 19.8 0.1 0.001 18.4 0.1 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO11696.1 - 0.0067 16.0 0.0 0.0099 15.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KLO11696.1 - 0.0082 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO11696.1 - 0.093 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KLO11698.1 - 1.7e-40 139.1 0.0 2.5e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11698.1 - 3.6e-35 121.5 0.0 5.5e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO11698.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO11698.1 - 0.00042 20.0 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KLO11698.1 - 0.00045 19.1 0.0 0.00076 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO11698.1 - 0.0034 16.8 0.0 0.0072 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO11698.1 - 0.09 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SRP40_C PF05022.12 KLO11700.1 - 0.58 11.1 9.0 0.22 12.4 6.0 1.8 2 0 0 2 2 2 0 SRP40, C-terminal domain CheZ PF04344.13 KLO11701.1 - 0.0063 16.4 0.8 0.0093 15.9 0.8 1.2 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ Nsp1_C PF05064.13 KLO11701.1 - 0.098 12.5 1.5 0.16 11.8 1.3 1.4 1 1 0 1 1 1 0 Nsp1-like C-terminal region TPR_MLP1_2 PF07926.12 KLO11701.1 - 0.75 9.9 5.4 3.1 7.9 5.5 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 KLO11702.1 - 0.0051 16.3 8.9 0.0051 16.3 8.9 2.0 2 0 0 2 2 2 1 Golgin subfamily A member 5 COG2 PF06148.11 KLO11702.1 - 0.012 15.7 4.8 0.012 15.7 4.8 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tho2 PF11262.8 KLO11702.1 - 0.025 13.8 2.1 0.05 12.8 2.1 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 NPV_P10 PF05531.12 KLO11702.1 - 0.026 15.0 1.3 0.026 15.0 1.3 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KLO11702.1 - 0.05 13.6 1.4 0.05 13.6 1.4 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KLO11702.1 - 0.12 12.7 4.6 0.27 11.5 2.5 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 KLO11702.1 - 0.17 11.9 13.0 0.89 9.6 5.0 2.3 2 0 0 2 2 2 0 Laminin Domain II IFT57 PF10498.9 KLO11702.1 - 0.18 10.8 11.1 0.056 12.4 4.8 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MCPsignal PF00015.21 KLO11702.1 - 0.2 11.5 6.6 0.13 12.0 2.5 2.4 2 2 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_PEP_C PF04513.12 KLO11702.1 - 0.27 11.3 3.5 0.22 11.6 2.2 1.6 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GHMP_kinases_C PF08544.13 KLO11702.1 - 0.54 10.7 2.3 32 5.0 0.9 3.0 2 1 0 2 2 2 0 GHMP kinases C terminal Spc7 PF08317.11 KLO11702.1 - 0.63 8.9 17.6 0.093 11.6 7.9 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Spectrin PF00435.21 KLO11702.1 - 0.66 10.5 12.7 2.7 8.5 6.9 2.7 2 1 1 3 3 3 0 Spectrin repeat T3SSipB PF16535.5 KLO11702.1 - 0.67 10.4 9.4 0.22 12.0 2.8 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF148 PF02520.17 KLO11702.1 - 0.81 9.8 8.2 0.48 10.5 2.6 2.5 2 1 1 3 3 2 0 Domain of unknown function DUF148 TPR_MLP1_2 PF07926.12 KLO11702.1 - 0.87 9.7 19.3 0.031 14.3 8.8 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Lectin_N PF03954.14 KLO11702.1 - 0.92 9.3 5.9 0.24 11.1 2.3 1.9 3 0 0 3 3 2 0 Hepatic lectin, N-terminal domain GAS PF13851.6 KLO11702.1 - 1.5 8.1 19.2 0.047 13.0 9.7 2.8 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding KxDL PF10241.9 KLO11702.1 - 2 8.8 9.0 2.5 8.4 6.7 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein Syntaxin_2 PF14523.6 KLO11702.1 - 2.3 8.6 8.4 0.77 10.2 3.7 2.2 2 1 0 2 2 2 0 Syntaxin-like protein HisKA_3 PF07730.13 KLO11702.1 - 2.5 8.7 14.0 0.98 10.0 1.4 3.4 2 2 1 3 3 3 0 Histidine kinase GST_C PF00043.25 KLO11702.1 - 2.7 8.3 5.0 16 5.8 1.3 2.7 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3450 PF11932.8 KLO11702.1 - 2.8 7.2 15.0 1.4 8.1 8.5 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF3450) KELK PF15796.5 KLO11702.1 - 4.1 7.9 17.1 2 8.9 8.8 3.2 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase OmpH PF03938.14 KLO11702.1 - 4.3 7.7 15.9 1.6 9.0 5.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF16 PF01519.16 KLO11702.1 - 4.9 7.7 10.6 3 8.4 4.6 3.1 1 1 0 2 2 2 0 Protein of unknown function DUF16 TMPIT PF07851.13 KLO11702.1 - 5 6.3 10.5 0.55 9.4 4.6 1.9 2 0 0 2 2 2 0 TMPIT-like protein XhlA PF10779.9 KLO11702.1 - 5.1 7.4 7.3 2.5 8.4 2.5 2.6 1 1 1 2 2 2 0 Haemolysin XhlA UPF0242 PF06785.11 KLO11702.1 - 5.1 7.2 18.3 1.9e+02 2.0 18.3 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 KLO11702.1 - 7.7 6.9 17.7 1.1 9.6 6.9 2.2 2 0 0 2 2 2 0 Fez1 Jnk-SapK_ap_N PF09744.9 KLO11703.1 - 0.027 14.7 11.2 0.022 15.0 3.4 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF327 PF03885.13 KLO11704.1 - 0.0046 16.9 0.3 0.0046 16.9 0.3 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF327) Zip PF02535.22 KLO11704.1 - 1.8 7.7 3.3 2 7.5 3.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ccdc124 PF06244.12 KLO11705.1 - 3.1e-29 102.1 2.5 6e-29 101.2 0.2 2.0 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF2852 PF11014.8 KLO11705.1 - 0.29 11.3 5.6 4.1 7.6 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Fasciclin PF02469.22 KLO11710.1 - 1.4e-08 35.0 0.0 2.4e-08 34.2 0.0 1.3 1 1 0 1 1 1 1 Fasciclin domain Adaptin_N PF01602.20 KLO11711.1 - 1.4e-92 310.9 3.4 2.2e-92 310.3 3.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KLO11711.1 - 3e-61 205.0 0.0 8.9e-61 203.5 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KLO11711.1 - 3.2e-53 179.4 0.7 6.6e-53 178.4 0.0 1.9 2 0 0 2 2 2 1 Coatomer beta C-terminal region Cnd1 PF12717.7 KLO11711.1 - 5.1e-10 39.6 2.7 0.0005 20.1 0.0 3.8 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KLO11711.1 - 7.8e-06 26.2 1.3 0.18 12.2 0.0 4.4 3 1 1 5 5 4 2 HEAT repeats HEAT PF02985.22 KLO11711.1 - 2.2e-05 24.3 0.0 0.18 12.1 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 KLO11711.1 - 6.4e-05 23.1 0.0 0.00028 21.0 0.0 2.2 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_EZ PF13513.6 KLO11711.1 - 0.00059 20.3 0.1 4.1 8.0 0.1 4.2 4 1 1 5 5 5 2 HEAT-like repeat DUF5578 PF17741.1 KLO11711.1 - 0.0022 17.5 2.1 0.26 10.6 0.2 3.0 2 1 1 3 3 3 2 Family of unknown function (DUF5578) RTP1_C1 PF10363.9 KLO11711.1 - 0.065 13.4 1.7 1.8 8.8 0.1 2.9 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 KLO11711.1 - 0.18 11.9 2.1 5.1 7.2 0.0 2.9 3 0 0 3 3 3 0 Parkin co-regulated protein Pkinase PF00069.25 KLO11712.1 - 1.1e-31 110.2 0.0 1.3e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11712.1 - 1.5e-29 103.1 0.1 1.8e-29 102.9 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO11712.1 - 9.2e-05 21.4 0.0 0.00011 21.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO11712.1 - 0.0043 16.4 0.1 0.009 15.4 0.0 1.6 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 KLO11712.1 - 0.0077 15.8 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KLO11712.1 - 0.024 14.0 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO11712.1 - 0.068 13.1 0.0 0.21 11.5 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KLO11712.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_hydro_7 PF00840.20 KLO11714.1 - 7.5e-205 680.7 15.7 7.5e-205 680.7 15.7 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KLO11714.1 - 2.8e-12 46.3 11.7 2.8e-12 46.3 11.7 4.7 5 1 0 5 5 5 1 Fungal cellulose binding domain DUF2367 PF10164.9 KLO11715.1 - 2.7e-06 27.8 7.6 8.5e-06 26.2 7.6 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) CUE PF02845.16 KLO11716.1 - 1.3e-07 31.1 0.0 2.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain YtxH PF12732.7 KLO11716.1 - 0.034 14.7 0.4 0.06 13.9 0.4 1.3 1 0 0 1 1 1 0 YtxH-like protein CoA_transf_3 PF02515.17 KLO11716.1 - 0.14 11.2 0.3 0.25 10.4 0.3 1.3 1 0 0 1 1 1 0 CoA-transferase family III peroxidase PF00141.23 KLO11717.1 - 6.4e-28 98.0 0.0 1e-27 97.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KLO11717.1 - 2.2e-25 88.4 1.1 6.4e-25 86.9 0.5 2.0 2 0 0 2 2 2 1 Fungal peroxidase extension region RIBIOP_C PF04950.12 KLO11718.1 - 7.4e-106 353.8 0.0 1.4e-105 352.9 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KLO11718.1 - 2.1e-19 69.4 0.0 8e-19 67.5 0.0 2.1 2 0 0 2 2 2 1 AARP2CN (NUC121) domain DUF3844 PF12955.7 KLO11719.1 - 3.8e-31 107.3 2.7 5.7e-31 106.8 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) peroxidase PF00141.23 KLO11720.1 - 6.3e-31 107.8 0.0 1e-30 107.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KLO11720.1 - 2.1e-27 94.8 3.7 3e-27 94.4 2.4 1.9 2 0 0 2 2 2 1 Fungal peroxidase extension region DUF1674 PF07896.12 KLO11721.1 - 5.9e-18 65.1 3.4 5.9e-18 65.1 3.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) Fungal_trans PF04082.18 KLO11722.1 - 4.2e-20 71.9 0.0 1.4e-19 70.2 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO11722.1 - 2.4e-08 34.0 12.3 4.6e-08 33.0 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KLO11722.1 - 3.8e-05 23.8 0.0 0.00011 22.3 0.0 1.7 2 0 0 2 2 2 1 Gal4-like dimerisation domain Multi-haem_cyto PF13447.6 KLO11722.1 - 0.056 12.7 1.7 0.12 11.6 1.7 1.4 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH ASC PF00858.24 KLO11722.1 - 0.12 11.4 0.9 0.22 10.5 0.1 1.8 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel G-alpha PF00503.20 KLO11724.1 - 1.3e-117 392.9 0.1 1.6e-117 392.7 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO11724.1 - 4.6e-16 58.8 0.5 6e-11 42.1 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KLO11724.1 - 0.00023 20.6 1.5 0.0097 15.3 0.0 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KLO11724.1 - 0.0078 16.4 1.0 4.1 7.6 0.0 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KLO11724.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KLO11724.1 - 0.1 12.7 0.0 5 7.3 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KLO11724.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family zf-CHC2 PF01807.20 KLO11724.1 - 0.13 12.1 0.0 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger AAA_24 PF13479.6 KLO11724.1 - 0.15 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain tRNA-synt_2c PF01411.19 KLO11725.1 - 1.5e-218 726.8 0.0 2.3e-218 726.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KLO11725.1 - 2.6e-16 59.4 0.4 5.9e-16 58.3 0.4 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KLO11725.1 - 1.4e-09 38.5 4.7 4.9e-09 36.7 4.7 2.0 1 1 0 1 1 1 1 DHHA1 domain Globin PF00042.22 KLO11725.1 - 0.12 13.0 0.1 0.45 11.1 0.1 2.0 1 0 0 1 1 1 0 Globin G-alpha PF00503.20 KLO11726.1 - 2.4e-109 365.7 0.0 3.6e-109 365.2 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO11726.1 - 3.3e-09 36.5 0.0 1e-07 31.6 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KLO11726.1 - 0.034 14.4 0.0 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KLO11726.1 - 0.13 11.9 0.0 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Ras family EI24 PF07264.11 KLO11727.1 - 6.3e-11 42.8 2.8 8.9e-11 42.4 2.8 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LMBR1 PF04791.16 KLO11727.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Prenylcys_lyase PF07156.14 KLO11728.1 - 1.2e-66 225.3 0.0 1.6e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KLO11728.1 - 1.8e-10 40.9 0.0 4.1e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KLO11728.1 - 3.8e-10 39.7 0.0 5.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KLO11728.1 - 1.4e-05 24.8 0.0 7.3e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO11728.1 - 0.0059 15.9 0.0 0.054 12.7 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO11728.1 - 0.011 15.0 0.2 0.022 14.0 0.2 1.4 1 0 0 1 1 1 0 Thi4 family DUF1207 PF06727.11 KLO11728.1 - 0.031 13.2 0.1 0.047 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) NAD_binding_9 PF13454.6 KLO11728.1 - 0.035 14.1 0.1 0.62 10.0 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KLO11728.1 - 0.047 13.0 0.1 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KLO11728.1 - 0.051 12.8 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KLO11728.1 - 0.095 11.8 0.4 0.18 10.8 0.4 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-CCHC PF00098.23 KLO11729.1 - 1.4e-11 43.9 24.0 0.00038 20.4 1.3 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 KLO11729.1 - 5.8e-06 26.0 14.2 0.073 12.9 0.1 4.3 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 KLO11729.1 - 0.0043 16.8 17.3 0.78 9.5 0.2 4.2 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_5 PF14787.6 KLO11729.1 - 0.15 11.8 19.5 0.94 9.2 1.1 4.1 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger PHD_4 PF16866.5 KLO11729.1 - 0.32 11.1 9.9 0.71 10.0 1.9 3.2 2 1 1 3 3 3 0 PHD-finger zf-CCHC_3 PF13917.6 KLO11729.1 - 1.7 8.6 19.7 3 7.9 0.4 4.3 3 1 1 4 4 4 0 Zinc knuckle Lipase_3 PF01764.25 KLO11732.1 - 1.8e-17 63.5 0.0 2.3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Methyltransf_25 PF13649.6 KLO11733.1 - 4.9e-12 46.4 0.0 1.4e-11 44.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO11733.1 - 1e-11 45.3 0.0 1.8e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO11733.1 - 4.1e-09 36.4 0.0 2.3e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO11733.1 - 2.4e-07 30.3 0.0 6.7e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KLO11733.1 - 6.3e-07 29.4 0.0 9.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO11733.1 - 6e-06 26.9 0.0 1.6e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KLO11733.1 - 0.0011 19.1 0.0 0.0014 18.8 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 KLO11733.1 - 0.003 17.5 0.0 0.0065 16.3 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase TPMT PF05724.11 KLO11733.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 KLO11733.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain bZIP_2 PF07716.15 KLO11736.1 - 1.3e-09 37.9 13.7 2.6e-09 37.0 13.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KLO11736.1 - 0.0018 18.3 11.9 0.0049 16.9 11.9 1.7 1 1 0 1 1 1 1 bZIP transcription factor TPR_MLP1_2 PF07926.12 KLO11736.1 - 0.019 15.0 0.9 0.019 15.0 0.9 1.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Shugoshin_N PF07558.11 KLO11736.1 - 0.082 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 KLO11736.1 - 0.13 12.6 0.5 0.29 11.4 0.5 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Sulf_transp PF04143.14 KLO11738.1 - 0.0093 15.6 0.0 0.01 15.4 0.0 1.0 1 0 0 1 1 1 1 Sulphur transport HCV_NS4a PF01006.20 KLO11738.1 - 0.072 12.9 0.3 0.14 11.9 0.3 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a RSN1_TM PF13967.6 KLO11738.1 - 0.087 12.6 0.0 0.087 12.6 0.0 1.6 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport ATP1G1_PLM_MAT8 PF02038.16 KLO11738.1 - 3.6 7.1 4.6 0.48 9.9 0.2 1.8 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Gti1_Pac2 PF09729.9 KLO11741.1 - 3e-22 79.6 1.6 2.1e-21 76.8 1.2 2.3 1 1 0 1 1 1 1 Gti1/Pac2 family DUF2724 PF10893.8 KLO11741.1 - 0.043 13.7 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) GLTP PF08718.11 KLO11744.1 - 1.7e-42 145.2 0.0 2.2e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) GAF_2 PF13185.6 KLO11745.1 - 0.00057 20.2 0.0 0.001 19.4 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KLO11745.1 - 0.0067 17.0 0.0 0.0096 16.6 0.0 1.4 1 0 0 1 1 1 1 GAF domain Gti1_Pac2 PF09729.9 KLO11747.1 - 2.4e-30 106.0 1.7 2.2e-26 93.0 0.2 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 KLO11748.1 - 8.5e-23 81.4 0.0 2.1e-20 73.5 0.0 2.5 1 1 1 2 2 2 2 Gti1/Pac2 family TFIIA PF03153.13 KLO11750.1 - 2.2e-54 186.1 12.8 1e-32 114.7 7.7 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 KLO11750.1 - 6 5.9 13.1 8.4 5.5 13.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PALP PF00291.25 KLO11751.1 - 2.3e-50 171.7 0.0 1.4e-26 93.6 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Myb_DNA-binding PF00249.31 KLO11752.1 - 2.5e-11 43.6 0.1 6.2e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KLO11752.1 - 1.9e-09 37.7 0.0 4.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KLO11752.1 - 0.0016 18.7 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain p450 PF00067.22 KLO11753.1 - 2e-66 224.7 0.0 2.6e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 zf-CCCH PF00642.24 KLO11754.1 - 2.1e-09 37.0 2.7 4.8e-09 35.9 2.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KLO11754.1 - 5.6e-08 32.5 5.0 1.1e-07 31.6 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO11754.1 - 1.4e-06 28.1 7.9 2.4e-06 27.4 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KLO11754.1 - 1.6e-06 28.0 6.2 3.2e-06 27.1 6.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 KLO11754.1 - 1.3e-05 25.0 4.4 3e-05 23.9 4.4 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4 PF00097.25 KLO11754.1 - 4e-05 23.4 8.6 7.3e-05 22.6 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO11754.1 - 6.4e-05 22.7 7.9 0.00012 21.8 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KLO11754.1 - 0.00048 20.2 3.6 0.00048 20.2 3.6 1.5 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KLO11754.1 - 0.00054 20.2 6.3 0.001 19.4 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KLO11754.1 - 0.00099 19.2 7.3 0.0023 18.0 7.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_4 PF18044.1 KLO11754.1 - 0.0014 18.4 2.9 0.003 17.3 2.9 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-Nse PF11789.8 KLO11754.1 - 0.14 12.0 1.9 0.24 11.2 1.9 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KLO11754.1 - 0.22 11.4 6.1 0.4 10.6 6.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 C1_2 PF03107.16 KLO11754.1 - 1.3 9.4 5.8 2.2 8.7 2.3 2.4 1 1 1 2 2 2 0 C1 domain zf-RanBP PF00641.18 KLO11754.1 - 8.1 5.9 6.9 0.24 10.7 0.7 1.7 2 0 0 2 2 1 0 Zn-finger in Ran binding protein and others APP_N PF02177.16 KLO11755.1 - 0.13 12.7 0.4 0.21 12.0 0.4 1.3 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding Ribosomal_S8e PF01201.22 KLO11757.1 - 2.3e-48 163.9 2.7 2.3e-48 163.9 2.7 1.8 1 1 1 2 2 2 1 Ribosomal protein S8e Yip1 PF04893.17 KLO11758.1 - 1.3e-11 44.5 12.0 1.5e-11 44.3 11.2 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1168 PF06658.12 KLO11759.1 - 4.5e-39 133.4 14.6 6.4e-39 132.9 14.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) ARHGEF5_35 PF15441.6 KLO11759.1 - 0.044 12.8 11.6 0.057 12.4 11.6 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 Lyase_catalyt PF09093.11 KLO11759.1 - 0.045 12.9 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Lyase, catalytic Peptidase_S49_N PF08496.10 KLO11759.1 - 2.7 8.0 8.3 4.1 7.4 8.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PPL5 PF18168.1 KLO11759.1 - 5 6.3 7.4 6.7 5.9 7.4 1.1 1 0 0 1 1 1 0 Prim-pol family 5 SAPS PF04499.15 KLO11759.1 - 8.2 5.1 7.3 10 4.8 7.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF647 PF04884.14 KLO11760.1 - 2.5e-82 276.1 6.7 8e-82 274.5 6.7 1.7 1 1 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Cwf_Cwc_15 PF04889.12 KLO11760.1 - 1.8 8.2 9.4 2.6 7.7 9.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4813 PF16072.5 KLO11762.1 - 1.4 8.5 13.8 1.9 8.1 13.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4813) MULE PF10551.9 KLO11763.1 - 7.2e-09 35.9 0.0 5.1e-08 33.2 0.0 2.4 1 1 0 1 1 1 1 MULE transposase domain YvbH_ext PF11724.8 KLO11763.1 - 2.6 8.4 4.9 26 5.3 0.2 3.1 3 0 0 3 3 3 0 YvbH-like oligomerisation region PPTA PF01239.22 KLO11765.1 - 0.032 14.0 0.2 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Tet_JBP PF12851.7 KLO11765.1 - 0.084 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Pheromone PF08015.11 KLO11766.1 - 7.2 7.7 15.6 3.7 8.7 2.6 3.0 3 0 0 3 3 3 0 Fungal mating-type pheromone AAA_16 PF13191.6 KLO11767.1 - 8.3e-07 29.5 0.1 3.2e-06 27.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KLO11767.1 - 0.00046 20.1 0.0 0.0022 17.9 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KLO11767.1 - 0.0062 16.8 0.0 0.025 14.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KLO11767.1 - 0.024 13.9 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA PF00004.29 KLO11767.1 - 0.029 14.8 0.0 0.1 13.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KLO11767.1 - 0.088 12.0 0.0 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain CAP PF00188.26 KLO11770.1 - 2.2e-24 86.7 2.0 2.8e-24 86.3 2.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KLO11772.1 - 6.4e-25 88.4 1.2 8.1e-25 88.1 1.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Methyltransf_2 PF00891.18 KLO11773.1 - 9.7e-24 83.8 0.0 1.7e-19 69.9 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain MTS PF05175.14 KLO11773.1 - 0.0022 17.6 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KLO11773.1 - 0.0066 15.6 0.0 0.06 12.4 0.0 2.3 2 1 0 2 2 2 1 DREV methyltransferase LRR_10 PF18805.1 KLO11773.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat Methyltransf_12 PF08242.12 KLO11773.1 - 0.027 15.2 0.0 0.13 13.1 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 KLO11773.1 - 0.052 13.3 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KLO11773.1 - 0.07 13.8 0.1 0.43 11.3 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain F-box-like PF12937.7 KLO11774.1 - 2.6e-07 30.4 0.7 2.6e-07 30.4 0.7 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO11774.1 - 0.018 14.9 3.0 0.13 12.2 3.0 2.4 1 1 0 1 1 1 0 F-box domain Coprogen_oxidas PF01218.18 KLO11775.1 - 1.6e-130 434.2 0.0 1.8e-130 434.0 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase AbiEi_3 PF11459.8 KLO11775.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Septin PF00735.18 KLO11776.1 - 7.5e-47 159.9 0.1 1.5e-17 63.8 0.0 3.8 4 0 0 4 4 4 3 Septin MMR_HSR1 PF01926.23 KLO11776.1 - 8.2e-05 22.7 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KLO11776.1 - 0.0029 17.2 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KLO11776.1 - 0.0099 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KLO11776.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 KLO11776.1 - 0.051 12.7 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KLO11776.1 - 0.06 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KLO11776.1 - 0.12 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain tRNA_synthFbeta PF17759.1 KLO11776.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain RsgA_GTPase PF03193.16 KLO11776.1 - 0.15 11.9 0.1 0.53 10.2 0.1 1.9 1 1 0 1 1 1 0 RsgA GTPase Period_C PF12114.8 KLO11776.1 - 0.64 9.6 4.1 1.8 8.1 2.0 2.4 2 0 0 2 2 2 0 Period protein 2/3C-terminal region CM_2 PF01817.21 KLO11777.1 - 8.6e-05 22.8 0.0 0.23 11.9 0.0 2.6 2 0 0 2 2 2 2 Chorismate mutase type II Thi4 PF01946.17 KLO11778.1 - 4.8e-104 346.7 0.2 6.2e-104 346.4 0.2 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KLO11778.1 - 1.7e-09 37.8 2.1 4.9e-09 36.2 0.7 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO11778.1 - 2.7e-07 30.7 0.1 8.4e-07 29.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO11778.1 - 1.7e-06 27.5 0.1 2.6e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KLO11778.1 - 3.2e-06 26.4 0.6 9.7e-06 24.9 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KLO11778.1 - 5.7e-06 26.4 0.8 6.7e-05 22.9 0.1 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KLO11778.1 - 3e-05 23.3 0.8 0.00014 21.1 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KLO11778.1 - 0.00096 18.0 0.2 0.0017 17.2 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KLO11778.1 - 0.0034 16.8 0.4 0.0059 16.0 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KLO11778.1 - 0.0074 15.4 0.1 0.047 12.8 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KLO11778.1 - 0.0089 15.3 0.1 0.017 14.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KLO11778.1 - 0.036 12.9 0.1 0.056 12.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.6 KLO11778.1 - 0.043 12.9 0.0 0.091 11.9 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KLO11778.1 - 0.12 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase MCRA PF06100.11 KLO11778.1 - 0.19 10.5 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 MCRA family Glyco_hydro_92 PF07971.12 KLO11779.1 - 1.5e-126 423.1 0.0 1.9e-126 422.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KLO11779.1 - 1.4e-54 185.6 0.2 1.9e-54 185.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Glycos_transf_3 PF00591.21 KLO11780.1 - 1e-72 244.8 0.0 1.3e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KLO11780.1 - 3.4e-10 39.6 0.0 5.8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain F-box-like PF12937.7 KLO11781.1 - 9.3e-06 25.4 1.0 3e-05 23.8 1.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO11781.1 - 0.055 13.9 5.0 5.4 7.6 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KLO11781.1 - 0.056 13.4 2.8 0.93 9.4 2.7 3.1 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO11782.1 - 3.1e-06 27.0 1.8 3.8e-05 23.5 0.5 2.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO11782.1 - 0.023 14.6 1.1 0.15 12.0 0.1 2.7 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 KLO11782.1 - 0.11 12.9 0.9 9.1 6.9 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) APH PF01636.23 KLO11783.1 - 2.5e-08 34.1 1.2 5.1e-08 33.1 1.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KLO11783.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase MFS_1 PF07690.16 KLO11784.1 - 2e-25 89.5 50.5 3.3e-23 82.2 37.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.18 KLO11784.1 - 0.00075 18.4 6.8 0.0041 15.9 7.6 1.8 2 0 0 2 2 2 1 Reduced folate carrier Diphthamide_syn PF01866.17 KLO11785.1 - 3.1e-89 299.4 0.0 3.7e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DpnI PF06044.12 KLO11787.1 - 0.017 14.7 0.2 0.021 14.5 0.2 1.1 1 0 0 1 1 1 0 Dam-replacing family Pro-kuma_activ PF09286.11 KLO11791.1 - 8.6e-43 146.0 0.0 3e-42 144.3 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain DUF4693 PF15764.5 KLO11793.1 - 0.061 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4693) HIP1_clath_bdg PF16515.5 KLO11793.1 - 7.4 7.3 6.5 3.2 8.4 1.4 2.9 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Chitin_synth_1 PF01644.17 KLO11794.1 - 5.1e-80 267.2 0.2 7.6e-80 266.6 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KLO11794.1 - 2.6e-29 101.0 0.2 4.4e-28 97.1 0.4 2.7 3 0 0 3 3 3 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KLO11794.1 - 5.3e-23 81.4 1.1 3e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KLO11794.1 - 2.4e-05 24.3 1.4 2.4e-05 24.3 1.4 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 AdoMet_MTase PF07757.13 KLO11796.1 - 9.6e-35 119.3 0.1 2.8e-16 59.9 0.1 2.2 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 KLO11796.1 - 0.092 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KLO11796.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 KLO11796.1 - 0.17 11.7 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain VQ PF05678.14 KLO11797.1 - 0.063 12.8 0.1 0.097 12.2 0.1 1.3 1 0 0 1 1 1 0 VQ motif Glyco_hydro_16 PF00722.21 KLO11798.1 - 0.03 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 Golgin_A5 PF09787.9 KLO11799.1 - 0.00041 19.9 1.5 0.00041 19.9 1.5 1.6 2 0 0 2 2 2 1 Golgin subfamily A member 5 AbiGi PF10899.8 KLO11799.1 - 0.018 14.9 1.2 0.81 9.5 0.1 2.6 2 0 0 2 2 2 0 Putative abortive phage resistance protein AbiGi, antitoxin EF-hand_6 PF13405.6 KLO11799.1 - 0.038 13.9 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 KLO11799.1 - 0.052 13.1 0.1 0.2 11.3 0.1 2.1 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 KLO11799.1 - 0.083 12.4 0.2 0.25 10.9 0.2 1.9 1 0 0 1 1 1 0 EF hand DUF1297 PF06973.12 KLO11799.1 - 0.12 11.9 0.2 0.76 9.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1297) Utp12 PF04003.12 KLO11799.1 - 0.18 12.1 2.4 2.2 8.6 0.1 3.3 3 0 0 3 3 3 0 Dip2/Utp12 Family APG6_N PF17675.1 KLO11799.1 - 0.51 10.9 5.7 0.82 10.2 0.9 3.3 3 1 0 3 3 3 0 Apg6 coiled-coil region EF-hand_6 PF13405.6 KLO11800.1 - 0.054 13.5 0.0 0.31 11.1 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KLO11800.1 - 0.076 12.6 0.1 0.29 10.8 0.1 2.1 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 KLO11800.1 - 0.098 12.2 0.2 0.36 10.4 0.2 2.1 1 0 0 1 1 1 0 EF hand Golgin_A5 PF09787.9 KLO11800.1 - 0.63 9.5 11.1 0.021 14.3 3.9 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 AbiGi PF10899.8 KLO11800.1 - 1.7 8.5 6.6 11 5.8 1.2 2.6 2 1 0 2 2 2 0 Putative abortive phage resistance protein AbiGi, antitoxin adh_short_C2 PF13561.6 KLO11801.1 - 2.4e-36 125.4 0.0 6.1e-36 124.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO11801.1 - 3.4e-36 124.5 0.1 8.4e-36 123.3 0.0 1.6 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KLO11801.1 - 1.4e-06 28.4 0.6 7.4e-06 26.0 0.2 2.0 1 1 1 2 2 2 1 KR domain Pyr_redox PF00070.27 KLO11801.1 - 0.0066 17.0 0.3 0.012 16.1 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 KLO11801.1 - 0.15 11.5 0.1 0.56 9.6 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family MBOAT_2 PF13813.6 KLO11802.1 - 3.1e-14 53.0 3.8 3.1e-14 53.0 3.8 1.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF902 PF06001.13 KLO11804.1 - 0.79 10.3 7.6 17 6.0 3.0 2.9 2 1 0 2 2 2 0 Domain of Unknown Function (DUF902) MFS_1 PF07690.16 KLO11805.1 - 1.2e-05 24.5 0.5 1.6e-05 24.0 0.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Virul_fac_BrkB PF03631.15 KLO11805.1 - 0.052 13.2 4.4 0.065 12.8 4.4 1.1 1 0 0 1 1 1 0 Virulence factor BrkB Wzy_C PF04932.15 KLO11805.1 - 0.31 10.7 3.9 0.5 10.0 3.9 1.3 1 0 0 1 1 1 0 O-Antigen ligase Sun2_CC2 PF18580.1 KLO11806.1 - 0.017 15.3 0.1 0.042 14.1 0.1 1.6 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 CNH PF00780.22 KLO11807.1 - 1.5e-25 90.4 0.0 1.2e-18 67.7 0.0 2.0 2 0 0 2 2 2 2 CNH domain CNH PF00780.22 KLO11808.1 - 1e-22 81.1 0.0 1.4e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 CNH domain DUF4443 PF14544.6 KLO11808.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) zf-C2H2 PF00096.26 KLO11810.1 - 1 10.0 0.0 1 10.0 0.0 3.1 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO11810.1 - 3.7 8.6 4.6 13 6.9 0.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Sacchrp_dh_NADP PF03435.18 KLO11811.1 - 1.1e-05 25.7 0.0 2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KLO11811.1 - 3.1e-05 23.9 0.0 5.9e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KLO11811.1 - 0.00063 19.3 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KLO11811.1 - 0.00078 19.9 0.0 0.0021 18.5 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KLO11811.1 - 0.0025 17.8 0.4 0.011 15.7 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NmrA PF05368.13 KLO11811.1 - 0.0085 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KLO11812.1 - 6.1e-05 22.6 0.0 0.00051 19.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KLO11812.1 - 6.8e-05 23.1 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KLO11812.1 - 0.00066 19.6 0.0 0.00091 19.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KLO11812.1 - 0.0088 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KLO11812.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Tox-HNH-EHHH PF15657.6 KLO11812.1 - 0.21 12.0 1.8 0.35 11.2 1.8 1.3 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxins Sacchrp_dh_NADP PF03435.18 KLO11813.1 - 1.5e-06 28.5 0.1 2.6e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KLO11813.1 - 3.1e-05 23.6 0.2 5.6e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KLO11813.1 - 0.00058 20.3 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KLO11813.1 - 0.0041 16.6 0.0 0.039 13.4 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KLO11813.1 - 0.0096 15.1 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Cytochrom_B562 PF07361.11 KLO11813.1 - 0.076 13.7 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 Cytochrome b562 ICMT PF04140.14 KLO11814.1 - 8.8e-10 38.9 0.1 2.6e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 KLO11814.1 - 6.5e-06 25.8 0.0 7.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KLO11814.1 - 3.3e-05 24.2 0.5 7.2e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KLO11814.1 - 0.0019 17.1 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1686 PF07937.11 KLO11814.1 - 0.083 12.8 0.0 1.2 8.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) 2OG-FeII_Oxy_3 PF13640.6 KLO11815.1 - 1.9e-09 38.3 0.0 3.8e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KLO11815.1 - 0.012 16.3 0.0 0.023 15.4 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pkinase_fungal PF17667.1 KLO11816.1 - 5.1e-19 68.3 0.1 1.2e-11 44.0 0.0 3.1 2 1 0 2 2 2 2 Fungal protein kinase UBA2_C PF16195.5 KLO11816.1 - 0.21 12.3 4.8 0.091 13.5 1.0 2.3 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Pmp3 PF01679.17 KLO11817.1 - 2.3e-19 69.3 10.7 3e-19 68.9 10.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UPF0182 PF03699.13 KLO11820.1 - 0.42 8.7 3.8 0.73 7.9 3.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4345 PF14248.6 KLO11820.1 - 0.9 9.5 6.5 4.8 7.1 0.0 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4345) TPR_10 PF13374.6 KLO11821.1 - 3e-31 106.4 4.6 0.00033 20.4 0.1 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 KLO11821.1 - 7e-22 77.5 10.7 0.0015 18.8 0.0 6.3 2 1 3 5 5 5 5 Tetratricopeptide repeat AAA_16 PF13191.6 KLO11821.1 - 1.2e-07 32.3 0.7 6.2e-07 30.0 0.0 2.6 4 0 0 4 4 3 1 AAA ATPase domain DUF3856 PF12968.7 KLO11821.1 - 8.1e-06 26.0 3.3 0.00097 19.2 0.2 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) NB-ARC PF00931.22 KLO11821.1 - 0.0021 17.3 0.1 0.66 9.1 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain NACHT PF05729.12 KLO11821.1 - 0.005 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.6 KLO11821.1 - 0.0078 16.4 8.0 24 5.5 0.2 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KLO11821.1 - 0.012 15.9 5.2 47 4.7 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Zeta_toxin PF06414.12 KLO11821.1 - 0.065 12.5 0.0 0.26 10.6 0.0 2.0 1 0 0 1 1 1 0 Zeta toxin TPR_2 PF07719.17 KLO11821.1 - 0.1 12.7 5.7 7.3 7.0 0.1 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat AAA_25 PF13481.6 KLO11821.1 - 0.11 12.0 0.0 0.31 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KLO11821.1 - 0.15 12.6 0.1 1 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain TPR_7 PF13176.6 KLO11821.1 - 0.27 11.4 2.2 90 3.5 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4404 PF14357.6 KLO11821.1 - 0.27 11.9 9.4 1.2 9.8 0.2 4.1 6 0 0 6 6 3 0 Domain of unknown function (DUF4404) ANAPC5 PF12862.7 KLO11821.1 - 0.79 9.8 13.8 25 5.0 0.2 6.5 3 1 4 7 7 7 0 Anaphase-promoting complex subunit 5 Pmp3 PF01679.17 KLO11822.1 - 4.9e-19 68.3 11.0 7.5e-19 67.7 11.0 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pmp3 PF01679.17 KLO11823.1 - 1.6e-09 37.8 5.9 2.2e-09 37.3 5.9 1.5 1 1 0 1 1 1 1 Proteolipid membrane potential modulator LKAAEAR PF15478.6 KLO11824.1 - 0.0076 16.5 0.5 0.011 16.0 0.5 1.2 1 0 0 1 1 1 1 Family of unknown function with LKAAEAR motif Pmp3 PF01679.17 KLO11825.1 - 6.8e-13 48.6 1.9 7.8e-13 48.4 1.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pmp3 PF01679.17 KLO11826.1 - 8.6e-16 57.9 6.0 8.6e-16 57.9 6.0 1.8 2 0 0 2 2 2 1 Proteolipid membrane potential modulator FAD_binding_4 PF01565.23 KLO11827.1 - 9e-24 83.8 0.2 2e-23 82.7 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KLO11827.1 - 0.016 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like APH PF01636.23 KLO11828.1 - 8e-15 55.4 0.2 5.1e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Oxidored-like PF09791.9 KLO11829.1 - 3e-18 65.2 0.6 3e-18 65.2 0.6 1.8 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal PCNA_N PF00705.18 KLO11830.1 - 5.8e-51 171.5 3.0 5.6e-50 168.3 1.4 2.3 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KLO11830.1 - 5.4e-39 133.3 0.1 6.2e-18 65.2 0.0 3.2 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 KLO11830.1 - 1.2e-06 27.8 0.3 0.0015 17.6 0.0 3.1 2 1 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 KLO11830.1 - 2.3e-05 24.0 0.0 0.00019 21.0 0.0 2.3 2 1 0 2 2 2 1 Rad9 Hus1 PF04005.12 KLO11830.1 - 0.014 14.5 5.2 0.28 10.2 5.1 3.2 1 1 0 1 1 1 0 Hus1-like protein MDM1 PF15501.6 KLO11830.1 - 0.57 9.3 21.8 0.97 8.5 21.8 1.3 1 0 0 1 1 1 0 Nuclear protein MDM1 Nop14 PF04147.12 KLO11830.1 - 4.4 5.4 36.0 6 4.9 36.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KLO11830.1 - 5.8 6.2 41.7 8.4 5.7 41.7 1.2 1 0 0 1 1 1 0 SDA1 DotU PF09850.9 KLO11831.1 - 0.016 14.9 0.0 0.017 14.9 0.0 1.0 1 0 0 1 1 1 0 Type VI secretion system protein DotU Syndecan PF01034.20 KLO11831.1 - 0.24 11.3 1.4 0.37 10.8 1.4 1.2 1 0 0 1 1 1 0 Syndecan domain Ammonium_transp PF00909.21 KLO11834.1 - 7.6e-114 380.5 27.5 8.8e-114 380.3 27.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family 2OG-FeII_Oxy_3 PF13640.6 KLO11835.1 - 1.2e-10 42.2 0.3 1.6e-09 38.5 0.0 2.8 4 0 0 4 4 4 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KLO11835.1 - 0.014 16.1 0.0 0.034 14.8 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TPR_10 PF13374.6 KLO11838.1 - 1.1e-47 158.7 40.2 1.6e-05 24.6 0.1 12.9 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.6 KLO11838.1 - 2.2e-35 120.8 28.4 0.00045 20.5 0.3 12.7 5 4 8 13 13 13 11 Tetratricopeptide repeat DUF4404 PF14357.6 KLO11838.1 - 3.3e-10 40.5 15.2 1 10.1 0.0 8.9 9 2 1 10 10 8 2 Domain of unknown function (DUF4404) AAA_16 PF13191.6 KLO11838.1 - 1.6e-09 38.3 0.3 1.9e-08 34.9 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain DUF3856 PF12968.7 KLO11838.1 - 1.6e-07 31.5 14.4 0.085 12.9 1.6 5.1 4 2 0 4 4 4 3 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 KLO11838.1 - 8.5e-06 25.8 17.7 2 8.5 0.1 8.9 3 3 5 8 8 7 2 Anaphase-promoting complex subunit 5 NACHT PF05729.12 KLO11838.1 - 2.6e-05 24.2 0.0 6.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_6 PF13174.6 KLO11838.1 - 0.0001 22.7 6.1 33 5.4 0.0 7.5 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF2802 PF10975.8 KLO11838.1 - 0.0078 16.3 0.5 0.064 13.4 0.0 2.9 3 0 0 3 3 1 1 Protein of unknown function (DUF2802) AAA_22 PF13401.6 KLO11838.1 - 0.018 15.3 1.1 3.7 7.8 0.0 4.3 4 1 0 4 4 3 0 AAA domain AAA_18 PF13238.6 KLO11838.1 - 0.025 15.1 0.1 0.3 11.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain Ribonucleas_3_2 PF11469.8 KLO11838.1 - 0.026 14.9 0.7 1.8 9.0 0.0 4.0 3 0 0 3 3 3 0 Ribonuclease III NB-ARC PF00931.22 KLO11838.1 - 0.035 13.3 0.0 0.27 10.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 KLO11838.1 - 0.042 13.1 0.1 0.27 10.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KLO11838.1 - 0.05 13.2 0.1 0.27 10.8 0.1 2.3 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.6 KLO11838.1 - 0.08 13.2 14.7 31 5.1 0.0 8.1 9 0 0 9 9 7 0 Tetratricopeptide repeat Zeta_toxin PF06414.12 KLO11838.1 - 0.14 11.4 0.0 0.53 9.5 0.0 2.0 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 KLO11838.1 - 0.17 11.7 0.0 0.6 10.0 0.0 1.9 1 0 0 1 1 1 0 NTPase AAA PF00004.29 KLO11838.1 - 0.19 12.2 0.6 1.2 9.5 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TPR_17 PF13431.6 KLO11838.1 - 0.47 11.0 23.6 53 4.5 0.2 9.6 10 0 0 10 10 10 0 Tetratricopeptide repeat PUL PF08324.11 KLO11838.1 - 1.5 8.0 16.0 1.4 8.1 0.3 3.9 2 1 2 4 4 4 0 PUL domain Syntaxin-6_N PF09177.11 KLO11838.1 - 1.6 9.3 12.1 1e+02 3.6 0.0 6.4 5 1 2 7 7 6 0 Syntaxin 6, N-terminal Peptidase_M16 PF00675.20 KLO11838.1 - 3.2 7.7 12.9 1.2 9.1 0.2 4.9 3 1 4 7 7 7 0 Insulinase (Peptidase family M16) Spectrin PF00435.21 KLO11838.1 - 4.9 7.7 8.6 25 5.4 0.8 4.7 4 0 0 4 4 4 0 Spectrin repeat MSP1a PF11670.8 KLO11842.1 - 0.095 12.0 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Chromo PF00385.24 KLO11845.1 - 8.8e-12 44.8 1.4 1.1e-11 44.4 1.4 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 KLO11845.1 - 0.067 13.1 0.6 0.14 12.1 0.6 1.6 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF4743 PF15916.5 KLO11846.1 - 0.081 12.9 0.0 0.081 12.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) LUC7 PF03194.15 KLO11847.1 - 5.2e-74 249.1 2.6 6.4e-74 248.8 2.6 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Ank_2 PF12796.7 KLO11848.1 - 9e-20 71.1 0.1 5.7e-10 39.7 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DnaJ PF00226.31 KLO11848.1 - 1.2e-17 63.8 0.0 3.8e-17 62.2 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Ank_4 PF13637.6 KLO11848.1 - 4.4e-14 52.6 0.0 9e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KLO11848.1 - 1.7e-10 40.9 0.0 2.3e-08 34.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KLO11848.1 - 1.1e-08 34.6 0.0 0.00034 20.8 0.0 2.9 3 0 0 3 3 2 2 Ankyrin repeat Ank PF00023.30 KLO11848.1 - 3.9e-05 23.9 0.0 0.0074 16.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat NPR3 PF03666.13 KLO11848.1 - 0.2 10.4 10.7 0.33 9.7 10.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 KLO11848.1 - 0.56 10.0 16.1 1.1 9.0 16.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TAF4 PF05236.14 KLO11848.1 - 1.2 8.8 21.1 2.7 7.7 21.1 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Neur_chan_memb PF02932.16 KLO11848.1 - 1.6 8.7 5.7 3.5 7.6 5.7 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.16 KLO11848.1 - 1.7 7.5 3.7 2.3 7.0 3.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.11 KLO11848.1 - 2.7 6.4 20.5 3.8 5.9 20.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 KLO11848.1 - 2.7 6.7 17.9 4.1 6.1 17.9 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 KLO11848.1 - 3.4 4.7 6.5 4.2 4.4 6.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4554 PF15091.6 KLO11848.1 - 4.7 6.0 10.1 7.5 5.3 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Exo_endo_phos PF03372.23 KLO11849.1 - 9.7e-15 54.7 0.0 1.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Tudor_3 PF18115.1 KLO11850.1 - 8.7e-10 38.3 0.1 2.1e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 KLO11850.1 - 3.4e-05 23.4 0.0 5.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 DUF1325 PF07039.11 KLO11850.1 - 0.00098 19.2 0.1 0.0021 18.1 0.1 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain BRCT PF00533.26 KLO11850.1 - 0.00099 19.4 0.0 0.0087 16.4 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF4537 PF15057.6 KLO11850.1 - 0.0011 18.9 0.0 0.0032 17.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF2341 PF10102.9 KLO11850.1 - 0.031 14.8 0.0 0.077 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) 53-BP1_Tudor PF09038.10 KLO11850.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor APG6_N PF17675.1 KLO11851.1 - 0.022 15.3 3.0 0.045 14.3 3.0 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region FlgN PF05130.12 KLO11851.1 - 4 7.9 8.0 5.7 7.4 4.7 2.3 2 0 0 2 2 2 0 FlgN protein WBS_methylT PF12589.8 KLO11854.1 - 5.2e-24 84.8 8.9 8.4e-24 84.1 8.9 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KLO11854.1 - 1.6e-09 38.2 0.0 3.1e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO11854.1 - 3.5e-08 34.0 0.0 7.5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO11854.1 - 2.7e-05 24.8 0.0 7.5e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO11854.1 - 5.3e-05 23.1 0.0 8.5e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO11854.1 - 0.00066 19.5 0.0 0.0017 18.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KLO11854.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PCMT PF01135.19 KLO11854.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KLO11854.1 - 0.2 11.7 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TRAPP PF04051.16 KLO11855.1 - 3.6e-37 127.3 0.0 4.7e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Vac_ImportDeg PF09783.9 KLO11857.1 - 8.6e-54 181.7 0.0 3.2e-53 179.8 0.0 1.8 1 1 0 1 1 1 1 Vacuolar import and degradation protein NAD_binding_8 PF13450.6 KLO11858.1 - 3.7e-12 46.3 0.0 8.8e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KLO11858.1 - 2.3e-09 36.9 0.1 3.9e-08 32.8 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KLO11858.1 - 5.1e-09 35.1 0.3 1.7e-08 33.4 0.1 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KLO11858.1 - 5e-07 29.2 0.0 9.3e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO11858.1 - 2.9e-06 26.8 1.1 3.4e-05 23.3 0.1 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO11858.1 - 0.00012 21.8 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KLO11858.1 - 0.0043 16.3 0.1 0.01 15.1 0.1 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KLO11858.1 - 0.015 14.4 0.1 0.04 13.0 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KLO11858.1 - 0.097 11.7 0.2 12 4.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KLO11858.1 - 0.11 11.7 0.2 0.18 11.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pkinase PF00069.25 KLO11859.1 - 3.3e-27 95.5 0.0 4e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO11859.1 - 4.5e-13 49.1 0.0 6e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO11859.1 - 2.9e-07 29.6 0.0 4.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO11859.1 - 0.036 14.0 0.3 8.6 6.2 0.0 2.5 2 1 0 3 3 3 0 Phosphotransferase enzyme family JmjC PF02373.22 KLO11861.1 - 1.3e-07 32.1 0.0 2.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-RING_5 PF14634.6 KLO11863.1 - 3.7e-09 36.4 7.1 4.9e-09 36.0 7.1 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KLO11863.1 - 0.87 9.5 9.3 0.17 11.8 5.3 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 G-patch_2 PF12656.7 KLO11864.1 - 7e-22 77.3 0.1 2.6e-21 75.5 0.1 2.1 1 0 0 1 1 1 1 G-patch domain ATP-synt_D PF01813.17 KLO11865.1 - 5.4e-70 235.2 3.4 6.8e-70 234.9 3.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 KLO11865.1 - 0.026 14.1 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) Methyltransf_11 PF08241.12 KLO11866.1 - 8.9e-12 45.5 0.0 1.7e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO11866.1 - 1.2e-11 44.7 0.0 2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO11866.1 - 1.5e-11 44.3 0.0 1.8e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO11866.1 - 1.1e-09 38.9 0.0 3.5e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO11866.1 - 4.2e-08 33.8 0.0 1.4e-07 32.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO11866.1 - 0.00015 21.4 0.0 0.0036 16.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KLO11866.1 - 0.00061 19.3 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 KLO11866.1 - 0.0028 17.8 0.0 0.0044 17.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 KLO11866.1 - 0.037 13.4 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 KLO11866.1 - 0.04 13.2 0.0 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Ubie_methyltran PF01209.18 KLO11866.1 - 0.052 12.9 0.0 8.6 5.6 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KLO11866.1 - 0.057 12.0 0.0 5.2 5.5 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 KLO11866.1 - 0.14 11.4 0.0 0.91 8.8 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain FRG1 PF06229.12 KLO11867.1 - 7.7e-20 71.4 4.0 9.1e-20 71.2 0.1 2.4 3 0 0 3 3 3 1 FRG1-like domain Fascin PF06268.13 KLO11867.1 - 0.00017 21.8 0.0 0.00069 19.8 0.0 2.0 2 0 0 2 2 2 1 Fascin domain UBA2_C PF16195.5 KLO11867.1 - 7.6 7.3 10.0 2.3 9.0 6.0 2.3 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus BCS1_N PF08740.11 KLO11868.1 - 1.7e-48 165.1 2.6 2.4e-48 164.6 2.6 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KLO11868.1 - 8.3e-20 71.6 0.0 1.6e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KLO11868.1 - 7.2e-05 23.2 0.5 0.00053 20.4 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KLO11868.1 - 0.00048 19.8 0.0 0.0058 16.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KLO11868.1 - 0.0016 18.6 0.2 0.013 15.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KLO11868.1 - 0.0059 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 KLO11868.1 - 0.0087 15.2 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KLO11868.1 - 0.012 15.9 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KLO11868.1 - 0.014 15.4 0.1 0.078 13.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KLO11868.1 - 0.016 15.7 0.0 0.032 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KLO11868.1 - 0.047 13.2 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KLO11868.1 - 0.052 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KLO11868.1 - 0.058 13.7 0.0 0.24 11.7 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 KLO11868.1 - 0.077 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KLO11868.1 - 0.078 12.9 0.0 1.5 8.7 0.0 2.2 1 1 1 2 2 2 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 KLO11868.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 KLO11868.1 - 0.15 12.6 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TIP39 PF14980.6 KLO11868.1 - 0.42 10.5 4.2 7.9 6.4 0.3 3.7 3 0 0 3 3 3 0 TIP39 peptide Ras PF00071.22 KLO11869.1 - 8.7e-51 171.7 0.0 1e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO11869.1 - 9.8e-31 106.5 0.0 1.7e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO11869.1 - 7.9e-11 41.7 0.0 1.1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KLO11869.1 - 0.00043 19.7 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KLO11869.1 - 0.00071 19.6 0.0 0.0013 18.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KLO11869.1 - 0.0024 17.1 1.4 0.19 10.9 0.1 2.9 2 1 1 3 3 3 1 G-protein alpha subunit RNA_helicase PF00910.22 KLO11869.1 - 0.01 16.2 0.1 0.17 12.3 0.1 2.1 1 1 0 1 1 1 0 RNA helicase DUF3426 PF11906.8 KLO11869.1 - 0.011 15.9 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) Pox_A32 PF04665.12 KLO11869.1 - 0.019 14.4 0.1 0.032 13.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KLO11869.1 - 0.033 13.7 0.1 0.059 12.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DAP3 PF10236.9 KLO11869.1 - 0.047 12.9 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 KLO11869.1 - 0.064 13.0 0.2 0.12 12.1 0.1 1.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KLO11869.1 - 0.068 13.1 0.1 13 5.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 KLO11869.1 - 0.077 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KLO11869.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KLO11869.1 - 0.094 12.0 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 KLO11869.1 - 0.14 12.5 0.1 0.31 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Ribosomal_S13 PF00416.22 KLO11870.1 - 4.4e-24 85.3 0.0 6.1e-12 46.0 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein S13/S18 FbpA PF05833.11 KLO11870.1 - 0.00018 20.4 0.0 0.00022 20.1 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) IMS_HHH PF11798.8 KLO11870.1 - 0.021 15.1 0.0 0.057 13.8 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif FAM70 PF14967.6 KLO11870.1 - 0.08 12.4 0.8 0.099 12.1 0.8 1.1 1 0 0 1 1 1 0 FAM70 protein XAP5 PF04921.14 KLO11871.1 - 3.7e-84 282.5 12.6 3.7e-84 282.5 12.6 2.4 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF2052 PF09747.9 KLO11871.1 - 0.47 10.6 18.8 0.82 9.8 18.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4604 PF15377.6 KLO11871.1 - 1.2 9.5 21.2 0.07 13.5 13.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF4407 PF14362.6 KLO11871.1 - 6 6.1 17.4 7.4 5.8 12.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) JmjC PF02373.22 KLO11872.1 - 1.4e-09 38.4 0.0 5.9e-09 36.4 0.0 2.1 1 1 1 2 2 2 1 JmjC domain, hydroxylase OrfB_Zn_ribbon PF07282.11 KLO11872.1 - 0.0055 16.6 0.3 0.021 14.7 0.3 2.0 1 0 0 1 1 1 1 Putative transposase DNA-binding domain C1_2 PF03107.16 KLO11872.1 - 0.009 16.3 4.6 0.022 15.0 4.6 1.7 1 0 0 1 1 1 1 C1 domain PolC_DP2 PF03833.13 KLO11872.1 - 0.11 10.4 0.7 0.15 9.9 0.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C5HC2 PF02928.16 KLO11872.1 - 0.13 12.6 4.3 0.32 11.4 4.3 1.7 1 0 0 1 1 1 0 C5HC2 zinc finger zf-C3HC4_3 PF13920.6 KLO11873.1 - 0.0018 18.1 6.7 0.029 14.2 3.0 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO11873.1 - 0.0086 15.9 4.5 0.041 13.7 0.8 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KLO11873.1 - 0.01 15.8 6.1 0.082 12.9 1.3 2.3 2 0 0 2 2 2 0 zinc-RING finger domain FpoO PF10621.9 KLO11873.1 - 0.02 15.2 0.5 0.045 14.1 0.2 1.7 1 1 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO zf-RING_10 PF16685.5 KLO11873.1 - 0.029 14.5 2.1 0.029 14.5 2.1 1.7 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 KLO11873.1 - 0.039 13.8 3.8 0.63 9.9 0.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO11873.1 - 0.043 13.7 6.3 0.23 11.4 2.7 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 KLO11873.1 - 0.049 13.9 1.7 2.3 8.6 0.2 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-P11 PF03854.14 KLO11873.1 - 0.085 12.5 2.9 0.25 11.0 0.4 2.2 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_2 PF13639.6 KLO11873.1 - 0.097 13.0 6.2 1.1 9.7 1.4 2.3 2 0 0 2 2 2 0 Ring finger domain Pput2613-deam PF14427.6 KLO11873.1 - 0.17 11.8 0.4 0.17 11.8 0.4 1.9 1 1 1 2 2 2 0 Pput_2613-like deaminase Anti-TRAP PF15777.5 KLO11873.1 - 0.24 11.4 3.1 0.46 10.5 1.0 2.1 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_4 PF14570.6 KLO11873.1 - 0.33 10.8 5.1 2.3 8.1 1.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_15 PF17032.5 KLO11873.1 - 0.38 11.5 5.5 0.91 10.3 5.5 1.7 1 1 0 1 1 1 0 zinc-ribbon family Prim_Zn_Ribbon PF08273.12 KLO11873.1 - 0.71 10.2 0.2 0.71 10.2 0.2 2.7 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase DnaJ_CXXCXGXG PF00684.19 KLO11873.1 - 0.8 10.1 8.4 0.36 11.2 1.7 2.4 1 1 1 2 2 2 0 DnaJ central domain zf-TFIIB PF13453.6 KLO11873.1 - 1.9 7.9 8.9 8.2 5.9 0.2 3.5 3 1 0 3 3 3 0 Transcription factor zinc-finger TF_Zn_Ribbon PF08271.12 KLO11873.1 - 2.5 7.7 9.6 0.41 10.2 0.7 2.7 2 1 0 2 2 2 0 TFIIB zinc-binding DUF3797 PF12677.7 KLO11873.1 - 3.3 7.7 6.1 3.1 7.8 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) Ribosomal_L26 PF16906.5 KLO11874.1 - 1.3e-36 124.9 3.0 1.9e-36 124.3 3.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KLO11874.1 - 6.4e-10 38.6 2.2 6.4e-10 38.6 2.2 1.8 2 0 0 2 2 2 1 KOW motif Phage_holin_3_3 PF16083.5 KLO11875.1 - 0.084 13.0 3.5 0.19 11.8 0.3 2.8 3 0 0 3 3 3 0 LydA holin phage, holin superfamily III DUF2157 PF09925.9 KLO11876.1 - 0.012 15.4 2.6 0.066 13.0 0.2 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) XK-related PF09815.9 KLO11876.1 - 0.042 12.9 0.1 0.042 12.9 0.1 2.0 2 0 0 2 2 2 0 XK-related protein SLATT_6 PF18169.1 KLO11876.1 - 0.052 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Y_phosphatase3 PF13350.6 KLO11877.1 - 3.7e-61 207.1 0.0 4.2e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KLO11877.1 - 1.8e-05 24.4 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KLO11877.1 - 0.00037 20.1 0.0 0.00053 19.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 KLO11877.1 - 0.00051 19.1 0.0 0.00084 18.4 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 KLO11877.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain SMBP PF16785.5 KLO11880.1 - 0.028 14.6 0.5 8.2 6.7 0.1 2.3 1 1 0 2 2 2 0 Small metal-binding protein Av_adeno_fibre PF06536.11 KLO11880.1 - 0.74 9.7 7.4 86 3.1 0.1 5.5 1 1 4 6 6 6 0 Avian adenovirus fibre, N-terminal Lamprin PF06403.11 KLO11880.1 - 2.7 8.0 12.1 8.1e+02 -0.1 12.1 2.8 1 1 0 1 1 1 0 Lamprin PfUIS3 PF11567.8 KLO11882.1 - 0.0025 18.2 0.2 0.0042 17.4 0.2 1.3 1 0 0 1 1 1 1 Plasmodium falciparum UIS3 membrane protein Lon_2 PF13337.6 KLO11882.1 - 0.04 12.5 0.1 0.055 12.0 0.1 1.1 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease DUF4315 PF14193.6 KLO11883.1 - 0.054 13.5 1.2 0.14 12.2 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) KxDL PF10241.9 KLO11884.1 - 0.12 12.6 1.4 0.22 11.8 1.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein LEA_2 PF03168.13 KLO11885.1 - 8.5e-07 29.4 0.0 1.6e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.12 KLO11885.1 - 0.00078 18.8 2.5 0.0011 18.3 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Vac7 PF12751.7 KLO11885.1 - 0.0014 18.1 0.0 0.0019 17.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 Sen15 PF09631.10 KLO11886.1 - 7.1e-19 68.0 0.0 9.4e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein UFD1 PF03152.14 KLO11887.1 - 1.4e-68 229.7 0.0 1.8e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 KLO11887.1 - 0.042 13.6 0.0 0.59 9.9 0.0 2.3 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Ribosomal_60s PF00428.19 KLO11887.1 - 4.7 7.9 7.3 31 5.2 0.1 2.5 1 1 1 2 2 2 0 60s Acidic ribosomal protein Cpn60_TCP1 PF00118.24 KLO11888.1 - 5.7e-147 490.3 12.8 6.4e-147 490.1 12.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ThiF PF00899.21 KLO11889.1 - 3.3e-65 219.8 0.0 4.8e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KLO11889.1 - 8.4e-25 86.7 0.3 1.4e-24 86.1 0.3 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KLO11889.1 - 0.0045 17.0 0.1 0.011 15.8 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KLO11889.1 - 0.034 14.7 0.1 0.068 13.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KLO11889.1 - 0.058 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglD_N PF17836.1 KLO11889.1 - 0.088 13.5 0.1 0.24 12.0 0.1 1.8 1 0 0 1 1 1 0 PglD N-terminal domain Gly_kinase PF02595.15 KLO11889.1 - 0.12 11.4 0.0 0.34 9.8 0.0 1.7 2 0 0 2 2 2 0 Glycerate kinase family Sacchrp_dh_NADP PF03435.18 KLO11889.1 - 0.29 11.4 0.9 0.82 9.9 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ecm33 PF12454.8 KLO11889.1 - 0.34 11.1 3.0 0.74 10.0 3.0 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Mito_carr PF00153.27 KLO11890.1 - 6.4e-47 157.4 0.2 2.9e-15 56.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S28e PF01200.18 KLO11891.1 - 6.5e-30 102.9 2.0 7.2e-30 102.8 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Torus PF16131.5 KLO11892.1 - 9.3e-08 32.7 0.0 1.6e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KLO11892.1 - 3.7e-06 26.8 1.7 1e-05 25.4 1.7 1.8 1 0 0 1 1 1 1 Zinc finger domain RRM_1 PF00076.22 KLO11892.1 - 1.1e-05 25.1 0.0 6.6e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 KLO11892.1 - 0.00067 19.5 1.8 0.0016 18.3 1.8 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KLO11892.1 - 0.003 17.7 0.4 0.0077 16.4 0.1 1.8 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KLO11892.1 - 0.0045 17.4 1.5 0.0099 16.3 1.5 1.6 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KLO11892.1 - 0.017 15.0 1.7 0.045 13.6 1.7 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger FYVE PF01363.21 KLO11892.1 - 0.47 10.6 5.6 0.11 12.7 2.2 1.9 2 1 0 2 2 2 0 FYVE zinc finger Cript PF10235.9 KLO11892.1 - 6.2 7.5 10.2 1.1 9.9 0.9 2.7 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT LEA_2 PF03168.13 KLO11893.1 - 7.1e-08 32.9 0.0 1.8e-07 31.6 0.0 1.7 1 1 1 2 2 2 1 Late embryogenesis abundant protein DUF1356 PF07092.12 KLO11893.1 - 0.0009 18.6 0.3 0.0013 18.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Rrn6 PF10214.9 KLO11894.1 - 2.6e-15 56.0 3.9 3.9e-09 35.6 1.6 3.6 3 1 0 3 3 3 3 RNA polymerase I-specific transcription-initiation factor NPR2 PF06218.11 KLO11895.1 - 3.8e-100 335.7 9.7 2.1e-84 283.8 7.0 3.1 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Orexin_rec2 PF03827.13 KLO11896.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Orexin receptor type 2 TYW3 PF02676.14 KLO11896.1 - 0.11 11.9 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Methyltransferase TYW3 PocR PF10114.9 KLO11897.1 - 0.36 10.6 1.8 0.55 10.0 1.8 1.2 1 0 0 1 1 1 0 Sensory domain found in PocR Zn_clus PF00172.18 KLO11897.1 - 0.69 10.1 13.9 4.5 7.5 13.8 2.0 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO11898.1 - 3e-06 27.2 6.9 3.9e-06 26.9 6.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 KLO11898.1 - 0.094 11.7 0.1 0.097 11.7 0.1 1.0 1 0 0 1 1 1 0 Clusterin RTC PF01137.21 KLO11899.1 - 1.1e-57 194.8 0.0 1.2e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KLO11899.1 - 1.1e-34 119.0 0.0 1.6e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF3759 PF12585.8 KLO11900.1 - 9.4e-06 25.6 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Plavaka PF18759.1 KLO11904.1 - 1.4e-121 405.7 0.0 1.8e-121 405.3 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF3759 PF12585.8 KLO11906.1 - 7.6e-06 25.9 0.1 1.2e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) NmrA PF05368.13 KLO11907.1 - 3.4e-33 115.2 0.0 4.6e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO11907.1 - 2e-14 53.9 0.0 6.4e-14 52.3 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KLO11907.1 - 5.8e-06 26.6 0.0 2.3e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KLO11907.1 - 0.00037 20.5 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO11907.1 - 0.00042 19.8 0.1 0.0019 17.7 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 KLO11907.1 - 0.026 14.9 0.0 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KLO11907.1 - 0.033 14.3 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KLO11907.1 - 0.042 14.4 0.0 0.13 12.8 0.0 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KLO11907.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 KLO11907.1 - 0.063 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KLO11907.1 - 0.077 13.4 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KLO11907.1 - 0.096 12.1 0.2 0.56 9.5 0.0 2.1 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Dicistro_VP4 PF11492.8 KLO11907.1 - 0.096 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 NmrA PF05368.13 KLO11908.1 - 1.8e-34 119.3 0.0 2.6e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO11908.1 - 2.3e-16 60.2 0.1 8.6e-16 58.4 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KLO11908.1 - 4.4e-05 23.7 0.1 0.00016 21.9 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KLO11908.1 - 0.0067 16.4 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO11908.1 - 0.013 15.0 0.1 0.087 12.3 0.1 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KLO11908.1 - 0.014 15.5 0.4 0.072 13.2 0.4 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KLO11908.1 - 0.021 13.9 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UBD PF16455.5 KLO11908.1 - 0.074 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-binding domain TrkA_N PF02254.18 KLO11908.1 - 0.1 12.9 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain DUF1576 PF07613.11 KLO11908.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) DUF3889 PF13028.6 KLO11910.1 - 0.69 9.9 0.1 0.69 9.9 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3889) UPF0240 PF06784.11 KLO11911.1 - 0.0054 16.8 0.3 0.006 16.7 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) SID-1_RNA_chan PF13965.6 KLO11912.1 - 0.051 12.0 0.4 0.061 11.7 0.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3043 PF11241.8 KLO11913.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Sen15 PF09631.10 KLO11916.1 - 2.3e-17 63.1 0.0 3.1e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein NmrA PF05368.13 KLO11918.1 - 1.1e-34 120.1 0.0 1.5e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO11918.1 - 5.3e-15 55.8 0.3 1.6e-14 54.2 0.3 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KLO11918.1 - 7.1e-07 29.5 0.1 1.6e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KLO11918.1 - 0.00022 21.2 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO11918.1 - 0.0013 18.2 0.2 0.0073 15.8 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KLO11918.1 - 0.028 14.5 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 KLO11918.1 - 0.036 13.1 0.1 0.059 12.4 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KLO11918.1 - 0.068 13.4 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 KLO11918.1 - 0.094 13.3 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pkinase_Tyr PF07714.17 KLO11919.1 - 9.2e-38 130.0 0.0 1.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO11919.1 - 1.4e-35 123.0 0.0 2.3e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KLO11919.1 - 0.00098 18.0 0.1 0.0029 16.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KLO11919.1 - 0.037 13.3 0.0 0.097 12.0 0.0 1.6 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KLO11919.1 - 0.037 13.9 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NmrA PF05368.13 KLO11922.1 - 1.4e-29 103.3 0.0 1.9e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO11922.1 - 3.9e-15 56.2 0.0 1.4e-14 54.5 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KLO11922.1 - 7e-05 23.1 0.0 0.00082 19.6 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KLO11922.1 - 0.0069 16.9 0.0 0.036 14.6 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 KLO11922.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KLO11922.1 - 0.025 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KLO11922.1 - 0.069 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KLO11922.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Dna2 PF08696.11 KLO11924.1 - 1.1e-59 201.7 0.0 1.9e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KLO11924.1 - 1.7e-51 174.7 0.0 2.6e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KLO11924.1 - 4.3e-14 52.9 0.0 1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KLO11924.1 - 2e-08 34.2 0.0 3.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 KLO11924.1 - 2.6e-07 30.8 0.0 7.6e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.6 KLO11924.1 - 3.5e-07 30.7 0.0 7.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 KLO11924.1 - 0.00011 22.4 0.2 0.0007 19.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KLO11924.1 - 0.0012 18.7 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KLO11924.1 - 0.0023 18.4 0.1 0.0097 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain UvrD-helicase PF00580.21 KLO11924.1 - 0.0078 15.8 0.1 0.017 14.7 0.1 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 KLO11924.1 - 0.013 16.0 0.0 0.037 14.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 KLO11924.1 - 0.013 15.1 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KLO11924.1 - 0.018 15.6 0.1 0.41 11.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KLO11924.1 - 0.032 14.5 0.3 0.18 12.0 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KLO11924.1 - 0.043 13.3 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MeaB PF03308.16 KLO11924.1 - 0.051 12.5 0.0 0.098 11.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Helicase_RecD PF05127.14 KLO11924.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Helicase NTPase_1 PF03266.15 KLO11924.1 - 0.068 13.1 0.3 0.15 12.0 0.3 1.5 1 0 0 1 1 1 0 NTPase RuvB_N PF05496.12 KLO11924.1 - 0.13 12.0 0.6 0.26 11.0 0.1 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain UvrD_C_2 PF13538.6 KLO11924.1 - 0.16 11.8 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ThiF PF00899.21 KLO11925.1 - 5e-11 42.4 0.0 2e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 ThiF family Chalcone_2 PF16035.5 KLO11925.1 - 0.065 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Chalcone isomerase like Rad17 PF03215.15 KLO11926.1 - 3.7e-27 95.5 0.0 6.5e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KLO11926.1 - 0.00064 20.1 0.0 0.0023 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 KLO11926.1 - 0.0091 16.3 0.0 0.036 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA C-terminal domain AAA PF00004.29 KLO11926.1 - 0.011 16.2 0.0 0.043 14.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KLO11926.1 - 0.083 12.6 0.1 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KLO11926.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 KLO11929.1 - 0.0004 20.7 16.3 0.001 19.4 1.2 4.1 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO11929.1 - 0.019 15.8 13.3 0.16 12.9 0.6 3.9 4 1 0 4 4 4 0 C2H2-type zinc finger Zap1_zf2 PF18217.1 KLO11929.1 - 0.63 10.1 4.9 4.7 7.3 0.7 2.7 2 0 0 2 2 2 0 Zap1 zinc finger 2 LBP_C PF17386.2 KLO11930.1 - 0.0053 16.6 0.1 0.68 9.9 0.0 2.4 2 0 0 2 2 2 2 Lacto-N-biose phosphorylase C-terminal domain NmrA PF05368.13 KLO11933.1 - 6.5e-34 117.5 0.0 8.3e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO11933.1 - 5.7e-17 62.2 0.1 4.7e-16 59.2 0.1 2.2 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KLO11933.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO11933.1 - 0.0061 16.0 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KLO11933.1 - 0.026 15.0 0.1 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KLO11933.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 KLO11934.1 - 1e-32 113.6 0.1 1.3e-32 113.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO11934.1 - 2.9e-16 59.9 1.4 1.5e-15 57.6 1.4 2.1 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KLO11934.1 - 0.0015 18.5 0.1 0.0023 17.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO11934.1 - 0.0036 16.8 0.1 0.011 15.2 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KLO11934.1 - 0.0042 17.5 0.2 0.0082 16.6 0.2 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KLO11934.1 - 0.037 14.2 0.2 0.068 13.3 0.2 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KLO11934.1 - 0.062 12.3 0.2 0.1 11.6 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KLO11935.1 - 1.8e-30 106.2 0.0 2.6e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO11935.1 - 9.3e-15 55.0 0.1 1.5e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KLO11935.1 - 1.1e-05 25.7 0.5 3.4e-05 24.1 0.4 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KLO11935.1 - 0.00014 21.8 0.1 0.00027 20.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO11935.1 - 0.0067 15.9 0.2 0.02 14.4 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KLO11935.1 - 0.028 15.0 1.4 0.085 13.5 0.2 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 KLO11935.1 - 0.085 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 KLO11935.1 - 0.13 11.5 0.9 0.22 10.8 0.9 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MoCF_biosynth PF00994.24 KLO11935.1 - 0.51 10.0 3.9 0.74 9.5 0.9 2.4 1 1 1 2 2 2 0 Probable molybdopterin binding domain Tetraspanin PF00335.20 KLO11936.1 - 2.6e-08 33.9 7.9 4.1e-08 33.2 7.9 1.3 1 0 0 1 1 1 1 Tetraspanin family YwcE PF17368.2 KLO11937.1 - 7.9 7.2 11.9 0.41 11.3 0.8 3.1 3 1 0 3 3 3 0 Spore morphogenesis and germination YwcE Aldo_ket_red PF00248.21 KLO11939.1 - 1.1e-42 146.3 0.0 3.2e-41 141.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family IGPS PF00218.21 KLO11940.1 - 1.7e-88 296.1 0.0 2e-88 295.9 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.19 KLO11940.1 - 0.0024 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 KLO11940.1 - 0.032 13.4 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KLO11940.1 - 0.097 12.1 0.1 0.28 10.6 0.0 1.8 2 1 0 2 2 2 0 Histidine biosynthesis protein ESX-1_EspG PF14011.6 KLO11940.1 - 0.14 11.8 1.8 0.25 10.9 0.2 1.9 1 1 1 2 2 2 0 EspG family NmrA PF05368.13 KLO11941.1 - 2.3e-31 109.2 0.0 3.1e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO11941.1 - 6.5e-14 52.2 0.1 1.4e-13 51.2 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KLO11941.1 - 1.5e-05 25.2 0.1 0.00073 19.8 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KLO11941.1 - 2.6e-05 24.2 0.1 4.6e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KLO11941.1 - 0.0032 18.0 0.0 0.0079 16.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 KLO11941.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KLO11941.1 - 0.014 15.8 0.0 0.056 13.9 0.1 1.9 3 0 0 3 3 3 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KLO11941.1 - 0.095 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UBD PF16455.5 KLO11941.1 - 0.096 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-binding domain Epimerase PF01370.21 KLO11941.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ATG27 PF09451.10 KLO11942.1 - 5.4e-15 56.0 0.0 7.9e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KLO11942.1 - 0.073 13.1 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 KLO11943.1 - 1.1e-06 28.7 0.0 1.3e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KLO11943.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat Totivirus_coat PF05518.11 KLO11950.1 - 1.2 7.1 4.4 1.9 6.4 4.4 1.2 1 0 0 1 1 1 0 Totivirus coat protein Peptidase_C48 PF02902.19 KLO11951.1 - 4.5e-12 46.3 0.2 7.6e-12 45.5 0.2 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HTH_21 PF13276.6 KLO11955.1 - 0.00073 19.6 0.0 0.16 12.1 0.0 2.6 2 0 0 2 2 2 2 HTH-like domain Alpha_kinase PF02816.18 KLO11956.1 - 0.00037 20.7 0.0 0.00043 20.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Dynamin_N PF00350.23 KLO11957.1 - 6.4e-19 68.6 0.3 5.6e-18 65.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KLO11957.1 - 4e-07 30.1 0.5 2.6e-05 24.2 0.1 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KLO11957.1 - 2e-05 25.1 0.5 9.3e-05 23.0 0.0 2.3 1 1 1 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KLO11957.1 - 4.3e-05 23.5 0.1 0.00014 21.8 0.0 1.9 2 0 0 2 2 1 1 RsgA GTPase AAA_22 PF13401.6 KLO11957.1 - 0.00026 21.3 0.2 0.016 15.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KLO11957.1 - 0.0013 19.3 0.2 0.0013 19.3 0.2 2.9 3 1 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KLO11957.1 - 0.002 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KLO11957.1 - 0.0023 18.4 2.6 0.009 16.4 0.0 3.1 2 2 1 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 KLO11957.1 - 0.0032 16.7 0.0 0.0084 15.3 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain TsaE PF02367.17 KLO11957.1 - 0.007 16.4 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KLO11957.1 - 0.0071 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 KLO11957.1 - 0.018 14.2 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.13 KLO11957.1 - 0.023 13.9 0.0 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AIG1 PF04548.16 KLO11957.1 - 0.035 13.4 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Parvo_NS1 PF01057.17 KLO11957.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IIGP PF05049.13 KLO11957.1 - 0.075 12.1 0.1 0.57 9.2 0.1 2.2 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Septin PF00735.18 KLO11957.1 - 0.11 11.7 0.0 0.28 10.4 0.0 1.7 1 0 0 1 1 1 0 Septin DUF87 PF01935.17 KLO11957.1 - 0.11 12.5 6.6 0.33 11.0 0.0 3.6 4 1 0 4 4 4 0 Helicase HerA, central domain GTP_EFTU PF00009.27 KLO11957.1 - 0.12 11.9 0.2 0.54 9.8 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 KLO11957.1 - 0.15 12.5 0.0 0.56 10.6 0.0 2.1 1 1 0 1 1 1 0 RNA helicase AAA_21 PF13304.6 KLO11957.1 - 0.23 11.2 0.9 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system KAP_NTPase PF07693.14 KLO11957.1 - 1.9 7.7 4.4 3.1 6.9 4.4 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Cys_Met_Meta_PP PF01053.20 KLO11958.1 - 3.1e-145 483.5 0.0 3.5e-145 483.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KLO11958.1 - 3.4e-12 46.3 0.7 3.7e-11 42.9 0.4 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KLO11958.1 - 2.1e-11 43.6 0.1 3.1e-11 43.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KLO11958.1 - 8e-09 34.9 0.3 1.3e-08 34.2 0.3 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KLO11958.1 - 1.5e-05 24.4 0.0 3.2e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KLO11958.1 - 0.0045 15.6 0.1 0.0064 15.1 0.1 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 KLO11958.1 - 0.063 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Dynamin_N PF00350.23 KLO11959.1 - 1.7e-19 70.5 1.8 2.5e-18 66.7 0.0 3.3 2 1 1 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KLO11959.1 - 3.6e-07 30.3 0.1 0.00059 19.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO11959.1 - 7.8e-06 25.9 0.2 0.00041 20.3 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KLO11959.1 - 0.019 15.3 2.9 0.075 13.4 0.0 3.3 3 1 1 4 4 4 0 AAA ATPase domain ABC_tran PF00005.27 KLO11959.1 - 0.02 15.4 2.4 0.028 14.9 0.0 2.5 2 1 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.14 KLO11959.1 - 0.027 13.7 0.1 0.056 12.7 0.1 1.6 1 1 0 1 1 1 0 KAP family P-loop domain ABC_tran_CTD PF16326.5 KLO11959.1 - 0.084 13.1 8.7 0.42 10.9 0.5 3.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain AAA_23 PF13476.6 KLO11959.1 - 0.087 13.3 10.3 0.53 10.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KLO11959.1 - 0.11 12.9 0.2 2.5 8.5 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KLO11959.1 - 0.15 11.8 2.1 0.5 10.1 0.0 2.7 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AIG1 PF04548.16 KLO11959.1 - 0.21 10.9 1.9 0.49 9.7 0.0 2.3 2 0 0 2 2 2 0 AIG1 family DUF4011 PF13195.6 KLO11959.1 - 1.1 9.2 9.8 2.3 8.1 8.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) RHH_4 PF13467.6 KLO11959.1 - 1.3 9.0 3.1 4.5 7.2 0.0 3.2 3 0 0 3 3 3 0 Ribbon-helix-helix domain Noelin-1 PF12308.8 KLO11959.1 - 3 7.9 5.2 15 5.7 0.5 3.3 3 0 0 3 3 2 0 Neurogenesis glycoprotein BNR_4 PF15892.5 KLO11961.1 - 5.5e-57 193.2 0.1 1e-56 192.3 0.1 1.4 1 1 0 1 1 1 1 BNR repeat-containing family member Peptidase_M36 PF02128.15 KLO11962.1 - 2.1e-136 455.0 0.0 3.5e-136 454.2 0.0 1.4 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KLO11962.1 - 6e-06 26.0 2.4 6.9e-06 25.8 0.5 2.1 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KLO11962.1 - 0.044 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M48_N PF16491.5 KLO11963.1 - 1.2e-62 211.0 6.3 1.2e-62 211.0 6.3 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KLO11963.1 - 6.1e-36 124.0 0.0 1.4e-35 122.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KLO11963.1 - 0.012 14.8 0.7 0.044 13.0 0.1 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 GMC_oxred_N PF00732.19 KLO11965.1 - 1.2e-61 208.7 0.1 1.8e-61 208.1 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO11965.1 - 1.4e-32 113.2 0.0 2.6e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KLO11965.1 - 2.5e-06 26.8 0.1 4.4e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KLO11965.1 - 0.00014 21.0 1.4 0.0018 17.5 1.4 2.1 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KLO11965.1 - 0.0055 16.0 0.1 0.01 15.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KLO11965.1 - 0.02 14.1 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO11965.1 - 0.076 11.7 0.2 0.13 10.9 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KLO11965.1 - 0.18 10.8 0.1 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.24 KLO11965.1 - 0.3 10.6 1.7 0.71 9.4 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Aldedh PF00171.22 KLO11966.1 - 3.1e-123 411.7 0.0 3.4e-123 411.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KLO11966.1 - 3.4e-05 23.1 0.0 5.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) BAR_2 PF10455.9 KLO11967.1 - 2.4e-51 174.6 0.2 5.3e-51 173.5 0.2 1.5 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KLO11967.1 - 1.5e-15 57.5 1.6 1.1e-14 54.7 1.6 1.9 1 1 0 1 1 1 1 BAR domain Uds1 PF15456.6 KLO11967.1 - 0.057 13.6 3.9 1.3 9.2 0.1 2.6 2 0 0 2 2 2 0 Up-regulated During Septation DPBB_1 PF03330.18 KLO11968.1 - 4.6e-09 36.4 0.4 9.4e-09 35.4 0.1 1.6 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 KLO11968.1 - 0.0019 18.1 0.2 0.0026 17.6 0.2 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 KLO11969.1 - 8.7e-09 35.5 0.0 1.7e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KLO11969.1 - 0.0082 16.0 0.1 0.01 15.7 0.1 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 KLO11970.1 - 6.9e-08 32.7 0.1 1.3e-07 31.8 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KLO11970.1 - 0.0057 16.5 0.1 0.0064 16.3 0.1 1.3 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 KLO11971.1 - 4.8e-09 36.4 0.0 8.3e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KLO11971.1 - 0.00012 21.9 0.1 0.00016 21.5 0.1 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 KLO11972.1 - 3.1e-06 27.4 0.0 7.6e-06 26.1 0.0 1.7 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 KLO11972.1 - 0.00055 19.8 0.0 0.00071 19.4 0.0 1.1 1 0 0 1 1 1 1 Barwin family Proteasome PF00227.26 KLO11973.1 - 2.9e-47 160.6 0.1 3.7e-47 160.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KLO11973.1 - 1.8e-09 36.8 0.3 1.8e-09 36.8 0.3 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NUDIX_2 PF13869.6 KLO11974.1 - 1.5e-83 279.0 0.0 1.7e-83 278.8 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF3808 PF10300.9 KLO11975.1 - 2.2e-84 283.9 0.0 3e-84 283.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 KLO11975.1 - 1.8e-07 30.7 0.7 0.044 13.9 0.1 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KLO11975.1 - 2.7e-07 30.8 0.2 0.044 14.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KLO11975.1 - 9.6e-05 22.9 4.7 1.6 9.7 0.2 4.3 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KLO11975.1 - 0.0001 22.2 0.1 0.028 14.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KLO11975.1 - 0.00027 20.8 0.7 0.34 11.0 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KLO11975.1 - 0.00055 19.6 0.0 0.44 10.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO11975.1 - 0.01 16.1 3.8 0.19 12.0 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KLO11975.1 - 0.027 14.4 2.6 0.11 12.4 0.3 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KLO11975.1 - 0.03 15.0 4.1 2.1 9.2 0.0 4.9 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KLO11975.1 - 0.072 13.8 7.6 2.7 8.7 0.2 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF3606 PF12244.8 KLO11975.1 - 0.08 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) DPBB_1 PF03330.18 KLO11976.1 - 2.5e-09 37.3 0.1 5.4e-09 36.2 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KLO11976.1 - 0.0019 18.0 0.3 0.0029 17.5 0.2 1.3 1 1 0 1 1 1 1 Barwin family Sulfate_transp PF00916.20 KLO11977.1 - 2.7e-54 184.4 19.4 2.7e-54 184.4 19.4 2.1 2 0 0 2 2 2 1 Sulfate permease family cNMP_binding PF00027.29 KLO11977.1 - 2.6e-12 46.6 0.0 5.3e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KLO11977.1 - 7.2e-10 38.5 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KLO11977.1 - 0.0051 17.2 3.9 0.0051 17.2 3.9 3.6 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 KLO11977.1 - 0.0081 16.5 0.4 0.059 13.7 0.1 2.4 2 0 0 2 2 2 1 STAS domain RhoGEF PF00621.20 KLO11978.1 - 6.5e-14 52.6 0.0 1e-13 51.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain SR-25 PF10500.9 KLO11978.1 - 1.1 8.8 6.6 1.8 8.1 6.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein dCache_2 PF08269.11 KLO11979.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Cache domain Hydrophobin PF01185.18 KLO11980.1 - 6e-14 52.4 11.4 7.3e-14 52.2 11.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin dsrm PF00035.26 KLO11981.1 - 0.16 12.7 0.1 1.2 9.9 0.1 2.6 2 0 0 2 2 2 0 Double-stranded RNA binding motif Ras PF00071.22 KLO11982.1 - 5.3e-55 185.4 0.1 6.3e-55 185.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO11982.1 - 6.8e-33 113.4 0.1 1e-32 112.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO11982.1 - 2.7e-17 62.8 0.1 3.4e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KLO11982.1 - 7.3e-08 32.0 0.0 9.9e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KLO11982.1 - 1.1e-06 28.8 0.0 2.7e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KLO11982.1 - 1.5e-05 24.7 0.1 2.6e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KLO11982.1 - 0.0027 16.9 1.2 0.39 9.8 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 KLO11982.1 - 0.0075 16.7 0.0 0.022 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 KLO11982.1 - 0.018 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 KLO11982.1 - 0.02 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KLO11982.1 - 0.028 14.3 0.0 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KLO11982.1 - 0.031 14.0 0.0 0.1 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KLO11982.1 - 0.098 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF2119 PF09892.9 KLO11982.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) Dynamin_N PF00350.23 KLO11982.1 - 0.11 12.5 0.0 0.44 10.6 0.0 1.9 2 1 0 2 2 2 0 Dynamin family Arm_3 PF16186.5 KLO11983.1 - 3.5e-20 71.3 1.9 2.1e-18 65.6 0.3 2.4 2 0 0 2 2 2 2 Atypical Arm repeat Arm PF00514.23 KLO11983.1 - 1.9e-14 53.1 11.9 9.9e-06 25.4 2.2 5.6 4 1 0 4 4 4 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KLO11983.1 - 0.0055 17.2 0.7 0.039 14.5 0.1 2.7 2 1 1 3 3 3 1 HEAT-like repeat HEAT PF02985.22 KLO11983.1 - 0.009 16.2 0.1 2 8.9 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.6 KLO11983.1 - 0.015 15.7 0.1 0.029 14.7 0.1 1.5 1 0 0 1 1 1 0 HEAT repeats Ribosomal_S21 PF01165.20 KLO11984.1 - 0.25 11.1 4.4 1.1 9.0 0.8 2.5 2 0 0 2 2 2 0 Ribosomal protein S21 Spt5-NGN PF03439.13 KLO11985.1 - 2.2e-08 33.9 0.0 5e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KLO11985.1 - 0.091 13.7 1.3 0.25 12.4 1.3 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal JmjC PF02373.22 KLO11986.1 - 0.14 12.6 0.0 0.86 10.0 0.0 2.4 2 0 0 2 2 2 0 JmjC domain, hydroxylase Pkinase PF00069.25 KLO11987.1 - 0.00025 20.5 0.0 0.00027 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 KLO11987.1 - 0.0013 18.4 0.0 0.0014 18.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KLO11987.1 - 0.0035 17.0 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family DUF881 PF05949.12 KLO11987.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) CHAD PF05235.14 KLO11988.1 - 0.04 13.9 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 CHAD domain Fungal_trans PF04082.18 KLO11989.1 - 3.6e-14 52.4 0.3 6.5e-14 51.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO11989.1 - 2.2e-05 24.5 10.3 3.7e-05 23.8 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HNF-1A_C PF04813.12 KLO11989.1 - 0.066 14.0 1.8 0.24 12.2 1.4 2.2 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Gag_p17 PF00540.18 KLO11989.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) MCM_bind PF09739.9 KLO11990.1 - 3.1e-70 237.3 0.0 9e-62 209.3 0.1 2.2 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor PGM_PMM_I PF02878.16 KLO11991.1 - 5.4e-39 133.0 0.0 9.8e-39 132.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KLO11991.1 - 7.3e-20 71.3 0.0 1.3e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KLO11991.1 - 3.5e-18 66.1 0.0 9.5e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KLO11991.1 - 5.4e-05 23.3 0.0 0.00016 21.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PHD PF00628.29 KLO11992.1 - 8.3e-16 57.6 16.3 2e-10 40.4 4.4 2.9 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 KLO11992.1 - 0.00045 19.9 0.6 0.027 14.1 0.2 2.4 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 KLO11992.1 - 0.0049 17.1 4.0 0.0083 16.4 1.5 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain C1_1 PF00130.22 KLO11992.1 - 0.037 13.9 0.5 0.037 13.9 0.5 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HscB_4_cys PF18256.1 KLO11992.1 - 0.053 13.4 0.1 0.053 13.4 0.1 2.8 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif PHD_2 PF13831.6 KLO11992.1 - 0.07 12.7 0.2 0.07 12.7 0.2 3.5 4 1 0 4 4 4 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KLO11992.1 - 0.11 12.7 0.3 0.11 12.7 0.3 1.8 2 0 0 2 2 2 0 PHD-zinc-finger like domain PHD_4 PF16866.5 KLO11992.1 - 1.8 8.7 13.2 0.77 9.9 2.0 2.7 2 0 0 2 2 2 0 PHD-finger DUF202 PF02656.15 KLO11993.1 - 0.00011 22.5 0.2 0.0008 19.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Saf_2TM PF18303.1 KLO11993.1 - 0.018 14.6 0.5 0.7 9.5 0.0 2.0 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain TPPK_C PF12555.8 KLO11993.1 - 0.11 12.5 3.6 0.43 10.7 0.5 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal YbgT_YccB PF08173.11 KLO11993.1 - 6.6 6.9 8.0 0.28 11.3 1.4 2.1 2 0 0 2 2 2 0 Membrane bound YbgT-like protein PhoD PF09423.10 KLO11994.1 - 6.7e-36 124.0 2.4 2.5e-35 122.1 2.4 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase Metallophos PF00149.28 KLO11994.1 - 0.00041 20.9 1.1 0.0031 18.1 1.9 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Myosin_head PF00063.21 KLO11995.1 - 3e-259 861.9 0.4 6.2e-259 860.8 0.0 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 KLO11995.1 - 9e-28 96.6 2.2 9e-28 96.6 2.2 3.3 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 KLO11995.1 - 5e-12 44.5 41.7 0.0014 18.2 3.1 6.9 6 0 0 6 6 6 6 IQ calmodulin-binding motif AAA_22 PF13401.6 KLO11995.1 - 0.00044 20.5 0.0 0.0023 18.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain TPR_MLP1_2 PF07926.12 KLO11995.1 - 0.0055 16.8 7.1 0.0055 16.8 7.1 2.7 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Myosin_N PF02736.19 KLO11995.1 - 0.012 15.4 2.7 0.027 14.3 2.7 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain DUF4115 PF13464.6 KLO11995.1 - 0.068 13.4 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) DUF2645 PF10840.8 KLO11995.1 - 0.068 13.8 0.1 0.29 11.8 0.0 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF2645) HOOK PF05622.12 KLO11995.1 - 0.076 11.2 23.7 0.12 10.5 23.7 1.1 1 0 0 1 1 1 0 HOOK protein AAA_16 PF13191.6 KLO11995.1 - 0.1 13.0 0.0 0.1 13.0 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain DUF1818 PF08848.11 KLO11995.1 - 0.21 11.7 1.7 0.42 10.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) ABC_tran PF00005.27 KLO11995.1 - 1.2 9.7 5.5 1.1 9.8 0.1 2.6 2 0 0 2 2 2 0 ABC transporter COG4 PF08318.12 KLO11996.1 - 1.3e-82 277.6 0.0 2.4e-82 276.7 0.0 1.5 1 0 0 1 1 1 1 COG4 transport protein DUF445 PF04286.12 KLO11996.1 - 0.029 14.2 0.2 0.052 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Phasin PF05597.11 KLO11996.1 - 0.11 12.5 0.4 0.51 10.4 0.0 2.3 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Snf7 PF03357.21 KLO11997.1 - 1.4e-36 125.7 24.0 9.1e-36 123.0 22.7 2.0 2 0 0 2 2 2 1 Snf7 YlqD PF11068.8 KLO11997.1 - 0.19 12.1 14.1 0.23 11.8 8.7 2.2 1 1 1 2 2 2 0 YlqD protein DUF1002 PF06207.11 KLO11997.1 - 1 8.8 7.0 0.23 10.9 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) Cas6b_C PF17262.2 KLO11997.1 - 1.8 8.7 4.8 8.1 6.6 0.7 2.3 1 1 1 2 2 2 0 Cas6b C-terminal domain Glyco_hydro_3_C PF01915.22 KLO11998.1 - 1.7e-64 217.5 0.0 3.2e-64 216.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KLO11998.1 - 2.8e-39 135.4 0.0 4.8e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KLO11998.1 - 5e-19 68.2 0.0 9.3e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KLO11998.1 - 1.1e-06 28.5 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Peptidase_M6 PF05547.11 KLO11998.1 - 0.21 9.9 0.0 0.31 9.3 0.0 1.1 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 PIG-S PF10510.9 KLO11998.1 - 0.23 10.3 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF2340 PF10209.9 KLO11999.1 - 1.7e-44 151.1 1.5 2e-44 150.9 1.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Blt1 PF12754.7 KLO11999.1 - 0.006 16.9 0.4 0.0077 16.6 0.4 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Pkinase PF00069.25 KLO12000.1 - 2e-54 184.7 0.0 2.8e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12000.1 - 2.4e-19 69.7 0.2 5.2e-19 68.5 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KLO12000.1 - 0.0052 16.7 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO12000.1 - 0.015 14.9 0.2 0.03 13.9 0.2 1.5 1 0 0 1 1 1 0 RIO1 family ABC1 PF03109.16 KLO12000.1 - 0.036 14.2 0.2 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 ABC1 family DUF1053 PF06327.14 KLO12000.1 - 0.14 12.7 0.0 0.68 10.5 0.0 2.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) DUF974 PF06159.13 KLO12001.1 - 1.5e-75 254.2 0.0 2.2e-75 253.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF974) V-ATPase_H_N PF03224.14 KLO12002.1 - 1.9e-90 303.4 2.7 1.9e-90 303.4 2.7 1.3 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KLO12002.1 - 2e-42 144.0 0.1 1.4e-41 141.2 0.0 2.3 2 0 0 2 2 2 1 V-ATPase subunit H Arm_2 PF04826.13 KLO12002.1 - 0.00058 19.4 0.0 0.0019 17.7 0.0 1.8 1 0 0 1 1 1 1 Armadillo-like RTP1_C1 PF10363.9 KLO12002.1 - 0.014 15.5 0.3 0.13 12.5 0.0 2.7 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KLO12002.1 - 0.023 14.9 0.3 1.1 9.7 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 KLO12002.1 - 0.1 13.0 1.0 1.6 9.2 0.0 3.2 4 2 0 4 4 4 0 HEAT repeats Arm PF00514.23 KLO12002.1 - 0.16 12.1 1.2 14 5.9 0.0 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat MRP-L46 PF11788.8 KLO12003.1 - 3.7e-19 69.6 1.2 8.5e-19 68.5 1.2 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KLO12003.1 - 5.1e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Endonuclease_NS PF01223.23 KLO12004.1 - 6.4e-57 193.0 0.0 8e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease R3H PF01424.22 KLO12005.1 - 2.3e-11 43.5 0.1 5.1e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KLO12005.1 - 1.7e-07 31.0 0.0 6.9e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.26 KLO12009.1 - 2.4e-44 150.4 0.0 2.9e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KLO12009.1 - 4.8e-05 23.6 0.0 5.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KLO12009.1 - 0.0033 17.3 0.0 0.0059 16.5 0.0 1.5 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 KLO12009.1 - 0.0043 16.8 0.0 0.0056 16.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B EF-hand_4 PF12763.7 KLO12010.1 - 1.9e-32 111.3 0.0 5.4e-13 48.8 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 KLO12010.1 - 3.2e-07 30.1 0.0 7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.6 KLO12010.1 - 2.2e-06 28.0 0.0 0.013 15.9 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KLO12010.1 - 0.00041 20.1 3.5 5.6 7.2 0.1 4.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 KLO12010.1 - 0.00073 18.9 0.6 5.6 6.8 0.0 4.3 4 0 0 4 4 4 1 EF hand WEMBL PF05701.11 KLO12010.1 - 0.004 15.9 27.8 0.0063 15.3 27.8 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light MMPL PF03176.15 KLO12010.1 - 0.16 10.9 4.0 0.32 9.9 4.0 1.5 1 0 0 1 1 1 0 MMPL family TPR_MLP1_2 PF07926.12 KLO12010.1 - 4 7.5 41.5 2.9 8.0 15.1 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 KLO12010.1 - 5.7 6.4 38.1 0.14 11.7 16.5 2.6 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain FH2 PF02181.23 KLO12010.1 - 6.8 5.7 16.6 6.4 5.8 1.7 2.2 2 0 0 2 2 2 0 Formin Homology 2 Domain ADIP PF11559.8 KLO12010.1 - 7.8 6.6 33.3 0.34 11.0 11.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 KLO12010.1 - 8.9 5.3 31.1 5.6 5.9 17.1 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PDEase_II PF02112.15 KLO12011.1 - 5.4e-38 130.9 0.0 9e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KLO12011.1 - 5e-06 26.2 0.0 1e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KLO12011.1 - 0.0036 17.3 0.1 0.0065 16.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily NAPRTase PF04095.16 KLO12012.1 - 1.3e-61 208.3 0.0 1.6e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KLO12012.1 - 4.2e-34 117.6 0.0 6.5e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain BIR PF00653.21 KLO12013.1 - 4.6e-39 132.9 1.8 1e-20 74.2 0.3 2.1 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 KLO12013.1 - 0.0076 16.3 0.0 4.5 7.3 0.0 2.7 2 1 0 3 3 3 2 C3HC zinc finger-like DZR PF12773.7 KLO12013.1 - 0.14 12.2 2.6 2 8.5 0.8 2.3 2 0 0 2 2 2 0 Double zinc ribbon Striatin PF08232.12 KLO12014.1 - 9e-47 159.5 0.9 9e-47 159.5 0.9 3.7 3 1 0 3 3 3 1 Striatin family WD40 PF00400.32 KLO12014.1 - 1.4e-36 123.9 5.4 7.3e-06 26.6 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO12014.1 - 1.1e-07 32.0 0.4 0.1 12.9 0.0 5.0 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 KLO12014.1 - 0.0027 17.8 22.3 0.014 15.4 7.3 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Nucleoporin_N PF08801.11 KLO12014.1 - 0.0032 16.3 0.0 0.34 9.6 0.0 2.6 2 1 0 2 2 2 1 Nup133 N terminal like Nup160 PF11715.8 KLO12014.1 - 0.012 14.3 0.1 0.092 11.4 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KLO12014.1 - 0.058 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 PQQ-like domain Nucleo_P87 PF07267.11 KLO12014.1 - 1.1 8.1 8.0 1.8 7.3 8.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MPP6 PF10175.9 KLO12014.1 - 2.9 8.4 6.7 8.5 6.9 6.7 1.7 1 0 0 1 1 1 0 M-phase phosphoprotein 6 TMA7 PF09072.10 KLO12015.1 - 1.6e-21 76.9 19.9 2.2e-21 76.4 19.9 1.2 1 0 0 1 1 1 1 Translation machinery associated TMA7 Peptidase_S9 PF00326.21 KLO12016.1 - 9.6e-14 51.4 0.0 1.6e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KLO12016.1 - 4.4e-06 26.1 0.1 0.0085 15.4 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KLO12016.1 - 1.2e-05 25.1 0.1 2.7e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KLO12016.1 - 0.0048 16.6 0.4 0.012 15.3 0.1 1.7 2 0 0 2 2 2 1 Putative esterase DLH PF01738.18 KLO12016.1 - 0.024 14.2 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.11 KLO12016.1 - 0.075 12.9 0.1 0.53 10.2 0.0 2.3 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1749 PF08538.10 KLO12016.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Tannase PF07519.11 KLO12016.1 - 0.25 10.2 0.0 0.41 9.5 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase Mob1_phocein PF03637.17 KLO12017.1 - 1e-68 230.7 0.3 1.3e-68 230.3 0.3 1.1 1 0 0 1 1 1 1 Mob1/phocein family SDA1 PF05285.12 KLO12018.1 - 3.4e-81 273.4 46.9 2.5e-46 158.7 6.9 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 KLO12018.1 - 1.4e-17 63.7 0.7 4.1e-17 62.2 0.1 2.1 2 0 0 2 2 2 1 NUC130/3NT domain DUF4158 PF13700.6 KLO12018.1 - 0.11 12.4 0.1 13 5.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) HOOK PF05622.12 KLO12019.1 - 4.3e-64 216.9 75.8 2.3e-63 214.5 47.9 2.2 1 1 1 2 2 2 2 HOOK protein BLOC1_2 PF10046.9 KLO12019.1 - 0.0073 16.6 9.2 0.0073 16.6 9.2 7.5 5 3 2 8 8 8 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 HMMR_N PF15905.5 KLO12019.1 - 0.0078 15.7 23.7 0.0078 15.7 23.7 5.5 2 2 2 4 4 4 1 Hyaluronan mediated motility receptor N-terminal DUF5631 PF18645.1 KLO12019.1 - 0.096 13.1 1.9 7.8 7.0 0.0 4.5 4 1 0 4 4 4 0 Family of unknown function (DUF5631) Pih1_fungal_CS PF18482.1 KLO12019.1 - 0.14 12.7 2.4 0.3 11.6 0.2 2.8 2 0 0 2 2 2 0 Fungal Pih1 CS domain Imm7 PF15585.6 KLO12019.1 - 0.25 11.6 3.6 0.3 11.4 0.3 2.9 2 0 0 2 2 2 0 Immunity protein 7 DUF3618 PF12277.8 KLO12019.1 - 0.41 10.9 15.8 7.8 6.8 1.1 5.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3618) Not1 PF04054.15 KLO12020.1 - 5.4e-129 430.3 0.1 1.3e-128 429.1 0.1 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KLO12020.1 - 1.9e-96 321.8 1.3 2e-94 315.2 0.1 2.5 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 KLO12020.1 - 3.5e-54 182.9 0.0 6.8e-54 181.9 0.0 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 KLO12020.1 - 7.1e-49 165.5 0.0 1.7e-48 164.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 KLO12020.1 - 8e-47 159.1 0.7 2e-46 157.8 0.7 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat FdhE PF04216.12 KLO12020.1 - 0.047 13.6 0.4 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Alpha-amylase PF00128.24 KLO12021.1 - 9.3e-48 163.5 0.0 9.5e-47 160.2 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KLO12021.1 - 8.1e-13 48.5 0.2 2e-12 47.2 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Sugar_tr PF00083.24 KLO12022.1 - 2.6e-71 240.8 20.2 3.7e-71 240.3 20.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO12022.1 - 2.2e-20 72.9 36.5 2.2e-20 72.9 36.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KLO12022.1 - 4.2e-07 28.9 23.6 0.001 17.7 0.4 3.7 3 1 1 4 4 4 2 MFS/sugar transport protein PKI PF02827.16 KLO12023.1 - 0.1 12.8 0.9 0.1 12.8 0.9 3.4 3 1 1 4 4 4 0 cAMP-dependent protein kinase inhibitor Atg14 PF10186.9 KLO12023.1 - 1.9 7.5 13.1 3.2 6.8 13.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KLO12023.1 - 3 7.9 10.1 4.1 7.5 10.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5542 PF17696.1 KLO12023.1 - 5 7.3 7.2 0.83 9.8 0.2 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5542) Pyridoxal_deC PF00282.19 KLO12024.1 - 5.9e-65 219.4 0.0 7.6e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KLO12024.1 - 9.4e-06 24.8 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Pkinase_Tyr PF07714.17 KLO12025.1 - 9.7e-45 152.9 0.0 1.7e-44 152.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO12025.1 - 1.5e-36 126.2 0.0 3.9e-36 124.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain RasGEF PF00617.19 KLO12025.1 - 2.4e-33 115.8 0.4 4.8e-33 114.8 0.4 1.5 1 0 0 1 1 1 1 RasGEF domain Kinase-like PF14531.6 KLO12025.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO12025.1 - 0.014 15.3 1.7 0.26 11.2 0.2 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO12025.1 - 0.016 14.0 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KLO12025.1 - 0.081 12.3 0.9 0.21 10.9 0.0 2.1 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO12025.1 - 0.081 12.5 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 RIO1 family RTC PF01137.21 KLO12026.1 - 2.9e-79 265.4 0.0 3.5e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KLO12026.1 - 1.4e-21 76.9 0.0 2.5e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CDC50 PF03381.15 KLO12027.1 - 2e-90 303.1 0.1 2.5e-90 302.8 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DnaJ_C PF01556.18 KLO12028.1 - 1.1e-39 135.9 0.8 1.7e-39 135.3 0.8 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KLO12028.1 - 6.6e-24 83.8 0.9 1.4e-23 82.7 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KLO12028.1 - 6.6e-17 61.6 20.8 1.1e-16 60.9 20.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KLO12028.1 - 9.3e-07 28.7 10.3 0.0017 18.2 1.4 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 KLO12028.1 - 1.6 8.8 9.6 1.1 9.3 0.9 2.3 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 KLO12028.1 - 4.2 7.4 13.7 7.1 6.7 3.8 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CN_hydrolase PF00795.22 KLO12029.1 - 7e-57 192.7 0.0 7.9e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DAGK_cat PF00781.24 KLO12030.1 - 2.9e-15 56.0 0.1 5.2e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ADK PF00406.22 KLO12031.1 - 4.3e-42 143.8 0.2 8.9e-42 142.7 0.2 1.5 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KLO12031.1 - 3.6e-31 108.4 0.6 6.4e-31 107.6 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KLO12031.1 - 2e-10 41.3 0.0 3.3e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KLO12031.1 - 7e-05 22.6 1.8 0.0043 16.7 1.8 2.1 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 KLO12031.1 - 0.0018 18.5 0.1 0.05 13.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KLO12031.1 - 0.0027 17.6 0.7 0.03 14.2 0.5 2.0 2 0 0 2 2 2 1 Deoxynucleoside kinase HA2 PF04408.23 KLO12032.1 - 8.5e-17 61.4 0.0 2.4e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KLO12032.1 - 2.8e-15 56.6 0.0 6.9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KLO12032.1 - 1.4e-12 47.8 0.0 3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KLO12032.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Transposase_21 PF02992.14 KLO12033.1 - 1.2e-05 24.6 0.0 2.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 KLO12033.1 - 0.0069 15.9 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Plavaka PF18759.1 KLO12033.1 - 0.007 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase MEA1 PF06910.11 KLO12033.1 - 0.077 13.6 3.8 0.097 13.3 1.8 2.2 2 1 0 2 2 2 0 Male enhanced antigen 1 (MEA1) Helicase_C PF00271.31 KLO12034.1 - 5.3e-14 52.5 0.0 1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KLO12034.1 - 0.0077 16.9 0.2 0.017 15.8 0.2 1.6 1 0 0 1 1 1 1 RecQ zinc-binding p450 PF00067.22 KLO12036.1 - 2.2e-70 237.7 0.0 3.1e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KLO12037.1 - 5.6e-15 55.1 31.3 3.2e-09 36.2 10.6 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily TMEM141 PF15110.6 KLO12037.1 - 0.052 14.1 0.6 0.99 10.0 0.0 2.5 2 0 0 2 2 2 0 TMEM141 protein family DUF1279 PF06916.13 KLO12037.1 - 0.061 13.9 1.0 9 6.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) F-box-like PF12937.7 KLO12038.1 - 3.2e-07 30.1 2.1 1.1e-06 28.4 2.1 2.0 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO12038.1 - 0.003 17.9 2.2 12 6.5 0.1 4.7 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO12039.1 - 0.00032 20.5 1.9 0.0018 18.1 1.9 2.4 1 1 0 1 1 1 1 F-box-like p450 PF00067.22 KLO12040.1 - 3e-69 234.0 0.0 3.9e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 H_PPase PF03030.16 KLO12041.1 - 0.0025 16.5 1.8 0.0025 16.5 1.8 2.0 1 1 1 2 2 2 1 Inorganic H+ pyrophosphatase Aminopep PF10023.9 KLO12041.1 - 0.18 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative aminopeptidase MFS_1 PF07690.16 KLO12043.1 - 7.8e-22 77.7 56.7 9.2e-17 61.0 47.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.7 KLO12044.1 - 1.3e-09 39.0 0.2 1.8e-09 38.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family TraL PF07178.11 KLO12045.1 - 4.4 7.8 6.5 2.2 8.8 0.2 3.2 3 1 1 4 4 4 0 TraL protein p450 PF00067.22 KLO12046.1 - 1.8e-70 238.0 0.0 2.1e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VIT1 PF01988.19 KLO12053.1 - 0.65 9.8 4.4 0.77 9.6 4.4 1.2 1 0 0 1 1 1 0 VIT family AGTRAP PF06396.11 KLO12054.1 - 0.22 11.3 4.8 5.9 6.7 0.5 2.4 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) FixH PF05751.11 KLO12058.1 - 0.65 10.0 2.1 1.3 9.0 2.1 1.4 1 0 0 1 1 1 0 FixH SieB PF14163.6 KLO12059.1 - 0.12 11.8 1.0 0.28 10.7 1.0 1.6 1 0 0 1 1 1 0 Super-infection exclusion protein B NAD_binding_10 PF13460.6 KLO12062.1 - 5e-18 65.7 0.0 6.5e-11 42.5 0.0 2.1 2 0 0 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 KLO12062.1 - 1.8e-06 27.6 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO12062.1 - 1.2e-05 25.0 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KLO12062.1 - 0.00026 20.6 0.0 0.00049 19.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO12062.1 - 0.0029 17.1 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KLO12062.1 - 0.003 17.1 0.0 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 KLO12062.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 KR domain ApbA PF02558.16 KLO12062.1 - 0.035 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 KLO12063.1 - 5.7e-09 36.1 0.0 1e-06 28.8 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KLO12063.1 - 2.4e-05 23.9 0.0 4.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO12063.1 - 0.017 14.7 0.0 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 KLO12064.1 - 3.5e-07 30.1 0.0 6.2e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO12064.1 - 1.6e-06 28.1 0.0 2.1e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO12064.1 - 7.9e-06 26.5 0.0 1.4e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KLO12064.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 KLO12064.1 - 4.7e-05 24.0 0.0 8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO12064.1 - 5.1e-05 23.8 0.0 8.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain ABC2_membrane PF01061.24 KLO12065.1 - 2.3e-64 216.7 60.3 6.2e-35 120.5 21.1 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KLO12065.1 - 9.6e-34 116.8 0.0 6.2e-16 59.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KLO12065.1 - 7.4e-22 77.1 13.1 1e-18 67.0 0.4 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KLO12065.1 - 9.4e-10 39.0 0.2 2.6e-09 37.5 0.2 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 KLO12065.1 - 3e-06 27.4 0.0 0.0041 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KLO12065.1 - 1.2e-05 25.9 3.7 0.0068 17.0 0.0 3.5 4 0 0 4 4 3 2 AAA domain cobW PF02492.19 KLO12065.1 - 2.4e-05 24.0 0.0 0.22 11.1 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KLO12065.1 - 4.6e-05 23.9 0.1 0.045 14.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KLO12065.1 - 0.00016 22.0 1.4 0.43 10.9 0.1 3.2 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KLO12065.1 - 0.0011 19.2 0.0 0.61 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KLO12065.1 - 0.0014 19.0 1.8 0.21 12.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KLO12065.1 - 0.0026 17.6 0.0 0.63 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KLO12065.1 - 0.0035 17.1 0.6 0.13 12.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KLO12065.1 - 0.011 15.6 0.1 0.038 13.9 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase DUF4834 PF16118.5 KLO12065.1 - 0.013 16.4 1.4 0.048 14.6 1.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AAA_30 PF13604.6 KLO12065.1 - 0.014 15.1 0.6 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KLO12065.1 - 0.034 13.6 0.2 1.3 8.4 0.1 3.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KLO12065.1 - 0.07 12.7 0.7 0.24 10.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KLO12065.1 - 0.16 12.4 0.1 26 5.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KLO12065.1 - 0.22 11.9 1.5 4.4 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KLO12065.1 - 7.1 6.5 5.4 26 4.7 0.0 2.8 3 0 0 3 3 3 0 NACHT domain Pkinase PF00069.25 KLO12067.1 - 7.7e-71 238.5 0.0 1.4e-70 237.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12067.1 - 1.2e-51 175.5 0.0 1.9e-51 174.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO12067.1 - 8.4e-06 24.8 0.0 4.4e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KLO12067.1 - 8.8e-05 22.0 0.0 0.016 14.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like DUF1241 PF06840.11 KLO12067.1 - 0.0012 18.6 0.1 0.0023 17.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Haspin_kinase PF12330.8 KLO12067.1 - 0.031 13.2 0.0 5.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain SOG2 PF10428.9 KLO12067.1 - 0.43 9.7 5.0 0.62 9.2 5.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4726 PF15855.5 KLO12067.1 - 0.5 10.6 3.9 1.2 9.4 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) SCIMP PF15050.6 KLO12067.1 - 4.2 7.8 8.2 11 6.4 0.6 3.3 2 1 1 3 3 3 0 SCIMP protein Ribosomal_L1 PF00687.21 KLO12068.1 - 6.9e-25 88.0 0.1 1.2e-24 87.2 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-C2H2_4 PF13894.6 KLO12069.1 - 0.078 13.9 8.0 2 9.5 0.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO12069.1 - 0.15 12.6 5.7 6.3 7.5 0.9 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type CPT_N PF16484.5 KLO12070.1 - 0.15 12.1 0.1 0.33 11.0 0.1 1.6 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus F-box-like PF12937.7 KLO12070.1 - 0.3 11.0 0.0 0.3 11.0 0.0 3.3 4 1 0 4 4 4 0 F-box-like FHA PF00498.26 KLO12075.1 - 4e-10 39.9 0.0 1.1e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 FHA domain SAC3_GANP PF03399.16 KLO12076.1 - 8.1e-58 196.1 0.0 1.3e-57 195.4 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family 2OG-FeII_Oxy_3 PF13640.6 KLO12078.1 - 7.3e-11 42.8 0.0 2.8e-10 41.0 0.1 2.0 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KLO12078.1 - 0.046 14.4 0.0 0.098 13.3 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4279 PF14106.6 KLO12078.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) Git3 PF11710.8 KLO12079.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Fur_reg_FbpB PF13040.6 KLO12085.1 - 0.22 11.1 2.9 0.45 10.1 2.9 1.5 1 0 0 1 1 1 0 Fur-regulated basic protein B DUF3006 PF11213.8 KLO12085.1 - 0.3 11.3 2.5 0.55 10.5 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) DUF2719 PF10891.8 KLO12086.1 - 0.11 12.4 2.0 0.27 11.2 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) FYVE PF01363.21 KLO12086.1 - 0.65 10.2 13.8 1.1 9.5 0.5 2.6 2 1 0 2 2 2 0 FYVE zinc finger FYVE_2 PF02318.16 KLO12086.1 - 3.6 7.8 16.4 3.8 7.7 4.5 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger PIN_4 PF13638.6 KLO12088.1 - 3.1e-08 34.0 0.0 4.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 PIN domain ENTH PF01417.20 KLO12089.1 - 2.4e-50 169.8 0.2 4.1e-50 169.0 0.2 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KLO12089.1 - 0.00076 18.6 0.0 0.00076 18.6 0.0 2.2 2 0 0 2 2 2 1 ANTH domain Peptidase_C12 PF01088.21 KLO12090.1 - 3.3e-53 180.6 0.0 5.7e-53 179.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KLO12090.1 - 2.9e-12 46.3 0.2 7.4e-12 45.0 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases AAT PF03417.16 KLO12093.1 - 4.3e-12 46.2 0.0 3.5e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase RNase_PH PF01138.21 KLO12094.1 - 6.5e-19 68.7 0.0 9.7e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_M24 PF00557.24 KLO12095.1 - 1.7e-56 191.3 0.0 2.2e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KLO12095.1 - 2.1e-19 69.4 0.0 3.6e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF1639 PF07797.14 KLO12096.1 - 0.005 16.8 0.6 1.8 8.6 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1639) DUF2347 PF09804.9 KLO12097.1 - 4.7e-44 151.1 0.0 1.7e-43 149.3 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KLO12097.1 - 0.001 19.0 0.0 0.0024 17.8 0.0 1.6 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.9 KLO12097.1 - 0.0021 16.8 0.0 9.2 4.8 0.0 3.2 3 0 0 3 3 3 3 Transport protein Avl9 DUF4484 PF14831.6 KLO12097.1 - 0.67 10.0 3.3 0.75 9.8 0.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4484) Cellulase PF00150.18 KLO12098.1 - 8.4e-29 100.9 5.1 1.3e-28 100.3 5.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 KLO12099.1 - 1.4e-30 106.7 0.6 2.2e-30 106.0 0.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ARD PF03079.14 KLO12100.1 - 7.1e-46 156.2 0.0 8.3e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KLO12100.1 - 1.4e-09 37.5 0.1 2.7e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KLO12100.1 - 2.5e-07 30.7 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KLO12100.1 - 0.00029 20.5 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KLO12100.1 - 0.0052 16.4 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_8 PF13621.6 KLO12100.1 - 0.024 14.3 0.0 0.047 13.4 0.0 1.4 1 1 0 1 1 1 0 Cupin-like domain Cupin_6 PF12852.7 KLO12100.1 - 0.063 13.0 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Cupin SKG6 PF08693.10 KLO12101.1 - 8.8e-09 34.6 1.7 1.9e-08 33.6 1.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KLO12101.1 - 0.0058 16.4 0.0 0.0086 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Asp PF00026.23 KLO12104.1 - 1.8e-19 70.3 0.1 1.5e-12 47.6 0.0 2.8 1 1 1 2 2 2 2 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 KLO12104.1 - 0.00011 22.7 1.1 0.33 11.5 0.0 4.4 4 1 1 5 5 5 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KLO12104.1 - 0.00057 20.5 5.0 0.021 15.5 0.0 4.6 5 1 1 6 6 6 1 Aspartyl protease TAXi_N PF14543.6 KLO12104.1 - 0.0011 19.3 0.6 0.47 10.7 0.0 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal ALMS_repeat PF18727.1 KLO12104.1 - 0.27 11.2 1.0 3.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Alstrom syndrome repeat CRISPR_Cse2 PF09485.10 KLO12105.1 - 0.14 12.7 0.0 0.2 12.2 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Pepdidase_M14_N PF18027.1 KLO12106.1 - 0.086 13.2 0.1 0.097 13.0 0.1 1.3 1 1 0 1 1 1 0 Cytosolic carboxypeptidase N-terminal domain MAGE PF01454.19 KLO12107.1 - 2.6e-51 174.4 1.0 2.6e-51 174.4 0.0 1.5 2 0 0 2 2 2 1 MAGE family FAM167 PF11652.8 KLO12107.1 - 0.16 12.4 1.1 33 5.1 0.0 3.3 3 1 1 4 4 4 0 FAM167 SEP PF08059.13 KLO12108.1 - 4.5e-23 81.6 0.0 1e-22 80.5 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KLO12108.1 - 3.2e-13 49.7 0.2 5.8e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 UBX domain DUF2381 PF09544.10 KLO12108.1 - 0.026 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) PI-PLC-X PF00388.19 KLO12109.1 - 2.3e-42 144.0 0.0 3.5e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KLO12109.1 - 1.1e-30 106.3 0.0 1.7e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain POTRA_TamA_1 PF17243.2 KLO12109.1 - 0.019 15.1 0.0 0.077 13.1 0.0 2.0 2 0 0 2 2 2 0 POTRA domain TamA domain 1 Ion_trans PF00520.31 KLO12110.1 - 6.3e-108 359.6 88.7 2.2e-31 109.0 22.7 6.1 5 1 1 6 6 6 6 Ion transport protein PCI PF01399.27 KLO12111.1 - 1e-05 26.0 0.8 0.0034 17.9 0.0 3.0 3 0 0 3 3 3 2 PCI domain SieB PF14163.6 KLO12111.1 - 2.6 7.5 4.0 8.4 5.9 4.0 1.9 1 0 0 1 1 1 0 Super-infection exclusion protein B HA2 PF04408.23 KLO12112.1 - 3.6e-25 88.3 0.1 6.9e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KLO12112.1 - 4.1e-16 59.1 0.0 1.1e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KLO12112.1 - 8.2e-11 42.2 0.0 1.6e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO12112.1 - 0.003 17.3 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase tRNA-synt_1 PF00133.22 KLO12113.1 - 2.6e-212 706.3 0.0 2.8e-211 702.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KLO12113.1 - 2.6e-35 121.6 0.1 2.6e-35 121.6 0.1 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KLO12113.1 - 1.3e-13 50.5 0.0 1.5e-06 27.2 0.0 4.1 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KLO12113.1 - 1.8e-10 40.7 0.0 5.9e-07 29.2 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 KLO12113.1 - 7e-05 23.0 1.8 7e-05 23.0 1.8 2.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 KLO12113.1 - 0.016 14.5 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Peptidase_M48 PF01435.18 KLO12114.1 - 4.2e-28 98.5 0.0 1e-27 97.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M48 Septin PF00735.18 KLO12115.1 - 1.7e-112 375.3 0.5 2.4e-112 374.8 0.5 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KLO12115.1 - 8.2e-08 32.3 0.0 2.2e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO12115.1 - 1.3e-07 31.7 0.1 1.6e-06 28.1 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KLO12115.1 - 1.7e-06 27.7 1.1 0.00014 21.5 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KLO12115.1 - 0.00019 21.7 0.1 0.00041 20.6 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 KLO12115.1 - 0.00026 20.8 0.2 0.054 13.2 0.2 2.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KLO12115.1 - 0.00027 21.4 0.1 0.0019 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KLO12115.1 - 0.0017 18.9 0.2 0.006 17.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.16 KLO12115.1 - 0.0021 17.4 0.0 0.0046 16.3 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 KLO12115.1 - 0.0029 17.9 1.3 0.0095 16.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KLO12115.1 - 0.0082 15.7 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Ras PF00071.22 KLO12115.1 - 0.0082 15.7 0.0 0.023 14.3 0.0 1.8 1 0 0 1 1 1 1 Ras family NB-ARC PF00931.22 KLO12115.1 - 0.019 14.2 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Val_tRNA-synt_C PF10458.9 KLO12115.1 - 0.02 15.1 0.9 0.02 15.1 0.9 3.1 3 1 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Sigma54_activat PF00158.26 KLO12115.1 - 0.038 13.7 0.1 0.071 12.8 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.23 KLO12115.1 - 0.048 13.7 6.4 1.1 9.3 0.0 3.1 2 1 1 3 3 3 0 Dynamin family FeoB_N PF02421.18 KLO12115.1 - 0.062 12.8 0.1 0.18 11.3 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B CLP1_P PF16575.5 KLO12115.1 - 0.063 13.1 0.1 0.25 11.1 0.1 1.9 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NACHT PF05729.12 KLO12115.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KLO12115.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KLO12115.1 - 0.14 11.8 0.2 0.14 11.8 0.2 1.9 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KLO12115.1 - 0.17 11.9 0.8 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain DivIC PF04977.15 KLO12115.1 - 0.19 11.5 2.6 0.21 11.4 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator FUSC PF04632.12 KLO12115.1 - 0.3 9.6 1.5 0.44 9.0 1.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FtsK_SpoIIIE PF01580.18 KLO12115.1 - 0.3 10.4 1.8 0.77 9.1 0.2 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family FOXP-CC PF16159.5 KLO12115.1 - 0.35 11.5 2.5 0.32 11.7 0.3 2.1 2 0 0 2 2 1 0 FOXP coiled-coil domain APG6_N PF17675.1 KLO12115.1 - 2.6 8.6 16.0 0.14 12.7 9.2 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region GTP_EFTU PF00009.27 KLO12116.1 - 2.2e-59 200.3 0.0 3.5e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KLO12116.1 - 9.6e-38 128.7 0.1 4.5e-37 126.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 KLO12116.1 - 1e-30 105.6 0.0 2.2e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KLO12116.1 - 1.8e-22 79.2 0.0 5e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KLO12116.1 - 3.6e-12 46.5 0.0 1.4e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KLO12116.1 - 1.7e-06 27.9 0.0 3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SFTA2 PF15210.6 KLO12116.1 - 0.069 13.1 0.0 9.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Surfactant-associated protein 2 NlpE_C PF17185.4 KLO12116.1 - 0.29 11.4 1.8 1.1 9.6 0.0 2.6 3 0 0 3 3 3 0 NlpE C-terminal OB domain DUF3337 PF11816.8 KLO12117.1 - 2.1e-43 148.2 0.0 2.5e-26 92.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.32 KLO12117.1 - 1.5e-22 79.4 14.6 3.6e-08 33.9 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat RAWUL PF16207.5 KLO12117.1 - 0.037 14.7 0.0 0.072 13.8 0.0 1.4 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like DUF308 PF03729.13 KLO12118.1 - 0.11 12.8 1.3 0.21 11.9 1.3 1.4 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) CAP59_mtransfer PF11735.8 KLO12119.1 - 5e-38 131.1 0.0 8.3e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 WD40 PF00400.32 KLO12120.1 - 6.7e-20 71.1 19.2 0.0001 23.0 0.5 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KLO12120.1 - 2.3e-07 30.1 0.1 0.39 9.6 0.0 3.5 2 2 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KLO12120.1 - 1.6e-06 28.3 4.7 0.069 13.5 0.1 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain AMP-binding PF00501.28 KLO12121.1 - 7.6e-51 173.0 0.0 1.1e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Calcipressin PF04847.12 KLO12122.1 - 0.048 13.4 3.1 0.055 13.2 3.1 1.3 1 1 0 1 1 1 0 Calcipressin KDZ PF18758.1 KLO12124.1 - 9.7e-46 156.2 1.2 1.6e-45 155.4 1.2 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO12124.1 - 4.4e-28 97.6 0.3 1.3e-27 96.1 0.0 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO12124.1 - 1.8e-05 24.8 0.0 5.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases DUF1116 PF06545.11 KLO12125.1 - 0.026 14.0 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) Spt5-NGN PF03439.13 KLO12127.1 - 2.3e-09 37.0 0.0 7.8e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KLO12127.1 - 9.2e-09 35.0 16.3 0.0013 18.6 0.0 5.9 6 0 0 6 6 6 2 KOW motif HMG_box_2 PF09011.10 KLO12127.1 - 0.0023 18.5 0.0 0.0078 16.8 0.0 1.9 1 0 0 1 1 1 1 HMG-box domain DUF3912 PF13051.6 KLO12127.1 - 0.021 15.1 0.0 0.065 13.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) HMG_box PF00505.19 KLO12127.1 - 0.076 13.4 0.2 0.23 11.9 0.2 1.8 1 1 0 1 1 1 0 HMG (high mobility group) box FAM76 PF16046.5 KLO12128.1 - 0.018 14.4 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 FAM76 protein Paramyxo_P PF01806.17 KLO12130.1 - 0.04 13.4 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region Pro-kuma_activ PF09286.11 KLO12132.1 - 1.2e-31 109.9 0.0 1e-30 106.9 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain DUF5450 PF17529.2 KLO12132.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5450) PNPase PF03726.14 KLO12134.1 - 0.076 13.5 4.2 0.12 12.8 4.2 1.4 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain F-box-like PF12937.7 KLO12143.1 - 0.063 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 F-box-like Med9 PF07544.13 KLO12150.1 - 0.49 10.5 2.6 0.98 9.6 1.4 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 OMP_b-brl PF13505.6 KLO12152.1 - 0.11 12.6 0.9 12 6.0 0.1 3.4 2 1 0 3 3 3 0 Outer membrane protein beta-barrel domain C6 PF01681.17 KLO12153.1 - 0.076 13.5 3.8 4.4 7.9 0.3 3.0 3 0 0 3 3 3 0 C6 domain Velvet PF11754.8 KLO12155.1 - 9.9e-41 140.3 0.2 6.2e-40 137.7 0.0 2.3 2 1 0 2 2 2 1 Velvet factor VWA_2 PF13519.6 KLO12156.1 - 0.0044 17.7 0.0 0.011 16.4 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF1667 PF07892.11 KLO12158.1 - 0.048 13.7 0.3 9.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1667) DUF4646 PF15496.6 KLO12159.1 - 7.4e-18 65.4 1.2 2.8e-17 63.5 0.4 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4646) Neisseria_TspB PF05616.13 KLO12159.1 - 1.4 7.4 4.7 2 6.8 4.7 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein TPR_2 PF07719.17 KLO12160.1 - 1.3e-08 34.3 6.0 0.069 13.3 1.3 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KLO12160.1 - 6.7e-08 32.0 5.5 0.11 12.4 1.7 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KLO12160.1 - 2.1e-06 27.3 0.9 0.00094 18.8 1.0 3.0 2 1 0 2 2 2 2 TPR repeat TPR_19 PF14559.6 KLO12160.1 - 0.00017 22.0 5.4 0.12 12.9 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KLO12160.1 - 0.00025 21.2 2.9 0.44 11.0 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KLO12160.1 - 0.03 15.1 5.0 8.5 7.5 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KLO12160.1 - 0.63 10.7 11.6 1.2 9.9 0.8 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KLO12160.1 - 1.5 8.9 6.0 3.9 7.6 2.8 3.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Response_reg PF00072.24 KLO12161.1 - 2.7e-21 75.8 0.0 5.5e-21 74.8 0.0 1.5 1 1 0 1 1 1 1 Response regulator receiver domain 4HBT_2 PF13279.6 KLO12162.1 - 8e-06 26.3 0.0 1.5e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily PTR2 PF00854.21 KLO12163.1 - 4.4e-78 262.9 6.8 6.4e-78 262.3 6.8 1.2 1 0 0 1 1 1 1 POT family Glyco_hydro_79C PF16862.5 KLO12164.1 - 3.5e-17 63.2 2.5 5.5e-17 62.5 1.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain ABC_membrane PF00664.23 KLO12165.1 - 2.1e-48 165.3 22.1 6.6e-26 91.6 4.6 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KLO12165.1 - 3.6e-47 160.3 0.0 1e-28 100.5 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KLO12165.1 - 8.2e-07 28.7 0.2 0.0023 17.4 1.0 3.4 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KLO12165.1 - 5.1e-06 26.5 1.4 0.19 11.5 0.0 4.5 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KLO12165.1 - 7.4e-06 25.7 0.7 0.0075 15.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 KLO12165.1 - 2.4e-05 23.5 0.3 0.16 11.0 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KLO12165.1 - 0.00065 19.4 0.3 0.29 10.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KLO12165.1 - 0.0012 19.3 1.9 1.1 9.6 1.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KLO12165.1 - 0.0034 17.6 1.4 18 5.6 0.1 3.6 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KLO12165.1 - 0.048 13.7 0.1 0.18 11.9 0.1 2.0 1 0 0 1 1 1 0 Helicase HerA, central domain RseC_MucC PF04246.12 KLO12165.1 - 0.085 12.8 0.0 0.52 10.3 0.0 2.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC AAA_23 PF13476.6 KLO12165.1 - 0.088 13.3 1.4 7.7 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 KLO12165.1 - 0.14 11.6 0.1 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Baculo_PEP_C PF04513.12 KLO12165.1 - 0.15 12.1 0.2 0.33 11.0 0.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1435 PF07256.12 KLO12165.1 - 0.16 12.1 0.0 0.16 12.1 0.0 2.6 3 0 0 3 3 1 0 Protein of unknown function (DUF1435) ADH_N PF08240.12 KLO12166.1 - 2.4e-25 88.6 8.4 4.6e-25 87.6 8.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO12166.1 - 4.5e-25 88.1 0.4 4.5e-25 88.1 0.4 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO12166.1 - 0.00017 22.6 0.1 0.00033 21.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KLO12166.1 - 0.0053 16.2 1.1 0.011 15.2 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase DUF5641 PF18701.1 KLO12167.1 - 0.19 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5641) DUF2457 PF10446.9 KLO12167.1 - 2.2 7.3 4.0 2.8 7.0 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Gti1_Pac2 PF09729.9 KLO12170.1 - 1.2e-30 107.0 3.0 6.5e-29 101.3 0.8 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family DUF4588 PF15251.6 KLO12171.1 - 0.00021 21.2 3.0 0.00074 19.4 3.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) F-box PF00646.33 KLO12172.1 - 9.1e-06 25.4 1.7 1.7e-05 24.5 0.0 2.4 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KLO12172.1 - 0.00095 19.0 1.5 0.0045 16.9 0.1 2.4 2 0 0 2 2 2 1 F-box-like Git3 PF11710.8 KLO12173.1 - 5.9e-07 29.5 8.6 1.7e-06 27.9 8.6 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KLO12173.1 - 0.00012 22.1 0.9 0.00032 20.7 0.9 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term HATPase_c PF02518.26 KLO12174.1 - 4.3e-20 72.3 0.0 1.1e-19 71.0 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KLO12174.1 - 3.6e-17 62.5 0.1 5.9e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 KLO12174.1 - 3.3e-06 27.0 0.7 1.3e-05 25.1 0.0 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain ISN1 PF06437.11 KLO12174.1 - 0.11 11.4 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase DUF2207 PF09972.9 KLO12175.1 - 0.11 11.3 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LapA_dom PF06305.11 KLO12175.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pkinase_Tyr PF07714.17 KLO12176.1 - 3.6e-52 177.2 0.0 5.4e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO12176.1 - 7.3e-36 123.9 0.0 1.3e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KLO12176.1 - 5.5e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO12176.1 - 0.00034 20.3 0.0 0.00077 19.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family TPR_12 PF13424.6 KLO12176.1 - 0.023 15.0 0.2 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat APH PF01636.23 KLO12176.1 - 0.069 13.1 0.0 0.26 11.2 0.0 2.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_S9 PF00326.21 KLO12177.1 - 6.3e-40 136.9 0.0 9.9e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KLO12177.1 - 2.8e-14 53.2 0.0 1.1e-13 51.3 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KLO12177.1 - 3e-07 30.5 0.0 0.025 14.4 0.0 2.5 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KLO12177.1 - 6.1e-06 25.7 0.0 0.0096 15.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KLO12177.1 - 0.00012 22.0 0.1 0.0017 18.3 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold PD40 PF07676.12 KLO12177.1 - 0.0061 16.5 1.2 0.023 14.6 0.2 2.4 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat LIP PF03583.14 KLO12177.1 - 0.03 13.6 0.0 0.57 9.4 0.1 2.2 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_4 PF08386.10 KLO12177.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Esterase_phd PF10503.9 KLO12177.1 - 0.12 11.9 0.3 0.33 10.4 0.3 1.7 1 1 0 1 1 1 0 Esterase PHB depolymerase AXE1 PF05448.12 KLO12177.1 - 0.18 10.4 0.0 3 6.4 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2721 PF11026.8 KLO12178.1 - 4.3 7.2 8.6 1.6 8.6 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) Phage_SSB PF16773.5 KLO12182.1 - 0.052 13.6 0.0 0.078 13.0 0.0 1.2 1 0 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein Cpn60_TCP1 PF00118.24 KLO12184.1 - 1.6e-86 290.9 6.9 2.8e-86 290.1 6.9 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rubella_E2 PF05749.11 KLO12184.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Glyco_hydro_18 PF00704.28 KLO12185.1 - 3.1e-22 79.7 3.8 1e-21 78.0 3.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KLO12185.1 - 0.013 16.1 5.9 0.013 16.1 5.9 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain SecY PF00344.20 KLO12186.1 - 3.7e-70 236.6 8.5 5.4e-70 236.1 8.5 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KLO12186.1 - 5e-19 67.8 0.2 2.2e-18 65.8 0.2 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p DUF3817 PF12823.7 KLO12186.1 - 0.012 16.4 0.3 4.3 8.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) DUF5336 PF17270.2 KLO12186.1 - 0.4 10.3 0.0 0.4 10.3 0.0 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF5336) DUF805 PF05656.14 KLO12186.1 - 2.2 8.7 5.0 1.7 9.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF805) Ribonuclease_3 PF00636.26 KLO12187.1 - 8.9e-41 138.8 0.0 6.6e-20 71.7 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KLO12187.1 - 1.6e-22 80.0 1.5 1.2e-08 35.2 0.1 4.7 3 2 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KLO12187.1 - 1.2e-20 73.4 0.0 5.1e-20 71.4 0.0 2.1 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 KLO12187.1 - 3.4e-15 56.2 0.0 6.6e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO12187.1 - 1.2e-13 51.4 0.0 3.8e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO12187.1 - 1.8e-12 47.6 0.0 3.2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit JmjC PF02373.22 KLO12188.1 - 2.1e-38 131.3 0.1 4.2e-38 130.3 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KLO12188.1 - 2.9e-15 55.9 0.1 5.5e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 KLO12188.1 - 1.1e-13 51.3 2.2 1.5e-13 50.8 0.8 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KLO12188.1 - 6.8e-10 39.1 5.0 6.8e-10 39.1 5.0 2.3 2 1 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 KLO12188.1 - 0.00089 19.1 4.9 0.0022 17.8 4.9 1.7 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.8 KLO12188.1 - 0.13 12.5 2.5 0.29 11.4 2.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Ribosomal_60s PF00428.19 KLO12190.1 - 5.8e-30 103.7 13.0 6.9e-30 103.5 13.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 KLO12190.1 - 0.068 11.6 0.8 0.064 11.7 0.8 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF2057 PF09829.9 KLO12190.1 - 0.17 12.0 0.4 0.19 11.9 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) ATG7_N PF16420.5 KLO12191.1 - 6.8e-92 308.3 0.0 8.8e-92 307.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KLO12191.1 - 7.1e-45 153.3 0.0 1.2e-44 152.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KLO12191.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Mit_KHE1 PF10173.9 KLO12193.1 - 1.5e-46 158.9 0.0 2.3e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Amidohydro_3 PF07969.11 KLO12194.1 - 0.00028 20.5 0.1 1.3 8.4 0.1 2.9 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KLO12194.1 - 0.021 14.1 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase family GMC_oxred_N PF00732.19 KLO12196.1 - 4.6e-65 219.9 0.0 6e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO12196.1 - 8.5e-35 120.4 0.0 1.7e-34 119.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KLO12196.1 - 4.4e-05 23.6 0.5 0.00034 20.8 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO12196.1 - 0.00026 20.7 0.5 0.021 14.4 0.2 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KLO12196.1 - 0.00053 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KLO12196.1 - 0.00063 18.9 0.6 0.049 12.7 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KLO12196.1 - 0.00076 18.6 0.1 0.0011 18.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KLO12196.1 - 0.0023 17.2 0.1 0.067 12.4 0.0 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO12196.1 - 0.0066 15.7 0.4 1.2 8.3 0.2 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase CoA_binding_3 PF13727.6 KLO12196.1 - 0.066 13.2 0.0 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 CoA-binding domain HI0933_like PF03486.14 KLO12196.1 - 0.12 11.1 0.1 0.35 9.5 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein DLH PF01738.18 KLO12197.1 - 1.1e-20 74.2 0.0 1.9e-20 73.4 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Dabb PF07876.12 KLO12198.1 - 4.9e-17 62.3 0.0 5.4e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain F-actin_cap_A PF01267.17 KLO12199.1 - 5.1e-103 344.1 0.0 5.8e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF2851 PF11013.8 KLO12199.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2851) MarC PF01914.17 KLO12202.1 - 0.00068 19.1 0.2 0.00068 19.1 0.2 1.7 2 0 0 2 2 2 1 MarC family integral membrane protein ATP-synt_F6 PF05511.11 KLO12205.1 - 0.096 13.1 0.0 0.1 13.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 PROCN PF08083.11 KLO12212.1 - 4.9e-212 704.0 7.4 1.5e-211 702.4 6.0 2.4 2 1 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KLO12212.1 - 4.2e-126 419.2 0.7 8.1e-126 418.3 0.7 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KLO12212.1 - 1.2e-87 291.9 2.3 1.2e-87 291.9 2.3 2.0 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KLO12212.1 - 9.6e-85 282.1 2.4 9.6e-85 282.1 2.4 2.9 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KLO12212.1 - 6.8e-74 246.3 0.1 1.3e-73 245.4 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KLO12212.1 - 4.3e-47 158.4 0.5 9.6e-47 157.3 0.5 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KLO12212.1 - 7e-42 142.2 0.0 1.6e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 KLO12212.1 - 0.0021 18.0 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Corona_5a PF06336.11 KLO12212.1 - 0.025 14.6 0.1 0.084 12.9 0.1 1.9 1 0 0 1 1 1 0 Coronavirus 5a protein SIKE PF05769.11 KLO12213.1 - 2.7e-05 24.2 12.8 0.0025 17.8 6.0 2.3 2 0 0 2 2 2 2 SIKE family Nsp1_C PF05064.13 KLO12213.1 - 0.012 15.5 1.7 0.012 15.5 1.7 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF4461 PF14688.6 KLO12213.1 - 0.027 14.3 0.9 0.027 14.3 0.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4461) YabA PF06156.13 KLO12213.1 - 0.19 12.4 7.6 1.3 9.7 3.1 3.2 2 1 1 3 3 3 0 Initiation control protein YabA Cnn_1N PF07989.11 KLO12213.1 - 0.53 10.5 7.0 1.8 8.7 0.4 3.2 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Rho_N PF07498.12 KLO12214.1 - 5.9e-05 22.9 0.2 0.00012 21.9 0.2 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.27 KLO12214.1 - 0.011 15.5 0.1 0.033 14.0 0.1 1.8 1 0 0 1 1 1 0 SAP domain F-box PF00646.33 KLO12214.1 - 0.06 13.2 0.0 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 F-box domain MOR2-PAG1_C PF14225.6 KLO12215.1 - 0.0095 15.8 0.2 0.016 15.1 0.2 1.3 1 0 0 1 1 1 1 Cell morphogenesis C-terminal FAD_binding_3 PF01494.19 KLO12216.1 - 7.8e-20 71.4 0.0 5.9e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KLO12216.1 - 0.005 17.0 0.1 0.012 15.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO12216.1 - 0.0061 15.8 0.1 0.28 10.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KLO12216.1 - 0.019 15.0 0.1 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KLO12216.1 - 0.036 12.9 0.3 0.55 9.0 0.1 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Hom_end PF05204.14 KLO12216.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Homing endonuclease U6-snRNA_bdg PF10596.9 KLO12218.1 - 0.001 19.0 0.3 0.0016 18.5 0.3 1.3 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U6-snRNA_bdg PF10596.9 KLO12219.1 - 2.9e-17 63.1 0.0 4.2e-17 62.6 0.0 1.2 1 1 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PROCT PF08084.11 KLO12220.1 - 5.4e-10 39.3 0.0 8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 PROCT (NUC072) domain PRP8_domainIV PF12134.8 KLO12220.1 - 0.0017 18.0 0.0 0.0023 17.6 0.0 1.1 1 0 0 1 1 1 1 PRP8 domain IV core Zn_clus PF00172.18 KLO12222.1 - 7.7e-10 38.7 17.3 1.5e-09 37.8 17.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KLO12223.1 - 4.8e-42 144.1 0.8 1.7e-40 139.0 0.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO12223.1 - 3.3e-39 134.4 2.6 4.8e-39 133.8 1.1 1.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KLO12223.1 - 2.3e-07 30.9 0.6 4.1e-07 30.1 0.1 1.5 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 KLO12223.1 - 0.021 14.7 0.3 0.076 12.9 0.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KLO12223.1 - 0.098 12.1 0.1 3.5 7.0 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO12223.1 - 0.14 11.5 0.2 0.41 10.0 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase FAD_binding_2 PF00890.24 KLO12224.1 - 1.4e-45 156.2 0.4 4.9e-45 154.4 0.4 1.7 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KLO12224.1 - 3.3e-07 29.4 1.0 0.019 13.7 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 KLO12224.1 - 2e-06 27.4 0.5 0.0017 17.8 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO12224.1 - 7.4e-06 25.4 0.1 0.0081 15.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO12224.1 - 3.2e-05 23.7 8.0 0.00014 21.5 3.3 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KLO12224.1 - 0.00013 21.2 7.3 0.0018 17.4 0.4 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KLO12224.1 - 0.00034 20.8 0.1 0.0023 18.1 0.1 2.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 KLO12224.1 - 0.014 14.8 0.0 0.87 8.9 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase MCR_alpha PF02249.17 KLO12224.1 - 0.023 15.1 0.0 8.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Pyr_redox_3 PF13738.6 KLO12224.1 - 0.061 12.6 0.0 0.5 9.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4449 PF14613.6 KLO12225.1 - 3.5e-40 137.8 4.5 1e-39 136.3 0.9 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) NMO PF03060.15 KLO12226.1 - 1.3e-59 202.3 2.6 8.4e-59 199.6 2.6 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KLO12226.1 - 5.9e-11 42.0 0.2 3.5e-08 32.8 0.2 2.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 KLO12226.1 - 0.013 14.9 0.2 0.025 13.9 0.2 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase FMN_dh PF01070.18 KLO12226.1 - 0.039 13.0 1.1 0.063 12.3 1.1 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 KLO12226.1 - 0.083 12.3 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein AhpC-TSA PF00578.21 KLO12227.1 - 1.1e-31 109.3 0.0 1.6e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KLO12227.1 - 5e-20 71.7 0.0 8.5e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KLO12227.1 - 0.0008 19.5 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.6 KLO12227.1 - 0.0085 16.4 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like PRCC PF10253.9 KLO12227.1 - 0.28 11.9 8.6 0.45 11.3 8.6 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SARG PF15385.6 KLO12227.1 - 1.4 8.0 11.4 2 7.6 11.4 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein SUR7 PF06687.12 KLO12228.1 - 1.4e-08 34.6 0.0 5.2e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.9 KLO12228.1 - 0.45 9.2 1.7 0.41 9.3 0.2 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DAHP_synth_1 PF00793.20 KLO12229.1 - 5.2e-100 333.8 0.0 6.6e-100 333.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-Tim10_DDP PF02953.15 KLO12230.1 - 1.3e-18 66.3 3.9 1.7e-18 66.0 3.6 1.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Lactamase_B PF00753.27 KLO12234.1 - 3.2e-12 46.9 0.1 4.4e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KLO12234.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain F-box-like PF12937.7 KLO12235.1 - 4.1e-05 23.4 0.0 0.00016 21.5 0.0 2.1 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO12236.1 - 3.1e-06 27.0 0.2 9.9e-06 25.4 0.2 1.9 1 0 0 1 1 1 1 F-box-like Acetyltransf_1 PF00583.25 KLO12237.1 - 0.00011 22.4 0.0 0.0007 19.8 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KLO12237.1 - 0.0023 18.3 0.0 0.01 16.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO12237.1 - 0.027 14.4 0.0 13 5.8 0.0 2.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain EI24 PF07264.11 KLO12239.1 - 0.2 11.9 8.6 0.15 12.3 7.3 1.3 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) PLDc PF00614.22 KLO12240.1 - 3.5e-13 49.1 0.2 1.6e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KLO12240.1 - 2.9e-12 46.6 0.0 3.8e-06 26.8 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 KLO12240.1 - 5.4e-12 45.7 0.2 4.2e-09 36.4 0.0 3.6 3 0 0 3 3 3 2 PX domain Abhydrolase_3 PF07859.13 KLO12241.1 - 7.4e-05 22.7 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lactamase_B PF00753.27 KLO12242.1 - 3.3e-09 37.0 3.9 6.6e-09 36.1 3.9 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KLO12242.1 - 0.021 14.3 0.6 0.05 13.1 0.2 1.8 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Pkinase PF00069.25 KLO12243.1 - 1.1e-54 185.6 0.0 1.3e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12243.1 - 1.4e-25 90.1 0.9 5.4e-24 84.9 0.9 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO12243.1 - 3.7e-05 23.2 0.1 0.00013 21.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KLO12243.1 - 0.00032 20.1 0.5 0.00048 19.5 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO12243.1 - 0.0011 18.7 2.1 0.0073 15.9 0.2 2.6 3 0 0 3 3 3 1 RIO1 family FTA2 PF13095.6 KLO12243.1 - 0.011 15.4 0.2 0.57 9.8 0.1 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KLO12243.1 - 0.033 14.1 0.0 1.4 8.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO12243.1 - 0.055 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase IATP PF04568.12 KLO12244.1 - 0.08 13.4 0.9 0.14 12.6 0.9 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Casc1_N PF15927.5 KLO12244.1 - 9.3 5.9 14.5 13 5.4 14.5 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus vATP-synt_AC39 PF01992.16 KLO12245.1 - 1.3e-118 396.3 0.1 1.5e-118 396.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TLP1_add_C PF18313.1 KLO12245.1 - 0.15 12.0 0.0 0.68 9.9 0.0 2.0 3 0 0 3 3 3 0 Thiolase-like protein type 1 additional C-terminal domain Wzy_C_2 PF11846.8 KLO12246.1 - 0.01 15.7 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DNA_pol_phi PF04931.13 KLO12246.1 - 2.3 6.2 12.2 3.6 5.6 12.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Adaptin_N PF01602.20 KLO12249.1 - 1e-18 67.2 0.2 3.9e-18 65.3 0.2 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cohesin_HEAT PF12765.7 KLO12249.1 - 0.0043 17.3 0.3 0.023 15.0 0.1 2.5 1 1 1 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KLO12249.1 - 0.0075 16.3 0.6 0.023 14.7 0.1 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KLO12249.1 - 0.011 15.9 0.1 1.1 9.7 0.1 3.4 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 KLO12249.1 - 0.075 13.4 0.8 0.68 10.4 0.8 2.7 2 0 0 2 2 2 0 HEAT repeats Carboxyl_trans PF01039.22 KLO12250.1 - 6.8e-134 447.2 0.0 8.7e-134 446.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CcmD PF04995.14 KLO12251.1 - 0.19 11.9 0.2 0.41 10.8 0.2 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Chromate_transp PF02417.15 KLO12252.1 - 0.0026 17.9 1.5 0.013 15.6 1.5 2.0 1 1 0 1 1 1 1 Chromate transporter HMMR_C PF15908.5 KLO12253.1 - 4.2e-05 23.9 3.1 4.2e-05 23.9 3.1 5.0 2 2 4 6 6 6 1 Hyaluronan mediated motility receptor C-terminal Spc7 PF08317.11 KLO12253.1 - 0.00035 19.6 13.7 0.00035 19.6 13.7 5.2 1 1 3 5 5 5 3 Spc7 kinetochore protein Tup_N PF08581.10 KLO12253.1 - 0.017 15.4 2.1 0.017 15.4 2.1 6.2 6 0 0 6 6 6 0 Tup N-terminal SMP_2 PF10144.9 KLO12253.1 - 0.43 10.2 15.7 0.14 11.8 0.5 3.6 3 1 1 4 4 4 0 Bacterial virulence factor haemolysin HALZ PF02183.18 KLO12253.1 - 1.5 9.1 20.6 0.06 13.6 5.4 5.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper PPR_2 PF13041.6 KLO12254.1 - 2.6e-40 136.4 0.0 2.2e-08 34.2 0.0 8.5 4 3 4 8 8 8 8 PPR repeat family PPR_3 PF13812.6 KLO12254.1 - 2.2e-38 130.1 0.0 1.2e-08 34.9 0.0 7.6 5 2 4 9 9 9 8 Pentatricopeptide repeat domain PPR_long PF17177.4 KLO12254.1 - 3.4e-19 69.1 0.4 1.1e-06 28.2 0.0 3.3 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KLO12254.1 - 1.2e-13 50.4 0.5 0.013 15.2 0.0 7.3 8 0 0 8 8 8 4 PPR repeat PPR PF01535.20 KLO12254.1 - 3e-13 49.0 6.2 0.0043 17.2 0.0 9.6 10 1 0 10 10 10 1 PPR repeat DUF1018 PF06252.12 KLO12254.1 - 0.0022 19.0 0.1 1.7 9.7 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1018) TPR_14 PF13428.6 KLO12254.1 - 0.0097 16.7 0.4 52 5.0 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat ECSIT PF06239.11 KLO12254.1 - 0.011 14.9 0.0 0.88 8.6 0.0 3.8 3 2 2 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway Exog_C PF18026.1 KLO12254.1 - 0.053 13.6 0.1 5.2 7.2 0.0 3.6 4 0 0 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain Rad21_Rec8_N PF04825.13 KLO12255.1 - 2.9e-36 124.0 0.1 5e-36 123.2 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KLO12255.1 - 2.9e-11 42.5 0.0 5.4e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Glyco_hydro_16 PF00722.21 KLO12256.1 - 6.1e-05 22.6 0.0 0.00016 21.2 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Asp PF00026.23 KLO12257.1 - 1.4e-69 235.0 1.1 1.7e-69 234.7 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO12257.1 - 3.2e-09 37.3 5.3 1.2e-05 25.6 0.2 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal RhoGAP PF00620.27 KLO12258.1 - 3.9e-43 146.9 0.0 6.9e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KLO12258.1 - 9.2e-18 64.2 20.6 5.3e-11 42.6 1.0 2.9 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 KLO12258.1 - 0.00011 22.0 6.0 0.00011 22.0 6.0 3.7 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) TSNAXIP1_N PF15739.5 KLO12258.1 - 0.57 10.6 5.9 0.27 11.6 2.6 2.1 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus Cep57_MT_bd PF06657.13 KLO12258.1 - 6.9 7.2 13.6 29 5.2 1.4 5.2 5 0 0 5 5 5 0 Centrosome microtubule-binding domain of Cep57 PTPLA PF04387.14 KLO12259.1 - 1.5e-51 174.4 6.1 3.6e-51 173.2 6.0 1.7 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA CTF_NFI PF00859.18 KLO12259.1 - 0.066 13.1 4.9 2 8.2 1.0 2.2 2 0 0 2 2 2 0 CTF/NF-I family transcription modulation region BTB PF00651.31 KLO12260.1 - 4.6e-12 46.1 0.0 5.6e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain bZIP_1 PF00170.21 KLO12261.1 - 8.3e-06 25.8 7.7 8.3e-06 25.8 7.7 2.4 2 1 1 3 3 3 1 bZIP transcription factor SPESP1 PF15754.5 KLO12261.1 - 0.16 11.1 4.3 0.5 9.5 4.3 1.8 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 DUF4407 PF14362.6 KLO12261.1 - 1.2 8.5 14.8 4.5 6.5 14.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Metallophos PF00149.28 KLO12262.1 - 9.9e-26 91.5 0.0 6.4e-25 88.9 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 KLO12262.1 - 2.1e-25 88.8 0.0 4.1e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 KLO12262.1 - 2.6e-10 39.7 0.3 2e-06 27.4 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO12262.1 - 5.5e-07 29.2 0.3 4.4e-05 23.3 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KLO12262.1 - 6e-06 25.8 0.1 0.025 14.3 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 KLO12262.1 - 0.00084 19.4 0.6 0.00084 19.4 0.6 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KLO12262.1 - 0.004 17.4 0.7 1.7 9.2 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KLO12262.1 - 0.013 16.0 1.0 5.2 7.7 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 KLO12262.1 - 0.014 14.7 0.1 0.028 13.7 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KLO12262.1 - 0.024 15.3 0.0 0.047 14.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KLO12262.1 - 0.19 12.0 0.1 3.6 8.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Metallophos PF00149.28 KLO12263.1 - 8.6e-23 81.9 0.0 3.4e-22 80.0 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 KLO12263.1 - 1.9e-10 40.9 0.0 3.1e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region Alpha-L-AF_C PF06964.12 KLO12264.1 - 9.2e-36 123.5 0.3 9.2e-36 123.5 0.3 1.6 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KLO12264.1 - 0.012 15.8 0.6 0.037 14.3 0.6 1.9 1 0 0 1 1 1 0 Carbohydrate binding domain MMR_HSR1_Xtn PF16897.5 KLO12265.1 - 0.035 14.1 0.4 0.7 9.9 0.3 2.3 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain DUF1863 PF08937.11 KLO12266.1 - 0.083 13.2 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) MMR_HSR1_Xtn PF16897.5 KLO12266.1 - 0.26 11.3 2.0 0.83 9.7 1.0 2.1 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain PLA2_B PF01735.18 KLO12267.1 - 1.1e-99 334.1 0.2 1.4e-99 333.7 0.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain MGC-24 PF05283.11 KLO12267.1 - 0.0055 17.2 0.2 0.017 15.5 0.0 1.9 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin UBA PF00627.31 KLO12268.1 - 1.2e-25 88.9 3.7 1.1e-14 54.0 0.6 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KLO12268.1 - 2.4e-21 75.2 0.5 3.5e-21 74.7 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 KLO12268.1 - 2.2e-13 49.7 9.2 2.2e-13 49.7 9.2 2.0 2 0 0 2 2 2 1 XPC-binding domain Rad60-SLD PF11976.8 KLO12268.1 - 2.6e-09 36.8 1.0 5.1e-09 35.8 1.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KLO12268.1 - 0.0086 16.4 0.1 0.016 15.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 KLO12268.1 - 0.0086 16.6 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain BRCT_2 PF16589.5 KLO12268.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Rad60-SLD_2 PF13881.6 KLO12268.1 - 0.015 15.4 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KLO12268.1 - 0.062 13.1 0.0 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Ubiquitin_2 PF14560.6 KLO12268.1 - 0.12 12.8 0.2 0.2 12.1 0.2 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain STI1 PF17830.1 KLO12268.1 - 0.39 10.7 6.8 3.9 7.5 4.5 2.9 2 1 0 2 2 2 0 STI1 domain LRR_4 PF12799.7 KLO12269.1 - 2.8e-09 37.1 9.8 0.0092 16.4 0.5 4.9 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KLO12269.1 - 4.6e-08 32.7 19.4 3.6e-06 26.6 7.8 3.8 4 0 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 KLO12269.1 - 0.072 12.6 0.5 0.17 11.4 0.5 1.6 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 KLO12269.1 - 9.7 7.2 14.5 3.1e+02 2.6 0.1 6.8 6 0 0 6 6 6 0 Leucine Rich Repeat Arf PF00025.21 KLO12270.1 - 8.4e-78 259.8 0.0 9.5e-78 259.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KLO12270.1 - 9.7e-15 54.8 0.0 1.3e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KLO12270.1 - 2.5e-13 49.9 0.0 2.7e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KLO12270.1 - 9.8e-12 44.7 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KLO12270.1 - 1.1e-11 44.5 1.7 4.3e-07 29.4 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KLO12270.1 - 1.3e-08 34.5 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KLO12270.1 - 0.00026 21.0 0.0 0.00045 20.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KLO12270.1 - 0.0054 16.1 0.1 0.0095 15.3 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase DLIC PF05783.11 KLO12270.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) PALP PF00291.25 KLO12271.1 - 3.1e-69 233.6 0.3 3.6e-69 233.4 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3602 PF12223.8 KLO12272.1 - 1.7e-07 31.7 9.4 0.0024 18.4 0.8 4.2 3 1 0 3 3 3 2 Protein of unknown function (DUF3602) F-box-like PF12937.7 KLO12273.1 - 2e-08 34.0 0.0 5.8e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO12274.1 - 7.5e-09 35.3 0.0 1.6e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO12274.1 - 0.023 14.6 0.0 0.098 12.6 0.0 2.1 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.7 KLO12274.1 - 0.023 15.1 0.1 8.5 7.0 0.0 4.0 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO12275.1 - 1.2e-11 44.3 1.4 1.2e-09 37.9 0.0 2.6 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KLO12275.1 - 0.11 12.4 7.1 3 7.9 0.7 3.2 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO12276.1 - 5.3e-10 39.0 0.1 1.3e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like Glyoxal_oxid_N PF07250.11 KLO12277.1 - 7.6e-36 123.5 0.6 8.3e-28 97.2 0.0 3.2 2 1 1 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KLO12277.1 - 7.1e-24 83.9 0.1 1.6e-23 82.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KLO12277.1 - 1.1 9.3 5.2 19 5.4 0.1 3.8 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.15 KLO12277.1 - 4.6 7.4 6.6 4.5 7.4 0.1 3.6 4 0 0 4 4 4 0 Kelch motif Glyoxal_oxid_N PF07250.11 KLO12283.1 - 2.6e-35 121.7 0.1 1.6e-27 96.3 0.0 3.0 3 1 1 4 4 4 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KLO12283.1 - 2e-23 82.5 0.3 4.5e-23 81.4 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KLO12283.1 - 0.065 13.2 0.7 4.2 7.4 0.1 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Pkinase PF00069.25 KLO12284.1 - 6.4e-17 61.8 0.0 5e-16 58.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12284.1 - 5.9e-12 45.4 0.0 3.3e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KLO12284.1 - 0.00023 21.2 0.1 0.0021 18.0 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO12284.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KLO12284.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cupredoxin_1 PF13473.6 KLO12285.1 - 0.065 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Cupredoxin-like domain Copper-bind PF00127.20 KLO12285.1 - 0.094 13.2 0.0 0.24 11.8 0.0 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family FSA_C PF10479.9 KLO12285.1 - 4 5.4 7.9 5.2 5.1 7.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Herpes_gE PF02480.16 KLO12286.1 - 0.0001 21.2 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Shisa PF13908.6 KLO12286.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.3 2 2 0 2 2 2 0 Wnt and FGF inhibitory regulator MGC-24 PF05283.11 KLO12286.1 - 6.8 7.1 8.3 0.55 10.7 2.7 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Myf5 PF12232.8 KLO12287.1 - 0.033 15.0 9.2 0.065 14.0 0.6 2.5 2 0 0 2 2 2 0 Myogenic determination factor 5 Sporozoite_P67 PF05642.11 KLO12287.1 - 0.33 9.0 6.4 0.33 9.0 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_capsid PF06112.11 KLO12287.1 - 0.84 9.7 6.6 1.4 9.0 6.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SKG6 PF08693.10 KLO12289.1 - 3.4e-05 23.1 0.5 9.5e-05 21.7 0.5 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 KLO12289.1 - 0.09 13.2 9.1 0.42 11.0 9.1 2.1 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 KLO12289.1 - 0.13 12.2 17.5 0.27 11.2 17.5 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein TMEM154 PF15102.6 KLO12289.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family SR-25 PF10500.9 KLO12289.1 - 0.84 9.2 5.8 1.3 8.6 5.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Surp PF01805.20 KLO12290.1 - 1.1e-13 50.9 0.1 3.4e-13 49.4 0.1 1.8 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 KLO12290.1 - 1.9e-08 34.0 0.0 0.007 16.2 0.0 2.8 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 KLO12290.1 - 0.0037 18.1 0.4 0.013 16.3 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CAF1-p150_C2 PF15539.6 KLO12290.1 - 0.024 14.1 0.1 0.051 13.0 0.1 1.4 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term RSRP PF17069.5 KLO12290.1 - 0.14 11.7 52.9 0.56 9.7 52.9 2.0 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 KH_1 PF00013.29 KLO12291.1 - 8.7e-91 297.8 26.9 2.8e-13 49.5 1.3 13.9 13 1 0 13 13 13 10 KH domain KH_2 PF07650.17 KLO12291.1 - 7.6e-12 44.9 15.2 0.025 14.4 0.8 7.4 5 2 1 6 6 6 5 KH domain SLS PF14611.6 KLO12291.1 - 3.4e-07 30.3 25.4 0.11 12.4 0.1 6.9 5 2 0 6 6 6 5 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 KLO12291.1 - 3e-06 27.0 5.1 3.4 7.6 0.0 6.6 6 0 0 6 6 6 3 KH domain KH_5 PF13184.6 KLO12291.1 - 0.00012 22.1 12.7 0.66 10.1 0.4 5.2 6 1 0 6 6 6 3 NusA-like KH domain FCD PF07729.12 KLO12291.1 - 0.004 17.6 0.3 0.083 13.3 0.0 3.4 4 0 0 4 4 4 1 FCD domain Dehydrin PF00257.19 KLO12291.1 - 5.6 7.5 7.6 0.75 10.3 2.6 2.1 2 0 0 2 2 2 0 Dehydrin TRAM_LAG1_CLN8 PF03798.16 KLO12293.1 - 3.1e-05 23.8 7.0 6.2e-05 22.8 6.9 1.6 1 1 0 1 1 1 1 TLC domain TetR_C_21 PF17926.1 KLO12293.1 - 0.023 14.8 0.1 0.083 13.0 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain GST_N_3 PF13417.6 KLO12296.1 - 2.1e-11 44.1 0.0 6.5e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO12296.1 - 7.9e-10 38.9 0.0 1.4e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO12296.1 - 2.1e-08 34.1 0.0 3.7e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KLO12296.1 - 0.00015 21.5 0.0 0.00033 20.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KLO12296.1 - 0.00025 21.3 0.0 0.002 18.4 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO12296.1 - 0.0014 18.8 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO12296.1 - 0.0075 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KLO12296.1 - 0.14 12.9 0.0 6.5 7.6 0.0 2.3 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain Redoxin PF08534.10 KLO12298.1 - 1.4e-34 118.9 0.0 1.6e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KLO12298.1 - 1.5e-11 44.3 0.0 1.6e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family FAD_syn PF06574.12 KLO12298.1 - 0.096 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase HMG_box PF00505.19 KLO12299.1 - 3.7e-19 68.9 8.2 8.8e-10 38.9 0.2 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO12299.1 - 6.9e-12 45.8 10.2 2.9e-06 27.8 0.3 3.0 3 0 0 3 3 3 2 HMG-box domain DUF1564 PF07600.11 KLO12299.1 - 3.7 7.2 5.8 0.23 11.1 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) GST_N_3 PF13417.6 KLO12300.1 - 5e-08 33.2 0.1 9.7e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO12300.1 - 4e-07 30.2 0.1 7.8e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO12300.1 - 0.0064 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO12300.1 - 0.046 13.9 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KLO12300.1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ORC5_C PF14630.6 KLO12301.1 - 1e-46 159.7 0.0 1.3e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus PhzC-PhzF PF02567.16 KLO12302.1 - 5e-62 209.9 0.0 6.1e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein HPTransfase PF10090.9 KLO12302.1 - 0.028 14.2 0.1 2.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain GST_N_3 PF13417.6 KLO12303.1 - 9e-16 58.1 0.0 3.1e-13 49.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO12303.1 - 3.6e-11 43.2 0.0 7.4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO12303.1 - 5.4e-08 32.8 0.3 1.1e-07 31.7 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KLO12303.1 - 2.4e-06 28.1 0.0 4.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO12303.1 - 0.00085 19.5 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KLO12303.1 - 0.0012 19.0 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KLO12303.1 - 0.039 14.3 0.0 0.48 10.8 0.0 2.6 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KLO12304.1 - 7.6e-10 39.1 0.0 3.8e-09 36.8 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO12304.1 - 2.5e-09 37.3 0.0 4.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO12304.1 - 0.0008 19.4 0.2 0.0037 17.2 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KLO12304.1 - 0.008 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO12304.1 - 0.028 14.6 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KLO12304.1 - 0.11 12.9 0.0 0.85 10.0 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KLO12305.1 - 4e-11 43.1 0.0 1.4e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO12305.1 - 2.9e-09 37.1 0.0 5.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KLO12305.1 - 0.00014 22.0 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KLO12305.1 - 0.00014 22.0 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KLO12305.1 - 0.026 15.1 0.0 0.051 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KLO12305.1 - 0.03 14.4 0.1 0.081 13.0 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain LRR_RI_capping PF18779.1 KLO12305.1 - 0.053 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat Med8 PF10232.9 KLO12306.1 - 0.00018 21.2 0.1 0.00031 20.4 0.1 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 GST_N_2 PF13409.6 KLO12307.1 - 3.8e-05 23.9 0.0 7.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KLO12307.1 - 9.6e-05 22.7 0.0 0.0015 18.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KLO12307.1 - 0.0056 16.8 0.0 0.0088 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KLO12307.1 - 0.025 15.1 0.0 0.045 14.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KLO12307.1 - 0.039 14.0 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ADH_zinc_N PF00107.26 KLO12308.1 - 1e-23 83.8 0.0 1.6e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KLO12308.1 - 1.9e-14 53.4 0.0 4.3e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KLO12308.1 - 0.0075 17.3 0.0 0.012 16.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KLO12308.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain ADH_zinc_N PF00107.26 KLO12309.1 - 1.8e-21 76.5 0.0 3e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KLO12309.1 - 1.8e-15 56.8 0.0 3.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase DUF2855 PF11017.8 KLO12309.1 - 0.0041 16.9 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) TrkA_N PF02254.18 KLO12309.1 - 0.016 15.4 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain DUF824 PF05688.11 KLO12309.1 - 0.025 14.4 1.1 1.7 8.5 0.1 3.0 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) PhoLip_ATPase_C PF16212.5 KLO12310.1 - 1.3e-73 247.8 25.4 1.3e-73 247.8 25.4 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KLO12310.1 - 2.3e-21 75.2 0.2 2.3e-21 75.2 0.2 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KLO12310.1 - 3.7e-12 46.2 0.0 8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KLO12310.1 - 5e-12 46.5 0.7 4.1e-05 24.0 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KLO12310.1 - 3.4e-07 30.0 2.9 2.8e-06 27.0 0.0 3.3 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KLO12310.1 - 0.0036 17.1 0.1 0.024 14.4 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrophobin PF01185.18 KLO12311.1 - 5.4e-08 33.4 3.5 1e-07 32.4 3.6 1.4 1 1 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KLO12312.1 - 6.2e-10 39.6 12.0 1e-09 38.9 12.0 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KLO12313.1 - 3e-12 47.0 6.9 4e-12 46.6 6.9 1.2 1 0 0 1 1 1 1 Fungal hydrophobin RNase_P_p30 PF01876.16 KLO12317.1 - 3.6e-38 131.2 0.1 4.9e-38 130.7 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Cytomega_TRL10 PF06084.11 KLO12318.1 - 0.077 13.0 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein zf-C2H2 PF00096.26 KLO12318.1 - 1.3 9.7 9.1 2.1 9.0 3.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type PRiA4_ORF3 PF07929.11 KLO12320.1 - 1.3e-26 93.4 0.2 3.2e-26 92.1 0.2 1.6 2 0 0 2 2 2 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 KLO12320.1 - 9.1e-12 44.9 11.9 1.6e-11 44.1 11.9 1.4 1 0 0 1 1 1 1 MYND finger U3_snoRNA_assoc PF08297.11 KLO12323.1 - 0.0006 20.5 1.1 0.0006 20.5 1.1 2.8 2 0 0 2 2 2 1 U3 snoRNA associated GrpE PF01025.19 KLO12323.1 - 0.38 10.4 11.0 0.06 13.0 6.3 1.8 2 0 0 2 2 2 0 GrpE Peptidase_C14 PF00656.22 KLO12325.1 - 1.1e-53 182.7 0.0 1.7e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Zip PF02535.22 KLO12325.1 - 0.29 10.3 4.9 0.39 9.9 4.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_C14 PF00656.22 KLO12326.1 - 1.2e-37 130.2 0.0 3.1e-37 128.9 0.0 1.6 1 1 0 1 1 1 1 Caspase domain Synaptobrevin PF00957.21 KLO12328.1 - 6.6e-14 51.5 0.2 1e-13 50.8 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KLO12328.1 - 0.00012 22.0 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain MBOAT_2 PF13813.6 KLO12329.1 - 2.2e-12 47.1 2.5 2.2e-12 47.1 2.5 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF1616 PF07760.11 KLO12329.1 - 0.2 11.0 0.2 0.41 10.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) YCII PF03795.14 KLO12330.1 - 1.1e-06 28.9 0.0 1.4e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Sec23_trunk PF04811.15 KLO12331.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain DcpS PF05652.12 KLO12332.1 - 3.5e-26 92.1 0.0 7.7e-26 91.0 0.0 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KLO12332.1 - 2.4e-25 89.3 0.1 3.9e-25 88.5 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KLO12332.1 - 0.048 14.4 0.3 0.26 12.1 0.1 2.2 1 1 1 2 2 2 0 HIT domain Fer2_3 PF13085.6 KLO12334.1 - 1.4e-33 115.2 0.1 2.2e-33 114.5 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KLO12334.1 - 6.9e-10 39.3 7.3 6.9e-10 39.3 7.3 2.3 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KLO12334.1 - 5.2e-07 29.7 4.5 5.2e-07 29.7 4.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KLO12334.1 - 1.3e-06 28.8 8.0 1.3e-06 28.8 8.0 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KLO12334.1 - 0.00096 19.7 4.5 0.00096 19.7 4.5 2.3 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KLO12334.1 - 0.007 16.3 1.4 0.007 16.3 1.4 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 KLO12334.1 - 5.5 7.2 14.1 2.7 8.2 9.0 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain AhpC-TSA PF00578.21 KLO12335.1 - 1.9e-27 95.6 0.0 3.1e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KLO12335.1 - 1.9e-20 73.1 0.0 3e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin SPATA3 PF15662.5 KLO12335.1 - 0.031 14.9 0.6 0.71 10.5 0.6 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family AhpC-TSA_2 PF13911.6 KLO12335.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme adh_short_C2 PF13561.6 KLO12336.1 - 3.5e-53 180.6 0.1 6.2e-53 179.7 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO12336.1 - 7.6e-46 156.0 0.3 9.8e-46 155.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO12336.1 - 2.1e-10 40.8 0.6 3.9e-10 39.9 0.6 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO12336.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KLO12337.1 - 3.8e-58 196.8 6.5 4.8e-58 196.5 6.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO12337.1 - 5.1e-52 176.2 4.8 6.8e-52 175.8 4.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO12337.1 - 8.1e-14 51.9 4.1 1.3e-13 51.3 4.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO12337.1 - 0.0079 15.7 0.1 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KLO12337.1 - 0.009 15.9 1.6 0.016 15.1 1.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KLO12337.1 - 0.023 14.1 0.4 0.034 13.5 0.4 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KLO12337.1 - 0.023 13.9 1.1 0.037 13.2 1.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 KLO12337.1 - 0.035 14.3 0.7 0.056 13.6 0.7 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short_C2 PF13561.6 KLO12338.1 - 3.9e-51 173.9 2.1 8.4e-51 172.8 2.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO12338.1 - 1.8e-44 151.6 3.4 1.8e-43 148.3 3.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO12338.1 - 4.1e-09 36.6 1.2 7.1e-09 35.8 1.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO12338.1 - 0.014 14.8 0.1 0.032 13.7 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KLO12339.1 - 3.6e-57 193.6 0.5 5.7e-57 193.0 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO12339.1 - 4.3e-50 169.9 0.5 5.6e-50 169.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO12339.1 - 1.3e-08 34.9 0.9 1.9e-08 34.4 0.9 1.2 1 0 0 1 1 1 1 KR domain p450 PF00067.22 KLO12343.1 - 1.8e-61 208.4 0.0 2.2e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tetraspanin PF00335.20 KLO12344.1 - 0.026 14.2 7.9 0.054 13.2 7.9 1.5 1 0 0 1 1 1 0 Tetraspanin family Pex24p PF06398.11 KLO12344.1 - 0.13 11.2 2.3 0.25 10.3 0.4 2.1 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Sortilin-Vps10 PF15902.5 KLO12347.1 - 9.7e-275 911.2 6.7 1.3e-144 482.3 0.1 2.4 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KLO12347.1 - 1.2e-92 308.9 18.8 2.3e-50 171.3 6.6 2.5 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KLO12347.1 - 2.5e-11 41.8 44.3 1.8 8.9 0.9 12.2 11 0 0 11 11 11 7 BNR/Asp-box repeat BNR_2 PF13088.6 KLO12347.1 - 3.2e-05 23.4 7.2 0.67 9.2 0.0 6.6 4 2 1 5 5 5 1 BNR repeat-like domain Mo-co_dimer PF03404.16 KLO12347.1 - 0.0014 18.6 1.0 11 6.0 0.0 5.2 5 0 0 5 5 5 1 Mo-co oxidoreductase dimerisation domain CHB_HEX_C PF03174.13 KLO12347.1 - 0.0017 18.3 4.4 7.2 6.7 0.0 6.3 7 1 1 8 8 8 1 Chitobiase/beta-hexosaminidase C-terminal domain BNR_6 PF15899.5 KLO12347.1 - 0.045 13.8 3.3 12 6.3 0.1 4.6 3 0 0 3 3 3 0 BNR-Asp box repeat Fe_dep_repr_C PF02742.15 KLO12347.1 - 0.069 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Amidohydro_1 PF01979.20 KLO12348.1 - 1.6e-21 77.0 0.0 4.6e-17 62.3 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KLO12348.1 - 1.6e-10 41.1 0.1 1.6e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Glyco_hydro_16 PF00722.21 KLO12349.1 - 6.7e-18 64.8 0.7 1.2e-17 64.0 0.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Acyl-CoA_dh_N PF02771.16 KLO12350.1 - 2.1e-29 102.5 0.0 3.4e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KLO12350.1 - 3.8e-26 92.1 0.0 5.6e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KLO12350.1 - 9.3e-22 77.1 0.0 2e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KLO12350.1 - 1.8e-05 25.0 0.0 4.1e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Phage_tail_2 PF06199.11 KLO12351.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein His_Phos_1 PF00300.22 KLO12352.1 - 1.3e-23 83.7 0.0 1.9e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SHS2_Rpb7-N PF03876.17 KLO12353.1 - 5.3e-15 55.6 0.0 8.3e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KLO12353.1 - 8.3e-12 45.3 0.8 2e-11 44.0 0.8 1.6 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KLO12353.1 - 0.0064 16.7 0.1 0.012 15.8 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 MFS_1 PF07690.16 KLO12354.1 - 1.9e-47 161.9 40.7 5.8e-43 147.2 42.6 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily VirB8 PF04335.13 KLO12354.1 - 0.25 11.2 0.9 17 5.2 0.1 2.5 2 1 0 2 2 2 0 VirB8 protein Aminotran_4 PF01063.19 KLO12355.1 - 4.7e-27 95.3 0.0 1.1e-26 94.1 0.0 1.6 1 1 0 1 1 1 1 Amino-transferase class IV SDA1 PF05285.12 KLO12356.1 - 0.0034 16.9 14.9 0.0051 16.3 14.9 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 KLO12356.1 - 0.032 12.5 16.4 0.042 12.1 16.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KLO12356.1 - 0.4 8.9 11.1 0.55 8.5 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KLO12356.1 - 1.3 7.0 20.8 1.9 6.5 20.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KLO12356.1 - 1.5 8.1 20.1 2.4 7.4 20.1 1.2 1 0 0 1 1 1 0 NOA36 protein Tim54 PF11711.8 KLO12356.1 - 2 7.1 8.2 3.1 6.5 8.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 KLO12356.1 - 5.9 5.8 7.3 9.4 5.1 7.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 KLO12356.1 - 7 5.8 7.5 10 5.2 7.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 KLO12356.1 - 7 5.9 22.2 10 5.3 22.2 1.2 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 KLO12356.1 - 7.5 5.2 9.0 11 4.6 9.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Trypan_PARP PF05887.11 KLO12356.1 - 9.5 6.2 13.1 17 5.4 13.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) adh_short PF00106.25 KLO12358.1 - 2.4e-25 89.2 0.1 3.3e-25 88.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO12358.1 - 3.7e-19 69.2 0.0 4.8e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO12358.1 - 5.5e-05 23.2 0.0 0.00013 21.9 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KLO12358.1 - 0.0046 16.9 0.2 0.0089 15.9 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KLO12358.1 - 0.05 13.1 0.3 0.083 12.4 0.3 1.2 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 KLO12359.1 - 5e-23 81.6 0.1 6.6e-23 81.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO12359.1 - 1.7e-13 50.7 0.0 2.6e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO12359.1 - 0.00071 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KLO12359.1 - 0.019 14.6 0.3 0.032 13.8 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family ApbE PF02424.15 KLO12359.1 - 0.098 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 ApbE family adh_short PF00106.25 KLO12360.1 - 1.4e-27 96.4 0.5 1.9e-27 96.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO12360.1 - 1.5e-18 67.2 0.2 2.1e-18 66.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO12360.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KLO12360.1 - 0.018 14.9 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Methyltransf_15 PF09445.10 KLO12360.1 - 0.097 12.2 0.1 0.37 10.4 0.1 1.8 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MFS_1 PF07690.16 KLO12361.1 - 1.8e-45 155.4 48.9 1.8e-45 155.4 48.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO12361.1 - 6.6e-16 58.2 12.4 6.6e-16 58.2 12.4 3.7 4 0 0 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 KLO12361.1 - 3.1e-09 35.8 23.2 3.9e-09 35.5 23.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KLO12361.1 - 0.00026 20.0 8.2 0.00026 20.0 8.2 2.4 2 0 0 2 2 2 1 MFS_1 like family TMEM100 PF16311.5 KLO12361.1 - 0.19 11.3 2.1 2.7 7.6 0.0 3.0 3 0 0 3 3 3 0 Transmembrane protein 100 MFS_1 PF07690.16 KLO12362.1 - 2.6e-42 145.0 49.5 2.6e-42 145.0 49.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO12362.1 - 2.8e-14 52.8 10.7 2.8e-14 52.8 10.7 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KLO12362.1 - 3.5e-07 29.0 6.9 3.5e-07 29.0 6.9 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PhoD PF09423.10 KLO12363.1 - 3.6e-95 319.0 3.2 4.4e-95 318.7 3.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KLO12363.1 - 1.4e-23 83.3 0.0 3.3e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KLO12363.1 - 0.0031 18.0 4.3 0.0031 18.0 0.0 3.1 3 1 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Hydrophobin PF01185.18 KLO12364.1 - 3.5e-12 46.8 6.7 4.3e-12 46.5 6.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Aldolase_II PF00596.21 KLO12365.1 - 2.5e-37 128.6 0.0 3e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain bZIP_1 PF00170.21 KLO12367.1 - 2.9e-10 40.1 2.4 2.9e-10 40.1 2.4 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KLO12367.1 - 6.8e-06 26.1 6.6 6.8e-06 26.1 6.6 2.3 2 0 0 2 2 2 1 Basic region leucine zipper Macoilin PF09726.9 KLO12367.1 - 0.0032 16.1 4.3 0.0058 15.3 4.3 1.4 1 0 0 1 1 1 1 Macoilin family CENP-F_N PF10481.9 KLO12367.1 - 0.0036 17.0 0.6 0.0092 15.6 0.6 1.6 1 0 0 1 1 1 1 Cenp-F N-terminal domain NAM-associated PF14303.6 KLO12367.1 - 0.0043 17.8 1.2 0.046 14.4 0.0 2.8 2 1 1 3 3 3 1 No apical meristem-associated C-terminal domain ADIP PF11559.8 KLO12367.1 - 0.0098 16.0 7.0 0.017 15.2 7.0 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.9 KLO12367.1 - 0.082 11.7 0.7 0.13 11.0 0.7 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4472 PF14739.6 KLO12367.1 - 0.33 11.7 6.0 0.7 10.7 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) DivIC PF04977.15 KLO12367.1 - 2.2 8.1 8.6 15 5.5 0.2 2.3 1 1 1 2 2 2 0 Septum formation initiator bZIP_Maf PF03131.17 KLO12367.1 - 3.1 8.4 11.9 0.53 10.8 0.7 2.4 1 1 1 2 2 2 0 bZIP Maf transcription factor Peptidase_S10 PF00450.22 KLO12368.1 - 1.5e-87 294.7 0.2 1.8e-87 294.5 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase zf-MYND PF01753.18 KLO12369.1 - 7.7e-07 29.1 10.8 7.7e-07 29.1 10.8 2.1 2 0 0 2 2 2 1 MYND finger FN3_7 PF18447.1 KLO12369.1 - 0.14 12.4 1.3 0.29 11.4 1.3 1.4 1 0 0 1 1 1 0 Fibronectin type III domain zf-C6H2 PF15801.5 KLO12369.1 - 0.9 9.9 9.8 0.99 9.8 6.4 2.3 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Ribosomal_S26e PF01283.19 KLO12370.1 - 2.4e-52 175.9 10.4 3e-52 175.6 10.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.11 KLO12370.1 - 0.052 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Fer4_7 PF12838.7 KLO12370.1 - 0.14 12.7 3.4 4 8.1 1.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain TMF_TATA_bd PF12325.8 KLO12371.1 - 0.013 15.8 0.2 0.013 15.8 0.2 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SOAR PF16533.5 KLO12371.1 - 0.15 12.1 3.1 9.1 6.3 0.1 2.4 2 0 0 2 2 2 0 STIM1 Orai1-activating region Dpoe2NT PF12213.8 KLO12372.1 - 0.022 15.0 1.2 0.022 15.0 1.2 2.7 3 0 0 3 3 3 0 DNA polymerases epsilon N terminal RNA_polI_A14 PF08203.11 KLO12372.1 - 0.19 12.5 1.6 0.45 11.3 0.1 2.3 2 1 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 DUF3810 PF12725.7 KLO12372.1 - 0.27 10.6 4.1 0.54 9.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) FlgM PF04316.13 KLO12372.1 - 0.33 11.4 5.6 4.3 7.8 0.9 2.6 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM FliT PF05400.13 KLO12372.1 - 0.39 11.6 7.9 0.4 11.5 0.0 3.4 3 0 0 3 3 3 0 Flagellar protein FliT TBCC_N PF16752.5 KLO12372.1 - 0.47 10.9 10.0 0.56 10.7 0.7 3.3 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Fez1 PF06818.15 KLO12372.1 - 0.92 9.9 12.8 0.15 12.5 0.5 2.8 2 1 0 2 2 2 0 Fez1 Spc7 PF08317.11 KLO12372.1 - 1.8 7.4 17.1 0.054 12.4 2.8 2.9 2 1 0 2 2 2 0 Spc7 kinetochore protein ZapD PF07072.11 KLO12372.1 - 2.4 7.9 7.3 11 5.7 1.4 2.7 2 1 0 2 2 2 0 Cell division protein Mod_r PF07200.13 KLO12372.1 - 6.6 6.8 18.9 0.068 13.3 3.8 3.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Fib_alpha PF08702.10 KLO12373.1 - 2.7e-05 24.4 1.7 0.0013 18.9 0.3 2.2 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family Mitofilin PF09731.9 KLO12373.1 - 0.02 13.8 3.5 0.028 13.3 3.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Syntaxin-18_N PF10496.9 KLO12373.1 - 0.086 13.1 1.8 0.5 10.6 0.2 2.3 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Med9 PF07544.13 KLO12373.1 - 0.16 12.1 3.1 0.71 10.0 0.9 2.8 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FAM25 PF15825.5 KLO12373.1 - 0.34 11.3 4.0 1.1 9.7 0.5 2.5 2 1 0 2 2 2 0 FAM25 family GARP PF16731.5 KLO12373.1 - 0.4 10.3 4.3 9.3 5.9 0.6 2.4 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Jnk-SapK_ap_N PF09744.9 KLO12373.1 - 0.95 9.7 5.8 0.1 12.8 0.8 1.9 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF3347 PF11827.8 KLO12373.1 - 5 7.3 5.9 8.6 6.5 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) TMEM65 PF10507.9 KLO12374.1 - 0.022 14.7 0.1 0.032 14.2 0.1 1.3 1 1 0 1 1 1 0 Transmembrane protein 65 Spectrin PF00435.21 KLO12374.1 - 0.1 13.1 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 Spectrin repeat Ribosomal_S26e PF01283.19 KLO12375.1 - 9.6e-52 174.0 9.8 1.1e-51 173.7 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Ribosomal_S26e PF01283.19 KLO12376.1 - 2.5e-49 166.2 8.5 2.9e-49 166.0 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF4336 PF14234.6 KLO12377.1 - 2.7e-13 49.8 0.0 9.4e-10 38.2 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) SPX PF03105.19 KLO12379.1 - 1.5 8.7 20.3 2.3 8.0 20.3 1.3 1 0 0 1 1 1 0 SPX domain Hid1 PF12722.7 KLO12379.1 - 8.9 4.3 12.2 11 4.0 12.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NYN PF01936.18 KLO12380.1 - 1.2e-11 45.3 0.0 3.1e-11 44.0 0.0 1.6 2 0 0 2 2 2 1 NYN domain NYN PF01936.18 KLO12381.1 - 1e-07 32.5 0.0 1.8e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 NYN domain Chs7 PF12271.8 KLO12384.1 - 1.2e-81 274.3 3.1 1.5e-81 274.0 3.1 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Piwi PF02171.17 KLO12385.1 - 7.8e-74 248.6 0.0 1e-73 248.2 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 KLO12385.1 - 7.3e-18 64.0 0.7 6.6e-17 60.9 0.4 2.6 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoN PF16486.5 KLO12385.1 - 1.4e-15 58.2 0.0 2.3e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KLO12385.1 - 1.2e-11 44.5 0.0 2.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KLO12385.1 - 9.3e-10 38.7 0.0 2.8e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KLO12385.1 - 0.2 12.0 0.0 0.45 10.8 0.0 1.6 1 0 0 1 1 1 0 Mid domain of argonaute Piwi PF02171.17 KLO12386.1 - 1.9e-71 240.8 0.0 2.6e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KLO12386.1 - 3.4e-16 60.1 0.1 5.9e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KLO12386.1 - 1.2e-13 50.5 0.1 2.9e-13 49.2 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KLO12386.1 - 3.2e-09 36.7 0.0 8e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KLO12386.1 - 1.3e-08 35.1 0.0 4e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KLO12386.1 - 0.0012 19.1 0.0 0.0046 17.2 0.0 2.0 2 0 0 2 2 2 1 Mid domain of argonaute Glyco_hydro_1 PF00232.18 KLO12387.1 - 1.9e-154 514.4 0.1 2.3e-154 514.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DnaJ PF00226.31 KLO12388.1 - 2.9e-17 62.5 0.3 4.2e-17 62.0 0.3 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 KLO12388.1 - 4.7e-13 48.6 0.5 8.7e-13 47.8 0.5 1.5 1 0 0 1 1 1 1 CSL zinc finger Amidase PF01425.21 KLO12389.1 - 1.8e-30 106.3 3.0 3.9e-30 105.2 3.0 1.5 1 0 0 1 1 1 1 Amidase Glyco_hydro_1 PF00232.18 KLO12390.1 - 3.7e-146 487.1 0.4 4.3e-146 486.9 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cu-oxidase PF00394.22 KLO12391.1 - 4e-39 134.3 0.8 2.6e-33 115.4 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KLO12391.1 - 1.6e-37 128.3 3.5 3.7e-35 120.6 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KLO12391.1 - 3.1e-34 117.6 6.3 5.3e-31 107.1 0.1 4.0 5 0 0 5 5 5 2 Multicopper oxidase Peptidase_M30 PF10460.9 KLO12391.1 - 0.018 14.0 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase M30 Abhydrolase_3 PF07859.13 KLO12392.1 - 3.8e-13 49.8 0.0 6.2e-13 49.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KLO12392.1 - 1.8e-07 30.4 0.0 1.2e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KLO12392.1 - 2.1e-05 23.5 0.0 2.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KLO12392.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 NACHT PF05729.12 KLO12393.1 - 1e-08 35.3 0.1 9.9e-08 32.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KLO12393.1 - 1.2e-06 29.0 1.6 0.00072 20.0 0.1 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KLO12393.1 - 0.029 14.6 0.7 0.17 12.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KLO12393.1 - 0.057 14.0 0.0 0.26 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KLO12393.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Dynamin_N PF00350.23 KLO12396.1 - 8.6e-27 94.2 0.0 6.6e-26 91.4 0.0 2.5 3 1 0 3 3 3 1 Dynamin family Dynamin_M PF01031.20 KLO12396.1 - 1.6e-23 83.3 0.0 6.6e-23 81.3 0.0 1.9 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 KLO12396.1 - 5.2e-11 42.5 0.6 1.2e-10 41.3 0.6 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KLO12396.1 - 9.7e-05 22.4 0.0 0.00097 19.2 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KLO12396.1 - 0.024 14.9 1.1 0.13 12.5 0.2 2.8 3 0 0 3 3 3 0 AAA domain LcrR PF09621.10 KLO12397.1 - 0.11 12.0 0.1 0.42 10.1 0.1 1.8 2 0 0 2 2 2 0 Type III secretion system regulator (LcrR) P22_portal PF16510.5 KLO12398.1 - 0.44 9.1 1.6 6.6 5.2 0.3 2.1 2 0 0 2 2 2 0 Phage P22-like portal protein Dynamin_M PF01031.20 KLO12399.1 - 8.1e-27 94.2 0.0 1.1e-25 90.4 0.0 2.3 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KLO12399.1 - 5.8e-25 88.3 0.0 2.1e-24 86.5 0.0 2.0 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 KLO12399.1 - 3.7e-12 46.2 1.8 9.9e-12 44.9 1.8 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KLO12399.1 - 0.00028 21.0 0.1 0.0024 17.9 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Methyltransf_1N PF02870.15 KLO12399.1 - 0.066 14.0 0.0 0.17 12.7 0.0 1.7 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DUF423 PF04241.15 KLO12400.1 - 1.7 8.9 4.8 11 6.3 1.6 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF423) TraC_F_IV PF11130.8 KLO12412.1 - 0.046 13.3 1.8 1.9 8.1 0.1 2.4 1 1 1 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer Baculo_PEP_C PF04513.12 KLO12412.1 - 0.23 11.5 6.1 3.4 7.7 0.1 3.1 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus RP-C_C PF11800.8 KLO12412.1 - 1.2 9.2 5.6 0.43 10.6 1.9 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region DDHD PF02862.17 KLO12412.1 - 5.8 7.0 6.8 9.5 6.3 6.0 1.7 1 1 1 2 2 2 0 DDHD domain NACHT PF05729.12 KLO12413.1 - 4.7e-11 42.9 0.5 1.5e-10 41.3 0.5 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO12413.1 - 2.9e-07 31.0 0.1 4.3e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO12413.1 - 0.013 15.8 0.0 0.022 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KLO12413.1 - 0.017 15.1 0.0 6.8 6.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KLO12413.1 - 0.021 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase NB-ARC PF00931.22 KLO12413.1 - 0.036 13.3 0.0 0.099 11.8 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 KLO12413.1 - 0.039 13.8 0.1 0.061 13.2 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 KLO12413.1 - 0.043 14.2 0.0 0.089 13.2 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KLO12413.1 - 0.091 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 zf-MYND PF01753.18 KLO12414.1 - 2.6e-11 43.4 15.2 2.6e-11 43.4 15.2 2.4 3 0 0 3 3 3 1 MYND finger DUF1924 PF09086.11 KLO12414.1 - 0.016 15.6 2.1 0.045 14.1 2.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) Sucrose_synth PF00862.19 KLO12414.1 - 0.02 13.3 0.0 0.031 12.6 0.0 1.2 1 0 0 1 1 1 0 Sucrose synthase Ecl1 PF12855.7 KLO12414.1 - 0.1 13.8 0.2 0.17 13.0 0.2 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins zf-Mss51 PF13824.6 KLO12414.1 - 0.26 11.4 5.7 0.65 10.1 5.7 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KLO12414.1 - 2.7 8.4 12.4 8.8 6.7 12.4 1.9 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CFEM PF05730.11 KLO12418.1 - 2.4e-08 33.9 10.4 4e-08 33.2 10.4 1.3 1 0 0 1 1 1 1 CFEM domain CFEM PF05730.11 KLO12420.1 - 2e-08 34.2 14.6 3.6e-08 33.4 14.6 1.4 1 0 0 1 1 1 1 CFEM domain Podoplanin PF05808.11 KLO12420.1 - 1.1 9.3 7.8 1.8 8.6 7.8 1.4 1 1 0 1 1 1 0 Podoplanin UPF0126 PF03458.13 KLO12420.1 - 2.4 8.1 9.1 0.55 10.2 5.4 1.9 2 0 0 2 2 2 0 UPF0126 domain SPX PF03105.19 KLO12420.1 - 4.6 7.1 6.4 5.6 6.8 6.4 1.0 1 0 0 1 1 1 0 SPX domain CFEM PF05730.11 KLO12424.1 - 1.4e-08 34.7 14.1 2.1e-08 34.1 14.1 1.3 1 0 0 1 1 1 1 CFEM domain zf-MYND PF01753.18 KLO12425.1 - 1.4e-10 41.0 15.2 2.9e-10 40.1 15.2 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO12425.1 - 2 8.6 6.0 4.5 7.5 6.0 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2955 PF11168.8 KLO12426.1 - 0.046 13.6 0.2 0.058 13.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) AAA_16 PF13191.6 KLO12427.1 - 5.5e-07 30.1 0.1 0.0014 19.0 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 KLO12427.1 - 6.7e-07 29.4 0.0 2.4e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KLO12427.1 - 0.003 18.0 0.0 0.014 15.8 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_20 PF12840.7 KLO12427.1 - 0.014 15.4 0.1 0.044 13.8 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_18 PF13238.6 KLO12427.1 - 0.015 15.8 0.0 0.084 13.4 0.0 2.4 2 0 0 2 2 1 0 AAA domain MarR_2 PF12802.7 KLO12427.1 - 0.05 13.5 0.4 0.13 12.2 0.4 1.7 1 0 0 1 1 1 0 MarR family AAA_30 PF13604.6 KLO12427.1 - 0.052 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KLO12427.1 - 0.054 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 KLO12427.1 - 0.061 13.2 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 KLO12427.1 - 0.076 13.3 0.0 0.48 10.7 0.0 2.4 1 0 0 1 1 1 0 AAA domain HTH_15 PF12324.8 KLO12427.1 - 0.091 12.7 0.3 2 8.4 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase PhoH PF02562.16 KLO12427.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein HTH_Crp_2 PF13545.6 KLO12427.1 - 0.13 12.3 0.0 0.45 10.5 0.0 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TFIIE_beta PF02186.15 KLO12427.1 - 0.22 11.8 0.8 2.2 8.7 0.0 3.2 4 0 0 4 4 2 0 TFIIE beta subunit core domain AAA_16 PF13191.6 KLO12430.1 - 1.1e-08 35.6 2.0 7.5e-06 26.4 0.1 3.7 4 0 0 4 4 4 2 AAA ATPase domain NACHT PF05729.12 KLO12430.1 - 2e-06 27.8 0.1 5.3e-06 26.4 0.1 1.7 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KLO12430.1 - 0.0062 17.0 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO12430.1 - 0.025 14.9 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KLO12430.1 - 0.037 13.7 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KLO12430.1 - 0.057 14.0 0.0 0.21 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KLO12430.1 - 0.099 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KLO12430.1 - 0.13 11.4 0.0 0.45 9.6 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Plasmid_RAQPRD PF09686.10 KLO12430.1 - 0.16 12.2 0.5 0.55 10.5 0.1 2.1 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) VirB3 PF05101.13 KLO12431.1 - 4.3 7.6 7.1 0.81 10.0 1.5 2.5 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein F-box-like PF12937.7 KLO12432.1 - 2.3e-06 27.4 0.1 5.1e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like PHB_acc_N PF07879.11 KLO12432.1 - 0.022 14.8 0.0 1.8 8.7 0.0 2.8 2 1 1 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain Patatin PF01734.22 KLO12433.1 - 0.13 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Patatin-like phospholipase Tir_receptor_C PF07489.11 KLO12433.1 - 0.28 11.1 6.9 0.44 10.5 6.9 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SpvB PF03534.13 KLO12437.1 - 2.5e-12 46.6 4.3 4.7e-10 39.1 3.0 2.8 1 1 1 2 2 2 1 Salmonella virulence plasmid 65kDa B protein Helicase_C PF00271.31 KLO12440.1 - 2.4e-09 37.5 0.0 9.1e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO12440.1 - 3.8e-09 36.5 0.0 6.8e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase STI1 PF17830.1 KLO12440.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 STI1 domain Protoglobin PF11563.8 KLO12440.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Protoglobin Mito_carr PF00153.27 KLO12442.1 - 4.9e-51 170.6 0.3 5e-16 58.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3262 PF11660.8 KLO12444.1 - 4.5 7.7 7.5 0.72 10.3 1.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) SseC PF04888.12 KLO12446.1 - 0.002 17.8 0.1 0.0037 16.9 0.1 1.4 1 1 1 2 2 2 1 Secretion system effector C (SseC) like family Baculo_PEP_C PF04513.12 KLO12446.1 - 0.024 14.7 1.3 0.052 13.6 0.4 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dicistro_VP4 PF11492.8 KLO12446.1 - 2.7 8.0 5.8 24 5.0 0.7 3.6 4 1 0 4 4 4 0 Cricket paralysis virus, VP4 DUF2335 PF10097.9 KLO12450.1 - 0.00088 19.2 0.1 0.0033 17.4 0.1 2.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2335) NPV_P10 PF05531.12 KLO12451.1 - 0.00059 20.2 8.2 0.0012 19.3 6.8 2.2 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KLO12451.1 - 0.0021 18.1 3.8 0.0075 16.3 3.6 2.0 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 KLO12451.1 - 0.0074 16.4 2.5 0.043 13.9 1.0 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2730) Apolipoprotein PF01442.18 KLO12451.1 - 0.0088 15.9 0.6 0.018 14.9 0.6 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Laminin_II PF06009.12 KLO12451.1 - 0.017 15.2 4.4 0.052 13.6 3.3 2.4 2 1 1 3 3 3 0 Laminin Domain II DUF4795 PF16043.5 KLO12451.1 - 0.026 14.2 0.9 0.053 13.1 0.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Tex_N PF09371.10 KLO12451.1 - 0.037 13.7 1.1 0.17 11.6 0.9 1.9 1 1 1 2 2 2 0 Tex-like protein N-terminal domain DHC_N2 PF08393.13 KLO12451.1 - 0.042 13.0 0.1 0.058 12.5 0.1 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 DUF1679 PF07914.11 KLO12451.1 - 0.051 12.4 0.3 0.068 12.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) SlyX PF04102.12 KLO12451.1 - 0.053 14.1 1.2 0.17 12.5 1.1 2.0 1 1 0 1 1 1 0 SlyX Phasin PF05597.11 KLO12451.1 - 0.054 13.5 3.0 0.1 12.6 2.6 1.7 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 KLO12451.1 - 0.068 13.2 3.1 0.17 11.9 1.8 2.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) HSBP1 PF06825.12 KLO12451.1 - 0.076 12.9 1.5 1.8 8.5 0.7 3.2 2 1 0 2 2 2 0 Heat shock factor binding protein 1 DUF948 PF06103.11 KLO12451.1 - 0.094 13.0 5.5 0.2 12.0 3.2 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1542 PF07564.11 KLO12451.1 - 0.11 12.6 5.0 0.16 12.1 3.5 1.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) LUC7 PF03194.15 KLO12451.1 - 0.12 12.0 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 LUC7 N_terminus AAA_13 PF13166.6 KLO12451.1 - 0.12 11.0 1.1 0.16 10.5 1.1 1.2 1 0 0 1 1 1 0 AAA domain KxDL PF10241.9 KLO12451.1 - 0.13 12.6 0.1 5.3 7.4 0.0 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein Prominin PF05478.11 KLO12451.1 - 0.14 10.1 0.7 0.17 9.8 0.7 1.1 1 0 0 1 1 1 0 Prominin BLOC1_2 PF10046.9 KLO12451.1 - 0.17 12.2 3.5 0.54 10.6 2.5 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin_2 PF14523.6 KLO12451.1 - 0.18 12.2 2.8 1.3 9.4 0.9 2.4 1 1 1 2 2 2 0 Syntaxin-like protein DUF4559 PF15112.6 KLO12451.1 - 0.22 11.2 1.7 0.27 10.9 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) DUF5370 PF17340.2 KLO12451.1 - 0.38 10.7 1.2 2.2 8.2 0.3 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5370) DEK_C PF08766.11 KLO12451.1 - 1.3 9.1 4.5 5.1 7.1 0.5 3.4 3 1 0 4 4 4 0 DEK C terminal domain PKcGMP_CC PF16808.5 KLO12451.1 - 1.7 8.6 4.2 4.4 7.2 0.5 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Osmo_CC PF08946.10 KLO12451.1 - 2.9 8.2 10.2 95 3.4 6.4 3.8 2 1 2 4 4 4 0 Osmosensory transporter coiled coil VHS PF00790.19 KLO12452.1 - 2.5e-29 102.0 0.1 1.2e-28 99.8 0.0 2.1 2 1 0 2 2 2 1 VHS domain GAT PF03127.14 KLO12452.1 - 2.7e-20 72.4 2.0 1.3e-19 70.3 0.1 2.4 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KLO12452.1 - 0.0032 17.0 0.2 0.012 15.2 0.2 2.0 1 0 0 1 1 1 1 GGA N-GAT domain Metallophos_3 PF14582.6 KLO12452.1 - 0.038 13.3 0.1 0.25 10.6 0.0 2.3 2 1 1 3 3 3 0 Metallophosphoesterase, calcineurin superfamily WYL_3 PF18488.1 KLO12452.1 - 0.11 12.9 0.1 39 4.7 0.0 3.1 2 0 0 2 2 2 0 WYL domain PTH2 PF01981.16 KLO12452.1 - 0.11 12.7 0.0 0.43 10.9 0.0 2.0 1 1 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 HR1 PF02185.16 KLO12452.1 - 1.4 9.1 7.0 0.42 10.8 0.9 2.5 2 0 0 2 2 2 0 Hr1 repeat NAT PF04768.13 KLO12453.1 - 4.6e-38 130.6 0.0 3.3e-27 95.2 0.0 2.3 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KLO12453.1 - 2.4e-26 92.5 0.0 5.3e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KLO12453.1 - 7.7e-26 91.2 0.1 1.7e-25 90.1 0.1 1.6 1 0 0 1 1 1 1 Amino acid kinase family FAM184 PF15665.5 KLO12454.1 - 0.00039 20.3 2.5 0.00039 20.3 2.5 1.9 2 0 0 2 2 2 1 Family with sequence similarity 184, A and B Lectin_N PF03954.14 KLO12454.1 - 0.047 13.4 0.7 0.11 12.2 0.7 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF2524 PF10732.9 KLO12454.1 - 0.13 12.6 6.2 1.7 9.0 0.8 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2524) Ax_dynein_light PF10211.9 KLO12455.1 - 0.033 14.1 0.5 0.074 13.0 0.5 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain IMD PF08397.11 KLO12456.1 - 0.084 12.2 3.5 0.1 11.9 0.5 2.1 2 0 0 2 2 2 0 IRSp53/MIM homology domain SpoOE-like PF09388.10 KLO12456.1 - 0.17 11.8 0.6 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein DGF-1_C PF11040.8 KLO12457.1 - 0.095 12.7 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Catalase PF00199.19 KLO12458.1 - 2.8e-188 625.8 0.1 3.5e-188 625.5 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KLO12458.1 - 2.8e-16 59.4 0.0 6.5e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive RA PF00788.23 KLO12459.1 - 6.8e-12 45.9 2.0 6.3e-10 39.6 0.0 4.2 4 1 0 4 4 4 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 KLO12459.1 - 5.8e-06 25.8 0.0 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KLO12459.1 - 0.0014 18.4 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain F-box PF00646.33 KLO12460.1 - 1.7e-05 24.5 0.7 4.4e-05 23.2 0.7 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO12460.1 - 7.3e-05 22.6 1.4 0.00013 21.7 0.2 2.1 2 0 0 2 2 2 1 F-box-like RRM_1 PF00076.22 KLO12461.1 - 2e-14 53.2 0.0 3.2e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KLO12461.1 - 0.0042 16.7 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KLO12461.1 - 0.0068 16.3 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 RL domain Hydrophobin PF01185.18 KLO12462.1 - 7e-17 61.8 9.1 8.8e-17 61.5 9.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin PI3_PI4_kinase PF00454.27 KLO12463.1 - 0.15 11.8 0.3 0.26 11.1 0.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase ADAM17_MPD PF16698.5 KLO12464.1 - 0.023 15.1 5.9 0.023 15.1 5.9 2.2 3 0 0 3 3 3 0 Membrane-proximal domain, switch, for ADAM17 DUF4349 PF14257.6 KLO12469.1 - 0.0046 16.4 2.5 0.0046 16.4 2.5 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4349) DUF3573 PF12097.8 KLO12469.1 - 0.015 14.2 0.1 0.018 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Baculo_PEP_C PF04513.12 KLO12469.1 - 0.059 13.4 13.8 8.4 6.4 3.6 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2673 PF10880.8 KLO12469.1 - 0.064 13.4 0.6 0.1 12.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) DUF1700 PF08006.11 KLO12469.1 - 0.076 12.5 3.4 0.11 12.1 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) FlxA PF14282.6 KLO12469.1 - 0.09 12.8 3.4 0.13 12.3 3.4 1.2 1 0 0 1 1 1 0 FlxA-like protein AI-2E_transport PF01594.16 KLO12469.1 - 0.44 9.7 10.1 0.61 9.2 4.5 2.1 1 1 1 2 2 2 0 AI-2E family transporter Baculo_PEP_C PF04513.12 KLO12471.1 - 0.00076 19.5 10.2 0.034 14.2 2.2 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1700 PF08006.11 KLO12471.1 - 0.013 15.1 3.2 0.019 14.5 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) TetR_C_6 PF13977.6 KLO12471.1 - 0.86 9.8 3.4 4.3 7.6 0.5 2.5 2 1 1 3 3 3 0 BetI-type transcriptional repressor, C-terminal DUF4349 PF14257.6 KLO12471.1 - 3 7.2 8.5 0.27 10.7 2.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) ERCC4 PF02732.15 KLO12474.1 - 1e-19 71.2 0.0 2e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 KLO12474.1 - 0.0049 17.4 0.1 0.014 16.0 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain MFS_1 PF07690.16 KLO12475.1 - 3e-19 69.2 53.6 1.6e-13 50.4 32.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 KLO12478.1 - 7.3e-09 36.1 0.1 0.012 16.5 0.0 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.7 KLO12478.1 - 4e-08 33.0 2.9 7.4e-07 29.0 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO12478.1 - 5.1e-05 23.0 1.1 0.00064 19.5 0.1 2.4 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KLO12478.1 - 0.0066 16.7 0.0 4.9 7.5 0.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Elongin_A PF06881.11 KLO12478.1 - 0.021 15.3 0.3 0.081 13.5 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Beach PF02138.18 KLO12479.1 - 1.1e-104 349.7 0.0 2e-104 348.8 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 KLO12479.1 - 6.3e-09 36.2 0.1 1.4e-08 35.0 0.1 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 KLO12479.1 - 1.5e-07 31.4 0.0 4.8e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KLO12479.1 - 0.0001 23.0 9.4 0.55 11.2 0.3 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF4704 PF15787.5 KLO12479.1 - 0.11 11.7 0.1 13 4.9 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4704) FHA PF00498.26 KLO12480.1 - 3.3e-15 56.2 0.0 7.7e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KLO12480.1 - 4.3e-09 36.0 14.0 7.6e-09 35.2 14.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KLO12480.1 - 7.8e-07 29.3 13.7 1.2e-06 28.7 13.7 1.3 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 KLO12480.1 - 0.0015 18.8 0.0 0.0083 16.4 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 KLO12480.1 - 0.0032 17.3 14.7 0.0052 16.6 14.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO12480.1 - 0.0083 16.0 6.7 0.015 15.1 6.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KLO12480.1 - 0.02 14.9 5.0 0.036 14.1 5.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KLO12480.1 - 0.027 14.8 8.4 0.055 13.8 8.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KLO12480.1 - 0.031 14.3 11.8 0.056 13.4 11.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KLO12480.1 - 0.047 13.6 12.8 0.08 12.8 12.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO12480.1 - 1.8 8.5 10.9 3.2 7.7 10.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KLO12480.1 - 5.2 6.8 9.2 9.1 6.0 9.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Peptidase_S41 PF03572.18 KLO12481.1 - 0.0012 18.4 0.0 0.0032 17.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 DUF1308 PF07000.11 KLO12482.1 - 2.2e-08 34.2 0.1 0.0013 18.7 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF1308) SPC12 PF06645.13 KLO12484.1 - 1e-25 89.6 0.3 1.2e-25 89.3 0.3 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) S1-P1_nuclease PF02265.16 KLO12485.1 - 6.9e-62 209.5 0.0 1.7e-60 204.9 0.0 2.0 1 1 0 1 1 1 1 S1/P1 Nuclease zf-rbx1 PF12678.7 KLO12487.1 - 1.6e-24 85.9 13.4 2.3e-24 85.4 13.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KLO12487.1 - 2.6e-17 62.7 9.7 3.5e-17 62.2 9.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KLO12487.1 - 1.7e-06 28.2 14.4 5.9e-05 23.3 14.4 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KLO12487.1 - 0.00084 19.2 12.0 0.02 14.7 12.0 2.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO12487.1 - 0.0011 18.7 14.6 0.063 13.1 14.6 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KLO12487.1 - 0.0035 17.1 2.7 0.0035 17.1 2.7 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KLO12487.1 - 0.094 12.6 10.8 0.26 11.2 4.4 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO12487.1 - 0.26 11.3 7.3 0.9 9.6 7.3 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KLO12487.1 - 0.31 10.7 14.1 0.059 13.0 4.2 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KLO12487.1 - 1.1 9.5 10.0 7.1 6.9 10.1 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain TBCC PF07986.12 KLO12488.1 - 1.1e-18 67.1 0.5 2.7e-18 65.8 0.4 1.8 1 1 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KLO12488.1 - 3.3e-13 50.1 1.0 5.4e-13 49.4 1.0 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain KfrA_N PF11740.8 KLO12488.1 - 0.0093 16.6 0.1 0.015 15.9 0.1 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term DUF4482 PF14818.6 KLO12488.1 - 0.12 13.3 0.2 0.2 12.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) HMGL-like PF00682.19 KLO12489.1 - 1.2e-42 146.3 0.0 2.2e-42 145.5 0.0 1.4 1 1 0 1 1 1 1 HMGL-like SKG6 PF08693.10 KLO12490.1 - 0.0035 16.7 0.1 0.0079 15.6 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KLO12490.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Oxidored_q3 PF00499.20 KLO12490.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 TMEM154 PF15102.6 KLO12490.1 - 0.59 10.0 0.0 0.59 10.0 0.0 3.4 4 0 0 4 4 4 0 TMEM154 protein family Abhydrolase_6 PF12697.7 KLO12491.1 - 7.4e-12 46.3 1.0 1.4e-11 45.5 1.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO12491.1 - 6.4e-05 22.7 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KLO12491.1 - 0.00016 21.3 0.0 0.00057 19.4 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KLO12491.1 - 0.00049 19.5 0.0 0.0036 16.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 KLO12491.1 - 0.0042 15.7 0.0 0.006 15.1 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 KLO12491.1 - 0.029 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Dot_icm_IcmQ PF09475.10 KLO12491.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Metallophos PF00149.28 KLO12492.1 - 4.5e-14 53.4 1.8 7.6e-14 52.7 1.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KLO12492.1 - 0.064 13.5 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain DUF4106 PF13388.6 KLO12492.1 - 6.3 5.9 5.5 12 5.0 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4106) DUF775 PF05603.12 KLO12493.1 - 1.3e-53 181.5 0.0 1.5e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) SET PF00856.28 KLO12494.1 - 1.6e-17 64.4 1.5 5.6e-17 62.6 0.1 2.8 3 1 0 3 3 3 1 SET domain RRM_1 PF00076.22 KLO12494.1 - 1e-08 34.9 0.0 1.6e-06 27.9 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) N-SET PF11764.8 KLO12494.1 - 1.4e-06 28.5 6.0 1.4e-06 28.5 6.0 4.8 5 1 0 5 5 5 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KLO12494.1 - 1.6e-06 27.7 0.0 7.1e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated ABC_tran PF00005.27 KLO12495.1 - 6.2e-22 78.6 0.0 1.4e-21 77.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KLO12495.1 - 9e-06 25.3 0.2 0.12 11.8 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KLO12495.1 - 1.7e-05 24.8 0.2 0.017 15.0 0.1 2.6 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KLO12495.1 - 0.0074 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KLO12495.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KLO12495.1 - 0.076 13.4 0.0 0.27 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KLO12495.1 - 0.092 12.5 0.0 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KLO12495.1 - 0.097 12.9 0.0 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KLO12495.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KLO12495.1 - 0.26 11.8 1.0 0.53 10.8 0.1 1.9 2 1 0 2 2 2 0 AAA domain Ebola_NP PF05505.12 KLO12498.1 - 5.1 5.3 9.4 5.7 5.1 9.4 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein CPDase PF07823.11 KLO12499.1 - 1.2e-14 54.5 1.1 3.8e-11 43.1 0.0 2.1 1 1 0 2 2 2 2 Cyclic phosphodiesterase-like protein LigT_PEase PF02834.16 KLO12499.1 - 0.0063 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 KLO12499.1 - 0.018 14.9 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily tRNA_lig_CPD PF08302.11 KLO12499.1 - 0.048 13.1 0.0 0.77 9.1 0.0 2.1 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain Ras PF00071.22 KLO12500.1 - 1.1e-52 177.9 0.0 1.3e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO12500.1 - 1.9e-22 79.7 0.0 2.7e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO12500.1 - 1.6e-07 31.0 0.0 4e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KLO12500.1 - 0.0086 15.5 0.0 0.0099 15.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KLO12500.1 - 0.012 15.5 0.0 0.9 9.4 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KLO12500.1 - 0.19 12.1 0.0 0.3 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KLO12500.1 - 0.2 11.0 0.0 0.27 10.7 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Bestrophin PF01062.21 KLO12501.1 - 1.5e-32 113.2 0.3 4.3e-17 62.4 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel tRNA-synt_2b PF00587.25 KLO12502.1 - 4.9e-37 127.6 0.0 3.1e-36 125.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KLO12502.1 - 3.3e-15 56.2 8.0 6e-15 55.4 8.0 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CARD PF00619.21 KLO12502.1 - 0.073 13.1 0.3 3.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Caspase recruitment domain TssO PF17561.2 KLO12502.1 - 0.23 11.5 5.0 0.47 10.6 5.0 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssO SPT16 PF08644.11 KLO12502.1 - 0.27 11.4 2.6 0.47 10.6 2.6 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) WD40 PF00400.32 KLO12503.1 - 9.6e-06 26.2 9.1 0.19 12.6 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat PSII_BNR PF14870.6 KLO12503.1 - 0.0028 17.0 0.0 0.009 15.3 0.0 1.8 2 0 0 2 2 2 1 Photosynthesis system II assembly factor YCF48 WD40_like PF17005.5 KLO12503.1 - 0.033 13.5 0.1 0.063 12.6 0.1 1.5 1 0 0 1 1 1 0 WD40-like domain ANAPC4_WD40 PF12894.7 KLO12503.1 - 0.04 14.2 0.1 43 4.5 0.0 3.6 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain RR_TM4-6 PF06459.12 KLO12503.1 - 0.17 11.7 8.6 0.3 10.9 8.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KLO12503.1 - 0.21 9.8 17.0 0.3 9.3 17.0 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KLO12503.1 - 0.27 10.6 19.6 0.36 10.1 19.6 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 KLO12503.1 - 2.1 6.7 22.2 2.9 6.3 22.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 KLO12503.1 - 2.2 6.4 21.9 2.9 6.0 21.9 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 KLO12503.1 - 3.3 6.1 13.1 4.6 5.7 13.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Merozoite_SPAM PF07133.11 KLO12503.1 - 9.2 6.2 25.8 17 5.4 25.8 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) STAG PF08514.11 KLO12504.1 - 2.6e-36 124.0 0.2 2.6e-36 124.0 0.2 2.6 3 0 0 3 3 3 1 STAG domain HEAT_2 PF13646.6 KLO12504.1 - 2.7e-06 27.6 0.0 0.034 14.5 0.0 3.6 2 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KLO12504.1 - 0.00098 19.2 3.9 25 5.5 0.0 6.1 7 0 0 7 7 7 1 HEAT repeat HBB PF06777.11 KLO12504.1 - 0.078 12.6 1.3 1.3 8.6 0.1 2.6 2 0 0 2 2 2 0 Helical and beta-bridge domain Ribonuc_2-5A PF06479.12 KLO12505.1 - 3.2e-45 153.4 0.1 5.6e-45 152.6 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KLO12505.1 - 5.9e-41 140.6 0.0 1.5e-38 132.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12505.1 - 1.1e-23 83.9 0.0 1.1e-22 80.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO12505.1 - 6.9e-05 21.8 0.0 0.00026 19.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase PQQ PF01011.21 KLO12505.1 - 0.00042 20.1 0.0 0.01 15.7 0.0 2.9 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.14 KLO12505.1 - 0.012 15.0 0.0 0.033 13.5 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short_C2 PF13561.6 KLO12506.1 - 8e-57 192.5 1.9 1.1e-56 192.1 1.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO12506.1 - 1.8e-32 112.4 0.9 2.7e-32 111.8 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO12506.1 - 0.00087 19.3 0.4 0.0013 18.7 0.4 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KLO12506.1 - 0.015 15.2 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CBP_BcsN PF17038.5 KLO12506.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN Aldedh PF00171.22 KLO12507.1 - 1.8e-124 415.8 0.0 2.1e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.32 KLO12508.1 - 1.5e-41 139.6 23.9 2.1e-08 34.7 0.0 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO12508.1 - 6.9e-12 45.5 0.3 0.0061 16.8 0.0 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KLO12508.1 - 3.4e-10 39.7 0.5 6.3e-10 38.8 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO12508.1 - 2.4e-07 30.5 0.3 4.5e-07 29.6 0.3 1.5 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KLO12508.1 - 2.6e-05 23.7 0.1 0.0052 16.2 0.0 3.1 2 1 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 KLO12508.1 - 6.7e-05 21.7 0.9 1.5 7.4 0.1 4.7 3 1 1 4 4 4 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KLO12508.1 - 0.001 19.0 0.0 3.5 7.7 0.0 4.1 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 KLO12508.1 - 0.022 13.7 0.2 0.45 9.4 0.1 3.1 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 KLO12508.1 - 0.052 13.1 0.1 1 8.9 0.0 2.4 1 1 1 2 2 2 0 PQQ-like domain Nucleoporin_N PF08801.11 KLO12508.1 - 0.057 12.2 0.2 8 5.1 0.0 3.4 3 1 0 4 4 4 0 Nup133 N terminal like ZapB PF06005.12 KLO12509.1 - 0.29 11.6 0.9 1.5 9.3 0.2 2.2 2 0 0 2 2 2 0 Cell division protein ZapB WD40 PF00400.32 KLO12510.1 - 1.9e-24 85.5 19.9 7.5e-06 26.6 0.2 7.1 8 0 0 8 8 8 6 WD domain, G-beta repeat WD40_like PF17005.5 KLO12510.1 - 0.002 17.5 0.0 3.3 7.0 0.0 3.1 3 0 0 3 3 3 3 WD40-like domain ANAPC4_WD40 PF12894.7 KLO12510.1 - 0.04 14.2 0.0 2.6 8.4 0.0 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain UPF0139 PF03669.13 KLO12511.1 - 9.1e-05 22.3 0.0 0.00012 21.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) F-box-like PF12937.7 KLO12512.1 - 3.3e-08 33.3 4.9 4.3e-07 29.7 4.9 2.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO12512.1 - 0.34 10.9 6.4 0.47 10.4 0.2 2.8 3 0 0 3 3 3 0 F-box domain ABC_tran PF00005.27 KLO12514.1 - 1.3e-21 77.6 0.0 2.4e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KLO12514.1 - 1.6e-05 24.4 3.4 0.051 13.0 0.2 2.7 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KLO12514.1 - 1.7e-05 24.8 0.3 0.0037 17.1 0.2 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KLO12514.1 - 0.00087 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KLO12514.1 - 0.0071 16.1 0.1 0.021 14.6 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KLO12514.1 - 0.035 14.6 0.0 0.093 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KLO12514.1 - 0.051 13.9 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KLO12514.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KLO12514.1 - 0.062 13.7 0.1 0.17 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KLO12514.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.6 KLO12514.1 - 0.15 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 KLO12515.1 - 0.0018 18.1 2.9 0.0083 16.0 2.9 2.2 1 1 0 1 1 1 1 F-box-like 4HBT PF03061.22 KLO12516.1 - 3.5e-10 40.1 0.0 7.3e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KLO12516.1 - 0.00026 21.4 0.0 0.00031 21.1 0.0 1.2 1 1 0 1 1 1 1 Thioesterase-like superfamily MFS_1 PF07690.16 KLO12517.1 - 8.1e-25 87.5 30.0 8.1e-25 87.5 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KLO12517.1 - 2.7e-07 30.2 4.3 2.7e-07 30.2 4.3 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB H_PPase PF03030.16 KLO12517.1 - 0.028 13.1 0.2 0.078 11.6 0.0 1.8 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase ETF_QO PF05187.13 KLO12518.1 - 2.3e-37 127.3 0.0 3.9e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KLO12518.1 - 8.4e-08 32.2 0.9 1.6e-05 24.7 0.4 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO12518.1 - 1e-07 32.1 0.0 4.1e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO12518.1 - 1.2e-05 24.7 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO12518.1 - 2.6e-05 23.6 0.0 0.00063 19.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KLO12518.1 - 0.00011 21.1 0.5 0.00023 20.0 0.5 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KLO12518.1 - 0.00011 21.6 0.2 0.00018 20.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KLO12518.1 - 0.00013 22.0 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KLO12518.1 - 0.00019 20.6 1.2 0.00041 19.6 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KLO12518.1 - 0.0009 18.6 0.4 0.0013 18.0 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KLO12518.1 - 0.0025 17.2 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KLO12518.1 - 0.005 15.7 0.2 0.011 14.6 0.2 1.6 1 0 0 1 1 1 1 Tryptophan halogenase Fer4_7 PF12838.7 KLO12518.1 - 0.0075 16.8 0.2 0.026 15.1 0.3 1.9 2 0 0 2 2 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 KLO12518.1 - 0.013 14.6 0.2 0.019 14.0 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 KLO12518.1 - 0.026 15.1 0.2 1.7 9.3 0.3 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KLO12518.1 - 0.083 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KLO12518.1 - 0.089 11.9 0.3 0.19 10.7 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.6 KLO12518.1 - 0.096 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KLO12518.1 - 0.14 11.4 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_6 PF12837.7 KLO12518.1 - 1.6 8.9 4.4 1.4 9.2 1.0 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 KLO12518.1 - 2.8 8.2 3.9 0.66 10.2 0.4 1.8 2 0 0 2 2 1 0 4Fe-4S binding domain Fer2 PF00111.27 KLO12519.1 - 5.5e-11 42.3 0.0 7.5e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 KLO12519.1 - 0.07 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Magnetochrome domain Adap_comp_sub PF00928.21 KLO12520.1 - 1.9e-93 312.7 0.0 3.8e-93 311.7 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KLO12520.1 - 4.4e-06 26.7 0.2 7.8e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KLO12520.1 - 0.0088 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Formyl_trans_N PF00551.19 KLO12521.1 - 3.5e-36 124.6 0.0 5.8e-17 62.0 0.0 2.0 2 0 0 2 2 2 2 Formyl transferase Defensin_propep PF00879.18 KLO12522.1 - 0.086 13.1 0.2 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 Defensin propeptide Spo7 PF03907.13 KLO12523.1 - 1.1e-41 142.7 0.2 1.9e-41 142.0 0.2 1.3 1 0 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.9 KLO12523.1 - 0.0012 19.2 0.1 0.0024 18.3 0.1 1.4 1 1 0 1 1 1 1 Transmembrane protein 188 PHP PF02811.19 KLO12524.1 - 3.5e-12 46.9 0.4 6.9e-12 46.0 0.4 1.3 1 1 0 1 1 1 1 PHP domain Rnk_N PF14760.6 KLO12524.1 - 0.0079 16.7 0.3 0.0079 16.7 0.3 2.4 3 0 0 3 3 3 1 Rnk N-terminus DUF1327 PF07041.11 KLO12524.1 - 0.047 13.7 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1327) Archease PF01951.16 KLO12524.1 - 0.061 13.6 0.4 0.11 12.7 0.1 1.6 2 0 0 2 2 2 0 Archease protein family (MTH1598/TM1083) DUF1688 PF07958.11 KLO12526.1 - 1.8e-170 567.2 0.0 2e-170 567.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) MFS_2 PF13347.6 KLO12527.1 - 1.4e-08 33.7 13.8 1.4e-08 33.7 13.8 2.2 2 1 0 2 2 2 1 MFS/sugar transport protein Phytoreo_P8 PF07124.11 KLO12528.1 - 0.22 10.4 0.3 0.28 10.1 0.3 1.1 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 PQ-loop PF04193.14 KLO12529.1 - 4.1e-16 58.5 16.1 1.7e-09 37.3 0.5 3.4 3 1 1 4 4 4 2 PQ loop repeat His_Phos_2 PF00328.22 KLO12534.1 - 1.7e-46 159.3 0.0 2e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HCMV_UL124 PF17609.2 KLO12534.1 - 0.78 9.9 2.8 0.99 9.6 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function Fascin PF06268.13 KLO12535.1 - 0.0047 17.1 0.0 0.05 13.8 0.0 2.1 2 0 0 2 2 2 1 Fascin domain CFEM PF05730.11 KLO12540.1 - 3.5e-07 30.2 16.4 4.9e-07 29.7 16.4 1.2 1 0 0 1 1 1 1 CFEM domain Glyco_hydro_61 PF03443.14 KLO12541.1 - 1.1e-57 195.3 0.2 1.3e-57 195.1 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SurA_N_2 PF13623.6 KLO12542.1 - 0.073 12.9 0.3 9.4 6.1 0.0 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF4097 PF13349.6 KLO12542.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.3 1 1 0 1 1 1 0 Putative adhesin Tir_receptor_C PF07489.11 KLO12543.1 - 0.34 10.8 6.5 0.55 10.2 6.5 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus F-box-like PF12937.7 KLO12544.1 - 2.3e-08 33.8 0.1 6.1e-08 32.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like Myc_N PF01056.18 KLO12545.1 - 0.13 12.2 1.0 0.14 12.1 0.1 1.5 2 0 0 2 2 2 0 Myc amino-terminal region zf-MYND PF01753.18 KLO12546.1 - 4.6e-10 39.4 17.3 4.6e-10 39.4 17.3 2.3 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.7 KLO12546.1 - 0.011 17.0 0.4 0.022 15.9 0.4 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Fer4_24 PF18109.1 KLO12546.1 - 0.1 12.9 0.2 0.26 11.6 0.2 1.7 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain zf-C6H2 PF15801.5 KLO12546.1 - 2 8.8 12.9 6.4 7.2 12.9 1.9 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KLO12547.1 - 3.6e-09 36.6 13.2 3.6e-09 36.6 13.2 2.3 2 0 0 2 2 2 1 MYND finger F-box-like PF12937.7 KLO12548.1 - 1.8e-05 24.5 0.1 3.4e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like zf-MYND PF01753.18 KLO12549.1 - 1e-08 35.1 15.9 1e-08 35.1 15.9 2.4 3 0 0 3 3 3 1 MYND finger zf-Mss51 PF13824.6 KLO12549.1 - 0.36 11.0 5.2 0.84 9.8 5.2 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO12550.1 - 9.9e-11 41.6 12.2 1.5e-10 41.0 12.2 1.3 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 KLO12550.1 - 0.016 16.4 1.7 0.018 16.2 1.7 1.1 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins GH-E PF14410.6 KLO12550.1 - 0.073 13.5 0.1 0.092 13.2 0.1 1.2 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Zn_ribbon_17 PF17120.5 KLO12550.1 - 0.14 11.8 7.7 0.19 11.3 7.7 1.2 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-MYND PF01753.18 KLO12551.1 - 1.1e-10 41.4 11.7 1.1e-10 41.4 11.7 2.7 3 0 0 3 3 3 1 MYND finger F-box-like PF12937.7 KLO12553.1 - 4.1e-05 23.4 0.0 7.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO12554.1 - 7.2e-09 35.4 0.8 2.3e-08 33.8 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO12554.1 - 2.8e-07 30.3 0.8 7.6e-07 28.9 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KLO12556.1 - 7.5e-09 35.3 0.4 2.9e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO12556.1 - 9.6e-05 22.2 0.1 0.00027 20.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain Cerato-platanin PF07249.12 KLO12557.1 - 5.8e-43 145.8 0.4 6.7e-43 145.6 0.4 1.0 1 0 0 1 1 1 1 Cerato-platanin AdoHcyase_NAD PF00670.21 KLO12557.1 - 0.029 14.4 0.0 0.041 13.9 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DRIM PF07539.12 KLO12558.1 - 9e-156 519.8 2.0 9e-156 519.8 2.0 5.5 6 1 0 6 6 6 1 Down-regulated in metastasis MMS19_N PF14500.6 KLO12558.1 - 8.5e-06 25.5 11.1 0.038 13.6 3.3 5.7 5 1 0 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II Utp13 PF08625.11 KLO12558.1 - 0.0012 18.7 1.4 14 5.6 0.0 4.9 4 1 1 5 5 5 1 Utp13 specific WD40 associated domain HEAT PF02985.22 KLO12558.1 - 0.0018 18.4 3.1 12 6.4 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat RTP1_C1 PF10363.9 KLO12558.1 - 0.037 14.2 1.2 39 4.5 0.0 5.5 5 1 1 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KLO12558.1 - 0.041 12.4 9.6 0.54 8.7 0.0 4.9 5 1 0 5 5 5 0 Adaptin N terminal region CBF PF03914.17 KLO12558.1 - 0.05 13.6 0.1 0.62 10.1 0.0 2.9 2 0 0 2 2 2 0 CBF/Mak21 family DUF4042 PF13251.6 KLO12558.1 - 0.055 13.2 3.1 0.36 10.5 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) Condensin2nSMC PF12422.8 KLO12558.1 - 0.17 12.1 0.5 17 5.6 0.0 3.8 4 0 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit Xpo1 PF08389.12 KLO12558.1 - 0.31 11.1 8.8 20 5.3 0.0 5.7 6 1 0 6 6 6 0 Exportin 1-like protein Ceramidase_alk PF04734.13 KLO12559.1 - 1.5e-200 667.2 0.0 1.8e-200 666.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KLO12559.1 - 1.4e-54 184.5 0.0 2.4e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Cellulase PF00150.18 KLO12560.1 - 4.8e-07 29.5 0.0 8.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GRA6 PF05084.13 KLO12560.1 - 0.037 14.0 2.3 0.066 13.2 2.3 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) UCR_Fe-S_N PF10399.9 KLO12560.1 - 9.7 5.6 11.0 0.043 13.2 0.9 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TEA PF01285.18 KLO12563.1 - 7.7e-24 83.6 0.0 1.7e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Pinin_SDK_memA PF04696.13 KLO12565.1 - 8.3e-14 51.8 10.6 8.3e-14 51.8 10.6 3.2 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region Drf_GBD PF06371.13 KLO12565.1 - 0.089 12.3 1.9 0.16 11.5 1.9 1.3 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Vfa1 PF08432.10 KLO12565.1 - 2.8 8.3 13.7 1 9.7 2.8 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PRC2_HTH_1 PF18118.1 KLO12565.1 - 6.5 7.6 9.4 0.3 11.9 0.6 2.5 2 1 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain DUF1690 PF07956.11 KLO12565.1 - 9.4 6.6 15.6 5.6 7.4 6.2 2.2 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) HSP70 PF00012.20 KLO12567.1 - 0.0046 15.2 0.0 0.0071 14.6 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 KLO12567.1 - 0.03 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Tex_YqgF PF16921.5 KLO12568.1 - 0.98 9.9 3.9 0.48 10.9 0.1 2.3 3 0 0 3 3 3 0 Tex protein YqgF-like domain CorA PF01544.18 KLO12568.1 - 1.8 7.8 8.8 3.8 6.7 8.8 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CENP-K PF11802.8 KLO12568.1 - 4.3 6.8 14.4 1.5 8.3 1.3 2.3 2 0 0 2 2 2 0 Centromere-associated protein K Syntaxin-6_N PF09177.11 KLO12568.1 - 5.5 7.6 13.3 1.7 9.2 7.9 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Gcn1_N PF12074.8 KLO12569.1 - 7.6e-91 305.1 0.7 5.8e-90 302.2 0.1 3.0 3 0 0 3 3 3 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 KLO12569.1 - 5.3e-34 113.3 21.1 0.1 12.9 0.0 20.6 21 0 0 21 21 20 7 HEAT repeat HEAT_2 PF13646.6 KLO12569.1 - 1.8e-30 105.2 27.0 2.4e-06 27.8 0.1 14.2 9 4 7 16 16 16 7 HEAT repeats HEAT_EZ PF13513.6 KLO12569.1 - 3.7e-28 97.6 26.0 0.0011 19.5 0.0 17.0 13 4 7 20 20 20 8 HEAT-like repeat Cnd1 PF12717.7 KLO12569.1 - 3.6e-18 66.1 0.9 0.36 10.9 0.0 11.1 7 1 3 11 11 10 4 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KLO12569.1 - 4.3e-13 49.4 2.7 0.0001 21.9 0.0 8.8 7 1 3 11 11 11 2 CLASP N terminal IFRD PF05004.13 KLO12569.1 - 6.9e-08 32.0 5.4 0.0047 16.1 0.0 7.1 6 2 1 7 7 7 2 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 KLO12569.1 - 1.4e-07 32.0 0.0 1.3 9.6 0.0 7.2 7 1 1 8 8 6 1 Vacuolar 14 Fab1-binding region DUF3535 PF12054.8 KLO12569.1 - 1.1e-05 24.9 0.0 0.00082 18.7 0.0 3.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) ADSL_C PF10397.9 KLO12569.1 - 0.019 15.5 0.1 5.4 7.6 0.0 4.9 4 0 0 4 4 4 0 Adenylosuccinate lyase C-terminus Cohesin_HEAT PF12765.7 KLO12569.1 - 0.029 14.7 6.1 3 8.2 0.1 5.2 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion FANCI_S2 PF14676.6 KLO12569.1 - 0.034 14.5 4.3 1.3 9.4 0.3 5.1 5 0 0 5 5 5 0 FANCI solenoid 2 Phage_TAC_9 PF10876.8 KLO12569.1 - 0.14 12.2 0.1 1.4 9.0 0.0 2.8 3 0 0 3 3 2 0 Phage tail assemb.y chaperone protein, TAC HEAT_PBS PF03130.16 KLO12569.1 - 0.32 11.8 11.2 11 7.0 0.2 7.7 9 0 0 9 9 9 0 PBS lyase HEAT-like repeat S10_plectin PF03501.15 KLO12571.1 - 7.5e-40 134.9 0.0 8.9e-40 134.7 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain RQC PF09382.10 KLO12571.1 - 0.16 11.8 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 RQC domain F-box_4 PF15966.5 KLO12574.1 - 0.021 14.7 0.9 0.071 13.0 0.5 1.9 2 0 0 2 2 2 0 F-box F-box-like PF12937.7 KLO12574.1 - 0.087 12.7 0.9 0.18 11.8 0.9 1.5 1 0 0 1 1 1 0 F-box-like NAD_binding_5 PF07994.12 KLO12575.1 - 2.5e-138 460.9 0.0 2.9e-138 460.6 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KLO12575.1 - 3.4e-44 149.6 0.0 6.3e-44 148.7 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Helitron_like_N PF14214.6 KLO12577.1 - 6.5e-08 33.0 0.9 2e-07 31.5 0.1 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Phage_B PF02304.15 KLO12577.1 - 0.073 13.5 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 Scaffold protein B SDP_N PF12278.8 KLO12577.1 - 0.088 12.9 0.7 0.2 11.8 0.1 1.8 2 0 0 2 2 2 0 Sex determination protein N terminal PIF1 PF05970.14 KLO12579.1 - 0.017 14.3 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase SH3_13 PF18335.1 KLO12579.1 - 0.11 12.4 0.3 0.17 11.8 0.1 1.4 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain Herpes_Helicase PF02689.14 KLO12580.1 - 0.0026 15.8 0.0 0.0026 15.8 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KLO12580.1 - 0.043 13.7 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF4176 PF13780.6 KLO12582.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) GrpE PF01025.19 KLO12584.1 - 2.6e-41 141.1 0.8 1.8e-40 138.3 0.8 1.9 1 1 0 1 1 1 1 GrpE PAP1 PF08601.10 KLO12584.1 - 0.069 12.9 3.8 0.096 12.4 3.8 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 TMEM171 PF15471.6 KLO12585.1 - 0.016 14.2 2.1 0.031 13.3 2.1 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 DNA_repr_REX1B PF14966.6 KLO12585.1 - 0.25 12.0 6.0 0.47 11.2 2.3 2.9 1 1 2 3 3 3 0 DNA repair REX1-B AAA_23 PF13476.6 KLO12585.1 - 0.49 10.9 9.9 0.056 13.9 4.7 2.1 2 0 0 2 2 2 0 AAA domain GNT-I PF03071.15 KLO12585.1 - 0.56 8.9 3.6 1.6 7.4 0.5 2.3 2 0 0 2 2 2 0 GNT-I family DUF4407 PF14362.6 KLO12585.1 - 0.66 9.3 15.5 0.013 14.8 6.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Spore_GerAC PF05504.11 KLO12585.1 - 0.94 9.7 6.2 0.41 10.9 3.1 2.0 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal THP2 PF09432.10 KLO12585.1 - 1.5 8.9 9.2 0.25 11.4 1.5 3.0 2 1 1 3 3 3 0 Tho complex subunit THP2 Atg14 PF10186.9 KLO12585.1 - 1.6 7.7 20.1 0.15 11.1 12.9 2.6 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sds3 PF08598.11 KLO12585.1 - 2.1 8.3 10.9 0.31 11.0 4.6 2.4 2 0 0 2 2 2 0 Sds3-like TFA2_Winged_2 PF18121.1 KLO12585.1 - 3.8 7.3 6.0 0.86 9.3 0.2 2.9 3 1 0 3 3 3 0 TFA2 Winged helix domain 2 FUSC PF04632.12 KLO12585.1 - 6.8 5.1 7.5 0.61 8.5 0.5 2.2 2 1 1 3 3 3 0 Fusaric acid resistance protein family DUF3552 PF12072.8 KLO12586.1 - 0.00041 19.8 1.9 0.0036 16.8 1.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) Claudin_2 PF13903.6 KLO12586.1 - 0.04 13.7 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3915 PF13054.6 KLO12586.1 - 1.4 8.9 4.0 19 5.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) SMC_N PF02463.19 KLO12587.1 - 1.2e-27 96.8 0.0 2e-27 96.1 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KLO12587.1 - 1.4e-11 45.3 28.5 1.4e-11 45.3 28.5 5.3 3 2 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KLO12587.1 - 5.5e-07 29.6 10.9 5.5e-07 29.6 10.9 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 KLO12587.1 - 0.00012 22.1 8.4 0.00029 20.8 0.6 3.5 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KLO12587.1 - 0.00033 20.3 0.2 0.00095 18.9 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_hinge PF06470.13 KLO12587.1 - 0.0013 19.1 0.0 0.0062 16.8 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain WHH PF14414.6 KLO12587.1 - 0.13 12.1 0.1 0.4 10.6 0.1 1.8 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH PAS_10 PF13596.6 KLO12587.1 - 0.35 11.5 4.2 1.4 9.6 0.3 3.7 3 0 0 3 3 3 0 PAS domain IF-2B PF01008.17 KLO12587.1 - 3.9 6.6 6.6 0.27 10.4 0.2 2.3 2 1 1 3 3 3 0 Initiation factor 2 subunit family DUF2418 PF10332.9 KLO12588.1 - 6.2e-30 103.6 1.5 7.3e-30 103.4 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) FAD_binding_3 PF01494.19 KLO12589.1 - 1.9e-25 89.8 1.3 1.7e-24 86.7 1.3 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO12589.1 - 1.3e-07 31.2 0.3 1.5e-06 27.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO12589.1 - 1.8e-05 24.9 3.4 6.3e-05 23.1 2.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KLO12589.1 - 0.0002 20.8 0.1 0.086 12.1 0.0 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KLO12589.1 - 0.0011 17.9 0.6 0.0019 17.1 0.6 1.3 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 KLO12589.1 - 0.0025 16.6 3.0 0.0025 16.6 3.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KLO12589.1 - 0.0029 18.1 1.5 0.0068 16.9 1.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KLO12589.1 - 0.019 14.1 1.5 0.027 13.6 1.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KLO12589.1 - 0.027 13.7 0.6 0.044 13.0 0.6 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KLO12589.1 - 0.055 13.0 3.9 0.099 12.2 3.9 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.10 KLO12589.1 - 0.058 12.4 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Syndecan PF01034.20 KLO12589.1 - 0.094 12.6 0.3 0.2 11.6 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain Pyr_redox_3 PF13738.6 KLO12589.1 - 0.14 11.4 1.7 0.18 11.0 0.6 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KLO12589.1 - 0.21 10.7 2.8 0.32 10.0 2.8 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KLO12589.1 - 0.22 10.8 3.0 0.66 9.2 3.1 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KLO12589.1 - 0.5 10.2 2.3 1.1 9.1 2.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KLO12589.1 - 0.8 9.7 3.1 6.3 6.8 0.5 2.9 2 1 1 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KLO12590.1 - 6.2e-21 75.0 3.4 3.1e-19 69.4 3.4 2.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO12590.1 - 6.3e-06 25.6 0.5 6.3e-06 25.6 0.5 1.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO12590.1 - 9.3e-06 25.8 3.2 2.2e-05 24.6 3.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KLO12590.1 - 7.7e-05 22.2 0.0 0.16 11.2 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 KLO12590.1 - 0.00014 21.6 2.7 0.0004 20.1 2.7 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KLO12590.1 - 0.00049 18.9 2.2 0.00091 18.0 2.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KLO12590.1 - 0.0013 19.2 4.3 0.014 15.9 2.4 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KLO12590.1 - 0.0055 15.6 0.4 0.0055 15.6 0.4 1.4 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 KLO12590.1 - 0.007 15.5 3.4 0.011 14.9 3.4 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KLO12590.1 - 0.014 14.5 2.5 0.02 14.0 2.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KLO12590.1 - 0.059 12.6 0.6 0.12 11.6 0.6 1.4 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 KLO12590.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.18 KLO12590.1 - 0.28 11.1 1.8 0.53 10.1 1.8 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KLO12590.1 - 0.64 10.0 2.4 17 5.4 0.8 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KLO12590.1 - 1.8 7.8 3.6 2.5 7.4 3.6 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase FBPase PF00316.20 KLO12591.1 - 1.4e-75 253.0 0.6 1.7e-75 252.6 0.6 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KLO12591.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family zf-C2H2 PF00096.26 KLO12592.1 - 4.9e-22 77.1 17.6 7.8e-06 26.1 0.5 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KLO12592.1 - 1.7e-19 69.2 17.7 1.5e-06 28.3 0.1 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KLO12592.1 - 8.4e-13 48.0 16.0 0.0019 18.9 0.4 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KLO12592.1 - 2.5e-06 27.6 1.5 0.36 11.2 0.1 4.2 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KLO12592.1 - 2.6e-05 24.8 5.0 0.089 13.4 0.0 3.4 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KLO12592.1 - 2.6e-05 24.5 1.3 2.1 8.4 0.0 3.0 2 1 0 3 3 3 3 Aberrant zinc-finger zf-met PF12874.7 KLO12592.1 - 0.00023 21.4 4.3 1.5 9.3 0.0 4.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-CGNR PF11706.8 KLO12592.1 - 0.00024 20.9 2.7 4.6 7.2 0.2 3.4 3 0 0 3 3 3 2 CGNR zinc finger zf-TRAF PF02176.18 KLO12592.1 - 0.0017 19.0 5.4 0.014 16.1 2.3 2.5 1 1 2 3 3 3 1 TRAF-type zinc finger zf-H2C2_5 PF13909.6 KLO12592.1 - 0.0055 16.4 16.4 0.29 10.9 0.1 4.2 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 KLO12592.1 - 0.0079 16.5 3.2 0.65 10.3 0.8 2.7 1 1 0 2 2 2 1 C2H2-type zinc ribbon Ogr_Delta PF04606.12 KLO12592.1 - 0.0088 16.0 3.0 16 5.6 0.0 3.3 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2_11 PF16622.5 KLO12592.1 - 0.012 15.3 9.2 0.37 10.6 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Viral_helicase1 PF01443.18 KLO12592.1 - 0.029 14.1 2.2 3.8 7.2 0.4 2.4 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KLO12592.1 - 0.18 12.1 0.3 1.4 9.2 0.3 2.0 1 1 0 1 1 1 0 AAA domain CHORD PF04968.12 KLO12592.1 - 0.26 12.0 6.2 21 5.9 0.9 3.2 2 1 1 3 3 3 0 CHORD zf-DNA_Pol PF08996.10 KLO12592.1 - 0.27 11.0 2.0 0.35 10.6 0.6 1.7 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_6 PF13912.6 KLO12592.1 - 0.71 10.0 0.1 0.71 10.0 0.1 4.1 4 1 0 4 4 4 0 C2H2-type zinc finger Pmp3 PF01679.17 KLO12593.1 - 1.3e-14 54.1 5.9 1.8e-14 53.7 5.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PNGaseA PF12222.8 KLO12594.1 - 1.2e-136 456.0 4.0 1.8e-136 455.5 4.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A FTHFS PF01268.19 KLO12595.1 - 3.3e-260 864.1 0.0 4.9e-260 863.5 0.0 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KLO12595.1 - 3.9e-66 221.3 0.1 3.9e-66 221.3 0.1 2.1 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KLO12595.1 - 3.8e-36 123.9 0.3 9.2e-36 122.6 0.3 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KLO12595.1 - 0.093 11.6 1.4 0.13 11.2 0.1 1.8 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family IF2_N PF04760.15 KLO12595.1 - 0.13 12.1 0.0 16 5.4 0.0 2.7 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Coa1 PF08695.10 KLO12596.1 - 3.8e-35 120.2 0.0 4.4e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TPR_21 PF09976.9 KLO12596.1 - 0.053 13.2 0.1 0.093 12.4 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Aldo_ket_red PF00248.21 KLO12597.1 - 2.1e-57 194.6 0.0 2.4e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CDP-OH_P_transf PF01066.21 KLO12598.1 - 6.9e-13 49.2 0.2 6.9e-13 49.2 0.2 2.7 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Pex24p PF06398.11 KLO12598.1 - 5.9 5.8 6.8 8.7 5.2 0.1 2.3 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin AAA PF00004.29 KLO12599.1 - 3.1e-35 121.5 0.0 7e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KLO12599.1 - 3.6e-10 39.5 0.0 7.6e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KLO12599.1 - 3.6e-05 24.2 0.0 0.0042 17.5 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 KLO12599.1 - 0.00033 20.7 0.2 0.0023 17.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KLO12599.1 - 0.0014 18.9 0.1 0.029 14.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_6 PF12774.7 KLO12599.1 - 0.012 14.6 0.0 0.029 13.3 0.0 1.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 KLO12599.1 - 0.014 15.6 0.0 0.038 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KLO12599.1 - 0.017 15.7 0.0 0.047 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KLO12599.1 - 0.029 14.1 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KLO12599.1 - 0.032 14.0 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 KLO12599.1 - 0.052 13.8 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KLO12599.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KLO12599.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 KLO12599.1 - 0.081 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KLO12599.1 - 0.089 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 KLO12599.1 - 0.092 12.2 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 KLO12599.1 - 0.11 12.9 0.1 0.29 11.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain SMC_Nse1 PF07574.13 KLO12600.1 - 7.6e-32 110.8 0.0 3.5e-30 105.3 0.0 2.2 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KLO12600.1 - 2.8e-08 33.9 11.4 4.9e-08 33.2 11.4 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 KLO12600.1 - 0.00018 21.8 10.3 0.00029 21.1 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.6 KLO12600.1 - 0.061 13.6 9.9 0.15 12.3 10.0 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KLO12600.1 - 0.27 11.4 8.4 0.57 10.4 8.4 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain Paf1 PF03985.13 KLO12600.1 - 0.33 9.9 5.0 0.43 9.5 5.0 1.1 1 0 0 1 1 1 0 Paf1 zf-RING_5 PF14634.6 KLO12600.1 - 0.56 10.2 11.1 0.92 9.5 11.1 1.3 1 0 0 1 1 1 0 zinc-RING finger domain C1_2 PF03107.16 KLO12600.1 - 8.3 6.8 9.7 1.6 9.1 5.3 2.1 3 0 0 3 3 3 0 C1 domain CDP-OH_P_transf PF01066.21 KLO12601.1 - 2.7e-11 44.0 0.4 9.2e-11 42.4 0.4 1.8 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase CRCB PF02537.15 KLO12601.1 - 0.063 13.6 0.1 0.063 13.6 0.1 2.4 2 1 1 3 3 3 0 CrcB-like protein, Camphor Resistance (CrcB) DNA_primase_lrg PF04104.14 KLO12602.1 - 1.4e-84 283.6 0.0 1.9e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Asn_synthase PF00733.21 KLO12603.1 - 8.1e-96 321.8 0.0 2.9e-57 195.0 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KLO12603.1 - 9.5e-35 119.2 0.0 1.6e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KLO12603.1 - 5.7e-28 97.8 0.0 1.1e-27 96.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KLO12603.1 - 0.0016 17.9 0.0 0.0052 16.3 0.0 1.8 2 0 0 2 2 2 1 Aluminium induced protein QueC PF06508.13 KLO12603.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 KLO12603.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD synthase RhoGEF PF00621.20 KLO12605.1 - 5.7e-18 65.8 0.1 1.1e-13 51.8 0.1 2.3 2 0 0 2 2 2 2 RhoGEF domain Methyltransf_16 PF10294.9 KLO12606.1 - 8.7e-16 58.1 0.0 1.3e-09 38.0 0.0 2.7 2 1 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KLO12606.1 - 0.00077 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO12606.1 - 0.025 15.2 0.0 0.13 12.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KLO12606.1 - 0.08 13.7 0.0 1.3 9.8 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KLO12606.1 - 0.17 12.6 0.0 27 5.6 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain SAM_MT PF04445.13 KLO12606.1 - 0.19 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase EF_assoc_2 PF08356.12 KLO12607.1 - 0.017 15.1 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 EF hand associated EF_assoc_1 PF08355.12 KLO12607.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 EF hand associated W2 PF02020.18 KLO12608.1 - 1.5e-10 41.0 0.1 1.5e-10 41.0 0.1 2.6 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KLO12608.1 - 1.2e-06 28.0 4.8 0.011 15.4 0.5 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KLO12608.1 - 0.00064 20.1 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KLO12608.1 - 0.0092 15.0 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 KLO12608.1 - 0.15 10.2 0.1 0.32 9.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CDC45 PF02724.14 KLO12608.1 - 1.8 6.8 9.9 3.1 6.0 9.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 KLO12608.1 - 2.2 7.8 4.3 3.5 7.1 4.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hexapep_2 PF14602.6 KLO12608.1 - 2.2 8.1 9.8 2.3 8.1 1.4 3.3 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Pmp3 PF01679.17 KLO12609.1 - 3.6e-14 52.7 3.7 6.5e-14 51.9 3.7 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1751 PF08551.10 KLO12609.1 - 0.035 14.7 0.1 0.05 14.2 0.1 1.3 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Aminotran_5 PF00266.19 KLO12610.1 - 1e-09 37.8 0.0 1.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V FAD_binding_3 PF01494.19 KLO12611.1 - 1.2e-16 61.0 0.0 6.8e-16 58.4 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KLO12611.1 - 0.0001 22.0 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO12611.1 - 0.00014 22.0 0.0 0.00038 20.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO12611.1 - 0.00016 21.0 0.0 0.00041 19.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KLO12611.1 - 0.00029 20.0 0.1 0.00055 19.1 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KLO12611.1 - 0.0012 18.3 0.3 0.0053 16.1 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 KLO12611.1 - 0.0018 17.9 0.1 0.0032 17.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KLO12611.1 - 0.0025 16.6 0.0 0.0038 16.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 KLO12611.1 - 0.005 15.9 0.1 0.12 11.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 KLO12611.1 - 0.0083 16.7 0.0 0.047 14.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KLO12611.1 - 0.019 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 KLO12611.1 - 0.032 14.7 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 KLO12611.1 - 0.034 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 KLO12611.1 - 0.04 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KLO12611.1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KLO12611.1 - 0.14 11.4 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AT_hook PF02178.19 KLO12612.1 - 7.5e-05 22.2 56.6 0.0087 15.8 2.7 4.9 5 0 0 5 5 5 4 AT hook motif PRKCSH PF07915.13 KLO12613.1 - 4.1e-13 50.1 0.4 4.1e-13 50.1 0.4 1.7 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KLO12613.1 - 0.00011 21.9 0.0 0.00049 19.8 0.0 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Pkinase PF00069.25 KLO12614.1 - 4.7e-45 154.0 0.0 3.3e-44 151.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12614.1 - 2.2e-25 89.4 0.0 3.3e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO12614.1 - 0.0037 17.2 0.4 0.013 15.4 0.1 2.0 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO12614.1 - 0.01 15.1 0.0 0.028 13.7 0.0 1.6 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 KLO12614.1 - 0.013 15.1 0.0 5.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KLO12614.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pr_beta_C PF12465.8 KLO12616.1 - 0.19 11.1 0.8 0.35 10.3 0.8 1.4 1 0 0 1 1 1 0 Proteasome beta subunits C terminal 2OG-FeII_Oxy_3 PF13640.6 KLO12617.1 - 1.1e-08 35.9 0.0 1.9e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RTA1 PF04479.13 KLO12618.1 - 2.2e-54 184.2 3.9 3.4e-54 183.6 3.9 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF973 PF06157.11 KLO12618.1 - 0.31 10.0 2.0 0.64 9.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF973) ThrE PF06738.12 KLO12618.1 - 9.1 5.6 9.5 6.1 6.1 0.1 2.5 3 0 0 3 3 3 0 Putative threonine/serine exporter RTA1 PF04479.13 KLO12619.1 - 2.5e-54 184.0 5.9 3.3e-54 183.6 5.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2339 PF10101.9 KLO12619.1 - 0.0014 17.4 4.6 0.0019 16.9 4.6 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) 7TM_GPCR_Str PF10326.9 KLO12619.1 - 0.04 13.3 9.3 0.22 10.9 9.3 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str Kelch_4 PF13418.6 KLO12620.1 - 1.3e-18 66.7 4.6 4e-11 42.8 0.0 5.9 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KLO12620.1 - 1.6e-13 50.5 11.5 0.0065 16.7 0.1 7.1 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KLO12620.1 - 8.7e-13 47.6 0.7 2.7e-06 26.8 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 KLO12620.1 - 3.9e-12 46.0 1.9 0.00032 20.9 0.1 5.0 4 2 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 KLO12620.1 - 9.1e-09 35.1 4.0 0.007 16.3 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KLO12620.1 - 1.1e-05 25.1 4.1 0.028 14.4 0.1 4.6 5 0 0 5 5 5 2 Kelch motif DEAD PF00270.29 KLO12621.1 - 2.2e-46 157.8 0.0 3.5e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO12621.1 - 1.6e-31 108.9 0.0 5.2e-31 107.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO12621.1 - 3e-05 24.1 0.0 5.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RNA_pol_Rpb1_1 PF04997.12 KLO12622.1 - 2.1e-110 368.9 0.0 3.2e-110 368.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KLO12622.1 - 1.1e-100 336.5 0.0 1.6e-100 335.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KLO12622.1 - 6.3e-74 247.7 0.0 1.3e-73 246.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KLO12622.1 - 7e-64 215.2 0.1 1.4e-63 214.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KLO12622.1 - 2.9e-51 173.5 0.0 2.9e-50 170.2 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KLO12622.1 - 2.1e-49 167.0 0.2 4.3e-49 166.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 KLO12622.1 - 8.5e-35 119.0 0.0 2e-34 117.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KLO12622.1 - 1.7e-06 28.1 195.2 0.027 14.8 2.7 13.9 11 2 1 12 12 12 8 RNA polymerase Rpb1 C-terminal repeat TRAPPC10 PF12584.8 KLO12624.1 - 2.6e-26 92.2 0.0 5.6e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 ALG3 PF05208.13 KLO12625.1 - 4.3e-133 444.2 11.8 6.4e-133 443.6 11.8 1.2 1 0 0 1 1 1 1 ALG3 protein Cellulase PF00150.18 KLO12626.1 - 4e-16 59.3 0.2 9.8e-16 58.0 0.2 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CH_2 PF06294.11 KLO12626.1 - 0.092 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 CH-like domain in sperm protein PIG-H PF10181.9 KLO12627.1 - 9.7e-15 54.2 0.0 1.4e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Ist1 PF03398.14 KLO12628.1 - 3.1e-41 141.0 0.4 5e-41 140.4 0.4 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.18 KLO12628.1 - 7.2e-17 61.8 0.1 6e-14 52.2 0.0 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain GPI-anchored PF10342.9 KLO12629.1 - 8.4e-09 36.1 3.1 8.4e-09 36.1 3.1 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tissue_fac PF01108.17 KLO12629.1 - 0.023 14.5 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 Tissue factor RAP1 PF07218.11 KLO12629.1 - 3.8 5.7 7.4 4.3 5.5 7.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Period_C PF12114.8 KLO12629.1 - 7 6.2 9.2 9.8 5.7 9.2 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Asp PF00026.23 KLO12630.1 - 1.1e-46 159.7 2.9 3.2e-46 158.2 2.9 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO12630.1 - 4.2e-08 33.6 1.0 0.00083 19.6 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KLO12630.1 - 0.095 12.5 0.7 6.1 6.6 0.1 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal HEAT_2 PF13646.6 KLO12633.1 - 7.7e-14 51.8 10.4 1.5e-05 25.3 0.0 5.8 5 1 0 5 5 5 3 HEAT repeats HEAT PF02985.22 KLO12633.1 - 9.7e-14 50.3 23.5 0.00048 20.2 0.2 9.4 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.6 KLO12633.1 - 4.1e-07 30.4 4.5 3.6 8.2 0.0 6.6 6 0 0 6 6 6 3 HEAT-like repeat Cnd1 PF12717.7 KLO12633.1 - 0.00064 19.8 0.0 0.18 11.8 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KLO12633.1 - 0.081 11.5 0.2 2.5 6.5 0.0 2.6 2 1 0 3 3 3 0 Adaptin N terminal region HEAT_PBS PF03130.16 KLO12633.1 - 0.17 12.7 1.5 13 6.8 0.0 4.2 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Ipi1_N PF12333.8 KLO12633.1 - 0.18 12.4 4.3 0.78 10.4 0.0 3.2 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DUF4632 PF15451.6 KLO12634.1 - 0.026 14.6 0.2 0.052 13.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Aminotran_1_2 PF00155.21 KLO12635.1 - 5.8e-83 279.0 0.0 6.6e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-AN1 PF01428.16 KLO12636.1 - 1.9e-10 40.7 6.3 2.6e-10 40.3 6.3 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.21 KLO12636.1 - 0.02 15.1 2.2 0.028 14.6 2.2 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain C5HCH PF17982.1 KLO12636.1 - 0.15 12.2 6.3 0.11 12.7 4.7 1.6 1 1 0 1 1 1 0 NSD Cys-His rich domain GPI-anchored PF10342.9 KLO12637.1 - 8.1e-06 26.5 0.1 1e-05 26.2 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ion_trans PF00520.31 KLO12638.1 - 0.0001 21.6 0.2 0.00013 21.3 0.2 1.1 1 0 0 1 1 1 1 Ion transport protein KIP1 PF07765.12 KLO12638.1 - 0.038 14.1 0.2 0.084 13.0 0.2 1.5 1 0 0 1 1 1 0 KIP1-like protein Syntaxin PF00804.25 KLO12639.1 - 3.2e-18 66.2 10.9 3.2e-18 66.2 10.9 2.2 2 1 0 2 2 1 1 Syntaxin SNARE PF05739.19 KLO12639.1 - 2.7e-09 36.9 6.6 1.1e-08 34.9 6.5 2.1 1 1 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KLO12639.1 - 0.0027 18.0 14.5 0.0042 17.4 2.5 3.1 1 1 2 3 3 3 1 Syntaxin-like protein PBP1_TM PF14812.6 KLO12639.1 - 0.004 17.5 0.1 0.004 17.5 0.1 2.4 2 1 0 2 2 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal SKA1 PF07160.12 KLO12639.1 - 0.0047 16.8 1.3 0.0047 16.8 1.3 2.1 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 1 MCU PF04678.13 KLO12639.1 - 0.0068 16.5 0.4 0.0068 16.5 0.4 2.0 2 0 0 2 2 2 1 Mitochondrial calcium uniporter DUF3611 PF12263.8 KLO12639.1 - 0.026 14.4 0.5 0.06 13.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) LMBR1 PF04791.16 KLO12639.1 - 0.026 13.4 3.0 0.037 12.9 3.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Mobilization_B PF17511.2 KLO12639.1 - 0.031 14.6 5.1 0.069 13.5 4.2 2.0 1 1 1 2 2 2 0 Mobilization protein B Use1 PF09753.9 KLO12639.1 - 0.033 13.9 8.6 0.067 12.9 8.6 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 MCPsignal PF00015.21 KLO12639.1 - 0.036 13.9 3.1 0.09 12.6 0.4 2.4 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4727 PF15856.5 KLO12639.1 - 0.042 13.4 0.4 0.058 13.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) Orf78 PF06024.12 KLO12639.1 - 0.051 13.9 0.2 0.17 12.2 0.2 1.9 1 0 0 1 1 1 0 Orf78 (ac78) EMP24_GP25L PF01105.24 KLO12639.1 - 0.096 12.6 7.8 0.49 10.3 7.7 2.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Tweety PF04906.13 KLO12639.1 - 0.15 10.7 2.4 0.11 11.2 0.6 1.6 2 0 0 2 2 2 0 Tweety Tropomyosin PF00261.20 KLO12639.1 - 0.17 11.2 15.4 0.7 9.2 3.1 2.2 2 0 0 2 2 2 0 Tropomyosin Sarcoglycan_1 PF04790.13 KLO12639.1 - 0.29 10.4 6.9 0.78 9.0 6.9 1.6 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein DotU PF09850.9 KLO12639.1 - 0.4 10.4 6.9 0.18 11.5 1.1 2.8 2 2 0 2 2 2 0 Type VI secretion system protein DotU Baculo_PEP_C PF04513.12 KLO12639.1 - 0.5 10.4 4.6 1.9 8.5 1.6 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 KLO12639.1 - 0.58 10.2 9.2 0.43 10.6 3.3 2.6 2 1 1 3 3 3 0 Laminin Domain II Wzz PF02706.15 KLO12639.1 - 0.73 10.2 3.8 2.2 8.6 3.8 1.8 1 0 0 1 1 1 0 Chain length determinant protein Sigma_reg_N PF13800.6 KLO12639.1 - 0.89 9.9 5.0 16 5.9 3.8 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF1759 PF03564.15 KLO12639.1 - 0.91 9.5 4.7 0.9 9.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF1664 PF07889.12 KLO12639.1 - 1.3 9.0 10.3 4.9 7.2 1.5 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KLO12639.1 - 1.7 8.8 11.2 3.5 7.8 1.3 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.13 KLO12639.1 - 2.9 7.4 6.1 1.1 8.8 1.8 2.4 2 1 0 2 2 2 0 fzo-like conserved region RmuC PF02646.16 KLO12639.1 - 3.4 6.7 10.6 0.25 10.4 1.7 2.8 3 0 0 3 3 3 0 RmuC family FlaC_arch PF05377.11 KLO12639.1 - 3.5 8.1 8.5 26 5.3 0.6 4.5 2 2 2 5 5 5 0 Flagella accessory protein C (FlaC) DUF4337 PF14235.6 KLO12639.1 - 3.9 7.6 11.2 0.54 10.4 2.2 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4337) DUF4404 PF14357.6 KLO12639.1 - 5 7.8 9.9 9.8 6.9 0.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DUF5344 PF17279.2 KLO12639.1 - 5 7.8 7.8 30 5.3 0.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5344) DUF4192 PF13830.6 KLO12639.1 - 5 7.1 8.0 1.3 9.0 2.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4192) Prominin PF05478.11 KLO12639.1 - 7.2 4.4 13.8 2.1 6.2 2.1 2.3 1 1 2 3 3 3 0 Prominin PCRF PF03462.18 KLO12639.1 - 9.6 6.0 11.4 1.3 8.9 3.5 2.3 1 1 1 2 2 2 0 PCRF domain Lyase_1 PF00206.20 KLO12640.1 - 1.6e-101 339.8 0.0 3e-101 338.9 0.0 1.4 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 KLO12640.1 - 6.1e-26 91.0 0.2 1.5e-25 89.7 0.2 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF3176 PF11374.8 KLO12642.1 - 1.4e-05 25.2 9.5 0.02 15.1 0.8 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3176) zf-UBR PF02207.20 KLO12642.1 - 0.071 13.3 0.9 0.22 11.7 0.1 2.1 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) T7SS_ESX1_EccB PF05108.13 KLO12642.1 - 0.12 11.0 0.3 0.21 10.2 0.3 1.2 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B DUF3433 PF11915.8 KLO12642.1 - 0.21 12.1 7.7 0.36 11.3 0.5 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3433) SpoOE-like PF09388.10 KLO12642.1 - 0.25 11.3 0.5 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein DUF3176 PF11374.8 KLO12643.1 - 0.091 13.0 4.7 0.18 12.0 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) PDR_CDR PF06422.12 KLO12643.1 - 0.13 12.1 0.3 0.72 9.8 0.0 2.4 3 0 0 3 3 3 0 CDR ABC transporter F-box PF00646.33 KLO12644.1 - 4.9e-05 23.1 0.2 0.00012 21.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO12644.1 - 0.023 14.6 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 KLO12644.1 - 0.069 13.0 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 F-box NAD_binding_4 PF07993.12 KLO12645.1 - 2.2e-31 109.0 0.0 3.3e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KLO12645.1 - 5.7e-24 84.5 0.0 1.1e-23 83.5 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KLO12645.1 - 1.2e-07 31.4 0.0 1.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KLO12645.1 - 3.2e-06 27.4 0.2 1.3e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Lipase_3 PF01764.25 KLO12646.1 - 5.3e-23 81.5 0.0 7.5e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KLO12646.1 - 0.023 15.3 0.1 0.026 15.1 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Aldo_ket_red PF00248.21 KLO12648.1 - 4.5e-69 232.9 0.0 5.8e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Takusan PF04822.13 KLO12648.1 - 0.21 11.5 0.2 0.49 10.3 0.0 1.8 2 0 0 2 2 2 0 Takusan Adaptin_N PF01602.20 KLO12649.1 - 0.12 10.9 0.1 1.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Adaptin N terminal region SET PF00856.28 KLO12650.1 - 8.4e-11 42.5 0.0 7.3e-10 39.5 0.0 2.5 1 1 0 1 1 1 1 SET domain DUF3127 PF11325.8 KLO12650.1 - 0.077 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) DUF3176 PF11374.8 KLO12651.1 - 0.0019 18.4 10.4 0.017 15.3 1.5 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3176) Autoind_synth PF00765.17 KLO12651.1 - 0.17 11.4 0.1 0.37 10.3 0.1 1.5 1 0 0 1 1 1 0 Autoinducer synthase DUF3176 PF11374.8 KLO12652.1 - 0.2 11.8 6.4 6.4 7.0 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) DUF3176 PF11374.8 KLO12654.1 - 0.081 13.1 6.2 0.47 10.7 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Lar_N PF09861.9 KLO12655.1 - 0.12 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Lactate racemase N-terminal domain DUF3176 PF11374.8 KLO12656.1 - 0.026 14.7 4.2 0.083 13.1 4.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) DUF3176 PF11374.8 KLO12657.1 - 8.3e-06 26.0 7.5 0.032 14.4 2.0 3.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3176) DUF3176 PF11374.8 KLO12658.1 - 0.11 12.7 8.6 0.62 10.3 1.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) E7R PF17467.2 KLO12660.1 - 0.13 12.4 0.0 0.73 10.0 0.0 2.2 2 0 0 2 2 2 0 Viral Protein E7 UPF0016 PF01169.19 KLO12660.1 - 1.1 9.6 11.4 0.13 12.6 0.5 3.5 4 0 0 4 4 4 0 Uncharacterized protein family UPF0016 TPR_16 PF13432.6 KLO12661.1 - 6.5e-10 39.5 5.4 1.4e-05 25.6 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO12661.1 - 5.1e-07 29.3 7.0 0.3 11.3 0.7 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KLO12661.1 - 2.3e-06 27.2 3.1 0.049 13.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KLO12661.1 - 6e-06 26.5 1.7 1.7 9.0 3.1 4.2 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KLO12661.1 - 0.00016 22.1 1.4 0.016 15.8 0.4 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat SET PF00856.28 KLO12661.1 - 0.00065 20.1 0.0 0.0074 16.7 0.0 2.4 1 1 0 1 1 1 1 SET domain TPR_14 PF13428.6 KLO12661.1 - 0.0013 19.4 1.7 0.015 16.1 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO12661.1 - 0.024 14.8 3.3 0.42 10.9 0.5 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KLO12661.1 - 0.034 14.3 0.5 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KLO12661.1 - 0.036 14.6 4.2 0.31 11.6 0.1 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat SAF PF08666.12 KLO12661.1 - 0.036 14.7 0.0 0.59 10.8 0.0 2.5 2 0 0 2 2 2 0 SAF domain TPR_7 PF13176.6 KLO12661.1 - 0.063 13.3 1.3 13 6.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat EB_dh PF09459.10 KLO12663.1 - 0.025 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase Transketolase_N PF00456.21 KLO12664.1 - 8.4e-15 54.5 0.5 8.9e-14 51.2 0.5 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KLO12664.1 - 3.6e-10 39.8 0.0 8.1e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KLO12664.1 - 1.2e-05 25.1 0.4 2.2e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KLO12664.1 - 0.00072 18.6 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KLO12664.1 - 0.0012 18.7 0.1 0.0052 16.6 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain UBX PF00789.20 KLO12666.1 - 5e-07 29.8 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 KLO12666.1 - 1e-05 25.6 0.0 2.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Radial_spoke_3 PF06098.11 KLO12666.1 - 0.55 9.4 10.2 0.92 8.7 10.2 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 HRG PF16954.5 KLO12667.1 - 4.9 7.6 10.4 0.23 11.9 0.6 3.3 3 1 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene HRG PF16954.5 KLO12669.1 - 1.2 9.6 4.6 1.5 9.3 0.8 2.8 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene PARP PF00644.20 KLO12670.1 - 1.2e-09 38.0 3.8 6.8e-09 35.6 1.1 2.8 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Ehrlichia_rpt PF09528.10 KLO12673.1 - 0.049 13.1 0.2 0.1 12.1 0.2 1.5 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) DUF3220 PF11516.8 KLO12673.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) PI_PP_I PF18363.1 KLO12674.1 - 0.0085 16.2 0.3 0.014 15.5 0.3 1.4 1 1 0 1 1 1 1 Phosphoinositide phosphatase insertion domain OmpH PF03938.14 KLO12674.1 - 0.022 15.1 2.0 0.028 14.8 2.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.11 KLO12674.1 - 0.027 15.0 2.4 0.036 14.6 2.4 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF3120 PF11318.8 KLO12674.1 - 0.027 14.8 0.0 0.033 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) GAS PF13851.6 KLO12674.1 - 0.034 13.5 4.1 0.042 13.2 4.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Z1 PF10593.9 KLO12674.1 - 0.043 13.3 0.6 0.048 13.2 0.6 1.1 1 0 0 1 1 1 0 Z1 domain Spectrin PF00435.21 KLO12674.1 - 0.052 14.0 4.9 0.074 13.5 4.9 1.1 1 0 0 1 1 1 0 Spectrin repeat Mis14 PF08641.12 KLO12674.1 - 0.069 13.5 4.3 0.12 12.7 4.3 1.4 1 1 0 1 1 1 0 Kinetochore protein Mis14 like Spc7 PF08317.11 KLO12674.1 - 0.08 11.8 4.6 0.11 11.4 4.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein UxaE PF16257.5 KLO12674.1 - 0.089 11.4 0.2 0.1 11.3 0.2 1.0 1 0 0 1 1 1 0 tagaturonate epimerase NAD_binding_5 PF07994.12 KLO12674.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase FapA PF03961.13 KLO12674.1 - 0.21 10.2 0.3 0.22 10.1 0.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 KLO12674.1 - 0.52 10.4 4.4 1 9.4 4.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FAA_hydro_N_2 PF18288.1 KLO12674.1 - 0.64 10.5 3.2 1.1 9.7 0.4 2.1 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 DUF3288 PF11691.8 KLO12674.1 - 2.4 8.2 5.7 1.2 9.2 0.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3288) DUF948 PF06103.11 KLO12675.1 - 0.098 12.9 1.0 2 8.7 0.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) rRNA_proc-arch PF13234.6 KLO12675.1 - 0.15 12.0 2.2 0.77 9.6 0.8 2.4 2 1 0 2 2 2 0 rRNA-processing arch domain Exonuc_VII_S PF02609.16 KLO12675.1 - 0.17 12.0 2.3 3.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Exonuclease VII small subunit DUF16 PF01519.16 KLO12677.1 - 0.00045 20.7 1.3 0.23 12.0 0.3 2.8 3 0 0 3 3 3 2 Protein of unknown function DUF16 Fzo_mitofusin PF04799.13 KLO12677.1 - 0.0073 15.9 0.2 0.65 9.5 0.2 2.5 2 0 0 2 2 2 1 fzo-like conserved region BORCS8 PF10167.9 KLO12677.1 - 0.013 15.4 0.8 1.5 8.7 0.0 3.0 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 8 Apolipoprotein PF01442.18 KLO12677.1 - 0.034 14.0 0.0 0.31 10.9 0.0 2.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain HSBP1 PF06825.12 KLO12677.1 - 0.092 12.6 1.4 0.33 10.9 0.1 2.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 BLOC1S3 PF15753.5 KLO12677.1 - 0.31 11.1 2.6 0.24 11.5 0.6 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 ADIP PF11559.8 KLO12677.1 - 0.44 10.6 4.3 3 7.9 0.9 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 KLO12677.1 - 0.49 9.9 3.2 1.6 8.3 2.9 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit DASH_Duo1 PF08651.10 KLO12677.1 - 0.62 9.9 6.5 0.92 9.3 0.0 3.6 3 1 1 4 4 4 0 DASH complex subunit Duo1 YPEB PF14620.6 KLO12677.1 - 1 8.6 5.1 2.1 7.6 0.3 2.9 2 2 1 3 3 3 0 YpeB sporulation Apolipoprotein PF01442.18 KLO12678.1 - 0.0098 15.8 1.0 5.9 6.7 0.2 2.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Spc24 PF08286.11 KLO12678.1 - 0.019 15.2 2.7 0.18 12.0 0.0 3.2 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Syntaxin PF00804.25 KLO12678.1 - 0.061 13.0 3.0 1.8 8.2 0.1 2.7 1 1 1 2 2 2 0 Syntaxin CENP-F_leu_zip PF10473.9 KLO12678.1 - 0.071 13.1 6.9 0.19 11.8 2.9 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5082 PF16888.5 KLO12678.1 - 0.12 12.7 7.1 0.79 10.0 0.2 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) DUF4140 PF13600.6 KLO12678.1 - 0.12 12.8 0.5 1.8 9.0 0.1 2.8 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF724 PF05266.14 KLO12678.1 - 0.16 11.8 4.4 0.13 12.1 0.9 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 KLO12678.1 - 0.7 9.9 6.4 11 6.1 0.6 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 KLO12678.1 - 0.87 9.9 4.8 43 4.5 4.3 3.2 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) FAM184 PF15665.5 KLO12678.1 - 3.3 7.4 10.1 0.39 10.5 1.7 2.6 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B APG6_N PF17675.1 KLO12678.1 - 4.1 7.9 9.6 0.48 11.0 1.5 2.7 2 1 0 3 3 3 0 Apg6 coiled-coil region Lipase_C PF18067.1 KLO12680.1 - 0.14 12.7 0.1 1.1 9.9 0.1 2.0 2 0 0 2 2 2 0 Lipase C-terminal domain Zn_clus PF00172.18 KLO12681.1 - 0.0022 18.1 11.9 0.0049 17.0 11.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_Tnp_Tc5 PF03221.16 KLO12683.1 - 0.086 12.9 0.1 4.1 7.5 0.0 2.4 2 1 0 2 2 2 0 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KLO12684.1 - 2.7e-17 63.0 0.0 4.1e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CDP-OH_P_transf PF01066.21 KLO12688.1 - 1.9e-14 54.2 1.0 1.9e-14 54.2 1.0 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UAA PF08449.11 KLO12689.1 - 6.5e-72 242.3 9.7 7.5e-72 242.1 9.7 1.0 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KLO12689.1 - 0.00084 18.7 10.9 0.01 15.1 10.9 2.0 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 KLO12689.1 - 0.0023 18.1 25.2 0.061 13.5 7.1 3.0 2 1 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 KLO12689.1 - 0.007 15.4 0.4 0.007 15.4 0.4 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Nup35_RRM PF05172.13 KLO12690.1 - 3.2e-05 23.8 0.0 0.00054 19.9 0.0 2.2 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CBP_BcsO PF17037.5 KLO12690.1 - 0.071 13.3 4.3 0.099 12.8 1.5 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO EDS1_EP PF18117.1 KLO12691.1 - 0.031 14.7 0.9 0.067 13.6 0.7 1.7 1 1 0 1 1 1 0 Enhanced disease susceptibility 1 protein EP domain Spc7 PF08317.11 KLO12691.1 - 0.13 11.1 33.7 0.15 10.9 8.3 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein TACC_C PF05010.14 KLO12691.1 - 0.7 9.6 30.0 1.7 8.4 24.7 3.0 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Fez1 PF06818.15 KLO12691.1 - 0.98 9.8 33.9 0.16 12.4 18.4 3.1 2 1 1 3 3 3 0 Fez1 Fib_alpha PF08702.10 KLO12691.1 - 2.4 8.3 19.1 5.5 7.2 1.9 4.1 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF4047 PF13256.6 KLO12691.1 - 3.6 7.8 13.9 0.69 10.1 0.6 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4047) NMO PF03060.15 KLO12692.1 - 1.8e-46 159.1 0.1 2.6e-46 158.6 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KLO12692.1 - 6e-06 25.5 0.0 5.3e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KLO12692.1 - 0.061 12.3 2.3 0.091 11.8 2.3 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Pkinase PF00069.25 KLO12693.1 - 1.1e-65 221.6 0.0 2.5e-65 220.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12693.1 - 1.2e-35 123.1 0.0 1.7e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO12693.1 - 7.4e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO12693.1 - 4.3e-05 22.5 0.2 7.1e-05 21.8 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO12693.1 - 0.00061 19.2 1.1 0.0018 17.6 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO12693.1 - 0.0017 18.3 0.1 0.0035 17.3 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KLO12693.1 - 0.015 14.2 0.1 0.024 13.6 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KLO12693.1 - 0.017 14.8 0.0 0.061 12.9 0.0 1.9 1 0 0 1 1 1 0 RIO1 family Guanylate_kin PF00625.21 KLO12694.1 - 1.6e-65 220.2 0.0 1.9e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KLO12694.1 - 3.5e-07 30.8 0.0 7.2e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KLO12694.1 - 3.8e-05 23.9 0.0 0.00038 20.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KLO12694.1 - 0.00046 20.5 0.0 0.0014 18.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KLO12694.1 - 0.00054 20.0 0.0 0.00089 19.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO12694.1 - 0.0013 18.7 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 KLO12694.1 - 0.0019 18.5 0.0 0.0032 17.8 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 KLO12694.1 - 0.0032 17.4 0.0 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 KLO12694.1 - 0.0047 17.5 0.0 0.014 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KLO12694.1 - 0.0072 16.8 0.1 0.13 12.7 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KLO12694.1 - 0.0075 16.3 0.0 0.019 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KLO12694.1 - 0.012 15.4 0.0 0.66 9.8 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase ABC_tran PF00005.27 KLO12694.1 - 0.023 15.2 0.0 0.029 14.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 KLO12694.1 - 0.024 13.9 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KLO12694.1 - 0.032 14.5 0.1 0.14 12.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KLO12694.1 - 0.035 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KLO12694.1 - 0.037 13.7 0.1 0.092 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KLO12694.1 - 0.038 13.5 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein ATPase_2 PF01637.18 KLO12694.1 - 0.048 13.6 0.0 0.078 12.9 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KLO12694.1 - 0.055 13.5 0.0 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) GAT PF03127.14 KLO12694.1 - 0.062 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 GAT domain Rad17 PF03215.15 KLO12694.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 KLO12694.1 - 0.077 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 KLO12694.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 KLO12694.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Septin Roc PF08477.13 KLO12694.1 - 0.19 11.9 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MFS_1 PF07690.16 KLO12696.1 - 4.5e-17 62.0 6.1 5.1e-17 61.8 6.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO12696.1 - 1.9e-05 23.7 1.4 3.5e-05 22.8 1.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter PACT_coil_coil PF10495.9 KLO12697.1 - 1.3e-14 54.5 0.4 1.3e-14 54.5 0.4 2.9 3 1 0 3 3 3 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Tektin PF03148.14 KLO12697.1 - 0.038 12.8 20.2 0.029 13.2 4.0 3.2 1 1 2 3 3 3 0 Tektin family Spc7 PF08317.11 KLO12697.1 - 0.12 11.2 24.7 6.9 5.5 21.9 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein BRE1 PF08647.11 KLO12697.1 - 0.3 11.2 22.5 0.34 11.0 5.6 2.9 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF948 PF06103.11 KLO12697.1 - 0.59 10.4 2.2 13 6.1 0.1 3.3 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 KLO12697.1 - 0.65 10.2 13.4 0.7 10.1 3.4 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tup_N PF08581.10 KLO12697.1 - 0.67 10.3 17.7 1.9 8.8 7.7 4.0 2 2 1 3 3 3 0 Tup N-terminal Spc24 PF08286.11 KLO12697.1 - 1.1 9.6 11.3 5.8 7.2 2.3 2.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 KLO12697.1 - 1.6 9.3 33.9 0.45 11.1 9.7 3.7 3 1 0 4 4 4 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KLO12697.1 - 2.6 8.1 29.5 0.46 10.6 7.4 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KLO12697.1 - 4.6 6.5 20.2 28 3.9 20.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 KLO12697.1 - 9.6 6.3 22.2 3.4 7.7 3.4 3.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Vps5 PF09325.10 KLO12698.1 - 6.1e-57 192.9 7.2 1e-56 192.2 7.2 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KLO12698.1 - 4.2e-24 84.7 0.0 1.2e-23 83.2 0.0 1.8 1 0 0 1 1 1 1 PX domain SAS4 PF15460.6 KLO12699.1 - 0.022 14.8 0.1 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 MIT PF04212.18 KLO12699.1 - 0.038 14.1 0.6 0.099 12.7 0.6 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain F-box-like PF12937.7 KLO12699.1 - 0.054 13.4 1.3 0.11 12.4 1.3 1.6 1 0 0 1 1 1 0 F-box-like ssDNA_DBD PF18333.1 KLO12699.1 - 0.066 13.3 0.2 0.16 12.1 0.2 1.6 1 0 0 1 1 1 0 Non-canonical single-stranded DNA-binding domain F-box PF00646.33 KLO12699.1 - 0.069 13.1 2.7 0.062 13.2 1.1 1.7 2 0 0 2 2 2 0 F-box domain TPR_11 PF13414.6 KLO12699.1 - 0.096 12.4 1.3 0.76 9.5 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 KLO12699.1 - 0.11 12.3 0.5 0.6 10.0 0.7 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KLO12699.1 - 0.15 12.3 1.2 0.36 11.0 1.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DnaJ PF00226.31 KLO12700.1 - 4.9e-25 87.4 0.5 1.1e-24 86.4 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 KLO12700.1 - 6.4e-25 87.4 0.6 1.5e-24 86.3 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.17 KLO12700.1 - 0.087 13.0 0.2 0.28 11.4 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Cyd_oper_YbgE PF09600.10 KLO12701.1 - 0.0024 18.2 0.3 0.003 17.9 0.3 1.2 1 0 0 1 1 1 1 Cyd operon protein YbgE (Cyd_oper_YbgE) WD40 PF00400.32 KLO12702.1 - 4.2e-13 49.5 2.2 0.37 11.8 0.2 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Ribosomal_L37ae PF01780.19 KLO12704.1 - 2e-40 136.7 9.5 2.3e-40 136.6 9.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 KLO12704.1 - 0.0019 18.1 2.5 0.0029 17.5 2.5 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-RING_13 PF17977.1 KLO12704.1 - 0.0069 16.5 2.5 0.0094 16.1 2.5 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-BED PF02892.15 KLO12704.1 - 0.024 14.6 3.8 0.7 10.0 0.3 2.2 1 1 1 2 2 2 0 BED zinc finger Elf1 PF05129.13 KLO12704.1 - 0.088 12.9 2.6 0.13 12.4 2.6 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like NST1 PF13945.6 KLO12704.1 - 0.1 12.7 0.7 0.14 12.3 0.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator C1_2 PF03107.16 KLO12704.1 - 0.47 10.8 3.0 2.7 8.4 3.2 1.8 1 1 0 1 1 1 0 C1 domain A2L_zn_ribbon PF08792.10 KLO12704.1 - 0.57 10.0 4.0 1.8 8.4 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.6 KLO12704.1 - 4.8 7.8 6.8 13 6.4 0.6 2.3 1 1 1 2 2 2 0 Zinc-finger double domain DUF1712 PF08217.11 KLO12705.1 - 3.8e-25 88.5 0.0 1.6e-22 79.8 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) UCH PF00443.29 KLO12706.1 - 2.1e-68 230.6 0.0 6e-68 229.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KLO12706.1 - 3.1e-13 50.0 0.1 1.8e-05 24.5 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KLO12706.1 - 3.9e-13 49.8 0.0 1e-12 48.5 0.0 1.8 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.6 KLO12706.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Ank_2 PF12796.7 KLO12707.1 - 1e-11 45.2 0.1 0.00063 20.3 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KLO12707.1 - 3.2e-10 40.3 0.4 1e-05 26.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KLO12707.1 - 9.4e-10 37.9 0.5 0.021 15.3 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KLO12707.1 - 1.7e-05 25.0 3.3 0.03 14.6 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KLO12707.1 - 0.00045 20.0 0.6 0.019 14.8 0.1 2.8 2 1 0 2 2 2 1 KilA-N domain Ank PF00023.30 KLO12707.1 - 0.00081 19.7 9.0 0.029 14.8 0.2 3.9 5 0 0 5 5 5 2 Ankyrin repeat DUF3450 PF11932.8 KLO12707.1 - 0.82 8.9 7.9 0.47 9.7 5.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) WD40 PF00400.32 KLO12708.1 - 2.2e-43 145.4 10.4 5.1e-08 33.4 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 KLO12708.1 - 5.8e-14 51.3 1.3 1.5e-13 50.0 1.3 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KLO12708.1 - 8.2e-14 51.7 0.0 0.73 10.2 0.0 6.5 3 2 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KLO12708.1 - 7.3e-05 22.2 0.2 1.1 8.5 0.0 3.5 3 1 1 5 5 5 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KLO12708.1 - 0.00011 21.7 0.0 0.7 9.2 0.0 3.3 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 KLO12708.1 - 0.0042 16.1 0.0 3.6 6.5 0.0 4.1 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PMT PF02366.18 KLO12709.1 - 1.5e-85 286.7 13.0 3.1e-85 285.7 13.0 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KLO12709.1 - 1.2e-64 217.6 1.9 1.2e-64 217.6 1.9 3.3 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KLO12709.1 - 9.7e-17 61.4 0.6 3e-16 59.8 0.6 1.8 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.6 KLO12709.1 - 7.1e-06 26.3 11.6 7.1e-06 26.3 11.6 3.0 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Transport_MerF PF11431.8 KLO12709.1 - 0.1 12.5 4.6 0.078 12.9 0.9 2.7 2 0 0 2 2 2 0 Membrane transport protein MerF DUF4395 PF14340.6 KLO12709.1 - 5.5 7.3 8.7 0.73 10.2 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) DUF1179 PF06678.11 KLO12710.1 - 0.13 12.3 2.2 0.5 10.4 2.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) AT_hook PF02178.19 KLO12710.1 - 0.55 10.3 7.7 1.4 9.0 7.7 1.7 1 0 0 1 1 1 0 AT hook motif DAO PF01266.24 KLO12711.1 - 7.6e-38 131.0 0.0 9e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO12711.1 - 1e-05 25.6 0.3 0.00011 22.3 0.9 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KLO12711.1 - 0.0021 17.4 0.4 0.0036 16.6 0.4 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KLO12711.1 - 0.0034 16.7 0.1 0.0064 15.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KLO12711.1 - 0.0061 15.9 0.0 1.6 8.0 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KLO12711.1 - 0.011 15.7 0.7 0.31 11.0 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding MCRA PF06100.11 KLO12711.1 - 0.057 12.2 0.2 0.078 11.8 0.2 1.1 1 0 0 1 1 1 0 MCRA family Pyr_redox_3 PF13738.6 KLO12711.1 - 0.11 11.7 0.1 5.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf_CCCH_4 PF18345.1 KLO12712.1 - 2.7e-11 43.1 25.9 0.00028 20.8 2.8 5.4 5 0 0 5 5 5 5 Zinc finger domain zf-CCCH PF00642.24 KLO12712.1 - 8.6e-11 41.5 25.3 0.0025 17.7 2.1 5.2 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KLO12712.1 - 0.0069 17.1 25.7 0.13 12.9 0.5 5.1 1 1 4 5 5 5 2 Torus domain zf-CCCH_3 PF15663.5 KLO12712.1 - 0.028 14.6 13.6 0.033 14.4 5.2 2.9 1 1 2 3 3 3 0 Zinc-finger containing family TBX PF12598.8 KLO12712.1 - 0.48 11.3 8.2 1.7 9.5 8.2 1.9 1 0 0 1 1 1 0 T-box transcription factor zf-CCCH_4 PF18044.1 KLO12712.1 - 2.9 7.8 27.3 0.34 10.8 1.3 5.1 5 0 0 5 5 5 0 CCCH-type zinc finger Dak1 PF02733.17 KLO12713.1 - 1.9e-111 371.9 0.1 2.5e-111 371.5 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KLO12713.1 - 6.3e-40 136.9 0.7 1.2e-39 136.0 0.7 1.5 1 0 0 1 1 1 1 DAK2 domain TFIIS_M PF07500.14 KLO12715.1 - 4.2e-16 59.4 0.7 9.9e-16 58.2 0.7 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 KLO12715.1 - 3.6e-12 46.5 0.0 6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 KLO12716.1 - 1e-07 31.7 1.1 2e-07 30.8 1.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KLO12716.1 - 0.0081 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 KLO12716.1 - 0.14 11.8 0.3 0.14 11.8 0.3 1.8 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Apt1 PF10351.9 KLO12716.1 - 0.21 10.4 1.4 0.25 10.2 1.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF5528 PF17666.1 KLO12716.1 - 1.8 8.5 7.3 3.6 7.5 7.3 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5528) Macoilin PF09726.9 KLO12716.1 - 2.1 6.8 4.8 2.1 6.8 4.8 1.0 1 0 0 1 1 1 0 Macoilin family DUF4806 PF16064.5 KLO12717.1 - 0.12 12.7 0.3 0.22 11.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) GvpG PF05120.12 KLO12718.1 - 0.16 12.0 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Gas vesicle protein G Pkinase PF00069.25 KLO12719.1 - 1.2e-69 234.6 0.0 1.5e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12719.1 - 1.1e-52 178.9 0.0 1.5e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO12719.1 - 0.0026 17.1 0.0 0.029 13.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KLO12719.1 - 0.0059 15.4 0.0 0.0074 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PBP_N PF17093.5 KLO12719.1 - 0.069 13.4 0.2 0.19 12.0 0.2 1.8 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus Seadorna_VP7 PF07387.11 KLO12719.1 - 0.11 11.6 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KLO12719.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Fib_alpha PF08702.10 KLO12720.1 - 0.001 19.3 0.5 0.0014 18.8 0.5 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family CorA PF01544.18 KLO12720.1 - 0.0077 15.6 1.0 0.0098 15.2 1.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein IFT57 PF10498.9 KLO12720.1 - 0.02 13.9 0.8 0.025 13.6 0.8 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BicD PF09730.9 KLO12720.1 - 0.021 13.3 0.2 0.026 13.0 0.2 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D NIT PF08376.10 KLO12720.1 - 0.024 15.1 0.1 0.031 14.7 0.1 1.2 1 0 0 1 1 1 0 Nitrate and nitrite sensing Vps54_N PF10475.9 KLO12720.1 - 0.038 13.3 0.3 0.048 13.0 0.3 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Laminin_II PF06009.12 KLO12720.1 - 0.13 12.3 0.8 0.17 11.9 0.8 1.2 1 0 0 1 1 1 0 Laminin Domain II PX PF00787.24 KLO12721.1 - 1.9e-14 53.6 0.1 3.4e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 PX domain Cor1 PF04803.12 KLO12721.1 - 0.15 12.2 2.0 0.28 11.4 2.0 1.4 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Methyltransf_23 PF13489.6 KLO12722.1 - 8.1e-24 84.3 0.0 1.1e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO12722.1 - 3.1e-21 75.8 0.0 5.3e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO12722.1 - 5.6e-17 62.2 0.0 1.1e-16 61.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO12722.1 - 3.1e-15 56.7 0.0 5.7e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO12722.1 - 3.2e-13 49.7 0.0 4.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KLO12722.1 - 5e-09 35.9 0.0 7.2e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KLO12722.1 - 1.9e-06 27.5 0.0 2.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 KLO12722.1 - 6.9e-06 25.2 0.0 1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 KLO12722.1 - 0.00051 19.4 0.0 0.0007 19.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KLO12722.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 KLO12722.1 - 0.0024 17.5 0.0 0.0047 16.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KLO12722.1 - 0.0032 17.1 0.1 0.0092 15.6 0.1 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KLO12722.1 - 0.01 15.9 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 KLO12722.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase TehB PF03848.14 KLO12722.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB ERG4_ERG24 PF01222.17 KLO12723.1 - 2.1e-134 448.6 23.0 2.4e-134 448.4 23.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KLO12723.1 - 4.2e-05 23.2 2.1 0.0001 21.9 2.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KLO12723.1 - 0.1 13.1 2.0 0.19 12.2 0.0 2.4 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Sec10 PF07393.11 KLO12724.1 - 1.9e-117 393.5 0.0 3.2e-112 376.3 0.0 2.3 2 1 0 2 2 2 2 Exocyst complex component Sec10 F-box-like PF12937.7 KLO12724.1 - 0.00016 21.5 0.0 0.00036 20.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO12724.1 - 0.00031 20.5 0.0 0.00073 19.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain Sporozoite_P67 PF05642.11 KLO12724.1 - 0.00032 18.9 1.2 0.00052 18.2 1.2 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen NifU_N PF01592.16 KLO12724.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 NifU-like N terminal domain DUF5337 PF17272.2 KLO12725.1 - 0.85 9.5 7.1 1.9 8.3 0.1 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5337) Aldedh PF00171.22 KLO12727.1 - 6e-14 51.4 2.9 1.4e-11 43.6 0.9 2.4 1 1 1 2 2 2 2 Aldehyde dehydrogenase family SHNi-TPR PF10516.9 KLO12728.1 - 2.2e-18 65.4 0.1 6.8e-16 57.4 0.0 2.8 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 KLO12728.1 - 5.1e-12 45.9 1.0 0.00011 22.4 0.1 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KLO12728.1 - 3.2e-07 29.9 0.1 0.47 10.3 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO12728.1 - 9e-06 25.4 2.0 0.36 11.1 0.3 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KLO12728.1 - 0.0018 18.3 2.9 0.68 10.3 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO12728.1 - 0.005 16.3 0.3 0.47 9.8 0.0 2.7 2 1 1 3 3 3 1 MalT-like TPR region TPR_10 PF13374.6 KLO12728.1 - 0.012 15.5 0.3 2.9 7.9 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KLO12728.1 - 0.016 14.8 3.7 4.2 7.1 0.6 4.5 4 1 0 4 4 4 0 TPR repeat FIN1 PF17300.2 KLO12728.1 - 0.026 14.0 0.4 0.046 13.2 0.4 1.4 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 TPR_16 PF13432.6 KLO12728.1 - 0.051 14.2 4.9 2.5 8.8 4.1 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KLO12728.1 - 0.086 12.9 7.1 5.5 7.3 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat WXG100 PF06013.12 KLO12728.1 - 0.14 12.4 1.9 0.28 11.4 0.1 2.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG FliL PF03748.14 KLO12728.1 - 0.14 12.8 0.8 0.6 10.7 0.3 2.3 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL Prefoldin_2 PF01920.20 KLO12728.1 - 0.2 11.6 4.7 18 5.3 0.0 3.4 3 0 0 3 3 3 0 Prefoldin subunit DASH_Spc19 PF08287.11 KLO12728.1 - 0.94 9.4 7.3 0.32 10.9 3.8 2.0 2 0 0 2 2 2 0 Spc19 TPR_19 PF14559.6 KLO12728.1 - 0.99 10.0 5.8 7.5 7.1 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KLO12728.1 - 1.2 10.1 8.1 36 5.5 0.3 4.3 4 1 1 5 5 4 0 Tetratricopeptide repeat ANTH PF07651.16 KLO12729.1 - 7.2e-52 176.1 0.1 1e-51 175.6 0.1 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KLO12729.1 - 4.8e-05 23.4 0.0 8.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 ENTH domain AP3D1 PF06375.11 KLO12729.1 - 0.06 13.6 1.7 0.15 12.3 1.7 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 WD40 PF00400.32 KLO12730.1 - 9.1e-17 61.1 16.2 1.7e-05 25.5 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO12730.1 - 2.1e-15 56.8 6.9 1.7e-06 28.3 0.1 4.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO12730.1 - 6e-05 22.2 0.1 0.2 10.6 0.1 3.3 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KLO12730.1 - 0.0097 15.8 0.0 19 5.1 0.0 3.1 1 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Thymidylat_synt PF00303.19 KLO12731.1 - 1.1e-104 349.4 0.0 1.2e-104 349.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase JHD PF17811.1 KLO12732.1 - 1.1e-09 38.8 0.0 2.6e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 KLO12732.1 - 1.7e-08 34.9 4.9 2e-08 34.7 0.7 2.9 2 1 0 2 2 2 1 JmjC domain, hydroxylase PHD PF00628.29 KLO12732.1 - 6.4e-07 29.2 7.7 6.4e-07 29.2 7.7 2.2 2 0 0 2 2 2 1 PHD-finger Cupin_8 PF13621.6 KLO12732.1 - 0.00039 20.2 3.8 0.001 18.8 0.1 3.0 2 1 0 2 2 2 1 Cupin-like domain PHD_2 PF13831.6 KLO12732.1 - 0.051 13.1 5.1 0.12 12.0 5.1 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 KLO12732.1 - 0.071 13.0 2.2 0.19 11.7 2.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-CW PF07496.15 KLO12732.1 - 0.095 12.7 8.2 0.34 11.0 8.2 2.0 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_4 PF16866.5 KLO12732.1 - 1.2 9.2 9.3 3.4 7.8 9.3 1.8 1 0 0 1 1 1 0 PHD-finger Pea-VEAacid PF08111.11 KLO12733.1 - 0.054 13.8 0.4 0.93 9.9 0.0 2.9 2 0 0 2 2 2 0 Pea-VEAacid family Paf1 PF03985.13 KLO12734.1 - 2e-72 244.5 0.6 2.4e-72 244.3 0.6 1.0 1 0 0 1 1 1 1 Paf1 CRAL_TRIO PF00650.20 KLO12735.1 - 7.4e-28 97.3 0.0 1e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KLO12735.1 - 1.2e-06 28.6 0.3 3.4e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Methyltransf_15 PF09445.10 KLO12737.1 - 5.5e-33 113.9 0.0 7.9e-32 110.1 0.0 2.1 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KLO12737.1 - 4.9e-06 27.2 0.0 1.1e-05 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KLO12737.1 - 0.00018 21.2 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KLO12737.1 - 0.00033 20.5 0.0 0.00065 19.5 0.0 1.4 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_11 PF08241.12 KLO12737.1 - 0.0049 17.5 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO12737.1 - 0.0068 16.2 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KLO12737.1 - 0.048 13.0 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KLO12737.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DNA_pol3_theta PF06440.11 KLO12737.1 - 0.13 11.9 0.5 0.32 10.7 0.5 1.6 1 0 0 1 1 1 0 DNA polymerase III, theta subunit THOC7 PF05615.13 KLO12740.1 - 7.8e-31 107.1 4.2 7.8e-31 107.1 4.2 1.8 2 0 0 2 2 2 1 Tho complex subunit 7 Biopterin_H PF00351.21 KLO12740.1 - 0.041 12.9 0.3 0.06 12.4 0.3 1.2 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase DAP_B PF07930.12 KLO12740.1 - 0.19 11.7 1.4 0.34 10.9 1.4 1.4 1 0 0 1 1 1 0 D-aminopeptidase, domain B PIN_8 PF18476.1 KLO12740.1 - 0.29 11.0 4.0 0.46 10.3 4.0 1.2 1 0 0 1 1 1 0 PIN like domain Atg14 PF10186.9 KLO12740.1 - 0.41 9.7 6.6 0.62 9.1 6.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 KLO12740.1 - 5.5 4.8 8.3 0.23 9.4 1.7 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Lactamase_B_2 PF12706.7 KLO12741.1 - 4.5e-09 36.1 0.1 0.004 16.7 0.0 3.2 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KLO12741.1 - 3.9e-06 27.0 0.3 1.1e-05 25.5 0.3 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 KLO12741.1 - 7.5e-06 25.5 0.0 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease DnaJ PF00226.31 KLO12743.1 - 4.1e-10 39.6 0.8 7.8e-10 38.7 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain RMI1_N PF08585.12 KLO12744.1 - 1e-34 120.2 0.0 1.2e-34 120.0 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Peptidase_M24 PF00557.24 KLO12745.1 - 9.9e-20 71.1 0.1 1.3e-19 70.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pcc1 PF09341.10 KLO12746.1 - 1.3e-23 83.0 0.5 1.4e-23 82.8 0.5 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 MIF4G PF02854.19 KLO12747.1 - 9.5e-28 97.3 0.1 1.1e-26 93.8 0.1 2.1 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 KLO12747.1 - 2.2e-23 82.4 0.2 6.7e-22 77.6 0.0 2.5 2 0 0 2 2 2 1 MA3 domain Methyltransf_31 PF13847.6 KLO12748.1 - 3.3e-13 49.7 0.0 1.2e-12 47.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO12748.1 - 2.9e-07 31.1 0.0 6.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO12748.1 - 4.7e-07 29.8 0.0 7.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KLO12748.1 - 3.4e-06 27.1 0.0 5.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO12748.1 - 8.8e-06 25.4 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KLO12748.1 - 1.5e-05 25.6 0.0 2.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KLO12748.1 - 0.0012 17.9 0.0 0.0016 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.12 KLO12748.1 - 0.0015 19.2 0.0 0.0037 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KLO12748.1 - 0.012 15.4 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 KLO12748.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 TehB PF03848.14 KLO12748.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.13 KLO12748.1 - 0.026 13.9 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 KLO12748.1 - 0.048 12.6 0.0 0.066 12.2 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_4 PF02390.17 KLO12748.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 KLO12748.1 - 0.073 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 KLO12748.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW N2227 PF07942.12 KLO12748.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Citrate_synt PF00285.21 KLO12750.1 - 1.9e-118 395.6 0.0 2.4e-118 395.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF5121 PF17165.4 KLO12750.1 - 0.073 13.5 0.0 0.23 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5121) APH PF01636.23 KLO12751.1 - 1.2e-05 25.4 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family CtaG_Cox11 PF04442.14 KLO12752.1 - 9.3e-56 188.0 0.1 1.8e-55 187.1 0.1 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 PH PF00169.29 KLO12752.1 - 0.0004 20.9 0.0 0.05 14.1 0.0 3.0 3 0 0 3 3 3 1 PH domain FAM176 PF14851.6 KLO12752.1 - 0.77 9.4 2.9 3.5 7.3 2.9 2.2 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 KLO12752.1 - 3.7 5.5 9.2 7.6 4.5 9.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 KLO12752.1 - 5.3 7.5 18.5 12 6.4 18.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 KLO12752.1 - 5.9 6.6 6.9 21 4.8 6.9 1.9 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SNARE_assoc PF09335.11 KLO12753.1 - 3.1e-10 40.6 8.0 3.1e-10 40.6 8.0 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein ARID PF01388.21 KLO12755.1 - 8.7e-13 48.8 0.3 3.9e-12 46.7 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Med15_fungi PF05397.12 KLO12755.1 - 0.004 17.4 6.6 0.004 17.4 6.6 3.4 3 1 1 4 4 4 1 Mediator complex subunit 15 Dehydrin PF00257.19 KLO12755.1 - 0.031 14.8 5.6 0.12 12.9 5.6 2.2 1 0 0 1 1 1 0 Dehydrin SRP1_TIP1 PF00660.17 KLO12755.1 - 0.06 13.4 0.0 0.23 11.6 0.0 2.0 1 0 0 1 1 1 0 Seripauperin and TIP1 family DUF5427 PF10310.9 KLO12755.1 - 8.7 5.2 16.1 19 4.1 16.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Chloroa_b-bind PF00504.21 KLO12757.1 - 0.21 12.1 0.0 0.36 11.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyll A-B binding protein DUF2569 PF10754.9 KLO12757.1 - 0.58 10.6 14.2 1.2 9.5 0.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2569) Ac76 PF05814.11 KLO12757.1 - 1.1 9.3 3.9 3.1 7.9 0.0 2.8 3 0 0 3 3 3 0 Orf76 (Ac76) Otopetrin PF03189.13 KLO12760.1 - 0.053 12.3 2.4 0.17 10.6 0.2 2.2 2 0 0 2 2 2 0 Otopetrin zf-C3HC4_3 PF13920.6 KLO12762.1 - 1.5e-07 31.1 10.0 3.7e-07 29.9 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KLO12762.1 - 5.8e-06 26.2 9.5 5.8e-06 26.2 9.5 4.2 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH PF00642.24 KLO12762.1 - 0.00035 20.4 27.1 0.0018 18.1 3.9 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.25 KLO12762.1 - 0.00035 20.4 11.4 0.00079 19.2 11.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO12762.1 - 0.0011 19.2 11.6 0.0011 19.2 11.6 2.6 2 0 0 2 2 2 1 Ring finger domain Torus PF16131.5 KLO12762.1 - 0.0016 19.1 13.9 0.16 12.6 1.6 3.5 2 1 1 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 KLO12762.1 - 0.003 17.3 6.8 0.003 17.3 6.8 3.7 3 0 0 3 3 3 1 CCCH-type zinc finger zf-RING_5 PF14634.6 KLO12762.1 - 0.011 15.7 10.8 0.036 14.0 10.8 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KLO12762.1 - 0.36 10.9 11.6 0.25 11.4 9.3 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 KLO12762.1 - 0.37 11.1 6.4 1 9.7 6.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KLO12762.1 - 3.2 7.7 14.0 1.7 8.5 9.9 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 HMGL-like PF00682.19 KLO12763.1 - 1e-78 264.6 0.3 1.4e-78 264.1 0.3 1.2 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.6 KLO12763.1 - 0.086 13.4 0.3 0.16 12.5 0.3 1.4 1 0 0 1 1 1 0 FliG N-terminal domain RNase_T PF00929.24 KLO12764.1 - 0.00017 22.2 0.0 0.00027 21.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease TMF_TATA_bd PF12325.8 KLO12764.1 - 0.2 11.9 3.4 0.71 10.1 0.0 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding RNase_T PF00929.24 KLO12765.1 - 0.0051 17.4 0.0 0.0076 16.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Pom PF17251.2 KLO12767.1 - 0.14 11.5 3.3 0.12 11.7 1.9 1.5 2 0 0 2 2 2 0 Protochlamydia outer membrane protein Caps_synth_CapC PF14102.6 KLO12767.1 - 2.1 8.8 6.5 0.22 11.9 0.6 2.3 2 1 1 3 3 3 0 Capsule biosynthesis CapC MOZ_SAS PF01853.18 KLO12768.1 - 2.2e-67 226.2 0.0 3e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KLO12768.1 - 7.5e-22 76.7 0.6 7.5e-22 76.7 0.6 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 KLO12768.1 - 0.064 13.3 0.2 0.064 13.3 0.2 2.0 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger PHD PF00628.29 KLO12769.1 - 2.5e-05 24.1 7.7 2.5e-05 24.1 7.7 2.0 1 1 1 2 2 2 1 PHD-finger zf-CCHC PF00098.23 KLO12769.1 - 0.065 13.3 0.7 0.065 13.3 0.7 2.8 2 1 0 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 KLO12769.1 - 0.66 10.1 12.8 0.14 12.3 5.5 2.1 1 1 1 2 2 2 0 PHD-finger Pkinase_Tyr PF07714.17 KLO12770.1 - 1.2e-39 136.2 0.0 1.5e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO12770.1 - 7.4e-37 127.1 0.0 9.4e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO12770.1 - 8.3e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO12770.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KLO12770.1 - 0.097 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KLO12771.1 - 6.9e-12 45.3 0.0 9.3e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12771.1 - 1.5e-11 44.1 0.0 2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Cu-oxidase_3 PF07732.15 KLO12772.1 - 0.21 11.6 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 Multicopper oxidase Pkinase PF00069.25 KLO12774.1 - 3.7e-47 160.9 0.0 1.1e-46 159.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12774.1 - 2.2e-17 63.2 0.0 3.6e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KLO12774.1 - 0.13 11.9 0.2 0.36 10.4 0.1 1.7 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 KLO12774.1 - 0.14 12.1 0.8 0.65 9.9 0.6 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Hydantoinase_A PF01968.18 KLO12776.1 - 0.048 12.9 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Peripla_BP_2 PF01497.18 KLO12778.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein RE_HaeIII PF09556.10 KLO12782.1 - 0.067 12.3 0.0 0.081 12.0 0.0 1.0 1 0 0 1 1 1 0 HaeIII restriction endonuclease DUF4687 PF15747.5 KLO12784.1 - 0.58 10.7 6.8 0.17 12.4 3.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4687) PSK_trans_fac PF07704.11 KLO12788.1 - 0.12 13.1 2.1 0.8 10.5 0.1 2.6 3 0 0 3 3 3 0 Rv0623-like transcription factor MarB PF13999.6 KLO12790.1 - 0.097 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 MarB protein Transposase_21 PF02992.14 KLO12794.1 - 0.00038 19.8 0.0 0.00061 19.1 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 KLO12795.1 - 9.4e-06 25.2 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Asp PF00026.23 KLO12797.1 - 7.7e-67 225.9 6.0 9.7e-67 225.6 6.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO12797.1 - 3.9e-09 37.0 4.5 2e-08 34.7 1.6 2.8 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal CS PF04969.16 KLO12799.1 - 6.2e-07 30.4 0.0 1.1e-06 29.5 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 KLO12799.1 - 0.077 13.1 1.4 0.2 11.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.12 KLO12799.1 - 0.2 12.4 0.8 13 6.7 0.0 3.0 3 0 0 3 3 3 0 Sel1 repeat MAS20 PF02064.15 KLO12799.1 - 0.62 10.2 3.0 1.4 9.0 0.0 2.7 3 0 0 3 3 3 0 MAS20 protein import receptor Pkinase PF00069.25 KLO12801.1 - 1.7e-62 211.2 0.0 2.4e-41 141.8 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12801.1 - 1.4e-27 96.6 0.0 1.8e-22 79.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KLO12801.1 - 8.2e-14 51.7 0.0 1.9e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KLO12801.1 - 6.9e-09 35.4 0.0 0.00011 21.6 0.0 2.5 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 KLO12801.1 - 0.00047 19.8 0.0 0.25 10.9 0.0 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KLO12801.1 - 0.00053 20.0 0.1 0.0031 17.5 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family PAS_9 PF13426.7 KLO12801.1 - 0.0051 17.0 0.0 0.019 15.2 0.0 2.0 1 0 0 1 1 1 1 PAS domain Haspin_kinase PF12330.8 KLO12801.1 - 0.0076 15.2 1.3 0.0085 15.1 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KLO12801.1 - 0.0079 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KLO12801.1 - 0.024 13.7 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KLO12801.1 - 0.031 13.9 0.1 0.069 12.7 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KLO12801.1 - 9.4 4.9 8.0 0.31 9.8 0.1 2.5 3 0 0 3 3 3 0 Fungal protein kinase Abhydrolase_1 PF00561.20 KLO12802.1 - 1e-24 87.6 0.0 1.7e-24 86.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO12802.1 - 1.6e-18 66.9 0.0 1.1e-14 54.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KLO12802.1 - 2.8e-15 57.5 0.0 7.4e-15 56.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KLO12802.1 - 6.7e-05 22.6 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Esterase PF00756.20 KLO12802.1 - 0.00012 21.8 0.1 0.00024 20.8 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KLO12802.1 - 0.00049 20.0 0.0 0.014 15.2 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KLO12802.1 - 0.00049 20.1 0.0 0.25 11.2 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Ndr PF03096.14 KLO12802.1 - 0.0035 16.1 0.0 0.0061 15.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.13 KLO12802.1 - 0.0048 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Lipase_3 PF01764.25 KLO12802.1 - 0.028 14.3 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_4 PF08386.10 KLO12802.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF915 PF06028.11 KLO12802.1 - 0.13 11.5 0.0 0.4 10.0 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.18 KLO12802.1 - 0.16 11.5 0.0 1.7 8.1 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Pkinase_Tyr PF07714.17 KLO12803.1 - 8.4e-47 159.6 0.0 1.2e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO12803.1 - 4.7e-33 114.7 0.0 7e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO12803.1 - 0.0072 16.3 0.2 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KLO12803.1 - 0.048 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO12803.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Forkhead PF00250.18 KLO12804.1 - 3.9e-25 87.9 0.0 6.6e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KLO12804.1 - 1.3e-07 31.9 0.0 2.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain MT-A70 PF05063.14 KLO12805.1 - 4.9e-57 192.6 0.0 6.4e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 MT-A70 DUF2298 PF10060.9 KLO12806.1 - 0.18 10.5 0.3 0.22 10.2 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Stevor PF17410.2 KLO12806.1 - 0.18 11.3 1.9 0.27 10.8 1.9 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Macoilin PF09726.9 KLO12806.1 - 0.23 10.0 8.2 0.28 9.7 8.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF572 PF04502.13 KLO12806.1 - 6.7 6.2 10.5 8.9 5.8 10.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) adh_short PF00106.25 KLO12807.1 - 1.9e-15 56.9 0.0 2.6e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO12807.1 - 7.5e-09 35.5 0.0 9.5e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO12807.1 - 0.00061 19.8 0.0 0.00089 19.2 0.0 1.2 1 0 0 1 1 1 1 KR domain ARS2 PF04959.13 KLO12808.1 - 8 6.8 8.8 8.7 6.7 8.0 1.4 1 1 0 1 1 1 0 Arsenite-resistance protein 2 Mei5 PF10376.9 KLO12809.1 - 8.8 6.1 9.0 82 3.0 9.0 2.4 1 1 0 1 1 1 0 Double-strand recombination repair protein AAA PF00004.29 KLO12810.1 - 1.9e-31 109.2 0.0 3.3e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO12810.1 - 7.9e-08 32.7 0.1 8.5e-07 29.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO12810.1 - 2e-06 28.3 0.2 1.3e-05 25.7 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 KLO12810.1 - 2.6e-05 24.4 0.0 5.1e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KLO12810.1 - 3.2e-05 24.5 0.0 6.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KLO12810.1 - 5.4e-05 23.4 0.0 0.00015 22.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KLO12810.1 - 5.6e-05 23.4 0.0 0.00013 22.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KLO12810.1 - 6.9e-05 22.9 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KLO12810.1 - 0.00013 21.7 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KLO12810.1 - 0.00066 19.7 0.1 0.84 9.5 0.1 2.3 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KLO12810.1 - 0.00078 19.5 0.1 0.0016 18.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KLO12810.1 - 0.00098 19.1 0.1 0.0032 17.4 0.1 1.9 1 1 0 1 1 1 1 NACHT domain RuvB_N PF05496.12 KLO12810.1 - 0.001 18.9 0.1 0.0043 16.8 0.1 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KLO12810.1 - 0.0013 19.0 0.0 0.0034 17.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 KLO12810.1 - 0.0014 18.6 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KLO12810.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 KLO12810.1 - 0.0015 18.3 0.4 0.0038 17.0 0.1 2.0 2 1 0 2 2 2 1 Cytidylate kinase AAA_11 PF13086.6 KLO12810.1 - 0.0017 18.2 0.1 0.0039 17.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KLO12810.1 - 0.002 17.4 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain PduV-EutP PF10662.9 KLO12810.1 - 0.0038 17.0 0.0 0.0072 16.1 0.0 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 KLO12810.1 - 0.0043 17.0 0.0 0.0094 15.9 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_25 PF13481.6 KLO12810.1 - 0.0069 16.0 0.1 0.24 10.9 0.0 2.2 1 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KLO12810.1 - 0.0077 16.0 0.0 0.026 14.2 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 KLO12810.1 - 0.0078 16.0 0.0 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KLO12810.1 - 0.014 14.5 0.0 0.21 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 KLO12810.1 - 0.024 15.0 0.2 0.17 12.3 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KLO12810.1 - 0.025 14.1 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DnaB_C PF03796.15 KLO12810.1 - 0.032 13.5 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ABC_tran PF00005.27 KLO12810.1 - 0.047 14.2 0.0 0.092 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 KLO12810.1 - 0.07 12.5 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KLO12810.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KLO12810.1 - 0.12 12.8 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 KLO12810.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.26 KLO12810.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PPR_3 PF13812.6 KLO12811.1 - 2e-06 27.8 0.1 0.054 13.6 0.0 3.0 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KLO12811.1 - 0.05 13.8 2.7 8.8 6.6 0.0 3.4 4 0 0 4 4 4 0 PPR repeat family TPMT PF05724.11 KLO12812.1 - 8.6e-35 120.4 0.0 1.1e-34 120.1 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KLO12812.1 - 2.9e-10 40.7 0.0 4.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO12812.1 - 3.8e-09 37.1 0.0 5.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO12812.1 - 4.8e-08 33.0 0.0 6.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO12812.1 - 4.1e-07 29.9 0.0 6.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO12812.1 - 6.8e-07 30.0 0.0 1.1e-06 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KLO12812.1 - 0.00066 19.1 0.0 0.00085 18.8 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 KLO12812.1 - 0.033 13.7 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain N2227 PF07942.12 KLO12812.1 - 0.059 12.5 0.1 5.2 6.2 0.0 2.1 1 1 1 2 2 2 0 N2227-like protein TPMT PF05724.11 KLO12813.1 - 4.6e-41 140.9 0.0 5.7e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KLO12813.1 - 6.6e-10 39.6 0.0 1.1e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO12813.1 - 1.1e-09 38.3 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO12813.1 - 3.2e-08 34.1 0.0 5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO12813.1 - 3.2e-06 27.1 0.0 4.5e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO12813.1 - 7.9e-06 26.5 0.0 1.3e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO12813.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 KLO12813.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KLO12813.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase N2227 PF07942.12 KLO12813.1 - 0.2 10.8 0.2 2.2 7.4 0.0 2.0 1 1 1 2 2 2 0 N2227-like protein HSF_DNA-bind PF00447.17 KLO12816.1 - 8.6e-14 51.9 0.0 1.4e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Pkinase PF00069.25 KLO12817.1 - 6.3e-72 242.1 0.0 8.3e-72 241.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12817.1 - 3.4e-30 105.2 0.0 6.2e-22 78.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KLO12817.1 - 4.3e-09 36.1 0.3 0.054 12.8 0.1 3.3 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KLO12817.1 - 0.0065 15.3 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO12817.1 - 0.007 16.3 0.0 0.28 11.1 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KLO12817.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KLO12817.1 - 0.074 12.0 0.0 1.2 8.0 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain SNARE_assoc PF09335.11 KLO12818.1 - 6e-15 55.8 6.6 5.5e-14 52.7 7.5 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein MerE PF05052.12 KLO12818.1 - 0.0054 16.6 0.7 0.0054 16.6 0.7 2.0 2 0 0 2 2 2 1 MerE protein SpoIIIAH PF12685.7 KLO12818.1 - 0.052 13.4 0.0 0.073 12.9 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2076 PF09849.9 KLO12819.1 - 0.52 10.3 7.1 0.13 12.2 1.8 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) PEX11 PF05648.14 KLO12820.1 - 8e-12 45.1 2.7 8.4e-06 25.4 0.4 2.9 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Tctex-1 PF03645.13 KLO12821.1 - 2.2e-09 37.5 0.1 3.1e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family MFS_1 PF07690.16 KLO12822.1 - 6.6e-23 81.2 45.6 6.4e-18 64.8 11.9 3.4 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO12822.1 - 4.7e-07 29.0 6.0 4.7e-07 29.0 6.0 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KLO12822.1 - 2.8e-06 26.0 9.2 0.0025 16.3 1.0 2.4 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3784 PF12650.7 KLO12822.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3784) COA2 PF17051.5 KLO12823.1 - 8.5e-07 28.9 0.0 9.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Ribosomal_S14 PF00253.21 KLO12824.1 - 6.1e-23 80.3 0.2 8.8e-23 79.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF3425 PF11905.8 KLO12825.1 - 2.5e-13 50.1 0.1 1.8e-12 47.3 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KLO12825.1 - 3.1e-08 33.6 9.6 2.1e-07 30.9 9.6 2.2 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KLO12825.1 - 0.0023 18.0 12.5 0.015 15.3 5.9 2.5 1 1 1 2 2 2 2 Basic region leucine zipper TTRAP PF14203.6 KLO12825.1 - 0.067 13.2 0.9 0.13 12.3 0.9 1.4 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein DUF5101 PF17031.5 KLO12825.1 - 0.11 12.6 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) Shugoshin_N PF07558.11 KLO12825.1 - 0.14 12.0 1.4 2.1 8.3 0.3 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region bZIP_Maf PF03131.17 KLO12825.1 - 0.95 10.0 8.0 0.2 12.2 4.4 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor DNA_RNApol_7kD PF03604.13 KLO12827.1 - 1.5e-16 59.7 4.9 2e-16 59.3 4.9 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit MCM_OB PF17207.3 KLO12827.1 - 0.0068 16.3 0.6 0.0086 15.9 0.6 1.1 1 0 0 1 1 1 1 MCM OB domain C1_1 PF00130.22 KLO12827.1 - 0.026 14.4 0.7 0.046 13.6 0.7 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC PF07967.13 KLO12827.1 - 0.04 13.9 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like HypA PF01155.19 KLO12827.1 - 0.041 13.9 0.1 0.048 13.7 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KLO12827.1 - 0.049 13.4 0.2 0.049 13.4 0.2 1.9 2 1 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KLO12827.1 - 0.061 13.1 3.9 2.8 7.7 0.2 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain Zn_ribbon_recom PF13408.6 KLO12827.1 - 0.079 13.5 2.5 0.78 10.3 0.2 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.10 KLO12827.1 - 0.088 12.9 3.6 0.16 12.1 2.8 1.9 1 1 1 2 2 2 0 Zinc ribbon domain DZR PF12773.7 KLO12827.1 - 0.13 12.3 4.9 0.34 11.0 4.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 KLO12827.1 - 0.55 9.9 3.0 11 5.7 0.1 2.5 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Mss51 PF13824.6 KLO12827.1 - 1 9.5 4.0 1.2 9.3 0.5 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HYPF PF07503.12 KLO12827.1 - 1.2 9.0 7.4 6 6.7 0.1 2.9 2 1 1 3 3 3 0 HypF finger zf-trcl PF13451.6 KLO12827.1 - 1.5 8.8 5.6 12 5.9 1.1 2.2 1 1 1 2 2 2 0 Probable zinc-ribbon domain RRM_1 PF00076.22 KLO12829.1 - 2.9e-26 91.1 0.0 9.2e-14 51.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.6 KLO12829.1 - 2.1e-22 78.7 1.3 5.1e-22 77.4 1.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KLO12829.1 - 1e-06 28.5 1.3 3.7e-06 26.7 0.3 2.3 2 0 0 2 2 2 1 G-patch domain DbpA PF03880.15 KLO12829.1 - 0.065 13.2 0.1 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain OB_RNB PF08206.11 KLO12829.1 - 5.1 6.8 6.1 3.7 7.3 0.0 3.1 4 0 0 4 4 4 0 Ribonuclease B OB domain LRR_4 PF12799.7 KLO12830.1 - 0.0084 16.5 0.5 6.8 7.3 0.2 4.0 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) Dicer_dimer PF03368.14 KLO12830.1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Dicer dimerisation domain Glyco_hydro_cc PF11790.8 KLO12831.1 - 2.1e-58 197.8 0.6 2.8e-58 197.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Hamartin PF04388.12 KLO12831.1 - 3.3 6.2 6.9 4.4 5.8 6.9 1.1 1 0 0 1 1 1 0 Hamartin protein Apt1 PF10351.9 KLO12831.1 - 5.6 5.7 6.3 6.9 5.4 6.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KLO12831.1 - 7.4 5.0 6.4 8.4 4.8 6.4 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_cc PF11790.8 KLO12832.1 - 1.8e-60 204.5 6.0 2.3e-60 204.1 6.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Serglycin PF04360.12 KLO12832.1 - 0.047 13.6 1.3 0.084 12.8 0.8 1.7 2 0 0 2 2 2 0 Serglycin P3A PF08727.11 KLO12833.1 - 0.089 12.2 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Poliovirus 3A protein like Ribosomal_L11 PF00298.19 KLO12836.1 - 4.2e-29 100.9 0.2 7.2e-29 100.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KLO12836.1 - 2.5e-24 84.9 0.5 5e-24 83.9 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Peptidase_M28 PF04389.17 KLO12837.1 - 4.4e-27 95.1 0.1 7.1e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KLO12837.1 - 3.3e-08 33.5 0.0 4.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KLO12838.1 - 0.00015 22.5 0.5 0.11 13.4 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Cadherin_tail PF15974.5 KLO12839.1 - 0.015 15.6 2.9 0.046 14.1 2.9 1.7 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region WD40 PF00400.32 KLO12840.1 - 2.4e-05 25.0 7.8 0.13 13.2 1.5 3.9 4 1 0 4 4 4 3 WD domain, G-beta repeat DUF2373 PF10180.9 KLO12841.1 - 8.2e-16 57.6 0.3 4.8e-07 29.5 0.2 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) FAM60A PF15396.6 KLO12841.1 - 3.2 7.7 14.5 1.4 8.8 11.5 1.9 2 0 0 2 2 2 0 Protein Family FAM60A GREB1 PF15782.5 KLO12841.1 - 3.6 4.6 9.3 4.4 4.3 9.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Arf PF00025.21 KLO12842.1 - 1e-68 230.2 0.0 1.2e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KLO12842.1 - 2.4e-12 47.1 0.0 3.4e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KLO12842.1 - 1.1e-11 44.5 0.1 6.4e-06 25.6 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KLO12842.1 - 1.9e-11 43.8 0.0 2.3e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KLO12842.1 - 8.5e-10 38.4 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KLO12842.1 - 2.2e-07 30.5 0.0 2.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KLO12842.1 - 0.0029 17.6 0.0 0.0048 17.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase WD40 PF00400.32 KLO12843.1 - 2.5e-22 78.8 13.6 3.5e-06 27.6 1.2 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO12843.1 - 3.8e-11 43.1 0.1 1.3e-08 35.0 0.1 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2387 PF09526.10 KLO12843.1 - 0.042 14.0 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Iso_dh PF00180.20 KLO12844.1 - 1.3e-97 327.1 0.0 1.6e-97 326.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase F-box-like PF12937.7 KLO12845.1 - 0.024 14.5 0.1 0.085 12.8 0.1 2.0 1 0 0 1 1 1 0 F-box-like Flavokinase PF01687.17 KLO12846.1 - 1.2e-30 106.1 0.0 1.5e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase RRM_1 PF00076.22 KLO12847.1 - 1.3e-12 47.3 0.0 1.7e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KLO12847.1 - 0.091 12.9 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif cwf21 PF08312.12 KLO12848.1 - 4.2e-14 52.4 13.5 4.2e-14 52.4 13.5 2.3 2 1 0 2 2 2 1 cwf21 domain Aminotran_1_2 PF00155.21 KLO12849.1 - 2.2e-76 257.4 0.0 2.9e-76 257.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KLO12849.1 - 7.6e-05 21.4 0.0 0.00012 20.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KLO12849.1 - 0.00017 20.7 0.0 0.00029 19.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Pertussis_S1 PF02917.14 KLO12849.1 - 0.027 14.3 0.1 0.087 12.6 0.0 1.9 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 zf-CCCH_6 PF18585.1 KLO12849.1 - 0.16 11.9 0.2 11 6.0 0.0 3.3 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Aminotran_3 PF00202.21 KLO12850.1 - 3.8e-96 322.2 0.0 1.1e-95 320.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KLO12850.1 - 0.0096 15.1 0.0 0.021 14.0 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Glyco_hydro_125 PF06824.11 KLO12852.1 - 1.4e-137 459.0 0.1 1.6e-137 458.8 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) C2 PF00168.30 KLO12853.1 - 8.2e-13 48.5 0.0 4.5e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain NUFIP1 PF10453.9 KLO12854.1 - 0.013 15.3 0.8 0.028 14.3 0.8 1.5 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) O_anti_polymase PF01901.16 KLO12855.1 - 0.053 12.8 0.1 0.077 12.2 0.1 1.2 1 0 0 1 1 1 0 Putative O-antigen polymerase Pedibin PF08182.11 KLO12855.1 - 0.054 13.3 0.2 0.38 10.6 0.1 2.3 2 0 0 2 2 2 0 Pedibin/Hym-346 family Cnl2_NKP2 PF09447.10 KLO12855.1 - 0.13 12.4 2.8 7.2 6.8 0.1 3.6 4 0 0 4 4 4 0 Cnl2/NKP2 family protein LRR_9 PF14580.6 KLO12855.1 - 0.51 9.8 2.4 10 5.6 0.0 2.9 3 0 0 3 3 3 0 Leucine-rich repeat Myb_DNA-binding PF00249.31 KLO12857.1 - 7.4e-37 125.3 6.5 9.2e-10 38.6 0.0 5.4 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KLO12857.1 - 4e-31 107.0 4.3 8.3e-11 42.0 0.1 5.2 3 2 2 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 KLO12857.1 - 0.082 12.9 0.0 2.4 8.2 0.0 3.1 2 1 1 3 3 3 0 SLIDE MADF_DNA_bdg PF10545.9 KLO12857.1 - 0.6 10.5 8.2 2.1 8.7 0.1 4.1 5 0 0 5 5 5 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TAF8_C PF10406.9 KLO12858.1 - 1.3e-09 38.5 7.3 3e-09 37.3 7.3 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KLO12858.1 - 8.2e-07 28.9 0.1 1.4e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TMEM208_SND2 PF05620.11 KLO12859.1 - 3.2e-51 173.4 0.1 3.6e-51 173.3 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 P120R PF08062.11 KLO12859.1 - 0.13 12.6 1.0 0.13 12.6 1.0 1.7 2 0 0 2 2 2 0 P120R (NUC006) repeat Rdx PF10262.9 KLO12860.1 - 6.4e-24 83.9 0.0 8.8e-24 83.5 0.0 1.2 1 0 0 1 1 1 1 Rdx family Peptidase_C48 PF02902.19 KLO12861.1 - 9e-14 51.8 0.0 1.5e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain NAD_binding_8 PF13450.6 KLO12863.1 - 1.1e-12 47.9 0.0 3.2e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO12863.1 - 1.9e-10 40.9 0.0 1.9e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO12863.1 - 6.3e-07 28.9 0.0 0.00012 21.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO12863.1 - 2.2e-06 28.1 0.0 0.056 14.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KLO12863.1 - 4e-06 26.4 0.0 1.5e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KLO12863.1 - 4.1e-06 25.8 0.3 0.0051 15.6 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 KLO12863.1 - 4.7e-05 23.4 0.0 0.00093 19.2 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KLO12863.1 - 4.9e-05 22.7 0.0 0.00011 21.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KLO12863.1 - 7.3e-05 22.3 0.0 0.00099 18.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO12863.1 - 0.00035 19.8 0.0 0.00052 19.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain MCRA PF06100.11 KLO12863.1 - 0.0062 15.4 0.2 0.69 8.6 0.0 2.1 2 0 0 2 2 2 2 MCRA family K_oxygenase PF13434.6 KLO12863.1 - 0.01 15.0 0.0 1 8.4 0.0 2.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KLO12863.1 - 0.017 14.2 0.3 0.042 12.9 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KLO12863.1 - 0.019 14.2 0.0 0.67 9.1 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KLO12863.1 - 0.035 13.0 0.5 0.18 10.7 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KLO12863.1 - 0.036 13.3 0.2 0.25 10.5 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KLO12863.1 - 0.058 12.9 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KLO12863.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 KLO12863.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KLO12865.1 - 7.6e-19 68.1 0.1 2.3e-18 66.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KLO12865.1 - 8.2e-16 58.4 0.4 1.4e-15 57.7 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KLO12865.1 - 1.1e-11 44.3 0.0 4.1e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KLO12865.1 - 5.2e-09 36.0 0.5 2.7e-08 33.7 0.3 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 KLO12865.1 - 1.2e-08 34.5 0.0 1.7e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KLO12865.1 - 2.6e-07 30.4 0.0 4.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KLO12865.1 - 3.5e-05 23.1 0.0 8.8e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KLO12865.1 - 0.0027 17.2 0.1 0.037 13.5 0.3 2.6 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KLO12865.1 - 0.0043 16.2 0.1 3.7 6.6 0.0 3.1 2 1 0 2 2 2 2 RmlD substrate binding domain DFP PF04127.15 KLO12865.1 - 0.018 14.9 0.1 0.061 13.1 0.0 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein KR PF08659.10 KLO12865.1 - 0.33 10.8 1.5 16 5.4 1.5 2.2 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 KLO12866.1 - 9.3e-19 67.8 0.0 4.1e-18 65.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KLO12866.1 - 1.1e-14 54.7 1.9 1.2e-14 54.7 0.8 1.5 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KLO12866.1 - 3.8e-13 49.1 0.0 5.5e-12 45.3 0.0 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KLO12866.1 - 4.6e-08 32.9 1.2 1.3e-07 31.4 1.0 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 KLO12866.1 - 9.7e-08 31.5 0.0 0.00071 18.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KLO12866.1 - 3.2e-06 26.5 0.0 0.00019 20.6 0.2 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KLO12866.1 - 7.2e-05 22.3 0.2 0.00019 21.0 0.1 1.8 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KLO12866.1 - 0.029 13.8 0.2 0.11 11.9 0.2 2.2 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KLO12866.1 - 0.073 12.2 0.1 1.5 7.9 0.1 2.7 3 0 0 3 3 3 0 RmlD substrate binding domain Fungal_trans PF04082.18 KLO12867.1 - 2.1e-06 27.0 0.0 4.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MAR_sialic_bdg PF10564.9 KLO12867.1 - 0.021 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat Fungal_trans PF04082.18 KLO12869.1 - 3e-11 42.9 0.0 5.4e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KLO12870.1 - 3.2e-08 32.9 0.4 5.5e-08 32.2 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO12871.1 - 1.4e-06 28.3 8.9 2.3e-06 27.6 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro-kuma_activ PF09286.11 KLO12872.1 - 8.4e-37 126.6 0.0 2.1e-36 125.3 0.0 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KLO12872.1 - 0.00072 18.9 2.2 0.001 18.4 1.5 1.6 2 0 0 2 2 2 1 Subtilase family adh_short_C2 PF13561.6 KLO12873.1 - 1.2e-53 182.1 0.1 1.5e-53 181.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO12873.1 - 2.4e-50 170.7 0.2 9.8e-50 168.7 0.3 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KLO12873.1 - 5.6e-14 52.4 0.6 1.6e-13 51.0 0.4 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KLO12873.1 - 7.2e-09 35.5 0.1 3.5e-08 33.2 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO12873.1 - 0.00011 21.7 0.1 0.00018 21.0 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KLO12873.1 - 0.0065 16.4 2.0 0.011 15.7 2.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KLO12873.1 - 0.0093 15.1 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KLO12873.1 - 0.019 14.6 1.2 0.033 13.7 1.2 1.4 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.18 KLO12873.1 - 0.031 14.2 0.3 0.057 13.3 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KLO12873.1 - 0.056 12.4 0.1 0.079 11.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PSY3 PF16836.5 KLO12873.1 - 0.11 12.0 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description Sterol_MT_C PF08498.10 KLO12876.1 - 3.8e-28 97.6 0.2 6.1e-28 96.9 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KLO12876.1 - 7.4e-19 68.2 0.0 1.7e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO12876.1 - 3e-18 66.1 0.0 7.9e-18 64.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO12876.1 - 2.6e-17 63.3 0.0 6.4e-17 62.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO12876.1 - 1.7e-13 51.2 0.0 3.8e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KLO12876.1 - 3.5e-13 49.5 0.0 4.6e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KLO12876.1 - 5e-12 46.0 0.0 8.6e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO12876.1 - 1.6e-08 34.2 0.0 3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KLO12876.1 - 0.00015 21.5 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 KLO12876.1 - 0.00017 20.8 0.0 0.00027 20.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.14 KLO12876.1 - 0.00035 20.2 0.0 0.00067 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KLO12876.1 - 0.00038 20.1 0.0 0.00063 19.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.10 KLO12876.1 - 0.00073 19.1 0.1 0.0011 18.6 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.6 KLO12876.1 - 0.0016 19.4 0.0 0.007 17.4 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KLO12876.1 - 0.0052 16.1 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain UPF0020 PF01170.18 KLO12876.1 - 0.031 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Spermine_synth PF01564.17 KLO12876.1 - 0.054 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase domain PrmA PF06325.13 KLO12876.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KLO12876.1 - 0.17 11.9 0.0 0.41 10.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Aldo_ket_red PF00248.21 KLO12877.1 - 1e-47 162.8 0.0 2.6e-47 161.4 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.19 KLO12878.1 - 5e-16 58.9 0.0 1.6e-15 57.3 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO12878.1 - 4.9e-14 53.1 0.1 1.6e-13 51.4 0.1 2.0 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KLO12878.1 - 4.9e-07 29.7 0.4 0.0014 18.3 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO12878.1 - 1.1e-05 25.6 0.2 3.4e-05 24.0 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KLO12878.1 - 1.2e-05 24.6 0.7 6.5e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO12878.1 - 5.7e-05 22.5 0.0 0.0012 18.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KLO12878.1 - 0.00015 21.1 0.3 0.00023 20.5 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KLO12878.1 - 0.00031 20.2 0.2 0.0037 16.7 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KLO12878.1 - 0.00045 19.0 0.0 0.0011 17.8 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KLO12878.1 - 0.0012 18.2 0.0 0.024 13.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO12878.1 - 0.02 14.2 0.1 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KLO12878.1 - 0.047 12.7 0.1 0.075 12.1 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GMC_oxred_C PF05199.13 KLO12879.1 - 1.5e-13 51.5 0.1 4.1e-13 50.1 0.1 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KLO12879.1 - 5.7e-11 42.3 0.0 4.8e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.24 KLO12879.1 - 3.6e-07 30.1 0.2 0.00078 19.1 0.3 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO12879.1 - 8.5e-06 25.9 0.2 2.7e-05 24.3 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KLO12879.1 - 3.6e-05 23.0 0.3 9.3e-05 21.7 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KLO12879.1 - 9.5e-05 21.8 0.2 0.00014 21.2 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO12879.1 - 0.00028 20.2 0.1 0.00073 18.9 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO12879.1 - 0.00029 19.7 0.0 0.00055 18.8 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KLO12879.1 - 0.0021 17.4 0.2 0.0051 16.1 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KLO12879.1 - 0.018 14.4 0.1 0.06 12.7 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KLO12879.1 - 0.031 13.3 0.1 0.053 12.6 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KLO12879.1 - 0.043 13.1 0.1 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 Thi4 family DUF1761 PF08570.10 KLO12880.1 - 0.0074 16.5 0.4 3.2 8.0 0.5 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1761) Exc PF07825.11 KLO12881.1 - 0.11 12.5 0.7 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Excisionase-like protein Pkinase PF00069.25 KLO12884.1 - 5.6e-44 150.5 0.0 7.3e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12884.1 - 3.4e-41 141.2 0.0 4.5e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO12884.1 - 0.034 13.4 0.0 0.2 10.9 0.0 2.0 1 1 0 1 1 1 0 Kinase-like WD40 PF00400.32 KLO12885.1 - 3.1e-19 69.0 0.9 6e-07 30.1 0.2 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO12885.1 - 0.0014 18.9 0.0 0.0065 16.7 0.0 2.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO12885.1 - 0.045 12.7 0.0 0.49 9.3 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KLO12885.1 - 0.056 12.0 0.1 5.7 5.4 0.0 2.8 2 2 1 3 3 3 0 Cytochrome D1 heme domain Nup160 PF11715.8 KLO12885.1 - 0.082 11.5 0.0 0.15 10.6 0.0 1.3 1 1 0 1 1 1 0 Nucleoporin Nup120/160 F-box PF00646.33 KLO12886.1 - 2.6e-05 24.0 3.0 6.5e-05 22.7 3.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO12886.1 - 3.2e-05 23.7 2.4 9.2e-05 22.3 2.4 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KLO12886.1 - 0.048 13.5 0.9 0.094 12.6 0.9 1.4 1 0 0 1 1 1 0 F-box Adeno_hexon_C PF03678.14 KLO12886.1 - 0.064 12.7 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Hexon, adenovirus major coat protein, C-terminal domain Pkinase PF00069.25 KLO12887.1 - 4.4e-63 213.1 0.0 5.6e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12887.1 - 6.1e-27 94.5 0.0 8e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO12887.1 - 2.8e-05 23.6 0.0 4.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO12887.1 - 0.016 15.1 0.1 0.037 13.9 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KLO12887.1 - 0.03 13.7 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KLO12887.1 - 0.067 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain SIS PF01380.22 KLO12888.1 - 4.7e-64 214.1 0.2 1.4e-33 115.6 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KLO12888.1 - 2.4e-16 60.1 0.0 4.8e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KLO12888.1 - 4.8e-12 45.9 0.0 9.7e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KLO12888.1 - 2.5e-06 26.6 0.0 4.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II WD40 PF00400.32 KLO12889.1 - 2.9e-33 113.4 29.0 3e-06 27.9 0.6 11.1 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO12889.1 - 1.5e-20 73.3 1.0 3.7e-08 33.6 0.0 6.1 4 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO12889.1 - 3e-13 50.1 0.8 4.4e-05 23.5 0.0 5.1 3 2 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KLO12889.1 - 1.1e-07 31.1 2.5 0.028 13.4 0.0 5.3 4 1 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 KLO12889.1 - 5.3e-07 29.0 0.6 0.23 10.5 0.0 3.1 2 1 1 3 3 3 3 Coatomer WD associated region PQQ_2 PF13360.6 KLO12889.1 - 7.9e-07 28.9 6.7 8e-06 25.6 1.3 2.5 1 1 0 2 2 2 1 PQQ-like domain WD40_like PF17005.5 KLO12889.1 - 6e-06 25.8 0.2 0.38 10.0 0.0 3.8 3 1 1 4 4 4 3 WD40-like domain Nbas_N PF15492.6 KLO12889.1 - 0.00054 19.4 0.4 3.5 6.9 0.0 3.8 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KLO12889.1 - 0.0009 19.1 0.8 8 6.5 0.1 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Lactonase PF10282.9 KLO12889.1 - 0.0045 16.3 0.0 0.011 15.0 0.0 1.7 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller IKI3 PF04762.12 KLO12889.1 - 0.0057 14.7 0.2 1.5 6.7 0.0 2.3 2 0 0 2 2 2 2 IKI3 family RAB3GAP2_N PF14655.6 KLO12889.1 - 0.012 14.9 0.1 0.44 9.7 0.0 3.1 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIIC_delta PF12657.7 KLO12889.1 - 0.024 14.6 1.1 0.78 9.6 0.0 3.3 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term PQQ_3 PF13570.6 KLO12889.1 - 0.11 13.0 0.1 0.11 13.0 0.1 5.6 6 0 0 6 6 6 0 PQQ-like domain Utp8 PF10395.9 KLO12889.1 - 0.14 10.7 0.0 0.64 8.4 0.0 1.8 2 0 0 2 2 2 0 Utp8 family PQQ PF01011.21 KLO12889.1 - 0.27 11.2 1.6 13 6.0 0.3 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat Abhydrolase_6 PF12697.7 KLO12890.1 - 3.5e-14 53.9 0.0 4.6e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO12890.1 - 6e-14 52.3 0.3 2e-13 50.6 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO12890.1 - 1.6e-06 27.6 0.2 3.5e-06 26.5 0.1 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF2101 PF09874.9 KLO12894.1 - 5.4 6.7 13.3 0.52 10.0 2.3 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2101) RRM_1 PF00076.22 KLO12901.1 - 1.1e-27 95.6 0.0 1.3e-17 63.4 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 KLO12903.1 - 1.1e-12 48.9 1.9 1.6e-12 48.3 1.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GAPT PF11770.8 KLO12904.1 - 0.073 12.9 0.0 0.088 12.7 0.0 1.1 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Histone PF00125.24 KLO12905.1 - 8.9e-23 81.1 1.6 1.2e-22 80.7 1.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KLO12905.1 - 2.4e-06 27.7 0.1 5.3e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KLO12905.1 - 0.00031 21.2 0.0 0.00052 20.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KLO12905.1 - 0.012 15.6 0.2 0.015 15.3 0.2 1.1 1 0 0 1 1 1 0 YscO-like protein Bt_P21 PF05560.11 KLO12905.1 - 0.083 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Inhibitor_I34 PF10466.9 KLO12905.1 - 0.47 11.1 4.7 0.53 10.9 3.1 1.9 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 Histone_H2A_C PF16211.5 KLO12906.1 - 3.5e-17 61.8 1.1 6.8e-17 60.9 1.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KLO12906.1 - 6.5e-17 62.1 0.0 8.6e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KLO12906.1 - 3.3e-06 27.3 0.0 4.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RicinB_lectin_2 PF14200.6 KLO12908.1 - 6.3e-07 30.0 0.2 3.5e-05 24.4 0.0 2.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like zf-C3HC4_2 PF13923.6 KLO12909.1 - 3.1e-10 39.7 10.9 4.5e-10 39.2 10.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO12909.1 - 5e-10 39.1 8.5 7.8e-10 38.5 8.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO12909.1 - 1.6e-08 34.8 10.1 2.3e-08 34.2 10.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KLO12909.1 - 5.3e-07 29.4 10.4 7.8e-07 28.9 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO12909.1 - 5.2e-06 26.2 9.2 1.8e-05 24.5 9.5 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KLO12909.1 - 1.9e-05 24.5 12.8 5.9e-05 22.9 12.8 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KLO12909.1 - 2.4e-05 24.3 4.0 2.4e-05 24.3 4.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KLO12909.1 - 3.4e-05 23.9 6.2 0.0001 22.4 6.3 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KLO12909.1 - 4.4e-05 23.7 6.3 8.3e-05 22.8 6.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KLO12909.1 - 0.00075 19.2 6.7 0.0019 18.0 6.7 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KLO12909.1 - 0.0024 17.7 2.9 0.004 17.0 2.9 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.6 KLO12909.1 - 0.031 14.3 1.8 0.031 14.3 1.8 1.9 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-ANAPC11 PF12861.7 KLO12909.1 - 0.11 12.5 3.4 0.17 12.0 3.4 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.12 KLO12909.1 - 0.33 11.0 5.7 0.52 10.3 5.7 1.3 1 0 0 1 1 1 0 zinc-ribbons Prok-RING_2 PF14445.6 KLO12909.1 - 0.43 10.8 5.1 1.4 9.2 5.0 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 zf-RING_10 PF16685.5 KLO12909.1 - 1.6 8.9 8.2 3.5 7.8 8.2 1.6 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KLO12909.1 - 4.3 7.2 8.7 2.8 7.8 3.4 2.4 2 0 0 2 2 2 0 RING-like zinc finger PBP1_TM PF14812.6 KLO12909.1 - 6.9 7.1 8.7 0.4 11.1 3.3 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NUDIX PF00293.28 KLO12910.1 - 9.7e-13 48.3 0.6 1.3e-12 47.9 0.2 1.4 1 1 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 KLO12911.1 - 5.5e-67 225.9 0.0 7.2e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO12911.1 - 3.3e-30 105.2 0.0 5e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KLO12911.1 - 0.00023 20.2 0.0 0.00035 19.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KLO12911.1 - 0.21 10.9 0.0 0.54 9.5 0.0 1.5 1 1 0 1 1 1 0 Kinase-like p450 PF00067.22 KLO12912.1 - 4e-133 444.5 0.0 8.8e-67 225.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 CdiI_2 PF18593.1 KLO12912.1 - 0.0024 18.5 0.0 1.1 9.9 0.0 2.6 2 0 0 2 2 2 2 CdiI immunity protein Tam41_Mmp37 PF09139.11 KLO12912.1 - 0.17 11.3 0.0 5 6.5 0.0 2.1 2 0 0 2 2 2 0 Phosphatidate cytidylyltransferase, mitochondrial CysG_dimeriser PF10414.9 KLO12912.1 - 0.26 11.0 5.0 8.3 6.2 0.2 3.2 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region Glyco_hydro_12 PF01670.16 KLO12913.1 - 8.4e-41 140.3 13.1 9.8e-41 140.1 13.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Methyltransf_31 PF13847.6 KLO12914.1 - 6.3e-12 45.5 0.0 2.4e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KLO12914.1 - 1e-11 45.0 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO12914.1 - 2e-09 38.0 0.0 5.2e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO12914.1 - 1.2e-08 35.6 0.0 9.7e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO12914.1 - 3.9e-08 33.8 0.0 9.7e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KLO12914.1 - 0.0002 20.8 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 KLO12914.1 - 0.00042 19.7 0.0 0.00072 18.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain GidB PF02527.15 KLO12914.1 - 0.016 14.5 0.0 0.087 12.1 0.0 1.9 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G CheR PF01739.18 KLO12914.1 - 0.053 13.0 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain PrmA PF06325.13 KLO12914.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KLO12914.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 KLO12914.1 - 0.14 11.9 0.0 0.42 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KLO12914.1 - 0.22 11.1 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KLO12915.1 - 4.9e-17 62.3 0.0 7.6e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO12915.1 - 1.5e-15 57.3 0.0 6.2e-15 55.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO12915.1 - 1e-12 48.6 0.0 2.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO12915.1 - 9.1e-10 39.2 0.0 2.7e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO12915.1 - 2.8e-09 37.5 0.0 5.9e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KLO12915.1 - 5.8e-07 29.2 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_PK PF05891.12 KLO12915.1 - 4.5e-06 26.3 0.0 7.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase GidB PF02527.15 KLO12915.1 - 5.1e-06 25.9 0.0 8.9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.17 KLO12915.1 - 3e-05 23.6 0.0 0.00046 19.7 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KLO12915.1 - 0.0022 17.6 0.0 0.0046 16.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KLO12915.1 - 0.0041 16.9 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 KLO12915.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_15 PF09445.10 KLO12915.1 - 0.045 13.3 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.11 KLO12915.1 - 0.05 12.5 0.0 0.11 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.19 KLO12915.1 - 0.057 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KLO12915.1 - 0.077 12.3 0.0 0.28 10.5 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DOT1 PF08123.13 KLO12915.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_8 PF05148.15 KLO12915.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 KLO12915.1 - 0.16 11.2 0.0 0.34 10.2 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain DUF938 PF06080.12 KLO12915.1 - 0.22 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Peptidase_M19 PF01244.21 KLO12916.1 - 4.7e-106 354.6 0.0 2.6e-105 352.1 0.0 1.8 1 1 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) p450 PF00067.22 KLO12917.1 - 9.9e-63 212.5 0.0 6.4e-62 209.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 DEAD PF00270.29 KLO12918.1 - 6.8e-20 71.5 0.1 3e-19 69.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO12918.1 - 5.2e-19 68.6 0.0 2.4e-18 66.5 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.10 KLO12918.1 - 9.6e-17 60.8 0.0 9.2e-16 57.6 0.0 2.3 2 0 0 2 2 2 1 RQC domain RecQ_Zn_bind PF16124.5 KLO12918.1 - 5.2e-09 36.7 6.8 1.5e-08 35.2 6.8 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KLO12918.1 - 6e-06 26.4 0.0 2.3e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FAD_binding_2 PF00890.24 KLO12919.1 - 4.9e-86 289.4 1.5 6.1e-86 289.1 1.5 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KLO12919.1 - 2.6e-22 78.7 0.0 6.1e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KLO12919.1 - 1.4e-13 51.2 0.3 2.4e-13 50.4 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO12919.1 - 8.6e-11 41.6 0.1 1.1e-08 34.7 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO12919.1 - 8.7e-11 41.9 0.2 1.1e-09 38.4 0.1 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KLO12919.1 - 2.6e-09 36.9 0.2 3.6e-09 36.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KLO12919.1 - 4.9e-07 28.8 2.5 9e-05 21.3 0.3 3.1 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 KLO12919.1 - 1e-06 28.3 0.2 1.7e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KLO12919.1 - 1.5e-06 27.6 0.9 8.4e-05 21.8 0.4 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KLO12919.1 - 7.9e-05 22.1 0.9 0.00025 20.4 0.4 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KLO12919.1 - 8.2e-05 22.1 0.8 0.0033 16.8 0.3 3.0 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KLO12919.1 - 9.1e-05 21.8 1.2 0.023 13.9 0.4 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 KLO12919.1 - 0.00095 18.5 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KLO12919.1 - 0.0019 18.2 0.5 1 9.3 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KLO12919.1 - 0.0026 16.9 0.2 0.015 14.4 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 KLO12919.1 - 0.0037 17.8 0.4 0.042 14.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KLO12919.1 - 0.034 14.6 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KLO12920.1 - 1.3e-20 74.0 0.1 4.1e-20 72.3 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO12920.1 - 1.5e-06 27.7 0.2 0.00067 19.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO12920.1 - 7.5e-06 25.7 0.6 1.9e-05 24.4 0.2 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO12920.1 - 0.00013 22.1 0.3 0.00028 21.0 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KLO12920.1 - 0.0025 17.8 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KLO12920.1 - 0.0078 16.8 0.4 0.18 12.4 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KLO12920.1 - 0.0091 14.9 0.5 0.025 13.4 0.2 1.8 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 KLO12920.1 - 0.07 12.2 1.2 0.14 11.2 1.2 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KLO12920.1 - 0.35 9.9 1.5 0.54 9.3 1.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KLO12920.1 - 0.5 9.4 2.8 0.18 10.8 0.3 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 KLO12921.1 - 1.3e-29 103.9 0.1 1.8e-29 103.5 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KLO12921.1 - 0.0016 18.9 0.0 0.0028 18.1 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KLO12921.1 - 0.0019 17.3 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO12921.1 - 0.015 14.6 0.0 0.04 13.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KLO12921.1 - 0.021 14.1 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KLO12921.1 - 0.06 13.9 0.9 0.14 12.7 0.9 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KLO12921.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.18 KLO12922.1 - 9.8e-07 28.8 12.4 1.6e-06 28.1 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BUD22 PF09073.10 KLO12922.1 - 0.018 14.4 1.9 0.024 14.0 1.9 1.2 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 KLO12922.1 - 0.72 8.4 6.6 1.1 7.8 6.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-B_dimeris PF09026.10 KLO12922.1 - 1.7 9.1 8.0 0.16 12.4 2.8 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KLO12922.1 - 9.4 4.2 6.7 13 3.7 6.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF1582 PF07621.11 KLO12923.1 - 0.00048 20.0 1.2 0.0011 18.8 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1582) Robl_LC7 PF03259.17 KLO12924.1 - 1e-06 28.4 0.0 2e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Roadblock/LC7 domain DUF1816 PF08846.10 KLO12924.1 - 0.21 11.6 0.0 0.32 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) zf-MYND PF01753.18 KLO12925.1 - 1.1e-05 25.4 12.8 3.9e-05 23.6 12.8 2.0 1 0 0 1 1 1 1 MYND finger FAD_binding_3 PF01494.19 KLO12927.1 - 1.3e-20 73.9 0.0 2.2e-20 73.2 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO12927.1 - 4.9e-05 22.7 0.1 0.023 13.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO12927.1 - 6.9e-05 22.6 0.2 0.00029 20.5 0.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KLO12927.1 - 0.00037 21.0 0.2 0.047 14.3 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KLO12927.1 - 0.00072 19.6 0.0 0.0031 17.5 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KLO12927.1 - 0.0023 18.1 0.2 0.0053 17.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KLO12927.1 - 0.0032 16.2 2.0 0.042 12.6 0.8 2.2 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 KLO12927.1 - 0.0044 15.9 0.2 0.011 14.6 0.1 1.7 2 0 0 2 2 2 1 Tryptophan halogenase MCRA PF06100.11 KLO12927.1 - 0.059 12.1 0.2 0.13 11.1 0.1 1.6 2 0 0 2 2 2 0 MCRA family MFS_1 PF07690.16 KLO12928.1 - 4e-27 95.1 23.7 4e-27 95.1 23.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO12928.1 - 5.4e-12 45.3 0.5 5.4e-12 45.3 0.5 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KLO12928.1 - 0.00097 18.1 0.0 0.013 14.3 0.9 2.1 2 1 0 2 2 2 1 MFS_1 like family TRI12 PF06609.13 KLO12928.1 - 0.0044 15.5 0.9 0.0076 14.7 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PS_Dcarbxylase PF02666.15 KLO12929.1 - 2.6e-53 180.6 0.0 4.5e-53 179.8 0.0 1.4 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase adh_short PF00106.25 KLO12930.1 - 7.8e-25 87.5 0.0 1.1e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO12930.1 - 4.8e-15 55.8 0.0 5.7e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO12930.1 - 1.4e-05 25.1 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Dynamin_M PF01031.20 KLO12931.1 - 3.3e-33 115.1 0.0 1e-32 113.5 0.0 1.7 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KLO12931.1 - 1.2e-26 93.7 0.0 3.8e-26 92.1 0.0 1.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KLO12931.1 - 1.7e-05 24.9 0.2 0.00013 22.0 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KLO12931.1 - 5.2e-05 23.3 0.0 0.0053 16.9 0.0 2.9 3 0 0 3 3 3 1 Dynamin GTPase effector domain ArAE_1_C PF11728.8 KLO12931.1 - 0.014 15.4 1.0 0.16 11.9 0.1 2.9 3 0 0 3 3 3 0 Putative aromatic acid exporter C-terminal domain AAA_16 PF13191.6 KLO12931.1 - 0.015 15.7 0.1 0.062 13.7 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_28 PF13521.6 KLO12931.1 - 0.042 14.1 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KLO12931.1 - 0.052 13.3 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KLO12931.1 - 0.12 12.9 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter COX4 PF02936.14 KLO12933.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV zf-CHY PF05495.12 KLO12934.1 - 9.8e-14 51.6 15.0 1.9e-13 50.7 15.0 1.5 1 1 0 1 1 1 1 CHY zinc finger Cys_rich_KTR PF14205.6 KLO12934.1 - 0.002 17.9 3.9 0.71 9.7 0.1 2.5 1 1 1 2 2 2 2 Cysteine-rich KTR zf-FPG_IleRS PF06827.14 KLO12934.1 - 0.0057 16.5 0.8 0.019 14.8 0.4 2.1 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS DUF3797 PF12677.7 KLO12934.1 - 0.027 14.4 0.1 0.027 14.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) Zn_Tnp_IS1595 PF12760.7 KLO12934.1 - 0.21 11.6 10.1 15 5.7 0.0 2.9 2 1 1 3 3 3 0 Transposase zinc-ribbon domain HypA PF01155.19 KLO12934.1 - 0.68 10.0 10.7 2.6 8.1 9.0 2.4 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RNA_POL_M_15KD PF02150.16 KLO12934.1 - 0.75 9.7 0.1 0.75 9.7 0.1 3.1 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Evr1_Alr PF04777.13 KLO12934.1 - 0.9 10.1 9.6 5.4 7.5 9.6 2.3 1 1 0 1 1 1 0 Erv1 / Alr family zinc_ribbon_4 PF13717.6 KLO12934.1 - 1 9.3 11.1 3.5 7.6 0.1 3.7 3 1 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KLO12934.1 - 1.9 8.3 9.1 2.2 8.1 0.7 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-DNL PF05180.12 KLO12934.1 - 2.8 7.9 10.1 0.55 10.2 2.7 2.7 2 1 0 2 2 2 0 DNL zinc finger Zn-ribbon_8 PF09723.10 KLO12934.1 - 4.9 7.4 15.4 0.19 11.9 4.3 2.6 1 1 2 3 3 3 0 Zinc ribbon domain Baculo_PEP_C PF04513.12 KLO12935.1 - 2.1e-05 24.6 9.9 0.01 15.9 1.9 2.5 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1700 PF08006.11 KLO12935.1 - 0.026 14.1 5.4 0.041 13.4 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DALR_2 PF09190.11 KLO12935.1 - 0.09 13.3 2.2 0.28 11.7 2.2 1.9 1 0 0 1 1 1 0 DALR domain RIFIN PF02009.16 KLO12935.1 - 0.91 9.4 4.2 1.1 9.1 4.2 1.1 1 0 0 1 1 1 0 Rifin SurA_N PF09312.11 KLO12936.1 - 0.005 16.9 1.6 0.007 16.4 1.6 1.1 1 0 0 1 1 1 1 SurA N-terminal domain HsbA PF12296.8 KLO12936.1 - 0.19 12.2 7.0 0.27 11.7 7.0 1.2 1 0 0 1 1 1 0 Hydrophobic surface binding protein A DUF3759 PF12585.8 KLO12937.1 - 9.5e-08 32.0 0.8 1.6e-07 31.3 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) HSP20 PF00011.21 KLO12938.1 - 0.026 14.7 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Hsp20/alpha crystallin family HMG-CoA_red PF00368.18 KLO12939.1 - 1e-142 475.5 3.9 1.4e-142 475.0 3.9 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 KLO12939.1 - 1.8e-09 37.6 3.2 0.00028 20.7 0.2 2.8 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation HPIH PF13323.6 KLO12939.1 - 0.049 13.5 0.7 0.14 12.0 0.7 1.7 1 0 0 1 1 1 0 N-terminal domain with HPIH motif zf-MYND PF01753.18 KLO12940.1 - 1.9e-06 27.9 11.8 1.9e-06 27.9 11.8 1.7 2 0 0 2 2 2 1 MYND finger KH_1 PF00013.29 KLO12941.1 - 4.2e-09 36.1 0.2 2.5e-06 27.2 0.1 2.6 2 1 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.6 KLO12942.1 - 1.9e-09 37.3 2.7 1.9e-09 37.3 2.7 4.0 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO12942.1 - 5.1e-09 36.3 3.3 5.1e-09 36.3 3.3 4.3 5 0 0 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 KLO12942.1 - 1.7e-08 34.2 3.7 1.7e-08 34.2 3.7 4.0 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO12942.1 - 1.1e-05 25.3 1.3 1.1e-05 25.3 1.3 2.6 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KLO12942.1 - 3.6e-05 23.5 2.7 3.6e-05 23.5 2.7 3.6 5 1 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KLO12942.1 - 5.1e-05 23.5 2.9 5.1e-05 23.5 2.9 3.5 4 2 0 4 4 3 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KLO12942.1 - 0.00011 22.0 2.2 0.00011 22.0 2.2 3.8 4 0 0 4 4 3 1 Prokaryotic RING finger family 4 zf-C2H2_4 PF13894.6 KLO12942.1 - 0.00041 21.0 35.0 0.18 12.7 0.1 6.4 6 0 0 6 6 6 2 C2H2-type zinc finger zf-RING_5 PF14634.6 KLO12942.1 - 0.00043 20.2 5.0 0.00043 20.2 5.0 4.3 5 1 1 6 6 6 1 zinc-RING finger domain Redoxin PF08534.10 KLO12942.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Redoxin zf-C2H2_11 PF16622.5 KLO12942.1 - 0.015 15.0 0.2 0.084 12.6 0.2 4.9 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KLO12942.1 - 0.16 12.7 2.4 1.7 9.3 0.1 3.0 2 2 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 KLO12942.1 - 0.2 12.2 0.1 0.2 12.2 0.1 5.7 6 0 0 6 6 6 0 Zinc finger, C2H2 type FYVE PF01363.21 KLO12942.1 - 0.45 10.7 16.7 4.5 7.5 4.9 5.2 4 1 0 4 4 4 0 FYVE zinc finger zf-RING_4 PF14570.6 KLO12942.1 - 0.53 10.1 11.9 0.098 12.5 3.2 3.5 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-met PF12874.7 KLO12942.1 - 1.4 9.4 32.7 0.23 11.9 1.3 5.4 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C3H2C3 PF17122.5 KLO12942.1 - 5.3 7.2 9.5 12 6.0 3.5 3.4 2 1 1 3 3 3 0 Zinc-finger zf-C2H2_2 PF12756.7 KLO12942.1 - 8.4 6.8 20.9 1.2 9.6 1.1 4.4 4 2 1 5 5 5 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 KLO12942.1 - 8.6 7.1 7.2 7.5 7.3 0.5 3.2 3 0 0 3 3 3 0 FOXP coiled-coil domain DUF4097 PF13349.6 KLO12944.1 - 0.0012 18.2 1.8 0.002 17.5 1.8 1.3 1 0 0 1 1 1 1 Putative adhesin NGP1NT PF08153.12 KLO12944.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 NGP1NT (NUC091) domain F-box-like PF12937.7 KLO12945.1 - 7.5e-06 25.7 0.1 1.9e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO12945.1 - 6.2e-05 22.8 1.2 0.28 11.1 0.1 2.9 2 0 0 2 2 2 2 F-box domain Ribosomal_L44 PF00935.19 KLO12946.1 - 9e-38 128.6 11.0 1.5e-37 127.9 11.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 Nodulin_late PF07127.11 KLO12946.1 - 0.022 15.1 0.3 0.043 14.1 0.3 1.5 1 0 0 1 1 1 0 Late nodulin protein Cathelicidins PF00666.17 KLO12946.1 - 0.082 13.2 0.6 0.082 13.2 0.6 1.7 2 0 0 2 2 2 0 Cathelicidin zf-RING_2 PF13639.6 KLO12947.1 - 2.8e-08 34.0 2.9 2.8e-08 34.0 2.9 3.2 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KLO12947.1 - 3.8e-06 26.6 5.4 3.8e-06 26.6 5.4 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KLO12947.1 - 9.3e-06 25.8 7.0 2.4e-05 24.5 4.4 3.1 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KLO12947.1 - 1e-05 25.3 2.3 1e-05 25.3 2.3 3.8 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO12947.1 - 0.00021 21.3 2.2 0.00021 21.3 2.2 2.5 3 0 0 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KLO12947.1 - 0.00022 21.1 2.6 0.00022 21.1 2.6 4.5 5 1 1 6 6 5 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KLO12947.1 - 0.0009 19.1 3.4 0.0009 19.1 3.4 3.7 5 1 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO12947.1 - 0.002 18.0 1.1 0.002 18.0 1.1 3.4 3 1 1 4 4 3 1 Prokaryotic RING finger family 4 zf_C2H2_ZHX PF18387.1 KLO12947.1 - 0.0061 16.2 11.7 0.12 12.0 0.1 4.9 4 1 0 4 4 4 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C3HC4_4 PF15227.6 KLO12947.1 - 0.018 15.2 0.7 0.018 15.2 0.7 4.5 5 0 0 5 5 5 0 zinc finger of C3HC4-type, RING zf-C2H2_4 PF13894.6 KLO12947.1 - 0.022 15.6 19.1 0.71 10.9 0.1 6.0 6 0 0 6 6 5 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KLO12947.1 - 0.048 13.7 0.1 0.048 13.7 0.1 5.1 6 0 0 6 6 6 0 C2H2-type zinc finger Rtf2 PF04641.12 KLO12947.1 - 0.13 11.6 1.5 0.39 10.0 0.4 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger zf-Nse PF11789.8 KLO12947.1 - 0.26 11.2 3.7 0.23 11.3 1.2 2.3 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2_3rep PF18868.1 KLO12947.1 - 1 10.1 6.5 8.2 7.1 0.4 3.1 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Glyco_hydro_16 PF00722.21 KLO12948.1 - 3.3e-06 26.7 0.1 5.9e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-MYND PF01753.18 KLO12950.1 - 1.8e-08 34.3 20.8 1.8e-08 34.3 20.8 2.3 2 0 0 2 2 2 1 MYND finger DUF2121 PF09894.9 KLO12950.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) zf-Mss51 PF13824.6 KLO12950.1 - 5.9 7.1 13.3 2.6 8.2 8.3 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 MutS_V PF00488.21 KLO12951.1 - 2.6e-84 282.0 0.2 4.5e-84 281.2 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KLO12951.1 - 2.4e-34 119.2 1.0 6.4e-34 117.8 1.0 1.8 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KLO12951.1 - 5.4e-18 65.1 0.5 1.5e-17 63.7 0.5 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KLO12951.1 - 1.9e-16 60.6 0.5 1.9e-16 60.6 0.5 2.5 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 KLO12951.1 - 2e-12 47.4 0.0 5.6e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain I AAA_23 PF13476.6 KLO12951.1 - 1.2 9.7 0.0 1.2 9.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain Lipase_3 PF01764.25 KLO12952.1 - 3.2e-18 66.0 0.0 5.8e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Lipase_3 PF01764.25 KLO12953.1 - 2.7e-19 69.5 0.0 4.9e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Asp PF00026.23 KLO12954.1 - 4.9e-29 101.8 8.9 1.2e-27 97.2 8.9 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 KLO12954.1 - 0.00017 22.1 1.7 0.023 15.3 0.4 3.0 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KLO12954.1 - 0.00026 21.6 3.1 0.0022 18.6 2.2 2.5 2 0 0 2 2 2 1 Aspartyl protease Kelch_3 PF13415.6 KLO12955.1 - 0.044 14.1 1.3 2.3 8.6 0.0 3.6 3 0 0 3 3 3 0 Galactose oxidase, central domain Arylsulfotrans PF05935.11 KLO12955.1 - 0.072 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) DUF1180 PF06679.12 KLO12955.1 - 1.2 9.5 4.2 2.2 8.7 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) WAPL PF07814.13 KLO12956.1 - 4.9e-13 48.6 0.3 1.2e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin HAD_2 PF13419.6 KLO12957.1 - 5e-08 33.2 0.0 1e-07 32.2 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO12957.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like UBA_4 PF14555.6 KLO12957.1 - 0.16 11.8 0.1 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain KDZ PF18758.1 KLO12958.1 - 1.8e-46 158.6 0.5 2.9e-46 157.9 0.5 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO12958.1 - 1.3e-28 99.3 0.0 4.1e-28 97.7 0.0 1.9 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO12958.1 - 2e-06 27.9 0.0 8.8e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KLO12958.1 - 0.023 14.5 0.2 0.089 12.7 0.0 2.1 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases DUF2797 PF10977.8 KLO12958.1 - 0.12 12.3 1.2 0.35 10.7 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) MutS_III PF05192.18 KLO12959.1 - 0.096 12.9 0.3 0.54 10.5 0.3 2.1 1 1 0 1 1 1 0 MutS domain III Apolipoprotein PF01442.18 KLO12959.1 - 0.98 9.3 6.9 0.31 10.9 1.5 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Zn_clus PF00172.18 KLO12962.1 - 6.1e-10 39.1 8.3 1e-09 38.4 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DivIC PF04977.15 KLO12962.1 - 0.52 10.1 2.2 0.97 9.2 2.2 1.4 1 0 0 1 1 1 0 Septum formation initiator F-box-like PF12937.7 KLO12963.1 - 0.0045 16.8 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO12963.1 - 0.049 14.1 2.3 18 5.9 0.0 4.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Pup_ligase PF03136.15 KLO12963.1 - 0.09 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Pup-ligase protein Folliculin_C PF16692.5 KLO12964.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Folliculin C-terminal domain F-box-like PF12937.7 KLO12967.1 - 0.017 15.0 0.0 0.062 13.2 0.0 2.1 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KLO12970.1 - 0.0038 17.1 0.9 0.17 11.8 0.4 3.5 3 1 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KLO12970.1 - 0.0067 16.8 1.1 24 5.5 0.0 4.5 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) DSPc PF00782.20 KLO12976.1 - 3.3e-30 104.6 0.0 4.1e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KLO12976.1 - 4.1e-05 23.3 0.0 5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KLO12976.1 - 0.0072 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 KLO12976.1 - 0.019 15.3 0.6 0.38 11.1 0.6 2.3 1 1 0 1 1 1 0 Rit1 DUSP-like domain FeoB_C PF07664.12 KLO12977.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus F-box-like PF12937.7 KLO12979.1 - 0.0013 18.6 2.1 0.0043 16.9 2.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO12979.1 - 0.11 13.0 1.1 29 5.3 0.0 4.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO12980.1 - 2.7e-05 24.0 1.7 4.3e-05 23.3 0.5 2.1 2 0 0 2 2 2 1 F-box-like GPW_gp25 PF04965.14 KLO12980.1 - 0.13 12.0 0.2 0.3 10.9 0.2 1.7 1 0 0 1 1 1 0 Gene 25-like lysozyme TetR_C_35 PF18556.1 KLO12981.1 - 0.026 14.6 0.1 0.048 13.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain YtxC PF08812.11 KLO12981.1 - 0.21 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 YtxC-like family Transferase PF02458.15 KLO12983.1 - 8.4e-07 28.0 0.0 1.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Transferase family Peptidase_M15_2 PF05951.13 KLO12983.1 - 0.0082 15.8 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF882) Condensation PF00668.20 KLO12983.1 - 0.033 12.9 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 Condensation domain M-factor PF03855.13 KLO12984.1 - 0.052 13.7 1.0 0.14 12.3 1.0 1.7 1 0 0 1 1 1 0 M-factor RIO1 PF01163.22 KLO12986.1 - 3.7e-72 241.9 0.0 3.7e-72 241.9 0.0 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KLO12986.1 - 2.2e-05 24.5 0.9 0.096 12.6 0.2 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KLO12986.1 - 0.0013 18.1 1.0 0.017 14.5 1.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KLO12986.1 - 0.0036 16.7 0.0 0.0078 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KLO12986.1 - 0.015 14.1 0.6 0.015 14.1 0.6 2.4 3 0 0 3 3 3 0 Fungal protein kinase CDC45 PF02724.14 KLO12986.1 - 1 7.6 25.2 0.15 10.3 11.2 2.1 2 0 0 2 2 2 0 CDC45-like protein YL1 PF05764.13 KLO12986.1 - 8.8 6.4 36.0 2.8 8.0 8.9 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Sigma70_ner PF04546.13 KLO12986.1 - 9.3 6.1 19.1 2.1 8.2 4.5 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region UPF0542 PF15086.6 KLO12987.1 - 0.22 11.5 2.6 1.5 8.8 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 SpoIIM PF01944.17 KLO12987.1 - 0.39 10.7 8.2 2.1 8.4 1.3 2.3 2 1 0 2 2 2 0 Stage II sporulation protein M ILVD_EDD PF00920.21 KLO12991.1 - 1.8e-209 696.7 0.3 2.2e-209 696.4 0.0 1.3 2 0 0 2 2 2 1 Dehydratase family Methyltransf_25 PF13649.6 KLO12992.1 - 1.7e-12 47.9 0.0 3.6e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO12992.1 - 1.7e-11 44.6 0.0 2.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO12992.1 - 6.2e-11 42.4 0.0 8.2e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO12992.1 - 3.3e-09 36.7 0.0 1.2e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO12992.1 - 2.6e-07 31.3 0.0 5.3e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO12992.1 - 9.4e-07 28.4 0.0 3.1e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KLO12992.1 - 8.2e-05 22.6 0.0 0.00015 21.7 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase TPMT PF05724.11 KLO12992.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) p450 PF00067.22 KLO12993.1 - 1.4e-65 221.9 0.0 1.7e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 KLO12994.1 - 1e-24 87.2 8.0 1.4e-24 86.8 8.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family TctB PF07331.11 KLO12994.1 - 4.1 7.7 10.5 2.6 8.3 4.2 2.5 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Methyltransf_2 PF00891.18 KLO12995.1 - 1.3e-23 83.4 0.0 1.4e-22 80.0 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KLO12995.1 - 0.0024 17.5 0.0 0.0095 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KLO12995.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_12 PF08242.12 KLO12995.1 - 0.012 16.4 0.0 0.029 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DprA_WH PF17782.1 KLO12995.1 - 0.018 15.1 0.4 0.047 13.8 0.4 1.6 1 0 0 1 1 1 0 DprA winged helix domain MarR_2 PF12802.7 KLO12995.1 - 0.022 14.7 0.0 0.057 13.3 0.0 1.7 1 0 0 1 1 1 0 MarR family Dimerisation2 PF16864.5 KLO12995.1 - 0.047 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_25 PF13649.6 KLO12995.1 - 0.085 13.6 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RPA_C PF08784.11 KLO12995.1 - 0.11 13.1 0.0 0.33 11.6 0.0 1.8 1 1 0 1 1 1 0 Replication protein A C terminal p450 PF00067.22 KLO12996.1 - 1.1e-60 205.7 0.0 1.8e-60 205.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MotB_plug PF13677.6 KLO12998.1 - 0.16 11.6 0.1 0.38 10.4 0.1 1.6 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB MRAP PF15183.6 KLO12998.1 - 0.26 11.2 3.3 5.1 7.1 0.1 2.5 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family AMP-binding PF00501.28 KLO12999.1 - 1.1e-27 96.7 0.0 6.4e-26 90.9 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 KLO12999.1 - 3e-08 33.9 0.0 1.5e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Nas2_N PF18265.1 KLO13000.1 - 1.7e-26 91.9 0.1 2.4e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KLO13000.1 - 5.9e-06 26.0 0.1 2.9e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KLO13000.1 - 0.00011 22.5 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KLO13000.1 - 0.00018 21.8 0.0 0.00051 20.4 0.0 1.8 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 KLO13000.1 - 0.086 13.2 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 PDZ domain AidB_N PF18158.1 KLO13001.1 - 6.2e-26 91.2 0.0 1.2e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 KLO13001.1 - 1.9e-19 70.4 0.7 8.2e-19 68.3 0.4 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KLO13001.1 - 3.8e-13 49.4 0.0 1.3e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KLO13001.1 - 1.5e-07 31.8 0.0 4e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acetyltransf_18 PF18014.1 KLO13001.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Syntaxin_2 PF14523.6 KLO13003.1 - 4.4e-20 71.9 5.7 4.4e-20 71.9 5.7 3.0 2 1 1 3 3 3 1 Syntaxin-like protein SNARE PF05739.19 KLO13003.1 - 2e-11 43.7 7.3 5.4e-11 42.3 1.0 3.2 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 KLO13003.1 - 7.6e-09 35.5 11.0 5.3e-08 32.8 11.0 2.1 1 1 0 1 1 1 1 Syntaxin Prominin PF05478.11 KLO13003.1 - 0.0022 16.0 10.7 0.0044 15.1 0.8 2.0 1 1 1 2 2 2 2 Prominin Trimer_CC PF08954.11 KLO13003.1 - 0.014 14.9 0.1 0.73 9.4 0.1 3.2 2 2 0 2 2 2 0 Trimerisation motif MCPsignal PF00015.21 KLO13003.1 - 0.037 13.8 0.4 0.037 13.8 0.4 2.7 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.21 KLO13003.1 - 0.047 13.5 6.3 0.064 13.1 0.1 3.1 2 1 1 3 3 3 0 Synaptobrevin DUF4337 PF14235.6 KLO13003.1 - 0.46 10.6 4.8 6.1 6.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF16 PF01519.16 KLO13003.1 - 0.88 10.1 11.6 0.79 10.2 0.7 3.1 2 1 0 2 2 2 0 Protein of unknown function DUF16 TMPIT PF07851.13 KLO13003.1 - 1.4 8.0 6.3 9 5.4 0.1 2.2 1 1 2 3 3 3 0 TMPIT-like protein UPF0242 PF06785.11 KLO13003.1 - 3.3 7.8 14.7 89 3.1 14.6 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2203 PF09969.9 KLO13003.1 - 5.9 7.6 6.7 7.5 7.3 0.3 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) XhlA PF10779.9 KLO13003.1 - 8.7 6.6 9.1 5.8 7.2 0.4 2.7 3 0 0 3 3 3 0 Haemolysin XhlA Gag_spuma PF03276.14 KLO13006.1 - 0.12 10.7 0.3 0.17 10.3 0.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Pkinase PF00069.25 KLO13007.1 - 2.4e-71 240.2 0.0 2.9e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13007.1 - 3.5e-44 151.0 0.0 4.4e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO13007.1 - 3.7e-08 33.0 0.0 9.5e-08 31.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KLO13007.1 - 0.008 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KLO13007.1 - 0.021 14.5 0.1 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Radical_SAM_C PF16199.5 KLO13007.1 - 0.057 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Radical_SAM C-terminal domain Pkinase_fungal PF17667.1 KLO13007.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KLO13007.1 - 0.14 12.0 0.1 0.4 10.6 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nop PF01798.18 KLO13008.1 - 4.2e-86 288.2 0.0 4.2e-86 288.2 0.0 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KLO13008.1 - 5.1e-20 71.6 0.2 5.1e-20 71.6 0.2 2.6 2 1 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.12 KLO13008.1 - 1.3 9.2 15.5 2.4 8.4 15.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 KLO13008.1 - 1.8 8.3 23.6 3.6 7.3 23.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KLO13008.1 - 2.6 6.2 20.0 4.1 5.6 20.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Na_H_Exchanger PF00999.21 KLO13009.1 - 4.4e-48 164.0 46.6 6.4e-48 163.4 46.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 KLO13009.1 - 0.019 15.5 1.1 0.13 12.8 0.0 2.5 3 0 0 3 3 3 0 Universal stress protein family Trp_halogenase PF04820.14 KLO13011.1 - 1.8e-30 106.2 0.0 6.6e-16 58.2 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KLO13011.1 - 1.3e-12 47.7 0.0 1.8e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KLO13011.1 - 3.7e-06 27.1 0.1 1.3e-05 25.3 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO13011.1 - 8.2e-05 22.0 0.0 0.00016 21.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO13011.1 - 0.00012 21.0 0.0 0.00018 20.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KLO13011.1 - 0.00012 21.3 0.1 0.00022 20.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KLO13011.1 - 0.00015 21.3 0.1 0.00027 20.4 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KLO13011.1 - 0.00016 21.4 0.2 0.00031 20.4 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KLO13011.1 - 0.00029 20.0 0.1 0.00067 18.8 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KLO13011.1 - 0.014 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO13011.1 - 0.018 15.6 0.3 0.049 14.2 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO13011.1 - 0.034 13.4 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KLO13011.1 - 0.042 13.2 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KLO13011.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TFIIS_C PF01096.18 KLO13012.1 - 2.8e-21 75.1 5.9 2.8e-21 75.1 5.9 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KLO13012.1 - 1e-07 31.7 2.2 1e-07 31.7 2.2 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KLO13012.1 - 4.2e-06 26.6 10.8 0.00011 22.1 1.0 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KLO13012.1 - 0.0043 17.0 7.6 0.058 13.4 0.0 3.2 2 2 0 2 2 2 1 PhnA Zinc-Ribbon DUF3797 PF12677.7 KLO13012.1 - 0.11 12.4 10.6 0.67 9.9 4.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) zinc-ribbons_6 PF07191.12 KLO13012.1 - 0.54 10.3 11.5 0.86 9.6 1.3 2.8 2 1 0 2 2 2 0 zinc-ribbons C1_1 PF00130.22 KLO13012.1 - 0.56 10.1 10.7 0.48 10.4 3.1 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KLO13012.1 - 0.82 9.6 15.2 0.54 10.2 1.6 3.0 2 2 0 2 2 2 0 PHD-finger HypA PF01155.19 KLO13012.1 - 0.99 9.4 8.5 13 5.9 8.5 2.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3716 PF12511.8 KLO13012.1 - 1.1 9.4 12.6 2.5 8.2 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) TF_Zn_Ribbon PF08271.12 KLO13012.1 - 4 7.0 15.7 0.091 12.3 2.7 3.2 2 2 1 3 3 3 0 TFIIB zinc-binding zf-C3HC4_4 PF15227.6 KLO13012.1 - 6 7.1 11.6 21 5.4 0.1 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Cys_rich_KTR PF14205.6 KLO13012.1 - 7.5 6.4 9.9 3.6 7.5 0.4 3.0 3 1 0 3 3 3 0 Cysteine-rich KTR Zn_Tnp_IS1 PF03811.13 KLO13012.1 - 8.4 6.2 14.6 7.5 6.4 0.1 3.7 3 1 0 3 3 3 0 InsA N-terminal domain zf-RING_11 PF17123.5 KLO13013.1 - 0.023 14.4 2.5 0.027 14.2 0.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 KLO13013.1 - 0.048 14.0 0.6 0.2 12.0 0.1 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain p450 PF00067.22 KLO13021.1 - 4.2e-66 223.6 0.7 8.4e-65 219.3 0.7 2.5 1 1 0 1 1 1 1 Cytochrome P450 Cupin_1 PF00190.22 KLO13022.1 - 1.8e-41 141.2 0.2 1.3e-20 73.6 0.1 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KLO13022.1 - 3.2e-26 90.8 0.2 9.1e-12 44.5 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KLO13022.1 - 2.6e-10 39.9 0.1 0.00011 21.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KLO13022.1 - 7.7e-05 22.6 0.0 0.02 14.8 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase AraC_binding PF02311.19 KLO13022.1 - 0.00027 20.8 0.1 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain ARD PF03079.14 KLO13022.1 - 0.00066 19.9 0.0 0.0085 16.3 0.0 2.1 2 0 0 2 2 2 1 ARD/ARD' family 3-HAO PF06052.12 KLO13022.1 - 0.0034 17.0 0.0 0.41 10.3 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.12 KLO13022.1 - 0.012 15.1 0.0 0.54 9.7 0.0 2.2 2 0 0 2 2 2 0 Cupin superfamily protein GPI PF06560.11 KLO13022.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) cNMP_binding PF00027.29 KLO13022.1 - 0.041 14.0 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Dak1 PF02733.17 KLO13023.1 - 3.6e-97 325.0 0.0 5.1e-97 324.5 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KLO13023.1 - 1.1e-42 145.9 0.0 2e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 DAK2 domain zf-H2C2_2 PF13465.6 KLO13025.1 - 2.7e-07 30.7 0.6 2.7e-07 30.7 0.6 4.2 4 0 0 4 4 4 1 Zinc-finger double domain Zn_clus PF00172.18 KLO13025.1 - 0.00025 21.1 6.0 0.00047 20.2 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KLO13025.1 - 0.00057 20.2 21.6 0.00079 19.7 3.3 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO13025.1 - 0.00067 20.3 11.9 0.0027 18.4 2.7 4.2 4 0 0 4 4 3 2 C2H2-type zinc finger zf-met PF12874.7 KLO13025.1 - 0.00087 19.6 1.6 0.0017 18.7 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KLO13025.1 - 0.17 12.3 4.2 1 9.7 0.5 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KLO13025.1 - 0.33 11.3 5.0 1.4 9.2 5.3 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_SprT PF17283.2 KLO13025.1 - 0.35 10.8 4.8 0.83 9.6 4.8 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_11 PF16622.5 KLO13025.1 - 0.51 10.1 5.9 0.55 10.0 1.3 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type FYVE PF01363.21 KLO13025.1 - 0.93 9.7 11.5 0.1 12.7 6.0 2.1 2 0 0 2 2 2 0 FYVE zinc finger Zn_Tnp_IS1 PF03811.13 KLO13025.1 - 2 8.2 7.2 6.9 6.5 7.2 2.0 1 0 0 1 1 1 0 InsA N-terminal domain zf-C2H2_6 PF13912.6 KLO13025.1 - 4.7 7.3 11.2 0.71 9.9 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Uricase PF01014.18 KLO13026.1 - 8.8e-65 216.9 0.0 4.7e-32 111.0 0.0 2.1 2 0 0 2 2 2 2 Uricase Med4 PF10018.9 KLO13027.1 - 0.19 11.4 0.1 0.27 10.9 0.1 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Glyoxalase PF00903.25 KLO13028.1 - 6.5e-25 87.8 0.1 8.1e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KLO13028.1 - 6e-08 32.9 0.0 7.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KLO13028.1 - 5e-06 27.3 0.0 7.5e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KLO13028.1 - 0.00063 19.9 0.0 0.00087 19.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KLO13028.1 - 0.004 17.1 0.1 0.57 10.1 0.1 2.3 2 1 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.6 KLO13028.1 - 0.082 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal ATP-synt_G PF04718.15 KLO13029.1 - 1.3e-14 54.8 1.7 2e-14 54.2 0.1 2.0 2 1 0 2 2 2 1 Mitochondrial ATP synthase g subunit MT0933_antitox PF14013.6 KLO13029.1 - 0.033 14.5 2.0 0.068 13.5 2.0 1.5 1 0 0 1 1 1 0 MT0933-like antitoxin protein Pho88 PF10032.9 KLO13030.1 - 3.1e-73 244.9 0.0 3.5e-73 244.7 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) PH PF00169.29 KLO13031.1 - 1.4e-06 28.8 0.0 2.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 PH domain Rab5-bind PF09311.11 KLO13031.1 - 0.059 12.8 4.5 0.31 10.4 1.1 2.2 2 0 0 2 2 2 0 Rabaptin-like protein HTH_18 PF12833.7 KLO13031.1 - 0.083 13.2 0.9 0.21 11.9 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Syntaxin_2 PF14523.6 KLO13031.1 - 0.1 13.0 0.4 0.1 13.0 0.4 1.9 2 0 0 2 2 2 0 Syntaxin-like protein OmpH PF03938.14 KLO13031.1 - 0.16 12.3 2.9 0.29 11.4 0.0 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) BAR_2 PF10455.9 KLO13031.1 - 0.18 10.9 2.7 0.3 10.2 1.9 1.8 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking GIT_CC PF16559.5 KLO13031.1 - 1.2 9.1 3.7 5 7.1 0.2 2.9 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Glyco_hydro_28 PF00295.17 KLO13032.1 - 6e-20 71.5 5.0 8.6e-20 71.0 5.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF410 PF04190.13 KLO13033.1 - 3.4e-76 256.4 0.0 4.5e-76 256.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Steroid_dh PF02544.16 KLO13034.1 - 1.2e-33 116.2 5.1 1.2e-33 116.2 5.1 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 KLO13034.1 - 1.2e-06 28.1 0.1 2.1e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF1295 PF06966.12 KLO13034.1 - 0.027 14.0 0.3 0.048 13.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Ubiquitin_2 PF14560.6 KLO13034.1 - 0.035 14.6 0.1 0.1 13.1 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain UAE_UbL PF14732.6 KLO13034.1 - 0.13 12.8 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Abhydrolase_1 PF00561.20 KLO13035.1 - 2.2e-20 73.4 0.0 1.4e-18 67.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO13035.1 - 9.5e-16 59.1 0.0 1.6e-15 58.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO13035.1 - 4.9e-11 42.4 0.0 8.5e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KLO13035.1 - 7.7e-09 35.6 0.0 5.8e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 KLO13035.1 - 2.4e-08 34.4 0.0 3.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 KLO13035.1 - 0.00035 20.2 0.0 0.00055 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 KLO13035.1 - 0.00075 18.5 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Palm_thioest PF02089.15 KLO13035.1 - 0.0021 17.9 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PMM PF03332.13 KLO13035.1 - 0.018 14.8 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase Chlorophyllase PF07224.11 KLO13035.1 - 0.031 13.3 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.20 KLO13035.1 - 0.052 13.2 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Putative esterase Abhydrolase_3 PF07859.13 KLO13035.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 KLO13035.1 - 0.08 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) UvsW PF11637.8 KLO13035.1 - 0.15 12.2 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW Arv1 PF04161.13 KLO13036.1 - 1e-34 120.5 0.0 1.4e-34 120.1 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family Terpene_synth_C PF03936.16 KLO13037.1 - 4.2e-05 23.0 0.0 6.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 KLO13037.1 - 0.00065 18.7 0.0 0.00099 18.1 0.0 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.16 KLO13038.1 - 0.0036 16.7 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.16 KLO13039.1 - 0.013 14.8 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain DUF3334 PF11813.8 KLO13039.1 - 0.073 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) Terpene_synth_C PF03936.16 KLO13043.1 - 6e-06 25.8 0.0 1.1e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DUF3678 PF12435.8 KLO13043.1 - 0.094 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) BTB_3 PF16017.5 KLO13043.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain ThuA PF06283.11 KLO13044.1 - 3.3e-60 203.9 0.3 3.9e-60 203.7 0.3 1.1 1 0 0 1 1 1 1 Trehalose utilisation ArgoMid PF16487.5 KLO13044.1 - 0.051 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Mid domain of argonaute DDOST_48kD PF03345.14 KLO13044.1 - 0.052 12.4 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta zf-HIT PF04438.16 KLO13045.1 - 2.6e-06 27.2 10.0 4.2e-06 26.5 10.0 1.4 1 0 0 1 1 1 1 HIT zinc finger WD40 PF00400.32 KLO13046.1 - 8.1e-20 70.8 0.0 6.5e-05 23.6 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO13046.1 - 3.9e-08 33.5 0.0 0.37 11.1 0.0 4.3 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KLO13046.1 - 0.13 11.3 0.0 0.69 8.9 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region RNA_pol_Rpb5_C PF01191.19 KLO13047.1 - 1.7e-31 107.9 0.1 4.9e-31 106.4 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KLO13047.1 - 5.5e-30 103.8 0.0 1.4e-29 102.5 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KLO13047.1 - 0.013 15.5 0.0 0.022 14.8 0.0 1.5 1 1 0 1 1 1 0 Restriction endonuclease Herpes_IE2_3 PF03361.14 KLO13047.1 - 0.022 14.7 0.1 0.033 14.1 0.1 1.2 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Trigger_C PF05698.14 KLO13047.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus DnaJ_C PF01556.18 KLO13048.1 - 5e-41 140.2 0.2 6.4e-41 139.9 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KLO13048.1 - 1.4e-26 92.4 1.0 2.3e-26 91.7 1.0 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KLO13048.1 - 5.4e-14 52.3 17.4 9.2e-14 51.6 17.4 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KLO13048.1 - 3.7e-05 23.6 11.8 0.0071 16.3 1.7 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KLO13048.1 - 0.034 14.2 6.7 1.7 8.7 2.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KLO13048.1 - 0.62 10.1 8.8 3.2 7.9 1.4 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 KLO13048.1 - 1.6 9.1 6.8 47 4.4 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon A2L_zn_ribbon PF08792.10 KLO13048.1 - 5 7.0 15.8 9.7 6.0 2.6 4.1 3 1 0 3 3 3 0 A2L zinc ribbon domain zinc-ribbons_6 PF07191.12 KLO13048.1 - 7.6 6.6 8.5 3.7 7.6 2.7 2.4 2 0 0 2 2 2 0 zinc-ribbons Methyltr_RsmB-F PF01189.17 KLO13049.1 - 1.7e-25 89.8 0.0 3.5e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F IL2 PF00715.17 KLO13049.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Interleukin 2 SF1-HH PF16275.5 KLO13050.1 - 3.3e-38 130.5 1.0 3.3e-38 130.5 1.0 1.6 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KLO13050.1 - 1.3e-11 44.0 8.4 2.4e-05 24.2 2.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KLO13050.1 - 1.3e-07 31.5 7.6 0.00019 21.3 3.8 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KLO13050.1 - 6e-05 22.8 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.6 KLO13050.1 - 0.0006 19.6 5.7 0.11 12.3 0.4 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KLO13050.1 - 0.0071 16.1 6.9 0.44 10.3 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle CCDC-167 PF15188.6 KLO13050.1 - 0.03 14.7 0.6 6.2 7.2 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 zf-CCHC_5 PF14787.6 KLO13050.1 - 0.8 9.5 3.7 1.1 9.0 0.2 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger bZIP_2 PF07716.15 KLO13051.1 - 0.00032 20.7 3.2 0.00032 20.7 3.2 1.6 2 0 0 2 2 2 1 Basic region leucine zipper Shugoshin_N PF07558.11 KLO13051.1 - 0.00033 20.4 1.1 0.00057 19.7 1.1 1.3 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.21 KLO13051.1 - 0.00035 20.6 9.5 0.00058 19.9 9.5 1.4 1 1 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 KLO13051.1 - 0.005 17.1 0.2 0.0071 16.6 0.2 1.2 1 0 0 1 1 1 1 TSC-22/dip/bun family HAP1_N PF04849.13 KLO13051.1 - 0.015 14.5 0.8 0.016 14.5 0.8 1.0 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Nnf1 PF03980.14 KLO13051.1 - 0.016 15.6 0.9 0.02 15.3 0.9 1.1 1 0 0 1 1 1 0 Nnf1 BMFP PF04380.13 KLO13051.1 - 0.12 12.9 3.1 0.17 12.4 3.1 1.2 1 0 0 1 1 1 0 Membrane fusogenic activity M PF02370.16 KLO13051.1 - 0.18 12.5 3.7 0.31 11.7 3.7 1.3 1 0 0 1 1 1 0 M protein repeat Gal4_dimer PF03902.13 KLO13051.1 - 0.2 11.9 1.8 0.31 11.2 1.8 1.3 1 0 0 1 1 1 0 Gal4-like dimerisation domain UDG PF03167.19 KLO13052.1 - 1.9e-17 63.7 0.1 7.1e-17 61.8 0.1 1.9 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily ADH_N PF08240.12 KLO13054.1 - 3.7e-25 87.9 4.1 7.1e-25 87.0 4.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO13054.1 - 1.7e-22 79.8 0.4 3.9e-22 78.6 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KLO13054.1 - 0.0091 15.3 0.1 0.016 14.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Cys_Met_Meta_PP PF01053.20 KLO13056.1 - 1.3e-127 425.5 0.0 1.7e-127 425.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 KLO13056.1 - 6.2e-12 45.6 2.6 3.7e-11 43.1 2.6 2.4 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KLO13056.1 - 4.9e-09 36.4 1.0 3.5e-07 30.5 0.1 2.6 1 1 1 2 2 2 1 GHMP kinases C terminal Met_gamma_lyase PF06838.11 KLO13056.1 - 0.00038 19.1 0.0 0.0009 17.9 0.0 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase GalKase_gal_bdg PF10509.9 KLO13056.1 - 0.00058 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Aminotran_1_2 PF00155.21 KLO13056.1 - 0.0017 17.6 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KLO13056.1 - 0.023 14.0 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KLO13056.1 - 0.025 13.9 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SelA PF03841.13 KLO13056.1 - 0.038 13.0 0.0 0.63 9.0 0.0 2.1 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase GDC-P PF02347.16 KLO13056.1 - 0.16 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Dioxygenase_C PF00775.21 KLO13057.1 - 5.7e-17 61.7 0.0 1.6e-16 60.3 0.0 1.7 1 1 0 1 1 1 1 Dioxygenase MG4 PF17789.1 KLO13057.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Macroglobulin domain MG4 F-box_4 PF15966.5 KLO13058.1 - 0.0057 16.5 0.0 1.8 8.5 0.0 2.9 2 0 0 2 2 2 2 F-box AAA_lid_5 PF17865.1 KLO13058.1 - 0.017 15.2 0.0 0.051 13.6 0.0 1.8 1 0 0 1 1 1 0 Midasin AAA lid domain F-box-like PF12937.7 KLO13058.1 - 0.087 12.7 0.0 0.087 12.7 0.0 2.6 2 1 0 2 2 2 0 F-box-like F-box PF00646.33 KLO13058.1 - 0.37 10.7 9.6 0.058 13.3 0.9 3.3 2 1 0 2 2 2 0 F-box domain LRR_4 PF12799.7 KLO13059.1 - 0.0084 16.5 2.7 17 6.0 0.0 4.5 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box PF00646.33 KLO13059.1 - 0.022 14.7 0.3 0.12 12.3 0.3 2.3 1 1 0 1 1 1 0 F-box domain F-box_4 PF15966.5 KLO13059.1 - 0.11 12.4 0.7 7.4 6.5 0.1 2.9 3 0 0 3 3 3 0 F-box UvrD_C PF13361.6 KLO13059.1 - 0.19 11.1 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Sde2_N_Ubi PF13019.6 KLO13060.1 - 8.5e-49 165.5 0.0 1.4e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain DUF1295 PF06966.12 KLO13061.1 - 1e-36 126.7 6.4 7.4e-36 123.8 6.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) zf-C2H2_8 PF15909.5 KLO13062.1 - 0.00011 22.4 7.1 0.00024 21.3 7.1 1.6 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 KLO13062.1 - 0.0021 18.8 15.8 0.028 15.3 0.6 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO13062.1 - 0.007 16.8 19.1 0.017 15.6 1.4 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KLO13062.1 - 0.13 12.9 0.6 0.13 12.9 0.6 2.4 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KLO13062.1 - 0.22 11.8 1.9 0.24 11.8 0.3 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding IMS PF00817.20 KLO13063.1 - 2.7e-35 121.6 0.0 4.9e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KLO13063.1 - 5.2e-15 56.2 0.0 3.8e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KLO13063.1 - 1.4e-07 31.0 7.3 8.5e-05 22.1 2.2 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KLO13063.1 - 0.0007 19.8 0.0 0.002 18.3 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif DUF1651 PF07864.11 KLO13063.1 - 0.012 15.9 0.0 0.045 14.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1651) GPR_Gpa2_C PF11970.8 KLO13065.1 - 0.0024 17.9 0.7 0.14 12.2 0.1 2.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KLO13065.1 - 0.08 12.3 1.8 0.095 12.0 1.8 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4781 PF16013.5 KLO13065.1 - 0.33 9.7 1.2 0.49 9.1 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) TrkA_TMD PF18613.1 KLO13065.1 - 0.82 9.2 5.5 2.4 7.7 5.5 1.8 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain CIA30 PF08547.12 KLO13066.1 - 1.3e-23 83.8 0.0 1.6e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Ras PF00071.22 KLO13067.1 - 1.1e-56 190.9 0.1 1.3e-56 190.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO13067.1 - 3.4e-20 72.5 0.0 6.2e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO13067.1 - 8.7e-10 38.3 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KLO13067.1 - 4.3e-05 23.1 0.0 8.5e-05 22.2 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KLO13067.1 - 0.00031 20.7 0.0 0.36 10.7 0.0 2.4 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KLO13067.1 - 0.0008 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KLO13067.1 - 0.007 16.2 1.3 0.094 12.5 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein ATPase PF06745.13 KLO13067.1 - 0.12 11.7 0.2 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 KLO13067.1 - 0.32 10.7 1.2 4.9 6.8 0.2 2.7 2 1 1 3 3 3 0 IstB-like ATP binding protein Pyr_redox_2 PF07992.14 KLO13068.1 - 8.3e-50 169.7 3.6 1.1e-49 169.3 3.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KLO13068.1 - 2e-17 62.9 0.0 3.8e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KLO13068.1 - 1.3e-09 38.4 5.6 2.4e-08 34.4 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO13068.1 - 2e-07 30.6 2.3 1.3e-05 24.6 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KLO13068.1 - 3.8e-07 30.6 0.0 8.3e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 KLO13068.1 - 7.2e-06 25.9 0.0 6.2e-05 22.9 0.0 2.4 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.6 KLO13068.1 - 2.7e-05 23.5 0.2 0.12 11.5 0.0 2.2 1 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KLO13068.1 - 0.032 14.7 0.3 0.16 12.4 0.2 2.2 1 1 1 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 KLO13068.1 - 0.083 11.6 0.9 23 3.5 0.2 3.0 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 KLO13068.1 - 0.085 12.8 0.3 4.5 7.3 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KLO13068.1 - 0.12 12.7 0.1 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DTC PF18102.1 KLO13069.1 - 0.095 12.8 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Deltex C-terminal domain DUF3499 PF12005.8 KLO13069.1 - 0.11 13.1 1.3 9.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Pro_CA PF00484.19 KLO13070.1 - 8e-37 126.9 0.7 1.7e-18 67.4 0.1 2.3 2 1 0 2 2 2 2 Carbonic anhydrase DNApol_Exo PF18136.1 KLO13070.1 - 0.097 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain RF-1 PF00472.20 KLO13071.1 - 1.6e-15 57.0 1.8 2.7e-15 56.3 1.8 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 KLO13071.1 - 0.0045 17.4 0.4 0.0071 16.8 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF4456 PF14644.6 KLO13071.1 - 0.012 15.3 2.5 0.021 14.5 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) AAA_2 PF07724.14 KLO13071.1 - 0.069 13.3 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) SLATT_5 PF18160.1 KLO13071.1 - 0.095 12.0 0.7 0.14 11.5 0.7 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 PHtD_u1 PF16645.5 KLO13071.1 - 0.11 12.9 2.8 1.8 9.0 0.1 2.9 3 0 0 3 3 3 0 Unstructured region on Pneumococcal histidine triad protein CA_like PF10563.9 KLO13071.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 Putative carbonic anhydrase Muted PF14942.6 KLO13071.1 - 0.32 11.3 3.8 0.41 11.0 2.9 1.6 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein HSBP1 PF06825.12 KLO13072.1 - 9e-16 57.5 3.6 1.2e-15 57.1 3.6 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 BORCS6 PF10157.9 KLO13072.1 - 0.00096 19.4 0.2 0.0012 19.1 0.2 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 PMC2NT PF08066.12 KLO13072.1 - 0.046 14.4 0.4 0.18 12.5 0.1 2.0 1 1 1 2 2 2 0 PMC2NT (NUC016) domain CR6_interact PF10147.9 KLO13073.1 - 0.00025 20.8 2.2 0.00025 20.8 2.2 2.5 2 0 0 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 NPR3 PF03666.13 KLO13073.1 - 4.3 6.0 30.6 0.006 15.4 8.9 2.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 PIN_3 PF13470.6 KLO13073.1 - 7 7.4 10.9 28 5.5 0.6 3.0 3 0 0 3 3 3 0 PIN domain CD34_antigen PF06365.12 KLO13074.1 - 0.0011 18.5 0.1 0.0017 18.0 0.1 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Rax2 PF12768.7 KLO13074.1 - 0.0021 17.5 0.4 0.0035 16.8 0.3 1.6 1 1 0 1 1 1 1 Cortical protein marker for cell polarity PIRT PF15099.6 KLO13076.1 - 0.77 9.3 4.0 2.1 7.9 0.0 2.9 2 1 1 3 3 3 0 Phosphoinositide-interacting protein family DUF5455 PF17537.2 KLO13078.1 - 0.013 15.9 0.4 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5455) stn_TNFRSF12A PF12191.8 KLO13078.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SKG6 PF08693.10 KLO13078.1 - 0.23 10.9 0.1 0.23 10.9 0.1 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 KLO13078.1 - 0.31 11.0 0.9 0.83 9.7 0.9 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif MSP1a PF11670.8 KLO13078.1 - 1.2 8.4 5.0 3.8 6.7 5.0 1.8 1 1 0 1 1 1 0 Major surface protein 1a (MSP1a) TMEM252 PF15664.5 KLO13079.1 - 0.0058 16.4 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Transmembrane protein 252 family PIRT PF15099.6 KLO13079.1 - 0.012 15.2 0.1 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Alpha_GJ PF03229.13 KLO13080.1 - 0.016 15.8 1.6 0.031 14.9 1.6 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF1180 PF06679.12 KLO13080.1 - 0.024 15.1 0.9 0.048 14.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PIRT PF15099.6 KLO13080.1 - 0.04 13.5 0.1 0.6 9.7 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Amnionless PF14828.6 KLO13080.1 - 0.074 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Amnionless FtsX PF02687.21 KLO13080.1 - 0.41 11.2 0.0 0.41 11.2 0.0 2.2 3 0 0 3 3 3 0 FtsX-like permease family PIRT PF15099.6 KLO13081.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family TIG PF01833.24 KLO13081.1 - 0.081 13.0 0.4 6.3 7.0 0.1 3.0 2 1 0 2 2 2 0 IPT/TIG domain SRTM1 PF15872.5 KLO13082.1 - 0.0022 18.1 1.2 0.0069 16.5 1.2 1.8 1 0 0 1 1 1 1 Serine-rich and transmembrane domain-containing protein 1 EphA2_TM PF14575.6 KLO13082.1 - 0.11 13.3 0.0 0.23 12.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1180 PF06679.12 KLO13082.1 - 0.16 12.3 0.6 0.28 11.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3104 PF11302.8 KLO13083.1 - 0.07 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) PIRT PF15099.6 KLO13084.1 - 0.033 13.8 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family EphA2_TM PF14575.6 KLO13084.1 - 0.081 13.8 0.0 0.15 12.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 KLO13084.1 - 0.092 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MtrF PF09472.10 KLO13084.1 - 0.36 10.2 1.2 25 4.4 0.2 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PIRT PF15099.6 KLO13086.1 - 0.048 13.2 0.2 11 5.6 0.0 2.5 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family Nitrate_red_gam PF02665.14 KLO13086.1 - 0.1 12.1 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF2434 PF10361.9 KLO13087.1 - 0.053 12.5 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) EphA2_TM PF14575.6 KLO13087.1 - 0.076 13.9 0.0 0.15 12.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KLO13087.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Nitrate_red_gam PF02665.14 KLO13088.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit F-box-like PF12937.7 KLO13090.1 - 5.4e-10 39.0 2.4 9.5e-10 38.2 0.3 2.4 2 0 0 2 2 2 1 F-box-like Mce4_CUP1 PF11887.8 KLO13090.1 - 0.0069 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative GDPD PF03009.17 KLO13090.1 - 0.0072 16.1 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family F-box PF00646.33 KLO13090.1 - 0.0082 16.0 0.5 0.0082 16.0 0.5 2.6 2 0 0 2 2 2 1 F-box domain LapA_dom PF06305.11 KLO13096.1 - 0.26 11.2 0.8 0.5 10.2 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 KLO13097.1 - 9.3e-29 100.4 13.0 9.3e-29 100.4 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tn7_Tnp_TnsA_C PF08721.11 KLO13099.1 - 0.13 12.9 0.0 0.39 11.4 0.0 1.8 1 0 0 1 1 1 0 TnsA endonuclease C terminal F-box-like PF12937.7 KLO13100.1 - 7.9e-09 35.3 0.0 1.8e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like Pox_A_type_inc PF04508.12 KLO13100.1 - 0.00064 19.5 0.1 1.2 9.1 0.0 2.7 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat Mce4_CUP1 PF11887.8 KLO13100.1 - 0.025 14.1 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative F-box PF00646.33 KLO13100.1 - 0.03 14.2 0.5 0.08 12.8 0.0 2.0 2 0 0 2 2 2 0 F-box domain SKI PF01202.22 KLO13101.1 - 3.5e-11 43.5 0.0 8.1e-08 32.5 0.0 2.7 1 1 1 2 2 2 2 Shikimate kinase AAA_18 PF13238.6 KLO13101.1 - 2.1e-05 25.1 0.0 0.00025 21.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KLO13101.1 - 3.5e-05 24.0 0.0 0.00035 20.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO13101.1 - 0.00014 22.3 0.1 0.00026 21.4 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain Cytidylate_kin2 PF13189.6 KLO13101.1 - 0.0049 17.0 0.0 0.014 15.5 0.0 1.7 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_17 PF13207.6 KLO13101.1 - 0.0052 17.2 0.0 0.34 11.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KLO13101.1 - 0.0066 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 KLO13101.1 - 0.0083 16.6 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KLO13101.1 - 0.02 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase ABC_tran PF00005.27 KLO13101.1 - 0.027 15.0 0.4 0.061 13.8 0.1 1.9 2 1 0 2 2 2 0 ABC transporter NACHT PF05729.12 KLO13101.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KLO13101.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KLO13101.1 - 0.094 13.0 0.1 0.28 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KLO13101.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PduV-EutP PF10662.9 KLO13101.1 - 0.13 12.0 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 KLO13101.1 - 0.15 11.9 0.0 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF2976 PF11190.8 KLO13103.1 - 1.4 8.8 6.0 0.28 11.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Polysacc_deac_1 PF01522.21 KLO13105.1 - 9.4e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KLO13105.1 - 0.00035 20.3 0.1 0.00081 19.1 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KLO13105.1 - 0.028 12.8 0.0 0.037 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) 7TM_GPCR_Srh PF10318.9 KLO13106.1 - 0.0028 16.8 4.8 0.0028 16.8 4.8 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srh p450 PF00067.22 KLO13107.1 - 3.1e-71 240.5 0.0 4.1e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ovate PF04844.13 KLO13107.1 - 0.039 13.9 0.1 0.097 12.7 0.1 1.6 1 0 0 1 1 1 0 Transcriptional repressor, ovate DUF5373 PF17343.2 KLO13109.1 - 1.1 9.1 10.2 1.3 8.9 9.4 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5373) TP53IP5 PF15331.6 KLO13113.1 - 1.7 8.7 6.2 3.4 7.8 6.2 1.5 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SOAR PF16533.5 KLO13114.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 STIM1 Orai1-activating region DUF1772 PF08592.11 KLO13114.1 - 2.5 8.4 6.8 3.5 7.9 4.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) ParG PF09274.10 KLO13115.1 - 0.041 14.0 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 ParG Tri3 PF07428.11 KLO13116.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 Tri3 PF07428.11 KLO13119.1 - 0.00026 20.1 0.0 0.0004 19.4 0.0 1.3 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 F-box-like PF12937.7 KLO13122.1 - 6.5e-10 38.7 0.0 6e-09 35.7 0.0 2.6 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.7 KLO13123.1 - 1.3e-17 63.4 0.1 1.1e-08 34.8 0.0 3.2 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KLO13123.1 - 6.2e-05 22.8 0.4 0.4 10.6 0.3 2.9 2 0 0 2 2 2 2 F-box domain Dickkopf_N PF04706.12 KLO13124.1 - 0.018 15.5 5.2 0.022 15.2 5.2 1.1 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Ferritin_2 PF13668.6 KLO13125.1 - 6.1e-38 130.1 0.0 9.9e-38 129.4 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Toxin_7 PF05980.12 KLO13126.1 - 0.1 12.8 3.9 0.21 11.9 3.9 1.5 1 0 0 1 1 1 0 Toxin 7 F-box-like PF12937.7 KLO13127.1 - 9.6e-09 35.0 0.2 2.4e-06 27.4 0.1 2.8 2 0 0 2 2 2 2 F-box-like DUF713 PF05218.14 KLO13127.1 - 0.0086 15.8 0.2 0.033 13.9 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF713) F-box PF00646.33 KLO13127.1 - 0.051 13.5 1.2 1.1 9.3 0.1 2.7 2 0 0 2 2 2 0 F-box domain Methyltransf_2 PF00891.18 KLO13130.1 - 1.2e-24 86.8 0.0 2.4e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_12 PF08242.12 KLO13130.1 - 0.00069 20.3 0.0 0.0013 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO13130.1 - 0.0044 17.7 0.0 0.0092 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO13130.1 - 0.009 15.8 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO13130.1 - 0.039 13.8 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RPA_C PF08784.11 KLO13130.1 - 0.047 14.4 0.0 0.1 13.3 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal Methyltransf_16 PF10294.9 KLO13130.1 - 0.055 13.2 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase MTS PF05175.14 KLO13130.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Dimerisation PF08100.11 KLO13130.1 - 0.11 12.6 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 Dimerisation domain p450 PF00067.22 KLO13132.1 - 1.4e-76 258.1 0.0 1.8e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Strabismus PF06638.11 KLO13132.1 - 0.18 10.4 0.5 0.26 9.9 0.5 1.1 1 0 0 1 1 1 0 Strabismus protein UbiA PF01040.18 KLO13133.1 - 1.1e-41 142.9 19.5 1.3e-41 142.6 19.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Wzy_C_2 PF11846.8 KLO13134.1 - 0.041 13.8 0.1 0.041 13.8 0.1 2.1 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal MFS_1 PF07690.16 KLO13139.1 - 2.8e-23 82.4 39.9 3.9e-23 81.9 33.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PMP22_Claudin PF00822.20 KLO13139.1 - 0.017 15.0 6.9 0.053 13.4 2.1 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family OSTbeta PF15048.6 KLO13140.1 - 0.16 12.1 3.5 4.5 7.4 0.1 2.6 2 1 0 2 2 2 0 Organic solute transporter subunit beta protein Wzy_C_2 PF11846.8 KLO13140.1 - 0.51 10.2 3.5 0.21 11.5 0.2 1.9 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal PHO4 PF01384.20 KLO13141.1 - 0.14 11.1 2.5 0.17 10.9 2.5 1.2 1 0 0 1 1 1 0 Phosphate transporter family Acetyltransf_9 PF13527.7 KLO13142.1 - 0.019 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NMT PF01233.19 KLO13142.1 - 0.042 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain PAH PF02671.21 KLO13143.1 - 1.8e-21 76.0 0.4 4e-14 52.5 0.0 2.7 2 1 0 2 2 2 2 Paired amphipathic helix repeat Ku_PK_bind PF08785.11 KLO13143.1 - 0.0082 16.3 0.2 5.6 7.1 0.1 2.5 2 0 0 2 2 2 2 Ku C terminal domain like PAH PF02671.21 KLO13144.1 - 2.4e-26 91.6 6.2 4.4e-14 52.3 0.0 2.6 2 1 1 3 3 3 2 Paired amphipathic helix repeat COX5A PF02284.16 KLO13144.1 - 0.02 14.9 0.0 0.67 10.0 0.1 2.4 2 1 0 2 2 2 0 Cytochrome c oxidase subunit Va Ku_PK_bind PF08785.11 KLO13144.1 - 0.03 14.5 0.2 7.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Ku C terminal domain like PAH PF02671.21 KLO13146.1 - 2.8e-09 37.0 0.4 4.8e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 Paired amphipathic helix repeat Toxin_37 PF11415.8 KLO13149.1 - 0.088 12.7 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Antifungal peptide termicin F-box-like PF12937.7 KLO13151.1 - 6.5e-07 29.2 0.4 2.4e-06 27.3 0.4 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO13151.1 - 0.38 10.7 3.8 2.7 8.0 0.5 3.2 2 0 0 2 2 2 0 F-box domain PAH PF02671.21 KLO13152.1 - 2.4e-08 34.0 0.0 4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Paired amphipathic helix repeat NADH-G_4Fe-4S_3 PF10588.9 KLO13153.1 - 0.0097 15.4 1.6 1.2 8.7 0.3 2.4 2 0 0 2 2 2 2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-C3HC4_3 PF13920.6 KLO13153.1 - 0.15 12.0 7.7 0.26 11.2 7.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.18 KLO13153.1 - 0.87 9.8 10.7 2 8.6 10.7 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_I PF00867.18 KLO13155.1 - 2.9e-14 53.2 0.0 5.9e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KLO13155.1 - 0.0003 21.2 0.0 0.00056 20.3 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain GEN1_C PF18380.1 KLO13155.1 - 0.091 13.7 0.0 0.16 12.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Phage_integrase PF00589.22 KLO13156.1 - 0.0082 16.0 0.0 0.8 9.5 0.0 2.9 3 0 0 3 3 3 1 Phage integrase family Phage_int_SAM_4 PF13495.6 KLO13156.1 - 0.15 12.6 0.0 1 9.9 0.0 2.1 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain SIR2 PF02146.17 KLO13157.1 - 1.4e-26 93.5 0.0 2e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Asparaginase PF00710.20 KLO13157.1 - 0.023 14.2 0.0 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 Asparaginase, N-terminal F-box-like PF12937.7 KLO13159.1 - 1.8e-07 30.9 1.8 2.4e-07 30.5 0.3 2.0 2 0 0 2 2 2 1 F-box-like Transferase PF02458.15 KLO13161.1 - 6.5e-05 21.8 0.0 9.7e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 KLO13161.1 - 0.0027 16.5 0.0 0.0086 14.8 0.0 1.6 2 0 0 2 2 2 1 Condensation domain F-box-like PF12937.7 KLO13162.1 - 0.0003 20.6 0.3 0.00085 19.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO13162.1 - 0.53 10.8 2.9 14 6.2 2.3 3.1 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO13163.1 - 1.5e-07 31.2 0.5 1.5e-07 31.2 0.5 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO13163.1 - 4.3 7.3 6.8 15 5.6 3.3 3.4 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO13165.1 - 8e-05 22.5 0.3 0.00074 19.4 0.1 2.7 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO13165.1 - 0.0066 16.8 0.6 33 5.1 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box PF00646.33 KLO13165.1 - 0.025 14.5 2.6 13 5.8 0.2 3.8 3 0 0 3 3 3 0 F-box domain GST_C PF00043.25 KLO13165.1 - 0.18 12.1 0.3 0.7 10.1 0.1 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Transferase PF02458.15 KLO13166.1 - 0.00019 20.2 0.0 0.00085 18.1 0.0 1.8 2 0 0 2 2 2 1 Transferase family Condensation PF00668.20 KLO13166.1 - 0.085 11.5 0.0 0.16 10.6 0.0 1.4 2 0 0 2 2 2 0 Condensation domain F-box-like PF12937.7 KLO13167.1 - 1.1e-05 25.2 0.1 2.9e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO13168.1 - 9.4e-06 25.4 0.8 3e-05 23.8 0.8 2.0 1 0 0 1 1 1 1 F-box-like DSPc PF00782.20 KLO13169.1 - 1.2e-25 89.9 0.0 1.4e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KLO13169.1 - 0.00013 21.7 0.0 0.00015 21.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTS_IIB PF02302.17 KLO13169.1 - 0.12 13.1 0.0 0.32 11.7 0.0 1.7 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit EamA PF00892.20 KLO13172.1 - 1.9 8.7 14.0 5 7.3 14.0 1.7 1 1 0 1 1 1 0 EamA-like transporter family Retrotran_gag_3 PF14244.6 KLO13173.1 - 0.0015 18.3 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Phage_capsid PF05065.13 KLO13173.1 - 0.042 13.2 0.0 0.052 12.8 0.0 1.1 1 0 0 1 1 1 0 Phage capsid family DSPc PF00782.20 KLO13174.1 - 1.7e-28 99.1 0.0 2.3e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KLO13174.1 - 0.00018 21.2 0.0 0.00021 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DHR-2 PF06920.13 KLO13174.1 - 0.079 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Dock homology region 2 DSPc PF00782.20 KLO13176.1 - 6.1e-29 100.5 0.0 7.7e-29 100.2 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KLO13176.1 - 3.6e-05 23.4 0.0 4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KLO13176.1 - 0.05 13.9 0.3 0.14 12.4 0.3 1.8 1 1 0 1 1 1 0 Rit1 DUSP-like domain LRR_4 PF12799.7 KLO13177.1 - 0.0022 18.4 3.2 3.3 8.3 0.0 4.5 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO13177.1 - 0.0061 16.4 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like OmpH PF03938.14 KLO13177.1 - 0.41 11.0 3.1 10 6.4 0.1 2.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Zn_clus PF00172.18 KLO13178.1 - 2.6e-18 65.9 25.3 4.7e-09 36.2 9.0 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Septin PF00735.18 KLO13178.1 - 1.2e-10 41.1 0.0 1.7e-07 30.8 0.0 4.3 5 0 0 5 5 5 1 Septin DUF2457 PF10446.9 KLO13179.1 - 1.1 8.4 7.6 1.4 8.0 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Methyltransf_2 PF00891.18 KLO13187.1 - 2.5e-20 72.7 0.0 1.2e-19 70.4 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation PF08100.11 KLO13187.1 - 0.0032 17.5 0.0 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_25 PF13649.6 KLO13187.1 - 0.036 14.8 0.0 0.084 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KLO13187.1 - 0.05 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KLO13188.1 - 1.1e-19 70.5 0.0 4.6e-19 68.5 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation PF08100.11 KLO13188.1 - 0.0038 17.2 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain MTS PF05175.14 KLO13188.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KLO13188.1 - 0.077 13.7 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KLO13188.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase UbiA PF01040.18 KLO13193.1 - 2.7e-29 102.2 18.5 3.4e-29 101.9 18.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family UbiA PF01040.18 KLO13194.1 - 5e-15 55.5 11.4 5.9e-15 55.3 11.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 KLO13195.1 - 5.3e-65 220.0 0.0 6.1e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3083 PF11281.8 KLO13195.1 - 0.043 13.1 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) Thermopsin PF05317.11 KLO13196.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Thermopsin SARS_3b PF12383.8 KLO13197.1 - 0.034 14.3 5.0 0.06 13.5 1.6 2.2 2 0 0 2 2 2 0 Severe acute respiratory syndrome coronavirus 3b protein p450 PF00067.22 KLO13198.1 - 3.6e-70 237.0 0.0 4.1e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 KLO13199.1 - 3.2e-21 75.6 0.0 2.9e-18 65.9 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain HCV_NS5a_C PF12941.7 KLO13199.1 - 0.026 14.4 0.1 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region Rrf2 PF02082.20 KLO13199.1 - 0.031 14.6 0.0 0.51 10.7 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator Dimerisation PF08100.11 KLO13199.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain MarR_2 PF12802.7 KLO13199.1 - 0.058 13.3 0.0 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 MarR family Methyltransf_25 PF13649.6 KLO13199.1 - 0.06 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HTH_IclR PF09339.10 KLO13199.1 - 0.12 12.2 0.0 0.59 10.0 0.0 2.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain Methyltransf_2 PF00891.18 KLO13200.1 - 1.1e-23 83.6 0.0 5.3e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_12 PF08242.12 KLO13200.1 - 0.00027 21.6 0.0 0.00075 20.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO13200.1 - 0.00064 19.3 0.1 0.0065 16.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KLO13200.1 - 0.0054 17.4 0.0 0.017 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO13200.1 - 0.015 15.1 0.0 0.06 13.1 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Dimerisation PF08100.11 KLO13200.1 - 0.019 15.0 0.0 0.052 13.6 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_23 PF13489.6 KLO13200.1 - 0.025 14.4 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain YqbF PF14553.6 KLO13200.1 - 0.05 13.5 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 YqbF, hypothetical protein domain Methyltransf_4 PF02390.17 KLO13200.1 - 0.083 12.4 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase p450 PF00067.22 KLO13201.1 - 1.4e-65 221.9 0.0 1.8e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 KLO13203.1 - 1.5e-22 79.9 0.0 2.7e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_12 PF08242.12 KLO13203.1 - 0.00063 20.4 0.0 0.0012 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO13203.1 - 0.003 17.4 0.0 0.0074 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO13203.1 - 0.0041 16.7 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KLO13203.1 - 0.0073 17.0 0.0 0.015 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.11 KLO13203.1 - 0.048 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_23 PF13489.6 KLO13203.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RPA_C PF08784.11 KLO13203.1 - 0.11 13.1 0.0 0.3 11.8 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal Methyltransf_4 PF02390.17 KLO13203.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase adh_short_C2 PF13561.6 KLO13204.1 - 1.1e-43 149.5 4.6 2.2e-43 148.5 4.6 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO13204.1 - 1.2e-39 135.8 5.1 3.9e-39 134.1 5.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO13204.1 - 5.8e-12 45.9 0.7 8.3e-12 45.4 0.7 1.3 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 KLO13204.1 - 0.059 13.5 0.8 0.13 12.4 0.7 1.7 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 KLO13204.1 - 0.068 12.6 0.9 0.14 11.6 0.1 1.9 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family Trp_halogenase PF04820.14 KLO13206.1 - 2.4e-34 119.0 0.7 5.2e-19 68.4 0.5 2.6 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KLO13206.1 - 1.1e-16 61.1 0.0 2.6e-16 59.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO13206.1 - 7.8e-09 35.2 0.4 3.7e-07 29.7 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO13206.1 - 9.1e-07 28.8 0.4 0.027 14.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KLO13206.1 - 9.2e-06 25.3 0.0 1.8e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KLO13206.1 - 0.00023 20.0 0.1 0.0028 16.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KLO13206.1 - 0.00053 19.2 0.0 0.00089 18.4 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KLO13206.1 - 0.00055 19.1 0.1 0.0024 17.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KLO13206.1 - 0.0011 19.2 1.6 0.0017 18.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KLO13206.1 - 0.0075 16.8 0.2 4 8.1 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO13206.1 - 0.053 12.8 0.0 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 Thi4 family p450 PF00067.22 KLO13207.1 - 9.8e-68 229.0 0.0 1.2e-67 228.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3083 PF11281.8 KLO13207.1 - 0.025 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) Pyr_redox_3 PF13738.6 KLO13208.1 - 3.7e-21 75.7 0.0 1.5e-19 70.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KLO13208.1 - 4.9e-21 74.8 0.0 2.8e-20 72.2 0.0 2.1 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KLO13208.1 - 8.5e-16 58.0 0.2 3.8e-12 46.0 0.1 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KLO13208.1 - 8.2e-15 54.8 0.0 6.8e-12 45.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KLO13208.1 - 4.3e-06 26.8 0.0 0.0037 17.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KLO13208.1 - 4.9e-06 26.0 1.1 0.0095 15.3 0.0 3.0 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KLO13208.1 - 1e-05 26.0 0.4 0.077 13.6 0.2 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KLO13208.1 - 2.3e-05 24.6 0.1 0.02 15.1 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain DAO PF01266.24 KLO13208.1 - 3.9e-05 23.4 0.1 0.46 10.0 0.0 3.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KLO13208.1 - 0.00015 21.1 0.1 0.07 12.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 KLO13208.1 - 0.00026 19.8 1.1 0.0059 15.4 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.6 KLO13208.1 - 0.0004 20.4 1.9 0.36 10.8 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KLO13208.1 - 0.00051 20.2 0.2 0.0027 17.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.17 KLO13208.1 - 0.0032 18.0 0.0 0.65 10.6 0.0 3.1 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 KLO13208.1 - 0.005 15.9 0.3 0.12 11.4 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein ApbA PF02558.16 KLO13208.1 - 0.0081 15.8 0.0 1.6 8.3 0.0 2.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KLO13208.1 - 0.011 14.8 0.0 0.58 9.2 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.22 KLO13208.1 - 0.015 14.4 1.3 1.7 7.6 0.0 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KLO13208.1 - 0.016 14.5 0.1 0.069 12.4 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KLO13208.1 - 0.021 14.1 0.1 0.93 8.7 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain CoA_binding PF02629.19 KLO13208.1 - 0.037 14.7 0.1 14 6.4 0.0 2.5 2 0 0 2 2 2 0 CoA binding domain DUF498 PF04430.14 KLO13208.1 - 0.058 13.5 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF498/DUF598) 3HCDH_N PF02737.18 KLO13208.1 - 0.068 13.0 0.4 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SoxE PF06525.11 KLO13208.1 - 0.14 11.6 0.3 0.43 10.0 0.3 1.7 1 0 0 1 1 1 0 Sulfocyanin (SoxE) domain UbiA PF01040.18 KLO13209.1 - 2.6e-44 151.4 17.0 3.4e-44 151.0 17.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Methyltransf_2 PF00891.18 KLO13212.1 - 1e-19 70.7 0.0 5.1e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation PF08100.11 KLO13212.1 - 0.071 13.1 0.1 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Dimerisation domain MTS PF05175.14 KLO13212.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KLO13212.1 - 0.13 13.0 0.0 0.3 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 KLO13216.1 - 8.9e-24 84.3 3.0 1.2e-23 83.9 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO13216.1 - 2e-16 60.1 0.4 2.7e-16 59.6 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 KLO13216.1 - 0.0019 17.5 0.7 0.0033 16.8 0.7 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 KLO13216.1 - 0.0057 16.6 0.9 0.011 15.7 0.9 1.5 1 0 0 1 1 1 1 KR domain GRDA PF04723.14 KLO13216.1 - 0.022 14.5 0.9 0.71 9.6 0.9 2.4 1 1 0 1 1 1 0 Glycine reductase complex selenoprotein A Eno-Rase_NADH_b PF12242.8 KLO13216.1 - 0.034 13.9 0.8 0.075 12.8 0.8 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.6 KLO13216.1 - 0.041 14.3 0.8 0.075 13.5 0.3 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding ADH_zinc_N PF00107.26 KLO13216.1 - 0.078 13.0 1.1 0.17 11.8 1.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_2 PF00891.18 KLO13218.1 - 3.6e-18 65.6 0.0 9.5e-17 61.0 0.0 2.2 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KLO13218.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Dimerisation PF08100.11 KLO13218.1 - 0.033 14.2 0.0 0.094 12.7 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_25 PF13649.6 KLO13218.1 - 0.035 14.8 0.0 0.43 11.3 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain DUF938 PF06080.12 KLO13218.1 - 0.082 12.7 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_12 PF08242.12 KLO13218.1 - 0.14 13.0 0.0 0.64 10.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 KLO13218.1 - 0.19 11.2 0.0 0.4 10.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Acetyltransf_3 PF13302.7 KLO13219.1 - 2.3e-08 34.8 0.0 2.9e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CENP-B_dimeris PF09026.10 KLO13220.1 - 0.027 14.8 9.0 0.5 10.8 2.7 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Exotox-A_cataly PF09009.10 KLO13220.1 - 0.14 11.9 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Exotoxin A catalytic TMF_TATA_bd PF12325.8 KLO13220.1 - 0.84 9.9 9.2 1.5 9.1 0.8 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3188 PF11384.8 KLO13221.1 - 0.3 10.8 4.1 1.5 8.6 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) Glyco_hydro_63 PF03200.16 KLO13223.1 - 1.7e-164 548.2 0.0 1.3e-163 545.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KLO13223.1 - 2e-77 260.3 0.0 8.5e-77 258.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KLO13223.1 - 0.00082 18.3 0.0 0.0013 17.6 0.0 1.3 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 KLO13223.1 - 0.15 10.9 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase F-box-like PF12937.7 KLO13226.1 - 0.068 13.1 0.2 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KLO13226.1 - 0.098 12.6 0.2 0.26 11.2 0.2 1.7 1 0 0 1 1 1 0 F-box domain dsrm PF00035.26 KLO13227.1 - 3.5e-10 40.4 0.0 3.8e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KLO13227.1 - 0.0041 17.3 0.6 0.021 15.1 0.6 1.8 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 DUF4260 PF14079.6 KLO13227.1 - 0.13 12.3 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) Dicer_dimer PF03368.14 KLO13227.1 - 0.13 12.4 0.4 0.3 11.3 0.4 1.6 1 1 0 1 1 1 0 Dicer dimerisation domain dsrm PF00035.26 KLO13228.1 - 6.6e-10 39.6 0.0 7.1e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KLO13228.1 - 6.5e-05 23.1 1.1 0.0005 20.3 1.1 1.9 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Dicer_dimer PF03368.14 KLO13228.1 - 0.14 12.3 0.4 0.32 11.2 0.4 1.6 1 1 0 1 1 1 0 Dicer dimerisation domain dsrm PF00035.26 KLO13229.1 - 5.9e-10 39.7 0.1 7.8e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KLO13229.1 - 0.013 15.8 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 ADIP PF11559.8 KLO13230.1 - 4.5e-19 69.0 10.4 4.5e-19 69.0 10.4 2.9 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Lectin_N PF03954.14 KLO13230.1 - 0.0071 16.1 8.3 0.57 9.9 5.7 2.6 2 0 0 2 2 2 2 Hepatic lectin, N-terminal domain DUF720 PF05302.11 KLO13230.1 - 0.24 11.2 4.7 0.51 10.2 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF720) LMBR1 PF04791.16 KLO13230.1 - 0.5 9.2 5.8 0.13 11.2 1.7 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein AIP3 PF03915.13 KLO13230.1 - 0.6 9.1 10.0 0.061 12.4 5.2 1.6 2 0 0 2 2 2 0 Actin interacting protein 3 Exonuc_VII_L PF02601.15 KLO13230.1 - 1.9 8.0 9.3 0.29 10.7 4.7 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit OmpH PF03938.14 KLO13230.1 - 2.7 8.3 9.2 9 6.6 9.2 1.9 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 KLO13230.1 - 4.7 6.4 7.4 11 5.2 7.4 1.5 1 0 0 1 1 1 0 TMPIT-like protein Mod_r PF07200.13 KLO13230.1 - 8.9 6.4 16.7 2 8.5 12.6 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein dsrm PF00035.26 KLO13231.1 - 1.4e-08 35.3 0.0 1.6e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KLO13231.1 - 0.078 13.2 0.6 0.59 10.4 0.6 1.9 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KLO13233.1 - 1.4e-10 41.7 0.5 1.6e-10 41.5 0.5 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif Peptidase_C97 PF05903.14 KLO13233.1 - 0.015 15.1 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 PPPDE putative peptidase domain DUF2188 PF09954.9 KLO13233.1 - 0.02 15.0 0.8 0.031 14.4 0.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Secapin PF17521.2 KLO13234.1 - 0.13 12.1 2.2 0.55 10.1 0.2 2.4 2 0 0 2 2 2 0 Honey bee peptides PAP2 PF01569.21 KLO13235.1 - 1.6e-12 47.4 11.7 2.2e-12 46.9 10.4 1.9 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 KLO13235.1 - 0.0019 18.4 0.1 0.05 13.7 0.0 2.5 2 1 0 2 2 2 1 Divergent PAP2 family DUF4451 PF14616.6 KLO13236.1 - 1.7e-05 25.0 1.9 1.1 9.5 0.1 3.2 2 1 1 3 3 3 3 Domain of unknown function (DUF4451) DiS_P_DiS PF06750.13 KLO13236.1 - 0.014 15.5 1.7 0.018 15.2 0.1 1.9 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Eapp_C PF10238.9 KLO13236.1 - 0.69 10.0 3.6 15 5.6 1.8 2.9 2 1 0 2 2 2 0 E2F-associated phosphoprotein Glyco_hyd_65N_2 PF14498.6 KLO13238.1 - 3.9e-44 151.3 0.1 5.9e-44 150.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain PGM_PMM_I PF02878.16 KLO13239.1 - 2e-36 124.7 0.1 3.1e-36 124.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KLO13239.1 - 4.6e-26 91.2 0.0 1.7e-25 89.5 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KLO13239.1 - 1.8e-13 51.0 0.0 5.7e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KLO13239.1 - 0.00072 19.7 0.0 0.002 18.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Acetyltransf_3 PF13302.7 KLO13240.1 - 2.2e-09 38.1 0.0 2.9e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KLO13241.1 - 2.5e-10 41.2 0.0 3.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KLO13242.1 - 4.4e-10 40.4 0.0 6.2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KLO13243.1 - 1.2e-08 35.7 0.0 1.6e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Carb_kinase PF01256.17 KLO13244.1 - 1.5e-49 168.6 0.0 1.9e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KLO13244.1 - 0.0025 17.3 0.0 0.005 16.2 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DOPA_dioxygen PF08883.11 KLO13245.1 - 5.9e-38 129.3 0.0 9.8e-38 128.6 0.0 1.4 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF383 PF04063.14 KLO13247.1 - 1e-55 188.4 0.0 4.5e-55 186.3 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KLO13247.1 - 4.7e-19 68.0 0.2 9e-19 67.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Cnd1 PF12717.7 KLO13247.1 - 0.016 15.3 1.2 0.67 10.0 0.0 2.8 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KLO13247.1 - 0.04 14.2 0.0 0.25 11.7 0.0 2.4 1 0 0 1 1 1 0 HEAT repeat Spt20 PF12090.8 KLO13248.1 - 9.6e-27 94.1 0.4 5.1e-16 59.0 0.0 2.2 1 1 1 2 2 2 2 Spt20 family GATA PF00320.27 KLO13249.1 - 1.1e-14 53.7 1.6 2e-14 52.9 1.6 1.4 1 0 0 1 1 1 1 GATA zinc finger Nudix_N_2 PF14803.6 KLO13249.1 - 0.25 11.3 0.8 0.73 9.8 0.8 1.8 1 0 0 1 1 1 0 Nudix N-terminal CCDC14 PF15254.6 KLO13250.1 - 0.02 13.6 0.1 0.03 13.0 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 DEAD PF00270.29 KLO13252.1 - 5.6e-47 159.8 0.0 9.8e-47 159.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO13252.1 - 3.6e-31 107.8 0.0 1e-30 106.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO13252.1 - 0.00082 19.4 0.0 0.0022 18.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KLO13252.1 - 0.043 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KLO13252.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 KLO13252.1 - 0.2 10.4 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Cofilin_ADF PF00241.20 KLO13253.1 - 7.2e-07 29.0 0.0 1.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PH PF00169.29 KLO13253.1 - 0.00014 22.3 0.0 0.00047 20.6 0.0 1.9 1 0 0 1 1 1 1 PH domain DUF1295 PF06966.12 KLO13254.1 - 8.4e-48 162.9 1.8 1.3e-47 162.3 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KLO13254.1 - 2.2e-05 24.8 1.2 5.9e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 KLO13254.1 - 0.044 13.8 0.0 0.044 13.8 0.0 2.9 3 1 1 4 4 4 0 3-oxo-5-alpha-steroid 4-dehydrogenase Mus7 PF09462.10 KLO13255.1 - 2.4e-69 234.8 0.0 3.2e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family Acetyltransf_7 PF13508.7 KLO13256.1 - 0.02 15.3 0.0 0.057 13.8 0.0 1.8 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KLO13256.1 - 0.029 14.4 0.1 0.072 13.2 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain LRR_8 PF13855.6 KLO13257.1 - 2.2e-06 27.3 7.2 0.012 15.4 1.6 2.6 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KLO13257.1 - 0.00025 21.3 6.3 0.00032 21.0 0.4 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) DLH PF01738.18 KLO13262.1 - 2.7e-19 69.6 0.0 3.5e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family adh_short PF00106.25 KLO13263.1 - 2.4e-36 125.1 0.1 2.8e-36 124.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO13263.1 - 5e-33 114.6 0.1 6.3e-33 114.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO13263.1 - 9.2e-11 42.0 0.6 2.3e-10 40.6 0.6 1.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KLO13263.1 - 0.067 12.2 0.2 0.093 11.7 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AraC_binding_2 PF14525.6 KLO13263.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 AraC-binding-like domain Glutaredoxin PF00462.24 KLO13264.1 - 1.1e-16 60.7 0.0 1.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin LEDGF PF11467.8 KLO13265.1 - 2.9e-05 23.7 0.2 4.3e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) Med26 PF08711.11 KLO13265.1 - 0.0013 18.7 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Helicase_IV_N PF12462.8 KLO13265.1 - 0.16 11.9 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal MFS_1 PF07690.16 KLO13266.1 - 2.3e-31 109.0 41.0 4.1e-30 104.9 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.13 KLO13266.1 - 0.5 11.0 3.4 0.21 12.2 0.2 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Abhydrolase_6 PF12697.7 KLO13267.1 - 2.7e-07 31.4 0.1 3.6e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KLO13268.1 - 6.4e-10 40.0 0.1 8.2e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KLO13269.1 - 1.5e-08 35.5 0.1 2.3e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KLO13271.1 - 7.5e-09 36.5 0.1 1.2e-08 35.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KLO13271.1 - 0.038 12.9 0.0 0.078 11.9 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KLO13272.1 - 7.8e-11 43.0 0.2 1.3e-10 42.2 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO13272.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO13273.1 - 8.5e-12 46.1 0.0 1.2e-11 45.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO13273.1 - 0.015 14.9 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold RabGAP-TBC PF00566.18 KLO13275.1 - 3.1e-46 157.7 0.1 4.6e-46 157.2 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 KLO13275.1 - 6.8e-06 26.4 0.4 0.00068 20.0 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KLO13275.1 - 1.9e-05 24.2 2.0 0.001 18.8 0.3 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KLO13275.1 - 0.00014 21.2 0.8 0.00093 18.6 0.2 2.6 2 0 0 2 2 2 1 EF hand GRAM PF02893.20 KLO13275.1 - 0.0021 17.9 0.0 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 GRAM domain EF-hand_5 PF13202.6 KLO13275.1 - 0.014 14.9 0.2 0.045 13.3 0.2 1.9 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KLO13275.1 - 0.014 15.2 1.5 0.15 12.0 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KLO13275.1 - 0.052 13.9 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region HSP70 PF00012.20 KLO13277.1 - 3.7e-05 22.1 0.0 8.4e-05 21.0 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein RicinB_lectin_2 PF14200.6 KLO13278.1 - 1.3e-05 25.8 10.7 0.00056 20.6 1.5 2.2 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Inhibitor_I66 PF16850.5 KLO13278.1 - 5e-05 23.2 1.8 7.8e-05 22.6 1.8 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I66 GluRS_N PF18466.1 KLO13278.1 - 0.018 15.4 0.5 0.28 11.6 0.0 2.5 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain DUF11 PF01345.18 KLO13278.1 - 0.028 14.7 2.9 0.028 14.7 2.9 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF11 NlpE PF04170.12 KLO13278.1 - 0.18 12.8 0.9 0.73 10.8 0.2 2.3 2 1 0 2 2 2 0 NlpE N-terminal domain MetallophosN PF16371.5 KLO13278.1 - 0.51 10.6 4.2 17 5.7 0.3 3.0 2 1 1 3 3 3 0 N terminal of Calcineurin-like phosphoesterase HSP70 PF00012.20 KLO13279.1 - 0.25 9.5 0.0 1.8 6.6 0.0 1.9 2 0 0 2 2 2 0 Hsp70 protein RicinB_lectin_2 PF14200.6 KLO13280.1 - 6.3e-05 23.6 9.4 0.00034 21.3 2.7 3.0 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Inhibitor_I66 PF16850.5 KLO13280.1 - 0.00031 20.6 2.0 0.0004 20.3 0.4 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I66 RicinB_lectin_2 PF14200.6 KLO13281.1 - 0.00013 22.6 9.3 0.0029 18.3 2.5 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Y_Y_Y PF07495.13 KLO13281.1 - 0.033 14.1 0.7 0.62 10.1 0.1 2.7 3 0 0 3 3 3 0 Y_Y_Y domain Inhibitor_I48 PF10467.9 KLO13281.1 - 0.058 13.3 0.3 0.087 12.7 0.3 1.3 1 1 0 1 1 1 0 Peptidase inhibitor clitocypin Pkinase_fungal PF17667.1 KLO13282.1 - 1.2e-59 202.2 0.0 4.1e-59 200.4 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO13282.1 - 1.8e-05 24.2 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13282.1 - 0.022 14.1 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 KLO13282.1 - 0.037 13.4 0.1 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 4HBT_2 PF13279.6 KLO13283.1 - 8.5e-18 65.0 0.0 1.3e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KLO13283.1 - 6.8e-07 29.5 0.0 1.4e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KLO13283.1 - 0.00022 20.6 0.1 0.0015 17.8 0.2 1.9 2 0 0 2 2 2 1 Acyl-ACP thioesterase PDCD2_C PF04194.13 KLO13284.1 - 2.4e-42 145.0 0.1 2.4e-42 145.0 0.1 3.4 4 0 0 4 4 4 1 Programmed cell death protein 2, C-terminal putative domain Nop14 PF04147.12 KLO13284.1 - 0.019 13.2 4.0 0.037 12.3 4.0 1.4 1 0 0 1 1 1 0 Nop14-like family FlpD PF02662.16 KLO13284.1 - 1.4 9.0 3.4 1.1 9.3 0.3 2.0 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit Presenilin PF01080.17 KLO13284.1 - 2 7.1 3.9 3.2 6.4 3.9 1.3 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 KLO13284.1 - 6.5 4.7 10.7 14 3.6 10.7 1.5 1 0 0 1 1 1 0 DNA polymerase phi PIG-F PF06699.11 KLO13285.1 - 9.3e-35 120.4 4.0 1.5e-34 119.8 4.0 1.3 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Ion_trans PF00520.31 KLO13285.1 - 0.04 13.2 0.3 0.052 12.8 0.3 1.3 1 0 0 1 1 1 0 Ion transport protein Cation_efflux PF01545.21 KLO13286.1 - 7.5e-43 146.6 28.5 7.5e-43 146.6 28.5 3.4 3 1 0 3 3 3 1 Cation efflux family Ribosomal_L23 PF00276.20 KLO13287.1 - 4e-11 43.1 0.1 1.2e-10 41.6 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L23 DUF3490 PF11995.8 KLO13287.1 - 0.084 12.7 7.5 0.029 14.2 4.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3490) Flavin_Reduct PF01613.18 KLO13288.1 - 5.2e-30 104.6 0.1 6.7e-30 104.2 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DNA_pol_B PF00136.21 KLO13289.1 - 4.5e-118 394.9 0.2 6e-118 394.5 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KLO13289.1 - 2.8e-60 203.2 0.5 5.5e-60 202.3 0.5 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KLO13289.1 - 2.9e-32 112.2 0.0 1.8e-31 109.5 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KLO13289.1 - 3.1e-20 72.0 6.2 8e-20 70.7 6.2 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KLO13289.1 - 0.013 14.4 0.0 0.035 13.0 0.0 1.6 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral tRNA_NucTran2_2 PF13735.6 KLO13289.1 - 0.016 15.2 0.2 0.034 14.1 0.2 1.5 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Metallophos PF00149.28 KLO13290.1 - 9.1e-14 52.4 0.0 2.6e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KLO13290.1 - 2.8e-05 24.4 0.1 0.005 17.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_16 PF00722.21 KLO13291.1 - 4e-27 94.8 0.1 5.9e-27 94.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.18 KLO13292.1 - 5.4e-19 68.2 0.6 1.1e-18 67.3 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO13292.1 - 4e-05 23.6 9.9 7.4e-05 22.8 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1926 PF09095.11 KLO13294.1 - 0.025 14.2 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1926) AP3D1 PF06375.11 KLO13294.1 - 0.081 13.2 5.8 0.1 12.9 5.8 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Fungal_trans PF04082.18 KLO13295.1 - 2e-17 63.1 1.1 3.6e-17 62.3 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO13295.1 - 2.2e-05 24.5 12.6 4e-05 23.6 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KLO13295.1 - 2.4 8.0 15.7 3.8 7.4 15.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit APC_u15 PF16636.5 KLO13295.1 - 7.6 7.0 5.9 17 5.9 5.9 1.5 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 RNA_pol_Rbc25 PF08292.12 KLO13296.1 - 4.7e-30 104.5 0.0 6.8e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KLO13296.1 - 1.7e-20 73.2 0.1 2.7e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Mito_carr PF00153.27 KLO13297.1 - 3.1e-62 206.5 3.5 7.2e-21 73.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KLO13297.1 - 0.0015 17.8 0.5 0.32 10.1 0.0 2.9 3 0 0 3 3 3 2 Gammaproteobacterial serine protease MMR_HSR1 PF01926.23 KLO13298.1 - 3e-15 56.3 0.0 4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KLO13298.1 - 1.7e-06 28.2 0.0 0.00098 19.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 KLO13298.1 - 0.0031 17.1 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KLO13298.1 - 0.0044 16.9 0.1 0.01 15.7 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KLO13298.1 - 0.022 14.1 0.0 0.033 13.5 0.0 1.4 1 1 0 1 1 1 0 AIG1 family Septin PF00735.18 KLO13298.1 - 0.066 12.5 0.1 2.1 7.5 0.0 2.5 2 1 0 2 2 2 0 Septin ABC_tran PF00005.27 KLO13298.1 - 0.078 13.5 0.2 0.55 10.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KLO13298.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain F-box-like PF12937.7 KLO13299.1 - 2.4e-05 24.2 0.6 8.7e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 F-box-like TMF_DNA_bd PF12329.8 KLO13300.1 - 0.38 10.8 6.0 1.1 9.3 1.2 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF724 PF05266.14 KLO13300.1 - 1.4 8.7 5.7 0.24 11.2 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF724) ATG16 PF08614.11 KLO13300.1 - 1.5 9.0 17.1 1.1 9.4 8.6 2.9 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) TRAF_BIRC3_bd PF16673.5 KLO13300.1 - 7.6 6.4 6.1 4.5 7.1 0.3 2.6 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF1771 PF08590.10 KLO13301.1 - 9.7e-16 57.9 8.8 2.1e-15 56.8 8.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KLO13301.1 - 2.3e-09 37.0 8.5 3.8e-07 29.9 1.4 2.8 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KLO13301.1 - 4.8e-09 35.9 7.8 2.7e-06 27.1 0.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KLO13301.1 - 1.3e-08 35.4 3.6 5.1e-07 30.4 0.1 2.5 1 1 1 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 KLO13301.1 - 1.3e-05 24.9 12.1 0.0009 19.0 1.0 3.0 2 1 0 2 2 2 2 CCCH-type zinc finger Smr PF01713.21 KLO13301.1 - 2.2e-05 24.7 0.0 7.1e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Smr domain zf-CCCH_2 PF14608.6 KLO13301.1 - 0.0001 22.6 6.1 0.043 14.3 1.4 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 KLO13301.1 - 0.00033 20.3 2.9 0.035 13.8 0.3 2.4 2 0 0 2 2 2 2 Putative zinc-finger domain zf-CCCH_3 PF15663.5 KLO13301.1 - 0.0017 18.6 3.4 0.48 10.7 0.1 2.3 1 1 1 2 2 2 2 Zinc-finger containing family HBS1_N PF08938.10 KLO13301.1 - 0.64 10.4 0.0 0.64 10.4 0.0 2.5 3 0 0 3 3 3 0 HBS1 N-terminus HD_3 PF13023.6 KLO13303.1 - 3.2e-40 137.8 0.1 4.1e-40 137.4 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KLO13303.1 - 5.5e-08 32.8 0.2 1e-07 31.9 0.2 1.5 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KLO13303.1 - 3e-06 27.4 0.2 7.3e-06 26.2 0.2 1.7 1 1 0 1 1 1 1 HD domain AICARFT_IMPCHas PF01808.18 KLO13304.1 - 9.1e-86 287.9 0.0 3.1e-85 286.2 0.0 1.7 2 0 0 2 2 2 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KLO13304.1 - 1.2e-24 86.3 0.0 2.3e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Methyltransf_28 PF02636.17 KLO13305.1 - 0.23 11.1 0.0 5.2 6.6 0.0 2.2 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase_Tyr PF07714.17 KLO13306.1 - 8.9e-35 120.2 0.0 1.1e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO13306.1 - 9.5e-31 107.1 0.0 1.2e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO13306.1 - 0.00019 21.4 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO13306.1 - 0.0013 17.6 0.0 0.0018 17.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KLO13306.1 - 0.024 13.7 0.1 0.034 13.2 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Fructosamin_kin PF03881.14 KLO13306.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase MFS_1 PF07690.16 KLO13307.1 - 7.7e-38 130.3 34.2 7.7e-38 130.3 34.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO13307.1 - 3.1e-06 26.3 32.1 5.8e-06 25.4 4.2 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 KLO13307.1 - 3.1e-05 22.6 1.5 4.3e-05 22.1 1.5 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector TMEM51 PF15345.6 KLO13313.1 - 0.043 13.7 4.5 0.047 13.5 1.2 2.2 1 1 1 2 2 2 0 Transmembrane protein 51 MLANA PF14991.6 KLO13313.1 - 0.12 12.6 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein melan-A Phage_holin_2_3 PF16080.5 KLO13313.1 - 0.19 11.5 0.4 0.43 10.4 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DAP10 PF07213.11 KLO13315.1 - 0.019 14.9 0.4 0.042 13.8 0.4 1.5 1 0 0 1 1 1 0 DAP10 membrane protein Amnionless PF14828.6 KLO13315.1 - 0.033 13.0 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Amnionless CD34_antigen PF06365.12 KLO13315.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family HlyIII PF03006.20 KLO13316.1 - 1.2e-56 191.9 19.0 1.6e-56 191.6 19.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related TMEM18 PF14770.6 KLO13316.1 - 0.16 12.0 7.5 0.09 12.8 4.2 2.1 2 0 0 2 2 2 0 Transmembrane protein 18 LHC PF00556.20 KLO13317.1 - 0.43 10.8 0.2 0.43 10.8 0.2 2.7 4 0 0 4 4 4 0 Antenna complex alpha/beta subunit MFS_1 PF07690.16 KLO13319.1 - 1.1e-23 83.7 29.2 1.6e-20 73.4 5.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Abhydrolase_9_N PF15420.6 KLO13320.1 - 2 8.4 9.1 9 6.2 9.1 2.1 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus STE3 PF02076.15 KLO13321.1 - 3.1e-55 187.4 15.8 3.8e-55 187.2 15.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor GPR_Gpa2_C PF11970.8 KLO13321.1 - 1.7 8.7 6.1 0.35 11.0 1.0 2.3 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Pro_CA PF00484.19 KLO13323.1 - 1.8e-14 54.3 0.0 2.3e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase HSBP1 PF06825.12 KLO13324.1 - 0.00011 22.0 13.0 0.0014 18.5 3.8 3.4 1 1 3 4 4 4 2 Heat shock factor binding protein 1 Apolipoprotein PF01442.18 KLO13324.1 - 0.00017 21.5 9.4 0.00088 19.2 2.2 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain SHE3 PF17078.5 KLO13324.1 - 0.017 14.9 1.6 0.021 14.6 0.7 1.7 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Exonuc_VII_L PF02601.15 KLO13324.1 - 0.036 13.6 5.9 0.44 10.1 5.9 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit GAS PF13851.6 KLO13324.1 - 0.051 12.9 9.7 0.024 14.0 3.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ApoLp-III PF07464.11 KLO13324.1 - 0.056 13.5 1.3 0.12 12.5 1.3 1.6 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Laminin_II PF06009.12 KLO13324.1 - 0.08 13.0 2.7 0.098 12.7 1.1 2.1 2 0 0 2 2 2 0 Laminin Domain II ANTH PF07651.16 KLO13324.1 - 0.12 11.4 4.1 0.22 10.5 4.0 1.5 1 1 0 1 1 1 0 ANTH domain AT_hook PF02178.19 KLO13324.1 - 0.31 11.0 5.7 0.77 9.8 5.7 1.7 1 0 0 1 1 1 0 AT hook motif DUF4407 PF14362.6 KLO13324.1 - 0.49 9.7 1.9 0.77 9.0 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5344 PF17279.2 KLO13324.1 - 1.3 9.6 4.0 1.8 9.2 0.4 3.0 3 1 1 4 4 2 0 Family of unknown function (DUF5344) OmpH PF03938.14 KLO13324.1 - 2 8.7 9.8 0.14 12.5 1.1 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) THOC7 PF05615.13 KLO13324.1 - 3.3 8.0 11.0 8.3 6.7 4.2 2.5 2 0 0 2 2 2 0 Tho complex subunit 7 DUF883 PF05957.13 KLO13324.1 - 4.5 7.9 7.6 9.9 6.8 0.3 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Fib_alpha PF08702.10 KLO13324.1 - 4.6 7.4 7.6 1.7 8.8 1.8 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KLO13324.1 - 5.4 7.1 11.5 3.1 7.8 2.8 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Com_YlbF PF06133.11 KLO13324.1 - 5.7 7.6 9.7 13 6.5 1.3 2.8 1 1 2 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA Fzo_mitofusin PF04799.13 KLO13324.1 - 8.9 5.8 9.4 3.8 7.0 0.9 2.7 1 1 1 3 3 3 0 fzo-like conserved region zf-C3HC4_3 PF13920.6 KLO13325.1 - 2.1e-13 49.9 7.8 2.1e-13 49.9 7.8 2.5 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO13325.1 - 3e-10 39.8 6.6 3e-10 39.8 6.6 2.7 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KLO13325.1 - 2.3e-07 31.0 7.0 2.3e-07 31.0 7.0 2.5 2 0 0 2 2 2 1 Ring finger domain FYVE PF01363.21 KLO13325.1 - 4.1e-07 30.0 8.2 4.1e-07 30.0 8.2 2.7 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4 PF00097.25 KLO13325.1 - 2.6e-05 24.0 8.3 2.6e-05 24.0 8.3 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO13325.1 - 0.0014 18.5 7.9 0.0014 18.5 7.9 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO13325.1 - 0.0028 17.6 5.9 0.0028 17.6 5.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain TFIIF_alpha PF05793.12 KLO13325.1 - 0.0064 15.1 6.2 0.014 14.0 6.2 1.5 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-P11 PF03854.14 KLO13325.1 - 0.0073 16.0 3.8 0.0073 16.0 3.8 2.4 2 0 0 2 2 2 1 P-11 zinc finger FYVE_2 PF02318.16 KLO13325.1 - 0.0079 16.4 3.5 0.0079 16.4 3.5 3.4 3 1 1 4 4 2 1 FYVE-type zinc finger Jnk-SapK_ap_N PF09744.9 KLO13325.1 - 0.51 10.6 18.4 0.81 9.9 18.4 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 zf-UDP PF14569.6 KLO13325.1 - 0.55 10.4 13.0 0.12 12.6 2.8 3.1 2 1 0 2 2 2 0 Zinc-binding RING-finger zf-RING_9 PF13901.6 KLO13325.1 - 1.6 8.6 11.4 0.27 11.2 1.0 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon GBP_C PF02841.14 KLO13325.1 - 1.9 7.8 16.8 3.2 7.1 16.8 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain AP-5_subunit_s1 PF15001.6 KLO13325.1 - 8.4 6.3 8.1 5.2 7.0 6.0 1.7 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 MBA1 PF07961.11 KLO13326.1 - 0.001 18.2 0.0 0.0017 17.5 0.0 1.4 1 1 0 1 1 1 1 MBA1-like protein FMO-like PF00743.19 KLO13327.1 - 2.2e-34 118.8 0.0 1.6e-23 82.9 0.0 2.4 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KLO13327.1 - 1.3e-18 67.3 0.0 1.4e-14 54.1 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KLO13327.1 - 7.1e-12 45.2 0.0 8.3e-11 41.6 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KLO13327.1 - 2.5e-06 27.6 3.2 0.41 10.6 0.0 4.0 3 1 1 4 4 4 3 FAD-NAD(P)-binding K_oxygenase PF13434.6 KLO13327.1 - 4e-05 22.9 0.4 0.0013 18.0 0.0 2.6 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KLO13327.1 - 0.00069 19.8 0.0 0.0076 16.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KLO13327.1 - 0.0013 17.6 0.8 1.5 7.5 0.0 3.2 3 1 1 4 4 4 2 HI0933-like protein DAO PF01266.24 KLO13327.1 - 0.016 14.8 7.2 14 5.1 0.0 4.2 5 0 0 5 5 5 0 FAD dependent oxidoreductase Sec20 PF03908.13 KLO13328.1 - 8.3e-17 60.9 4.6 2.1e-16 59.6 1.9 2.4 2 0 0 2 2 2 1 Sec20 KxDL PF10241.9 KLO13328.1 - 0.075 13.3 0.3 0.075 13.3 0.3 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein I_LWEQ PF01608.17 KLO13328.1 - 0.17 12.1 4.3 0.09 13.0 2.0 1.7 1 1 1 2 2 2 0 I/LWEQ domain MRP-S31 PF15433.6 KLO13328.1 - 0.2 11.3 3.8 0.29 10.8 3.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Apq12 PF12716.7 KLO13328.1 - 0.33 10.9 6.5 0.69 9.9 6.5 1.5 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Baculo_11_kDa PF06143.11 KLO13328.1 - 0.55 9.9 4.2 1.6 8.3 4.2 1.8 1 1 0 1 1 1 0 Baculovirus 11 kDa family MR_MLE_C PF13378.6 KLO13329.1 - 8e-58 195.6 0.1 1.1e-57 195.2 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KLO13329.1 - 2.7e-24 85.6 0.0 4.9e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF3983 PF13137.6 KLO13329.1 - 0.079 12.8 2.4 2.3 8.1 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) RSN1_7TM PF02714.15 KLO13330.1 - 1.8e-84 283.3 22.3 1.8e-84 283.3 22.3 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KLO13330.1 - 4.6e-36 123.9 4.8 4.6e-36 123.9 4.8 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KLO13330.1 - 5.3e-28 98.4 0.3 3e-21 76.4 0.1 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KLO13330.1 - 5.7e-08 32.8 0.1 3.4e-06 27.1 0.1 2.5 1 1 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Anoctamin PF04547.12 KLO13330.1 - 0.0027 16.6 0.5 0.0027 16.6 0.5 2.8 3 1 1 4 4 4 1 Calcium-activated chloride channel Syntaxin-6_N PF09177.11 KLO13331.1 - 6.7e-26 90.7 11.4 1.1e-25 90.0 0.8 2.9 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KLO13331.1 - 3.5e-09 36.5 1.2 3.5e-09 36.5 1.2 2.6 3 0 0 3 3 2 1 SNARE domain Use1 PF09753.9 KLO13331.1 - 4.6e-05 23.3 1.1 6.1e-05 22.9 1.1 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4407 PF14362.6 KLO13331.1 - 0.00015 21.3 7.0 0.0043 16.5 7.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) DUF3584 PF12128.8 KLO13331.1 - 0.00033 18.3 6.3 0.00047 17.9 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.11 KLO13331.1 - 0.0016 18.3 8.6 0.15 11.9 0.1 3.0 2 1 1 3 3 3 2 Bacillus haemolytic enterotoxin (HBL) Uso1_p115_C PF04871.13 KLO13331.1 - 0.0055 17.1 11.5 0.23 11.8 0.2 2.7 2 1 1 3 3 3 2 Uso1 / p115 like vesicle tethering protein, C terminal region SKA1 PF07160.12 KLO13331.1 - 0.0071 16.2 3.0 1.3 8.8 1.6 2.4 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 1 Prominin PF05478.11 KLO13331.1 - 0.0079 14.2 2.7 0.022 12.7 0.6 2.1 2 0 0 2 2 2 1 Prominin FlaC_arch PF05377.11 KLO13331.1 - 0.011 16.1 8.3 34 4.9 0.8 5.0 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 KLO13331.1 - 0.015 14.2 10.4 0.087 11.7 0.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein FliJ PF02050.16 KLO13331.1 - 0.024 14.9 9.2 1.8 8.8 3.5 2.9 2 2 1 3 3 3 0 Flagellar FliJ protein Fusion_gly PF00523.18 KLO13331.1 - 0.048 11.9 4.0 0.019 13.2 1.2 1.7 2 1 1 3 3 3 0 Fusion glycoprotein F0 XhlA PF10779.9 KLO13331.1 - 0.087 13.0 6.2 6.8 7.0 1.6 3.5 2 2 2 4 4 4 0 Haemolysin XhlA FPP PF05911.11 KLO13331.1 - 0.12 10.6 10.7 0.067 11.4 4.8 2.0 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil Jnk-SapK_ap_N PF09744.9 KLO13331.1 - 0.13 12.5 15.7 0.31 11.2 1.5 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DLP_helical PF18709.1 KLO13331.1 - 0.18 11.0 3.1 0.77 8.9 0.1 2.2 2 0 0 2 2 2 0 Dynamin-like helical domain Laminin_II PF06009.12 KLO13331.1 - 0.25 11.3 6.2 3.9 7.5 0.4 2.3 2 0 0 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.12 KLO13331.1 - 0.28 11.2 16.5 0.3 11.1 0.8 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 KLO13331.1 - 0.44 11.2 12.6 3.6 8.3 1.8 3.9 2 2 2 4 4 4 0 SlyX CENP-H PF05837.12 KLO13331.1 - 0.45 10.9 9.2 0.95 9.9 1.1 2.6 2 2 0 2 2 2 0 Centromere protein H (CENP-H) DUF5082 PF16888.5 KLO13331.1 - 0.46 10.8 6.2 1.8 8.9 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) TMF_DNA_bd PF12329.8 KLO13331.1 - 0.47 10.5 9.8 4.6 7.3 1.5 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding FH2 PF02181.23 KLO13331.1 - 0.61 9.1 5.6 1.1 8.4 0.5 2.2 1 1 0 2 2 2 0 Formin Homology 2 Domain Streptin-Immun PF11083.8 KLO13331.1 - 1.1 9.7 5.2 3.4 8.1 0.2 2.9 2 1 1 3 3 3 0 Lantibiotic streptin immunity protein DUF1640 PF07798.11 KLO13331.1 - 1.1 9.2 13.0 0.42 10.6 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Fzo_mitofusin PF04799.13 KLO13331.1 - 1.2 8.7 8.4 3 7.4 0.5 3.0 2 1 1 3 3 3 0 fzo-like conserved region Snapin_Pallidin PF14712.6 KLO13331.1 - 1.3 9.5 9.0 2.4 8.6 2.8 2.8 2 2 0 2 2 2 0 Snapin/Pallidin KxDL PF10241.9 KLO13331.1 - 1.6 9.1 9.4 3.8 7.8 5.7 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein Syntaxin_2 PF14523.6 KLO13331.1 - 1.8 8.9 6.3 0.8 10.1 0.8 2.5 2 2 0 2 2 2 0 Syntaxin-like protein DUF745 PF05335.13 KLO13331.1 - 2.5 7.8 10.4 5.5 6.7 2.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Seryl_tRNA_N PF02403.22 KLO13331.1 - 3.7 7.8 8.2 4.5 7.6 0.3 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG17 PF04108.12 KLO13331.1 - 4.4 6.3 10.9 9.7 5.2 3.7 2.3 2 1 0 2 2 2 0 Autophagy protein Apg17 EMP24_GP25L PF01105.24 KLO13331.1 - 5.6 6.9 8.0 23 4.9 2.7 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD UPF0242 PF06785.11 KLO13331.1 - 5.8 7.0 11.8 2.7 8.1 6.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4200 PF13863.6 KLO13331.1 - 6.4 7.2 14.3 1.7 9.1 1.1 3.1 3 1 1 4 4 3 0 Domain of unknown function (DUF4200) CdvA PF18822.1 KLO13331.1 - 9.5 6.1 13.6 7.2 6.5 1.0 3.6 3 2 1 4 4 3 0 CdvA-like coiled-coil domain p450 PF00067.22 KLO13333.1 - 2.2e-56 191.5 0.0 3.1e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ESPR PF13018.6 KLO13333.1 - 0.034 13.9 1.7 0.079 12.8 0.2 2.3 2 0 0 2 2 2 0 Extended Signal Peptide of Type V secretion system ADH_N PF08240.12 KLO13334.1 - 4.5e-29 100.5 1.7 7.7e-29 99.8 1.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO13334.1 - 1.3e-26 93.1 0.5 2.2e-26 92.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO13334.1 - 7e-08 33.6 0.2 1.2e-07 32.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KLO13334.1 - 0.059 12.8 0.1 0.16 11.4 0.1 1.8 2 0 0 2 2 2 0 short chain dehydrogenase TTC5_OB PF16669.5 KLO13334.1 - 0.095 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain CBM_1 PF00734.18 KLO13335.1 - 3.8e-12 45.9 9.0 3.8e-12 45.9 9.0 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF4900 PF16241.5 KLO13335.1 - 0.028 14.7 0.3 0.067 13.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4900) ERCC3_RAD25_C PF16203.5 KLO13336.1 - 3.8e-122 406.2 0.0 8.1e-122 405.2 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KLO13336.1 - 4e-37 127.2 0.0 8.3e-37 126.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO13336.1 - 4.6e-16 59.3 0.6 7.6e-16 58.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KLO13336.1 - 2.9e-12 46.9 0.2 1e-11 45.1 0.2 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KLO13336.1 - 1.3e-08 34.0 0.1 1.8e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cas_Csm6 PF09659.10 KLO13336.1 - 0.2 10.4 2.3 5.8 5.6 0.0 2.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csm6) zf-MYND PF01753.18 KLO13337.1 - 8.8e-08 32.1 12.0 1.8e-07 31.1 12.0 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO13338.1 - 6.6e-09 35.7 13.1 1.2e-08 34.9 13.1 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO13339.1 - 2.6e-08 33.8 12.2 2.6e-08 33.8 12.2 1.7 2 0 0 2 2 2 1 MYND finger MFS_1 PF07690.16 KLO13341.1 - 1.2e-30 106.7 26.7 5.3e-30 104.5 25.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PCI PF01399.27 KLO13342.1 - 3e-21 75.9 0.2 1.3e-20 73.9 0.0 2.1 3 0 0 3 3 3 1 PCI domain Rpn3_C PF08375.11 KLO13342.1 - 6.7e-20 71.3 0.3 1.6e-19 70.1 0.3 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 KLO13342.1 - 0.00021 21.1 1.3 0.13 12.4 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KLO13342.1 - 0.5 10.7 6.7 9.6 6.6 1.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KLO13342.1 - 0.5 11.3 2.5 1.8 9.6 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KLO13342.1 - 1.2 9.9 10.9 2.1 9.1 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.7 KLO13343.1 - 1.6e-08 34.3 3.4 2.8e-08 33.5 0.5 2.8 3 0 0 3 3 3 1 F-box-like Sec23_trunk PF04811.15 KLO13344.1 - 2.1e-71 240.3 0.0 4.2e-71 239.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KLO13344.1 - 2.4e-24 85.1 0.1 5.2e-24 84.0 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KLO13344.1 - 1.5e-17 64.1 0.0 3.9e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KLO13344.1 - 2e-16 59.7 4.8 4.4e-16 58.6 4.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KLO13344.1 - 2.8e-07 30.4 0.0 5.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KLO13344.1 - 6.8e-05 22.2 0.3 0.00015 21.1 0.3 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain WW PF00397.26 KLO13344.1 - 8.1e-05 22.6 1.8 8.1e-05 22.6 1.8 1.8 2 0 0 2 2 2 1 WW domain MFS_1 PF07690.16 KLO13346.1 - 1.2e-20 73.8 62.5 3.3e-19 69.0 28.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2238 PF09997.9 KLO13346.1 - 0.044 13.6 0.2 0.21 11.3 0.2 2.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) PITH PF06201.13 KLO13347.1 - 3.8e-35 121.4 0.0 5e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 PITH domain Ribosomal_S5_C PF03719.15 KLO13348.1 - 1.3e-20 72.6 0.2 4.4e-20 70.9 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KLO13348.1 - 1.7e-17 63.1 0.1 4e-17 61.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Stn1 PF10451.9 KLO13349.1 - 0.00023 20.2 5.4 0.00063 18.8 0.4 3.4 4 0 0 4 4 4 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KLO13349.1 - 0.032 14.2 0.5 0.11 12.5 0.5 1.9 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain LIM PF00412.22 KLO13350.1 - 1.3e-20 73.3 21.3 1.4e-11 44.5 1.4 4.8 4 2 0 4 4 4 4 LIM domain MFS_1 PF07690.16 KLO13351.1 - 2.1e-37 128.9 50.5 3.2e-37 128.3 48.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Olduvai PF06758.13 KLO13351.1 - 0.092 13.0 1.7 0.17 12.2 1.0 1.9 1 1 0 1 1 1 0 Olduvai domain DUF3087 PF11286.8 KLO13351.1 - 2.8 7.4 4.1 1.4 8.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Coatomer_WDAD PF04053.14 KLO13353.1 - 1.8e-137 459.0 0.1 3.7e-137 458.0 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 KLO13353.1 - 8.4e-110 367.3 0.0 1.2e-109 366.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KLO13353.1 - 8.6e-44 146.7 11.5 1.4e-07 32.1 0.4 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO13353.1 - 1.4e-11 44.5 0.2 0.0021 18.3 0.0 5.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KLO13353.1 - 0.016 15.1 0.1 0.13 12.1 0.0 2.5 4 0 0 4 4 4 0 Region in Clathrin and VPS eIF2A PF08662.11 KLO13353.1 - 0.11 12.3 0.0 10 5.9 0.0 3.2 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A TPR_14 PF13428.6 KLO13353.1 - 0.36 11.8 4.8 6.2 7.9 0.6 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KLO13353.1 - 0.58 10.4 2.6 16 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KLO13354.1 - 2.7e-08 33.2 0.0 4.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO13354.1 - 2.7e-06 27.4 11.8 6.6e-06 26.2 11.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase_Tyr PF07714.17 KLO13355.1 - 2.4e-33 115.5 0.0 4.1e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO13355.1 - 3.3e-28 98.8 0.0 5.5e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO13355.1 - 0.022 14.7 0.2 0.087 12.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family KH_1 PF00013.29 KLO13355.1 - 0.04 13.7 0.1 0.079 12.8 0.1 1.5 1 0 0 1 1 1 0 KH domain Cortex-I_coil PF09304.10 KLO13355.1 - 0.056 13.7 0.4 0.12 12.6 0.4 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil Peroxin-13_N PF04088.13 KLO13357.1 - 0.022 15.1 0.4 0.022 15.1 0.4 1.8 2 0 0 2 2 2 0 Peroxin 13, N-terminal region RseC_MucC PF04246.12 KLO13357.1 - 0.12 12.3 5.7 1.6 8.7 3.2 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Cation_efflux PF01545.21 KLO13357.1 - 0.55 9.9 9.7 2.1 8.0 0.0 2.6 2 1 1 3 3 3 0 Cation efflux family DUF3040 PF11239.8 KLO13357.1 - 8.3 6.8 5.9 2.8 8.3 1.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3040) WW PF00397.26 KLO13358.1 - 0.021 14.9 0.2 0.046 13.8 0.2 1.6 1 0 0 1 1 1 0 WW domain OST3_OST6 PF04756.13 KLO13358.1 - 0.037 13.4 0.1 0.066 12.6 0.1 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF3995 PF13160.6 KLO13358.1 - 5.4 7.4 10.2 0.9 9.9 1.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) Prothymosin PF03247.14 KLO13359.1 - 0.027 14.9 20.1 0.049 14.1 20.1 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.10 KLO13359.1 - 0.038 14.4 16.9 0.038 14.4 16.9 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.11 KLO13359.1 - 0.076 11.1 9.0 0.08 11.0 9.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TRAP_alpha PF03896.16 KLO13359.1 - 0.11 11.6 4.1 0.13 11.5 4.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RXT2_N PF08595.11 KLO13359.1 - 0.13 12.3 6.3 0.15 12.1 6.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Tub_N PF16322.5 KLO13359.1 - 0.39 11.1 12.9 0.46 10.9 12.9 1.1 1 0 0 1 1 1 0 Tubby N-terminal GCIP PF13324.6 KLO13359.1 - 0.55 9.8 4.6 0.53 9.8 4.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 KLO13359.1 - 0.57 8.3 13.9 0.6 8.2 13.9 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 KLO13359.1 - 1.1 8.4 15.6 1.1 8.3 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 KLO13359.1 - 1.1 8.5 13.7 1.1 8.5 13.7 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 KLO13359.1 - 1.1 9.0 10.2 1.5 8.6 10.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 KLO13359.1 - 1.3 7.3 7.2 1.1 7.4 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KLO13359.1 - 1.3 8.2 16.5 1.4 8.1 16.5 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 KLO13359.1 - 1.6 8.0 7.7 1.9 7.8 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_3_Rpc31 PF11705.8 KLO13359.1 - 1.7 8.8 18.9 2.2 8.5 18.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 KLO13359.1 - 2.1 6.3 16.7 2.2 6.3 16.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KLO13359.1 - 2.3 7.5 14.2 2.4 7.5 14.2 1.1 1 0 0 1 1 1 0 SDA1 Astro_capsid_p PF12226.8 KLO13359.1 - 2.6 7.1 15.5 2.9 7.0 15.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PPP4R2 PF09184.11 KLO13359.1 - 3.7 7.0 16.6 4.3 6.8 16.6 1.1 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 KLO13359.1 - 4.3 7.0 16.9 5.1 6.8 16.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myc_N PF01056.18 KLO13359.1 - 9.1 6.1 11.1 11 5.8 11.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF2457 PF10446.9 KLO13361.1 - 0.017 14.3 6.7 0.022 13.9 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 KLO13361.1 - 2.6 7.3 10.6 3.1 7.0 10.6 1.1 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 KLO13361.1 - 2.9 7.0 9.1 3.8 6.6 9.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Cwf_Cwc_15 PF04889.12 KLO13361.1 - 3.7 7.2 12.8 4.8 6.8 12.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KLO13361.1 - 4.4 5.4 10.7 5.2 5.1 10.7 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KLO13363.1 - 0.28 10.6 8.6 0.3 10.5 8.6 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KLO13363.1 - 0.37 10.1 11.1 0.36 10.1 11.1 1.0 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KLO13363.1 - 0.4 8.9 5.7 0.38 9.0 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 KLO13363.1 - 0.53 9.9 5.8 0.68 9.6 5.8 1.2 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 KLO13363.1 - 1.8 6.7 12.5 1.8 6.7 12.5 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KLO13363.1 - 2.2 7.5 12.3 2.4 7.4 12.3 1.1 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 KLO13363.1 - 2.5 7.9 10.9 3 7.7 10.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 KLO13363.1 - 7.1 4.6 12.8 8.4 4.4 12.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi WW PF00397.26 KLO13366.1 - 0.00057 19.9 0.6 0.0064 16.6 0.1 2.4 2 0 0 2 2 2 1 WW domain PI_PP_I PF18363.1 KLO13366.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain Fascin PF06268.13 KLO13368.1 - 0.002 18.4 0.0 0.0094 16.2 0.0 1.9 2 0 0 2 2 2 1 Fascin domain Piwi PF02171.17 KLO13369.1 - 3.8e-81 272.6 0.0 5.2e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KLO13369.1 - 1.2e-22 81.0 0.0 2.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KLO13369.1 - 3.9e-19 68.1 0.3 1.1e-18 66.6 0.3 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KLO13369.1 - 8.8e-13 48.4 0.0 3.1e-12 46.6 0.0 2.1 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KLO13369.1 - 4e-12 46.1 0.0 7.7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 PAZ domain MiaE PF06175.11 KLO13369.1 - 0.022 14.4 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) p450 PF00067.22 KLO13370.1 - 1.5e-76 258.0 0.0 1.9e-76 257.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.11 KLO13370.1 - 0.045 13.5 0.1 0.075 12.7 0.1 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split DUF3684 PF12449.8 KLO13376.1 - 0 1165.1 0.0 0 1164.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) DUF3810 PF12725.7 KLO13376.1 - 0.29 10.4 2.2 10 5.3 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) p450 PF00067.22 KLO13377.1 - 1.4e-72 245.0 0.0 2.8e-72 243.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 SICA_C PF12879.7 KLO13377.1 - 0.14 12.2 0.8 0.49 10.4 0.8 1.9 1 1 0 1 1 1 0 SICA C-terminal inner membrane domain Amidase PF01425.21 KLO13378.1 - 6e-77 259.5 0.0 2.5e-76 257.5 0.0 1.7 1 1 0 1 1 1 1 Amidase p450 PF00067.22 KLO13379.1 - 3.2e-72 243.8 0.1 6.6e-72 242.7 0.1 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO13380.1 - 1.2e-74 251.7 0.1 3e-74 250.4 0.1 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO13381.1 - 1.1e-71 242.0 0.0 2.4e-71 240.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_C97 PF05903.14 KLO13382.1 - 9.9e-06 25.5 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain WPP PF13943.6 KLO13382.1 - 0.068 13.6 5.1 2.2 8.7 2.3 2.5 2 0 0 2 2 2 0 WPP domain LRAT PF04970.13 KLO13382.1 - 0.33 11.3 0.1 0.33 11.3 0.1 2.5 2 1 1 3 3 3 0 Lecithin retinol acyltransferase DnaJ PF00226.31 KLO13383.1 - 4.5e-21 74.8 0.1 9.3e-21 73.7 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain FA_desaturase PF00487.24 KLO13383.1 - 0.0037 17.1 0.1 0.0055 16.6 0.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Parathyroid PF01279.17 KLO13383.1 - 0.5 11.0 3.1 14 6.3 0.7 2.7 2 1 0 2 2 2 0 Parathyroid hormone family TGT PF01702.18 KLO13384.1 - 1.3e-31 110.1 0.0 3.1e-20 72.6 0.0 2.1 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase Amidase PF01425.21 KLO13386.1 - 6.7e-74 249.5 0.0 4.1e-71 240.3 0.0 2.0 1 1 0 1 1 1 1 Amidase Abhydrolase_6 PF12697.7 KLO13387.1 - 4.8e-05 24.1 0.1 5.8e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_25 PF13649.6 KLO13389.1 - 6.8e-08 33.1 0.1 5.2e-06 27.1 0.0 2.9 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO13389.1 - 8e-05 22.5 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO13389.1 - 0.0002 22.0 0.1 0.0018 18.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO13389.1 - 0.013 16.2 0.1 0.14 12.9 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 KLO13389.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ArAE_2_N PF10337.9 KLO13390.1 - 3.4e-64 217.6 3.5 8e-64 216.4 2.2 2.0 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KLO13390.1 - 5.2e-36 124.6 0.4 1.8e-34 119.6 0.3 2.3 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KLO13390.1 - 1.2e-07 31.9 17.1 1.2e-07 31.9 17.1 3.8 3 0 0 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 KLO13390.1 - 0.00023 19.9 0.7 0.00023 19.9 0.7 4.0 4 1 0 4 4 4 2 Fusaric acid resistance protein family UvrD_C PF13361.6 KLO13390.1 - 0.026 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ArAE_2_N PF10337.9 KLO13391.1 - 2.7e-67 227.9 0.2 4.6e-67 227.1 0.2 1.3 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KLO13391.1 - 9.7e-30 104.1 0.4 1.1e-26 94.1 0.7 3.0 2 1 0 2 2 2 2 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KLO13391.1 - 1.9e-09 37.7 12.7 1.9e-09 37.7 12.7 3.1 3 0 0 3 3 3 1 Fusaric acid resistance protein-like WD40 PF00400.32 KLO13392.1 - 1.1e-15 57.7 3.2 6.4e-05 23.6 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO13392.1 - 2.3e-07 31.0 0.0 5.9 7.3 0.0 4.9 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KLO13392.1 - 0.024 13.3 0.0 0.11 11.2 0.0 2.1 1 1 0 1 1 1 0 Nucleoporin Nup120/160 DUF3756 PF12581.8 KLO13392.1 - 0.039 13.8 0.1 0.14 12.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) Ge1_WD40 PF16529.5 KLO13392.1 - 0.21 10.5 0.1 11 4.8 0.0 2.7 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Acetyltransf_10 PF13673.7 KLO13393.1 - 1.7e-09 37.7 0.0 3.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO13393.1 - 7.3e-07 29.5 0.0 1.3e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO13393.1 - 0.0002 21.6 0.0 0.00038 20.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KLO13394.1 - 9.2e-07 28.9 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO13394.1 - 9.2e-06 26.0 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO13394.1 - 1e-05 25.8 0.0 1.9e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family PCDO_beta_N PF12391.8 KLO13394.1 - 0.015 14.9 0.5 0.038 13.6 0.5 1.6 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal DUF4978 PF16349.5 KLO13394.1 - 0.096 12.3 0.0 0.5 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4978) Hydrophobin PF01185.18 KLO13396.1 - 0.00023 21.7 0.0 0.00031 21.3 0.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Nucleo_P87 PF07267.11 KLO13396.1 - 2.9 6.6 5.8 3.6 6.3 5.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 F-box PF00646.33 KLO13397.1 - 0.012 15.4 1.1 0.03 14.2 1.1 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO13397.1 - 0.044 13.7 0.9 0.15 12.0 0.9 1.9 1 0 0 1 1 1 0 F-box-like Glyco_hydro_10 PF00331.20 KLO13398.1 - 5.9e-97 324.6 0.1 7.2e-97 324.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Aldo_ket_red PF00248.21 KLO13400.1 - 3.5e-48 164.3 0.0 6.5e-46 156.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DIOX_N PF14226.6 KLO13401.1 - 2.6e-28 99.2 0.0 4.2e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO13401.1 - 2.6e-19 69.6 0.0 4.4e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phage_holin_2_4 PF16082.5 KLO13402.1 - 0.049 13.4 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like SKN1 PF03935.15 KLO13405.1 - 6.4e-193 641.7 2.2 8e-193 641.4 2.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) ABC_membrane PF00664.23 KLO13407.1 - 7.4e-59 199.6 33.0 3.3e-33 115.5 14.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KLO13407.1 - 2.7e-51 173.7 0.0 3.1e-29 102.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KLO13407.1 - 5.7e-10 39.0 0.3 0.0028 17.1 0.0 4.0 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KLO13407.1 - 4.7e-08 33.1 1.4 0.0041 17.2 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KLO13407.1 - 9.3e-08 32.2 0.4 0.018 14.9 0.0 3.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KLO13407.1 - 1.1e-06 29.2 1.0 0.01 16.3 0.1 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KLO13407.1 - 4.6e-06 26.3 0.1 0.089 12.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KLO13407.1 - 2.3e-05 24.4 0.2 0.23 11.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KLO13407.1 - 2.6e-05 24.8 1.0 0.12 12.9 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.6 KLO13407.1 - 3.1e-05 24.3 0.2 0.26 11.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KLO13407.1 - 0.00033 20.7 3.6 0.089 12.8 0.1 2.8 3 0 0 3 3 3 2 Dynamin family FtsK_SpoIIIE PF01580.18 KLO13407.1 - 0.0035 16.7 0.2 2.8 7.2 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_30 PF13604.6 KLO13407.1 - 0.0057 16.4 1.5 0.8 9.4 0.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KLO13407.1 - 0.007 16.0 0.2 0.14 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KLO13407.1 - 0.007 15.7 1.3 1.3 8.3 0.2 2.5 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.22 KLO13407.1 - 0.0091 15.2 0.7 3.6 6.7 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain Roc PF08477.13 KLO13407.1 - 0.01 16.0 0.4 3.1 8.0 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KLO13407.1 - 0.011 15.7 1.8 0.92 9.4 0.1 2.5 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.9 KLO13407.1 - 0.018 14.0 0.8 4.1 6.2 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 KLO13407.1 - 0.023 14.8 1.9 0.8 9.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 KLO13407.1 - 0.027 14.2 1.0 5 6.7 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain TsaE PF02367.17 KLO13407.1 - 0.027 14.4 0.1 7.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KLO13407.1 - 0.041 13.0 1.1 1.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KLO13407.1 - 0.079 12.5 0.1 7.8 6.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 KLO13407.1 - 0.099 12.5 0.5 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.6 KLO13407.1 - 0.1 12.9 0.1 4.9 7.5 0.1 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 KLO13407.1 - 0.11 12.0 1.5 5.5 6.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KLO13407.1 - 0.11 13.0 0.1 28 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KLO13407.1 - 0.15 11.6 0.1 8.4 6.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 KLO13407.1 - 0.16 11.7 1.3 25 4.6 0.1 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KLO13407.1 - 0.18 12.2 0.0 20 5.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase DUF5476 PF17570.2 KLO13407.1 - 2.4 8.6 5.6 2.4 8.6 0.2 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5476) COesterase PF00135.28 KLO13408.1 - 1.2e-139 466.5 0.0 2.1e-75 254.6 0.0 2.4 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO13408.1 - 6e-08 32.8 6.8 0.0053 16.7 1.1 3.4 2 2 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KLO13408.1 - 0.00014 21.4 0.0 0.3 10.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KLO13408.1 - 0.013 14.3 0.0 1.6 7.5 0.0 3.4 4 0 0 4 4 4 0 Steryl acetyl hydrolase F-box-like PF12937.7 KLO13409.1 - 1e-08 34.9 1.8 3.3e-08 33.3 1.8 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO13410.1 - 3.5e-08 33.2 5.3 1.5e-07 31.1 5.3 2.2 1 1 0 1 1 1 1 F-box-like COesterase PF00135.28 KLO13411.1 - 2.6e-78 264.2 0.0 4.3e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO13411.1 - 9.6e-05 22.3 1.8 0.0018 18.2 1.8 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO13411.1 - 0.075 11.9 0.0 0.56 9.0 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase Cellulase PF00150.18 KLO13412.1 - 0.00037 20.0 0.6 0.0008 18.9 0.6 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Secretin_N_2 PF07655.13 KLO13412.1 - 2.7 8.6 17.7 1e+02 3.5 0.0 2.9 2 0 0 2 2 2 0 Secretin N-terminal domain Chorion_3 PF05387.11 KLO13412.1 - 3.1 7.4 11.6 21 4.6 0.1 2.3 2 0 0 2 2 2 0 Chorion family 3 F-box-like PF12937.7 KLO13413.1 - 5e-06 26.3 1.7 1.4e-05 24.8 1.7 1.9 1 0 0 1 1 1 1 F-box-like COesterase PF00135.28 KLO13414.1 - 2.3e-77 261.0 0.0 5.6e-77 259.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO13414.1 - 8.3e-06 25.8 1.5 4.2e-05 23.5 1.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold L51_S25_CI-B8 PF05047.16 KLO13414.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.18 KLO13415.1 - 1.3e-85 286.7 0.0 1.4e-85 286.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Macro PF01661.21 KLO13415.1 - 0.059 13.4 0.3 1.6 8.8 0.1 2.8 1 1 2 3 3 3 0 Macro domain CutC PF03932.14 KLO13415.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.5 1 1 0 1 1 1 0 CutC family COesterase PF00135.28 KLO13416.1 - 7.3e-78 262.7 0.0 8.2e-77 259.2 0.0 2.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO13416.1 - 0.001 19.0 0.6 0.15 11.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold RabGAP-TBC PF00566.18 KLO13417.1 - 1e-37 129.9 0.0 1.9e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNase_H PF00075.24 KLO13418.1 - 2.4e-34 118.6 0.0 7.1e-34 117.0 0.0 1.8 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.16 KLO13418.1 - 2.6e-18 66.0 5.2 4.4e-18 65.3 5.2 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF4482 PF14818.6 KLO13418.1 - 0.17 12.8 0.6 0.43 11.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Glyco_hyd_65N_2 PF14498.6 KLO13419.1 - 0.0035 17.2 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain zf-MYND PF01753.18 KLO13420.1 - 3e-08 33.6 14.6 4.9e-08 32.9 14.6 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO13420.1 - 0.018 15.1 5.8 0.038 14.1 5.8 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KLO13420.1 - 1.1 9.6 13.7 2.4 8.5 13.7 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KLO13421.1 - 3.2e-07 30.3 15.2 6.4e-07 29.4 15.2 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO13421.1 - 1.4 9.1 7.1 2.8 8.1 7.1 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KLO13421.1 - 7.5 6.9 18.9 3.9 7.9 15.2 2.3 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding APH PF01636.23 KLO13422.1 - 1.7e-21 77.2 0.0 4e-21 76.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KLO13422.1 - 0.0096 15.5 0.0 0.04 13.5 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KLO13422.1 - 0.22 10.3 0.0 1.7 7.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pro_isomerase PF00160.21 KLO13423.1 - 3.2e-45 154.2 0.0 3.6e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.22 KLO13424.1 - 8.2e-46 155.6 0.0 9.2e-46 155.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO13424.1 - 2.1e-16 60.2 0.0 2.9e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KLO13424.1 - 2e-06 27.8 0.0 0.0024 17.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 KLO13424.1 - 2.8e-05 23.6 0.0 3.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_25 PF13481.6 KLO13424.1 - 0.0033 17.0 0.4 0.017 14.7 0.4 1.9 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KLO13424.1 - 0.0048 16.5 0.0 0.021 14.4 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Septin PF00735.18 KLO13424.1 - 0.013 14.8 0.0 3 7.0 0.0 2.2 2 1 0 2 2 2 0 Septin MMR_HSR1 PF01926.23 KLO13424.1 - 0.018 15.1 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase p450 PF00067.22 KLO13425.1 - 1.9e-73 247.8 0.0 2.2e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO13426.1 - 7e-64 216.3 0.0 8.7e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO13427.1 - 1.1e-64 218.9 0.0 1.4e-64 218.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KLO13428.1 - 0.0077 16.3 13.5 0.013 15.6 13.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KLO13429.1 - 9.1e-70 235.7 0.0 1.1e-69 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO13430.1 - 2.4e-68 231.0 0.0 3e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO13431.1 - 1.2e-64 218.8 0.0 6.1e-50 170.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KLO13432.1 - 5.4e-69 233.1 0.0 6.9e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GPP34 PF05719.11 KLO13433.1 - 1.1e-61 208.4 0.6 1.4e-61 208.1 0.6 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Syntaxin-6_N PF09177.11 KLO13434.1 - 0.078 13.5 0.7 1.3 9.6 0.0 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal MCPsignal PF00015.21 KLO13435.1 - 0.0023 17.8 8.0 0.32 10.8 0.3 3.6 2 1 2 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain ApoLp-III PF07464.11 KLO13435.1 - 0.0025 17.9 2.1 0.35 11.0 0.2 2.8 2 1 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 KLO13435.1 - 0.0038 17.3 10.8 0.84 9.7 0.3 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 KLO13435.1 - 0.0051 15.7 1.3 0.0051 15.7 1.3 3.0 2 1 1 3 3 3 1 Spc7 kinetochore protein DUF2205 PF10224.9 KLO13435.1 - 0.0056 16.6 3.7 3.3 7.8 0.1 3.3 2 1 0 2 2 2 2 Short coiled-coil protein Plk4_PB2 PF18409.1 KLO13435.1 - 0.019 15.6 3.8 14 6.4 0.0 3.5 3 1 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 SesA PF17107.5 KLO13435.1 - 0.025 14.8 2.4 1.6 8.9 0.1 2.8 1 1 2 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NPV_P10 PF05531.12 KLO13435.1 - 0.03 14.8 1.6 3 8.4 0.0 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.6 KLO13435.1 - 0.033 14.5 0.4 0.033 14.5 0.4 3.1 3 1 0 3 3 3 0 Syntaxin-like protein THP2 PF09432.10 KLO13435.1 - 0.053 13.6 4.9 2.9 7.9 0.2 3.0 2 1 0 3 3 3 0 Tho complex subunit THP2 MIP-T3_C PF17749.1 KLO13435.1 - 0.068 13.1 8.4 0.62 10.0 0.1 3.3 3 1 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Fib_alpha PF08702.10 KLO13435.1 - 0.18 12.0 10.0 0.64 10.2 0.2 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family RhoGAP-FF1 PF16512.5 KLO13435.1 - 0.28 11.9 1.8 4.3 8.1 0.5 2.8 3 0 0 3 3 2 0 p190-A and -B Rho GAPs FF domain Apolipoprotein PF01442.18 KLO13435.1 - 0.32 10.9 8.9 0.26 11.1 2.7 3.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain APG6_N PF17675.1 KLO13435.1 - 0.46 11.0 14.3 5.4 7.5 7.4 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region GCN5L1 PF06320.13 KLO13435.1 - 0.47 10.6 0.0 0.47 10.6 0.0 3.4 3 2 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) OrfB_IS605 PF01385.19 KLO13435.1 - 0.48 10.7 0.0 0.48 10.7 0.0 2.4 3 0 0 3 3 2 0 Probable transposase DASH_Duo1 PF08651.10 KLO13435.1 - 0.53 10.1 4.0 0.46 10.3 0.2 2.8 3 1 1 4 4 4 0 DASH complex subunit Duo1 LMBR1 PF04791.16 KLO13435.1 - 0.86 8.4 6.6 0.095 11.6 1.7 1.7 1 1 1 2 2 2 0 LMBR1-like membrane protein DUF948 PF06103.11 KLO13435.1 - 1.2 9.4 2.8 23 5.3 0.1 3.6 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TipAS PF07739.13 KLO13435.1 - 1.3 9.5 7.9 4 8.0 2.7 3.5 1 1 3 4 4 4 0 TipAS antibiotic-recognition domain COG5 PF10392.9 KLO13435.1 - 1.4 9.1 7.1 9.3 6.4 0.3 3.3 3 1 0 3 3 3 0 Golgi transport complex subunit 5 Seryl_tRNA_N PF02403.22 KLO13435.1 - 2.7 8.3 14.2 0.71 10.1 0.2 3.7 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DASH_Dad2 PF08654.10 KLO13435.1 - 3.1 8.3 6.3 11 6.5 0.1 3.8 2 1 2 4 4 4 0 DASH complex subunit Dad2 FTA4 PF13093.6 KLO13435.1 - 3.6 7.4 9.9 34 4.3 0.1 3.1 2 1 1 3 3 3 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2570 PF10828.8 KLO13435.1 - 3.7 7.4 8.0 2.6 7.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) DUF4355 PF14265.6 KLO13435.1 - 5.5 7.2 10.4 1.7 8.9 6.3 2.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4355) Mis14 PF08641.12 KLO13435.1 - 6.5 7.1 12.9 6.3 7.1 1.2 3.3 3 0 0 3 3 3 0 Kinetochore protein Mis14 like Laminin_II PF06009.12 KLO13435.1 - 8.6 6.4 9.7 2.5 8.1 0.2 3.1 3 0 0 3 3 3 0 Laminin Domain II DUF2203 PF09969.9 KLO13435.1 - 9.1 7.0 9.1 30 5.3 0.2 3.3 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF4795 PF16043.5 KLO13436.1 - 0.021 14.5 2.3 0.19 11.3 0.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) CdvA PF18822.1 KLO13436.1 - 0.051 13.4 1.4 4.2 7.2 0.1 2.4 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Apolipoprotein PF01442.18 KLO13436.1 - 0.097 12.5 0.2 5.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Mis14 PF08641.12 KLO13436.1 - 0.12 12.7 1.2 0.85 9.9 0.5 2.3 2 0 0 2 2 2 0 Kinetochore protein Mis14 like GIT_CC PF16559.5 KLO13436.1 - 0.13 12.2 0.9 0.59 10.0 0.1 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Hormone_1 PF00103.20 KLO13436.1 - 0.35 10.6 1.8 7.8 6.2 0.2 2.2 2 0 0 2 2 2 0 Somatotropin hormone family Apolipoprotein PF01442.18 KLO13437.1 - 0.0016 18.4 8.6 0.0026 17.7 6.4 2.3 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 KLO13437.1 - 0.0021 18.2 9.4 0.0022 18.2 5.8 2.7 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family ISG65-75 PF11727.8 KLO13437.1 - 0.003 16.9 6.8 0.0054 16.0 6.8 1.4 1 0 0 1 1 1 1 Invariant surface glycoprotein Exonuc_VII_S PF02609.16 KLO13437.1 - 0.004 17.2 1.2 2.6 8.2 0.1 3.6 4 0 0 4 4 3 1 Exonuclease VII small subunit Baculo_PEP_C PF04513.12 KLO13437.1 - 0.0046 17.0 4.1 0.35 10.9 0.0 3.7 3 1 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 KLO13437.1 - 0.0074 16.9 1.4 0.1 13.2 0.4 2.8 2 1 0 2 2 2 1 SlyX DUF2408 PF10303.9 KLO13437.1 - 0.0086 16.6 4.2 0.067 13.8 1.6 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2408) Spc7 PF08317.11 KLO13437.1 - 0.014 14.2 1.2 0.014 14.2 1.2 2.5 3 1 0 3 3 1 0 Spc7 kinetochore protein DASH_Duo1 PF08651.10 KLO13437.1 - 0.017 14.9 0.8 0.24 11.2 0.3 2.9 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF2397 PF09660.10 KLO13437.1 - 0.021 13.8 0.2 0.083 11.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) YnfE PF17452.2 KLO13437.1 - 0.025 14.9 0.5 0.96 9.8 0.1 2.9 1 1 0 2 2 2 0 Uncharacterized YnfE-like Surfac_D-trimer PF09006.11 KLO13437.1 - 0.03 14.2 0.6 0.21 11.5 0.1 2.3 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation SOGA PF11365.8 KLO13437.1 - 0.038 15.1 3.8 19 6.4 0.0 2.8 2 0 0 2 2 2 0 Protein SOGA DUF724 PF05266.14 KLO13437.1 - 0.04 13.8 0.8 0.04 13.8 0.8 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF724) HSA PF07529.13 KLO13437.1 - 0.044 14.1 2.2 0.044 14.1 2.2 1.7 2 0 0 2 2 1 0 HSA MscS_porin PF12795.7 KLO13437.1 - 0.048 13.2 4.7 0.18 11.3 0.0 2.8 2 1 0 3 3 3 0 Mechanosensitive ion channel porin domain DUF5344 PF17279.2 KLO13437.1 - 0.056 14.0 5.7 18 6.0 0.0 4.1 2 1 2 5 5 5 0 Family of unknown function (DUF5344) ALIX_LYPXL_bnd PF13949.6 KLO13437.1 - 0.056 12.7 8.7 0.031 13.6 6.5 1.7 2 1 0 2 2 1 0 ALIX V-shaped domain binding to HIV DUF1664 PF07889.12 KLO13437.1 - 0.057 13.5 0.9 0.057 13.5 0.9 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 KLO13437.1 - 0.058 14.0 5.1 6.1 7.5 3.3 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Syntaxin PF00804.25 KLO13437.1 - 0.086 12.5 9.7 5.5 6.6 3.7 3.2 1 1 1 3 3 3 0 Syntaxin KxDL PF10241.9 KLO13437.1 - 0.091 13.0 8.9 3.2 8.1 0.0 3.8 2 1 2 4 4 3 0 Uncharacterized conserved protein LXG PF04740.12 KLO13437.1 - 0.12 12.1 5.0 1 9.0 4.9 2.6 1 1 0 1 1 1 0 LXG domain of WXG superfamily FliT PF05400.13 KLO13437.1 - 0.12 13.2 3.6 5.9 7.8 0.7 3.1 2 1 1 3 3 3 0 Flagellar protein FliT Vps51 PF08700.11 KLO13437.1 - 0.14 12.2 6.1 4.3 7.5 0.3 4.2 2 1 1 4 4 4 0 Vps51/Vps67 MCPsignal PF00015.21 KLO13437.1 - 0.25 11.1 9.1 0.27 11.0 6.8 2.2 2 1 1 3 3 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CorA PF01544.18 KLO13437.1 - 0.28 10.5 2.8 0.47 9.7 1.4 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein TMPIT PF07851.13 KLO13437.1 - 0.3 10.3 8.3 0.12 11.6 3.2 2.3 1 1 2 3 3 3 0 TMPIT-like protein DUF148 PF02520.17 KLO13437.1 - 0.32 11.1 0.1 0.32 11.1 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF148 DUF4407 PF14362.6 KLO13437.1 - 0.32 10.3 5.1 2.1 7.6 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 KLO13437.1 - 0.35 11.4 8.6 0.88 10.1 0.1 4.4 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein FH2 PF02181.23 KLO13437.1 - 0.44 9.6 9.2 10 5.1 0.0 2.6 2 1 0 2 2 2 0 Formin Homology 2 Domain RasGAP_C PF03836.15 KLO13437.1 - 0.45 10.7 5.7 0.68 10.1 2.6 2.6 1 1 1 2 2 2 0 RasGAP C-terminus DUF948 PF06103.11 KLO13437.1 - 0.52 10.6 6.5 0.72 10.2 0.1 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CENP-Q PF13094.6 KLO13437.1 - 0.55 10.4 7.5 0.64 10.2 0.3 2.9 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Prominin PF05478.11 KLO13437.1 - 0.59 8.0 7.5 3 5.7 7.3 2.0 1 1 0 1 1 1 0 Prominin FlaC_arch PF05377.11 KLO13437.1 - 0.61 10.5 12.6 0.78 10.2 0.2 4.7 5 1 0 5 5 4 0 Flagella accessory protein C (FlaC) ApoLp-III PF07464.11 KLO13437.1 - 0.66 10.1 11.6 0.18 11.9 0.3 2.7 2 1 1 3 3 2 0 Apolipophorin-III precursor (apoLp-III) Exonuc_VII_L PF02601.15 KLO13437.1 - 0.73 9.4 6.6 1 8.8 5.9 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 KLO13437.1 - 0.73 7.7 6.9 0.46 8.3 5.0 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4446 PF14584.6 KLO13437.1 - 0.8 9.7 3.8 1.3 9.0 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DUF5082 PF16888.5 KLO13437.1 - 1.4 9.2 11.4 0.09 13.1 0.8 3.5 4 2 0 4 4 3 0 Domain of unknown function (DUF5082) Prefoldin_2 PF01920.20 KLO13437.1 - 1.7 8.7 12.9 0.53 10.3 1.2 4.3 4 2 0 4 4 4 0 Prefoldin subunit Syntaxin-6_N PF09177.11 KLO13437.1 - 1.8 9.2 11.1 1.8 9.2 6.0 3.2 3 1 0 3 3 2 0 Syntaxin 6, N-terminal UPF0242 PF06785.11 KLO13437.1 - 1.8 8.6 10.4 92 3.1 10.9 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FliJ PF02050.16 KLO13437.1 - 3.5 7.9 9.5 1.2 9.4 0.8 3.6 3 1 1 4 4 4 0 Flagellar FliJ protein YtxH PF12732.7 KLO13437.1 - 3.9 8.1 5.3 77 3.9 5.3 2.8 1 1 0 1 1 1 0 YtxH-like protein Sec34 PF04136.15 KLO13437.1 - 4.2 7.3 8.5 4.3 7.2 0.3 3.3 2 1 2 4 4 4 0 Sec34-like family Mt_ATP-synt_D PF05873.12 KLO13437.1 - 4.5 7.1 7.1 23 4.8 7.1 2.1 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Med9 PF07544.13 KLO13437.1 - 5.1 7.2 9.2 0.69 10.0 0.6 3.2 3 1 1 4 4 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2205 PF10224.9 KLO13437.1 - 5.4 7.1 9.8 14 5.7 0.0 3.6 3 1 1 4 4 3 0 Short coiled-coil protein APG6_N PF17675.1 KLO13437.1 - 6.5 7.3 11.8 0.48 10.9 0.6 2.5 2 1 1 3 3 2 0 Apg6 coiled-coil region ALMT PF11744.8 KLO13437.1 - 8.5 5.1 8.9 1.8 7.3 5.5 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter Laminin_II PF06009.12 KLO13437.1 - 9.2 6.3 13.0 0.4 10.7 0.7 3.5 2 1 2 4 4 4 0 Laminin Domain II Sigma70_r3 PF04539.16 KLO13439.1 - 0.0061 16.6 0.1 0.016 15.3 0.1 1.7 1 0 0 1 1 1 1 Sigma-70 region 3 Fungal_trans_2 PF11951.8 KLO13439.1 - 0.053 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF2315 PF10231.9 KLO13439.1 - 0.06 13.4 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Apoptogenic protein 1 Laminin_II PF06009.12 KLO13439.1 - 0.12 12.3 2.5 0.21 11.6 0.4 2.3 3 0 0 3 3 3 0 Laminin Domain II DUF745 PF05335.13 KLO13439.1 - 0.14 11.9 0.4 3.1 7.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF745) ABC_tran_CTD PF16326.5 KLO13441.1 - 0.0014 18.8 0.2 0.9 9.8 0.0 3.2 3 0 0 3 3 3 1 ABC transporter C-terminal domain DUF5082 PF16888.5 KLO13441.1 - 0.013 15.8 0.5 3.5 7.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Vps5 PF09325.10 KLO13441.1 - 0.022 14.3 0.5 5 6.6 0.1 2.2 2 0 0 2 2 2 0 Vps5 C terminal like Apolipoprotein PF01442.18 KLO13441.1 - 0.026 14.4 0.1 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DNA_repr_REX1B PF14966.6 KLO13441.1 - 0.027 15.1 0.1 1.1 10.0 0.0 2.4 2 0 0 2 2 2 0 DNA repair REX1-B Syntaxin_2 PF14523.6 KLO13441.1 - 0.045 14.1 0.3 0.91 9.9 0.2 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Mating_N PF12731.7 KLO13441.1 - 0.066 13.3 1.0 0.82 9.8 0.0 2.5 3 0 0 3 3 3 0 Mating-type protein beta 1 HMMR_N PF15905.5 KLO13441.1 - 0.1 12.1 0.1 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Nuc_recep-AF1 PF11825.8 KLO13441.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 APP_E2 PF12925.7 KLO13442.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein DUF1129 PF06570.11 KLO13443.1 - 0.0068 15.9 0.4 1.1 8.7 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1129) GWT1 PF06423.12 KLO13443.1 - 0.046 13.8 2.5 1.3 9.1 2.5 2.3 1 1 0 1 1 1 0 GWT1 DUF4064 PF13273.6 KLO13443.1 - 0.084 13.2 7.8 1.2 9.5 4.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Catalase-rel PF06628.12 KLO13444.1 - 0.15 12.3 0.0 0.83 9.9 0.0 2.2 2 0 0 2 2 2 0 Catalase-related immune-responsive DUF2508 PF10704.9 KLO13445.1 - 3.2 8.0 6.1 6.8 6.9 0.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2508) Glycos_transf_N PF04413.16 KLO13448.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Cu-oxidase_2 PF07731.14 KLO13449.1 - 0.089 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Multicopper oxidase BPS1 PF05633.11 KLO13450.1 - 0.0018 17.3 2.4 0.066 12.2 0.8 2.1 1 1 1 2 2 2 1 Protein BYPASS1-related Apolipoprotein PF01442.18 KLO13450.1 - 0.015 15.2 2.8 0.038 13.9 2.8 1.6 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 KLO13450.1 - 0.016 15.3 1.4 0.043 13.9 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Prominin PF05478.11 KLO13450.1 - 0.021 12.8 1.9 0.026 12.5 1.9 1.2 1 0 0 1 1 1 0 Prominin Ax_dynein_light PF10211.9 KLO13450.1 - 0.021 14.8 7.6 0.035 14.1 6.9 1.7 1 1 1 2 2 2 0 Axonemal dynein light chain YPEB PF14620.6 KLO13450.1 - 0.026 13.9 1.9 0.038 13.3 1.9 1.2 1 0 0 1 1 1 0 YpeB sporulation Syntaxin-6_N PF09177.11 KLO13450.1 - 0.027 15.0 3.9 0.16 12.5 3.2 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.6 KLO13450.1 - 0.034 14.5 6.6 0.064 13.6 5.8 1.9 1 1 0 1 1 1 0 Syntaxin-like protein DUF5082 PF16888.5 KLO13450.1 - 0.043 14.1 0.2 0.043 14.1 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Fzo_mitofusin PF04799.13 KLO13450.1 - 0.053 13.1 2.6 1.6 8.2 0.1 3.2 1 1 1 3 3 3 0 fzo-like conserved region ZapB PF06005.12 KLO13450.1 - 0.063 13.7 10.3 0.15 12.5 0.1 2.8 2 1 1 3 3 2 0 Cell division protein ZapB TACC_C PF05010.14 KLO13450.1 - 0.069 12.9 6.6 0.14 11.9 6.6 1.5 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Serine_rich PF08824.10 KLO13450.1 - 0.073 13.1 0.5 0.17 11.9 0.5 1.7 1 0 0 1 1 1 0 Serine rich protein interaction domain Baculo_PEP_C PF04513.12 KLO13450.1 - 0.075 13.1 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 KLO13450.1 - 0.089 13.1 1.5 1.3 9.4 0.2 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MeaB PF03308.16 KLO13450.1 - 0.098 11.6 1.3 0.16 10.9 1.3 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FlaC_arch PF05377.11 KLO13450.1 - 0.18 12.2 1.4 1.5 9.2 0.1 2.8 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Carbpep_Y_N PF05388.11 KLO13450.1 - 0.35 11.4 2.7 0.76 10.3 0.9 2.4 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide V_ATPase_I PF01496.19 KLO13450.1 - 0.35 8.7 4.0 0.47 8.3 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Jnk-SapK_ap_N PF09744.9 KLO13450.1 - 0.39 10.9 10.7 2.6 8.2 10.3 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 KLO13450.1 - 0.42 10.8 3.8 1.1 9.4 0.0 2.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KLO13450.1 - 0.45 9.4 9.0 0.74 8.6 9.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ING PF12998.7 KLO13450.1 - 0.48 11.0 5.3 16 6.2 1.8 2.9 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding YabA PF06156.13 KLO13450.1 - 0.75 10.5 6.8 6.1 7.5 6.2 2.5 1 1 0 1 1 1 0 Initiation control protein YabA CENP-H PF05837.12 KLO13450.1 - 0.93 9.9 8.1 16 6.0 8.2 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DHR10 PF18595.1 KLO13450.1 - 1.8 8.6 12.9 81 3.3 13.1 2.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain APG6_N PF17675.1 KLO13450.1 - 4.1 7.9 11.0 19 5.8 0.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 KLO13450.1 - 4.6 6.4 5.5 12 5.1 5.5 1.7 1 1 0 1 1 1 0 TMPIT-like protein FAM76 PF16046.5 KLO13450.1 - 8.5 5.6 10.2 0.47 9.7 0.2 2.1 1 1 1 2 2 2 0 FAM76 protein EspB_PE PF18625.1 KLO13452.1 - 0.037 14.5 0.3 1.2 9.7 0.0 2.9 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain NPV_P10 PF05531.12 KLO13452.1 - 0.091 13.2 1.6 9.8 6.7 0.1 3.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KLO13452.1 - 0.16 12.4 1.9 41 4.7 0.0 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.13 KLO13452.1 - 0.29 10.6 3.3 2 7.9 0.2 2.8 3 0 0 3 3 3 0 fzo-like conserved region DUF1319 PF07028.11 KLO13452.1 - 0.3 11.3 2.4 12 6.2 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1319) TMF_TATA_bd PF12325.8 KLO13452.1 - 2.2 8.5 7.3 6.5 7.0 0.5 3.2 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Ald_deCOase PF11266.8 KLO13454.1 - 0.041 13.6 0.0 0.63 9.7 0.0 2.1 1 1 1 2 2 2 0 Long-chain fatty aldehyde decarbonylase EAP30 PF04157.16 KLO13454.1 - 0.043 13.1 0.2 0.043 13.1 0.2 1.7 2 0 0 2 2 2 0 EAP30/Vps36 family DUF2009 PF09418.10 KLO13455.1 - 0.0048 16.0 1.7 0.0057 15.8 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) betaPIX_CC PF16523.5 KLO13455.1 - 0.0073 16.1 8.5 0.66 9.8 4.5 2.7 1 1 1 2 2 2 2 betaPIX coiled coil Cache_3-Cache_2 PF17201.4 KLO13455.1 - 0.022 14.0 0.6 0.029 13.6 0.6 1.2 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain DegQ PF08181.11 KLO13455.1 - 0.043 13.9 0.2 0.16 12.1 0.2 2.0 1 0 0 1 1 1 0 DegQ (SacQ) family TSC22 PF01166.18 KLO13455.1 - 0.071 13.4 3.1 1.9 8.9 0.2 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family Paralemmin PF03285.15 KLO13455.1 - 0.093 12.3 3.9 0.17 11.4 3.9 1.4 1 0 0 1 1 1 0 Paralemmin CREPT PF16566.5 KLO13455.1 - 0.099 12.8 6.2 3.8 7.7 0.3 3.1 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Flagellin_N PF00669.20 KLO13455.1 - 0.11 12.5 1.7 5.6 7.1 0.0 2.9 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region RNase_HII PF01351.18 KLO13455.1 - 0.13 12.1 2.8 0.25 11.1 2.8 1.4 1 0 0 1 1 1 0 Ribonuclease HII Syntaxin-6_N PF09177.11 KLO13455.1 - 0.14 12.8 6.3 0.65 10.6 3.7 2.7 2 1 2 4 4 4 0 Syntaxin 6, N-terminal ABC_tran_CTD PF16326.5 KLO13455.1 - 0.24 11.7 6.1 0.55 10.5 0.9 3.2 3 1 0 3 3 3 0 ABC transporter C-terminal domain PhaP_Bmeg PF09602.10 KLO13455.1 - 0.27 11.2 7.8 0.66 9.9 7.8 1.6 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) AvrM-A PF18241.1 KLO13455.1 - 0.28 11.6 8.7 0.13 12.7 6.0 1.8 2 0 0 2 2 2 0 Flax-rust effector AvrM-A LMBR1 PF04791.16 KLO13455.1 - 0.45 9.4 3.4 0.59 9.0 3.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4140 PF13600.6 KLO13455.1 - 0.49 10.9 0.1 0.49 10.9 0.1 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF2408 PF10303.9 KLO13455.1 - 0.62 10.6 8.4 1.1 9.8 7.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) FapA PF03961.13 KLO13455.1 - 1.1 7.8 8.5 0.83 8.2 5.4 1.9 1 1 0 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 KLO13456.1 - 0.0072 16.4 6.0 7.7 6.6 0.0 3.7 2 1 2 4 4 4 2 Protein of unknown function (DUF1664) COG2 PF06148.11 KLO13456.1 - 0.011 15.8 5.2 0.18 11.9 1.9 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3843 PF12954.7 KLO13456.1 - 0.013 14.5 0.1 0.02 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) FlaC_arch PF05377.11 KLO13456.1 - 0.17 12.3 4.7 4.7 7.7 0.0 3.8 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 KLO13456.1 - 0.59 9.3 3.8 7.9 5.6 0.2 2.4 2 1 1 3 3 3 0 TMPIT-like protein Dabb PF07876.12 KLO13456.1 - 0.64 10.7 2.8 2.8 8.6 0.1 3.0 3 1 1 4 4 4 0 Stress responsive A/B Barrel Domain PIN_8 PF18476.1 KLO13456.1 - 0.68 9.7 8.1 0.75 9.6 4.8 2.0 1 1 0 2 2 2 0 PIN like domain Fez1 PF06818.15 KLO13456.1 - 1.2 9.5 10.0 1 9.8 1.7 2.6 1 1 1 2 2 2 0 Fez1 DUF3713 PF12506.8 KLO13456.1 - 4.9 7.5 7.3 5.5 7.3 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3713) DUF4858 PF16150.5 KLO13457.1 - 0.013 15.6 0.0 0.015 15.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4858) Phytoreo_Pns PF05451.11 KLO13459.1 - 0.025 13.7 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 DUF2670 PF10875.8 KLO13460.1 - 0.03 14.4 0.0 0.11 12.6 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2670) LXG PF04740.12 KLO13460.1 - 0.038 13.7 1.8 0.72 9.5 0.1 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily FUSC PF04632.12 KLO13460.1 - 0.27 9.7 0.0 0.38 9.2 0.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Muted PF14942.6 KLO13461.1 - 0.00012 22.5 4.8 0.0021 18.4 3.6 2.5 3 0 0 3 3 2 1 Organelle biogenesis, Muted-like protein FapA PF03961.13 KLO13461.1 - 0.00019 20.2 3.3 0.00031 19.5 3.3 1.3 1 0 0 1 1 1 1 Flagellar Assembly Protein A Ax_dynein_light PF10211.9 KLO13461.1 - 0.00042 20.3 7.9 0.00098 19.1 7.9 1.6 1 0 0 1 1 1 1 Axonemal dynein light chain PTH2 PF01981.16 KLO13461.1 - 0.0028 17.9 1.1 2.7 8.3 0.7 2.4 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase PTH2 PHM7_cyt PF14703.6 KLO13461.1 - 0.0032 17.7 3.5 0.029 14.6 2.3 2.3 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter AAR2 PF05282.11 KLO13461.1 - 0.0045 16.5 0.9 0.0054 16.2 0.9 1.1 1 0 0 1 1 1 1 AAR2 protein Nbl1_Borealin_N PF10444.9 KLO13461.1 - 0.011 15.4 0.6 1.5 8.5 1.4 2.9 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Fzo_mitofusin PF04799.13 KLO13461.1 - 0.015 14.9 2.0 0.015 14.9 2.0 1.8 2 0 0 2 2 1 0 fzo-like conserved region DUF1729 PF08354.10 KLO13461.1 - 0.036 13.0 0.4 0.058 12.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Tnp_22_trimer PF17489.2 KLO13461.1 - 0.038 13.9 1.8 0.082 12.9 1.8 1.6 1 0 0 1 1 1 0 L1 transposable element trimerization domain Cytochrome_C554 PF13435.6 KLO13461.1 - 0.062 14.2 1.2 0.21 12.5 0.8 2.0 2 0 0 2 2 2 0 Cytochrome c554 and c-prime DUF3701 PF12482.8 KLO13461.1 - 0.08 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Phage integrase protein Syntaxin-6_N PF09177.11 KLO13461.1 - 0.091 13.3 5.3 0.11 13.1 2.3 2.6 2 1 2 4 4 3 0 Syntaxin 6, N-terminal WGR PF05406.15 KLO13461.1 - 0.091 12.8 0.5 0.31 11.1 0.1 2.0 1 1 1 2 2 2 0 WGR domain PRKG1_interact PF15898.5 KLO13461.1 - 0.1 13.5 7.3 0.33 11.9 7.3 1.8 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 KLO13461.1 - 0.15 12.7 6.5 0.45 11.2 6.5 1.8 1 0 0 1 1 1 0 Initiation control protein YabA Snf7 PF03357.21 KLO13461.1 - 0.19 11.3 8.3 0.38 10.3 7.6 1.9 2 0 0 2 2 2 0 Snf7 Syntaxin_2 PF14523.6 KLO13461.1 - 0.19 12.1 7.3 0.27 11.6 4.8 2.3 1 1 0 2 2 2 0 Syntaxin-like protein TMPIT PF07851.13 KLO13461.1 - 0.29 10.3 3.3 0.42 9.8 3.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 KLO13461.1 - 0.31 8.9 2.9 0.42 8.5 2.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.22 KLO13461.1 - 0.51 10.6 9.6 4.1 7.7 8.6 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KLO13461.1 - 0.55 10.3 5.7 0.22 11.5 2.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KLO13461.1 - 0.86 10.0 4.4 0.92 10.0 1.9 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 KLO13461.1 - 0.87 9.7 6.2 0.97 9.5 2.5 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 S6OS1 PF15676.5 KLO13461.1 - 0.94 7.9 9.9 1.8 6.9 9.8 1.4 1 1 0 1 1 1 0 Six6 opposite strand transcript 1 family DUF1192 PF06698.11 KLO13461.1 - 1.5 9.0 7.3 0.3 11.2 2.9 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF1192) Atg14 PF10186.9 KLO13461.1 - 1.8 7.5 13.0 3.3 6.7 12.5 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CCDC-167 PF15188.6 KLO13461.1 - 3.7 8.0 11.4 1.6 9.1 6.8 2.5 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 167 ZapB PF06005.12 KLO13461.1 - 4.1 7.9 10.5 37 4.9 10.5 2.5 1 1 0 1 1 1 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 KLO13461.1 - 6.3 6.3 9.9 17 4.9 9.9 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit FemAB PF02388.16 KLO13461.1 - 8.2 5.2 8.8 13 4.5 8.8 1.2 1 0 0 1 1 1 0 FemAB family ABC_tran_CTD PF16326.5 KLO13461.1 - 8.8 6.7 13.2 11 6.4 9.1 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain HBD PF18534.1 KLO13462.1 - 0.033 14.3 0.2 0.062 13.4 0.2 1.4 1 0 0 1 1 1 0 Helical bundle domain MIF4G_like_2 PF09090.11 KLO13463.1 - 0.0083 15.6 1.3 0.017 14.6 1.2 1.5 1 1 0 1 1 1 1 MIF4G like DUF4618 PF15397.6 KLO13463.1 - 0.0098 15.3 1.4 0.22 10.9 1.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) Mis12 PF05859.12 KLO13463.1 - 0.014 15.4 0.9 0.13 12.3 0.4 2.3 2 1 0 2 2 2 0 Mis12 protein TssO PF17561.2 KLO13463.1 - 0.018 15.2 0.1 3.1 7.9 0.0 2.2 1 1 1 2 2 2 0 Type VI secretion system, TssO GCIP PF13324.6 KLO13463.1 - 0.021 14.4 0.2 0.033 13.8 0.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Fib_alpha PF08702.10 KLO13463.1 - 0.033 14.4 1.7 0.56 10.4 0.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.8 KLO13463.1 - 0.17 12.0 0.8 6.6 6.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) NPV_P10 PF05531.12 KLO13463.1 - 0.99 9.9 4.8 2.1 8.8 0.1 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Cep57_MT_bd PF06657.13 KLO13464.1 - 0.0053 17.2 1.8 0.096 13.1 2.5 2.6 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 KLO13464.1 - 0.015 14.7 1.3 0.024 14.0 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DegQ PF08181.11 KLO13464.1 - 0.053 13.6 1.5 0.072 13.2 0.2 1.9 2 0 0 2 2 2 0 DegQ (SacQ) family OmpH PF03938.14 KLO13464.1 - 0.14 12.5 7.8 0.21 11.9 6.1 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.11 KLO13464.1 - 0.23 12.0 9.9 0.27 11.8 4.2 3.2 2 1 1 4 4 4 0 Syntaxin 6, N-terminal NAP PF00956.18 KLO13464.1 - 0.29 10.3 6.1 0.64 9.1 6.1 1.8 1 1 0 1 1 1 0 Nucleosome assembly protein (NAP) Nmad5 PF18757.1 KLO13464.1 - 0.37 11.0 5.8 0.49 10.6 0.0 2.6 2 1 0 2 2 2 0 Nucleotide modification associated domain 5 ABC_tran_CTD PF16326.5 KLO13464.1 - 0.59 10.4 6.2 0.3 11.3 1.3 3.0 3 1 0 4 4 4 0 ABC transporter C-terminal domain Uso1_p115_C PF04871.13 KLO13464.1 - 1.3 9.4 11.5 0.47 10.8 8.3 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMPIT PF07851.13 KLO13464.1 - 9.3 5.4 8.7 1.7 7.9 3.1 2.3 2 1 1 3 3 3 0 TMPIT-like protein TPR_2 PF07719.17 KLO13466.1 - 1.9e-27 93.1 3.2 0.0021 18.1 0.0 9.4 10 0 0 10 10 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO13466.1 - 5.5e-23 81.0 1.4 5.7e-10 39.3 0.1 5.9 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KLO13466.1 - 1.1e-22 78.9 0.0 2.4e-06 27.1 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KLO13466.1 - 2.4e-19 69.4 4.9 9.9e-09 35.4 0.0 7.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KLO13466.1 - 8.5e-19 66.1 0.1 0.0038 17.3 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KLO13466.1 - 4.5e-13 49.5 0.4 0.017 15.6 0.1 5.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KLO13466.1 - 4.8e-12 46.3 0.4 0.036 14.7 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KLO13466.1 - 7.5e-11 41.3 2.7 0.66 10.1 0.0 6.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KLO13466.1 - 4e-08 32.8 0.0 0.25 11.0 0.0 5.9 6 1 1 7 7 7 3 TPR repeat TPR_17 PF13431.6 KLO13466.1 - 8.7e-08 32.0 0.1 0.0053 17.1 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 KLO13466.1 - 1.3e-07 31.8 4.5 24 6.1 0.1 7.7 6 3 2 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 KLO13466.1 - 3e-06 26.9 0.1 0.42 10.6 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO13466.1 - 0.00033 20.1 0.6 0.023 14.1 0.0 3.1 4 0 0 4 4 4 1 MalT-like TPR region TPR_6 PF13174.6 KLO13466.1 - 0.0007 20.1 15.7 1.1 10.1 0.5 7.3 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KLO13466.1 - 0.057 13.6 3.3 6.3 7.0 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Ribosomal_S19e PF01090.19 KLO13466.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S19e PPR PF01535.20 KLO13466.1 - 0.2 12.0 1.3 10 6.6 0.0 3.6 3 0 0 3 3 2 0 PPR repeat TPR_4 PF07721.14 KLO13466.1 - 0.52 11.1 7.8 0.33 11.7 1.2 4.2 6 0 0 6 6 3 0 Tetratricopeptide repeat TOM13 PF08219.11 KLO13468.1 - 1.1e-13 51.0 0.6 2.6e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 Outer membrane protein TOM13 DUF2310 PF10071.9 KLO13469.1 - 0.29 10.4 2.5 0.37 10.0 2.5 1.2 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) CxC5 PF18718.1 KLO13469.1 - 0.56 10.3 7.9 0.41 10.7 6.7 1.4 1 1 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases XLF PF09302.11 KLO13470.1 - 8.6e-10 39.1 0.0 1.8e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component FHA PF00498.26 KLO13471.1 - 1.8e-08 34.6 0.0 3.1e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain G-patch PF01585.23 KLO13471.1 - 5.4e-06 26.2 0.1 1.3e-05 25.0 0.1 1.7 1 1 0 1 1 1 1 G-patch domain Yop-YscD_cpl PF16697.5 KLO13471.1 - 0.009 16.3 0.0 0.028 14.7 0.0 1.8 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain adh_short PF00106.25 KLO13472.1 - 5.2e-88 293.6 17.5 5e-45 153.4 3.8 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KLO13472.1 - 1.6e-69 234.0 18.7 9e-36 123.6 4.7 2.9 3 1 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KLO13472.1 - 6.3e-30 103.3 0.0 1.3e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KLO13472.1 - 5e-28 98.2 11.6 3.2e-14 53.2 3.3 2.2 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KLO13472.1 - 0.00023 20.5 1.3 0.032 13.6 0.4 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MaoC_dehydrat_N PF13452.6 KLO13472.1 - 0.0017 18.5 0.0 0.0057 16.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.18 KLO13472.1 - 0.0093 15.9 12.0 0.17 11.7 2.3 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Phage_portal_2 PF05136.13 KLO13472.1 - 0.051 12.7 0.2 3.9 6.5 0.0 2.6 3 0 0 3 3 3 0 Phage portal protein, lambda family Ldh_1_N PF00056.23 KLO13472.1 - 0.55 10.3 8.9 4.6 7.3 1.4 2.5 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DHHA1 PF02272.19 KLO13472.1 - 0.73 10.2 6.4 0.099 13.1 0.5 2.6 3 0 0 3 3 2 0 DHHA1 domain PglL_A PF15864.5 KLO13472.1 - 2.8 7.8 7.3 15 5.5 1.0 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase DUF543 PF04418.12 KLO13472.1 - 5.8 7.0 7.4 20 5.3 0.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) TAP_C PF03943.13 KLO13473.1 - 2e-13 49.8 0.0 4e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.6 KLO13473.1 - 0.00027 20.5 0.1 0.00051 19.6 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.20 KLO13473.1 - 0.00074 20.1 0.0 0.0052 17.3 0.0 2.3 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 KLO13473.1 - 0.008 16.6 3.0 0.012 16.0 0.6 2.4 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) UBA_4 PF14555.6 KLO13473.1 - 0.027 14.3 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain LRR_8 PF13855.6 KLO13473.1 - 0.13 12.0 1.6 0.45 10.3 1.6 1.9 1 0 0 1 1 1 0 Leucine rich repeat E3_UbLigase_EDD PF11547.8 KLO13473.1 - 0.18 11.5 0.1 0.44 10.3 0.1 1.7 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD TPK_catalytic PF04263.16 KLO13474.1 - 1.6e-36 124.9 0.1 2.2e-36 124.5 0.1 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KLO13474.1 - 1.5e-19 69.5 0.8 3e-19 68.5 0.8 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Acyl-CoA_dh_1 PF00441.24 KLO13475.1 - 1.5e-32 112.9 0.2 2.1e-32 112.4 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KLO13475.1 - 9.3e-17 60.9 0.0 2.3e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KLO13475.1 - 1.3e-15 57.4 0.5 2.3e-15 56.5 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KLO13475.1 - 8e-14 52.3 0.0 2.4e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KLO13475.1 - 1.3e-07 31.9 0.0 2.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Tektin PF03148.14 KLO13477.1 - 0.018 13.8 6.2 0.14 10.9 1.0 2.3 2 0 0 2 2 2 0 Tektin family DUF4407 PF14362.6 KLO13477.1 - 0.033 13.5 1.2 0.053 12.9 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KLO13477.1 - 0.086 12.9 9.5 2 8.4 0.3 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 KLO13477.1 - 0.095 12.9 7.6 0.14 12.3 5.6 2.1 2 0 0 2 2 2 0 Tropomyosin like Fib_alpha PF08702.10 KLO13477.1 - 0.15 12.3 10.6 2.4 8.4 0.1 3.3 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family EMP24_GP25L PF01105.24 KLO13477.1 - 0.2 11.6 3.4 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD MCPsignal PF00015.21 KLO13477.1 - 0.23 11.3 9.6 2.9 7.7 1.1 3.1 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Cluap1 PF10234.9 KLO13477.1 - 0.39 10.1 5.8 1 8.7 5.6 1.7 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF3391 PF11871.8 KLO13477.1 - 0.42 11.1 5.6 0.48 11.0 3.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DivIC PF04977.15 KLO13477.1 - 0.45 10.3 5.8 1.5 8.6 0.2 2.9 2 0 0 2 2 2 0 Septum formation initiator FapA PF03961.13 KLO13477.1 - 0.51 8.9 5.7 0.2 10.2 3.2 1.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A Prefoldin_2 PF01920.20 KLO13477.1 - 2.3 8.2 9.7 2 8.4 0.1 3.0 3 0 0 3 3 3 0 Prefoldin subunit DUF3450 PF11932.8 KLO13477.1 - 2.4 7.4 9.6 2 7.6 1.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.11 KLO13477.1 - 2.7 8.6 13.5 1.6 9.4 0.5 3.7 2 2 2 5 5 5 0 Syntaxin 6, N-terminal DMPK_coil PF08826.10 KLO13477.1 - 4.7 7.4 11.1 7 6.9 2.9 3.4 4 0 0 4 4 3 0 DMPK coiled coil domain like Fzo_mitofusin PF04799.13 KLO13477.1 - 6.9 6.2 9.8 9.8 5.7 0.0 3.4 3 1 0 3 3 3 0 fzo-like conserved region Borrelia_REV PF03978.13 KLO13478.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein JAKMIP_CC3 PF16034.5 KLO13478.1 - 0.048 13.6 0.2 0.094 12.7 0.2 1.4 1 1 0 1 1 1 0 JAKMIP CC3 domain Dfp1_Him1_M PF08630.10 KLO13478.1 - 0.084 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Dfp1/Him1, central region SH3_1 PF00018.28 KLO13480.1 - 3e-16 58.8 0.1 5.2e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KLO13480.1 - 8.8e-11 41.5 0.1 1.6e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KLO13480.1 - 1.7e-10 40.4 0.0 2.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.25 KLO13481.1 - 1.1e-34 120.0 0.1 1.2e-34 119.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13481.1 - 1.3e-17 63.9 0.0 1.5e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO13481.1 - 1.2e-06 28.0 0.0 1.8e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KLO13481.1 - 0.00029 20.8 0.4 0.00034 20.6 0.4 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO13481.1 - 0.0012 17.7 0.0 0.0013 17.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KLO13481.1 - 0.09 12.4 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KLO13481.1 - 0.22 10.4 0.1 0.25 10.2 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain MaoC_dehydratas PF01575.19 KLO13482.1 - 5.1e-31 106.8 0.0 9.8e-31 105.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KLO13482.1 - 0.00012 22.2 0.0 0.081 13.1 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Na_Ca_ex PF01699.24 KLO13483.1 - 1.2e-36 126.0 27.9 5e-20 72.0 11.5 3.6 4 0 0 4 4 4 2 Sodium/calcium exchanger protein NMT_C PF02799.15 KLO13484.1 - 4.9e-78 261.4 0.0 7.8e-78 260.8 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KLO13484.1 - 2.7e-76 254.9 0.0 4.2e-76 254.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KLO13484.1 - 1.1e-06 28.7 0.0 8.5e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO13484.1 - 8.7e-05 22.7 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KLO13484.1 - 0.018 15.0 0.1 0.059 13.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO13484.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PTPRCAP PF15713.5 KLO13484.1 - 6.8 7.0 12.1 12 6.2 12.1 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Ribosomal_L3 PF00297.22 KLO13485.1 - 1.2e-23 83.7 4.6 1.2e-21 77.1 2.1 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 OGG_N PF07934.12 KLO13486.1 - 1.1e-28 99.8 0.0 1.7e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KLO13486.1 - 2.5e-13 50.4 0.0 1.1e-12 48.4 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KLO13486.1 - 9.5e-05 22.1 0.0 0.00023 20.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Utp21 PF04192.12 KLO13487.1 - 6.7e-63 212.3 0.0 1e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KLO13487.1 - 3.9e-22 78.1 5.1 0.00039 21.1 0.0 9.1 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO13487.1 - 7.6e-16 58.2 0.0 7.5e-05 23.0 0.0 6.1 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KLO13487.1 - 0.03 14.1 0.4 11 5.6 0.0 3.0 2 1 0 3 3 3 0 TUP1-like enhancer of split Cytochrom_D1 PF02239.16 KLO13487.1 - 0.11 11.0 0.0 0.81 8.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.11 KLO13487.1 - 0.15 11.9 0.0 17 5.2 0.0 3.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.16 KLO13488.1 - 1.7e-27 96.3 20.0 2e-23 82.9 11.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily SKN1 PF03935.15 KLO13490.1 - 3.6e-189 629.3 2.5 4.2e-189 629.1 2.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) CMD PF02627.20 KLO13491.1 - 2.4e-17 62.8 0.7 1.1e-16 60.6 0.2 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Cofilin_ADF PF00241.20 KLO13492.1 - 1.4e-12 47.5 0.0 1.7e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein EF-hand_1 PF00036.32 KLO13492.1 - 0.069 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 EF hand RMMBL PF07521.12 KLO13492.1 - 0.12 12.4 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Mannosyl_trans PF05007.13 KLO13493.1 - 2.8e-64 217.5 18.9 2.8e-63 214.2 18.9 2.1 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KLO13493.1 - 6.4e-17 61.7 8.0 6.4e-17 61.7 8.0 2.1 3 0 0 3 3 3 1 GPI transamidase subunit PIG-U DUF1045 PF06299.12 KLO13493.1 - 0.014 15.3 0.9 0.035 14.1 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) RabGAP-TBC PF00566.18 KLO13494.1 - 2.5e-42 145.0 3.4 2.7e-39 135.0 1.2 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 KLO13494.1 - 4.1e-07 29.6 0.1 0.00033 20.2 0.0 2.3 2 0 0 2 2 2 2 Rab-binding domain (RBD) Lung_7-TM_R PF06814.13 KLO13494.1 - 0.15 11.3 0.8 0.23 10.7 0.8 1.2 1 0 0 1 1 1 0 Lung seven transmembrane receptor Exo_endo_phos PF03372.23 KLO13495.1 - 2.7e-05 23.8 0.0 0.00014 21.5 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NAD_binding_2 PF03446.15 KLO13496.1 - 1.2e-35 123.1 0.0 1.6e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KLO13496.1 - 2.9e-26 92.1 0.0 5.5e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 KLO13496.1 - 4.4e-05 22.6 0.0 7.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 KLO13496.1 - 0.0046 17.5 0.0 0.035 14.7 0.0 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent FIST PF08495.10 KLO13496.1 - 0.015 15.4 0.6 2.8 7.9 0.2 2.2 1 1 1 2 2 2 0 FIST N domain GFO_IDH_MocA PF01408.22 KLO13496.1 - 0.062 14.1 0.0 0.29 12.0 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold CAAD PF14159.6 KLO13496.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Acetyltransf_1 PF00583.25 KLO13499.1 - 5.5e-10 39.5 0.0 1e-09 38.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KLO13499.1 - 9.1e-08 32.4 0.1 3.1e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO13499.1 - 1.6e-06 28.1 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KLO13499.1 - 0.00012 21.8 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO13499.1 - 0.00013 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KLO13499.1 - 0.00044 20.9 0.0 0.0006 20.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KLO13499.1 - 0.045 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.18 KLO13499.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family SLATT_fungal PF18142.1 KLO13500.1 - 3.7e-33 114.1 0.1 6.7e-33 113.2 0.1 1.5 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Zw10 PF06248.13 KLO13500.1 - 0.0091 14.6 0.1 0.012 14.2 0.1 1.2 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 DUF2207 PF09972.9 KLO13500.1 - 0.086 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SLATT_1 PF18181.1 KLO13500.1 - 0.42 10.5 0.1 0.42 10.5 0.1 2.3 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Arf PF00025.21 KLO13501.1 - 1.2e-65 220.2 0.0 1.4e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KLO13501.1 - 3.7e-10 39.5 0.1 1.3e-06 27.9 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KLO13501.1 - 1.7e-08 34.1 0.0 2.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KLO13501.1 - 1.4e-07 31.7 0.0 3.4e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KLO13501.1 - 1.5e-07 31.5 0.0 2.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KLO13501.1 - 3.1e-07 30.1 0.0 3.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KLO13501.1 - 0.00019 20.9 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KLO13501.1 - 0.023 14.4 0.1 0.14 11.9 0.0 2.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 KLO13501.1 - 0.039 13.5 0.1 0.75 9.3 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KLO13502.1 - 1.6e-20 73.3 0.0 3.5e-20 72.2 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KLO13502.1 - 5.2e-13 48.8 0.0 8e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KLO13502.1 - 3.4e-08 33.1 0.0 5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KLO13502.1 - 3.8e-07 30.2 0.0 6.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KLO13502.1 - 1.1e-05 25.6 0.0 1.8e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KLO13502.1 - 0.00017 20.9 0.0 0.15 11.2 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Dynamin_N PF00350.23 KLO13502.1 - 0.00087 19.4 0.0 0.66 10.0 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Ras PF00071.22 KLO13502.1 - 0.0035 16.9 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 KLO13502.1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 KLO13502.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KLO13502.1 - 0.071 12.7 0.1 0.22 11.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain FixQ PF05545.11 KLO13502.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ SUI1 PF01253.22 KLO13503.1 - 7.7e-15 55.2 0.1 2.6e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 DUF2151 PF10221.9 KLO13503.1 - 0.9 8.1 5.1 1.3 7.5 5.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator PAP2 PF01569.21 KLO13504.1 - 7.5e-31 106.7 1.3 1.6e-30 105.6 1.3 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF2339 PF10101.9 KLO13504.1 - 0.0025 16.5 0.3 0.0044 15.7 0.3 1.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF5510 PF17629.2 KLO13504.1 - 0.15 12.0 0.1 0.41 10.6 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5510) PPP4R2 PF09184.11 KLO13505.1 - 1.9e-18 67.1 0.7 2.7e-18 66.6 0.0 1.6 2 0 0 2 2 2 1 PPP4R2 SNRNP27 PF08648.12 KLO13506.1 - 2.4e-28 97.9 1.2 4.4e-28 97.1 1.2 1.4 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins RRM_1 PF00076.22 KLO13507.1 - 0.0034 17.2 0.0 0.06 13.2 0.0 2.8 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KLO13508.1 - 6.6e-15 54.7 0.0 1.9e-14 53.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KLO13509.1 - 1.5e-05 25.7 0.7 0.22 12.5 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ PF01011.21 KLO13509.1 - 0.014 15.3 0.2 0.3 11.1 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat VID27 PF08553.10 KLO13509.1 - 0.048 12.7 0.0 0.094 11.7 0.0 1.4 1 1 0 1 1 1 0 VID27 C-terminal WD40-like domain ANAPC4_WD40 PF12894.7 KLO13509.1 - 0.12 12.7 0.1 9.7 6.6 0.0 2.9 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CASP_C PF08172.12 KLO13510.1 - 0.022 14.1 1.2 0.03 13.7 1.2 1.2 1 0 0 1 1 1 0 CASP C terminal DcpS_C PF11969.8 KLO13511.1 - 1.2e-15 58.0 0.3 2e-15 57.2 0.3 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KLO13511.1 - 9.8e-12 45.5 0.1 2.1e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 HIT domain zf-C2HE PF16278.5 KLO13511.1 - 8.7e-10 38.9 0.1 2.3e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger FYDLN_acid PF09538.10 KLO13511.1 - 0.014 16.1 1.3 0.014 16.1 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_4 PF13894.6 KLO13511.1 - 0.042 14.7 0.1 0.12 13.3 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Relaxase PF03432.14 KLO13511.1 - 0.59 9.7 10.1 5 6.7 9.5 2.5 1 1 0 1 1 1 0 Relaxase/Mobilisation nuclease domain PIG-Y PF15159.6 KLO13512.1 - 1e-19 71.2 6.0 1.3e-19 70.9 6.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y ADH_N PF08240.12 KLO13513.1 - 1.7e-29 101.9 0.5 3.2e-29 101.0 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO13513.1 - 4.9e-11 42.7 0.1 1.5e-10 41.2 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KLO13513.1 - 3.4e-06 26.7 0.0 3.2e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 KLO13513.1 - 0.00031 20.6 0.1 0.00088 19.2 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 KLO13513.1 - 0.00063 19.1 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KLO13513.1 - 0.00087 18.1 0.3 0.0029 16.4 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KLO13513.1 - 0.016 15.8 0.3 0.24 12.0 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KLO13513.1 - 0.018 15.3 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 KLO13513.1 - 0.022 14.0 0.2 0.32 10.2 0.1 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KLO13513.1 - 0.05 12.8 0.1 0.081 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N_2 PF13602.6 KLO13513.1 - 0.072 14.1 0.0 0.14 13.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ApbA PF02558.16 KLO13513.1 - 0.073 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 KLO13513.1 - 0.084 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KLO13513.1 - 0.088 12.7 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SUI1 PF01253.22 KLO13514.1 - 3.8e-25 88.2 0.5 4.9e-25 87.9 0.5 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 VASP_tetra PF08776.11 KLO13514.1 - 0.021 14.4 0.7 0.61 9.7 0.1 2.3 2 0 0 2 2 2 0 VASP tetramerisation domain rRNA_processing PF08524.11 KLO13515.1 - 0.44 10.5 23.1 0.059 13.4 14.9 2.8 2 1 0 2 2 2 0 rRNA processing RicinB_lectin_2 PF14200.6 KLO13521.1 - 1.3e-08 35.4 0.4 5.1e-06 27.1 0.1 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF3408 PF11888.8 KLO13522.1 - 1.2 9.2 4.4 0.36 11.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF2040 PF09745.9 KLO13523.1 - 7.7e-38 129.3 26.6 7.7e-38 129.3 26.6 2.7 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Pkinase PF00069.25 KLO13524.1 - 3.6e-07 29.8 0.0 1.7e-06 27.6 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain APH PF01636.23 KLO13524.1 - 0.0031 17.5 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KLO13524.1 - 0.013 14.9 0.0 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase TFIID-18kDa PF02269.16 KLO13525.1 - 3.1e-21 75.2 0.2 3.5e-21 75.0 0.2 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 KLO13525.1 - 0.03 14.6 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RRM_1 PF00076.22 KLO13526.1 - 6.8e-14 51.5 0.2 3e-12 46.2 0.2 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KLO13526.1 - 5.2e-09 36.1 0.0 7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 KLO13526.1 - 0.002 18.1 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KLO13526.1 - 0.13 12.5 0.1 2.7 8.2 0.0 2.1 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF2315 PF10231.9 KLO13527.1 - 6.9e-29 100.4 3.0 3.2e-28 98.3 3.0 1.9 1 1 0 1 1 1 1 Apoptogenic protein 1 DUF3974 PF13120.6 KLO13527.1 - 0.099 12.7 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) Nucleoporin_C PF03177.14 KLO13528.1 - 3.7e-80 270.3 0.5 4.5e-80 270.1 0.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KLO13528.1 - 2.6e-11 43.0 0.0 3.6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like NSP16 PF06460.12 KLO13528.1 - 0.051 12.7 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP16 AA_permease_2 PF13520.6 KLO13529.1 - 6.8e-64 216.3 42.1 8.4e-64 216.0 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KLO13529.1 - 1.8e-26 92.8 32.6 2.6e-26 92.3 32.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2705 PF10920.8 KLO13529.1 - 0.99 8.7 6.1 0.56 9.5 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2705) NAD_binding_6 PF08030.12 KLO13530.1 - 9.3e-19 68.1 0.0 3e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KLO13530.1 - 5.1e-18 65.4 10.7 5.1e-18 65.4 10.7 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KLO13530.1 - 7.9e-10 38.8 0.0 1.1e-05 25.5 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain Alpha-amylase PF00128.24 KLO13531.1 - 1.2e-22 81.0 0.3 2.3e-19 70.2 0.1 3.1 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KLO13531.1 - 1.3e-14 54.6 0.0 2.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KLO13531.1 - 4.7e-08 32.8 0.0 8.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KLO13531.1 - 3.6e-07 30.7 0.0 6.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase PF00069.25 KLO13533.1 - 6.2e-70 235.6 0.0 8.6e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13533.1 - 1.3e-45 155.7 0.0 2.1e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_2 PF07647.17 KLO13533.1 - 1.6e-10 41.0 0.0 3.7e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 KLO13533.1 - 4.5e-09 36.5 0.0 8.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 KLO13533.1 - 1.1e-08 35.3 0.0 2.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 KLO13533.1 - 7.6e-05 22.2 0.0 0.00094 18.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like SAM_4 PF18017.1 KLO13533.1 - 0.00037 20.4 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 KLO13533.1 - 0.071 11.9 0.0 0.18 10.5 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase TRM PF02005.16 KLO13534.1 - 2.2e-113 379.3 0.1 3.4e-87 293.1 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase FCP1_C PF09309.10 KLO13534.1 - 5.3 6.9 12.4 0.45 10.4 7.2 1.8 2 0 0 2 2 2 0 FCP1, C-terminal Histone PF00125.24 KLO13535.1 - 2.6e-23 82.8 1.5 3.4e-23 82.5 1.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KLO13535.1 - 2.3e-06 27.8 0.1 6.2e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KLO13535.1 - 0.00033 21.1 0.0 0.00052 20.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 KLO13535.1 - 0.0089 16.2 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 CENP-W protein YscO-like PF16789.5 KLO13535.1 - 0.032 14.3 0.2 0.038 14.0 0.2 1.1 1 0 0 1 1 1 0 YscO-like protein Bt_P21 PF05560.11 KLO13535.1 - 0.073 12.7 0.1 0.092 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein ox_reductase_C PF08635.10 KLO13536.1 - 6.8e-75 249.4 0.1 9.6e-75 249.0 0.1 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 KLO13536.1 - 8.5e-24 84.7 0.0 1.4e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KLO13536.1 - 0.0019 18.2 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain SKA2 PF16740.5 KLO13537.1 - 0.0025 17.6 1.6 0.0037 17.0 1.6 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Leu_zip PF15294.6 KLO13537.1 - 0.0037 16.8 3.1 0.0059 16.1 3.1 1.3 1 0 0 1 1 1 1 Leucine zipper DUF4510 PF14971.6 KLO13537.1 - 0.027 14.8 2.3 0.043 14.2 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) EMP24_GP25L PF01105.24 KLO13537.1 - 0.042 13.8 0.2 0.047 13.6 0.2 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD UPF0449 PF15136.6 KLO13537.1 - 0.081 13.4 3.2 0.14 12.6 2.5 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF16 PF01519.16 KLO13537.1 - 0.12 12.9 2.5 0.2 12.2 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF5340 PF17275.2 KLO13537.1 - 0.12 12.5 3.6 0.094 12.9 1.7 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5340) V_ATPase_I PF01496.19 KLO13537.1 - 0.21 9.5 2.7 0.25 9.2 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL6 PF01763.16 KLO13537.1 - 0.27 9.7 5.6 0.37 9.3 5.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF3810 PF12725.7 KLO13537.1 - 0.72 9.2 2.9 0.96 8.7 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) bZIP_Maf PF03131.17 KLO13537.1 - 0.88 10.1 11.4 0.089 13.3 6.1 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Cdh1_DBD_1 PF18196.1 KLO13537.1 - 0.96 9.8 6.0 0.36 11.2 2.3 1.9 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DUF4140 PF13600.6 KLO13537.1 - 1.4 9.4 6.9 0.2 12.1 2.9 1.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3987 PF13148.6 KLO13537.1 - 2 7.3 8.0 0.45 9.5 4.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) ZapB PF06005.12 KLO13537.1 - 6.3 7.3 13.4 0.7 10.4 8.8 1.8 2 0 0 2 2 2 0 Cell division protein ZapB RNase_PH PF01138.21 KLO13538.1 - 3.2e-32 111.8 0.1 4.6e-32 111.3 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KLO13538.1 - 0.003 17.6 0.1 0.0053 16.8 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 F-box-like PF12937.7 KLO13539.1 - 1.2e-06 28.3 1.7 1.2e-06 28.3 1.7 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO13539.1 - 4.3e-05 23.3 0.7 9.4e-05 22.2 0.7 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KLO13539.1 - 0.00037 20.4 0.1 0.00088 19.1 0.1 1.6 1 0 0 1 1 1 1 F-box Glyco_hydro_61 PF03443.14 KLO13540.1 - 1.4e-50 172.1 0.0 1.7e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Methyltransf_11 PF08241.12 KLO13541.1 - 1.9e-14 54.1 0.0 3.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO13541.1 - 3.9e-12 46.7 0.0 1.3e-11 45.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO13541.1 - 4.1e-10 39.7 0.0 5.5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO13541.1 - 4.1e-08 33.9 0.0 1.5e-07 32.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO13541.1 - 0.00063 19.6 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KLO13541.1 - 0.0021 17.4 0.0 0.0044 16.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 KLO13541.1 - 0.0038 16.3 0.0 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.17 KLO13541.1 - 0.099 12.3 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PRCC PF10253.9 KLO13543.1 - 8.6e-20 72.5 10.1 8.6e-20 72.5 10.1 3.3 2 2 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting DAGK_cat PF00781.24 KLO13544.1 - 1.1e-21 76.8 0.0 3.2e-21 75.2 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain SAP PF02037.27 KLO13545.1 - 4.2e-10 39.1 0.2 6.8e-10 38.5 0.2 1.4 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 KLO13545.1 - 0.096 12.6 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain LEP503 PF15221.6 KLO13546.1 - 0.2 12.0 0.8 0.4 11.1 0.2 1.8 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 PRIMA1 PF16101.5 KLO13547.1 - 1.8 8.6 5.0 3.6 7.6 5.0 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Methyltransf_11 PF08241.12 KLO13548.1 - 2.3e-12 47.4 0.0 5.3e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO13548.1 - 7.2e-09 36.2 0.0 1.5e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO13548.1 - 4.2e-06 26.7 0.0 6.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO13548.1 - 3.4e-05 24.5 0.0 6.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO13548.1 - 0.00024 20.5 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KLO13548.1 - 0.028 14.2 0.0 9.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KLO13549.1 - 3e-15 56.6 0.0 7.5e-15 55.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO13549.1 - 2.6e-12 47.3 0.0 9.8e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO13549.1 - 9.3e-09 35.3 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO13549.1 - 2.7e-08 34.5 0.0 1e-07 32.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO13549.1 - 8.6e-08 31.8 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KLO13549.1 - 0.00069 19.4 0.0 0.0015 18.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KLO13549.1 - 0.0044 18.0 0.0 0.011 16.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 KLO13549.1 - 0.0085 15.2 0.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 KLO13549.1 - 0.069 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CDC45 PF02724.14 KLO13550.1 - 1.1e-219 731.0 0.0 1.3e-219 730.7 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop53 PF07767.11 KLO13550.1 - 0.2 11.0 6.9 0.36 10.2 6.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Cofilin_ADF PF00241.20 KLO13551.1 - 2.5e-38 130.6 0.0 2.9e-18 65.8 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.32 KLO13552.1 - 0.021 15.7 3.7 6.6 7.8 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat zf-C2H2 PF00096.26 KLO13553.1 - 2.9e-06 27.4 3.4 0.011 16.2 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO13553.1 - 1.2e-05 25.7 3.2 0.0078 17.0 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KLO13553.1 - 0.00018 21.7 0.7 0.024 14.9 0.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KLO13553.1 - 0.0034 17.7 0.2 0.61 10.6 0.1 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KLO13553.1 - 0.1 12.6 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 KLO13553.1 - 0.12 12.7 1.5 0.41 10.9 1.5 2.0 1 0 0 1 1 1 0 zinc-ribbon zf-C2H2_11 PF16622.5 KLO13553.1 - 0.14 11.9 0.8 10 6.0 0.3 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type BRI3BP PF14965.6 KLO13554.1 - 0.012 15.1 0.2 0.028 13.9 0.2 1.5 1 0 0 1 1 1 0 Negative regulator of p53/TP53 UCR_6-4kD PF08997.10 KLO13554.1 - 0.1 12.5 0.7 18 5.4 0.2 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein DUF3272 PF11676.8 KLO13555.1 - 0.0042 17.3 2.2 0.66 10.3 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3272) DUF1689 PF07954.11 KLO13555.1 - 0.13 12.7 0.5 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) Glyco_hydro_30 PF02055.16 KLO13556.1 - 2.9e-23 82.4 0.5 4.1e-23 81.9 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KLO13556.1 - 1.7e-14 53.8 0.1 2.8e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Sod_Fe_C PF02777.18 KLO13557.1 - 9.2e-36 122.1 0.1 1.6e-35 121.4 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KLO13557.1 - 4.3e-32 110.4 3.5 4.3e-32 110.4 3.5 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AsmA_1 PF13109.6 KLO13557.1 - 0.034 13.6 0.0 0.25 10.8 0.0 2.0 1 1 1 2 2 2 0 AsmA-like C-terminal region G_glu_transpept PF01019.21 KLO13558.1 - 3e-145 484.9 0.0 3.4e-145 484.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase WD40 PF00400.32 KLO13559.1 - 9.6e-53 175.0 22.5 5.8e-12 45.9 0.2 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO13559.1 - 2.9e-22 78.8 2.0 0.0025 18.1 0.0 5.2 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO13559.1 - 1.2e-09 38.3 0.7 0.00068 19.6 0.0 3.2 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KLO13559.1 - 2.5e-09 36.8 0.3 1.6 8.8 0.0 5.7 6 0 0 6 6 5 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KLO13559.1 - 6.5e-08 31.9 0.2 1.2 8.1 0.0 4.9 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KLO13559.1 - 2.3e-07 30.6 2.4 0.96 9.4 0.0 5.2 5 0 0 5 5 5 2 Nitrous oxide reductase propeller repeat Nup160 PF11715.8 KLO13559.1 - 1.9e-05 23.5 2.8 0.076 11.6 0.1 3.8 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Ret2_MD PF18528.1 KLO13559.1 - 3e-05 24.3 0.0 7 7.1 0.0 4.4 1 1 4 5 5 5 1 RNA editing 3' terminal uridylyl transferase 2 middle domain Cytochrom_D1 PF02239.16 KLO13559.1 - 5.5e-05 21.9 3.5 0.0025 16.4 0.2 3.2 1 1 3 4 4 4 2 Cytochrome D1 heme domain MMS1_N PF10433.9 KLO13559.1 - 0.00019 20.2 0.0 1.1 7.8 0.0 3.1 1 1 2 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40_like PF17005.5 KLO13559.1 - 0.0002 20.8 0.0 2.4 7.4 0.0 3.6 3 2 0 3 3 3 2 WD40-like domain PQQ_3 PF13570.6 KLO13559.1 - 0.00038 20.9 8.6 1.6 9.3 0.1 4.8 4 1 1 5 5 5 1 PQQ-like domain Proteasome_A_N PF10584.9 KLO13559.1 - 0.00062 19.4 4.1 44 3.9 0.0 5.9 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Cuticle_4 PF15955.5 KLO13559.1 - 0.0012 19.5 0.4 34 5.2 0.0 4.1 3 1 0 4 4 4 0 Cuticle protein Nucleoporin_N PF08801.11 KLO13559.1 - 0.0031 16.3 2.5 2 7.1 0.4 4.1 1 1 1 2 2 2 2 Nup133 N terminal like DsbC_N PF10411.9 KLO13559.1 - 0.012 15.1 0.0 37 3.9 0.0 4.4 5 0 0 5 5 5 0 Disulfide bond isomerase protein N-terminus PQQ_2 PF13360.6 KLO13559.1 - 0.012 15.2 10.6 0.037 13.6 10.6 2.0 1 1 0 1 1 1 0 PQQ-like domain DUF5122 PF17164.4 KLO13559.1 - 0.02 15.2 3.0 1.6e+02 2.7 0.0 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller PQQ PF01011.21 KLO13559.1 - 0.045 13.7 1.3 65 3.7 0.0 4.6 4 1 0 4 4 4 0 PQQ enzyme repeat Cir_N PF10197.9 KLO13559.1 - 0.05 13.8 3.0 63 3.9 0.0 4.5 5 0 0 5 5 5 0 N-terminal domain of CBF1 interacting co-repressor CIR SdiA-regulated PF06977.11 KLO13559.1 - 0.09 12.0 0.0 3.8 6.7 0.0 2.4 1 1 1 2 2 2 0 SdiA-regulated NHL PF01436.21 KLO13559.1 - 0.11 12.6 6.2 7.9 6.7 0.1 4.6 5 0 0 5 5 5 0 NHL repeat NACHT PF05729.12 KLO13560.1 - 2e-06 27.8 0.3 4.7e-06 26.6 0.3 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO13560.1 - 8e-05 23.1 0.0 0.00022 21.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KLO13560.1 - 0.00052 20.5 0.1 0.0012 19.3 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO13560.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KLO13560.1 - 0.0075 16.0 0.1 0.026 14.2 0.0 1.9 1 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KLO13560.1 - 0.033 14.1 0.0 0.15 12.0 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea FANCI_S1 PF14675.6 KLO13560.1 - 0.051 13.1 0.0 0.063 12.8 0.0 1.1 1 0 0 1 1 1 0 FANCI solenoid 1 RNA_helicase PF00910.22 KLO13560.1 - 0.055 13.9 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase G_glu_transpept PF01019.21 KLO13562.1 - 5.9e-118 394.9 0.0 9.2e-83 278.7 0.0 2.0 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase WD40 PF00400.32 KLO13563.1 - 8.1e-19 67.6 11.3 4.9e-08 33.5 0.2 4.5 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO13563.1 - 4.9e-06 26.7 0.0 0.17 12.2 0.0 3.0 1 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KLO13563.1 - 0.00016 21.6 4.7 0.0019 18.1 4.7 2.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO13563.1 - 0.00024 21.5 0.1 0.00064 20.1 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KLO13563.1 - 0.0036 17.7 0.0 0.032 14.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PD40 PF07676.12 KLO13563.1 - 0.017 15.1 0.1 27 4.9 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat AAA_22 PF13401.6 KLO13563.1 - 0.14 12.4 0.0 0.48 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain PQQ_3 PF13570.6 KLO13563.1 - 0.18 12.4 2.9 9.8 6.8 0.1 3.5 3 0 0 3 3 3 0 PQQ-like domain OppC_N PF12911.7 KLO13564.1 - 3.7 7.6 7.9 62 3.7 0.0 3.3 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C TFIIA PF03153.13 KLO13564.1 - 5.1 7.0 8.9 7 6.5 8.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box-like PF12937.7 KLO13566.1 - 2.7e-07 30.3 0.0 7.7e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like COG6 PF06419.11 KLO13566.1 - 0.069 11.4 0.1 0.13 10.5 0.1 1.3 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 BTB PF00651.31 KLO13570.1 - 0.0029 17.8 0.0 0.0059 16.8 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain DUF2973 PF11189.8 KLO13571.1 - 0.1 12.7 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) Synthase_beta PF11421.8 KLO13571.1 - 3.8 8.3 14.7 0.082 13.6 5.1 3.0 2 1 1 3 3 3 0 ATP synthase F1 beta subunit Med12 PF09497.10 KLO13572.1 - 1.8e-25 89.0 0.0 4.5e-25 87.7 0.0 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 KLO13572.1 - 3.5e-06 26.2 0.1 2.3e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain FUSC-like PF12805.7 KLO13572.1 - 0.094 11.8 0.4 0.19 10.8 0.4 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS BTB PF00651.31 KLO13574.1 - 0.017 15.4 0.0 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain BTB PF00651.31 KLO13575.1 - 0.04 14.1 0.1 0.12 12.6 0.1 1.9 1 1 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 KLO13576.1 - 0.0014 18.9 0.1 0.0063 16.7 0.0 2.2 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO13577.1 - 0.00029 21.0 0.0 0.00052 20.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain SelR PF01641.18 KLO13577.1 - 0.07 13.2 0.0 7.6 6.6 0.0 2.3 2 0 0 2 2 2 0 SelR domain p450 PF00067.22 KLO13578.1 - 3.1e-66 224.0 0.0 3.9e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.31 KLO13579.1 - 0.0011 19.2 0.0 0.0029 17.8 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO13580.1 - 1.1e-05 25.6 0.3 3e-05 24.2 0.0 1.9 3 0 0 3 3 3 1 BTB/POZ domain BTB PF00651.31 KLO13581.1 - 0.083 13.1 0.0 0.24 11.6 0.0 1.8 1 1 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 KLO13582.1 - 0.00031 20.9 0.0 0.00083 19.6 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO13583.1 - 0.0024 18.1 0.0 0.0065 16.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO13584.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 KLO13585.1 - 2.4e-05 24.5 0.0 4.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain ABM PF03992.16 KLO13586.1 - 0.0016 18.5 0.2 0.028 14.5 0.0 2.5 2 1 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Glyco_hydro_79C PF16862.5 KLO13587.1 - 2.1e-15 57.5 0.1 8.5e-15 55.5 0.0 2.1 1 1 1 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Methyltransf_23 PF13489.6 KLO13589.1 - 2.1e-13 50.4 0.0 2.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO13589.1 - 5.7e-12 46.2 0.0 1.2e-11 45.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO13589.1 - 2.4e-11 43.6 0.0 9.7e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO13589.1 - 2.9e-10 40.7 0.0 5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO13589.1 - 6.3e-09 35.5 0.0 2e-08 33.9 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KLO13589.1 - 4.8e-06 27.2 0.0 1.1e-05 26.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KLO13589.1 - 0.0017 18.3 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Peptidase_M16_C PF05193.21 KLO13592.1 - 0.076 13.0 0.0 0.097 12.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase M16 inactive domain Methyltransf_25 PF13649.6 KLO13593.1 - 2.8e-10 40.8 0.0 9.3e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO13593.1 - 1.4e-09 38.5 0.0 2.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO13593.1 - 6.9e-09 35.7 0.0 5.2e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO13593.1 - 2.9e-08 33.7 0.0 4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO13593.1 - 8.3e-08 31.8 0.0 2.4e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KLO13593.1 - 8.2e-05 23.3 0.0 0.00021 22.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KLO13593.1 - 0.099 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_25 PF13649.6 KLO13594.1 - 2.8e-11 44.0 0.0 1.6e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO13594.1 - 3.4e-10 39.7 0.0 1.7e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KLO13594.1 - 4.6e-09 36.8 0.0 8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO13594.1 - 7.4e-09 35.6 0.0 1.3e-07 31.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO13594.1 - 2.3e-08 34.1 0.0 3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO13594.1 - 0.0001 23.0 0.0 0.00063 20.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain HU-HIG PF18291.1 KLO13594.1 - 0.034 14.2 0.0 0.076 13.1 0.0 1.5 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif TPMT PF05724.11 KLO13594.1 - 0.038 13.6 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) ABM PF03992.16 KLO13595.1 - 0.013 15.6 0.0 0.078 13.1 0.0 2.2 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase SRP9-21 PF05486.12 KLO13595.1 - 0.078 13.4 0.7 4.5 7.7 0.1 2.2 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Sugar_tr PF00083.24 KLO13596.1 - 9.7e-87 291.7 16.9 1.1e-86 291.5 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO13596.1 - 9.9e-22 77.3 41.5 1.2e-14 54.0 16.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 KLO13596.1 - 0.17 11.8 2.8 0.16 11.9 0.4 2.2 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF3792 PF12670.7 KLO13596.1 - 1.1 9.5 17.8 0.13 12.5 2.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) DUF5077 PF16871.5 KLO13599.1 - 1e-57 195.2 1.8 1.6e-57 194.5 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) DUF3472 PF11958.8 KLO13599.1 - 6.6e-57 192.7 6.1 6.6e-57 192.7 6.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3472) DUF1690 PF07956.11 KLO13600.1 - 9.1e-27 94.2 6.8 2.6e-26 92.7 6.8 1.6 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Bac_luciferase PF00296.20 KLO13600.1 - 0.032 13.6 1.4 0.04 13.3 1.4 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase Rootletin PF15035.6 KLO13600.1 - 0.048 13.7 2.3 0.28 11.2 2.4 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TSP_NTD PF17804.1 KLO13600.1 - 0.1 12.8 0.9 0.15 12.3 0.7 1.4 1 1 0 1 1 1 0 Tail specific protease N-terminal domain CHCH PF06747.13 KLO13600.1 - 0.18 11.9 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 CHCH domain DUF2939 PF11159.8 KLO13600.1 - 0.2 12.1 2.4 1.7 9.1 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) GATA PF00320.27 KLO13601.1 - 3e-25 87.5 18.6 3.9e-15 55.2 3.3 2.4 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 KLO13601.1 - 2.3e-11 43.3 0.8 5e-11 42.2 0.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 KLO13601.1 - 0.048 13.8 5.1 2 8.6 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 KLO13601.1 - 0.098 12.8 4.8 0.75 10.0 0.9 3.1 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.12 KLO13601.1 - 0.31 10.6 7.2 0.49 10.0 0.8 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding eIF-5_eIF-2B PF01873.17 KLO13601.1 - 0.58 10.0 5.4 5.9 6.8 0.6 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Cytochrom_c3_2 PF14537.6 KLO13601.1 - 2.1 8.9 7.5 6.2 7.4 1.0 2.7 1 1 2 3 3 3 0 Cytochrome c3 Remorin_C PF03763.13 KLO13601.1 - 2.7 7.9 6.4 5.3 7.0 6.4 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region zf-ribbon_3 PF13248.6 KLO13601.1 - 4.2 6.9 5.9 8.4 6.0 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 KLO13601.1 - 4.9 7.3 10.5 25 5.0 0.8 2.6 1 1 1 2 2 2 0 Double zinc ribbon NOA36 PF06524.12 KLO13602.1 - 0.19 11.0 4.2 0.31 10.3 4.2 1.2 1 0 0 1 1 1 0 NOA36 protein Dicty_REP PF05086.12 KLO13602.1 - 6.1 4.7 6.2 8.9 4.2 6.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PhoLip_ATPase_C PF16212.5 KLO13604.1 - 6.8e-52 176.7 23.0 6.8e-52 176.7 23.0 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KLO13604.1 - 7.1e-17 60.9 6.5 1.7e-16 59.6 6.5 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KLO13604.1 - 1.1e-14 55.2 0.1 4.1e-12 46.8 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KLO13604.1 - 5.5e-14 52.1 0.0 5.5e-14 52.1 0.0 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KLO13604.1 - 1.1e-09 38.2 0.0 2.3e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KLO13604.1 - 0.0012 18.7 0.0 0.0027 17.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Chi-conotoxin PF16981.5 KLO13604.1 - 0.037 14.3 1.8 3.6 7.9 0.1 3.7 3 0 0 3 3 3 0 chi-Conotoxin or t superfamily NST1 PF13945.6 KLO13605.1 - 2.8e-53 180.9 0.3 2.8e-53 180.9 0.3 5.9 4 2 2 6 6 6 1 Salt tolerance down-regulator cEGF PF12662.7 KLO13606.1 - 0.034 14.1 0.3 0.094 12.7 0.3 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like NLRC4_HD PF17889.1 KLO13606.1 - 0.045 14.1 1.0 0.1 12.9 0.0 2.1 2 0 0 2 2 2 0 NLRC4 helical domain BTB PF00651.31 KLO13609.1 - 0.00068 19.8 0.0 0.0016 18.7 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain DUF5549 PF17703.1 KLO13610.1 - 0.66 9.6 3.5 1 9.0 3.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5549) BTB PF00651.31 KLO13611.1 - 2.2e-07 31.1 0.0 1.5e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO13612.1 - 3e-08 33.9 0.0 7.3e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO13613.1 - 0.0042 17.3 0.0 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Inositol_P PF00459.25 KLO13615.1 - 2.2e-53 181.5 0.0 2.4e-52 178.1 0.0 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.16 KLO13616.1 - 8.1e-28 97.3 22.6 3.5e-25 88.7 25.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S9 PF00326.21 KLO13617.1 - 5e-31 107.8 0.0 8.9e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KLO13617.1 - 1.1e-08 34.7 0.2 0.00035 19.9 0.2 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KLO13617.1 - 4.2e-06 26.6 1.2 0.046 13.3 1.1 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KLO13617.1 - 4.8e-05 23.0 0.0 0.00023 20.8 0.0 2.0 2 1 1 3 3 3 1 Dienelactone hydrolase family BAAT_C PF08840.11 KLO13617.1 - 0.00022 21.2 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KLO13617.1 - 0.072 12.8 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 KLO13617.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein PAM2 PF07145.15 KLO13618.1 - 1.3 8.9 6.8 0.35 10.7 2.8 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region PRR20 PF15708.5 KLO13619.1 - 0.0031 17.4 3.2 0.0047 16.9 3.2 1.2 1 0 0 1 1 1 1 Proline-rich protein family 20 DDE_3 PF13358.6 KLO13622.1 - 2.2e-09 37.3 0.0 4.6e-09 36.2 0.0 1.6 1 1 1 2 2 2 1 DDE superfamily endonuclease G-gamma PF00631.22 KLO13622.1 - 0.079 13.0 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 GGL domain DDE_3 PF13358.6 KLO13623.1 - 1.7e-14 53.8 0.0 4.1e-13 49.3 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease TPR_12 PF13424.6 KLO13624.1 - 0.26 11.6 1.0 0.66 10.3 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Macoilin PF09726.9 KLO13625.1 - 0.58 8.6 8.9 0.63 8.5 8.9 1.0 1 0 0 1 1 1 0 Macoilin family NAD_kinase PF01513.21 KLO13626.1 - 2.5e-59 200.9 0.0 3.3e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KLO13626.1 - 0.2 11.3 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Acetyltransf_13 PF13880.6 KLO13627.1 - 0.087 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase AbLIM_anchor PF16182.5 KLO13628.1 - 0.023 14.5 0.1 0.023 14.5 0.1 1.1 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM LCAT PF02450.15 KLO13629.1 - 3.8e-85 286.4 0.0 1.6e-84 284.4 0.0 1.8 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 KLO13629.1 - 0.0057 16.2 0.0 0.0093 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 KLO13629.1 - 0.0081 16.8 3.0 0.041 14.5 0.0 2.4 1 1 0 2 2 2 1 Alpha/beta hydrolase family FGase PF05013.12 KLO13629.1 - 0.012 15.9 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase Hydrolase_4 PF12146.8 KLO13629.1 - 0.052 12.8 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_2 PF01674.18 KLO13629.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) RRM_1 PF00076.22 KLO13630.1 - 2.6e-05 24.0 0.0 6.8e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.7 KLO13631.1 - 0.019 14.8 0.0 0.058 13.3 0.0 1.9 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KLO13631.1 - 0.024 14.5 0.7 0.14 12.1 0.0 2.7 3 0 0 3 3 3 0 F-box domain PspB PF06667.12 KLO13631.1 - 0.088 12.9 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Phage shock protein B LIG3_BRCT PF16759.5 KLO13632.1 - 0.18 12.1 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Glucosamine_iso PF01182.20 KLO13633.1 - 7.8e-23 81.5 0.0 1.2e-22 80.9 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase IGPS PF00218.21 KLO13634.1 - 1.1e-83 280.3 0.0 2e-83 279.5 0.0 1.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 KLO13634.1 - 8.5e-43 146.3 0.0 1.8e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 KLO13634.1 - 7.1e-41 140.1 0.2 8.7e-31 107.2 0.1 3.3 2 1 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 KLO13634.1 - 1.2e-06 28.5 0.5 4.7e-06 26.5 0.5 2.0 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KLO13634.1 - 5.1e-05 23.1 0.1 0.0068 16.2 0.1 3.4 4 0 0 4 4 4 1 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.18 KLO13634.1 - 0.0017 17.5 0.1 0.02 13.9 0.1 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Pkinase PF00069.25 KLO13635.1 - 3.1e-67 226.7 0.0 3.7e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13635.1 - 3.6e-28 98.5 0.0 5.1e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KLO13635.1 - 0.012 14.6 0.1 0.023 13.7 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 KLO13635.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO13635.1 - 0.051 13.5 0.2 0.18 11.7 0.1 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 KLO13635.1 - 0.17 12.8 0.0 0.47 11.4 0.0 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat Isochorismatase PF00857.20 KLO13636.1 - 7.9e-23 81.5 0.1 2.3e-22 80.0 0.1 1.7 1 1 0 1 1 1 1 Isochorismatase family Tetraspanin PF00335.20 KLO13638.1 - 5.4e-05 23.0 11.2 5.4e-05 23.0 11.2 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF5368 PF17336.2 KLO13638.1 - 0.0041 17.3 1.9 0.011 15.9 1.9 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5368) CitMHS PF03600.16 KLO13638.1 - 0.011 15.0 1.2 0.012 14.9 1.2 1.2 1 0 0 1 1 1 0 Citrate transporter Kei1 PF08552.11 KLO13638.1 - 8.2 6.3 13.6 0.62 9.9 0.2 2.4 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Tetraspanin PF00335.20 KLO13639.1 - 4e-05 23.4 12.4 7.9e-05 22.5 12.4 1.5 1 1 0 1 1 1 1 Tetraspanin family DUF5433 PF17498.2 KLO13639.1 - 0.037 14.2 0.1 0.037 14.2 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5433) APG9 PF04109.16 KLO13639.1 - 0.33 9.9 3.5 0.69 8.9 0.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg9 DUF4064 PF13273.6 KLO13639.1 - 1.3 9.3 8.1 0.59 10.4 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2070 PF09843.9 KLO13639.1 - 8.1 4.6 7.0 11 4.2 7.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) p450 PF00067.22 KLO13640.1 - 6e-61 206.6 0.0 5.7e-60 203.4 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 zf-MYND PF01753.18 KLO13641.1 - 4e-07 30.0 15.6 4e-07 30.0 15.6 1.7 2 0 0 2 2 2 1 MYND finger DUF3846 PF12957.7 KLO13641.1 - 0.18 12.2 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) zf-Mss51 PF13824.6 KLO13641.1 - 9 6.5 9.6 33 4.7 9.5 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_12 PF11331.8 KLO13643.1 - 0.094 12.5 0.2 0.23 11.3 0.2 1.7 1 0 0 1 1 1 0 Probable zinc-ribbon domain FGE-sulfatase PF03781.16 KLO13644.1 - 4.8e-18 65.7 1.9 5.9e-16 58.8 1.9 2.1 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KLO13644.1 - 8.9e-10 39.2 1.3 2.2e-09 37.9 1.3 1.7 1 0 0 1 1 1 1 DinB superfamily DUF4093 PF13331.6 KLO13645.1 - 0.16 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) FMN_dh PF01070.18 KLO13646.1 - 1.1e-118 396.2 0.0 1.4e-118 395.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KLO13646.1 - 5.9e-23 80.8 0.0 1.4e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KLO13646.1 - 0.00028 20.1 0.0 0.00045 19.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KLO13646.1 - 0.0003 19.9 0.0 0.00053 19.1 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KLO13646.1 - 0.13 11.5 0.0 14 4.9 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PI-PLC-X PF00388.19 KLO13647.1 - 1.9e-05 24.3 0.0 4.1e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Acetyltransf_1 PF00583.25 KLO13648.1 - 6.6e-06 26.4 0.0 9.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KLO13648.1 - 0.00014 22.3 0.0 0.00031 21.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO13648.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KLO13648.1 - 0.023 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KLO13648.1 - 0.042 14.0 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KLO13648.1 - 0.12 12.5 0.0 0.31 11.1 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MAAL_C PF07476.11 KLO13651.1 - 0.2 10.8 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus DPBB_1 PF03330.18 KLO13652.1 - 0.0016 18.7 0.0 0.0053 17.0 0.0 2.0 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KLO13652.1 - 0.03 14.2 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Barwin family Abhydrolase_3 PF07859.13 KLO13653.1 - 6.6e-40 137.2 0.2 8.9e-35 120.5 0.0 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO13653.1 - 7.5e-10 38.2 0.0 1.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KLO13653.1 - 0.013 14.4 0.2 0.077 11.8 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family IF2_assoc PF08364.11 KLO13653.1 - 0.097 12.9 0.1 0.33 11.2 0.1 1.9 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region Trypan_PARP PF05887.11 KLO13654.1 - 3e-06 27.3 56.1 0.0019 18.2 29.2 2.1 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 KLO13656.1 - 7.5e-62 209.1 0.0 9.3e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13656.1 - 4.3e-30 104.8 0.0 5.9e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO13656.1 - 5.1e-05 22.7 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO13656.1 - 0.0016 18.4 0.0 0.013 15.5 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO13656.1 - 0.088 12.4 0.0 2.9 7.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KLO13656.1 - 0.24 10.1 0.0 0.41 9.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CBP_BcsO PF17037.5 KLO13658.1 - 0.76 9.9 5.0 5.7 7.0 0.4 2.5 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO tRNA-synt_2b PF00587.25 KLO13660.1 - 4.8e-34 117.9 0.0 7.9e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KLO13660.1 - 2.9e-18 65.8 1.4 3e-18 65.7 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.21 KLO13660.1 - 8.8e-11 41.7 0.0 1.8e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KLO13660.1 - 5.5e-09 36.0 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Foie-gras_1 PF11817.8 KLO13661.1 - 1.2e-31 110.3 0.0 9.9e-21 74.5 0.0 3.5 3 1 0 3 3 3 2 Foie gras liver health family 1 TPR_6 PF13174.6 KLO13661.1 - 0.16 12.7 0.1 0.59 10.9 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KLO13661.1 - 0.24 11.6 1.3 0.69 10.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SAE2 PF08573.10 KLO13662.1 - 2.1e-15 57.8 2.9 2.1e-15 57.8 2.9 3.7 4 1 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Zip PF02535.22 KLO13662.1 - 0.16 11.1 0.8 0.21 10.8 0.4 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter Borrelia_REV PF03978.13 KLO13662.1 - 0.17 11.8 0.5 0.37 10.7 0.2 1.7 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein p450 PF00067.22 KLO13664.1 - 2.6e-41 141.9 0.0 9.4e-29 100.4 0.1 2.9 1 1 1 2 2 2 2 Cytochrome P450 SUR7 PF06687.12 KLO13665.1 - 8.5e-16 58.2 17.8 1.2e-15 57.7 17.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family Prominin PF05478.11 KLO13665.1 - 0.3 9.0 3.7 0.062 11.3 0.3 1.7 2 0 0 2 2 2 0 Prominin DUF975 PF06161.11 KLO13665.1 - 1 9.1 14.4 0.23 11.2 7.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF975) HflK_N PF12221.8 KLO13666.1 - 0.27 11.3 0.0 0.44 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial membrane protein N terminal PsbW PF07123.12 KLO13667.1 - 0.056 13.5 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Pyocin_S PF06958.12 KLO13669.1 - 0.052 14.1 0.4 0.12 12.9 0.4 1.5 1 1 0 1 1 1 0 S-type Pyocin DUF4407 PF14362.6 KLO13669.1 - 0.57 9.5 8.8 1 8.6 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ubiquitin PF00240.23 KLO13671.1 - 2.9e-07 30.1 0.2 3.7e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KLO13671.1 - 4.1e-05 23.9 0.7 8.3e-05 23.0 0.7 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 KLO13671.1 - 0.017 15.0 0.6 0.027 14.3 0.6 1.4 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 KLO13671.1 - 0.02 15.4 0.0 0.021 15.3 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Ubiquitin_4 PF18036.1 KLO13671.1 - 0.023 14.8 0.2 0.69 10.0 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain RAWUL PF16207.5 KLO13671.1 - 0.052 14.2 0.0 0.058 14.1 0.0 1.1 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like G-patch PF01585.23 KLO13673.1 - 2.7e-05 23.9 1.3 6.1e-05 22.8 0.3 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KLO13673.1 - 3.3e-05 23.9 0.3 3.3e-05 23.9 0.3 4.0 4 1 0 4 4 4 1 G-patch domain DUF4604 PF15377.6 KLO13673.1 - 0.58 10.6 43.1 0.14 12.6 15.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.12 KLO13673.1 - 1.4 8.7 32.8 1.3 8.8 11.8 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 KLO13673.1 - 3.6 7.6 47.9 2.9 7.9 21.4 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 TrkH PF02386.16 KLO13675.1 - 7.2e-100 334.8 12.7 1.8e-98 330.2 7.1 2.1 2 0 0 2 2 2 2 Cation transport protein Vps54 PF07928.12 KLO13675.1 - 0.087 13.3 0.1 0.71 10.3 0.0 2.1 2 0 0 2 2 2 0 Vps54-like protein AAA_12 PF13087.6 KLO13676.1 - 7.6e-16 58.3 0.0 1.8e-15 57.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KLO13676.1 - 1.9e-06 27.6 0.1 1.4e-05 24.8 0.1 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 KLO13677.1 - 0.00023 21.2 0.0 0.00094 19.2 0.0 2.1 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 KLO13677.1 - 0.013 15.6 1.7 0.024 14.7 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function DUF83 LCM PF04072.14 KLO13678.1 - 1.6e-20 73.9 0.0 4.2e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Tim17 PF02466.19 KLO13679.1 - 2.4e-33 114.8 9.2 2.9e-33 114.6 9.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family FMN_dh PF01070.18 KLO13680.1 - 4.4e-120 400.9 0.0 5.3e-120 400.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KLO13680.1 - 8.6e-21 73.9 0.0 2.3e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KLO13680.1 - 1.4e-05 24.4 0.0 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KLO13680.1 - 4.5e-05 22.6 0.2 0.00014 21.0 0.0 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KLO13680.1 - 0.049 13.0 0.1 0.072 12.5 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 KLO13680.1 - 0.064 12.5 0.0 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KLO13680.1 - 0.089 12.0 0.1 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KLO13680.1 - 0.11 11.9 0.1 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein F-box-like PF12937.7 KLO13681.1 - 8.2e-07 28.8 0.2 4.9e-06 26.3 0.0 2.4 2 1 0 2 2 2 1 F-box-like GABP-alpha PF11620.8 KLO13681.1 - 0.15 12.2 0.0 0.57 10.4 0.0 2.0 1 1 1 2 2 2 0 GA-binding protein alpha chain F-box-like PF12937.7 KLO13682.1 - 1.8e-08 34.1 0.1 4.8e-07 29.6 0.0 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO13682.1 - 0.013 15.4 1.6 0.028 14.3 0.0 2.5 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO13683.1 - 0.04 13.8 0.1 0.093 12.6 0.1 1.7 1 0 0 1 1 1 0 F-box-like Cellulase PF00150.18 KLO13684.1 - 8e-13 48.5 0.0 1.5e-12 47.5 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.22 KLO13686.1 - 3.6e-36 122.8 0.0 2.5e-20 72.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KLO13686.1 - 0.023 14.9 0.2 5 7.4 0.0 2.6 2 0 0 2 2 2 0 Poly-adenylate binding protein, unique domain Nup35_RRM PF05172.13 KLO13686.1 - 0.027 14.4 0.0 0.075 13.0 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KLO13686.1 - 0.041 13.9 0.0 0.51 10.4 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif GCN5L1 PF06320.13 KLO13688.1 - 0.05 13.8 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) SLY PF12485.8 KLO13689.1 - 0.058 14.1 2.2 0.24 12.1 2.2 2.0 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein zf-MYND PF01753.18 KLO13690.1 - 5.4e-08 32.8 9.0 1.1e-07 31.8 9.0 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO13691.1 - 2.8e-09 36.9 7.6 5.2e-09 36.1 7.6 1.5 1 0 0 1 1 1 1 MYND finger SPX PF03105.19 KLO13691.1 - 6.9 6.5 20.7 12 5.7 20.7 1.3 1 0 0 1 1 1 0 SPX domain DUF5393 PF17371.2 KLO13691.1 - 7.4 4.6 8.0 12 3.9 8.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) zf-Mss51 PF13824.6 KLO13691.1 - 10 6.3 8.1 2.3e+02 2.0 8.1 2.6 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 NTF2 PF02136.20 KLO13692.1 - 3.2e-28 98.7 0.0 5.1e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KLO13692.1 - 5.8e-07 29.2 0.0 9.7e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KLO13692.1 - 0.037 14.1 0.0 0.088 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Hydrophobin PF01185.18 KLO13693.1 - 3e-15 56.6 3.1 3.7e-15 56.3 3.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KLO13694.1 - 7e-15 55.4 2.3 8.8e-15 55.1 2.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin F-box-like PF12937.7 KLO13695.1 - 1.4e-10 40.9 0.6 1.4e-10 40.9 0.6 1.7 2 0 0 2 2 2 1 F-box-like NAD_binding_10 PF13460.6 KLO13697.1 - 2.2e-06 27.7 0.0 3.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KLO13697.1 - 1.3e-05 24.8 0.0 0.00021 20.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KLO13697.1 - 0.0037 16.9 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KLO13697.1 - 0.0087 16.3 0.0 0.03 14.6 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Semialdhyde_dh PF01118.24 KLO13697.1 - 0.047 14.1 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 KLO13698.1 - 3.4e-28 98.6 36.0 3.4e-28 98.6 36.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Zip PF02535.22 KLO13698.1 - 2.8 7.1 7.7 1.1 8.4 0.4 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter zf-MYND PF01753.18 KLO13699.1 - 1.3e-09 37.9 6.8 2.2e-09 37.2 6.8 1.4 1 0 0 1 1 1 1 MYND finger SH3_1 PF00018.28 KLO13700.1 - 1.1e-30 104.9 0.2 4.8e-10 38.9 0.1 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 KLO13700.1 - 5.6e-21 74.0 0.0 7.1e-06 25.6 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.6 KLO13700.1 - 3.4e-16 58.8 0.1 4.6e-05 23.2 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_10 PF17902.1 KLO13700.1 - 2.2e-06 27.6 0.0 0.053 13.6 0.0 3.3 2 1 0 2 2 2 2 SH3 domain Collectrin PF16959.5 KLO13701.1 - 0.85 9.4 3.1 9.4 6.0 0.8 2.3 2 0 0 2 2 2 0 Renal amino acid transporter zf-MYND PF01753.18 KLO13702.1 - 3.1e-09 36.7 8.4 5.1e-09 36.1 8.4 1.4 1 0 0 1 1 1 1 MYND finger Pkinase PF00069.25 KLO13704.1 - 9.3e-64 215.3 0.0 1.1e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13704.1 - 8.9e-27 94.0 0.0 1.3e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO13704.1 - 2.7e-06 26.9 0.0 4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO13704.1 - 0.0006 19.2 0.1 0.00096 18.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO13704.1 - 0.0027 17.3 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KLO13704.1 - 0.0039 17.1 0.3 0.7 9.8 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Phage_sheath_1C PF17482.2 KLO13704.1 - 0.041 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Phage tail sheath C-terminal domain YukC PF10140.9 KLO13704.1 - 0.097 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Mad3_BUB1_I PF08311.12 KLO13705.1 - 6.6e-32 110.1 0.1 9.9e-32 109.5 0.1 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KLO13706.1 - 1.2e-67 228.1 0.0 1.4e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13706.1 - 1.4e-30 106.4 0.0 3.7e-30 105.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KLO13706.1 - 0.003 16.9 0.1 0.0053 16.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KLO13706.1 - 0.0052 16.1 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KLO13706.1 - 0.017 14.1 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KLO13706.1 - 0.062 13.2 0.7 0.27 11.1 0.6 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KLO13706.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 BCDHK_Adom3 PF10436.9 KLO13707.1 - 1.6e-64 216.6 0.0 2.2e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KLO13707.1 - 1e-13 51.8 0.0 2.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KLO13707.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3719 PF12516.8 KLO13707.1 - 0.014 15.1 0.1 0.035 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) Ribosomal_L16 PF00252.18 KLO13709.1 - 1.9e-45 154.1 0.0 2.4e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e MTABC_N PF16185.5 KLO13712.1 - 0.069 12.6 0.1 0.079 12.5 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region CBF PF03914.17 KLO13713.1 - 2.2e-30 105.9 9.1 4.1e-30 105.1 1.9 3.3 3 1 0 3 3 3 1 CBF/Mak21 family Spore_coat_CotO PF14153.6 KLO13713.1 - 0.0059 16.6 1.5 0.015 15.3 1.5 1.5 1 0 0 1 1 1 1 Spore coat protein CotO Cnd1 PF12717.7 KLO13713.1 - 0.0061 16.6 0.2 2.7 8.0 0.0 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KLO13713.1 - 0.09 13.1 0.2 2.7 8.5 0.1 3.0 3 0 0 3 3 3 0 HEAT repeat CENP-B_dimeris PF09026.10 KLO13713.1 - 0.11 12.9 4.5 0.59 10.6 4.5 2.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KLO13713.1 - 5.3 6.3 6.0 9 5.5 6.0 1.3 1 0 0 1 1 1 0 NOA36 protein Hexapep PF00132.24 KLO13714.1 - 4.2e-10 39.0 14.6 0.0012 18.4 0.2 3.7 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KLO13714.1 - 0.0044 16.7 8.9 0.51 10.1 0.0 3.2 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase BTB PF00651.31 KLO13715.1 - 1e-08 35.4 0.0 4.8e-08 33.2 0.0 2.1 3 0 0 3 3 3 1 BTB/POZ domain CAP_GLY PF01302.25 KLO13715.1 - 1.1e-07 31.7 0.5 2.3e-06 27.5 0.4 2.4 2 0 0 2 2 2 1 CAP-Gly domain zf-CCCH_4 PF18044.1 KLO13716.1 - 3.8e-09 36.1 7.3 4e-05 23.3 0.6 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KLO13716.1 - 2.4e-08 34.6 4.7 0.00044 20.9 0.3 2.4 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KLO13716.1 - 3.5e-06 26.9 12.8 3.1e-05 23.9 1.7 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KLO13716.1 - 2.3e-05 24.1 6.9 0.00062 19.6 1.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KLO13716.1 - 0.00042 20.5 0.5 0.00077 19.7 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger containing family Syntaphilin PF15290.6 KLO13716.1 - 3.7 7.1 5.4 0.48 10.0 0.7 1.8 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp zf-CCCH_2 PF14608.6 KLO13716.1 - 7.1 7.3 11.9 0.26 11.8 2.3 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger PAS_9 PF13426.7 KLO13717.1 - 5.9e-28 97.2 0.0 5.6e-16 58.7 0.0 3.8 4 0 0 4 4 4 3 PAS domain PAS PF00989.25 KLO13717.1 - 3.5e-16 59.2 0.0 7.6e-05 22.7 0.0 4.2 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.12 KLO13717.1 - 6.2e-14 52.1 0.0 0.00057 20.1 0.0 4.5 4 0 0 4 4 4 4 PAS fold PAS_4 PF08448.10 KLO13717.1 - 2.1e-10 40.8 0.0 0.0026 18.0 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 KLO13717.1 - 1.2e-06 28.6 0.0 0.12 12.5 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS_8 PF13188.7 KLO13717.1 - 0.0027 17.7 0.0 0.61 10.2 0.0 2.8 3 0 0 3 3 3 1 PAS domain EIF_2_alpha PF07541.12 KLO13718.1 - 3.1e-27 95.0 0.0 7.9e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KLO13718.1 - 3.3e-14 53.0 1.7 6.1e-14 52.1 1.7 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Spindle_Spc25 PF08234.12 KLO13718.1 - 0.11 12.7 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 DUF1840 PF08895.11 KLO13718.1 - 0.38 11.1 4.5 4.8 7.6 1.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) Kinesin PF00225.23 KLO13719.1 - 4.5e-89 298.7 0.2 6.8e-89 298.1 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KLO13719.1 - 6.5e-18 65.1 0.0 1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding TPR_2 PF07719.17 KLO13719.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Cytochrom_B561 PF03188.16 KLO13720.1 - 7.7e-11 42.3 7.7 4.1e-10 39.9 7.3 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KLO13720.1 - 0.0022 18.2 12.7 2 8.6 3.9 3.6 2 1 1 3 3 3 3 Protein of unknown function (DUF4079) PRA1 PF03208.19 KLO13720.1 - 0.036 13.7 7.4 0.13 11.9 0.4 2.4 2 0 0 2 2 2 0 PRA1 family protein DUF4181 PF13789.6 KLO13720.1 - 1.1 9.5 6.3 4.2 7.7 1.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) MR_MLE_C PF13378.6 KLO13722.1 - 3.9e-48 163.9 0.5 6e-47 160.0 0.5 2.1 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KLO13722.1 - 4.2e-07 30.2 0.0 1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Peptidase_C25_C PF03785.14 KLO13722.1 - 0.017 14.9 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain MAAL_C PF07476.11 KLO13722.1 - 0.062 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Cauli_VI PF01693.16 KLO13724.1 - 1.8e-11 44.1 0.0 3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin DnaJ PF00226.31 KLO13725.1 - 2.4e-21 75.6 0.1 1.9e-20 72.8 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain tRNA-synt_2 PF00152.20 KLO13726.1 - 2.8e-84 282.9 0.0 3.5e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KLO13726.1 - 3.5e-06 26.9 0.0 7.8e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KLO13726.1 - 0.0089 15.5 0.1 2.3 7.6 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 KLO13726.1 - 0.033 14.2 0.0 0.42 10.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) WD40 PF00400.32 KLO13727.1 - 9.6e-32 108.5 14.7 2.9e-09 37.4 0.1 6.6 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO13727.1 - 8.6e-18 64.4 0.3 6.5e-06 26.4 0.0 5.1 3 3 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO13727.1 - 4.5e-07 29.2 0.2 0.031 13.2 0.0 3.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KLO13727.1 - 2.3e-06 27.6 0.0 0.044 13.6 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KLO13727.1 - 0.00062 18.4 0.0 0.44 9.0 0.0 3.1 3 0 0 3 3 3 1 Cytochrome D1 heme domain WD40_like PF17005.5 KLO13727.1 - 0.0032 16.9 0.0 0.79 9.0 0.0 2.6 2 0 0 2 2 2 2 WD40-like domain Nbas_N PF15492.6 KLO13727.1 - 0.0088 15.4 0.1 2.1 7.6 0.0 2.4 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KLO13727.1 - 0.011 14.4 0.1 0.52 8.9 0.0 2.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 ELYS-bb PF16687.5 KLO13727.1 - 0.027 13.1 0.0 0.23 10.0 0.0 2.0 1 1 0 1 1 1 0 beta-propeller of ELYS nucleoporin Pkinase PF00069.25 KLO13728.1 - 3e-28 98.9 0.0 3.8e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13728.1 - 4.8e-28 98.1 0.0 6.4e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO13728.1 - 0.012 14.4 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KLO13728.1 - 0.013 15.5 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KLO13728.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KLO13729.1 - 2.4e-67 227.0 0.0 5.5e-40 137.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KLO13729.1 - 2e-63 214.2 0.0 2e-42 145.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KLO13729.1 - 1.8e-07 30.8 0.0 0.015 14.7 0.0 2.7 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KLO13729.1 - 0.00059 19.5 1.0 0.86 9.2 0.0 3.2 3 0 0 3 3 3 2 RIO1 family ABC1 PF03109.16 KLO13729.1 - 0.014 15.5 0.0 0.046 13.9 0.0 1.8 2 0 0 2 2 2 0 ABC1 family Kdo PF06293.14 KLO13729.1 - 0.016 14.6 0.0 4.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phe_tRNA-synt_N PF02912.18 KLO13729.1 - 0.067 13.1 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain zf-MYND PF01753.18 KLO13730.1 - 4.2e-08 33.1 14.2 4.2e-08 33.1 14.2 2.2 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 KLO13730.1 - 0.17 12.0 3.7 0.38 10.9 3.7 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO13731.1 - 9.6e-08 32.0 16.0 1.6e-07 31.2 16.0 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO13732.1 - 3.6e-09 36.6 14.0 6e-09 35.8 14.0 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO13733.1 - 1.6e-08 34.5 14.0 3.8e-08 33.3 14.0 1.7 1 0 0 1 1 1 1 MYND finger DEAD PF00270.29 KLO13734.1 - 0.0049 16.6 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-MYND PF01753.18 KLO13735.1 - 2.2e-08 34.0 16.3 2.2e-08 34.0 16.3 2.1 2 0 0 2 2 2 1 MYND finger Peptidase_C13 PF01650.18 KLO13737.1 - 2.1e-42 145.4 0.3 2.7e-42 145.1 0.3 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 KLO13737.1 - 0.088 13.1 0.2 0.37 11.1 0.0 2.1 3 0 0 3 3 3 0 Mid domain of argonaute WD40 PF00400.32 KLO13738.1 - 1.8e-54 180.5 15.5 9.2e-09 35.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KLO13738.1 - 5.2e-26 90.8 5.8 9.6e-26 89.9 5.8 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KLO13738.1 - 2.5e-20 72.5 0.4 0.00036 20.8 0.0 6.3 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KLO13738.1 - 9.5e-09 35.0 0.0 0.043 13.1 0.0 4.5 4 1 1 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 KLO13738.1 - 3.2e-07 29.6 0.8 0.28 10.1 0.0 5.6 2 2 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KLO13738.1 - 3.8e-05 22.4 2.1 0.005 15.4 0.4 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.12 KLO13738.1 - 0.0005 19.9 0.0 13 5.8 0.0 5.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Atrophin-1 PF03154.15 KLO13738.1 - 0.0021 16.5 5.3 0.0021 16.5 5.3 2.3 2 0 0 2 2 2 1 Atrophin-1 family Peptidase_S9_N PF02897.15 KLO13738.1 - 0.0047 15.8 0.0 0.33 9.7 0.0 3.1 2 1 1 3 3 3 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Nbas_N PF15492.6 KLO13738.1 - 0.013 14.9 0.1 11 5.2 0.0 3.3 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KLO13738.1 - 0.036 12.7 0.3 1 7.9 0.1 3.0 2 2 2 4 4 4 0 Nucleoporin Nup120/160 Herpes_UL25 PF01499.16 KLO13738.1 - 0.058 11.9 2.3 0.09 11.3 2.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Med9 PF07544.13 KLO13738.1 - 0.074 13.1 0.9 0.17 12.0 0.9 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TMPIT PF07851.13 KLO13738.1 - 0.56 9.4 3.3 0.79 8.9 3.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein DASH_Spc19 PF08287.11 KLO13738.1 - 1.5 8.7 20.4 0.019 14.9 4.0 2.3 2 0 0 2 2 2 0 Spc19 F-box-like PF12937.7 KLO13739.1 - 5e-09 35.9 0.2 2.5e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO13740.1 - 2.6e-06 27.2 0.0 6.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like Lectin_leg-like PF03388.13 KLO13741.1 - 6.3e-65 218.7 0.1 8.2e-65 218.4 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KLO13741.1 - 1.5e-07 31.6 0.2 2.3e-07 31.1 0.2 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KLO13741.1 - 0.0036 16.9 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 2 Legume lectin domain zf-DNL PF05180.12 KLO13742.1 - 1e-27 95.8 0.5 1.4e-27 95.4 0.5 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-MYND PF01753.18 KLO13743.1 - 8.4e-09 35.4 14.2 1.9e-08 34.2 14.2 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO13744.1 - 5.5e-09 36.0 12.9 1e-08 35.1 12.9 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO13745.1 - 8.2e-09 35.4 12.3 1.4e-08 34.6 12.3 1.4 1 0 0 1 1 1 1 MYND finger PBP-Tp47_a PF14889.6 KLO13745.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a zf-MYND PF01753.18 KLO13746.1 - 5.4e-07 29.6 16.0 1e-06 28.7 16.0 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO13747.1 - 4.4e-06 26.7 18.8 7.4e-06 25.9 18.8 1.4 1 0 0 1 1 1 1 MYND finger Prok-RING_2 PF14445.6 KLO13747.1 - 0.049 13.8 9.3 0.16 12.1 6.4 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 zf-Mss51 PF13824.6 KLO13747.1 - 1 9.5 9.2 4.1 7.6 9.2 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO13748.1 - 5.4e-06 26.4 17.4 9e-06 25.7 17.4 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO13749.1 - 2e-06 27.8 15.5 3.5e-06 27.0 15.5 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO13750.1 - 9.7e-06 25.6 12.9 1.5e-05 25.0 12.9 1.3 1 0 0 1 1 1 1 MYND finger Ribosomal_L37e PF01907.19 KLO13750.1 - 0.012 15.8 5.9 0.044 13.9 5.3 2.1 2 0 0 2 2 2 0 Ribosomal protein L37e FYVE PF01363.21 KLO13750.1 - 0.13 12.4 5.7 0.23 11.6 5.7 1.3 1 0 0 1 1 1 0 FYVE zinc finger Prok-RING_2 PF14445.6 KLO13750.1 - 0.34 11.1 3.6 1.2 9.4 2.7 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 zf-MYND PF01753.18 KLO13751.1 - 1.3e-05 25.1 18.0 2.2e-05 24.4 18.0 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO13751.1 - 3.4 7.9 5.3 7.9 6.7 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Glyco_transf_22 PF03901.17 KLO13752.1 - 5.5e-81 272.9 12.8 9.3e-81 272.2 12.8 1.4 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family PRP38 PF03371.15 KLO13753.1 - 0.94 9.3 2.5 11 5.8 2.5 2.0 1 1 0 1 1 1 0 PRP38 family DUF423 PF04241.15 KLO13755.1 - 5.2e-20 71.4 2.0 9.3e-20 70.6 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF1741 PF08427.10 KLO13756.1 - 5.6e-35 121.1 0.8 9e-35 120.4 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) NUP50 PF08911.11 KLO13757.1 - 0.15 12.8 0.0 0.41 11.3 0.0 1.8 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) GDC-P PF02347.16 KLO13758.1 - 2.8e-184 613.0 0.0 3.1e-173 576.5 0.0 2.4 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KLO13758.1 - 0.028 13.7 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase PPR_2 PF13041.6 KLO13759.1 - 3.2e-16 59.2 0.5 0.085 13.1 0.1 7.9 6 1 2 8 8 7 3 PPR repeat family PPR_3 PF13812.6 KLO13759.1 - 2.9e-06 27.3 1.6 5.8 7.1 0.0 7.1 7 1 0 7 7 7 1 Pentatricopeptide repeat domain PPR PF01535.20 KLO13759.1 - 5e-06 26.4 13.9 0.52 10.7 0.0 8.3 8 1 0 8 8 8 2 PPR repeat PPR_1 PF12854.7 KLO13759.1 - 0.0022 17.7 2.2 4.9 6.9 0.0 5.6 6 0 0 6 6 6 1 PPR repeat Med2 PF11214.8 KLO13759.1 - 0.0055 16.8 2.2 0.0055 16.8 2.2 2.5 1 1 1 2 2 2 1 Mediator complex subunit 2 PDDEXK_1 PF12705.7 KLO13759.1 - 0.01 15.7 1.0 0.025 14.5 1.0 1.6 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily TrbM PF07424.11 KLO13759.1 - 0.051 13.5 0.5 0.13 12.2 0.5 1.7 1 0 0 1 1 1 0 TrbM IF-2B PF01008.17 KLO13759.1 - 0.076 12.2 5.2 0.17 11.1 5.2 1.5 1 0 0 1 1 1 0 Initiation factor 2 subunit family NYD-SP28_assoc PF14775.6 KLO13759.1 - 0.11 12.7 2.3 0.39 10.9 2.3 2.0 1 0 0 1 1 1 0 Sperm tail C-terminal domain Seryl_tRNA_N PF02403.22 KLO13759.1 - 0.21 11.8 8.5 0.18 12.0 5.6 2.4 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HSP70 PF00012.20 KLO13759.1 - 0.66 8.1 6.6 1.3 7.1 6.6 1.4 1 0 0 1 1 1 0 Hsp70 protein Cid2 PF09774.9 KLO13759.1 - 0.8 10.1 15.8 0.13 12.7 10.5 2.1 2 0 0 2 2 2 0 Caffeine-induced death protein 2 RNA_pol_Rpb1_5 PF04998.17 KLO13759.1 - 0.8 9.1 3.8 4.3 6.7 0.0 2.9 3 0 0 3 3 3 0 RNA polymerase Rpb1, domain 5 PAF-AH_p_II PF03403.13 KLO13759.1 - 1.2 7.5 4.5 0.92 7.9 0.0 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II AAA_23 PF13476.6 KLO13759.1 - 1.6 9.2 3.6 3 8.3 3.6 1.4 1 0 0 1 1 1 0 AAA domain Rgp1 PF08737.10 KLO13759.1 - 2.4 7.2 6.0 4.4 6.4 6.0 1.3 1 0 0 1 1 1 0 Rgp1 Sec8_exocyst PF04048.14 KLO13759.1 - 2.6 7.9 6.9 4.6 7.1 3.9 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Mis14 PF08641.12 KLO13759.1 - 6.3 7.1 10.7 0.9 9.8 0.7 3.3 1 1 1 2 2 2 0 Kinetochore protein Mis14 like Phage_GP20 PF06810.11 KLO13759.1 - 9.2 6.1 9.3 2.5 7.9 2.7 2.5 1 1 0 2 2 2 0 Phage minor structural protein GP20 DUF4870 PF09685.10 KLO13760.1 - 0.22 11.7 9.7 0.2 11.8 0.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4870) NAD_binding_4 PF07993.12 KLO13762.1 - 8.4e-33 113.6 0.0 1.2e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KLO13762.1 - 8.8e-30 103.6 0.0 3.2e-29 101.8 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KLO13762.1 - 1.2e-10 41.3 0.0 2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KLO13762.1 - 0.00041 20.6 0.0 0.00099 19.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KLO13762.1 - 0.04 12.9 0.0 0.12 11.4 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KLO13762.1 - 0.19 12.2 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KLO13764.1 - 3.8e-35 121.3 0.0 5.7e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KLO13764.1 - 8.2e-29 100.4 0.0 5.8e-28 97.6 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KLO13764.1 - 4.7e-11 42.6 0.0 8.2e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO13764.1 - 0.0017 17.4 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 KLO13764.1 - 0.0019 18.5 0.0 0.0068 16.7 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KLO13764.1 - 0.0042 16.5 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KLO13764.1 - 0.088 12.7 0.0 0.32 10.9 0.0 2.0 1 1 0 1 1 1 0 KR domain DUF5403 PF17395.2 KLO13765.1 - 0.043 14.1 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5403) TMEM208_SND2 PF05620.11 KLO13768.1 - 1 9.1 4.3 9.8 5.9 0.3 2.9 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 zf-C3HC4_2 PF13923.6 KLO13769.1 - 9e-11 41.4 8.8 1.8e-10 40.5 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO13769.1 - 2.5e-09 36.8 8.7 4.7e-09 36.0 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO13769.1 - 8.9e-08 32.4 7.2 2.1e-07 31.2 7.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KLO13769.1 - 2.6e-07 30.4 8.2 6.1e-07 29.2 8.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO13769.1 - 6.6e-07 29.2 7.4 1.5e-06 28.0 7.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain SUR7 PF06687.12 KLO13769.1 - 6.5e-06 25.9 0.0 9.2e-05 22.2 0.0 2.1 1 1 1 2 2 2 1 SUR7/PalI family Prok-RING_4 PF14447.6 KLO13769.1 - 1.8e-05 24.5 9.1 3.4e-05 23.6 9.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KLO13769.1 - 8.4e-05 22.5 6.8 0.0002 21.3 6.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KLO13769.1 - 0.0009 19.5 4.8 0.0023 18.2 4.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KLO13769.1 - 0.0033 17.6 7.9 0.0076 16.4 7.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KLO13769.1 - 0.012 15.3 5.6 0.046 13.5 5.6 2.1 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 KLO13769.1 - 0.061 13.1 7.2 0.19 11.5 7.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Amastin PF07344.11 KLO13769.1 - 0.064 13.1 1.1 0.15 11.9 1.1 1.7 1 1 0 1 1 1 0 Amastin surface glycoprotein Claudin_2 PF13903.6 KLO13769.1 - 0.071 12.9 0.9 0.11 12.2 0.7 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction zf-RING_10 PF16685.5 KLO13769.1 - 0.53 10.4 7.1 0.99 9.6 7.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 KLO13769.1 - 1.7 8.8 11.9 1.2 9.3 3.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) Abhydrolase_9_N PF15420.6 KLO13771.1 - 0.32 11.0 7.1 2.9 7.8 0.2 2.4 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF1218 PF06749.12 KLO13773.1 - 0.0008 19.9 2.3 0.56 10.8 0.0 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF1218) BatA PF07584.11 KLO13775.1 - 0.088 13.2 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal AA_permease PF00324.21 KLO13776.1 - 1.3e-124 416.5 34.7 1.6e-124 416.1 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KLO13776.1 - 2.5e-33 115.6 37.6 3.1e-33 115.3 37.6 1.1 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 KLO13777.1 - 3.6e-05 23.8 11.1 5.5e-05 23.2 11.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase_fungal PF17667.1 KLO13780.1 - 9.3e-85 284.8 0.0 1.3e-84 284.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO13780.1 - 1.2e-06 28.1 0.1 3.1e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Zn_clus PF00172.18 KLO13780.1 - 0.0056 16.8 8.1 0.0056 16.8 8.1 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 KLO13780.1 - 0.036 14.0 0.3 0.036 14.0 0.3 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family MFS_1 PF07690.16 KLO13781.1 - 6.3e-36 124.0 19.4 8.7e-36 123.6 19.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1180 PF06679.12 KLO13781.1 - 0.0086 16.5 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) OSTbeta PF15048.6 KLO13781.1 - 0.046 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF2070 PF09843.9 KLO13781.1 - 9.3 4.4 17.8 2.3 6.4 9.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Tristanin_u2 PF16638.5 KLO13782.1 - 0.17 12.7 1.7 0.25 12.2 1.7 1.4 1 1 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers Ipi1_N PF12333.8 KLO13784.1 - 1.2e-20 73.9 7.3 1.2e-19 70.8 0.7 3.9 3 1 0 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.7 KLO13784.1 - 0.0016 18.5 0.1 0.0036 17.4 0.1 1.5 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KLO13784.1 - 0.043 12.4 0.2 0.077 11.5 0.2 1.3 1 0 0 1 1 1 0 Adaptin N terminal region FmdA_AmdA PF03069.15 KLO13785.1 - 0.22 10.3 0.0 0.25 10.1 0.0 1.0 1 0 0 1 1 1 0 Acetamidase/Formamidase family RhoGEF PF00621.20 KLO13786.1 - 1.6e-41 142.6 0.0 3.3e-41 141.5 0.0 1.5 2 0 0 2 2 2 1 RhoGEF domain LRR_8 PF13855.6 KLO13786.1 - 1e-07 31.6 8.3 0.00085 19.0 0.8 2.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KLO13786.1 - 7.2e-05 23.1 7.3 0.046 14.2 0.3 3.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KLO13786.1 - 1.3 9.8 5.3 7.9 7.5 0.1 3.8 3 1 0 3 3 3 0 Leucine Rich Repeat zf-RING_5 PF14634.6 KLO13787.1 - 2.6e-06 27.3 2.9 6.1e-06 26.1 2.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KLO13787.1 - 4e-05 23.4 2.5 0.00012 21.9 2.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO13787.1 - 0.00025 21.3 2.4 0.00025 21.3 2.4 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KLO13787.1 - 0.00031 20.7 2.2 0.00085 19.3 2.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KLO13787.1 - 0.0082 16.0 1.9 0.02 14.7 1.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KLO13787.1 - 0.013 15.4 4.8 0.037 13.9 4.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KLO13787.1 - 0.023 14.9 1.8 0.057 13.6 0.4 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KLO13787.1 - 0.038 13.7 6.7 0.24 11.2 6.7 2.3 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KLO13787.1 - 0.33 10.8 9.9 0.14 12.1 5.7 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.7 KLO13788.1 - 1.5e-06 28.0 1.1 1.5e-06 28.0 1.1 2.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO13788.1 - 6.4e-06 25.9 5.3 1.5e-05 24.7 5.3 1.7 1 0 0 1 1 1 1 F-box domain F-box PF00646.33 KLO13790.1 - 9.9e-05 22.1 2.4 0.00021 21.1 2.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO13790.1 - 0.0011 18.8 0.3 0.0022 17.8 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO13791.1 - 4.5e-06 26.4 4.7 4.5e-06 26.4 4.7 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KLO13791.1 - 1.7e-05 24.6 0.9 5.1e-05 23.1 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO13792.1 - 5.5e-07 29.3 3.6 1.1e-06 28.4 3.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO13792.1 - 0.00096 19.0 0.7 0.0025 17.7 0.7 1.7 1 0 0 1 1 1 1 F-box-like Glyco_transf_8 PF01501.20 KLO13793.1 - 5.8e-13 49.0 0.0 1.8e-11 44.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 HET PF06985.11 KLO13795.1 - 5.9e-07 29.9 1.2 0.00026 21.3 0.0 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Pkinase_fungal PF17667.1 KLO13796.1 - 1.3e-90 304.1 0.0 1.7e-90 303.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO13796.1 - 2.2e-06 27.2 0.5 0.0001 21.8 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13796.1 - 0.04 13.2 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase DNA_pol_phi PF04931.13 KLO13796.1 - 0.9 7.6 4.5 1.5 6.8 4.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi Importin_rep_6 PF18829.1 KLO13796.1 - 2.1 8.5 7.6 43 4.3 0.0 2.9 3 0 0 3 3 3 0 Importin repeat 6 NOA36 PF06524.12 KLO13796.1 - 7.7 5.7 7.1 14 4.9 7.1 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KLO13796.1 - 9.9 6.6 10.6 26 5.3 10.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BTB PF00651.31 KLO13797.1 - 1.2e-05 25.4 0.0 2.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain IBR PF01485.21 KLO13798.1 - 6.1e-11 42.4 21.4 1.8e-05 24.9 10.0 2.4 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain SH3_1 PF00018.28 KLO13799.1 - 1.3e-11 43.9 0.1 2.5e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KLO13799.1 - 2.4e-08 33.7 0.0 4.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KLO13799.1 - 1.8e-05 24.3 0.0 3.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 KLO13799.1 - 0.00085 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain TMEM192 PF14802.6 KLO13799.1 - 0.66 9.0 2.2 0.48 9.5 0.7 1.5 1 1 1 2 2 2 0 TMEM192 family DUF4748 PF15932.5 KLO13800.1 - 0.018 14.8 0.1 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Plasmod_Pvs28 PF06247.11 KLO13800.1 - 0.076 13.3 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 Pvs28 EGF domain DUF4231 PF14015.6 KLO13801.1 - 4.9 7.7 5.3 0.89 10.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Phi-29_GP4 PF05464.11 KLO13804.1 - 0.091 13.0 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) NCD3G PF07562.14 KLO13805.1 - 0.032 14.2 3.3 0.032 14.2 3.3 1.7 2 1 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR zf-H2C2_2 PF13465.6 KLO13805.1 - 0.094 13.2 2.9 0.3 11.6 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-HIT PF04438.16 KLO13805.1 - 1.2 9.0 11.0 1.1 9.2 0.2 2.5 3 0 0 3 3 3 0 HIT zinc finger APH PF01636.23 KLO13806.1 - 2.1e-13 50.7 0.1 1.1e-08 35.4 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KLO13806.1 - 5.4e-09 35.9 0.1 9.6e-09 35.1 0.1 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KLO13806.1 - 0.02 14.5 0.5 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 KLO13806.1 - 0.081 12.3 0.0 13 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain CBM_19 PF03427.13 KLO13807.1 - 0.02 14.8 0.9 0.02 14.8 0.9 2.0 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) GILT PF03227.16 KLO13807.1 - 0.039 14.2 2.2 0.091 13.0 2.2 1.7 1 1 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Beta-lactamase PF00144.24 KLO13808.1 - 9.2e-44 150.0 0.0 2e-43 148.9 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KLO13808.1 - 4.3e-05 23.9 0.0 0.00012 22.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase PF00144.24 KLO13809.1 - 9.6e-30 103.9 0.2 1.6e-29 103.2 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KLO13809.1 - 0.0022 18.4 0.1 0.0073 16.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) p450 PF00067.22 KLO13810.1 - 9.5e-67 225.7 0.0 2.5e-66 224.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KLO13811.1 - 2.5e-09 36.9 0.7 5.3e-09 35.8 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO13811.1 - 0.00012 21.8 0.4 0.0011 18.7 0.4 2.4 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KLO13811.1 - 0.041 14.3 2.8 12 6.5 0.5 4.6 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) Methyltransf_11 PF08241.12 KLO13812.1 - 6.6e-10 39.5 0.0 9.6e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO13812.1 - 9.7e-10 39.0 0.0 1.8e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO13812.1 - 4e-09 36.5 0.0 7.2e-09 35.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO13812.1 - 7.6e-09 35.5 0.0 2.7e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO13812.1 - 2.8e-05 24.8 0.0 5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KLO13812.1 - 0.0016 18.6 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 KLO13812.1 - 0.0034 17.0 0.0 0.0067 16.0 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 KLO13812.1 - 0.033 13.7 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.18 KLO13812.1 - 0.05 12.9 0.0 1.6 8.0 0.0 2.8 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Abhydrolase_6 PF12697.7 KLO13813.1 - 2e-13 51.5 0.0 2.5e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO13813.1 - 0.0085 15.4 0.0 0.017 14.4 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 HSP70 PF00012.20 KLO13814.1 - 0.011 14.0 0.1 0.021 13.0 0.1 1.4 1 0 0 1 1 1 0 Hsp70 protein MFS_1 PF07690.16 KLO13815.1 - 2.2e-33 115.7 29.8 2.2e-33 115.7 29.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KLO13815.1 - 0.011 14.6 4.6 0.044 12.7 0.0 2.8 1 1 2 3 3 3 0 MFS_1 like family Phage_holin_3_3 PF16083.5 KLO13815.1 - 0.059 13.5 13.5 0.63 10.2 1.6 3.8 3 1 0 3 3 3 0 LydA holin phage, holin superfamily III DUF3810 PF12725.7 KLO13815.1 - 0.21 10.9 1.4 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Phage_holin_3_1 PF05106.12 KLO13815.1 - 4.7 7.7 5.8 7.5 7.1 0.1 3.3 3 1 0 3 3 3 0 Phage holin family (Lysis protein S) Exo_endo_phos PF03372.23 KLO13816.1 - 3.2e-06 26.8 0.0 6.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SMC_N PF02463.19 KLO13817.1 - 5.8e-69 231.9 0.2 1e-68 231.1 0.2 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KLO13817.1 - 2.5e-25 89.0 0.0 1.4e-24 86.6 0.0 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KLO13817.1 - 6.6e-16 59.4 19.2 6.6e-16 59.4 19.2 6.6 2 2 3 5 5 2 1 AAA domain AAA_21 PF13304.6 KLO13817.1 - 5.3e-14 52.7 6.1 9.2e-06 25.7 4.6 3.3 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KLO13817.1 - 5.3e-09 36.2 47.0 3.5e-07 30.3 11.2 4.5 2 2 0 2 2 2 2 AAA ATPase domain APG6_N PF17675.1 KLO13817.1 - 2.7e-05 24.7 1.0 2.7e-05 24.7 1.0 7.7 4 2 0 5 5 4 3 Apg6 coiled-coil region Spc7 PF08317.11 KLO13817.1 - 0.0006 18.8 18.7 0.0006 18.8 18.7 6.6 3 2 3 6 6 6 3 Spc7 kinetochore protein GAS PF13851.6 KLO13817.1 - 0.001 18.5 2.1 0.001 18.5 2.1 7.4 2 2 6 8 8 8 2 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KLO13817.1 - 0.0025 17.8 13.3 0.0025 17.8 13.3 9.2 4 2 5 10 10 9 4 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 KLO13817.1 - 0.009 16.2 3.5 0.009 16.2 3.5 7.0 3 2 2 7 7 7 1 Fibrinogen alpha/beta chain family FtsK_SpoIIIE PF01580.18 KLO13817.1 - 0.012 15.0 0.1 0.12 11.7 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KLO13817.1 - 0.021 14.6 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Occludin_ELL PF07303.13 KLO13817.1 - 0.14 12.9 0.2 0.14 12.9 0.2 8.3 6 3 2 8 8 8 0 Occludin homology domain Sec34 PF04136.15 KLO13817.1 - 0.9 9.4 51.2 0.043 13.7 2.4 7.2 7 1 0 7 7 7 0 Sec34-like family ABC_tran PF00005.27 KLO13817.1 - 1.2 9.7 0.0 1.2 9.7 0.0 5.8 3 2 0 3 3 2 0 ABC transporter F-box-like PF12937.7 KLO13818.1 - 0.00078 19.3 0.0 0.0041 17.0 0.0 2.4 3 1 0 3 3 3 1 F-box-like PPR_2 PF13041.6 KLO13819.1 - 0.014 15.6 0.0 0.58 10.4 0.0 3.0 2 1 0 2 2 2 0 PPR repeat family MFS_1 PF07690.16 KLO13820.1 - 1.1e-15 57.4 17.9 3.1e-15 56.0 16.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KLO13820.1 - 4.1e-13 49.4 10.8 6.8e-13 48.7 6.0 2.8 2 1 0 2 2 2 1 Nodulin-like DUF3188 PF11384.8 KLO13820.1 - 0.58 9.9 4.5 0.99 9.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) DUF4229 PF14012.6 KLO13820.1 - 0.66 10.1 0.0 0.66 10.1 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) Tcf25 PF04910.14 KLO13821.1 - 6.9e-92 308.2 0.0 9e-92 307.8 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF2225 PF09986.9 KLO13821.1 - 0.053 13.2 0.1 0.093 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_12 PF13424.6 KLO13821.1 - 0.059 13.7 0.1 0.059 13.7 0.1 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KLO13821.1 - 0.33 11.9 3.2 2.9 9.0 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Herpes_DNAp_acc PF04929.12 KLO13821.1 - 0.51 9.3 3.5 1.1 8.2 3.5 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SRP-alpha_N PF04086.13 KLO13821.1 - 3.3 7.6 16.3 6.3 6.6 16.3 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal p450 PF00067.22 KLO13822.1 - 5.1e-68 229.9 0.0 6.6e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO13823.1 - 1.6e-61 208.5 0.0 5.3e-61 206.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Beta-lactamase PF00144.24 KLO13824.1 - 1.6e-45 155.8 0.0 2.4e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KLO13824.1 - 0.0049 17.3 1.9 0.011 16.2 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) DEC-1_C PF04626.13 KLO13824.1 - 0.18 12.2 0.1 0.4 11.1 0.1 1.5 1 0 0 1 1 1 0 Dec-1 protein, C terminal region p450 PF00067.22 KLO13825.1 - 2.8e-61 207.7 0.0 5.6e-61 206.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 SNO PF01174.19 KLO13826.1 - 2.8e-47 161.0 0.0 1.5e-45 155.4 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KLO13826.1 - 6.3e-08 32.5 0.0 8.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 KLO13826.1 - 0.0001 22.1 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 KLO13826.1 - 0.0077 16.0 0.1 0.079 12.7 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KLO13826.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family Malic_M PF03949.15 KLO13826.1 - 0.075 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain PNP_UDP_1 PF01048.20 KLO13827.1 - 1.3e-36 126.0 0.0 1.6e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily A_thal_3526 PF09713.10 KLO13827.1 - 0.11 12.7 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Patatin PF01734.22 KLO13828.1 - 5.7e-19 69.1 0.2 4.5e-18 66.2 0.2 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase p450 PF00067.22 KLO13829.1 - 1.4e-69 235.0 0.0 3e-69 234.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PAM2 PF07145.15 KLO13829.1 - 0.62 9.9 4.1 0.39 10.5 1.3 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region p450 PF00067.22 KLO13830.1 - 4.5e-61 207.0 0.0 4.1e-60 203.9 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Peroxidase_2 PF01328.17 KLO13831.1 - 1.6e-46 159.2 0.0 2.2e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 HD PF01966.22 KLO13832.1 - 2.6e-13 50.3 0.3 9.2e-13 48.5 0.0 2.1 3 0 0 3 3 3 1 HD domain PDEase_I PF00233.19 KLO13832.1 - 0.043 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Peptidase_S10 PF00450.22 KLO13835.1 - 3.6e-75 254.0 1.3 2e-74 251.5 1.3 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase 2OG-FeII_Oxy_2 PF13532.6 KLO13836.1 - 1.8e-27 96.8 0.0 2.1e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BAAT_C PF08840.11 KLO13836.1 - 0.025 14.5 0.0 0.059 13.3 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal RasGEF PF00617.19 KLO13837.1 - 7.5e-27 94.7 0.0 1.8e-26 93.4 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KLO13837.1 - 4.7e-06 26.8 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF2070 PF09843.9 KLO13838.1 - 4.8 5.3 6.8 6.9 4.8 6.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PH PF00169.29 KLO13839.1 - 0.0015 19.0 0.0 0.0035 17.8 0.0 1.5 1 0 0 1 1 1 1 PH domain Spt5_N PF11942.8 KLO13839.1 - 5 8.2 8.2 5.3 8.1 2.6 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Gpr1_Fun34_YaaH PF01184.19 KLO13840.1 - 0.036 13.7 7.5 0.025 14.2 4.2 2.0 2 0 0 2 2 2 0 GPR1/FUN34/yaaH family Tetraspanin PF00335.20 KLO13840.1 - 3.7 7.2 12.4 15 5.2 12.4 2.0 1 1 0 1 1 1 0 Tetraspanin family RFC1 PF08519.12 KLO13842.1 - 8.8e-55 185.2 0.0 8.8e-55 185.2 0.0 3.0 4 0 0 4 4 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KLO13842.1 - 6.1e-15 55.4 0.0 1.5e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KLO13842.1 - 1.4e-09 38.4 0.0 3.9e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KLO13842.1 - 1e-06 28.8 0.1 3.2e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 KLO13842.1 - 0.003 17.6 0.0 0.011 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KLO13842.1 - 0.0039 17.0 0.0 0.012 15.4 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KLO13842.1 - 0.0048 16.6 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KLO13842.1 - 0.0056 17.2 0.3 0.021 15.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 KLO13842.1 - 0.0072 16.6 0.0 0.034 14.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO13842.1 - 0.01 16.2 0.0 0.031 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KLO13842.1 - 0.017 15.2 0.0 0.12 12.4 0.0 2.5 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KLO13842.1 - 0.018 15.0 0.2 0.068 13.1 0.1 2.0 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 KLO13842.1 - 0.023 14.9 0.1 0.46 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta PF06144.13 KLO13842.1 - 0.039 13.7 0.7 0.1 12.4 0.1 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Sigma54_activat PF00158.26 KLO13842.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 KLO13842.1 - 0.12 12.8 3.0 8.1 6.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 KLO13842.1 - 0.24 11.6 2.3 0.6 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KLO13842.1 - 1.2 9.7 5.8 3.9 8.0 0.0 4.1 4 1 0 4 4 4 0 ABC transporter RasGEF PF00617.19 KLO13843.1 - 3.1e-21 76.4 0.4 1.2e-20 74.5 0.0 2.1 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KLO13843.1 - 2.4e-05 24.5 0.0 6.8e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif RasGAP PF00616.19 KLO13845.1 - 3e-32 112.0 0.0 4.7e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase DUF3124 PF11322.8 KLO13845.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) DNA_binding_1 PF01035.20 KLO13847.1 - 2.6e-24 85.2 0.0 3.9e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Abhydrolase_1 PF00561.20 KLO13848.1 - 7.3e-17 61.8 2.0 3.9e-16 59.5 2.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO13848.1 - 1.2e-12 49.0 2.1 1.7e-12 48.4 2.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO13848.1 - 4.9e-08 32.5 0.0 2.3e-07 30.4 0.0 2.1 3 0 0 3 3 3 1 Serine aminopeptidase, S33 EHN PF06441.12 KLO13848.1 - 0.0034 17.7 0.1 0.014 15.8 0.1 2.0 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Ndr PF03096.14 KLO13848.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family Spt5-NGN PF03439.13 KLO13849.1 - 1.3e-06 28.2 0.0 2.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KLO13849.1 - 0.0037 17.2 16.0 0.63 10.1 0.4 5.9 6 0 0 6 6 6 2 KOW motif DUF5060 PF16586.5 KLO13849.1 - 0.061 13.7 0.1 1.8 9.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) TOBE_2 PF08402.10 KLO13849.1 - 0.07 13.3 0.8 0.61 10.3 0.2 2.8 2 0 0 2 2 2 0 TOBE domain 3HBOH PF10605.9 KLO13849.1 - 0.19 9.9 0.0 0.28 9.4 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) WD40_alt PF14077.6 KLO13850.1 - 0.052 13.4 0.9 0.14 12.0 0.3 2.0 2 0 0 2 2 2 0 Alternative WD40 repeat motif Pkinase PF00069.25 KLO13852.1 - 2.9e-25 89.1 0.0 6.9e-25 87.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13852.1 - 1.6e-21 76.8 0.0 4.8e-21 75.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Sigma70_ner PF04546.13 KLO13852.1 - 0.048 13.5 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Pkinase PF00069.25 KLO13853.1 - 1.3e-07 31.2 0.0 3.1e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KLO13853.1 - 0.0022 17.0 0.0 0.0032 16.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KLO13853.1 - 0.0081 15.0 0.0 0.0094 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KLO13853.1 - 0.0095 15.2 0.0 0.022 14.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO13854.1 - 2.3e-05 23.9 0.0 0.003 16.9 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase PF00069.25 KLO13855.1 - 1.4e-08 34.4 0.0 9.5e-08 31.7 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13855.1 - 0.0014 17.9 0.0 0.0032 16.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO13855.1 - 0.026 14.4 1.1 2.4 8.0 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO13855.1 - 0.052 12.3 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KLO13856.1 - 5.7e-08 32.4 0.0 2.8e-06 26.9 0.0 2.5 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13856.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KLO13857.1 - 1.9e-09 37.3 0.3 6.6e-08 32.2 0.0 2.6 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13857.1 - 0.0018 17.6 0.1 0.0039 16.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 KLO13857.1 - 0.082 12.5 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KLO13858.1 - 1e-08 34.9 0.0 1.4e-06 27.9 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KLO13858.1 - 0.019 13.8 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KLO13858.1 - 0.032 14.2 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KLO13858.1 - 0.072 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KLO13860.1 - 1.4e-26 93.5 0.0 1.8e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13860.1 - 2e-20 73.2 0.0 3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KLO13860.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CENP-F_leu_zip PF10473.9 KLO13861.1 - 0.0037 17.3 19.4 0.0037 17.3 19.4 7.4 2 1 5 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KLO13861.1 - 6.2 5.6 127.4 0.12 11.3 19.3 6.6 1 1 6 8 8 8 0 Spc7 kinetochore protein Pkinase PF00069.25 KLO13862.1 - 1.6e-10 40.8 0.0 8.7e-09 35.1 0.0 2.7 1 1 2 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13862.1 - 0.00015 21.1 0.0 0.00061 19.1 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 KLO13862.1 - 0.022 14.4 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KLO13862.1 - 0.088 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KLO13863.1 - 1.4e-21 77.0 0.0 2.5e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13863.1 - 1.1e-14 54.3 0.0 1.7e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO13863.1 - 9.5e-05 22.4 0.3 0.00023 21.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KLO13863.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO13863.1 - 0.02 14.5 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.20 KLO13863.1 - 0.023 14.0 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase WD40 PF00400.32 KLO13864.1 - 4.7e-07 30.4 0.3 0.00014 22.6 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO13864.1 - 0.027 14.8 0.0 0.077 13.3 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 KLO13867.1 - 5.4e-43 147.2 0.0 7.9e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13867.1 - 7.7e-40 136.8 0.0 1.1e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO13867.1 - 1.4e-06 27.4 0.0 2.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO13867.1 - 0.00099 18.5 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO13867.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO13867.1 - 0.024 14.3 0.1 0.15 11.6 0.0 2.0 1 1 0 2 2 2 0 RIO1 family Asp PF00026.23 KLO13868.1 - 1.4e-10 41.1 0.0 2.6e-06 27.1 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic aspartyl protease HEAT PF02985.22 KLO13870.1 - 2.1e-13 49.2 17.8 0.013 15.7 0.1 10.4 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 KLO13870.1 - 6.5e-12 45.7 21.5 0.011 16.2 2.0 8.7 7 2 3 10 10 10 6 HEAT repeats HEAT_EZ PF13513.6 KLO13870.1 - 9.4e-08 32.4 37.0 0.017 15.6 0.1 12.4 11 2 3 14 14 14 4 HEAT-like repeat IBN_N PF03810.19 KLO13870.1 - 1e-05 25.4 0.3 4e-05 23.4 0.3 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain IFRD PF05004.13 KLO13870.1 - 0.00017 20.8 0.3 1.1 8.3 0.0 3.5 3 0 0 3 3 3 2 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.8 KLO13870.1 - 0.00033 20.6 1.3 5.1 7.0 0.0 5.8 6 1 1 7 7 7 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KLO13870.1 - 0.00079 19.5 0.0 13 5.8 0.0 4.1 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 AAA_16 PF13191.6 KLO13870.1 - 0.039 14.3 0.9 2.2 8.7 0.0 3.7 3 0 0 3 3 3 0 AAA ATPase domain Ipi1_N PF12333.8 KLO13870.1 - 0.15 12.7 0.0 2.7 8.6 0.0 3.2 4 1 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Orbi_VP4 PF05059.12 KLO13872.1 - 0.14 10.1 0.0 0.23 9.4 0.0 1.2 1 0 0 1 1 1 0 Orbivirus VP4 core protein Clat_adaptor_s PF01217.20 KLO13873.1 - 4.4e-56 188.8 2.6 4.9e-56 188.6 2.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 KLO13873.1 - 0.015 14.9 0.1 0.018 14.7 0.1 1.1 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Pkinase PF00069.25 KLO13874.1 - 5.4e-06 26.0 0.0 9.5e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13874.1 - 1.1e-05 24.9 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO13875.1 - 8.9e-40 136.7 0.0 1.2e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13875.1 - 1.2e-35 123.1 0.0 1.5e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO13875.1 - 6.5e-06 25.2 0.0 9.6e-06 24.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KLO13875.1 - 0.00093 18.8 0.1 0.0074 15.9 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 KLO13875.1 - 0.0039 16.6 0.1 0.012 15.0 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO13875.1 - 0.049 13.0 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO13875.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KLO13876.1 - 8.1e-40 136.8 0.0 1e-39 136.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13876.1 - 1.2e-37 129.6 0.0 1.4e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO13876.1 - 1.5e-05 24.5 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO13876.1 - 0.00027 19.9 0.0 0.00037 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO13876.1 - 0.0054 16.7 0.0 0.0097 15.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO13876.1 - 0.0067 16.0 0.0 0.027 14.1 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 KLO13876.1 - 0.021 13.8 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KLO13876.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KLO13879.1 - 1.4e-42 145.9 0.0 1.9e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13879.1 - 7.2e-41 140.2 0.0 1e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO13879.1 - 8.6e-06 24.8 0.0 1.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO13879.1 - 0.0058 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO13879.1 - 0.02 14.5 0.0 0.095 12.3 0.0 1.9 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KLO13879.1 - 0.079 12.9 0.0 0.23 11.4 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KLO13879.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KLO13881.1 - 1.9e-42 145.5 0.0 2.4e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13881.1 - 2e-39 135.5 0.0 2.6e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO13881.1 - 6.1e-06 25.3 0.1 8.6e-06 24.8 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KLO13881.1 - 0.0082 15.8 0.0 0.069 12.7 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 KLO13881.1 - 0.019 14.3 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KLO13881.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO13881.1 - 0.031 14.2 0.0 0.1 12.5 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KLO13882.1 - 2.8e-73 246.5 0.0 1.5e-39 136.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13882.1 - 2.6e-69 233.4 0.2 1.4e-35 122.8 0.2 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KLO13882.1 - 8.4e-06 25.3 0.3 0.091 12.1 0.0 2.7 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KLO13882.1 - 0.00012 21.0 0.0 0.12 11.2 0.1 2.2 2 0 0 2 2 2 2 Fungal protein kinase RIO1 PF01163.22 KLO13882.1 - 0.00084 19.0 0.0 0.047 13.3 0.0 2.5 2 1 0 2 2 2 1 RIO1 family Kdo PF06293.14 KLO13882.1 - 0.035 13.5 0.0 0.95 8.8 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KLO13883.1 - 1.9e-12 47.1 0.0 2.6e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13883.1 - 1e-09 38.1 0.0 1.2e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO13888.1 - 3.1e-42 144.8 0.0 4.2e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13888.1 - 2e-40 138.7 0.0 2.7e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO13888.1 - 9e-05 21.4 0.1 0.00015 20.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO13888.1 - 0.0026 17.1 0.0 0.0088 15.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like FrhB_FdhB_N PF04422.13 KLO13888.1 - 0.035 14.2 0.0 0.082 13.1 0.0 1.5 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Kdo PF06293.14 KLO13888.1 - 0.041 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO13888.1 - 0.055 13.1 1.2 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family DUF3873 PF12989.7 KLO13889.1 - 1 9.8 4.2 16 6.0 2.4 2.7 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) Pkinase PF00069.25 KLO13891.1 - 8.2e-42 143.4 0.0 1.2e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13891.1 - 3.3e-39 134.7 0.0 4.3e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO13891.1 - 6.9e-05 21.8 0.1 0.00011 21.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO13891.1 - 0.0053 16.1 0.0 0.012 15.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO13891.1 - 0.034 13.7 1.3 0.11 12.0 0.1 2.0 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KLO13891.1 - 0.047 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FrhB_FdhB_N PF04422.13 KLO13891.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Helicase_C PF00271.31 KLO13891.1 - 0.15 12.4 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Pkinase_Tyr PF07714.17 KLO13898.1 - 3.1e-68 229.9 0.0 6e-35 120.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KLO13898.1 - 9.6e-66 221.8 0.0 6.5e-39 133.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KLO13898.1 - 3.2e-06 26.7 0.1 0.057 12.7 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 KLO13898.1 - 0.0091 15.4 0.1 0.051 12.9 0.0 2.1 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KLO13898.1 - 0.015 14.1 0.0 0.048 12.4 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 KLO13898.1 - 0.043 13.4 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KLO13898.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KLO13900.1 - 1.6e-69 234.2 0.0 1.6e-40 139.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13900.1 - 1.1e-65 221.6 0.4 3e-36 125.0 0.1 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KLO13900.1 - 9e-08 31.8 0.1 0.00075 18.9 0.0 2.8 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KLO13900.1 - 0.014 14.2 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KLO13900.1 - 0.016 14.5 0.0 0.53 9.6 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO13900.1 - 0.02 14.5 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KLO13900.1 - 0.023 14.6 0.1 0.074 13.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Aldolase_II PF00596.21 KLO13901.1 - 5e-46 157.0 0.0 6.1e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Pkinase PF00069.25 KLO13904.1 - 1e-10 41.5 0.0 1.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13904.1 - 1.5e-08 34.3 0.0 2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO13905.1 - 1.5e-33 116.3 0.0 1.8e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13905.1 - 4.5e-31 108.1 0.0 5.7e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO13905.1 - 5e-06 26.0 0.0 7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO13905.1 - 0.0029 17.0 0.0 0.0038 16.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO13905.1 - 0.011 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KLO13905.1 - 0.031 14.2 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO13905.1 - 0.041 12.7 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Methyltransf_2 PF00891.18 KLO13906.1 - 1.5e-22 80.0 0.1 3.9e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Dimerisation PF08100.11 KLO13906.1 - 0.0002 21.3 0.1 0.00045 20.2 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain MTS PF05175.14 KLO13906.1 - 0.00041 19.9 0.0 0.00088 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KLO13906.1 - 0.0098 16.6 0.0 0.024 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KLO13906.1 - 0.023 14.2 0.0 0.055 13.0 0.0 1.5 2 0 0 2 2 2 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 KLO13906.1 - 0.06 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KLO13906.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KLO13906.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CCDC158 PF15921.5 KLO13907.1 - 0.04 11.8 0.1 0.052 11.4 0.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 Pkinase PF00069.25 KLO13908.1 - 1.6e-28 99.8 0.0 1.8e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13908.1 - 8.6e-27 94.0 0.0 9.3e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO13908.1 - 0.00027 20.4 0.0 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO13908.1 - 0.0038 16.1 0.0 0.0047 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO13908.1 - 0.0091 15.4 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO13908.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KLO13908.1 - 0.077 12.9 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DDE_1 PF03184.19 KLO13910.1 - 5.1e-08 32.8 0.0 2.1e-07 30.8 0.0 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease Pkinase_Tyr PF07714.17 KLO13914.1 - 1.4e-30 106.4 0.1 1.7e-30 106.2 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO13914.1 - 2.5e-30 105.7 0.1 2.9e-30 105.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO13914.1 - 0.0022 17.4 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO13914.1 - 0.0036 17.3 0.0 0.0046 16.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO13914.1 - 0.012 14.4 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KLO13914.1 - 0.031 13.9 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KLO13914.1 - 0.17 11.4 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Methyltransf_2 PF00891.18 KLO13915.1 - 8.2e-24 84.1 0.1 1.8e-20 73.2 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain MTS PF05175.14 KLO13915.1 - 0.00028 20.5 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KLO13915.1 - 0.0025 18.5 0.0 0.0056 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.11 KLO13915.1 - 0.0042 17.1 0.1 0.0094 15.9 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.12 KLO13915.1 - 0.038 14.7 0.0 0.087 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KLO13915.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 KLO13917.1 - 1.3e-28 100.2 0.0 1.5e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO13917.1 - 8.1e-26 90.9 0.0 9.8e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO13917.1 - 0.038 12.8 0.0 0.047 12.5 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KLO13917.1 - 0.048 12.6 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KLO13917.1 - 0.05 13.0 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO13917.1 - 0.083 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO13917.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KLO13917.1 - 0.25 10.9 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF1679 PF07914.11 KLO13917.1 - 0.29 9.9 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Clat_adaptor_s PF01217.20 KLO13919.1 - 7.8e-57 191.2 3.2 8.6e-57 191.1 3.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 KLO13919.1 - 0.048 13.2 0.1 0.057 13.0 0.1 1.1 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Mpv17_PMP22 PF04117.12 KLO13920.1 - 8e-09 35.6 0.3 1.7e-08 34.6 0.3 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family NRDE-2 PF08424.10 KLO13922.1 - 1.7e-64 218.0 0.4 1.1e-63 215.3 0.4 2.2 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 KLO13922.1 - 0.00015 22.3 0.1 0.0023 18.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 KLO13922.1 - 0.00031 20.0 0.1 0.0028 16.9 0.1 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KLO13922.1 - 0.00036 21.1 5.5 0.028 15.2 0.0 5.7 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KLO13922.1 - 0.0033 17.9 0.0 0.43 11.1 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KLO13922.1 - 0.012 15.9 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KLO13922.1 - 0.018 15.1 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO13922.1 - 0.24 10.7 0.0 2.8 7.2 0.0 2.1 1 1 0 2 2 2 0 MalT-like TPR region UPF0113_N PF17833.1 KLO13923.1 - 3.5e-30 104.4 0.0 5.3e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KLO13923.1 - 1.2e-26 92.7 0.0 3.3e-26 91.4 0.0 1.7 2 0 0 2 2 2 1 UPF0113 PUA domain MFS_1 PF07690.16 KLO13925.1 - 3.6e-32 111.7 31.2 3.6e-32 111.7 31.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KLO13925.1 - 0.00045 19.8 5.9 0.0011 18.5 3.0 2.1 2 0 0 2 2 2 1 Nodulin-like MASE2 PF05230.11 KLO13925.1 - 5.7 7.1 8.7 0.21 11.7 0.4 2.9 3 1 1 4 4 4 0 MASE2 domain MFS_1 PF07690.16 KLO13926.1 - 6.7e-29 100.9 24.4 6.7e-29 100.9 24.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M41 PF01434.18 KLO13927.1 - 3.2e-63 213.0 0.0 5.1e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KLO13927.1 - 1.1e-42 145.6 0.0 2.2e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KLO13927.1 - 4.9e-13 48.7 0.1 1.6e-12 47.0 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KLO13927.1 - 1.9e-12 47.5 0.0 4.4e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 KLO13927.1 - 0.0045 17.4 0.1 0.12 12.8 0.1 2.8 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KLO13927.1 - 0.0052 16.0 0.0 0.0092 15.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KLO13927.1 - 0.012 15.6 0.0 0.049 13.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KLO13927.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KLO13927.1 - 0.014 15.7 0.0 0.47 10.7 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.14 KLO13927.1 - 0.038 14.1 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KLO13927.1 - 0.083 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 KLO13927.1 - 0.086 13.3 0.6 0.24 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KLO13927.1 - 0.19 11.1 0.1 0.44 9.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DSPc PF00782.20 KLO13928.1 - 1.9e-19 69.8 0.0 5.9e-17 61.7 0.0 3.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KLO13928.1 - 0.0048 16.5 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KLO13928.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF846 PF05832.12 KLO13929.1 - 5.2e-54 182.1 8.6 6.7e-54 181.7 8.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Nucleoside_tran PF01733.18 KLO13929.1 - 0.016 14.6 2.5 0.49 9.7 0.9 2.0 2 0 0 2 2 2 0 Nucleoside transporter DUF2207 PF09972.9 KLO13929.1 - 0.12 11.2 1.2 3.1 6.5 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SPRY PF00622.28 KLO13930.1 - 1.2e-18 67.3 0.0 2.2e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain CBS PF00571.28 KLO13931.1 - 2.6e-20 72.6 3.7 1e-09 38.7 0.0 4.5 4 0 0 4 4 4 4 CBS domain DUF1195 PF06708.11 KLO13931.1 - 0.048 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Methyltransf_23 PF13489.6 KLO13932.1 - 1.1e-07 31.8 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Polyketide_cyc2 PF10604.9 KLO13932.1 - 1.6e-06 28.4 0.1 2.9e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_25 PF13649.6 KLO13932.1 - 0.017 15.9 0.0 0.1 13.3 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KLO13932.1 - 0.03 15.0 0.0 0.084 13.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PX PF00787.24 KLO13933.1 - 7.1e-16 58.2 0.0 1.2e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 PX domain SurA_N PF09312.11 KLO13933.1 - 0.02 15.0 1.4 0.048 13.7 1.4 1.6 1 0 0 1 1 1 0 SurA N-terminal domain Nmad5 PF18757.1 KLO13933.1 - 0.12 12.6 0.0 9.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 SlyX PF04102.12 KLO13933.1 - 4.2 8.1 9.9 30 5.3 0.1 3.6 2 1 1 3 3 3 0 SlyX Rhodanese PF00581.20 KLO13935.1 - 5.1e-15 55.9 0.0 8.3e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Multi_ubiq PF14452.6 KLO13935.1 - 0.072 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Multiubiquitin Ctr PF04145.15 KLO13936.1 - 3.5e-26 92.6 0.0 4.1e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family GNAT_like PF18407.1 KLO13936.1 - 0.076 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyltransferase like domain Podoplanin PF05808.11 KLO13937.1 - 0.0024 18.0 0.1 0.0037 17.4 0.1 1.2 1 0 0 1 1 1 1 Podoplanin Frataxin_Cyay PF01491.16 KLO13939.1 - 1.3e-35 121.7 0.0 1.6e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain FAM91_C PF14648.6 KLO13939.1 - 0.18 10.6 0.1 0.25 10.1 0.1 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Bromodomain PF00439.25 KLO13940.1 - 7.2e-34 115.7 0.1 2e-17 63.0 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KLO13940.1 - 5.9e-19 68.0 1.6 1.3e-18 67.0 0.8 2.0 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation WD40 PF00400.32 KLO13940.1 - 3e-17 62.7 7.9 0.00021 22.0 0.2 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KLO13940.1 - 0.0001 21.4 0.2 0.0016 17.5 0.0 2.4 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KLO13940.1 - 0.0014 18.9 0.0 2.1 8.7 0.0 4.7 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain FlxA PF14282.6 KLO13940.1 - 0.0074 16.3 5.3 0.025 14.6 5.3 1.9 1 0 0 1 1 1 1 FlxA-like protein V_ATPase_I PF01496.19 KLO13940.1 - 0.09 10.7 1.8 0.14 10.0 1.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ku_C PF03730.14 KLO13940.1 - 0.35 11.6 10.0 24 5.7 10.5 3.5 3 0 0 3 3 3 0 Ku70/Ku80 C-terminal arm Hid1 PF12722.7 KLO13940.1 - 1.3 7.1 5.1 2.1 6.4 5.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 KLO13940.1 - 3.7 5.7 9.0 8.4 4.5 9.0 1.5 1 0 0 1 1 1 0 CDC45-like protein PWI PF01480.17 KLO13941.1 - 2.2e-09 37.5 0.0 4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KLO13941.1 - 1.7e-05 24.6 2.7 2.9e-05 23.9 2.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KLO13941.1 - 0.00045 20.2 5.7 0.00078 19.4 5.7 1.4 1 0 0 1 1 1 1 Zinc finger domain RRM_3 PF08777.11 KLO13941.1 - 0.054 13.5 0.0 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Torus PF16131.5 KLO13941.1 - 0.055 14.2 0.5 0.15 12.8 0.5 1.7 1 0 0 1 1 1 0 Torus domain Nup35_RRM_2 PF14605.6 KLO13941.1 - 0.089 12.8 0.0 5.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 KLO13941.1 - 0.4 10.5 3.4 0.76 9.7 3.4 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger DUF4407 PF14362.6 KLO13941.1 - 3 7.1 4.6 4.8 6.5 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dynamitin PF04912.14 KLO13941.1 - 9.7 5.4 9.0 5.1 6.3 0.2 2.2 1 1 1 2 2 2 0 Dynamitin Sel1 PF08238.12 KLO13942.1 - 7.5e-18 64.6 7.7 2.8e-05 24.6 0.8 3.6 3 0 0 3 3 3 3 Sel1 repeat TPR_2 PF07719.17 KLO13942.1 - 0.00061 19.7 7.1 0.041 14.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KLO13942.1 - 0.0074 16.1 1.7 0.066 13.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KLO13942.1 - 0.022 15.6 2.2 38 5.5 0.3 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KLO13942.1 - 0.056 13.7 8.0 0.18 12.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KLO13942.1 - 0.093 12.6 1.5 7.9 6.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KLO13942.1 - 0.24 12.1 5.1 2.7 8.7 0.6 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Helicase_C PF00271.31 KLO13943.1 - 1.4e-20 73.6 0.1 3.9e-20 72.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO13943.1 - 1.1e-19 71.0 0.1 7.4e-19 68.4 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KLO13943.1 - 6.5e-15 55.3 0.0 1.5e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KLO13943.1 - 0.15 12.3 0.0 0.9 9.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain HUN PF08729.10 KLO13943.1 - 1.1 9.3 5.3 4.9 7.2 5.3 2.2 1 0 0 1 1 1 0 HPC2 and ubinuclein domain FYRN PF05964.14 KLO13945.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 F/Y-rich N-terminus G-patch PF01585.23 KLO13946.1 - 9e-11 41.5 0.1 1.8e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 KLO13946.1 - 1e-06 28.8 5.9 2.9e-06 27.4 6.0 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KLO13946.1 - 8e-05 22.9 1.5 0.00018 21.8 1.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.7 KLO13946.1 - 0.00014 21.9 0.0 0.00037 20.5 0.0 1.7 1 0 0 1 1 1 1 G-patch domain DUF4820 PF16091.5 KLO13946.1 - 0.0041 16.5 3.8 0.0061 16.0 3.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) zf-C2H2_2 PF12756.7 KLO13946.1 - 0.013 15.8 0.7 0.024 15.0 0.7 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 KLO13946.1 - 0.038 14.2 0.8 0.063 13.4 0.3 1.5 2 0 0 2 2 2 0 Aberrant zinc-finger bZIP_2 PF07716.15 KLO13948.1 - 5.3e-07 29.6 13.1 5.3e-07 29.6 13.1 5.4 5 1 1 6 6 6 1 Basic region leucine zipper bZIP_1 PF00170.21 KLO13948.1 - 6.9e-07 29.3 10.1 6.9e-07 29.3 10.1 4.9 5 2 0 5 5 5 1 bZIP transcription factor bZIP_Maf PF03131.17 KLO13948.1 - 0.03 14.9 8.7 0.03 14.9 8.7 5.4 3 1 2 5 5 5 0 bZIP Maf transcription factor RIC3 PF15361.6 KLO13948.1 - 0.33 11.3 0.1 0.33 11.3 0.1 3.5 3 1 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 Sec34 PF04136.15 KLO13948.1 - 0.65 9.9 9.9 0.18 11.7 2.1 2.7 2 0 0 2 2 2 0 Sec34-like family CALCOCO1 PF07888.11 KLO13948.1 - 3.2 6.5 57.0 0.33 9.7 8.5 3.1 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like PXA PF02194.15 KLO13949.1 - 2.2e-44 151.6 0.1 3.4e-44 151.0 0.1 1.3 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KLO13949.1 - 0.089 13.4 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Sorting nexin C terminal Glucosamine_iso PF01182.20 KLO13951.1 - 2.3e-70 237.0 0.0 3e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase THAP PF05485.12 KLO13951.1 - 0.079 13.9 0.4 0.56 11.2 0.2 2.3 2 1 0 2 2 2 0 THAP domain Peptidase_M28 PF04389.17 KLO13952.1 - 6e-33 114.2 0.0 8.7e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Aminotran_4 PF01063.19 KLO13953.1 - 3.2e-31 108.9 0.0 3.9e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Ras PF00071.22 KLO13954.1 - 7.5e-59 198.0 0.4 8.7e-59 197.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO13954.1 - 1.9e-33 115.2 0.0 3.2e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO13954.1 - 1.1e-15 57.6 0.1 1.2e-15 57.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KLO13954.1 - 2.2e-08 34.2 0.0 4.6e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KLO13954.1 - 1.6e-07 31.0 0.1 1.9e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KLO13954.1 - 4e-07 29.8 0.1 5.8e-06 26.0 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KLO13954.1 - 3e-05 24.0 0.3 0.0022 17.9 0.1 2.3 1 1 1 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 KLO13954.1 - 0.0003 20.5 0.2 0.099 12.4 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KLO13954.1 - 0.00031 20.6 0.4 0.014 15.2 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KLO13954.1 - 0.00039 19.9 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 KLO13954.1 - 0.00042 19.7 1.0 0.013 14.8 0.1 2.4 2 1 0 2 2 2 1 Septin cobW PF02492.19 KLO13954.1 - 0.004 16.7 0.0 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KLO13954.1 - 0.006 16.9 0.0 0.015 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO13954.1 - 0.0071 16.8 0.1 0.013 15.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KLO13954.1 - 0.0099 15.4 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 KLO13954.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KLO13954.1 - 0.023 14.6 0.2 0.048 13.6 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MCM PF00493.23 KLO13954.1 - 0.037 13.1 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Glyco_hydro_75 PF07335.11 KLO13954.1 - 0.048 13.9 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 AAA_5 PF07728.14 KLO13954.1 - 0.059 13.4 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 KLO13954.1 - 0.066 12.7 0.0 0.7 9.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B NB-ARC PF00931.22 KLO13954.1 - 0.076 12.2 0.5 0.11 11.7 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 KLO13954.1 - 0.081 12.8 0.1 0.14 12.0 0.0 1.5 2 0 0 2 2 1 0 NTPase NACHT PF05729.12 KLO13954.1 - 0.09 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 KLO13954.1 - 0.095 12.1 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 KLO13954.1 - 0.11 13.1 1.2 0.25 11.8 1.2 1.9 1 1 0 1 1 1 0 ABC transporter DAP3 PF10236.9 KLO13954.1 - 0.11 11.7 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 G-alpha PF00503.20 KLO13954.1 - 0.18 10.9 2.3 0.84 8.7 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit ATG16 PF08614.11 KLO13955.1 - 2.8e-50 171.4 19.4 4.3e-50 170.7 19.4 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 KLO13955.1 - 0.00083 19.6 22.4 0.079 13.2 9.8 3.1 2 1 1 3 3 3 2 TATA element modulatory factor 1 TATA binding DUF16 PF01519.16 KLO13955.1 - 0.023 15.2 3.4 0.065 13.7 3.4 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF16 EzrA PF06160.12 KLO13955.1 - 0.053 11.7 15.5 0.37 8.9 12.1 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF4570 PF15134.6 KLO13955.1 - 0.071 13.1 0.2 0.071 13.1 0.2 2.8 1 1 1 3 3 2 0 Domain of unknown function (DUF4570) Spc7 PF08317.11 KLO13955.1 - 0.16 10.8 17.5 0.015 14.2 12.1 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein MPS2 PF17060.5 KLO13955.1 - 0.19 11.0 8.4 0.76 9.0 8.0 2.0 1 1 0 1 1 1 0 Monopolar spindle protein 2 PilW PF16074.5 KLO13955.1 - 0.21 11.6 3.8 0.15 12.1 1.3 2.1 2 2 0 2 2 2 0 Type IV Pilus-assembly protein W Flagellar_rod PF05149.12 KLO13955.1 - 0.52 9.7 14.0 0.16 11.4 10.8 1.8 2 0 0 2 2 2 0 Paraflagellar rod protein DUF4407 PF14362.6 KLO13955.1 - 1.3 8.3 13.0 0.6 9.4 9.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 KLO13955.1 - 1.7 9.2 11.9 7.9 7.1 5.1 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 KLO13955.1 - 2.4 8.2 5.2 6.3 6.9 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 KLO13955.1 - 2.5 8.6 22.0 2.4 8.6 3.9 4.1 2 1 1 3 3 3 0 Cell division protein ZapB Fib_alpha PF08702.10 KLO13955.1 - 3 8.0 9.4 3.1 8.0 7.4 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SOGA PF11365.8 KLO13955.1 - 3.1 9.0 14.9 0.27 12.4 4.6 3.1 2 1 0 3 3 3 0 Protein SOGA zf-C4H2 PF10146.9 KLO13955.1 - 3.2 8.0 10.8 3.2 8.0 8.5 2.1 2 1 0 2 2 2 0 Zinc finger-containing protein YabA PF06156.13 KLO13955.1 - 4.1 8.1 16.2 0.68 10.6 2.9 3.2 2 1 1 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 KLO13955.1 - 5.2 7.5 17.3 1.9 8.9 10.1 2.4 1 1 1 2 2 2 0 Fez1 V_ATPase_I PF01496.19 KLO13955.1 - 7.5 4.3 8.5 11 3.8 8.4 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.22 KLO13955.1 - 9.4 6.5 15.4 4.4 7.6 7.9 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ALMT PF11744.8 KLO13955.1 - 9.6 4.9 7.5 13 4.5 7.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RRM_1 PF00076.22 KLO13956.1 - 3.8e-55 183.6 0.0 1.2e-19 69.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KLO13956.1 - 8.6e-10 38.3 0.0 0.00027 20.5 0.0 3.2 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KLO13956.1 - 8.7e-06 25.5 0.0 0.0031 17.3 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KLO13956.1 - 7.2e-05 22.8 0.0 0.015 15.4 0.0 3.4 3 1 0 3 3 3 1 RNA recognition motif Cas_Cas2CT1978 PF09707.10 KLO13956.1 - 0.00037 20.5 0.0 0.57 10.3 0.0 3.0 3 0 0 3 3 3 2 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM_2 PF14605.6 KLO13956.1 - 0.00066 19.6 0.1 5.6 7.0 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Band_7 PF01145.25 KLO13957.1 - 1.9e-23 83.4 4.6 2.7e-23 82.9 3.9 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KLO13957.1 - 0.00025 20.2 4.9 0.00032 19.9 4.9 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF1191 PF06697.12 KLO13957.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) MT0933_antitox PF14013.6 KLO13957.1 - 9.7 6.6 8.1 6.3 7.2 0.7 2.3 1 1 0 2 2 2 0 MT0933-like antitoxin protein Glyco_hydro_3_C PF01915.22 KLO13958.1 - 9.5e-56 189.0 0.0 2.2e-55 187.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KLO13958.1 - 1.2e-35 123.4 0.0 2.2e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KLO13958.1 - 4.2e-18 65.2 0.0 8.5e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.18 KLO13958.1 - 2.1e-11 43.6 7.3 5e-11 42.4 7.3 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain MSP1_C PF07462.11 KLO13958.1 - 3.3 6.3 7.4 5 5.7 7.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Oxysterol_BP PF01237.18 KLO13959.1 - 1.1e-110 370.0 0.0 3.8e-110 368.2 0.0 1.8 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KLO13959.1 - 1.6e-19 70.0 0.2 4.2e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KLO13959.1 - 8.3e-08 32.7 0.0 1.9e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Sec1 PF00995.23 KLO13960.1 - 8.8e-125 418.1 0.0 1.1e-124 417.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Qua1 PF16274.5 KLO13960.1 - 0.059 13.2 0.7 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Qua1 domain MFS_1 PF07690.16 KLO13961.1 - 1.2e-22 80.3 20.6 4.2e-22 78.5 19.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Vta1 PF04652.16 KLO13962.1 - 9.9e-46 155.3 2.4 1.3e-45 154.9 2.4 1.2 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KLO13962.1 - 2.6e-16 59.0 0.6 4.2e-16 58.3 0.0 1.7 2 0 0 2 2 2 1 Vta1 C-terminal domain RSN1_7TM PF02714.15 KLO13963.1 - 2.9e-19 69.5 20.4 5.9e-19 68.4 20.4 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KLO13963.1 - 1.5e-06 28.0 0.7 1.5e-06 28.0 0.7 3.2 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 KLO13963.1 - 0.0034 17.5 0.1 0.012 15.8 0.0 1.9 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF2615 PF11027.8 KLO13963.1 - 0.33 11.1 4.2 1.4 9.1 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2615) Septin PF00735.18 KLO13965.1 - 2.7e-108 361.5 0.0 4.5e-108 360.8 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KLO13965.1 - 3.7e-07 30.2 0.1 1e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO13965.1 - 0.0029 17.5 0.8 0.034 14.1 0.6 2.7 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KLO13965.1 - 0.0031 17.1 0.3 0.092 12.3 0.1 2.6 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KLO13965.1 - 0.0038 16.6 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KLO13965.1 - 0.0045 17.1 3.4 0.57 10.2 0.0 3.0 2 1 1 3 3 3 2 Dynamin family FtsK_SpoIIIE PF01580.18 KLO13965.1 - 0.038 13.3 0.2 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family IIGP PF05049.13 KLO13965.1 - 0.051 12.6 0.6 0.099 11.7 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 KLO13965.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MutS_V PF00488.21 KLO13966.1 - 1.3e-70 237.3 0.1 2.6e-70 236.3 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KLO13966.1 - 5e-36 124.7 3.5 7.5e-36 124.1 0.8 2.6 3 1 0 3 3 3 1 MutS domain III MutS_I PF01624.20 KLO13966.1 - 4e-20 72.1 0.0 1.1e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KLO13966.1 - 1.1e-10 42.0 0.1 2.6e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 KLO13966.1 - 2.2e-05 24.1 0.0 5.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain MutS_IV PF05190.18 KLO13966.1 - 0.0028 18.0 0.0 0.0071 16.7 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 KLO13966.1 - 0.0063 17.0 0.7 0.044 14.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KLO13966.1 - 0.058 13.4 0.0 0.21 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KLO13966.1 - 0.079 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aconitase PF00330.20 KLO13967.1 - 5.3e-150 500.4 0.0 6.6e-150 500.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KLO13967.1 - 3e-34 118.1 0.0 5.3e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KLO13967.1 - 0.14 10.9 0.0 0.63 8.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF521) Asn_synthase PF00733.21 KLO13968.1 - 3e-20 73.2 4.0 2.5e-16 60.3 4.0 3.0 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KLO13968.1 - 2.6e-05 24.1 0.0 5.7e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase domain 6PGD PF00393.19 KLO13969.1 - 8.5e-125 415.9 0.0 1e-124 415.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KLO13969.1 - 1.1e-49 168.6 0.0 1.6e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KLO13969.1 - 0.00021 21.8 0.1 0.00049 20.6 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent CoatB PF10389.9 KLO13969.1 - 0.023 14.5 1.5 5.4 6.9 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage coat protein B ApbA PF02558.16 KLO13969.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glycophorin_A PF01102.18 KLO13970.1 - 0.0022 18.2 0.0 0.007 16.6 0.0 1.8 1 0 0 1 1 1 1 Glycophorin A Alpha_GJ PF03229.13 KLO13970.1 - 0.0043 17.6 1.0 0.0043 17.6 1.0 1.9 2 0 0 2 2 2 1 Alphavirus glycoprotein J Amnionless PF14828.6 KLO13970.1 - 0.0043 15.9 0.1 0.0077 15.1 0.1 1.3 1 0 0 1 1 1 1 Amnionless Podoplanin PF05808.11 KLO13970.1 - 0.017 15.2 0.7 0.039 14.1 0.7 1.6 1 0 0 1 1 1 0 Podoplanin DUF4690 PF15756.5 KLO13970.1 - 0.027 15.1 0.3 0.027 15.1 0.3 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage EphA2_TM PF14575.6 KLO13970.1 - 0.049 14.5 0.0 0.12 13.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5305 PF17231.2 KLO13970.1 - 0.26 10.7 0.0 1.4 8.2 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Gram_pos_anchor PF00746.21 KLO13970.1 - 0.3 11.1 2.7 0.59 10.1 2.7 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Syndecan PF01034.20 KLO13970.1 - 0.47 10.4 0.8 0.86 9.6 0.8 1.3 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 KLO13971.1 - 5.6e-05 23.1 0.8 0.00016 21.6 0.8 1.8 1 0 0 1 1 1 1 TMEM154 protein family Glycophorin_A PF01102.18 KLO13971.1 - 0.00011 22.4 0.4 0.00011 22.4 0.4 1.9 2 0 0 2 2 2 1 Glycophorin A SKG6 PF08693.10 KLO13971.1 - 0.00062 19.1 5.4 0.0011 18.3 5.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 KLO13971.1 - 0.00074 19.4 2.0 0.0015 18.4 2.0 1.4 1 0 0 1 1 1 1 Syndecan domain Mid2 PF04478.12 KLO13971.1 - 0.00092 19.1 0.1 0.0024 17.7 0.1 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Podoplanin PF05808.11 KLO13971.1 - 0.001 19.2 3.5 0.0024 18.0 3.5 1.6 1 0 0 1 1 1 1 Podoplanin Amnionless PF14828.6 KLO13971.1 - 0.0013 17.7 0.2 0.0018 17.2 0.2 1.1 1 0 0 1 1 1 1 Amnionless DUF5305 PF17231.2 KLO13971.1 - 0.0013 18.2 0.4 0.0023 17.4 0.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Orf78 PF06024.12 KLO13971.1 - 0.0024 18.1 0.0 0.0045 17.3 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) RIFIN PF02009.16 KLO13971.1 - 0.0044 17.0 0.0 0.006 16.5 0.0 1.1 1 0 0 1 1 1 1 Rifin TMEM132D_C PF15706.5 KLO13971.1 - 0.0054 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM51 PF15345.6 KLO13971.1 - 0.0087 15.9 2.1 0.0087 15.9 2.1 1.7 1 1 1 2 2 2 1 Transmembrane protein 51 EphA2_TM PF14575.6 KLO13971.1 - 0.012 16.4 0.0 0.024 15.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rax2 PF12768.7 KLO13971.1 - 0.033 13.7 0.1 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4381 PF14316.6 KLO13971.1 - 0.034 14.4 0.0 0.066 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2207 PF09972.9 KLO13971.1 - 0.049 12.4 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) VEGFR-2_TMD PF17988.1 KLO13971.1 - 0.077 12.4 2.2 0.15 11.5 2.2 1.5 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Trp_oprn_chp PF09534.10 KLO13971.1 - 0.08 12.7 0.5 0.14 12.0 0.5 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Plasmodium_Vir PF05795.11 KLO13971.1 - 0.16 11.3 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Cadherin_C_2 PF16492.5 KLO13971.1 - 0.21 12.4 0.1 0.21 12.4 0.1 2.3 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Stevor PF17410.2 KLO13971.1 - 0.29 10.6 0.0 0.47 10.0 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Shisa PF13908.6 KLO13971.1 - 2.3 8.4 12.0 12 6.1 11.9 2.2 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Rax2 PF12768.7 KLO13972.1 - 0.0046 16.4 0.1 0.0098 15.4 0.1 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Herpes_gE PF02480.16 KLO13972.1 - 0.089 11.5 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.15 KLO13972.1 - 0.22 11.3 0.1 0.39 10.5 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RAP1 PF07218.11 KLO13972.1 - 1.1 7.4 4.1 2 6.6 4.1 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF5423 PF17461.2 KLO13973.1 - 0.002 17.0 0.1 0.0025 16.8 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5423) Yippee-Mis18 PF03226.14 KLO13973.1 - 0.13 12.5 0.6 1.7 8.9 1.0 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly WD40 PF00400.32 KLO13974.1 - 2.6e-44 148.3 10.2 1.3e-08 35.3 0.5 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KLO13974.1 - 1.7e-26 93.0 0.0 3e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KLO13974.1 - 2e-09 37.6 0.1 0.011 16.0 0.0 4.9 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KLO13974.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 LisH Nup160 PF11715.8 KLO13974.1 - 0.063 11.9 2.1 6.8 5.2 0.0 3.6 3 2 2 5 5 5 0 Nucleoporin Nup120/160 ELYS-bb PF16687.5 KLO13974.1 - 0.11 11.1 0.0 0.24 10.0 0.0 1.5 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin eIF2A PF08662.11 KLO13974.1 - 0.18 11.6 0.0 4.8 7.0 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A NAD_binding_6 PF08030.12 KLO13975.1 - 4.2e-24 85.5 0.0 7.4e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KLO13975.1 - 5.4e-22 78.0 0.0 1.1e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KLO13975.1 - 3.2e-18 66.0 10.0 3.2e-18 66.0 10.0 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KLO13975.1 - 0.00053 20.6 0.0 0.054 14.2 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Coatomer_b_Cpla PF14806.6 KLO13975.1 - 0.022 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform HORMA PF02301.18 KLO13976.1 - 2.5e-17 63.2 0.1 3.8e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 KLO13976.1 - 0.071 12.9 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial HORMA domain 2 Nucleoporin_N PF08801.11 KLO13977.1 - 3.2e-70 237.0 0.0 8.3e-70 235.7 0.0 1.6 2 0 0 2 2 2 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KLO13977.1 - 1.1e-32 113.5 1.1 1.9e-32 112.8 1.1 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Polysacc_lyase PF14099.6 KLO13978.1 - 0.029 14.2 0.2 0.17 11.7 0.0 2.1 2 1 0 3 3 3 0 Polysaccharide lyase RINGv PF12906.7 KLO13979.1 - 7.2e-13 48.4 3.4 1e-12 47.9 3.4 1.2 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KLO13979.1 - 0.0051 17.1 6.1 0.0086 16.4 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain DUF983 PF06170.12 KLO13979.1 - 0.043 14.2 4.4 1.1 9.7 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF983) PHD PF00628.29 KLO13979.1 - 0.17 11.8 3.6 0.3 11.0 3.6 1.4 1 0 0 1 1 1 0 PHD-finger LisH_TPL PF17814.1 KLO13979.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 LisH-like dimerisation domain Mito_carr PF00153.27 KLO13980.1 - 1.8e-48 162.4 3.5 9.2e-17 60.8 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cohesin_load PF10345.9 KLO13982.1 - 0.1 11.0 0.1 1.9 6.8 0.3 2.1 1 1 1 2 2 2 0 Cohesin loading factor Aldo_ket_red PF00248.21 KLO13983.1 - 2.9e-67 226.9 0.0 3.9e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Sulfate_transp PF00916.20 KLO13987.1 - 4.9e-85 285.6 14.7 6.5e-85 285.2 14.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KLO13987.1 - 1e-17 63.8 0.0 1.9e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KLO13987.1 - 5.3e-05 23.5 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 STAS domain AMP-binding PF00501.28 KLO13988.1 - 8.1e-40 136.7 0.0 1.2e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KLO13988.1 - 9.6e-34 116.7 0.0 1.5e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KLO13988.1 - 3.5e-06 26.7 0.0 1.7e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KLO13988.1 - 0.00062 20.1 0.0 0.0016 18.8 0.0 1.8 1 1 0 1 1 1 1 Phosphopantetheine attachment site bZIP_1 PF00170.21 KLO13989.1 - 1.4e-07 31.5 5.6 2.7e-07 30.6 5.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KLO13989.1 - 6.8e-07 29.3 7.0 3.1e-05 23.9 2.6 2.5 1 1 1 2 2 2 2 Basic region leucine zipper zf-RING_UBOX PF13445.6 KLO13990.1 - 1.5e-05 24.9 2.8 0.0027 17.7 0.0 2.3 2 0 0 2 2 2 2 RING-type zinc-finger zf-Nse PF11789.8 KLO13990.1 - 0.00022 21.0 1.2 0.00053 19.7 1.1 1.7 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KLO13990.1 - 0.0026 17.9 0.0 0.0072 16.5 0.0 1.7 1 1 0 1 1 1 1 U-box domain UPF0547 PF10571.9 KLO13990.1 - 0.0027 17.7 1.8 0.03 14.4 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 zf-C3HC4_2 PF13923.6 KLO13990.1 - 0.0069 16.2 4.7 0.018 14.8 0.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 KLO13990.1 - 0.0093 15.7 2.1 0.018 14.8 2.1 1.5 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_2 PF13639.6 KLO13990.1 - 0.012 15.9 3.3 0.014 15.7 2.2 1.7 1 1 0 1 1 1 0 Ring finger domain DUF3584 PF12128.8 KLO13990.1 - 0.088 10.3 1.6 0.11 10.0 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rtf2 PF04641.12 KLO13990.1 - 0.093 12.1 2.3 0.089 12.1 0.9 1.5 1 1 1 2 2 2 0 Rtf2 RING-finger Ndc80_HEC PF03801.13 KLO13990.1 - 0.18 11.4 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family Prok-RING_4 PF14447.6 KLO13990.1 - 0.63 9.9 3.9 3 7.8 4.1 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KLO13990.1 - 3.4 7.6 6.8 14 5.6 0.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SseC PF04888.12 KLO13992.1 - 0.055 13.1 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF21 PF01595.20 KLO13992.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain COG5 PF10392.9 KLO13992.1 - 0.13 12.5 0.8 5.5 7.2 0.2 2.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 CHASE6_C PF17150.4 KLO13993.1 - 0.16 12.6 0.1 4.3 8.1 0.0 2.7 2 1 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain SseC PF04888.12 KLO13994.1 - 0.0085 15.7 3.8 0.0091 15.6 2.2 1.6 1 1 1 2 2 2 1 Secretion system effector C (SseC) like family IncD PF17628.2 KLO13994.1 - 0.021 14.6 0.1 0.033 14.0 0.1 1.2 1 0 0 1 1 1 0 Inclusion membrane protein D DUF2205 PF10224.9 KLO13994.1 - 0.05 13.6 0.4 0.14 12.2 0.4 1.6 1 0 0 1 1 1 0 Short coiled-coil protein IL32 PF15225.6 KLO13996.1 - 0.015 15.7 0.1 0.054 13.8 0.1 1.9 1 0 0 1 1 1 0 Interleukin 32 PPR_3 PF13812.6 KLO13996.1 - 0.029 14.4 0.1 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Pentatricopeptide repeat domain DUF4208 PF13907.6 KLO13996.1 - 0.033 14.6 0.1 0.15 12.5 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) BORCS8 PF10167.9 KLO13996.1 - 0.071 13.1 0.7 0.34 10.9 0.3 2.3 2 1 1 3 3 3 0 BLOC-1-related complex sub-unit 8 Tup_N PF08581.10 KLO13996.1 - 0.8 10.1 3.7 11 6.3 0.1 2.9 2 1 0 2 2 2 0 Tup N-terminal Aldo_ket_red PF00248.21 KLO13997.1 - 1.4e-76 257.6 0.0 1.5e-76 257.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RhoGEF PF00621.20 KLO13998.1 - 7.4e-13 49.1 0.0 1.6e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.22 KLO13998.1 - 4.4e-10 39.6 0.0 9.9e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 CNH domain p450 PF00067.22 KLO13999.1 - 1.1e-74 251.8 0.0 1.6e-74 251.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 IF4E PF01652.18 KLO14000.1 - 1.6e-53 180.8 0.0 2.2e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Aldedh PF00171.22 KLO14001.1 - 4.7e-114 381.4 0.2 6.1e-114 381.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KLO14001.1 - 0.0089 15.1 1.7 0.009 15.1 0.0 1.8 3 0 0 3 3 3 1 Acyl-CoA reductase (LuxC) Microvir_H PF04687.12 KLO14001.1 - 0.033 13.6 0.4 0.58 9.5 0.1 2.1 2 0 0 2 2 2 0 Microvirus H protein (pilot protein) DUF1487 PF07368.11 KLO14001.1 - 0.15 11.5 0.2 0.6 9.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Sin3a_C PF16879.5 KLO14002.1 - 5.8e-79 265.8 0.0 2.2e-76 257.3 0.0 3.7 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KLO14002.1 - 3.8e-41 139.1 0.0 8.1e-41 138.1 0.0 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 KLO14002.1 - 1.8e-34 117.6 6.8 5.6e-18 64.8 0.0 4.6 3 2 2 5 5 5 4 Paired amphipathic helix repeat S1-P1_nuclease PF02265.16 KLO14003.1 - 1.7e-48 165.7 0.0 1.6e-43 149.4 0.0 2.2 2 0 0 2 2 2 2 S1/P1 Nuclease PRiA4_ORF3 PF07929.11 KLO14004.1 - 0.003 17.3 1.5 0.004 16.9 0.1 1.9 2 1 0 2 2 2 1 Plasmid pRiA4b ORF-3-like protein NUP50 PF08911.11 KLO14004.1 - 0.53 11.0 4.3 1.1 10.0 1.3 2.7 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) YL1 PF05764.13 KLO14004.1 - 0.53 10.4 7.2 0.82 9.7 7.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein NmrA PF05368.13 KLO14005.1 - 3.3e-14 53.0 0.2 4.4e-14 52.6 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO14005.1 - 2.1e-06 27.8 0.2 2.9e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KLO14005.1 - 0.00047 20.4 0.1 0.001 19.4 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Creatinase_N_2 PF16189.5 KLO14007.1 - 6e-50 169.5 0.8 1.2e-47 162.0 0.1 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KLO14007.1 - 3.5e-48 164.1 0.0 5.1e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KLO14007.1 - 1.5e-27 96.8 0.1 1.9e-19 70.6 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KLO14007.1 - 3.8e-26 90.9 0.1 1.7e-25 88.9 0.1 2.2 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 DUF1335 PF07056.11 KLO14007.1 - 0.057 13.5 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1335) PIGA PF08288.12 KLO14008.1 - 1e-37 128.6 0.4 5.2e-37 126.3 0.3 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KLO14008.1 - 1.4e-27 96.8 3.3 1.4e-27 96.8 3.3 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KLO14008.1 - 1.5e-23 83.2 0.0 2.2e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KLO14008.1 - 2.3e-20 73.4 0.1 4.4e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KLO14008.1 - 3.7e-13 50.2 0.2 6.1e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KLO14008.1 - 2.2e-05 24.5 0.1 5.3e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KLO14008.1 - 0.0041 17.5 0.0 0.0079 16.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 AAA PF00004.29 KLO14009.1 - 9e-44 149.1 0.0 1.6e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KLO14009.1 - 7.8e-11 41.6 0.0 2e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KLO14009.1 - 2.4e-07 31.1 0.0 4.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 KLO14009.1 - 6.4e-07 29.2 0.1 1.4e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KLO14009.1 - 1.6e-06 28.2 0.0 7.2e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KLO14009.1 - 5.8e-06 26.8 0.1 7.5e-05 23.2 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KLO14009.1 - 4.1e-05 23.9 0.5 0.011 16.1 0.0 2.6 2 1 1 3 3 2 1 AAA domain RuvB_N PF05496.12 KLO14009.1 - 6.9e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KLO14009.1 - 0.00063 20.3 0.2 0.017 15.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 KLO14009.1 - 0.001 18.4 0.0 0.0021 17.3 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KLO14009.1 - 0.0014 18.8 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KLO14009.1 - 0.0017 18.1 0.1 0.0048 16.6 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 KLO14009.1 - 0.0039 16.7 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.11 KLO14009.1 - 0.0052 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KLO14009.1 - 0.0073 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KLO14009.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KLO14009.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KLO14009.1 - 0.018 14.4 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 KLO14009.1 - 0.022 14.5 0.1 0.096 12.4 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 KLO14009.1 - 0.024 13.8 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KLO14009.1 - 0.027 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KLO14009.1 - 0.029 14.1 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KLO14009.1 - 0.035 14.1 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KLO14009.1 - 0.039 14.3 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.9 KLO14009.1 - 0.041 14.1 0.1 0.081 13.2 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Parvo_NS1 PF01057.17 KLO14009.1 - 0.057 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KLO14009.1 - 0.06 12.9 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 KLO14009.1 - 0.086 12.1 0.0 0.2 10.9 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 KLO14009.1 - 0.1 12.4 0.2 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KLO14009.1 - 0.12 12.7 0.1 0.41 11.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 KLO14009.1 - 0.16 11.9 0.0 0.66 9.9 0.0 1.9 1 1 1 2 2 2 0 NACHT domain DivIC PF04977.15 KLO14009.1 - 0.66 9.8 3.3 0.4 10.5 0.7 1.9 2 0 0 2 2 2 0 Septum formation initiator G-alpha PF00503.20 KLO14011.1 - 4.6e-124 414.2 0.0 5.4e-124 413.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO14011.1 - 7.9e-09 35.2 0.1 4.8e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KLO14011.1 - 0.0007 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 KLO14011.1 - 0.0082 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KLO14011.1 - 0.011 16.1 0.5 0.045 14.1 0.5 2.2 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 KLO14011.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 KLO14011.1 - 0.083 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 KLO14011.1 - 0.15 11.6 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain adh_short PF00106.25 KLO14012.1 - 2.5e-30 105.4 0.1 1.2e-22 80.3 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KLO14012.1 - 2.6e-23 82.8 0.0 3.1e-20 72.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO14012.1 - 0.00032 20.7 0.1 0.00052 20.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Pox_Rif PF03340.13 KLO14012.1 - 0.011 14.2 0.0 0.016 13.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus rifampicin resistance protein Glyco_trans_4_2 PF13477.6 KLO14012.1 - 0.051 13.6 0.0 5.4 7.0 0.0 2.9 3 0 0 3 3 3 0 Glycosyl transferase 4-like NAD_binding_10 PF13460.6 KLO14012.1 - 0.075 12.9 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 KLO14012.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AA_kinase PF00696.28 KLO14013.1 - 5.6e-38 130.9 0.0 9.4e-37 126.9 0.0 2.2 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KLO14013.1 - 1.5e-11 43.9 0.3 2.8e-06 27.0 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KLO14013.1 - 5.4e-09 35.7 1.2 1.3e-07 31.3 0.2 2.5 2 0 0 2 2 2 1 ACT domain Ndc1_Nup PF09531.10 KLO14014.1 - 0.066 11.9 3.1 0.066 11.9 3.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aminotran_1_2 PF00155.21 KLO14014.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II SPX PF03105.19 KLO14014.1 - 1.1 9.1 8.9 1.5 8.7 8.9 1.3 1 0 0 1 1 1 0 SPX domain Methyltransf_16 PF10294.9 KLO14017.1 - 7.7e-06 25.7 0.1 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_31 PF13847.6 KLO14017.1 - 0.0066 16.2 0.0 0.45 10.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO14017.1 - 0.0073 17.0 0.1 0.81 10.5 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO14017.1 - 0.062 13.1 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Metallophos PF00149.28 KLO14018.1 - 3.8e-36 125.5 0.0 5.6e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UNC-50 PF05216.13 KLO14019.1 - 6.7e-84 280.9 17.0 7.6e-84 280.7 17.0 1.0 1 0 0 1 1 1 1 UNC-50 family MgtE PF01769.16 KLO14019.1 - 2.8 8.3 9.1 0.13 12.7 0.6 2.2 2 0 0 2 2 2 0 Divalent cation transporter zf-MYND PF01753.18 KLO14022.1 - 5.5e-10 39.2 12.9 9.9e-10 38.4 12.9 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KLO14022.1 - 1.8 9.0 8.5 3.9 7.9 8.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding adh_short PF00106.25 KLO14023.1 - 4.4e-19 68.7 0.0 4e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KLO14023.1 - 3.1e-08 33.5 0.0 5.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO14023.1 - 0.00051 20.0 0.1 0.0018 18.2 0.0 1.8 2 0 0 2 2 2 1 KR domain CNH PF00780.22 KLO14025.1 - 0.016 14.8 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 CNH domain DUF2244 PF10003.9 KLO14028.1 - 0.052 13.2 0.2 0.052 13.2 0.2 1.7 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4231 PF14015.6 KLO14028.1 - 7.1 7.2 13.0 3 8.4 1.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4231) Ion_trans_2 PF07885.16 KLO14029.1 - 2.9e-30 104.0 30.6 1.6e-17 63.2 7.5 3.3 3 0 0 3 3 3 2 Ion channel FAD_binding_4 PF01565.23 KLO14030.1 - 2.1e-21 76.1 0.5 3.9e-21 75.3 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KLO14030.1 - 8.4e-10 38.6 0.3 1.6e-09 37.7 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like Pribosyltran PF00156.27 KLO14031.1 - 2.2e-17 63.0 0.1 3.6e-17 62.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DER1 PF04511.15 KLO14032.1 - 1.9e-31 109.5 10.1 2.3e-31 109.2 10.1 1.0 1 0 0 1 1 1 1 Der1-like family CorA PF01544.18 KLO14034.1 - 3.2e-10 39.8 1.2 5e-10 39.2 1.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Fib_alpha PF08702.10 KLO14034.1 - 0.97 9.6 2.5 1.7 8.8 2.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Mg_trans_NIPA PF05653.14 KLO14036.1 - 1.3e-101 339.7 16.9 1.6e-101 339.3 16.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA FAM104 PF15434.6 KLO14036.1 - 0.077 13.6 1.7 0.13 12.9 1.7 1.3 1 0 0 1 1 1 0 Family 104 EamA PF00892.20 KLO14036.1 - 6.1 7.0 31.6 0.045 13.9 5.7 3.8 3 1 0 3 3 3 0 EamA-like transporter family AAA_12 PF13087.6 KLO14037.1 - 8e-44 149.6 0.0 1.4e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KLO14037.1 - 7e-27 94.8 0.0 3.5e-12 46.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KLO14037.1 - 1.1e-11 44.8 0.0 3.5e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO14037.1 - 1.6e-08 35.0 0.0 6e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain zf-met PF12874.7 KLO14037.1 - 1.7e-06 28.2 12.6 8.6e-05 22.8 0.3 4.1 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KLO14037.1 - 0.00019 21.6 3.8 0.00084 19.6 0.1 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding ResIII PF04851.15 KLO14037.1 - 0.0012 18.9 0.0 0.0036 17.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KLO14037.1 - 0.0095 15.5 0.0 0.088 12.3 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KLO14037.1 - 0.013 15.8 0.0 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 KLO14037.1 - 0.015 15.7 0.3 0.015 15.7 0.3 3.4 4 0 0 4 4 2 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KLO14037.1 - 0.025 14.9 4.7 0.22 11.9 0.7 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 KLO14037.1 - 0.027 14.9 1.7 2.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D AAA_16 PF13191.6 KLO14037.1 - 0.037 14.4 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KLO14037.1 - 0.062 13.7 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KLO14037.1 - 0.11 11.7 0.0 0.31 10.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KLO14037.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KLO14037.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zf_RING PF16744.5 KLO14037.1 - 0.23 11.6 2.3 0.6 10.3 2.3 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger ChAPs PF09295.10 KLO14038.1 - 4.2e-147 490.3 0.0 3e-145 484.2 0.0 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KLO14038.1 - 0.00011 22.6 7.6 0.0022 18.5 0.1 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KLO14038.1 - 0.012 15.8 2.8 0.29 11.5 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 KLO14038.1 - 0.021 14.0 5.0 1.3 8.2 0.9 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KLO14038.1 - 0.034 14.0 0.4 14 5.7 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KLO14038.1 - 0.054 14.3 6.0 26 6.0 0.0 6.4 4 2 4 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 KLO14038.1 - 0.12 13.1 7.3 3.3 8.6 0.0 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KLO14038.1 - 0.14 12.4 15.4 1.8 8.9 0.2 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat DUF2046 PF09755.9 KLO14039.1 - 3.6e-09 36.3 9.3 1.2e-08 34.6 6.5 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Cnn_1N PF07989.11 KLO14039.1 - 0.015 15.5 0.3 6.5 7.0 0.0 2.5 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 ATG16 PF08614.11 KLO14039.1 - 4.9 7.3 11.3 2.8 8.1 0.8 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) HSP20 PF00011.21 KLO14040.1 - 7.3e-12 45.3 0.7 2.6e-11 43.5 0.0 2.2 3 0 0 3 3 3 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KLO14040.1 - 0.065 12.8 0.0 0.37 10.4 0.0 2.0 1 1 0 1 1 1 0 HSP20-like domain found in ArsA SOG2 PF10428.9 KLO14040.1 - 1.2 8.3 23.0 1.5 7.9 23.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAT1 PF09770.9 KLO14040.1 - 8.3 4.5 20.7 11 4.2 20.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LtrA PF06772.11 KLO14041.1 - 0.028 13.6 0.7 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) RhoGEF PF00621.20 KLO14042.1 - 1.3e-06 28.8 0.1 2.8e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 KLO14043.1 - 1.9e-13 50.7 0.0 2.2e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 CNH domain Phage_attach PF05354.11 KLO14043.1 - 0.12 12.3 0.1 1.3 8.9 0.3 2.1 1 1 1 2 2 2 0 Phage Head-Tail Attachment TPR_12 PF13424.6 KLO14044.1 - 1.6e-15 57.1 8.7 4.3e-06 26.9 0.0 4.3 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO14044.1 - 8.2e-13 48.4 0.7 6.2e-07 29.1 0.5 3.1 2 1 0 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KLO14044.1 - 9e-11 41.0 12.8 0.0043 17.1 0.1 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat NACHT PF05729.12 KLO14044.1 - 1.4e-06 28.4 0.0 2.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KLO14044.1 - 6.3e-06 26.5 0.0 2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_7 PF13176.6 KLO14044.1 - 1.3e-05 24.9 2.6 0.046 13.7 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KLO14044.1 - 2.3e-05 24.3 9.4 0.042 14.1 0.0 5.7 7 0 0 7 7 6 2 Tetratricopeptide repeat NB-ARC PF00931.22 KLO14044.1 - 3.4e-05 23.2 0.0 6.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KLO14044.1 - 5.6e-05 23.6 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_14 PF13428.6 KLO14044.1 - 8.9e-05 23.0 13.7 2.8 9.0 0.1 6.2 6 1 1 7 7 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 KLO14044.1 - 0.00014 22.2 0.0 0.001 19.5 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain TPR_1 PF00515.28 KLO14044.1 - 0.00042 20.0 10.9 0.0032 17.2 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KLO14044.1 - 0.00055 19.7 8.4 0.35 10.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KLO14044.1 - 0.036 14.7 16.0 1.1 10.1 3.3 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat ComR_TPR PF18710.1 KLO14044.1 - 0.037 13.6 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 ComR tetratricopeptide RuvB_N PF05496.12 KLO14044.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KLO14044.1 - 0.06 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KLO14044.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_21 PF09976.9 KLO14044.1 - 0.11 12.2 5.1 18 5.0 2.2 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain 4HPAD_g_N PF18671.1 KLO14044.1 - 0.16 11.7 0.0 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal TPR_16 PF13432.6 KLO14044.1 - 0.52 11.0 26.5 9.8 6.9 0.0 6.2 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KLO14044.1 - 1.2 9.7 0.0 1.2 9.7 0.0 4.2 3 1 0 4 4 3 0 Tetratricopeptide repeat RNA_pol_L_2 PF13656.6 KLO14045.1 - 4.6e-27 93.6 0.0 6.2e-27 93.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KLO14045.1 - 2.5e-06 26.8 0.0 4.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DDE_1 PF03184.19 KLO14049.1 - 1.2e-17 64.1 0.0 1.6e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KLO14050.1 - 0.00016 21.7 0.1 0.00018 21.5 0.1 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Unstab_antitox PF09720.10 KLO14050.1 - 0.014 15.4 0.2 0.018 15.1 0.2 1.2 1 0 0 1 1 1 0 Putative addiction module component DarA_N PF18788.1 KLO14058.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Defence against restriction A N-terminal Cytochrom_C1 PF02167.15 KLO14058.1 - 0.17 11.5 0.2 0.51 10.0 0.1 1.7 1 1 1 2 2 2 0 Cytochrome C1 family F-box-like PF12937.7 KLO14062.1 - 5.9e-06 26.1 0.7 5.9e-06 26.1 0.7 1.9 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KLO14062.1 - 0.15 12.0 0.4 0.52 10.3 0.4 1.9 1 1 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 KLO14063.1 - 2.2e-07 30.7 0.8 1.7e-06 27.8 0.2 2.8 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KLO14063.1 - 0.0012 18.8 0.6 0.0048 16.8 0.1 2.2 2 1 0 2 2 2 1 F-box-like domain F-box PF00646.33 KLO14063.1 - 0.42 10.6 2.7 2.6 8.0 0.8 3.1 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO14064.1 - 0.0018 18.1 2.7 0.0062 16.4 2.7 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO14064.1 - 0.017 15.0 4.0 3.7 7.5 3.8 3.6 2 1 1 3 3 3 0 F-box domain BioW PF03744.13 KLO14067.1 - 0.0032 17.0 0.0 0.0041 16.7 0.0 1.1 1 0 0 1 1 1 1 6-carboxyhexanoate--CoA ligase Pinin_SDK_N PF04697.13 KLO14071.1 - 0.07 13.8 3.5 2.5 8.7 0.0 2.7 2 0 0 2 2 2 0 pinin/SDK conserved region CENP-B_dimeris PF09026.10 KLO14071.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 KLO14071.1 - 0.25 11.7 2.9 2.3 8.6 0.1 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KLO14071.1 - 0.59 9.8 2.7 0.84 9.3 0.3 2.4 2 0 0 2 2 2 0 FAM176 family Pox_Ag35 PF03286.14 KLO14071.1 - 5.4 6.7 10.1 2.9 7.6 4.9 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein F-box-like PF12937.7 KLO14074.1 - 3.7e-05 23.5 0.4 0.00014 21.7 0.4 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO14074.1 - 0.038 13.9 3.3 0.25 11.3 1.7 2.9 2 0 0 2 2 2 0 F-box domain PITH PF06201.13 KLO14074.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 PITH domain zf-U11-48K PF05253.12 KLO14074.1 - 0.15 12.0 4.9 2.2 8.3 1.0 3.2 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger F-box-like PF12937.7 KLO14076.1 - 2.7e-08 33.6 0.5 1e-07 31.7 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KLO14076.1 - 0.0036 17.2 0.2 0.016 15.2 0.0 2.1 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.33 KLO14076.1 - 2 8.4 9.6 19 5.3 0.0 4.2 2 1 1 3 3 3 0 F-box domain LRR_4 PF12799.7 KLO14076.1 - 2.2 8.8 5.7 11 6.6 1.4 3.4 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO14077.1 - 0.00027 20.7 1.0 0.0014 18.5 0.3 2.6 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KLO14077.1 - 0.021 14.8 0.0 0.066 13.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like domain LRR_4 PF12799.7 KLO14077.1 - 0.1 13.0 0.9 27 5.4 0.0 4.7 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO14078.1 - 4.1e-06 26.6 2.7 6.2e-06 26.0 0.6 2.3 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KLO14078.1 - 0.28 11.2 2.3 0.31 11.0 0.4 2.1 2 1 0 2 2 2 0 F-box-like domain F-box-like PF12937.7 KLO14081.1 - 2.7e-09 36.8 3.4 8.7e-08 31.9 0.7 2.8 2 0 0 2 2 2 2 F-box-like F-box-like PF12937.7 KLO14082.1 - 5.7e-05 22.9 0.5 0.00018 21.3 0.5 1.9 1 0 0 1 1 1 1 F-box-like Vps35 PF03635.17 KLO14082.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 F-box-like PF12937.7 KLO14083.1 - 2.3e-06 27.4 0.5 5.8e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO14084.1 - 2.3e-08 33.8 0.0 9.8e-08 31.8 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO14084.1 - 0.48 10.4 4.2 0.27 11.2 0.4 2.6 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO14085.1 - 0.044 13.7 1.0 0.1 12.5 1.0 1.7 1 1 0 1 1 1 0 F-box-like Keratin PF02422.16 KLO14085.1 - 0.12 12.1 0.1 0.17 11.6 0.1 1.3 1 1 0 1 1 1 0 Keratin F-box-like PF12937.7 KLO14086.1 - 1.7e-06 27.8 0.0 5.4e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO14087.1 - 3.8e-08 33.1 0.2 1.3e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO14087.1 - 0.086 12.7 3.8 3.3 7.7 3.5 3.2 2 1 0 2 2 2 0 F-box domain Erf4 PF10256.9 KLO14088.1 - 0.00063 19.8 0.0 0.0019 18.3 0.0 1.8 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family Erf4 PF10256.9 KLO14089.1 - 0.00037 20.6 0.0 0.00048 20.2 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family adh_short_C2 PF13561.6 KLO14091.1 - 7.7e-25 87.8 0.1 9.7e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO14091.1 - 3e-16 59.5 0.0 4.3e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO14091.1 - 2e-07 31.1 0.3 3e-07 30.5 0.3 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KLO14091.1 - 0.052 12.7 0.1 0.068 12.3 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2856 PF11043.8 KLO14091.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) zf-RVT PF13966.6 KLO14092.1 - 0.0015 19.2 0.1 0.0025 18.5 0.1 1.5 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Baculo_FP PF03258.14 KLO14092.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Baculovirus FP protein DUF4772 PF15997.5 KLO14093.1 - 0.13 12.9 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4772) F-box-like PF12937.7 KLO14096.1 - 4e-07 29.8 0.2 3.8e-06 26.7 0.0 2.7 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO14096.1 - 0.00092 19.6 1.5 0.99 9.9 0.5 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO14097.1 - 5e-08 32.7 2.1 3.4e-06 26.8 0.1 2.6 2 0 0 2 2 2 2 F-box-like F-box-like PF12937.7 KLO14098.1 - 1.7e-10 40.6 2.4 2e-09 37.2 0.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO14098.1 - 0.00026 20.8 0.1 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KLO14098.1 - 0.45 11.0 5.5 5.6 7.5 0.2 4.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) HMG_box PF00505.19 KLO14100.1 - 1.6e-14 54.0 3.6 3.3e-14 53.0 3.6 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO14100.1 - 3.3e-07 30.8 0.2 4.7e-07 30.3 0.2 1.3 1 0 0 1 1 1 1 HMG-box domain STE3 PF02076.15 KLO14101.1 - 5.2e-71 239.2 15.9 6.1e-71 239.0 15.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor 7tm_3 PF00003.22 KLO14101.1 - 4e-05 23.4 8.1 4.3e-05 23.4 5.9 2.0 1 1 1 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Ninjurin PF04923.12 KLO14101.1 - 0.022 14.7 2.2 0.076 13.0 2.0 2.0 1 1 0 1 1 1 0 Ninjurin F-box-like PF12937.7 KLO14102.1 - 0.00019 21.3 0.1 0.00055 19.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO14102.1 - 0.017 15.0 4.2 0.19 11.6 4.2 2.4 1 1 0 1 1 1 0 F-box domain DUF4325 PF14213.6 KLO14102.1 - 0.13 12.0 0.0 12 5.7 0.0 2.2 2 0 0 2 2 2 0 STAS-like domain of unknown function (DUF4325) F-box-like PF12937.7 KLO14103.1 - 0.00011 22.0 0.3 0.00029 20.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO14103.1 - 0.0011 18.7 0.8 0.0037 17.1 0.8 2.0 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KLO14103.1 - 1.2 9.6 4.5 19 5.9 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) NAC PF01849.18 KLO14104.1 - 1.7e-22 79.1 0.1 3.3e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 NAC domain Cofilin_ADF PF00241.20 KLO14105.1 - 2.6e-25 88.6 0.1 3e-25 88.4 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein F-box-like PF12937.7 KLO14106.1 - 6.4e-05 22.8 1.4 0.00013 21.8 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO14106.1 - 0.001 18.9 1.3 0.0049 16.7 1.3 2.1 1 1 0 1 1 1 1 F-box domain Neugrin PF06413.11 KLO14107.1 - 3.6e-14 53.3 1.0 5e-14 52.9 0.6 1.3 1 1 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 KLO14107.1 - 1.1e-07 32.2 2.1 1.2e-07 32.1 1.4 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 MarR_2 PF12802.7 KLO14107.1 - 0.015 15.2 0.1 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 MarR family Put_DNA-bind_N PF06971.13 KLO14107.1 - 0.083 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus FeoC PF09012.10 KLO14107.1 - 0.1 12.7 0.2 5 7.3 0.0 2.3 1 1 1 2 2 2 0 FeoC like transcriptional regulator ASL_C PF08328.11 KLO14107.1 - 0.1 12.7 0.3 0.13 12.4 0.3 1.2 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal SUKH-3 PF14433.6 KLO14107.1 - 0.13 12.8 0.0 0.16 12.5 0.0 1.4 1 1 0 1 1 1 0 SUKH-3 immunity protein F-box-like PF12937.7 KLO14108.1 - 5.9e-16 58.1 4.9 7.6e-08 32.1 0.5 2.9 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KLO14108.1 - 6e-06 26.0 14.3 0.0058 16.5 0.4 4.0 3 1 0 3 3 3 2 F-box domain Acetyltransf_1 PF00583.25 KLO14109.1 - 4.3e-15 56.0 0.0 5.3e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KLO14109.1 - 2.7e-06 27.7 0.0 3.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO14109.1 - 9.5e-06 25.6 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO14109.1 - 0.00014 21.7 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KLO14109.1 - 0.00052 20.7 0.0 0.00066 20.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KLO14109.1 - 0.0012 18.9 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 KLO14109.1 - 0.085 12.3 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase F-box-like PF12937.7 KLO14110.1 - 2.2e-06 27.5 0.3 1.1e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO14110.1 - 1.3 9.0 5.6 1.2 9.1 1.7 2.9 2 1 0 2 2 2 0 F-box domain XPG_I PF00867.18 KLO14111.1 - 1.4e-14 54.2 0.0 2.8e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KLO14111.1 - 1.6e-07 31.7 0.0 3.5e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain MIOX PF05153.15 KLO14112.1 - 3.5e-129 429.7 2.1 4.2e-129 429.4 2.1 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KLO14112.1 - 0.0007 19.8 0.3 0.13 12.5 0.0 2.9 2 1 1 3 3 3 1 HD domain DUF1796 PF08795.10 KLO14112.1 - 0.054 13.4 0.4 0.089 12.7 0.4 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Transket_pyr PF02779.24 KLO14113.1 - 9.9e-61 204.5 0.0 1.5e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KLO14113.1 - 1.5e-44 151.4 0.0 2.4e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KLO14113.1 - 3e-40 138.0 0.0 5.6e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Pkinase_Tyr PF07714.17 KLO14114.1 - 3.2e-37 128.2 0.0 5.3e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO14114.1 - 3.9e-33 114.9 0.0 7e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO14114.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF2019 PF09450.10 KLO14114.1 - 0.16 11.9 1.4 0.26 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) Yop-YscD_ppl PF16693.5 KLO14114.1 - 6.5 6.1 6.8 2.4 7.6 1.4 2.4 1 1 2 3 3 3 0 Inner membrane component of T3SS, periplasmic domain DEAD PF00270.29 KLO14115.1 - 2.7e-15 56.6 0.0 5.3e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO14115.1 - 2.3e-10 40.7 0.0 7.4e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KLO14115.1 - 1.1e-05 25.7 0.0 3.3e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERG2_Sigma1R PF04622.12 KLO14116.1 - 1.7e-92 308.5 0.1 2e-92 308.3 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein F-box-like PF12937.7 KLO14118.1 - 0.00011 22.0 3.0 0.00014 21.7 0.4 2.6 2 0 0 2 2 2 1 F-box-like Cys_rich_VLP PF14194.6 KLO14118.1 - 0.21 11.7 0.2 0.53 10.5 0.2 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP Pkinase PF00069.25 KLO14121.1 - 2.6e-42 145.0 0.0 3.2e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO14121.1 - 1.2e-38 132.9 0.0 1.5e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO14121.1 - 0.0004 19.3 0.0 0.00052 18.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KLO14121.1 - 0.00065 19.3 0.5 0.0086 15.7 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.6 KLO14121.1 - 0.0018 17.6 0.1 0.0047 16.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KLO14121.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO14121.1 - 0.038 13.9 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family STE3 PF02076.15 KLO14122.1 - 2.6e-70 236.9 21.5 3e-70 236.7 21.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor F-box-like PF12937.7 KLO14123.1 - 5.2e-07 29.5 0.9 1.4e-06 28.1 0.9 1.8 1 0 0 1 1 1 1 F-box-like DUF2235 PF09994.9 KLO14124.1 - 5.3e-79 265.6 2.4 1.6e-78 264.0 2.4 1.7 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) RNA_pol_I_TF PF04090.12 KLO14124.1 - 0.041 13.4 0.0 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase I specific initiation factor Secretin_N_2 PF07655.13 KLO14124.1 - 0.45 11.1 5.2 0.87 10.2 0.1 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain F-box-like PF12937.7 KLO14125.1 - 8.2e-05 22.4 2.1 0.00024 20.9 0.8 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO14126.1 - 3.3e-06 26.9 0.4 9.9e-06 25.4 0.4 1.8 1 0 0 1 1 1 1 F-box-like STE3 PF02076.15 KLO14127.1 - 4.8e-64 216.3 17.9 5.7e-64 216.1 17.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 KLO14128.1 - 5.9e-72 242.3 20.9 6.7e-72 242.1 20.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor SPC25 PF06703.11 KLO14129.1 - 1.7e-54 184.0 0.1 1.9e-54 183.8 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MASE3 PF17159.4 KLO14129.1 - 0.036 13.7 0.2 0.048 13.3 0.2 1.1 1 0 0 1 1 1 0 Membrane-associated sensor domain TRAP-gamma PF07074.12 KLO14129.1 - 0.057 13.0 0.1 0.078 12.5 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Phytoreo_Pns PF05451.11 KLO14129.1 - 0.1 11.7 0.1 0.27 10.3 0.0 1.6 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns10/11 ERG2_Sigma1R PF04622.12 KLO14130.1 - 1.4e-98 328.4 0.1 1.6e-98 328.2 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein F-box-like PF12937.7 KLO14132.1 - 3.1e-08 33.4 0.2 4.4e-07 29.7 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO14132.1 - 0.91 9.5 6.7 6.8 6.7 0.2 3.6 4 0 0 4 4 4 0 F-box domain STE3 PF02076.15 KLO14134.1 - 7e-56 189.6 29.2 2.5e-55 187.7 29.2 1.7 1 1 0 1 1 1 1 Pheromone A receptor HPS3_Mid PF14762.6 KLO14134.1 - 0.06 12.1 1.7 0.085 11.6 1.7 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region STE3 PF02076.15 KLO14136.1 - 4.1e-63 213.3 11.9 4.7e-63 213.1 11.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor SOG2 PF10428.9 KLO14137.1 - 2.7 7.1 13.4 3.6 6.7 13.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 KLO14137.1 - 2.8 6.4 6.0 3.6 6.0 6.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF4611 PF15387.6 KLO14138.1 - 2.3 8.5 5.2 3.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pkinase_Tyr PF07714.17 KLO14139.1 - 5.9e-45 153.6 0.0 8.5e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO14139.1 - 1.4e-43 149.2 0.0 1.8e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO14139.1 - 0.00023 20.6 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO14139.1 - 0.024 13.4 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KLO14139.1 - 0.16 10.9 0.0 12 4.7 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain DUF4611 PF15387.6 KLO14140.1 - 0.2 11.9 2.1 9.6 6.5 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pkinase_Tyr PF07714.17 KLO14143.1 - 1.6e-40 139.0 0.0 2.3e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO14143.1 - 2.7e-36 125.3 0.0 4.4e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KLO14143.1 - 0.00019 20.4 0.1 0.00025 19.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO14143.1 - 0.002 18.1 0.1 0.002 18.1 0.1 1.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO14143.1 - 0.0036 16.7 0.0 0.025 13.9 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Apc15p PF05841.11 KLO14144.1 - 0.011 16.6 0.0 0.035 14.9 0.0 1.8 1 0 0 1 1 1 0 Apc15p protein GATA PF00320.27 KLO14145.1 - 1.3e-15 56.7 5.1 2e-15 56.1 5.1 1.3 1 0 0 1 1 1 1 GATA zinc finger DUF3039 PF11238.8 KLO14145.1 - 0.19 11.5 0.7 8.1 6.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3039) TF_Zn_Ribbon PF08271.12 KLO14145.1 - 0.23 11.0 1.9 0.38 10.3 1.9 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding HycH PF07450.11 KLO14146.1 - 0.059 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Zn_clus PF00172.18 KLO14147.1 - 7.7e-06 25.9 3.6 1.1e-05 25.5 3.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KLO14148.1 - 5.6e-17 62.0 0.1 1.7e-09 37.4 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KLO14148.1 - 0.00067 19.8 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO14148.1 - 0.0078 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KLO14148.1 - 0.017 14.3 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KLO14148.1 - 0.066 12.8 0.1 0.15 11.6 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.16 KLO14148.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zf-MYND PF01753.18 KLO14149.1 - 3.2e-09 36.7 12.1 7.1e-09 35.6 12.1 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO14150.1 - 5.9e-09 35.9 11.5 1.3e-08 34.8 11.5 1.6 1 0 0 1 1 1 1 MYND finger Pkinase_Tyr PF07714.17 KLO14151.1 - 8e-39 133.5 0.0 9.1e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO14151.1 - 1.2e-37 129.7 0.0 1.6e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO14151.1 - 9.3e-06 25.1 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO14151.1 - 2.1e-05 23.5 0.1 2.7e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO14151.1 - 0.046 13.1 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2733 PF10813.8 KLO14151.1 - 0.085 12.6 0.6 0.46 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) YrbL-PhoP_reg PF10707.9 KLO14151.1 - 0.19 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Transferase PF02458.15 KLO14152.1 - 5.6e-31 107.7 0.0 1.2e-30 106.6 0.0 1.4 1 1 0 1 1 1 1 Transferase family Hydrolase_4 PF12146.8 KLO14153.1 - 1.2e-54 185.1 0.0 1.4e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KLO14153.1 - 4.6e-11 42.9 0.0 7e-09 35.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO14153.1 - 5.1e-10 40.3 0.0 6.2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KLO14153.1 - 5.7e-07 29.2 0.0 0.00075 19.0 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 KLO14153.1 - 0.0029 16.3 0.0 0.84 8.2 0.0 2.8 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KLO14153.1 - 0.0035 17.2 0.3 1.9 8.2 0.0 2.7 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.20 KLO14153.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KLO14153.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 KLO14153.1 - 0.021 14.4 0.0 4.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Macro PF01661.21 KLO14154.1 - 2.6e-42 143.6 0.2 3.9e-42 143.0 0.2 1.3 1 0 0 1 1 1 1 Macro domain Glyco_hydro_127 PF07944.12 KLO14155.1 - 1.6e-122 409.7 0.0 1.8e-122 409.5 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_47 PF01532.20 KLO14156.1 - 2.3e-129 432.3 0.0 2.6e-129 432.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 KLO14156.1 - 0.0073 15.9 0.4 0.31 10.5 0.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Pkinase_Tyr PF07714.17 KLO14157.1 - 4.6e-41 140.8 0.0 6.4e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO14157.1 - 9.4e-36 123.5 0.0 1.4e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KLO14157.1 - 0.0024 16.7 0.0 0.0045 15.8 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KLO14157.1 - 0.036 13.4 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF1896 PF08989.10 KLO14159.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) Methyltransf_25 PF13649.6 KLO14160.1 - 0.019 15.7 0.0 0.045 14.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MULE PF10551.9 KLO14160.1 - 0.17 12.3 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 MULE transposase domain EF-hand_1 PF00036.32 KLO14161.1 - 2.9e-22 76.5 1.4 2.7e-05 23.4 0.1 5.0 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KLO14161.1 - 2.3e-21 73.9 0.9 2.9e-05 23.6 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KLO14161.1 - 1.5e-19 70.2 0.0 3.7e-09 36.9 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KLO14161.1 - 1.2e-16 59.4 1.9 0.00052 19.4 0.0 4.5 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KLO14161.1 - 2.5e-14 52.8 4.1 2.3e-08 33.8 0.1 4.2 3 2 1 4 4 4 4 EF-hand domain pair GUN4 PF05419.12 KLO14161.1 - 0.028 14.5 0.0 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 GUN4-like EF-hand_4 PF12763.7 KLO14161.1 - 0.13 12.2 2.2 0.15 12.0 0.3 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand AMP-binding PF00501.28 KLO14162.1 - 2.1e-91 306.6 0.0 2.8e-91 306.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KLO14162.1 - 0.001 20.0 0.2 0.0084 17.1 0.2 2.2 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KLO14164.1 - 4.2e-29 101.6 28.3 6.7e-29 100.9 28.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M24 PF00557.24 KLO14165.1 - 1.3e-40 139.4 0.0 2e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KLO14165.1 - 2e-05 25.3 0.0 4.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain IATP PF04568.12 KLO14166.1 - 0.041 14.3 4.1 0.043 14.2 3.6 1.3 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Cellulase PF00150.18 KLO14167.1 - 6.4e-10 38.9 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4064 PF13273.6 KLO14167.1 - 0.0025 18.1 0.2 0.0059 16.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) CBFD_NFYB_HMF PF00808.23 KLO14169.1 - 3e-06 27.4 0.0 4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAGA-Tad1 PF12767.7 KLO14169.1 - 0.14 11.9 0.1 0.3 10.8 0.0 1.5 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Histone PF00125.24 KLO14169.1 - 0.18 12.2 0.1 0.28 11.5 0.1 1.5 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Cellulase PF00150.18 KLO14171.1 - 9.9e-11 41.6 0.0 9.9e-11 41.6 0.0 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF5326 PF17260.2 KLO14171.1 - 0.082 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5326) YqfD PF06898.11 KLO14171.1 - 0.19 10.5 0.5 2.5 6.9 0.6 2.0 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD Pectate_lyase_3 PF12708.7 KLO14172.1 - 3.1e-88 295.2 19.8 1.4e-74 250.5 4.3 3.6 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KLO14172.1 - 1.4e-09 37.5 2.4 0.00062 19.4 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DUF945 PF06097.11 KLO14172.1 - 0.015 14.4 0.0 0.039 13.1 0.0 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Acetyltransf_13 PF13880.6 KLO14173.1 - 3.8e-18 65.2 0.0 6.4e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KLO14173.1 - 4.7e-08 32.7 0.2 8.5e-08 31.9 0.2 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 KLO14173.1 - 8.6e-06 26.1 0.0 3.1e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO14173.1 - 1.4e-05 25.3 0.0 3.1e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KLO14173.1 - 0.00055 19.9 0.0 0.0014 18.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain BPL_LplA_LipB PF03099.19 KLO14174.1 - 0.086 12.8 0.0 1.1 9.2 0.0 2.1 1 1 1 2 2 2 0 Biotin/lipoate A/B protein ligase family E7 PF00527.18 KLO14174.1 - 0.18 12.1 1.3 1 9.6 0.1 2.3 1 1 1 2 2 2 0 E7 protein, Early protein Scramblase PF03803.15 KLO14175.1 - 4.1e-44 150.5 0.0 6e-43 146.7 0.0 1.9 1 1 0 1 1 1 1 Scramblase GTP_EFTU PF00009.27 KLO14176.1 - 5.4e-35 120.7 0.2 2.3e-34 118.7 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KLO14176.1 - 8e-28 96.6 1.0 1.8e-27 95.5 1.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KLO14176.1 - 2.1e-08 34.2 0.1 5.2e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KLO14176.1 - 0.00054 19.7 0.1 0.34 10.6 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KLO14176.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 KLO14176.1 - 0.0016 17.5 2.0 0.0037 16.3 0.5 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 KLO14176.1 - 0.0035 16.8 0.1 0.0087 15.5 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KLO14176.1 - 0.0066 16.4 0.8 1.6 8.6 0.0 2.7 1 1 1 2 2 2 2 RsgA GTPase CHORD PF04968.12 KLO14177.1 - 1.2e-46 157.2 16.7 2.9e-24 85.5 3.1 2.6 3 0 0 3 3 3 2 CHORD CS PF04969.16 KLO14177.1 - 1e-13 52.1 0.0 2.1e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 CS domain BTK PF00779.19 KLO14177.1 - 0.036 13.9 5.4 3.1 7.7 0.3 3.2 3 0 0 3 3 3 0 BTK motif Mito_carr PF00153.27 KLO14178.1 - 5.6e-09 35.8 0.3 0.0031 17.4 0.0 3.7 3 1 0 3 3 3 2 Mitochondrial carrier protein Pdase_M17_N2 PF18295.1 KLO14178.1 - 0.022 15.0 0.0 0.74 10.1 0.0 2.4 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 Tim17 PF02466.19 KLO14178.1 - 0.027 14.9 2.7 5.8 7.3 0.1 2.9 1 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family 2OG-FeII_Oxy_2 PF13532.6 KLO14179.1 - 1.6e-13 51.3 0.0 2.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 KLO14181.1 - 2.8e-41 138.7 15.4 8e-12 45.5 0.2 8.1 7 1 1 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO14181.1 - 7.4e-13 48.6 2.1 0.00086 19.6 0.0 4.6 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO14181.1 - 1.5e-06 27.5 0.8 1 8.3 0.0 4.2 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KLO14181.1 - 9.4e-06 24.5 1.7 0.56 8.8 0.0 4.0 2 2 0 4 4 4 3 Nucleoporin Nup120/160 Hira PF07569.11 KLO14181.1 - 0.0001 22.1 0.0 0.099 12.4 0.0 2.6 1 1 0 2 2 2 2 TUP1-like enhancer of split Nucleoporin_N PF08801.11 KLO14181.1 - 0.00056 18.8 1.9 0.11 11.3 0.0 4.3 2 2 3 5 5 5 1 Nup133 N terminal like DUF866 PF05907.13 KLO14181.1 - 0.002 18.0 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) PALB2_WD40 PF16756.5 KLO14181.1 - 0.0041 16.1 1.6 0.011 14.7 0.1 2.3 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain GATase_2 PF00310.21 KLO14182.1 - 2.6e-176 586.5 0.0 3.6e-176 586.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KLO14182.1 - 1.6e-156 521.1 0.1 1.6e-155 517.8 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KLO14182.1 - 5.3e-118 393.6 0.0 5.7e-117 390.1 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KLO14182.1 - 2.2e-87 291.6 5.3 3.6e-87 290.9 5.3 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KLO14182.1 - 8.4e-24 84.3 0.0 4e-23 82.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KLO14182.1 - 1.6e-20 73.0 0.0 3.4e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DAO PF01266.24 KLO14182.1 - 4.4e-09 36.4 0.1 0.0032 17.1 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO14182.1 - 4.7e-09 36.3 0.0 1.8e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KLO14182.1 - 3.1e-08 34.0 0.3 0.00026 21.5 0.1 4.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO14182.1 - 7.1e-08 32.1 0.4 0.016 14.5 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO14182.1 - 1.2e-05 24.2 1.3 2.1e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KLO14182.1 - 5.9e-05 22.5 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KLO14182.1 - 0.00017 20.8 0.0 0.0015 17.7 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KLO14182.1 - 0.0012 18.3 0.0 0.0012 18.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FMN_dh PF01070.18 KLO14182.1 - 0.0013 17.8 0.9 0.0051 15.9 1.1 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase FAD_binding_3 PF01494.19 KLO14182.1 - 0.0036 16.6 0.0 0.0077 15.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KLO14182.1 - 0.016 14.3 0.2 0.5 9.4 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KLO14182.1 - 0.035 13.4 0.0 1.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KLO14182.1 - 0.041 13.1 1.8 0.047 12.9 0.1 1.9 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 KLO14182.1 - 0.043 13.5 0.1 0.091 12.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KLO14182.1 - 0.045 13.7 0.2 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KLO14182.1 - 0.057 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KLO14182.1 - 0.058 13.8 0.9 3.3 8.2 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 KLO14182.1 - 0.07 13.3 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 KLO14182.1 - 0.077 12.6 0.1 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 KLO14182.1 - 0.1 12.6 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding GATase_6 PF13522.6 KLO14182.1 - 0.12 12.6 0.1 0.34 11.1 0.1 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain GIDA PF01134.22 KLO14182.1 - 0.27 10.2 1.2 0.86 8.6 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Inv-AAD PF18785.1 KLO14183.1 - 1.5e-22 79.8 0.0 2.2e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KLO14183.1 - 7.4e-15 54.7 0.0 1.2e-14 54.0 0.0 1.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KLO14183.1 - 8.8e-05 22.3 0.1 0.19 11.5 0.1 2.2 2 0 0 2 2 2 2 MafB19-like deaminase APOBEC_N PF08210.11 KLO14183.1 - 0.0017 18.3 0.0 0.14 12.0 0.0 2.1 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Condensation PF00668.20 KLO14184.1 - 2.2e-106 356.3 0.0 8.5e-36 123.6 0.1 4.3 4 0 0 4 4 4 4 Condensation domain AMP-binding PF00501.28 KLO14184.1 - 7.1e-82 275.2 0.0 3.3e-81 273.1 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KLO14184.1 - 5.2e-27 94.0 8.0 4.3e-11 43.0 0.3 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KLO14184.1 - 0.00026 21.9 0.0 0.0017 19.3 0.0 2.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain K_oxygenase PF13434.6 KLO14186.1 - 1.6e-91 307.0 0.0 2.2e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KLO14186.1 - 2.3e-06 27.7 0.0 0.00017 21.6 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KLO14186.1 - 0.0062 16.2 0.0 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO14186.1 - 0.12 11.5 0.0 0.58 9.3 0.0 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L24e PF01246.20 KLO14187.1 - 7e-33 112.7 6.4 7e-33 112.7 6.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 KLO14187.1 - 0.0071 16.3 3.7 0.013 15.4 3.7 1.5 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif HAGH_C PF16123.5 KLO14187.1 - 0.083 13.4 2.5 0.23 12.0 0.7 2.1 1 1 1 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus DUF2116 PF09889.9 KLO14187.1 - 0.76 9.8 3.5 0.39 10.7 0.8 1.9 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ATG_C PF09333.11 KLO14188.1 - 3.4e-32 110.7 0.4 1.3e-31 108.8 0.2 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 KLO14188.1 - 2.4e-13 50.1 0.1 8.1e-13 48.4 0.1 2.0 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.7 KLO14188.1 - 1e-11 45.0 0.0 4.4e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 KLO14188.1 - 0.0023 17.8 0.0 0.0068 16.2 0.0 1.8 1 1 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Choline_transpo PF04515.12 KLO14189.1 - 6.4e-46 157.0 10.0 6.4e-46 157.0 10.0 2.8 2 2 0 2 2 2 1 Plasma-membrane choline transporter Ribosomal_L37 PF08561.10 KLO14190.1 - 6.4e-19 68.7 7.4 7.8e-16 58.7 0.3 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 ANAPC4_WD40 PF12894.7 KLO14191.1 - 0.094 13.0 0.1 2.4 8.5 0.0 3.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nop14 PF04147.12 KLO14191.1 - 3 6.0 8.5 4.6 5.3 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family ADH_zinc_N PF00107.26 KLO14192.1 - 2.9e-25 88.7 0.3 4.5e-25 88.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO14192.1 - 3.1e-14 54.2 0.0 6.6e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO14192.1 - 1e-06 28.6 0.0 6.8e-06 25.9 0.0 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 KLO14192.1 - 6.7e-05 23.0 0.1 0.012 15.8 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Methyltransf_11 PF08241.12 KLO14192.1 - 0.044 14.4 1.0 0.29 11.8 0.3 2.6 2 1 0 2 2 2 0 Methyltransferase domain adh_short PF00106.25 KLO14192.1 - 0.072 12.5 0.4 0.11 11.9 0.4 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Rrp40_N PF18311.1 KLO14193.1 - 0.045 13.7 1.1 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 Exosome complex exonuclease Rrp40 N-terminal domain zf-C3HC4_3 PF13920.6 KLO14194.1 - 1.2e-05 25.0 8.4 1.2e-05 25.0 8.4 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_3rep PF18868.1 KLO14194.1 - 0.13 12.9 8.9 6.3 7.5 2.9 3.4 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats OrsD PF12013.8 KLO14194.1 - 0.58 10.6 8.9 3.2 8.2 0.0 3.7 3 1 1 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-RING_2 PF13639.6 KLO14194.1 - 1 9.7 23.9 0.23 11.8 9.2 3.3 3 0 0 3 3 3 0 Ring finger domain Fib_alpha PF08702.10 KLO14195.1 - 0.59 10.3 12.9 1.1 9.4 0.1 4.1 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.16 KLO14195.1 - 3.5 6.4 7.9 3.1 6.6 5.4 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein V-ATPase_G_2 PF16999.5 KLO14196.1 - 2.3 8.7 11.6 6 7.4 0.2 2.7 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit UCH PF00443.29 KLO14197.1 - 3.3e-42 144.7 0.0 5.1e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase COX4 PF02936.14 KLO14197.1 - 4.3e-39 133.7 0.1 7.3e-39 132.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV UCH_1 PF13423.6 KLO14197.1 - 1.8e-09 37.7 0.0 7.5e-06 25.8 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ATP-synt_Eps PF04627.13 KLO14198.1 - 5.1e-21 74.4 3.1 6.2e-21 74.1 3.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ras PF00071.22 KLO14199.1 - 9.9e-51 171.6 0.0 1.2e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO14199.1 - 3.5e-30 104.7 0.0 4.9e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO14199.1 - 2.8e-12 46.4 0.0 3.2e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KLO14199.1 - 3.3e-05 23.9 0.0 7.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KLO14199.1 - 4.4e-05 23.1 0.0 0.0012 18.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KLO14199.1 - 0.069 13.0 0.0 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DSPc PF00782.20 KLO14200.1 - 6.2e-29 100.5 0.0 6.9e-29 100.3 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4184 PF13803.6 KLO14200.1 - 0.0082 15.9 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4184) Y_phosphatase PF00102.27 KLO14200.1 - 0.011 15.3 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KLO14200.1 - 0.015 15.6 0.0 0.023 15.0 0.0 1.4 1 1 0 1 1 1 0 Rit1 DUSP-like domain Bac_GH3_C PF18034.1 KLO14200.1 - 0.055 13.2 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain DEAD PF00270.29 KLO14201.1 - 7.2e-44 149.6 2.7 7.2e-44 149.6 0.7 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO14201.1 - 7.8e-32 109.9 0.3 5.2e-30 104.1 0.1 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO14201.1 - 1.8e-06 28.1 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KLO14201.1 - 2.4e-06 27.9 0.3 0.00019 21.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KLO14201.1 - 0.0023 17.7 0.1 0.0039 16.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KLO14201.1 - 0.0075 16.3 0.2 0.029 14.3 0.2 2.1 1 1 0 1 1 1 1 Flavivirus DEAD domain UvrD-helicase PF00580.21 KLO14201.1 - 0.011 15.3 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KLO14201.1 - 0.02 14.7 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 Helicase CMS1 PF14617.6 KLO14201.1 - 0.088 12.1 0.1 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit zinc_ribbon_15 PF17032.5 KLO14202.1 - 3.3e-05 24.6 0.5 4.8e-05 24.0 0.5 1.3 1 0 0 1 1 1 1 zinc-ribbon family Zn_Tnp_IS1595 PF12760.7 KLO14202.1 - 0.015 15.2 4.5 0.04 13.9 3.8 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain RecR PF02132.15 KLO14202.1 - 0.24 11.0 1.0 2.5 7.7 0.1 2.1 2 0 0 2 2 2 0 RecR protein Rubredoxin PF00301.20 KLO14202.1 - 1.1 9.3 8.8 1.4 9.0 0.1 3.2 2 1 1 3 3 3 0 Rubredoxin Asp PF00026.23 KLO14203.1 - 2.8e-39 135.4 0.0 3.8e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO14203.1 - 0.0088 16.3 2.1 2.7 8.2 0.1 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal UCR_UQCRX_QCR9 PF05365.12 KLO14203.1 - 0.91 9.5 0.0 0.91 9.5 0.0 2.6 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Ras PF00071.22 KLO14204.1 - 1.8e-63 213.0 0.5 2.1e-63 212.8 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO14204.1 - 1.3e-35 122.2 0.1 2.5e-35 121.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO14204.1 - 1.9e-16 60.0 0.1 2.6e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KLO14204.1 - 3.8e-05 23.7 0.2 0.13 12.1 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KLO14204.1 - 4.8e-05 23.0 0.2 0.00014 21.5 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KLO14204.1 - 5e-05 22.8 0.1 9e-05 22.0 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KLO14204.1 - 7.3e-05 22.2 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KLO14204.1 - 0.00012 22.2 0.1 0.00051 20.1 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 KLO14204.1 - 0.0028 18.1 0.2 0.54 10.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KLO14204.1 - 0.017 15.5 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KLO14204.1 - 0.028 14.4 0.0 0.062 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KLO14204.1 - 0.032 14.0 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KLO14204.1 - 0.041 13.4 0.1 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region FeoB_N PF02421.18 KLO14204.1 - 0.047 13.2 0.0 0.27 10.8 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 KLO14204.1 - 0.063 13.6 0.0 0.2 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KLO14204.1 - 0.077 13.5 0.2 0.3 11.6 0.2 1.9 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 KLO14204.1 - 0.091 12.2 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein Septin PF00735.18 KLO14204.1 - 0.1 11.8 0.1 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 Septin Piwi PF02171.17 KLO14205.1 - 7.6e-73 245.4 0.0 1.2e-72 244.8 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 KLO14205.1 - 2.3e-13 49.6 0.0 6.6e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KLO14205.1 - 4.1e-12 46.2 0.4 2e-10 40.8 0.1 3.1 3 0 0 3 3 3 1 Argonaute linker 2 domain ArgoMid PF16487.5 KLO14205.1 - 1.2e-08 35.1 0.0 4.1e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 Mid domain of argonaute ArgoN PF16486.5 KLO14205.1 - 6.3e-07 30.1 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KLO14205.1 - 4.9e-05 23.2 0.0 9.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 PAZ domain SOR_SNZ PF01680.17 KLO14206.1 - 1.1e-110 368.3 6.5 1.5e-110 367.8 6.5 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KLO14206.1 - 1.5e-10 40.9 3.4 1e-07 31.6 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KLO14206.1 - 6.6e-06 25.4 2.2 0.015 14.4 0.0 2.4 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) IGPS PF00218.21 KLO14206.1 - 0.00032 19.9 0.0 0.0045 16.2 0.0 2.2 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase TetR_C_27 PF17935.1 KLO14206.1 - 0.00047 20.2 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 KLO14206.1 - 0.00073 19.0 5.5 0.015 14.7 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase NanE PF04131.14 KLO14206.1 - 0.0016 17.7 0.2 0.098 11.8 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KLO14206.1 - 0.0037 16.7 0.4 0.28 10.6 0.0 3.0 2 1 1 3 3 3 2 Histidine biosynthesis protein FMN_dh PF01070.18 KLO14206.1 - 0.01 14.9 0.0 0.024 13.7 0.0 1.6 1 0 0 1 1 1 0 FMN-dependent dehydrogenase TMP-TENI PF02581.17 KLO14206.1 - 0.042 13.2 0.4 1.7 7.9 0.0 2.6 2 0 0 2 2 2 0 Thiamine monophosphate synthase Peptidase_S66C PF17676.1 KLO14206.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain Img2 PF05046.14 KLO14208.1 - 4.7e-18 65.3 0.0 6.1e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Bot1p PF12298.8 KLO14211.1 - 1.9e-28 99.8 1.0 2.3e-28 99.5 0.2 1.5 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 KLO14211.1 - 0.0044 17.2 1.5 0.0071 16.5 0.0 2.0 3 0 0 3 3 3 1 Mitochondrial ribosomal protein subunit L20 FAM176 PF14851.6 KLO14211.1 - 4.7 6.9 5.7 33 4.1 0.1 2.2 2 0 0 2 2 2 0 FAM176 family Cyclin_N PF00134.23 KLO14212.1 - 3.8e-10 39.6 0.0 8.6e-09 35.2 0.0 2.6 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KLO14212.1 - 0.0099 16.2 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin C-terminal domain SRP-alpha_N PF04086.13 KLO14213.1 - 7.5e-51 173.8 13.1 3.3e-49 168.4 13.1 2.2 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KLO14213.1 - 1.9e-47 161.4 0.1 6.4e-47 159.7 0.1 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KLO14213.1 - 3.4e-09 36.8 0.0 1e-08 35.3 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KLO14213.1 - 7.1e-05 21.9 0.0 0.00017 20.6 0.0 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KLO14213.1 - 0.00083 19.1 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KLO14213.1 - 0.0012 18.7 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KLO14213.1 - 0.0062 16.5 0.0 0.018 14.9 0.0 1.8 1 1 0 1 1 1 1 NTPase CbiA PF01656.23 KLO14213.1 - 0.018 15.1 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KLO14213.1 - 0.022 14.0 0.2 1.5 7.9 0.1 2.3 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_31 PF13614.6 KLO14213.1 - 0.024 14.6 0.2 0.66 9.9 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KLO14213.1 - 0.035 14.3 0.0 3.2 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KLO14213.1 - 0.038 13.4 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 KLO14213.1 - 0.056 13.8 0.0 0.37 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KLO14213.1 - 0.063 13.5 0.0 1.6 9.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KLO14213.1 - 0.12 12.5 0.5 0.7 10.0 0.5 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Copine PF07002.16 KLO14213.1 - 0.19 11.1 0.1 0.86 9.0 0.0 2.0 2 0 0 2 2 2 0 Copine ADH_zinc_N PF00107.26 KLO14214.1 - 1.6e-17 63.7 0.1 8.3e-17 61.4 0.1 1.9 1 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO14214.1 - 8.5e-09 35.3 0.0 2e-08 34.0 0.0 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KLO14214.1 - 5.9e-08 33.8 0.0 1.3e-07 32.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KLO14214.1 - 0.00045 19.8 0.2 0.00072 19.1 0.2 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_2 PF16884.5 KLO14214.1 - 0.0081 16.1 0.0 0.039 13.8 0.0 2.1 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase Got1 PF04178.12 KLO14215.1 - 2.4e-20 73.0 19.9 3.5e-20 72.5 19.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4579 PF15158.6 KLO14215.1 - 3.9 7.2 6.0 0.49 10.1 1.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4579) HAGH_C PF16123.5 KLO14216.1 - 1.9e-17 63.6 0.5 3.9e-17 62.5 0.3 1.7 2 0 0 2 2 2 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KLO14216.1 - 2.7e-14 53.6 2.7 4e-13 49.8 2.7 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BcrAD_BadFG PF01869.20 KLO14216.1 - 0.0013 18.3 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Lactamase_B_2 PF12706.7 KLO14216.1 - 0.042 13.4 0.2 0.11 11.9 0.2 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF1344 PF07076.11 KLO14216.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) DUF695 PF05117.12 KLO14216.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF695) EphA2_TM PF14575.6 KLO14217.1 - 0.057 14.3 0.0 0.11 13.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain BatA PF07584.11 KLO14217.1 - 0.091 13.1 0.8 0.16 12.4 0.2 1.7 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Stevor PF17410.2 KLO14217.1 - 0.12 11.9 1.7 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Med13_C PF06333.12 KLO14217.1 - 0.13 11.5 10.4 0.18 11.0 10.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Syndecan PF01034.20 KLO14217.1 - 0.15 12.0 0.3 0.32 11.0 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain Dicty_REP PF05086.12 KLO14217.1 - 4.6 5.1 4.7 5.6 4.8 4.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Phage_Coat_B PF05356.11 KLO14217.1 - 7.6 6.5 7.3 1.2 9.1 2.8 1.9 2 0 0 2 2 2 0 Phage Coat protein B Ge1_WD40 PF16529.5 KLO14218.1 - 0.17 10.8 0.0 0.4 9.6 0.0 1.5 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF445 PF04286.12 KLO14218.1 - 0.18 11.5 9.5 0.32 10.8 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Paramyxo_ncap PF00973.19 KLO14219.1 - 0.14 11.0 0.0 0.16 10.9 0.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PPTA PF01239.22 KLO14220.1 - 2.5e-47 157.3 18.7 8.6e-11 41.2 3.0 5.8 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat MetW PF07021.12 KLO14220.1 - 0.024 14.2 0.0 0.92 9.1 0.0 2.4 2 1 0 2 2 2 0 Methionine biosynthesis protein MetW Nre_C PF04895.12 KLO14220.1 - 0.14 12.1 0.7 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 Archaeal Nre, C-terminal DUF3950 PF13132.6 KLO14220.1 - 2.5 7.9 4.6 18 5.2 1.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3950) TPR_14 PF13428.6 KLO14221.1 - 7.3e-10 38.8 15.3 0.27 12.2 0.5 11.6 10 2 3 13 13 13 1 Tetratricopeptide repeat TPR_15 PF13429.6 KLO14221.1 - 3.4e-05 23.2 1.2 0.04 13.1 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KLO14221.1 - 0.0001 21.6 7.4 0.091 11.9 0.5 5.7 2 2 3 5 5 5 1 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 KLO14221.1 - 0.00011 22.2 12.1 1.2 9.1 0.3 5.8 6 1 0 6 6 6 3 Mad3/BUB1 homology region 1 Suf PF05843.14 KLO14221.1 - 0.00024 21.2 12.4 0.035 14.1 4.9 4.7 3 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KLO14221.1 - 0.00027 21.4 3.5 0.14 12.7 0.1 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KLO14221.1 - 0.0011 19.3 5.9 2.1 8.7 0.0 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO14221.1 - 0.0012 18.8 16.0 0.28 11.4 0.0 8.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 KLO14221.1 - 0.0014 18.7 9.8 9.8 6.7 0.1 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 KLO14221.1 - 0.2 12.1 5.7 91 3.8 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KLO14221.1 - 0.22 11.7 2.9 2.4 8.4 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat NRN1 PF15056.6 KLO14222.1 - 0.0083 16.2 0.1 0.55 10.4 0.0 2.5 1 1 1 2 2 2 1 Neuritin protein family Syntaxin-6_N PF09177.11 KLO14222.1 - 0.033 14.8 0.5 0.67 10.6 0.5 2.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 KLO14222.1 - 0.04 14.3 0.2 0.093 13.1 0.2 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 KLO14222.1 - 0.078 12.9 1.3 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 Prefoldin subunit Prefoldin PF02996.17 KLO14222.1 - 0.081 12.8 0.2 0.48 10.4 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit WD40 PF00400.32 KLO14223.1 - 1.6e-16 60.3 14.0 6.9e-08 33.0 0.5 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KLO14223.1 - 0.085 11.6 0.1 1.7 7.3 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KLO14223.1 - 0.086 13.2 0.1 5.3 7.4 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain NMO PF03060.15 KLO14224.1 - 1.7e-51 175.6 0.6 2.4e-51 175.1 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KLO14224.1 - 3.8e-08 32.7 0.3 9.6e-08 31.4 0.3 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KLO14224.1 - 0.0051 15.9 0.9 0.0084 15.2 0.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyto_heme_lyase PF01265.17 KLO14226.1 - 5.9e-47 160.7 7.5 1.8e-45 155.8 7.5 2.2 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Brix PF04427.18 KLO14227.1 - 9.6e-43 146.5 0.0 1.4e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain PPL5 PF18168.1 KLO14227.1 - 0.02 14.2 3.4 0.04 13.2 3.4 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Paf1 PF03985.13 KLO14227.1 - 0.048 12.7 17.0 0.089 11.8 17.0 1.4 1 0 0 1 1 1 0 Paf1 DUF5308 PF17233.2 KLO14227.1 - 0.27 11.4 3.4 0.97 9.6 3.4 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5308) TFIIA PF03153.13 KLO14227.1 - 0.76 9.7 20.4 1.1 9.2 20.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop25 PF09805.9 KLO14227.1 - 3.7 8.0 25.6 8.7 6.8 25.6 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) TMEM214 PF10151.9 KLO14227.1 - 4.2 5.7 8.5 6 5.2 8.5 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Gpi1 PF05024.15 KLO14228.1 - 1.8e-55 188.0 13.7 4.5e-55 186.6 13.7 1.7 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) LRR_4 PF12799.7 KLO14231.1 - 0.072 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO14232.1 - 8.6e-07 28.8 0.1 1.3e-05 25.0 0.0 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO14232.1 - 0.0058 16.5 0.1 0.15 12.0 0.0 3.1 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 KLO14232.1 - 0.99 9.9 4.7 21 5.7 0.1 5.0 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO14233.1 - 7.3e-05 22.6 2.3 0.00015 21.6 0.2 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO14233.1 - 0.00044 20.1 0.0 0.0025 17.6 0.0 2.3 2 0 0 2 2 2 1 F-box domain Methyltransf_25 PF13649.6 KLO14234.1 - 1.7e-13 51.1 0.0 3.7e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO14234.1 - 1e-12 48.1 0.0 1.5e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KLO14234.1 - 5e-11 42.5 0.0 7.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KLO14234.1 - 3.3e-10 40.5 0.0 6.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO14234.1 - 2.6e-08 33.9 0.0 1.6e-07 31.3 0.0 1.9 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KLO14234.1 - 7.8e-07 28.3 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 KLO14234.1 - 2.1e-06 27.3 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KLO14234.1 - 2.2e-06 27.3 0.1 3.5e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KLO14234.1 - 4.5e-06 27.3 0.0 9.7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KLO14234.1 - 2.5e-05 24.1 0.1 6.7e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KLO14234.1 - 0.00046 19.6 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KLO14234.1 - 0.00073 19.5 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KLO14234.1 - 0.00083 18.8 0.1 0.0022 17.4 0.1 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KLO14234.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KLO14234.1 - 0.0015 18.3 0.1 0.0024 17.6 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 KLO14234.1 - 0.0016 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cons_hypoth95 PF03602.15 KLO14234.1 - 0.0063 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_24 PF13578.6 KLO14234.1 - 0.023 15.7 0.0 0.045 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2385 PF09539.10 KLO14235.1 - 0.11 13.1 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) F-box-like PF12937.7 KLO14236.1 - 4.7e-07 29.6 0.2 1.4e-06 28.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO14236.1 - 8.8e-07 28.7 0.0 3.2e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KLO14236.1 - 0.0056 17.1 19.7 0.83 10.2 0.4 6.2 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.33 KLO14237.1 - 2.5e-07 30.4 0.2 1.1e-06 28.3 0.2 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO14237.1 - 2.6e-06 27.2 1.7 2.6e-06 27.2 1.7 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO14237.1 - 0.0039 17.6 3.9 6.6 7.3 0.0 5.1 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KLO14237.1 - 0.0067 16.2 0.1 2.1 8.2 0.0 3.2 2 0 0 2 2 2 2 Leucine rich repeat Aldo_ket_red PF00248.21 KLO14238.1 - 4.7e-27 94.9 0.0 9.8e-25 87.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Pterin_4a PF01329.19 KLO14239.1 - 1.2e-12 47.8 0.0 1.7e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase MDD_C PF18376.1 KLO14240.1 - 7.1e-74 247.6 0.0 8.7e-74 247.3 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KLO14240.1 - 1.7e-07 31.3 3.8 4.1e-07 30.1 3.8 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Tox-REase-3 PF15647.6 KLO14240.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 Exo_endo_phos PF03372.23 KLO14242.1 - 1.6e-20 73.7 0.0 3.1e-20 72.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KLO14242.1 - 7.6e-10 38.9 11.6 6.8e-06 26.3 1.2 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KLO14242.1 - 1.9e-09 37.1 11.1 8.6e-07 28.6 1.8 2.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KLO14242.1 - 0.036 14.6 9.3 12 6.9 0.2 4.7 3 1 0 3 3 3 0 Leucine Rich Repeat Sensor PF13796.6 KLO14243.1 - 2.9e-06 27.4 11.0 2.9e-06 27.4 11.0 2.1 2 1 0 2 2 2 1 Putative sensor DUF2207 PF09972.9 KLO14243.1 - 0.74 8.5 1.8 2.3 6.9 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Voltage_CLC PF00654.20 KLO14244.1 - 2.1e-94 316.7 19.7 1e-93 314.4 18.0 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel E1-E2_ATPase PF00122.20 KLO14244.1 - 0.54 9.8 2.4 4.9 6.6 0.0 2.8 3 0 0 3 3 3 0 E1-E2 ATPase TAT_signal PF10518.9 KLO14244.1 - 0.79 9.7 11.3 0.72 9.8 2.6 2.9 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Zn_clus PF00172.18 KLO14245.1 - 2.1e-08 34.2 14.0 4e-08 33.2 14.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MMtag PF10159.9 KLO14246.1 - 1.4e-30 105.4 2.9 1.4e-30 105.4 2.9 2.4 2 0 0 2 2 2 1 Multiple myeloma tumor-associated APG6_N PF17675.1 KLO14246.1 - 0.34 11.5 9.8 2.2 8.8 5.4 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region FancD2 PF14631.6 KLO14246.1 - 1.8 5.9 3.3 2.2 5.6 3.3 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease THOC2_N PF16134.5 KLO14246.1 - 2.8 6.5 8.0 3.8 6.0 8.0 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus CDC45 PF02724.14 KLO14246.1 - 6 5.0 18.0 7.1 4.8 18.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Topoisom_bac PF01131.20 KLO14247.1 - 8.1e-105 351.2 0.0 1e-104 350.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-CCHC PF00098.23 KLO14247.1 - 9.1e-23 79.3 38.7 6.9e-06 25.9 4.2 4.6 4 0 0 4 4 4 4 Zinc knuckle zf-GRF PF06839.12 KLO14247.1 - 2.9e-21 75.3 15.6 3.9e-12 46.1 4.4 2.8 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.22 KLO14247.1 - 4.3e-20 71.9 0.0 9.2e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Toprim domain zf-CCHC_3 PF13917.6 KLO14247.1 - 3e-10 39.9 19.5 0.029 14.3 0.5 4.6 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_5 PF14787.6 KLO14247.1 - 0.065 13.0 18.3 0.25 11.1 1.0 4.5 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger DUF5401 PF17380.2 KLO14248.1 - 0.16 10.0 32.6 0.26 9.3 32.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Nsp1_C PF05064.13 KLO14248.1 - 0.38 10.6 2.1 0.68 9.8 2.1 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region PP2C PF00481.21 KLO14249.1 - 6.2e-23 81.7 0.0 1.2e-21 77.6 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KLO14249.1 - 1.7e-07 31.1 0.0 3.2e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KLO14249.1 - 0.013 15.4 0.2 0.7 9.8 0.0 2.6 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) UTP25 PF06862.12 KLO14253.1 - 2.7e-165 550.7 0.8 3.2e-165 550.5 0.8 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF4112 PF13430.6 KLO14254.1 - 6.1e-33 113.2 0.2 7.9e-33 112.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DJ-1_PfpI PF01965.24 KLO14256.1 - 2.6e-24 85.9 0.0 3.3e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Oxidored_q6 PF01058.22 KLO14256.1 - 0.0033 17.2 0.0 0.0064 16.3 0.0 1.4 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit ThiJ_like PF17124.5 KLO14256.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like TFIID_20kDa PF03847.13 KLO14257.1 - 5.7e-29 100.4 0.4 1.1e-28 99.5 0.4 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KLO14257.1 - 0.0027 17.9 0.0 0.0088 16.3 0.0 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KLO14257.1 - 0.0038 17.3 0.2 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit SPRR2 PF14820.6 KLO14257.1 - 0.013 15.6 8.4 0.029 14.5 8.4 1.6 1 0 0 1 1 1 0 Small proline-rich 2 Roughex PF06020.11 KLO14257.1 - 0.11 11.6 4.2 0.19 10.8 4.2 1.5 1 0 0 1 1 1 0 Drosophila roughex protein YtzH PF14165.6 KLO14257.1 - 0.34 11.3 7.0 1.1 9.6 4.7 2.2 2 0 0 2 2 2 0 YtzH-like protein SPX PF03105.19 KLO14257.1 - 0.57 10.0 6.3 0.86 9.5 6.3 1.2 1 0 0 1 1 1 0 SPX domain DUF3455 PF11937.8 KLO14258.1 - 4.2e-25 89.0 0.0 6.9e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Arylesterase PF01731.20 KLO14259.1 - 8.5e-07 29.1 0.0 7.3e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Arylesterase Reg_prop PF07494.11 KLO14259.1 - 0.0059 16.7 0.0 6.2 7.4 0.0 3.0 3 0 0 3 3 3 2 Two component regulator propeller MNHE PF01899.16 KLO14259.1 - 0.044 13.5 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit Hydrolase PF00702.26 KLO14260.1 - 7.8e-13 49.2 0.0 2.9e-12 47.3 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KLO14260.1 - 1.2e-11 45.1 0.0 1.8e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO14260.1 - 5.5e-10 39.2 0.0 1.9e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 HAD-hyrolase-like F-box-like PF12937.7 KLO14261.1 - 1.2e-06 28.3 0.1 4.6e-06 26.4 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO14261.1 - 0.061 13.2 0.0 0.26 11.2 0.0 2.2 1 0 0 1 1 1 0 F-box domain F-box_5 PF18511.1 KLO14261.1 - 0.2 11.2 1.4 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 F-box WLM PF08325.10 KLO14262.1 - 3.6e-52 177.2 0.0 4.7e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KLO14262.1 - 2.6e-09 36.2 12.5 4.3e-06 25.9 2.0 3.6 3 1 0 3 3 3 2 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KLO14262.1 - 0.00077 19.6 0.2 0.0013 18.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 SVIP PF15811.5 KLO14262.1 - 0.006 17.0 12.8 0.15 12.5 4.4 2.6 3 0 0 3 3 3 2 Small VCP/p97-interacting protein DZR PF12773.7 KLO14262.1 - 0.013 15.5 19.1 0.027 14.5 9.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon Stc1 PF12898.7 KLO14262.1 - 0.2 12.2 10.0 0.67 10.5 0.1 3.3 2 1 0 2 2 2 0 Stc1 domain PALP PF00291.25 KLO14263.1 - 3.4e-76 256.5 0.0 4.3e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KLO14263.1 - 1.8e-42 143.0 0.1 2.3e-25 88.2 0.1 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Motilin_assoc PF04643.12 KLO14263.1 - 0.031 14.1 0.0 1 9.3 0.0 2.4 1 1 1 2 2 2 0 Motilin/ghrelin-associated peptide HU-HIG PF18291.1 KLO14263.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif DUF4713 PF15831.5 KLO14265.1 - 0.0025 18.2 0.2 0.0036 17.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4713) Frizzled PF01534.17 KLO14265.1 - 0.011 14.8 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region DUF4395 PF14340.6 KLO14265.1 - 0.023 15.0 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) CD34_antigen PF06365.12 KLO14265.1 - 0.17 11.4 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family MgtC PF02308.16 KLO14266.1 - 0.013 15.8 0.4 0.017 15.4 0.4 1.1 1 0 0 1 1 1 0 MgtC family Cytomega_TRL10 PF06084.11 KLO14266.1 - 0.024 14.7 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein UPF0182 PF03699.13 KLO14266.1 - 0.034 12.3 1.1 0.036 12.2 1.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) FeoB_associated PF12669.7 KLO14266.1 - 1.8 9.0 5.1 1.4 9.4 0.3 2.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein TMEM192 PF14802.6 KLO14267.1 - 0.055 12.6 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 TMEM192 family Shisa PF13908.6 KLO14267.1 - 0.072 13.3 0.0 0.1 12.8 0.0 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator WBP-1 PF11669.8 KLO14267.1 - 6.1 7.5 5.5 39 4.9 4.7 2.4 1 1 0 1 1 1 0 WW domain-binding protein 1 DUF3510 PF12022.8 KLO14268.1 - 4.1e-27 95.0 0.0 1.3e-26 93.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 KLO14268.1 - 1.4e-26 93.1 0.3 1.4e-26 93.1 0.3 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DFF-C PF09033.10 KLO14268.1 - 4.8e-05 23.3 3.1 0.00018 21.5 0.6 2.9 3 0 0 3 3 3 1 DNA Fragmentation factor 45kDa, C terminal domain Vps51 PF08700.11 KLO14268.1 - 0.0015 18.6 0.7 0.045 13.8 0.2 3.5 3 1 0 3 3 3 1 Vps51/Vps67 Vps8 PF12816.7 KLO14269.1 - 2.1e-61 206.9 0.0 2.1e-61 206.9 0.0 2.8 4 0 0 4 4 4 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KLO14269.1 - 0.0031 17.4 0.1 2.4 8.0 0.0 3.0 3 0 0 3 3 3 2 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KLO14269.1 - 0.033 14.5 0.0 0.81 10.0 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KLO14269.1 - 0.054 14.0 0.9 0.31 11.6 0.1 2.7 2 0 0 2 2 2 0 PQQ-like domain RAG1_imp_bd PF12560.8 KLO14269.1 - 0.093 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 RAG1 importin binding WD40 PF00400.32 KLO14269.1 - 0.22 12.5 0.8 2.4 9.2 0.1 3.2 2 1 1 3 3 3 0 WD domain, G-beta repeat PHD PF00628.29 KLO14270.1 - 7e-12 45.1 7.4 1.2e-11 44.3 7.4 1.4 1 0 0 1 1 1 1 PHD-finger TP2 PF01254.18 KLO14270.1 - 0.0065 17.1 3.0 0.0065 17.1 3.0 5.5 5 1 1 6 6 6 1 Nuclear transition protein 2 zf-CW PF07496.15 KLO14270.1 - 0.1 12.6 0.7 0.24 11.4 0.7 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.6 KLO14270.1 - 0.2 11.3 1.8 0.33 10.6 1.8 1.4 1 0 0 1 1 1 0 PHD-finger PX PF00787.24 KLO14271.1 - 3.2e-28 98.0 0.5 2.1e-27 95.3 0.2 1.9 1 1 1 2 2 2 2 PX domain Sec34 PF04136.15 KLO14272.1 - 5.7e-50 169.1 0.3 1.3e-49 167.9 0.1 1.7 2 0 0 2 2 2 1 Sec34-like family CALCOCO1 PF07888.11 KLO14272.1 - 0.022 13.6 0.7 0.042 12.7 0.7 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Zw10 PF06248.13 KLO14272.1 - 0.026 13.1 0.2 0.047 12.3 0.2 1.4 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 AF-4 PF05110.13 KLO14274.1 - 5.9 4.9 7.2 7.3 4.5 7.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Melibiase_2 PF16499.5 KLO14275.1 - 2.9e-52 177.6 6.6 7.9e-52 176.2 6.6 1.7 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KLO14275.1 - 1e-09 38.3 0.0 2.7e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KLO14275.1 - 8.1e-08 31.6 0.0 1.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Melibiase DUF1484 PF07363.11 KLO14276.1 - 0.017 16.2 0.0 0.098 13.7 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) ApoLp-III PF07464.11 KLO14276.1 - 0.41 10.7 0.0 0.41 10.7 0.0 2.9 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 KLO14276.1 - 0.65 9.8 17.8 2.8 7.8 6.0 3.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain baeRF_family2 PF18844.1 KLO14276.1 - 1.8 8.6 7.9 0.13 12.4 0.6 2.6 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 2 Baculo_PEP_C PF04513.12 KLO14276.1 - 3 7.9 10.6 18 5.4 0.0 4.2 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 KLO14277.1 - 0.016 15.9 1.3 0.024 15.3 1.3 1.3 1 1 0 1 1 1 0 SlyX Cluap1 PF10234.9 KLO14277.1 - 0.022 14.1 2.4 0.023 14.1 2.4 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 CnrY PF17524.2 KLO14277.1 - 0.12 12.6 0.2 0.13 12.5 0.2 1.1 1 0 0 1 1 1 0 Anti-sigma factor CnrY HSP9_HSP12 PF04119.12 KLO14278.1 - 1.2e-24 86.5 3.8 1.2e-24 86.5 3.8 1.7 2 0 0 2 2 2 1 Heat shock protein 9/12 DUF3484 PF11983.8 KLO14278.1 - 0.069 14.3 0.1 7.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch LSM PF01423.22 KLO14280.1 - 3.2e-15 55.6 0.3 4.6e-15 55.1 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KLO14280.1 - 0.0031 17.6 0.0 0.0043 17.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain E3_binding PF02817.17 KLO14280.1 - 0.009 16.3 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain LSM14 PF12701.7 KLO14280.1 - 0.015 15.4 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain PAPA-1 PF04795.12 KLO14281.1 - 4.5e-22 78.7 0.9 4.5e-22 78.7 0.9 3.3 3 1 0 3 3 3 1 PAPA-1-like conserved region zf-RING_2 PF13639.6 KLO14282.1 - 3.7e-12 46.4 4.9 6e-12 45.7 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KLO14282.1 - 8.3e-08 31.8 1.9 8.3e-08 31.8 1.9 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KLO14282.1 - 5.5e-07 29.3 4.6 9.7e-07 28.5 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KLO14282.1 - 1.9e-05 24.9 5.0 5.7e-05 23.3 5.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KLO14282.1 - 4.6e-05 23.4 1.4 9e-05 22.5 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KLO14282.1 - 4.8e-05 23.2 2.3 8e-05 22.5 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KLO14282.1 - 0.00025 20.9 2.4 0.00042 20.1 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KLO14282.1 - 0.00049 19.8 2.9 0.00083 19.1 2.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KLO14282.1 - 0.0009 19.2 3.3 0.012 15.6 1.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KLO14282.1 - 0.0015 18.3 7.0 0.0089 15.9 7.4 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KLO14282.1 - 0.0036 17.1 1.7 0.006 16.4 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KLO14282.1 - 0.011 15.9 1.5 0.027 14.6 1.5 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KLO14282.1 - 0.013 15.6 2.4 0.024 14.8 2.4 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 KLO14282.1 - 0.14 12.1 4.2 1.1 9.3 1.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 KLO14282.1 - 0.19 11.4 3.4 0.2 11.3 2.2 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Aminotran_3 PF00202.21 KLO14283.1 - 1e-115 386.7 0.0 1.2e-115 386.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KLO14283.1 - 9.1e-06 25.1 0.0 0.0001 21.6 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DUF5375 PF17345.2 KLO14283.1 - 0.16 11.9 0.1 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5375) 2OG-FeII_Oxy_2 PF13532.6 KLO14284.1 - 8.5e-19 68.5 0.0 1.7e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP-synt_DE_N PF02823.16 KLO14285.1 - 6.9e-17 61.1 0.2 1.1e-16 60.5 0.2 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Abhydrolase_3 PF07859.13 KLO14286.1 - 2.9e-14 53.4 0.0 4.7e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KLO14286.1 - 7.3e-06 25.1 0.0 9.6e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KLO14286.1 - 2.9e-05 23.7 0.0 0.02 14.4 0.0 2.8 2 1 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KLO14286.1 - 0.0014 17.6 0.0 0.051 12.4 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase PF07224.11 KLO14286.1 - 0.039 13.0 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase His_Phos_1 PF00300.22 KLO14287.1 - 7.7e-09 35.5 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GCS PF03074.16 KLO14288.1 - 4.6e-175 582.3 0.0 5.7e-175 582.0 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 KLO14288.1 - 0.021 14.2 0.0 0.052 12.9 0.0 1.6 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) APG6 PF04111.12 KLO14289.1 - 8.7e-69 231.1 0.0 1.2e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KLO14289.1 - 3.9e-28 98.6 22.4 6.4e-28 97.9 22.4 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF812 PF05667.11 KLO14289.1 - 0.0089 15.0 6.1 0.012 14.6 6.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CAP59_mtransfer PF11735.8 KLO14289.1 - 0.2 11.3 1.8 0.33 10.6 1.8 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Vpu PF00558.19 KLO14289.1 - 0.28 11.0 3.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 Vpu protein FtsL PF04999.13 KLO14289.1 - 2.3 8.3 6.4 3.6 7.6 5.2 1.9 1 1 1 2 2 2 0 Cell division protein FtsL ERM PF00769.19 KLO14289.1 - 2.9 7.6 24.7 1.8 8.3 22.6 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family IMS PF00817.20 KLO14290.1 - 3.8e-44 150.3 0.0 6.9e-44 149.5 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KLO14290.1 - 7.1e-15 55.8 0.1 1.9e-14 54.4 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KLO14290.1 - 7e-06 26.1 0.0 1.6e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Zip PF02535.22 KLO14290.1 - 1.7 7.8 2.9 2.8 7.1 2.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RraA-like PF03737.15 KLO14291.1 - 1.4e-34 119.4 0.3 1.8e-34 119.1 0.3 1.1 1 0 0 1 1 1 1 Aldolase/RraA PA PF02225.22 KLO14291.1 - 0.022 14.8 0.3 0.042 13.9 0.3 1.5 1 0 0 1 1 1 0 PA domain Ubiq_cyt_C_chap PF03981.12 KLO14293.1 - 8.8e-24 84.2 0.0 1.4e-21 77.1 0.0 3.0 1 1 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Gln_deamidase_2 PF18626.1 KLO14293.1 - 0.064 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Glutaminase ERp29 PF07749.12 KLO14293.1 - 0.12 13.3 0.0 0.2 12.6 0.0 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain MS_channel PF00924.18 KLO14294.1 - 3.5e-21 75.7 0.2 3.5e-21 75.7 0.2 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 KLO14294.1 - 0.019 14.9 0.0 0.057 13.4 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain MS_channel PF00924.18 KLO14295.1 - 1.3e-23 83.6 0.9 2.8e-23 82.6 0.9 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KLO14295.1 - 5e-05 22.6 1.0 5e-05 22.6 1.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KLO14295.1 - 0.00019 21.1 0.4 0.00019 21.1 0.4 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KLO14295.1 - 0.00059 19.2 0.2 0.00059 19.2 0.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KLO14295.1 - 0.077 13.5 3.6 0.092 13.2 0.3 2.3 2 0 0 2 2 2 0 EF-hand domain pair DUF2207 PF09972.9 KLO14295.1 - 1.7 7.3 3.8 12 4.5 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) SNARE PF05739.19 KLO14297.1 - 1.2e-16 60.4 0.2 2e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KLO14297.1 - 6e-05 22.8 1.1 0.00022 20.9 1.1 2.0 1 1 0 1 1 1 1 Syntaxin PEP-utilisers_N PF05524.13 KLO14297.1 - 0.64 10.2 3.5 0.62 10.2 1.4 1.9 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Tmemb_9 PF05434.11 KLO14298.1 - 0.031 14.2 2.5 0.031 14.2 2.5 1.4 1 1 0 1 1 1 0 TMEM9 Arrestin_C PF02752.22 KLO14299.1 - 0.0015 19.0 0.0 0.002 18.6 0.0 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF2024 PF09630.10 KLO14299.1 - 0.079 12.8 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Ribosomal_S8 PF00410.19 KLO14300.1 - 4.5e-12 46.0 0.0 2.8e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 Aldose_epim PF01263.20 KLO14301.1 - 7.9e-63 212.5 0.1 8.9e-63 212.4 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase SIN1_PH PF16979.5 KLO14302.1 - 2.8e-29 101.6 0.1 3.7e-29 101.2 0.1 1.2 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Sec3-PIP2_bind PF15277.6 KLO14302.1 - 0.0053 16.9 0.0 0.0077 16.3 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH zf_C2H2_6 PF18450.1 KLO14308.1 - 0.4 10.4 3.3 9.1 6.1 0.2 2.6 2 0 0 2 2 2 0 Zinc Finger domain DUF2126 PF09899.9 KLO14315.1 - 0.091 10.8 0.1 0.12 10.4 0.1 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF4692 PF15763.5 KLO14316.1 - 0.073 13.5 2.0 0.13 12.7 2.0 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) MVL PF12151.8 KLO14317.1 - 0.027 14.3 0.0 0.086 12.7 0.0 1.8 1 0 0 1 1 1 0 Mannan-binding protein NAD_binding_11 PF14833.6 KLO14322.1 - 0.087 13.1 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF2015 PF09435.10 KLO14323.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.5 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2015) MHC_I_3 PF16497.5 KLO14326.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 MHC-I family domain BAF250_C PF12031.8 KLO14327.1 - 0.017 14.4 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa CsgA PF17334.2 KLO14327.1 - 0.039 14.7 0.0 0.078 13.7 0.0 1.5 1 0 0 1 1 1 0 Minor curli fiber component A Mu-conotoxin PF05374.12 KLO14331.1 - 0.049 13.6 4.1 0.085 12.9 4.1 1.4 1 0 0 1 1 1 0 Mu-Conotoxin Cation_efflux PF01545.21 KLO14333.1 - 1.8e-06 27.8 9.3 5.6e-06 26.2 9.3 1.6 1 1 0 1 1 1 1 Cation efflux family MFS_1 PF07690.16 KLO14334.1 - 3.9e-40 137.9 49.2 1.1e-38 133.0 48.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KLO14334.1 - 6.7 4.9 20.9 0.35 9.1 0.8 4.1 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family RicinB_lectin_2 PF14200.6 KLO14335.1 - 1.2e-09 38.8 0.8 0.00033 21.3 0.2 3.8 1 1 4 5 5 5 4 Ricin-type beta-trefoil lectin domain-like HTH_46 PF15977.5 KLO14335.1 - 0.21 11.7 0.0 0.9 9.6 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding DUF4791 PF16039.5 KLO14336.1 - 0.05 13.1 1.0 0.069 12.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4791) DUF5090 PF17009.5 KLO14336.1 - 8.7 6.3 10.9 0.11 12.4 1.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5090) ODV-E18 PF10717.9 KLO14337.1 - 0.017 15.0 0.1 0.045 13.6 0.0 1.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 AA_permease PF00324.21 KLO14340.1 - 3.2e-122 408.5 30.2 3.9e-122 408.3 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KLO14340.1 - 7.2e-35 120.6 29.6 9.3e-35 120.3 29.6 1.2 1 0 0 1 1 1 1 Amino acid permease EIID-AGA PF03613.14 KLO14342.1 - 0.042 13.0 0.5 0.096 11.9 0.5 1.5 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component YsaB PF13983.6 KLO14342.1 - 0.22 11.9 0.8 0.51 10.7 0.2 1.8 2 0 0 2 2 2 0 YsaB-like lipoprotein DUF3176 PF11374.8 KLO14345.1 - 4.8e-05 23.5 5.9 0.12 12.6 0.9 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3176) Mito_carr PF00153.27 KLO14346.1 - 1.6e-29 101.7 2.3 4.5e-16 58.6 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein NDUF_B12 PF08122.12 KLO14346.1 - 0.22 11.6 1.3 1 9.5 0.1 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Phasin PF05597.11 KLO14347.1 - 0.028 14.4 10.3 0.22 11.5 2.6 2.7 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CdiI_2 PF18593.1 KLO14347.1 - 0.037 14.7 2.8 0.074 13.7 0.7 2.2 2 0 0 2 2 2 0 CdiI immunity protein Fib_alpha PF08702.10 KLO14347.1 - 0.095 12.9 8.1 0.36 11.0 6.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CK2S PF15011.6 KLO14347.1 - 0.18 11.7 7.2 0.9 9.4 6.6 2.1 1 1 1 2 2 2 0 Casein Kinase 2 substrate Chal_sti_synt_N PF00195.19 KLO14347.1 - 1 8.7 4.3 1.7 8.0 3.0 1.7 1 1 1 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain DUF1664 PF07889.12 KLO14347.1 - 9 6.4 10.0 9.1 6.3 1.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AMP-binding PF00501.28 KLO14348.1 - 1.3e-30 106.3 0.0 7.4e-30 103.9 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.16 KLO14349.1 - 9.7e-41 139.8 69.0 1.5e-29 103.0 19.0 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Prosystemin PF07376.11 KLO14349.1 - 0.18 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Prosystemin DUF3176 PF11374.8 KLO14350.1 - 8.7e-06 25.9 8.7 0.024 14.8 1.5 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3176) DUF3176 PF11374.8 KLO14353.1 - 0.0013 18.9 2.4 0.0013 18.9 2.4 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3176) DUF3176 PF11374.8 KLO14354.1 - 0.0075 16.5 3.9 0.0075 16.5 3.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Phage_holin_7_1 PF16081.5 KLO14354.1 - 0.051 13.7 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF3176 PF11374.8 KLO14355.1 - 0.0056 16.9 1.4 0.0095 16.1 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Serglycin PF04360.12 KLO14356.1 - 0.045 13.7 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Serglycin DUF3176 PF11374.8 KLO14356.1 - 0.053 13.7 1.2 0.18 12.0 1.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) Metallophos PF00149.28 KLO14357.1 - 3.1e-12 47.4 3.7 6.3e-12 46.4 3.7 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KLO14357.1 - 1.3e-07 32.0 0.0 2.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KLO14357.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily ABC2_membrane PF01061.24 KLO14358.1 - 1e-76 257.0 61.5 2.4e-40 138.2 24.1 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KLO14358.1 - 1.5e-36 126.0 0.0 2.7e-17 63.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KLO14358.1 - 1.1e-30 105.4 9.6 1.3e-28 98.7 0.1 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KLO14358.1 - 3.3e-17 62.9 0.3 1e-16 61.3 0.3 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KLO14358.1 - 1.8e-06 28.0 0.1 2.7e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KLO14358.1 - 8.4e-06 26.1 0.1 0.31 11.3 0.1 3.2 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KLO14358.1 - 2.7e-05 24.6 0.1 0.009 16.4 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 KLO14358.1 - 4.2e-05 22.8 28.3 4.2e-05 22.8 28.3 3.3 2 2 0 2 2 2 1 ABC-2 family transporter protein AAA_18 PF13238.6 KLO14358.1 - 5.7e-05 23.7 0.0 0.0041 17.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KLO14358.1 - 9.2e-05 22.6 0.0 0.044 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KLO14358.1 - 0.00053 19.6 0.3 0.023 14.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KLO14358.1 - 0.0012 19.2 0.0 0.13 12.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 KLO14358.1 - 0.0029 16.9 0.0 0.43 9.8 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 KLO14358.1 - 0.0036 17.0 0.3 0.63 9.7 0.3 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KLO14358.1 - 0.0036 17.1 0.1 3.1 7.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KLO14358.1 - 0.0057 16.6 0.0 0.83 9.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 KLO14358.1 - 0.0082 16.2 0.0 0.9 9.6 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 KLO14358.1 - 0.01 15.4 0.8 0.38 10.3 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KLO14358.1 - 0.016 15.2 0.5 0.65 10.0 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SMC_N PF02463.19 KLO14358.1 - 0.019 14.4 0.0 0.3 10.5 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KLO14358.1 - 0.023 14.4 0.7 0.27 11.0 0.2 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KLO14358.1 - 0.024 14.9 2.6 0.078 13.2 0.1 2.6 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 KLO14358.1 - 0.033 14.6 0.0 8.4 6.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 KLO14358.1 - 0.044 13.6 0.0 0.68 9.8 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Septin PF00735.18 KLO14358.1 - 0.1 11.8 0.0 9.9 5.3 0.0 2.2 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.18 KLO14358.1 - 0.6 9.4 1.9 20 4.5 0.1 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family ABC2_membrane_2 PF12679.7 KLO14358.1 - 4.7 6.4 15.0 0.051 12.9 5.3 2.6 3 0 0 3 3 3 0 ABC-2 family transporter protein DUF3176 PF11374.8 KLO14361.1 - 1.4e-06 28.5 2.3 2.7e-05 24.3 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) ThrE PF06738.12 KLO14361.1 - 0.013 14.9 0.4 0.67 9.3 0.2 2.6 2 0 0 2 2 2 0 Putative threonine/serine exporter CNV-Replicase_N PF16688.5 KLO14362.1 - 0.16 12.3 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Replicase polyprotein N-term from Coronavirus nsp1 Abhydrolase_1 PF00561.20 KLO14363.1 - 2e-20 73.6 0.0 1.3e-17 64.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO14363.1 - 4e-16 60.3 8.2 1.5e-14 55.1 8.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO14363.1 - 2.1e-11 43.5 0.0 6.5e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KLO14363.1 - 0.00029 19.8 0.0 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KLO14363.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase DLH PF01738.18 KLO14363.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 KLO14363.1 - 0.021 14.5 0.1 0.1 12.3 0.1 1.9 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 KLO14363.1 - 0.087 12.3 0.0 4.3 6.8 0.1 2.8 2 1 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 KLO14363.1 - 0.11 12.0 0.3 0.31 10.5 0.4 1.6 2 0 0 2 2 2 0 Esterase PHB depolymerase EHN PF06441.12 KLO14363.1 - 0.12 12.8 0.5 0.35 11.2 0.1 2.0 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Ndr PF03096.14 KLO14363.1 - 0.18 10.5 0.0 0.46 9.1 0.0 1.6 2 0 0 2 2 2 0 Ndr family Oxidored_FMN PF00724.20 KLO14364.1 - 5.6e-30 104.8 0.0 8.3e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase PF00069.25 KLO14368.1 - 4.3e-65 219.7 0.0 6.6e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO14368.1 - 2.1e-35 122.3 0.0 4e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KLO14368.1 - 0.0071 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KLO14368.1 - 0.0092 15.9 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fungal_KA1 PF16797.5 KLO14368.1 - 0.01 15.5 0.0 3.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Fungal kinase associated-1 domain F-box-like PF12937.7 KLO14369.1 - 0.0036 17.1 0.2 0.014 15.3 0.2 2.0 1 1 0 1 1 1 1 F-box-like DUF35_N PF12172.8 KLO14369.1 - 0.22 11.4 1.1 0.58 10.1 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) F-box-like PF12937.7 KLO14370.1 - 0.0013 18.6 1.1 0.0042 16.9 1.1 1.9 1 1 0 1 1 1 1 F-box-like zf-C3HC4_3 PF13920.6 KLO14371.1 - 1.2e-10 41.1 6.7 5.7e-09 35.7 2.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO14371.1 - 0.00023 20.9 1.6 0.00086 19.1 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO14371.1 - 0.00062 19.6 3.7 0.00062 19.6 3.7 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KLO14371.1 - 0.001 19.3 5.0 0.0043 17.3 1.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KLO14371.1 - 0.015 15.2 2.2 0.15 12.0 0.5 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KLO14371.1 - 1.9 8.6 6.3 11 6.2 1.0 2.6 2 0 0 2 2 2 0 RING-type zinc-finger 6PF2K PF01591.18 KLO14372.1 - 2.5e-62 210.1 0.0 3.4e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KLO14372.1 - 2.2e-24 86.2 0.1 1.5e-19 70.5 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KLO14372.1 - 1.4e-06 28.5 0.0 2.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KLO14372.1 - 4.3e-05 23.1 0.1 9e-05 22.0 0.1 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Toprim_3 PF13362.6 KLO14372.1 - 0.049 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Toprim domain tRNA_lig_kinase PF08303.11 KLO14372.1 - 0.089 12.9 0.0 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 tRNA ligase kinase domain MMR_HSR1 PF01926.23 KLO14375.1 - 5.9e-11 42.5 0.1 2.5e-10 40.5 0.0 2.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase MCM PF00493.23 KLO14375.1 - 0.0013 17.9 0.0 0.0096 15.0 0.0 2.0 2 0 0 2 2 2 1 MCM P-loop domain FeoB_N PF02421.18 KLO14375.1 - 0.0017 17.9 0.0 0.01 15.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KLO14375.1 - 0.0022 17.9 0.0 0.0052 16.7 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KLO14375.1 - 0.0049 17.3 0.1 0.016 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Ku_C PF03730.14 KLO14375.1 - 0.0056 17.4 2.1 3.6 8.3 0.0 2.3 2 0 0 2 2 2 2 Ku70/Ku80 C-terminal arm IIGP PF05049.13 KLO14375.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 KLO14375.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KLO14375.1 - 0.047 14.2 0.6 0.17 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 KLO14375.1 - 0.062 12.8 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 KLO14375.1 - 0.068 12.5 0.2 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 KLO14375.1 - 0.1 12.7 0.9 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 KLO14375.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein GTP_EFTU PF00009.27 KLO14375.1 - 0.28 10.7 0.4 7.8 6.0 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Peptidase_S10 PF00450.22 KLO14376.1 - 4.8e-106 355.7 0.0 6.3e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase FA_desaturase PF00487.24 KLO14377.1 - 3.2e-24 86.1 23.4 6.9e-24 85.0 23.4 1.5 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KLO14377.1 - 0.029 14.6 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) PAM2 PF07145.15 KLO14377.1 - 0.14 11.9 3.3 2.1 8.2 0.3 2.5 2 0 0 2 2 2 0 Ataxin-2 C-terminal region FA_desaturase PF00487.24 KLO14378.1 - 4.2e-24 85.8 27.5 7e-24 85.0 27.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KLO14378.1 - 0.0067 16.6 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Sec2p PF06428.11 KLO14382.1 - 9.8e-14 51.1 7.3 9.8e-14 51.1 7.3 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p CC2-LZ PF16516.5 KLO14382.1 - 0.18 12.2 7.6 1.3 9.5 1.4 3.0 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Fez1 PF06818.15 KLO14382.1 - 3.6 8.0 9.7 8.9 6.7 9.7 1.6 1 0 0 1 1 1 0 Fez1 CsbD PF05532.12 KLO14383.1 - 8.1e-05 22.4 2.1 0.004 17.0 0.8 2.6 2 1 0 2 2 2 2 CsbD-like CsbD PF05532.12 KLO14384.1 - 2.7e-05 24.0 0.5 9.9e-05 22.2 0.5 2.0 1 0 0 1 1 1 1 CsbD-like CsbD PF05532.12 KLO14385.1 - 0.0049 16.7 4.4 0.0049 16.7 4.4 1.9 2 0 0 2 2 2 1 CsbD-like TPR_10 PF13374.6 KLO14385.1 - 0.23 11.4 3.6 0.47 10.4 3.6 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_1 PF07690.16 KLO14386.1 - 1.3e-18 67.1 37.5 1.3e-18 67.1 37.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KLO14386.1 - 0.00091 17.9 17.4 0.0054 15.3 5.3 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 KLO14386.1 - 0.041 12.2 1.1 0.11 10.8 1.1 1.7 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1453 PF07301.11 KLO14386.1 - 0.38 10.8 11.1 0.58 10.2 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1453) DFP PF04127.15 KLO14388.1 - 7.7e-20 71.5 0.0 2.1e-11 44.0 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein HAD PF12710.7 KLO14388.1 - 0.015 15.7 0.1 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4378 PF14309.6 KLO14388.1 - 0.02 15.2 0.1 0.038 14.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Peptidase_C12 PF01088.21 KLO14388.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Oxidored_FMN PF00724.20 KLO14392.1 - 6.3e-29 101.3 0.0 8.9e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldo_ket_red PF00248.21 KLO14393.1 - 6e-46 157.0 0.1 5.1e-44 150.6 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PX PF00787.24 KLO14394.1 - 1.7e-19 69.8 0.0 5e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 KLO14394.1 - 1.1e-10 41.5 0.3 4.5e-09 36.1 0.3 2.3 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.28 KLO14394.1 - 2.2e-06 27.2 0.9 8.7e-06 25.3 0.1 2.4 2 1 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KLO14394.1 - 3.7e-05 23.3 0.0 8.7e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KLO14394.1 - 0.0026 17.6 0.1 0.0059 16.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4748 PF15932.5 KLO14395.1 - 3.6e-08 33.0 0.0 4.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) WD40 PF00400.32 KLO14398.1 - 6.5e-42 140.7 22.5 7.2e-10 39.3 0.1 11.7 13 0 0 13 13 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO14398.1 - 1.7e-25 89.2 0.0 0.026 14.8 0.0 9.5 3 2 7 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KLO14398.1 - 1.1e-19 70.7 0.0 1.8e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KLO14398.1 - 6.6e-10 38.5 3.6 0.36 9.7 0.0 6.9 4 3 2 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KLO14398.1 - 4e-07 30.1 1.1 0.15 11.9 0.1 4.6 2 2 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KLO14398.1 - 3.5e-05 23.3 0.0 0.094 12.0 0.0 4.7 6 0 0 6 6 6 1 WD40-like domain ELYS-bb PF16687.5 KLO14398.1 - 0.015 13.9 0.0 0.091 11.4 0.0 2.1 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Cytochrom_D1 PF02239.16 KLO14398.1 - 0.022 13.3 0.3 12 4.3 0.0 3.5 4 0 0 4 4 4 0 Cytochrome D1 heme domain DPPIV_N PF00930.21 KLO14398.1 - 0.031 13.1 0.0 0.19 10.5 0.0 2.3 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region IKI3 PF04762.12 KLO14398.1 - 0.049 11.6 0.0 6.4 4.6 0.0 3.1 3 1 0 3 3 3 0 IKI3 family PALB2_WD40 PF16756.5 KLO14398.1 - 0.056 12.4 0.0 9.8 5.0 0.0 3.0 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain RAB3GAP2_N PF14655.6 KLO14398.1 - 0.062 12.6 0.0 18 4.5 0.0 3.7 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2840 PF11000.8 KLO14399.1 - 0.062 13.1 0.0 0.069 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) F-box-like PF12937.7 KLO14400.1 - 3.5e-08 33.2 0.2 1.1e-07 31.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like FAD_binding_3 PF01494.19 KLO14402.1 - 1.7e-21 76.9 0.0 2.9e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KLO14402.1 - 0.0018 18.5 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KLO14402.1 - 0.0073 15.4 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 KLO14402.1 - 0.17 10.9 0.5 1.2 8.1 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KLO14402.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding RRM_1 PF00076.22 KLO14403.1 - 1.3e-11 44.1 0.1 1.2e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KLO14403.1 - 4.7e-08 33.5 0.7 8.8e-08 32.6 0.7 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 HicB-like_2 PF15970.5 KLO14403.1 - 0.076 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Mitoc_mL59 PF18126.1 KLO14404.1 - 7.3e-42 142.7 1.9 9.5e-42 142.4 1.9 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 ATG11 PF10377.9 KLO14405.1 - 6.6e-31 107.1 0.1 6.6e-31 107.1 0.1 2.6 3 0 0 3 3 3 1 Autophagy-related protein 11 Sugar_tr PF00083.24 KLO14406.1 - 1.2e-85 288.1 23.5 1.4e-85 287.9 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO14406.1 - 1.6e-28 99.6 49.5 1.2e-25 90.2 30.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 KLO14407.1 - 3.1e-07 30.2 0.2 9.3e-07 28.6 0.2 1.8 1 0 0 1 1 1 1 F-box-like Sdh5 PF03937.16 KLO14408.1 - 7.2e-29 99.6 0.5 9.8e-29 99.1 0.5 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Gly_transf_sug PF04488.15 KLO14409.1 - 4.8e-06 27.1 0.0 9.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KLO14409.1 - 0.082 12.3 0.8 0.16 11.4 0.8 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Ribosomal_S6e PF01092.19 KLO14410.1 - 6.4e-57 190.9 0.0 1.1e-56 190.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.12 KLO14411.1 - 1.4e-31 108.3 0.1 2.3e-31 107.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KLO14411.1 - 2.1e-12 47.1 0.3 3e-12 46.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 HTH_32 PF13565.6 KLO14411.1 - 0.0067 17.0 0.2 0.016 15.8 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain PAX PF00292.18 KLO14411.1 - 0.099 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain SMC_N PF02463.19 KLO14413.1 - 1e-54 185.3 28.1 2.3e-54 184.1 28.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KLO14413.1 - 6.7e-31 107.0 0.2 4.4e-30 104.4 0.1 2.6 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KLO14413.1 - 3.2e-14 53.4 5.5 3.9e-07 30.2 0.0 3.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KLO14413.1 - 1.9e-13 51.4 11.0 1.9e-13 51.4 11.0 6.9 2 2 2 4 4 1 1 AAA domain AAA_29 PF13555.6 KLO14413.1 - 4.3e-07 29.6 0.0 9.1e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 KLO14413.1 - 0.00076 18.5 7.4 0.00076 18.5 7.4 7.0 3 2 4 7 7 7 3 Spc7 kinetochore protein SbcCD_C PF13558.6 KLO14413.1 - 0.0028 17.9 0.0 0.012 15.8 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AlkA_N PF06029.11 KLO14413.1 - 0.025 14.8 0.2 0.99 9.7 0.0 3.1 2 0 0 2 2 2 0 AlkA N-terminal domain ABC_tran PF00005.27 KLO14413.1 - 0.029 14.9 0.0 0.029 14.9 0.0 6.0 5 1 0 5 5 4 0 ABC transporter AAA_13 PF13166.6 KLO14413.1 - 0.037 12.7 91.0 0.0073 15.0 12.6 6.3 4 2 2 6 6 6 0 AAA domain AAA_22 PF13401.6 KLO14413.1 - 6.7 7.0 7.5 38 4.5 0.0 4.0 4 1 0 4 4 4 0 AAA domain CortBP2 PF09727.9 KLO14414.1 - 0.014 15.4 0.3 0.015 15.2 0.3 1.1 1 0 0 1 1 1 0 Cortactin-binding protein-2 DUF4600 PF15372.6 KLO14414.1 - 0.09 13.2 2.4 0.1 13.1 0.9 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4600) Peptidase_S41 PF03572.18 KLO14415.1 - 2.1e-06 27.4 0.0 4.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S41 ADH_N PF08240.12 KLO14417.1 - 2.3e-29 101.4 0.8 5.9e-29 100.2 0.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO14417.1 - 3.3e-22 78.9 0.0 5.2e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KLO14417.1 - 5.6e-11 42.3 0.2 4.3e-08 32.9 0.2 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KLO14417.1 - 1.1e-05 26.4 0.0 2.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KLO14417.1 - 0.00072 18.9 0.1 0.0021 17.4 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KLO14417.1 - 0.033 13.6 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KLO14417.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.12 KLO14417.1 - 0.074 13.7 0.2 0.31 11.7 0.1 2.0 2 1 0 2 2 2 0 Methyltransferase domain p450 PF00067.22 KLO14423.1 - 8.3e-81 272.1 0.0 2.3e-80 270.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Plavaka PF18759.1 KLO14426.1 - 2.3e-106 355.7 0.0 4.3e-106 354.8 0.0 1.5 2 0 0 2 2 2 1 Plavaka transposase zf-C2H2 PF00096.26 KLO14426.1 - 0.017 15.5 1.0 0.017 15.5 1.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type A-2_8-polyST PF07388.11 KLO14426.1 - 0.038 12.6 0.0 0.056 12.0 0.0 1.1 1 0 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) LSM PF01423.22 KLO14428.1 - 5.9e-19 67.5 0.2 8.1e-19 67.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KLO14428.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Hfq protein PHD PF00628.29 KLO14429.1 - 1.3e-09 37.8 8.4 1.3e-09 37.8 8.4 1.9 2 0 0 2 2 2 1 PHD-finger PHD_4 PF16866.5 KLO14429.1 - 0.4 10.8 5.1 1 9.5 5.1 1.7 1 0 0 1 1 1 0 PHD-finger DLH PF01738.18 KLO14430.1 - 7.8e-20 71.4 0.0 1.1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 KLO14430.1 - 0.0035 17.0 0.0 0.0044 16.6 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Chlorophyllase PF07224.11 KLO14430.1 - 0.17 10.8 0.2 0.28 10.2 0.2 1.2 1 0 0 1 1 1 0 Chlorophyllase GTP_EFTU PF00009.27 KLO14431.1 - 4.7e-55 186.1 0.0 7e-55 185.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KLO14431.1 - 1.6e-43 147.6 0.1 4e-43 146.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KLO14431.1 - 9.3e-15 54.8 1.8 2.3e-14 53.5 1.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KLO14431.1 - 0.00083 19.4 0.1 0.02 15.0 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase 5HT_transport_N PF03491.13 KLO14431.1 - 0.027 14.7 0.0 0.065 13.4 0.0 1.6 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Semialdhyde_dhC PF02774.18 KLO14431.1 - 0.078 13.0 0.3 0.28 11.2 0.1 1.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain NIF3 PF01784.18 KLO14431.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) GTP_EFTU_D4 PF14578.6 KLO14431.1 - 0.1 12.5 4.0 0.075 13.0 0.8 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Pkinase PF00069.25 KLO14432.1 - 2.1e-36 125.7 0.0 4.4e-35 121.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO14432.1 - 1.1e-11 44.5 0.0 2.3e-10 40.2 0.0 2.8 3 1 0 3 3 3 1 Protein tyrosine kinase Ribosomal_L32e PF01655.18 KLO14433.1 - 6.3e-51 171.3 2.4 7.2e-51 171.1 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Memo PF01875.17 KLO14434.1 - 2e-72 243.6 0.0 2.3e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Cellulase PF00150.18 KLO14435.1 - 1.5e-11 44.3 0.5 2.3e-11 43.7 0.5 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.8 KLO14435.1 - 0.0086 15.7 0.4 0.054 13.0 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core Abhydrolase_1 PF00561.20 KLO14437.1 - 3.8e-18 66.1 0.2 2.5e-14 53.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO14437.1 - 4.1e-17 62.3 0.1 9e-13 48.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KLO14437.1 - 6.8e-09 36.7 0.0 3.1e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KLO14437.1 - 2.3e-05 24.1 1.3 0.03 13.9 0.4 3.0 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 KLO14437.1 - 0.00042 20.1 0.2 0.055 13.2 0.1 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 KLO14437.1 - 0.002 17.8 0.0 0.0036 17.0 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_2 PF01674.18 KLO14437.1 - 0.0033 17.0 0.1 0.0061 16.1 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 2) Peptidase_S9 PF00326.21 KLO14437.1 - 0.0051 16.3 0.0 0.03 13.8 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KLO14437.1 - 0.032 14.1 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KLO14437.1 - 0.033 14.0 0.3 2 8.2 0.1 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Elong_Iki1 PF10483.9 KLO14438.1 - 5.6e-18 65.5 0.0 8.6e-18 64.9 0.0 1.3 1 1 0 1 1 1 1 Elongator subunit Iki1 KH_1 PF00013.29 KLO14439.1 - 1.4e-42 143.4 11.5 8.3e-17 60.8 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KLO14439.1 - 2.3e-10 40.2 2.6 0.0031 17.4 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KLO14439.1 - 3.3e-10 39.6 8.5 0.0036 17.1 0.6 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KLO14439.1 - 0.00014 21.8 11.0 0.014 15.5 0.1 3.8 4 0 0 4 4 4 2 NusA-like KH domain MARVEL PF01284.23 KLO14440.1 - 7.8e-05 22.7 3.5 0.00011 22.2 3.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain MFS_1 PF07690.16 KLO14441.1 - 8.1e-22 77.6 23.5 8.1e-22 77.6 23.5 2.3 3 0 0 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO14441.1 - 0.00014 20.9 15.0 0.0036 16.2 15.3 3.0 1 1 1 2 2 2 1 Sugar (and other) transporter TssN PF17555.2 KLO14441.1 - 0.32 10.3 1.3 0.86 8.9 0.6 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF4381 PF14316.6 KLO14441.1 - 2.9 8.1 4.5 2 8.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) MutS_III PF05192.18 KLO14442.1 - 0.034 14.4 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 MutS domain III Spc7_N PF15402.6 KLO14442.1 - 0.051 11.8 0.4 0.065 11.5 0.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Phage_sheath_1C PF17482.2 KLO14442.1 - 0.13 12.3 0.1 7.9 6.5 0.0 2.2 1 1 1 2 2 2 0 Phage tail sheath C-terminal domain HEAT PF02985.22 KLO14443.1 - 1e-40 134.2 15.5 0.0018 18.4 0.0 12.7 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.6 KLO14443.1 - 1.6e-34 118.1 12.9 1.7e-10 41.1 0.0 7.6 2 2 5 7 7 7 6 HEAT repeats HEAT_EZ PF13513.6 KLO14443.1 - 2e-15 56.9 7.1 0.0012 19.2 0.2 7.5 6 2 2 8 8 8 4 HEAT-like repeat Cnd1 PF12717.7 KLO14443.1 - 5.3e-13 49.3 1.7 0.09 12.8 0.0 6.0 4 2 3 7 7 7 5 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KLO14443.1 - 1.9e-10 41.2 1.3 0.015 15.9 0.1 6.6 4 2 4 8 8 7 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KLO14443.1 - 2.2e-07 29.8 2.5 0.00071 18.3 0.0 3.2 2 1 1 3 3 3 2 Adaptin N terminal region Arm PF00514.23 KLO14443.1 - 0.00016 21.6 3.2 14 5.9 0.0 6.2 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat IFRD PF05004.13 KLO14443.1 - 0.0003 20.0 1.7 0.88 8.6 0.0 4.7 5 2 1 7 7 7 1 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 KLO14443.1 - 0.00075 19.1 0.1 5.2 6.6 0.1 3.9 2 2 2 4 4 4 2 CLASP N terminal HEAT_PBS PF03130.16 KLO14443.1 - 0.0015 19.1 2.7 0.67 10.8 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Tugs PF17840.1 KLO14443.1 - 0.12 12.6 0.6 0.76 10.0 0.3 2.5 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain TMEM154 PF15102.6 KLO14444.1 - 0.00064 19.6 0.2 0.00064 19.6 0.2 2.0 2 0 0 2 2 2 1 TMEM154 protein family DUF3377 PF11857.8 KLO14444.1 - 0.012 15.5 0.3 0.034 14.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) SKG6 PF08693.10 KLO14444.1 - 0.18 11.3 1.3 0.19 11.1 0.1 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DNA_pol_A_exo1 PF01612.20 KLO14445.1 - 2.8e-10 40.2 0.3 2.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease PHD PF00628.29 KLO14445.1 - 0.045 13.7 0.6 0.13 12.2 0.6 1.7 1 0 0 1 1 1 0 PHD-finger Glyco_transf_41 PF13844.6 KLO14446.1 - 8.7e-96 321.2 0.9 8.9e-45 153.0 0.1 3.2 2 1 0 3 3 3 3 Glycosyl transferase family 41 TPR_1 PF00515.28 KLO14446.1 - 8.6e-14 50.7 0.0 0.00083 19.1 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KLO14446.1 - 2.1e-10 39.9 0.0 0.012 15.8 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KLO14446.1 - 4.3e-10 39.1 0.2 0.032 14.1 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KLO14446.1 - 2.4e-09 36.7 0.0 0.00011 21.8 0.0 4.0 2 2 2 4 4 4 3 TPR repeat TPR_7 PF13176.6 KLO14446.1 - 3.8e-09 35.9 0.0 0.023 14.7 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO14446.1 - 2.1e-08 33.7 0.0 0.28 11.4 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KLO14446.1 - 3.9e-08 33.5 0.0 0.12 12.7 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KLO14446.1 - 3.5e-07 30.1 0.0 0.72 10.4 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KLO14446.1 - 2.7e-05 24.6 0.0 0.029 15.2 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KLO14446.1 - 6.1e-05 23.4 0.0 0.0035 17.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KLO14446.1 - 0.00042 20.9 0.0 0.0086 16.7 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat WD40 PF00400.32 KLO14448.1 - 0.61 11.1 13.6 7.3 7.6 0.0 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat TMEM135_C_rich PF15982.5 KLO14449.1 - 1.3e-06 29.1 1.0 2.6e-06 28.1 0.2 1.9 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 CCB1 PF12046.8 KLO14449.1 - 0.052 12.9 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B CBP_BcsF PF11120.8 KLO14449.1 - 0.068 13.3 0.1 0.31 11.2 0.1 2.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF Pex24p PF06398.11 KLO14450.1 - 3.8e-08 32.7 2.2 4.7e-08 32.4 2.2 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HSCB_C PF07743.13 KLO14451.1 - 2e-15 57.0 4.1 2.2e-15 56.9 2.9 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KLO14451.1 - 8.1e-05 22.7 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.7 KLO14451.1 - 0.015 15.3 0.8 0.027 14.5 0.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.9 KLO14451.1 - 0.021 14.9 2.9 0.039 14.0 2.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Zn_ribbon_17 PF17120.5 KLO14451.1 - 0.037 13.6 0.1 0.059 13.0 0.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF35_N PF12172.8 KLO14451.1 - 0.28 11.1 7.6 0.66 9.9 7.6 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HA2 PF04408.23 KLO14452.1 - 3.1e-16 59.6 0.0 7.6e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KLO14452.1 - 3.9e-14 52.9 0.0 3.3e-13 49.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain dsrm PF00035.26 KLO14452.1 - 1.9e-12 47.7 0.0 1.4e-05 25.7 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 KLO14452.1 - 2.7e-08 33.8 0.1 6.4e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KLO14452.1 - 2.4e-05 24.7 0.1 5.8e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 KLO14452.1 - 4.7e-05 23.7 0.0 0.00056 20.2 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ResIII PF04851.15 KLO14452.1 - 0.0034 17.4 0.0 0.037 14.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Arm-DNA-bind_1 PF09003.10 KLO14452.1 - 0.036 14.2 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage lambda integrase, Arm DNA-binding domain AAA_22 PF13401.6 KLO14452.1 - 0.11 12.7 0.2 0.7 10.2 0.1 2.4 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KLO14452.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Adaptin_N PF01602.20 KLO14453.1 - 1.1e-125 420.2 7.9 1.6e-125 419.7 7.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KLO14453.1 - 7.9e-37 125.9 0.0 1.7e-36 124.8 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KLO14453.1 - 5.4e-15 55.7 0.1 9.8e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 KLO14453.1 - 0.083 13.1 0.7 0.41 10.9 0.7 2.2 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KLO14453.1 - 0.1 12.9 0.3 1.7 9.1 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat RasGAP PF00616.19 KLO14454.1 - 1.2e-29 103.5 0.0 1.4e-25 90.2 0.0 2.7 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KLO14454.1 - 3.1e-07 30.6 0.0 6.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain ELO PF01151.18 KLO14455.1 - 2.8e-62 210.5 20.3 3.4e-62 210.2 20.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family VPS13_mid_rpt PF16910.5 KLO14457.1 - 1e-84 283.7 11.5 1.9e-84 282.8 4.1 3.6 2 1 1 3 3 3 1 Repeating coiled region of VPS13 SHR-BD PF06650.12 KLO14457.1 - 1.4e-70 237.7 0.0 1.7e-66 224.4 0.0 2.6 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 KLO14457.1 - 7.5e-67 225.6 8.2 9e-62 208.9 0.0 4.3 4 0 0 4 4 4 3 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KLO14457.1 - 7.4e-65 218.1 0.6 2.3e-59 200.1 0.0 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KLO14457.1 - 2.1e-31 108.4 0.0 7.3e-31 106.7 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KLO14457.1 - 4.5e-08 33.3 0.1 1.8e-07 31.4 0.1 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain DENN PF02141.21 KLO14458.1 - 7.8e-19 68.3 0.0 2.1e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 DENN (AEX-3) domain Lum_binding PF00677.17 KLO14458.1 - 0.1 12.6 0.1 0.59 10.2 0.0 2.4 2 0 0 2 2 2 0 Lumazine binding domain YabA PF06156.13 KLO14458.1 - 0.7 10.6 7.6 13 6.4 3.5 2.8 2 0 0 2 2 2 0 Initiation control protein YabA COG2 PF06148.11 KLO14458.1 - 1.1 9.4 9.1 0.85 9.7 5.2 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4618 PF15397.6 KLO14458.1 - 2.7 7.4 12.6 1.3 8.4 8.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) K-box PF01486.17 KLO14458.1 - 5.1 7.3 10.8 93 3.3 8.8 3.4 2 1 0 2 2 2 0 K-box region Mg_trans_NIPA PF05653.14 KLO14459.1 - 3.9e-18 65.6 16.6 1.5e-09 37.4 2.7 2.4 3 0 0 3 3 3 2 Magnesium transporter NIPA DUF2304 PF10066.9 KLO14459.1 - 1.9 8.7 6.5 0.58 10.4 2.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) EamA PF00892.20 KLO14459.1 - 2.3 8.4 32.5 0.86 9.8 11.0 3.3 3 1 0 3 3 3 0 EamA-like transporter family DUF373 PF04123.13 KLO14459.1 - 2.6 7.4 4.7 3.3 7.1 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) zf-CHCC PF10276.9 KLO14460.1 - 2.7e-13 49.7 0.8 3.9e-13 49.2 0.8 1.2 1 0 0 1 1 1 1 Zinc-finger domain Pkinase PF00069.25 KLO14462.1 - 2.9e-52 177.7 0.0 1e-51 175.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO14462.1 - 1.1e-22 80.6 0.0 2.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pribosyltran_N PF13793.6 KLO14463.1 - 7.9e-45 151.5 0.4 3.7e-42 142.9 0.1 2.2 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KLO14463.1 - 1.2e-38 133.0 1.0 9.2e-33 113.8 0.6 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KLO14463.1 - 7e-14 51.6 3.0 1.3e-13 50.8 0.4 2.4 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KLO14463.1 - 0.0053 16.2 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SDH_sah PF01972.16 KLO14463.1 - 0.092 11.7 0.1 0.69 8.9 0.0 2.0 2 0 0 2 2 2 0 Serine dehydrogenase proteinase DUF848 PF05852.11 KLO14463.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DCP2 PF05026.13 KLO14464.1 - 4.5e-26 91.0 5.2 7.6e-14 51.8 2.1 2.3 2 0 0 2 2 2 2 Dcp2, box A domain NUDIX PF00293.28 KLO14464.1 - 2.5e-16 59.9 0.0 5.8e-16 58.7 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain AAA_2 PF07724.14 KLO14465.1 - 6.4e-49 166.3 0.0 2.1e-46 158.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KLO14465.1 - 5.9e-33 112.9 2.0 5.9e-33 112.9 2.0 3.4 2 1 1 3 3 3 1 AAA lid domain ClpB_D2-small PF10431.9 KLO14465.1 - 2.3e-24 85.3 0.7 7.8e-24 83.6 0.1 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KLO14465.1 - 1.5e-23 83.6 0.0 1.1e-12 48.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KLO14465.1 - 2.1e-14 53.7 0.9 1.9e-07 31.1 0.0 4.0 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 KLO14465.1 - 2.4e-12 46.8 9.8 8.2e-11 41.9 0.7 4.0 4 0 0 4 4 3 1 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 KLO14465.1 - 6e-11 43.0 10.3 1.8e-06 28.5 0.0 4.9 4 2 1 6 6 4 2 AAA ATPase domain AAA_22 PF13401.6 KLO14465.1 - 1.2e-10 41.8 0.0 0.0022 18.3 0.0 4.3 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 KLO14465.1 - 1.1e-09 38.2 0.0 1.7e-05 24.6 0.0 3.3 3 1 0 3 3 3 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KLO14465.1 - 6.7e-07 29.2 0.0 0.00066 19.5 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KLO14465.1 - 1.8e-06 27.5 0.1 0.006 16.0 0.0 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KLO14465.1 - 4e-06 26.3 0.7 0.095 11.9 0.0 3.3 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_24 PF13479.6 KLO14465.1 - 2.7e-05 24.0 0.0 0.036 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KLO14465.1 - 7.8e-05 23.2 0.0 0.33 11.5 0.0 3.5 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KLO14465.1 - 0.00011 22.2 0.0 0.03 14.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 KLO14465.1 - 0.00012 22.3 0.0 0.18 11.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KLO14465.1 - 0.00017 21.4 0.4 2.3 8.0 0.0 4.3 5 0 0 5 5 4 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KLO14465.1 - 0.00024 21.4 0.1 1.8 9.0 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_7 PF12775.7 KLO14465.1 - 0.00065 19.3 0.0 1.5 8.3 0.0 2.5 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 KLO14465.1 - 0.00083 19.3 2.7 1.3 8.9 0.0 4.3 3 2 0 4 4 4 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KLO14465.1 - 0.0016 18.5 0.0 0.76 9.8 0.0 3.5 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KLO14465.1 - 0.0017 18.1 0.0 1.2 8.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 KLO14465.1 - 0.002 17.4 0.0 0.33 10.2 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 KLO14465.1 - 0.0034 17.4 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KLO14465.1 - 0.01 15.3 0.0 1.5 8.2 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein Roc PF08477.13 KLO14465.1 - 0.018 15.3 0.0 3 8.1 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KLO14465.1 - 0.019 15.2 2.2 3.5 7.8 0.0 3.4 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 KLO14465.1 - 0.028 15.0 3.2 4.9 7.7 0.0 3.7 4 0 0 4 4 3 0 ABC transporter ResIII PF04851.15 KLO14465.1 - 0.032 14.2 0.0 3 7.8 0.0 3.1 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KLO14465.1 - 0.034 14.5 1.5 5.6 7.3 0.1 3.9 4 1 0 4 4 4 0 AAA domain AAA_3 PF07726.11 KLO14465.1 - 0.065 13.1 0.1 44 4.0 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KLO14465.1 - 0.071 13.0 0.1 4.4 7.2 0.0 3.3 3 0 0 3 3 3 0 NTPase DUF5368 PF17336.2 KLO14465.1 - 0.09 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5368) CbiA PF01656.23 KLO14465.1 - 0.096 12.7 0.0 9.1 6.4 0.0 3.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Laminin_II PF06009.12 KLO14465.1 - 0.12 12.4 5.0 0.23 11.5 2.3 2.7 2 0 0 2 2 2 0 Laminin Domain II HTH_28 PF13518.6 KLO14465.1 - 0.13 12.5 1.7 0.5 10.5 0.0 3.0 4 0 0 4 4 2 0 Helix-turn-helix domain AAA_25 PF13481.6 KLO14465.1 - 0.27 10.8 4.4 2.9 7.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain Spc7 PF08317.11 KLO14465.1 - 0.35 9.7 8.9 0.78 8.6 8.9 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-C4H2 PF10146.9 KLO14465.1 - 0.76 10.0 6.3 1.7 8.9 6.3 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein SOAR PF16533.5 KLO14465.1 - 2.7 8.0 6.6 15 5.6 6.6 2.3 1 1 0 1 1 1 0 STIM1 Orai1-activating region DASH_Spc19 PF08287.11 KLO14465.1 - 6.7 6.6 13.0 16 5.4 8.1 2.5 1 1 1 2 2 2 0 Spc19 DUF402 PF04167.13 KLO14466.1 - 0.021 15.0 0.8 0.052 13.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF402) Xpo1 PF08389.12 KLO14467.1 - 2.6e-21 76.3 0.3 6.6e-20 71.7 0.0 3.0 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KLO14467.1 - 6.4e-07 29.2 0.1 5.8e-06 26.1 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KLO14467.1 - 0.087 13.2 0.2 3.5 8.1 0.0 3.8 5 0 0 5 5 5 0 HEAT repeats SQHop_cyclase_C PF13243.6 KLO14467.1 - 0.093 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain CoA_binding PF02629.19 KLO14468.1 - 9.6e-30 103.1 0.1 2.2e-29 102.0 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 KLO14468.1 - 1.9e-23 83.0 0.0 2.9e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KLO14468.1 - 1.1e-09 38.3 0.0 3.6e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KLO14468.1 - 8.8e-06 26.2 0.2 8.6e-05 23.0 0.0 2.5 3 1 0 3 3 3 1 CoA binding domain GFO_IDH_MocA PF01408.22 KLO14468.1 - 0.028 15.3 0.0 0.29 12.0 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NTPase_1 PF03266.15 KLO14468.1 - 0.044 13.7 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 NTPase ACBP PF00887.19 KLO14469.1 - 1.6e-20 73.1 0.0 3.1e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.6 KLO14469.1 - 4.9e-12 46.1 0.1 3.8e-06 27.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KLO14469.1 - 1.3e-10 41.7 0.0 2.1e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KLO14469.1 - 1.1e-08 35.1 0.0 2.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KLO14469.1 - 1.3e-08 34.9 0.5 6.4e-08 32.7 0.0 2.4 3 1 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KLO14469.1 - 5.7e-07 29.4 0.0 6.5e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat CP12 PF02672.15 KLO14469.1 - 0.32 11.8 1.9 0.34 11.7 0.2 2.0 2 1 0 2 2 2 0 CP12 domain Ribosomal_S16 PF00886.19 KLO14470.1 - 3.3e-22 78.3 0.1 4.5e-22 77.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 LSM PF01423.22 KLO14471.1 - 1.1e-21 76.3 0.1 1.2e-21 76.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain Arm PF00514.23 KLO14472.1 - 1.5e-92 301.2 14.7 3.5e-13 49.1 0.1 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KLO14472.1 - 1e-24 86.8 0.9 2.2e-24 85.7 0.9 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 KLO14472.1 - 1.7e-23 82.7 6.3 3.5e-09 37.0 0.1 5.9 4 2 1 5 5 5 5 HEAT-like repeat Arm_3 PF16186.5 KLO14472.1 - 1.7e-22 78.7 0.4 4.2e-22 77.5 0.4 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 KLO14472.1 - 7.9e-19 67.8 0.1 1.2e-06 28.8 0.0 5.2 1 1 3 5 5 5 4 HEAT repeats HEAT PF02985.22 KLO14472.1 - 2.8e-16 58.2 0.5 3.6e-05 23.7 0.0 6.9 6 0 0 6 6 6 3 HEAT repeat Adaptin_N PF01602.20 KLO14472.1 - 9.2e-10 37.7 0.0 5.2e-05 22.0 0.0 2.8 1 1 2 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.13 KLO14472.1 - 1.1e-06 28.4 0.0 0.042 13.3 0.0 3.8 2 1 2 4 4 4 2 Armadillo-like RICTOR_V PF14668.6 KLO14472.1 - 7.7e-06 26.1 1.2 0.18 12.0 0.0 4.5 4 2 1 6 6 5 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 KLO14472.1 - 1.3e-05 25.3 0.1 0.15 12.2 0.0 4.2 3 3 2 5 5 5 2 V-ATPase subunit H Cnd1 PF12717.7 KLO14472.1 - 0.0002 21.4 0.0 1.5 8.8 0.0 3.4 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KLO14472.1 - 0.0018 18.7 4.2 0.75 10.6 0.1 4.6 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 KLO14472.1 - 0.0024 17.3 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 Mo25-like CTNNBL PF08216.11 KLO14472.1 - 0.0026 17.9 0.1 12 6.1 0.0 4.1 5 0 0 5 5 4 0 Catenin-beta-like, Arm-motif containing nuclear DCB PF16213.5 KLO14472.1 - 0.035 13.8 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 V-ATPase_H_N PF03224.14 KLO14472.1 - 0.047 13.0 0.0 1.6 8.0 0.0 2.7 1 1 0 2 2 2 0 V-ATPase subunit H Fungal_trans PF04082.18 KLO14473.1 - 1e-13 51.0 0.4 1.5e-13 50.4 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO14473.1 - 3.5e-06 27.0 12.2 6.9e-06 26.1 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDT PF00800.18 KLO14474.1 - 4.8e-52 176.4 0.1 6.3e-52 176.0 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydratase p450 PF00067.22 KLO14475.1 - 9.5e-67 225.7 0.0 1.1e-66 225.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KLO14477.1 - 1.3e-08 34.2 0.0 2.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO14477.1 - 9e-06 25.7 11.1 1.6e-05 24.9 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0047 PF01894.17 KLO14478.1 - 6.6e-39 132.6 0.1 7.7e-39 132.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 TTL PF03133.15 KLO14479.1 - 5.9e-50 170.1 0.0 8e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family MMM1 PF10296.9 KLO14480.1 - 7.8e-34 117.2 0.1 4.3e-14 52.3 0.0 3.0 1 1 2 3 3 3 3 Maintenance of mitochondrial morphology protein 1 RNA_pol_Rpb8 PF03870.15 KLO14481.1 - 2.1e-48 164.0 0.2 2.6e-48 163.8 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KLO14481.1 - 0.016 15.3 0.1 0.58 10.2 0.1 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase, subunit G Con-6 PF10346.9 KLO14482.1 - 5.2e-35 119.2 4.1 8e-18 64.2 0.4 2.1 2 0 0 2 2 2 2 Conidiation protein 6 RelB PF04221.12 KLO14482.1 - 0.078 13.0 0.0 8.1 6.5 0.0 2.2 2 0 0 2 2 2 0 RelB antitoxin Con-6 PF10346.9 KLO14483.1 - 6.9e-30 102.8 7.4 1.9e-14 53.4 0.7 2.1 2 0 0 2 2 2 2 Conidiation protein 6 Acp26Ab PF05777.12 KLO14483.1 - 0.31 11.7 1.7 1.6 9.4 1.1 1.8 1 1 1 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) INCENP_ARK-bind PF03941.15 KLO14484.1 - 5.7e-19 67.8 2.1 5.7e-19 67.8 2.1 3.7 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region DDRGK PF09756.9 KLO14484.1 - 9.8 5.7 27.4 31 4.1 27.4 1.8 1 0 0 1 1 1 0 DDRGK domain TPR_12 PF13424.6 KLO14485.1 - 9.4e-14 51.5 0.1 1.7e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-MYND PF01753.18 KLO14485.1 - 3.3e-09 36.7 5.1 5e-09 36.1 5.1 1.3 1 0 0 1 1 1 1 MYND finger TPR_10 PF13374.6 KLO14485.1 - 5.2e-08 32.5 0.9 0.00028 20.7 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KLO14485.1 - 6.7e-07 28.9 0.1 0.0037 17.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO14485.1 - 1.4e-05 24.8 0.1 0.24 11.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KLO14485.1 - 2.6e-05 23.9 0.2 0.21 11.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KLO14485.1 - 0.0011 19.0 0.4 0.062 13.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KLO14485.1 - 0.0088 16.6 0.0 1.7 9.5 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KLO14485.1 - 0.022 15.4 2.1 6 7.6 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KLO14485.1 - 0.045 14.6 1.9 5.8 8.0 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO14485.1 - 0.049 13.0 0.1 0.06 12.7 0.1 1.1 1 0 0 1 1 1 0 MalT-like TPR region TPR_19 PF14559.6 KLO14485.1 - 0.085 13.4 0.8 0.42 11.2 0.7 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Ecl1 PF12855.7 KLO14485.1 - 0.17 13.0 2.3 0.26 12.4 2.3 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins TPR_12 PF13424.6 KLO14486.1 - 4.9e-14 52.4 6.2 4.5e-13 49.3 2.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KLO14486.1 - 3.8e-11 42.5 10.1 4.8e-05 23.1 0.6 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-MYND PF01753.18 KLO14486.1 - 4.7e-09 36.2 9.2 4.7e-09 36.2 9.2 1.6 2 0 0 2 2 2 1 MYND finger TPR_1 PF00515.28 KLO14486.1 - 2.1e-06 27.3 1.2 0.056 13.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KLO14486.1 - 9.9e-06 25.6 1.7 1.6 9.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO14486.1 - 0.00026 20.9 4.4 0.2 11.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KLO14486.1 - 0.0022 17.9 5.4 0.22 11.6 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KLO14486.1 - 0.0027 17.8 0.7 0.23 11.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KLO14486.1 - 0.0035 17.8 1.0 3.2 8.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO14486.1 - 0.012 15.0 1.5 0.015 14.7 1.5 1.1 1 0 0 1 1 1 0 MalT-like TPR region TPR_14 PF13428.6 KLO14486.1 - 3 8.9 5.7 31 5.7 0.2 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KLO14487.1 - 6.3e-14 52.0 8.3 5.7e-12 45.8 4.5 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KLO14487.1 - 1.1e-10 41.1 11.9 9.1e-05 22.2 1.7 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-MYND PF01753.18 KLO14487.1 - 4.6e-09 36.2 7.9 8.3e-09 35.4 7.9 1.5 1 0 0 1 1 1 1 MYND finger TPR_1 PF00515.28 KLO14487.1 - 4.2e-06 26.3 2.2 0.033 14.0 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO14487.1 - 1.1e-05 25.1 5.2 0.045 13.9 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KLO14487.1 - 4.3e-05 23.4 1.6 0.0086 16.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KLO14487.1 - 4.9e-05 23.1 5.4 0.048 13.7 0.2 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KLO14487.1 - 0.0005 20.3 2.5 1 9.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KLO14487.1 - 0.0016 18.9 1.3 2.4 9.0 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO14487.1 - 0.0054 16.1 3.2 0.007 15.8 3.2 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 KLO14487.1 - 0.058 14.2 6.4 3.8 8.6 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KLO14487.1 - 0.37 11.3 7.8 1.3 9.6 2.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KLO14487.1 - 1.2 9.8 7.8 11 6.8 0.2 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat Septin PF00735.18 KLO14488.1 - 6.4e-122 406.2 0.2 6.4e-122 406.2 0.2 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KLO14488.1 - 3.1e-08 33.7 0.3 9.5e-08 32.1 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO14488.1 - 7.9e-08 32.4 0.1 1.7e-05 24.8 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KLO14488.1 - 8.7e-05 22.1 1.5 0.003 17.1 0.0 2.8 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KLO14488.1 - 0.00034 20.9 0.0 0.0028 17.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KLO14488.1 - 0.00061 20.3 4.0 0.0035 17.9 0.3 2.6 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.16 KLO14488.1 - 0.00082 18.8 0.0 0.0024 17.2 0.0 1.8 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 KLO14488.1 - 0.0032 17.1 0.1 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 KLO14488.1 - 0.011 16.1 0.1 0.038 14.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 KLO14488.1 - 0.018 14.8 0.0 8.2 6.2 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KLO14488.1 - 0.047 13.7 5.0 0.075 13.1 0.2 3.0 2 1 0 2 2 2 0 Dynamin family AAA_29 PF13555.6 KLO14488.1 - 0.05 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KLO14488.1 - 0.061 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KLO14488.1 - 0.1 12.3 0.0 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Strep_SA_rep PF06696.11 KLO14488.1 - 0.11 12.6 0.2 0.11 12.6 0.2 2.0 2 0 0 2 2 1 0 Streptococcal surface antigen repeat ATP_bind_1 PF03029.17 KLO14488.1 - 1.1 8.9 3.8 9.1 6.0 0.0 2.8 3 1 0 4 4 4 0 Conserved hypothetical ATP binding protein RCDG1 PF15725.5 KLO14489.1 - 5.3 7.5 9.0 0.25 11.8 2.9 1.9 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein CN_hydrolase PF00795.22 KLO14490.1 - 6.6e-56 189.5 0.0 7.9e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MRP-S28 PF10213.9 KLO14491.1 - 6.4e-27 94.5 0.0 8.8e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF866 PF05907.13 KLO14492.1 - 2.9e-53 179.9 0.1 3.3e-53 179.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.6 KLO14492.1 - 0.014 15.4 0.5 0.021 14.8 0.5 1.3 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Zn-ribbon_8 PF09723.10 KLO14492.1 - 0.015 15.4 1.3 0.11 12.6 0.3 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.15 KLO14492.1 - 0.019 15.0 0.1 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 BED zinc finger DUF4379 PF14311.6 KLO14492.1 - 2.1 8.8 5.8 5.7 7.4 0.2 3.0 2 1 1 3 3 3 0 Probable Zinc-ribbon domain IQ PF00612.27 KLO14493.1 - 0.0078 15.9 0.0 0.0078 15.9 0.0 2.0 2 0 0 2 2 2 1 IQ calmodulin-binding motif Pkinase PF00069.25 KLO14494.1 - 5.7e-64 216.0 0.0 9.4e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO14494.1 - 1.9e-44 151.9 0.0 3.2e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO14494.1 - 2.8e-08 33.4 0.0 4.8e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Ras_bdg_2 PF14847.6 KLO14494.1 - 0.0053 17.1 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kdo PF06293.14 KLO14494.1 - 0.02 14.2 0.1 0.044 13.1 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KLO14494.1 - 0.057 12.2 0.0 0.16 10.7 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KLO14494.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family CLTH PF10607.9 KLO14495.1 - 8.3e-33 113.4 0.0 1.5e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Rrp15p PF07890.12 KLO14495.1 - 6.4e-26 91.3 0.3 6.4e-26 91.3 0.3 2.0 2 0 0 2 2 2 1 Rrp15p LisH PF08513.11 KLO14495.1 - 6.1e-09 35.5 1.6 7.5e-09 35.2 0.3 1.9 2 0 0 2 2 2 1 LisH Ndc1_Nup PF09531.10 KLO14495.1 - 0.19 10.4 5.2 0.29 9.8 5.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DIL PF01843.19 KLO14496.1 - 8.1e-27 93.5 0.1 1.9e-26 92.3 0.1 1.7 1 0 0 1 1 1 1 DIL domain Ank_4 PF13637.6 KLO14496.1 - 2.1e-08 34.5 0.6 6.2e-06 26.7 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KLO14496.1 - 1.6e-05 25.4 0.0 6e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KLO14496.1 - 3.1e-05 24.2 0.1 0.00034 20.9 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KLO14496.1 - 3.2e-05 24.2 1.6 0.11 13.0 0.4 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KLO14496.1 - 7.5e-05 22.8 0.7 0.0035 17.7 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat PAPA-1 PF04795.12 KLO14496.1 - 0.049 14.4 0.0 2.7 8.9 0.0 2.7 2 0 0 2 2 2 0 PAPA-1-like conserved region SnoaL PF07366.12 KLO14497.1 - 8.1e-06 25.7 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KLO14497.1 - 0.00053 20.6 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain Rhomboid PF01694.22 KLO14498.1 - 9.9e-34 116.5 16.3 9.9e-34 116.5 16.3 1.8 1 1 1 2 2 2 1 Rhomboid family PAC3 PF10178.9 KLO14500.1 - 4.2e-05 23.6 0.1 9.1e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 Proteasome assembly chaperone 3 Cut8 PF08559.10 KLO14501.1 - 5.9e-14 52.3 0.8 3.6e-13 49.7 0.8 2.2 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein SPX PF03105.19 KLO14503.1 - 0.8 9.6 2.7 1 9.2 2.7 1.2 1 0 0 1 1 1 0 SPX domain AT_hook PF02178.19 KLO14504.1 - 0.13 12.2 0.3 0.13 12.2 0.3 2.5 2 0 0 2 2 2 0 AT hook motif CKAP2_C PF15297.6 KLO14504.1 - 0.19 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus KDZ PF18758.1 KLO14505.1 - 2.7e-51 174.3 0.0 4.6e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO14505.1 - 3.2e-36 123.8 1.0 1.3e-35 121.8 0.2 2.4 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases DUF746 PF05344.11 KLO14505.1 - 0.13 12.1 0.1 0.81 9.6 0.0 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF746) Ham1p_like PF01725.16 KLO14506.1 - 3.7e-57 193.3 0.0 4.2e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF4827 PF16109.5 KLO14506.1 - 0.1 12.6 0.2 0.68 9.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4827) Rab5ip PF07019.12 KLO14507.1 - 3e-20 72.6 3.5 3.6e-20 72.3 3.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) TPR_17 PF13431.6 KLO14509.1 - 1.1e-09 38.0 0.0 0.015 15.6 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KLO14509.1 - 4.7e-09 35.7 0.0 0.31 10.9 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO14509.1 - 1.9e-08 33.8 6.5 0.097 12.8 0.0 6.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KLO14509.1 - 4.4e-08 32.7 0.0 0.046 13.4 0.0 4.4 4 1 1 5 5 5 2 TPR repeat TPR_14 PF13428.6 KLO14509.1 - 7.7e-05 23.2 8.2 3.2 8.8 0.0 6.6 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KLO14509.1 - 0.00013 22.6 4.7 0.078 13.6 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KLO14509.1 - 0.00026 20.9 0.0 24 5.5 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KLO14509.1 - 0.00026 21.2 6.0 3.5 8.0 0.0 5.4 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KLO14509.1 - 0.0046 17.4 0.0 50 4.5 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KLO14509.1 - 0.0084 15.9 8.3 16 5.6 0.0 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat Rnk_N PF14760.6 KLO14509.1 - 0.28 11.7 1.5 78 3.9 0.1 3.7 3 0 0 3 3 3 0 Rnk N-terminus TPR_9 PF13371.6 KLO14509.1 - 0.41 10.8 0.0 0.41 10.8 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat PH PF00169.29 KLO14510.1 - 1.4e-13 51.3 0.1 3.1e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 KLO14510.1 - 3.3e-13 49.2 0.1 6.6e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KLO14510.1 - 4e-12 45.6 0.3 8.4e-12 44.5 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 KLO14510.1 - 1.8e-08 34.3 0.0 3.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KLO14510.1 - 2.3e-08 33.6 0.0 4.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 KLO14510.1 - 3.5e-07 30.5 0.0 8.1e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KLO14510.1 - 0.097 12.9 0.2 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_3 PF18016.1 KLO14510.1 - 0.18 11.6 0.1 0.39 10.6 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SMC_N PF02463.19 KLO14511.1 - 7.6e-18 64.7 14.7 5.1e-17 62.0 14.7 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KLO14511.1 - 1.2e-11 45.5 23.0 1.2e-11 45.5 23.0 5.4 4 2 0 4 4 4 1 AAA domain AAA_25 PF13481.6 KLO14511.1 - 0.0076 15.8 0.7 1.8 8.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KLO14511.1 - 0.016 14.9 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 KLO14511.1 - 0.029 14.0 0.0 0.029 14.0 0.0 4.2 5 0 0 5 5 5 0 AAA domain ABC_tran PF00005.27 KLO14511.1 - 0.12 12.9 0.1 0.12 12.9 0.1 4.3 3 2 1 4 4 4 0 ABC transporter AAA_21 PF13304.6 KLO14511.1 - 0.14 12.0 0.0 0.14 12.0 0.0 3.2 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system RNase_PH PF01138.21 KLO14512.1 - 2.1e-26 93.0 0.0 4e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KLO14512.1 - 1.9e-08 34.2 0.0 3.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 UAF_Rrn10 PF05234.11 KLO14513.1 - 0.039 14.2 0.0 4 7.7 0.0 2.4 2 0 0 2 2 2 0 UAF complex subunit Rrn10 PNRC PF15365.6 KLO14513.1 - 0.46 10.4 2.2 1 9.3 2.2 1.6 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif Ribosomal_L13 PF00572.18 KLO14514.1 - 5.5e-52 175.3 0.1 6.9e-52 174.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Pkinase PF00069.25 KLO14515.1 - 7.6e-62 209.0 0.0 9.2e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO14515.1 - 1e-28 100.3 0.0 1.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KLO14515.1 - 0.0025 17.5 0.1 0.35 10.4 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KLO14515.1 - 0.02 13.9 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KLO14515.1 - 0.079 12.3 0.1 0.15 11.4 0.1 1.4 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 KLO14515.1 - 0.11 12.4 0.6 0.73 9.7 0.0 2.4 2 1 0 3 3 3 0 Phosphotransferase enzyme family NCOA_u2 PF16665.5 KLO14515.1 - 0.31 11.4 4.5 0.61 10.4 4.5 1.4 1 0 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein Pkinase PF00069.25 KLO14516.1 - 2.6e-64 217.1 0.0 3.2e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO14516.1 - 1.6e-28 99.7 0.0 4.4e-28 98.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KLO14516.1 - 0.004 16.8 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KLO14516.1 - 0.0075 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KLO14516.1 - 0.024 14.0 0.0 0.058 12.7 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KLO14516.1 - 0.046 12.5 0.0 0.087 11.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase F-box-like PF12937.7 KLO14517.1 - 9.4e-07 28.6 0.0 1e-05 25.3 0.0 2.9 2 0 0 2 2 2 1 F-box-like Peptidase_M24 PF00557.24 KLO14520.1 - 5.1e-51 173.3 0.0 5.9e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Nup188 PF10487.9 KLO14521.1 - 5.9e-55 186.7 0.0 6e-39 133.7 0.0 3.2 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 KLO14521.1 - 0.00011 21.2 0.1 0.00023 20.1 0.1 1.5 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Semialdhyde_dhC PF02774.18 KLO14522.1 - 2.5e-33 115.7 0.0 4.6e-33 114.8 0.0 1.4 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KLO14522.1 - 2.4e-28 99.0 0.0 3.6e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KLO14522.1 - 0.023 15.4 0.0 0.06 14.1 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TAF4 PF05236.14 KLO14523.1 - 1.7e-30 106.8 6.8 2.8e-30 106.0 6.8 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family zf_CCCH_4 PF18345.1 KLO14524.1 - 0.0001 22.2 4.7 0.00021 21.2 4.7 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KLO14524.1 - 0.00066 19.4 2.7 0.0011 18.7 2.7 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Nucleoporin_FG PF13634.6 KLO14524.1 - 0.013 16.3 113.0 0.11 13.4 31.8 6.1 2 1 3 5 5 5 0 Nucleoporin FG repeat region zf-CCCH PF00642.24 KLO14524.1 - 0.077 12.9 1.7 0.13 12.2 1.7 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4878 PF12870.7 KLO14524.1 - 0.14 12.4 0.9 0.26 11.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) FAM194 PF14977.6 KLO14525.1 - 0.082 12.2 0.0 0.57 9.5 0.0 1.9 2 0 0 2 2 2 0 FAM194 protein zf-CCHC PF00098.23 KLO14526.1 - 4.4e-31 105.5 55.8 1.9e-07 30.9 3.1 7.2 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 KLO14526.1 - 4e-07 29.9 34.3 0.048 13.6 0.6 6.2 3 1 3 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.6 KLO14526.1 - 7.8e-07 28.7 38.5 0.031 14.0 0.3 6.4 6 1 0 6 6 6 6 Zinc knuckle zf-CCHC_5 PF14787.6 KLO14526.1 - 0.013 15.2 37.5 0.038 13.7 0.9 6.0 6 1 1 7 7 7 0 GAG-polyprotein viral zinc-finger DUF1356 PF07092.12 KLO14526.1 - 1.1 8.5 4.3 4.3 6.5 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1356) Polyketide_cyc PF03364.20 KLO14527.1 - 7.4e-22 78.0 0.0 9.5e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltr_RsmB-F PF01189.17 KLO14529.1 - 1.6e-76 256.4 0.0 2.5e-76 255.8 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KLO14529.1 - 3.5e-08 33.8 0.0 1.1e-07 32.2 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF PCMT PF01135.19 KLO14529.1 - 0.0039 17.0 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KLO14529.1 - 0.029 14.5 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Aminotran_1_2 PF00155.21 KLO14530.1 - 2e-17 63.5 0.0 1.3e-12 47.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Sua5_yciO_yrdC PF01300.18 KLO14531.1 - 2.5e-54 183.5 0.0 4.5e-54 182.6 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KLO14531.1 - 6.7e-29 101.2 0.0 9.9e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DEAD PF00270.29 KLO14532.1 - 8.9e-44 149.3 0.0 1.4e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO14532.1 - 1e-26 93.4 0.0 1.2e-25 90.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO14532.1 - 0.00045 20.3 0.0 0.00082 19.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_L14e PF01929.17 KLO14532.1 - 0.079 13.5 0.3 0.19 12.3 0.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L14 Helitron_like_N PF14214.6 KLO14533.1 - 8.6e-37 127.2 0.1 7.5e-36 124.1 0.1 2.2 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus UCH PF00443.29 KLO14535.1 - 2.3e-28 99.4 0.0 3.7e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KLO14535.1 - 5.8e-05 22.8 0.8 0.00063 19.4 0.8 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase COG7 PF10191.9 KLO14536.1 - 6.4e-62 209.9 0.4 1.2e-37 129.6 0.4 3.9 3 1 0 3 3 3 3 Golgi complex component 7 (COG7) Vps53_N PF04100.12 KLO14536.1 - 0.0073 15.3 0.5 0.015 14.3 0.5 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Leptin PF02024.15 KLO14536.1 - 0.083 12.7 2.3 3.2 7.5 1.3 2.6 2 0 0 2 2 2 0 Leptin GST_N PF02798.20 KLO14538.1 - 2.7e-17 62.9 0.0 5.8e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO14538.1 - 1.2e-11 44.6 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KLO14538.1 - 1.6e-11 44.4 0.0 2.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO14538.1 - 1.7e-08 34.6 0.0 3.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO14538.1 - 5.2e-07 29.6 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO14538.1 - 0.0003 20.9 0.0 0.00055 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KLO14539.1 - 1.4e-21 76.6 0.0 2.3e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KLO14539.1 - 2.5e-14 53.4 0.0 4.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO14539.1 - 6.7e-12 45.5 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO14539.1 - 5.4e-11 42.6 0.0 9.1e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KLO14539.1 - 1e-07 31.9 0.1 2.2e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO14539.1 - 0.001 19.2 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KLO14539.1 - 0.017 15.8 0.0 0.047 14.4 0.0 1.8 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain GST_N PF02798.20 KLO14541.1 - 1.2e-16 60.8 0.0 2.4e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KLO14541.1 - 5.8e-13 49.1 0.0 1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO14541.1 - 8.2e-12 45.2 0.0 1.7e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KLO14541.1 - 4.5e-07 30.1 0.0 8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO14541.1 - 6.1e-07 29.4 0.1 1.1e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO14541.1 - 0.00055 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 KLO14541.1 - 0.013 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF1912 PF08930.10 KLO14541.1 - 0.043 14.0 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) Thioredoxin_8 PF13905.6 KLO14541.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like GST_N PF02798.20 KLO14542.1 - 1e-13 51.4 0.0 1.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KLO14542.1 - 8e-12 45.4 0.0 1.4e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO14542.1 - 8.6e-10 38.7 0.0 2e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KLO14542.1 - 2.4e-08 34.1 0.0 4.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO14542.1 - 6.4e-06 26.1 0.7 5e-05 23.3 0.7 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO14542.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_M4_C PF02868.15 KLO14545.1 - 5.1e-37 127.3 0.1 6.9e-37 126.9 0.1 1.2 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 KLO14545.1 - 3.3e-24 86.1 0.7 3.3e-24 86.1 0.7 1.5 2 0 0 2 2 2 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 KLO14545.1 - 6.6e-05 22.5 0.1 0.00012 21.7 0.1 1.4 1 0 0 1 1 1 1 Protealysin propeptide F-box-like PF12937.7 KLO14546.1 - 9.3e-09 35.0 0.2 2.6e-08 33.6 0.2 1.8 1 0 0 1 1 1 1 F-box-like XPC-binding PF09280.11 KLO14546.1 - 0.015 15.0 0.1 0.22 11.3 0.0 2.5 2 0 0 2 2 2 0 XPC-binding domain F-box PF00646.33 KLO14546.1 - 0.21 11.5 2.7 6.1 6.9 0.0 2.9 2 0 0 2 2 2 0 F-box domain Tyrosinase PF00264.20 KLO14547.1 - 1.5e-48 166.1 0.8 2.5e-48 165.3 0.8 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KLO14547.1 - 1.7e-24 86.8 0.0 2.7e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Tyosinase_C PF18132.1 KLO14548.1 - 4.4e-17 62.9 0.0 5.5e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Tyosinase C-terminal domain Pkinase PF00069.25 KLO14549.1 - 2.2e-40 138.7 0.0 2.7e-20 72.9 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KLO14549.1 - 7.7e-12 45.0 0.0 6.5e-09 35.5 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KLO14549.1 - 0.039 13.9 0.2 0.039 13.9 0.2 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO14549.1 - 0.092 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KLO14549.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4862 PF16154.5 KLO14550.1 - 0.081 12.3 0.0 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4862) bPH_3 PF14470.6 KLO14550.1 - 0.15 12.4 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain Vps36_ESCRT-II PF11605.8 KLO14550.1 - 0.17 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 RRP7 PF12923.7 KLO14551.1 - 3.1e-31 108.0 9.0 3.1e-31 108.0 9.0 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KLO14551.1 - 9.6e-09 35.2 0.1 2.9e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 KLO14551.1 - 2.8e-05 23.9 0.0 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CPSF100_C PF13299.6 KLO14551.1 - 0.57 10.3 6.4 0.18 12.0 0.5 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal HEPN_AbiU2 PF18734.1 KLO14551.1 - 0.59 9.6 5.8 0.053 13.0 1.2 1.6 2 0 0 2 2 2 0 AbiU2 LZ_Tnp_IS66 PF13007.7 KLO14551.1 - 0.73 10.7 7.5 1.1 10.0 2.1 3.0 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain RTP1_C1 PF10363.9 KLO14553.1 - 2.6e-32 111.3 0.0 5.7e-31 107.0 0.0 3.0 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 KLO14553.1 - 0.00027 21.3 0.2 21 5.6 0.0 5.2 4 1 0 4 4 4 1 HEAT repeats RTP1_C2 PF10304.9 KLO14553.1 - 0.0099 15.6 0.4 0.023 14.4 0.4 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT PF02985.22 KLO14553.1 - 0.015 15.5 2.6 2.2 8.8 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 KLO14553.1 - 0.043 14.3 0.5 35 5.0 0.0 4.1 3 0 0 3 3 3 0 HEAT-like repeat Aldedh PF00171.22 KLO14554.1 - 7e-107 357.8 0.0 8.4e-107 357.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BTB PF00651.31 KLO14555.1 - 2.8e-10 40.4 0.0 4.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Hydrophobin PF01185.18 KLO14556.1 - 1.6e-24 86.3 9.6 2e-24 86.0 9.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KLO14557.1 - 1.1e-09 38.7 0.9 1.5e-09 38.4 0.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KLO14558.1 - 3.4e-27 94.9 11.9 4e-27 94.6 11.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.12 KLO14558.1 - 3.2 8.5 9.3 8.8 7.1 0.8 2.4 2 0 0 2 2 2 0 Ion channel inhibitory toxin Hydrophobin PF01185.18 KLO14560.1 - 5.8e-25 87.7 8.3 6.9e-25 87.5 8.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KLO14561.1 - 5e-12 46.3 8.4 6.4e-12 45.9 8.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KLO14562.1 - 3.1e-25 88.6 10.2 4.3e-25 88.2 10.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF2997 PF11211.8 KLO14562.1 - 0.74 9.6 2.7 4.7 7.1 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2997) Telomere_reg-2 PF10193.9 KLO14563.1 - 5.6e-34 116.9 0.3 1.7e-33 115.3 0.0 2.1 2 0 0 2 2 2 1 Telomere length regulation protein VCX_VCY PF15231.6 KLO14563.1 - 0.0094 16.6 0.2 0.029 15.1 0.2 1.8 1 0 0 1 1 1 1 Variable charge X/Y family Methyltransf_16 PF10294.9 KLO14564.1 - 1.4e-14 54.2 0.0 5.6e-09 36.0 0.1 3.2 2 1 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 KLO14564.1 - 0.21 11.2 0.0 0.65 9.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain HA2 PF04408.23 KLO14565.1 - 4.6e-23 81.6 1.8 2e-22 79.5 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KLO14565.1 - 3.2e-15 56.2 0.0 9e-15 54.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KLO14565.1 - 1.3e-07 31.6 0.0 3.2e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO14565.1 - 3.5e-07 30.5 0.0 9.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KLO14565.1 - 7.1e-06 26.3 0.3 2.6e-05 24.5 0.3 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KLO14565.1 - 9.4e-05 21.8 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KLO14565.1 - 0.0017 18.1 0.0 0.0045 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KLO14565.1 - 0.0033 16.5 0.0 0.012 14.7 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 KLO14565.1 - 0.0048 17.2 0.0 0.016 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KLO14565.1 - 0.0056 16.4 0.1 0.031 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KLO14565.1 - 0.028 13.8 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 KaiC ResIII PF04851.15 KLO14565.1 - 0.03 14.3 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KLO14565.1 - 0.034 14.2 0.1 0.21 11.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KLO14565.1 - 0.047 13.4 0.0 8.7 6.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Flavi_DEAD PF07652.14 KLO14565.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 KLO14565.1 - 0.057 13.9 0.1 0.26 11.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KLO14565.1 - 0.082 13.1 0.1 0.6 10.3 0.1 2.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KLO14565.1 - 0.1 13.0 0.3 0.37 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain LRR_4 PF12799.7 KLO14566.1 - 2.4e-12 46.8 1.6 0.34 11.4 0.0 7.3 4 2 4 9 9 9 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO14566.1 - 4.3e-11 42.5 3.8 1.2e-10 41.2 3.8 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KLO14566.1 - 1.2e-09 37.5 14.5 3.1 8.1 0.0 10.4 12 0 0 12 12 12 3 Leucine Rich repeat LRR_8 PF13855.6 KLO14566.1 - 0.01 15.6 2.5 19 5.1 0.0 4.6 6 1 1 7 7 7 0 Leucine rich repeat Preseq_ALAS PF09029.10 KLO14566.1 - 0.025 15.1 0.6 0.13 12.7 0.1 2.6 2 1 0 2 2 2 0 5-aminolevulinate synthase presequence SAM_Ste50p PF09235.10 KLO14566.1 - 6.9 7.0 7.9 22 5.4 0.1 4.3 4 1 1 5 5 5 0 Ste50p, sterile alpha motif DUF5310 PF17237.2 KLO14567.1 - 1.2e-20 73.1 5.5 1.2e-20 73.1 5.5 1.4 2 0 0 2 2 2 1 Family of unknown function (DUF5310) Telomere_res PF16684.5 KLO14571.1 - 0.032 13.7 0.2 0.039 13.4 0.2 1.1 1 0 0 1 1 1 0 Telomere resolvase RPE65 PF03055.15 KLO14572.1 - 0.051 12.8 0.1 0.065 12.4 0.1 1.2 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein ETX_MTX2 PF03318.13 KLO14572.1 - 0.072 12.8 1.8 0.89 9.3 0.3 2.2 2 0 0 2 2 2 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Shadoo PF14999.6 KLO14572.1 - 0.11 12.6 11.3 0.27 11.3 11.3 1.7 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective TFIIA PF03153.13 KLO14572.1 - 0.11 12.4 11.5 0.17 11.8 11.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2388 PF09498.10 KLO14572.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2388) YabA PF06156.13 KLO14572.1 - 1.4 9.6 7.8 2.3 8.9 0.4 2.6 2 0 0 2 2 2 0 Initiation control protein YabA Ribosomal_L37ae PF01780.19 KLO14573.1 - 2.1e-33 114.3 5.8 2.3e-33 114.1 5.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 KLO14573.1 - 0.0015 18.4 2.7 0.0022 18.0 2.7 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.15 KLO14573.1 - 0.0053 16.7 3.4 0.25 11.4 0.3 2.2 1 1 1 2 2 2 2 BED zinc finger zf-RING_13 PF17977.1 KLO14573.1 - 0.0064 16.6 2.5 0.0078 16.3 2.5 1.1 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Elf1 PF05129.13 KLO14573.1 - 0.056 13.5 2.4 0.079 13.0 2.4 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like NST1 PF13945.6 KLO14573.1 - 0.074 13.1 0.7 0.095 12.8 0.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator C1_2 PF03107.16 KLO14573.1 - 0.29 11.5 3.1 1.5 9.2 3.2 1.9 1 1 0 1 1 1 0 C1 domain A2L_zn_ribbon PF08792.10 KLO14573.1 - 0.34 10.7 4.0 1.3 8.9 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Rubredoxin_2 PF18073.1 KLO14573.1 - 0.96 9.2 5.2 5.9 6.7 5.2 2.0 1 1 0 1 1 1 0 Rubredoxin metal binding domain zf-Sec23_Sec24 PF04810.15 KLO14573.1 - 1.4 9.0 4.6 9 6.4 0.2 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.6 KLO14573.1 - 3.1 8.4 6.9 10 6.8 0.6 2.2 1 1 1 2 2 2 0 Zinc-finger double domain SlyX PF04102.12 KLO14574.1 - 0.013 16.1 0.5 0.21 12.2 0.1 2.6 2 0 0 2 2 2 0 SlyX Rx_N PF18052.1 KLO14574.1 - 0.16 12.2 0.7 5.2 7.4 0.0 3.6 5 0 0 5 5 5 0 Rx N-terminal domain Fib_alpha PF08702.10 KLO14574.1 - 0.42 10.8 2.6 1.9 8.7 0.2 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 KLO14574.1 - 5.3 7.0 7.3 7.3 6.5 0.1 3.4 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Plavaka PF18759.1 KLO14575.1 - 5.6e-70 236.1 0.0 7.7e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF4566 PF15130.6 KLO14575.1 - 0.098 12.1 0.1 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4566) ABC_tran PF00005.27 KLO14578.1 - 5.2e-35 120.9 0.0 1.2e-34 119.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KLO14578.1 - 4.1e-26 92.2 8.1 7.6e-26 91.4 8.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KLO14578.1 - 4e-06 26.4 0.5 4.3e-05 23.1 0.5 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KLO14578.1 - 0.00011 22.6 0.1 0.00046 20.6 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KLO14578.1 - 0.00096 19.0 0.1 0.0081 16.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KLO14578.1 - 0.0015 18.8 0.1 0.01 16.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KLO14578.1 - 0.0024 17.5 0.2 0.0064 16.2 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KLO14578.1 - 0.0077 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KLO14578.1 - 0.021 14.7 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 KLO14578.1 - 0.051 14.0 0.0 0.41 11.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 KLO14578.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit APS_kinase PF01583.20 KLO14578.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase FAST_2 PF08368.12 KLO14578.1 - 0.15 12.8 0.0 0.4 11.5 0.0 1.7 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 MTABC_N PF16185.5 KLO14578.1 - 0.29 10.6 0.0 0.29 10.6 0.0 2.8 4 0 0 4 4 4 0 Mitochondrial ABC-transporter N-terminal five TM region RRM_1 PF00076.22 KLO14579.1 - 1e-11 44.5 0.0 1.3e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KLO14579.1 - 0.18 11.4 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_71 PF03659.14 KLO14581.1 - 5.6e-124 413.8 9.1 6.5e-124 413.6 9.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_71 PF03659.14 KLO14582.1 - 2.8e-126 421.3 8.8 3.3e-126 421.1 8.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 NAD_kinase PF01513.21 KLO14583.1 - 1.1e-74 251.3 0.0 1.8e-74 250.6 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DUF3435 PF11917.8 KLO14583.1 - 0.049 12.6 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) 2OG-FeII_Oxy_3 PF13640.6 KLO14584.1 - 6.3e-07 30.2 0.1 2e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Fer2_BFD PF04324.15 KLO14584.1 - 0.0031 17.8 0.1 0.007 16.7 0.1 1.6 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain CCD PF07860.11 KLO14585.1 - 0.041 13.9 0.2 0.081 13.0 0.2 1.5 1 0 0 1 1 1 0 WisP family C-Terminal Region Fascin PF06268.13 KLO14585.1 - 0.046 13.9 0.2 1 9.6 0.0 2.5 2 0 0 2 2 2 0 Fascin domain DUF4859 PF16151.5 KLO14585.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) CE2_N PF17996.1 KLO14587.1 - 0.0005 20.0 0.0 0.93 9.5 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal CE2_N PF17996.1 KLO14588.1 - 0.048 13.6 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal DAP10 PF07213.11 KLO14589.1 - 0.031 14.2 0.4 0.085 12.8 0.4 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Macoilin PF09726.9 KLO14589.1 - 2 6.9 9.5 2.8 6.4 9.5 1.2 1 0 0 1 1 1 0 Macoilin family EphA2_TM PF14575.6 KLO14589.1 - 7 7.6 0.0 7 7.6 0.0 2.9 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mito_carr PF00153.27 KLO14590.1 - 1.6e-69 229.9 5.0 8.5e-25 86.5 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KLO14590.1 - 0.063 12.4 0.3 5.8 6.0 0.0 2.8 3 0 0 3 3 3 0 Gammaproteobacterial serine protease RhoGAP PF00620.27 KLO14591.1 - 5.6e-34 117.2 0.0 1.2e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF3533 PF12051.8 KLO14592.1 - 5.8e-100 334.9 16.3 7.7e-100 334.5 16.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) TIP39 PF14980.6 KLO14593.1 - 0.0084 16.0 1.5 0.015 15.1 1.5 1.4 1 0 0 1 1 1 1 TIP39 peptide EphA2_TM PF14575.6 KLO14593.1 - 0.058 14.3 0.0 0.62 11.0 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KLO14593.1 - 0.073 11.9 0.0 0.11 11.3 0.0 1.3 1 1 0 1 1 1 0 Amnionless Adeno_E3_CR2 PF02439.15 KLO14593.1 - 0.088 12.6 1.0 0.17 11.6 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Herpes_gE PF02480.16 KLO14593.1 - 0.099 11.4 0.1 0.23 10.2 0.1 1.5 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM51 PF15345.6 KLO14593.1 - 0.099 12.5 3.2 0.17 11.7 0.0 2.6 3 0 0 3 3 3 0 Transmembrane protein 51 DUF4514 PF14986.6 KLO14593.1 - 0.12 12.4 0.2 0.28 11.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Syndecan PF01034.20 KLO14593.1 - 0.2 11.6 0.1 0.37 10.8 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF4381 PF14316.6 KLO14593.1 - 0.22 11.8 0.2 0.34 11.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TP6A_N PF04406.14 KLO14594.1 - 1.7e-22 79.2 0.0 3.3e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase GTP_EFTU PF00009.27 KLO14595.1 - 4.3e-18 65.6 0.0 1.1e-17 64.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KLO14595.1 - 5.8e-06 26.6 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KLO14595.1 - 0.0081 16.5 0.8 0.039 14.4 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KLO14595.1 - 0.024 14.7 0.0 0.055 13.6 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KLO14595.1 - 0.11 12.2 0.5 3.8 7.3 0.1 2.9 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Glyco_hydro_18 PF00704.28 KLO14596.1 - 2.1e-82 277.4 0.1 2.7e-82 277.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ABC_tran PF00005.27 KLO14597.1 - 6.2e-47 159.6 0.0 2.2e-28 99.5 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KLO14597.1 - 8.4e-12 45.5 0.1 0.0078 16.1 0.1 3.8 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system Chromo PF00385.24 KLO14597.1 - 1.7e-11 43.9 0.4 3.1e-11 43.0 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SMC_N PF02463.19 KLO14597.1 - 5e-11 42.5 0.0 0.00014 21.4 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KLO14597.1 - 1.3e-07 32.0 0.3 0.0036 17.6 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KLO14597.1 - 1.3e-07 32.3 3.2 0.0036 17.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 KLO14597.1 - 2.3e-07 30.9 0.7 0.00015 21.7 0.0 3.8 4 0 0 4 4 4 1 NACHT domain AAA_29 PF13555.6 KLO14597.1 - 3e-06 26.9 1.6 0.059 13.1 0.2 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KLO14597.1 - 4.4e-06 26.8 0.0 0.0098 16.0 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KLO14597.1 - 9.6e-06 26.1 1.8 0.097 13.1 0.0 4.3 4 1 0 4 4 3 1 AAA ATPase domain AAA_18 PF13238.6 KLO14597.1 - 1.6e-05 25.4 0.0 0.11 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KLO14597.1 - 2.9e-05 24.4 0.0 0.25 11.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KLO14597.1 - 6.8e-05 22.8 0.0 0.05 13.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 KLO14597.1 - 7.3e-05 22.6 0.1 0.23 11.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_13 PF13166.6 KLO14597.1 - 0.00015 20.6 0.1 0.5 8.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 KLO14597.1 - 0.00024 21.5 0.0 0.69 10.3 0.0 3.4 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KLO14597.1 - 0.00052 20.0 1.9 10 6.1 0.0 4.3 5 0 0 5 5 3 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KLO14597.1 - 0.00068 19.8 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KLO14597.1 - 0.00097 19.2 0.1 1.3 9.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KLO14597.1 - 0.0013 19.1 0.1 2.4 8.6 0.0 2.9 2 0 0 2 2 2 1 RNA helicase PduV-EutP PF10662.9 KLO14597.1 - 0.0014 18.3 0.1 1.8 8.3 0.0 3.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KLO14597.1 - 0.0018 18.5 0.0 1.9 8.7 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KLO14597.1 - 0.002 17.9 3.5 1.5 8.5 0.0 4.0 4 1 0 4 4 2 2 AAA domain DUF87 PF01935.17 KLO14597.1 - 0.0024 18.0 2.3 1.9 8.5 0.1 3.7 5 0 0 5 5 3 1 Helicase HerA, central domain AAA_7 PF12775.7 KLO14597.1 - 0.0026 17.3 0.0 0.53 9.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 KLO14597.1 - 0.0028 17.3 0.9 1.6 8.3 0.0 2.9 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain Cnd1 PF12717.7 KLO14597.1 - 0.0037 17.3 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 ATP_bind_1 PF03029.17 KLO14597.1 - 0.0069 16.2 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 KLO14597.1 - 0.0071 16.3 0.2 1.1 9.1 0.0 3.1 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea SRPRB PF09439.10 KLO14597.1 - 0.0072 15.8 0.0 0.81 9.1 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 KLO14597.1 - 0.0073 15.5 0.0 1.2 8.2 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain CLASP_N PF12348.8 KLO14597.1 - 0.011 15.3 0.1 2.1 7.9 0.1 2.5 2 0 0 2 2 2 0 CLASP N terminal Arf PF00025.21 KLO14597.1 - 0.014 14.9 0.0 0.76 9.2 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_15 PF13175.6 KLO14597.1 - 0.015 15.1 0.1 2.2 7.9 0.3 2.3 2 0 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 KLO14597.1 - 0.015 14.6 0.1 0.67 9.1 0.0 2.9 3 0 0 3 3 3 0 KAP family P-loop domain AAA_27 PF13514.6 KLO14597.1 - 0.019 14.6 0.0 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KLO14597.1 - 0.021 14.1 0.2 3.9 6.7 0.1 3.1 3 0 0 3 3 3 0 Zeta toxin MeaB PF03308.16 KLO14597.1 - 0.021 13.8 0.8 0.34 9.8 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HEAT PF02985.22 KLO14597.1 - 0.028 14.6 5.6 16 6.1 0.0 4.4 4 0 0 4 4 3 0 HEAT repeat G-alpha PF00503.20 KLO14597.1 - 0.043 13.0 0.0 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit DUF3584 PF12128.8 KLO14597.1 - 0.044 11.3 1.3 3.3 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) MMS19_C PF12460.8 KLO14597.1 - 0.05 12.7 0.7 0.45 9.6 0.2 2.4 2 1 1 3 3 3 0 RNAPII transcription regulator C-terminal NTPase_1 PF03266.15 KLO14597.1 - 0.059 13.3 0.1 14 5.5 0.2 2.9 3 0 0 3 3 2 0 NTPase ATP-synt_ab PF00006.25 KLO14597.1 - 0.097 12.3 0.0 1.3 8.6 0.0 2.4 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.14 KLO14597.1 - 0.11 12.4 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.17 KLO14597.1 - 0.12 12.1 0.0 8.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Rad17 PF03215.15 KLO14597.1 - 0.12 12.3 0.1 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Dynamin_N PF00350.23 KLO14597.1 - 0.12 12.4 0.1 0.66 10.0 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Adeno_IVa2 PF02456.15 KLO14597.1 - 0.19 10.5 0.2 12 4.5 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein HEAT_EZ PF13513.6 KLO14597.1 - 0.26 11.8 6.1 86 3.8 0.1 5.0 5 0 0 5 5 4 0 HEAT-like repeat Adaptin_N PF01602.20 KLO14597.1 - 0.28 9.7 1.6 6.7 5.1 0.1 2.1 1 1 1 2 2 2 0 Adaptin N terminal region Homeodomain PF00046.29 KLO14598.1 - 6.3e-16 58.0 3.5 1.2e-15 57.1 3.5 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KLO14598.1 - 0.0023 17.8 0.1 0.0023 17.8 0.1 3.3 4 0 0 4 4 4 1 Homeobox KN domain Pkinase PF00069.25 KLO14599.1 - 3.4e-59 200.4 0.0 2e-38 132.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO14599.1 - 5.7e-24 84.8 0.0 5.2e-16 58.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KLO14599.1 - 1.1e-05 24.9 0.1 0.00069 19.0 0.0 2.9 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 KLO14599.1 - 0.0009 18.3 0.1 0.0013 17.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KLO14599.1 - 0.022 14.7 1.0 0.022 14.7 1.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO14599.1 - 0.061 12.1 0.5 0.087 11.6 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KLO14599.1 - 0.11 11.9 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KLO14599.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 KLO14599.1 - 0.2 10.6 0.2 0.3 10.0 0.2 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-C2H2 PF00096.26 KLO14600.1 - 2.8e-14 52.6 8.6 1.4e-07 31.5 1.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO14600.1 - 2.4e-10 40.3 6.9 1.5e-05 25.4 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KLO14600.1 - 3.1e-07 30.5 13.5 3.9e-05 23.9 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KLO14600.1 - 1.2e-05 25.4 0.5 1.2e-05 25.4 0.5 2.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KLO14600.1 - 3.7e-05 23.9 3.0 0.00012 22.4 0.5 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KLO14600.1 - 0.00021 21.2 4.2 0.0026 17.7 0.3 2.4 2 1 0 2 2 2 1 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KLO14600.1 - 0.0022 17.8 7.6 0.097 12.6 1.4 2.1 2 0 0 2 2 2 2 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KLO14600.1 - 0.0046 17.0 1.5 0.83 9.8 0.1 2.1 2 0 0 2 2 2 2 Zinc ribbon domain zf-C2HC_2 PF13913.6 KLO14600.1 - 0.0071 16.2 3.7 0.22 11.5 0.5 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-TRAF PF02176.18 KLO14600.1 - 0.019 15.6 2.4 0.036 14.7 2.4 1.5 1 1 0 1 1 1 0 TRAF-type zinc finger CCAP PF11105.8 KLO14600.1 - 0.019 14.9 0.7 0.019 14.9 0.7 1.1 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a zf-C2H2_11 PF16622.5 KLO14600.1 - 0.027 14.2 4.6 0.096 12.5 0.8 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KLO14600.1 - 0.039 14.3 1.2 0.16 12.4 0.1 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KLO14600.1 - 0.066 13.7 1.8 0.2 12.1 0.1 2.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 KLO14600.1 - 0.2 11.7 4.2 0.42 10.7 0.7 2.1 1 1 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.6 KLO14600.1 - 1.3 8.9 10.7 1.2 9.0 0.5 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain DUF1272 PF06906.11 KLO14600.1 - 4.8 7.4 8.5 2.1 8.5 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) BolA PF01722.18 KLO14602.1 - 5.5e-30 103.5 0.3 6.9e-30 103.1 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein Clr2_transil PF16761.5 KLO14603.1 - 4.5e-20 72.2 0.5 6.4e-20 71.7 0.5 1.2 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Pyrid_oxidase_2 PF13883.6 KLO14605.1 - 2.2e-27 96.1 0.0 3.1e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DNA_ligase_A_M PF01068.21 KLO14606.1 - 4e-41 140.9 0.0 1.2e-38 132.8 0.0 2.6 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KLO14606.1 - 6.2e-34 117.8 0.0 1.8e-33 116.3 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KLO14606.1 - 2.3e-17 63.4 0.0 6.5e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region zf-H2C2_2 PF13465.6 KLO14607.1 - 4.4e-08 33.2 2.3 5.8e-05 23.3 1.3 3.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KLO14607.1 - 6.1e-06 26.4 8.2 0.00082 19.7 2.6 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO14607.1 - 0.00018 22.1 7.1 0.003 18.2 2.0 4.3 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KLO14607.1 - 0.007 16.6 4.9 0.084 13.2 0.8 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KLO14607.1 - 0.077 12.8 0.6 0.077 12.8 0.6 3.2 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-met PF12874.7 KLO14607.1 - 0.085 13.3 0.1 0.085 13.3 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KLO14607.1 - 1.1 9.3 12.3 0.14 12.2 1.6 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger Acetyltransf_1 PF00583.25 KLO14608.1 - 2.1e-13 50.5 0.0 2.6e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KLO14608.1 - 8.7e-08 32.5 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO14608.1 - 8.3e-07 29.0 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KLO14608.1 - 0.0046 17.1 0.0 0.0054 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KLO14608.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO14608.1 - 0.024 14.6 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein dNK PF01712.19 KLO14608.1 - 0.032 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase Acetyltransf_3 PF13302.7 KLO14608.1 - 0.11 13.1 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KLO14610.1 - 1.6e-61 208.0 0.0 2.1e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO14610.1 - 2.8e-36 125.1 0.0 3.8e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO14610.1 - 4.5e-06 26.2 0.0 1.7e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO14610.1 - 0.00014 20.8 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO14610.1 - 0.061 12.7 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IU_nuc_hydro PF01156.19 KLO14611.1 - 4e-59 200.7 0.0 5.1e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ATP_transf PF09830.9 KLO14613.1 - 4.9e-22 77.9 0.0 8.1e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 KLO14613.1 - 0.0017 18.1 0.1 0.01 15.6 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4922) HIT PF01230.23 KLO14613.1 - 0.0071 17.1 0.0 0.091 13.5 0.0 2.4 2 1 0 2 2 2 1 HIT domain HicA_toxin PF07927.12 KLO14615.1 - 7.3e-07 29.1 0.0 1.8e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, NUP50 PF08911.11 KLO14616.1 - 2.6e-15 56.8 0.1 2.6e-15 56.8 0.1 4.2 4 1 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 KLO14616.1 - 8.1e-15 55.2 0.3 1.9e-14 54.0 0.3 1.6 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 KLO14616.1 - 0.033 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 WH1 domain RabGAP-TBC PF00566.18 KLO14617.1 - 3.2e-52 177.3 0.1 5.5e-52 176.5 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.6 KLO14617.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Interleukin 34 Cullin_binding PF03556.15 KLO14617.1 - 0.17 12.4 1.0 0.45 11.0 0.4 2.0 2 0 0 2 2 2 0 Cullin binding Ank_5 PF13857.6 KLO14619.1 - 1.3e-10 41.3 1.5 3.9e-06 27.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.24 KLO14619.1 - 3.9e-10 39.7 0.3 1.4e-08 34.7 0.2 2.7 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.7 KLO14619.1 - 1.2e-08 35.4 0.0 2.7e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KLO14619.1 - 4.3e-07 30.1 0.2 0.013 15.9 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KLO14619.1 - 4.8e-07 29.6 0.2 0.0027 18.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KLO14619.1 - 0.00016 22.1 0.2 0.00086 19.8 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) AAA_12 PF13087.6 KLO14620.1 - 1.5e-33 116.1 0.0 2.6e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KLO14620.1 - 2.7e-28 99.5 0.0 4.2e-14 53.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KLO14620.1 - 6.3e-09 35.8 0.2 1.2e-05 25.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KLO14620.1 - 3.7e-08 33.8 0.0 1.4e-05 25.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain zf_CCCH_4 PF18345.1 KLO14620.1 - 0.00068 19.6 4.7 0.00068 19.6 4.7 3.1 2 1 0 2 2 2 1 Zinc finger domain DUF2075 PF09848.9 KLO14620.1 - 0.0034 16.7 0.0 0.01 15.1 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KLO14620.1 - 0.013 15.5 0.0 0.038 14.0 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KLO14620.1 - 0.051 13.1 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ATPase PF06745.13 KLO14620.1 - 0.074 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC ETF PF01012.21 KLO14621.1 - 6.8e-35 120.6 3.8 1.2e-34 119.8 3.8 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KLO14621.1 - 5.2e-33 112.9 0.4 1.4e-32 111.5 0.4 1.8 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain TPR_1 PF00515.28 KLO14622.1 - 8.1e-16 57.1 0.3 0.00032 20.4 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KLO14622.1 - 2.9e-14 51.9 3.6 0.0012 18.8 0.1 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KLO14622.1 - 1.8e-11 43.3 0.3 0.013 15.7 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KLO14622.1 - 2.5e-11 44.0 0.6 1.5e-05 25.5 0.2 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KLO14622.1 - 3.3e-07 29.9 0.0 0.63 10.2 0.0 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KLO14622.1 - 9.1e-07 29.2 16.0 0.01 16.6 0.0 6.5 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KLO14622.1 - 6e-06 25.8 0.2 0.014 15.1 0.0 3.1 1 1 2 3 3 3 2 TPR repeat TPR_12 PF13424.6 KLO14622.1 - 9.6e-05 22.6 15.4 0.31 11.4 0.8 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KLO14622.1 - 0.00011 22.3 0.6 0.42 11.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KLO14622.1 - 0.00061 20.2 12.5 0.054 14.0 0.2 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KLO14622.1 - 0.0019 17.5 1.5 0.2 10.8 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KLO14622.1 - 0.0087 15.9 3.6 1.1 9.2 0.1 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KLO14622.1 - 0.064 12.7 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Coatomer epsilon subunit DUF1641 PF07849.11 KLO14622.1 - 0.14 12.1 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) ANAPC3 PF12895.7 KLO14622.1 - 0.29 11.4 1.1 7.6 6.8 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KLO14622.1 - 0.32 11.4 2.7 1.1 9.6 0.0 3.3 3 1 1 5 5 5 0 Tetratricopeptide repeat DJ-1_PfpI PF01965.24 KLO14623.1 - 1.5e-21 76.9 0.0 2.1e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KLO14623.1 - 0.19 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KLO14624.1 - 1.6e-22 80.0 0.0 2.3e-22 79.5 0.0 1.3 1 1 0 1 1 1 1 DJ-1/PfpI family Oxidored_q6 PF01058.22 KLO14624.1 - 0.0024 17.7 0.0 0.0078 16.0 0.0 1.7 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase, 20 Kd subunit ThiJ_like PF17124.5 KLO14624.1 - 0.021 14.6 0.0 0.039 13.6 0.0 1.4 1 1 0 1 1 1 0 ThiJ/PfpI family-like DUF3421 PF11901.8 KLO14626.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) EphA2_TM PF14575.6 KLO14626.1 - 0.048 14.5 0.2 0.3 12.0 0.0 2.2 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM237 PF15383.6 KLO14626.1 - 0.056 12.5 0.2 0.14 11.2 0.0 1.7 1 1 1 2 2 2 0 Transmembrane protein 237 RIFIN PF02009.16 KLO14626.1 - 0.16 11.9 1.5 1.4 8.8 0.0 2.0 2 0 0 2 2 2 0 Rifin FeoB_associated PF12669.7 KLO14626.1 - 0.38 11.2 1.2 0.96 9.9 1.2 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein ILVD_EDD PF00920.21 KLO14627.1 - 2.5e-203 676.4 0.0 2.9e-203 676.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family FAD_binding_3 PF01494.19 KLO14628.1 - 1.4e-19 70.6 0.0 3.6e-18 65.9 0.0 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KLO14628.1 - 6.6e-05 23.1 0.2 0.00028 21.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO14628.1 - 0.0026 17.4 0.4 0.01 15.5 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO14628.1 - 0.0096 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KLO14628.1 - 0.018 13.9 0.2 0.71 8.6 0.1 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 KLO14628.1 - 0.099 13.2 0.3 0.22 12.1 0.3 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF262 PF03235.14 KLO14629.1 - 3e-17 63.5 0.3 9.1e-17 62.0 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function DUF262 Dcc1 PF09724.9 KLO14630.1 - 4.8e-76 256.2 0.8 5.6e-76 256.0 0.8 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Zn_clus PF00172.18 KLO14632.1 - 1.5e-08 34.6 9.5 2.3e-08 34.0 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin PF08613.11 KLO14634.1 - 0.00018 21.9 0.0 0.0053 17.1 0.0 2.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KLO14634.1 - 0.056 13.2 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain FSA_C PF10479.9 KLO14639.1 - 1.8 6.6 10.0 2.5 6.1 10.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Git3 PF11710.8 KLO14640.1 - 1.1e-06 28.6 7.0 2.6e-06 27.3 7.0 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KLO14640.1 - 0.025 14.6 0.1 0.025 14.6 0.1 2.3 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Gpr1_Fun34_YaaH PF01184.19 KLO14640.1 - 0.031 13.9 1.9 4.2 6.9 0.3 2.3 2 0 0 2 2 2 0 GPR1/FUN34/yaaH family Peptidase_U4 PF03419.13 KLO14641.1 - 0.003 16.9 4.6 0.0036 16.7 4.6 1.1 1 0 0 1 1 1 1 Sporulation factor SpoIIGA PRA1 PF03208.19 KLO14641.1 - 0.075 12.7 3.5 0.11 12.1 2.7 1.6 1 1 0 1 1 1 0 PRA1 family protein CwsA PF10814.8 KLO14641.1 - 0.11 12.7 0.2 0.11 12.7 0.2 1.7 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA DUF420 PF04238.12 KLO14641.1 - 0.21 11.9 7.2 0.8 10.0 7.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF420) DUF4131 PF13567.6 KLO14641.1 - 1.2 8.8 7.1 0.82 9.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PTPS_related PF10131.9 KLO14641.1 - 3.2 6.0 8.2 8.7 4.5 7.8 1.7 1 1 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein YfhO PF09586.10 KLO14641.1 - 7.7 4.6 7.1 0.24 9.6 0.3 1.7 2 0 0 2 2 2 0 Bacterial membrane protein YfhO F-box-like PF12937.7 KLO14643.1 - 2.3e-06 27.4 0.2 7.2e-06 25.8 0.2 2.0 1 0 0 1 1 1 1 F-box-like Transferase PF02458.15 KLO14644.1 - 2.6e-12 46.1 0.0 4.6e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 Transferase family F-box-like PF12937.7 KLO14645.1 - 4.1e-05 23.4 0.1 0.0001 22.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO14646.1 - 1.3e-08 34.6 1.6 2e-08 34.0 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO14647.1 - 1.3e-05 25.0 0.1 3.1e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO14647.1 - 0.89 9.5 5.1 2.4 8.1 3.1 2.6 2 1 0 2 2 2 0 F-box domain HSP70 PF00012.20 KLO14648.1 - 2e-264 878.4 6.6 2.3e-264 878.2 6.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KLO14648.1 - 4.7e-16 58.5 0.1 8.2e-15 54.4 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KLO14648.1 - 0.0043 16.8 0.0 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KLO14648.1 - 0.0078 15.5 0.2 0.024 13.9 0.3 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase DUF4795 PF16043.5 KLO14648.1 - 0.052 13.1 5.1 0.33 10.5 4.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) B56 PF01603.20 KLO14649.1 - 2.1e-188 626.5 8.9 2.5e-188 626.2 8.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) SOG2 PF10428.9 KLO14651.1 - 3.9e-94 316.7 14.1 3.9e-94 316.7 14.1 3.8 4 1 0 4 4 4 1 RAM signalling pathway protein LRR_8 PF13855.6 KLO14651.1 - 3.8e-11 42.6 2.9 8.7e-05 22.2 0.1 3.3 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KLO14651.1 - 1.8e-08 34.6 0.0 0.00048 20.5 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KLO14651.1 - 0.0022 17.6 0.5 0.0043 16.6 0.5 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KLO14651.1 - 0.16 12.6 0.2 96 4.2 0.0 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat F-box-like PF12937.7 KLO14652.1 - 2.2e-09 37.0 1.1 8.5e-09 35.2 0.1 2.3 2 0 0 2 2 2 1 F-box-like DUF3510 PF12022.8 KLO14652.1 - 0.0039 17.6 0.3 0.0099 16.3 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) CdvA PF18822.1 KLO14652.1 - 0.043 13.6 0.4 0.1 12.4 0.4 1.6 1 0 0 1 1 1 0 CdvA-like coiled-coil domain F-box PF00646.33 KLO14652.1 - 0.12 12.2 0.9 0.48 10.4 0.1 2.4 2 1 0 2 2 2 0 F-box domain DUF3165 PF11364.8 KLO14653.1 - 0.03 14.6 1.0 0.042 14.2 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) TMEM52 PF14979.6 KLO14653.1 - 0.1 12.5 0.9 0.13 12.1 0.9 1.1 1 0 0 1 1 1 0 Transmembrane 52 Prominin PF05478.11 KLO14653.1 - 1.2 7.0 3.0 1.5 6.7 3.0 1.0 1 0 0 1 1 1 0 Prominin zf-C2H2_6 PF13912.6 KLO14654.1 - 0.004 17.1 0.1 0.0057 16.6 0.1 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KLO14654.1 - 0.0081 16.4 0.0 0.0088 16.3 0.0 1.1 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 KLO14654.1 - 0.022 15.5 1.6 0.056 14.3 1.3 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger HEPN_AbiU2 PF18734.1 KLO14654.1 - 0.04 13.4 0.1 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 AbiU2 F-box-like PF12937.7 KLO14655.1 - 0.00041 20.2 2.5 0.00051 19.9 0.5 2.4 2 0 0 2 2 2 1 F-box-like XTBD PF11952.8 KLO14655.1 - 0.041 13.6 0.0 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 XRN-Two Binding Domain, XTBD SRP54 PF00448.22 KLO14656.1 - 6e-73 244.7 1.4 1e-72 243.9 1.4 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KLO14656.1 - 1.8e-29 102.2 0.2 1.8e-29 102.2 0.2 4.4 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KLO14656.1 - 8.7e-20 70.7 2.7 2e-19 69.6 2.7 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KLO14656.1 - 8e-06 25.5 0.4 1.8e-05 24.4 0.4 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KLO14656.1 - 0.00021 21.5 0.1 0.00048 20.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KLO14656.1 - 0.00091 19.7 0.1 0.00091 19.7 0.1 3.0 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KLO14656.1 - 0.003 16.8 0.1 0.0059 15.9 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 KLO14656.1 - 0.0034 16.4 2.5 0.0099 14.9 0.1 2.6 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KLO14656.1 - 0.0085 16.1 0.0 0.043 13.9 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KLO14656.1 - 0.03 14.1 0.2 0.03 14.1 0.2 2.7 3 0 0 3 3 3 0 AAA domain SRPRB PF09439.10 KLO14656.1 - 0.052 13.0 1.6 4.9 6.5 0.9 2.7 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KLO14656.1 - 0.068 13.5 0.0 0.24 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KLO14656.1 - 0.092 12.8 0.4 0.39 10.8 0.2 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KLO14656.1 - 0.097 13.0 0.3 1 9.7 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain DUF5403 PF17395.2 KLO14656.1 - 0.46 10.8 3.7 1.6 9.1 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5403) DUF4227 PF14004.6 KLO14659.1 - 0.11 12.4 0.5 0.15 12.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) AA_permease_2 PF13520.6 KLO14661.1 - 1.1e-60 205.7 57.6 1.3e-60 205.4 57.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KLO14661.1 - 1.8e-16 59.9 49.2 2.4e-16 59.4 49.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KLO14662.1 - 8.6e-67 225.8 51.0 1.1e-66 225.5 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KLO14662.1 - 5.7e-17 61.5 43.2 7.9e-17 61.0 43.2 1.1 1 0 0 1 1 1 1 Amino acid permease LSM14 PF12701.7 KLO14663.1 - 3.3e-23 81.6 0.0 8.4e-23 80.3 0.0 1.7 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KLO14663.1 - 3e-08 34.5 2.7 3e-08 34.5 2.7 2.3 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KLO14663.1 - 0.00029 20.9 0.0 0.00061 19.9 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain TSA PF03249.13 KLO14663.1 - 0.13 11.0 3.9 0.19 10.5 3.9 1.3 1 0 0 1 1 1 0 Type specific antigen Macoilin PF09726.9 KLO14663.1 - 4.6 5.7 5.2 6.1 5.3 5.2 1.1 1 0 0 1 1 1 0 Macoilin family PhoLip_ATPase_C PF16212.5 KLO14664.1 - 1.1e-66 225.1 25.5 2.1e-66 224.2 25.5 1.5 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KLO14664.1 - 9.6e-21 73.3 1.3 1.9e-20 72.3 1.3 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KLO14664.1 - 1.4e-12 48.4 0.6 1.7e-05 25.2 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KLO14664.1 - 3.4e-09 36.6 0.0 2e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KLO14664.1 - 0.00014 21.4 1.8 0.00024 20.7 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KLO14664.1 - 0.002 17.9 0.5 0.0052 16.6 0.5 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMEM154 PF15102.6 KLO14665.1 - 0.0039 17.1 0.1 0.0065 16.4 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family ECSCR PF15820.5 KLO14665.1 - 0.095 12.5 0.7 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF4577 PF15145.6 KLO14665.1 - 0.75 9.8 2.3 0.47 10.5 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) zf-LITAF-like PF10601.9 KLO14665.1 - 8 6.8 9.8 3.4 8.0 0.3 2.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Hydrophobin PF01185.18 KLO14666.1 - 0.015 15.9 1.3 0.027 15.1 1.3 1.5 1 0 0 1 1 1 0 Fungal hydrophobin Pkinase_Tyr PF07714.17 KLO14673.1 - 6.2e-05 22.4 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO14673.1 - 0.00044 19.7 0.1 0.0016 17.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain DUF1730 PF08331.10 KLO14674.1 - 0.024 14.6 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1730) GRDP-like PF07173.12 KLO14675.1 - 2.2e-07 31.6 0.0 0.00012 22.7 0.0 2.3 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Lar_restr_allev PF14354.6 KLO14675.1 - 0.078 13.4 3.0 0.14 12.5 3.0 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar Sgf11 PF08209.11 KLO14675.1 - 0.61 9.7 3.2 0.42 10.2 0.6 1.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Sec66 PF09802.9 KLO14676.1 - 6.9e-48 162.6 0.0 8.7e-48 162.3 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SRP-alpha_N PF04086.13 KLO14676.1 - 2 8.3 12.4 2.4 8.0 12.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Rrn6 PF10214.9 KLO14676.1 - 5.7 5.3 12.4 6.8 5.0 12.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor USP7_ICP0_bdg PF12436.8 KLO14677.1 - 1.8e-86 289.4 4.9 8.6e-85 283.9 2.5 2.6 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KLO14677.1 - 2e-63 213.8 10.9 1.4e-62 211.1 0.9 3.7 3 1 1 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KLO14677.1 - 8.1e-53 179.5 0.3 1.5e-52 178.6 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KLO14677.1 - 4.2e-23 82.4 1.0 1.1e-22 81.1 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KLO14677.1 - 3.6e-07 30.3 0.0 1.7e-06 28.1 0.0 2.2 1 0 0 1 1 1 1 MATH domain Methyltransf_31 PF13847.6 KLO14679.1 - 7e-13 48.6 0.0 4.3e-12 46.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO14679.1 - 1.5e-12 47.7 0.0 4.3e-12 46.2 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO14679.1 - 2.4e-09 37.7 0.0 5.6e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO14679.1 - 1.1e-08 35.6 0.0 4.7e-08 33.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO14679.1 - 1.3e-07 32.3 0.0 4.3e-07 30.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KLO14679.1 - 0.00029 20.3 0.0 0.001 18.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase GidB PF02527.15 KLO14679.1 - 0.0021 17.4 0.0 0.35 10.2 0.0 2.2 2 0 0 2 2 2 2 rRNA small subunit methyltransferase G PrmA PF06325.13 KLO14679.1 - 0.0025 17.3 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KLO14679.1 - 0.012 15.2 0.0 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 KLO14679.1 - 0.054 13.6 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.10 KLO14679.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 KLO14679.1 - 0.2 10.9 0.0 1.6 8.0 0.0 2.3 3 0 0 3 3 3 0 O-methyltransferase domain Septin PF00735.18 KLO14680.1 - 1.6e-114 382.0 1.0 1.9e-114 381.7 1.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KLO14680.1 - 1.9e-08 34.4 0.1 4.1e-08 33.3 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KLO14680.1 - 1.5e-06 27.7 0.0 3.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KLO14680.1 - 2.8e-06 27.4 0.2 3.2e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KLO14680.1 - 2e-05 24.2 0.4 0.00032 20.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KLO14680.1 - 9.7e-05 22.5 0.4 0.11 12.5 0.2 2.4 1 1 1 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.18 KLO14680.1 - 0.0006 19.2 0.0 0.0014 18.0 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family ABC_tran PF00005.27 KLO14680.1 - 0.00066 20.2 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 KLO14680.1 - 0.00073 18.8 0.1 0.0015 17.7 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KLO14680.1 - 0.0027 18.1 0.0 0.0083 16.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KLO14680.1 - 0.0043 16.2 0.1 0.0078 15.3 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KLO14680.1 - 0.0064 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 KLO14680.1 - 0.01 15.2 0.1 0.092 12.1 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KLO14680.1 - 0.014 14.9 0.0 0.088 12.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 KLO14680.1 - 0.036 13.8 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 KLO14680.1 - 0.047 12.8 0.3 0.12 11.4 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 KLO14680.1 - 0.069 13.4 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KLO14680.1 - 0.071 12.7 0.1 0.25 10.9 0.0 1.9 2 1 0 2 2 2 0 Ras family AAA_14 PF13173.6 KLO14680.1 - 0.12 12.4 1.3 0.46 10.5 0.0 2.5 3 1 0 3 3 2 0 AAA domain Beta-lactamase PF00144.24 KLO14681.1 - 2.9e-41 141.8 0.0 4e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Aha1_N PF09229.11 KLO14682.1 - 3.5e-33 114.7 0.4 5.3e-33 114.1 0.4 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KLO14682.1 - 1.1e-16 61.2 0.1 3e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Tetraspanin PF00335.20 KLO14683.1 - 5.9e-09 36.0 11.2 8.3e-09 35.5 11.2 1.2 1 0 0 1 1 1 1 Tetraspanin family HTH_Tnp_Tc5 PF03221.16 KLO14684.1 - 0.03 14.3 0.1 3.5 7.7 0.0 2.7 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KLO14685.1 - 3.8e-17 62.5 0.0 5.2e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease ATP_sub_h PF10775.9 KLO14686.1 - 0.22 11.5 3.0 16 5.6 0.0 3.3 2 1 1 3 3 3 0 ATP synthase complex subunit h SoxE PF06525.11 KLO14687.1 - 0.085 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) domain TMP-TENI PF02581.17 KLO14687.1 - 0.15 11.4 0.0 0.37 10.1 0.0 1.6 1 1 1 2 2 2 0 Thiamine monophosphate synthase SMI1_KNR4 PF09346.10 KLO14689.1 - 5.9e-24 85.0 0.0 1.1e-23 84.1 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) HSA PF07529.13 KLO14690.1 - 2.5e-12 46.9 0.6 2.5e-12 46.9 0.6 3.9 5 0 0 5 5 5 1 HSA Myb_DNA-bind_6 PF13921.6 KLO14690.1 - 1.7e-06 28.1 0.7 5.1e-06 26.6 0.7 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KLO14690.1 - 7.6e-06 26.0 2.0 1.2e-05 25.4 0.5 2.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain 2OG-FeII_Oxy_2 PF13532.6 KLO14691.1 - 5e-23 82.3 0.0 6.5e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GRDP-like PF07173.12 KLO14692.1 - 1.4e-08 35.5 0.1 0.00013 22.7 0.0 2.4 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like FYVE PF01363.21 KLO14693.1 - 2.4e-17 62.8 1.1 4.5e-17 62.0 1.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 KLO14693.1 - 2e-16 59.4 1.2 4.5e-16 58.3 1.2 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2HC5 PF06221.13 KLO14693.1 - 0.011 15.8 4.8 0.011 15.8 4.8 1.8 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type FYVE_2 PF02318.16 KLO14693.1 - 0.33 11.2 2.5 0.48 10.7 0.2 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger SPX PF03105.19 KLO14694.1 - 5.2e-37 128.7 0.0 1.1e-36 127.7 0.0 1.5 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 KLO14694.1 - 1.6e-06 27.8 10.7 2.7e-06 27.1 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KLO14694.1 - 4.6e-06 26.7 11.0 2.8e-05 24.2 11.4 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KLO14694.1 - 2.8e-05 23.9 13.1 4.5e-05 23.2 13.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO14694.1 - 0.00013 22.2 13.4 0.00021 21.6 13.4 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KLO14694.1 - 0.0021 17.9 12.3 0.0037 17.1 12.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KLO14694.1 - 0.0045 16.9 12.6 0.008 16.1 12.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 KLO14694.1 - 0.0073 16.1 5.3 0.014 15.1 5.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KLO14694.1 - 0.0083 15.9 13.7 0.014 15.2 13.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO14694.1 - 0.027 14.5 13.4 0.054 13.5 13.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 KLO14694.1 - 0.11 12.4 5.4 0.21 11.5 5.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KLO14694.1 - 0.29 11.3 6.8 0.52 10.5 6.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_clus PF00172.18 KLO14695.1 - 0.0091 16.1 7.8 0.012 15.7 7.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO14696.1 - 0.12 12.5 9.8 0.26 11.4 9.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Swi3 PF07962.12 KLO14697.1 - 1.5e-25 89.0 0.1 2e-25 88.6 0.1 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Methyltransf_PK PF05891.12 KLO14698.1 - 2e-53 181.2 0.0 2.2e-51 174.5 0.0 2.2 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KLO14698.1 - 9e-05 23.1 0.0 0.12 13.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO14698.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO14698.1 - 0.0093 16.6 0.0 6.7 7.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KLO14698.1 - 0.034 14.9 0.0 0.33 11.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain SH2_2 PF14633.6 KLO14700.1 - 9.6e-72 240.9 0.4 9.6e-72 240.9 0.4 2.4 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 KLO14700.1 - 1.9e-28 98.8 0.0 5.8e-28 97.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 KLO14700.1 - 3.6e-28 98.3 1.1 5.7e-28 97.6 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 KLO14700.1 - 6e-27 94.3 0.0 1.3e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 KLO14700.1 - 9.4e-20 71.0 34.9 9.4e-20 71.0 34.9 4.5 6 0 0 6 6 6 2 Acidic N-terminal SPT6 HHH_9 PF17674.1 KLO14700.1 - 6e-07 30.3 1.3 7.7e-06 26.7 1.3 2.9 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 KLO14700.1 - 1.3e-06 28.4 0.0 4.8e-05 23.4 0.0 2.8 2 0 0 2 2 2 1 SH2 domain S1 PF00575.23 KLO14700.1 - 0.00013 22.2 1.8 0.0003 21.1 1.8 1.5 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.7 KLO14700.1 - 0.00042 20.5 0.1 0.0073 16.5 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif Tex_N PF09371.10 KLO14700.1 - 0.66 9.6 0.0 0.66 9.6 0.0 3.1 4 0 0 4 4 4 0 Tex-like protein N-terminal domain Epimerase PF01370.21 KLO14701.1 - 3e-09 36.7 0.0 1.5e-06 27.9 0.0 3.0 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KLO14701.1 - 3.2e-05 23.9 0.0 8.3e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KLO14701.1 - 0.0032 16.9 0.0 0.0063 16.0 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KLO14701.1 - 0.0062 16.0 0.0 0.013 15.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KLO14701.1 - 0.014 14.4 0.0 0.045 12.8 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KLO14701.1 - 0.063 12.4 0.0 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 KLO14701.1 - 0.15 11.6 0.0 0.74 9.3 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family DPBB_1 PF03330.18 KLO14702.1 - 2e-10 40.8 0.9 5.1e-10 39.5 0.1 2.1 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 KLO14702.1 - 0.00019 21.3 0.6 0.00049 19.9 0.6 1.7 1 0 0 1 1 1 1 Barwin family YL1 PF05764.13 KLO14702.1 - 0.15 12.1 7.8 0.21 11.7 7.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SWI-SNF_Ssr4 PF08549.10 KLO14702.1 - 0.25 9.9 15.7 0.31 9.6 15.7 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Apt1 PF10351.9 KLO14702.1 - 0.34 9.7 6.5 0.38 9.5 6.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SDA1 PF05285.12 KLO14702.1 - 0.47 9.8 13.7 0.63 9.4 13.7 1.1 1 0 0 1 1 1 0 SDA1 SOG2 PF10428.9 KLO14702.1 - 0.5 9.5 11.7 0.75 8.9 11.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein eIF3_subunit PF08597.10 KLO14702.1 - 1.1 9.2 11.1 1.5 8.7 11.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PBP1_TM PF14812.6 KLO14702.1 - 1.3 9.4 4.9 2.5 8.5 4.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KLO14702.1 - 2.1 7.6 9.3 3.3 7.0 9.3 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KLO14702.1 - 2.8 8.4 12.9 5.6 7.4 12.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 KLO14702.1 - 3.4 5.8 7.7 4.4 5.5 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 KLO14702.1 - 3.4 6.2 5.1 4.1 6.0 5.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 KLO14702.1 - 7 5.3 6.0 9.7 4.8 6.0 1.1 1 0 0 1 1 1 0 Presenilin SCAMP PF04144.13 KLO14703.1 - 8.2e-40 136.9 5.4 1e-39 136.6 5.4 1.1 1 0 0 1 1 1 1 SCAMP family Pox_A14 PF05767.12 KLO14703.1 - 0.32 11.2 2.3 0.76 10.0 0.4 2.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 RRM_1 PF00076.22 KLO14704.1 - 1.7e-80 264.8 5.9 2.5e-20 72.0 0.4 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KLO14704.1 - 8.4e-25 86.8 2.6 1.6e-24 85.8 1.4 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KLO14704.1 - 3.3e-11 42.9 0.0 0.013 15.1 0.1 4.2 1 1 3 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KLO14704.1 - 1.7e-05 24.8 0.2 1.5 9.0 0.1 4.7 4 1 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 KLO14704.1 - 2.9e-05 24.0 11.5 0.014 15.4 4.5 3.9 4 0 0 4 4 4 1 RNA binding motif RRM_occluded PF16842.5 KLO14704.1 - 0.00067 19.5 0.1 3.3 7.6 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KLO14704.1 - 0.028 14.4 1.0 22 5.2 0.0 3.8 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 KLO14704.1 - 0.068 12.9 3.1 9.7 6.0 0.3 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain DUF1919 PF08942.10 KLO14704.1 - 0.076 12.5 2.4 0.43 10.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1919) Thioesterase PF00975.20 KLO14704.1 - 0.13 12.3 0.2 0.23 11.5 0.2 1.4 1 0 0 1 1 1 0 Thioesterase domain Limkain-b1 PF11608.8 KLO14704.1 - 0.15 12.1 1.7 7.2 6.8 0.1 3.0 3 0 0 3 3 3 0 Limkain b1 PNPase PF03726.14 KLO14704.1 - 0.39 11.3 4.5 0.47 11.0 0.1 2.6 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF4407 PF14362.6 KLO14704.1 - 0.39 10.0 6.7 0.054 12.9 1.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Methyltransf_23 PF13489.6 KLO14705.1 - 5.6e-18 65.3 0.0 9.1e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO14705.1 - 9.8e-16 58.2 0.0 2.9e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO14705.1 - 1e-14 54.6 0.0 1.9e-13 50.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO14705.1 - 2e-14 54.0 0.0 4.2e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO14705.1 - 8.5e-09 36.1 0.0 7e-08 33.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO14705.1 - 4e-07 29.6 0.0 4.7e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KLO14705.1 - 5.5e-06 25.2 0.0 1.5e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 KLO14705.1 - 1.4e-05 24.7 0.0 0.0011 18.4 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 KLO14705.1 - 5.1e-05 23.2 0.0 0.00017 21.5 0.0 1.8 2 0 0 2 2 2 1 Hypothetical methyltransferase CMAS PF02353.20 KLO14705.1 - 0.00027 20.3 0.0 0.00061 19.2 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KLO14705.1 - 0.0051 16.4 0.0 0.0097 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KLO14705.1 - 0.015 14.6 0.0 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase domain DUF938 PF06080.12 KLO14705.1 - 0.034 13.9 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) WD40 PF00400.32 KLO14706.1 - 6.1e-07 30.0 4.3 0.001 19.9 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat DEAD PF00270.29 KLO14707.1 - 2.6e-06 27.3 0.2 2.8e-06 27.2 0.2 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO14707.1 - 0.015 15.3 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit adh_short PF00106.25 KLO14709.1 - 1.1e-48 165.3 0.1 1.6e-48 164.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO14709.1 - 2.2e-38 132.1 0.1 3.2e-38 131.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO14709.1 - 3.2e-14 53.2 0.2 5.3e-14 52.5 0.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KLO14709.1 - 0.00036 20.5 0.3 0.00065 19.6 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KLO14709.1 - 0.00082 19.3 0.1 0.0013 18.7 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 KLO14709.1 - 0.0073 16.9 0.2 0.018 15.6 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 KLO14709.1 - 0.0088 15.4 0.1 0.045 13.1 0.1 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 KLO14709.1 - 0.013 15.1 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Colicin PF01024.19 KLO14709.1 - 0.017 15.1 0.1 0.045 13.7 0.1 1.8 2 0 0 2 2 2 0 Colicin pore forming domain Sacchrp_dh_NADP PF03435.18 KLO14709.1 - 0.033 14.5 0.5 0.064 13.5 0.2 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KLO14709.1 - 0.034 14.2 0.6 0.13 12.3 0.3 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KLO14709.1 - 0.041 13.3 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KLO14710.1 - 5.1e-47 159.9 0.1 6.6e-47 159.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO14710.1 - 2.8e-35 122.0 0.0 4e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO14710.1 - 7.6e-11 42.2 0.2 1.1e-10 41.7 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.23 KLO14710.1 - 0.00045 20.2 0.1 0.00074 19.5 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KLO14710.1 - 0.0026 17.4 0.1 0.0041 16.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 KLO14710.1 - 0.0052 16.7 0.5 0.011 15.6 0.5 1.6 1 1 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 KLO14710.1 - 0.018 14.9 0.9 0.028 14.3 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KLO14710.1 - 0.042 13.2 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KLO14710.1 - 0.045 13.8 1.5 0.07 13.2 0.4 1.8 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KLO14711.1 - 8.3e-49 165.7 0.8 1.1e-48 165.3 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO14711.1 - 1.2e-35 123.2 0.4 1.6e-35 122.8 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO14711.1 - 5.5e-12 46.0 1.4 6.8e-12 45.7 0.6 1.4 2 0 0 2 2 2 1 KR domain ApbA PF02558.16 KLO14711.1 - 0.00012 21.8 0.1 0.00023 20.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 KLO14711.1 - 0.00078 19.4 0.9 0.00078 19.4 0.9 1.6 2 0 0 2 2 2 1 NAD(P)H-binding 3HCDH_N PF02737.18 KLO14711.1 - 0.0014 18.5 0.2 0.0026 17.7 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KLO14711.1 - 0.01 15.9 1.7 0.028 14.5 0.5 2.2 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 KLO14711.1 - 0.011 15.7 0.5 0.023 14.7 0.1 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GHMP_kinases_C PF08544.13 KLO14711.1 - 0.015 15.6 0.2 0.054 13.9 0.2 2.0 1 0 0 1 1 1 0 GHMP kinases C terminal THF_DHG_CYH_C PF02882.19 KLO14711.1 - 0.018 14.4 0.1 0.079 12.3 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 KLO14711.1 - 0.057 13.7 0.3 0.13 12.5 0.3 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KLO14712.1 - 1.2e-46 158.7 0.1 1.6e-46 158.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO14712.1 - 1.8e-35 122.6 0.1 2.3e-35 122.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO14712.1 - 6e-11 42.6 0.4 4.2e-10 39.8 0.1 2.1 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KLO14712.1 - 1.7e-06 28.0 0.2 4e-06 26.9 0.2 1.6 1 1 0 1 1 1 1 NAD(P)H-binding ApbA PF02558.16 KLO14712.1 - 4.4e-05 23.2 0.1 6.8e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KLO14712.1 - 0.00032 20.7 0.6 0.00051 20.1 0.1 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KLO14712.1 - 0.00081 19.3 1.5 0.0013 18.6 0.3 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KLO14712.1 - 0.0036 16.8 0.1 0.0053 16.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KLO14712.1 - 0.0097 16.0 1.9 0.016 15.3 0.7 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KLO14712.1 - 0.018 15.3 0.4 0.032 14.5 0.4 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KLO14712.1 - 0.027 13.6 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 KLO14712.1 - 0.03 13.6 0.2 0.1 11.9 0.1 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 KLO14712.1 - 0.041 13.7 0.1 0.082 12.7 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.19 KLO14712.1 - 0.044 13.1 0.0 0.087 12.2 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 KLO14712.1 - 0.048 13.2 1.4 0.71 9.4 0.8 2.2 2 0 0 2 2 2 0 NmrA-like family Wax2_C PF12076.8 KLO14712.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain F420_oxidored PF03807.17 KLO14712.1 - 0.14 12.8 1.2 0.32 11.6 0.3 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent COPIIcoated_ERV PF07970.12 KLO14713.1 - 7.3e-81 271.2 0.4 1e-80 270.7 0.4 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KLO14713.1 - 1.5e-26 92.6 0.3 1.5e-26 92.6 0.3 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) adh_short PF00106.25 KLO14714.1 - 2.8e-44 150.9 0.2 3.9e-44 150.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO14714.1 - 1.7e-32 112.9 0.2 2.4e-32 112.4 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO14714.1 - 4.5e-13 49.5 0.5 2e-12 47.4 0.2 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KLO14714.1 - 0.00058 19.4 0.0 0.0059 16.1 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KLO14714.1 - 0.00069 20.2 0.2 0.0019 18.7 0.2 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 KLO14714.1 - 0.0019 17.4 0.0 0.0025 17.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 KLO14714.1 - 0.0023 17.3 0.0 0.0051 16.1 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KLO14714.1 - 0.0047 17.0 0.1 0.0093 16.0 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DFP PF04127.15 KLO14714.1 - 0.021 14.7 0.5 0.046 13.6 0.5 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 KLO14714.1 - 0.022 14.7 0.4 0.022 14.7 0.4 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KLO14714.1 - 0.024 14.9 0.2 0.042 14.1 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KLO14714.1 - 0.029 14.8 0.1 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 KLO14714.1 - 0.034 13.8 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AstA PF04958.12 KLO14714.1 - 0.088 11.3 0.0 0.21 10.1 0.0 1.5 2 0 0 2 2 2 0 Arginine N-succinyltransferase beta subunit 2-Hacid_dh_C PF02826.19 KLO14714.1 - 0.096 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KLO14714.1 - 0.11 12.5 0.6 0.16 12.0 0.1 1.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4980 PF16352.5 KLO14714.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4980) adh_short PF00106.25 KLO14715.1 - 1.2e-48 165.2 0.1 1.5e-48 164.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO14715.1 - 2.2e-37 128.9 0.0 3e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO14715.1 - 1.8e-09 37.8 1.0 4.6e-09 36.5 0.3 1.8 2 0 0 2 2 2 1 KR domain ApbA PF02558.16 KLO14715.1 - 3.9e-05 23.3 0.2 6.9e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KLO14715.1 - 0.0014 18.7 1.8 0.0051 16.9 0.4 2.2 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KLO14715.1 - 0.0022 17.9 0.8 0.0053 16.7 0.8 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NAD_Gly3P_dh_N PF01210.23 KLO14715.1 - 0.0085 16.1 0.3 0.051 13.6 0.1 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KLO14715.1 - 0.015 15.9 1.2 0.026 15.1 0.3 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KLO14715.1 - 0.044 13.7 1.5 0.049 13.5 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KLO14715.1 - 0.11 11.8 0.8 0.35 10.2 0.2 2.1 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SIR2 PF02146.17 KLO14716.1 - 8.9e-62 208.1 0.0 2.3e-61 206.8 0.0 1.7 2 0 0 2 2 2 1 Sir2 family zinc_ribbon_15 PF17032.5 KLO14716.1 - 0.051 14.3 0.7 0.32 11.8 0.3 2.5 3 0 0 3 3 3 0 zinc-ribbon family pPIWI_RE_Y PF18156.1 KLO14716.1 - 0.13 12.7 0.7 5 7.5 0.0 2.5 2 0 0 2 2 2 0 pPIWI_RE three-gene island domain Y Sec1 PF00995.23 KLO14717.1 - 1.2e-124 417.7 0.0 1.3e-124 417.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Inj_translocase PF16928.5 KLO14717.1 - 0.18 11.3 0.0 8 5.9 0.0 2.5 2 1 1 3 3 3 0 DNA/protein translocase of phage P22 injectosome DUF727 PF05303.12 KLO14718.1 - 2.7e-09 37.0 0.0 3.2e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Aldo_ket_red PF00248.21 KLO14721.1 - 1.6e-39 135.9 0.0 2.4e-34 118.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family FYRN PF05964.14 KLO14722.1 - 1.4e-18 66.4 0.4 2.4e-18 65.7 0.4 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 KLO14722.1 - 8.2e-16 57.9 0.0 1.4e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 F/Y rich C-terminus DUF3915 PF13054.6 KLO14722.1 - 3.9 7.5 6.8 0.24 11.4 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) F-box-like PF12937.7 KLO14724.1 - 1.1e-11 44.5 2.6 1e-05 25.3 0.0 3.6 3 0 0 3 3 3 2 F-box-like F-box-like PF12937.7 KLO14725.1 - 5.1e-05 23.1 0.1 0.00028 20.7 0.0 2.4 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO14725.1 - 0.033 14.6 7.8 14 6.3 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) XPG_I PF00867.18 KLO14726.1 - 1.9e-14 53.8 0.0 4.3e-14 52.6 0.0 1.6 2 0 0 2 2 2 1 XPG I-region Phage_integrase PF00589.22 KLO14727.1 - 0.0013 18.6 0.0 0.025 14.4 0.0 2.7 2 1 0 2 2 2 1 Phage integrase family Peptidase_M66 PF10462.9 KLO14727.1 - 0.11 11.4 0.4 0.19 10.7 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 SUR7 PF06687.12 KLO14728.1 - 3.4e-13 49.7 13.0 4.8e-12 46.0 13.0 2.0 1 1 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 KLO14728.1 - 0.0034 16.9 1.5 0.0034 16.9 1.5 1.7 2 0 0 2 2 2 1 Clc-like DUF87 PF01935.17 KLO14728.1 - 0.05 13.7 0.9 0.071 13.2 0.9 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain DUF4383 PF14325.6 KLO14728.1 - 0.27 11.5 13.5 0.17 12.2 10.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) IQCJ-SCHIP1 PF15157.6 KLO14729.1 - 0.021 14.7 1.2 0.031 14.1 1.2 1.2 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Lipase_GDSL PF00657.22 KLO14732.1 - 2.3e-06 27.7 0.0 3.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KLO14732.1 - 2.4e-05 24.8 0.0 4.9e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SH3_9 PF14604.6 KLO14736.1 - 5e-07 29.5 0.0 9.3e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KLO14736.1 - 6.8e-06 25.6 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KLO14736.1 - 4.1e-05 23.2 0.0 8.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4381 PF14316.6 KLO14736.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Adaptin_binding PF10199.9 KLO14737.1 - 2.1e-11 44.5 0.5 7e-11 42.8 0.5 1.9 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 SNF5 PF04855.12 KLO14738.1 - 1.9e-71 240.6 0.0 4.8e-71 239.3 0.0 1.6 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Nucleo_P87 PF07267.11 KLO14738.1 - 7.3 5.3 6.0 11 4.7 6.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DNA_pol_B_thumb PF14791.6 KLO14739.1 - 1.1e-12 48.0 0.0 2.2e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KLO14739.1 - 3.5e-12 46.5 0.9 4.5e-11 43.0 0.2 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KLO14739.1 - 1.1e-09 38.0 0.0 2.7e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 KLO14739.1 - 4.8e-09 36.4 0.0 7.2e-08 32.6 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_5 PF14520.6 KLO14739.1 - 1.9e-06 28.4 0.1 9e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 KLO14739.1 - 0.00028 20.6 0.5 0.018 14.9 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif Cdd1 PF11731.8 KLO14739.1 - 0.042 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Pathogenicity locus HHH_2 PF12826.7 KLO14739.1 - 0.083 13.0 0.1 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF3176 PF11374.8 KLO14740.1 - 0.14 12.4 0.7 0.3 11.3 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) Q_salvage PF10343.9 KLO14741.1 - 2.5e-94 316.0 0.0 4e-94 315.3 0.0 1.3 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family adh_short PF00106.25 KLO14743.1 - 3.2e-44 150.8 1.2 5.1e-44 150.1 1.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO14743.1 - 2e-34 119.2 1.6 2.3e-34 119.0 1.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO14743.1 - 8.9e-11 42.0 0.5 1.7e-10 41.1 0.5 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KLO14743.1 - 0.0065 16.4 0.5 0.014 15.3 0.5 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KLO14743.1 - 0.009 15.3 0.2 0.044 13.1 0.0 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 KLO14743.1 - 0.023 14.4 0.1 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DFP PF04127.15 KLO14743.1 - 0.049 13.5 1.3 0.14 11.9 1.3 1.7 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.19 KLO14743.1 - 0.064 12.6 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KLO14743.1 - 0.095 12.8 0.3 2.4 8.2 0.0 2.7 2 1 1 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.6 KLO14743.1 - 0.15 12.0 1.4 0.27 11.1 1.4 1.6 1 1 0 1 1 1 0 NAD(P)H-binding DUF3176 PF11374.8 KLO14744.1 - 0.15 12.3 4.5 0.36 11.1 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3176) DUF3176 PF11374.8 KLO14745.1 - 0.0077 16.4 0.8 0.025 14.8 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF2723 PF11028.8 KLO14746.1 - 0.051 13.5 0.5 0.051 13.5 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) adh_short PF00106.25 KLO14747.1 - 1.4e-46 158.4 0.3 2e-46 157.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO14747.1 - 3.7e-32 111.8 0.2 4.6e-32 111.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO14747.1 - 5e-12 46.1 0.9 8.7e-12 45.3 0.5 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KLO14747.1 - 0.0012 18.7 1.0 0.0016 18.3 0.2 1.6 2 0 0 2 2 2 1 NAD(P)H-binding ApbA PF02558.16 KLO14747.1 - 0.0031 17.2 0.1 0.0048 16.5 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KLO14747.1 - 0.0041 17.0 4.6 0.0041 17.0 0.4 2.5 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KLO14747.1 - 0.024 13.9 0.3 0.068 12.5 0.1 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 KLO14747.1 - 0.23 10.8 1.3 0.63 9.4 0.2 2.1 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KLO14748.1 - 7.8e-41 139.7 1.1 1.1e-40 139.2 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO14748.1 - 8.8e-32 110.5 0.9 1.2e-31 110.1 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO14748.1 - 5.2e-12 46.0 0.6 1.8e-11 44.3 0.4 1.8 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 KLO14748.1 - 0.0002 21.3 3.4 0.0059 16.5 0.5 3.1 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KLO14748.1 - 0.0069 16.3 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 KLO14748.1 - 0.014 16.0 0.8 0.022 15.3 0.1 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KLO14748.1 - 0.014 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.19 KLO14748.1 - 0.039 13.3 0.0 0.078 12.3 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KLO14748.1 - 0.09 12.8 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Radical_SAM PF04055.21 KLO14749.1 - 2.3e-17 63.9 0.0 5.8e-17 62.6 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KLO14749.1 - 3.2e-07 30.7 0.1 8.9e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KLO14749.1 - 0.0008 19.5 0.1 0.0028 17.8 0.1 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Peptidase_S28 PF05577.12 KLO14751.1 - 5.1e-54 183.7 0.0 1e-53 182.8 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_3 PF07859.13 KLO14753.1 - 3.5e-18 66.2 0.0 1.3e-13 51.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KLO14753.1 - 6.8e-09 35.5 0.0 6.3e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KLO14753.1 - 4.1e-07 29.3 0.0 4.2e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_6 PF12697.7 KLO14753.1 - 5.8e-07 30.3 0.3 8.5e-07 29.8 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO14753.1 - 4.3e-05 23.3 0.1 0.00043 20.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO14753.1 - 0.0023 17.2 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KLO14753.1 - 0.0039 16.2 0.0 0.0066 15.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase DLH PF01738.18 KLO14753.1 - 0.0041 16.7 0.2 0.014 15.0 0.1 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KLO14753.1 - 0.008 15.1 0.1 0.022 13.7 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Esterase PF00756.20 KLO14753.1 - 0.0089 15.7 0.0 0.14 11.7 0.0 2.3 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KLO14753.1 - 0.056 13.2 0.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase ExoD PF06055.12 KLO14753.1 - 0.08 12.3 0.1 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD Say1_Mug180 PF10340.9 KLO14753.1 - 0.12 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Rad4 PF03835.15 KLO14754.1 - 3.9e-27 94.7 0.1 3.2e-26 91.8 0.0 2.4 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KLO14754.1 - 2e-26 92.2 0.1 4.5e-26 91.1 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KLO14754.1 - 1.4e-19 69.7 0.0 2.9e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KLO14754.1 - 2.4e-16 60.4 0.2 2.4e-16 60.4 0.2 4.0 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KLO14754.1 - 2.2e-06 28.1 0.0 0.0002 21.8 0.0 2.9 3 0 0 3 3 3 1 Transglutaminase-like superfamily GCD14 PF08704.10 KLO14755.1 - 1e-88 297.2 0.0 2.1e-87 292.9 0.0 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KLO14755.1 - 7e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KLO14755.1 - 5.3e-05 23.1 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KLO14755.1 - 0.0014 19.7 1.2 0.0061 17.6 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain Fibrillarin PF01269.17 KLO14755.1 - 0.0022 17.2 0.0 0.0035 16.5 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_4 PF02390.17 KLO14755.1 - 0.007 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltr_RsmB-F PF01189.17 KLO14755.1 - 0.019 14.6 0.1 0.036 13.7 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DUF2052 PF09747.9 KLO14755.1 - 0.019 15.1 2.7 0.03 14.5 2.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Methyltransf_12 PF08242.12 KLO14755.1 - 0.038 14.7 1.1 0.12 13.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KLO14755.1 - 0.04 14.6 0.0 0.079 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TFB6 PF17110.5 KLO14755.1 - 0.089 12.5 3.2 0.06 13.1 1.4 1.6 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF3847 PF12958.7 KLO14755.1 - 0.1 12.8 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) RPN2_C PF18004.1 KLO14755.1 - 2.8 7.9 7.4 4.7 7.1 7.4 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PAS_3 PF08447.12 KLO14756.1 - 0.0047 17.2 0.0 0.015 15.5 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KLO14756.1 - 0.0066 16.6 0.0 0.079 13.1 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.7 KLO14756.1 - 0.05 13.8 0.0 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 PAS domain Pkinase PF00069.25 KLO14757.1 - 1.9e-68 230.7 0.0 3.5e-68 229.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO14757.1 - 2.7e-35 121.9 0.0 1.4e-33 116.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KLO14757.1 - 0.0016 17.8 0.0 0.0097 15.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KLO14757.1 - 0.015 14.1 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KLO14757.1 - 0.027 13.5 0.1 0.048 12.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2235 PF09994.9 KLO14758.1 - 2.6e-87 292.8 0.0 3.2e-87 292.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) CN_hydrolase PF00795.22 KLO14759.1 - 7.3e-17 61.6 0.0 1.5e-16 60.6 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase ATS PF15445.6 KLO14759.1 - 0.094 12.1 0.3 0.13 11.7 0.3 1.1 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 Cullin PF00888.22 KLO14760.1 - 5.2e-20 71.6 0.0 9e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KLO14760.1 - 1.1e-15 57.8 0.0 6.4e-15 55.4 0.0 2.4 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.10 KLO14760.1 - 0.053 13.6 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator ENT PF03735.14 KLO14760.1 - 0.52 10.4 1.9 24 5.1 0.0 3.1 3 0 0 3 3 3 0 ENT domain HSP20 PF00011.21 KLO14761.1 - 7.6e-15 54.9 0.0 2.1e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KLO14761.1 - 4.9e-12 45.2 0.1 2.9e-11 42.7 0.1 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 KLO14761.1 - 0.0037 17.4 2.0 0.026 14.6 0.0 2.1 2 0 0 2 2 2 1 GvpH Ribosomal_60s PF00428.19 KLO14761.1 - 0.017 15.7 2.7 0.018 15.6 1.5 1.6 1 1 1 2 2 2 0 60s Acidic ribosomal protein DUF1325 PF07039.11 KLO14762.1 - 1.6e-34 118.8 0.0 2.7e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 KLO14762.1 - 0.0013 18.5 0.7 0.0048 16.7 0.0 2.3 3 0 0 3 3 3 1 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 KLO14762.1 - 0.094 12.4 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 DUF1918 PF08940.11 KLO14762.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Translin PF01997.16 KLO14763.1 - 3.2e-49 167.7 0.0 3.7e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Translin family TBCC_N PF16752.5 KLO14763.1 - 0.028 14.9 0.0 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain SEN1_N PF12726.7 KLO14764.1 - 5.7e-124 415.0 1.6 9.2e-124 414.3 1.6 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KLO14764.1 - 6.5e-74 249.0 1.8 6.5e-74 249.0 1.8 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KLO14764.1 - 6e-59 199.0 0.0 1.2e-58 198.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KLO14764.1 - 1.2e-09 38.2 0.1 2.1e-05 24.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KLO14764.1 - 2.8e-08 34.2 0.3 1.4e-07 32.0 0.3 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KLO14764.1 - 0.0011 18.8 0.8 1.3 8.7 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase FapA PF03961.13 KLO14764.1 - 0.017 13.8 2.5 0.028 13.0 2.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ResIII PF04851.15 KLO14764.1 - 0.025 14.6 0.1 0.38 10.7 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KLO14764.1 - 0.054 13.0 7.5 0.34 10.4 1.7 2.9 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain CM_2 PF01817.21 KLO14764.1 - 0.095 13.1 0.8 0.51 10.7 0.8 2.3 1 0 0 1 1 1 0 Chorismate mutase type II Snapin_Pallidin PF14712.6 KLO14764.1 - 0.2 12.1 4.3 0.85 10.1 2.7 2.8 3 0 0 3 3 2 0 Snapin/Pallidin AAA_22 PF13401.6 KLO14764.1 - 0.34 11.2 1.4 1.7 8.9 0.1 2.9 3 0 0 3 3 3 0 AAA domain Atg14 PF10186.9 KLO14764.1 - 0.45 9.5 5.6 0.88 8.6 5.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CN_hydrolase PF00795.22 KLO14765.1 - 7.6e-16 58.2 0.0 1.5e-15 57.3 0.0 1.4 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase ATS PF15445.6 KLO14765.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 Pkinase_fungal PF17667.1 KLO14766.1 - 5.7e-22 78.1 0.0 1.1e-15 57.4 0.0 2.3 2 1 0 2 2 2 2 Fungal protein kinase C2 PF00168.30 KLO14768.1 - 1.5e-09 38.1 0.0 2.9e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain CPSF100_C PF13299.6 KLO14768.1 - 1.3 9.1 6.5 0.2 11.9 0.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal AMPKBI PF04739.15 KLO14770.1 - 3e-25 88.3 2.1 2.7e-24 85.2 2.1 2.7 1 1 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KLO14770.1 - 9.8e-19 67.4 0.1 1.8e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase A_deaminase PF00962.22 KLO14771.1 - 3.4e-122 407.9 0.2 4.6e-122 407.4 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF4534 PF15049.6 KLO14774.1 - 3.1 7.5 7.3 0.93 9.2 2.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4534) MFS_1 PF07690.16 KLO14775.1 - 6.6e-10 38.4 7.9 8.3e-10 38.1 7.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO14775.1 - 6.2e-08 31.9 3.5 9.8e-08 31.3 3.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF5518 PF17647.1 KLO14775.1 - 0.011 15.9 6.6 0.016 15.3 6.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5518) MFS_1 PF07690.16 KLO14776.1 - 1.4e-22 80.1 25.5 1.4e-22 80.1 25.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO14776.1 - 4.5e-16 58.8 30.0 2.5e-12 46.4 22.6 1.4 1 1 1 2 2 2 2 Sugar (and other) transporter Aldolase_II PF00596.21 KLO14777.1 - 9.7e-40 136.5 0.0 1.1e-39 136.3 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GXWXG PF14231.6 KLO14777.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 GXWXG protein Peptidase_M15_4 PF13539.6 KLO14777.1 - 0.13 12.8 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase HA2 PF04408.23 KLO14778.1 - 1.6e-25 89.4 0.0 1.6e-25 89.4 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KLO14778.1 - 1.9e-15 57.0 0.0 6.3e-15 55.3 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KLO14778.1 - 3.9e-12 46.5 0.6 2.1e-10 40.9 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO14778.1 - 3.5e-08 33.4 0.2 1.1e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KLO14778.1 - 4.6e-06 27.0 0.0 2.3e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KLO14778.1 - 0.00095 19.5 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KLO14778.1 - 0.0011 18.3 0.0 0.0025 17.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KLO14778.1 - 0.0058 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KLO14778.1 - 0.029 14.4 0.0 0.029 14.4 0.0 3.0 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit ATPase PF06745.13 KLO14778.1 - 0.037 13.4 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 KLO14778.1 - 0.04 13.0 0.0 0.095 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KLO14778.1 - 0.095 13.2 0.0 0.095 13.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF4692 PF15763.5 KLO14778.1 - 0.11 13.0 1.0 0.32 11.4 1.0 1.7 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) CobS PF02654.15 KLO14781.1 - 0.0053 17.0 2.2 0.011 16.0 2.2 1.5 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase UQ_con PF00179.26 KLO14782.1 - 1.3e-10 41.0 0.0 2.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme tRNA_int_end_N2 PF12928.7 KLO14783.1 - 2.5e-17 62.8 0.0 4.1e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KLO14783.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain F-box-like PF12937.7 KLO14784.1 - 4.6e-11 42.4 0.3 4.6e-11 42.4 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO14784.1 - 0.00013 21.8 0.1 0.00045 20.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain 4HBT_3 PF13622.6 KLO14787.1 - 3e-16 60.4 0.1 1.1e-15 58.6 0.1 1.8 1 1 0 1 1 1 1 Thioesterase-like superfamily Asp PF00026.23 KLO14788.1 - 8.9e-48 163.3 12.0 3.1e-47 161.5 12.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO14788.1 - 1.4e-07 31.9 6.8 0.00014 22.1 0.2 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal ABC2_membrane PF01061.24 KLO14790.1 - 1e-32 113.3 19.1 1e-32 113.3 19.1 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KLO14790.1 - 1.7e-21 77.2 0.1 2.6e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KLO14790.1 - 3.7e-07 30.3 0.0 0.0043 16.9 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KLO14790.1 - 0.00082 19.3 0.2 0.01 15.8 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KLO14790.1 - 0.0009 18.5 19.3 0.0018 17.4 19.3 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 KLO14790.1 - 0.0058 16.3 0.1 0.026 14.3 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 KLO14790.1 - 0.008 16.1 0.0 0.017 15.1 0.0 1.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 KLO14790.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KLO14790.1 - 0.015 15.7 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 KLO14790.1 - 0.025 14.0 0.1 1.1 8.7 0.1 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KLO14790.1 - 0.028 15.0 0.0 0.057 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KLO14790.1 - 0.035 14.5 0.1 0.52 10.7 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KLO14790.1 - 0.057 13.1 0.1 0.086 12.6 0.1 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_33 PF13671.6 KLO14790.1 - 0.087 13.0 0.0 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KLO14790.1 - 0.17 12.1 0.0 0.54 10.5 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Fungal_trans PF04082.18 KLO14791.1 - 7.8e-15 54.6 0.0 3.1e-14 52.7 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO14791.1 - 5e-05 23.3 8.2 8.6e-05 22.6 8.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase_fungal PF17667.1 KLO14792.1 - 2e-46 158.6 0.0 1.2e-45 156.0 0.0 1.9 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO14792.1 - 0.00028 20.4 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO14792.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KLO14792.1 - 0.089 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Glyco_hydro_10 PF00331.20 KLO14793.1 - 1.3e-95 320.2 0.0 1.6e-95 319.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_transf_28 PF03033.20 KLO14794.1 - 7.9e-25 87.5 0.0 2e-24 86.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KLO14794.1 - 1.4e-09 37.3 0.0 4.1e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_BEACH PF14844.6 KLO14794.1 - 0.0029 17.7 0.0 0.015 15.4 0.0 2.2 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH PH PF00169.29 KLO14794.1 - 0.045 14.3 0.0 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 PH domain Dynein_light PF01221.18 KLO14795.1 - 2.5e-25 88.6 1.1 3.3e-25 88.2 1.1 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 3HCDH_N PF02737.18 KLO14796.1 - 1.1e-47 162.2 0.5 1.8e-45 155.0 0.5 2.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KLO14796.1 - 7.5e-17 61.7 0.3 1.1e-13 51.6 0.3 3.9 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain AlaDh_PNT_C PF01262.21 KLO14796.1 - 0.00058 19.2 0.1 0.0013 18.1 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KLO14796.1 - 0.0027 17.0 0.1 0.0047 16.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KLO14796.1 - 0.0049 17.1 0.1 0.044 14.0 0.0 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 KLO14796.1 - 0.0081 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KLO14796.1 - 0.01 16.4 0.1 0.022 15.3 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KLO14796.1 - 0.02 15.4 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Methyltransf_25 PF13649.6 KLO14796.1 - 0.03 15.0 0.1 1.7 9.4 0.0 2.7 3 0 0 3 3 2 0 Methyltransferase domain LPD7 PF18821.1 KLO14796.1 - 0.068 13.3 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 2-Hacid_dh_C PF02826.19 KLO14796.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.15 KLO14796.1 - 0.47 10.3 8.8 0.37 10.6 0.5 3.2 1 1 2 3 3 3 0 DNA / pantothenate metabolism flavoprotein NAD_binding_8 PF13450.6 KLO14796.1 - 2.7 8.3 5.0 0.33 11.2 0.4 1.9 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Aldo_ket_red PF00248.21 KLO14798.1 - 1e-37 129.9 0.7 2.8e-18 66.1 0.0 3.0 2 1 1 3 3 3 3 Aldo/keto reductase family Pkinase_fungal PF17667.1 KLO14800.1 - 5.9e-10 38.5 0.0 7.9e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF2675 PF11247.8 KLO14800.1 - 0.1 12.7 0.0 1.9 8.7 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2675) WD40 PF00400.32 KLO14801.1 - 2.4e-27 94.6 0.1 8.6e-06 26.4 0.1 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO14801.1 - 3e-09 37.0 0.0 0.0051 17.1 0.1 5.2 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KLO14801.1 - 9.7e-05 21.2 1.1 0.0021 16.8 0.3 2.6 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KLO14801.1 - 0.00028 19.5 0.0 0.00046 18.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 KLO14801.1 - 0.00031 19.9 0.1 0.35 9.9 0.0 2.4 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 KLO14801.1 - 0.00055 19.9 0.7 0.75 9.6 0.0 3.1 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KLO14801.1 - 0.0046 15.8 0.4 1.1 8.0 0.1 2.7 2 1 1 3 3 3 2 Nup133 N terminal like WD40_like PF17005.5 KLO14801.1 - 0.02 14.2 0.0 0.39 10.0 0.0 2.8 3 1 1 5 5 5 0 WD40-like domain PQQ_2 PF13360.6 KLO14801.1 - 0.034 13.7 0.4 0.078 12.5 0.4 1.8 1 1 0 1 1 1 0 PQQ-like domain Ribosomal_S19e PF01090.19 KLO14802.1 - 3.3e-58 195.3 0.1 3.8e-58 195.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribonuc_red_lgC PF02867.15 KLO14804.1 - 2.3e-181 603.9 0.0 2.9e-181 603.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KLO14804.1 - 1.3e-24 86.0 0.1 2.9e-24 84.9 0.1 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KLO14804.1 - 6.5e-15 55.5 0.0 1.6e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain Cullin PF00888.22 KLO14805.1 - 6.2e-187 623.0 8.1 9.9e-187 622.3 8.1 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KLO14805.1 - 2.6e-27 94.7 2.6 2.6e-27 94.7 2.6 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 KLO14805.1 - 0.58 10.5 9.3 4.9 7.6 0.2 3.8 4 0 0 4 4 4 0 Penicillinase repressor Ribosomal_L28 PF00830.19 KLO14805.1 - 0.78 10.0 4.4 3.5 7.9 0.0 3.5 4 0 0 4 4 4 0 Ribosomal L28 family PSK_trans_fac PF07704.11 KLO14806.1 - 0.38 11.5 1.5 1.1 10.1 1.5 1.7 1 0 0 1 1 1 0 Rv0623-like transcription factor DUF2478 PF10649.9 KLO14807.1 - 0.051 13.2 0.1 0.055 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) HAT_KAT11 PF08214.11 KLO14808.1 - 3.9e-39 134.9 0.0 5.6e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein zf-MYND PF01753.18 KLO14809.1 - 3.3e-07 30.3 15.2 3.3e-07 30.3 15.2 2.6 2 0 0 2 2 2 1 MYND finger Rhodopsin_N PF10413.9 KLO14809.1 - 0.057 13.2 0.3 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin KH_9 PF17904.1 KLO14809.1 - 0.11 12.9 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 FMRP KH0 domain MRP-L20 PF12824.7 KLO14810.1 - 1.4e-24 87.1 4.3 1.7e-24 86.8 4.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 SDA1 PF05285.12 KLO14810.1 - 0.0045 16.5 0.0 0.0045 16.5 0.0 1.1 1 0 0 1 1 1 1 SDA1 Metal_resist PF13801.6 KLO14810.1 - 0.21 11.8 2.4 0.58 10.3 1.0 2.1 2 0 0 2 2 2 0 Heavy-metal resistance ICL PF00463.21 KLO14811.1 - 5.7e-253 840.2 0.0 6.5e-253 840.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KLO14811.1 - 1.7e-08 34.2 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase NuA4 PF09340.10 KLO14812.1 - 8.8e-23 80.0 1.4 8.8e-23 80.0 1.4 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 SET PF00856.28 KLO14813.1 - 5.9e-10 39.8 0.1 6.6e-08 33.1 0.1 3.0 2 1 0 2 2 2 1 SET domain dCMP_cyt_deam_1 PF00383.23 KLO14813.1 - 5.9e-07 29.3 0.0 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KLO14813.1 - 0.00025 20.8 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase HET PF06985.11 KLO14814.1 - 4.6e-08 33.5 6.6 0.00084 19.7 0.1 3.4 3 0 0 3 3 3 3 Heterokaryon incompatibility protein (HET) tRNA-Thr_ED PF08915.11 KLO14814.1 - 0.17 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase Glycos_transf_4 PF00953.21 KLO14815.1 - 1e-30 106.9 9.6 1e-30 106.9 9.6 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 Osw5 PF17062.5 KLO14815.1 - 0.15 12.1 5.0 0.14 12.3 1.6 2.8 2 0 0 2 2 2 0 Outer spore wall 5 DUF3421 PF11901.8 KLO14816.1 - 8.5e-24 83.8 0.1 2.4e-18 66.2 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) HET PF06985.11 KLO14817.1 - 8.8e-07 29.4 2.7 0.026 14.9 0.1 4.3 4 0 0 4 4 4 3 Heterokaryon incompatibility protein (HET) HET PF06985.11 KLO14820.1 - 0.00058 20.2 0.8 0.0032 17.8 0.1 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 KLO14821.1 - 1.2e-05 25.1 0.0 3e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KLO14821.1 - 0.2 11.8 0.2 6.7 7.0 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat Ubie_methyltran PF01209.18 KLO14822.1 - 1.7e-80 269.7 0.0 2.2e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KLO14822.1 - 9.5e-16 58.3 0.0 1.9e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO14822.1 - 1.8e-12 47.7 0.0 3.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO14822.1 - 2.1e-11 44.5 0.0 3.4e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO14822.1 - 9.5e-11 41.8 0.0 1.5e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO14822.1 - 2.3e-09 37.2 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KLO14822.1 - 0.074 13.0 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase His_Me_b4a2 PF18275.1 KLO14822.1 - 0.14 12.2 0.8 0.32 11.1 0.8 1.6 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain FrhB_FdhB_C PF04432.13 KLO14822.1 - 0.16 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Glyco_transf_90 PF05686.12 KLO14822.1 - 0.19 10.6 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 90 Fcf2 PF08698.11 KLO14823.1 - 1.4e-26 92.7 0.0 4.8e-26 91.0 0.0 1.8 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing Chorion_2 PF03964.15 KLO14823.1 - 0.014 16.2 0.8 0.097 13.5 0.3 2.2 2 1 0 2 2 2 0 Chorion family 2 NAD_binding_10 PF13460.6 KLO14824.1 - 1.4e-13 51.1 0.0 2.4e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KLO14824.1 - 1.4e-11 44.3 0.1 1.3e-10 41.2 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KLO14824.1 - 4.3e-11 42.8 0.0 7.9e-11 42.0 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 KLO14824.1 - 4.8e-10 39.0 0.0 3.2e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KLO14824.1 - 6.2e-10 38.5 0.0 1.6e-08 33.9 0.0 2.1 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KLO14824.1 - 2.2e-05 23.7 0.1 0.036 13.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KLO14824.1 - 2.4e-05 23.9 0.1 3.8e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KLO14824.1 - 0.0033 16.9 0.1 0.019 14.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KLO14824.1 - 0.013 14.6 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 KLO14824.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF2462 PF09495.10 KLO14825.1 - 5.2e-19 68.7 12.8 6.8e-19 68.4 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) HRI1 PF16815.5 KLO14826.1 - 1.5e-51 175.4 0.6 1.8e-51 175.0 0.6 1.1 1 0 0 1 1 1 1 Protein HRI1 Wzy_C_2 PF11846.8 KLO14826.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal CpeS PF09367.10 KLO14826.1 - 0.12 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 CpeS-like protein Glyco_hydro_35 PF01301.19 KLO14827.1 - 2.5e-79 267.2 0.1 3.6e-79 266.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KLO14827.1 - 6.3e-58 194.3 5.9 7.7e-33 113.5 0.1 3.4 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KLO14827.1 - 1.3e-38 132.6 4.2 2.4e-38 131.8 4.2 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KLO14827.1 - 8.9e-22 76.5 0.1 2.4e-21 75.1 0.1 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Fic PF02661.18 KLO14829.1 - 6.6e-08 33.4 0.0 1.1e-07 32.7 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family Sas10 PF09368.10 KLO14830.1 - 2.5e-24 85.6 3.8 2.5e-24 85.6 3.8 3.8 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KLO14830.1 - 1.9e-05 25.2 0.4 1.9e-05 25.2 0.4 3.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family EPL1 PF10513.9 KLO14831.1 - 6.3e-20 72.1 1.3 1.9e-19 70.6 0.0 2.4 3 0 0 3 3 3 1 Enhancer of polycomb-like TPP_enzyme_N PF02776.18 KLO14832.1 - 5.5e-34 117.2 0.0 9.2e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KLO14832.1 - 7.7e-16 58.1 0.0 1.6e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KLO14832.1 - 9e-13 48.3 0.0 4.9e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF362 PF04015.12 KLO14832.1 - 0.056 13.7 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Pap_E4 PF02711.14 KLO14833.1 - 0.011 16.7 0.1 0.021 15.8 0.1 1.4 1 0 0 1 1 1 0 E4 protein RNA_pol_3_Rpc31 PF11705.8 KLO14834.1 - 0.0027 18.0 4.9 0.0034 17.7 4.9 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.11 KLO14834.1 - 0.0044 17.1 2.8 0.0065 16.5 2.8 1.2 1 0 0 1 1 1 1 RXT2-like, N-terminal DNA_pol_phi PF04931.13 KLO14834.1 - 0.0071 14.5 6.9 0.0085 14.3 6.9 1.2 1 0 0 1 1 1 1 DNA polymerase phi Sigma70_ner PF04546.13 KLO14834.1 - 0.014 15.3 4.3 0.018 14.9 4.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Tim54 PF11711.8 KLO14834.1 - 0.025 13.4 0.3 0.029 13.2 0.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CENP-B_dimeris PF09026.10 KLO14834.1 - 0.075 13.4 14.5 0.12 12.8 14.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 KLO14834.1 - 0.075 12.7 9.4 0.1 12.3 9.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 KLO14834.1 - 0.092 12.4 2.6 0.13 11.9 2.6 1.3 1 0 0 1 1 1 0 FAM176 family KH_dom-like PF14714.6 KLO14834.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal DUF2457 PF10446.9 KLO14834.1 - 0.22 10.6 10.4 0.29 10.2 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.16 KLO14834.1 - 0.23 10.6 1.4 0.28 10.3 1.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 KLO14834.1 - 0.33 9.1 7.6 0.41 8.8 7.6 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KLO14834.1 - 0.58 8.4 5.9 0.71 8.1 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KLO14834.1 - 0.89 8.9 8.2 1.2 8.5 8.2 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 KLO14834.1 - 3.6 6.8 14.2 5 6.4 14.2 1.1 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.13 KLO14834.1 - 3.6 7.5 8.2 4.2 7.2 8.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PI3K_1B_p101 PF10486.9 KLO14835.1 - 0.075 10.8 0.8 0.09 10.6 0.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PBP1_TM PF14812.6 KLO14835.1 - 0.077 13.4 5.9 0.13 12.7 5.9 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KLO14835.1 - 1.2 8.8 3.6 1.6 8.4 3.6 1.1 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 KLO14836.1 - 0.75 10.2 3.8 1.4 9.4 3.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 KLO14836.1 - 2 6.4 3.9 2.6 6.0 3.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi TraW_N PF12477.8 KLO14839.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal Rho_N PF07498.12 KLO14841.1 - 0.037 14.0 0.1 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain DUF5024 PF16427.5 KLO14841.1 - 0.051 13.9 0.1 0.087 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5024) BBIP10 PF14777.6 KLO14841.1 - 0.054 13.1 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 MOZ_SAS PF01853.18 KLO14843.1 - 7.3e-80 266.9 0.2 1.1e-79 266.3 0.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KLO14843.1 - 1e-21 76.3 1.9 2.1e-21 75.3 1.9 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KLO14843.1 - 1.4e-15 56.9 0.1 3e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HTH_Mga PF08280.11 KLO14843.1 - 9e-05 22.4 0.3 0.0002 21.3 0.3 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Acetyltransf_7 PF13508.7 KLO14843.1 - 0.0073 16.7 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_11 PF08279.12 KLO14843.1 - 0.024 14.6 0.1 0.058 13.3 0.1 1.6 1 0 0 1 1 1 0 HTH domain Acetyltransf_1 PF00583.25 KLO14843.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Pox_Ag35 PF03286.14 KLO14843.1 - 5.2 6.8 9.3 16 5.2 9.3 1.7 1 1 0 1 1 1 0 Pox virus Ag35 surface protein DDE_1 PF03184.19 KLO14845.1 - 8.7e-18 64.6 0.0 1.4e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO14845.1 - 0.0073 16.1 0.0 0.17 11.6 0.0 2.7 3 1 0 3 3 3 1 DDE superfamily endonuclease FA_desaturase PF00487.24 KLO14847.1 - 1.9e-20 73.8 25.6 1.9e-20 73.8 25.6 2.0 2 1 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 KLO14847.1 - 0.022 14.9 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) NAD_binding_10 PF13460.6 KLO14848.1 - 0.00028 20.8 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding D123 PF07065.14 KLO14849.1 - 2.9e-86 289.4 0.0 4.2e-86 288.9 0.0 1.2 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 KLO14849.1 - 0.07 13.1 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 KLO14849.1 - 0.16 11.8 0.0 0.63 9.9 0.0 2.0 3 0 0 3 3 3 0 ATP-grasp domain, R2K clade family 2 Alliinase_C PF04864.13 KLO14852.1 - 0.083 11.8 0.2 0.11 11.4 0.2 1.1 1 0 0 1 1 1 0 Allinase DDE_1 PF03184.19 KLO14856.1 - 1.5e-19 70.3 0.0 2.3e-19 69.7 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease Radical_SAM_C PF16199.5 KLO14856.1 - 0.12 12.4 0.0 6 7.0 0.0 2.4 2 0 0 2 2 2 0 Radical_SAM C-terminal domain DS PF01916.17 KLO14856.1 - 0.14 11.4 0.0 15 4.7 0.0 2.2 2 0 0 2 2 2 0 Deoxyhypusine synthase DEAD PF00270.29 KLO14857.1 - 0.00058 19.7 0.0 0.00065 19.5 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase FAM176 PF14851.6 KLO14858.1 - 0.012 15.2 0.5 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 FAM176 family TPR_21 PF09976.9 KLO14858.1 - 0.02 14.6 0.1 0.031 14.0 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TMEM100 PF16311.5 KLO14858.1 - 0.037 13.6 0.9 0.058 13.0 0.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 100 DUF2852 PF11014.8 KLO14858.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Phage_holin_3_3 PF16083.5 KLO14858.1 - 0.35 11.0 5.5 2.5 8.3 0.1 2.7 2 1 0 2 2 2 0 LydA holin phage, holin superfamily III Fungal_trans PF04082.18 KLO14859.1 - 8e-11 41.5 0.1 1.3e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO14859.1 - 1.2e-06 28.5 11.8 2.2e-06 27.7 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KLO14860.1 - 0.0063 17.3 2.4 0.054 14.4 0.1 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat ING PF12998.7 KLO14861.1 - 3.3e-12 46.9 0.0 8.8e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KLO14861.1 - 8.6e-06 25.5 8.2 1.4e-05 24.9 8.2 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KLO14861.1 - 0.67 10.2 5.2 2 8.7 4.7 1.9 1 1 1 2 2 2 0 PHD-like zinc-binding domain GalP_UDP_transf PF01087.22 KLO14862.1 - 6.4e-61 206.0 0.0 9.5e-61 205.4 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KLO14862.1 - 9.5e-47 158.8 0.0 1.7e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KLO14862.1 - 0.00068 20.3 0.0 0.0025 18.5 0.0 2.0 2 1 0 2 2 2 1 HIT domain DUF4921 PF16268.5 KLO14862.1 - 0.021 13.7 0.0 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) DcpS_C PF11969.8 KLO14862.1 - 0.029 14.9 0.0 0.059 13.8 0.0 1.6 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Sel1 PF08238.12 KLO14863.1 - 2.4e-54 180.6 16.5 1.6e-09 38.1 0.0 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_14 PF13428.6 KLO14863.1 - 0.42 11.6 9.5 5.3 8.1 0.4 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat RNA12 PF10443.9 KLO14864.1 - 5.7e-120 401.0 0.4 4.3e-64 216.9 0.1 2.2 1 1 1 2 2 2 2 RNA12 protein AAA_16 PF13191.6 KLO14864.1 - 6.4e-05 23.4 0.0 0.0003 21.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KLO14864.1 - 0.00026 21.0 0.0 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA PF00004.29 KLO14864.1 - 0.00032 21.1 0.0 0.00068 20.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO14864.1 - 0.0021 18.3 0.1 0.011 16.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain RraB PF06877.11 KLO14864.1 - 0.02 15.6 0.0 0.22 12.2 0.0 2.5 2 0 0 2 2 2 0 Regulator of ribonuclease activity B AAA_33 PF13671.6 KLO14864.1 - 0.043 14.0 0.5 0.17 12.0 0.2 2.3 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 KLO14864.1 - 0.067 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FAD-oxidase_C PF02913.19 KLO14864.1 - 0.068 12.8 0.5 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain RNA_helicase PF00910.22 KLO14864.1 - 0.094 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KLO14864.1 - 0.14 12.2 0.0 0.53 10.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KLO14864.1 - 0.95 9.9 0.0 0.95 9.9 0.0 2.7 3 1 0 3 3 3 0 AAA domain F-box-like PF12937.7 KLO14866.1 - 1.7e-08 34.2 0.4 4.3e-08 32.9 0.4 1.7 1 0 0 1 1 1 1 F-box-like DUF3984 PF13136.6 KLO14866.1 - 0.067 12.6 1.5 0.16 11.3 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) HMA PF00403.26 KLO14867.1 - 2.6e-11 43.8 0.8 4.6e-11 43.0 0.8 1.4 1 1 0 1 1 1 1 Heavy-metal-associated domain Pro_Al_protease PF02983.14 KLO14867.1 - 0.096 12.8 0.4 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 Alpha-lytic protease prodomain DUF3320 PF11784.8 KLO14867.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) COX16 PF14138.6 KLO14868.1 - 6.6e-31 106.7 0.2 7.7e-31 106.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 YjcZ_2 PF09680.10 KLO14868.1 - 0.083 12.5 0.3 0.12 12.0 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function ATP-synt_J PF04911.12 KLO14869.1 - 1e-18 66.6 0.1 1.3e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 ATP synthase j chain DUF4203 PF13886.6 KLO14870.1 - 1e-14 54.7 24.1 1.4e-14 54.3 24.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) MMR_HSR1 PF01926.23 KLO14871.1 - 9.6e-08 32.1 0.0 5.7e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KLO14871.1 - 4.6e-07 29.4 0.0 1.7e-06 27.6 0.1 1.8 2 0 0 2 2 2 1 AIG1 family MACPF PF01823.19 KLO14871.1 - 1.3e-05 25.4 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 MAC/Perforin domain RsgA_GTPase PF03193.16 KLO14871.1 - 0.00039 20.4 0.3 0.00073 19.5 0.3 1.4 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 KLO14871.1 - 0.0044 16.3 0.1 0.0073 15.6 0.1 1.3 1 0 0 1 1 1 1 Septin ApoO PF09769.9 KLO14871.1 - 0.0097 15.9 0.2 1 9.3 0.0 3.0 3 0 0 3 3 3 1 Apolipoprotein O ABC_tran PF00005.27 KLO14871.1 - 0.014 16.0 0.0 0.034 14.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 KLO14871.1 - 0.04 13.5 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 KLO14871.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KLO14871.1 - 0.17 12.1 0.0 0.72 10.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain Het-C PF07217.11 KLO14872.1 - 1.9e-189 630.9 0.0 3.4e-111 372.5 0.0 2.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein Het-C DUF2746 PF10874.8 KLO14872.1 - 0.039 14.4 0.2 0.15 12.5 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Prenyltransf PF01255.19 KLO14873.1 - 3.5e-76 255.6 0.0 4.4e-76 255.3 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase HSF_DNA-bind PF00447.17 KLO14874.1 - 3.7e-31 107.6 6.3 3.7e-31 107.6 6.3 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 KLO14874.1 - 1e-25 90.0 0.3 2.7e-25 88.7 0.3 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Dyp_perox PF04261.12 KLO14875.1 - 7.9e-05 21.8 0.0 0.05 12.6 0.0 2.6 2 1 0 2 2 2 2 Dyp-type peroxidase family RicinB_lectin_2 PF14200.6 KLO14875.1 - 0.0046 17.7 2.6 0.021 15.5 1.8 2.3 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like GMC_oxred_C PF05199.13 KLO14876.1 - 3.8e-17 63.1 0.0 7.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KLO14876.1 - 2.1e-06 27.3 0.0 1.2e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase RicinB_lectin_2 PF14200.6 KLO14876.1 - 0.0023 18.6 2.7 0.024 15.3 1.0 2.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like VWA PF00092.28 KLO14877.1 - 1.3e-10 41.8 0.0 2.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KLO14877.1 - 8.4e-09 36.0 0.0 1.5e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain TssR PF17643.1 KLO14877.1 - 0.043 11.8 0.0 0.062 11.3 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR CNH PF00780.22 KLO14878.1 - 0.02 14.5 0.0 0.18 11.4 0.0 2.1 1 1 1 2 2 2 0 CNH domain HALZ PF02183.18 KLO14878.1 - 0.11 12.8 0.4 0.19 12.0 0.4 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper NAD_binding_10 PF13460.6 KLO14879.1 - 5.1e-24 85.2 0.0 6e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KLO14879.1 - 1.6e-09 37.6 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KLO14879.1 - 2e-06 27.5 0.0 3.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KLO14879.1 - 5.2e-05 22.8 0.0 8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KLO14879.1 - 0.00028 20.0 0.0 0.00041 19.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KLO14879.1 - 0.00071 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KLO14879.1 - 0.0031 17.0 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KLO14879.1 - 0.0035 17.6 0.0 0.0059 16.9 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KLO14879.1 - 0.09 13.4 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KLO14879.1 - 0.13 11.6 0.1 12 5.3 0.0 2.6 2 2 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F-box-like PF12937.7 KLO14880.1 - 3.4e-08 33.3 1.2 1.6e-07 31.1 1.2 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO14880.1 - 0.26 11.2 2.7 17 5.4 0.5 3.5 3 0 0 3 3 3 0 F-box domain PBP PF01161.20 KLO14881.1 - 1.1e-12 48.4 0.0 1.7e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein F-box-like PF12937.7 KLO14882.1 - 4e-07 29.8 4.6 1.2e-06 28.3 4.6 1.9 1 1 0 1 1 1 1 F-box-like Pkinase_Tyr PF07714.17 KLO14883.1 - 1.3e-44 152.4 0.0 1.2e-43 149.3 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 KLO14883.1 - 6e-36 124.1 0.0 9.4e-35 120.2 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain RasGEF PF00617.19 KLO14883.1 - 1.8e-28 99.9 0.1 6.5e-28 98.1 0.1 2.0 2 0 0 2 2 2 1 RasGEF domain Kinase-like PF14531.6 KLO14883.1 - 0.00033 20.1 0.0 0.00076 18.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO14883.1 - 0.015 14.7 0.0 0.095 12.0 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RasGEF PF00617.19 KLO14885.1 - 3.7e-26 92.4 0.0 8e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain Per1 PF04080.13 KLO14887.1 - 1e-99 333.5 3.8 1.2e-99 333.2 3.8 1.0 1 0 0 1 1 1 1 Per1-like family DUF1635 PF07795.11 KLO14888.1 - 6.7e-05 22.9 0.0 0.36 10.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1635) SR-25 PF10500.9 KLO14888.1 - 0.0019 17.9 8.3 0.89 9.1 0.0 3.2 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein CAP_N PF01213.19 KLO14888.1 - 8.5 5.8 16.8 0.73 9.3 3.0 3.2 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Adenylsucc_synt PF00709.21 KLO14889.1 - 3.7e-172 573.0 0.0 4.2e-172 572.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Clathrin PF00637.20 KLO14890.1 - 3.5e-17 62.6 1.9 1.2e-12 47.9 0.7 3.5 3 1 0 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.8 KLO14890.1 - 5.4e-12 45.7 0.3 1.1e-11 44.8 0.3 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KLO14890.1 - 1.5e-08 34.5 8.2 1.5e-08 34.5 8.2 1.9 2 0 0 2 2 2 1 Zinc-finger zf-C3HC4_2 PF13923.6 KLO14890.1 - 0.00074 19.3 7.5 0.0013 18.5 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO14890.1 - 0.011 16.1 7.7 0.023 15.1 7.7 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KLO14890.1 - 0.14 12.2 7.4 0.23 11.4 7.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KLO14890.1 - 0.72 9.9 5.9 1.5 8.9 5.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 KLO14890.1 - 1.5 9.1 7.2 3 8.2 7.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain But2 PF09792.9 KLO14891.1 - 1.3e-09 38.6 0.0 2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain zf-RING_2 PF13639.6 KLO14892.1 - 5.6e-05 23.4 10.6 5.6e-05 23.4 10.6 2.0 2 0 0 2 2 2 1 Ring finger domain C1_1 PF00130.22 KLO14892.1 - 0.0058 16.5 7.7 0.0058 16.5 7.7 2.6 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 KLO14892.1 - 0.042 13.8 7.9 0.084 12.8 7.9 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Baseplate_J PF04865.14 KLO14892.1 - 0.066 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Baseplate J-like protein PHD PF00628.29 KLO14892.1 - 0.23 11.4 12.1 0.44 10.5 12.1 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KLO14892.1 - 0.26 11.5 9.9 0.41 10.8 8.5 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KLO14892.1 - 0.4 10.6 7.5 1.2 9.1 7.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KLO14892.1 - 0.47 10.4 12.1 0.97 9.4 10.6 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.6 KLO14892.1 - 0.5 10.4 6.8 1.4 9.0 6.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger PHD_2 PF13831.6 KLO14892.1 - 1.5 8.5 8.1 2.9 7.5 8.1 1.5 1 0 0 1 1 1 0 PHD-finger SR-25 PF10500.9 KLO14892.1 - 1.9 8.0 11.1 0.48 10.0 5.2 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Zn_ribbon_17 PF17120.5 KLO14892.1 - 5.6 6.7 13.6 0.91 9.2 9.1 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Terpene_synth_C PF03936.16 KLO14895.1 - 1.8e-05 24.2 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.6 KLO14895.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal RCDG1 PF15725.5 KLO14895.1 - 0.15 12.5 0.7 0.36 11.3 0.7 1.6 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein DUF3429 PF11911.8 KLO14896.1 - 4.1e-41 140.6 15.6 5.3e-41 140.3 15.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Tetraspanin PF00335.20 KLO14897.1 - 0.049 13.3 18.6 0.11 12.2 18.6 1.7 1 1 0 1 1 1 0 Tetraspanin family ResB PF05140.14 KLO14897.1 - 0.096 11.4 0.9 0.79 8.4 0.1 2.0 2 0 0 2 2 2 0 ResB-like family YscJ_FliF PF01514.17 KLO14897.1 - 0.21 11.2 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family DUF4191 PF13829.6 KLO14897.1 - 0.71 9.2 9.3 2.9 7.2 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) Baculo_11_kDa PF06143.11 KLO14897.1 - 7.7 6.2 7.3 18 5.0 0.0 3.0 3 1 0 3 3 3 0 Baculovirus 11 kDa family Bmt2 PF11968.8 KLO14898.1 - 7.3e-60 202.6 0.0 9.5e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 DUF3459 PF11941.8 KLO14898.1 - 0.012 15.9 0.2 0.025 14.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) IQCJ-SCHIP1 PF15157.6 KLO14898.1 - 0.13 12.1 0.8 0.33 10.8 1.0 1.5 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif FAD-oxidase_C PF02913.19 KLO14899.1 - 2.4e-58 197.7 0.1 4.6e-58 196.8 0.1 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KLO14899.1 - 6.4e-33 113.4 0.1 1.2e-32 112.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DUF3736 PF12540.8 KLO14899.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) 5_nucleotid_C PF02872.18 KLO14900.1 - 9e-28 97.5 0.0 1.9e-27 96.4 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KLO14900.1 - 1.3e-09 38.8 0.4 2e-09 38.2 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MBF1 PF08523.10 KLO14901.1 - 5.6e-09 36.3 0.2 5.7e-07 29.9 0.4 2.2 1 1 1 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KLO14901.1 - 8.5e-08 32.2 0.1 1.4e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KLO14901.1 - 5.3e-05 23.5 0.0 0.00015 22.1 0.0 1.6 1 1 1 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KLO14901.1 - 0.0013 18.2 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_25 PF13413.6 KLO14901.1 - 0.0055 16.5 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KLO14901.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KLO14901.1 - 0.011 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.6 KLO14901.1 - 0.028 14.2 0.1 0.065 13.0 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 KLO14901.1 - 0.043 13.4 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KLO14901.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain MBF1 PF08523.10 KLO14902.1 - 4.9e-26 91.0 3.0 9.6e-26 90.0 3.0 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KLO14902.1 - 3.2e-13 49.5 0.3 5.4e-13 48.8 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KLO14902.1 - 1.5e-07 31.6 0.0 3.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KLO14902.1 - 4.3e-05 23.5 0.1 6.8e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KLO14902.1 - 0.031 14.1 0.1 0.051 13.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.6 KLO14902.1 - 0.086 12.8 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Tubulin PF00091.25 KLO14903.1 - 9.5e-71 238.1 0.0 2.2e-70 236.9 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KLO14903.1 - 6.9e-45 152.3 0.3 1.5e-44 151.2 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KLO14903.1 - 5.5e-05 23.5 0.0 0.00016 21.9 0.0 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KLO14903.1 - 0.0034 17.1 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KLO14903.1 - 0.061 12.5 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Tubulin like DEAD PF00270.29 KLO14904.1 - 3.8e-52 176.6 0.0 1.7e-51 174.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO14904.1 - 4.5e-14 52.7 0.0 1.5e-12 47.8 0.0 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO14904.1 - 8e-07 29.2 0.0 3.1e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RGS-like PF09128.11 KLO14904.1 - 0.016 14.9 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Helicase_C PF00271.31 KLO14905.1 - 2.7e-05 24.5 0.1 2.7e-05 24.5 0.1 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FAD_binding_3 PF01494.19 KLO14906.1 - 1.5e-14 54.0 4.0 1.2e-10 41.2 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 KLO14906.1 - 0.0053 15.9 0.0 0.036 13.1 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KLO14906.1 - 0.017 14.3 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO14906.1 - 0.018 15.3 0.1 0.055 13.7 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4112 PF13430.6 KLO14907.1 - 9.8e-22 77.2 0.0 1.3e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2070 PF09843.9 KLO14908.1 - 0.39 8.9 4.5 0.54 8.5 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) WD40 PF00400.32 KLO14909.1 - 8.6e-27 92.9 19.6 9.1e-05 23.2 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KLO14909.1 - 7e-13 48.2 4.7 1.7e-12 47.1 4.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO14909.1 - 2.1e-06 27.5 2.5 5.4e-06 26.1 2.5 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KLO14909.1 - 8.1e-05 21.5 0.1 0.59 8.7 0.0 3.6 4 0 0 4 4 4 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KLO14909.1 - 0.003 18.0 0.1 1.5 9.4 0.0 3.6 3 0 0 3 3 3 1 PQQ-like domain ANAPC4_WD40 PF12894.7 KLO14909.1 - 0.0043 17.3 0.1 18 5.7 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KLO14909.1 - 0.011 15.3 0.1 0.22 11.1 0.1 2.4 2 1 1 3 3 3 0 PQQ-like domain MgtE_N PF03448.17 KLO14909.1 - 0.038 14.6 0.2 0.072 13.7 0.2 1.3 1 0 0 1 1 1 0 MgtE intracellular N domain SH3_9 PF14604.6 KLO14910.1 - 3.9e-10 39.4 0.0 7.1e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KLO14910.1 - 4.9e-06 26.1 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KLO14910.1 - 5.7e-06 25.9 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 KLO14910.1 - 0.0044 17.4 0.0 0.0088 16.5 0.0 1.4 1 0 0 1 1 1 1 Helically-extended SH3 domain Stevor PF17410.2 KLO14910.1 - 0.015 14.8 2.1 0.028 14.0 2.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Plasmodium_Vir PF05795.11 KLO14910.1 - 0.039 13.4 1.9 0.052 13.0 1.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2207 PF09972.9 KLO14910.1 - 0.051 12.3 0.4 0.066 12.0 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Adeno_E3_CR2 PF02439.15 KLO14910.1 - 0.06 13.1 0.6 0.12 12.2 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MtrF PF09472.10 KLO14910.1 - 0.069 12.6 3.5 0.13 11.6 3.5 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Apt1 PF10351.9 KLO14910.1 - 0.094 11.6 3.1 0.12 11.2 3.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MAP17 PF15807.5 KLO14910.1 - 0.11 12.7 0.2 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Amnionless PF14828.6 KLO14910.1 - 0.16 10.8 6.2 0.094 11.5 0.3 2.0 1 1 1 2 2 2 0 Amnionless SPX PF03105.19 KLO14910.1 - 0.43 10.4 4.6 0.54 10.1 4.6 1.3 1 0 0 1 1 1 0 SPX domain RIFIN PF02009.16 KLO14910.1 - 2.3 8.0 10.8 7.1 6.4 10.8 1.7 1 1 0 1 1 1 0 Rifin Endomucin PF07010.12 KLO14910.1 - 3.5 7.5 39.0 0.3 11.0 33.8 1.8 2 0 0 2 2 2 0 Endomucin FAM163 PF15069.6 KLO14910.1 - 5.6 7.4 9.7 0.3 11.5 0.3 2.9 2 2 0 2 2 2 0 FAM163 family GCOM2 PF15328.6 KLO14910.1 - 6.7 7.0 10.5 10 6.4 10.5 1.3 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 KAR9 PF08580.10 KLO14910.1 - 8.3 4.8 15.4 10 4.6 15.4 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SNF2_N PF00176.23 KLO14911.1 - 2e-32 112.3 0.0 2.1e-25 89.2 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO14911.1 - 0.0023 18.3 0.0 0.0061 16.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pam17 PF08566.10 KLO14912.1 - 6.1e-64 214.8 0.0 7.3e-64 214.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF2833 PF11090.8 KLO14912.1 - 0.15 12.5 0.0 0.36 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) SH3_9 PF14604.6 KLO14913.1 - 9.3e-06 25.4 0.0 2.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KLO14913.1 - 0.00023 20.7 0.0 0.00049 19.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain DUF4381 PF14316.6 KLO14913.1 - 0.12 12.6 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) zf_CCCH_4 PF18345.1 KLO14914.1 - 2.5e-05 24.2 1.6 3.7e-05 23.6 1.6 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KLO14914.1 - 5.6e-05 22.9 1.1 8.6e-05 22.3 1.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KLO14914.1 - 0.002 17.8 1.6 0.0031 17.3 1.6 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KLO14914.1 - 0.0057 17.3 0.1 0.011 16.5 0.1 1.4 1 0 0 1 1 1 1 Torus domain AAA_16 PF13191.6 KLO14915.1 - 1.3e-05 25.6 0.1 0.0032 17.9 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KLO14915.1 - 1.8e-05 24.8 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KLO14915.1 - 2.5e-05 24.4 0.0 6.7e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KLO14915.1 - 2.5e-05 24.7 0.0 5.7e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO14915.1 - 0.00012 22.4 0.1 0.00058 20.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KLO14915.1 - 0.0091 15.4 0.0 3.5 7.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_7 PF12775.7 KLO14915.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KLO14915.1 - 0.024 14.8 0.1 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KLO14915.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Ank_2 PF12796.7 KLO14915.1 - 0.081 13.5 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Mg_chelatase PF01078.21 KLO14915.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KLO14915.1 - 0.14 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KLO14915.1 - 0.18 12.2 0.0 0.53 10.7 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Kelch_6 PF13964.6 KLO14916.1 - 0.0054 17.0 0.4 6.5 7.2 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 KLO14916.1 - 0.28 11.2 5.7 3.3 7.8 0.0 4.2 5 0 0 5 5 5 0 Kelch motif AF-4 PF05110.13 KLO14916.1 - 1 7.4 10.6 1.3 7.0 10.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Acetyltransf_1 PF00583.25 KLO14917.1 - 3.6e-10 40.1 0.1 5.5e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KLO14917.1 - 6.5e-08 32.9 0.1 1.1e-07 32.1 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO14917.1 - 8.3e-06 25.8 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO14917.1 - 0.00047 20.1 0.0 0.00079 19.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KLO14917.1 - 0.00073 19.7 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4500 PF14937.6 KLO14917.1 - 0.1 12.7 0.4 5 7.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) Pkinase_fungal PF17667.1 KLO14918.1 - 5.1e-11 42.0 0.4 1.2e-09 37.4 0.1 2.1 2 0 0 2 2 2 2 Fungal protein kinase IML1 PF12257.8 KLO14919.1 - 3.2e-110 367.8 0.0 1.1e-109 366.0 0.0 1.8 2 0 0 2 2 2 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KLO14919.1 - 1.1e-18 67.0 0.1 2.2e-18 66.1 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3275 PF11679.8 KLO14920.1 - 1.6 8.7 5.4 5.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) DUF4614 PF15391.6 KLO14920.1 - 2.6 8.0 12.1 7.1 6.6 10.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) HNF-1_N PF04814.13 KLO14920.1 - 8.3 7.0 8.7 2.5 8.7 5.5 1.7 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Yip1 PF04893.17 KLO14922.1 - 0.045 13.5 0.0 0.045 13.5 0.0 2.0 2 1 0 2 2 2 0 Yip1 domain PSP PF04046.16 KLO14923.1 - 7.7e-05 22.5 0.2 0.00023 21.0 0.2 1.8 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.23 KLO14923.1 - 0.00025 21.0 1.3 0.00042 20.3 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KLO14923.1 - 0.013 15.3 0.4 0.023 14.5 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KLO14923.1 - 0.016 14.9 0.7 0.03 14.0 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Mito_fiss_reg PF05308.11 KLO14923.1 - 0.058 13.5 1.3 0.083 13.0 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KLO14923.1 - 0.18 11.2 7.3 0.27 10.7 7.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DEC-1_N PF04625.13 KLO14923.1 - 1 8.3 6.7 1.4 7.8 6.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PRIMA1 PF16101.5 KLO14923.1 - 5.6 7.0 11.2 13 5.8 11.2 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 WD40 PF00400.32 KLO14925.1 - 2.6e-81 265.4 32.0 2.3e-08 34.6 0.2 13.8 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO14925.1 - 3.1e-38 130.0 1.4 2.7e-05 24.4 0.0 11.8 2 1 12 14 14 14 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO14925.1 - 5.7e-13 48.5 6.9 0.083 11.8 0.0 8.2 4 2 3 9 9 9 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KLO14925.1 - 2.4e-07 30.4 0.0 0.34 10.2 0.0 4.3 4 1 0 5 5 5 2 WD40-like domain NACHT PF05729.12 KLO14925.1 - 4.8e-07 29.8 0.1 1.3e-06 28.4 0.1 1.8 1 1 0 1 1 1 1 NACHT domain PD40 PF07676.12 KLO14925.1 - 0.0012 18.7 1.7 7.7 6.6 0.0 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KLO14925.1 - 0.003 16.3 0.9 3.2 6.3 0.0 4.6 4 2 2 6 6 6 1 Nucleoporin Nup120/160 AAA_16 PF13191.6 KLO14925.1 - 0.0032 17.9 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Frtz PF11768.8 KLO14925.1 - 0.0061 14.9 0.0 20 3.3 0.0 4.5 4 2 1 5 5 5 0 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 KLO14925.1 - 0.023 13.4 5.4 2 7.1 0.0 4.4 3 1 2 5 5 5 0 Nup133 N terminal like PQQ_2 PF13360.6 KLO14925.1 - 0.035 13.7 4.7 0.18 11.3 0.7 3.6 1 1 1 2 2 2 0 PQQ-like domain AAA PF00004.29 KLO14925.1 - 0.041 14.3 0.0 0.21 12.0 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KLO14925.1 - 0.044 13.0 0.0 0.096 11.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Cytochrom_D1 PF02239.16 KLO14925.1 - 0.059 11.9 0.0 4.9 5.6 0.0 2.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain AAA_22 PF13401.6 KLO14925.1 - 0.15 12.3 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_M29 PF02073.15 KLO14925.1 - 0.17 10.7 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Cyclin_N PF00134.23 KLO14928.1 - 1.5e-12 47.4 0.1 2.5e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KLO14928.1 - 2.3e-06 28.1 0.1 2.3e-06 28.1 0.1 1.9 2 0 0 2 2 2 1 Cyclin DJ-1_PfpI PF01965.24 KLO14931.1 - 1.6e-10 41.1 0.0 1.9e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KLO14931.1 - 3.9e-06 26.7 0.0 6.2e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like LcrG PF07216.12 KLO14931.1 - 0.017 15.0 0.0 0.048 13.6 0.0 1.7 2 0 0 2 2 2 0 LcrG protein DJ-1_PfpI PF01965.24 KLO14932.1 - 1.8e-10 40.9 0.0 4.6e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KLO14932.1 - 0.028 14.1 0.0 0.35 10.5 0.0 2.3 1 1 0 1 1 1 0 ThiJ/PfpI family-like MFP2b PF12150.8 KLO14932.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Cytosolic motility protein tRNA-synt_2c PF01411.19 KLO14933.1 - 1.4e-10 40.4 0.1 1.8e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KLO14933.1 - 0.0029 17.7 0.0 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain zf-RING_2 PF13639.6 KLO14934.1 - 6.3e-06 26.4 1.8 4.6e-05 23.7 0.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KLO14934.1 - 3e-05 23.8 0.9 0.00012 21.9 1.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO14934.1 - 6.7e-05 22.6 3.3 0.00077 19.3 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO14934.1 - 8.5e-05 22.4 3.2 0.00055 19.8 3.4 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KLO14934.1 - 9.4e-05 22.4 1.6 0.00071 19.5 1.7 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KLO14934.1 - 0.00063 19.8 0.1 0.03 14.3 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KLO14934.1 - 0.00084 19.2 0.6 0.00084 19.2 0.6 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KLO14934.1 - 0.0015 18.4 1.7 0.025 14.4 0.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KLO14934.1 - 0.0022 18.2 4.7 0.0077 16.5 4.7 1.9 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KLO14934.1 - 0.0035 17.5 1.3 0.0035 17.5 1.3 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KLO14934.1 - 0.024 14.5 2.4 0.029 14.3 0.6 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KLO14934.1 - 0.044 13.6 2.5 0.072 12.9 0.4 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-MYND PF01753.18 KLO14935.1 - 9.3e-11 41.6 15.3 2e-10 40.6 15.3 1.6 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 KLO14935.1 - 0.0065 17.6 1.2 0.0065 17.6 1.2 1.7 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-Mss51 PF13824.6 KLO14935.1 - 0.097 12.8 5.2 0.28 11.3 5.2 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PolC_DP2 PF03833.13 KLO14935.1 - 0.31 8.9 4.9 0.46 8.3 4.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 KLO14935.1 - 3.1 8.2 13.9 1.5 9.2 10.9 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding DUF1179 PF06678.11 KLO14937.1 - 0.34 10.9 3.0 1 9.4 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) CTD_bind PF04818.13 KLO14940.1 - 1.2e-05 26.0 0.0 4e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. MOZART1 PF12554.8 KLO14940.1 - 0.002 17.9 0.1 0.0035 17.1 0.1 1.4 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated CFIA_Pcf11 PF11526.8 KLO14940.1 - 0.0073 16.8 0.3 0.017 15.6 0.3 1.6 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 Zn-C2H2_12 PF18112.1 KLO14940.1 - 0.041 14.4 2.3 0.76 10.3 0.1 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RVT PF13966.6 KLO14941.1 - 0.0011 19.6 0.2 0.0018 19.0 0.2 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase GAS PF13851.6 KLO14944.1 - 0.009 15.4 3.2 0.014 14.8 2.9 1.4 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 KLO14944.1 - 0.076 13.1 6.5 0.28 11.3 1.0 2.5 2 0 0 2 2 2 0 bZIP transcription factor NEMO PF11577.8 KLO14944.1 - 0.6 10.2 7.4 4.3 7.4 0.8 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Ribosomal_L6 PF00347.23 KLO14945.1 - 7.7e-26 90.6 4.2 5.4e-15 55.8 1.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 FAD_binding_7 PF03441.14 KLO14947.1 - 1.2e-78 263.2 2.9 2.2e-78 262.4 2.9 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KLO14947.1 - 3.6e-37 127.9 0.0 7.2e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase Phosducin PF02114.16 KLO14948.1 - 1.2e-06 27.7 0.3 1.5e-06 27.3 0.3 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KLO14948.1 - 0.0014 18.6 0.4 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Thioredoxin TMPIT PF07851.13 KLO14948.1 - 0.13 11.5 0.6 0.17 11.1 0.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein eRF1_1 PF03463.15 KLO14949.1 - 2e-46 157.2 0.0 2.9e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KLO14949.1 - 2.5e-22 79.6 0.0 3.9e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KLO14949.1 - 7.3e-22 78.0 0.0 1.5e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 DUF680 PF05079.12 KLO14949.1 - 0.12 13.1 1.5 0.56 11.0 1.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF680) HLH PF00010.26 KLO14950.1 - 2.2e-14 53.1 0.4 6.4e-14 51.6 0.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PP1_bind PF15276.6 KLO14950.1 - 0.0059 16.9 0.1 0.043 14.1 0.1 2.5 1 0 0 1 1 1 1 Protein phosphatase 1 binding KASH_CCD PF14662.6 KLO14950.1 - 0.18 11.6 1.0 0.26 11.1 1.0 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DDE_Tnp_1_3 PF13612.6 KLO14950.1 - 0.21 11.6 0.1 0.31 11.0 0.1 1.2 1 0 0 1 1 1 0 Transposase DDE domain AAA PF00004.29 KLO14951.1 - 7.9e-08 32.8 0.0 6.2e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KLO14951.1 - 0.00053 20.0 0.0 0.079 12.9 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KLO14951.1 - 0.0043 17.4 0.0 0.0094 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KLO14951.1 - 0.006 15.8 0.0 0.0083 15.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KLO14951.1 - 0.0068 16.4 0.0 0.028 14.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KLO14951.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 KLO14951.1 - 0.034 13.2 0.0 0.047 12.7 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KLO14951.1 - 0.049 12.9 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KLO14951.1 - 0.099 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KLO14951.1 - 0.11 13.0 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KLO14951.1 - 0.18 12.1 0.0 0.52 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KLO14951.1 - 0.25 11.1 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cupin_8 PF13621.6 KLO14953.1 - 1.2e-60 205.4 0.0 1.4e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KLO14953.1 - 0.00027 20.5 0.0 0.0005 19.6 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KLO14953.1 - 0.00063 20.2 0.0 0.0021 18.5 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KLO14953.1 - 0.0016 18.1 0.2 0.014 15.1 0.0 2.3 2 0 0 2 2 2 1 Cupin domain Med20 PF08612.11 KLO14954.1 - 3.8e-10 39.5 0.1 3e-09 36.6 0.1 2.0 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex ORC4_C PF14629.6 KLO14955.1 - 1.2e-31 109.8 0.0 3e-31 108.5 0.0 1.7 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KLO14955.1 - 1.3e-16 61.5 0.1 3e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KLO14955.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KLO14955.1 - 0.0011 19.2 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KLO14955.1 - 0.018 15.5 0.0 0.088 13.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KLO14955.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KLO14955.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KLO14955.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 NTPase BCDHK_Adom3 PF10436.9 KLO14956.1 - 3.9e-42 143.8 0.0 5.6e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KLO14956.1 - 2.4e-07 31.3 0.0 1.7e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-RING_2 PF13639.6 KLO14959.1 - 1.2e-07 32.0 3.3 1.5e-06 28.4 0.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KLO14959.1 - 3.9e-07 29.8 2.9 3.1e-06 26.9 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO14959.1 - 1.2e-06 28.2 0.3 3e-06 27.0 0.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO14959.1 - 1.6e-06 28.0 0.1 5.2e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KLO14959.1 - 1.3e-05 25.0 1.2 0.00015 21.7 0.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KLO14959.1 - 1.9e-05 24.4 1.1 0.00029 20.6 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KLO14959.1 - 2.3e-05 24.6 3.1 6.7e-05 23.1 3.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KLO14959.1 - 0.00033 20.4 1.3 0.0075 16.1 0.2 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C2HC5 PF06221.13 KLO14959.1 - 0.023 14.7 0.7 0.05 13.6 0.1 1.7 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-Nse PF11789.8 KLO14959.1 - 0.024 14.5 0.4 0.075 12.9 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_9 PF14369.6 KLO14959.1 - 0.033 14.4 3.8 1.2 9.4 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon zf-RING_4 PF14570.6 KLO14959.1 - 0.037 13.8 4.7 0.071 12.9 2.2 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KLO14959.1 - 0.038 14.1 4.6 0.073 13.2 1.0 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FAM199X PF15814.5 KLO14959.1 - 0.045 12.8 1.4 0.067 12.2 1.4 1.3 1 0 0 1 1 1 0 Protein family FAM199X BAG6 PF12057.8 KLO14959.1 - 0.057 13.1 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 BCL2-associated athanogene 6 zf-ANAPC11 PF12861.7 KLO14959.1 - 0.14 12.2 0.2 0.8 9.8 0.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 KLO14959.1 - 0.16 11.6 0.6 0.72 9.6 0.1 1.9 2 0 0 2 2 2 0 P-11 zinc finger Spo12 PF05032.12 KLO14960.1 - 1e-15 57.3 5.1 2.7e-15 55.9 5.1 1.8 1 0 0 1 1 1 1 Spo12 family Pheromone PF08015.11 KLO14960.1 - 9.5 7.3 10.3 1.6 9.8 6.2 1.8 2 1 0 2 2 2 0 Fungal mating-type pheromone Ras PF00071.22 KLO14961.1 - 3.1e-44 150.4 0.1 3.6e-44 150.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO14961.1 - 4e-17 62.6 0.0 5.9e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO14961.1 - 4.3e-08 32.8 0.0 5.8e-08 32.4 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KLO14961.1 - 0.00051 20.1 0.0 0.00079 19.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KLO14961.1 - 0.00093 18.7 0.1 0.0017 17.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KLO14961.1 - 0.0014 18.6 0.1 0.73 9.7 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KLO14961.1 - 0.0028 18.0 0.0 0.0035 17.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KLO14961.1 - 0.005 16.9 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 KLO14961.1 - 0.0054 16.3 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B TniB PF05621.11 KLO14961.1 - 0.03 13.7 0.0 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein TRIF-NTD PF17798.1 KLO14961.1 - 0.032 14.4 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 TRIF N-terminal domain ATPase_2 PF01637.18 KLO14961.1 - 0.092 12.6 0.2 0.12 12.3 0.2 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DLIC PF05783.11 KLO14961.1 - 0.096 11.5 0.0 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.9 KLO14961.1 - 0.11 12.2 0.2 0.25 11.1 0.2 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Mannosidase_ig PF17786.1 KLO14962.1 - 2.3e-15 57.0 0.2 5.9e-15 55.7 0.2 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KLO14962.1 - 0.00016 22.3 0.0 0.00064 20.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KLO14962.1 - 0.012 15.4 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 Ig-fold domain Sugar_tr PF00083.24 KLO14963.1 - 5.1e-87 292.6 14.7 5.9e-87 292.4 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO14963.1 - 2.4e-38 132.0 30.4 4.7e-35 121.1 16.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KLO14963.1 - 2e-05 23.4 17.8 0.022 13.4 3.2 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein TRI12 PF06609.13 KLO14963.1 - 0.001 17.6 1.7 0.0017 16.9 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KLO14963.1 - 0.014 13.8 5.2 0.92 7.8 0.1 3.3 3 1 1 4 4 4 0 Transmembrane secretion effector DUF3792 PF12670.7 KLO14963.1 - 0.24 11.6 15.6 0.59 10.3 2.0 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF3792) BT1 PF03092.16 KLO14963.1 - 0.57 8.3 4.8 0.061 11.5 0.3 1.6 2 0 0 2 2 2 0 BT1 family FmiP_Thoc5 PF09766.9 KLO14964.1 - 1.2e-29 103.8 7.9 1.6e-29 103.4 7.9 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 T3SSipB PF16535.5 KLO14964.1 - 0.0011 19.5 0.9 0.0011 19.5 0.9 2.2 2 0 0 2 2 2 1 Type III cell invasion protein SipB TMF_DNA_bd PF12329.8 KLO14964.1 - 0.0041 17.1 3.7 0.0041 17.1 3.7 2.3 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding TssO PF17561.2 KLO14964.1 - 0.0089 16.1 1.5 0.026 14.6 1.1 1.9 2 1 0 2 2 2 1 Type VI secretion system, TssO GCIP PF13324.6 KLO14964.1 - 0.047 13.3 5.0 0.075 12.6 5.0 1.6 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting Cons_hypoth95 PF03602.15 KLO14964.1 - 0.13 11.9 0.6 0.24 11.0 0.6 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Seryl_tRNA_N PF02403.22 KLO14964.1 - 0.37 11.1 8.2 4.8 7.4 2.4 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Mod_r PF07200.13 KLO14964.1 - 0.79 9.8 12.5 0.3 11.2 4.9 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Csm1_N PF18504.1 KLO14964.1 - 2 8.8 8.7 0.52 10.7 4.1 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain FlaC_arch PF05377.11 KLO14964.1 - 2.4 8.6 6.2 0.78 10.2 1.6 2.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 KLO14964.1 - 9.3 5.5 13.1 1.6 7.9 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) UQ_con PF00179.26 KLO14965.1 - 4.1e-38 130.2 0.1 5.2e-38 129.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Arm-DNA-bind_4 PF14657.6 KLO14965.1 - 0.029 14.1 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 Arm DNA-binding domain RWD PF05773.22 KLO14965.1 - 0.077 13.3 0.1 0.12 12.7 0.1 1.4 1 1 0 1 1 1 0 RWD domain GST_N_3 PF13417.6 KLO14966.1 - 1.3e-11 44.8 0.0 3.6e-11 43.3 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO14966.1 - 3.3e-11 43.3 0.0 5.5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO14966.1 - 0.00094 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KLO14966.1 - 0.00094 19.2 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO14966.1 - 0.0025 18.0 0.0 0.0058 16.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KLO14966.1 - 0.01 16.2 0.0 0.089 13.1 0.0 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CT_C_D PF02682.16 KLO14966.1 - 0.06 13.1 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D F-box-like PF12937.7 KLO14967.1 - 0.032 14.1 0.0 0.12 12.3 0.0 2.1 1 0 0 1 1 1 0 F-box-like Ecm33 PF12454.8 KLO14968.1 - 0.24 11.6 0.3 0.24 11.6 0.3 2.8 4 0 0 4 4 4 0 GPI-anchored cell wall organization protein Abhydrolase_5 PF12695.7 KLO14970.1 - 0.19 11.5 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family MARVEL PF01284.23 KLO14971.1 - 0.011 15.7 11.3 0.017 15.1 11.3 1.3 1 0 0 1 1 1 0 Membrane-associating domain PhaG_MnhG_YufB PF03334.14 KLO14971.1 - 6.2 7.1 11.2 0.39 11.0 4.0 2.4 2 1 0 2 2 2 0 Na+/H+ antiporter subunit MARVEL PF01284.23 KLO14972.1 - 0.12 12.4 16.0 0.59 10.2 15.1 2.2 1 1 1 2 2 2 0 Membrane-associating domain MIG-14_Wnt-bd PF06664.12 KLO14972.1 - 0.69 9.1 10.5 5.9 6.0 10.5 1.9 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion HILPDA PF15220.6 KLO14972.1 - 1.5 9.0 5.0 7.9 6.7 0.1 3.1 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated MASE5 PF17178.4 KLO14972.1 - 4.4 7.1 10.8 0.76 9.6 5.1 2.3 2 1 1 3 3 3 0 Membrane-associated sensor UL42 PF17638.2 KLO14972.1 - 5.4 7.0 7.8 3.8e+02 1.0 9.0 3.1 2 1 0 2 2 2 0 HCMV UL42 AMP-binding PF00501.28 KLO14973.1 - 1.8e-40 138.8 0.0 2.5e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KLO14973.1 - 4.7e-06 26.4 1.9 1e-05 25.3 1.9 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KLO14973.1 - 0.0016 19.4 0.0 0.0037 18.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1754 PF08555.10 KLO14974.1 - 0.086 13.7 0.3 0.13 13.1 0.3 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Ecm33 PF12454.8 KLO14975.1 - 0.24 11.6 0.3 0.24 11.6 0.3 2.6 3 0 0 3 3 3 0 GPI-anchored cell wall organization protein F-box-like PF12937.7 KLO14976.1 - 0.0014 18.5 0.2 0.0032 17.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like Nup84_Nup100 PF04121.13 KLO14976.1 - 0.084 11.0 0.1 0.12 10.4 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 F-box-like PF12937.7 KLO14977.1 - 0.0047 16.8 0.1 0.012 15.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like Chitin_synth_1 PF01644.17 KLO14978.1 - 6.4e-65 218.1 0.0 1e-64 217.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KLO14978.1 - 2.3e-29 101.2 0.0 5.2e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KLO14978.1 - 8.6e-24 84.0 0.0 1.1e-19 70.4 0.0 2.5 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KLO14978.1 - 5e-09 36.4 7.4 7.7e-09 35.7 0.0 2.4 1 1 1 2 2 2 1 Glycosyl transferase family group 2 F-box-like PF12937.7 KLO14979.1 - 5.8e-06 26.1 1.8 2.7e-05 24.0 0.0 3.0 3 0 0 3 3 3 1 F-box-like Ribosomal_L7Ae PF01248.26 KLO14980.1 - 9.7e-25 86.1 0.4 1.6e-24 85.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3759 PF12585.8 KLO14981.1 - 2.1e-36 123.8 7.2 2.7e-36 123.4 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3759 PF12585.8 KLO14982.1 - 9e-37 125.0 6.2 1e-36 124.8 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Pkinase_fungal PF17667.1 KLO14985.1 - 1e-38 133.2 0.0 1.2e-32 113.2 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase Plavaka PF18759.1 KLO14986.1 - 2.5e-13 49.9 0.0 3.1e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KLO14987.1 - 1.4e-28 100.1 0.1 1.9e-28 99.7 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase Snf7 PF03357.21 KLO14988.1 - 1.3e-32 112.7 17.3 1.3e-32 112.7 17.3 2.0 1 1 1 2 2 2 1 Snf7 BRCC36_C PF18110.1 KLO14988.1 - 0.081 13.1 2.6 1.3 9.3 2.2 2.8 1 1 0 1 1 1 0 BRCC36 C-terminal helical domain NIF PF03031.18 KLO14989.1 - 7.9e-52 175.2 0.0 1.2e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CLPTM1 PF05602.12 KLO14990.1 - 1e-149 499.2 0.0 1.2e-149 499.0 0.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KLO14990.1 - 0.0005 19.8 3.6 0.00071 19.3 0.3 2.6 3 0 0 3 3 3 1 PQ loop repeat 2TM PF13239.6 KLO14990.1 - 1.3 9.4 5.8 0.69 10.3 1.2 2.8 2 1 0 2 2 2 0 2TM domain zf-MYND PF01753.18 KLO14993.1 - 4.5e-10 39.5 14.0 4.5e-10 39.5 14.0 1.7 2 0 0 2 2 2 1 MYND finger PolC_DP2 PF03833.13 KLO14993.1 - 0.25 9.1 3.9 0.39 8.5 3.9 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 KLO14993.1 - 0.4 11.0 10.4 0.99 9.8 10.4 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KLO14993.1 - 1.1 9.4 4.6 2.2 8.5 4.6 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 RNF220 PF15926.5 KLO14994.1 - 6e-14 52.3 16.6 2.6e-11 43.6 16.6 2.6 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 KLO14994.1 - 6e-09 35.6 15.2 6e-09 35.6 15.2 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO14994.1 - 6.2e-06 26.0 20.8 0.0001 22.0 12.3 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO14994.1 - 8.6e-05 22.3 14.4 8.6e-05 22.3 14.4 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO14994.1 - 0.00014 21.8 12.6 0.00014 21.8 12.6 3.3 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 KLO14994.1 - 0.00091 19.5 16.3 0.00091 19.5 16.3 3.3 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KLO14994.1 - 0.0011 19.0 8.7 0.0011 19.0 8.7 3.4 3 2 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KLO14994.1 - 0.021 14.7 21.4 0.57 10.1 10.9 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 KLO14994.1 - 0.2 12.0 8.4 2.5 8.5 0.0 3.8 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding FUSC PF04632.12 KLO14994.1 - 0.24 9.9 1.9 0.34 9.4 1.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Zn-C2H2_12 PF18112.1 KLO14994.1 - 1.2 9.7 14.5 9.8 6.7 0.7 3.6 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Rad50_zn_hook PF04423.14 KLO14994.1 - 1.5 8.8 7.1 27 4.7 0.1 3.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-WRNIP1_ubi PF18279.1 KLO14994.1 - 2.2 9.1 4.9 74 4.3 0.1 3.4 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain PRP21_like_P PF12230.8 KLO14994.1 - 2.2 8.1 6.9 0.32 10.8 0.2 2.6 2 1 1 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein Complex1_LYR PF05347.15 KLO14996.1 - 1.2e-10 41.3 1.5 1.9e-10 40.6 1.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) AFG1_ATPase PF03969.16 KLO14997.1 - 1.1e-104 350.2 0.1 1.6e-100 336.5 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KLO14997.1 - 2.1e-05 25.0 0.4 0.031 14.7 0.0 2.9 1 1 1 3 3 3 2 AAA ATPase domain AAA PF00004.29 KLO14997.1 - 0.00028 21.3 0.0 0.00082 19.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO14997.1 - 0.0016 18.7 0.0 0.0098 16.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KLO14997.1 - 0.039 13.5 0.1 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region UvrD-helicase PF00580.21 KLO14997.1 - 0.044 13.3 0.0 0.23 10.9 0.0 2.1 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain TniB PF05621.11 KLO14997.1 - 0.067 12.6 0.1 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein DUF2076 PF09849.9 KLO14997.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) JAB PF01398.21 KLO14998.1 - 1.4e-21 76.6 0.2 2.4e-21 75.9 0.2 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KLO14998.1 - 9e-18 64.7 0.2 1.7e-17 63.9 0.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Tom7 PF08038.12 KLO14999.1 - 1.2e-18 66.4 0.2 1.5e-18 66.1 0.2 1.1 1 0 0 1 1 1 1 TOM7 family rve PF00665.26 KLO15002.1 - 0.00047 20.3 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.18 KLO15002.1 - 0.012 15.8 0.0 4.9 7.5 0.0 2.4 1 1 1 2 2 2 0 Transposase HTH_21 PF13276.6 KLO15002.1 - 0.024 14.8 0.8 2.8 8.1 0.1 2.6 1 1 1 2 2 2 0 HTH-like domain Alpha_kinase PF02816.18 KLO15003.1 - 4.4e-11 43.2 0.6 2.1e-10 41.0 0.1 2.1 2 0 0 2 2 2 1 Alpha-kinase family zf-H3C2 PF16721.5 KLO15003.1 - 0.13 12.6 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding TackOD1 PF18551.1 KLO15003.1 - 0.59 9.8 6.1 1.3 8.6 6.1 1.5 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-A20 PF01754.16 KLO15003.1 - 0.78 9.7 3.5 1.9 8.5 3.5 1.6 1 0 0 1 1 1 0 A20-like zinc finger FYVE_2 PF02318.16 KLO15003.1 - 0.91 9.7 9.7 34 4.7 9.7 2.5 1 1 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 KLO15003.1 - 1.3 9.1 7.1 5.1 7.2 6.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon FYVE PF01363.21 KLO15003.1 - 3.1 8.0 5.8 6.9 6.9 5.8 1.6 1 0 0 1 1 1 0 FYVE zinc finger HTH_Tnp_ISL3 PF13542.6 KLO15007.1 - 0.069 12.6 0.3 0.36 10.3 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 PBP1_TM PF14812.6 KLO15010.1 - 0.016 15.5 3.0 0.016 15.5 3.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PRR20 PF15708.5 KLO15010.1 - 0.08 12.8 3.2 0.19 11.6 3.2 1.6 1 0 0 1 1 1 0 Proline-rich protein family 20 SGP PF17228.2 KLO15010.1 - 0.4 11.5 6.6 1.4 9.8 6.6 1.9 1 1 0 1 1 1 0 Sulphur globule protein DDE_3 PF13358.6 KLO15011.1 - 1.4e-09 37.9 0.0 2.4e-09 37.1 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO15012.1 - 1.4e-09 37.9 0.0 1.5e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 KLO15013.1 - 9.4e-05 22.0 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_29 PF13551.6 KLO15013.1 - 0.057 13.4 0.6 0.088 12.8 0.1 1.5 2 0 0 2 2 2 0 Winged helix-turn helix DUF1670 PF07900.11 KLO15013.1 - 0.095 12.0 0.3 0.12 11.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) DUF4907 PF16250.5 KLO15013.1 - 0.15 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4907) MeaB PF03308.16 KLO15014.1 - 4.3 6.2 7.5 5.3 5.9 7.5 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TPR_12 PF13424.6 KLO15015.1 - 3.6e-08 33.6 27.4 0.0046 17.2 1.3 7.4 4 2 4 8 8 8 6 Tetratricopeptide repeat SNAP PF14938.6 KLO15015.1 - 2.4e-05 23.9 14.6 0.00056 19.4 0.7 3.6 2 1 1 4 4 4 3 Soluble NSF attachment protein, SNAP AAA_16 PF13191.6 KLO15015.1 - 0.00044 20.7 2.0 0.0092 16.4 0.9 3.2 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KLO15015.1 - 0.001 18.3 0.0 0.0022 17.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 KLO15015.1 - 0.0058 16.7 24.8 1.1 9.5 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat DUF2225 PF09986.9 KLO15015.1 - 0.031 14.0 0.6 0.32 10.7 0.2 2.6 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF4810 PF16068.5 KLO15015.1 - 0.035 14.6 0.4 0.35 11.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) UPF0180 PF03698.13 KLO15015.1 - 0.066 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) TPR_7 PF13176.6 KLO15015.1 - 7.8 6.8 6.9 45 4.4 0.3 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PMM PF03332.13 KLO15016.1 - 5.1e-79 265.1 0.0 6.4e-79 264.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KLO15016.1 - 0.0006 19.6 0.0 0.25 11.0 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KLO15016.1 - 0.1 12.1 0.0 10 5.6 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase zf-MYND PF01753.18 KLO15017.1 - 2.3e-08 34.0 11.2 2.3e-08 34.0 11.2 1.9 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 KLO15018.1 - 7.1e-08 32.4 11.1 1.3e-07 31.6 11.1 1.4 1 0 0 1 1 1 1 MYND finger DUF89 PF01937.19 KLO15019.1 - 4.4e-107 358.1 0.0 5e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Antimicrobial21 PF14861.6 KLO15020.1 - 2.8 7.7 8.3 0.075 12.8 1.7 1.9 2 0 0 2 2 2 0 Plant antimicrobial peptide NB-ARC PF00931.22 KLO15022.1 - 2.1e-05 23.9 0.0 3.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 KLO15022.1 - 0.00021 21.5 33.2 0.012 15.9 1.4 7.1 5 2 4 9 9 9 4 Tetratricopeptide repeat AAA_16 PF13191.6 KLO15022.1 - 0.0003 21.2 0.5 0.002 18.5 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain SNAP PF14938.6 KLO15022.1 - 0.0016 17.9 14.1 0.015 14.7 0.3 3.3 3 0 0 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 KLO15022.1 - 0.0076 16.3 20.8 1.1 9.6 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat NACHT PF05729.12 KLO15022.1 - 0.073 13.0 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain RPN7 PF10602.9 KLO15022.1 - 0.2 11.3 3.2 1.9 8.1 0.1 3.2 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_16 PF13432.6 KLO15022.1 - 3.2 8.5 21.4 6.7 7.5 0.2 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Asp PF00026.23 KLO15024.1 - 1.7e-47 162.4 7.8 5.9e-47 160.6 7.8 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO15024.1 - 5.9e-09 36.4 6.1 0.00017 21.9 0.1 3.3 1 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KLO15024.1 - 0.014 16.0 3.4 0.094 13.4 1.0 2.7 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 KLO15024.1 - 0.077 12.8 1.2 0.32 10.8 0.1 2.3 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal ABC_membrane PF00664.23 KLO15025.1 - 3.4e-48 164.7 24.1 8.5e-34 117.5 4.5 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KLO15025.1 - 1.4e-47 161.6 0.0 6.5e-28 98.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KLO15025.1 - 9e-08 31.8 2.3 0.014 14.8 0.0 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KLO15025.1 - 1.1e-05 25.7 5.1 0.043 13.9 0.7 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_16 PF13191.6 KLO15025.1 - 2.2e-05 24.9 4.0 0.11 12.9 0.2 3.1 2 2 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 KLO15025.1 - 2.8e-05 23.3 3.4 0.051 12.6 0.3 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KLO15025.1 - 6.1e-05 22.7 2.7 0.015 15.0 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KLO15025.1 - 0.00011 22.8 2.0 0.0098 16.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KLO15025.1 - 0.00027 20.6 0.2 0.91 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KLO15025.1 - 0.00041 20.1 0.0 0.26 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KLO15025.1 - 0.0015 18.7 0.2 0.082 13.0 0.0 2.4 2 0 0 2 2 2 1 Dynamin family NACHT PF05729.12 KLO15025.1 - 0.0024 17.8 0.9 1.7 8.5 0.0 2.8 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 KLO15025.1 - 0.0049 16.9 0.6 4.1 7.5 0.2 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KLO15025.1 - 0.0063 15.9 0.7 0.75 9.1 0.2 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 KLO15025.1 - 0.0077 15.2 1.6 0.39 9.6 0.1 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 KLO15025.1 - 0.012 15.9 7.8 2 8.7 1.6 3.2 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KLO15025.1 - 0.013 15.6 0.3 9.2 6.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF2075 PF09848.9 KLO15025.1 - 0.014 14.7 2.4 0.81 8.9 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_21 PF13304.6 KLO15025.1 - 0.024 14.5 7.7 2.3 8.0 0.2 4.4 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KLO15025.1 - 0.024 13.9 1.9 1.8 7.8 0.2 2.5 2 0 0 2 2 2 0 Zeta toxin CbiA PF01656.23 KLO15025.1 - 0.027 14.5 0.8 1.6 8.8 0.0 3.4 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KLO15025.1 - 0.031 14.8 0.6 13 6.4 0.3 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KLO15025.1 - 0.045 14.2 0.0 12 6.3 0.0 3.6 4 1 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 KLO15025.1 - 0.11 12.3 2.8 1 9.1 0.7 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase Pox_A32 PF04665.12 KLO15025.1 - 0.11 11.9 1.2 1.2 8.5 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein MobB PF03205.14 KLO15025.1 - 0.11 12.4 1.6 0.92 9.4 0.3 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 KLO15025.1 - 0.14 11.6 0.6 18 4.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 KLO15025.1 - 0.15 12.0 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit cobW PF02492.19 KLO15025.1 - 0.26 10.9 4.7 5.4 6.6 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 KLO15025.1 - 0.44 10.3 1.5 5.8 6.6 0.0 2.5 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 KLO15025.1 - 0.59 10.0 2.0 3.7 7.4 0.2 2.5 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 KLO15025.1 - 1.3 8.9 5.3 3.2 7.7 0.3 3.0 3 0 0 3 3 3 0 NTPase AAA_24 PF13479.6 KLO15025.1 - 2.6 7.7 3.5 2.3 7.9 0.5 2.4 2 1 0 2 2 2 0 AAA domain Aldedh PF00171.22 KLO15026.1 - 3.8e-122 408.1 0.0 4.5e-122 407.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribonuclease_T2 PF00445.18 KLO15027.1 - 1.6e-37 129.5 0.1 2.2e-37 129.0 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family ACT_7 PF13840.6 KLO15029.1 - 5.4e-18 64.5 0.0 1e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain Mito_carr PF00153.27 KLO15030.1 - 1.6e-52 175.4 0.3 2.7e-18 65.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_6 PF08036.11 KLO15030.1 - 0.11 12.6 0.1 7.1 6.8 0.0 3.0 3 0 0 3 3 3 0 Diapausin family of antimicrobial peptide PXA PF02194.15 KLO15031.1 - 7.6e-45 153.1 0.8 1.9e-44 151.8 0.2 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KLO15031.1 - 8.1e-30 103.7 0.0 3.1e-29 101.8 0.0 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KLO15031.1 - 1.5e-15 57.2 0.0 3.9e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KLO15031.1 - 7.6e-09 35.9 0.1 1.8e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Prenyltrans PF00432.21 KLO15031.1 - 0.018 14.8 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Isy1 PF06246.12 KLO15031.1 - 0.027 14.1 0.2 0.14 11.7 0.1 2.2 2 0 0 2 2 2 0 Isy1-like splicing family Fer4_21 PF14697.6 KLO15033.1 - 0.036 14.2 1.0 0.076 13.2 1.0 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain IP_trans PF02121.18 KLO15033.1 - 0.19 11.3 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein CBM_21 PF03370.13 KLO15034.1 - 5.7e-22 78.0 0.0 1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KLO15034.1 - 5.7e-06 26.8 0.0 2.1e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CbiJ PF02571.14 KLO15035.1 - 0.061 12.8 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Pacifastin_I PF05375.13 KLO15037.1 - 0.055 13.2 1.3 0.082 12.6 0.1 2.0 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) Polysacc_deac_1 PF01522.21 KLO15038.1 - 1.8e-05 24.6 0.1 6.8e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase Myosin_head PF00063.21 KLO15040.1 - 2.2e-237 789.6 0.6 2.8e-237 789.2 0.6 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KLO15040.1 - 5.5e-53 179.4 0.1 1.2e-52 178.3 0.1 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding UNC45-central PF11701.8 KLO15040.1 - 5e-28 98.0 0.4 2.9e-27 95.5 0.5 2.3 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central SH3_2 PF07653.17 KLO15040.1 - 6.6e-09 35.3 0.0 1.5e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KLO15040.1 - 1.5e-08 34.1 0.9 2.8e-08 33.2 0.9 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KLO15040.1 - 4.6e-08 32.8 0.1 1.2e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KLO15040.1 - 0.0014 18.9 0.4 0.003 17.8 0.4 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_16 PF13191.6 KLO15040.1 - 0.044 14.2 0.0 0.23 11.9 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 KLO15040.1 - 0.049 13.2 0.8 11 5.5 0.1 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 KLO15040.1 - 0.086 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF229 PF02995.17 KLO15040.1 - 0.13 10.8 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) HEAT PF02985.22 KLO15040.1 - 0.15 12.4 0.5 6.9 7.2 0.1 3.3 2 0 0 2 2 2 0 HEAT repeat NACHT PF05729.12 KLO15040.1 - 0.17 11.8 0.1 0.43 10.5 0.1 1.7 1 0 0 1 1 1 0 NACHT domain Gcd10p PF04189.13 KLO15041.1 - 2.3e-68 230.5 0.0 5e-68 229.4 0.0 1.4 1 1 0 1 1 1 1 Gcd10p family DUF2031 PF09592.10 KLO15041.1 - 0.022 14.3 0.8 0.036 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) GDI PF00996.18 KLO15042.1 - 2.1e-220 731.7 0.6 2.4e-220 731.5 0.6 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Methyltransf_25 PF13649.6 KLO15043.1 - 1.9e-15 57.3 0.0 6.9e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO15043.1 - 5.3e-13 49.4 0.0 3.9e-12 46.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO15043.1 - 1.2e-09 38.2 0.0 2.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO15043.1 - 3e-08 33.6 0.0 5.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO15043.1 - 3.4e-08 33.1 0.0 5.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KLO15043.1 - 7e-08 32.0 0.0 1.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KLO15043.1 - 6.3e-07 30.1 0.0 2.2e-06 28.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KLO15043.1 - 0.0003 20.3 0.0 0.016 14.6 0.0 2.6 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KLO15043.1 - 0.0015 18.7 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase AbiJ_NTD5 PF18865.1 KLO15043.1 - 0.034 13.9 0.2 0.093 12.5 0.2 1.7 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 Methyltransf_29 PF03141.16 KLO15043.1 - 0.034 12.7 0.0 0.062 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 KLO15043.1 - 0.057 13.0 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KLO15043.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Rav1p_C PF12234.8 KLO15044.1 - 4.1e-199 663.1 0.0 5.1e-199 662.8 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal Fasciclin PF02469.22 KLO15045.1 - 6.2e-65 217.2 0.0 2.3e-15 56.9 0.0 5.4 5 0 0 5 5 5 5 Fasciclin domain SprB PF13573.6 KLO15045.1 - 0.049 13.4 0.2 0.13 12.0 0.2 1.7 1 0 0 1 1 1 0 SprB repeat Acetyltransf_10 PF13673.7 KLO15046.1 - 2.7e-06 27.3 0.0 4.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO15046.1 - 1.9e-05 25.0 0.0 3.7e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO15046.1 - 0.00047 20.4 0.0 0.00075 19.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KLO15046.1 - 0.0071 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO15046.1 - 0.0087 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein p450 PF00067.22 KLO15048.1 - 6.4e-75 252.7 0.0 7.3e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Inhibitor_I10 PF12559.8 KLO15048.1 - 0.015 15.5 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Serine endopeptidase inhibitors DNA_pol3_delta2 PF13177.6 KLO15048.1 - 0.026 14.3 0.1 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit dCMP_cyt_deam_1 PF00383.23 KLO15050.1 - 7.7e-26 89.9 1.9 1.2e-25 89.3 1.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KLO15050.1 - 6.9e-11 42.0 0.5 2e-10 40.6 0.3 1.8 2 0 0 2 2 2 1 MafB19-like deaminase AAA_18 PF13238.6 KLO15050.1 - 0.02 15.5 0.0 0.057 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KLO15050.1 - 0.031 14.4 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KLO15050.1 - 0.046 13.7 0.1 0.14 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KLO15050.1 - 0.063 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 KLO15050.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Dynamin family SNAD4 PF18750.1 KLO15050.1 - 0.31 11.2 2.9 0.46 10.6 1.6 2.0 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 PhzC-PhzF PF02567.16 KLO15051.1 - 5.8e-49 167.1 0.0 6.7e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DUF5300 PF17224.3 KLO15051.1 - 0.05 13.9 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) UQ_con PF00179.26 KLO15052.1 - 1.2e-20 73.5 0.0 2.1e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4537 PF15057.6 KLO15052.1 - 0.005 16.9 0.2 0.063 13.3 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) UEV PF05743.13 KLO15052.1 - 0.17 11.8 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 UEV domain SKN1 PF03935.15 KLO15053.1 - 2.1e-192 640.0 1.1 2.7e-192 639.6 1.1 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) NAT PF04768.13 KLO15055.1 - 4e-35 121.0 0.1 1.3e-20 73.7 0.0 2.2 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase Mito_carr PF00153.27 KLO15056.1 - 5.1e-64 212.2 6.0 9.3e-22 76.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PP2C PF00481.21 KLO15057.1 - 1.9e-22 80.2 0.0 6.2e-21 75.2 0.0 2.5 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 KLO15057.1 - 2.5e-09 37.1 0.0 4.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KLO15057.1 - 2.3e-06 27.6 0.0 0.041 13.8 0.0 2.6 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) MMR_HSR1 PF01926.23 KLO15058.1 - 1.7e-15 57.1 0.0 5.5e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KLO15058.1 - 1.2e-07 31.4 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KLO15058.1 - 0.00079 19.5 1.0 0.06 13.4 0.2 3.4 3 1 1 4 4 4 1 Dynamin family RsgA_GTPase PF03193.16 KLO15058.1 - 0.001 19.0 0.0 0.0033 17.4 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KLO15058.1 - 0.029 13.7 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 KLO15058.1 - 0.086 13.1 0.1 0.34 11.1 0.1 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KLO15058.1 - 0.12 11.7 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 KLO15058.1 - 0.12 12.7 0.0 1 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain BCL_N PF04714.13 KLO15059.1 - 0.00079 19.4 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 BCL7, N-terminal conserver region FmiP_Thoc5 PF09766.9 KLO15059.1 - 0.074 12.3 0.3 0.11 11.7 0.1 1.3 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 MRP-S25 PF13741.6 KLO15060.1 - 8.8e-46 156.3 7.6 1.1e-44 152.7 7.6 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KLO15060.1 - 0.00069 19.9 2.2 0.0038 17.5 1.8 2.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 DUF3197 PF11432.8 KLO15060.1 - 0.095 12.6 0.4 0.18 11.7 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3197) ICL PF00463.21 KLO15061.1 - 2.2e-186 620.4 0.2 2.6e-186 620.2 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KLO15061.1 - 1.2e-09 38.0 1.3 4.6e-09 36.1 0.1 2.3 3 0 0 3 3 3 1 Phosphoenolpyruvate phosphomutase Med11 PF10280.9 KLO15062.1 - 3.6e-11 43.7 0.1 4.7e-11 43.3 0.1 1.3 1 1 0 1 1 1 1 Mediator complex protein TBCA PF02970.16 KLO15063.1 - 7.7e-13 48.6 9.3 7.7e-13 48.6 9.3 1.9 1 1 1 2 2 2 1 Tubulin binding cofactor A DUF1664 PF07889.12 KLO15063.1 - 0.047 13.7 5.0 0.072 13.1 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 KLO15063.1 - 0.058 13.7 0.7 0.058 13.7 0.7 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DHR10 PF18595.1 KLO15063.1 - 0.1 12.6 11.1 0.48 10.5 1.5 2.7 1 1 1 3 3 3 0 Designed helical repeat protein 10 domain HIP1_clath_bdg PF16515.5 KLO15063.1 - 0.43 11.2 9.6 0.83 10.3 0.7 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 KLO15063.1 - 0.49 9.2 12.3 0.65 8.8 12.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 KLO15063.1 - 3.4 6.8 5.8 3.7 6.7 5.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein HLH PF00010.26 KLO15066.1 - 2.9e-10 39.9 5.0 7.2e-10 38.7 1.7 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2897 PF11446.8 KLO15067.1 - 0.19 11.6 0.2 0.39 10.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) HLH PF00010.26 KLO15068.1 - 3.7e-11 42.8 1.7 3.7e-11 42.8 1.7 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain FTA4 PF13093.6 KLO15068.1 - 0.0013 18.7 0.2 0.0019 18.1 0.2 1.4 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CENP-F_leu_zip PF10473.9 KLO15068.1 - 0.036 14.1 2.8 0.062 13.3 2.8 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Wtap PF17098.5 KLO15068.1 - 0.066 13.2 2.4 0.16 11.9 2.4 1.7 1 0 0 1 1 1 0 WTAP/Mum2p family FapA PF03961.13 KLO15068.1 - 0.23 10.0 1.4 0.31 9.6 1.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 KLO15068.1 - 3.9 7.3 5.6 3.7 7.4 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator Het-C PF07217.11 KLO15069.1 - 4.3e-07 28.9 0.1 1e-06 27.6 0.1 1.6 1 1 1 2 2 2 1 Heterokaryon incompatibility protein Het-C PRD PF00874.20 KLO15069.1 - 0.013 15.8 0.1 0.045 14.0 0.0 2.0 2 1 0 2 2 2 0 PRD domain DnaJ PF00226.31 KLO15070.1 - 1.3e-09 38.0 0.0 3.8e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 KLO15070.1 - 0.028 14.5 0.1 0.12 12.6 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat OxoGdeHyase_C PF16870.5 KLO15070.1 - 0.035 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal DnaJ PF00226.31 KLO15071.1 - 6.6e-09 35.8 0.0 2e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Peptidase_S46 PF10459.9 KLO15071.1 - 1.1 7.9 25.2 1.5 7.4 25.2 1.2 1 0 0 1 1 1 0 Peptidase S46 Asp-B-Hydro_N PF05279.11 KLO15071.1 - 3.2 7.7 22.3 6.2 6.8 22.3 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Het-C PF07217.11 KLO15072.1 - 1.6e-208 693.8 0.1 4.3e-208 692.4 0.1 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C TPR_12 PF13424.6 KLO15072.1 - 0.081 13.2 0.1 0.29 11.5 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat ApbA_C PF08546.11 KLO15073.1 - 3.6e-30 104.7 0.0 5.2e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KLO15073.1 - 4.7e-15 55.6 0.0 8.3e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.21 KLO15074.1 - 2.6e-38 131.9 0.0 3.7e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family RNase_T PF00929.24 KLO15076.1 - 3.6e-09 37.4 0.1 5.3e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 Exonuclease LSM PF01423.22 KLO15082.1 - 9.9e-18 63.6 0.1 1.5e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 LSM domain tRNA-synt_2 PF00152.20 KLO15083.1 - 1.6e-88 296.9 0.0 2.1e-88 296.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KLO15083.1 - 5.1e-10 39.2 0.0 1.2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain TP_methylase PF00590.20 KLO15084.1 - 1.3e-21 77.6 0.1 2.1e-21 76.8 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Evr1_Alr PF04777.13 KLO15085.1 - 1.6e-25 89.4 0.3 2.3e-25 89.0 0.3 1.2 1 0 0 1 1 1 1 Erv1 / Alr family OCRE PF17780.1 KLO15085.1 - 0.027 14.5 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 OCRE domain Glyco_hydro_71 PF03659.14 KLO15086.1 - 5e-109 364.5 0.0 6.1e-109 364.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Dynamin_N PF00350.23 KLO15087.1 - 5.4e-07 29.8 0.0 1.9e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Dynamin family DUF2087 PF09860.9 KLO15089.1 - 0.018 15.2 0.2 0.088 13.0 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) Pantoate_transf PF02548.15 KLO15090.1 - 4.7e-110 367.0 0.2 5.4e-110 366.8 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KLO15090.1 - 7.5e-08 32.1 0.4 8.6e-07 28.7 0.0 2.2 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase Sulfate_transp PF00916.20 KLO15092.1 - 4.5e-84 282.4 18.3 4.5e-84 282.4 18.3 1.4 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KLO15092.1 - 8.4e-16 57.7 0.0 1.4e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KLO15092.1 - 0.00039 20.7 0.1 0.0029 17.9 0.0 2.3 2 0 0 2 2 2 1 STAS domain Phage_holin_3_1 PF05106.12 KLO15092.1 - 0.035 14.5 0.0 2.9 8.4 0.0 3.0 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) F-box-like PF12937.7 KLO15093.1 - 7.1e-09 35.4 0.0 1.6e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO15093.1 - 0.012 15.4 0.4 7.9 6.5 0.0 3.0 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 KLO15093.1 - 1.6 9.3 6.7 11 6.6 0.0 4.6 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO15094.1 - 3.7e-07 29.9 0.0 9.7e-07 28.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KLO15094.1 - 0.017 15.1 0.0 0.046 13.7 0.0 1.8 1 1 0 1 1 1 0 F-box-like domain DUF3254 PF11630.8 KLO15094.1 - 0.017 15.3 0.2 0.054 13.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) CENP-B_dimeris PF09026.10 KLO15097.1 - 0.7 10.3 6.3 1.4 9.3 0.2 3.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain zf-MYND PF01753.18 KLO15098.1 - 4.6e-07 29.8 16.4 1.1e-06 28.6 16.4 1.7 1 0 0 1 1 1 1 MYND finger PKS_DE PF18369.1 KLO15098.1 - 0.14 12.7 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain zf-Mss51 PF13824.6 KLO15098.1 - 0.27 11.4 6.2 0.63 10.2 6.2 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 BTB PF00651.31 KLO15099.1 - 5.7e-10 39.4 0.0 7.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Sulfate_transp PF00916.20 KLO15100.1 - 1.4e-75 254.5 21.2 1.8e-75 254.1 21.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KLO15100.1 - 1.5e-16 60.0 0.0 3.2e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KLO15100.1 - 0.082 13.3 0.3 0.32 11.4 0.3 2.1 1 1 0 1 1 1 0 STAS domain DUF4124 PF13511.6 KLO15100.1 - 0.2 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) GDE_C PF06202.14 KLO15101.1 - 0.00055 19.0 0.2 0.07 12.1 0.0 2.4 2 1 0 2 2 2 2 Amylo-alpha-1,6-glucosidase F-box-like PF12937.7 KLO15103.1 - 2.1e-07 30.7 0.1 4.9e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO15103.1 - 0.13 12.1 0.6 33 4.5 0.0 3.0 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 KLO15103.1 - 0.22 12.0 11.5 17 6.0 0.0 5.8 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO15105.1 - 2.4e-07 30.5 0.0 7.5e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO15106.1 - 1.9e-06 27.6 0.1 5.5e-06 26.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like DUF3254 PF11630.8 KLO15106.1 - 0.015 15.5 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) F-box PF00646.33 KLO15106.1 - 0.047 13.6 2.7 8.4 6.4 0.0 3.0 3 0 0 3 3 3 0 F-box domain Sigma70_ner PF04546.13 KLO15106.1 - 0.11 12.4 0.3 0.22 11.4 0.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region BTB PF00651.31 KLO15107.1 - 5.2e-07 29.9 0.0 1.4e-06 28.5 0.0 1.7 1 1 1 2 2 2 1 BTB/POZ domain RNA_pol_I_A49 PF06870.12 KLO15107.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor BTB PF00651.31 KLO15108.1 - 4.5e-05 23.6 0.0 7.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Mito_fiss_reg PF05308.11 KLO15108.1 - 0.21 11.7 4.7 0.37 10.8 4.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KLO15108.1 - 1.5 8.2 9.4 2.4 7.5 9.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CopD PF05425.13 KLO15109.1 - 0.0019 18.6 2.3 0.81 10.1 1.4 2.7 2 0 0 2 2 2 2 Copper resistance protein D TMEM18 PF14770.6 KLO15109.1 - 0.045 13.7 0.3 0.045 13.7 0.3 3.0 4 0 0 4 4 4 0 Transmembrane protein 18 DUF3704 PF12488.8 KLO15109.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) PHO4 PF01384.20 KLO15109.1 - 0.17 10.9 0.9 0.46 9.5 0.0 1.9 2 0 0 2 2 2 0 Phosphate transporter family DUF2263 PF10021.9 KLO15111.1 - 1.5e-39 135.7 0.0 2.2e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) PARG_cat PF05028.14 KLO15111.1 - 0.089 12.1 0.1 0.41 9.9 0.0 1.8 2 0 0 2 2 2 0 Poly (ADP-ribose) glycohydrolase (PARG) DUF2263 PF10021.9 KLO15112.1 - 4.5e-34 117.9 0.0 9.7e-34 116.8 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Glyco_hydro_28 PF00295.17 KLO15113.1 - 9.6e-62 208.9 9.4 1.3e-61 208.5 9.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 BTB PF00651.31 KLO15114.1 - 0.025 14.8 0.0 0.052 13.8 0.0 1.6 1 1 0 1 1 1 0 BTB/POZ domain ArsB PF02040.15 KLO15116.1 - 1e-06 28.4 4.3 1.8e-05 24.3 1.8 2.3 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 KLO15116.1 - 1.9e-05 24.0 14.4 9.5e-05 21.7 14.4 2.2 1 1 0 1 1 1 1 Citrate transporter DUF4342 PF14242.6 KLO15116.1 - 0.026 14.5 1.1 0.082 12.9 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Abhydrolase_3 PF07859.13 KLO15117.1 - 9.7e-23 81.1 0.5 3.4e-22 79.3 0.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO15117.1 - 2.5e-12 46.4 0.0 8.6e-12 44.6 0.0 2.0 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KLO15117.1 - 0.024 15.2 0.7 0.043 14.4 0.7 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family ArsB PF02040.15 KLO15118.1 - 3.3e-14 53.1 21.8 1.5e-12 47.6 6.9 2.4 3 0 0 3 3 3 2 Arsenical pump membrane protein DUF4342 PF14242.6 KLO15118.1 - 0.024 14.6 0.7 0.16 12.0 0.7 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) AMP-binding PF00501.28 KLO15119.1 - 4.7e-74 249.5 0.0 6e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KLO15119.1 - 8.2e-17 62.0 0.2 1.9e-16 60.8 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KLO15119.1 - 2e-08 34.0 1.0 2e-08 34.0 1.0 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus CCDC-167 PF15188.6 KLO15120.1 - 0.1 13.0 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 CC2-LZ PF16516.5 KLO15120.1 - 0.19 12.1 0.2 0.37 11.2 0.2 1.4 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ThrE PF06738.12 KLO15121.1 - 8e-39 133.4 0.9 8e-39 133.4 0.9 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KLO15121.1 - 0.00016 21.8 16.5 0.0037 17.4 4.6 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE BTB PF00651.31 KLO15122.1 - 5.4e-11 42.7 0.0 1.2e-10 41.5 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO15124.1 - 1.1e-07 32.0 0.0 2.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CAP_N PF01213.19 KLO15124.1 - 0.14 11.6 2.0 0.18 11.2 2.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal BTB PF00651.31 KLO15126.1 - 1.2e-06 28.7 0.0 0.016 15.4 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain HTH_AraC PF00165.23 KLO15126.1 - 0.15 12.2 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family polyprenyl_synt PF00348.17 KLO15127.1 - 4.5e-65 219.2 0.0 5.4e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase BTB PF00651.31 KLO15128.1 - 3.4e-06 27.3 0.0 8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO15129.1 - 8.4e-09 35.6 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF2028 PF09667.10 KLO15129.1 - 5.7 6.9 12.2 4.3 7.3 10.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2028) PSDC PF12588.8 KLO15130.1 - 1.9e-34 118.7 0.0 3.3e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KLO15130.1 - 8.3e-34 116.9 0.0 1.1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KLO15131.1 - 9.1e-38 129.8 0.0 1.2e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 KLO15131.1 - 2.2e-35 121.7 0.1 8.4e-34 116.5 0.0 2.2 2 0 0 2 2 2 1 Phophatidylserine decarboxylase PET117 PF15786.5 KLO15133.1 - 4.6e-24 84.5 1.5 6.1e-24 84.1 1.5 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Cytadhesin_P30 PF07271.11 KLO15133.1 - 0.24 10.9 0.3 0.26 10.8 0.3 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 Sugar_tr PF00083.24 KLO15135.1 - 1.6e-104 350.3 13.6 1.9e-104 350.1 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO15135.1 - 4.9e-26 91.5 48.3 1.4e-25 90.0 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KLO15135.1 - 0.00014 20.4 1.9 0.00014 20.4 1.9 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KLO15135.1 - 0.29 9.5 9.4 0.6 8.4 9.4 1.5 1 0 0 1 1 1 0 Transmembrane secretion effector OATP PF03137.20 KLO15135.1 - 2.3 6.4 5.4 1.7 6.8 0.3 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family polyprenyl_synt PF00348.17 KLO15136.1 - 6.7e-94 313.7 0.0 1e-93 313.1 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Phage_Treg PF04761.12 KLO15136.1 - 0.08 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator MPS2 PF17060.5 KLO15142.1 - 1.9e-05 24.1 0.2 2.6e-05 23.7 0.2 1.1 1 0 0 1 1 1 1 Monopolar spindle protein 2 PI3K_P85_iSH2 PF16454.5 KLO15143.1 - 0.0045 16.6 1.1 0.0045 16.6 1.1 2.3 3 0 0 3 3 3 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Mod_r PF07200.13 KLO15143.1 - 0.016 15.3 4.4 0.037 14.1 3.1 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein vATP-synt_AC39 PF01992.16 KLO15143.1 - 0.018 14.5 0.4 0.079 12.4 0.2 2.0 2 0 0 2 2 2 0 ATP synthase (C/AC39) subunit Csm1_N PF18504.1 KLO15143.1 - 0.052 13.9 1.2 0.15 12.4 1.2 1.8 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF4883 PF16224.5 KLO15143.1 - 0.13 12.5 0.0 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 DOmain of unknown function (DUF4883) RRM_1 PF00076.22 KLO15144.1 - 2.9e-30 103.9 0.6 6.9e-09 35.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 KLO15144.1 - 2.3e-05 24.3 0.0 1.1 9.2 0.0 4.0 3 1 1 4 4 4 2 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 KLO15144.1 - 0.00042 20.1 0.0 2.9 7.8 0.0 4.1 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KLO15144.1 - 0.00095 18.8 0.0 0.12 11.9 0.0 3.1 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KLO15144.1 - 0.0014 18.6 0.1 1.5 8.9 0.1 2.7 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 KLO15144.1 - 0.095 12.8 0.0 1.9 8.6 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif Nup35_RRM_2 PF14605.6 KLO15144.1 - 0.19 11.7 0.0 25 4.9 0.1 3.5 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif TFIIA PF03153.13 KLO15144.1 - 4.2 7.3 11.6 0.43 10.5 6.7 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ABC_tran PF00005.27 KLO15145.1 - 1.2e-30 106.8 0.0 2.3e-15 57.3 0.0 3.4 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KLO15145.1 - 8.4e-10 38.9 2.0 0.033 14.0 0.3 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KLO15145.1 - 9.5e-06 25.2 0.0 0.01 15.3 0.0 3.3 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KLO15145.1 - 2.6e-05 24.4 0.1 0.027 14.7 0.1 2.8 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KLO15145.1 - 0.002 17.8 0.0 0.026 14.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain Ploopntkinase1 PF18748.1 KLO15145.1 - 0.0047 16.5 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop Nucleotide Kinase1 DUF3584 PF12128.8 KLO15145.1 - 0.014 12.9 0.0 0.02 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NACHT PF05729.12 KLO15145.1 - 0.015 15.2 0.0 0.16 11.8 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_16 PF13191.6 KLO15145.1 - 0.071 13.5 0.2 1.7 9.0 0.1 2.6 2 2 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KLO15145.1 - 0.16 11.9 0.0 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF3759 PF12585.8 KLO15146.1 - 3.6e-25 87.8 7.8 5.4e-25 87.2 7.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Bromodomain PF00439.25 KLO15147.1 - 1.5e-21 76.2 1.9 4e-21 74.9 0.9 2.3 2 1 1 3 3 3 1 Bromodomain Bromo_TP PF07524.13 KLO15147.1 - 1.6e-07 31.2 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated WD40 PF00400.32 KLO15148.1 - 2.8e-19 69.1 18.1 0.00033 21.4 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO15148.1 - 5e-17 62.0 1.7 5e-06 26.7 0.1 4.3 4 0 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO15148.1 - 0.00011 22.2 0.3 0.051 13.4 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KLO15148.1 - 0.014 14.4 0.1 1.9 7.4 0.0 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KLO15148.1 - 0.046 13.0 0.1 2.5 7.3 0.0 2.6 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal MTCP1 PF08991.10 KLO15149.1 - 1.1e-21 76.8 8.5 1.2e-21 76.7 8.5 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KLO15149.1 - 0.0075 16.4 6.6 0.014 15.5 6.6 1.5 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KLO15149.1 - 0.066 13.2 1.1 0.066 13.2 1.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KLO15149.1 - 1.3 9.0 9.5 0.76 9.8 7.7 1.5 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cpn60_TCP1 PF00118.24 KLO15150.1 - 4e-148 494.1 6.0 4.5e-148 493.9 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LETM1 PF07766.13 KLO15150.1 - 0.013 14.8 0.0 0.067 12.5 0.0 1.9 1 1 0 1 1 1 0 LETM1-like protein Nitro_FeMo-Co PF02579.17 KLO15150.1 - 0.02 15.2 0.0 0.061 13.7 0.0 1.9 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Cerato-platanin PF07249.12 KLO15151.1 - 9.9e-36 122.5 0.2 1.2e-35 122.2 0.2 1.0 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.12 KLO15152.1 - 2.7e-18 66.2 0.1 3.4e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.12 KLO15153.1 - 1.5e-24 86.4 0.1 1.8e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.12 KLO15154.1 - 4.3e-19 68.8 0.1 6.6e-19 68.2 0.1 1.2 1 0 0 1 1 1 1 Cerato-platanin Hydrophobin PF01185.18 KLO15156.1 - 2.8e-22 79.1 10.1 3.6e-22 78.8 10.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin PRCC PF10253.9 KLO15156.1 - 0.026 15.3 1.7 0.029 15.2 1.7 1.0 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Mito_fiss_reg PF05308.11 KLO15156.1 - 0.14 12.2 12.0 0.19 11.8 12.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Retinal PF15449.6 KLO15156.1 - 3.9 5.1 21.4 4 5.1 21.4 1.0 1 0 0 1 1 1 0 Retinal protein DUF1700 PF08006.11 KLO15158.1 - 3.6 7.1 5.6 6 6.4 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Acetyltransf_7 PF13508.7 KLO15161.1 - 1.2e-06 28.9 0.1 1.9e-05 25.0 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO15161.1 - 6.2e-06 26.2 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO15161.1 - 4.6e-05 23.6 0.1 8.8e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family PanZ PF12568.8 KLO15161.1 - 0.082 12.6 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ MOZ_SAS PF01853.18 KLO15161.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family But2 PF09792.9 KLO15162.1 - 0.00099 19.5 0.0 0.0039 17.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.8 KLO15163.1 - 0.065 13.0 0.7 0.071 12.9 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KLO15164.1 - 2.3e-17 63.5 0.0 3.2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KLO15165.1 - 1.4e-16 61.0 0.5 1.9e-16 60.5 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TRAPPC10 PF12584.8 KLO15165.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 WSC PF01822.19 KLO15166.1 - 7.9e-38 128.5 38.4 4e-20 71.8 14.1 2.1 2 0 0 2 2 2 2 WSC domain Ferric_reduct PF01794.19 KLO15167.1 - 1.9e-18 66.8 11.7 1.9e-18 66.8 11.7 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KLO15167.1 - 3.3e-16 59.8 0.0 5.2e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KLO15167.1 - 3.4e-11 43.2 0.0 7.9e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain ArAE_2_N PF10337.9 KLO15167.1 - 0.00019 20.6 0.4 0.00033 19.8 0.4 1.3 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal NAD_binding_1 PF00175.21 KLO15167.1 - 0.0031 18.2 0.0 0.3 11.8 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain EPSP_synthase PF00275.20 KLO15168.1 - 9.4e-117 390.2 0.0 1.4e-116 389.6 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KLO15168.1 - 2.6e-101 338.2 0.0 5e-101 337.3 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KLO15168.1 - 1.7e-51 175.7 0.0 3e-51 174.9 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KLO15168.1 - 5.3e-33 114.4 0.0 4.4e-32 111.4 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KLO15168.1 - 1.4e-24 86.1 0.0 4.7e-24 84.4 0.0 2.0 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KLO15168.1 - 3.9e-08 33.3 0.0 9.2e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KLO15168.1 - 2.3e-07 30.4 0.0 5.8e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KLO15168.1 - 9.4e-05 22.5 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RTC PF01137.21 KLO15168.1 - 0.059 12.6 0.1 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA 3'-terminal phosphate cyclase Asparaginase_C PF17763.1 KLO15168.1 - 0.075 13.3 0.0 0.59 10.4 0.0 2.5 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain AAA_33 PF13671.6 KLO15168.1 - 0.15 12.3 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain LRR_6 PF13516.6 KLO15169.1 - 7.5e-14 50.5 12.3 0.011 15.7 0.6 8.1 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 KLO15169.1 - 8.4e-05 22.9 12.2 2.6 8.6 0.1 6.0 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KLO15169.1 - 0.017 15.6 16.3 9.9 7.2 0.0 7.3 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.6 KLO15169.1 - 0.94 9.3 24.2 8.5 6.2 0.2 7.3 5 2 2 7 7 7 0 Leucine rich repeat Abhydrolase_6 PF12697.7 KLO15170.1 - 8.3e-12 46.2 0.4 1.1e-11 45.7 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO15170.1 - 3.2e-08 33.1 0.2 7.3e-08 32.0 0.1 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KLO15170.1 - 4.7e-08 33.0 0.0 1.8e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Bestrophin PF01062.21 KLO15171.1 - 7.2e-33 114.2 0.6 2.9e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.21 KLO15172.1 - 1.9e-36 126.0 1.6 6.5e-24 84.8 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF3821 PF12863.7 KLO15172.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) DUF2304 PF10066.9 KLO15172.1 - 9.3 6.5 8.4 0.15 12.3 1.2 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Pyr_redox_2 PF07992.14 KLO15173.1 - 2e-51 175.0 0.1 2.6e-51 174.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO15173.1 - 2.6e-10 40.7 1.6 1.4e-09 38.4 0.1 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO15173.1 - 0.008 15.5 0.2 0.37 10.0 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO15173.1 - 0.015 14.0 3.4 0.052 12.2 0.0 2.8 1 1 2 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.6 KLO15173.1 - 0.11 12.9 0.6 2.4 8.7 0.0 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.24 KLO15173.1 - 0.55 9.7 4.2 6 6.3 2.3 2.5 1 1 1 2 2 2 0 FAD dependent oxidoreductase CUE PF02845.16 KLO15174.1 - 1.3e-11 43.9 0.0 2.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 KLO15174.1 - 0.028 14.5 0.3 0.069 13.2 0.3 1.6 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 AA_permease PF00324.21 KLO15175.1 - 3.4e-101 339.2 31.9 6.6e-56 189.9 14.1 1.9 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KLO15175.1 - 3.3e-26 92.1 32.1 5.8e-26 91.3 32.1 1.3 1 1 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.7 KLO15178.1 - 1.2e-10 42.4 0.2 1.6e-10 42.0 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO15178.1 - 6.3e-09 35.9 0.0 2.3e-08 34.0 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO15178.1 - 7.8e-07 28.6 0.1 2.3e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIP PF03583.14 KLO15178.1 - 0.035 13.4 0.4 1.1 8.6 0.1 2.1 2 0 0 2 2 2 0 Secretory lipase Pkinase_fungal PF17667.1 KLO15184.1 - 2e-39 135.5 0.0 3.6e-34 118.2 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase Plavaka PF18759.1 KLO15185.1 - 2.5e-68 230.7 0.5 3.2e-68 230.3 0.5 1.2 1 0 0 1 1 1 1 Plavaka transposase peroxidase PF00141.23 KLO15186.1 - 2.4e-21 76.5 0.0 1.1e-20 74.4 0.0 1.8 1 1 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KLO15186.1 - 1.1e-19 70.1 1.1 1.1e-19 70.1 1.1 2.0 2 0 0 2 2 2 1 Fungal peroxidase extension region L51_S25_CI-B8 PF05047.16 KLO15187.1 - 2e-14 53.2 0.0 2.6e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RGS PF00615.19 KLO15188.1 - 1.3e-10 41.5 4.6 3.4e-05 24.1 0.5 3.1 2 1 0 2 2 2 2 Regulator of G protein signaling domain Pex19 PF04614.12 KLO15189.1 - 1.9e-61 207.9 1.2 3.1e-61 207.3 0.7 1.4 2 0 0 2 2 2 1 Pex19 protein family SWI-SNF_Ssr4 PF08549.10 KLO15189.1 - 1.9 7.0 5.8 2.6 6.6 5.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Ndc1_Nup PF09531.10 KLO15190.1 - 2e-85 287.8 7.5 2.3e-85 287.6 7.5 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup PCRF PF03462.18 KLO15191.1 - 2.3e-51 174.5 0.2 9.8e-51 172.4 0.0 2.1 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KLO15191.1 - 1.1e-34 118.9 3.1 1.1e-34 118.9 3.1 1.8 2 0 0 2 2 2 1 RF-1 domain RSN1_7TM PF02714.15 KLO15192.1 - 1.7e-81 273.6 24.0 2.9e-81 272.8 24.0 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KLO15192.1 - 3.1e-35 121.3 0.6 3.1e-35 121.3 0.6 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KLO15192.1 - 3.5e-34 118.5 0.0 5.9e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 KLO15192.1 - 0.81 8.5 7.8 0.83 8.4 6.2 1.9 1 1 0 1 1 1 0 Calcium-activated chloride channel Zn_ribbon_17 PF17120.5 KLO15193.1 - 2.2e-09 36.8 15.2 2.2e-09 36.8 15.2 1.9 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KLO15193.1 - 0.018 15.9 0.3 0.018 15.9 0.3 4.6 6 0 0 6 6 6 0 WD domain, G-beta repeat CMAS PF02353.20 KLO15194.1 - 6.4e-67 225.7 0.2 7.7e-67 225.5 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KLO15194.1 - 5.3e-12 46.3 0.0 1.6e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO15194.1 - 1.5e-10 41.5 0.0 1e-09 38.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO15194.1 - 1.8e-09 37.6 0.0 3.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO15194.1 - 1.7e-05 25.5 0.0 3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO15194.1 - 0.00033 20.2 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KLO15194.1 - 0.00048 20.0 0.0 0.0019 18.0 0.0 1.8 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KLO15194.1 - 0.00082 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KLO15194.1 - 0.0024 17.4 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 PrmA PF06325.13 KLO15194.1 - 0.018 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KLO15194.1 - 0.051 13.6 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KLO15194.1 - 0.07 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.19 KLO15194.1 - 0.14 12.3 0.1 0.42 10.7 0.1 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Pkinase_Tyr PF07714.17 KLO15195.1 - 2.4e-33 115.5 0.0 2.7e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO15195.1 - 1.5e-27 96.7 0.0 1.7e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO15195.1 - 0.11 12.5 0.2 0.11 12.5 0.2 1.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Solute_trans_a PF03619.16 KLO15196.1 - 2.6e-56 191.1 1.5 1.8e-45 155.5 0.1 2.3 1 1 1 2 2 2 2 Organic solute transporter Ostalpha UQ_con PF00179.26 KLO15196.1 - 7.6e-39 132.6 0.0 1.3e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Complex1_LYR PF05347.15 KLO15196.1 - 0.085 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Frizzled PF01534.17 KLO15196.1 - 0.24 10.4 2.2 0.41 9.7 2.2 1.2 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region Nrap_D4 PF17405.2 KLO15197.1 - 2.2e-58 197.1 0.0 5.1e-58 195.9 0.0 1.6 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 KLO15197.1 - 5.1e-42 143.7 0.0 1e-41 142.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D5 PF17406.2 KLO15197.1 - 9.1e-39 132.8 0.0 2.5e-38 131.4 0.0 1.8 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D6 PF17407.2 KLO15197.1 - 7.7e-36 123.3 0.0 7.1e-35 120.2 0.0 2.3 2 0 0 2 2 2 1 Nrap protein domain 6 Nrap PF03813.14 KLO15197.1 - 2.8e-34 118.4 0.3 4.9e-34 117.6 0.3 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 KLO15197.1 - 2.6e-31 108.4 0.0 6.3e-31 107.2 0.0 1.7 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain LysM PF01476.20 KLO15198.1 - 1.8e-13 50.3 0.0 2.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 LysM domain adh_short PF00106.25 KLO15201.1 - 8.1e-38 129.8 0.2 1.7e-37 128.8 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO15201.1 - 2.3e-36 125.5 0.1 3.8e-22 79.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO15201.1 - 5.2e-09 36.3 0.3 1.8e-08 34.5 0.2 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KLO15201.1 - 0.19 11.2 0.4 0.34 10.3 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KLO15202.1 - 1e-38 132.8 0.0 2.2e-38 131.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO15202.1 - 3.1e-36 125.1 0.1 3.1e-34 118.5 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO15202.1 - 7.2e-08 32.6 0.3 2.3e-07 30.9 0.1 1.8 2 0 0 2 2 2 1 KR domain Oxidored_FMN PF00724.20 KLO15203.1 - 2.6e-93 313.0 0.0 3.1e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Gmx_para_CXXCG PF09535.10 KLO15203.1 - 0.17 11.2 0.0 0.53 9.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) EHN PF06441.12 KLO15204.1 - 6.5e-20 71.5 0.0 1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KLO15204.1 - 1.6e-06 28.0 0.1 2.6e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO15204.1 - 0.025 15.2 0.7 0.13 12.9 0.7 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family EHN PF06441.12 KLO15205.1 - 1.1e-16 61.1 0.0 1.7e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KLO15205.1 - 3.3e-07 30.2 0.1 4.8e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO15205.1 - 0.028 15.0 4.6 0.17 12.5 4.6 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pkinase_Tyr PF07714.17 KLO15208.1 - 3.9e-35 121.4 0.0 5.8e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO15208.1 - 2.7e-32 112.2 0.0 4.2e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO15208.1 - 0.084 12.8 0.1 0.2 11.5 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KLO15208.1 - 0.12 11.3 0.0 0.59 9.0 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain zf-PARP PF00645.18 KLO15210.1 - 1e-26 93.6 0.4 1.6e-26 93.0 0.4 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Tannase PF07519.11 KLO15211.1 - 3.1e-109 366.0 0.0 3.6e-109 365.8 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KLO15211.1 - 0.0049 16.2 0.0 0.083 12.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KLO15211.1 - 0.073 12.5 0.0 0.75 9.2 0.1 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Tannase PF07519.11 KLO15212.1 - 1e-106 357.7 0.0 1.2e-106 357.4 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KLO15212.1 - 0.00072 18.9 0.0 0.034 13.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KLO15212.1 - 0.019 14.7 0.1 0.059 13.0 0.1 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KLO15212.1 - 0.1 12.0 0.5 1.1 8.7 0.5 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 KLO15212.1 - 0.16 11.5 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Putative esterase QCR10 PF09796.9 KLO15213.1 - 0.013 15.5 4.5 0.54 10.3 0.2 2.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF4018 PF13210.6 KLO15213.1 - 0.092 12.5 0.9 0.15 11.9 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) Hemerythrin PF01814.23 KLO15214.1 - 1.3e-11 45.2 3.9 2.1e-11 44.6 3.9 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF3269 PF11673.8 KLO15214.1 - 0.045 14.1 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3269) Pkinase_Tyr PF07714.17 KLO15215.1 - 6e-33 114.2 0.0 2.3e-32 112.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO15215.1 - 1.6e-27 96.5 0.0 1.2e-26 93.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO15216.1 - 4.3e-37 127.8 0.0 1.3e-36 126.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO15216.1 - 4.4e-34 118.1 0.0 1.3e-33 116.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Zn_clus PF00172.18 KLO15216.1 - 3.9e-06 26.9 8.9 7.4e-06 26.0 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Haspin_kinase PF12330.8 KLO15216.1 - 0.014 14.3 0.1 0.033 13.1 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain PHD PF00628.29 KLO15217.1 - 4.8e-07 29.6 0.6 4.8e-07 29.6 0.6 4.1 5 0 0 5 5 5 1 PHD-finger Methyltransf_16 PF10294.9 KLO15218.1 - 5.9e-43 146.6 0.0 7.9e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KLO15218.1 - 0.032 13.6 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KLO15218.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 KLO15219.1 - 4.6e-67 226.7 0.0 2.6e-66 224.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 SSF PF00474.17 KLO15220.1 - 5.2e-21 75.0 29.8 5.2e-21 75.0 29.8 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2207 PF09972.9 KLO15220.1 - 0.018 13.8 0.0 0.018 13.8 0.0 4.1 3 2 1 4 4 4 0 Predicted membrane protein (DUF2207) YjeF_N PF03853.15 KLO15221.1 - 1.7e-36 125.6 0.0 2.1e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus HTH_34 PF13601.6 KLO15221.1 - 0.048 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain adh_short_C2 PF13561.6 KLO15222.1 - 1.8e-54 184.8 2.7 3.9e-54 183.7 2.7 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO15222.1 - 4.1e-49 166.7 1.0 6.7e-49 166.0 1.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO15222.1 - 3.2e-07 30.4 1.4 5.3e-07 29.7 1.4 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO15222.1 - 0.14 11.6 0.2 0.59 9.6 0.3 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Tannase PF07519.11 KLO15223.1 - 1.8e-101 340.3 0.0 2.2e-101 340.1 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KLO15223.1 - 5.4e-05 22.6 0.0 0.042 13.1 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Profilin PF00235.19 KLO15224.1 - 6.8e-43 146.0 0.2 7.5e-43 145.8 0.2 1.0 1 0 0 1 1 1 1 Profilin AAA PF00004.29 KLO15225.1 - 3e-21 76.2 0.0 5.1e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KLO15225.1 - 0.0022 18.0 0.1 0.011 15.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KLO15225.1 - 0.003 18.0 0.1 0.34 11.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 KLO15225.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.6 KLO15225.1 - 0.023 14.5 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KLO15225.1 - 0.036 14.3 0.1 0.73 10.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 KLO15225.1 - 0.082 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Guanylate_kin PF00625.21 KLO15225.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase Macro PF01661.21 KLO15226.1 - 4.1e-42 142.9 0.2 6.7e-42 142.3 0.2 1.3 1 0 0 1 1 1 1 Macro domain PS_Dcarbxylase PF02666.15 KLO15227.1 - 8.6e-61 205.0 0.0 1.5e-60 204.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KLO15227.1 - 1.2e-40 137.9 0.1 6.3e-20 71.4 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.6 KLO15227.1 - 5.2e-05 23.6 0.3 0.00016 22.1 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KLO15227.1 - 0.00051 19.8 0.0 0.034 14.1 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KLO15227.1 - 0.029 13.9 0.0 0.63 9.7 0.0 2.7 2 0 0 2 2 2 0 EF hand DUF4094 PF13334.6 KLO15228.1 - 1.5 9.3 5.4 5.7 7.4 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF1980 PF09323.10 KLO15228.1 - 1.6 8.6 4.3 2.6 7.9 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PARP PF00644.20 KLO15229.1 - 2.1e-15 56.9 5.9 2.5e-11 43.6 5.9 3.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.20 KLO15231.1 - 1.2e-17 64.2 2.4 1.3e-09 38.0 0.0 3.0 2 1 1 3 3 3 3 Poly(ADP-ribose) polymerase catalytic domain Lact_bio_phlase PF09508.10 KLO15231.1 - 0.12 10.8 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase N-terminal TIM barrel domain TcpS PF17456.2 KLO15231.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S DFRP_C PF16543.5 KLO15233.1 - 1.1e-31 109.2 3.6 1.1e-31 109.2 3.6 3.2 3 0 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KLO15233.1 - 1.4e-05 24.9 1.4 1.4e-05 24.9 1.4 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KLO15233.1 - 1.6e-05 24.7 4.9 1.6e-05 24.7 4.9 3.1 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 KLO15233.1 - 3.3e-05 23.6 12.9 0.00055 19.7 1.9 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 KLO15233.1 - 0.0073 17.0 12.2 0.011 16.5 2.3 3.7 2 1 1 3 3 3 1 Torus domain zf-CCCH_2 PF14608.6 KLO15233.1 - 0.038 14.5 3.2 0.038 14.5 3.2 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Tankyrase_bdg_C PF15327.6 KLO15233.1 - 0.062 13.8 0.4 0.062 13.8 0.4 2.6 2 1 1 3 3 3 0 Tankyrase binding protein C terminal domain zf-CCCH_3 PF15663.5 KLO15233.1 - 0.2 11.9 5.6 0.65 10.2 0.5 2.7 1 1 0 2 2 2 0 Zinc-finger containing family phage_tail_N PF08400.10 KLO15233.1 - 0.31 11.0 1.7 13 5.7 0.0 2.8 2 0 0 2 2 2 0 Prophage tail fibre N-terminal DUF4407 PF14362.6 KLO15233.1 - 2.1 7.6 6.5 1.7 8.0 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Torus PF16131.5 KLO15234.1 - 1.9e-39 134.8 2.9 3.6e-39 133.8 2.9 1.5 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 KLO15234.1 - 1.1e-05 25.2 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KLO15234.1 - 2.2e-05 24.3 0.0 4.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 KLO15234.1 - 0.067 13.3 5.3 0.13 12.3 5.3 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 KLO15234.1 - 0.49 10.4 6.8 0.87 9.6 6.8 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KLO15234.1 - 0.7 9.8 9.3 1.3 8.9 9.3 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger XRN1_D1 PF18332.1 KLO15235.1 - 1.4e-43 148.9 0.1 2.5e-43 148.1 0.1 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KLO15235.1 - 1.7e-31 108.2 0.3 4.4e-31 106.9 0.2 1.8 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KLO15235.1 - 2.4e-23 82.0 0.3 5.5e-23 80.9 0.3 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KLO15235.1 - 5.4e-05 23.2 0.2 0.00011 22.2 0.2 1.5 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 XRN_M PF17846.1 KLO15236.1 - 1.2e-57 195.9 9.9 1.4e-56 192.4 9.9 1.9 1 1 0 1 1 1 1 Xrn1 helical domain XRN1_D1 PF18332.1 KLO15236.1 - 0.077 12.8 0.2 0.077 12.8 0.2 1.6 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D1 domain Mito_carr PF00153.27 KLO15237.1 - 4.5e-55 183.6 3.9 1.5e-19 69.7 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KLO15237.1 - 0.06 12.5 0.0 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Coq4 PF05019.13 KLO15239.1 - 3.8e-102 340.3 0.0 4.5e-102 340.1 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Glyco_hydro_79C PF16862.5 KLO15240.1 - 5.2e-13 49.8 0.6 9.9e-13 48.9 0.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain BAR_3 PF16746.5 KLO15242.1 - 8.7e-05 22.3 5.0 0.00016 21.5 5.0 1.3 1 0 0 1 1 1 1 BAR domain of APPL family Rubrerythrin PF02915.17 KLO15242.1 - 0.0099 16.3 4.9 0.0099 16.3 4.9 2.1 2 0 0 2 2 2 1 Rubrerythrin BolA PF01722.18 KLO15243.1 - 3.7e-14 52.7 0.1 4.5e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 BolA-like protein DUF1882 PF08966.11 KLO15243.1 - 0.034 14.4 0.7 0.05 13.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) GMP_synt_C PF00958.22 KLO15244.1 - 1.6e-45 153.0 0.1 3.2e-45 152.1 0.1 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KLO15244.1 - 2.4e-37 128.6 0.0 4.4e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 KLO15244.1 - 3.3e-10 39.5 0.1 8.8e-05 21.7 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KLO15244.1 - 5.3e-10 39.4 0.0 1.3e-09 38.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 KLO15244.1 - 0.0043 15.9 0.1 0.0077 15.1 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 KLO15244.1 - 0.01 15.3 0.3 0.13 11.8 0.0 2.4 3 0 0 3 3 3 0 Queuosine biosynthesis protein QueC ThiI PF02568.14 KLO15244.1 - 0.037 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 KLO15244.1 - 0.22 11.3 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 PP-loop family tRNA-synt_1g PF09334.11 KLO15245.1 - 9.9e-134 446.0 0.0 1.2e-133 445.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 KLO15245.1 - 2.3e-09 37.2 7.7 7e-09 35.7 7.7 1.9 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 KLO15245.1 - 8.6e-05 21.0 0.0 0.00022 19.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) zinc-ribbons_6 PF07191.12 KLO15245.1 - 0.073 13.1 2.2 0.17 11.9 2.2 1.6 1 0 0 1 1 1 0 zinc-ribbons Anticodon_1 PF08264.13 KLO15245.1 - 0.088 12.8 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 Anticodon-binding domain of tRNA DZR PF12773.7 KLO15245.1 - 0.32 11.0 7.0 0.66 10.0 6.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon Sigma70_ner PF04546.13 KLO15245.1 - 0.44 10.4 7.5 0.71 9.7 4.7 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region HypA PF01155.19 KLO15245.1 - 1.8 8.6 3.9 4.2 7.4 3.1 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SARAF PF06682.12 KLO15246.1 - 2.6e-59 201.6 4.2 9.5e-59 199.7 4.2 1.7 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF2615 PF11027.8 KLO15246.1 - 0.034 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Chordopox_A13L PF05961.11 KLO15246.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein OPT PF03169.15 KLO15247.1 - 1.2e-143 480.0 14.5 1.4e-143 479.8 14.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_3_3 PF16083.5 KLO15247.1 - 0.047 13.8 9.5 0.62 10.2 0.3 4.8 3 1 0 3 3 3 0 LydA holin phage, holin superfamily III DUF3995 PF13160.6 KLO15247.1 - 0.048 14.0 0.1 0.048 14.0 0.1 3.7 3 2 0 3 3 3 0 Protein of unknown function (DUF3995) Zn_clus PF00172.18 KLO15248.1 - 2.7e-08 33.8 5.5 3.6e-08 33.4 5.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC73_C PF05179.14 KLO15250.1 - 2.3e-53 180.1 1.0 3.7e-53 179.4 1.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal MFS_1 PF07690.16 KLO15251.1 - 2.3e-20 72.8 33.4 3.7e-17 62.3 23.4 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KLO15251.1 - 3e-06 25.8 0.4 1.8e-05 23.3 0.3 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family SpoIIM PF01944.17 KLO15251.1 - 0.018 15.1 12.2 0.18 11.9 5.6 3.8 3 1 0 3 3 3 0 Stage II sporulation protein M Amidohydro_2 PF04909.14 KLO15252.1 - 1.5e-21 77.4 0.0 2.1e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase YchF-GTPase_C PF06071.13 KLO15253.1 - 2.1e-35 120.7 0.0 7.4e-35 119.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KLO15253.1 - 1.9e-18 66.6 0.0 1.3e-17 63.9 0.0 2.0 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KLO15253.1 - 7.3e-06 25.6 0.0 3e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KLO15253.1 - 0.036 13.1 0.1 0.088 11.8 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Shisa PF13908.6 KLO15254.1 - 0.4 10.9 1.6 0.56 10.4 1.6 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator F-box-like PF12937.7 KLO15256.1 - 5.8e-07 29.3 0.1 1.2e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO15256.1 - 0.037 13.9 0.6 0.037 13.9 0.6 2.3 2 0 0 2 2 2 0 F-box domain Glyco_hydro_18 PF00704.28 KLO15256.1 - 0.094 12.4 0.1 0.19 11.4 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 18 IBR PF01485.21 KLO15258.1 - 2.4e-07 30.9 35.6 6.3e-07 29.5 6.8 3.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain Sugar_tr PF00083.24 KLO15259.1 - 3.1e-118 395.5 24.9 4.1e-118 395.1 24.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO15259.1 - 6.8e-26 91.0 51.0 1.1e-18 67.3 19.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KLO15260.1 - 1.6e-69 234.8 0.0 2e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 KLO15261.1 - 2.9e-07 31.0 0.0 4.3e-05 24.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KLO15261.1 - 0.0021 18.4 0.0 7.8 7.4 0.0 3.8 3 1 1 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KLO15261.1 - 0.0085 16.7 0.0 6.2 7.5 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KLO15261.1 - 0.07 13.5 0.1 11 6.4 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) zf-MYND PF01753.18 KLO15262.1 - 1.4e-10 41.1 7.3 3.8e-10 39.7 7.3 1.8 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KLO15262.1 - 0.032 14.5 5.8 0.085 13.2 5.8 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 KLO15262.1 - 0.33 8.8 1.7 0.43 8.4 1.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Peptidase_C14 PF00656.22 KLO15264.1 - 6.3e-66 222.8 0.0 8.2e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KLO15264.1 - 0.0042 17.0 0.4 0.029 14.3 0.0 2.3 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain Metallophos PF00149.28 KLO15265.1 - 1.3e-11 45.4 0.0 2.7e-11 44.3 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KLO15265.1 - 4.8e-07 30.1 0.0 7.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KLO15265.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DUF3072 PF11272.8 KLO15265.1 - 4.5 7.2 4.6 54 3.8 0.2 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3072) eIF-1a PF01176.19 KLO15266.1 - 2.5e-20 72.0 0.3 3.5e-20 71.6 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Cellulase PF00150.18 KLO15267.1 - 3.1e-42 144.9 0.0 3.8e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_18 PF00704.28 KLO15268.1 - 2.3e-24 86.7 1.7 5.5e-24 85.5 1.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CobD_Cbib PF03186.13 KLO15268.1 - 0.091 12.0 0.2 0.2 10.8 0.1 1.5 2 0 0 2 2 2 0 CobD/Cbib protein Sugar_tr PF00083.24 KLO15269.1 - 1.3e-107 360.5 22.0 1.5e-107 360.3 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO15269.1 - 2.8e-33 115.3 51.7 1.7e-28 99.6 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Histone PF00125.24 KLO15271.1 - 2.8e-19 69.8 0.1 3.6e-19 69.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KLO15271.1 - 3.7e-10 39.4 0.0 7e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KLO15271.1 - 0.0019 18.4 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LRR_8 PF13855.6 KLO15274.1 - 2.5e-05 23.9 5.3 0.00029 20.5 0.4 3.9 3 1 0 3 3 3 1 Leucine rich repeat F-box-like PF12937.7 KLO15274.1 - 2.7e-05 24.0 0.1 6.7e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO15274.1 - 0.0087 16.5 7.9 5.5 7.6 0.2 5.9 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.33 KLO15274.1 - 0.032 14.1 0.3 0.13 12.1 0.3 2.2 1 0 0 1 1 1 0 F-box domain SH3_9 PF14604.6 KLO15275.1 - 0.055 13.3 0.0 0.32 10.9 0.0 2.2 2 1 0 2 2 2 0 Variant SH3 domain Pam17 PF08566.10 KLO15275.1 - 0.07 13.0 0.1 0.9 9.4 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Gram_pos_anchor PF00746.21 KLO15275.1 - 0.078 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif SKG6 PF08693.10 KLO15275.1 - 0.16 11.4 2.4 0.43 10.0 2.4 1.8 1 1 0 1 1 1 0 Transmembrane alpha-helix domain TMCCDC2 PF15844.5 KLO15276.1 - 0.012 15.6 1.1 0.088 12.7 0.1 2.3 1 1 1 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 Rab5ip PF07019.12 KLO15277.1 - 4.4 8.0 9.7 4.4 8.0 0.6 3.6 3 0 0 3 3 3 0 Rab5-interacting protein (Rab5ip) Trp_oprn_chp PF09534.10 KLO15278.1 - 0.0095 15.8 0.3 0.021 14.6 0.3 1.5 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LapA_dom PF06305.11 KLO15278.1 - 0.022 14.6 0.9 0.046 13.6 0.9 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Trs65 PF12735.7 KLO15278.1 - 0.031 13.7 4.3 0.065 12.6 4.3 1.5 1 1 0 1 1 1 0 TRAPP trafficking subunit Trs65 SSP160 PF06933.11 KLO15278.1 - 0.82 7.8 12.3 0.031 12.5 6.7 1.5 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 TFIIF_beta PF02270.15 KLO15281.1 - 1.4e-24 86.0 0.1 2.5e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KLO15281.1 - 1.2e-19 71.3 0.7 1.8e-18 67.5 0.7 2.4 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 KLO15281.1 - 0.068 14.0 0.4 0.16 12.8 0.2 1.6 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain GCIP PF13324.6 KLO15281.1 - 1.4 8.5 0.0 1.4 8.5 0.0 2.5 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting GATA PF00320.27 KLO15284.1 - 8.4e-16 57.3 5.4 8.4e-16 57.3 5.4 1.7 2 0 0 2 2 2 1 GATA zinc finger TFIIA PF03153.13 KLO15284.1 - 0.033 14.2 20.1 0.037 14.0 20.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM132D_C PF15706.5 KLO15285.1 - 0.024 14.4 0.6 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term IDO PF01231.18 KLO15286.1 - 3.8e-129 431.3 0.0 4.3e-129 431.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Cytochrom_C PF00034.21 KLO15287.1 - 1.3e-10 42.3 0.0 1.8e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KLO15287.1 - 3.6e-08 33.6 1.8 3.7e-07 30.4 1.8 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KLO15287.1 - 7.3e-06 25.7 0.2 3.5e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 KLO15287.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 CCP_MauG PF03150.14 KLO15287.1 - 0.13 12.9 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase ABC_membrane PF00664.23 KLO15289.1 - 1.7e-51 175.5 34.0 2.8e-28 99.3 15.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KLO15289.1 - 2.3e-50 170.7 0.0 4.9e-27 95.1 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KLO15289.1 - 4.9e-06 26.1 1.3 0.012 15.0 0.3 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KLO15289.1 - 2.9e-05 24.0 5.8 0.37 10.6 0.2 3.8 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KLO15289.1 - 7.7e-05 22.8 4.7 0.08 13.0 0.2 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO15289.1 - 0.00022 21.2 0.5 0.23 11.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KLO15289.1 - 0.00031 21.2 0.1 0.36 11.2 0.0 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KLO15289.1 - 0.002 17.8 2.9 1.2 8.9 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain Roc PF08477.13 KLO15289.1 - 0.027 14.7 0.5 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KLO15289.1 - 0.034 13.7 0.9 2 7.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KLO15289.1 - 0.042 13.4 0.2 1.9 8.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KLO15289.1 - 0.048 13.6 2.0 7.5 6.5 0.1 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 KLO15289.1 - 0.089 12.9 6.0 5.6 7.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 KLO15289.1 - 0.099 13.1 5.3 4.6 7.7 0.1 3.2 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.6 KLO15289.1 - 0.12 12.1 0.5 20 4.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KLO15289.1 - 0.16 11.7 1.2 0.37 10.5 0.2 2.2 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KLO15289.1 - 0.18 11.9 6.9 1.6 8.7 0.5 3.0 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 KLO15289.1 - 0.31 10.8 1.5 24 4.6 0.2 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 KLO15289.1 - 0.49 9.3 7.7 3 6.7 0.4 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KLO15289.1 - 0.67 9.5 3.1 2 8.0 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KLO15289.1 - 8.3 6.4 5.6 1.4 9.0 0.9 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain F-box-like PF12937.7 KLO15290.1 - 5.6e-07 29.4 0.1 1.8e-06 27.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO15290.1 - 7.9e-05 22.4 6.1 0.00016 21.4 0.0 3.3 3 0 0 3 3 3 1 F-box domain PG_binding_2 PF08823.11 KLO15290.1 - 0.18 12.1 1.4 11 6.5 0.1 3.1 3 0 0 3 3 3 0 Putative peptidoglycan binding domain F-box PF00646.33 KLO15291.1 - 1.2e-05 25.1 0.0 4.7e-05 23.2 0.0 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO15291.1 - 0.0012 18.7 0.0 0.0039 17.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KLO15291.1 - 0.0076 16.1 0.5 0.025 14.5 0.0 2.1 2 1 1 3 3 3 1 F-box F-box PF00646.33 KLO15292.1 - 8e-06 25.6 1.4 1.2e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KLO15292.1 - 4.6e-05 23.2 0.0 9.3e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like Noc2 PF03715.13 KLO15292.1 - 0.0027 17.0 0.2 0.004 16.4 0.2 1.2 1 0 0 1 1 1 1 Noc2p family F-box_4 PF15966.5 KLO15292.1 - 0.088 12.7 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 F-box Baculo_11_kDa PF06143.11 KLO15293.1 - 0.014 14.9 0.7 0.064 12.8 0.1 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family Moricin PF06451.11 KLO15294.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Moricin ABC2_membrane PF01061.24 KLO15298.1 - 6.4e-39 133.5 11.9 6.4e-39 133.5 11.9 2.2 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KLO15298.1 - 3e-26 92.6 0.1 9.5e-26 90.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 KLO15298.1 - 7.8e-06 25.2 23.2 7.8e-06 25.2 23.2 2.5 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 KLO15298.1 - 0.00078 19.3 0.1 0.97 9.2 0.1 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KLO15298.1 - 0.0083 16.0 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KLO15298.1 - 0.014 15.8 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KLO15298.1 - 0.017 15.7 0.1 0.029 14.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KLO15298.1 - 0.018 14.8 0.0 0.049 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KLO15298.1 - 0.034 14.6 0.0 0.084 13.3 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KLO15298.1 - 0.034 14.4 0.1 0.058 13.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KLO15298.1 - 0.041 13.8 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KLO15298.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KLO15298.1 - 0.074 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KLO15298.1 - 0.1 12.3 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Cytidylate kinase Rad17 PF03215.15 KLO15298.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_17 PF13207.6 KLO15298.1 - 0.14 12.6 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KLO15298.1 - 0.17 11.4 0.0 0.47 10.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KLO15298.1 - 0.19 12.2 0.0 0.34 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ILVD_EDD PF00920.21 KLO15299.1 - 4.9e-165 550.1 0.0 5.5e-165 549.9 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Ubiquitin_2 PF14560.6 KLO15301.1 - 0.058 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain LtrA PF06772.11 KLO15302.1 - 0.0091 15.3 1.0 0.011 15.0 1.0 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Cyt_c_ox_IV PF12270.8 KLO15302.1 - 0.087 13.0 0.3 0.14 12.3 0.3 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase subunit IV VCBS PF13517.6 KLO15303.1 - 1.7e-24 86.1 24.0 4.3e-10 40.0 3.4 5.8 3 2 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KLO15303.1 - 1.1e-07 31.8 22.8 0.27 11.4 0.1 6.5 6 0 0 6 6 6 5 FG-GAP repeat TcdB_toxin_midN PF12256.8 KLO15303.1 - 0.014 14.8 4.1 16 4.8 0.0 4.9 5 1 0 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region GTP1_OBG PF01018.22 KLO15303.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 GTP1/OBG PQQ_2 PF13360.6 KLO15305.1 - 0.035 13.7 0.0 1.4 8.5 0.0 2.1 1 1 0 2 2 2 0 PQQ-like domain CPSF_A PF03178.15 KLO15305.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.6 1 1 0 1 1 1 0 CPSF A subunit region Glyoxalase_3 PF13468.6 KLO15306.1 - 7.3e-28 97.9 0.1 1.8e-27 96.6 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain F-box-like PF12937.7 KLO15308.1 - 1.9e-05 24.4 0.1 7.2e-05 22.6 0.1 2.1 1 1 0 1 1 1 1 F-box-like DUF587 PF04532.12 KLO15308.1 - 0.11 11.8 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF587) F-box-like PF12937.7 KLO15309.1 - 0.00011 22.0 0.1 0.00032 20.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like AA_permease_2 PF13520.6 KLO15311.1 - 0.09 11.6 0.2 0.39 9.5 0.0 1.8 2 0 0 2 2 2 0 Amino acid permease CD34_antigen PF06365.12 KLO15311.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Peptidase_S10 PF00450.22 KLO15312.1 - 4.5e-185 616.0 2.1 1.6e-97 327.6 0.2 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase Pox_A9 PF04835.12 KLO15312.1 - 0.16 12.1 0.0 27 5.0 0.0 2.5 2 0 0 2 2 2 0 A9 protein conserved region Ras PF00071.22 KLO15313.1 - 7.9e-46 155.6 0.0 9.5e-46 155.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO15313.1 - 3.7e-21 75.6 0.0 5.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO15313.1 - 4.9e-09 35.9 0.0 7.5e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KLO15313.1 - 0.00016 21.3 0.0 0.00077 19.0 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KLO15313.1 - 0.0041 17.2 0.0 0.0073 16.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KLO15313.1 - 0.047 14.1 0.0 0.054 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KLO15313.1 - 0.12 11.9 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region MCM PF00493.23 KLO15313.1 - 0.2 10.7 0.0 0.37 9.9 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain DUF1691 PF07950.11 KLO15314.1 - 4e-05 24.3 1.4 0.00012 22.7 0.2 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1691) RWP-RK PF02042.15 KLO15314.1 - 0.058 13.4 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 RWP-RK domain Spt5-NGN PF03439.13 KLO15316.1 - 5.8e-12 45.3 0.0 1.2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KLO15316.1 - 5.7e-11 42.0 19.7 0.00068 19.5 1.4 5.3 5 0 0 5 5 5 3 KOW motif DUF4438 PF14505.6 KLO15316.1 - 0.0038 16.3 2.9 0.038 13.0 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4438) DUF3912 PF13051.6 KLO15316.1 - 0.056 13.7 0.3 2.9 8.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) SH3_15 PF18346.1 KLO15316.1 - 0.11 12.8 0.0 3.6 8.0 0.0 3.2 2 1 0 2 2 2 0 Mind bomb SH3 repeat domain E1-E2_ATPase PF00122.20 KLO15317.1 - 2.8e-46 157.3 11.1 1.9e-45 154.6 3.4 3.2 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 KLO15317.1 - 7.8e-23 81.9 0.0 4.1e-14 53.4 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KLO15317.1 - 7.4e-22 77.9 22.0 2.2e-17 63.3 2.3 3.7 3 1 0 3 3 3 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KLO15317.1 - 1.6e-19 69.8 0.0 3.2e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KLO15317.1 - 1.8e-13 49.9 0.0 4.1e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KLO15317.1 - 0.00013 21.8 0.7 0.041 13.6 0.5 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase OPT PF03169.15 KLO15319.1 - 7.1e-190 632.7 52.5 8.4e-190 632.5 52.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SeqA_N PF17206.3 KLO15319.1 - 0.2 11.0 0.9 4.1 6.8 0.1 2.7 2 0 0 2 2 2 0 SeqA protein N-terminal domain HMG_box PF00505.19 KLO15320.1 - 2.5e-13 50.2 6.6 5.9e-13 49.0 6.6 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO15320.1 - 1.6e-10 41.4 1.5 1.8e-10 41.3 1.5 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 KLO15320.1 - 0.14 12.1 3.1 0.18 11.8 3.1 1.4 1 1 0 1 1 1 0 HMG (high mobility group) box 5 Peptidase_S10 PF00450.22 KLO15321.1 - 4.6e-106 355.7 0.1 5.7e-106 355.4 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Thioredoxin_10 PF17991.1 KLO15322.1 - 0.062 13.8 0.0 0.12 12.9 0.0 1.4 2 0 0 2 2 2 0 Thioredoxin like C-terminal domain F-box-like PF12937.7 KLO15323.1 - 3.1e-05 23.8 0.2 8.8e-05 22.3 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO15325.1 - 0.00015 21.6 1.1 0.00037 20.3 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO15325.1 - 0.15 12.0 1.7 0.38 10.7 0.1 2.5 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO15326.1 - 1.3e-06 28.2 1.1 3.7e-06 26.7 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO15327.1 - 9.2e-08 31.9 3.9 1.2e-07 31.5 0.2 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO15327.1 - 0.17 11.8 1.9 0.25 11.3 0.1 2.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO15328.1 - 4e-08 33.0 1.6 1e-07 31.7 0.5 2.3 2 0 0 2 2 2 1 F-box-like DUF1148 PF06618.11 KLO15328.1 - 0.0069 16.5 0.3 0.016 15.3 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1148) F-box PF00646.33 KLO15328.1 - 0.054 13.4 0.6 0.054 13.4 0.6 2.2 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO15329.1 - 2.2e-09 37.1 2.0 8.1e-09 35.2 0.4 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO15329.1 - 0.004 17.0 0.9 0.004 17.0 0.9 3.0 3 0 0 3 3 3 1 F-box domain CaATP_NAI PF12515.8 KLO15329.1 - 0.3 10.7 2.1 15 5.3 0.2 2.5 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain LRR_8 PF13855.6 KLO15329.1 - 1.2 9.0 5.9 6.3 6.6 0.0 3.7 3 1 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.7 KLO15330.1 - 8.4e-10 38.4 2.9 4.1e-09 36.2 0.6 3.0 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KLO15330.1 - 0.013 15.9 6.8 8.1 7.0 0.1 4.8 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KLO15330.1 - 0.02 14.8 1.5 0.02 14.8 1.5 2.1 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.6 KLO15330.1 - 0.5 10.2 5.7 37 4.2 0.0 4.0 3 1 1 4 4 4 0 Leucine rich repeat F-box-like PF12937.7 KLO15333.1 - 1.2e-06 28.3 0.0 3.2e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO15333.1 - 0.34 11.4 0.1 0.34 11.4 0.1 2.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) FPN1 PF06963.12 KLO15334.1 - 7.4e-117 390.6 17.1 8.7e-117 390.3 17.1 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) F-box-like PF12937.7 KLO15335.1 - 2.2e-08 33.9 0.0 6.8e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO15335.1 - 0.00094 19.5 1.6 0.64 10.5 0.2 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO15336.1 - 3.8e-08 33.1 0.3 7.7e-08 32.1 0.3 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO15336.1 - 0.0022 18.4 0.7 0.41 11.2 0.0 3.9 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) COG5 PF10392.9 KLO15336.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 F-box-like PF12937.7 KLO15337.1 - 4.7e-08 32.8 0.5 1.2e-07 31.5 0.5 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO15337.1 - 4.8 7.2 7.0 2.7 8.0 1.5 3.2 3 1 0 3 3 3 0 F-box domain Ras PF00071.22 KLO15338.1 - 5.1e-53 179.0 0.0 5.8e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO15338.1 - 1.2e-19 70.7 0.0 1.7e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO15338.1 - 2.5e-07 30.3 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KLO15338.1 - 0.0024 17.4 0.0 0.011 15.2 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain F-box-like PF12937.7 KLO15339.1 - 9.2e-10 38.3 3.2 2.3e-09 37.0 3.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO15339.1 - 0.00038 20.3 2.4 0.0011 18.8 1.6 2.3 2 0 0 2 2 2 1 F-box domain DMT_6 PF04342.12 KLO15339.1 - 0.2 11.9 0.8 0.38 11.0 0.8 1.4 1 0 0 1 1 1 0 Putative member of DMT superfamily (DUF486) Ras PF00071.22 KLO15340.1 - 5.1e-58 195.2 0.2 7e-58 194.8 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO15340.1 - 1.5e-30 105.8 0.6 2.8e-30 105.0 0.2 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO15340.1 - 1.2e-09 37.8 0.0 1.7e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KLO15340.1 - 0.0025 17.4 0.1 0.0041 16.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KLO15340.1 - 0.0066 16.5 0.3 0.022 14.8 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO15340.1 - 0.019 14.9 0.8 3.2 7.6 0.1 2.4 2 1 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 KLO15340.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_32 PF13654.6 KLO15340.1 - 0.029 13.2 0.0 0.079 11.7 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KLO15340.1 - 0.06 13.6 0.1 0.31 11.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KLO15340.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin DUF4265 PF14085.6 KLO15340.1 - 0.12 12.3 0.0 6.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) AAA_16 PF13191.6 KLO15340.1 - 0.13 12.6 0.1 0.22 11.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain p450 PF00067.22 KLO15341.1 - 3.5e-56 190.9 0.0 9.9e-56 189.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Coa1 PF08695.10 KLO15341.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Zn_clus PF00172.18 KLO15342.1 - 1.2e-08 34.9 13.2 2.1e-08 34.2 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KLO15342.1 - 2.3e-05 23.6 4.7 4.4e-05 22.6 0.3 2.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain GH101_N PF17995.1 KLO15344.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase N-terminal ADK PF00406.22 KLO15345.1 - 1.3e-60 203.8 0.0 1.7e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KLO15345.1 - 4.2e-22 79.0 0.4 9.5e-22 77.9 0.1 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KLO15345.1 - 4e-17 61.9 0.2 2.1e-16 59.6 0.0 2.3 3 0 0 3 3 3 1 Adenylate kinase, active site lid AAA_33 PF13671.6 KLO15345.1 - 0.0016 18.6 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KLO15345.1 - 0.038 14.5 0.0 0.079 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain CMD PF02627.20 KLO15346.1 - 0.04 14.0 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family DDOST_48kD PF03345.14 KLO15347.1 - 4.3e-125 417.8 0.0 5.1e-125 417.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta F-box-like PF12937.7 KLO15348.1 - 2.4e-08 33.8 0.0 7.8e-08 32.1 0.0 1.9 1 1 0 1 1 1 1 F-box-like Guanylate_cyc_2 PF09778.9 KLO15349.1 - 0.26 10.6 0.0 0.4 10.0 0.0 1.3 1 0 0 1 1 1 0 Guanylylate cyclase F-box-like PF12937.7 KLO15351.1 - 1.1e-08 34.8 1.4 5.6e-08 32.5 0.1 2.9 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KLO15351.1 - 0.03 14.8 3.3 14 6.3 2.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KLO15351.1 - 0.064 13.1 0.1 0.25 11.3 0.1 2.1 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO15353.1 - 1.3e-08 34.6 0.6 6e-08 32.5 0.3 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO15353.1 - 0.19 12.2 4.2 3 8.4 0.0 4.4 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_11 PF18831.1 KLO15356.1 - 0.016 14.8 0.5 0.033 13.8 0.5 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.6 KLO15356.1 - 0.058 13.2 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Leucine rich repeat DUF4837 PF16125.5 KLO15359.1 - 0.02 13.9 0.1 0.022 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) BAR PF03114.18 KLO15360.1 - 3.8e-48 164.2 7.3 4.7e-48 163.9 7.3 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 KLO15360.1 - 0.0012 18.5 8.6 0.01 15.4 8.6 2.0 1 1 0 1 1 1 1 Arfaptin-like domain AAA_13 PF13166.6 KLO15360.1 - 0.0068 15.1 2.7 0.013 14.1 2.8 1.5 1 1 1 2 2 2 2 AAA domain Phage_TAC_10 PF10963.8 KLO15360.1 - 0.029 14.5 0.0 0.097 12.9 0.0 1.9 1 0 0 1 1 1 0 Phage tail assembly chaperone GldM_N PF12081.8 KLO15360.1 - 0.3 11.1 5.1 0.39 10.8 1.0 2.2 2 0 0 2 2 2 0 GldM N-terminal domain Sulfotransfer_3 PF13469.6 KLO15360.1 - 0.56 10.5 3.1 2.3 8.5 3.0 2.1 1 1 0 1 1 1 0 Sulfotransferase family FAM76 PF16046.5 KLO15360.1 - 0.95 8.8 6.7 3.2 7.0 6.7 1.7 1 1 0 1 1 1 0 FAM76 protein HAUS-augmin3 PF14932.6 KLO15360.1 - 1.1 8.8 6.8 0.43 10.1 0.7 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 zf-C4H2 PF10146.9 KLO15360.1 - 1.2 9.5 5.1 5.2 7.3 5.1 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein TMPIT PF07851.13 KLO15360.1 - 1.3 8.2 4.1 6.5 5.9 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein Clathrin_lg_ch PF01086.17 KLO15362.1 - 3.8e-48 164.5 0.2 5.4e-48 164.0 0.2 1.2 1 0 0 1 1 1 1 Clathrin light chain YbbR PF07949.12 KLO15362.1 - 0.16 12.3 0.2 22 5.5 0.1 2.4 2 0 0 2 2 2 0 YbbR-like protein NUDIX PF00293.28 KLO15364.1 - 5.7e-18 65.2 0.0 1.1e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KLO15364.1 - 7.4e-12 45.8 0.0 1.3e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KLO15364.1 - 8.7e-05 22.1 0.7 0.00017 21.2 0.7 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain tRNA-synt_1e PF01406.19 KLO15365.1 - 9.9e-122 406.0 0.2 9.9e-122 406.0 0.2 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KLO15365.1 - 2.6e-07 29.7 0.5 0.00018 20.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KLO15365.1 - 3.2e-05 24.3 1.0 8.5e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 DALR domain tRNA-synt_1 PF00133.22 KLO15365.1 - 5.2e-05 21.7 0.0 0.0045 15.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 KLO15365.1 - 0.01 14.7 0.3 0.38 9.6 0.0 2.6 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DUF5106 PF17127.4 KLO15365.1 - 0.16 12.2 0.2 0.16 12.2 0.2 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5106) RXLR PF16810.5 KLO15365.1 - 8.8 6.8 9.7 87 3.5 9.7 2.5 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Kelch_4 PF13418.6 KLO15366.1 - 4e-25 87.5 7.0 7.7e-08 32.2 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KLO15366.1 - 1.8e-23 82.3 11.3 1.1e-07 31.9 0.1 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain DUF4110 PF13422.6 KLO15366.1 - 8.6e-20 70.6 0.4 8.6e-20 70.6 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 KLO15366.1 - 7.1e-18 64.2 11.3 8.1e-05 22.8 0.4 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KLO15366.1 - 3e-15 55.5 11.5 6.4e-05 22.5 0.4 5.0 4 1 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 KLO15366.1 - 1.8e-12 46.7 11.7 4.2e-05 23.4 0.3 5.0 4 1 0 4 4 4 4 Kelch motif Kelch_5 PF13854.6 KLO15366.1 - 3.2e-10 39.8 17.3 0.08 13.0 0.2 5.9 6 0 0 6 6 6 4 Kelch motif CRA PF06589.11 KLO15366.1 - 10 6.3 15.4 34 4.6 12.4 2.5 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Mito_carr PF00153.27 KLO15367.1 - 4.4e-62 206.0 2.3 2.1e-20 72.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CoA_binding_2 PF13380.6 KLO15368.1 - 7.7e-31 107.0 0.0 9.1e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CBM27 PF09212.10 KLO15368.1 - 0.18 12.0 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding module 27 zf-HIT PF04438.16 KLO15369.1 - 1.4e-08 34.5 12.2 1.9e-08 34.0 12.2 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KLO15369.1 - 0.013 15.5 9.5 0.025 14.7 9.5 1.4 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.24 KLO15369.1 - 1.2 9.3 8.7 1.9 8.7 8.7 1.3 1 0 0 1 1 1 0 B-box zinc finger Copper-fist PF00649.18 KLO15369.1 - 3.5 7.2 5.8 20 4.8 0.4 2.5 2 0 0 2 2 2 0 Copper fist DNA binding domain Peroxidase_2 PF01328.17 KLO15370.1 - 1.6e-47 162.5 0.0 2.3e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Cyt-b5 PF00173.28 KLO15372.1 - 1.7e-09 37.7 0.2 2e-09 37.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DIOX_N PF14226.6 KLO15373.1 - 1.6e-28 99.8 0.0 2.6e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO15373.1 - 7.6e-17 61.7 0.0 1.5e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KLO15374.1 - 2.4e-26 92.8 0.0 3.9e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO15374.1 - 2e-16 60.3 0.0 3.9e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peroxidase_2 PF01328.17 KLO15375.1 - 6.1e-48 163.8 0.0 8.5e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 PP2C PF00481.21 KLO15376.1 - 3.7e-46 157.8 0.0 6.1e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KLO15376.1 - 7.2e-43 144.2 65.1 2.9e-12 46.2 1.9 10.9 7 3 3 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 KLO15376.1 - 7.6e-40 134.3 68.2 2.7e-05 24.4 1.0 13.0 6 2 9 16 16 16 15 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KLO15376.1 - 6.6e-26 91.0 0.0 1.3e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_5 PF13306.6 KLO15376.1 - 8e-05 22.6 6.8 0.0076 16.2 0.1 3.8 3 1 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KLO15376.1 - 0.0029 17.1 24.6 0.37 10.3 0.1 6.3 1 1 9 10 10 10 5 Leucine-rich repeat zf-C6H2 PF15801.5 KLO15376.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding LRR_1 PF00560.33 KLO15376.1 - 0.53 11.0 60.1 2.7 8.9 0.3 15.6 17 1 1 18 18 18 0 Leucine Rich Repeat Mg_trans_NIPA PF05653.14 KLO15377.1 - 1.3e-81 274.0 29.2 1.8e-81 273.5 29.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KLO15377.1 - 3.5e-07 30.5 7.9 3.5e-07 30.5 7.9 3.9 3 1 0 3 3 3 2 EamA-like transporter family PWWP PF00855.17 KLO15379.1 - 1.1e-16 60.9 0.0 1.1e-16 60.9 0.0 2.9 1 1 1 2 2 2 1 PWWP domain Med26 PF08711.11 KLO15379.1 - 1.7e-05 24.7 0.0 4.7e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ndc1_Nup PF09531.10 KLO15379.1 - 0.64 8.6 5.2 0.78 8.4 5.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.14 KLO15379.1 - 2.6 6.2 18.1 4.7 5.4 18.1 1.5 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 KLO15379.1 - 9.7 3.1 9.1 13 2.7 9.1 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glyoxalase PF00903.25 KLO15380.1 - 2.2e-36 124.9 6.1 5.3e-22 78.4 0.7 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KLO15380.1 - 1.6e-12 47.6 1.0 8.3e-06 26.0 0.1 3.1 2 1 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KLO15380.1 - 1.6e-06 28.1 4.2 0.08 12.9 0.1 3.9 3 2 1 5 5 5 3 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KLO15380.1 - 5.1e-06 27.2 0.0 0.00047 20.9 0.0 2.7 2 2 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KLO15380.1 - 0.00019 21.6 0.0 0.41 10.7 0.0 3.1 3 0 0 3 3 3 2 Glyoxalase-like domain DAP_epimerase PF01678.19 KLO15380.1 - 0.0011 19.1 1.0 1.6 8.9 0.0 3.0 4 0 0 4 4 4 2 Diaminopimelate epimerase CHAP PF05257.16 KLO15380.1 - 0.0016 19.0 1.0 0.48 11.0 0.2 2.7 2 0 0 2 2 2 2 CHAP domain TxDE PF18711.1 KLO15380.1 - 0.03 14.4 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Toxoflavin-degrading enzyme Mg_trans_NIPA PF05653.14 KLO15381.1 - 1.7e-83 280.1 25.6 2.1e-83 279.9 25.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KLO15381.1 - 1e-07 32.2 6.9 1e-07 32.2 6.9 3.2 2 2 0 3 3 3 1 EamA-like transporter family TPR_1 PF00515.28 KLO15382.1 - 3.3e-28 96.3 6.2 1.2e-05 24.9 1.8 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KLO15382.1 - 3.1e-21 73.7 16.5 9.7e-05 22.3 0.0 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 KLO15382.1 - 2.1e-20 71.1 13.7 0.0025 17.8 2.5 7.9 8 0 0 8 8 7 5 Tetratricopeptide repeat ANAPC8 PF04049.13 KLO15382.1 - 1.6e-18 67.1 1.0 3.1e-18 66.2 1.0 1.4 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.6 KLO15382.1 - 4.8e-12 45.4 5.4 8.9e-07 28.5 0.5 4.5 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 KLO15382.1 - 7.6e-12 45.0 12.9 0.041 14.7 0.1 7.7 5 1 3 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 KLO15382.1 - 2.3e-11 43.8 12.6 0.024 14.9 0.0 6.9 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KLO15382.1 - 2.1e-09 37.9 10.1 3.1e-05 24.5 1.4 6.3 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KLO15382.1 - 2.4e-09 36.9 0.9 0.23 11.9 0.1 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KLO15382.1 - 1.8e-06 27.5 14.5 0.62 10.2 0.1 7.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KLO15382.1 - 0.00023 21.3 6.0 0.016 15.4 1.2 3.9 3 1 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KLO15382.1 - 0.004 17.7 17.0 33 5.4 0.7 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_15 PF13429.6 KLO15382.1 - 0.0058 15.9 2.1 0.021 14.1 1.9 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KLO15382.1 - 0.0065 17.0 10.9 0.43 11.1 0.1 5.3 4 1 2 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO15382.1 - 0.026 14.7 9.3 2.3 8.5 0.5 4.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 KLO15382.1 - 0.057 12.4 0.0 1.9 7.4 0.0 2.7 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Sel1 PF08238.12 KLO15382.1 - 0.12 13.1 1.1 5.7 7.8 0.0 3.5 3 0 0 3 3 3 0 Sel1 repeat TPR_10 PF13374.6 KLO15382.1 - 0.57 10.1 10.8 88 3.2 0.1 7.1 9 0 0 9 9 9 0 Tetratricopeptide repeat Glyco_hydro_79C PF16862.5 KLO15383.1 - 2.8e-16 60.3 0.4 9.1e-16 58.6 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain MARVEL PF01284.23 KLO15384.1 - 1e-05 25.6 7.6 1.4e-05 25.2 7.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain FAD_binding_4 PF01565.23 KLO15385.1 - 5.9e-16 58.5 2.7 1.3e-15 57.4 2.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KLO15385.1 - 2.3e-09 37.2 0.0 4.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Tetraspanin PF00335.20 KLO15386.1 - 4.4e-05 23.3 10.3 7.5e-05 22.6 10.3 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 KLO15386.1 - 0.037 13.8 3.3 0.056 13.2 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF2070 PF09843.9 KLO15386.1 - 4.2 5.5 8.5 6 5.0 8.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1746 PF08508.10 KLO15387.1 - 4.6e-08 33.4 0.1 7.8e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) zf-CSL PF05207.13 KLO15387.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 CSL zinc finger K_channel_TID PF07941.11 KLO15387.1 - 0.17 12.4 8.6 0.3 11.6 8.6 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain CX9C PF16860.5 KLO15388.1 - 3.3e-05 23.8 2.0 0.012 15.5 0.7 2.1 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 KLO15388.1 - 0.00027 21.1 3.9 0.00061 20.0 4.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KLO15388.1 - 0.004 17.5 2.6 0.0054 17.0 2.6 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KLO15388.1 - 0.0054 16.7 4.0 0.0077 16.2 4.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KLO15388.1 - 0.009 16.1 2.9 0.021 14.9 3.0 1.6 1 1 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 KLO15388.1 - 0.013 15.2 2.5 0.017 14.8 2.5 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.11 KLO15388.1 - 0.1 13.1 6.2 0.099 13.1 4.6 1.7 1 1 1 2 2 2 0 GCK domain Sybindin PF04099.12 KLO15389.1 - 4.4e-18 65.6 0.0 6.9e-18 64.9 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family Ubie_methyltran PF01209.18 KLO15389.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SNF2_N PF00176.23 KLO15390.1 - 2.5e-57 194.2 0.1 4.1e-57 193.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO15390.1 - 3.4e-17 62.8 0.0 8.8e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO15390.1 - 1.3e-08 35.0 0.0 2.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_3 PF12836.7 KLO15390.1 - 0.0001 22.4 0.0 0.00033 20.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif ERCC3_RAD25_C PF16203.5 KLO15390.1 - 0.00012 21.4 0.4 0.00025 20.3 0.1 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase KRAB PF01352.27 KLO15390.1 - 0.064 12.9 0.0 0.24 11.1 0.0 2.0 1 0 0 1 1 1 0 KRAB box HHH_6 PF14579.6 KLO15390.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Mito_carr PF00153.27 KLO15393.1 - 1.3e-12 47.5 0.0 1.6e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein Zn_clus PF00172.18 KLO15394.1 - 3.2e-07 30.3 6.1 6.7e-07 29.3 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCCH PF00642.24 KLO15396.1 - 3.4e-14 52.3 16.3 4.6e-07 29.6 3.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KLO15396.1 - 0.00035 20.3 0.0 0.001 18.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KLO15396.1 - 0.0064 16.5 3.3 0.0064 16.5 3.3 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 KLO15396.1 - 0.027 14.7 5.5 0.42 10.8 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger containing family Torus PF16131.5 KLO15396.1 - 0.098 13.4 6.3 1.6 9.4 0.1 2.6 2 1 0 2 2 2 0 Torus domain Alg14 PF08660.11 KLO15397.1 - 9.1e-59 198.3 0.0 1e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like GLTSCR1 PF15249.6 KLO15398.1 - 2.3e-24 85.8 0.3 3.3e-24 85.3 0.3 1.3 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein Ig_mannosidase PF17753.1 KLO15401.1 - 1.6e-14 53.4 0.1 4.9e-14 51.8 0.1 1.9 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KLO15401.1 - 4e-11 43.4 0.6 1.2e-10 41.8 0.6 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KLO15401.1 - 2.3e-05 25.0 0.0 0.00014 22.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ank_4 PF13637.6 KLO15402.1 - 7.4e-12 45.5 0.5 1.2e-06 29.0 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KLO15402.1 - 7.5e-06 26.4 0.0 1.5e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KLO15402.1 - 1.8e-05 24.9 0.1 3.5e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KLO15402.1 - 0.0021 18.4 0.0 0.0054 17.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 KLO15402.1 - 0.0023 18.3 0.1 0.018 15.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ribosomal_L11_N PF03946.14 KLO15403.1 - 9.4e-23 79.8 0.5 1.5e-22 79.2 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KLO15403.1 - 1.2e-16 60.9 0.4 2.2e-16 60.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Cyclin PF08613.11 KLO15404.1 - 6.4e-32 111.1 0.1 1.4e-31 110.0 0.1 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KLO15404.1 - 9.6e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain PseudoU_synth_2 PF00849.22 KLO15405.1 - 1.1e-27 97.1 0.0 1.8e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase WD40 PF00400.32 KLO15406.1 - 6.3e-40 134.4 24.5 1.6e-08 35.1 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO15406.1 - 7.1e-10 39.0 1.0 0.13 12.6 0.0 5.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 KLO15406.1 - 0.00013 21.2 0.0 0.013 14.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1513) Nup160 PF11715.8 KLO15406.1 - 0.00058 18.6 3.8 0.031 12.9 0.1 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 KLO15406.1 - 0.0018 18.2 1.5 6 6.9 0.0 4.7 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KLO15406.1 - 0.008 14.7 0.0 0.33 9.5 0.1 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KLO15406.1 - 0.02 13.8 0.0 21 4.0 0.0 3.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KLO15406.1 - 0.099 11.9 0.0 8.5 5.6 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Zn_clus PF00172.18 KLO15407.1 - 0.0022 18.1 11.6 0.0028 17.8 11.6 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KLO15407.1 - 1.8 9.1 10.3 3.4 8.2 1.2 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region TPT PF03151.16 KLO15410.1 - 2e-21 76.6 19.9 2.6e-21 76.2 19.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KLO15410.1 - 2.5e-09 36.8 20.5 3.3e-09 36.4 20.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KLO15410.1 - 1e-05 25.7 35.2 0.0063 16.7 11.7 2.3 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KLO15410.1 - 0.0011 18.3 15.7 0.0018 17.5 15.7 1.4 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport Fungal_trans PF04082.18 KLO15411.1 - 2.4e-12 46.4 0.5 5.4e-12 45.3 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO15411.1 - 8e-05 22.7 14.0 0.00013 22.0 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG5 PF04106.12 KLO15413.1 - 1.6e-61 207.8 0.0 2.1e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Dioxygenase_C PF00775.21 KLO15414.1 - 2.2e-44 151.1 0.0 3.2e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KLO15414.1 - 8.8e-30 102.4 0.0 1.5e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KLO15414.1 - 0.0014 18.8 0.1 0.0094 16.2 0.1 2.3 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain Peptidase_S8 PF00082.22 KLO15415.1 - 3.3e-47 161.2 1.4 4.8e-47 160.6 1.4 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KLO15415.1 - 4.8e-11 43.3 0.1 1.1e-10 42.2 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 KLO15415.1 - 0.0022 18.0 0.0 0.0058 16.6 0.0 1.7 1 0 0 1 1 1 1 PA domain Muskelin_N PF06588.11 KLO15416.1 - 3.7e-55 186.9 0.0 6.4e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_4 PF13418.6 KLO15416.1 - 7.8e-23 80.2 3.2 7.1e-06 25.9 0.1 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KLO15416.1 - 3.1e-19 68.8 5.3 1e-08 35.2 0.0 6.5 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KLO15416.1 - 8.9e-19 67.1 4.8 6.9e-07 29.1 0.0 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KLO15416.1 - 3.7e-14 52.4 3.3 2.5e-05 24.4 0.1 5.9 8 0 0 8 8 8 3 Kelch motif Kelch_1 PF01344.25 KLO15416.1 - 5e-11 42.0 6.8 3.2e-07 29.8 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 KLO15416.1 - 1.5e-07 31.1 1.4 0.00035 20.4 0.2 3.7 3 0 0 3 3 3 2 Kelch motif F5_F8_type_C PF00754.25 KLO15416.1 - 5.1e-07 29.9 0.0 1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain LPD28 PF18843.1 KLO15416.1 - 0.054 13.1 0.1 4.8 6.9 0.0 2.9 3 0 0 3 3 3 0 Large polyvalent protein associated domain 28 F-box-like PF12937.7 KLO15417.1 - 4.9e-06 26.3 1.9 2.7e-05 24.0 1.9 2.3 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KLO15417.1 - 0.017 15.1 0.1 0.043 13.8 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 KLO15418.1 - 9.8e-06 25.4 3.1 3.2e-05 23.7 2.1 2.5 2 1 0 2 2 2 1 F-box-like LRR_8 PF13855.6 KLO15418.1 - 0.011 15.5 5.2 26 4.7 0.0 6.4 9 0 0 9 9 9 0 Leucine rich repeat F-box PF00646.33 KLO15418.1 - 0.39 10.7 2.4 20 5.2 0.0 3.4 3 0 0 3 3 3 0 F-box domain DUF948 PF06103.11 KLO15419.1 - 0.001 19.3 1.0 3 8.2 0.2 3.6 3 1 1 4 4 4 1 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 KLO15419.1 - 0.0069 16.6 3.2 0.035 14.3 0.2 2.9 2 1 0 3 3 3 1 Fibrinogen alpha/beta chain family HBM PF16591.5 KLO15419.1 - 0.018 14.5 0.3 0.67 9.3 0.2 2.6 2 1 1 3 3 3 0 Helical bimodular sensor domain Apolipoprotein PF01442.18 KLO15419.1 - 0.019 14.9 6.3 1.5 8.7 6.3 2.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain S6PP_C PF08472.10 KLO15419.1 - 0.027 14.3 0.0 0.069 13.0 0.0 1.6 1 1 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal DUF1759 PF03564.15 KLO15419.1 - 0.055 13.4 0.3 8.4 6.3 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) SMODS PF18144.1 KLO15419.1 - 0.13 12.4 0.5 1.6 8.9 0.0 2.6 3 0 0 3 3 3 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain DUF1657 PF07870.11 KLO15419.1 - 0.24 11.3 3.6 1.8 8.5 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1657) Prominin PF05478.11 KLO15419.1 - 0.26 9.2 0.1 0.91 7.4 0.1 1.9 1 1 0 1 1 1 0 Prominin Goodbye PF17109.5 KLO15419.1 - 0.59 10.6 3.6 1 9.8 0.3 2.8 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain Pex19 PF04614.12 KLO15419.1 - 1.1 9.0 9.7 0.16 11.7 4.4 2.2 2 1 0 2 2 2 0 Pex19 protein family DUF2959 PF11172.8 KLO15419.1 - 1.8 8.7 5.9 4.1 7.5 0.2 3.0 1 1 0 3 3 3 0 Protein of unknown function (DUF2959) ING PF12998.7 KLO15419.1 - 2.4 8.8 6.0 2.1 9.0 0.1 3.2 4 0 0 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding DUF4600 PF15372.6 KLO15419.1 - 2.7 8.5 5.8 3.5 8.1 1.7 2.5 2 1 0 2 2 1 0 Domain of unknown function (DUF4600) ISG65-75 PF11727.8 KLO15419.1 - 3 7.0 13.3 0.51 9.5 2.5 2.7 1 1 1 2 2 2 0 Invariant surface glycoprotein ApoLp-III PF07464.11 KLO15419.1 - 3.9 7.6 12.4 1.5 8.9 1.3 3.5 1 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Sigma70_ner PF04546.13 KLO15419.1 - 5.7 6.8 10.0 0.66 9.8 0.5 3.0 1 1 3 4 4 4 0 Sigma-70, non-essential region F-box-like PF12937.7 KLO15420.1 - 0.00014 21.7 0.4 0.0007 19.4 0.4 2.2 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO15421.1 - 1.9e-06 27.6 2.7 2e-06 27.6 0.3 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO15421.1 - 0.015 15.1 0.6 2.3 8.2 0.6 2.9 2 0 0 2 2 2 0 F-box domain F-box-like_2 PF13013.6 KLO15421.1 - 0.16 11.9 1.2 0.4 10.7 0.1 2.1 2 0 0 2 2 2 0 F-box-like domain CHAD PF05235.14 KLO15421.1 - 0.17 11.8 0.8 0.24 11.3 0.1 1.5 2 0 0 2 2 2 0 CHAD domain LRR_4 PF12799.7 KLO15421.1 - 0.76 10.3 6.5 1.8 9.1 0.1 4.5 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO15422.1 - 2.2e-06 27.4 0.3 9.2e-06 25.5 0.3 2.1 2 0 0 2 2 2 1 F-box-like RICH PF05062.12 KLO15422.1 - 0.82 10.1 2.3 21 5.5 0.1 2.8 3 0 0 3 3 3 0 RICH domain Arrestin_N PF00339.29 KLO15423.1 - 2.4e-11 43.9 0.0 4.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KLO15423.1 - 2.1e-05 25.0 0.0 0.02 15.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KLO15423.1 - 9.3e-05 22.2 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Pyridoxal_deC PF00282.19 KLO15424.1 - 3.8e-16 58.8 0.0 7.2e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KLO15424.1 - 4.3e-09 35.8 0.0 2.7e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KLO15424.1 - 0.0058 16.0 0.1 0.0087 15.4 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KLO15424.1 - 0.074 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Prefoldin_2 PF01920.20 KLO15425.1 - 7.6e-21 74.1 1.1 1.1e-20 73.6 1.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF465 PF04325.13 KLO15425.1 - 0.013 15.5 7.6 0.18 11.9 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF465) ZapB PF06005.12 KLO15425.1 - 0.014 15.8 0.8 0.014 15.8 0.8 1.9 1 1 1 2 2 2 0 Cell division protein ZapB 5_nucleotid PF05761.14 KLO15425.1 - 0.025 13.5 1.6 0.029 13.3 1.6 1.0 1 0 0 1 1 1 0 5' nucleotidase family DivIC PF04977.15 KLO15425.1 - 0.043 13.6 3.2 2.6 7.9 0.5 2.4 2 1 0 2 2 2 0 Septum formation initiator GAS PF13851.6 KLO15425.1 - 0.045 13.1 6.4 0.11 11.9 2.1 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DASH_Dam1 PF08653.10 KLO15425.1 - 0.052 13.4 0.8 6.3 6.7 0.0 2.6 2 1 0 2 2 2 0 DASH complex subunit Dam1 DUF5082 PF16888.5 KLO15425.1 - 0.058 13.7 1.5 1.9 8.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) FTR PF01913.18 KLO15425.1 - 0.07 13.1 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Prefoldin PF02996.17 KLO15425.1 - 0.071 13.0 3.5 2.6 8.0 0.6 2.2 1 1 1 2 2 2 0 Prefoldin subunit Sipho_Gp157 PF05565.11 KLO15425.1 - 0.16 12.0 7.5 0.31 11.1 0.4 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 DUF4140 PF13600.6 KLO15425.1 - 0.45 11.0 4.8 2.6 8.5 0.5 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.8 KLO15425.1 - 0.84 9.7 9.0 1.9 8.6 0.3 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4337 PF14235.6 KLO15425.1 - 3.3 7.8 6.0 15 5.7 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) COesterase PF00135.28 KLO15426.1 - 5.3e-84 282.9 0.0 6.3e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO15426.1 - 1.3e-07 31.7 0.1 7.3e-07 29.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Erf4 PF10256.9 KLO15427.1 - 0.0028 17.8 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family peroxidase PF00141.23 KLO15428.1 - 6.8e-46 156.8 0.0 1.2e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase FAD_binding_3 PF01494.19 KLO15429.1 - 1.6e-66 225.0 0.0 2.1e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KLO15429.1 - 2.5e-06 27.4 0.3 0.0043 16.7 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KLO15429.1 - 0.0056 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KLO15429.1 - 0.0073 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO15429.1 - 0.016 14.5 0.1 0.029 13.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO15429.1 - 0.031 13.0 0.0 0.058 12.1 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KLO15429.1 - 0.04 12.8 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.6 KLO15429.1 - 0.05 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KLO15429.1 - 0.088 12.8 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KLO15429.1 - 0.098 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 KLO15429.1 - 0.13 12.7 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding F-box-like PF12937.7 KLO15430.1 - 2.7e-07 30.4 0.1 6.5e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO15430.1 - 0.00085 19.1 0.3 0.0053 16.6 0.3 2.3 1 1 0 1 1 1 1 F-box domain Rv2175c_C PF18367.1 KLO15431.1 - 0.033 14.3 0.1 0.043 13.9 0.1 1.4 1 1 0 1 1 1 0 Rv2175c C-terminal domain of unknown function F-box-like PF12937.7 KLO15432.1 - 0.041 13.8 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 F-box-like tRNA_synthFbeta PF17759.1 KLO15432.1 - 0.086 12.3 0.1 0.28 10.6 0.1 1.7 2 0 0 2 2 2 0 Phenylalanyl tRNA synthetase beta chain CLM domain F-box-like PF12937.7 KLO15433.1 - 0.0017 18.2 0.2 0.0075 16.1 0.1 2.1 2 1 1 3 3 3 1 F-box-like Herpes_gE PF02480.16 KLO15434.1 - 0.075 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Inhibitor_I24 PF10465.9 KLO15435.1 - 0.06 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 PinA peptidase inhibitor F-box-like PF12937.7 KLO15436.1 - 0.055 13.4 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like DUF4254 PF14063.6 KLO15436.1 - 0.097 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) F-box PF00646.33 KLO15436.1 - 0.11 12.4 0.1 0.36 10.8 0.1 2.0 1 0 0 1 1 1 0 F-box domain Cor1 PF04803.12 KLO15436.1 - 0.12 12.6 0.0 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region F-box-like PF12937.7 KLO15437.1 - 0.031 14.2 0.1 0.11 12.4 0.1 2.0 1 0 0 1 1 1 0 F-box-like DMA PF03474.14 KLO15437.1 - 0.065 12.8 0.1 0.58 9.8 0.0 2.4 2 0 0 2 2 2 0 DMRTA motif T3SS_ExsE PF18286.1 KLO15437.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Type III secretion system ExsE F-box-like PF12937.7 KLO15438.1 - 0.024 14.5 0.1 0.24 11.3 0.0 2.6 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 KLO15439.1 - 0.014 15.3 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KLO15439.1 - 0.047 13.6 0.8 0.37 10.7 0.1 2.7 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO15440.1 - 0.004 17.0 2.5 0.14 12.0 0.1 2.8 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KLO15440.1 - 0.25 11.3 7.7 5.8 6.9 2.5 3.6 3 0 0 3 3 3 0 F-box domain NUFIP2 PF15293.6 KLO15440.1 - 0.33 9.8 0.2 0.46 9.3 0.2 1.1 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 F-box-like PF12937.7 KLO15441.1 - 0.0051 16.7 0.2 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like Dehydratase_LU PF02286.15 KLO15441.1 - 0.12 10.9 0.0 0.23 10.0 0.0 1.3 1 0 0 1 1 1 0 Dehydratase large subunit F-box PF00646.33 KLO15441.1 - 0.79 9.7 4.7 1.1 9.3 0.1 3.0 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO15442.1 - 0.013 15.4 0.0 0.042 13.8 0.0 2.0 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KLO15443.1 - 0.0048 16.8 0.0 0.014 15.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like Cep57_CLD_2 PF14197.6 KLO15444.1 - 2 8.6 3.8 1.3 9.2 1.7 1.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ABC_tran PF00005.27 KLO15446.1 - 2.8e-41 141.2 0.0 3.7e-19 69.6 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KLO15446.1 - 9.1e-18 65.1 0.6 5.6e-06 26.4 0.2 4.3 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KLO15446.1 - 2.7e-13 49.9 0.5 0.0017 17.9 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KLO15446.1 - 3.9e-08 32.9 0.3 0.0046 16.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KLO15446.1 - 6.1e-06 26.9 6.0 0.013 16.0 0.0 3.0 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KLO15446.1 - 1.2e-05 25.4 0.1 0.14 12.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 KLO15446.1 - 2.1e-05 24.7 0.1 0.0065 16.6 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KLO15446.1 - 2.4e-05 24.6 0.0 0.12 12.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KLO15446.1 - 3.2e-05 24.5 0.1 0.015 15.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KLO15446.1 - 4.4e-05 23.4 0.1 0.085 12.7 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase HEAT_2 PF13646.6 KLO15446.1 - 5.3e-05 23.5 9.5 0.037 14.4 0.1 3.7 3 1 0 3 3 2 2 HEAT repeats AAA_15 PF13175.6 KLO15446.1 - 0.00011 22.0 0.4 0.29 10.8 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain Chromo PF00385.24 KLO15446.1 - 0.00019 21.2 0.3 0.00052 19.9 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.6 KLO15446.1 - 0.00026 21.3 0.0 0.55 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KLO15446.1 - 0.00041 20.8 0.7 0.16 12.3 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KLO15446.1 - 0.00042 20.3 0.1 0.56 10.1 0.0 2.7 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 KLO15446.1 - 0.00047 20.5 0.0 1.8 9.0 0.0 3.1 2 0 0 2 2 2 2 RNA helicase 4HB PF17947.1 KLO15446.1 - 0.00048 20.1 0.0 0.0026 17.8 0.0 2.3 2 0 0 2 2 1 1 Four helical bundle domain AAA_33 PF13671.6 KLO15446.1 - 0.00079 19.6 0.0 0.89 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KLO15446.1 - 0.0011 19.3 0.0 4.4 7.7 0.0 3.4 4 0 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KLO15446.1 - 0.0014 18.4 0.3 2.8 7.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 KLO15446.1 - 0.0025 16.8 0.8 0.33 9.9 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KLO15446.1 - 0.0076 16.0 0.0 1.6 8.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 KLO15446.1 - 0.012 14.9 0.2 2.6 7.2 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_13 PF13166.6 KLO15446.1 - 0.013 14.1 0.0 1.4 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KLO15446.1 - 0.014 15.3 0.4 9.4 6.1 0.1 3.5 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea Roc PF08477.13 KLO15446.1 - 0.017 15.3 0.0 6.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KLO15446.1 - 0.025 13.8 0.4 3.8 6.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KLO15446.1 - 0.025 14.1 0.4 4.7 6.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KLO15446.1 - 0.029 14.6 1.1 7 7.0 0.0 3.6 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit HEAT_EZ PF13513.6 KLO15446.1 - 0.029 14.9 6.4 8 7.1 0.0 4.6 4 1 0 4 4 3 0 HEAT-like repeat AAA_27 PF13514.6 KLO15446.1 - 0.086 12.4 0.1 11 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain HEAT PF02985.22 KLO15446.1 - 0.1 12.9 8.5 1.3 9.5 0.1 4.8 4 0 0 4 4 4 0 HEAT repeat DUF3437 PF11919.8 KLO15446.1 - 0.11 12.4 0.9 0.61 10.0 0.1 2.8 2 1 0 2 2 1 0 Domain of unknown function (DUF3437) NTPase_1 PF03266.15 KLO15446.1 - 0.12 12.3 0.2 16 5.4 0.1 2.8 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 KLO15446.1 - 0.15 12.1 2.2 14 5.7 0.2 3.0 3 1 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KLO15446.1 - 0.16 11.5 0.2 14 5.2 0.1 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CLP1_P PF16575.5 KLO15446.1 - 0.17 11.6 2.3 16 5.2 0.1 3.0 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop U3snoRNP10 PF12397.8 KLO15446.1 - 0.4 11.0 1.7 1.5 9.2 1.7 2.1 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 AAA_5 PF07728.14 KLO15446.1 - 0.8 9.7 4.6 16 5.5 0.1 3.8 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) V_ATPase_I PF01496.19 KLO15447.1 - 0 1034.7 0.0 0 1034.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family F-box-like PF12937.7 KLO15448.1 - 3.8e-06 26.7 5.0 3.9e-06 26.7 2.2 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO15448.1 - 0.27 11.7 4.2 22 5.7 0.0 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Acyl-CoA_dh_M PF02770.19 KLO15450.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_M PF02770.19 KLO15452.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KLO15452.1 - 0.028 14.6 0.1 0.047 13.9 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain F-box-like PF12937.7 KLO15453.1 - 0.05 13.5 0.3 0.27 11.1 0.1 2.2 2 0 0 2 2 2 0 F-box-like Vps16_N PF04841.13 KLO15454.1 - 0.13 11.0 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 Vps16, N-terminal region Acyl-CoA_dh_M PF02770.19 KLO15455.1 - 0.0037 17.4 0.0 0.0096 16.1 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF3974 PF13120.6 KLO15455.1 - 0.025 14.7 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) RhoGEF PF00621.20 KLO15456.1 - 8.7e-44 149.9 2.6 5.9e-43 147.2 1.9 2.3 2 0 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.28 KLO15456.1 - 3.1e-18 65.1 0.1 8.1e-10 38.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KLO15456.1 - 1.8e-17 63.0 0.9 3.4e-08 33.2 0.3 2.6 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.7 KLO15456.1 - 1e-16 60.7 0.0 2.8e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand PH_13 PF16652.5 KLO15456.1 - 1.2e-12 48.0 0.3 2.6e-10 40.3 0.3 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain WH2 PF02205.20 KLO15456.1 - 3.6e-09 36.2 0.1 8.7e-09 34.9 0.1 1.7 1 0 0 1 1 1 1 WH2 motif SH3_2 PF07653.17 KLO15456.1 - 1.2e-08 34.4 0.0 0.00097 18.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_1 PF00036.32 KLO15456.1 - 3.7e-06 26.1 0.0 0.012 15.1 0.0 3.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KLO15456.1 - 0.00022 21.0 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair PH PF00169.29 KLO15456.1 - 0.00049 20.6 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 PH domain EF-hand_6 PF13405.6 KLO15456.1 - 0.0066 16.3 0.1 5.9 7.1 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain IQ_SEC7_PH PF16453.5 KLO15456.1 - 0.0072 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 PH domain Importin_rep_4 PF18808.1 KLO15456.1 - 0.77 10.1 7.2 1.2 9.5 0.2 3.0 2 0 0 2 2 2 0 Importin repeat F-box-like PF12937.7 KLO15459.1 - 3.4e-07 30.0 1.3 9.8e-07 28.6 1.3 1.9 1 0 0 1 1 1 1 F-box-like DUF2101 PF09874.9 KLO15460.1 - 0.06 13.0 0.7 6.3 6.5 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) DUF1106 PF06523.11 KLO15460.1 - 0.071 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) F-box-like PF12937.7 KLO15463.1 - 3e-07 30.2 1.5 1.2e-06 28.3 1.5 2.2 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO15463.1 - 0.007 16.8 1.2 21 5.7 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) NACHT PF05729.12 KLO15466.1 - 2.3e-17 63.4 0.0 3e-08 33.8 0.0 4.3 2 2 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO15466.1 - 1.6e-11 44.9 0.0 2.4e-05 24.8 0.0 3.6 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 KLO15466.1 - 5e-08 33.3 0.0 0.0033 17.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KLO15466.1 - 1.2e-06 29.0 0.0 0.0095 16.4 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KLO15466.1 - 1.8e-06 27.3 0.0 0.047 12.9 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain RNA_helicase PF00910.22 KLO15466.1 - 5e-06 26.9 0.0 0.022 15.1 0.0 2.9 3 0 0 3 3 2 2 RNA helicase DUF2075 PF09848.9 KLO15466.1 - 3.3e-05 23.3 0.0 0.13 11.5 0.0 2.7 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KLO15466.1 - 0.00024 20.9 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KLO15466.1 - 0.00028 21.2 0.0 0.35 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KLO15466.1 - 0.00056 20.1 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KLO15466.1 - 0.0006 20.4 0.0 0.5 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KLO15466.1 - 0.00077 18.9 0.0 0.58 9.5 0.0 2.5 2 0 0 2 2 2 2 KaiC APS_kinase PF01583.20 KLO15466.1 - 0.00096 19.1 0.0 0.64 9.9 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase DnaB_C PF03796.15 KLO15466.1 - 0.001 18.5 0.0 1 8.6 0.0 3.1 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 KLO15466.1 - 0.0011 18.3 0.0 0.23 10.7 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 KLO15466.1 - 0.0017 18.4 0.0 0.53 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 KLO15466.1 - 0.0019 17.4 0.1 0.63 9.1 0.1 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Torsin PF06309.11 KLO15466.1 - 0.0038 17.3 0.0 0.027 14.6 0.0 2.2 2 0 0 2 2 2 1 Torsin cobW PF02492.19 KLO15466.1 - 0.004 16.7 0.0 0.38 10.3 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KLO15466.1 - 0.005 16.4 0.0 14 5.2 0.0 3.3 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_30 PF13604.6 KLO15466.1 - 0.0058 16.4 0.0 0.79 9.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KLO15466.1 - 0.0061 16.3 0.0 0.89 9.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KLO15466.1 - 0.0072 16.1 0.0 0.38 10.5 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KLO15466.1 - 0.0073 15.9 0.0 4.2 6.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.14 KLO15466.1 - 0.0077 15.5 0.6 1 8.5 0.0 3.4 4 0 0 4 4 4 1 KAP family P-loop domain TsaE PF02367.17 KLO15466.1 - 0.0078 16.2 0.0 6.2 6.8 0.0 3.0 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KLO15466.1 - 0.0082 16.6 0.1 4.9 7.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 KLO15466.1 - 0.0089 15.9 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_28 PF13521.6 KLO15466.1 - 0.013 15.7 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KLO15466.1 - 0.017 14.9 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KLO15466.1 - 0.019 14.9 0.0 0.99 9.3 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain RuvB_N PF05496.12 KLO15466.1 - 0.027 14.2 0.0 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KLO15466.1 - 0.056 13.9 0.0 6.9 7.2 0.0 2.9 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 KLO15466.1 - 0.13 12.1 0.0 3 7.7 0.0 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea CbiA PF01656.23 KLO15466.1 - 0.15 12.1 0.1 1.6 8.8 0.0 2.8 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TIP49 PF06068.13 KLO15466.1 - 0.16 11.1 0.0 5.8 6.0 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain PIF1 PF05970.14 KLO15466.1 - 0.21 10.7 0.0 4.3 6.4 0.0 2.5 3 0 0 3 3 3 0 PIF1-like helicase HPHLAWLY PF14925.6 KLO15468.1 - 3.8 6.1 14.7 10 4.7 14.7 1.6 1 1 0 1 1 1 0 Domain of unknown function KDZ PF18758.1 KLO15469.1 - 2e-60 204.2 0.0 3.6e-60 203.4 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO15469.1 - 6.7e-32 109.8 0.2 1.8e-31 108.5 0.2 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KLO15469.1 - 0.0089 16.2 0.5 0.025 14.7 0.1 1.9 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CEBP_ZZ PF16366.5 KLO15469.1 - 0.38 11.0 3.5 1.1 9.6 3.5 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Pex14_N PF04695.13 KLO15473.1 - 9.6 6.8 10.4 0.65 10.7 4.0 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region F-box-like PF12937.7 KLO15477.1 - 6.6e-09 35.5 1.8 2.4e-08 33.7 0.5 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO15477.1 - 0.3 11.0 7.6 0.93 9.5 1.7 3.8 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO15478.1 - 4.1e-10 39.4 0.3 1.1e-09 38.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO15478.1 - 4.3e-07 29.6 0.6 4.3e-07 29.6 0.6 2.9 3 0 0 3 3 3 1 F-box domain NACHT PF05729.12 KLO15480.1 - 4.6e-18 65.7 1.7 3.1e-09 37.0 0.1 4.4 2 2 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO15480.1 - 1.1e-11 45.4 0.1 3.7e-05 24.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain Pkinase_Tyr PF07714.17 KLO15480.1 - 4.4e-11 42.6 0.0 9.4e-10 38.2 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase NB-ARC PF00931.22 KLO15480.1 - 4.2e-09 36.0 0.0 0.00034 19.9 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.6 KLO15480.1 - 3.5e-07 30.6 0.0 0.04 14.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KLO15480.1 - 2.5e-06 27.6 0.0 0.00037 20.5 0.0 2.8 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Pkinase PF00069.25 KLO15480.1 - 6.1e-06 25.8 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain AAA PF00004.29 KLO15480.1 - 4.3e-05 23.9 0.0 1.3 9.4 0.0 4.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KLO15480.1 - 5.8e-05 23.0 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase RNA_helicase PF00910.22 KLO15480.1 - 0.00058 20.2 0.0 1.4 9.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase DUF2075 PF09848.9 KLO15480.1 - 0.00063 19.1 0.0 0.29 10.3 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KLO15480.1 - 0.00081 18.7 0.0 0.013 14.8 0.0 2.4 3 0 0 3 3 2 1 Zeta toxin AAA_18 PF13238.6 KLO15480.1 - 0.0009 19.8 0.0 2.2 8.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain KAP_NTPase PF07693.14 KLO15480.1 - 0.0046 16.2 2.5 0.42 9.8 0.1 3.3 4 0 0 4 4 4 1 KAP family P-loop domain Parvo_NS1 PF01057.17 KLO15480.1 - 0.0087 15.2 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 KLO15480.1 - 0.011 15.5 0.0 1.6 8.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KLO15480.1 - 0.016 14.9 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 KLO15480.1 - 0.016 15.6 0.0 5.2 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 KLO15480.1 - 0.045 12.9 0.0 0.21 10.7 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase AAA_14 PF13173.6 KLO15480.1 - 0.091 12.8 0.0 8.8 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KLO15480.1 - 0.091 12.9 0.1 18 5.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KLO15480.1 - 0.096 12.6 0.0 19 5.1 0.0 2.5 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.18 KLO15480.1 - 0.096 12.4 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KLO15480.1 - 0.11 12.2 0.0 19 4.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KLO15480.1 - 0.14 11.3 0.0 7 5.7 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain ABC_tran PF00005.27 KLO15480.1 - 0.18 12.3 0.0 66 4.0 0.0 3.2 4 0 0 4 4 3 0 ABC transporter Pkinase_Tyr PF07714.17 KLO15481.1 - 1.5e-12 47.4 0.0 2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO15481.1 - 1.4e-08 34.5 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DASH_Dad2 PF08654.10 KLO15484.1 - 0.086 13.3 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad2 Terminase_2 PF03592.16 KLO15484.1 - 0.21 12.1 1.1 0.23 11.9 0.2 1.6 2 0 0 2 2 2 0 Terminase small subunit NACHT PF05729.12 KLO15485.1 - 2.3e-08 34.1 0.5 2.4e-06 27.6 0.2 3.2 2 1 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 KLO15485.1 - 6.8e-06 25.4 0.1 1.9e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 KLO15485.1 - 6.4e-05 23.4 0.0 0.00017 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KLO15485.1 - 0.00067 20.1 0.0 0.035 14.5 0.0 3.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KLO15485.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KLO15485.1 - 0.01 16.1 0.0 0.057 13.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KLO15485.1 - 0.024 15.2 0.0 0.69 10.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 KLO15485.1 - 0.035 13.3 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 KLO15485.1 - 0.059 12.6 0.4 0.29 10.3 0.1 2.1 3 0 0 3 3 3 0 KAP family P-loop domain APS_kinase PF01583.20 KLO15485.1 - 0.071 13.0 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 KLO15485.1 - 0.1 12.3 0.1 3.4 7.3 0.0 3.2 4 0 0 4 4 4 0 AAA domain Torsin PF06309.11 KLO15485.1 - 0.19 11.9 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 0 Torsin Pkinase_Tyr PF07714.17 KLO15486.1 - 3.1e-22 79.1 0.0 4.2e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO15486.1 - 2.6e-16 59.8 0.0 3.2e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO15486.1 - 0.00079 18.8 0.0 0.001 18.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO15486.1 - 0.0018 17.9 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Sm_like PF16243.5 KLO15486.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Sm_like domain HisKA_2 PF07568.12 KLO15490.1 - 0.066 13.3 0.0 0.22 11.6 0.0 2.0 1 1 0 1 1 1 0 Histidine kinase NACHT PF05729.12 KLO15491.1 - 6.7e-07 29.4 0.5 2.3e-05 24.4 0.5 2.4 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KLO15491.1 - 6e-06 25.6 0.0 4.3e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 KLO15491.1 - 9.1e-05 22.9 0.0 0.00028 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KLO15491.1 - 9.2e-05 22.9 0.1 0.0013 19.2 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KLO15491.1 - 0.00063 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.20 KLO15491.1 - 0.00084 19.3 0.0 0.004 17.0 0.0 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase KAP_NTPase PF07693.14 KLO15491.1 - 0.0042 16.4 0.1 0.53 9.5 0.1 2.2 2 0 0 2 2 2 2 KAP family P-loop domain RNA_helicase PF00910.22 KLO15491.1 - 0.0097 16.3 0.0 0.049 14.0 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 KLO15491.1 - 0.013 16.1 0.0 0.055 14.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain Torsin PF06309.11 KLO15491.1 - 0.017 15.2 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Torsin DUF2075 PF09848.9 KLO15491.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KLO15491.1 - 0.081 13.2 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KLO15491.1 - 0.083 12.5 0.0 8.9 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Pkinase_Tyr PF07714.17 KLO15492.1 - 4.1e-13 49.2 0.2 4.9e-13 48.9 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO15492.1 - 2.2e-09 37.1 0.0 2.6e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain zf-C2H2_assoc PF16606.5 KLO15495.1 - 0.021 15.0 0.6 0.036 14.3 0.6 1.3 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers LEP503 PF15221.6 KLO15495.1 - 1.5 9.2 5.1 0.76 10.1 2.6 1.9 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 Gemini_AC4_5_2 PF08464.10 KLO15498.1 - 0.13 12.3 1.4 0.24 11.4 1.4 1.4 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region MGC-24 PF05283.11 KLO15498.1 - 1.6 9.2 4.8 6.4 7.2 0.3 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPI-anchored PF10342.9 KLO15499.1 - 3.8e-05 24.3 0.0 4.8e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HLH PF00010.26 KLO15502.1 - 2.2e-11 43.5 0.2 4.4e-11 42.6 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Urm1 PF09138.11 KLO15503.1 - 8.7e-31 106.1 0.0 2.9e-28 98.1 0.0 2.0 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KLO15503.1 - 7e-06 26.6 0.0 1e-05 26.1 0.0 1.2 1 0 0 1 1 1 1 ThiS family GTP1_OBG PF01018.22 KLO15504.1 - 1.5e-39 135.1 3.4 9e-29 100.1 1.0 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KLO15504.1 - 1.6e-17 63.6 0.0 3.8e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KLO15504.1 - 0.00055 19.5 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 KLO15504.1 - 0.00082 18.9 0.1 0.85 9.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 KLO15504.1 - 0.0016 18.0 0.1 0.3 10.6 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.19 KLO15504.1 - 0.0021 17.6 0.1 2.4 7.7 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KLO15504.1 - 0.0077 16.8 1.2 0.014 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KLO15504.1 - 0.014 14.4 0.1 0.98 8.3 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ploopntkinase3 PF18751.1 KLO15504.1 - 0.093 12.6 0.4 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KLO15504.1 - 0.097 13.2 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 KLO15504.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.8 1 1 0 1 1 1 0 Dynamin family Gtr1_RagA PF04670.12 KLO15504.1 - 0.19 11.0 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region p450 PF00067.22 KLO15505.1 - 2.1e-73 247.7 0.0 2.4e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro-kuma_activ PF09286.11 KLO15506.1 - 1.4e-44 151.9 0.1 2.1e-44 151.3 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KLO15506.1 - 3.8e-05 23.1 0.5 6.2e-05 22.4 0.5 1.2 1 0 0 1 1 1 1 Subtilase family DNA_pol_A_exo1 PF01612.20 KLO15508.1 - 7.2e-13 48.6 0.0 3.1e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease Aminotran_1_2 PF00155.21 KLO15510.1 - 8.1e-39 133.8 0.0 1.1e-38 133.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KLO15510.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase DUF4699 PF15770.5 KLO15511.1 - 1.9 8.2 5.4 3.5 7.3 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) Copper-fist PF00649.18 KLO15512.1 - 1.2e-23 82.3 1.1 1.2e-23 82.3 1.1 2.2 1 1 1 2 2 2 1 Copper fist DNA binding domain zinc-ribbons_6 PF07191.12 KLO15512.1 - 0.003 17.5 3.3 0.0041 17.1 3.3 1.3 1 0 0 1 1 1 1 zinc-ribbons Ornatin PF02088.15 KLO15512.1 - 0.0044 16.8 3.8 0.0081 15.9 2.2 2.1 1 1 1 2 2 2 1 Ornatin LTP_2 PF14368.6 KLO15512.1 - 0.058 13.5 3.1 0.07 13.2 3.1 1.2 1 0 0 1 1 1 0 Probable lipid transfer DnaJ PF00226.31 KLO15514.1 - 7.6e-18 64.4 0.3 2.1e-17 63.0 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain SpoVR PF04293.13 KLO15514.1 - 0.65 8.6 7.6 1.4 7.6 7.6 1.6 1 0 0 1 1 1 0 SpoVR like protein SUZ PF12752.7 KLO15515.1 - 1.8e-10 41.4 4.5 1.8e-10 41.4 4.5 2.4 2 1 1 3 3 3 1 SUZ domain Peptidase_M20 PF01546.28 KLO15516.1 - 1.7e-33 116.1 0.0 2.3e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KLO15516.1 - 2e-11 43.8 0.0 3.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Mito_carr PF00153.27 KLO15517.1 - 9.6e-66 217.8 8.6 4.2e-24 84.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pro-kuma_activ PF09286.11 KLO15518.1 - 2.3e-45 154.4 0.0 6.2e-45 153.0 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KLO15518.1 - 0.0003 20.2 0.4 0.0005 19.4 0.4 1.3 1 0 0 1 1 1 1 Subtilase family Adenyl_cycl_N PF12633.7 KLO15518.1 - 0.0027 17.6 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 2 Adenylate cyclase NT domain Dynamin_N PF00350.23 KLO15519.1 - 8.8e-13 48.6 0.0 1.2e-11 45.0 0.0 2.7 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KLO15519.1 - 7e-05 22.9 0.0 0.0028 17.7 0.0 3.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KLO15519.1 - 0.074 12.4 0.4 2.8 7.2 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family PI_PP_I PF18363.1 KLO15519.1 - 0.14 12.3 0.2 0.5 10.6 0.2 2.0 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain eRF1_3 PF03465.15 KLO15519.1 - 0.45 11.0 3.6 0.45 11.0 0.2 2.6 3 0 0 3 3 3 0 eRF1 domain 3 Zn_clus PF00172.18 KLO15520.1 - 3.3e-05 23.9 9.1 6.4e-05 23.0 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KLO15520.1 - 8.2e-05 21.8 0.0 0.00018 20.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KLO15521.1 - 1.8e-33 115.7 0.0 7.7e-33 113.6 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO15521.1 - 1.8e-05 24.8 12.9 3e-05 24.0 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro-kuma_activ PF09286.11 KLO15522.1 - 1.1e-46 158.7 0.0 2e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KLO15522.1 - 0.0048 16.2 0.6 0.0083 15.4 0.6 1.4 1 0 0 1 1 1 1 Subtilase family APC_u13 PF16634.5 KLO15522.1 - 0.14 12.1 0.1 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr and SAMP Complex1_LYR PF05347.15 KLO15523.1 - 6.3e-05 22.9 0.2 0.00032 20.7 0.2 2.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Dimer_Tnp_hAT PF05699.14 KLO15523.1 - 0.0097 15.7 0.1 0.03 14.1 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region EST1_DNA_bind PF10373.9 KLO15524.1 - 5.4e-34 118.0 0.0 8.5e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KLO15524.1 - 3.1e-25 89.4 0.3 1.3e-24 87.4 0.5 2.0 2 0 0 2 2 2 1 Telomerase activating protein Est1 Lin-8 PF03353.15 KLO15524.1 - 0.13 11.8 2.0 0.27 10.8 2.0 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist UCH PF00443.29 KLO15525.1 - 6.5e-11 42.2 0.0 2.9e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KLO15525.1 - 9.7e-07 28.5 0.0 6.2e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.20 KLO15525.1 - 1.1e-05 25.0 2.6 0.059 13.3 0.1 3.2 2 0 0 2 2 2 2 Ubiquitin interaction motif CUE PF02845.16 KLO15525.1 - 0.00021 20.9 0.0 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 1 CUE domain RecG_N PF17190.4 KLO15525.1 - 0.036 14.8 0.2 0.11 13.2 0.2 1.9 1 0 0 1 1 1 0 RecG N-terminal helical domain DUF4140 PF13600.6 KLO15525.1 - 0.075 13.5 0.5 5.4 7.5 0.2 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) UCH_1 PF13423.6 KLO15525.1 - 0.13 11.8 0.0 8.6 5.8 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DivIC PF04977.15 KLO15525.1 - 0.27 11.0 3.8 10 5.9 0.0 4.4 4 1 1 5 5 5 0 Septum formation initiator Phage_GP20 PF06810.11 KLO15525.1 - 0.58 10.0 4.2 15 5.4 0.1 2.7 3 0 0 3 3 3 0 Phage minor structural protein GP20 Aminotran_1_2 PF00155.21 KLO15526.1 - 1.9e-54 185.3 0.0 1.1e-45 156.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KLO15526.1 - 0.00074 18.9 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 KLO15526.1 - 0.037 12.8 0.0 0.071 11.8 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain UQ_con PF00179.26 KLO15527.1 - 1.2e-49 167.5 0.0 1.4e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KLO15527.1 - 0.00089 19.0 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UDPG_MGDP_dh_N PF03721.14 KLO15528.1 - 5.5e-60 202.2 0.0 9e-60 201.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KLO15528.1 - 2.6e-34 117.8 0.0 1.9e-33 115.0 0.1 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KLO15528.1 - 4.2e-30 103.8 0.0 8e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain F420_oxidored PF03807.17 KLO15528.1 - 0.024 15.2 0.1 0.87 10.2 0.0 3.1 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KLO15528.1 - 0.1 12.8 0.0 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KLO15528.1 - 0.14 12.4 0.0 2.6 8.2 0.0 2.6 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ribosomal_S17e PF00833.18 KLO15530.1 - 3.3e-59 198.2 0.3 3.9e-59 197.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S8 PF00410.19 KLO15531.1 - 5.7e-23 81.3 0.0 7.1e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Whi5 PF08528.11 KLO15532.1 - 4e-09 35.9 1.8 4e-09 35.9 1.8 1.7 2 0 0 2 2 2 1 Whi5 like mono-CXXC PF15626.6 KLO15532.1 - 1.8 9.0 7.1 9 6.7 0.1 3.2 2 1 0 2 2 2 0 single CXXC unit BAF1_ABF1 PF04684.13 KLO15533.1 - 0.016 14.3 0.8 0.02 13.9 0.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RbsD_FucU PF05025.13 KLO15533.1 - 0.085 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 RbsD / FucU transport protein family zf-CCHC_5 PF14787.6 KLO15535.1 - 2.3e-05 24.0 0.7 3.7e-05 23.3 0.7 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KLO15535.1 - 0.002 18.0 0.2 0.0035 17.3 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KLO15535.1 - 0.0048 16.9 1.0 0.0065 16.5 1.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KLO15535.1 - 0.025 14.4 0.6 0.034 14.0 0.6 1.2 1 0 0 1 1 1 0 Zinc knuckle NDT80_PhoG PF05224.12 KLO15536.1 - 0.018 15.3 0.3 0.051 13.8 0.3 1.8 1 1 0 1 1 1 0 NDT80 / PhoG like DNA-binding family Mre11_DNA_bind PF04152.14 KLO15537.1 - 1.1e-47 162.5 0.0 1.1e-47 162.5 0.0 2.5 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KLO15537.1 - 8.5e-15 55.8 0.1 1.7e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KLO15537.1 - 1.8e-06 28.2 0.0 3.9e-05 23.9 0.0 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain F-box-like PF12937.7 KLO15538.1 - 0.045 13.7 0.5 0.17 11.8 0.2 2.2 2 0 0 2 2 2 0 F-box-like DUF5572 PF17733.1 KLO15539.1 - 1.6e-14 53.4 0.3 2.7e-14 52.7 0.3 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5572) SNF2_N PF00176.23 KLO15540.1 - 2.9e-71 240.0 0.1 5.3e-71 239.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO15540.1 - 9.9e-21 74.2 0.0 2.9e-20 72.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO15540.1 - 0.00041 20.4 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KLO15540.1 - 0.028 13.6 0.0 0.063 12.5 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 KLO15540.1 - 0.03 14.0 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase IBB PF01749.20 KLO15540.1 - 0.09 13.2 0.5 1.6 9.2 0.0 2.8 2 0 0 2 2 2 0 Importin beta binding domain zf-TFIIB PF13453.6 KLO15540.1 - 0.16 11.3 2.0 0.31 10.4 2.0 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger Epimerase PF01370.21 KLO15541.1 - 8.5e-51 172.7 0.0 1.1e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO15541.1 - 1.6e-11 44.2 0.3 6.6e-11 42.2 0.3 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KLO15541.1 - 0.00021 20.5 0.0 0.00044 19.5 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KLO15541.1 - 0.0013 17.8 0.0 0.0026 16.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KLO15541.1 - 0.0037 16.4 4.3 0.063 12.4 3.4 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KLO15541.1 - 0.045 12.9 0.2 0.34 10.0 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein GDP_Man_Dehyd PF16363.5 KLO15542.1 - 1.9e-156 520.6 0.0 2.2e-156 520.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KLO15542.1 - 5.2e-72 242.2 0.0 7.2e-72 241.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KLO15542.1 - 0.00044 19.5 0.0 0.001 18.2 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KLO15542.1 - 0.0021 17.3 0.0 0.0073 15.5 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GXGXG PF01493.19 KLO15542.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 GXGXG motif TPT PF03151.16 KLO15543.1 - 1.3e-16 60.8 27.7 1.7e-16 60.4 27.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KLO15543.1 - 0.00079 19.6 44.0 0.014 15.5 16.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family PAPS_reduct PF01507.19 KLO15544.1 - 2.2e-27 96.2 0.0 5.8e-27 94.8 0.0 1.6 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SPOB_ab PF14682.6 KLO15544.1 - 0.0054 16.8 0.0 0.0092 16.1 0.0 1.3 1 0 0 1 1 1 1 Sporulation initiation phospho-transferase B, C-terminal Pkinase PF00069.25 KLO15545.1 - 2.9e-17 62.9 0.0 1.3e-16 60.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KLO15545.1 - 4.9e-13 49.3 14.0 3.1e-07 31.0 0.5 6.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 KLO15545.1 - 2.5e-09 36.8 0.0 3.1e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KLO15545.1 - 8.6e-08 31.8 8.1 0.018 15.2 0.1 5.2 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 KLO15545.1 - 1.7e-05 25.1 0.1 0.018 15.4 0.3 3.5 2 2 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KLO15545.1 - 0.066 13.2 2.5 5 7.1 0.2 2.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 BLM10_N PF16547.5 KLO15546.1 - 0.045 14.0 0.7 0.12 12.6 0.7 1.7 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Promethin PF16015.5 KLO15547.1 - 5.1e-11 42.4 16.2 6.8e-11 42.0 16.2 1.1 1 0 0 1 1 1 1 Promethin ArfGap PF01412.18 KLO15548.1 - 1.4e-41 141.2 0.7 2.4e-41 140.5 0.7 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UcrQ PF02939.16 KLO15549.1 - 1.5e-28 98.5 0.9 1.8e-28 98.3 0.9 1.1 1 0 0 1 1 1 1 UcrQ family HSP20 PF00011.21 KLO15550.1 - 3.7e-15 55.9 0.0 4.2e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KLO15550.1 - 8e-09 34.9 0.0 1.2e-08 34.3 0.0 1.3 1 1 0 1 1 1 1 HSP20-like domain found in ArsA zf-RING_UBOX PF13445.6 KLO15551.1 - 1.2e-07 31.6 2.5 4.3e-07 29.8 2.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KLO15551.1 - 1.3e-07 31.3 0.3 1.3e-07 31.3 0.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO15551.1 - 3.7e-07 29.9 1.7 3.7e-07 29.9 1.7 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO15551.1 - 6e-06 26.5 2.2 6e-06 26.5 2.2 3.0 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.6 KLO15551.1 - 1.6e-05 24.7 13.0 0.00026 20.8 0.6 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KLO15551.1 - 0.00011 22.3 4.3 0.00011 22.3 4.3 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KLO15551.1 - 0.00031 20.6 4.6 0.00031 20.6 4.6 2.7 2 1 0 2 2 2 1 zinc-RING finger domain IBR PF01485.21 KLO15551.1 - 1.3 9.3 5.0 3.6 7.9 0.8 3.0 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain zf-MIZ PF02891.20 KLO15551.1 - 4.9 7.0 7.5 0.31 10.8 2.1 1.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger RNA_pol_A_bac PF01000.26 KLO15553.1 - 1.6e-26 92.9 0.0 2.8e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KLO15553.1 - 3.6e-16 58.3 0.0 6.5e-16 57.5 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.32 KLO15554.1 - 2.7e-24 84.9 18.9 6.9e-06 26.7 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO15554.1 - 2.1e-14 53.6 0.0 0.026 14.8 0.0 5.6 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KLO15554.1 - 3.6e-10 40.0 1.1 7.1e-09 35.8 0.2 2.8 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KLO15554.1 - 1.9e-05 25.1 0.2 1.9e-05 25.1 0.2 1.9 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KLO15554.1 - 0.011 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 KLO15554.1 - 0.022 15.2 0.0 0.074 13.5 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TruB_C_2 PF16198.5 KLO15554.1 - 0.06 13.5 0.3 0.83 9.9 0.4 2.6 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain CSTF2_hinge PF14327.6 KLO15555.1 - 2.1e-28 98.6 1.4 2.1e-28 98.6 1.4 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KLO15555.1 - 3.3e-21 74.9 0.0 5e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KLO15555.1 - 7.3e-15 54.3 4.9 1.7e-14 53.1 4.9 1.7 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KLO15555.1 - 0.00084 19.4 0.0 0.0028 17.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif DUF3106 PF11304.8 KLO15555.1 - 0.066 13.7 0.1 0.71 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) SNF5 PF04855.12 KLO15556.1 - 6.5e-61 206.2 2.1 9e-61 205.7 0.7 1.9 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KLO15556.1 - 0.2 11.3 5.2 0.4 10.3 5.2 1.5 1 0 0 1 1 1 0 GATA zinc finger K_channel_TID PF07941.11 KLO15557.1 - 0.016 15.6 2.2 0.016 15.6 2.2 2.8 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain TMEM132D_C PF15706.5 KLO15557.1 - 0.6 9.9 2.4 2 8.2 2.4 1.8 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term F-box PF00646.33 KLO15558.1 - 3.7e-08 33.0 2.0 3.7e-08 33.0 2.0 2.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KLO15558.1 - 6.3e-08 32.4 0.5 6.3e-08 32.4 0.5 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO15559.1 - 2.9e-06 27.0 0.4 8.4e-06 25.5 0.4 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO15559.1 - 7.6e-06 25.7 0.2 1.7e-05 24.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like Dsl1_N PF11988.8 KLO15560.1 - 0.051 12.6 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal RNA_POL_M_15KD PF02150.16 KLO15560.1 - 0.39 10.6 6.5 1.4 8.9 6.5 2.0 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit F-box PF00646.33 KLO15561.1 - 1.7e-06 27.7 1.8 4.5e-06 26.4 1.8 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO15561.1 - 0.0014 18.4 0.6 0.0014 18.4 0.6 2.5 2 0 0 2 2 2 1 F-box-like VMA21 PF09446.10 KLO15562.1 - 0.21 11.7 0.1 0.33 11.1 0.1 1.3 1 0 0 1 1 1 0 VMA21-like domain LtrA PF06772.11 KLO15564.1 - 9.9e-38 130.3 2.2 1.9e-37 129.3 0.8 2.1 2 1 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) DUF1980 PF09323.10 KLO15564.1 - 0.16 11.9 0.6 4 7.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4125 PF13526.6 KLO15565.1 - 0.027 14.1 0.1 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) Fib_alpha PF08702.10 KLO15565.1 - 0.14 12.3 1.4 0.47 10.6 1.4 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family p450 PF00067.22 KLO15569.1 - 2.9e-60 204.3 0.0 7.7e-60 202.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 ACOX PF01756.19 KLO15570.1 - 3.6e-33 114.6 0.1 7.6e-33 113.6 0.1 1.5 1 1 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KLO15570.1 - 9.7e-13 48.8 0.0 1.9e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KLO15570.1 - 5.3e-08 32.9 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KLO15570.1 - 0.00019 21.7 0.1 0.00042 20.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TPP_enzyme_N PF02776.18 KLO15571.1 - 2.6e-34 118.3 0.0 5e-33 114.1 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KLO15571.1 - 8.5e-20 71.1 0.1 1.5e-19 70.3 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KLO15571.1 - 1.6e-08 34.4 0.0 9.6e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain XFP_N PF09364.10 KLO15571.1 - 0.0036 16.2 0.1 0.0052 15.6 0.1 1.1 1 0 0 1 1 1 1 XFP N-terminal domain F-box-like PF12937.7 KLO15572.1 - 2.4e-05 24.1 0.1 7.2e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KLO15572.1 - 0.043 13.4 0.4 0.14 11.7 0.2 1.9 2 0 0 2 2 2 0 F-box F-box PF00646.33 KLO15572.1 - 0.062 13.2 1.0 0.26 11.2 0.0 2.6 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.7 KLO15572.1 - 2.8 8.5 6.7 8 7.0 0.6 3.6 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO15573.1 - 0.006 16.4 2.4 0.0098 15.8 0.2 2.6 3 0 0 3 3 3 1 F-box-like Tropomyosin_1 PF12718.7 KLO15574.1 - 0.11 12.7 13.2 0.031 14.4 0.5 2.6 1 1 1 2 2 2 0 Tropomyosin like AAA_13 PF13166.6 KLO15574.1 - 0.13 10.9 13.1 0.24 10.0 13.1 1.3 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 KLO15574.1 - 0.16 12.0 0.5 6.3 6.8 0.1 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1640 PF07798.11 KLO15574.1 - 9.7 6.2 12.5 0.059 13.4 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Pyr_redox_3 PF13738.6 KLO15576.1 - 3.8e-21 75.6 0.0 2.7e-18 66.3 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KLO15576.1 - 6e-20 71.1 0.0 3.3e-18 65.4 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KLO15576.1 - 3.9e-12 46.0 0.0 2.4e-08 33.5 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KLO15576.1 - 1.6e-11 44.0 0.1 5.3e-08 32.5 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO15576.1 - 1e-07 32.4 0.1 0.027 15.0 0.1 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KLO15576.1 - 0.00012 21.5 0.0 0.045 13.1 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KLO15576.1 - 0.0045 16.6 0.0 1 8.9 0.0 2.8 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO15576.1 - 0.0064 16.7 0.0 0.062 13.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KLO15576.1 - 0.0081 15.3 0.0 0.029 13.5 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KLO15576.1 - 0.0085 15.4 0.2 0.019 14.2 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KLO15576.1 - 0.034 13.2 0.0 2.9 6.9 0.1 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 KLO15576.1 - 0.11 11.5 0.1 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KLO15576.1 - 0.17 11.8 0.1 0.93 9.3 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 KLO15577.1 - 1e-55 189.2 0.0 1.3e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO15577.1 - 7.5e-33 114.1 0.1 1.2e-32 113.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KLO15577.1 - 2.5e-06 27.6 0.3 0.00053 20.2 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO15577.1 - 0.0003 20.5 0.1 0.00058 19.5 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KLO15577.1 - 0.00072 18.7 0.1 0.0012 18.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KLO15577.1 - 0.0049 16.0 0.2 0.0084 15.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KLO15577.1 - 0.0071 15.6 0.1 0.025 13.8 0.1 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KLO15577.1 - 0.0099 14.6 0.1 0.067 11.9 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KLO15577.1 - 0.012 14.9 0.9 0.036 13.3 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KLO15577.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KLO15577.1 - 0.089 12.8 0.0 0.49 10.4 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding HTH_32 PF13565.6 KLO15581.1 - 0.00026 21.6 0.0 0.00028 21.5 0.0 1.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KLO15581.1 - 0.0057 16.6 0.1 0.0065 16.5 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn helix DDE_3 PF13358.6 KLO15582.1 - 1e-09 38.3 0.0 1.2e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KLO15583.1 - 4.7e-08 32.9 0.0 9.9e-08 31.9 0.0 1.6 1 1 1 2 2 2 1 DDE superfamily endonuclease Peripla_BP_1 PF00532.21 KLO15584.1 - 0.025 14.0 0.2 0.068 12.6 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family DUF4685 PF15737.5 KLO15584.1 - 0.054 13.9 0.8 0.13 12.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) F-box-like PF12937.7 KLO15586.1 - 1.8e-07 30.9 1.1 3.6e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO15586.1 - 0.036 14.0 0.1 0.28 11.1 0.1 2.4 1 1 0 1 1 1 0 F-box domain NIR_SIR_ferr PF03460.17 KLO15586.1 - 0.16 11.8 0.0 0.91 9.4 0.0 2.1 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain Lipase_GDSL_2 PF13472.6 KLO15587.1 - 2.8e-10 40.9 0.9 5.6e-10 39.9 0.9 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KLO15587.1 - 2.4e-08 34.2 0.1 1.1e-07 32.0 0.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CE2_N PF17996.1 KLO15587.1 - 0.0022 18.0 0.0 0.0072 16.3 0.0 1.9 1 1 0 1 1 1 1 Carbohydrate esterase 2 N-terminal UBN_AB PF14075.6 KLO15589.1 - 9.5e-41 139.9 0.4 2.8e-40 138.3 0.0 1.9 2 0 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 KLO15589.1 - 2e-13 50.1 0.0 4.7e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Velvet PF11754.8 KLO15593.1 - 6.1e-39 134.5 0.3 5.6e-21 75.6 0.1 6.1 2 2 2 4 4 4 2 Velvet factor DUF4632 PF15451.6 KLO15593.1 - 0.9 9.7 4.9 2.5 8.3 4.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) MFS_1 PF07690.16 KLO15595.1 - 1.1e-22 80.4 21.0 1.7e-22 79.8 21.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily La PF05383.17 KLO15596.1 - 4.8e-22 77.8 0.0 1e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KLO15596.1 - 2e-05 24.3 0.2 7.6e-05 22.5 0.2 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KLO15596.1 - 8.4e-05 22.6 0.4 0.00072 19.6 0.1 2.5 2 0 0 2 2 2 1 RNA binding motif DarA_C PF18789.1 KLO15596.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Defence against restriction A C-terminal AMP-binding PF00501.28 KLO15597.1 - 3.5e-92 309.2 0.1 4.7e-92 308.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KLO15597.1 - 0.00021 22.2 0.0 0.0011 19.9 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.6 KLO15598.1 - 7.8e-12 45.3 0.0 4.1e-11 43.0 0.0 2.0 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO15598.1 - 2.4e-09 37.8 0.0 8.6e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO15598.1 - 5.1e-09 36.7 0.0 1.3e-08 35.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO15598.1 - 6.7e-08 32.5 0.0 3.9e-07 30.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO15598.1 - 2.3e-05 25.1 0.0 5.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KLO15598.1 - 0.0012 18.3 0.0 0.0037 16.7 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 KLO15598.1 - 0.059 12.7 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain DOT1 PF08123.13 KLO15598.1 - 0.063 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 KLO15598.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DNA_pol_lambd_f PF10391.9 KLO15599.1 - 3.6e-21 74.7 0.2 4.7e-19 67.9 0.1 3.0 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KLO15599.1 - 1.4e-19 70.0 0.1 3.2e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KLO15599.1 - 1.8e-18 66.7 0.3 2.4e-17 63.0 0.1 2.7 3 0 0 3 3 3 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.6 KLO15599.1 - 1.8e-15 57.1 0.0 3.6e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_5 PF14520.6 KLO15599.1 - 6e-06 26.8 0.1 0.32 11.6 0.1 3.6 3 1 0 3 3 3 2 Helix-hairpin-helix domain HHH PF00633.23 KLO15599.1 - 0.00047 19.9 1.1 0.069 13.1 0.1 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 KLO15599.1 - 0.011 16.4 0.2 2.7 8.7 0.1 2.8 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Cdd1 PF11731.8 KLO15599.1 - 0.018 15.3 0.0 2 8.7 0.0 3.9 3 1 2 5 5 5 0 Pathogenicity locus DUF3701 PF12482.8 KLO15599.1 - 0.042 13.9 0.0 4.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Phage integrase protein HHH_2 PF12826.7 KLO15599.1 - 0.1 12.7 0.1 2.7 8.2 0.1 2.8 2 1 1 3 3 3 0 Helix-hairpin-helix motif Peptidase_M16 PF00675.20 KLO15600.1 - 5.2e-23 81.7 0.0 1.3e-22 80.4 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KLO15600.1 - 4.9e-05 23.4 0.0 0.00018 21.6 0.0 2.0 1 1 0 1 1 1 1 Peptidase M16 inactive domain Pheromone PF08015.11 KLO15601.1 - 0.058 14.4 1.7 0.058 14.4 1.7 5.9 3 1 1 4 4 4 0 Fungal mating-type pheromone ARS2 PF04959.13 KLO15601.1 - 0.088 13.2 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 F-box PF00646.33 KLO15603.1 - 5.1e-05 23.0 1.1 0.00018 21.3 1.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO15603.1 - 0.0075 16.1 0.8 0.027 14.4 0.8 2.0 1 0 0 1 1 1 1 F-box-like Utp14 PF04615.13 KLO15606.1 - 0.0031 16.2 3.9 0.0042 15.7 3.9 1.1 1 0 0 1 1 1 1 Utp14 protein DUF4448 PF14610.6 KLO15606.1 - 0.0067 16.2 0.4 0.017 14.9 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Tim54 PF11711.8 KLO15606.1 - 0.0096 14.7 0.3 0.018 13.8 0.3 1.4 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Mid2 PF04478.12 KLO15606.1 - 0.027 14.3 0.4 0.027 14.3 0.4 2.4 2 1 1 3 3 3 0 Mid2 like cell wall stress sensor LAP1C PF05609.12 KLO15606.1 - 0.032 13.4 9.6 0.042 12.9 9.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF5305 PF17231.2 KLO15606.1 - 0.084 12.3 0.2 0.17 11.3 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SURF2 PF05477.11 KLO15606.1 - 0.33 10.6 7.2 0.5 10.0 7.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SKG6 PF08693.10 KLO15606.1 - 0.43 10.0 2.7 0.63 9.5 0.0 2.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain NPR3 PF03666.13 KLO15606.1 - 1.3 7.7 15.3 1.8 7.2 15.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM76 PF16046.5 KLO15606.1 - 7.9 5.7 11.8 12 5.1 11.8 1.2 1 0 0 1 1 1 0 FAM76 protein Adaptin_N PF01602.20 KLO15607.1 - 5e-142 474.1 5.4 6.4e-142 473.8 5.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KLO15607.1 - 3.2e-60 202.9 4.5 3.4e-59 199.5 0.6 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KLO15607.1 - 1e-18 67.5 3.6 2.1e-06 28.1 0.0 6.2 2 2 4 6 6 6 4 HEAT repeats HEAT PF02985.22 KLO15607.1 - 5.2e-13 48.0 3.3 0.00014 21.8 0.1 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 KLO15607.1 - 7e-05 23.2 3.5 1.9 9.1 0.1 6.1 6 1 1 7 7 7 1 HEAT-like repeat RTP1_C1 PF10363.9 KLO15607.1 - 0.0002 21.5 1.0 0.46 10.7 0.0 4.4 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KLO15607.1 - 0.001 18.7 0.1 0.33 10.5 0.0 3.3 2 1 1 3 3 3 1 CLASP N terminal Arm PF00514.23 KLO15607.1 - 0.018 15.1 4.8 13 6.0 0.0 5.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 KLO15607.1 - 0.037 13.2 0.2 5.6 6.1 0.0 2.6 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain GMC_oxred_N PF00732.19 KLO15608.1 - 1.8e-54 185.1 0.0 2.3e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO15608.1 - 9.4e-32 110.5 0.0 1.5e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KLO15608.1 - 2.1e-06 27.9 0.4 8.2e-05 22.8 0.7 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO15608.1 - 0.00015 21.4 0.1 0.00061 19.5 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO15608.1 - 0.00029 20.1 0.7 0.013 14.6 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KLO15608.1 - 0.00051 19.2 0.0 0.00083 18.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KLO15608.1 - 0.0021 16.8 0.0 0.044 12.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KLO15608.1 - 0.0054 16.0 0.0 0.033 13.4 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO15608.1 - 0.0061 15.8 0.4 0.065 12.5 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO15608.1 - 0.032 13.5 0.1 0.067 12.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KLO15608.1 - 0.058 14.0 0.0 0.62 10.7 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KLO15608.1 - 0.068 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KLO15608.1 - 0.14 12.5 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain K_oxygenase PF13434.6 KLO15608.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KLO15608.1 - 0.2 10.9 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GMC_oxred_N PF00732.19 KLO15610.1 - 1.5e-65 221.5 0.0 1.9e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO15610.1 - 7.3e-35 120.6 0.0 1.2e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KLO15610.1 - 0.0016 17.6 0.3 0.19 10.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KLO15610.1 - 0.0052 15.9 0.1 0.0081 15.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KLO15610.1 - 0.0098 16.1 0.1 0.025 14.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO15610.1 - 0.014 14.7 0.1 0.031 13.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO15610.1 - 0.05 13.2 0.2 0.21 11.1 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KLO15610.1 - 0.051 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 KLO15610.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KLO15610.1 - 0.14 10.9 0.1 0.26 9.9 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KLO15610.1 - 0.16 10.7 0.2 0.34 9.7 0.2 1.5 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_N PF00732.19 KLO15613.1 - 1.9e-60 204.8 0.0 2.5e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO15613.1 - 2.6e-35 122.1 0.0 4.1e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KLO15614.1 - 4.2e-65 220.0 0.0 5.2e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO15614.1 - 8.8e-37 126.8 0.0 1.3e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KLO15614.1 - 0.0022 17.1 1.2 0.13 11.3 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KLO15614.1 - 0.0029 17.8 0.0 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KLO15614.1 - 0.0045 16.1 0.2 0.0076 15.3 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KLO15614.1 - 0.0048 16.2 0.1 0.0099 15.1 0.1 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KLO15614.1 - 0.0081 15.8 1.1 0.034 13.7 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO15614.1 - 0.019 14.2 0.1 0.045 13.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KLO15614.1 - 0.063 12.6 1.4 5.3 6.3 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase p450 PF00067.22 KLO15615.1 - 1.5e-50 172.3 0.0 2.5e-49 168.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KLO15617.1 - 0.00022 21.1 1.2 0.001 18.9 0.4 2.7 3 0 0 3 3 3 1 F-box-like DEAD PF00270.29 KLO15618.1 - 3.4e-07 30.2 0.0 3.9e-06 26.7 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO15618.1 - 3.9e-06 27.2 0.0 1.8e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.14 KLO15618.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain p450 PF00067.22 KLO15619.1 - 7.8e-56 189.7 0.0 9.8e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 KLO15620.1 - 1.1e-24 87.1 9.9 1.5e-24 86.7 9.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family F-box-like PF12937.7 KLO15621.1 - 0.00071 19.4 0.1 0.0025 17.7 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO15622.1 - 4.5e-06 26.5 0.2 1.6e-05 24.7 0.2 2.0 2 0 0 2 2 2 1 F-box-like NOA36 PF06524.12 KLO15622.1 - 0.12 11.7 14.5 0.21 10.9 14.5 1.4 1 0 0 1 1 1 0 NOA36 protein p450 PF00067.22 KLO15623.1 - 3.8e-68 230.3 0.0 4.8e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO15624.1 - 3.6e-53 180.9 0.0 4.3e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PGG PF13962.6 KLO15625.1 - 2.1 8.2 9.5 0.15 11.8 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function UbiA PF01040.18 KLO15626.1 - 1.2e-23 83.7 8.4 1.2e-23 83.7 8.4 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family F-box-like PF12937.7 KLO15628.1 - 9.2e-09 35.1 0.1 2.5e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO15629.1 - 3.7e-09 36.3 0.9 1.6e-07 31.1 0.1 2.5 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KLO15629.1 - 0.0099 15.7 0.1 0.13 12.1 0.0 2.7 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 KLO15630.1 - 7e-07 29.0 1.8 1.5e-05 24.8 0.3 2.6 2 0 0 2 2 2 2 F-box-like F-box-like PF12937.7 KLO15631.1 - 5.3e-08 32.6 0.1 2.2e-07 30.7 0.1 2.1 1 0 0 1 1 1 1 F-box-like PAP2_3 PF14378.6 KLO15633.1 - 1.8e-44 151.7 13.6 1.8e-44 151.7 13.6 1.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KLO15633.1 - 0.00038 20.9 2.8 0.00038 20.9 2.8 2.4 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 KLO15633.1 - 0.0087 15.8 3.7 0.0087 15.8 3.7 2.5 1 1 0 2 2 2 1 PAP2 superfamily Tektin PF03148.14 KLO15636.1 - 2.9e-06 26.3 0.1 2.9e-06 26.3 0.1 1.8 2 0 0 2 2 2 1 Tektin family DUF3294 PF07957.11 KLO15636.1 - 0.009 15.8 0.0 0.019 14.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3294) HALZ PF02183.18 KLO15636.1 - 0.021 15.0 0.8 0.41 10.9 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper UPF0242 PF06785.11 KLO15636.1 - 0.054 13.6 2.7 0.56 10.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KLO15636.1 - 0.085 11.7 5.3 0.76 8.6 0.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Cortex-I_coil PF09304.10 KLO15636.1 - 0.094 12.9 8.0 1.8 8.8 0.3 2.7 3 0 0 3 3 3 0 Cortexillin I, coiled coil PLAC9 PF15205.6 KLO15636.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Placenta-specific protein 9 DUF1664 PF07889.12 KLO15636.1 - 0.12 12.5 2.4 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 KLO15636.1 - 0.13 12.5 5.9 0.3 11.2 0.5 2.2 2 0 0 2 2 2 0 Tropomyosin like MscS_porin PF12795.7 KLO15636.1 - 0.17 11.4 12.1 0.041 13.4 1.1 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain GCN5L1 PF06320.13 KLO15636.1 - 0.22 11.7 2.7 0.35 11.0 0.1 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) FlaC_arch PF05377.11 KLO15636.1 - 0.3 11.5 1.8 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3338 PF11819.8 KLO15636.1 - 0.39 10.7 0.1 0.39 10.7 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3338) ZapB PF06005.12 KLO15636.1 - 0.53 10.8 7.5 1.4 9.4 1.5 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Occludin_ELL PF07303.13 KLO15636.1 - 0.58 10.9 2.7 11 6.8 0.2 2.5 2 0 0 2 2 2 0 Occludin homology domain bZIP_1 PF00170.21 KLO15636.1 - 0.61 10.2 4.0 3.7 7.7 0.1 2.7 3 0 0 3 3 3 0 bZIP transcription factor EzrA PF06160.12 KLO15636.1 - 0.62 8.2 3.7 0.15 10.2 0.2 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA GAS PF13851.6 KLO15636.1 - 0.9 8.9 6.0 0.2 11.0 0.8 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 KLO15636.1 - 0.9 9.9 7.5 4.9 7.6 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) OmpH PF03938.14 KLO15636.1 - 0.93 9.8 9.7 0.6 10.5 0.8 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 KLO15636.1 - 1.2 9.7 9.3 0.087 13.4 1.8 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DHR10 PF18595.1 KLO15636.1 - 1.4 9.0 10.2 0.31 11.1 1.4 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain CLZ PF16526.5 KLO15636.1 - 1.6 9.2 6.5 1.2 9.6 0.6 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc24 PF08286.11 KLO15636.1 - 1.6 9.0 3.9 2.4 8.4 0.5 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.15 KLO15636.1 - 4.5 7.4 8.5 5.3 7.2 2.4 2.4 2 0 0 2 2 2 0 Basic region leucine zipper EMP24_GP25L PF01105.24 KLO15636.1 - 8.1 6.3 7.9 8.1 6.3 2.3 2.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD F-box-like PF12937.7 KLO15637.1 - 5.3e-05 23.0 1.3 0.00012 21.8 0.1 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO15637.1 - 0.094 12.6 0.3 0.72 9.8 0.1 2.7 2 1 0 2 2 2 0 F-box domain DUF4703 PF15775.5 KLO15639.1 - 0.25 11.1 3.8 0.36 10.6 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) BOP1NT PF08145.12 KLO15640.1 - 6.4e-101 337.6 7.3 8.6e-101 337.2 7.3 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KLO15640.1 - 3.3e-20 72.0 13.7 6.8e-06 26.7 0.4 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO15640.1 - 6.9e-07 29.5 0.8 0.24 11.7 0.1 5.1 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain SDA1 PF05285.12 KLO15640.1 - 0.95 8.8 12.3 1.6 8.1 12.3 1.4 1 0 0 1 1 1 0 SDA1 Actin PF00022.19 KLO15641.1 - 4.2e-118 394.5 0.0 4.8e-118 394.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KLO15641.1 - 8.2e-05 21.6 0.0 0.055 12.3 0.0 2.4 2 1 0 2 2 2 2 MreB/Mbl protein DUF2423 PF10338.9 KLO15643.1 - 3.3e-14 52.8 4.5 6.4e-14 51.9 4.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Laps PF10169.9 KLO15643.1 - 0.00017 22.1 8.5 0.00023 21.8 8.5 1.2 1 0 0 1 1 1 1 Learning-associated protein DUF3367 PF11847.8 KLO15643.1 - 0.15 9.9 0.5 0.17 9.7 0.5 1.0 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase p450 PF00067.22 KLO15646.1 - 6.3e-68 229.6 0.0 8.5e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO15647.1 - 6.8e-67 226.2 0.0 9.1e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO15649.1 - 5e-59 200.3 0.0 6.7e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glucos_trans_II PF14264.6 KLO15649.1 - 0.1 11.9 4.0 0.16 11.3 4.0 1.2 1 0 0 1 1 1 0 Glucosyl transferase GtrII Ribosomal_L19 PF01245.20 KLO15650.1 - 3e-16 59.3 0.1 4.8e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 IMD PF08397.11 KLO15651.1 - 0.00014 21.3 1.6 0.00023 20.6 1.6 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain BAR_3 PF16746.5 KLO15651.1 - 0.0017 18.2 2.6 0.0029 17.4 2.6 1.4 1 0 0 1 1 1 1 BAR domain of APPL family DUF3150 PF11348.8 KLO15651.1 - 0.0049 16.1 0.7 0.0078 15.5 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3150) ARD PF03079.14 KLO15651.1 - 0.0089 16.2 1.0 0.015 15.5 1.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family D5_N PF08706.11 KLO15651.1 - 0.056 13.7 0.3 0.13 12.5 0.1 1.7 2 0 0 2 2 2 0 D5 N terminal like HAUS6_N PF14661.6 KLO15651.1 - 0.14 11.7 1.7 0.24 10.9 1.7 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus tRNA-synt_2 PF00152.20 KLO15655.1 - 2.8e-85 286.1 0.0 2.4e-84 283.1 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KLO15655.1 - 3.5e-06 26.9 0.0 7.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ACPS PF01648.20 KLO15657.1 - 3.1e-11 43.4 0.0 6.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PfkB PF00294.24 KLO15659.1 - 1.4e-15 57.4 0.0 1.9e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KLO15659.1 - 0.0057 16.1 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase CBFD_NFYB_HMF PF00808.23 KLO15660.1 - 3.2e-21 75.4 0.5 5.1e-21 74.7 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KLO15660.1 - 0.015 15.6 0.7 0.033 14.5 0.1 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 LSM PF01423.22 KLO15661.1 - 2.3e-21 75.3 0.0 2.7e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KLO15661.1 - 0.00086 19.4 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain RNA_POL_M_15KD PF02150.16 KLO15661.1 - 0.075 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit RRM_1 PF00076.22 KLO15662.1 - 7.1e-15 54.6 0.0 1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KLO15662.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SIR2 PF02146.17 KLO15663.1 - 3.2e-32 111.9 0.1 9.4e-30 103.8 0.1 3.2 1 1 0 1 1 1 1 Sir2 family PNTB PF02233.16 KLO15663.1 - 0.0025 16.8 0.1 0.068 12.1 0.0 2.0 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 KLO15663.1 - 0.0061 16.3 0.0 0.071 12.9 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fungal_trans PF04082.18 KLO15664.1 - 2.2e-28 99.1 0.0 3.2e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO15664.1 - 3.8e-09 36.5 11.4 1.1e-08 35.1 11.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBV_3C PF03620.13 KLO15664.1 - 0.023 15.2 0.3 0.055 14.0 0.3 1.6 1 0 0 1 1 1 0 IBV 3C protein Acyl-CoA_dh_1 PF00441.24 KLO15665.1 - 1e-28 100.4 1.1 1.7e-28 99.7 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KLO15665.1 - 5e-20 71.5 0.0 1.4e-19 70.1 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KLO15665.1 - 8.7e-12 45.5 1.0 1.5e-11 44.7 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KLO15665.1 - 2.4e-11 44.3 0.0 5.6e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain p450 PF00067.22 KLO15666.1 - 1.9e-67 228.0 0.0 2.2e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Inhibitor_I10 PF12559.8 KLO15666.1 - 0.0044 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Serine endopeptidase inhibitors baeRF_family10 PF18854.1 KLO15666.1 - 0.076 13.3 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 Aldedh PF00171.22 KLO15667.1 - 1.1e-82 278.0 0.0 1.4e-82 277.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ACT_7 PF13840.6 KLO15667.1 - 0.091 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 ACT domain Peptidase_M24 PF00557.24 KLO15668.1 - 1.6e-12 47.6 0.0 2.2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 GTP_cyclohydro2 PF00925.20 KLO15669.1 - 1e-60 204.1 0.0 1.5e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II LAP1C PF05609.12 KLO15671.1 - 0.00084 18.5 0.5 0.0011 18.2 0.5 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 KLO15671.1 - 0.015 13.6 4.1 0.02 13.1 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KLO15671.1 - 0.034 12.5 2.7 0.049 11.9 2.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 KLO15671.1 - 0.053 12.1 2.6 0.056 12.0 2.6 1.1 1 0 0 1 1 1 0 Macoilin family Roughex PF06020.11 KLO15671.1 - 0.14 11.2 6.4 0.21 10.6 6.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein SDA1 PF05285.12 KLO15671.1 - 0.16 11.3 6.2 0.25 10.8 6.2 1.3 1 0 0 1 1 1 0 SDA1 DUF3545 PF12065.8 KLO15671.1 - 0.17 12.0 0.6 0.33 11.0 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) GP67 PF17634.2 KLO15671.1 - 0.22 11.9 8.9 0.39 11.1 8.9 1.4 1 0 0 1 1 1 0 Gene product 67 DNA_pol_phi PF04931.13 KLO15671.1 - 2.1 6.3 8.7 2.6 6.0 8.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 KLO15671.1 - 3.1 5.8 13.6 3.9 5.4 13.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GREB1 PF15782.5 KLO15671.1 - 3.1 4.8 6.6 3.8 4.5 6.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 KLO15671.1 - 5.9 5.6 6.3 12 4.6 6.3 1.5 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.12 KLO15671.1 - 9.8 4.6 17.2 15 4.1 17.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Complex1_LYR_2 PF13233.6 KLO15672.1 - 5.1e-16 59.2 1.0 6.5e-16 58.9 1.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like XendoU PF09412.10 KLO15672.1 - 0.049 12.9 0.1 0.057 12.6 0.1 1.0 1 0 0 1 1 1 0 Endoribonuclease XendoU SIR2 PF02146.17 KLO15673.1 - 5.4e-32 111.1 0.4 3.1e-29 102.1 0.4 3.2 1 1 0 1 1 1 1 Sir2 family PNTB PF02233.16 KLO15673.1 - 7e-05 21.9 0.0 0.092 11.6 0.0 2.1 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 KLO15673.1 - 0.00033 20.4 0.0 0.0095 15.7 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain MRP-S26 PF14943.6 KLO15674.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 FAD_binding_3 PF01494.19 KLO15675.1 - 1e-08 34.8 0.6 1.4e-07 31.1 0.4 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KLO15675.1 - 0.097 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase RasGAP_C PF03836.15 KLO15676.1 - 6.2e-46 156.0 3.2 6.2e-46 156.0 3.2 2.9 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.19 KLO15676.1 - 5.9e-39 133.9 0.1 1.7e-38 132.4 0.1 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 KLO15676.1 - 7.3e-18 62.6 63.4 0.0051 16.5 2.1 13.7 13 0 0 13 13 13 12 IQ calmodulin-binding motif CH PF00307.31 KLO15676.1 - 1.1e-11 44.8 0.0 3.3e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain NPV_P10 PF05531.12 KLO15676.1 - 1.4 9.4 5.3 2.5 8.6 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.16 KLO15677.1 - 1.9e-32 112.6 17.4 1.9e-32 112.6 17.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 KLO15677.1 - 0.076 13.3 0.2 0.076 13.3 0.2 4.1 4 1 0 4 4 4 0 Phage holin family Hol44, in holin superfamily V OppC_N PF12911.7 KLO15678.1 - 0.11 12.5 0.3 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF4614 PF15391.6 KLO15678.1 - 0.28 11.2 30.6 0.74 9.8 30.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Utp14 PF04615.13 KLO15678.1 - 0.35 9.4 9.8 0.51 8.9 9.8 1.2 1 0 0 1 1 1 0 Utp14 protein SLC12 PF03522.15 KLO15678.1 - 0.48 9.4 6.8 0.7 8.8 6.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SOG2 PF10428.9 KLO15678.1 - 0.56 9.3 41.5 0.011 15.0 30.1 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Macoilin PF09726.9 KLO15678.1 - 0.77 8.2 22.1 1.2 7.6 22.1 1.3 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 KLO15678.1 - 0.84 8.3 13.4 2 7.1 13.4 1.6 1 0 0 1 1 1 0 Presenilin PPP4R2 PF09184.11 KLO15678.1 - 1 8.9 14.4 1.6 8.2 14.4 1.3 1 0 0 1 1 1 0 PPP4R2 Comm PF15957.5 KLO15678.1 - 1.9 8.8 0.0 1.9 8.8 0.0 3.1 3 1 0 3 3 1 0 Commissureless Smg8_Smg9 PF10220.9 KLO15678.1 - 2.8 6.1 11.0 4.1 5.6 11.0 1.2 1 0 0 1 1 1 0 Smg8_Smg9 GREB1 PF15782.5 KLO15678.1 - 3 4.9 15.9 4 4.4 15.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4551 PF15087.6 KLO15678.1 - 5.6 5.7 11.4 9 5.0 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Aldedh PF00171.22 KLO15679.1 - 2.2e-144 481.4 0.0 2.6e-144 481.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KLO15679.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) OKR_DC_1_N PF03709.15 KLO15679.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain ComA PF02679.15 KLO15680.1 - 1.4e-76 257.1 0.0 1.8e-76 256.8 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) PEP_mutase PF13714.6 KLO15680.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase SinI PF08671.10 KLO15680.1 - 0.026 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Anti-repressor SinI UTP15_C PF09384.10 KLO15682.1 - 1.6e-49 167.3 0.3 2.5e-49 166.8 0.3 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KLO15682.1 - 5.6e-25 87.1 3.6 0.00021 22.0 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO15682.1 - 7.2e-09 35.8 0.0 0.014 15.6 0.0 5.1 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KLO15682.1 - 0.00075 18.1 0.1 0.027 13.0 0.0 2.6 2 1 1 3 3 3 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 KLO15682.1 - 0.07 12.2 0.0 3.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region ATAD4 PF15321.6 KLO15682.1 - 0.13 13.7 0.0 0.33 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 PQQ_3 PF13570.6 KLO15682.1 - 1.2 9.7 3.2 18 6.0 0.0 3.2 4 0 0 4 4 4 0 PQQ-like domain TCTP PF00838.17 KLO15683.1 - 7.6e-64 215.0 4.5 8.5e-64 214.9 4.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein CFIA_Pcf11 PF11526.8 KLO15683.1 - 0.082 13.4 1.5 0.12 12.9 1.4 1.5 1 1 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 MHYT PF03707.16 KLO15684.1 - 2.5 8.3 5.0 0.88 9.8 0.1 2.8 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat Thioredoxin PF00085.20 KLO15685.1 - 1.9e-60 201.2 0.0 4.8e-30 103.6 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KLO15685.1 - 1.8e-39 135.6 0.0 5.7e-31 107.9 0.1 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KLO15685.1 - 5.1e-07 29.8 0.1 0.0048 17.1 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KLO15685.1 - 1.6e-06 28.6 0.3 0.052 14.0 0.1 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KLO15685.1 - 2e-06 28.0 0.0 0.072 13.4 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KLO15685.1 - 4.7e-05 23.3 0.1 0.029 14.3 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Calsequestrin PF01216.17 KLO15685.1 - 4.9e-05 22.5 0.2 9.4e-05 21.6 0.2 1.5 1 0 0 1 1 1 1 Calsequestrin Redoxin PF08534.10 KLO15685.1 - 0.0014 18.3 0.4 0.7 9.6 0.1 3.1 3 0 0 3 3 3 1 Redoxin OST3_OST6 PF04756.13 KLO15685.1 - 0.0029 17.0 0.0 1.3 8.3 0.0 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 KLO15685.1 - 0.0072 16.5 0.5 1.2 9.3 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 KLO15685.1 - 0.031 14.3 0.0 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Glutaredoxin PF00462.24 KLO15685.1 - 0.23 11.7 2.3 17 5.7 0.0 3.0 2 1 0 2 2 2 0 Glutaredoxin WH2 PF02205.20 KLO15686.1 - 4.6e-07 29.4 0.8 9.2e-07 28.5 0.8 1.5 1 0 0 1 1 1 1 WH2 motif FAT PF02259.23 KLO15687.1 - 5.5e-67 226.4 4.3 1.4e-66 225.1 4.3 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KLO15687.1 - 1.5e-20 74.0 0.1 3.3e-20 72.9 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_2 PF07719.17 KLO15687.1 - 6.7e-05 22.7 0.9 0.25 11.5 0.1 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat FATC PF02260.20 KLO15687.1 - 0.0027 17.5 0.1 0.0082 15.9 0.1 1.9 1 0 0 1 1 1 1 FATC domain TPR_1 PF00515.28 KLO15687.1 - 0.0027 17.4 1.7 0.26 11.2 0.2 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KLO15687.1 - 0.019 15.1 3.1 0.025 14.8 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KLO15687.1 - 0.9 9.9 5.4 47 4.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat AA_permease_2 PF13520.6 KLO15688.1 - 1.1e-62 212.2 57.0 1.4e-62 212.0 57.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KLO15688.1 - 3.9e-15 55.4 50.3 5.3e-15 55.0 50.3 1.1 1 0 0 1 1 1 1 Amino acid permease COX7B PF05392.11 KLO15688.1 - 0.33 10.6 1.3 0.91 9.2 0.4 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB Bromodomain PF00439.25 KLO15689.1 - 1.8e-20 72.8 0.2 4.1e-20 71.6 0.2 1.6 1 0 0 1 1 1 1 Bromodomain RXLR PF16810.5 KLO15689.1 - 2 8.8 4.9 8.6 6.8 3.9 2.3 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity DUF3336 PF11815.8 KLO15690.1 - 1.3e-52 177.1 1.0 2.4e-51 173.1 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KLO15690.1 - 6e-19 69.0 0.1 1.2e-18 68.1 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase TadE PF07811.12 KLO15690.1 - 1.1 9.6 4.3 2.4 8.5 4.3 1.5 1 0 0 1 1 1 0 TadE-like protein GET2 PF08690.10 KLO15690.1 - 2.1 7.9 3.6 0.71 9.5 0.4 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 DUF262 PF03235.14 KLO15691.1 - 1.1e-15 58.4 3.2 2.1e-15 57.5 0.6 2.4 2 1 0 2 2 2 1 Protein of unknown function DUF262 CHGN PF05679.16 KLO15691.1 - 0.016 14.0 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase Asp PF00026.23 KLO15692.1 - 3.4e-95 319.1 0.0 4.1e-95 318.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO15692.1 - 1.3e-14 54.8 2.8 3.1e-12 47.1 2.6 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KLO15692.1 - 8.4e-07 29.6 0.0 0.0038 17.8 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KLO15692.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KLO15692.1 - 0.0033 18.0 0.0 1.1 9.8 0.0 2.7 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp PF00026.23 KLO15693.1 - 8.4e-107 357.2 0.0 1e-106 357.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO15693.1 - 5.5e-14 52.8 0.8 1.3e-08 35.3 0.3 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KLO15693.1 - 0.00025 20.9 0.0 0.0028 17.4 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KLO15693.1 - 0.00035 21.1 0.0 0.37 11.5 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KLO15693.1 - 0.0073 16.9 0.0 2.4 8.8 0.0 2.9 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease PUB PF09409.10 KLO15695.1 - 1.1e-11 44.4 0.4 1.4e-10 41.0 0.1 2.3 2 0 0 2 2 2 1 PUB domain TRAP-gamma PF07074.12 KLO15695.1 - 0.24 10.9 4.0 0.41 10.2 4.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Proteasome PF00227.26 KLO15696.1 - 4.4e-48 163.3 0.0 3.5e-46 157.1 0.0 2.1 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KLO15696.1 - 1.3e-12 47.2 0.1 1.3e-12 47.2 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Flavokinase PF01687.17 KLO15696.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Riboflavin kinase SMC_N PF02463.19 KLO15697.1 - 3.6e-26 92.0 0.0 3.8e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KLO15697.1 - 1.2e-05 25.3 0.8 2.3e-05 24.3 0.8 1.7 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KLO15697.1 - 0.025 15.1 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter WD40 PF00400.32 KLO15698.1 - 6.2e-14 52.2 5.9 1.7e-06 28.6 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO15698.1 - 2.1e-05 24.8 0.0 0.045 14.0 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO15698.1 - 0.17 10.8 0.0 0.67 8.9 0.0 1.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase PF00069.25 KLO15699.1 - 5.9e-72 242.2 0.0 6.9e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO15699.1 - 2.5e-35 122.0 0.0 3.1e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO15699.1 - 3e-08 33.3 0.5 2.4e-06 27.1 0.0 2.6 1 1 2 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 KLO15699.1 - 3.2e-05 23.1 0.5 0.0011 18.0 0.5 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KLO15699.1 - 6.6e-05 21.9 0.0 0.00012 21.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO15699.1 - 0.00072 19.0 1.0 0.0018 17.7 1.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PCI PF01399.27 KLO15700.1 - 2.3e-10 40.9 0.0 1.4e-09 38.4 0.0 2.4 2 0 0 2 2 2 1 PCI domain TAFH PF07531.14 KLO15700.1 - 0.0057 16.7 3.0 0.53 10.4 0.1 3.4 3 0 0 3 3 3 2 NHR1 homology to TAF Flavin_Reduct PF01613.18 KLO15701.1 - 5e-22 78.6 0.1 7.4e-22 78.1 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Putative_PNPOx PF01243.20 KLO15701.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase ABC_tran PF00005.27 KLO15702.1 - 8.5e-22 78.1 0.0 1.8e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KLO15702.1 - 1e-10 42.0 0.1 4.9e-06 26.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KLO15702.1 - 5.9e-07 29.1 0.0 7.3e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KLO15702.1 - 0.0011 19.2 0.0 0.98 9.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KLO15702.1 - 0.0094 15.7 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KLO15702.1 - 0.011 16.2 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KLO15702.1 - 0.013 15.3 0.1 0.079 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KLO15702.1 - 0.018 15.0 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_13 PF13166.6 KLO15702.1 - 0.025 13.2 0.0 4.6 5.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KLO15702.1 - 0.025 14.9 0.0 0.074 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KLO15702.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 KLO15702.1 - 0.1 12.5 0.0 2.1 8.3 0.0 2.8 2 1 1 3 3 3 0 NACHT domain AAA_33 PF13671.6 KLO15702.1 - 0.12 12.6 0.0 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KLO15702.1 - 0.15 11.8 0.0 5.6 6.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein GTP_cyclohydroI PF01227.22 KLO15703.1 - 3.7e-74 248.0 0.1 4.6e-74 247.7 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KLO15703.1 - 0.00028 21.0 0.0 0.00068 19.7 0.0 1.6 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 KLO15703.1 - 0.054 13.5 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF3638 PF12340.8 KLO15703.1 - 0.097 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) THOC2_N PF16134.5 KLO15704.1 - 1.6e-147 492.8 0.0 7.1e-147 490.7 0.0 1.9 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KLO15704.1 - 8.7e-75 251.7 0.0 8.7e-75 251.7 0.0 2.0 3 0 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KLO15704.1 - 4.9e-29 100.2 0.0 1.1e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit DUF2458 PF10454.9 KLO15705.1 - 1.8e-09 37.5 0.9 3.5e-09 36.5 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DGCR6 PF07324.11 KLO15705.1 - 0.16 11.6 1.7 0.16 11.6 0.3 1.7 2 1 0 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein Ribosomal_L3 PF00297.22 KLO15706.1 - 8.7e-189 627.1 10.0 9.9e-189 626.9 10.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF2016 PF09436.10 KLO15710.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2016) PPR_2 PF13041.6 KLO15711.1 - 1.4e-10 41.2 0.0 0.0011 19.1 0.0 4.1 4 1 0 4 4 4 3 PPR repeat family PPR_1 PF12854.7 KLO15711.1 - 8.3e-09 35.0 0.1 4.6e-05 23.0 0.0 3.0 2 0 0 2 2 2 2 PPR repeat PPR PF01535.20 KLO15711.1 - 1.1e-07 31.7 0.1 0.00092 19.3 0.0 4.7 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.6 KLO15711.1 - 3.5e-07 30.2 0.0 0.001 19.1 0.0 3.3 2 1 0 2 2 2 2 Pentatricopeptide repeat domain AMMECR1 PF01871.17 KLO15712.1 - 4.7e-44 149.9 0.0 1.8e-43 148.1 0.0 1.9 1 1 1 2 2 2 1 AMMECR1 Ras PF00071.22 KLO15713.1 - 8e-47 158.8 0.0 7.3e-43 146.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KLO15713.1 - 4.6e-33 114.0 0.1 7e-33 113.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO15713.1 - 2.4e-11 43.4 0.1 4.5e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KLO15713.1 - 1.3e-07 31.7 0.0 2.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KLO15713.1 - 0.00068 19.1 0.0 0.00099 18.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KLO15713.1 - 0.0011 18.4 1.2 0.0049 16.3 0.0 2.3 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KLO15713.1 - 0.0016 18.7 0.1 0.0074 16.6 0.1 2.2 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 KLO15713.1 - 0.0019 18.0 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KLO15713.1 - 0.0037 17.7 0.0 0.009 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KLO15713.1 - 0.011 15.6 0.1 0.041 13.8 0.1 1.9 1 1 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KLO15713.1 - 0.018 14.6 0.3 0.033 13.7 0.3 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KLO15713.1 - 0.035 14.0 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KLO15713.1 - 0.053 13.3 0.2 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KLO15713.1 - 0.07 13.2 0.4 0.23 11.5 0.1 1.9 2 1 0 2 2 2 0 Dynamin family Septin PF00735.18 KLO15713.1 - 0.093 12.0 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Septin TniB PF05621.11 KLO15713.1 - 0.19 11.1 0.1 0.52 9.7 0.1 1.6 2 0 0 2 2 2 0 Bacterial TniB protein SSXT PF05030.12 KLO15714.1 - 0.00051 19.6 0.7 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 1 SSXT protein (N-terminal region) Ribosomal_L2_C PF03947.18 KLO15715.1 - 1.5e-45 154.4 2.3 1.5e-45 154.4 2.3 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KLO15715.1 - 1.3e-15 57.1 0.1 3.2e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Med26 PF08711.11 KLO15716.1 - 3e-08 33.5 0.1 6.4e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH_4 PF18044.1 KLO15716.1 - 5.8e-07 29.2 2.7 9.6e-07 28.5 2.7 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KLO15716.1 - 2e-06 27.5 3.0 3.7e-06 26.7 3.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KLO15716.1 - 1.3e-05 25.0 5.1 2.4e-05 24.2 5.1 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KLO15716.1 - 0.014 16.0 0.4 0.014 16.0 0.4 2.4 2 0 0 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 KLO15716.1 - 0.23 11.7 0.8 0.68 10.2 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger containing family HMG_box PF00505.19 KLO15717.1 - 5e-15 55.7 1.0 5e-15 55.7 1.0 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO15717.1 - 8.5e-13 48.7 0.7 8.5e-13 48.7 0.7 2.2 2 0 0 2 2 2 1 HMG-box domain SR-25 PF10500.9 KLO15717.1 - 4.2 6.9 27.3 3.5 7.2 3.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S9 PF00326.21 KLO15718.1 - 1.1e-05 25.0 0.0 5.8e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family PhoPQ_related PF10142.9 KLO15718.1 - 0.00076 18.2 0.0 0.0014 17.4 0.0 1.4 2 0 0 2 2 2 1 PhoPQ-activated pathogenicity-related protein DUF2048 PF09752.9 KLO15718.1 - 0.013 14.6 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 DLH PF01738.18 KLO15718.1 - 0.03 13.9 0.0 0.39 10.2 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 KLO15718.1 - 0.051 13.7 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Corona_3 PF04694.12 KLO15718.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Coronavirus ORF3 protein WW PF00397.26 KLO15719.1 - 7.6e-11 41.9 4.3 1.9e-10 40.7 4.3 1.7 1 0 0 1 1 1 1 WW domain NACHT PF05729.12 KLO15720.1 - 9.4e-09 35.4 0.0 2.2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 KLO15720.1 - 1.5e-08 35.1 5.8 1.3 10.0 0.1 6.2 6 1 1 7 7 5 3 WD domain, G-beta repeat AAA_16 PF13191.6 KLO15720.1 - 2.4e-06 28.0 0.0 5.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ANAPC4_WD40 PF12894.7 KLO15720.1 - 3.6e-06 27.2 0.0 7.6 6.9 0.0 4.7 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 KLO15720.1 - 0.00013 22.3 0.0 0.00034 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KLO15720.1 - 0.00022 20.5 0.1 0.00056 19.2 0.1 1.8 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KLO15720.1 - 0.0038 17.7 0.0 0.01 16.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PD40 PF07676.12 KLO15720.1 - 0.0043 16.9 0.0 2.7 8.0 0.0 3.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40_3 PF15911.5 KLO15720.1 - 0.0096 15.9 0.0 0.03 14.3 0.0 1.8 1 0 0 1 1 1 1 WD domain, G-beta repeat KAP_NTPase PF07693.14 KLO15720.1 - 0.011 15.0 0.8 0.02 14.2 0.6 1.5 1 1 0 1 1 1 0 KAP family P-loop domain eIF2A PF08662.11 KLO15720.1 - 0.013 15.4 0.0 0.069 13.0 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Parvo_NS1 PF01057.17 KLO15720.1 - 0.092 11.8 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KLO15720.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF1759 PF03564.15 KLO15721.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) NACHT PF05729.12 KLO15722.1 - 8.4e-09 35.6 0.0 1.6e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.11 KLO15722.1 - 1.8e-07 31.2 0.0 0.0047 16.8 0.0 2.6 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KLO15722.1 - 1.8e-06 28.6 10.2 0.048 14.5 0.7 7.0 8 0 0 8 8 7 2 WD domain, G-beta repeat AAA_22 PF13401.6 KLO15722.1 - 9.3e-06 26.0 0.0 2.8e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO15722.1 - 4.1e-05 24.0 0.1 0.00015 22.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ANAPC4_WD40 PF12894.7 KLO15722.1 - 6.6e-05 23.1 0.0 2.7 8.4 0.0 4.7 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 KLO15722.1 - 0.0015 18.5 0.0 0.0058 16.6 0.0 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat NB-ARC PF00931.22 KLO15722.1 - 0.0015 17.7 0.1 0.0054 15.9 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 KLO15722.1 - 0.021 15.2 0.0 0.053 14.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KLO15722.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea APS_kinase PF01583.20 KLO15722.1 - 0.081 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Ge1_WD40 PF16529.5 KLO15722.1 - 0.087 11.8 0.0 0.44 9.5 0.0 2.2 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KLO15722.1 - 0.089 12.4 0.0 0.77 9.3 0.0 2.1 2 0 0 2 2 2 0 PQQ-like domain Parvo_NS1 PF01057.17 KLO15722.1 - 0.16 11.0 0.1 0.33 10.0 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KLO15722.1 - 0.3 10.8 0.8 0.91 9.2 0.8 1.8 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.23 KLO15723.1 - 2.3e-49 168.0 0.0 7.2e-42 143.3 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO15723.1 - 3.4e-16 59.6 0.0 4.3e-14 52.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO15723.1 - 1e-05 25.6 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 KLO15723.1 - 1.9e-05 24.9 4.9 1.9e-05 24.9 4.9 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KLO15723.1 - 2.5e-05 24.1 6.0 2.5e-05 24.1 6.0 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KLO15723.1 - 0.00024 21.3 2.0 0.00063 20.0 2.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KLO15723.1 - 0.00026 20.8 4.4 0.00026 20.8 4.4 3.1 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KLO15723.1 - 0.00039 20.2 3.3 0.00097 18.9 3.3 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KLO15723.1 - 0.0029 17.6 0.3 0.0029 17.6 0.3 3.1 2 2 1 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KLO15723.1 - 0.0053 16.6 3.5 0.0053 16.6 3.5 2.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KLO15723.1 - 0.012 15.8 4.3 0.012 15.8 4.3 2.2 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING DEAD_2 PF06733.15 KLO15723.1 - 0.021 14.5 0.0 0.17 11.5 0.0 2.4 1 1 0 1 1 1 0 DEAD_2 zf-RING_6 PF14835.6 KLO15723.1 - 0.044 13.7 1.2 0.1 12.5 1.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KLO15723.1 - 0.067 13.2 0.4 0.067 13.2 0.4 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Maf_N PF08383.11 KLO15723.1 - 0.33 10.7 0.9 20 5.1 0.1 3.0 3 0 0 3 3 3 0 Maf N-terminal region WD40 PF00400.32 KLO15725.1 - 3.8e-07 30.7 9.0 0.075 13.9 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO15725.1 - 0.0083 16.4 0.0 17 5.8 0.0 4.0 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain SH3_1 PF00018.28 KLO15726.1 - 7.9e-06 25.4 0.4 0.00031 20.3 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KLO15726.1 - 3.3e-05 23.7 0.2 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KLO15726.1 - 0.0061 16.2 0.2 0.082 12.6 0.2 2.2 1 1 0 1 1 1 1 Variant SH3 domain Cyclin_N PF00134.23 KLO15727.1 - 1.3e-15 57.2 0.6 4e-15 55.7 0.2 1.8 1 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 KLO15727.1 - 8.1e-09 36.0 0.1 1e-08 35.7 0.1 1.2 1 1 0 1 1 1 1 Cyclin Zn_clus PF00172.18 KLO15728.1 - 5.6 7.2 9.2 5 7.3 0.8 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-FPG_IleRS PF06827.14 KLO15729.1 - 0.09 12.7 4.0 16 5.4 0.3 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS LIM_bind PF01803.16 KLO15730.1 - 1.8e-49 168.5 0.0 1e-45 156.2 0.0 2.0 2 0 0 2 2 2 2 LIM-domain binding protein S4 PF01479.25 KLO15732.1 - 5.1e-12 45.3 0.0 8.6e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KLO15732.1 - 1.1e-11 45.5 0.2 1.5e-11 45.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain AphA_like PF14557.6 KLO15732.1 - 0.016 15.0 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator DUF4139 PF13598.6 KLO15733.1 - 5.2e-38 130.9 0.0 2.9e-36 125.2 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KLO15733.1 - 4.2e-16 59.2 5.1 2.4e-14 53.6 5.1 2.9 1 1 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Baculo_PEP_C PF04513.12 KLO15733.1 - 0.0031 17.6 0.8 0.0065 16.5 0.8 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Jnk-SapK_ap_N PF09744.9 KLO15733.1 - 0.0098 16.1 2.1 0.024 14.8 2.1 1.6 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 CARDB PF07705.11 KLO15733.1 - 0.036 14.3 0.0 6.4 7.1 0.0 3.2 2 1 0 2 2 2 0 CARDB DUF4407 PF14362.6 KLO15733.1 - 0.045 13.1 1.1 0.09 12.1 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 KLO15733.1 - 0.048 13.7 4.2 0.12 12.4 4.2 1.6 1 0 0 1 1 1 0 FlxA-like protein DUF4139 PF13598.6 KLO15734.1 - 6.9e-43 146.8 2.0 7.6e-43 146.7 0.5 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KLO15734.1 - 6.8e-18 64.9 4.0 9.3e-18 64.5 0.1 3.0 2 1 1 3 3 3 1 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 KLO15734.1 - 0.00073 18.7 1.2 0.0015 17.7 1.2 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KLO15734.1 - 0.035 14.2 2.5 0.059 13.5 2.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 KLO15734.1 - 0.085 10.8 0.6 0.11 10.4 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CREPT PF16566.5 KLO15734.1 - 0.099 12.8 4.2 0.25 11.5 4.2 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Troponin PF00992.20 KLO15734.1 - 1.5 9.2 9.0 4 7.7 9.0 1.7 1 1 0 1 1 1 0 Troponin AAA_13 PF13166.6 KLO15734.1 - 1.7 7.2 8.9 2.7 6.6 8.9 1.2 1 0 0 1 1 1 0 AAA domain DUF16 PF01519.16 KLO15734.1 - 2.9 8.5 7.8 13 6.3 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 adh_short_C2 PF13561.6 KLO15735.1 - 7.8e-63 212.1 0.5 9.3e-63 211.9 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO15735.1 - 6.3e-44 149.8 0.6 7.8e-44 149.5 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO15735.1 - 6.2e-06 26.2 0.2 1.1e-05 25.5 0.2 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KLO15735.1 - 0.0053 16.7 0.5 0.011 15.6 0.5 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KLO15735.1 - 0.054 13.1 0.2 0.082 12.5 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RRM_1 PF00076.22 KLO15737.1 - 0.00065 19.5 0.0 0.082 12.7 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ARS2 PF04959.13 KLO15738.1 - 1.7e-17 64.5 2.1 2e-17 64.2 0.1 2.2 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 KLO15738.1 - 1.1e-15 57.8 0.3 3.1e-15 56.3 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 KLO15738.1 - 0.0019 17.9 1.8 0.0049 16.6 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.7 KLO15738.1 - 0.14 12.5 0.7 6 7.3 0.0 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) V_ATPase_I PF01496.19 KLO15738.1 - 0.25 9.2 0.4 0.43 8.4 0.4 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C2H2 PF00096.26 KLO15738.1 - 0.68 10.5 3.7 1.5 9.4 1.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Nuf2 PF03800.14 KLO15739.1 - 4.5e-35 120.8 0.0 4.5e-35 120.8 0.0 2.2 2 1 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 KLO15739.1 - 7.4e-20 71.2 19.8 7.4e-20 71.2 19.8 4.1 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain JIP_LZII PF16471.5 KLO15739.1 - 0.00084 19.5 3.9 0.00084 19.5 3.9 5.2 4 2 2 6 6 6 1 JNK-interacting protein leucine zipper II GAS PF13851.6 KLO15739.1 - 0.003 16.9 51.9 0.15 11.4 9.8 3.2 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KLO15739.1 - 0.01 15.9 19.7 0.01 15.9 19.7 4.6 2 2 3 5 5 5 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KLO15739.1 - 1.1 8.0 46.8 0.21 10.4 27.2 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_15 PF13175.6 KLO15739.1 - 3.6 7.2 23.4 5.6 6.6 23.4 1.4 1 0 0 1 1 1 0 AAA ATPase domain Sec34 PF04136.15 KLO15739.1 - 9.7 6.1 30.2 0.82 9.5 1.6 4.5 1 1 4 5 5 5 0 Sec34-like family AA_kinase PF00696.28 KLO15740.1 - 4.4e-42 144.3 1.5 6.9e-42 143.7 1.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KLO15740.1 - 3.1e-12 46.3 0.7 3.2e-05 23.8 0.1 2.8 3 0 0 3 3 3 2 PUA domain NCBP3 PF10309.9 KLO15742.1 - 1.5e-09 37.6 0.0 2.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 FoP_duplication PF13865.6 KLO15742.1 - 1.6e-05 25.4 14.4 1.6e-05 25.4 14.4 3.0 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 KH_8 PF17903.1 KLO15743.1 - 3.2e-32 110.5 0.1 5.5e-31 106.5 0.0 2.6 3 0 0 3 3 3 1 Krr1 KH1 domain KH_1 PF00013.29 KLO15743.1 - 0.00043 20.1 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KLO15743.1 - 0.066 13.1 0.8 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 KH domain PepSY_TM_like_2 PF16357.5 KLO15743.1 - 0.46 10.4 1.9 0.78 9.7 0.3 2.0 1 1 1 2 2 2 0 Putative PepSY_TM-like Methyltransf_11 PF08241.12 KLO15744.1 - 4e-16 59.4 0.0 7.1e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO15744.1 - 1.3e-11 45.0 0.0 3.2e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO15744.1 - 8.4e-09 36.1 0.0 1.7e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO15744.1 - 3.5e-07 30.2 0.0 6.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO15744.1 - 6e-05 22.9 0.0 8.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO15744.1 - 0.014 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Arrestin_N PF00339.29 KLO15745.1 - 1.8e-06 28.1 0.2 9.3e-05 22.5 0.0 3.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ACBP PF00887.19 KLO15746.1 - 9.7e-21 73.8 0.1 1.7e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein MRP-S34 PF16053.5 KLO15747.1 - 1.2e-11 44.3 0.4 2e-11 43.6 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 zf-MYND PF01753.18 KLO15748.1 - 0.0001 22.3 14.3 0.00018 21.5 14.3 1.4 1 0 0 1 1 1 1 MYND finger Vfa1 PF08432.10 KLO15749.1 - 2.2e-38 132.4 6.6 2.6e-38 132.2 6.6 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Atrophin-1 PF03154.15 KLO15749.1 - 9.7e-05 20.9 6.1 0.00012 20.6 6.1 1.1 1 0 0 1 1 1 1 Atrophin-1 family CPSF100_C PF13299.6 KLO15749.1 - 0.0081 16.4 5.2 0.0099 16.1 5.2 1.2 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal XRN_M PF17846.1 KLO15749.1 - 0.015 14.3 0.5 0.019 14.0 0.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain RR_TM4-6 PF06459.12 KLO15749.1 - 0.018 14.9 8.9 0.023 14.6 8.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 KLO15749.1 - 0.021 13.8 1.5 0.023 13.7 1.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pex14_N PF04695.13 KLO15749.1 - 0.025 15.3 6.5 0.033 14.8 6.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GNAT_acetyltr_2 PF13718.6 KLO15749.1 - 0.039 13.3 2.5 0.057 12.8 2.5 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Menin PF05053.13 KLO15749.1 - 0.04 12.3 3.7 0.043 12.2 3.7 1.0 1 0 0 1 1 1 0 Menin DUF5333 PF17267.2 KLO15749.1 - 0.04 14.1 0.8 0.07 13.3 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5333) RNA_pol_Rpc4 PF05132.14 KLO15749.1 - 0.041 14.3 7.2 0.059 13.8 7.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoIIP PF07454.11 KLO15749.1 - 0.068 12.6 7.4 0.079 12.4 7.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF3_subunit PF08597.10 KLO15749.1 - 0.082 12.8 23.3 0.13 12.2 23.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Borrelia_P83 PF05262.11 KLO15749.1 - 0.13 10.7 13.0 0.15 10.5 13.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein PPL5 PF18168.1 KLO15749.1 - 0.14 11.4 5.6 0.17 11.1 5.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 CDC45 PF02724.14 KLO15749.1 - 0.15 10.4 12.9 0.18 10.1 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 KLO15749.1 - 0.16 11.3 1.1 0.19 11.1 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NARP1 PF12569.8 KLO15749.1 - 0.16 10.9 13.6 0.21 10.5 13.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.12 KLO15749.1 - 0.19 11.1 11.9 0.25 10.7 11.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Zip PF02535.22 KLO15749.1 - 0.26 10.5 2.6 0.29 10.3 2.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 KLO15749.1 - 0.29 9.2 10.7 0.32 9.0 10.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Tim54 PF11711.8 KLO15749.1 - 0.41 9.4 12.0 0.51 9.1 12.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.15 KLO15749.1 - 0.42 9.3 7.3 0.49 9.1 7.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.11 KLO15749.1 - 0.42 9.1 11.4 0.56 8.7 11.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 KLO15749.1 - 0.46 9.2 6.7 0.53 9.0 6.7 1.1 1 0 0 1 1 1 0 Presenilin Eapp_C PF10238.9 KLO15749.1 - 0.53 10.4 6.8 0.76 9.8 6.8 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF2235 PF09994.9 KLO15749.1 - 0.58 9.5 2.9 0.82 9.0 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) FAM176 PF14851.6 KLO15749.1 - 0.62 9.7 9.1 0.9 9.2 9.1 1.3 1 0 0 1 1 1 0 FAM176 family CobT PF06213.12 KLO15749.1 - 0.73 9.2 13.5 1.2 8.5 13.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GCD14 PF08704.10 KLO15749.1 - 0.99 9.0 3.3 1.4 8.6 3.3 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit NPR3 PF03666.13 KLO15749.1 - 1.3 7.7 10.6 1.6 7.5 10.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_polI_A34 PF08208.11 KLO15749.1 - 2.3 8.3 24.1 3.4 7.7 24.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Hid1 PF12722.7 KLO15749.1 - 2.7 6.0 6.2 3 5.9 6.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2151 PF10221.9 KLO15749.1 - 3 6.3 9.2 3.5 6.1 9.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator MCM_bind PF09739.9 KLO15749.1 - 3.3 6.0 8.4 4.1 5.7 8.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RPN2_C PF18004.1 KLO15749.1 - 5 7.0 19.3 8 6.4 19.3 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4337 PF14235.6 KLO15749.1 - 6.3 6.9 5.8 8.3 6.5 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) U79_P34 PF03064.16 KLO15749.1 - 6.6 6.0 16.9 8.5 5.7 16.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Sec62 PF03839.16 KLO15749.1 - 7 6.1 10.4 8.3 5.9 10.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 KLO15749.1 - 7.5 6.2 10.6 10 5.8 10.6 1.2 1 0 0 1 1 1 0 Connexin ADH_N PF08240.12 KLO15750.1 - 6.9e-24 83.8 2.4 1.9e-23 82.4 2.4 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO15750.1 - 1.1e-18 67.5 0.1 2.3e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KLO15750.1 - 0.0072 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 KLO15750.1 - 0.016 14.5 1.2 0.052 12.9 0.8 1.9 2 0 0 2 2 2 0 ThiF family AlaDh_PNT_C PF01262.21 KLO15750.1 - 0.05 12.9 0.2 0.093 12.0 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F-box-like PF12937.7 KLO15751.1 - 2.3e-07 30.6 0.6 5.3e-07 29.4 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO15752.1 - 3e-09 36.6 1.1 1.3e-07 31.4 0.2 3.1 3 0 0 3 3 3 1 F-box-like Sec8_exocyst PF04048.14 KLO15752.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain F-box-like_2 PF13013.6 KLO15752.1 - 0.076 13.0 0.3 0.39 10.7 0.1 2.2 3 0 0 3 3 3 0 F-box-like domain F-box-like PF12937.7 KLO15753.1 - 2.4e-05 24.1 0.4 0.0013 18.6 0.1 2.7 2 0 0 2 2 2 2 F-box-like Hydrophobin PF01185.18 KLO15754.1 - 1.8e-17 63.7 3.7 2.2e-17 63.4 3.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin MTP18 PF10558.9 KLO15755.1 - 3.5e-63 212.6 4.0 4.7e-62 209.0 4.0 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) RNA_pol PF00940.19 KLO15755.1 - 0.016 14.0 0.0 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 DNA-dependent RNA polymerase IF-2B PF01008.17 KLO15756.1 - 4.5e-78 262.3 0.0 5.3e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family zf-H2C2_5 PF13909.6 KLO15756.1 - 0.086 12.6 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain IHABP4_N PF16174.5 KLO15756.1 - 5.5 7.6 9.8 8.3 7.0 9.8 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal XRN_N PF03159.18 KLO15757.1 - 3.9e-22 78.8 0.5 4.6e-22 78.6 0.5 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus NPP1 PF05630.11 KLO15757.1 - 0.039 14.1 0.3 0.049 13.8 0.3 1.1 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) DUF4646 PF15496.6 KLO15759.1 - 6.4e-07 30.0 0.0 1e-06 29.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Longin PF13774.6 KLO15760.1 - 1e-24 86.4 0.0 1.7e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KLO15760.1 - 2.7e-14 52.7 0.1 4.5e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 KLO15760.1 - 0.021 14.8 0.1 0.053 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein SLM4 GIT1_C PF12205.8 KLO15760.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF1664 PF07889.12 KLO15760.1 - 0.23 11.5 2.2 0.21 11.7 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF962 PF06127.11 KLO15761.1 - 5.8e-24 84.0 4.9 2e-23 82.2 4.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Glu-tRNAGln PF02686.15 KLO15762.1 - 0.012 15.8 0.1 0.029 14.7 0.1 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Hydrophobin PF01185.18 KLO15763.1 - 5e-15 55.9 6.9 6.2e-15 55.6 6.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Sporozoite_P67 PF05642.11 KLO15763.1 - 0.051 11.7 3.0 0.054 11.6 3.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hydrophobin PF01185.18 KLO15764.1 - 1.4e-15 57.7 5.0 1.7e-15 57.4 5.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin F-box-like PF12937.7 KLO15765.1 - 4e-07 29.8 7.9 5.8e-06 26.1 7.8 2.8 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO15765.1 - 0.0046 16.8 7.7 0.0046 16.8 7.7 3.3 4 1 0 4 4 4 1 F-box domain Peptidase_S10 PF00450.22 KLO15766.1 - 1.1e-98 331.4 0.0 1.4e-98 331.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase F-box-like PF12937.7 KLO15767.1 - 3.8e-07 29.9 6.3 6e-07 29.3 3.5 2.8 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO15767.1 - 0.048 13.5 6.2 0.53 10.2 3.8 3.4 2 1 0 2 2 2 0 F-box domain Methyltransf_13 PF08421.11 KLO15767.1 - 0.085 13.1 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Putative zinc binding domain DUF4974 PF16344.5 KLO15767.1 - 0.15 12.1 1.8 0.25 11.3 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4974) F-box-like PF12937.7 KLO15768.1 - 8.9e-08 31.9 1.9 6.6e-07 29.1 1.9 2.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO15768.1 - 0.21 11.5 4.5 1.1 9.2 1.9 3.2 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO15769.1 - 6.5e-09 35.5 9.3 1.8e-08 34.1 7.3 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO15769.1 - 0.0077 16.1 9.6 0.46 10.4 2.5 3.0 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.7 KLO15770.1 - 1.9e-05 24.5 3.0 1.9e-05 24.5 3.0 2.9 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 KLO15770.1 - 0.035 14.0 8.5 0.3 11.0 1.4 3.6 3 0 0 3 3 3 0 F-box domain Peptidase_S10 PF00450.22 KLO15771.1 - 3.4e-72 244.2 0.0 3e-71 241.1 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase F-box-like PF12937.7 KLO15772.1 - 5.6e-09 35.8 6.0 5.6e-09 35.8 6.0 3.0 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO15772.1 - 0.41 10.6 9.9 0.087 12.7 3.2 2.9 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO15774.1 - 5.3e-09 35.8 4.6 2.1e-08 33.9 4.6 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO15774.1 - 0.00023 21.0 3.0 0.0011 18.8 3.0 2.2 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO15775.1 - 9e-11 41.5 0.2 2.3e-10 40.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO15775.1 - 1.7 9.2 5.9 14 6.2 1.0 4.6 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Ferritin_2 PF13668.6 KLO15776.1 - 1.5e-33 115.9 0.6 2.3e-33 115.3 0.6 1.3 1 0 0 1 1 1 1 Ferritin-like domain EAF PF09816.9 KLO15777.1 - 9.1e-23 80.6 0.0 1.7e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor PGK PF00162.19 KLO15778.1 - 6.3e-144 479.6 0.0 7.1e-144 479.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase F-box-like PF12937.7 KLO15779.1 - 1.2e-10 41.1 0.4 2.5e-10 40.1 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO15780.1 - 5.4e-09 35.8 3.5 5.4e-09 35.8 3.5 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO15780.1 - 0.05 13.5 2.2 0.21 11.5 2.2 2.2 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO15781.1 - 0.00076 19.3 0.1 0.0063 16.4 0.1 2.6 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO15781.1 - 0.025 15.0 0.6 24 5.5 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Peptidase_S10 PF00450.22 KLO15782.1 - 2.1e-95 320.6 0.0 2.6e-95 320.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase F-box-like PF12937.7 KLO15783.1 - 2.8e-11 43.1 6.4 1.6e-10 40.7 6.4 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KLO15783.1 - 9.4e-05 22.2 3.9 0.0014 18.4 3.9 2.8 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO15784.1 - 1.2e-07 31.5 6.1 2.8e-07 30.3 2.2 2.7 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO15784.1 - 0.0007 19.4 1.5 0.011 15.6 0.7 3.0 2 1 0 2 2 2 1 F-box domain F-box-like_2 PF13013.6 KLO15784.1 - 0.13 12.3 0.3 0.32 11.0 0.3 1.6 1 0 0 1 1 1 0 F-box-like domain PUF PF00806.19 KLO15785.1 - 1.2e-15 56.2 0.0 0.0023 17.5 0.0 7.5 9 0 0 9 9 9 5 Pumilio-family RNA binding repeat Astacin PF01400.24 KLO15786.1 - 9.1e-08 31.9 0.6 3.5e-07 30.0 0.6 2.1 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KLO15786.1 - 8.3e-06 25.7 1.2 0.051 13.4 0.2 2.4 2 0 0 2 2 2 2 Matrixin Reprolysin_5 PF13688.6 KLO15786.1 - 0.0013 18.9 0.5 0.0024 18.1 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KLO15786.1 - 0.026 13.5 0.5 0.042 12.8 0.5 1.3 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 KLO15786.1 - 0.055 12.7 0.1 0.086 12.0 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.6 KLO15786.1 - 0.066 13.7 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF5127 PF17168.4 KLO15787.1 - 2.5e-52 177.9 0.5 7.1e-52 176.5 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO15787.1 - 1.1e-41 142.4 0.0 2.6e-41 141.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO15787.1 - 3e-30 105.9 0.0 6.1e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid6H PF17389.2 KLO15787.1 - 0.0018 17.6 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_52 PF03512.13 KLO15787.1 - 0.071 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 KAsynt_C_assoc PF16197.5 KLO15787.1 - 0.15 12.6 0.0 0.55 10.7 0.0 2.0 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension DUF5127 PF17168.4 KLO15788.1 - 1.5e-50 172.1 0.5 2.6e-50 171.3 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO15788.1 - 5.7e-36 123.8 0.0 3.2e-35 121.3 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO15788.1 - 3.4e-25 89.4 0.0 6.1e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Glyco_hydro_52 PF03512.13 KLO15788.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 52 Bac_rhamnosid6H PF17389.2 KLO15788.1 - 0.0019 17.5 0.0 0.005 16.2 0.0 1.6 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF5127 PF17168.4 KLO15790.1 - 6.5e-49 166.7 0.0 1.2e-48 165.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO15790.1 - 1.1e-43 148.8 0.1 2.5e-43 147.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO15790.1 - 1.4e-31 110.2 0.1 2.3e-31 109.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid6H PF17389.2 KLO15790.1 - 7.5e-05 22.1 0.0 7.5e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF4964 PF16334.5 KLO15790.1 - 0.17 11.5 0.1 0.4 10.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) DUF2273 PF10031.9 KLO15790.1 - 1.4 9.0 5.0 3.5 7.7 5.0 1.6 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) 2OG-FeII_Oxy_3 PF13640.6 KLO15791.1 - 2e-11 44.6 0.0 5.4e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.7 KLO15792.1 - 8.1e-06 25.6 3.5 1.9e-05 24.5 3.5 1.6 1 0 0 1 1 1 1 F-box-like DUF2431 PF10354.9 KLO15792.1 - 0.2 11.9 0.0 2 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2431) DUF5127 PF17168.4 KLO15793.1 - 6.7e-49 166.7 1.0 1.9e-48 165.2 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO15793.1 - 1.5e-41 141.9 0.1 4.2e-41 140.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO15793.1 - 2.3e-31 109.5 0.0 3.8e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid6H PF17389.2 KLO15793.1 - 0.00027 20.3 0.1 0.007 15.7 0.0 2.2 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Nitrate_red_gam PF02665.14 KLO15793.1 - 0.00057 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Nitrate reductase gamma subunit DUF4964 PF16334.5 KLO15793.1 - 0.00097 18.6 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydro_52 PF03512.13 KLO15793.1 - 0.0055 15.7 0.0 0.0082 15.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 52 DUF5127 PF17168.4 KLO15795.1 - 4e-53 180.5 0.4 3e-52 177.6 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO15795.1 - 2.2e-41 141.4 0.1 4.2e-41 140.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) Glyco_hydro_52 PF03512.13 KLO15795.1 - 0.00051 19.1 0.0 0.00072 18.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 52 Glyco_hydr_116N PF12215.8 KLO15795.1 - 0.02 14.4 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF5127 PF17168.4 KLO15796.1 - 6.3e-45 153.7 4.6 6.6e-45 153.7 0.5 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO15796.1 - 1.4e-40 138.8 0.3 3e-40 137.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO15796.1 - 8.1e-17 62.2 0.4 1.6e-16 61.2 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Glyco_hydro_52 PF03512.13 KLO15796.1 - 0.0011 18.0 0.0 0.002 17.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 52 Glyco_hydr_116N PF12215.8 KLO15796.1 - 0.023 14.2 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Bac_rhamnosid6H PF17389.2 KLO15796.1 - 0.063 12.5 0.0 0.13 11.5 0.0 1.5 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF4964 PF16334.5 KLO15796.1 - 0.15 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) DUF5127 PF17168.4 KLO15798.1 - 6.8e-51 173.2 0.0 1e-49 169.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO15798.1 - 7.9e-45 152.6 0.1 1.3e-44 151.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO15798.1 - 1.1e-16 61.7 0.0 2e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Glyco_hydro_52 PF03512.13 KLO15798.1 - 0.0021 17.1 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 52 Bac_rhamnosid6H PF17389.2 KLO15798.1 - 0.0084 15.4 0.4 0.019 14.2 0.0 1.7 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF5127 PF17168.4 KLO15800.1 - 9.4e-53 179.3 0.1 1.1e-51 175.8 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO15800.1 - 1.9e-37 128.6 0.0 3.8e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO15800.1 - 2e-26 93.4 0.0 4.9e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Glyco_hydro_52 PF03512.13 KLO15800.1 - 0.031 13.2 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 Glyco_hydr_116N PF12215.8 KLO15800.1 - 0.073 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF5127 PF17168.4 KLO15801.1 - 7.9e-54 182.8 1.2 1.2e-53 182.2 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO15801.1 - 7.4e-43 146.2 0.1 2.1e-42 144.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO15801.1 - 1.2e-29 103.9 0.0 2.5e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4270 PF14092.6 KLO15801.1 - 0.00027 20.2 0.1 0.00027 20.2 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4270) Glyco_hydro_52 PF03512.13 KLO15801.1 - 0.0077 15.2 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 52 Bac_rhamnosid6H PF17389.2 KLO15801.1 - 0.045 13.0 0.2 0.84 8.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF2461 PF09365.10 KLO15806.1 - 0.16 11.9 0.8 17 5.3 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) SNF2_N PF00176.23 KLO15808.1 - 2.5e-70 236.9 0.1 5.7e-70 235.8 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KLO15808.1 - 2.6e-39 133.8 1.2 2.6e-39 133.8 1.2 3.2 4 0 0 4 4 4 1 SLIDE HAND PF09110.11 KLO15808.1 - 4.1e-32 111.2 5.8 4.1e-32 111.2 5.8 2.6 2 0 0 2 2 1 1 HAND Helicase_C PF00271.31 KLO15808.1 - 9.3e-19 67.8 0.0 4.8e-18 65.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO15808.1 - 2.7e-11 43.8 0.0 1.1e-10 41.7 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KLO15808.1 - 1e-05 25.4 0.0 2.8e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KLO15808.1 - 0.00016 20.9 0.0 0.00041 19.6 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_14 PF13173.6 KLO15808.1 - 0.0061 16.6 0.2 0.026 14.5 0.0 2.3 2 0 0 2 2 1 1 AAA domain DBINO PF13892.6 KLO15808.1 - 0.012 15.9 0.2 0.012 15.9 0.2 3.4 4 0 0 4 4 3 0 DNA-binding domain ERCC3_RAD25_C PF16203.5 KLO15808.1 - 0.015 14.5 2.1 0.067 12.4 0.0 2.6 2 1 1 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase DEAD_2 PF06733.15 KLO15808.1 - 0.046 13.4 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_22 PF13401.6 KLO15808.1 - 0.11 12.7 2.2 5.7 7.2 0.0 3.7 3 0 0 3 3 3 0 AAA domain EI24 PF07264.11 KLO15809.1 - 2.4e-09 37.7 4.5 3.3e-09 37.3 4.5 1.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) AhpC-TSA_2 PF13911.6 KLO15810.1 - 1.4e-17 63.8 0.0 3.3e-17 62.6 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 KLO15810.1 - 1.5e-10 41.0 0.0 2.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KLO15810.1 - 7.7e-10 38.7 0.0 9.7e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 KLO15810.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin SMC_N PF02463.19 KLO15813.1 - 3.1e-75 252.4 1.2 6.4e-75 251.4 1.2 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KLO15813.1 - 1.2e-24 86.8 0.0 4e-24 85.2 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KLO15813.1 - 3.4e-11 43.5 9.4 7.2e-06 26.0 0.0 3.7 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KLO15813.1 - 3.6e-06 27.6 23.6 3.6e-06 27.6 23.6 7.1 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.6 KLO15813.1 - 1.6e-05 24.5 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KLO15813.1 - 0.00084 19.1 31.5 0.00084 19.1 31.5 4.1 2 2 1 3 3 3 1 AAA ATPase domain FlaC_arch PF05377.11 KLO15813.1 - 0.018 15.4 0.8 0.018 15.4 0.8 8.3 8 2 1 9 9 9 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 KLO15813.1 - 0.041 14.1 74.3 0.052 13.7 6.6 7.7 4 3 2 7 7 7 0 Fibrinogen alpha/beta chain family ABC_tran PF00005.27 KLO15813.1 - 0.34 11.4 0.0 0.34 11.4 0.0 5.7 4 2 0 4 4 4 0 ABC transporter DUF1932 PF09130.11 KLO15814.1 - 7.9e-16 57.8 0.0 1.8e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 KLO15814.1 - 3.3e-09 37.1 0.0 5.4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KLO15814.1 - 4e-07 30.5 0.0 8.6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KLO15814.1 - 0.00047 20.0 0.2 0.00098 19.0 0.2 1.5 1 0 0 1 1 1 1 Rossmann-like domain IlvN PF07991.12 KLO15814.1 - 0.00054 19.6 0.0 0.00096 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KLO15814.1 - 0.032 14.1 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase_Tyr PF07714.17 KLO15815.1 - 2.6e-41 141.6 0.0 3.9e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO15815.1 - 1.8e-35 122.6 0.0 3.2e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KLO15815.1 - 0.00045 19.1 0.0 0.00083 18.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO15815.1 - 0.0057 16.6 0.2 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_6 PF12697.7 KLO15816.1 - 1.1e-14 55.6 0.0 1.3e-14 55.3 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO15816.1 - 6.9e-11 42.3 0.2 2.2e-10 40.6 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO15816.1 - 5.1e-07 29.2 0.0 6.9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Mto2_bdg PF12808.7 KLO15818.1 - 0.086 13.1 2.3 0.15 12.4 2.3 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Erythro-docking PF09277.11 KLO15819.1 - 0.096 12.6 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 Erythronolide synthase, docking HA PF03457.14 KLO15820.1 - 0.11 12.9 0.3 0.51 10.7 0.1 2.2 2 1 0 2 2 2 0 Helicase associated domain DUF3128 PF11326.8 KLO15822.1 - 1.1e-17 64.1 2.1 5.8e-17 61.8 2.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) MFS_1 PF07690.16 KLO15824.1 - 6.1e-21 74.7 32.1 1.1e-16 60.7 17.1 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily Abhydrolase_6 PF12697.7 KLO15825.1 - 3e-17 64.0 0.1 4e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO15825.1 - 2.4e-12 47.0 0.0 2.6e-10 40.4 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO15825.1 - 3.7e-08 32.9 0.0 4.9e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 ADH_N PF08240.12 KLO15826.1 - 2.7e-23 81.9 0.1 5.7e-23 80.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO15826.1 - 8.8e-16 58.1 0.0 1.8e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KLO15826.1 - 3.6e-05 23.4 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 KLO15826.1 - 0.0028 17.9 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 KLO15826.1 - 0.0085 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KLO15826.1 - 0.013 14.8 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 KLO15826.1 - 0.023 14.1 0.1 0.037 13.4 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ADH_N_2 PF16884.5 KLO15826.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase FAD_binding_3 PF01494.19 KLO15826.1 - 0.12 11.6 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DUF4965 PF16335.5 KLO15829.1 - 7.2e-49 165.8 0.2 1.3e-48 165.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KLO15829.1 - 5.5e-46 157.2 0.1 2.5e-44 151.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KLO15829.1 - 1.2e-38 133.1 0.2 3.7e-38 131.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF3574 PF12098.8 KLO15830.1 - 0.096 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) DUF4818 PF16089.5 KLO15831.1 - 0.14 12.6 3.3 0.39 11.2 3.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4818) RIO1 PF01163.22 KLO15833.1 - 0.07 12.7 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Integrase_H2C2 PF17921.1 KLO15839.1 - 4.7e-05 23.4 0.1 7.2e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Spt5-NGN PF03439.13 KLO15840.1 - 1.9e-12 46.9 0.0 3.2e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KLO15840.1 - 2e-07 30.7 27.6 0.057 13.4 2.0 5.5 5 0 0 5 5 5 4 KOW motif HAS-barrel PF09378.10 KLO15840.1 - 0.036 14.2 2.6 2.1 8.6 0.0 3.4 3 0 0 3 3 3 0 HAS barrel domain Spt5_N PF11942.8 KLO15840.1 - 0.056 14.4 8.8 0.14 13.2 8.8 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF1326 PF07040.11 KLO15840.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) DUF4170 PF13773.6 KLO15852.1 - 0.029 14.5 0.0 0.096 12.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) p450 PF00067.22 KLO15853.1 - 4.7e-61 207.0 0.0 5.8e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KLO15854.1 - 1.5e-05 24.8 0.2 1.5e-05 24.8 0.2 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO15854.1 - 6.3 6.8 7.3 2 8.4 1.5 3.2 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO15855.1 - 1.3e-06 28.2 1.0 1.3e-06 28.2 1.0 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO15855.1 - 0.00069 19.4 0.2 0.0029 17.4 0.2 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO15856.1 - 1e-07 31.7 0.8 2.8e-07 30.3 0.8 1.8 1 0 0 1 1 1 1 F-box-like Cas9_a PF18470.1 KLO15857.1 - 0.023 14.2 0.2 2.4 7.6 0.1 2.4 2 0 0 2 2 2 0 Cas9 alpha-helical lobe domain FH2 PF02181.23 KLO15857.1 - 0.21 10.7 1.8 0.57 9.2 0.1 2.0 2 0 0 2 2 2 0 Formin Homology 2 Domain DUF2370 PF10176.9 KLO15858.1 - 2.2e-74 249.9 0.0 3.9e-74 249.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Ank_2 PF12796.7 KLO15859.1 - 1.2e-19 70.7 0.1 5.5e-13 49.3 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KLO15859.1 - 2.5e-17 63.0 2.6 1.3e-10 41.6 0.2 4.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KLO15859.1 - 2.9e-14 52.9 0.5 4.3e-07 30.1 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KLO15859.1 - 3.8e-11 42.2 1.9 0.00018 21.7 0.1 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KLO15859.1 - 1.2e-10 41.3 2.3 3.1e-06 27.4 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat CUB_2 PF02408.20 KLO15859.1 - 0.3 10.9 2.6 2.1 8.2 0.1 2.4 2 0 0 2 2 2 0 CUB-like domain tRNA_synthFbeta PF17759.1 KLO15860.1 - 7.1e-51 172.7 0.0 1e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KLO15860.1 - 3.8e-31 107.1 0.0 7.6e-29 99.8 0.0 2.5 2 0 0 2 2 2 2 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KLO15860.1 - 1.1e-27 96.8 0.1 2e-27 96.0 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KLO15860.1 - 1.4e-19 70.1 0.0 1.1e-16 60.9 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetase B5 domain DUF469 PF04320.14 KLO15860.1 - 0.0087 16.9 0.1 0.027 15.3 0.1 1.9 1 0 0 1 1 1 1 Protein with unknown function (DUF469) MFS_1 PF07690.16 KLO15861.1 - 3.9e-08 32.6 29.2 9.4e-06 24.8 21.8 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KLO15861.1 - 7.8e-07 28.0 3.2 7.8e-07 28.0 3.2 4.1 4 1 0 4 4 4 2 MFS/sugar transport protein ATG22 PF11700.8 KLO15861.1 - 0.0072 15.0 0.5 0.04 12.5 0.1 2.3 3 0 0 3 3 3 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 KLO15861.1 - 0.26 10.1 6.1 0.02 13.7 0.3 2.1 2 1 0 2 2 2 0 MFS_1 like family Diphthami_syn_2 PF01902.17 KLO15862.1 - 2.9e-40 138.1 0.0 5.1e-32 111.2 0.0 2.1 2 0 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KLO15862.1 - 1.7e-21 76.5 0.0 6.1e-11 42.4 0.0 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.16 KLO15862.1 - 0.086 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Cactin_mid PF10312.9 KLO15863.1 - 1.6e-62 210.8 4.9 1.6e-62 210.8 4.9 3.2 4 1 0 4 4 4 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KLO15863.1 - 1.6e-59 199.3 7.7 3.1e-59 198.4 7.7 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein RCSD PF05177.12 KLO15863.1 - 0.022 15.7 1.3 0.022 15.7 1.3 3.1 3 0 0 3 3 3 0 RCSD region JAB PF01398.21 KLO15864.1 - 3.7e-32 110.8 0.1 6.4e-32 110.0 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KLO15864.1 - 5e-13 49.5 1.3 9.3e-13 48.6 1.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KLO15864.1 - 1.2e-06 28.2 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 KLO15864.1 - 0.011 15.8 0.3 0.024 14.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) UPF0172 PF03665.13 KLO15864.1 - 0.19 11.8 1.8 0.66 10.0 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) YIF1 PF03878.15 KLO15865.1 - 1.6e-87 293.0 0.2 2e-87 292.7 0.2 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KLO15865.1 - 0.00075 19.3 3.1 0.0018 18.0 3.1 1.6 1 0 0 1 1 1 1 Yip1 domain Phage_holin_2_1 PF04971.12 KLO15865.1 - 0.098 12.7 0.6 0.28 11.2 0.6 1.8 1 0 0 1 1 1 0 Bacteriophage P21 holin S Syntaxin-18_N PF10496.9 KLO15866.1 - 1.7e-18 66.6 1.3 1.7e-18 66.6 1.3 3.0 3 1 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KLO15866.1 - 0.00015 21.7 2.7 0.01 15.8 0.0 3.1 3 0 0 3 3 3 2 SNARE domain SUa-2TM PF18179.1 KLO15866.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain TipAS PF07739.13 KLO15866.1 - 2.5 8.7 8.8 0.31 11.6 2.0 2.7 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain DUF16 PF01519.16 KLO15866.1 - 6.9 7.2 9.5 2.7 8.5 3.2 2.9 3 0 0 3 3 3 0 Protein of unknown function DUF16 SNARE_assoc PF09335.11 KLO15867.1 - 5e-13 49.6 12.9 3.4e-12 46.9 9.2 2.6 3 0 0 3 3 3 1 SNARE associated Golgi protein Afaf PF15339.6 KLO15867.1 - 0.24 11.1 0.2 2.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Acrosome formation-associated factor DUF3402 PF11882.8 KLO15868.1 - 2.1e-110 370.0 2.1 6.6e-109 365.1 2.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KLO15868.1 - 2.1e-69 233.9 0.3 3.3e-69 233.3 0.3 1.2 1 0 0 1 1 1 1 N1221-like protein Cyclin PF08613.11 KLO15869.1 - 0.019 15.3 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 Cyclin ThiF PF00899.21 KLO15870.1 - 7.9e-110 366.0 0.0 1.7e-71 240.4 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KLO15870.1 - 1.7e-86 290.2 0.1 2.8e-86 289.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KLO15870.1 - 1.2e-35 121.5 0.1 2.7e-35 120.4 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KLO15870.1 - 4.9e-28 97.7 0.7 9.4e-28 96.8 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KLO15870.1 - 2.8e-25 88.3 0.7 6.8e-25 87.0 0.7 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 KLO15870.1 - 0.021 14.9 0.1 0.089 12.9 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KLO15870.1 - 0.19 12.3 0.6 42 4.8 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SlyX PF04102.12 KLO15872.1 - 1.9 9.2 28.2 0.63 10.7 1.5 4.3 3 1 2 5 5 5 0 SlyX P4Ha_N PF08336.11 KLO15872.1 - 2.7 8.0 9.2 2 8.4 2.9 2.8 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Mt_ATP-synt_D PF05873.12 KLO15872.1 - 3.3 7.6 7.6 0.15 11.9 1.2 2.0 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Sec20 PF03908.13 KLO15872.1 - 6.4 6.8 9.9 0.97 9.4 1.7 2.9 1 1 1 2 2 2 0 Sec20 DNA_pol_D_N PF18018.1 KLO15873.1 - 1.1e-37 129.1 0.0 2e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KLO15873.1 - 4.2e-31 108.0 0.1 8.3e-31 107.0 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Fungal_trans PF04082.18 KLO15874.1 - 2.8e-18 65.9 0.5 4.6e-18 65.2 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO15874.1 - 3.9e-07 30.1 8.2 9.1e-07 28.9 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Diphthamide_syn PF01866.17 KLO15875.1 - 1.6e-96 323.4 0.0 8.2e-59 199.5 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein RRM_1 PF00076.22 KLO15876.1 - 1.9e-11 43.6 0.0 2.9e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KLO15876.1 - 4.6e-06 26.2 0.0 7.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPC1_N PF16414.5 KLO15877.1 - 1.3e-77 260.7 7.9 1.8e-77 260.2 7.9 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KLO15877.1 - 1.2e-70 238.7 1.5 3.2e-36 124.8 0.1 3.0 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 KLO15877.1 - 3.8e-45 153.5 17.8 2.6e-24 85.8 0.4 3.7 3 1 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 KLO15877.1 - 3.9e-05 21.5 3.3 6.6e-05 20.8 3.3 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Folate_rec PF03024.14 KLO15877.1 - 7e-05 22.8 1.9 0.00015 21.7 1.9 1.5 1 0 0 1 1 1 1 Folate receptor family zf-H2C2_2 PF13465.6 KLO15879.1 - 9.7e-09 35.3 10.4 1.2e-05 25.5 0.2 3.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KLO15879.1 - 1.4e-07 31.6 11.3 0.00011 22.5 3.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO15879.1 - 1.3e-05 25.6 7.4 0.014 16.2 0.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KLO15879.1 - 0.005 17.2 2.9 2.2 8.8 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KLO15879.1 - 0.0079 16.5 4.1 0.2 12.0 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding HMMR_N PF15905.5 KLO15879.1 - 0.25 10.8 0.0 0.25 10.8 0.0 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal NAD_binding_1 PF00175.21 KLO15880.1 - 1.9e-16 60.6 0.0 3.1e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KLO15880.1 - 1.4e-07 31.8 0.0 2.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KLO15880.1 - 3.5e-06 27.2 0.0 0.00029 21.0 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain tRNA-synt_2d PF01409.20 KLO15881.1 - 1.3e-87 293.3 0.0 1.8e-87 292.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KLO15881.1 - 2.7e-17 62.8 0.5 1.4e-16 60.5 0.1 2.4 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KLO15881.1 - 4.6e-11 42.6 0.0 3.7e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 KLO15881.1 - 0.00088 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 KLO15881.1 - 0.0026 16.9 0.0 0.012 14.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 KLO15881.1 - 0.056 13.4 0.5 0.12 12.4 0.5 1.6 1 0 0 1 1 1 0 PheRS DNA binding domain 2 HTH_45 PF14947.6 KLO15881.1 - 0.12 12.4 0.0 4.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix ParA PF10609.9 KLO15882.1 - 3.8e-77 259.1 0.1 4.6e-77 258.8 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KLO15882.1 - 1.3e-08 34.9 0.0 3.4e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KLO15882.1 - 8.3e-05 22.6 0.5 0.019 14.9 0.2 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 KLO15882.1 - 0.007 15.7 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 KLO15882.1 - 0.013 15.1 0.1 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 KLO15882.1 - 0.016 14.5 3.2 0.15 11.2 1.6 2.4 3 0 0 3 3 3 0 Anion-transporting ATPase AAA_26 PF13500.6 KLO15882.1 - 0.092 12.6 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KLO15882.1 - 0.12 11.5 0.2 0.21 10.7 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain Metalloenzyme PF01676.18 KLO15883.1 - 0.055 12.8 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Imm42 PF15593.6 KLO15883.1 - 0.3 11.6 5.0 10 6.6 0.1 2.9 2 1 1 3 3 3 0 Immunity protein 42 AAA_2 PF07724.14 KLO15884.1 - 1.6e-36 126.0 0.0 2.8e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KLO15884.1 - 1.9e-15 57.5 0.0 3.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KLO15884.1 - 9.5e-09 35.2 0.0 2.4e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.21 KLO15884.1 - 2.1e-05 24.0 0.1 0.00053 19.4 0.0 2.7 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KLO15884.1 - 0.00011 22.5 0.1 0.0038 17.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KLO15884.1 - 0.00013 22.0 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KLO15884.1 - 0.0021 18.2 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KLO15884.1 - 0.0041 16.9 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KLO15884.1 - 0.0048 16.7 0.0 0.088 12.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KLO15884.1 - 0.0062 17.0 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter DEAD PF00270.29 KLO15884.1 - 0.0089 15.8 0.0 0.037 13.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_7 PF12775.7 KLO15884.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KLO15884.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 KLO15884.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 KLO15884.1 - 0.04 13.4 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 KLO15884.1 - 0.041 14.3 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_3 PF07726.11 KLO15884.1 - 0.042 13.7 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KLO15884.1 - 0.042 13.8 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KLO15884.1 - 0.046 13.4 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KLO15884.1 - 0.071 13.5 0.0 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase MCM PF00493.23 KLO15884.1 - 0.08 12.0 0.1 0.66 9.0 0.1 2.3 2 1 0 2 2 2 0 MCM P-loop domain Sigma54_activ_2 PF14532.6 KLO15884.1 - 0.088 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 KLO15884.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 KLO15884.1 - 0.19 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ran_BP1 PF00638.18 KLO15885.1 - 2.8e-51 172.9 1.2 4.4e-51 172.3 1.2 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KLO15885.1 - 0.00018 21.4 0.2 0.00051 20.0 0.2 1.7 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KLO15885.1 - 0.051 13.8 0.0 0.077 13.3 0.0 1.2 1 0 0 1 1 1 0 VID27 PH-like domain EMP24_GP25L PF01105.24 KLO15886.1 - 1.3e-52 178.4 0.4 1.5e-52 178.2 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kinesin PF00225.23 KLO15887.1 - 1.7e-106 355.9 0.0 2.8e-106 355.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KLO15887.1 - 5.5e-22 78.3 0.0 9.9e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding TPR_MLP1_2 PF07926.12 KLO15887.1 - 1.1 9.4 15.9 0.85 9.7 4.3 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 KLO15887.1 - 1.4 8.6 10.9 2.8 7.6 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Apolipoprotein PF01442.18 KLO15887.1 - 2.1 8.2 21.7 8.7 6.2 21.7 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain YabA PF06156.13 KLO15887.1 - 6.6 7.4 6.9 9.1 7.0 2.3 2.7 2 0 0 2 2 2 0 Initiation control protein YabA Cnn_1N PF07989.11 KLO15887.1 - 9.2 6.5 11.4 1.2 9.4 3.4 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Nucleos_tra2_C PF07662.13 KLO15888.1 - 1.7e-71 240.4 5.3 1.7e-71 240.4 5.3 1.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KLO15888.1 - 4.1e-21 75.3 4.8 4.1e-21 75.3 4.8 4.2 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KLO15888.1 - 0.00048 20.4 19.8 0.018 15.3 6.8 3.2 2 1 0 2 2 2 2 Nucleoside recognition Amidohydro_2 PF04909.14 KLO15889.1 - 2e-06 27.8 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 KLO15889.1 - 2.8e-06 26.9 0.0 7.7e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Plasmid_RAQPRD PF09686.10 KLO15891.1 - 0.13 12.5 0.3 0.13 12.5 0.3 2.2 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) MIF4G_like_2 PF09090.11 KLO15891.1 - 0.46 9.9 5.0 0.26 10.7 3.3 1.4 1 1 0 1 1 1 0 MIF4G like DUF4472 PF14739.6 KLO15891.1 - 4.2 8.2 9.2 0.18 12.5 2.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) DUF1764 PF08576.10 KLO15893.1 - 3.1e-22 79.3 19.6 1.1e-20 74.4 5.1 2.2 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) DUF641 PF04859.12 KLO15893.1 - 0.059 13.7 2.8 0.1 12.9 2.8 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Peptidase_S64 PF08192.11 KLO15893.1 - 0.33 9.4 8.3 0.37 9.2 8.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 CCSAP PF15748.5 KLO15893.1 - 1.9 8.6 14.6 2.4 8.3 14.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated GAS2 PF02187.17 KLO15894.1 - 3.3e-12 46.3 0.0 1.2e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain DHO_dh PF01180.21 KLO15895.1 - 4.5e-92 308.4 0.0 5.4e-92 308.1 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KLO15895.1 - 0.0016 17.5 0.7 0.38 9.7 2.1 2.8 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KLO15895.1 - 0.021 14.3 0.1 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ADH_N PF08240.12 KLO15896.1 - 3.8e-30 104.0 0.7 6.2e-30 103.3 0.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO15896.1 - 2e-23 82.8 0.0 3e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KLO15896.1 - 1.4e-06 27.9 0.3 0.025 14.1 0.1 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KLO15896.1 - 0.00013 23.0 0.3 0.00087 20.4 0.3 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KLO15896.1 - 0.0063 17.2 0.1 0.014 16.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 KLO15896.1 - 0.025 13.9 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PrmA PF06325.13 KLO15896.1 - 0.037 13.4 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UDPG_MGDP_dh_N PF03721.14 KLO15896.1 - 0.047 13.3 0.1 0.093 12.3 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KLO15896.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTS PF05175.14 KLO15896.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain EzrA PF06160.12 KLO15898.1 - 0.00072 17.9 0.5 0.00092 17.5 0.5 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA PIEZO PF15917.5 KLO15898.1 - 0.076 12.5 0.1 0.089 12.3 0.1 1.1 1 0 0 1 1 1 0 Piezo PKcGMP_CC PF16808.5 KLO15898.1 - 0.076 12.9 6.0 0.13 12.1 4.8 2.1 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF812 PF05667.11 KLO15898.1 - 0.62 8.9 5.8 0.042 12.7 0.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF812) zf-RING_5 PF14634.6 KLO15899.1 - 2.2e-08 33.9 9.6 4e-08 33.1 9.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KLO15899.1 - 2.5e-05 24.5 9.5 2.6e-05 24.5 6.1 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KLO15899.1 - 4.5e-05 23.2 9.3 0.00024 20.9 9.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO15899.1 - 8e-05 22.4 9.6 0.0001 22.1 6.1 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KLO15899.1 - 9.7e-05 22.1 9.9 0.00021 21.1 6.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO15899.1 - 0.00032 20.5 10.6 0.0065 16.3 10.8 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KLO15899.1 - 0.0011 18.8 2.8 0.0011 18.8 2.8 1.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KLO15899.1 - 0.0061 16.8 5.5 0.012 15.9 5.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KLO15899.1 - 0.007 16.1 2.9 0.007 16.1 2.9 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zinc-ribbon_6 PF10005.9 KLO15899.1 - 0.0071 17.0 0.8 0.027 15.2 0.6 2.0 1 1 1 2 2 2 1 zinc-ribbon domain zinc_ribbon_11 PF11682.8 KLO15899.1 - 0.011 15.7 0.9 0.029 14.4 0.8 1.6 2 0 0 2 2 2 0 Probable zinc-ribbon DZR PF12773.7 KLO15899.1 - 0.025 14.6 1.5 0.025 14.6 1.5 1.9 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KLO15899.1 - 0.026 14.0 0.4 0.069 12.6 0.4 1.8 1 0 0 1 1 1 0 zinc-ribbon domain DUF1272 PF06906.11 KLO15899.1 - 0.036 14.1 6.2 0.066 13.3 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-P11 PF03854.14 KLO15899.1 - 0.071 12.8 6.4 0.14 11.9 6.4 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 KLO15899.1 - 0.13 12.4 12.1 0.17 12.1 4.9 3.4 2 1 2 4 4 4 0 zinc finger of C3HC4-type, RING Siva PF05458.12 KLO15899.1 - 0.34 10.6 5.4 0.51 10.0 5.4 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_UBOX PF13445.6 KLO15899.1 - 0.81 9.8 13.2 1.9 8.6 7.8 3.2 2 1 1 3 3 3 0 RING-type zinc-finger zf-C3HC4_5 PF17121.5 KLO15899.1 - 2.3 8.2 7.6 0.43 10.5 3.3 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Spindle_Spc25 PF08234.12 KLO15900.1 - 1.4e-19 70.1 0.7 6.4e-19 67.9 0.0 2.4 3 0 0 3 3 3 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 KLO15900.1 - 0.00011 21.3 11.9 0.00014 20.9 11.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein BST2 PF16716.5 KLO15900.1 - 0.00028 21.4 8.6 0.00028 21.4 8.6 2.1 2 0 0 2 2 2 1 Bone marrow stromal antigen 2 Golgin_A5 PF09787.9 KLO15900.1 - 0.006 16.1 13.9 0.0082 15.6 13.9 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Filament PF00038.21 KLO15900.1 - 0.02 14.5 14.7 0.028 14.0 14.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein TRIQK PF15168.6 KLO15900.1 - 0.54 10.2 6.6 2 8.4 0.1 3.2 1 1 2 3 3 3 0 Triple QxxK/R motif-containing protein family CENP-K PF11802.8 KLO15900.1 - 0.8 9.2 13.2 1 8.9 13.2 1.2 1 0 0 1 1 1 0 Centromere-associated protein K FapA PF03961.13 KLO15900.1 - 1.3 7.6 10.3 1.6 7.3 10.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4366 PF14283.6 KLO15900.1 - 1.4 9.0 9.1 1.1 9.4 5.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) BRE1 PF08647.11 KLO15900.1 - 3 8.0 19.2 0.053 13.6 7.6 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Pkinase PF00069.25 KLO15901.1 - 4.2e-43 147.6 0.0 5.3e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO15901.1 - 2.7e-23 82.6 0.0 3.6e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO15901.1 - 0.00061 19.2 0.0 0.0023 17.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KLO15901.1 - 0.0023 17.9 0.1 0.019 14.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KLO15901.1 - 0.0053 16.1 0.0 0.0098 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KLO15901.1 - 0.0067 15.4 0.0 0.013 14.5 0.0 1.4 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 KLO15901.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 WD40 PF00400.32 KLO15902.1 - 5.5e-09 36.5 4.9 0.32 11.9 0.0 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat Lactonase PF10282.9 KLO15902.1 - 1.4e-05 24.5 0.0 0.092 12.0 0.0 2.3 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller GEN1_C PF18380.1 KLO15902.1 - 0.03 15.2 0.0 0.057 14.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Wtap PF17098.5 KLO15903.1 - 7.4e-14 52.0 10.9 3.4e-12 46.6 10.9 2.3 1 1 0 1 1 1 1 WTAP/Mum2p family DUF2594 PF10769.9 KLO15903.1 - 0.0024 17.8 0.2 0.0071 16.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2594) WD40_alt PF14077.6 KLO15903.1 - 0.12 12.3 3.0 2.8 7.9 0.2 2.7 2 0 0 2 2 2 0 Alternative WD40 repeat motif TMF_DNA_bd PF12329.8 KLO15903.1 - 5.1 7.2 19.1 1.4 9.0 0.2 3.5 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Glyco_hydro_18 PF00704.28 KLO15905.1 - 1e-56 192.9 1.0 1.5e-56 192.4 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PapD_C PF02753.17 KLO15905.1 - 0.16 12.4 1.7 0.36 11.2 0.1 2.5 2 1 0 2 2 2 0 Pili assembly chaperone PapD, C-terminal domain SPX PF03105.19 KLO15905.1 - 5.1 6.9 6.0 1.6 8.6 3.3 1.5 2 0 0 2 2 2 0 SPX domain FH2 PF02181.23 KLO15906.1 - 2.3e-86 290.3 0.0 2.3e-86 290.3 0.0 2.3 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KLO15906.1 - 1.7e-25 89.7 0.3 1.7e-25 89.7 0.3 2.8 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KLO15906.1 - 1.9e-16 60.3 1.7 4.6e-16 59.0 0.1 2.4 2 1 1 3 3 3 1 Diaphanous FH3 Domain Fez1 PF06818.15 KLO15906.1 - 0.31 11.5 19.9 2.2 8.7 4.7 2.8 1 1 1 2 2 2 0 Fez1 TMCO5 PF14992.6 KLO15906.1 - 1.2 8.7 12.6 2.5 7.6 12.6 1.5 1 0 0 1 1 1 0 TMCO5 family DUF4407 PF14362.6 KLO15906.1 - 2 7.7 10.8 0.36 10.1 6.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Muted PF14942.6 KLO15906.1 - 4 7.8 12.5 0.77 10.1 7.6 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Acetyltransf_10 PF13673.7 KLO15907.1 - 4.4e-08 33.1 0.0 0.0034 17.3 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 KLO15907.1 - 3.1e-05 24.6 0.1 0.0016 19.1 0.1 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO15907.1 - 4.6e-05 23.8 0.0 8.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO15907.1 - 0.00024 21.3 0.0 0.00091 19.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family HMG_box PF00505.19 KLO15908.1 - 1.1e-13 51.4 12.4 8e-09 35.8 3.5 2.9 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO15908.1 - 1.1e-12 48.3 8.4 4.3e-06 27.2 0.7 2.5 2 0 0 2 2 2 2 HMG-box domain GRIM-19 PF06212.12 KLO15909.1 - 3.7e-30 104.6 0.0 4.2e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein DUF3545 PF12065.8 KLO15910.1 - 0.021 14.8 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) Prefoldin_2 PF01920.20 KLO15911.1 - 6.9e-21 74.2 1.2 8.5e-21 73.9 1.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KLO15911.1 - 0.021 14.7 0.8 0.052 13.5 0.8 1.5 1 1 0 1 1 1 0 Prefoldin subunit DUF4924 PF16271.5 KLO15911.1 - 0.043 13.8 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) Cep57_MT_bd PF06657.13 KLO15911.1 - 0.081 13.4 2.2 2.4 8.7 1.3 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 HTH_Tnp_Tc5 PF03221.16 KLO15911.1 - 0.094 12.8 0.6 0.15 12.1 0.1 1.6 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain APG6_N PF17675.1 KLO15911.1 - 0.48 10.9 6.7 2.6 8.6 6.2 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region Fer4 PF00037.27 KLO15912.1 - 1.9e-14 52.7 16.4 1.7e-08 33.9 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KLO15912.1 - 3.1e-13 50.1 10.3 4.9e-13 49.4 10.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KLO15912.1 - 7.9e-10 39.5 10.7 2.6e-05 25.1 1.0 2.2 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KLO15912.1 - 9.7e-10 38.4 6.1 0.00012 22.2 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KLO15912.1 - 1.4e-09 37.9 21.3 1.1e-06 28.6 12.3 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KLO15912.1 - 1.4e-08 34.8 10.5 2.2e-08 34.1 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KLO15912.1 - 1.7e-08 34.7 4.2 0.00018 21.9 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KLO15912.1 - 3.8e-07 29.9 17.8 0.00039 20.4 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KLO15912.1 - 9.9e-07 28.5 12.1 0.0023 17.9 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KLO15912.1 - 6.1e-06 26.3 11.0 0.00031 21.0 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KLO15912.1 - 0.00013 22.4 11.2 0.03 14.9 12.3 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 KLO15912.1 - 0.00049 20.6 10.4 0.081 13.5 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 KLO15912.1 - 0.021 15.0 5.5 0.87 9.9 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KLO15912.1 - 0.054 13.7 9.3 1.1 9.5 1.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KLO15912.1 - 0.2 12.7 16.3 0.34 12.0 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KLO15912.1 - 0.27 12.1 11.6 1.4 9.8 1.3 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KLO15912.1 - 0.32 11.1 6.6 2 8.6 1.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S EPF PF17181.4 KLO15912.1 - 0.65 10.1 6.2 0.53 10.3 0.6 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins ArfGap PF01412.18 KLO15913.1 - 7.6e-34 116.3 0.1 1.6e-33 115.2 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DNA_mis_repair PF01119.19 KLO15914.1 - 4.6e-14 52.1 0.0 8.1e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KLO15914.1 - 1.1e-08 34.9 0.0 2.7e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KLO15914.1 - 3.3e-05 23.7 0.0 0.00042 20.1 0.0 2.5 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KLO15914.1 - 0.00016 22.1 0.0 0.00052 20.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2835 PF11197.8 KLO15914.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) SBDS PF01172.18 KLO15915.1 - 2.6e-09 37.0 0.1 3.2e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein IU_nuc_hydro PF01156.19 KLO15916.1 - 5.5e-87 292.2 0.0 6.4e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF202 PF02656.15 KLO15917.1 - 6.3e-15 55.4 4.0 8.3e-15 55.0 1.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SANT_DAMP1_like PF16282.5 KLO15919.1 - 1.7e-31 108.2 2.8 2.9e-31 107.5 2.8 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 KLO15919.1 - 6.3e-05 23.1 0.0 0.0003 20.9 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KLO15919.1 - 0.00028 21.1 0.0 0.0011 19.2 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain APG6_N PF17675.1 KLO15919.1 - 0.0034 17.9 1.3 0.0034 17.9 1.3 2.5 2 0 0 2 2 2 1 Apg6 coiled-coil region TipE PF16972.5 KLO15919.1 - 1.5 7.9 6.4 2.2 7.4 6.4 1.2 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE RhoGEF PF00621.20 KLO15923.1 - 0.00029 21.1 0.0 0.00049 20.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain RhoGEF PF00621.20 KLO15924.1 - 1.1e-11 45.4 0.0 2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain p450 PF00067.22 KLO15926.1 - 2.7e-65 220.9 0.0 3.5e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CHCH PF06747.13 KLO15928.1 - 7.6e-05 22.7 7.9 0.0097 16.0 0.0 3.3 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KLO15928.1 - 0.15 12.1 6.9 4.9 7.2 0.1 3.2 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KLO15928.1 - 0.84 10.0 9.4 1.7 9.0 5.8 2.6 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.16 KLO15928.1 - 9.4 6.5 11.6 3.5 7.9 5.4 2.7 2 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein BPL_LplA_LipB PF03099.19 KLO15929.1 - 0.0077 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family F-box-like PF12937.7 KLO15930.1 - 0.026 14.4 0.2 0.069 13.0 0.0 1.8 2 0 0 2 2 2 0 F-box-like Glyco_hydro_20 PF00728.22 KLO15933.1 - 9.1e-86 288.4 0.0 1.1e-85 288.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KLO15933.1 - 9e-14 52.3 0.0 2.5e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KLO15933.1 - 4.1e-07 30.8 0.0 1.2e-06 29.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 WD40 PF00400.32 KLO15934.1 - 1.7e-05 25.5 3.8 0.31 12.0 0.0 5.7 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO15934.1 - 8.1e-05 22.8 0.0 0.98 9.8 0.0 3.9 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KLO15935.1 - 2.5e-05 24.1 2.7 2.5e-05 24.1 2.7 2.7 3 1 0 3 3 3 1 F-box-like DUF3760 PF12586.8 KLO15935.1 - 0.064 13.4 0.1 0.2 11.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) F-box PF00646.33 KLO15935.1 - 0.15 12.0 7.8 0.035 14.0 2.5 2.8 2 1 0 2 2 2 0 F-box domain LRR_4 PF12799.7 KLO15936.1 - 0.0001 22.6 5.3 2.9 8.4 0.7 5.7 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO15936.1 - 0.0002 21.2 0.1 0.00047 20.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KLO15936.1 - 3.5 8.5 5.8 12 6.9 0.3 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 KLO15936.1 - 4 7.3 11.8 0.46 10.3 0.3 4.4 5 0 0 5 5 5 0 Leucine rich repeat Dynamin_N PF00350.23 KLO15937.1 - 2.7e-18 66.6 0.0 2.7e-18 66.6 0.0 2.8 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KLO15937.1 - 2.9e-13 49.9 0.0 9.7e-13 48.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KLO15937.1 - 1.1e-07 31.6 0.0 0.00016 21.3 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KLO15937.1 - 1.9e-05 24.7 1.1 0.11 12.4 0.2 2.9 2 1 1 3 3 3 2 RsgA GTPase cobW PF02492.19 KLO15937.1 - 0.00089 18.9 0.2 0.44 10.1 0.0 2.7 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KLO15937.1 - 0.0049 17.1 0.0 0.1 12.8 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KLO15937.1 - 0.0057 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arf PF00025.21 KLO15937.1 - 0.035 13.5 0.1 2 7.8 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family FeoB_N PF02421.18 KLO15937.1 - 0.037 13.6 0.0 0.42 10.1 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 KLO15937.1 - 0.05 12.9 0.4 0.096 11.9 0.0 1.6 2 0 0 2 2 2 0 Septin TsaE PF02367.17 KLO15937.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KLO15937.1 - 0.097 13.2 0.2 0.68 10.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 KLO15937.1 - 0.11 12.2 0.1 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Lipase_GDSL PF00657.22 KLO15938.1 - 1.4e-10 41.5 0.0 1.9e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KLO15938.1 - 1.3e-05 25.6 0.1 4.2e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family F-box-like PF12937.7 KLO15939.1 - 1.3e-06 28.2 0.2 4.1e-06 26.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO15939.1 - 3.7 8.1 12.6 19 5.8 1.2 5.7 6 2 1 7 7 7 0 Leucine Rich repeats (2 copies) MIP PF00230.20 KLO15940.1 - 4.5e-44 150.9 9.6 5.2e-44 150.6 9.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein F-box PF00646.33 KLO15941.1 - 5.9e-06 26.0 0.7 5.9e-06 26.0 0.7 2.2 2 0 0 2 2 2 1 F-box domain WD40 PF00400.32 KLO15941.1 - 3.5e-05 24.5 0.0 0.33 11.9 0.0 3.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO15941.1 - 0.0084 16.4 0.0 3.2 8.1 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KLO15941.1 - 0.016 15.1 0.4 0.056 13.3 0.1 2.0 2 0 0 2 2 2 0 F-box-like Acetate_kinase PF00871.17 KLO15942.1 - 2.3e-87 293.3 0.0 4.4e-87 292.3 0.0 1.4 1 1 0 1 1 1 1 Acetokinase family DUF1856 PF08983.10 KLO15943.1 - 1.6 9.0 6.9 1.4 9.2 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1856) HAT PF02184.16 KLO15944.1 - 2.1e-24 85.1 52.5 1.1e-06 28.5 2.7 12.9 13 1 0 13 13 13 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KLO15944.1 - 7.8e-18 63.6 41.1 0.0071 17.1 0.3 12.7 7 4 7 14 14 13 7 Tetratricopeptide repeat TPR_19 PF14559.6 KLO15944.1 - 2.1e-13 50.6 1.6 0.05 14.1 0.0 6.5 4 2 3 7 7 7 4 Tetratricopeptide repeat Suf PF05843.14 KLO15944.1 - 1.1e-11 45.2 19.9 0.00087 19.4 0.1 6.4 4 3 2 6 6 6 3 Suppressor of forked protein (Suf) TPR_17 PF13431.6 KLO15944.1 - 5.2e-10 39.0 3.1 0.00026 21.1 0.1 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO15944.1 - 1.3e-05 24.9 9.1 2.2 8.6 0.0 7.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KLO15944.1 - 0.00064 19.7 1.1 14 6.2 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KLO15944.1 - 0.00068 20.2 1.2 0.023 15.3 0.1 8.1 8 3 2 10 10 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 KLO15944.1 - 0.0024 17.2 23.6 0.5 9.5 0.2 5.5 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KLO15944.1 - 0.003 17.5 4.8 1.5 9.1 0.1 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KLO15944.1 - 0.0038 16.9 0.1 0.24 11.1 0.0 3.3 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.28 KLO15944.1 - 0.0042 16.8 3.3 31 4.6 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KLO15944.1 - 0.0066 16.5 1.5 1.4 9.0 0.0 4.1 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat U3_assoc_6 PF08640.11 KLO15944.1 - 0.08 13.0 10.1 1 9.4 0.2 5.2 4 3 2 7 7 7 0 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.6 KLO15944.1 - 0.2 12.0 13.1 5.2 7.4 0.2 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat RasGEF PF00617.19 KLO15945.1 - 2e-48 165.0 0.0 3.6e-48 164.1 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KLO15945.1 - 3.7e-19 68.9 0.0 8.7e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KLO15945.1 - 1.5e-13 50.4 0.0 2.7e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KLO15945.1 - 3.6e-12 45.8 0.0 7.8e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KLO15945.1 - 1.2e-11 44.1 0.0 2.4e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Focal_AT PF03623.13 KLO15945.1 - 0.001 19.1 1.4 0.26 11.3 0.2 2.6 2 0 0 2 2 2 2 Focal adhesion targeting region WD40 PF00400.32 KLO15946.1 - 0.0007 20.4 0.2 3.9 8.5 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box-like PF12937.7 KLO15946.1 - 0.02 14.8 0.1 0.061 13.2 0.1 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KLO15946.1 - 0.15 12.0 0.2 0.34 10.8 0.2 1.6 1 0 0 1 1 1 0 F-box domain ADH_zinc_N PF00107.26 KLO15947.1 - 3.4e-23 82.0 0.5 8.6e-23 80.7 0.3 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO15947.1 - 1e-13 52.5 0.1 1.8e-13 51.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO15947.1 - 1.5e-09 37.7 3.5 2.6e-08 33.7 0.1 3.0 3 1 1 4 4 4 2 Alcohol dehydrogenase GroES-like domain Hexapep_2 PF14602.6 KLO15947.1 - 0.07 12.9 2.3 0.34 10.7 0.1 2.6 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Trehalase PF01204.18 KLO15949.1 - 1.2e-110 370.8 1.8 3.2e-99 333.1 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 KLO15949.1 - 0.021 13.7 0.1 0.037 13.0 0.1 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase ELFV_dehydrog PF00208.21 KLO15950.1 - 2.1e-59 201.2 0.0 3e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KLO15950.1 - 1e-19 69.7 0.1 3e-14 51.6 0.1 2.3 3 0 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase Prenyltrans PF00432.21 KLO15951.1 - 2.9e-37 126.1 0.1 6.7e-10 38.5 0.2 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KLO15951.1 - 0.0012 18.1 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KLO15951.1 - 0.017 14.3 0.1 0.076 12.1 0.1 1.8 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 KLO15951.1 - 0.14 11.2 0.1 0.56 9.2 0.0 2.0 1 1 1 2 2 2 0 A-macroglobulin TED domain Peptidase_M43 PF05572.13 KLO15952.1 - 0.046 13.6 0.5 2.9 7.8 0.0 3.3 4 0 0 4 4 4 0 Pregnancy-associated plasma protein-A Filament_head PF04732.14 KLO15952.1 - 3.1 8.7 8.7 1.7 9.6 1.2 2.5 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Palm_thioest PF02089.15 KLO15953.1 - 0.00093 19.1 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KLO15953.1 - 0.0017 17.9 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 KLO15953.1 - 0.032 13.9 0.0 0.24 11.0 0.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold EamA PF00892.20 KLO15954.1 - 4.6e-22 78.7 34.0 1.1e-13 51.5 9.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 KLO15954.1 - 0.028 12.7 21.2 0.19 10.0 4.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Lipase_3 PF01764.25 KLO15955.1 - 1.2e-17 64.1 0.0 2.1e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KLO15955.1 - 0.0016 18.0 0.3 0.028 14.0 0.3 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) DUF900 PF05990.12 KLO15955.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) ACC_central PF08326.12 KLO15955.1 - 0.18 10.0 0.1 0.25 9.5 0.1 1.1 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region Mod_r PF07200.13 KLO15956.1 - 9.5e-44 149.0 4.8 1.1e-43 148.8 4.8 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein COG6 PF06419.11 KLO15956.1 - 0.0076 14.5 1.6 0.0092 14.2 1.6 1.2 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF3584 PF12128.8 KLO15956.1 - 0.014 13.0 2.3 0.019 12.5 2.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) F-box-like PF12937.7 KLO15957.1 - 1e-05 25.3 1.4 2.3e-05 24.2 1.4 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KLO15957.1 - 0.2 11.4 3.5 1.5 8.6 0.1 3.9 4 1 0 5 5 5 0 Leucine rich repeat Glyco_hydro_61 PF03443.14 KLO15958.1 - 3.9e-67 226.2 0.3 6.7e-67 225.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KLO15958.1 - 2.8e-12 46.4 4.3 7.2e-12 45.0 4.3 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain PLDc_N PF13396.6 KLO15959.1 - 3.8 7.5 10.8 0.058 13.3 2.0 2.7 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal NCA2 PF08637.10 KLO15963.1 - 3.2e-85 285.8 0.0 8.4e-85 284.4 0.0 1.6 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 MIP PF00230.20 KLO15964.1 - 8.4e-52 176.1 5.8 1e-51 175.9 5.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein EamA PF00892.20 KLO15964.1 - 7.8 6.7 14.9 0.14 12.3 1.9 3.2 3 1 0 3 3 3 0 EamA-like transporter family F-box-like PF12937.7 KLO15965.1 - 2.7e-07 30.4 0.1 8.6e-07 28.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like Sod_Cu PF00080.20 KLO15966.1 - 8.6e-48 162.1 1.7 1e-47 161.9 1.7 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) BppL_N PF18338.1 KLO15966.1 - 0.038 13.8 0.3 0.15 11.9 0.2 2.1 2 0 0 2 2 2 0 Lower baseplate protein N-terminal domain His_Phos_1 PF00300.22 KLO15967.1 - 3.2e-32 111.8 0.0 7.6e-32 110.6 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CH PF00307.31 KLO15968.1 - 3.2e-48 162.4 0.0 6.6e-25 87.4 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KLO15968.1 - 1.8e-17 63.1 0.0 7.5e-17 61.2 0.0 2.2 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KLO15968.1 - 1.5e-12 47.1 0.1 2e-08 34.0 0.0 2.8 2 1 0 2 2 2 2 CAMSAP CH domain EF-hand_7 PF13499.6 KLO15968.1 - 0.0023 18.3 0.2 0.014 15.9 0.2 2.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KLO15968.1 - 0.008 16.0 0.0 0.051 13.5 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KLO15968.1 - 0.038 13.5 0.1 0.21 11.2 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_14 PF17959.1 KLO15968.1 - 0.053 13.9 0.6 6.4 7.2 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain Mce4_CUP1 PF11887.8 KLO15968.1 - 0.057 12.9 1.5 0.32 10.4 0.2 2.1 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Baculo_PEP_C PF04513.12 KLO15968.1 - 0.11 12.5 0.2 0.59 10.2 0.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3581 PF12119.8 KLO15968.1 - 0.16 11.4 0.1 0.32 10.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) MscS_porin PF12795.7 KLO15968.1 - 0.4 10.2 7.1 0.87 9.1 7.1 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF3037 PF11236.8 KLO15968.1 - 0.65 10.4 3.0 3.4 8.1 0.0 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3037) Exonuc_VII_L PF02601.15 KLO15968.1 - 7.5 6.0 6.5 1.6 8.3 1.9 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit RSN1_7TM PF02714.15 KLO15969.1 - 3.7e-37 128.1 22.0 3.3e-35 121.7 22.0 2.4 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KLO15969.1 - 1.5e-22 80.7 0.0 9.8e-15 55.2 0.0 3.2 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KLO15969.1 - 3.1e-20 72.5 2.4 2.4e-19 69.6 2.1 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 KLO15969.1 - 0.053 13.3 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_25 PF13649.6 KLO15970.1 - 1.6e-05 25.5 0.0 0.0011 19.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain RCC_reductase PF06405.11 KLO15970.1 - 0.09 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) RasGEF PF00617.19 KLO15971.1 - 2.1e-15 57.4 0.6 4.4e-15 56.3 0.1 1.9 2 0 0 2 2 2 1 RasGEF domain DUF346 PF03984.13 KLO15971.1 - 0.061 13.1 1.5 0.13 12.0 1.5 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) Eaf7 PF07904.13 KLO15972.1 - 1.2e-15 57.8 0.0 2.5e-15 56.7 0.0 1.6 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Pkinase PF00069.25 KLO15973.1 - 6.9e-69 232.1 0.0 8.8e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO15973.1 - 6.4e-29 101.0 0.0 8.6e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KLO15973.1 - 5.1e-10 39.9 0.5 1.5e-09 38.4 0.5 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KLO15973.1 - 2.2e-07 30.2 0.1 3.8e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KLO15973.1 - 1.4e-06 27.9 0.0 3.9e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KLO15973.1 - 0.011 15.4 0.0 3.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KLO15973.1 - 0.021 14.4 0.1 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KLO15973.1 - 0.022 14.1 0.1 0.035 13.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BetaGal_dom4_5 PF13364.6 KLO15973.1 - 0.12 13.0 0.0 16 6.1 0.0 2.4 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain APH PF01636.23 KLO15973.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4504 PF14953.6 KLO15974.1 - 0.00035 20.1 0.0 0.0032 16.9 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) Pro_isomerase PF00160.21 KLO15975.1 - 8e-51 172.4 0.1 2.7e-50 170.7 0.1 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KLO15975.1 - 1.6e-08 35.0 1.6 0.0085 16.9 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO15975.1 - 0.057 13.7 0.0 13 6.2 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Motile_Sperm PF00635.26 KLO15976.1 - 2.5e-26 91.7 0.8 4.3e-26 90.9 0.2 1.6 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 KLO15976.1 - 0.0061 16.8 0.1 0.012 15.8 0.1 1.5 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 KLO15976.1 - 0.045 14.0 0.1 0.079 13.2 0.1 1.4 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF5001 PF16392.5 KLO15976.1 - 0.1 12.5 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Ig-like domain RICTOR_N PF14664.6 KLO15978.1 - 6.4e-114 380.8 0.7 1.3e-113 379.8 0.7 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KLO15978.1 - 4.7e-36 123.5 0.4 1.6e-34 118.6 0.2 2.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KLO15978.1 - 3.1e-35 120.1 0.3 8.1e-33 112.3 0.3 4.0 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KLO15978.1 - 1e-28 99.3 0.0 1.8e-25 89.0 0.0 4.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Cnd1 PF12717.7 KLO15978.1 - 0.003 17.6 0.3 0.015 15.3 0.1 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KLO15978.1 - 0.019 15.4 1.5 0.41 11.1 0.0 3.5 4 0 0 4 4 4 0 HEAT repeats HEAT PF02985.22 KLO15978.1 - 0.023 14.9 0.2 82 3.9 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat RTP1_C1 PF10363.9 KLO15978.1 - 0.14 12.3 0.2 1 9.6 0.1 2.6 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 ETC_C1_NDUFA4 PF04800.12 KLO15979.1 - 1.3e-37 128.0 0.4 7.4e-37 125.5 0.3 1.9 2 0 0 2 2 2 1 ETC complex I subunit conserved region TusA PF01206.17 KLO15979.1 - 0.095 12.5 0.0 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Sulfurtransferase TusA Rtt106_N PF18215.1 KLO15979.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain Zn_clus PF00172.18 KLO15980.1 - 0.017 15.2 10.5 0.099 12.8 10.2 2.1 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ephrin_rec_like PF07699.13 KLO15980.1 - 1.1 9.1 5.0 2.2 8.1 5.0 1.4 1 0 0 1 1 1 0 Putative ephrin-receptor like PSI_integrin PF17205.3 KLO15980.1 - 3.1 7.6 11.6 0.95 9.3 2.2 2.4 1 1 1 2 2 2 0 Integrin plexin domain Ribosomal_L22 PF00237.19 KLO15982.1 - 6.4e-37 125.9 0.0 9.1e-37 125.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Terpene_synth_C PF03936.16 KLO15983.1 - 0.0039 16.6 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Mito_carr PF00153.27 KLO15984.1 - 5.7e-40 135.2 5.0 2.3e-14 53.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MutS_V PF00488.21 KLO15985.1 - 5.7e-45 153.6 0.0 1.6e-44 152.2 0.0 1.7 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KLO15985.1 - 1.7e-30 106.7 0.1 5.6e-29 101.7 0.0 2.3 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KLO15985.1 - 0.029 14.7 0.0 0.088 13.2 0.0 1.9 1 0 0 1 1 1 0 MutS family domain IV DAP3 PF10236.9 KLO15985.1 - 0.055 12.6 0.8 0.69 9.0 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.6 KLO15985.1 - 0.093 12.8 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Band_7 PF01145.25 KLO15986.1 - 2.8e-24 86.1 1.7 4.3e-24 85.5 1.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family PQ-loop PF04193.14 KLO15987.1 - 7.4e-35 118.5 15.0 3.2e-20 71.7 1.1 2.8 3 0 0 3 3 3 2 PQ loop repeat DUF5090 PF17009.5 KLO15987.1 - 0.013 15.5 5.9 0.036 14.0 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) DUF4231 PF14015.6 KLO15987.1 - 0.064 13.7 0.3 0.66 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PelG PF16933.5 KLO15987.1 - 4.9 5.9 11.2 0.13 11.1 1.8 2.4 2 1 1 3 3 3 0 Putative exopolysaccharide Exporter (EPS-E) F-box-like PF12937.7 KLO15988.1 - 9.4e-11 41.4 0.1 5.5e-10 39.0 0.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 KLO15988.1 - 0.45 11.3 2.5 59 4.8 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 KLO15988.1 - 0.54 10.8 1.6 2.9e+02 2.1 0.2 4.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) zf-MYND PF01753.18 KLO15989.1 - 1.5e-08 34.5 14.3 2.7e-08 33.8 14.3 1.4 1 0 0 1 1 1 1 MYND finger ICA69 PF04629.14 KLO15989.1 - 0.23 11.7 0.1 0.55 10.5 0.0 1.6 2 0 0 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain G-patch PF01585.23 KLO15990.1 - 1e-05 25.3 1.3 0.00028 20.7 1.0 2.4 2 0 0 2 2 2 2 G-patch domain NopRA1 PF16201.5 KLO15991.1 - 0.023 14.3 0.0 1.3 8.5 0.0 2.6 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 Sld7_C PF18596.1 KLO15991.1 - 0.16 12.1 1.2 27 5.0 0.0 3.4 3 0 0 3 3 3 0 Sld7 C-terminal domain DUF5617 PF18493.1 KLO15991.1 - 0.2 11.8 0.5 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) KH_6 PF15985.5 KLO15992.1 - 2.1e-15 56.8 0.0 3.6e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KLO15992.1 - 8.1e-14 51.3 1.0 1.2e-13 50.8 0.4 1.6 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain zf-MYND PF01753.18 KLO15993.1 - 6.7e-08 32.5 17.8 1.6e-07 31.3 17.8 1.7 1 1 0 1 1 1 1 MYND finger AviRa PF11599.8 KLO15993.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_25 PF13649.6 KLO15994.1 - 1.3e-13 51.4 0.0 3.9e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO15994.1 - 2e-13 50.4 0.0 7.5e-13 48.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO15994.1 - 5.6e-12 45.8 0.0 8.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO15994.1 - 1.7e-10 40.7 0.0 4.3e-09 36.1 0.0 2.6 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KLO15994.1 - 5.7e-10 39.7 0.0 1.1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO15994.1 - 5.8e-07 30.2 0.0 1.6e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KLO15994.1 - 0.00031 20.5 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 KLO15994.1 - 0.008 15.7 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain CheR PF01739.18 KLO15994.1 - 0.011 15.3 0.0 1.5 8.2 0.0 2.2 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 KLO15994.1 - 0.017 14.6 0.0 2.8 7.4 0.0 2.7 3 0 0 3 3 3 0 Putative methyltransferase FtsJ PF01728.19 KLO15994.1 - 0.024 14.8 0.0 0.19 11.8 0.0 2.0 1 1 0 2 2 2 0 FtsJ-like methyltransferase UBD PF16455.5 KLO15994.1 - 0.057 13.7 0.1 9.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-binding domain Glyco_hydro_62 PF03664.13 KLO15994.1 - 0.081 12.2 0.0 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 62 Methyltransf_2 PF00891.18 KLO15994.1 - 0.097 12.0 0.0 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 O-methyltransferase domain ABC_membrane PF00664.23 KLO15998.1 - 7.1e-107 357.1 27.0 2.4e-56 191.4 7.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KLO15998.1 - 5.1e-67 224.6 0.1 1e-32 113.5 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KLO15998.1 - 3e-13 49.7 0.9 0.00028 20.4 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KLO15998.1 - 1.2e-06 27.7 0.1 0.012 14.4 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 KLO15998.1 - 3e-06 26.9 0.3 0.013 15.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KLO15998.1 - 1.4e-05 25.0 0.2 0.1 12.4 0.0 3.6 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KLO15998.1 - 5.6e-05 23.4 2.1 0.22 11.8 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KLO15998.1 - 0.00011 22.0 0.0 0.063 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KLO15998.1 - 0.00013 22.0 0.0 0.47 10.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 KLO15998.1 - 0.00015 21.1 0.0 0.4 9.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 KLO15998.1 - 0.00023 20.9 0.4 1.4 8.6 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.6 KLO15998.1 - 0.00025 20.7 0.0 0.16 11.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KLO15998.1 - 0.00032 21.1 6.1 0.18 12.2 0.1 3.3 2 2 1 3 3 3 2 AAA ATPase domain G-alpha PF00503.20 KLO15998.1 - 0.00042 19.6 0.0 0.28 10.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_23 PF13476.6 KLO15998.1 - 0.001 19.6 0.0 2.6 8.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KLO15998.1 - 0.0033 17.6 2.5 1.9 8.8 0.3 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 KLO15998.1 - 0.0035 17.5 1.8 1.4 9.0 0.1 3.3 3 1 0 3 3 3 1 Helicase HerA, central domain AAA_18 PF13238.6 KLO15998.1 - 0.0047 17.5 0.0 3.5 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KLO15998.1 - 0.0056 17.1 3.5 7.4 7.0 0.7 4.2 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KLO15998.1 - 0.0069 16.4 0.5 7.1 6.6 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) PRK PF00485.18 KLO15998.1 - 0.015 15.1 0.0 1.3 8.7 0.0 2.8 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 KLO15998.1 - 0.016 14.7 0.0 3 7.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 KLO15998.1 - 0.017 15.3 0.0 7.6 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KLO15998.1 - 0.023 14.6 0.1 0.93 9.4 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.13 KLO15998.1 - 0.035 13.3 0.0 7.8 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KLO15998.1 - 0.044 14.0 4.2 1.4 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KLO15998.1 - 0.049 12.8 0.0 5.5 6.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 KLO15998.1 - 0.061 13.7 0.0 8.3 6.9 0.0 3.1 3 0 0 3 3 2 0 RNA helicase MMR_HSR1 PF01926.23 KLO15998.1 - 0.066 13.3 0.1 19 5.4 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 KLO15998.1 - 0.1 12.0 0.0 7.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KLO15998.1 - 0.15 11.8 0.4 20 4.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KLO15998.1 - 0.19 11.6 0.1 1.5 8.7 0.0 2.2 3 0 0 3 3 2 0 Rad17 P-loop domain MT0933_antitox PF14013.6 KLO15998.1 - 1.2 9.5 4.8 12 6.2 0.3 2.8 2 0 0 2 2 2 0 MT0933-like antitoxin protein AAA_17 PF13207.6 KLO15998.1 - 4.8 7.6 4.9 44 4.5 0.0 3.4 4 0 0 4 4 2 0 AAA domain Cofilin_ADF PF00241.20 KLO15999.1 - 1.6e-32 111.9 0.4 1.8e-32 111.7 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1310 PF07006.11 KLO15999.1 - 0.037 14.0 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) zf-AN1 PF01428.16 KLO16000.1 - 5.4e-20 71.3 28.3 9.4e-11 41.7 9.9 2.5 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KLO16000.1 - 0.023 15.0 5.7 0.023 15.0 5.7 2.8 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain zinc_ribbon_6 PF14599.6 KLO16000.1 - 1.4 9.0 17.6 0.045 13.8 4.7 2.7 2 1 1 3 3 3 0 Zinc-ribbon DUF530 PF04409.12 KLO16000.1 - 2.9 6.2 6.5 2.8 6.2 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF530) IBR PF01485.21 KLO16000.1 - 7 7.0 25.6 0.23 11.7 6.3 2.9 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain Porin_3 PF01459.22 KLO16001.1 - 1.6e-58 198.3 5.3 2.5e-58 197.7 5.3 1.3 1 1 0 1 1 1 1 Eukaryotic porin SAPS PF04499.15 KLO16002.1 - 1 8.1 4.9 1 8.1 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Lin-8 PF03353.15 KLO16002.1 - 3.1 7.3 8.3 4.2 6.8 8.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 KLO16002.1 - 5.6 5.0 19.8 6.7 4.8 19.8 1.0 1 0 0 1 1 1 0 Nop14-like family PH PF00169.29 KLO16003.1 - 0.049 14.1 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 PH domain peroxidase PF00141.23 KLO16004.1 - 8.4e-28 97.6 0.0 1.4e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KLO16004.1 - 4.4e-27 93.8 3.5 8.1e-27 93.0 2.4 2.0 2 0 0 2 2 2 1 Fungal peroxidase extension region peroxidase PF00141.23 KLO16005.1 - 6.6e-29 101.2 0.1 1.4e-28 100.2 0.0 1.6 1 1 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KLO16005.1 - 6.6e-27 93.3 2.9 1.3e-26 92.3 1.6 2.1 2 0 0 2 2 2 1 Fungal peroxidase extension region PIRT PF15099.6 KLO16006.1 - 0.027 14.1 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family TRP PF06011.12 KLO16006.1 - 0.03 13.1 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel peroxidase PF00141.23 KLO16007.1 - 5.4e-27 95.0 0.0 6.9e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KLO16007.1 - 9.1e-19 67.2 0.2 2.2e-18 65.9 0.2 1.7 1 0 0 1 1 1 1 Fungal peroxidase extension region HeH PF12949.7 KLO16008.1 - 7.7e-05 22.3 0.2 0.0002 21.0 0.2 1.7 1 0 0 1 1 1 1 HeH/LEM domain Tho1_MOS11_C PF18592.1 KLO16008.1 - 0.00025 20.8 5.9 11 5.9 3.0 4.3 3 1 0 3 3 3 3 Tho1/MOS11 C-terminal domain Rho_N PF07498.12 KLO16008.1 - 0.28 11.2 1.7 0.51 10.3 1.7 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain NOG1_N PF17835.1 KLO16009.1 - 1.2e-48 165.1 2.0 1.2e-48 165.1 0.3 1.9 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KLO16009.1 - 1.8e-28 98.2 3.2 4.6e-28 97.0 3.2 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KLO16009.1 - 7.5e-27 92.9 0.1 1.5e-26 91.9 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KLO16009.1 - 2.5e-17 63.0 0.0 6.1e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KLO16009.1 - 1.5e-09 37.6 0.0 3.3e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KLO16009.1 - 0.0002 21.3 0.1 0.85 9.5 0.0 2.9 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KLO16009.1 - 0.0085 15.6 0.1 0.11 12.0 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KLO16009.1 - 0.011 15.2 0.1 0.73 9.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein Dynamin_N PF00350.23 KLO16009.1 - 0.012 15.7 1.3 1.8 8.6 0.0 3.0 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.6 KLO16009.1 - 0.024 15.0 0.5 0.39 11.1 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 KLO16009.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Sushi_2 PF09014.10 KLO16009.1 - 0.045 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain AIG1 PF04548.16 KLO16009.1 - 0.066 12.5 0.0 0.21 10.9 0.0 2.0 1 0 0 1 1 1 0 AIG1 family Peptidase_M24 PF00557.24 KLO16010.1 - 1.2e-43 149.3 0.0 1.7e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 KLO16010.1 - 5.1e-40 137.2 0.0 1.7e-39 135.5 0.0 2.0 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 KLO16010.1 - 7.3e-21 75.2 0.5 4.2e-19 69.5 0.1 2.8 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KLO16010.1 - 4e-18 65.2 0.3 9.9e-18 64.0 0.3 1.7 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 stn_TNFRSF12A PF12191.8 KLO16013.1 - 0.012 15.8 0.7 3 8.1 0.0 2.8 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain X PF00739.19 KLO16013.1 - 1.9 8.6 5.7 6.2 6.9 0.1 3.0 2 1 0 2 2 2 0 Trans-activation protein X zf-MYND PF01753.18 KLO16014.1 - 1.8e-08 34.4 8.9 4e-08 33.2 8.9 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KLO16014.1 - 0.17 12.2 4.7 0.4 11.0 4.7 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PIEZO PF15917.5 KLO16015.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.4 2 0 0 2 2 2 0 Piezo zf-RING_2 PF13639.6 KLO16016.1 - 1.3e-06 28.7 9.2 2.5e-06 27.7 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KLO16016.1 - 1.7e-05 24.5 8.3 3.3e-05 23.6 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO16016.1 - 0.00075 19.4 9.7 0.0014 18.5 9.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KLO16016.1 - 0.0011 18.8 9.7 0.0023 17.8 9.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 KLO16016.1 - 0.0066 16.4 3.5 0.013 15.5 3.5 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 KLO16016.1 - 0.0086 15.9 9.9 0.016 15.0 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO16016.1 - 0.011 15.8 9.4 0.028 14.5 9.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KLO16016.1 - 0.015 15.1 12.9 0.15 12.0 12.7 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.21 KLO16016.1 - 0.026 14.7 1.5 0.063 13.4 1.5 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_4 PF14570.6 KLO16016.1 - 0.056 13.2 7.4 0.12 12.2 7.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KLO16016.1 - 0.29 11.1 6.1 0.64 9.9 6.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 KLO16016.1 - 0.67 9.6 5.8 1.2 8.9 5.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 KLO16016.1 - 1.2 9.3 6.1 2.3 8.4 6.1 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 CorA PF01544.18 KLO16017.1 - 5.8e-30 104.6 5.1 4.2e-26 91.9 1.9 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Ribosomal_60s PF00428.19 KLO16021.1 - 0.22 12.1 7.8 0.53 10.9 7.8 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Utp14 PF04615.13 KLO16021.1 - 0.49 8.9 2.6 0.63 8.5 2.6 1.0 1 0 0 1 1 1 0 Utp14 protein Cwf_Cwc_15 PF04889.12 KLO16021.1 - 0.61 9.8 8.7 0.87 9.3 8.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KLO16021.1 - 3 5.9 4.8 3.9 5.6 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KLO16021.1 - 3.5 5.6 8.5 4.6 5.2 8.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 KLO16021.1 - 5.7 7.4 11.6 10 6.6 11.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KLO16021.1 - 9.4 5.5 10.5 5.4 6.3 8.0 1.7 2 0 0 2 2 2 0 NOA36 protein F-box-like PF12937.7 KLO16023.1 - 5.5e-07 29.4 0.8 4e-06 26.6 0.5 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO16023.1 - 1.2 9.1 7.4 1.3 9.0 2.0 3.3 2 1 0 2 2 2 0 F-box domain Stevor PF17410.2 KLO16024.1 - 0.18 11.3 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame LapA_dom PF06305.11 KLO16024.1 - 5.6 6.9 5.3 1.7 8.5 1.5 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Laminin_II PF06009.12 KLO16025.1 - 0.011 15.8 2.6 0.017 15.1 2.6 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF1845 PF08900.11 KLO16025.1 - 0.029 14.1 0.2 0.047 13.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) DUF2570 PF10828.8 KLO16025.1 - 0.25 11.2 2.9 0.39 10.6 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Cytochrom_B561 PF03188.16 KLO16026.1 - 7.3e-10 39.1 0.2 1.4e-09 38.2 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 KLO16026.1 - 7.3e-08 32.3 2.6 2.7e-06 27.2 2.6 2.5 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF4784 PF16023.5 KLO16026.1 - 0.14 11.1 0.1 0.23 10.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4784) DOMON PF03351.17 KLO16026.1 - 0.15 12.3 0.2 0.34 11.1 0.2 1.7 1 1 0 1 1 1 0 DOMON domain DUF2427 PF10348.9 KLO16026.1 - 0.92 9.3 4.3 0.79 9.5 1.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) API5 PF05918.11 KLO16028.1 - 1.2e-23 83.7 0.0 1.5e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 KLO16028.1 - 0.0012 19.1 0.3 0.0064 16.9 0.2 2.1 1 1 0 2 2 2 1 HEAT repeats Rab_bind PF16704.5 KLO16028.1 - 0.038 14.0 0.4 0.084 12.9 0.4 1.6 1 0 0 1 1 1 0 Rab binding domain Adaptin_N PF01602.20 KLO16028.1 - 0.066 11.8 0.1 0.088 11.3 0.1 1.2 1 0 0 1 1 1 0 Adaptin N terminal region FAD_binding_3 PF01494.19 KLO16029.1 - 6.3e-21 75.0 0.0 1.2e-20 74.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KLO16029.1 - 5.7e-09 35.3 4.2 0.00099 18.1 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KLO16029.1 - 2.2e-07 30.3 0.6 0.01 14.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KLO16029.1 - 3.3e-07 30.4 0.5 8.2e-07 29.2 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO16029.1 - 1e-05 25.0 1.2 0.0013 18.0 0.7 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KLO16029.1 - 0.00018 20.7 2.0 0.00033 19.9 2.0 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KLO16029.1 - 0.00075 18.9 1.7 0.23 10.7 0.1 2.7 3 1 0 3 3 3 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KLO16029.1 - 0.0018 17.1 1.2 0.0031 16.3 1.2 1.4 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KLO16029.1 - 0.0023 17.6 5.2 0.0052 16.4 4.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KLO16029.1 - 0.0065 15.7 0.4 0.011 15.0 0.4 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KLO16029.1 - 0.011 14.9 0.8 0.016 14.3 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KLO16029.1 - 0.019 15.5 1.1 0.043 14.4 0.2 2.1 3 0 0 3 3 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KLO16029.1 - 0.02 14.3 1.8 0.041 13.2 1.8 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KLO16029.1 - 0.069 13.1 0.4 18 5.3 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding SE PF08491.10 KLO16029.1 - 0.075 12.1 0.0 0.3 10.1 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase BRX PF08381.11 KLO16029.1 - 0.16 11.4 1.4 0.33 10.3 1.4 1.5 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Pyr_redox_3 PF13738.6 KLO16029.1 - 0.81 8.9 3.6 1.7 7.8 3.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Asp PF00026.23 KLO16030.1 - 5.5e-67 226.4 2.0 6.5e-67 226.2 2.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO16030.1 - 2.1e-12 47.7 2.2 3.7e-08 33.8 0.2 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KLO16030.1 - 0.00085 19.9 1.3 0.1 13.2 0.3 2.9 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 KLO16030.1 - 0.064 13.0 0.0 6.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KLO16030.1 - 0.082 13.5 1.3 0.13 12.9 0.1 1.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Amidohydro_1 PF01979.20 KLO16031.1 - 4.6e-13 49.2 0.3 4.7e-10 39.3 0.0 3.3 3 1 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.11 KLO16031.1 - 5.9e-12 45.8 1.2 2.3e-07 30.6 0.1 3.0 3 0 0 3 3 3 2 Amidohydrolase family Pkinase PF00069.25 KLO16032.1 - 1.5e-71 240.9 0.0 1.9e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16032.1 - 1.2e-36 126.4 0.0 1.6e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KLO16032.1 - 2.4e-16 59.8 0.9 4.5e-16 59.0 0.9 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KLO16032.1 - 4.3e-06 26.3 0.0 1.6e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KLO16032.1 - 4.7e-06 26.7 0.1 0.029 14.3 0.0 3.5 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 KLO16032.1 - 1.6e-05 24.4 0.1 2.6e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 KLO16032.1 - 2.5e-05 24.5 0.0 5.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 KLO16032.1 - 0.046 12.5 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KLO16032.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FHA_2 PF17913.1 KLO16032.1 - 0.15 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 FHA domain Acyltransferase PF01553.21 KLO16033.1 - 4.3e-14 52.3 0.0 7.6e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase SR-25 PF10500.9 KLO16033.1 - 0.0034 17.0 2.0 0.0057 16.3 2.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein NAM-associated PF14303.6 KLO16033.1 - 0.22 12.2 1.7 0.42 11.3 1.7 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain BTB PF00651.31 KLO16034.1 - 0.0027 17.9 0.0 0.0093 16.2 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain AXH PF08517.12 KLO16037.1 - 0.54 10.8 1.9 1.9 9.1 0.6 2.3 2 1 0 2 2 2 0 Ataxin-1 and HBP1 module (AXH) F-box-like PF12937.7 KLO16038.1 - 0.06 13.3 0.1 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 F-box-like Phage_holin_3_7 PF05449.11 KLO16039.1 - 0.54 10.3 4.3 0.35 10.9 1.2 2.4 2 0 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 Hist_deacetyl PF00850.19 KLO16042.1 - 6e-84 282.1 0.0 1e-83 281.3 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 KLO16042.1 - 2.2e-30 105.7 0.0 3.5e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Fungal_trans PF04082.18 KLO16043.1 - 1.1e-07 31.2 0.1 2.5e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO16043.1 - 2.1e-07 31.0 12.0 3.4e-07 30.3 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.18 KLO16043.1 - 0.014 14.9 2.0 0.035 13.6 2.0 1.7 1 0 0 1 1 1 0 Copper fist DNA binding domain Lzipper-MIP1 PF14389.6 KLO16043.1 - 0.17 12.2 0.4 0.87 9.9 0.0 2.3 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 ABC_tran_CTD PF16326.5 KLO16043.1 - 0.28 11.5 0.5 5.9 7.2 0.2 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain TRP PF06011.12 KLO16045.1 - 1.2e-77 261.5 17.2 1.5e-77 261.2 17.2 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KLO16045.1 - 9.7e-27 94.0 0.1 1.4e-26 93.5 0.1 1.2 1 0 0 1 1 1 1 ML-like domain Adeno_E3_CR2 PF02439.15 KLO16045.1 - 0.76 9.6 6.8 2.2 8.1 6.8 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 YrhC PF14143.6 KLO16045.1 - 6.7 6.9 13.9 1.8 8.7 0.4 3.4 4 0 0 4 4 4 0 YrhC-like protein zf-MYND PF01753.18 KLO16048.1 - 2e-10 40.6 14.3 4.8e-10 39.4 14.3 1.7 1 0 0 1 1 1 1 MYND finger Citrate_synt PF00285.21 KLO16049.1 - 0.18 10.8 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain HMG_box PF00505.19 KLO16050.1 - 1e-07 32.3 2.6 2.6e-07 31.0 2.6 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO16050.1 - 5.3e-07 30.1 2.2 1.6e-06 28.6 2.2 1.8 1 0 0 1 1 1 1 HMG-box domain RFX1_trans_act PF04589.13 KLO16050.1 - 0.0011 19.2 1.3 0.0033 17.6 1.3 1.8 1 0 0 1 1 1 1 RFX1 transcription activation region MRPL52 PF18699.1 KLO16050.1 - 1 9.6 5.0 9.4 6.5 0.4 2.4 2 0 0 2 2 2 0 Mitoribosomal protein mL52 SET PF00856.28 KLO16052.1 - 3.2e-21 76.5 0.2 1.4e-20 74.4 0.1 2.1 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 KLO16052.1 - 5.8e-19 68.8 1.6 5.8e-19 68.8 1.6 2.5 2 1 0 2 2 2 1 Pre-SET motif OSCP PF00213.18 KLO16053.1 - 4.4e-40 137.6 1.1 5e-40 137.4 1.1 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit NTP_transf_3 PF12804.7 KLO16055.1 - 1.4e-08 35.2 0.0 2.2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KLO16055.1 - 8e-07 28.5 1.5 0.00058 19.5 0.4 2.6 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KLO16055.1 - 2.2e-06 27.4 0.0 3.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase RNA_pol_3_Rpc31 PF11705.8 KLO16055.1 - 0.023 14.9 11.0 0.04 14.2 11.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4954 PF16314.5 KLO16055.1 - 0.033 12.3 0.2 0.045 11.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KLO16055.1 - 0.051 12.5 0.7 0.14 11.1 0.7 1.6 1 1 0 1 1 1 0 L-fucokinase NOA36 PF06524.12 KLO16055.1 - 1.3 8.3 17.6 1.9 7.7 17.6 1.2 1 0 0 1 1 1 0 NOA36 protein MgsA_C PF12002.8 KLO16056.1 - 5.2e-59 198.9 0.0 8.6e-59 198.2 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KLO16056.1 - 2.1e-19 69.6 0.2 5.1e-19 68.4 0.2 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KLO16056.1 - 9.8e-16 58.4 0.0 4.2e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KLO16056.1 - 1.4e-15 57.4 0.0 2.8e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KLO16056.1 - 1.3e-07 32.2 0.3 0.003 17.9 0.0 3.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KLO16056.1 - 1.4e-07 31.5 0.0 1.6e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KLO16056.1 - 6.4e-06 26.0 0.0 0.00068 19.4 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KLO16056.1 - 9.4e-06 25.2 0.0 0.083 12.3 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KLO16056.1 - 1.6e-05 25.2 0.2 0.00047 20.4 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 KLO16056.1 - 0.00011 22.2 0.0 0.00028 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KLO16056.1 - 0.00018 21.6 0.0 0.0005 20.2 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 KLO16056.1 - 0.00039 21.0 0.1 0.00097 19.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KLO16056.1 - 0.00062 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KLO16056.1 - 0.0015 18.7 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KLO16056.1 - 0.0031 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KLO16056.1 - 0.0042 17.4 0.0 0.014 15.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.14 KLO16056.1 - 0.014 15.5 0.0 0.048 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 KLO16056.1 - 0.015 15.8 0.0 0.05 14.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 KLO16056.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KLO16056.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KLO16056.1 - 0.076 12.4 0.0 5.4 6.4 0.0 3.0 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KLO16056.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.15 KLO16056.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 KLO16056.1 - 0.14 11.3 0.0 0.61 9.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KLO16056.1 - 0.14 12.0 0.1 3.4 7.5 0.1 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KLO16056.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KLO16056.1 - 0.15 11.9 0.0 0.73 9.7 0.0 2.0 1 1 1 2 2 2 0 RsgA GTPase RAP1 PF07218.11 KLO16056.1 - 0.32 9.2 1.6 0.62 8.3 1.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CSS-motif PF12792.7 KLO16058.1 - 0.14 11.6 0.1 0.2 11.1 0.1 1.4 1 1 0 1 1 1 0 CSS motif domain associated with EAL CRAL_TRIO PF00650.20 KLO16059.1 - 1.6e-09 37.6 0.0 2.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CYYR1 PF10873.8 KLO16060.1 - 0.00031 21.2 0.5 0.0004 20.9 0.5 1.2 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 LEP503 PF15221.6 KLO16060.1 - 0.016 15.5 0.2 0.02 15.2 0.2 1.2 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 EphA2_TM PF14575.6 KLO16060.1 - 0.023 15.5 0.5 0.082 13.8 0.2 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 KLO16060.1 - 0.045 13.9 0.1 0.058 13.5 0.1 1.2 1 0 0 1 1 1 0 Podoplanin Shisa PF13908.6 KLO16060.1 - 0.051 13.8 0.1 0.069 13.4 0.1 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2207 PF09972.9 KLO16060.1 - 0.088 11.6 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Amnionless PF14828.6 KLO16060.1 - 0.16 10.8 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless Mid2 PF04478.12 KLO16060.1 - 0.16 11.8 0.1 0.19 11.6 0.1 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Insulin_TMD PF17870.1 KLO16060.1 - 0.24 11.5 1.7 0.37 10.9 0.2 1.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment EVC2_like PF12297.8 KLO16060.1 - 0.28 9.8 0.1 0.27 9.9 0.1 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF2062 PF09835.9 KLO16060.1 - 0.31 10.9 3.4 0.5 10.2 3.4 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF347 PF03988.12 KLO16060.1 - 0.93 9.7 5.5 2.6 8.3 2.1 2.4 2 1 0 2 2 2 0 Repeat of Unknown Function (DUF347) DUF2474 PF10617.9 KLO16060.1 - 2.3 8.2 5.4 0.58 10.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) Syndecan PF01034.20 KLO16060.1 - 4.5 7.3 6.0 0.63 10.0 2.0 1.6 2 0 0 2 2 2 0 Syndecan domain FAM163 PF15069.6 KLO16060.1 - 5.2 7.5 6.3 7.9 6.9 6.3 1.3 1 0 0 1 1 1 0 FAM163 family Peptidase_C15 PF01470.17 KLO16061.1 - 0.00029 21.1 0.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 2 Pyroglutamyl peptidase Acyl-CoA_dh_1 PF00441.24 KLO16062.1 - 1.4e-29 103.2 0.1 1.9e-29 102.8 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KLO16062.1 - 4.2e-24 85.4 0.0 8.6e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KLO16062.1 - 3.5e-21 75.2 0.0 6.2e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KLO16062.1 - 1.5e-05 25.3 0.0 2.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MOZ_SAS PF01853.18 KLO16063.1 - 0.17 11.5 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 MOZ/SAS family OPT PF03169.15 KLO16064.1 - 1.6e-147 492.8 40.7 1.9e-147 492.6 40.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Holin_SPP1 PF04688.13 KLO16064.1 - 2.3 8.4 4.8 9.4 6.5 0.2 2.8 2 0 0 2 2 2 0 SPP1 phage holin OPT PF03169.15 KLO16066.1 - 5.9e-151 504.2 38.5 6.7e-151 504.0 38.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2062 PF09835.9 KLO16066.1 - 2.8 7.8 14.4 0.027 14.3 2.1 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) Fungal_trans PF04082.18 KLO16068.1 - 1.4e-12 47.2 0.0 1.1e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO16068.1 - 1.1e-07 31.8 9.0 1.7e-07 31.2 9.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KLO16069.1 - 1.4e-12 47.2 0.0 3.4e-12 45.9 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO16069.1 - 8.7e-08 32.2 10.6 1.9e-07 31.1 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 KLO16071.1 - 7.1e-23 81.3 0.0 6.5e-22 78.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO16071.1 - 1.4e-12 48.0 0.2 4.6e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO16071.1 - 0.00022 20.6 0.0 0.00049 19.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO16071.1 - 0.00098 18.8 1.5 1.3 8.6 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KLO16071.1 - 0.16 11.1 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KLO16071.1 - 0.18 10.6 0.1 28 3.4 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KLO16071.1 - 0.26 11.3 0.7 3.7 7.5 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KLO16071.1 - 0.34 11.2 1.9 18 5.6 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain F-box-like PF12937.7 KLO16072.1 - 2.6e-06 27.2 0.2 2.9e-05 23.9 0.2 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO16072.1 - 0.038 14.4 0.9 24 5.5 0.1 5.0 4 2 1 6 6 6 0 Leucine Rich repeats (2 copies) Ribosomal_S2 PF00318.20 KLO16073.1 - 1.9e-27 95.9 0.1 6.9e-15 54.9 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KLO16073.1 - 5e-09 37.4 11.8 1.1e-08 36.3 11.8 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus DUF4965 PF16335.5 KLO16074.1 - 1.2e-48 165.0 0.7 2.5e-48 164.0 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KLO16074.1 - 2.6e-37 128.8 0.1 4e-37 128.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KLO16074.1 - 1.6e-16 61.2 0.0 4.4e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO16074.1 - 2.5e-05 23.7 0.0 6.9e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) LapA_dom PF06305.11 KLO16075.1 - 0.011 15.6 0.8 0.017 14.9 0.8 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF872 PF05915.12 KLO16075.1 - 0.053 13.7 0.1 0.073 13.2 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF4381 PF14316.6 KLO16075.1 - 0.081 13.2 0.3 0.13 12.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CbtA PF09490.10 KLO16075.1 - 0.092 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) CD34_antigen PF06365.12 KLO16075.1 - 0.12 12.0 0.1 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family BatD PF13584.6 KLO16075.1 - 0.16 10.7 0.1 0.22 10.3 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4965 PF16335.5 KLO16076.1 - 7.8e-47 159.1 1.3 1.2e-46 158.5 0.1 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KLO16076.1 - 5.2e-38 131.1 1.9 1.2e-37 130.0 1.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KLO16076.1 - 4e-37 128.2 0.4 7.6e-37 127.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO16076.1 - 0.0068 15.9 0.5 0.065 12.8 0.5 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4964) Orf78 PF06024.12 KLO16076.1 - 0.2 12.0 0.3 0.4 11.0 0.3 1.5 1 0 0 1 1 1 0 Orf78 (ac78) YajC PF02699.15 KLO16076.1 - 0.36 10.7 1.0 0.81 9.6 1.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit SRTM1 PF15872.5 KLO16076.1 - 7.1 6.8 9.7 0.26 11.4 0.4 3.1 3 0 0 3 3 3 0 Serine-rich and transmembrane domain-containing protein 1 SHMT PF00464.19 KLO16079.1 - 7.4e-173 574.7 0.0 8.7e-173 574.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KLO16079.1 - 0.0044 16.3 0.0 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase Git3 PF11710.8 KLO16083.1 - 1.9e-07 31.1 6.3 4.1e-07 30.0 6.3 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_2 PF00002.24 KLO16083.1 - 0.0085 15.4 1.7 0.014 14.7 1.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KLO16083.1 - 0.024 13.7 1.3 0.042 13.0 1.3 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor TPPK_C PF12555.8 KLO16083.1 - 4.6 7.4 8.1 2.7 8.1 2.4 2.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal cpYpsA PF12694.7 KLO16087.1 - 0.1 12.4 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family F-box PF00646.33 KLO16088.1 - 0.00099 18.9 0.2 0.0023 17.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO16088.1 - 0.0042 17.0 0.1 0.0093 15.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KLO16088.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 F-box NAD_binding_4 PF07993.12 KLO16090.1 - 8.2e-70 234.9 0.0 3.6e-69 232.8 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 KLO16090.1 - 1.3e-67 228.3 0.0 2.2e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KLO16090.1 - 3.8e-12 46.4 0.0 1e-11 45.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 KLO16090.1 - 2.3e-09 36.5 0.0 1e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 Condensation domain Epimerase PF01370.21 KLO16090.1 - 6.1e-08 32.4 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KLO16090.1 - 2.1e-05 25.4 0.0 0.00018 22.4 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 KLO16090.1 - 0.0009 18.3 0.0 0.0033 16.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Metallophos_2 PF12850.7 KLO16092.1 - 2.8e-16 60.1 0.0 4.2e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KLO16092.1 - 5.5e-07 30.3 0.4 0.013 16.0 0.1 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Phage_P2_GpU PF06995.11 KLO16092.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage P2 GpU UPF0203 PF05254.12 KLO16093.1 - 5.4e-26 90.6 2.1 6.4e-26 90.4 2.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 KLO16093.1 - 0.0013 18.9 4.7 0.48 10.7 0.2 2.2 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 KLO16093.1 - 0.056 13.8 1.0 1.2 9.6 0.3 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Methyltrn_RNA_2 PF04013.12 KLO16093.1 - 0.058 13.1 0.0 0.072 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase Arginosuc_synth PF00764.19 KLO16093.1 - 0.071 12.4 0.0 0.086 12.1 0.0 1.0 1 0 0 1 1 1 0 Arginosuccinate synthase Pet191_N PF10203.9 KLO16093.1 - 0.098 13.0 1.3 4.2 7.7 0.4 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 ABC_membrane_2 PF06472.15 KLO16094.1 - 1.5e-76 257.4 0.2 2.1e-76 256.9 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KLO16094.1 - 3e-13 50.5 0.0 7.7e-13 49.1 0.0 1.7 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 KLO16094.1 - 0.015 15.2 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KLO16094.1 - 0.05 14.0 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KLO16094.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KLO16094.1 - 0.18 11.5 0.1 0.75 9.5 0.1 1.9 1 1 1 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF3395 PF11875.8 KLO16096.1 - 2.4e-29 102.2 0.3 8.7e-29 100.4 0.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KLO16096.1 - 8.7e-16 57.8 1.4 1.8e-15 56.8 1.4 1.6 1 0 0 1 1 1 1 DnaJ domain Gti1_Pac2 PF09729.9 KLO16098.1 - 2.6e-29 102.6 0.1 2.2e-26 93.0 0.2 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family ADH_N PF08240.12 KLO16102.1 - 1.2e-31 108.8 3.1 2e-31 108.1 3.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO16102.1 - 2.3e-13 50.2 0.0 5.6e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KLO16102.1 - 1.5e-12 47.5 0.0 2.5e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KLO16102.1 - 7.2e-08 33.6 0.1 1.7e-07 32.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KLO16102.1 - 0.0004 19.7 0.7 0.00058 19.2 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_3 PF03447.16 KLO16102.1 - 0.006 17.2 0.0 0.041 14.5 0.0 2.1 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Staph_opine_DH PF10100.9 KLO16102.1 - 0.19 10.4 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase Shikimate_DH PF01488.20 KLO16102.1 - 0.2 11.7 0.2 0.69 10.0 0.1 2.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase His_Phos_2 PF00328.22 KLO16103.1 - 9e-17 61.5 0.0 3.3e-15 56.3 0.0 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Rad60-SLD_2 PF13881.6 KLO16103.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Sec5 PF15469.6 KLO16105.1 - 3.3e-57 193.4 0.5 1.1e-56 191.7 0.3 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec5 CK2S PF15011.6 KLO16105.1 - 0.015 15.2 0.0 0.057 13.3 0.0 2.0 1 0 0 1 1 1 0 Casein Kinase 2 substrate COG2 PF06148.11 KLO16105.1 - 0.25 11.4 4.2 0.73 9.9 0.1 3.1 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Dioxygenase_C PF00775.21 KLO16106.1 - 3.8e-38 130.7 0.0 6e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KLO16106.1 - 1.1e-18 66.8 0.0 2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KLO16106.1 - 0.046 14.0 1.3 0.24 11.7 0.7 2.4 2 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain TauD PF02668.16 KLO16107.1 - 2.7e-61 207.7 0.2 3.4e-61 207.4 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family JTB PF05439.12 KLO16108.1 - 0.003 17.6 0.3 0.0085 16.1 0.0 1.7 2 0 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) zf-NF-X1 PF01422.17 KLO16108.1 - 1.1 9.4 6.1 2.9 8.1 6.1 1.8 1 0 0 1 1 1 0 NF-X1 type zinc finger SRP19 PF01922.17 KLO16109.1 - 3.4e-24 85.6 0.0 5.2e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein SSP160 PF06933.11 KLO16109.1 - 0.028 12.6 1.4 0.037 12.2 1.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HNF-1_N PF04814.13 KLO16109.1 - 0.053 14.1 0.3 0.096 13.3 0.3 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus RAP1 PF07218.11 KLO16109.1 - 1.9 6.7 8.4 2.6 6.2 8.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Helitron_like_N PF14214.6 KLO16110.1 - 1.9e-37 129.4 0.1 1.7e-36 126.3 0.1 2.2 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KLO16110.1 - 0.033 13.3 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) COesterase PF00135.28 KLO16112.1 - 3.9e-60 204.2 0.0 3.4e-55 187.9 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO16112.1 - 0.0013 18.6 0.6 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold RPN1_RPN2_N PF17781.1 KLO16113.1 - 7.8e-115 383.5 0.3 1.4e-114 382.6 0.3 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KLO16113.1 - 5.2e-29 100.1 0.1 9.9e-29 99.2 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KLO16113.1 - 1.4e-23 82.0 13.3 0.0001 22.6 0.2 8.1 8 0 0 8 8 8 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KLO16113.1 - 0.0016 18.8 1.6 0.75 10.2 0.0 4.1 4 1 0 4 4 4 1 HEAT repeats Stn1_C PF12659.7 KLO16113.1 - 0.076 13.0 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Telomere capping C-terminal wHTH AMP-binding PF00501.28 KLO16114.1 - 1.5e-89 300.5 0.0 2.6e-89 299.7 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KLO16114.1 - 3e-08 34.5 0.0 9.5e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.22 KLO16115.1 - 5.9e-55 186.8 0.0 7.5e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.22 KLO16116.1 - 1.5e-05 24.7 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KLO16116.1 - 2.1e-05 24.3 7.5 3.2e-05 23.7 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO16116.1 - 0.0011 18.8 8.4 0.0022 17.8 8.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KLO16116.1 - 0.0026 17.7 8.7 0.0051 16.7 8.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KLO16116.1 - 0.0043 16.9 9.2 0.0079 16.1 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO16116.1 - 0.016 15.1 8.7 0.034 14.0 8.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO16116.1 - 0.018 15.0 7.7 0.042 13.9 7.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Metal_CEHH PF14455.6 KLO16116.1 - 0.032 13.8 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Predicted metal binding domain DbpA PF03880.15 KLO16116.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain zf-RING_2 PF13639.6 KLO16116.1 - 0.049 14.0 9.0 0.11 12.8 9.0 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KLO16116.1 - 0.26 11.1 1.5 0.5 10.2 1.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain G-alpha PF00503.20 KLO16117.1 - 2.1e-99 333.0 0.0 1.4e-98 330.3 0.0 1.9 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO16117.1 - 3.2e-09 36.5 0.0 6e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_24 PF13479.6 KLO16117.1 - 0.016 14.9 0.0 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KLO16117.1 - 0.089 13.1 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain CBS PF00571.28 KLO16118.1 - 1.6e-06 28.4 0.1 0.059 13.8 0.0 2.2 2 0 0 2 2 2 2 CBS domain VPS11_C PF12451.8 KLO16118.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal Mlh1_C PF16413.5 KLO16119.1 - 1.9e-90 302.9 0.1 3.2e-90 302.2 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus HATPase_c_3 PF13589.6 KLO16119.1 - 2e-13 50.3 0.0 5.3e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KLO16119.1 - 8.7e-11 41.5 0.5 3.1e-08 33.3 0.7 2.5 1 1 1 2 2 2 2 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KLO16119.1 - 4.1e-08 33.7 0.0 1.8e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MOR2-PAG1_N PF14222.6 KLO16120.1 - 2.6e-160 535.0 0.0 5.4e-160 534.0 0.0 1.6 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KLO16120.1 - 6.6e-85 285.0 1.1 1.4e-84 283.9 1.1 1.6 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KLO16120.1 - 1.4e-15 56.1 0.2 8e-09 33.7 0.0 2.7 3 0 0 3 3 3 2 Cell morphogenesis central region PLAC8 PF04749.17 KLO16121.1 - 7.9e-11 42.8 4.3 9.8e-11 42.5 4.3 1.1 1 0 0 1 1 1 1 PLAC8 family RRM_1 PF00076.22 KLO16123.1 - 1.2e-15 57.1 0.0 3.8e-07 29.8 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IBR PF01485.21 KLO16123.1 - 4e-08 33.4 23.8 1.3e-05 25.3 8.1 4.8 5 0 0 5 5 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KLO16123.1 - 5e-06 26.3 5.9 5e-06 26.3 5.9 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO16123.1 - 4e-05 23.4 2.1 4e-05 23.4 2.1 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KLO16123.1 - 5.5e-05 23.2 6.7 5.5e-05 23.2 6.7 5.4 5 1 1 6 6 4 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KLO16123.1 - 0.001 19.0 6.9 0.001 19.0 6.9 3.9 4 0 0 4 4 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KLO16123.1 - 0.0021 17.9 4.6 0.0021 17.9 4.6 4.9 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO16123.1 - 0.0026 18.0 5.0 0.0026 18.0 5.0 5.4 4 1 2 6 6 3 1 Ring finger domain Nup35_RRM_2 PF14605.6 KLO16123.1 - 0.086 12.9 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Torus PF16131.5 KLO16123.1 - 0.26 12.0 6.2 0.24 12.1 0.7 2.7 2 1 0 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 KLO16123.1 - 3.7 7.7 8.8 2.5 8.3 4.7 2.7 2 0 0 2 2 2 0 Zinc finger domain ATP19 PF11022.8 KLO16124.1 - 1.2e-18 67.2 2.9 2.2e-18 66.4 2.9 1.4 1 1 0 1 1 1 1 ATP synthase subunit K FAM76 PF16046.5 KLO16125.1 - 2.4 7.4 14.1 0.03 13.7 1.8 2.2 2 0 0 2 2 2 0 FAM76 protein AdoHcyase PF05221.17 KLO16126.1 - 4.2e-135 449.7 0.0 1.2e-73 247.9 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KLO16126.1 - 2.2e-85 284.6 0.7 3.3e-85 284.1 0.7 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KLO16126.1 - 1.4e-10 40.8 0.1 2.8e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KLO16126.1 - 0.00015 21.4 0.1 0.00026 20.6 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KLO16126.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.19 KLO16126.1 - 0.036 13.4 0.1 0.44 9.8 0.2 2.7 3 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ELFV_dehydrog PF00208.21 KLO16126.1 - 0.07 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GST_N PF02798.20 KLO16128.1 - 2e-08 34.4 0.0 3.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KLO16128.1 - 1.2e-05 25.6 0.0 2.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KLO16128.1 - 4e-05 23.7 0.0 5.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KLO16128.1 - 0.0025 17.8 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KLO16128.1 - 0.0092 16.3 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tht1 PF04163.12 KLO16129.1 - 6.5e-10 38.4 7.0 9.9e-10 37.8 7.0 1.2 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein Apolipoprotein PF01442.18 KLO16129.1 - 0.031 14.1 5.7 0.17 11.7 5.4 2.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain SF-assemblin PF06705.11 KLO16129.1 - 0.082 12.2 1.4 0.12 11.7 0.5 1.7 1 1 0 1 1 1 0 SF-assemblin/beta giardin Baculo_PEP_C PF04513.12 KLO16129.1 - 0.52 10.3 17.2 3.4 7.7 2.5 3.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 KLO16129.1 - 1.5 8.1 8.6 2.6 7.4 0.2 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Fzo_mitofusin PF04799.13 KLO16129.1 - 3.1 7.3 12.5 8.2 5.9 1.3 3.8 2 1 2 4 4 4 0 fzo-like conserved region Med2 PF11214.8 KLO16129.1 - 3.1 8.0 7.0 3.5 7.8 0.7 3.3 2 1 2 4 4 4 0 Mediator complex subunit 2 La PF05383.17 KLO16130.1 - 3.9e-21 74.8 0.1 5.9e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 La domain AbiEi_2 PF09952.9 KLO16130.1 - 0.11 12.7 0.2 0.14 12.4 0.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system U3_snoRNA_assoc PF08297.11 KLO16131.1 - 0.55 11.0 9.5 0.081 13.7 3.0 2.9 2 0 0 2 2 2 0 U3 snoRNA associated YihI PF04220.12 KLO16131.1 - 0.63 9.8 7.2 1.3 8.7 7.2 1.5 1 0 0 1 1 1 0 Der GTPase activator (YihI) Pkinase PF00069.25 KLO16133.1 - 1.5e-35 122.8 0.0 2e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16133.1 - 1.8e-13 50.4 0.0 2.3e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO16133.1 - 0.038 13.3 0.0 0.062 12.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KLO16133.1 - 0.045 12.5 0.0 0.082 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase MTBP_mid PF14919.6 KLO16133.1 - 0.07 12.3 0.1 0.14 11.4 0.0 1.4 2 0 0 2 2 2 0 MDM2-binding Pmp3 PF01679.17 KLO16134.1 - 4e-24 84.5 14.2 4.9e-24 84.3 14.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4191 PF13829.6 KLO16134.1 - 0.15 11.4 0.1 0.16 11.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) TPPK_C PF12555.8 KLO16134.1 - 0.16 12.0 0.9 0.25 11.4 0.9 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DCP1 PF06058.13 KLO16135.1 - 1.5e-28 99.0 0.0 2.3e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family PLAC8 PF04749.17 KLO16136.1 - 1.2e-19 71.1 14.7 2e-19 70.4 14.7 1.6 1 1 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 KLO16137.1 - 4e-20 72.7 19.4 4.9e-20 72.4 19.4 1.1 1 0 0 1 1 1 1 PLAC8 family adh_short PF00106.25 KLO16138.1 - 2e-23 82.9 0.0 2.5e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO16138.1 - 2.8e-16 59.8 0.0 3.5e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO16138.1 - 0.00032 20.7 0.0 0.00045 20.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KLO16138.1 - 0.016 14.8 0.2 0.04 13.5 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family Lactococcin PF04369.13 KLO16138.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Lactococcin-like family NAD_binding_10 PF13460.6 KLO16138.1 - 0.18 11.7 0.1 0.24 11.3 0.1 1.5 1 1 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 KLO16139.1 - 3.2e-15 56.1 0.0 8.1e-15 54.8 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO16139.1 - 2.7e-10 40.2 0.0 4e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PLAC8 PF04749.17 KLO16140.1 - 2.8e-17 63.5 23.4 3.5e-17 63.2 23.4 1.1 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 KLO16141.1 - 2.9e-17 63.5 17.8 4.3e-17 62.9 17.8 1.3 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 KLO16142.1 - 1.9e-19 70.5 13.9 2.3e-19 70.2 13.9 1.1 1 0 0 1 1 1 1 PLAC8 family GPI-anchored PF10342.9 KLO16143.1 - 5.1e-05 23.9 0.6 0.0001 23.0 0.6 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RAP1 PF07218.11 KLO16143.1 - 0.018 13.3 4.9 0.022 13.1 4.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CD99L2 PF12301.8 KLO16143.1 - 0.078 13.3 0.3 0.11 12.8 0.3 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 Herpes_capsid PF06112.11 KLO16143.1 - 7.1 6.7 13.2 10 6.2 13.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MFS_1 PF07690.16 KLO16145.1 - 4.2e-27 95.0 32.0 1.8e-25 89.6 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO16145.1 - 4.8e-09 35.6 0.5 4.8e-09 35.6 0.5 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KLO16145.1 - 4e-05 22.7 6.0 0.0002 20.4 1.2 2.3 2 0 0 2 2 2 2 MFS_1 like family TRI12 PF06609.13 KLO16145.1 - 0.00059 18.4 0.9 0.00059 18.4 0.9 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_1 PF00175.21 KLO16146.1 - 2.8e-26 92.3 0.0 4.3e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KLO16146.1 - 2e-14 53.7 0.0 3.8e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KLO16146.1 - 2.6e-06 27.6 0.3 0.00077 19.6 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KLO16146.1 - 0.2 11.9 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain eIF3g PF12353.8 KLO16147.1 - 3.7e-38 130.7 2.3 6.2e-38 130.0 2.3 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KLO16147.1 - 1.3e-15 56.9 0.0 2.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KLO16147.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FMN_red PF03358.15 KLO16148.1 - 1.3e-09 38.0 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KLO16148.1 - 3e-06 27.1 0.1 5.9e-06 26.1 0.0 1.5 1 1 1 2 2 2 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KLO16148.1 - 0.04 14.1 0.1 0.4 10.9 0.1 2.2 1 1 0 1 1 1 0 Flavodoxin Flavodoxin_5 PF12724.7 KLO16148.1 - 0.13 12.5 0.0 0.34 11.1 0.0 1.7 1 1 1 2 2 2 0 Flavodoxin domain Citrate_bind PF16114.5 KLO16149.1 - 5.2e-89 296.4 0.1 9.9e-89 295.5 0.1 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 KLO16149.1 - 5.2e-19 68.5 0.1 2.1e-15 56.6 0.0 3.7 2 1 1 3 3 3 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KLO16149.1 - 1.5e-15 57.4 0.1 2.8e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KLO16149.1 - 1.8e-13 50.9 0.0 5.2e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 KLO16149.1 - 2e-07 30.8 0.0 4.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KLO16149.1 - 7.1e-06 25.9 0.0 3.5e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain DUF2264 PF10022.9 KLO16150.1 - 7e-139 462.8 0.6 8.6e-139 462.5 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) DJ-1_PfpI PF01965.24 KLO16151.1 - 2.3e-40 138.1 0.1 2.6e-40 137.9 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 KLO16151.1 - 0.011 15.3 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain YAcAr PF10686.9 KLO16151.1 - 0.054 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family zf-MYND PF01753.18 KLO16152.1 - 2.8e-08 33.7 17.0 5.7e-08 32.7 17.0 1.6 1 0 0 1 1 1 1 MYND finger Adaptin_N PF01602.20 KLO16153.1 - 0.0031 16.2 0.1 0.0055 15.3 0.1 1.5 1 0 0 1 1 1 1 Adaptin N terminal region F-box-like PF12937.7 KLO16154.1 - 6.2e-08 32.4 0.0 1.8e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO16156.1 - 2.6e-06 27.2 0.0 1.4e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 F-box-like SAM_Ste50p PF09235.10 KLO16156.1 - 0.072 13.3 0.1 2 8.7 0.0 2.7 2 0 0 2 2 2 0 Ste50p, sterile alpha motif F-box-like PF12937.7 KLO16157.1 - 2.6e-06 27.2 0.0 6.4e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO16158.1 - 1.1e-08 34.9 0.3 2.8e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO16159.1 - 2.2e-08 33.8 0.0 5.8e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF3267 PF11667.8 KLO16161.1 - 0.02 15.2 1.0 0.02 15.2 1.0 2.5 2 1 1 3 3 3 0 Putative zincin peptidase F-box-like PF12937.7 KLO16163.1 - 1.7e-06 27.8 0.0 3.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF3420 PF11900.8 KLO16163.1 - 0.089 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) MrpF_PhaF PF04066.13 KLO16164.1 - 3.4 8.1 9.9 10 6.6 1.6 2.8 2 0 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) Herpes_UL20 PF04544.12 KLO16166.1 - 0.0018 18.7 1.1 0.0018 18.7 1.1 1.9 1 1 0 2 2 2 1 Herpesvirus egress protein UL20 Thoc2 PF11732.8 KLO16166.1 - 0.016 15.2 0.2 6.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Transcription- and export-related complex subunit TMEM234 PF10639.9 KLO16171.1 - 0.1 12.6 1.3 0.14 12.2 1.3 1.2 1 0 0 1 1 1 0 Putative transmembrane family 234 Sacchrp_dh_NADP PF03435.18 KLO16174.1 - 3.6e-18 66.1 0.1 5.5e-18 65.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KLO16174.1 - 1.5e-07 31.5 0.1 2.5e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KLO16174.1 - 8.4e-05 22.1 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KLO16174.1 - 0.002 18.3 0.0 0.0052 16.9 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KLO16174.1 - 0.0025 18.3 0.0 0.0056 17.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KLO16174.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KLO16174.1 - 0.019 14.5 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.20 KLO16174.1 - 0.069 13.2 0.3 0.15 12.1 0.3 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.10 KLO16174.1 - 0.079 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 KLO16174.1 - 0.11 11.8 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase F-box-like PF12937.7 KLO16175.1 - 1.8e-05 24.6 0.1 3.9e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO16175.1 - 0.1 12.5 0.2 0.46 10.4 0.2 2.2 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO16176.1 - 7.6e-07 28.9 0.7 2.1e-06 27.5 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO16177.1 - 1e-06 28.5 0.1 2.2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO16180.1 - 4.4e-06 26.5 0.1 8.5e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO16181.1 - 3.4e-06 26.9 0.3 8.7e-06 25.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO16181.1 - 0.092 12.7 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 F-box domain DUF150 PF02576.17 KLO16181.1 - 0.18 12.2 0.0 53 4.3 0.0 3.7 4 0 0 4 4 4 0 RimP N-terminal domain DUF5413 PF17434.2 KLO16183.1 - 0.0045 17.3 0.5 0.007 16.7 0.5 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5413) Mx_ML PF17536.2 KLO16184.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 Matrix and Matrix long proteins N-terminal DUF5325 PF17259.2 KLO16186.1 - 0.019 14.8 0.1 0.044 13.7 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5325) DUF5022 PF16425.5 KLO16186.1 - 0.061 12.8 0.2 0.069 12.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5022) RNA_pol_Rpb4 PF03874.16 KLO16188.1 - 1.1e-22 80.6 2.3 1.8e-22 79.9 2.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Carbpep_Y_N PF05388.11 KLO16188.1 - 0.05 14.1 0.5 5.4 7.6 0.1 2.2 1 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide DED PF01335.21 KLO16188.1 - 0.11 12.9 0.3 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 Death effector domain Ank_2 PF12796.7 KLO16189.1 - 2.2e-17 63.4 0.1 6.4e-12 45.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KLO16189.1 - 7.6e-11 42.0 0.7 0.00022 21.5 0.1 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KLO16189.1 - 5.6e-10 39.6 0.0 0.00063 20.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KLO16189.1 - 1.7e-08 34.0 0.1 0.028 14.9 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KLO16189.1 - 1.5e-07 31.5 1.4 0.01 16.2 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Monooxygenase_B PF04744.12 KLO16189.1 - 0.045 12.6 0.1 0.053 12.4 0.1 1.1 1 0 0 1 1 1 0 Monooxygenase subunit B protein Glyco_hydro_12 PF01670.16 KLO16190.1 - 0.066 13.2 0.5 0.12 12.4 0.5 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 Peptidase_M49 PF03571.15 KLO16192.1 - 1.1e-211 704.1 0.0 1.3e-211 703.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Erp_C PF06780.11 KLO16192.1 - 0.0055 16.7 0.3 0.038 14.0 0.1 2.3 2 0 0 2 2 2 1 Erp protein C-terminus Pkinase PF00069.25 KLO16193.1 - 1e-46 159.5 0.0 1.4e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16193.1 - 8.8e-44 149.7 0.0 1.2e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO16193.1 - 2e-07 30.6 0.0 3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Zn_clus PF00172.18 KLO16193.1 - 0.001 19.1 8.0 0.001 19.1 8.0 2.8 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lar_restr_allev PF14354.6 KLO16193.1 - 1.4 9.4 8.1 1.2 9.6 3.1 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_clus PF00172.18 KLO16194.1 - 6.5e-07 29.4 13.4 1e-06 28.7 13.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET_assoc PF11767.8 KLO16194.1 - 0.27 10.9 0.3 0.27 10.9 0.3 2.0 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Pkinase PF00069.25 KLO16195.1 - 1.3e-35 123.0 0.0 1.8e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16195.1 - 5.8e-34 117.5 0.0 8.1e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO16195.1 - 0.00039 20.4 0.0 0.00053 20.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO16195.1 - 0.00066 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrzO PF14142.6 KLO16195.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 YrzO-like protein Gti1_Pac2 PF09729.9 KLO16200.1 - 2.7e-29 102.5 1.6 1.4e-28 100.2 0.8 1.9 1 1 1 2 2 2 2 Gti1/Pac2 family Pkinase PF00069.25 KLO16202.1 - 4.3e-36 124.6 0.0 5e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16202.1 - 4.9e-34 117.8 0.0 5.7e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO16202.1 - 0.00042 19.7 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO16202.1 - 0.0023 17.9 0.0 0.004 17.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KLO16202.1 - 0.012 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 KLO16202.1 - 0.074 12.6 0.0 6 6.4 0.0 2.2 1 1 1 2 2 2 0 Choline/ethanolamine kinase Sld7_C PF18596.1 KLO16204.1 - 2.9e-06 27.3 0.1 4.9e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Sld7 C-terminal domain Herpes_UL14 PF03580.14 KLO16204.1 - 0.037 14.3 0.1 0.059 13.6 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL14-like protein EF-hand_14 PF17959.1 KLO16204.1 - 0.092 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain F-box-like PF12937.7 KLO16209.1 - 1.8e-05 24.5 0.2 7.7e-05 22.5 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO16209.1 - 0.064 13.2 0.2 21 5.2 0.2 2.8 2 0 0 2 2 2 0 F-box domain Zn_clus PF00172.18 KLO16210.1 - 2.1e-06 27.7 7.3 5.3e-06 26.5 7.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5547 PF17701.1 KLO16210.1 - 0.043 13.7 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5547) Cbl_N2 PF02761.14 KLO16213.1 - 0.14 12.9 0.0 0.21 12.3 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain Imm1 PF14430.6 KLO16216.1 - 0.13 13.0 0.4 8.5 7.1 0.2 2.2 1 1 1 2 2 2 0 Immunity protein Imm1 Zn_clus PF00172.18 KLO16219.1 - 2.3e-06 27.6 7.1 5e-06 26.5 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3624 PF12292.8 KLO16219.1 - 2.7 8.5 5.6 4.9 7.6 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) Zn_clus PF00172.18 KLO16222.1 - 1.6e-08 34.6 13.4 2.3e-08 34.0 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sperm_Ag_HE2 PF05324.13 KLO16223.1 - 0.032 14.7 0.0 0.071 13.6 0.0 1.6 1 1 0 1 1 1 0 Sperm antigen HE2 Zn_clus PF00172.18 KLO16226.1 - 0.0043 17.1 16.3 0.0043 17.1 16.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO16227.1 - 0.0023 18.0 16.6 0.0023 18.0 16.6 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO16228.1 - 8.1e-05 22.7 5.1 0.00012 22.1 5.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO16229.1 - 3.6e-05 23.8 5.7 4.7e-05 23.4 5.7 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KLO16229.1 - 1.1 9.8 6.6 7.3 7.2 6.6 2.0 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.18 KLO16230.1 - 5.7e-06 26.4 14.1 8.7e-06 25.8 14.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.23 KLO16231.1 - 2e-12 47.0 0.0 3e-07 30.3 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.12 KLO16231.1 - 3.8e-07 30.1 0.1 8.1e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KLO16231.1 - 0.0073 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding XET_C PF06955.12 KLO16235.1 - 4.8 7.1 6.1 0.78 9.6 1.0 2.2 2 0 0 2 2 2 0 Xyloglucan endo-transglycosylase (XET) C-terminus Glyco_hydro_31 PF01055.26 KLO16236.1 - 1.5e-143 479.2 1.5 1.9e-143 478.9 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KLO16236.1 - 5.5e-30 103.9 0.0 2.1e-29 102.1 0.0 1.9 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KLO16236.1 - 7.9e-07 29.3 0.0 2.8e-06 27.6 0.0 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like Ribosomal_L33 PF00471.20 KLO16237.1 - 3e-09 37.2 0.0 3.5e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.8 KLO16237.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal SpoIIAA-like PF11964.8 KLO16238.1 - 0.16 13.1 0.0 0.26 12.4 0.0 1.3 1 0 0 1 1 1 0 SpoIIAA-like HMG_box PF00505.19 KLO16240.1 - 8.3e-17 61.4 2.4 1.4e-16 60.6 2.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO16240.1 - 4.6e-13 49.6 1.0 4.6e-13 49.6 1.0 1.7 2 0 0 2 2 2 1 HMG-box domain adh_short_C2 PF13561.6 KLO16241.1 - 4e-51 173.8 2.9 4.9e-51 173.5 2.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO16241.1 - 9.6e-38 129.6 0.2 1.2e-37 129.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO16241.1 - 1.6e-11 44.4 0.1 2.3e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KLO16241.1 - 0.00022 21.5 0.0 0.00042 20.6 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain PALP PF00291.25 KLO16241.1 - 0.0043 16.5 0.4 0.0057 16.1 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Adenine_deam_C PF13382.6 KLO16241.1 - 0.022 14.1 0.2 0.041 13.2 0.2 1.4 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain His_biosynth PF00977.21 KLO16241.1 - 0.031 13.7 0.1 0.059 12.8 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF2527 PF10736.9 KLO16243.1 - 0.04 13.7 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Mem_trans PF03547.18 KLO16244.1 - 2.2e-22 79.0 1.2 2.8e-22 78.7 1.2 1.1 1 0 0 1 1 1 1 Membrane transport protein Ribosomal_L33 PF00471.20 KLO16245.1 - 2.9e-09 37.2 0.0 3.5e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.8 KLO16245.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Collagen_bind_2 PF12904.7 KLO16246.1 - 0.11 12.5 0.1 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative collagen-binding domain of a collagenase Glyco_hydro_31 PF01055.26 KLO16247.1 - 2.4e-146 488.4 1.4 3.1e-146 488.0 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KLO16247.1 - 9.7e-30 103.1 0.0 2.2e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KLO16247.1 - 1e-07 32.1 0.1 2.9e-07 30.7 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like LRR_4 PF12799.7 KLO16250.1 - 0.029 14.8 0.9 18 5.9 0.2 3.8 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Pyridoxal_deC PF00282.19 KLO16255.1 - 8.6e-17 60.9 0.0 5.1e-09 35.3 0.0 3.1 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain PH PF00169.29 KLO16255.1 - 0.14 12.7 0.0 2.1 8.9 0.0 2.6 2 1 0 2 2 2 0 PH domain PTCB-BRCT PF12738.7 KLO16256.1 - 2.8e-31 107.3 1.7 4.9e-18 64.8 0.1 4.8 5 0 0 5 5 5 4 twin BRCT domain BRCT PF00533.26 KLO16256.1 - 3.6e-25 88.2 0.7 4.2e-09 36.7 0.0 6.0 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KLO16256.1 - 5.7e-24 84.3 0.1 5.8e-06 26.6 0.0 6.3 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KLO16256.1 - 7.1e-19 67.6 0.0 6.3e-15 54.9 0.0 3.9 4 0 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KLO16256.1 - 1.9e-12 47.3 1.3 0.00041 20.6 0.1 5.8 5 0 0 5 5 5 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KLO16256.1 - 0.00055 20.0 0.1 0.37 10.9 0.0 3.4 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain TFIIA PF03153.13 KLO16257.1 - 0.073 13.1 6.0 0.091 12.7 6.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lactamase_B_2 PF12706.7 KLO16259.1 - 2.2e-12 46.9 0.1 8.8e-11 41.7 0.1 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 KLO16259.1 - 0.00023 20.4 0.0 0.00059 19.1 0.0 1.6 2 0 0 2 2 2 1 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 KLO16259.1 - 0.00025 21.1 0.0 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ECH_1 PF00378.20 KLO16260.1 - 1.5e-41 142.4 0.2 1.9e-41 142.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KLO16260.1 - 2.4e-22 79.9 0.4 9.6e-21 74.6 0.1 1.8 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ERM PF00769.19 KLO16263.1 - 0.00044 20.2 10.7 0.00044 20.2 10.7 1.6 2 0 0 2 2 2 1 Ezrin/radixin/moesin family DUF812 PF05667.11 KLO16263.1 - 0.0014 17.6 0.6 0.0024 16.8 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TSKS PF15358.6 KLO16263.1 - 0.015 13.7 0.2 0.029 12.7 0.2 1.4 1 0 0 1 1 1 0 Testis-specific serine kinase substrate PilZ_2 PF16823.5 KLO16263.1 - 0.041 14.0 0.1 0.094 12.9 0.1 1.6 1 0 0 1 1 1 0 Atypical PilZ domain, cyclic di-GMP receptor DUF3450 PF11932.8 KLO16263.1 - 0.21 10.9 8.5 0.37 10.1 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4337 PF14235.6 KLO16263.1 - 0.3 11.2 8.6 0.72 9.9 8.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) GrpE PF01025.19 KLO16263.1 - 7.8 6.1 8.9 12 5.5 8.2 1.6 1 1 0 1 1 1 0 GrpE DEAD PF00270.29 KLO16265.1 - 1.1e-21 77.4 0.0 1.3e-19 70.7 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO16265.1 - 9.4e-13 48.5 0.0 3.5e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO16265.1 - 3.6e-05 23.8 0.0 0.00018 21.6 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit BORG_CEP PF14957.6 KLO16265.1 - 0.019 16.1 3.3 4 8.6 0.0 2.7 2 0 0 2 2 2 0 Cdc42 effector LSM PF01423.22 KLO16266.1 - 3.5e-18 65.1 0.3 3.9e-18 64.9 0.3 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KLO16266.1 - 4.6e-05 23.5 0.1 5.5e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SRA1 PF07304.11 KLO16266.1 - 0.092 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Fungal_lectin_2 PF18647.1 KLO16269.1 - 0.052 14.0 0.2 0.28 11.7 0.1 2.0 2 0 0 2 2 2 0 Alpha-galactosyl-binding fungal lectin GMC_oxred_N PF00732.19 KLO16270.1 - 8.5e-51 173.1 0.0 1.2e-50 172.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO16270.1 - 3.8e-30 105.3 0.0 7.7e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KLO16270.1 - 8.6e-07 28.4 1.2 0.00033 19.9 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KLO16270.1 - 3.7e-05 22.9 0.1 5.7e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KLO16270.1 - 4.9e-05 23.1 1.0 0.001 18.8 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO16270.1 - 5e-05 22.7 0.1 0.00087 18.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO16270.1 - 5.1e-05 23.4 0.8 0.00017 21.7 0.8 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KLO16270.1 - 0.0059 15.9 0.6 0.089 12.0 0.5 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO16270.1 - 0.022 14.0 0.3 0.037 13.3 0.3 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KLO16270.1 - 0.059 12.1 0.8 0.11 11.2 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KLO16270.1 - 0.082 12.9 0.2 0.23 11.4 0.2 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 KLO16270.1 - 0.096 11.7 0.1 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A GMC_oxred_N PF00732.19 KLO16271.1 - 5.3e-55 186.9 0.1 7.3e-55 186.4 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO16271.1 - 6.4e-30 104.6 0.1 1.1e-29 103.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KLO16271.1 - 2.7e-07 30.0 0.4 0.00071 18.8 0.4 2.5 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 KLO16271.1 - 1.1e-05 25.2 0.4 0.00014 21.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO16271.1 - 5.2e-05 23.4 0.6 0.00016 21.8 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO16271.1 - 0.00015 21.1 0.1 0.00064 19.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KLO16271.1 - 0.00022 20.4 0.1 0.00036 19.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KLO16271.1 - 0.0049 16.2 0.0 0.044 13.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO16271.1 - 0.024 13.9 0.3 0.043 13.1 0.3 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KLO16271.1 - 0.027 13.6 0.1 0.045 12.8 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KLO16271.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KLO16271.1 - 0.17 10.5 1.1 0.2 10.4 0.2 1.4 2 0 0 2 2 2 0 HI0933-like protein Dynamin_N PF00350.23 KLO16273.1 - 6.5e-12 45.8 0.0 3.3e-11 43.5 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KLO16273.1 - 1.4e-05 25.2 0.0 0.006 16.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Spore_IV_A PF09547.10 KLO16273.1 - 0.053 12.5 1.2 0.12 11.3 0.0 2.0 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) FeoB_N PF02421.18 KLO16273.1 - 0.071 12.6 0.0 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ACP_PD PF04336.12 KLO16273.1 - 0.12 12.8 3.9 17 5.9 0.1 4.0 3 1 0 3 3 3 0 Acyl carrier protein phosphodiesterase AAA_18 PF13238.6 KLO16273.1 - 0.3 11.6 2.9 30 5.2 0.0 3.8 4 0 0 4 4 4 0 AAA domain Dynamin_N PF00350.23 KLO16274.1 - 1.1e-10 41.9 0.0 9.6e-10 38.8 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KLO16274.1 - 0.0013 18.8 0.0 1.6 8.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF3490 PF11995.8 KLO16274.1 - 0.023 14.5 1.0 0.067 13.0 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) DUF445 PF04286.12 KLO16274.1 - 0.026 14.3 3.0 0.12 12.1 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF4259 PF14078.6 KLO16274.1 - 1.3 9.7 4.6 66 4.2 0.7 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4259) Dynamin_N PF00350.23 KLO16275.1 - 0.0024 17.9 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_N PF00350.23 KLO16276.1 - 7.3e-07 29.4 0.0 2.6e-05 24.3 0.0 3.1 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KLO16276.1 - 0.0032 17.5 0.0 1.2 9.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase KNTase_C PF07827.11 KLO16276.1 - 0.012 15.5 0.9 0.22 11.4 0.1 2.7 2 0 0 2 2 2 0 KNTase C-terminal domain BAR_3 PF16746.5 KLO16276.1 - 1.4 8.6 9.9 0.14 11.8 0.5 3.1 3 0 0 3 3 3 0 BAR domain of APPL family GMC_oxred_N PF00732.19 KLO16277.1 - 7.4e-51 173.3 0.0 1e-50 172.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO16277.1 - 1e-28 100.7 0.0 1.8e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KLO16277.1 - 1.9e-05 23.9 0.1 0.0099 15.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KLO16277.1 - 9.1e-05 22.2 0.2 0.00051 19.7 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO16277.1 - 0.00022 21.4 0.0 0.00064 19.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KLO16277.1 - 0.001 18.2 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KLO16277.1 - 0.0059 15.9 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KLO16277.1 - 0.036 13.3 0.1 2.2 7.5 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KLO16277.1 - 0.048 12.9 0.0 0.43 9.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KLO16277.1 - 0.095 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain dCMP_cyt_deam_1 PF00383.23 KLO16279.1 - 2.2e-17 62.8 0.1 3.5e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KLO16279.1 - 4.2e-17 62.2 0.1 5.8e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KLO16279.1 - 6.6e-07 29.4 0.2 1.6e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KLO16279.1 - 2.4e-05 24.5 0.0 0.00056 20.0 0.0 2.0 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 KLO16279.1 - 4.6e-05 23.5 0.0 0.00058 20.0 0.0 2.0 2 0 0 2 2 2 1 APOBEC2 NAD2 PF18782.1 KLO16279.1 - 0.00017 21.7 0.0 0.00067 19.8 0.0 1.8 2 0 0 2 2 2 1 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 KLO16279.1 - 0.00018 21.5 0.0 0.00032 20.6 0.0 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC3 PF18771.1 KLO16279.1 - 0.0018 18.4 0.0 0.004 17.3 0.0 1.5 2 0 0 2 2 2 1 APOBEC3 APOBEC4_like PF18774.1 KLO16279.1 - 0.0048 16.8 0.1 0.034 14.1 0.0 1.9 2 0 0 2 2 2 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC4 PF18775.1 KLO16279.1 - 0.026 14.6 0.3 3.3 7.9 0.1 2.4 2 0 0 2 2 2 0 APOBEC4 Toxin-deaminase PF14424.6 KLO16279.1 - 0.045 13.8 0.2 1 9.5 0.1 2.2 2 1 0 2 2 2 0 The BURPS668_1122 family of deaminases APOBEC1 PF18769.1 KLO16279.1 - 0.048 13.9 0.0 2.2 8.6 0.0 2.2 2 0 0 2 2 2 0 APOBEC1 Bd3614-deam PF14439.6 KLO16279.1 - 0.089 12.9 0.9 0.26 11.4 0.9 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase NAP PF00956.18 KLO16280.1 - 1.9e-88 296.1 3.1 3.1e-88 295.5 3.1 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Striatin PF08232.12 KLO16280.1 - 0.069 13.7 1.0 0.19 12.3 0.1 1.9 2 0 0 2 2 2 0 Striatin family RNA_pol_3_Rpc31 PF11705.8 KLO16280.1 - 2.1 8.5 18.2 0.44 10.8 13.3 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 KLO16280.1 - 6.5 6.4 16.0 0.55 9.9 10.4 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KLO16280.1 - 7.1 4.6 8.4 12 3.9 8.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi He_PIG PF05345.12 KLO16281.1 - 3e-07 30.5 15.6 6.1e-05 23.1 1.8 4.3 4 0 0 4 4 4 2 Putative Ig domain Aldedh PF00171.22 KLO16282.1 - 1.4e-186 620.5 0.1 1.6e-186 620.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KLO16282.1 - 0.001 18.6 0.0 0.51 9.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 KLO16282.1 - 0.0032 16.6 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) zf-C6H2 PF15801.5 KLO16283.1 - 0.047 14.0 0.9 0.14 12.5 0.9 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-H2C2_2 PF13465.6 KLO16283.1 - 0.073 13.5 1.0 18 5.9 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Rep_fac_C PF08542.11 KLO16283.1 - 0.18 12.2 0.0 7.2 7.1 0.0 2.7 3 0 0 3 3 3 0 Replication factor C C-terminal domain Dynamin_N PF00350.23 KLO16285.1 - 3.1e-11 43.6 0.5 5.9e-10 39.5 0.0 3.0 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KLO16285.1 - 0.00027 21.0 0.0 0.32 11.1 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF3463 PF11946.8 KLO16285.1 - 0.039 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) KNTase_C PF07827.11 KLO16285.1 - 0.11 12.3 0.3 2.2 8.1 0.1 2.6 2 0 0 2 2 2 0 KNTase C-terminal domain Oxysterol_BP PF01237.18 KLO16288.1 - 5.1e-134 446.8 0.0 7.1e-134 446.3 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.6 KLO16288.1 - 1.6e-09 37.8 0.3 1.2e-07 31.8 0.0 3.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KLO16288.1 - 2.6e-09 37.5 0.0 4.6e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KLO16288.1 - 4.7e-09 36.6 0.2 2.2e-06 28.1 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 KLO16288.1 - 5.5e-09 36.5 0.0 1.4e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 KLO16288.1 - 7.6e-09 35.1 0.1 0.04 14.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KLO16288.1 - 2.1e-08 34.3 1.5 0.0036 17.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 KLO16288.1 - 0.0012 19.1 2.4 0.0056 16.9 0.5 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain iPGM_N PF06415.13 KLO16289.1 - 8.1e-79 264.1 0.0 1.2e-78 263.5 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KLO16289.1 - 1.3e-68 231.1 0.4 1.5e-68 230.9 0.4 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KLO16289.1 - 4.3e-09 36.2 0.0 8.5e-08 31.9 0.0 2.6 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KLO16289.1 - 2.6e-05 24.0 0.2 4.7e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 KLO16289.1 - 0.0026 16.8 1.7 0.0049 15.9 0.1 2.2 3 0 0 3 3 3 1 Alkaline phosphatase PglZ PF08665.12 KLO16289.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.6 2 0 0 2 2 2 0 PglZ domain AUDH_Cupin PF18637.1 KLO16290.1 - 1.1e-61 207.5 1.1 2e-61 206.7 1.1 1.5 1 0 0 1 1 1 1 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain PBP3 PF18056.1 KLO16290.1 - 2.8e-28 98.2 0.0 5e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Penicillin Binding Protein 3 Domain VCBS PF13517.6 KLO16290.1 - 2.8e-05 24.6 2.7 3.8 8.2 0.0 5.9 6 0 0 6 6 6 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KLO16290.1 - 0.0038 17.3 0.1 2.3 8.4 0.0 3.0 2 0 0 2 2 2 2 FG-GAP repeat RicinB_lectin_2 PF14200.6 KLO16290.1 - 0.0082 16.9 0.0 0.41 11.4 0.0 2.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like WW PF00397.26 KLO16291.1 - 0.0032 17.5 3.0 0.0073 16.4 3.0 1.6 1 0 0 1 1 1 1 WW domain PRA1 PF03208.19 KLO16291.1 - 0.75 9.4 4.5 0.23 11.1 0.4 2.1 2 0 0 2 2 2 0 PRA1 family protein Caa3_CtaG PF09678.10 KLO16291.1 - 5.3 6.4 11.3 0.03 13.8 0.8 2.3 3 0 0 3 3 3 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) FIVAR PF07554.13 KLO16293.1 - 0.0059 17.4 1.3 0.078 13.8 0.8 2.8 2 0 0 2 2 2 1 FIVAR domain Dynamin_N PF00350.23 KLO16294.1 - 8e-12 45.5 0.0 1.3e-09 38.4 0.0 3.7 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KLO16294.1 - 5.6e-05 23.2 0.0 0.014 15.5 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase MoeA_N PF03453.17 KLO16304.1 - 1.5e-36 125.5 0.1 2.3e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KLO16304.1 - 1.1e-26 93.3 0.0 1.8e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 KLO16304.1 - 9.7e-14 51.3 0.0 2.2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) PI3_PI4_kinase PF00454.27 KLO16306.1 - 8e-54 183.1 0.0 1.5e-53 182.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KLO16306.1 - 1.9e-30 106.3 2.1 4.7e-30 105.0 2.1 1.7 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KLO16306.1 - 4.9e-25 87.4 0.0 1.7e-24 85.6 0.0 2.1 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 KLO16306.1 - 1.5e-12 47.1 0.5 5e-11 42.2 0.0 2.6 2 0 0 2 2 2 1 FATC domain Herpes_UL51 PF04540.13 KLO16306.1 - 0.014 15.2 0.6 0.055 13.2 0.0 2.3 3 0 0 3 3 3 0 Herpesvirus UL51 protein YEATS PF03366.16 KLO16307.1 - 2.2e-38 130.1 0.2 3.5e-38 129.5 0.2 1.3 1 0 0 1 1 1 1 YEATS family COX7a PF02238.15 KLO16308.1 - 2.4e-17 63.1 0.6 1.3e-16 60.7 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c oxidase subunit VII Coiled-coil_56 PF09813.9 KLO16308.1 - 9.2e-07 28.9 1.1 1.2e-06 28.5 0.0 1.8 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 56 Ribonucleas_3_3 PF14622.6 KLO16309.1 - 5.9e-16 58.8 0.0 8.5e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KLO16309.1 - 9.3e-16 58.4 0.1 2.1e-15 57.2 0.1 1.6 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KLO16309.1 - 8.6e-10 39.2 0.1 3.7e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Double-stranded RNA binding motif PAPS_reduct PF01507.19 KLO16310.1 - 1.3e-38 132.8 0.0 1.7e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Atg29_N PF18388.1 KLO16311.1 - 1.2e-10 41.0 0.5 2.3e-10 40.1 0.5 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain E_Pc_C PF06752.12 KLO16311.1 - 0.036 14.2 1.1 0.036 14.2 1.1 2.6 2 1 0 2 2 2 0 Enhancer of Polycomb C-terminus LAMTOR PF15454.6 KLO16311.1 - 0.065 13.8 2.3 0.32 11.6 2.3 2.2 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF4746 PF15928.5 KLO16311.1 - 0.29 10.5 3.0 0.88 8.9 2.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Asp_protease PF09668.10 KLO16312.1 - 6e-20 71.3 0.2 1e-19 70.5 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 KLO16312.1 - 5.1e-08 32.6 0.0 9.7e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.6 KLO16312.1 - 0.00018 22.0 0.0 0.00048 20.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Rad60-SLD PF11976.8 KLO16312.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Asp_protease_2 PF13650.6 KLO16312.1 - 0.012 16.3 0.0 0.043 14.5 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease UTRA PF07702.13 KLO16312.1 - 0.036 13.9 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 UTRA domain Ubiquitin_2 PF14560.6 KLO16312.1 - 0.18 12.3 0.1 0.64 10.5 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain TFIID-18kDa PF02269.16 KLO16313.1 - 2.5e-32 110.7 0.1 5.2e-32 109.7 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIIE-A_C PF11521.8 KLO16313.1 - 0.0023 18.2 2.1 0.0045 17.2 2.1 1.5 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha Sec5 PF15469.6 KLO16313.1 - 0.093 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 BTB PF00651.31 KLO16316.1 - 2.5e-05 24.5 0.2 5.2e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain UPF0029 PF01205.19 KLO16317.1 - 3.9e-30 104.3 0.0 8.4e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KLO16317.1 - 1e-05 25.8 0.0 2.5e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 RWD domain p450 PF00067.22 KLO16318.1 - 6.3e-16 58.2 0.0 8.1e-16 57.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO16319.1 - 1.8e-46 158.9 0.1 1.2e-45 156.1 0.1 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO16320.1 - 7.6e-67 226.0 0.2 7.5e-66 222.8 0.2 2.1 1 1 0 1 1 1 1 Cytochrome P450 Dynamin_N PF00350.23 KLO16323.1 - 3e-16 59.9 0.0 3e-16 59.9 0.0 3.7 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KLO16323.1 - 6.7e-05 23.0 0.2 0.0017 18.4 0.2 2.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO16323.1 - 0.014 15.3 0.1 0.014 15.3 0.1 3.2 4 0 0 4 4 4 0 RsgA GTPase T2SSE PF00437.20 KLO16323.1 - 0.071 12.2 0.1 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 KLO16323.1 - 0.14 12.4 0.0 0.58 10.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KLO16323.1 - 0.19 11.1 1.0 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KLO16323.1 - 0.32 11.5 0.1 0.32 11.5 0.1 3.0 3 0 0 3 3 3 0 ABC transporter AIG1 PF04548.16 KLO16323.1 - 0.39 10.0 4.3 0.19 11.0 0.1 2.6 3 0 0 3 3 3 0 AIG1 family RecG_N PF17190.4 KLO16323.1 - 9.5 7.0 9.4 38 5.1 0.2 3.3 3 0 0 3 3 3 0 RecG N-terminal helical domain Thiolase_N PF00108.23 KLO16325.1 - 6.9e-85 284.5 2.9 9.5e-85 284.1 2.9 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KLO16325.1 - 4.5e-42 142.6 1.0 1.2e-41 141.3 0.8 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KLO16325.1 - 0.00081 19.0 2.9 0.044 13.4 2.2 2.6 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KLO16325.1 - 0.0066 16.6 0.1 0.027 14.6 0.1 2.1 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DRTGG PF07085.12 KLO16325.1 - 0.094 12.5 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 DRTGG domain TraW_N PF12477.8 KLO16325.1 - 0.1 12.6 0.2 0.4 10.7 0.2 2.0 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal ACP_syn_III PF08545.10 KLO16325.1 - 0.22 11.4 2.5 6 6.8 0.5 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MFS_1 PF07690.16 KLO16326.1 - 2.6e-36 125.3 22.6 3.4e-36 124.9 22.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OSTbeta PF15048.6 KLO16326.1 - 0.042 14.0 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein PKcGMP_CC PF16808.5 KLO16326.1 - 0.7 9.8 2.8 4.7 7.2 0.4 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MFS_1 PF07690.16 KLO16327.1 - 2.8e-33 115.3 29.9 3.8e-33 114.9 29.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1180 PF06679.12 KLO16327.1 - 0.0019 18.6 0.0 0.0035 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF3139 PF11337.8 KLO16327.1 - 0.0096 16.5 0.0 0.23 12.1 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3139) AAA_8 PF12780.7 KLO16327.1 - 0.029 13.7 0.4 0.11 11.7 0.1 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 DC_STAMP PF07782.13 KLO16327.1 - 0.048 13.5 0.3 0.11 12.4 0.3 1.6 1 0 0 1 1 1 0 DC-STAMP-like protein Sugarporin_N PF11471.8 KLO16327.1 - 0.058 13.4 0.1 0.21 11.5 0.1 2.0 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Autophagy_act_C PF03987.15 KLO16328.1 - 6.1e-16 58.8 0.1 1.1e-15 58.0 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ribosomal_S3Ae PF01015.18 KLO16329.1 - 3.1e-93 311.0 2.5 3.8e-93 310.7 2.5 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KLO16329.1 - 0.075 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Pribosyltran PF00156.27 KLO16330.1 - 9.6e-14 51.2 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KLO16330.1 - 0.0081 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.20 KLO16331.1 - 4e-102 342.5 0.0 5.9e-102 341.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KLO16331.1 - 2.4e-05 24.3 0.0 5.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 PA domain Auto_anti-p27 PF06677.12 KLO16332.1 - 1.7e-27 95.3 2.8 2.7e-13 49.8 0.4 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Get5_C PF18514.1 KLO16332.1 - 0.03 14.0 2.4 1.4 8.7 0.1 3.1 3 0 0 3 3 3 0 Get5 C-terminal domain LOR PF04525.12 KLO16334.1 - 0.059 13.0 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 LURP-one-related Nop25 PF09805.9 KLO16335.1 - 0.0089 16.5 4.8 0.0089 16.5 4.8 3.0 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) DUF4611 PF15387.6 KLO16335.1 - 0.011 16.0 2.8 0.011 16.0 2.8 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) Rrp44_CSD1 PF17216.3 KLO16335.1 - 0.039 13.7 0.6 0.039 13.7 0.6 2.3 1 1 1 2 2 2 0 Rrp44-like cold shock domain Spt5_N PF11942.8 KLO16335.1 - 0.89 10.6 18.7 1.5 9.8 6.6 3.1 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ACPS PF01648.20 KLO16336.1 - 7.2e-17 61.6 0.0 8.4e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily GCV_T PF01571.21 KLO16337.1 - 5.4e-05 22.7 0.0 8.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Pet191_N PF10203.9 KLO16338.1 - 1.8e-27 95.4 4.4 1.9e-27 95.3 4.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KLO16338.1 - 0.1 12.7 5.6 1.3 9.1 0.5 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 KLO16338.1 - 0.21 11.3 3.8 1.1 9.0 0.2 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 KLO16338.1 - 1.1 9.3 6.2 0.84 9.7 0.3 2.3 2 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ATP_bind_1 PF03029.17 KLO16339.1 - 1.8e-76 257.2 0.0 2.1e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KLO16339.1 - 6.6e-05 23.4 0.0 0.00066 20.1 0.0 2.2 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 KLO16339.1 - 0.00056 20.2 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 KLO16339.1 - 0.00059 19.7 0.0 0.0068 16.2 0.0 2.2 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase PF06745.13 KLO16339.1 - 0.0023 17.3 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 KLO16339.1 - 0.0041 16.2 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 KLO16339.1 - 0.0048 16.6 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KLO16339.1 - 0.0067 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 KLO16339.1 - 0.007 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 KLO16339.1 - 0.0083 16.7 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KLO16339.1 - 0.014 15.7 0.0 0.054 13.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 KLO16339.1 - 0.018 15.1 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KLO16339.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF463 PF04317.12 KLO16339.1 - 0.023 13.6 0.0 0.052 12.5 0.0 1.5 2 0 0 2 2 2 0 YcjX-like family, DUF463 NTPase_1 PF03266.15 KLO16339.1 - 0.03 14.2 0.1 0.065 13.1 0.0 1.6 2 0 0 2 2 1 0 NTPase AAA_30 PF13604.6 KLO16339.1 - 0.04 13.6 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KLO16339.1 - 0.042 13.9 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 KLO16339.1 - 0.048 13.8 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KLO16339.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KLO16339.1 - 0.074 13.6 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 KLO16339.1 - 0.076 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 KLO16339.1 - 0.077 12.5 0.0 8.5 5.9 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 KLO16339.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KLO16339.1 - 0.11 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 KLO16339.1 - 0.12 12.5 0.0 0.36 10.9 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 KLO16339.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Zeta_toxin PF06414.12 KLO16339.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.7 KLO16339.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.29 KLO16339.1 - 0.18 12.2 0.0 0.45 10.9 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KLO16339.1 - 0.21 11.2 0.0 0.69 9.5 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mago-bind PF09282.10 KLO16341.1 - 1.7e-13 50.2 1.6 1.7e-13 50.2 1.6 1.8 2 0 0 2 2 2 1 Mago binding Red1 PF07964.11 KLO16341.1 - 2.4 6.3 13.4 3 6.0 13.4 1.0 1 0 0 1 1 1 0 Rec10 / Red1 DUF1640 PF07798.11 KLO16342.1 - 1.5e-38 132.6 6.0 2.1e-38 132.1 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF5327 PF17261.2 KLO16342.1 - 0.25 12.1 3.5 1.2 9.9 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5327) WD40 PF00400.32 KLO16343.1 - 1.5e-33 114.2 26.3 2.9e-06 27.9 0.1 10.8 10 0 0 10 10 10 8 WD domain, G-beta repeat DEAD PF00270.29 KLO16344.1 - 1.1e-15 57.8 0.0 2e-15 57.0 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO16344.1 - 6.2e-10 39.4 0.0 1.2e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_1 PF00076.22 KLO16345.1 - 2.8e-10 39.9 0.0 5.4e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_1_2 PF00155.21 KLO16346.1 - 7.6e-40 137.2 0.0 9e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KLO16346.1 - 1.6e-06 26.9 0.0 2.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KLO16346.1 - 4.7e-06 26.2 0.0 7.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KLO16346.1 - 0.0091 15.0 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KLO16346.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase WD40 PF00400.32 KLO16347.1 - 3.9e-11 43.3 7.6 0.031 15.1 0.2 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO16347.1 - 1.5e-08 34.8 0.0 0.00091 19.5 0.0 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO16347.1 - 3.5e-05 23.8 0.0 0.0073 16.2 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-CCHC PF00098.23 KLO16350.1 - 2.2e-09 37.0 28.5 0.00015 21.7 2.5 4.7 4 0 0 4 4 4 4 Zinc knuckle Med27 PF11571.8 KLO16350.1 - 0.063 13.7 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 27 RNA_POL_M_15KD PF02150.16 KLO16350.1 - 0.068 13.1 1.4 2.7 8.0 0.1 3.3 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Haspin_kinase PF12330.8 KLO16351.1 - 1.8e-61 208.1 0.0 2.8e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Sld5 PF05916.11 KLO16352.1 - 1.1e-22 80.5 0.6 1.6e-22 80.0 0.6 1.2 1 0 0 1 1 1 1 GINS complex protein Phytase-like PF13449.6 KLO16353.1 - 3.6e-39 135.4 0.1 4.8e-39 135.0 0.1 1.3 1 0 0 1 1 1 1 Esterase-like activity of phytase Phytase-like PF13449.6 KLO16354.1 - 1.9e-37 129.7 0.0 2.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase Big_9 PF17963.1 KLO16354.1 - 0.34 11.7 2.8 0.66 10.8 0.4 2.6 2 0 0 2 2 2 0 Bacterial Ig domain P21-Arc PF04062.14 KLO16356.1 - 5.9e-71 238.1 0.0 6.6e-71 237.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NOB1_Zn_bind PF08772.11 KLO16357.1 - 2.4e-29 101.3 0.9 3.9e-29 100.6 0.9 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KLO16357.1 - 1.3e-26 92.9 0.0 2.7e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 PIN domain of ribonuclease Abdominal-A PF12407.8 KLO16357.1 - 0.042 13.4 3.8 0.13 11.9 3.8 1.9 1 0 0 1 1 1 0 Homeobox protein DZR PF12773.7 KLO16357.1 - 0.053 13.5 1.5 0.11 12.6 1.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 KLO16357.1 - 0.07 12.8 2.1 0.67 9.7 0.2 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C2HC5 PF06221.13 KLO16357.1 - 0.11 12.6 1.9 0.2 11.7 1.9 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Nudix_N_2 PF14803.6 KLO16357.1 - 0.21 11.6 0.1 0.21 11.6 0.1 2.1 2 0 0 2 2 2 0 Nudix N-terminal Iso_dh PF00180.20 KLO16358.1 - 1.8e-123 412.2 0.0 2e-123 411.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MRC1 PF09444.10 KLO16360.1 - 7.9e-24 84.8 26.7 7.9e-24 84.8 26.7 6.1 6 1 1 7 7 7 1 MRC1-like domain SesA PF17107.5 KLO16360.1 - 2.7 8.2 12.9 2.5 8.3 0.2 3.3 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases adh_short PF00106.25 KLO16361.1 - 1.9e-44 151.5 0.8 2.9e-44 150.9 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO16361.1 - 1.7e-29 103.1 0.1 2.4e-29 102.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO16361.1 - 1.8e-13 50.8 1.5 3.8e-12 46.5 1.4 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO16361.1 - 0.00023 20.7 1.4 0.0026 17.3 0.4 2.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Cyclin PF08613.11 KLO16362.1 - 6.2e-43 147.0 0.0 6.2e-43 147.0 0.0 2.5 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 KLO16362.1 - 0.039 13.7 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Alpha-amylase_C PF02806.18 KLO16363.1 - 8.9e-27 93.4 0.1 3e-26 91.7 0.1 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KLO16363.1 - 2.1e-18 66.5 0.0 6.5e-18 64.9 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KLO16363.1 - 5.5e-11 42.6 0.1 1.9e-09 37.6 0.0 2.4 1 1 0 2 2 2 1 Alpha amylase, catalytic domain Ras PF00071.22 KLO16364.1 - 6e-06 25.9 0.0 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 2 Ras family Septin PF00735.18 KLO16364.1 - 0.0046 16.3 0.0 0.0079 15.5 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_16 PF13191.6 KLO16364.1 - 0.0084 16.5 0.0 0.015 15.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 KLO16364.1 - 0.013 15.2 0.2 0.033 13.9 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 KLO16364.1 - 0.016 15.4 0.1 0.031 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KLO16364.1 - 0.02 14.7 0.1 5.1 6.8 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KLO16364.1 - 0.024 14.9 0.6 0.089 13.1 0.2 1.9 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KLO16364.1 - 0.031 14.8 0.1 0.11 13.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter MobB PF03205.14 KLO16364.1 - 0.04 13.8 0.2 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.15 KLO16364.1 - 0.073 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain PduV-EutP PF10662.9 KLO16364.1 - 0.095 12.4 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Phage_T4_gp19 PF06841.12 KLO16364.1 - 0.13 12.2 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 T4-like virus tail tube protein gp19 PRK PF00485.18 KLO16364.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 KLO16364.1 - 0.13 12.1 0.0 2.2 8.1 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KLO16364.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KLO16364.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Arf PF00025.21 KLO16364.1 - 0.17 11.3 0.0 2.3 7.6 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family G-alpha PF00503.20 KLO16364.1 - 0.19 10.9 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.12 KLO16364.1 - 0.21 11.5 0.1 0.36 10.7 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.12 KLO16364.1 - 0.23 10.9 0.7 0.6 9.5 0.1 1.9 3 0 0 3 3 3 0 Poxvirus A32 protein RasGEF PF00617.19 KLO16365.1 - 5.2e-28 98.4 0.0 8.2e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KLO16365.1 - 4.3e-11 43.0 0.0 9.6e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Viral_helicase1 PF01443.18 KLO16365.1 - 0.0026 17.5 0.1 0.0054 16.5 0.1 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 KLO16365.1 - 0.0052 17.0 0.2 0.14 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO16365.1 - 0.045 14.1 0.1 0.33 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KLO16365.1 - 0.073 13.3 0.0 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Prenyltransf PF01255.19 KLO16365.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase RsgA_GTPase PF03193.16 KLO16365.1 - 0.16 11.9 0.0 1.4 8.8 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 KLO16365.1 - 0.18 12.4 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter SH3_1 PF00018.28 KLO16366.1 - 3.6e-22 77.7 0.0 9e-11 41.2 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KLO16366.1 - 7.8e-15 54.3 0.0 1.5e-10 40.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 KLO16366.1 - 6.1e-12 45.2 0.4 5.7e-07 29.3 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.24 KLO16366.1 - 3.9e-07 30.0 0.0 9.5e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 PX domain Not3 PF04065.15 KLO16367.1 - 9.1e-90 300.1 22.3 1.4e-89 299.5 22.3 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KLO16367.1 - 7.5e-44 149.0 5.8 3e-43 147.1 5.8 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 KLO16367.1 - 0.015 15.6 4.3 0.015 15.6 4.3 2.6 1 1 1 2 2 2 0 Syntaxin-like protein DUF1465 PF07323.12 KLO16367.1 - 1.4 8.7 7.5 0.32 10.8 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Ribosomal_L12 PF00542.19 KLO16368.1 - 5.1e-19 68.4 7.8 9e-18 64.4 4.6 2.4 2 1 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KLO16368.1 - 5.7e-13 48.3 4.4 7.2e-13 48.0 3.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain 7tm_3 PF00003.22 KLO16369.1 - 1.3e-05 25.0 14.5 1.9e-05 24.5 14.5 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR MARVEL PF01284.23 KLO16369.1 - 0.61 10.1 11.6 0.043 13.8 6.0 2.0 2 1 0 2 2 2 0 Membrane-associating domain TPR_1 PF00515.28 KLO16371.1 - 1.3e-08 34.3 10.8 0.0003 20.5 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KLO16371.1 - 2.9e-07 30.1 10.9 0.0011 18.9 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KLO16371.1 - 6.5e-05 22.8 0.0 0.0095 16.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KLO16371.1 - 0.00069 20.2 9.0 0.00076 20.1 0.3 3.6 2 2 2 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KLO16371.1 - 0.024 14.7 0.1 0.069 13.2 0.1 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KLO16371.1 - 0.027 15.1 0.1 2.3 9.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KLO16371.1 - 0.099 13.0 5.9 5.1 7.5 1.5 3.2 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KLO16371.1 - 0.15 12.6 4.1 0.2 12.2 0.3 2.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KLO16371.1 - 0.15 12.5 4.8 8.3 7.0 0.1 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat DAO PF01266.24 KLO16372.1 - 9.1e-36 124.2 0.0 1.2e-35 123.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NDUFA12 PF05071.16 KLO16373.1 - 4.6e-30 104.3 1.5 4.6e-30 104.3 1.5 1.4 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Ribosomal_L18_c PF14204.6 KLO16373.1 - 0.071 14.1 0.0 0.11 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region B12D PF06522.11 KLO16374.1 - 8.9e-15 54.2 0.3 1.2e-14 53.8 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Aldo_ket_red PF00248.21 KLO16375.1 - 9.6e-40 136.6 0.0 1.2e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_1 PF00515.28 KLO16376.1 - 1.6e-28 97.3 7.3 2.3e-07 30.3 0.0 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 KLO16376.1 - 1.8e-22 77.5 7.8 0.00027 20.8 0.0 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 KLO16376.1 - 5e-18 64.5 3.4 3.2e-05 23.5 0.0 5.1 3 2 2 5 5 5 4 TPR repeat STI1 PF17830.1 KLO16376.1 - 8.9e-17 60.8 0.0 7.3e-16 57.8 0.0 2.4 2 0 0 2 2 2 1 STI1 domain TPR_8 PF13181.6 KLO16376.1 - 1.2e-16 59.4 11.6 0.00063 19.8 0.4 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 KLO16376.1 - 1.2e-14 54.3 1.0 2.4e-09 37.4 0.1 4.3 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KLO16376.1 - 2.8e-14 53.5 0.1 2.9e-05 24.6 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KLO16376.1 - 1.3e-13 51.3 0.9 7.3e-06 26.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KLO16376.1 - 2.6e-11 42.7 0.5 0.06 13.4 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KLO16376.1 - 1.4e-10 40.8 1.4 0.001 19.3 0.1 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KLO16376.1 - 9.8e-09 35.3 0.1 0.76 10.8 0.0 5.1 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KLO16376.1 - 2.6e-07 30.8 1.3 1 10.1 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KLO16376.1 - 1.4e-06 28.4 0.1 0.0017 18.5 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KLO16376.1 - 1.6e-06 27.7 1.4 0.045 13.6 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO16376.1 - 0.00084 19.5 1.1 0.012 15.8 0.0 2.5 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 KLO16376.1 - 0.0011 19.4 0.5 0.074 13.5 0.1 2.3 2 0 0 2 2 2 1 Bacterial transcriptional activator domain Fungal_trans PF04082.18 KLO16377.1 - 5e-17 61.8 0.4 7.9e-17 61.2 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO16377.1 - 1.2e-05 25.3 8.6 2.6e-05 24.2 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup160 PF11715.8 KLO16378.1 - 3.2e-30 105.3 0.7 1.8e-29 102.8 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Stealth_CR4 PF17103.5 KLO16378.1 - 0.07 13.0 0.2 7 6.6 0.1 2.5 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 Cyt-b5 PF00173.28 KLO16380.1 - 4.5e-12 45.9 0.1 7.6e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RGS PF00615.19 KLO16381.1 - 3.4e-37 127.3 0.0 8.2e-37 126.1 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KLO16381.1 - 7.5e-13 48.3 0.0 1.2e-05 25.3 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Mrr_N PF14338.6 KLO16381.1 - 0.047 13.8 0.0 16 5.7 0.0 3.2 3 0 0 3 3 3 0 Mrr N-terminal domain Peptidase_M60 PF13402.6 KLO16381.1 - 0.1 12.1 0.0 0.72 9.3 0.0 2.0 2 0 0 2 2 2 0 Peptidase M60, enhancin and enhancin-like RNaseH_like PF04308.12 KLO16381.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease H-like Adap_comp_sub PF00928.21 KLO16382.1 - 1.5e-59 201.5 0.0 2e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KLO16382.1 - 0.00021 21.3 0.0 0.00037 20.5 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sod_Fe_C PF02777.18 KLO16383.1 - 6.1e-16 58.4 0.0 6.1e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KLO16383.1 - 0.047 14.2 0.1 0.12 12.9 0.1 1.7 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DAD PF02109.16 KLO16384.1 - 7e-48 161.5 1.2 8.1e-48 161.3 1.2 1.0 1 0 0 1 1 1 1 DAD family DUF1748 PF08520.10 KLO16385.1 - 4.3e-27 93.8 0.0 4.8e-27 93.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PP-binding PF00550.25 KLO16385.1 - 0.081 13.3 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Phosphopantetheine attachment site Isochorismatase PF00857.20 KLO16386.1 - 7.7e-31 107.6 0.1 1.3e-30 106.9 0.1 1.3 1 1 0 1 1 1 1 Isochorismatase family ThylakoidFormat PF11264.8 KLO16387.1 - 0.055 13.2 1.2 0.078 12.7 0.0 1.8 2 0 0 2 2 2 0 Thylakoid formation protein WES_acyltransf PF03007.16 KLO16387.1 - 0.11 12.3 4.4 0.11 12.3 0.9 2.5 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain CENP-F_leu_zip PF10473.9 KLO16387.1 - 2.9 7.9 24.2 0.092 12.8 0.3 3.1 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3445 PF11927.8 KLO16388.1 - 9.2e-69 231.5 0.0 1.1e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) WEMBL PF05701.11 KLO16389.1 - 7.5e-06 24.9 46.9 1.5e-05 23.9 46.9 1.5 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Golgin_A5 PF09787.9 KLO16389.1 - 0.071 12.6 46.7 0.012 15.1 25.9 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 Mut7-C PF01927.16 KLO16389.1 - 6 7.0 12.5 0.17 12.0 5.0 2.3 2 1 0 2 2 2 0 Mut7-C RNAse domain HAUS-augmin3 PF14932.6 KLO16389.1 - 8.6 5.9 41.3 0.092 12.3 17.5 3.2 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 LOH1CR12 PF10158.9 KLO16390.1 - 2.5 8.1 8.9 1.2 9.1 0.3 3.7 2 1 2 4 4 4 0 Tumour suppressor protein Atg14 PF10186.9 KLO16391.1 - 0.0026 16.9 0.8 0.0029 16.7 0.8 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Sec2p PF06428.11 KLO16391.1 - 0.051 13.5 2.4 0.088 12.8 2.4 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p RGS PF00615.19 KLO16392.1 - 9.8e-14 51.6 0.3 2e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF1759 PF03564.15 KLO16392.1 - 0.0076 16.2 0.2 0.017 15.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DEP PF00610.21 KLO16392.1 - 0.053 13.6 0.1 0.78 9.8 0.0 2.6 2 1 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Sde2_N_Ubi PF13019.6 KLO16395.1 - 0.34 10.7 1.6 0.45 10.3 1.6 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Aft1_HRA PF11786.8 KLO16396.1 - 1.6e-15 57.2 16.3 1.6e-15 57.2 16.3 2.6 2 2 0 2 2 2 1 Aft1 HRA domain bZIP_1 PF00170.21 KLO16396.1 - 8.6e-10 38.6 9.8 2.2e-09 37.2 9.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KLO16396.1 - 2.2e-05 24.4 9.1 2.2e-05 24.4 9.1 2.6 2 0 0 2 2 2 1 Basic region leucine zipper Aft1_OSA PF11785.8 KLO16396.1 - 0.0011 19.4 1.2 0.0011 19.4 1.2 3.2 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain Aft1_HRR PF11787.8 KLO16396.1 - 0.0085 17.3 4.6 0.0085 17.3 4.6 4.0 4 2 0 4 4 4 1 Aft1 HRR domain MCC-bdg_PDZ PF10506.9 KLO16396.1 - 0.019 14.9 0.2 0.019 14.9 0.2 2.3 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome HCMV_UL139 PF12507.8 KLO16398.1 - 0.022 15.1 4.7 0.088 13.2 4.7 2.0 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein DEAD PF00270.29 KLO16401.1 - 3.7e-17 62.7 0.0 5.9e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO16401.1 - 2.1e-10 40.9 0.0 1.2e-09 38.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO16401.1 - 3e-09 37.1 0.2 1.7e-07 31.4 0.0 2.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 KLO16401.1 - 0.0027 17.9 0.0 0.34 11.0 0.0 2.4 1 1 1 2 2 2 1 Helicase C-terminal domain IFT43 PF15305.6 KLO16401.1 - 0.13 12.5 0.9 0.27 11.4 0.9 1.5 1 0 0 1 1 1 0 Intraflagellar transport protein 43 SH3_13 PF18335.1 KLO16402.1 - 0.059 13.2 0.3 7.4 6.5 0.1 2.8 3 0 0 3 3 3 0 ATP-dependent RecD-like DNA helicase SH3 domain RE_SacI PF09566.10 KLO16403.1 - 0.09 12.6 0.7 0.85 9.4 0.1 2.0 1 1 1 2 2 2 0 SacI restriction endonuclease DUF3339 PF11820.8 KLO16410.1 - 0.82 9.9 6.8 0.22 11.7 1.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3339) NAD_binding_8 PF13450.6 KLO16411.1 - 5.5e-10 39.3 0.0 1.3e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KLO16411.1 - 5.8e-08 31.6 0.2 0.012 14.0 0.1 3.3 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KLO16411.1 - 9.2e-05 22.5 0.2 0.0013 18.7 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KLO16411.1 - 0.0011 18.3 0.0 0.15 11.3 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO16411.1 - 0.0013 18.0 0.4 0.0048 16.2 0.0 2.0 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 KLO16411.1 - 0.083 12.5 0.1 2.2 7.8 0.1 2.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 KLO16411.1 - 0.14 11.3 0.1 26 3.8 0.0 3.0 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4148 PF13663.6 KLO16412.1 - 8.9 6.6 7.5 0.47 10.7 1.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) Sugar_tr PF00083.24 KLO16414.1 - 5.1e-36 124.5 17.3 2.8e-34 118.8 17.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO16414.1 - 1.1e-21 77.1 30.0 3.9e-14 52.3 9.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Corona_M PF01635.18 KLO16416.1 - 0.26 10.6 8.8 0.4 10.0 8.8 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein DDE_1 PF03184.19 KLO16423.1 - 4.7e-11 42.6 0.0 6.5e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease bPH_5 PF10882.8 KLO16428.1 - 0.049 13.7 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain Glyco_hydro_36 PF17167.4 KLO16429.1 - 0.013 14.2 0.0 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain RRM_1 PF00076.22 KLO16429.1 - 0.019 14.8 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_1 PF03184.19 KLO16433.1 - 5.4e-07 29.4 0.0 5.8e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KLO16434.1 - 6.9e-10 38.9 0.0 1.2e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease Pro-kuma_activ PF09286.11 KLO16441.1 - 1.1e-34 119.8 0.0 3.9e-34 118.0 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KLO16441.1 - 2.2e-08 33.7 1.7 3.8e-08 32.9 1.7 1.4 1 0 0 1 1 1 1 Subtilase family F-box-like PF12937.7 KLO16442.1 - 0.024 14.5 0.1 0.053 13.4 0.1 1.6 1 0 0 1 1 1 0 F-box-like DUF4428 PF14471.6 KLO16442.1 - 0.3 11.0 1.7 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) DUF1677 PF07911.13 KLO16443.1 - 0.046 14.1 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Vir_act_alpha_C PF10400.9 KLO16443.1 - 0.13 13.0 0.3 1.9 9.2 0.3 2.6 1 1 0 1 1 1 0 Virulence activator alpha C-term ICL PF00463.21 KLO16444.1 - 0.002 16.7 0.0 0.0039 15.7 0.0 1.5 1 1 1 2 2 2 1 Isocitrate lyase family APOBEC1 PF18769.1 KLO16444.1 - 0.071 13.4 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 APOBEC1 APOBEC4_like PF18774.1 KLO16444.1 - 0.071 13.0 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Senescence PF06911.12 KLO16446.1 - 4.8e-20 72.6 1.8 4.8e-20 72.6 1.8 1.7 2 0 0 2 2 2 1 Senescence-associated protein DUF3446 PF11928.8 KLO16446.1 - 0.98 9.8 12.9 0.35 11.2 1.7 3.2 3 0 0 3 3 3 0 Early growth response N-terminal domain CIMR PF00878.18 KLO16447.1 - 3.2e-09 37.0 0.1 1.4e-05 25.2 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 KLO16447.1 - 1.5e-05 25.0 0.6 0.00051 20.0 0.6 2.1 1 1 0 1 1 1 1 Autophagy-related protein 27 SRTM1 PF15872.5 KLO16447.1 - 0.12 12.5 0.2 0.12 12.5 0.2 1.9 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Dfp1_Him1_M PF08630.10 KLO16449.1 - 7.5e-27 94.0 0.9 2.1e-26 92.6 0.0 2.1 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 KLO16449.1 - 2.6e-19 69.0 0.5 6.8e-19 67.7 0.5 1.7 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 KLO16449.1 - 0.0029 17.9 0.0 0.0073 16.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KLO16449.1 - 0.01 15.8 0.0 0.092 12.7 0.0 2.3 2 0 0 2 2 2 0 twin BRCT domain DUF4620 PF15399.6 KLO16449.1 - 0.061 13.7 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) BRCT_2 PF16589.5 KLO16449.1 - 0.069 13.6 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain AP_endonuc_2 PF01261.24 KLO16454.1 - 3.3e-36 124.7 0.2 9.1e-36 123.3 0.0 1.8 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel G-alpha PF00503.20 KLO16457.1 - 9.6e-96 321.0 0.0 1.2e-95 320.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO16457.1 - 2.8e-09 36.7 0.1 1.1e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.6 KLO16457.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SVIP PF15811.5 KLO16457.1 - 1.4 9.5 7.8 0.18 12.3 2.7 2.0 2 0 0 2 2 2 0 Small VCP/p97-interacting protein KOW PF00467.29 KLO16458.1 - 1.6e-13 50.1 21.5 1e-05 25.3 0.3 5.5 5 0 0 5 5 5 4 KOW motif Spt5-NGN PF03439.13 KLO16458.1 - 9.5e-12 44.7 0.0 1.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF3912 PF13051.6 KLO16458.1 - 0.023 15.0 1.8 2.6 8.4 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3912) DUF3496 PF12001.8 KLO16458.1 - 0.56 10.6 2.1 1.5 9.2 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) HAS-barrel PF09378.10 KLO16458.1 - 2.4 8.4 6.8 3.6 7.8 0.0 3.3 4 0 0 4 4 4 0 HAS barrel domain Spt5_N PF11942.8 KLO16458.1 - 2.8 9.0 11.4 5.9 7.9 11.4 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal p450 PF00067.22 KLO16459.1 - 8.2e-49 166.6 0.0 1.4e-47 162.5 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 SR-25 PF10500.9 KLO16459.1 - 9.9 5.7 6.4 17 5.0 6.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Helicase_C PF00271.31 KLO16461.1 - 1.3e-05 25.5 0.0 3.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OrsD PF12013.8 KLO16461.1 - 2.9e-05 24.5 0.3 2.9e-05 24.5 0.3 3.0 3 0 0 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D DEAD PF00270.29 KLO16461.1 - 6.9e-05 22.7 0.1 0.00013 21.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.14 KLO16461.1 - 0.002 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer ZF-HD_dimer PF04770.12 KLO16461.1 - 0.036 14.4 0.2 0.092 13.1 0.2 1.6 1 0 0 1 1 1 0 ZF-HD protein dimerisation region ResIII PF04851.15 KLO16461.1 - 0.063 13.3 0.0 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MRG PF05712.13 KLO16461.1 - 0.19 11.0 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 MRG IBR PF01485.21 KLO16461.1 - 4.2 7.7 5.8 4.1 7.7 2.2 2.9 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain zf-MYND PF01753.18 KLO16462.1 - 9.8e-09 35.2 13.3 1.8e-08 34.4 13.3 1.4 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 KLO16462.1 - 2 6.2 6.2 2.8 5.7 6.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF2207 PF09972.9 KLO16463.1 - 0.00066 18.6 0.0 0.00087 18.2 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF2009 PF09418.10 KLO16463.1 - 0.027 13.6 0.4 0.039 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Cache_3-Cache_2 PF17201.4 KLO16463.1 - 0.062 12.6 0.2 0.14 11.4 0.1 1.6 2 0 0 2 2 2 0 Cache 3/Cache 2 fusion domain Endonuc-FokI_C PF09254.11 KLO16463.1 - 0.066 12.5 0.3 0.13 11.5 0.3 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Goodbye PF17109.5 KLO16463.1 - 0.072 13.5 3.3 0.87 10.0 0.9 3.3 1 1 3 4 4 4 0 fungal STAND N-terminal Goodbye domain DUF5063 PF16702.5 KLO16463.1 - 0.086 13.2 0.5 0.34 11.3 0.1 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5063) DUF3040 PF11239.8 KLO16463.1 - 0.099 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) FAA_hydro_N_2 PF18288.1 KLO16463.1 - 0.13 12.7 0.4 12 6.4 0.1 3.3 3 1 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 Fez1 PF06818.15 KLO16463.1 - 0.82 10.1 7.2 2.6 8.5 0.6 2.5 2 1 0 2 2 2 0 Fez1 FliD_N PF02465.18 KLO16463.1 - 1 10.1 11.3 1.3 9.7 2.2 4.1 3 2 1 4 4 4 0 Flagellar hook-associated protein 2 N-terminus Mating_N PF12731.7 KLO16463.1 - 1.6 8.8 7.3 0.44 10.7 1.2 3.1 2 1 2 4 4 4 0 Mating-type protein beta 1 DUF4201 PF13870.6 KLO16463.1 - 3.1 7.5 8.9 1.9 8.2 3.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Plk4_PB2 PF18409.1 KLO16463.1 - 4.3 8.1 6.1 1.5 9.6 0.3 2.8 3 2 0 3 3 2 0 Polo-like Kinase 4 Polo Box 2 zf-MYND PF01753.18 KLO16464.1 - 2.8e-08 33.7 13.6 5.3e-08 32.8 13.6 1.5 1 0 0 1 1 1 1 MYND finger DUF4781 PF16013.5 KLO16465.1 - 0.00026 19.9 0.0 0.00037 19.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4781) F_actin_bind PF08919.10 KLO16465.1 - 0.00044 20.3 0.3 0.0039 17.3 0.1 2.3 2 0 0 2 2 2 1 F-actin binding Syntaxin_2 PF14523.6 KLO16465.1 - 0.0062 16.9 0.8 0.056 13.8 0.0 2.7 3 1 0 3 3 3 1 Syntaxin-like protein DUF1664 PF07889.12 KLO16465.1 - 0.14 12.2 0.9 3.3 7.7 0.3 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF5446 PF17522.2 KLO16465.1 - 0.27 11.4 3.8 6.9 6.9 0.1 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5446) TMF_DNA_bd PF12329.8 KLO16465.1 - 1.1 9.3 6.1 5.2 7.2 1.5 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Mur_ligase_M PF08245.12 KLO16466.1 - 1.9e-07 31.3 0.0 5.3e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain Peroxin-3 PF04882.12 KLO16467.1 - 0.93 8.4 5.4 2.3 7.1 5.5 1.6 1 1 0 1 1 1 0 Peroxin-3 Phosphorylase PF00343.20 KLO16468.1 - 0 1016.1 0.0 0 1015.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase HC2 PF07382.11 KLO16469.1 - 0.35 10.9 2.6 0.96 9.5 0.2 2.6 3 1 1 4 4 4 0 Histone H1-like nucleoprotein HC2 DUF1708 PF08101.11 KLO16470.1 - 1.7e-15 57.2 0.0 1.1e-10 41.3 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF1708) FMN_dh PF01070.18 KLO16471.1 - 5.8e-105 351.1 0.0 7.9e-105 350.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KLO16471.1 - 7e-05 22.0 1.8 0.00071 18.7 0.2 2.7 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KLO16471.1 - 0.0019 17.5 0.2 0.031 13.6 0.0 2.5 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KLO16471.1 - 0.0031 16.7 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase PTR2 PF00854.21 KLO16472.1 - 4.2e-86 289.3 2.2 5.9e-86 288.8 2.2 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KLO16472.1 - 6.9e-11 41.7 30.7 1.2e-10 40.9 25.1 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily eIF-1a PF01176.19 KLO16472.1 - 0.063 13.1 0.0 7.3 6.5 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 Phage_holin_3_6 PF07332.11 KLO16472.1 - 4.7 7.3 11.4 3.3 7.8 0.1 3.4 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Amino_oxidase PF01593.24 KLO16473.1 - 2.9e-36 125.7 0.0 4.4e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KLO16473.1 - 8.3e-10 38.8 0.1 2.1e-09 37.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KLO16473.1 - 0.0021 16.8 0.4 0.01 14.6 0.4 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KLO16473.1 - 0.021 14.1 1.2 0.039 13.2 1.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO16473.1 - 0.026 13.8 0.7 4.8 6.4 0.2 2.3 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 KLO16473.1 - 0.13 11.5 0.4 0.19 10.9 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 KLO16473.1 - 0.17 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KLO16473.1 - 0.4 11.3 1.2 0.71 10.5 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LRR_4 PF12799.7 KLO16474.1 - 1.7e-05 25.1 2.7 4.7 7.8 0.7 4.8 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO16474.1 - 1.7e-05 24.6 0.0 4.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KLO16474.1 - 0.12 12.2 2.0 1.8 8.4 0.8 3.0 2 1 1 3 3 3 0 Leucine rich repeat F-box-like PF12937.7 KLO16475.1 - 4.8e-05 23.2 0.2 0.00014 21.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO16475.1 - 0.0003 21.1 10.8 0.8 10.2 0.0 5.5 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KLO16475.1 - 0.76 9.6 8.3 0.71 9.7 0.5 3.7 4 0 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.7 KLO16476.1 - 2.2e-06 27.4 0.0 7.8e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO16476.1 - 0.0019 18.6 1.3 0.099 13.1 0.0 3.8 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KLO16476.1 - 0.094 12.5 2.8 0.38 10.6 0.3 3.1 3 1 1 4 4 4 0 Leucine rich repeat F-box-like PF12937.7 KLO16477.1 - 7.7e-05 22.5 0.2 0.00026 20.8 0.1 1.9 2 0 0 2 2 2 1 F-box-like Amino_oxidase PF01593.24 KLO16478.1 - 5.5e-37 128.1 0.1 1.1e-36 127.1 0.1 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KLO16478.1 - 7.2e-11 42.2 0.0 2.6e-10 40.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KLO16478.1 - 0.0048 15.6 0.4 0.007 15.1 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KLO16478.1 - 0.03 13.5 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO16478.1 - 0.034 13.4 1.2 0.062 12.5 0.5 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO16478.1 - 0.049 14.2 0.1 0.17 12.5 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO16478.1 - 0.076 12.2 0.4 0.16 11.2 0.3 1.5 2 0 0 2 2 2 0 Thi4 family Amino_oxidase PF01593.24 KLO16479.1 - 5.5e-38 131.4 0.0 7.8e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KLO16479.1 - 0.0022 18.2 0.0 0.012 15.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Prenylcys_lyase PF07156.14 KLO16479.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase BTB PF00651.31 KLO16480.1 - 0.0067 16.6 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SRP9-21 PF05486.12 KLO16481.1 - 8.4e-10 38.9 1.3 6e-09 36.2 1.3 2.1 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) ArAE_2 PF10334.9 KLO16482.1 - 0.049 13.5 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 DUF1314 PF07013.11 KLO16486.1 - 0.03 14.2 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Aldedh PF00171.22 KLO16487.1 - 3e-06 26.0 0.6 3.1e-06 26.0 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FUSC_2 PF13515.6 KLO16488.1 - 0.00039 20.6 30.3 0.13 12.4 11.5 3.7 3 1 1 4 4 4 2 Fusaric acid resistance protein-like ALMT PF11744.8 KLO16488.1 - 0.0012 17.8 0.4 0.0018 17.2 0.4 1.3 1 0 0 1 1 1 1 Aluminium activated malate transporter ArAE_2_N PF10337.9 KLO16488.1 - 0.026 13.6 0.1 0.026 13.6 0.1 2.8 2 1 1 3 3 3 0 Putative ER transporter, 6TM, N-terminal FUSC-like PF12805.7 KLO16488.1 - 0.036 13.2 0.7 0.12 11.4 0.7 2.0 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Sdh_cyt PF01127.22 KLO16488.1 - 0.11 12.5 5.5 0.53 10.3 5.5 2.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ArAE_2 PF10334.9 KLO16488.1 - 0.14 12.0 0.3 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 Aromatic acid exporter family member 2 NKAIN PF05640.14 KLO16488.1 - 1 8.5 4.4 0.89 8.8 0.7 2.2 2 0 0 2 2 2 0 Na,K-Atpase Interacting protein UQ_con PF00179.26 KLO16490.1 - 1.9e-15 56.8 0.1 2.9e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.12 KLO16490.1 - 0.0079 15.1 0.1 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) TPR_18 PF13512.6 KLO16490.1 - 0.021 14.9 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RWD PF05773.22 KLO16490.1 - 0.095 13.0 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain GST_C_3 PF14497.6 KLO16491.1 - 2.6e-31 107.8 1.0 3.5e-30 104.1 0.9 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KLO16491.1 - 5.2e-09 36.2 0.2 1.2e-08 35.1 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KLO16491.1 - 0.00052 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LolA_like PF17131.4 KLO16491.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein Toxin_10 PF05431.11 KLO16492.1 - 0.0056 16.2 0.3 0.012 15.1 0.3 1.5 1 0 0 1 1 1 1 Insecticidal Crystal Toxin, P42 MreB_Mbl PF06723.13 KLO16492.1 - 0.21 10.4 0.0 0.43 9.3 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein ALO PF04030.14 KLO16493.1 - 1.1e-76 258.1 0.4 1.4e-76 257.7 0.4 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KLO16493.1 - 9.3e-28 96.7 0.0 1.5e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain UQ_con PF00179.26 KLO16494.1 - 1.5e-44 151.0 0.0 1.8e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mito_carr PF00153.27 KLO16495.1 - 6.5e-60 199.1 1.0 7.4e-21 73.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-MYND PF01753.18 KLO16497.1 - 1.7e-09 37.6 10.6 1.7e-09 37.6 10.6 2.2 3 0 0 3 3 3 1 MYND finger RAB3GAP2_N PF14655.6 KLO16497.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-C6H2 PF15801.5 KLO16497.1 - 6.4 7.2 11.5 5.7 7.3 7.6 2.9 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Dus PF01207.17 KLO16498.1 - 7.8e-54 182.9 0.0 1e-53 182.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHDPS PF00701.22 KLO16498.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Pilin_N PF07790.11 KLO16499.1 - 0.0062 17.4 4.2 0.013 16.4 4.2 1.5 1 0 0 1 1 1 1 Archaeal Type IV pilin, N-terminal DUF4366 PF14283.6 KLO16499.1 - 0.02 14.9 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Gemini_mov PF01708.16 KLO16499.1 - 0.11 12.3 0.5 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF4834 PF16118.5 KLO16499.1 - 1.6 9.8 3.4 4.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Acetyltransf_3 PF13302.7 KLO16500.1 - 5e-14 53.2 0.0 8.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO16500.1 - 1.1e-05 25.7 0.0 1.8e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KLO16500.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KLO16500.1 - 0.062 13.4 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO16500.1 - 0.083 12.9 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 KLO16501.1 - 3.2e-15 57.0 0.0 4.7e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO16501.1 - 3.4e-05 24.1 0.0 4.6e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KLO16501.1 - 0.13 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MspA PF09203.11 KLO16502.1 - 0.21 11.5 5.3 1.6 8.5 0.6 3.0 1 1 1 2 2 2 0 MspA zf-MYND PF01753.18 KLO16503.1 - 1e-11 44.7 13.0 2.8e-11 43.3 13.0 1.8 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 KLO16503.1 - 0.14 10.0 1.4 0.19 9.5 1.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.18 KLO16504.1 - 1e-09 38.3 13.4 2.2e-09 37.2 13.4 1.6 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 KLO16504.1 - 0.11 12.9 5.6 0.25 11.8 5.6 1.5 1 0 0 1 1 1 0 Rhodanase C-terminal PolC_DP2 PF03833.13 KLO16504.1 - 0.24 9.2 0.3 0.35 8.7 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Myb_DNA-binding PF00249.31 KLO16505.1 - 1.5e-16 60.3 0.1 3.2e-10 40.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KLO16505.1 - 5.7e-15 55.3 0.0 3.6e-07 30.3 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KLO16505.1 - 1.2e-05 25.4 0.1 0.0021 18.1 0.0 2.4 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 KLO16505.1 - 0.03 14.5 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 SNF2_N PF00176.23 KLO16506.1 - 3.9e-49 167.2 0.0 7.4e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 KLO16506.1 - 1.8e-07 30.9 9.9 3.4e-07 30.0 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO16506.1 - 2.3e-06 27.8 12.9 4.5e-06 26.9 12.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KLO16506.1 - 7.3e-06 25.8 12.0 1.5e-05 24.7 12.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO16506.1 - 1.1e-05 25.2 10.2 2.3e-05 24.2 10.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KLO16506.1 - 4.3e-05 23.3 11.8 8.2e-05 22.4 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 KLO16506.1 - 8.7e-05 22.8 0.6 0.0002 21.7 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KLO16506.1 - 0.00077 19.4 12.5 0.0015 18.5 12.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KLO16506.1 - 0.0032 17.7 8.0 0.0088 16.3 8.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KLO16506.1 - 0.0075 16.3 11.3 0.019 15.0 11.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KLO16506.1 - 0.014 15.0 9.7 0.026 14.1 9.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF4485 PF14846.6 KLO16506.1 - 0.056 13.5 0.1 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) zf-ANAPC11 PF12861.7 KLO16506.1 - 0.17 12.0 4.1 0.42 10.7 3.8 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KLO16506.1 - 0.24 11.3 2.0 0.54 10.2 2.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KLO16506.1 - 1.2 9.3 10.3 2.7 8.2 10.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KLO16506.1 - 6.1 6.7 6.7 21 5.0 6.2 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit MFS_1 PF07690.16 KLO16507.1 - 2.2e-21 76.2 46.0 5.6e-13 48.5 23.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO16507.1 - 5.2e-19 68.5 21.4 1.4e-17 63.8 21.4 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter Prefoldin PF02996.17 KLO16508.1 - 5e-28 97.4 2.1 2.7e-27 95.1 2.1 1.9 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KLO16508.1 - 0.00058 19.8 1.5 0.0057 16.6 0.2 2.2 2 0 0 2 2 2 1 Prefoldin subunit End3 PF12761.7 KLO16508.1 - 0.013 15.7 1.8 0.025 14.7 0.2 2.0 1 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Syntaxin-6_N PF09177.11 KLO16508.1 - 0.022 15.3 2.8 1.2 9.7 2.8 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 KLO16508.1 - 0.029 14.8 1.5 0.83 10.1 0.2 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) BCAS3 PF12490.8 KLO16508.1 - 0.069 12.7 0.2 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 CC2-LZ PF16516.5 KLO16508.1 - 7.2 7.0 8.7 14 6.1 5.0 2.8 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator RRM_1 PF00076.22 KLO16509.1 - 7.6e-56 185.8 0.1 1.1e-19 70.0 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KLO16509.1 - 2.5e-05 24.1 0.0 0.061 13.2 0.0 3.7 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KLO16509.1 - 0.0056 16.8 0.0 6.1 7.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif RRM_Rrp7 PF17799.1 KLO16509.1 - 0.011 15.5 0.8 6.7 6.5 0.0 4.7 4 2 2 6 6 6 0 Rrp7 RRM-like N-terminal domain RRM_2 PF04059.12 KLO16509.1 - 0.013 15.7 0.0 7.1 6.9 0.0 3.4 4 0 0 4 4 4 0 RNA recognition motif 2 zf-MYND PF01753.18 KLO16510.1 - 6.5e-10 38.9 12.8 1.2e-09 38.1 12.8 1.4 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 KLO16510.1 - 0.021 15.2 4.3 0.04 14.3 4.3 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal PCI PF01399.27 KLO16511.1 - 2.9e-09 37.4 0.0 6.7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain Hist_deacetyl PF00850.19 KLO16512.1 - 9.2e-61 206.0 0.0 1.2e-60 205.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF3916 PF13079.6 KLO16512.1 - 0.15 11.9 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3916) BTB PF00651.31 KLO16513.1 - 0.0011 19.2 0.1 0.02 15.1 0.1 2.9 3 1 0 3 3 3 1 BTB/POZ domain GATase_4 PF13230.6 KLO16513.1 - 0.07 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II MFS_1 PF07690.16 KLO16514.1 - 1.4e-38 132.8 44.8 4e-38 131.2 44.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily SieB PF14163.6 KLO16514.1 - 0.021 14.3 0.0 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 Super-infection exclusion protein B MFS_1 PF07690.16 KLO16515.1 - 6e-41 140.5 51.0 2.9e-39 135.0 48.4 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Chordopox_A13L PF05961.11 KLO16515.1 - 0.082 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein TMEM132D_C PF15706.5 KLO16515.1 - 0.35 10.7 1.4 26 4.7 0.1 2.8 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term P22_Cro PF14549.6 KLO16515.1 - 0.38 10.6 1.3 0.74 9.7 1.3 1.4 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro DUF4293 PF14126.6 KLO16515.1 - 5.6 7.2 7.7 5.3 7.3 2.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4293) STE3 PF02076.15 KLO16516.1 - 8.1e-110 366.6 20.6 9.5e-110 366.3 20.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor PSII PF00421.19 KLO16516.1 - 0.17 10.5 1.0 0.53 8.9 0.2 2.0 2 0 0 2 2 2 0 Photosystem II protein FeoB_associated PF12669.7 KLO16516.1 - 0.51 10.8 3.0 1.5 9.3 0.0 3.0 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein Pheromone PF08015.11 KLO16517.1 - 3.5e-08 34.4 1.0 5.7e-08 33.7 1.0 1.3 1 1 0 1 1 1 1 Fungal mating-type pheromone STE3 PF02076.15 KLO16518.1 - 9.9e-98 326.9 21.9 1.2e-97 326.7 21.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF4255 PF14065.6 KLO16519.1 - 0.0057 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4255) STE3 PF02076.15 KLO16520.1 - 2.9e-110 368.1 18.0 3.4e-110 367.8 18.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF1461 PF07314.11 KLO16520.1 - 0.39 10.6 3.0 0.4 10.6 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Abhydrolase_9_N PF15420.6 KLO16520.1 - 1.2 9.1 8.2 5.7 6.9 0.6 3.1 2 2 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus STE3 PF02076.15 KLO16521.1 - 2.3e-44 151.8 9.1 3.1e-44 151.3 9.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor VKOR PF07884.14 KLO16521.1 - 0.025 14.7 1.4 0.025 14.7 1.4 2.6 3 0 0 3 3 3 0 Vitamin K epoxide reductase family PDR_CDR PF06422.12 KLO16521.1 - 0.56 10.2 2.0 14 5.6 0.3 2.6 2 0 0 2 2 2 0 CDR ABC transporter CNOT11 PF10155.9 KLO16523.1 - 2.5e-16 59.9 0.0 6.1e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Pkinase PF00069.25 KLO16524.1 - 5.8e-70 235.7 0.5 1.3e-69 234.5 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16524.1 - 4.7e-51 173.6 0.3 2.8e-50 171.0 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 KLO16524.1 - 8.5e-24 83.7 0.0 2e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KLO16524.1 - 1.3e-05 24.7 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 KLO16524.1 - 1.9e-05 25.1 0.3 4.5e-05 23.9 0.3 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 KLO16524.1 - 4.9e-05 22.3 0.0 8.2e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KLO16524.1 - 8.1e-05 21.7 0.4 0.00013 21.0 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain PH_11 PF15413.6 KLO16524.1 - 0.024 15.1 0.2 0.22 12.0 0.2 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain APH PF01636.23 KLO16524.1 - 0.026 14.5 0.4 0.026 14.5 0.4 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KLO16524.1 - 0.045 12.8 0.1 0.094 11.8 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Forkhead_N PF08430.12 KLO16524.1 - 1.3 9.6 28.9 0.34 11.5 15.0 2.5 2 0 0 2 2 2 0 Forkhead N-terminal region Ribosomal_S19 PF00203.21 KLO16525.1 - 6.5e-27 93.2 0.0 8.6e-27 92.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Misat_Tub_SegII PF10644.9 KLO16527.1 - 6.2e-36 123.3 0.0 1.2e-35 122.4 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KLO16527.1 - 2.2e-30 105.7 0.0 4.2e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KLO16527.1 - 1.4e-05 25.4 0.0 0.02 15.1 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain SAP130_C PF16014.5 KLO16527.1 - 0.049 12.7 0.0 0.099 11.7 0.0 1.4 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus zf-MYND PF01753.18 KLO16528.1 - 2.1e-08 34.1 14.0 4.5e-08 33.0 14.0 1.6 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 KLO16528.1 - 0.12 12.7 4.4 0.34 11.3 4.4 1.7 1 0 0 1 1 1 0 Rhodanase C-terminal F-box-like PF12937.7 KLO16530.1 - 5.6e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF2046 PF09755.9 KLO16530.1 - 0.03 13.6 0.2 0.051 12.8 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) zf-MYND PF01753.18 KLO16531.1 - 1e-07 31.9 18.2 2.1e-07 30.9 18.2 1.5 1 0 0 1 1 1 1 MYND finger OTU PF02338.19 KLO16532.1 - 3e-13 50.4 0.0 6e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KLO16532.1 - 0.00064 19.2 0.0 0.86 9.0 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain Tim54 PF11711.8 KLO16532.1 - 0.0019 17.1 0.8 0.003 16.4 0.8 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.6 KLO16532.1 - 4.3 7.0 6.6 0.52 10.0 1.2 2.0 2 0 0 2 2 2 0 FAM176 family RPN2_C PF18004.1 KLO16532.1 - 6.4 6.7 7.8 6.6 6.6 1.2 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain AAA_11 PF13086.6 KLO16533.1 - 5.6e-55 186.9 0.2 8.2e-55 186.4 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KLO16533.1 - 3.1e-54 183.6 0.0 7.2e-54 182.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO16533.1 - 1.4e-13 51.5 0.2 6.6e-13 49.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KLO16533.1 - 2.2e-11 43.9 0.0 8.1e-07 29.0 0.0 2.7 1 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KLO16533.1 - 7.3e-06 25.9 0.1 1.4 8.6 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KLO16533.1 - 1e-05 25.2 3.9 6.8e-05 22.5 3.9 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Ufd2P_core PF10408.9 KLO16533.1 - 0.0011 17.7 0.1 0.0016 17.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core ATPase_2 PF01637.18 KLO16533.1 - 0.0018 18.2 0.2 0.006 16.5 0.0 1.9 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea OmpH PF03938.14 KLO16533.1 - 0.0026 18.1 3.4 0.0078 16.6 3.4 1.7 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) FapA PF03961.13 KLO16533.1 - 0.0037 15.9 3.7 0.0059 15.3 3.7 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A ResIII PF04851.15 KLO16533.1 - 0.0045 17.0 0.1 0.017 15.1 0.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit BshC PF10079.9 KLO16533.1 - 0.009 14.8 1.0 0.015 14.1 1.0 1.2 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC CLZ PF16526.5 KLO16533.1 - 0.01 16.2 2.1 0.026 14.9 2.1 1.7 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA PF00004.29 KLO16533.1 - 0.021 15.2 0.3 0.21 12.0 0.6 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD_C PF13361.6 KLO16533.1 - 0.022 14.1 0.2 0.73 9.2 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KLO16533.1 - 0.028 14.8 0.0 0.15 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_6 PF12774.7 KLO16533.1 - 0.039 12.9 0.1 0.091 11.7 0.1 1.5 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region DUF1664 PF07889.12 KLO16533.1 - 0.054 13.5 1.7 0.12 12.5 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Lipoprotein_7 PF01540.16 KLO16533.1 - 0.091 12.0 1.4 0.16 11.2 1.4 1.3 1 0 0 1 1 1 0 Adhesin lipoprotein AAA_7 PF12775.7 KLO16533.1 - 0.092 12.3 0.3 4.2 6.9 0.1 2.4 1 1 1 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KLO16533.1 - 0.13 12.5 0.0 0.53 10.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain ABC_tran_CTD PF16326.5 KLO16533.1 - 0.15 12.3 6.4 0.41 10.9 6.4 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain CENP-H PF05837.12 KLO16533.1 - 0.2 12.1 7.5 0.49 10.8 7.5 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Sipho_Gp157 PF05565.11 KLO16533.1 - 0.23 11.5 6.7 0.56 10.2 6.7 1.6 1 0 0 1 1 1 0 Siphovirus Gp157 Fzo_mitofusin PF04799.13 KLO16533.1 - 0.26 10.8 4.2 0.57 9.7 4.2 1.5 1 0 0 1 1 1 0 fzo-like conserved region Vps51 PF08700.11 KLO16533.1 - 0.3 11.2 2.6 3.8 7.7 0.5 3.0 2 1 0 2 2 2 0 Vps51/Vps67 TMPIT PF07851.13 KLO16533.1 - 0.4 9.9 3.8 0.62 9.2 3.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein HSBP1 PF06825.12 KLO16533.1 - 1 9.2 5.9 0.75 9.7 0.1 2.9 3 0 0 3 3 3 0 Heat shock factor binding protein 1 MFS_1 PF07690.16 KLO16534.1 - 2.1e-26 92.7 68.5 1.2e-21 77.0 44.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily HD PF01966.22 KLO16541.1 - 1.1e-05 25.7 0.0 1.6e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 HD domain 60KD_IMP PF02096.20 KLO16542.1 - 4.8e-19 68.9 0.6 6.9e-19 68.3 0.6 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Sugar_tr PF00083.24 KLO16543.1 - 8.1e-105 351.3 27.1 9.5e-105 351.1 27.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO16543.1 - 5.4e-28 97.9 25.6 5.4e-28 97.9 25.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KLO16543.1 - 1.4e-07 30.4 3.2 1.4e-07 30.4 3.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Nop53 PF07767.11 KLO16544.1 - 2.7e-79 267.4 21.9 3.1e-79 267.2 21.9 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF1501 PF07394.12 KLO16544.1 - 0.37 9.8 3.6 0.57 9.2 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) TSGP1 PF07771.11 KLO16544.1 - 9.3 6.4 7.7 0.59 10.3 2.4 1.7 2 0 0 2 2 2 0 Tick salivary peptide group 1 DUF5518 PF17647.1 KLO16546.1 - 0.0054 16.9 3.7 0.0054 16.9 3.7 3.5 4 0 0 4 4 4 2 Family of unknown function (DUF5518) Phage_holin_5_1 PF06946.11 KLO16546.1 - 0.1 13.0 0.6 3.7 8.0 0.0 2.9 2 1 1 3 3 3 0 Bacteriophage A118-like holin, Hol118 PDZ_1 PF12812.7 KLO16547.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 PDZ-like domain F-box-like PF12937.7 KLO16548.1 - 1.2e-05 25.1 0.6 6.9e-05 22.7 0.1 2.6 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KLO16548.1 - 0.0068 16.8 0.5 0.044 14.2 0.2 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) RHS_repeat PF05593.14 KLO16551.1 - 1.6e-21 76.4 53.7 0.00055 20.4 0.4 14.1 12 3 3 15 15 15 9 RHS Repeat VCBS PF13517.6 KLO16551.1 - 6.2e-09 36.3 11.4 3.1e-06 27.7 1.0 5.2 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SpvB PF03534.13 KLO16551.1 - 6.8e-09 35.3 5.3 7.9e-08 31.8 1.7 3.0 2 1 0 2 2 2 1 Salmonella virulence plasmid 65kDa B protein FG-GAP PF01839.23 KLO16551.1 - 0.00039 20.5 0.6 0.87 9.8 0.2 3.2 2 0 0 2 2 2 2 FG-GAP repeat RHS PF03527.14 KLO16551.1 - 0.0013 18.4 0.6 0.25 11.1 0.0 3.8 3 0 0 3 3 3 1 RHS protein Gly-zipper_YMGG PF13441.6 KLO16551.1 - 0.0057 16.4 6.4 0.0057 16.4 6.4 2.6 2 1 0 2 2 2 1 YMGG-like Gly-zipper Big_3_4 PF13754.6 KLO16551.1 - 0.093 12.5 0.0 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function F-box-like PF12937.7 KLO16552.1 - 0.0013 18.5 1.5 0.0013 18.5 1.5 2.2 2 0 0 2 2 2 1 F-box-like zf-MYND PF01753.18 KLO16552.1 - 0.0015 18.6 12.6 0.0015 18.6 12.6 2.4 3 0 0 3 3 3 1 MYND finger Pro_CA PF00484.19 KLO16553.1 - 5.7e-09 36.5 0.0 5.7e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.19 KLO16554.1 - 9.5e-09 35.7 0.3 3.1e-08 34.1 0.1 1.7 2 0 0 2 2 2 1 Carbonic anhydrase F-box-like PF12937.7 KLO16555.1 - 3.7e-05 23.5 0.8 7e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO16556.1 - 2.4e-05 24.1 0.4 0.00047 20.0 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO16556.1 - 0.032 14.1 0.2 0.28 11.1 0.0 2.5 2 0 0 2 2 2 0 F-box domain NTNH_C PF08470.10 KLO16556.1 - 0.2 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal F-box-like PF12937.7 KLO16557.1 - 7.7e-06 25.7 1.3 2.8e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO16558.1 - 3.4e-06 26.8 0.1 8.3e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like Phage_min_tail PF05939.13 KLO16558.1 - 0.061 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Phage minor tail protein BIR PF00653.21 KLO16559.1 - 0.029 15.0 0.5 0.073 13.7 0.5 1.7 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.8 KLO16559.1 - 0.045 14.1 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KLO16559.1 - 0.17 12.8 0.3 0.42 11.6 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO16559.1 - 0.19 12.3 0.1 0.49 11.0 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type EHN PF06441.12 KLO16560.1 - 2.4e-34 118.0 0.9 1.2e-33 115.7 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KLO16560.1 - 2.1e-10 40.7 0.1 3.3e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO16560.1 - 9.2e-05 23.1 1.5 0.00058 20.5 1.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ras PF00071.22 KLO16561.1 - 2e-49 167.3 0.0 2.3e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO16561.1 - 1.5e-24 86.5 0.0 2.1e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO16561.1 - 1.4e-07 31.2 0.0 2.2e-07 30.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KLO16561.1 - 0.0071 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KLO16561.1 - 0.013 15.9 0.1 0.035 14.5 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KLO16561.1 - 0.063 12.7 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein MMR_HSR1 PF01926.23 KLO16561.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KLO16561.1 - 0.14 11.8 0.1 3.1 7.5 0.1 2.1 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.20 KLO16561.1 - 0.23 10.6 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Aldedh PF00171.22 KLO16563.1 - 7.7e-179 595.0 0.2 8.7e-179 594.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KLO16563.1 - 0.0084 15.6 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) F-box-like PF12937.7 KLO16564.1 - 3.1e-06 27.0 5.4 3.2e-06 26.9 1.4 3.1 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 KLO16564.1 - 0.2 11.6 2.1 9.4 6.3 0.3 3.6 3 1 0 3 3 3 0 F-box domain TauD PF02668.16 KLO16565.1 - 3.9e-52 177.7 0.4 4.4e-52 177.5 0.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 KLO16566.1 - 2.6e-92 310.1 27.2 3e-92 309.9 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO16566.1 - 2.2e-25 89.3 30.2 2.2e-25 89.3 30.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO16567.1 - 5.9e-88 295.7 19.5 7.6e-88 295.3 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO16567.1 - 4e-22 78.6 49.3 2.2e-20 72.9 26.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Lyase_1 PF00206.20 KLO16568.1 - 3.8e-23 82.4 0.0 6.2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KLO16568.1 - 2.7e-19 69.5 0.0 9.5e-19 67.7 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Pkinase PF00069.25 KLO16569.1 - 8.1e-70 235.2 0.0 1.2e-69 234.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16569.1 - 5.9e-38 130.6 0.0 1e-37 129.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO16569.1 - 5.7e-07 29.1 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 KLO16569.1 - 0.00077 19.2 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KLO16569.1 - 0.0037 16.3 0.4 0.0078 15.2 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KLO16569.1 - 0.036 13.6 0.1 0.087 12.4 0.1 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KLO16569.1 - 0.065 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Integrase_H2C2 PF17921.1 KLO16570.1 - 2.4e-09 37.2 1.8 2.4e-09 37.2 1.8 2.3 2 1 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KLO16570.1 - 0.0065 16.7 0.5 0.018 15.2 0.5 1.8 1 0 0 1 1 1 1 H2C2 zinc finger SUI1 PF01253.22 KLO16572.1 - 2.5e-19 69.6 0.0 4.5e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KLO16572.1 - 5.3e-13 49.5 0.0 1.4e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KLO16572.1 - 6.5e-05 22.8 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 PUA domain Kin17_mid PF10357.9 KLO16572.1 - 0.11 12.4 0.8 0.23 11.4 0.8 1.5 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein zf-C2H2_4 PF13894.6 KLO16573.1 - 3.8e-12 45.9 39.3 0.0087 16.8 2.0 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO16573.1 - 1.2e-05 25.5 36.8 0.011 16.2 1.8 6.1 6 1 0 6 6 6 4 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 KLO16573.1 - 0.0032 17.3 9.3 0.035 14.0 0.0 3.8 4 0 0 4 4 4 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KLO16573.1 - 0.028 14.7 4.2 0.028 14.7 4.2 6.1 6 2 0 6 6 6 0 Zinc-finger double-stranded RNA-binding HNH_5 PF14279.6 KLO16573.1 - 0.059 13.2 6.6 21 5.1 0.2 4.1 3 1 1 4 4 4 0 HNH endonuclease DUF2318 PF10080.9 KLO16573.1 - 0.42 10.8 6.9 1.6 8.9 0.2 3.5 3 1 1 4 4 4 0 Predicted membrane protein (DUF2318) zinc_ribbon_10 PF10058.9 KLO16573.1 - 0.58 9.9 8.3 0.49 10.2 0.5 2.7 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF3398 PF11878.8 KLO16573.1 - 2.3 8.7 5.0 8.3 6.9 0.1 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF3398) zf-met PF12874.7 KLO16573.1 - 3.8 8.0 25.4 0.97 9.9 2.2 4.5 6 0 0 6 6 6 0 Zinc-finger of C2H2 type DZR PF12773.7 KLO16573.1 - 6.6 6.8 12.6 2.6e+03 -1.5 12.6 2.9 1 1 0 1 1 1 0 Double zinc ribbon HMG_box PF00505.19 KLO16574.1 - 1.5e-22 79.8 0.4 2.6e-22 79.0 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO16574.1 - 1.6e-17 63.8 1.0 2.9e-17 63.0 1.0 1.4 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 KLO16574.1 - 0.002 18.0 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain zf-C2H2_4 PF13894.6 KLO16575.1 - 8.9e-06 26.1 37.1 0.67 11.0 1.0 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO16575.1 - 0.03 14.8 34.6 1.8 9.2 1.9 5.8 5 1 1 6 6 6 0 Zinc finger, C2H2 type zf_UBZ PF18439.1 KLO16575.1 - 0.098 12.3 24.2 0.1 12.2 3.2 4.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KLO16575.1 - 2.1 8.9 17.7 13 6.4 0.3 5.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-P11 PF03854.14 KLO16575.1 - 2.4 7.9 0.0 2.4 7.9 0.0 3.9 5 0 0 5 5 5 0 P-11 zinc finger DUF1272 PF06906.11 KLO16575.1 - 2.8 8.1 9.3 2.3 8.4 1.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) A2L_zn_ribbon PF08792.10 KLO16575.1 - 9.1 6.1 9.1 3.4 7.5 0.0 3.6 4 0 0 4 4 4 0 A2L zinc ribbon domain zinc-ribbons_6 PF07191.12 KLO16575.1 - 9.6 6.3 18.1 1.2e+02 2.8 2.1 4.2 2 2 0 2 2 2 0 zinc-ribbons zf-C2H2_4 PF13894.6 KLO16576.1 - 1.8e-15 56.3 50.5 0.047 14.5 0.8 10.2 10 0 0 10 10 10 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KLO16576.1 - 3e-15 55.7 49.2 0.014 15.8 0.2 9.8 8 2 2 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KLO16576.1 - 4.9e-10 39.4 51.5 9.6e-05 22.6 5.5 8.6 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KLO16576.1 - 2.2e-08 34.2 31.5 0.0013 19.0 2.6 8.2 9 0 0 9 9 9 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KLO16576.1 - 8.9e-05 22.4 40.7 0.0011 19.0 0.4 7.9 8 0 0 8 8 8 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KLO16576.1 - 0.00067 19.9 37.1 0.15 12.4 0.1 5.0 2 1 2 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-trcl PF13451.6 KLO16576.1 - 0.038 13.9 3.1 0.038 13.9 3.1 5.2 6 1 0 6 6 6 0 Probable zinc-ribbon domain zf-H2C2_2 PF13465.6 KLO16576.1 - 0.5 10.9 0.0 0.5 10.9 0.0 8.6 8 1 0 8 8 8 0 Zinc-finger double domain DUF2318 PF10080.9 KLO16576.1 - 3 8.0 16.5 18 5.5 0.0 5.4 4 1 2 6 6 6 0 Predicted membrane protein (DUF2318) Zn-ribbon_8 PF09723.10 KLO16576.1 - 9.6 6.4 33.4 9.9 6.4 0.2 7.7 5 1 3 8 8 8 0 Zinc ribbon domain Oxysterol_BP PF01237.18 KLO16577.1 - 1.6e-58 198.4 1.0 4.4e-56 190.3 1.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein TGF_beta_GS PF08515.12 KLO16578.1 - 0.61 9.6 3.3 1.2 8.7 0.7 2.5 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Pro_CA PF00484.19 KLO16579.1 - 4.2e-33 114.9 0.5 5.6e-33 114.5 0.5 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Eno-Rase_NADH_b PF12242.8 KLO16579.1 - 0.18 11.6 0.3 22 4.9 0.0 2.6 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pro_CA PF00484.19 KLO16580.1 - 6.1e-31 107.8 0.2 1.1e-30 107.0 0.2 1.4 1 1 0 1 1 1 1 Carbonic anhydrase Aminotran_4 PF01063.19 KLO16581.1 - 8.1e-28 97.8 0.0 1.5e-27 97.0 0.0 1.3 1 1 0 1 1 1 1 Amino-transferase class IV Mito_carr PF00153.27 KLO16582.1 - 3.9e-61 203.0 2.4 8.7e-21 73.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KLO16582.1 - 2.3 8.6 7.6 20 5.6 3.1 3.4 2 2 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family FMO-like PF00743.19 KLO16583.1 - 6.1e-24 84.3 0.0 3.1e-20 72.1 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KLO16583.1 - 2.1e-23 83.0 0.0 4e-22 78.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KLO16583.1 - 1.3e-14 54.1 0.0 1.1e-10 41.2 0.0 2.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KLO16583.1 - 1.1e-11 44.5 0.0 2.7e-07 30.1 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KLO16583.1 - 2.2e-06 27.7 0.1 0.033 14.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 KLO16583.1 - 1.2e-05 25.8 0.3 0.028 15.0 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KLO16583.1 - 3.1e-05 24.0 0.2 0.025 14.6 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KLO16583.1 - 0.0015 18.7 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KLO16583.1 - 0.002 18.5 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.14 KLO16583.1 - 0.0028 16.4 0.1 0.013 14.2 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein TrkA_N PF02254.18 KLO16583.1 - 0.003 17.8 0.1 0.031 14.5 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain DAO PF01266.24 KLO16583.1 - 0.003 17.2 2.0 0.22 11.1 0.1 3.3 2 2 1 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KLO16583.1 - 0.0075 15.4 0.3 0.051 12.6 0.0 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein GIDA PF01134.22 KLO16583.1 - 0.0081 15.3 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 KLO16583.1 - 0.02 14.3 0.0 0.33 10.3 0.0 2.4 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KLO16583.1 - 0.024 13.9 0.1 0.087 12.1 0.0 1.9 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 KLO16583.1 - 0.025 13.7 0.1 0.084 11.9 0.0 1.9 3 0 0 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.19 KLO16583.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FMO-like PF00743.19 KLO16584.1 - 1.3e-25 89.9 0.0 1.7e-20 73.0 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KLO16584.1 - 8.3e-22 77.8 0.0 6.4e-20 71.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KLO16584.1 - 2.1e-12 46.9 0.0 2.8e-08 33.4 0.0 2.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KLO16584.1 - 2.1e-11 43.5 0.0 2e-07 30.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KLO16584.1 - 5.9e-06 26.4 0.1 0.065 13.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KLO16584.1 - 0.00038 20.5 1.0 0.28 11.2 0.0 2.7 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KLO16584.1 - 0.0013 18.4 0.5 0.83 9.2 0.0 3.4 3 1 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO16584.1 - 0.0013 19.0 0.0 0.0044 17.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KLO16584.1 - 0.0019 17.0 0.1 0.036 12.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KLO16584.1 - 0.0042 17.6 0.1 0.19 12.3 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SnoaL_2 PF12680.7 KLO16584.1 - 0.0063 17.1 0.0 0.021 15.5 0.0 1.9 1 0 0 1 1 1 1 SnoaL-like domain TrkA_N PF02254.18 KLO16584.1 - 0.0063 16.8 0.0 0.025 14.9 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.12 KLO16584.1 - 0.042 12.9 0.0 0.33 9.9 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 KLO16584.1 - 0.044 12.9 0.1 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KLO16584.1 - 0.087 11.9 0.0 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 KLO16584.1 - 0.15 12.5 0.0 5.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Kelch_4 PF13418.6 KLO16585.1 - 9.7e-46 153.6 8.6 3.5e-08 33.3 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 KLO16585.1 - 2.3e-40 135.9 6.4 7.6e-08 31.8 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KLO16585.1 - 6e-35 118.4 12.9 2.2e-08 34.1 0.1 6.3 3 2 3 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KLO16585.1 - 8.4e-34 115.0 7.5 2.7e-06 27.2 0.1 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KLO16585.1 - 3.6e-32 110.0 20.5 7.4e-08 32.5 0.1 7.4 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KLO16585.1 - 2.5e-24 84.3 7.8 0.0011 18.9 0.0 6.3 6 0 0 6 6 6 6 Kelch motif PQQ_3 PF13570.6 KLO16585.1 - 0.0013 19.1 4.7 28 5.4 0.0 5.5 6 0 0 6 6 6 0 PQQ-like domain ADK_lid PF05191.14 KLO16587.1 - 0.1 12.6 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid tRNA-synt_1 PF00133.22 KLO16588.1 - 4.3e-37 127.7 0.0 5.3e-27 94.3 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KLO16588.1 - 7e-15 55.3 0.0 1.8e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KLO16588.1 - 1.3e-14 53.7 0.0 7.9e-08 31.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KLO16588.1 - 1.2e-10 41.2 0.0 3.6e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KLO16588.1 - 0.036 13.0 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) GDPD PF03009.17 KLO16588.1 - 0.15 11.8 0.1 0.41 10.3 0.1 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family PseudoU_synth_1 PF01416.20 KLO16589.1 - 1.2e-20 74.0 0.0 3.4e-19 69.3 0.0 2.9 2 1 0 2 2 2 1 tRNA pseudouridine synthase Peptidase_C65 PF10275.9 KLO16590.1 - 2.1e-61 207.5 0.0 2.4e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 KLO16590.1 - 0.0038 17.7 0.0 0.22 12.0 0.0 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease WD40 PF00400.32 KLO16591.1 - 9.7e-36 121.2 20.0 1.6e-07 31.9 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO16591.1 - 4.1e-07 30.2 2.0 0.4 11.0 0.0 4.9 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KLO16591.1 - 5.4e-07 28.6 4.3 0.24 10.0 0.1 4.8 2 1 2 5 5 5 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KLO16591.1 - 7.5e-06 25.9 0.2 5.7 7.0 0.0 4.5 3 2 2 5 5 5 3 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 KLO16591.1 - 3e-05 24.3 7.7 5.4 7.6 0.0 6.3 5 1 1 6 6 6 2 PQQ-like domain PQQ_2 PF13360.6 KLO16591.1 - 0.00013 21.6 6.5 0.17 11.5 0.2 3.3 1 1 1 3 3 3 2 PQQ-like domain Nucleoporin_N PF08801.11 KLO16591.1 - 0.0016 17.3 0.6 1.2 7.9 0.0 4.2 2 2 3 5 5 5 1 Nup133 N terminal like PALB2_WD40 PF16756.5 KLO16591.1 - 0.0031 16.5 1.6 0.69 8.8 0.1 3.6 2 1 3 5 5 5 1 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 KLO16591.1 - 0.012 15.0 0.0 1.5 8.0 0.0 2.4 2 1 0 2 2 2 0 WD40-like domain DUF4784 PF16023.5 KLO16591.1 - 0.1 11.5 0.0 0.79 8.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4784) SNF2_N PF00176.23 KLO16592.1 - 4.2e-42 144.1 0.0 6.1e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO16592.1 - 8e-22 77.7 0.0 1.1e-19 70.8 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO16592.1 - 3.5e-05 23.9 0.0 0.00027 21.0 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KLO16592.1 - 5.7e-05 22.4 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 KLO16592.1 - 0.023 14.4 0.1 0.31 10.7 0.0 2.6 3 0 0 3 3 3 0 SWI2/SNF2 ATPase VIGSSK PF14773.6 KLO16592.1 - 0.067 13.3 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 Helicase-associated putative binding domain, C-terminal RNA_pol_Rpb2_6 PF00562.28 KLO16593.1 - 7.9e-126 420.2 0.3 1.1e-125 419.8 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KLO16593.1 - 1.3e-56 191.3 0.0 2.4e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KLO16593.1 - 4.2e-32 110.4 0.1 1e-31 109.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KLO16593.1 - 1.5e-29 103.0 0.0 3.6e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KLO16593.1 - 2.8e-25 88.4 3.8 4.5e-25 87.7 1.9 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KLO16593.1 - 3.4e-20 72.0 0.0 7.5e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KLO16593.1 - 7.4e-09 36.0 2.5 3.1e-08 34.0 2.5 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 TipE PF16972.5 KLO16594.1 - 0.0086 15.3 0.2 0.014 14.6 0.2 1.3 1 0 0 1 1 1 1 Na+ channel auxiliary subunit TipE TMEM100 PF16311.5 KLO16594.1 - 0.44 10.1 2.7 0.91 9.1 0.0 2.5 3 0 0 3 3 3 0 Transmembrane protein 100 Serpentine_r_xa PF03383.15 KLO16594.1 - 5.7 6.9 10.4 6.7 6.7 3.4 2.4 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa TipE PF16972.5 KLO16595.1 - 0.0077 15.5 0.2 0.013 14.7 0.2 1.4 1 0 0 1 1 1 1 Na+ channel auxiliary subunit TipE TMEM100 PF16311.5 KLO16595.1 - 1.3 8.6 0.0 1.3 8.6 0.0 2.4 3 0 0 3 3 3 0 Transmembrane protein 100 But2 PF09792.9 KLO16596.1 - 3.8e-05 24.1 0.0 9.9e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain 7TM_GPCR_Srv PF10323.9 KLO16596.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF3328 PF11807.8 KLO16598.1 - 5.6e-08 32.8 4.8 9.9e-08 32.0 2.2 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KLO16599.1 - 9.7e-11 41.9 0.0 1.2e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TipE PF16972.5 KLO16600.1 - 0.0012 18.1 0.3 0.0022 17.3 0.3 1.3 1 0 0 1 1 1 1 Na+ channel auxiliary subunit TipE Peptidase_M17 PF00883.21 KLO16601.1 - 8.5e-109 363.6 0.0 1.2e-108 363.1 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF2487 PF10673.9 KLO16601.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) EAP30 PF04157.16 KLO16602.1 - 3.8e-31 108.2 0.0 5e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KLO16602.1 - 3.6e-13 49.5 0.0 4.3e-12 46.0 0.0 2.2 1 1 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 KLO16602.1 - 0.0017 17.7 8.9 0.026 13.8 1.2 2.6 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 KLO16602.1 - 0.36 10.3 7.7 0.28 10.6 0.3 3.0 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 KLO16602.1 - 0.68 10.0 6.7 3.4 7.8 0.0 3.2 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger DZR PF12773.7 KLO16602.1 - 0.74 9.9 4.6 1.1 9.3 0.4 2.3 2 0 0 2 2 2 0 Double zinc ribbon IMPDH PF00478.25 KLO16603.1 - 8.1e-129 429.5 0.0 1.2e-126 422.4 0.0 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KLO16603.1 - 4e-10 40.0 0.1 0.0016 18.8 0.1 2.8 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KLO16603.1 - 7.7e-10 38.3 1.0 2.9e-09 36.4 1.5 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KLO16603.1 - 2e-05 24.2 9.9 7.3e-05 22.3 8.2 2.3 2 1 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KLO16603.1 - 4.2e-05 23.1 4.2 0.0002 20.9 2.3 2.6 2 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KLO16603.1 - 4.4e-05 22.9 1.9 8.8e-05 21.9 1.4 1.8 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KLO16603.1 - 0.037 13.2 2.8 0.19 10.9 0.7 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 KLO16603.1 - 0.053 12.6 2.5 0.1 11.7 2.5 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase G3P_antiterm PF04309.12 KLO16603.1 - 0.2 11.0 0.7 1.8 7.9 0.2 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Spt20 PF12090.8 KLO16604.1 - 5.8 6.5 21.6 5.8 6.5 21.6 1.0 1 0 0 1 1 1 0 Spt20 family UQ_con PF00179.26 KLO16605.1 - 2.3e-44 150.4 0.0 2.7e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MT-A70 PF05063.14 KLO16606.1 - 2.9e-40 138.0 0.0 5.5e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 MT-A70 Noc2 PF03715.13 KLO16607.1 - 2.6e-111 371.6 0.0 4e-111 371.0 0.0 1.3 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 KLO16607.1 - 0.13 10.4 37.5 1.1 7.4 0.0 2.9 2 1 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 KLO16607.1 - 5.4 6.2 26.7 11 5.2 26.7 1.5 1 0 0 1 1 1 0 BUD22 F-box-like PF12937.7 KLO16609.1 - 0.00035 20.4 0.4 0.0041 17.0 0.5 2.4 2 0 0 2 2 2 1 F-box-like Ppx-GppA PF02541.16 KLO16609.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family F-box-like PF12937.7 KLO16610.1 - 1.2e-06 28.3 2.8 9.8e-06 25.4 1.0 2.8 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO16610.1 - 0.075 12.9 0.7 21 5.1 0.0 3.6 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO16611.1 - 9.5e-07 28.6 0.9 1.3e-05 24.9 0.9 2.5 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO16611.1 - 0.87 10.1 6.1 86 3.8 1.8 5.0 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Dynamin_N PF00350.23 KLO16612.1 - 1.4e-28 100.0 1.0 1.5e-27 96.7 0.2 2.9 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KLO16612.1 - 3.2e-27 95.5 0.0 1.8e-12 47.1 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KLO16612.1 - 1.5e-08 34.7 1.6 4.4e-08 33.2 1.6 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KLO16612.1 - 0.0006 19.9 0.8 0.0058 16.7 0.8 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KLO16612.1 - 0.089 13.2 0.4 1.2 9.5 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_28 PF13521.6 KLO16612.1 - 0.37 11.0 3.6 0.64 10.3 0.4 2.8 3 0 0 3 3 3 0 AAA domain HAS-barrel PF09378.10 KLO16613.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 HAS barrel domain FAD_binding_4 PF01565.23 KLO16614.1 - 6.8e-29 100.4 3.1 1.1e-28 99.7 3.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KLO16614.1 - 3.2e-08 33.6 0.1 5.3e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like STE PF02200.16 KLO16620.1 - 7.7e-53 177.6 0.0 1.3e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KLO16620.1 - 4.6e-09 36.2 12.5 1.8e-05 24.9 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO16620.1 - 2.1e-06 28.1 9.5 0.0043 17.8 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KLO16620.1 - 4.9e-06 26.7 2.6 4.9e-06 26.7 2.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KLO16620.1 - 0.00043 20.2 0.4 0.00043 20.2 0.4 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KLO16620.1 - 0.00099 19.4 0.5 0.0035 17.6 0.5 1.9 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 KLO16620.1 - 0.026 14.9 5.7 0.029 14.7 0.7 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KLO16620.1 - 0.029 14.6 3.9 1.4 9.3 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KLO16620.1 - 0.86 10.1 6.2 1.4 9.5 1.7 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger ThrE PF06738.12 KLO16622.1 - 0.068 12.5 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF1687 PF07955.11 KLO16623.1 - 4e-15 56.4 0.0 5.4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) CRF1 PF10380.9 KLO16623.1 - 0.063 13.6 0.8 0.14 12.5 0.6 1.8 1 1 1 2 2 2 0 Transcription factor CRF1 Sde2_N_Ubi PF13019.6 KLO16623.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.3 1 1 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain F-box-like PF12937.7 KLO16624.1 - 7.5e-05 22.6 4.0 0.14 12.1 2.9 2.6 2 0 0 2 2 2 2 F-box-like LRR_9 PF14580.6 KLO16624.1 - 0.086 12.3 0.4 0.18 11.3 0.4 1.6 1 0 0 1 1 1 0 Leucine-rich repeat LRR_4 PF12799.7 KLO16624.1 - 1.1 9.7 14.0 6 7.4 0.4 5.8 3 1 5 8 8 8 0 Leucine Rich repeats (2 copies) Aa_trans PF01490.18 KLO16625.1 - 5.9e-28 97.7 41.8 1e-27 96.9 41.8 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein zf-MYND PF01753.18 KLO16626.1 - 7.8e-09 35.5 13.0 7.8e-09 35.5 13.0 1.9 2 0 0 2 2 2 1 MYND finger Dynamin_M PF01031.20 KLO16628.1 - 1e-31 110.3 0.2 8e-15 54.8 0.0 2.8 4 0 0 4 4 4 2 Dynamin central region Dynamin_N PF00350.23 KLO16628.1 - 1.6e-25 90.1 0.0 3.7e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KLO16628.1 - 4.3e-08 33.2 1.1 1.3e-07 31.6 1.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KLO16628.1 - 0.00045 20.3 0.0 0.0064 16.6 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KLO16628.1 - 0.056 13.1 0.2 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF677 PF05055.12 KLO16629.1 - 7.6e-06 25.0 0.2 2.2e-05 23.5 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF677) DUF3040 PF11239.8 KLO16629.1 - 0.00079 19.7 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) Claudin_2 PF13903.6 KLO16629.1 - 0.0079 16.0 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2721 PF11026.8 KLO16629.1 - 0.0083 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) DUF2207 PF09972.9 KLO16629.1 - 0.015 14.1 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TelA PF05816.11 KLO16629.1 - 0.017 14.2 0.4 0.14 11.2 0.2 1.9 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) DUF1664 PF07889.12 KLO16629.1 - 0.023 14.7 1.5 0.15 12.1 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 KLO16629.1 - 0.031 14.2 1.1 2.1 8.2 0.4 2.9 2 1 1 3 3 3 0 Sec34-like family DUF5446 PF17522.2 KLO16629.1 - 0.044 13.9 0.4 0.12 12.6 0.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5446) ATG16 PF08614.11 KLO16629.1 - 0.065 13.5 1.1 9.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) INT_SG_DDX_CT_C PF15300.6 KLO16629.1 - 0.077 12.8 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Cluap1 PF10234.9 KLO16629.1 - 0.08 12.3 0.6 0.11 11.8 0.6 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 SseC PF04888.12 KLO16629.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF2628 PF10947.8 KLO16629.1 - 0.14 12.5 0.6 0.3 11.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) ETRAMP PF09716.10 KLO16629.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TOPRIM_C PF16898.5 KLO16629.1 - 0.18 12.1 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM DUF3176 PF11374.8 KLO16632.1 - 0.019 15.2 6.3 0.29 11.3 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) TPR_9 PF13371.6 KLO16634.1 - 0.00067 19.8 1.3 0.0016 18.6 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KLO16634.1 - 0.0013 18.7 0.0 0.0038 17.2 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KLO16634.1 - 0.0047 16.7 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KLO16634.1 - 0.011 16.4 0.3 0.011 16.4 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KLO16634.1 - 0.014 16.0 0.0 0.058 14.0 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KLO16634.1 - 0.029 14.6 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Suf PF05843.14 KLO16634.1 - 1.6 8.7 12.9 0.22 11.5 5.3 2.7 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) FeoB_C PF07664.12 KLO16635.1 - 1.4 8.7 4.5 4.5 7.1 0.4 2.9 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus DUF3176 PF11374.8 KLO16636.1 - 0.0082 16.3 1.2 0.016 15.4 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) SpoIIM PF01944.17 KLO16636.1 - 0.18 11.8 3.6 0.33 11.0 3.6 1.4 1 0 0 1 1 1 0 Stage II sporulation protein M Tyr-DNA_phospho PF06087.12 KLO16637.1 - 2.7e-57 194.6 0.0 4.3e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KLO16637.1 - 1e-05 25.1 9.5 2.4e-05 23.9 1.4 3.0 2 0 0 2 2 2 2 Ubiquitin interaction motif PLDc_2 PF13091.6 KLO16637.1 - 0.067 13.1 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 PLD-like domain SARAF PF06682.12 KLO16637.1 - 2.2 7.9 8.8 0.1 12.2 3.1 1.6 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Peptidase_S31 PF05578.12 KLO16638.1 - 0.13 11.8 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 DUF3176 PF11374.8 KLO16639.1 - 3.9e-05 23.8 10.8 0.00088 19.4 0.9 3.7 3 1 1 4 4 4 2 Protein of unknown function (DUF3176) DUF3176 PF11374.8 KLO16640.1 - 0.016 15.4 14.9 0.084 13.1 1.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3176) DUF3325 PF11804.8 KLO16640.1 - 2 8.6 8.0 41 4.4 5.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) DUF3176 PF11374.8 KLO16641.1 - 0.27 11.5 5.0 0.34 11.1 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) GPI-anchored PF10342.9 KLO16642.1 - 0.0079 16.9 0.0 0.016 16.0 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TetR_C_28 PF17937.1 KLO16642.1 - 0.084 13.3 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain GST_N PF02798.20 KLO16644.1 - 4.6e-19 68.5 0.0 8.3e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KLO16644.1 - 8.4e-14 51.8 0.0 1.4e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO16644.1 - 4.4e-11 42.8 0.0 8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KLO16644.1 - 1.9e-08 34.5 0.0 3.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO16644.1 - 0.00011 22.1 0.0 0.00025 21.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO16644.1 - 0.001 19.2 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 KLO16644.1 - 0.021 15.2 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Xpo1 PF08389.12 KLO16646.1 - 3.5e-12 46.6 0.1 7.8e-09 35.7 0.0 3.9 3 1 1 4 4 4 2 Exportin 1-like protein Importin_rep PF18773.1 KLO16646.1 - 1.6e-10 40.5 0.1 3.4e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 KLO16646.1 - 2.4e-06 27.5 0.1 1.3e-05 25.1 0.1 2.4 1 0 0 1 1 1 1 Importin 13 repeat IBN_N PF03810.19 KLO16646.1 - 0.00012 21.9 0.0 0.00045 20.1 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Noc2 PF03715.13 KLO16646.1 - 0.021 14.1 0.7 0.66 9.2 0.0 2.4 2 0 0 2 2 2 0 Noc2p family DUF1539 PF07560.11 KLO16646.1 - 0.12 12.4 0.8 64 3.6 0.0 3.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) Arm PF00514.23 KLO16646.1 - 0.17 12.0 2.0 12 6.1 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Aconitase PF00330.20 KLO16647.1 - 1.1e-153 512.6 0.0 1.4e-153 512.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KLO16647.1 - 1.3e-42 145.2 0.0 2.2e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain UCR_hinge PF02320.16 KLO16648.1 - 4.3e-23 81.3 5.5 4.3e-23 81.3 5.5 1.6 2 1 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein ORC_WH_C PF18137.1 KLO16648.1 - 0.023 14.8 1.7 0.034 14.2 1.7 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF4718 PF15842.5 KLO16648.1 - 0.043 13.6 0.6 0.046 13.5 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) FAM176 PF14851.6 KLO16648.1 - 0.11 12.2 3.7 0.12 12.1 3.7 1.1 1 0 0 1 1 1 0 FAM176 family Evr1_Alr PF04777.13 KLO16648.1 - 0.95 10.0 4.0 1.7 9.2 0.9 2.1 1 1 1 2 2 2 0 Erv1 / Alr family DNA_pol_phi PF04931.13 KLO16648.1 - 2 6.4 8.7 2 6.4 8.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi PMSR PF01625.21 KLO16649.1 - 6.8e-63 211.4 1.6 9.8e-63 210.9 1.6 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Pkinase_Tyr PF07714.17 KLO16650.1 - 1.2e-48 165.7 0.0 1.7e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO16650.1 - 4.4e-47 160.6 0.0 6.7e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.22 KLO16650.1 - 1.1e-07 31.6 1.6 2.2e-07 30.6 1.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.14 KLO16650.1 - 0.0018 17.7 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO16650.1 - 0.0026 17.7 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PHD PF00628.29 KLO16650.1 - 0.038 13.9 2.0 0.074 12.9 2.0 1.4 1 0 0 1 1 1 0 PHD-finger Pkinase_fungal PF17667.1 KLO16650.1 - 0.069 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KLO16650.1 - 0.076 11.9 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KLO16650.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like C1_2 PF03107.16 KLO16650.1 - 0.3 11.4 1.2 0.58 10.5 1.2 1.5 1 0 0 1 1 1 0 C1 domain Prok-RING_1 PF14446.6 KLO16650.1 - 8.4 6.4 6.0 3.3 7.7 3.3 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Transp_cyt_pur PF02133.15 KLO16652.1 - 1.7e-110 369.8 36.1 2e-110 369.6 36.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase_Tyr PF07714.17 KLO16653.1 - 1.2e-62 211.6 0.0 7.5e-39 133.6 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KLO16653.1 - 6.8e-50 169.9 0.0 3.5e-34 118.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KLO16653.1 - 0.056 12.7 0.0 0.28 10.5 0.0 2.0 2 1 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 KLO16653.1 - 0.12 11.4 0.1 0.12 11.4 0.1 2.3 3 0 0 3 3 3 0 Seadornavirus VP7 ADH_zinc_N PF00107.26 KLO16654.1 - 5.6e-19 68.4 0.0 1.1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO16654.1 - 4.7e-10 40.6 0.0 9.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO16654.1 - 5.1e-08 32.8 0.0 8.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KLO16654.1 - 4.4e-05 23.1 0.1 7.1e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_2 PF16884.5 KLO16654.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Pkinase PF00069.25 KLO16655.1 - 5.2e-39 134.2 0.0 8e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16655.1 - 1.3e-37 129.5 0.0 4.8e-37 127.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO16655.1 - 6.5e-07 28.5 0.2 8.8e-07 28.0 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KLO16655.1 - 0.00066 19.3 0.0 0.0018 17.9 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KLO16655.1 - 0.0048 16.8 0.1 0.0094 15.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 KLO16655.1 - 0.012 15.8 0.0 0.041 14.0 0.0 1.9 2 0 0 2 2 2 0 ABC1 family Kinase-like PF14531.6 KLO16655.1 - 0.028 13.7 0.0 0.089 12.1 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Transp_cyt_pur PF02133.15 KLO16656.1 - 1.6e-30 106.3 40.8 2.5e-30 105.7 40.5 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3176 PF11374.8 KLO16658.1 - 0.013 15.7 0.8 0.034 14.3 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) Pkinase_Tyr PF07714.17 KLO16659.1 - 7.7e-62 208.9 0.0 3.6e-37 128.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KLO16659.1 - 8e-50 169.7 0.0 1.3e-32 113.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KLO16659.1 - 0.022 14.7 0.0 0.066 13.1 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Nup192 PF11894.8 KLO16660.1 - 8.9e-225 749.2 0.0 1.2e-224 748.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Got1 PF04178.12 KLO16661.1 - 7.2e-33 113.4 14.8 1.1e-32 112.8 14.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family AgrB PF04647.15 KLO16661.1 - 0.0024 17.2 6.5 0.0035 16.7 6.5 1.2 1 0 0 1 1 1 1 Accessory gene regulator B DUF2207 PF09972.9 KLO16661.1 - 0.084 11.6 3.0 0.19 10.5 3.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TM_helix PF05552.12 KLO16661.1 - 0.13 12.3 2.1 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 Conserved TM helix RPN5_C PF18098.1 KLO16661.1 - 0.16 12.1 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain DUF2070 PF09843.9 KLO16661.1 - 0.39 9.0 8.7 0.45 8.8 8.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF456 PF04306.13 KLO16661.1 - 0.69 10.2 13.4 0.19 12.0 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF456) ATP_sub_h PF10775.9 KLO16662.1 - 3.9e-20 71.6 1.0 5.5e-20 71.1 1.0 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h BTB_2 PF02214.22 KLO16664.1 - 0.014 15.7 0.1 0.081 13.3 0.0 2.2 2 1 0 2 2 2 0 BTB/POZ domain BTB PF00651.31 KLO16664.1 - 0.021 15.1 0.0 0.033 14.4 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain RNA_pol PF00940.19 KLO16665.1 - 2.3e-179 596.6 0.1 3.2e-179 596.1 0.1 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KLO16665.1 - 2.1e-95 320.0 1.6 2.1e-95 320.0 1.6 1.6 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 KLO16665.1 - 0.0034 17.5 0.0 0.0081 16.3 0.0 1.6 1 0 0 1 1 1 1 PPR repeat family Tho2 PF11262.8 KLO16665.1 - 0.041 13.1 0.2 0.44 9.7 0.1 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Coa1 PF08695.10 KLO16665.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Peptidase_M28 PF04389.17 KLO16666.1 - 1.3e-25 90.3 0.0 1.9e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KLO16666.1 - 1.8e-06 27.8 0.0 3.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KLO16666.1 - 0.0081 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Nicastrin Acetyltransf_1 PF00583.25 KLO16667.1 - 1.9e-15 57.1 0.0 2.5e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KLO16667.1 - 5.6e-09 36.0 0.0 8.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO16667.1 - 1.1e-08 35.4 0.0 1.6e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO16667.1 - 1.5e-07 31.2 0.1 2.7e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KLO16667.1 - 4.8e-05 24.0 0.0 6.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KLO16667.1 - 0.00037 20.6 0.0 0.0006 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KLO16667.1 - 0.00038 20.2 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KLO16667.1 - 0.0011 19.1 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KLO16667.1 - 0.033 14.3 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HSP70 PF00012.20 KLO16668.1 - 2.3e-262 871.6 7.7 2.6e-262 871.4 7.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KLO16668.1 - 1.5e-17 63.4 0.5 1.4e-16 60.3 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 KLO16668.1 - 0.0015 17.6 0.5 0.088 11.8 0.2 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KLO16668.1 - 0.04 13.2 0.2 0.11 11.7 0.2 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase HOIP-UBA PF16678.5 KLO16668.1 - 0.054 13.5 1.7 0.1 12.6 0.0 2.3 3 0 0 3 3 3 0 HOIP UBA domain pair RGS12_us2 PF16611.5 KLO16668.1 - 0.087 13.2 0.3 0.32 11.4 0.3 1.9 1 0 0 1 1 1 0 Unstructured region between RBD and GoLoco DUF3153 PF11353.8 KLO16668.1 - 0.11 12.1 0.4 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) CENP-Q PF13094.6 KLO16668.1 - 1.5 9.0 5.6 14 5.8 0.2 2.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Rtt106 PF08512.12 KLO16669.1 - 3.9e-17 62.4 0.0 9.2e-17 61.2 0.0 1.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Peptidase_U40 PF10464.9 KLO16669.1 - 0.04 13.6 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase U40 PH_18 PF18469.1 KLO16669.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain BTB PF00651.31 KLO16670.1 - 0.00029 21.1 1.4 0.00056 20.1 0.2 2.1 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO16672.1 - 1.7e-05 25.0 0.1 6.6e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 BTB/POZ domain GF_recep_IV PF14843.6 KLO16672.1 - 0.00041 20.2 0.1 0.00065 19.5 0.1 1.2 1 0 0 1 1 1 1 Growth factor receptor domain IV BTB PF00651.31 KLO16673.1 - 2.1e-05 24.7 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain RasGEF_N_2 PF14663.6 KLO16674.1 - 0.21 12.0 0.0 0.31 11.5 0.0 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain BTB PF00651.31 KLO16675.1 - 1.5e-05 25.2 0.1 3.2e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO16677.1 - 0.00041 20.5 0.6 0.0019 18.4 0.5 2.2 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KLO16678.1 - 1.4e-05 25.2 0.2 7.1e-05 23.0 0.2 2.1 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO16679.1 - 5.4e-07 29.8 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO16680.1 - 0.0055 16.9 0.5 0.024 14.9 0.5 2.0 1 1 0 1 1 1 1 BTB/POZ domain zf-CCHC_4 PF14392.6 KLO16680.1 - 6 6.7 6.6 1.4 8.7 1.5 2.2 2 0 0 2 2 2 0 Zinc knuckle BTB PF00651.31 KLO16681.1 - 1.2e-05 25.4 0.3 9.8e-05 22.6 0.3 2.1 1 1 0 1 1 1 1 BTB/POZ domain zf-RVT PF13966.6 KLO16684.1 - 0.0024 18.5 0.5 0.0053 17.4 0.5 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 KLO16684.1 - 0.0082 16.3 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 RNase H FtsL PF04999.13 KLO16684.1 - 0.043 13.8 0.1 0.078 13.0 0.1 1.4 1 0 0 1 1 1 0 Cell division protein FtsL BTB PF00651.31 KLO16685.1 - 0.00033 20.9 0.1 0.00097 19.4 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain APH PF01636.23 KLO16686.1 - 2.2e-12 47.4 0.0 6.2e-11 42.7 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KLO16686.1 - 0.00011 21.3 0.0 0.035 13.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) BTB PF00651.31 KLO16687.1 - 9.9e-05 22.5 0.2 0.00015 22.0 0.2 1.5 1 1 0 1 1 1 1 BTB/POZ domain Zn_Tnp_IS1595 PF12760.7 KLO16688.1 - 4.5 7.3 7.2 1.1 9.3 3.1 2.1 2 1 0 2 2 2 0 Transposase zinc-ribbon domain APH PF01636.23 KLO16689.1 - 2.5e-15 57.1 0.0 9.3e-15 55.2 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KLO16689.1 - 2.8e-07 29.8 0.0 0.0034 16.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) BTB PF00651.31 KLO16690.1 - 8.9e-07 29.1 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C3HC4_2 PF13923.6 KLO16691.1 - 6.9e-07 29.0 14.3 1.8e-06 27.7 14.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO16691.1 - 2.8e-06 27.1 13.4 8.9e-06 25.5 13.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO16691.1 - 7.1e-06 25.8 16.8 1.9e-05 24.4 15.6 2.1 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KLO16691.1 - 0.00039 20.2 20.1 0.00039 20.2 20.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO16691.1 - 0.00095 19.5 14.1 0.00095 19.5 14.1 2.3 2 2 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KLO16691.1 - 0.018 15.0 10.9 0.052 13.6 10.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_10 PF16685.5 KLO16691.1 - 0.063 13.4 12.5 0.15 12.2 12.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 KLO16691.1 - 0.15 12.1 23.8 0.13 12.2 19.4 2.7 2 1 1 3 3 3 0 zinc-RING finger domain zf-rbx1 PF12678.7 KLO16691.1 - 2.8 8.3 19.1 1.1 9.6 14.4 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain BTB PF00651.31 KLO16692.1 - 0.0002 21.5 0.3 0.00067 19.9 0.3 1.9 1 1 0 1 1 1 1 BTB/POZ domain Pkinase_Tyr PF07714.17 KLO16694.1 - 2.3e-30 105.7 0.0 2.9e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO16694.1 - 4.2e-26 91.9 0.0 5e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KLO16694.1 - 0.0081 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KLO16694.1 - 0.0092 15.9 0.0 0.016 15.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO16694.1 - 0.02 14.2 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 KLO16695.1 - 1.8e-43 148.7 0.0 3.7e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO16695.1 - 2.8e-38 131.8 0.0 6.7e-38 130.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO16695.1 - 1.8e-05 24.2 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like HEAT PF02985.22 KLO16695.1 - 0.018 15.2 1.9 46 4.7 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat DUF2877 PF11392.8 KLO16695.1 - 0.093 13.5 1.2 0.4 11.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Pkinase_Tyr PF07714.17 KLO16696.1 - 3.6e-38 131.3 0.0 5.9e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO16696.1 - 9e-36 123.6 0.0 1.8e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO16696.1 - 4.8e-07 29.4 0.0 1.2e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.17 KLO16697.1 - 1.1e-09 38.0 0.0 1.8e-09 37.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO16697.1 - 4.6e-07 29.5 0.0 5.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16698.1 - 0.0016 17.7 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO16698.1 - 0.087 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain BTB PF00651.31 KLO16701.1 - 0.00037 20.7 1.7 0.0018 18.5 1.7 2.1 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KLO16702.1 - 1.6e-06 28.4 0.2 9e-06 25.9 0.0 2.2 2 1 0 2 2 2 1 BTB/POZ domain F-box-like PF12937.7 KLO16703.1 - 1.5e-05 24.8 0.0 4.5e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like SUR7 PF06687.12 KLO16704.1 - 2.4e-11 43.7 17.9 1.6e-10 40.9 17.6 2.2 1 1 1 2 2 2 1 SUR7/PalI family Trp_oprn_chp PF09534.10 KLO16704.1 - 0.00049 20.0 1.9 0.00049 20.0 1.9 1.6 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4381 PF14316.6 KLO16704.1 - 0.1 12.8 0.0 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 KLO16704.1 - 4.9 8.1 0.0 4.9 8.1 0.0 3.1 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain F-box-like PF12937.7 KLO16705.1 - 0.0013 18.6 0.0 0.0048 16.8 0.0 2.0 2 0 0 2 2 2 1 F-box-like Histone PF00125.24 KLO16706.1 - 1.5e-19 70.7 0.1 1.9e-19 70.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KLO16706.1 - 3.8e-10 39.3 0.0 7e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KLO16706.1 - 0.0021 18.3 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PS_Dcarbxylase PF02666.15 KLO16707.1 - 5e-44 150.3 0.0 6.5e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase BTB PF00651.31 KLO16708.1 - 7.6e-06 26.1 0.1 3e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 KLO16709.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KLO16712.1 - 0.0022 17.8 0.1 0.0053 16.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like MinE PF03776.14 KLO16712.1 - 0.16 12.0 0.0 0.47 10.5 0.0 1.8 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE F-box-like PF12937.7 KLO16713.1 - 9.6e-05 22.2 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO16714.1 - 2.6e-05 24.0 0.1 8.1e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 F-box-like Cupin_2 PF07883.11 KLO16715.1 - 9.5e-07 28.4 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KLO16715.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Pkinase_Tyr PF07714.17 KLO16717.1 - 9.3e-34 116.9 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO16717.1 - 3.2e-29 102.1 0.0 4.2e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO16717.1 - 0.022 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DDE_3 PF13358.6 KLO16718.1 - 2.6e-07 30.5 0.0 3.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 KLO16718.1 - 0.067 12.2 0.0 0.078 11.9 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain YdjO PF14169.6 KLO16718.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Cold-inducible protein YdjO DDE_3 PF13358.6 KLO16719.1 - 2e-08 34.1 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 KLO16719.1 - 8.3e-05 22.2 0.1 0.00015 21.4 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KLO16719.1 - 8.5e-05 22.7 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 KLO16719.1 - 0.11 11.9 0.0 1 8.8 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Kelch_3 PF13415.6 KLO16720.1 - 0.071 13.4 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain PBP1_TM PF14812.6 KLO16720.1 - 3.2 8.2 21.3 0.059 13.7 10.5 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM76 PF16046.5 KLO16721.1 - 0.00064 19.2 8.2 0.00064 19.2 8.2 2.2 1 1 1 2 2 2 1 FAM76 protein DASH_Dam1 PF08653.10 KLO16721.1 - 0.49 10.2 2.7 4.3 7.2 0.2 3.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 Yae1_N PF09811.9 KLO16721.1 - 1.7 8.4 4.0 1.5 8.5 2.3 1.7 2 0 0 2 2 2 0 Essential protein Yae1, N terminal Fez1 PF06818.15 KLO16721.1 - 3.4 8.1 18.3 11 6.5 17.8 2.1 2 1 0 2 2 2 0 Fez1 CENP-O PF09496.10 KLO16721.1 - 4.7 7.1 7.4 9.5 6.1 7.4 1.4 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component DUF3450 PF11932.8 KLO16721.1 - 8.7 5.6 15.9 2.7 7.2 12.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) GATA PF00320.27 KLO16722.1 - 2.1e-27 94.4 12.8 3.5e-15 55.3 1.9 2.3 2 0 0 2 2 2 2 GATA zinc finger DZR PF12773.7 KLO16722.1 - 0.0017 18.3 7.6 0.12 12.5 7.0 2.7 1 1 1 2 2 2 2 Double zinc ribbon Zn-ribbon_8 PF09723.10 KLO16722.1 - 0.0025 17.9 4.7 0.71 10.0 0.3 2.6 2 0 0 2 2 2 2 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KLO16722.1 - 0.015 15.2 3.3 3 7.9 0.3 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Elf1 PF05129.13 KLO16722.1 - 0.015 15.3 0.4 3.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-RRN7 PF11781.8 KLO16722.1 - 0.017 14.8 0.0 0.017 14.8 0.0 3.7 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5_eIF-2B PF01873.17 KLO16722.1 - 0.018 14.9 5.5 0.72 9.7 0.4 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OTT_1508_deam PF14441.6 KLO16722.1 - 0.046 13.7 2.9 9.6 6.3 0.0 3.0 3 1 0 3 3 3 0 OTT_1508-like deaminase RNA_pol_N PF01194.17 KLO16722.1 - 0.071 13.4 0.5 4.3 7.7 0.0 2.7 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit ArfGap PF01412.18 KLO16722.1 - 0.1 12.7 3.3 1.8 8.7 0.1 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 KLO16722.1 - 0.1 12.1 6.8 0.36 10.4 0.5 2.7 2 1 0 2 2 2 0 TFIIB zinc-binding KCNQ2_u3 PF16642.5 KLO16722.1 - 0.13 13.3 2.6 0.23 12.4 2.6 1.4 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Cytochrom_c3_2 PF14537.6 KLO16722.1 - 0.18 12.3 4.9 0.78 10.2 4.8 2.0 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.6 KLO16722.1 - 0.2 11.7 5.8 0.11 12.5 1.7 2.1 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Auto_anti-p27 PF06677.12 KLO16722.1 - 0.69 10.1 8.2 0.61 10.3 0.7 2.6 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-CHY PF05495.12 KLO16722.1 - 0.74 10.3 4.7 9.3 6.8 0.2 2.3 2 0 0 2 2 2 0 CHY zinc finger OrfB_Zn_ribbon PF07282.11 KLO16722.1 - 0.89 9.5 8.2 3.8 7.5 1.3 2.8 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Cytochrom_CIII PF02085.16 KLO16722.1 - 1.3 9.4 5.4 14 6.1 5.2 2.1 1 1 0 1 1 1 0 Class III cytochrome C family HypA PF01155.19 KLO16722.1 - 1.6 8.8 5.4 1.6e+02 2.4 5.4 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Nudix_N_2 PF14803.6 KLO16722.1 - 2.5 8.1 9.7 3 7.8 1.3 3.5 3 1 0 3 3 3 0 Nudix N-terminal ZF-HD_dimer PF04770.12 KLO16722.1 - 2.6 8.4 8.4 0.51 10.7 0.6 2.8 2 2 0 2 2 2 0 ZF-HD protein dimerisation region zinc_ribbon_5 PF13719.6 KLO16722.1 - 3.4 7.5 5.5 6.4 6.6 0.0 3.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 KLO16722.1 - 9.9 6.3 8.9 0.38 10.8 0.8 2.4 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger HET PF06985.11 KLO16723.1 - 1.8e-06 28.3 0.4 9.2e-05 22.8 0.0 2.5 1 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CENP-B_N PF04218.13 KLO16723.1 - 0.0079 15.8 0.2 0.018 14.6 0.2 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain zf-C2H2 PF00096.26 KLO16724.1 - 1.2e-09 38.1 19.1 0.00032 21.0 0.5 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type HET PF06985.11 KLO16724.1 - 1.3e-07 32.1 0.6 1.2e-05 25.7 0.0 2.5 1 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) zf-C2H2_4 PF13894.6 KLO16724.1 - 5e-06 26.9 17.5 0.32 12.0 0.4 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KLO16724.1 - 0.0004 20.6 5.1 0.032 14.4 0.0 3.2 3 0 0 3 3 3 1 Aberrant zinc-finger FOXP-CC PF16159.5 KLO16724.1 - 0.0015 19.1 3.5 2.9 8.6 0.0 4.3 4 0 0 4 4 4 1 FOXP coiled-coil domain DUF2225 PF09986.9 KLO16724.1 - 0.14 11.8 0.8 0.27 10.9 0.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_8 PF15909.5 KLO16724.1 - 0.21 11.9 2.9 7.3 7.0 0.1 3.7 2 2 2 4 4 4 0 C2H2-type zinc ribbon Na_H_Exchanger PF00999.21 KLO16725.1 - 5.7e-64 216.3 28.6 6.8e-64 216.0 28.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PTS_EIIC_2 PF13303.6 KLO16725.1 - 0.57 9.2 8.7 0.02 13.9 1.8 2.0 2 1 0 2 2 2 0 Phosphotransferase system, EIIC YrhC PF14143.6 KLO16725.1 - 1.2 9.3 2.9 11 6.2 0.6 2.8 2 0 0 2 2 2 0 YrhC-like protein Amino_oxidase PF01593.24 KLO16726.1 - 8.8e-19 68.1 0.0 5.8e-16 58.8 0.0 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KLO16726.1 - 8.2e-12 45.2 0.0 4.4e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KLO16726.1 - 0.00084 19.4 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KLO16726.1 - 0.0027 17.0 0.0 0.24 10.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO16726.1 - 0.0048 16.5 0.0 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KLO16726.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Kinesin PF00225.23 KLO16727.1 - 1.7e-92 309.9 0.0 2.6e-92 309.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KLO16727.1 - 9.1e-20 71.1 0.0 2e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding DUF1340 PF07067.11 KLO16727.1 - 0.056 12.8 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Asp PF00026.23 KLO16728.1 - 9.5e-39 133.6 0.2 1.4e-38 133.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO16728.1 - 1.6e-07 31.8 6.9 5.1e-05 23.6 4.4 3.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KLO16728.1 - 0.021 15.5 2.4 2.9 8.6 0.4 3.5 3 1 0 3 3 3 0 Aspartyl protease SNF2_N PF00176.23 KLO16729.1 - 4.7e-51 173.6 0.1 7.8e-51 172.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO16729.1 - 8.6e-17 61.5 0.0 2.7e-16 59.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KLO16729.1 - 4.9e-06 25.9 2.2 1.2e-05 24.7 0.3 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KLO16729.1 - 2.5e-05 23.6 0.0 4.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Aldo_ket_red PF00248.21 KLO16730.1 - 3.2e-34 118.5 0.0 3.8e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 KLO16731.1 - 4.1e-75 252.6 0.0 4.6e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16731.1 - 2.7e-33 115.4 0.0 3.4e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KLO16731.1 - 0.00012 21.1 0.1 0.0014 17.6 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KLO16731.1 - 0.00039 20.4 0.3 0.0043 17.0 0.1 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO16731.1 - 0.011 15.1 0.1 0.21 10.9 0.0 2.2 1 1 1 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 KLO16731.1 - 0.087 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FKBP_C PF00254.28 KLO16732.1 - 7.9e-32 109.4 0.0 9.1e-32 109.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IGR PF09597.10 KLO16736.1 - 3.8e-22 78.1 0.3 6e-22 77.5 0.3 1.3 1 0 0 1 1 1 1 IGR protein motif SASA PF03629.18 KLO16736.1 - 0.033 13.8 0.0 0.041 13.5 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate esterase, sialic acid-specific acetylesterase Mon1 PF03164.14 KLO16737.1 - 5.6e-110 368.2 0.0 9.1e-110 367.5 0.0 1.3 1 1 0 1 1 1 1 Trafficking protein Mon1 MSP1a PF11670.8 KLO16737.1 - 0.6 9.4 2.0 1 8.6 2.0 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) CMAS PF02353.20 KLO16738.1 - 2e-61 207.7 0.7 2.4e-48 164.8 0.0 2.8 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KLO16738.1 - 1e-08 35.8 0.0 2.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO16738.1 - 2.5e-05 24.8 0.0 5.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO16738.1 - 0.00042 21.0 0.0 0.001 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO16738.1 - 0.00056 19.8 0.0 0.00097 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO16738.1 - 0.00087 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KLO16738.1 - 0.0082 15.2 0.1 0.043 12.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 KLO16738.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain HetR_C PF18460.1 KLO16738.1 - 0.8 9.7 0.0 0.8 9.7 0.0 2.7 3 1 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain Rif1_N PF12231.8 KLO16739.1 - 0.0003 19.9 2.6 0.00037 19.6 1.1 1.9 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal EBP PF05241.12 KLO16740.1 - 1.7e-66 223.1 9.4 2e-66 222.8 9.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein 7tm_1 PF00001.21 KLO16740.1 - 0.024 14.0 0.6 0.036 13.4 0.1 1.6 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) zf-MYND PF01753.18 KLO16741.1 - 5.4e-11 42.4 18.9 9.5e-11 41.6 18.9 1.4 1 0 0 1 1 1 1 MYND finger zf-ribbon_3 PF13248.6 KLO16741.1 - 0.019 14.4 0.8 0.64 9.5 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-C6H2 PF15801.5 KLO16741.1 - 5.2 7.5 12.4 12 6.3 12.4 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MIB_HERC2 PF06701.13 KLO16742.1 - 0.027 14.7 0.5 0.055 13.7 0.1 1.6 2 0 0 2 2 2 0 Mib_herc2 RP853 PF17542.2 KLO16742.1 - 0.14 11.2 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized RP853 HEAT PF02985.22 KLO16746.1 - 0.05 13.9 0.0 0.19 12.0 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat Ifi-6-16 PF06140.13 KLO16747.1 - 1.8e-05 24.5 24.6 2.8e-05 23.9 24.6 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family FSH1 PF03959.13 KLO16747.1 - 0.042 13.5 0.2 0.054 13.1 0.2 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) TarH PF02203.15 KLO16747.1 - 4.6 7.1 5.3 1.1 9.2 1.1 2.0 3 0 0 3 3 3 0 Tar ligand binding domain homologue zf-MYND PF01753.18 KLO16748.1 - 3.5e-09 36.6 13.0 6.2e-09 35.8 13.0 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KLO16748.1 - 0.027 14.8 12.1 0.045 14.1 12.1 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TetR_C_7 PF14246.6 KLO16748.1 - 0.08 13.0 0.0 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain zf-C2H2 PF00096.26 KLO16749.1 - 1.2e-06 28.7 3.0 0.0018 18.7 0.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO16749.1 - 0.00018 22.0 3.7 0.09 13.7 0.0 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KLO16749.1 - 0.035 14.5 9.1 0.21 12.1 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain FOG_N PF15888.5 KLO16749.1 - 0.057 13.8 0.2 0.65 10.4 0.1 2.2 2 0 0 2 2 2 0 Folded gastrulation N-terminus zf-Di19 PF05605.12 KLO16749.1 - 4.8 7.6 5.6 1 9.7 1.1 2.2 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Herpes_capsid PF06112.11 KLO16749.1 - 6.6 6.8 11.1 12 5.9 11.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Linker_histone PF00538.19 KLO16750.1 - 5.6e-07 29.8 0.0 9.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family NmrA PF05368.13 KLO16751.1 - 3.8e-32 111.7 1.8 4.6e-32 111.4 1.8 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO16751.1 - 3.5e-10 40.1 0.6 5.3e-10 39.5 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KLO16751.1 - 0.0085 15.1 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KLO16751.1 - 0.013 15.8 0.1 0.037 14.3 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain TcpA PF05946.12 KLO16751.1 - 0.014 15.5 0.1 0.048 13.8 0.1 1.9 1 1 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA adh_short PF00106.25 KLO16751.1 - 0.046 13.2 1.1 0.17 11.3 0.1 2.4 3 0 0 3 3 3 0 short chain dehydrogenase KR PF08659.10 KLO16751.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 KR domain Zn_clus PF00172.18 KLO16752.1 - 2.4e-07 30.8 8.5 4.6e-07 29.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EMP24_GP25L PF01105.24 KLO16753.1 - 0.04 13.9 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FMO-like PF00743.19 KLO16754.1 - 9.1e-22 77.2 0.0 3.1e-21 75.4 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KLO16754.1 - 1.5e-20 73.7 0.1 3.6e-18 65.9 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KLO16754.1 - 2.6e-15 56.4 1.1 5.4e-10 39.0 0.1 3.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KLO16754.1 - 6.1e-13 48.6 0.0 1.1e-09 37.9 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KLO16754.1 - 6.8e-07 29.4 0.0 0.0052 16.8 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KLO16754.1 - 9.8e-07 29.2 0.2 0.065 13.8 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KLO16754.1 - 5.8e-05 23.1 0.1 0.47 10.4 0.0 3.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding TrkA_N PF02254.18 KLO16754.1 - 5.8e-05 23.3 0.0 0.053 13.8 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain Thi4 PF01946.17 KLO16754.1 - 0.0015 17.8 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 KLO16754.1 - 0.0017 18.8 0.0 0.68 10.4 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KLO16754.1 - 0.0026 16.9 0.3 0.026 13.6 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KLO16754.1 - 0.0058 16.0 0.0 0.61 9.4 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KLO16754.1 - 0.007 15.7 0.1 0.017 14.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KLO16754.1 - 0.0072 15.9 0.0 2.2 7.8 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase ThiP_synth PF10120.9 KLO16754.1 - 0.013 15.1 0.0 0.041 13.5 0.0 1.8 2 0 0 2 2 2 0 Thiamine-phosphate synthase HI0933_like PF03486.14 KLO16754.1 - 0.016 14.0 0.1 0.11 11.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein DUF498 PF04430.14 KLO16754.1 - 0.037 14.1 0.1 0.43 10.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) NAD_binding_8 PF13450.6 KLO16754.1 - 0.049 13.9 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KLO16754.1 - 0.053 12.6 0.1 0.11 11.5 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain DUF4147 PF13660.6 KLO16754.1 - 0.095 12.2 0.0 15 5.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) F420_oxidored PF03807.17 KLO16754.1 - 0.1 13.2 0.0 6.9 7.3 0.0 2.8 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.22 KLO16754.1 - 0.14 11.2 0.1 3.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Abhydrolase_3 PF07859.13 KLO16755.1 - 2.8e-20 73.1 0.1 2.7e-19 69.9 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO16755.1 - 4.4e-11 42.3 0.0 1e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KLO16755.1 - 0.93 10.1 4.9 1.2 9.7 4.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family NmrA PF05368.13 KLO16756.1 - 2.4e-37 128.7 0.2 3.2e-37 128.3 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO16756.1 - 5.3e-12 46.0 0.1 7.8e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KLO16756.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.18 KLO16756.1 - 0.065 13.5 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.24 KLO16756.1 - 0.081 13.4 0.1 0.26 11.7 0.1 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ser_hydrolase PF06821.13 KLO16758.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 KLO16758.1 - 0.0031 18.1 0.0 0.0031 18.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO16758.1 - 0.02 14.2 0.0 0.039 13.2 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Putative_PNPOx PF01243.20 KLO16759.1 - 1e-21 76.9 0.0 1.5e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KLO16759.1 - 3e-20 72.0 3.7 1e-19 70.3 2.8 2.1 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 KLO16759.1 - 0.00025 21.6 0.0 0.00046 20.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase zf-CRD PF17979.1 KLO16760.1 - 2.4e-10 40.8 0.1 2.4e-10 40.8 0.1 2.3 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions zf-C3HC4_2 PF13923.6 KLO16760.1 - 1.9e-06 27.6 11.9 1.9e-06 27.6 11.9 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO16760.1 - 0.00018 21.3 9.6 0.00018 21.3 9.6 3.9 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO16760.1 - 0.00026 21.2 13.0 0.00026 21.2 13.0 4.1 3 1 2 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 KLO16760.1 - 0.0036 17.1 11.9 0.0036 17.1 11.9 4.0 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KLO16760.1 - 0.015 15.1 9.4 0.015 15.1 9.4 2.9 2 1 0 2 2 2 0 zf-RING of BARD1-type protein PPP1R35_C PF15503.6 KLO16760.1 - 0.15 11.8 0.8 0.25 11.2 0.8 1.2 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Kelch_6 PF13964.6 KLO16762.1 - 6.4e-18 64.3 3.0 2.6e-05 24.3 0.4 5.1 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KLO16762.1 - 3.6e-17 61.6 3.4 5.9e-05 22.9 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 KLO16762.1 - 3.6e-14 52.6 3.8 3.2e-07 30.5 0.0 5.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KLO16762.1 - 3.9e-14 52.2 3.0 0.00039 20.3 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KLO16762.1 - 5e-13 48.8 5.2 0.003 17.5 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KLO16762.1 - 1.3e-12 47.1 1.3 0.0035 16.9 0.0 4.3 4 0 0 4 4 4 3 Kelch motif BTB PF00651.31 KLO16762.1 - 0.21 11.8 0.2 4.8 7.4 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain FMO-like PF00743.19 KLO16763.1 - 2.7e-25 88.8 0.2 8.6e-24 83.8 0.2 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KLO16763.1 - 5e-19 68.7 0.0 4.9e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KLO16763.1 - 1.2e-11 44.4 0.1 0.0015 17.8 0.0 3.1 2 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KLO16763.1 - 2.9e-11 43.1 0.4 2.2e-09 36.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KLO16763.1 - 4.6e-05 23.9 1.2 0.037 14.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KLO16763.1 - 0.00021 21.4 0.1 0.11 12.5 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KLO16763.1 - 0.0069 16.6 0.2 0.052 13.8 0.0 2.4 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_8 PF13450.6 KLO16763.1 - 0.0094 16.2 0.0 0.032 14.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KLO16763.1 - 0.015 15.3 0.4 0.56 10.2 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 KLO16763.1 - 0.022 14.3 0.2 7.8 6.0 0.0 3.2 3 1 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KLO16763.1 - 0.052 12.9 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KLO16763.1 - 0.054 13.9 0.0 20 5.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 KLO16763.1 - 0.07 11.8 0.3 0.24 10.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KLO16763.1 - 0.11 11.5 0.0 1.8 7.5 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein FMO-like PF00743.19 KLO16764.1 - 1.1e-24 86.8 0.2 1e-18 67.1 0.0 2.7 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KLO16764.1 - 4e-20 72.3 0.0 2.5e-18 66.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KLO16764.1 - 3e-16 59.5 0.0 3.1e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KLO16764.1 - 3.3e-10 39.7 0.1 1.4e-06 27.8 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KLO16764.1 - 3.8e-06 27.0 0.1 0.0081 16.2 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KLO16764.1 - 1.6e-05 25.0 0.1 0.007 16.4 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KLO16764.1 - 6.5e-05 22.1 0.1 0.00025 20.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KLO16764.1 - 0.00024 20.8 0.7 0.023 14.3 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO16764.1 - 0.00034 19.8 0.3 0.00062 19.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KLO16764.1 - 0.00035 20.0 0.0 0.066 12.6 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KLO16764.1 - 0.00044 20.5 0.0 0.049 13.9 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain GIDA PF01134.22 KLO16764.1 - 0.00052 19.2 0.2 0.025 13.7 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KLO16764.1 - 0.00078 20.0 0.1 0.44 11.1 0.1 3.0 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO16764.1 - 0.0013 17.5 0.4 0.0057 15.4 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KLO16764.1 - 0.0016 18.6 0.0 0.0061 16.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KLO16764.1 - 0.0021 17.4 0.0 0.0092 15.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KLO16764.1 - 0.014 15.8 0.0 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 KLO16764.1 - 0.026 13.8 0.1 0.053 12.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family SnoaL_2 PF12680.7 KLO16764.1 - 0.04 14.6 0.8 0.22 12.2 0.1 2.3 2 0 0 2 2 2 0 SnoaL-like domain FAD_oxidored PF12831.7 KLO16764.1 - 0.043 13.2 0.4 0.067 12.5 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Tachylectin PF14517.6 KLO16764.1 - 0.062 12.8 0.2 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Tachylectin DUF4147 PF13660.6 KLO16764.1 - 0.17 11.4 0.0 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Malic_M PF03949.15 KLO16764.1 - 0.45 9.7 1.3 7.9 5.7 0.1 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Aldolase_II PF00596.21 KLO16765.1 - 8.3e-43 146.5 0.0 1.1e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Pkinase PF00069.25 KLO16769.1 - 7.4e-70 235.3 0.0 1.2e-69 234.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16769.1 - 5.1e-39 134.1 0.0 7.5e-38 130.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO16769.1 - 1.3e-06 28.0 0.0 2.5e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KLO16769.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KLO16769.1 - 0.059 13.0 0.0 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KLO16769.1 - 0.23 10.5 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FolB PF02152.18 KLO16770.1 - 6.5e-36 123.3 0.1 7.4e-18 65.1 0.1 2.1 2 0 0 2 2 2 2 Dihydroneopterin aldolase Glyco_transf_90 PF05686.12 KLO16771.1 - 9.7e-19 67.5 2.1 8.9e-18 64.4 0.1 2.9 3 0 0 3 3 3 1 Glycosyl transferase family 90 Spt5_N PF11942.8 KLO16771.1 - 0.0077 17.2 0.0 0.017 16.1 0.0 1.7 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal Asp PF00026.23 KLO16772.1 - 1.4e-48 165.9 12.5 3.4e-48 164.7 12.5 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO16772.1 - 1.6e-08 35.0 6.7 5.2e-05 23.5 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KLO16772.1 - 0.0014 19.2 3.2 0.37 11.5 0.7 2.8 2 0 0 2 2 2 2 Aspartyl protease Glyco_transf_90 PF05686.12 KLO16773.1 - 4.5e-22 78.5 1.8 1.5e-21 76.8 0.2 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 90 Pkinase PF00069.25 KLO16774.1 - 3.3e-56 190.6 0.0 4.4e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16774.1 - 6.4e-32 110.9 0.0 8.7e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO16774.1 - 4.9e-09 35.9 0.0 6.5e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.11 KLO16774.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KLO16774.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KLO16775.1 - 6e-43 147.1 0.0 8e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16775.1 - 8.1e-42 143.3 0.0 1.1e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO16775.1 - 0.00098 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO16775.1 - 0.012 15.3 0.2 0.024 14.3 0.2 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KLO16775.1 - 0.068 12.5 0.2 0.1 11.9 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO16775.1 - 0.082 12.8 0.0 1.1 9.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RPN13_C PF16550.5 KLO16778.1 - 9.7e-31 106.2 0.1 1.7e-30 105.5 0.1 1.4 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 KLO16778.1 - 2.3e-24 85.8 0.0 3.8e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF2205 PF10224.9 KLO16779.1 - 8.2e-09 35.3 0.4 8.4e-09 35.3 0.4 1.1 1 0 0 1 1 1 1 Short coiled-coil protein TACC_C PF05010.14 KLO16779.1 - 0.0029 17.4 0.7 0.0032 17.3 0.7 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal RPW8 PF05659.11 KLO16779.1 - 0.0077 15.9 0.6 0.0087 15.8 0.6 1.0 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 gpW PF02831.15 KLO16779.1 - 0.057 13.3 0.3 0.1 12.5 0.3 1.5 1 1 0 1 1 1 0 gpW YabA PF06156.13 KLO16779.1 - 0.11 13.2 0.6 0.12 13.0 0.6 1.1 1 0 0 1 1 1 0 Initiation control protein YabA Pet127 PF08634.10 KLO16780.1 - 2e-101 339.1 0.2 4.1e-101 338.0 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial protein Pet127 Peptidase_M3 PF01432.20 KLO16781.1 - 3e-129 432.3 0.0 4e-129 431.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KLO16781.1 - 0.048 13.3 0.3 0.085 12.5 0.3 1.3 1 0 0 1 1 1 0 Peptidase M50B-like HEPN_DZIP3 PF18738.1 KLO16781.1 - 0.1 12.3 0.0 20 4.9 0.0 2.4 2 0 0 2 2 2 0 DZIP3/ hRUL138-like HEPN Usp PF00582.26 KLO16782.1 - 5e-20 72.5 0.1 5e-20 72.5 0.1 2.9 3 0 0 3 3 3 1 Universal stress protein family TPR_10 PF13374.6 KLO16783.1 - 7.8e-48 159.1 26.6 8.3e-07 28.7 0.0 13.4 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_12 PF13424.6 KLO16783.1 - 3.7e-27 94.4 26.8 3.4e-05 24.1 0.6 12.4 6 4 3 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 KLO16783.1 - 7.1e-17 60.1 16.5 0.013 15.6 0.2 10.9 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 KLO16783.1 - 2.4e-13 49.1 19.9 0.44 10.9 0.0 11.5 13 0 0 13 13 12 4 Tetratricopeptide repeat ANAPC5 PF12862.7 KLO16783.1 - 5.8e-11 42.3 30.8 0.19 11.8 0.0 11.8 2 1 7 10 10 10 3 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 KLO16783.1 - 2.1e-06 27.8 11.4 0.016 15.3 0.1 5.6 1 1 6 8 8 8 3 Domain of Unknown Function (DUF3856) TPR_1 PF00515.28 KLO16783.1 - 1.1e-05 25.0 13.0 0.048 13.5 0.1 7.4 9 0 0 9 9 9 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KLO16783.1 - 0.0084 15.5 6.5 0.023 14.1 0.1 4.3 5 0 0 5 5 5 1 SHNi-TPR TPR_17 PF13431.6 KLO16783.1 - 0.011 16.0 10.6 1.3 9.5 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA_16 PF13191.6 KLO16783.1 - 0.019 15.4 3.1 0.16 12.3 0.0 3.5 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KLO16783.1 - 0.041 13.8 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TPR_11 PF13414.6 KLO16783.1 - 0.28 10.9 3.2 2.1 8.1 0.0 4.2 3 1 0 3 3 3 0 TPR repeat TPR_7 PF13176.6 KLO16783.1 - 1.5 9.0 9.2 56 4.1 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat GPI-anchored PF10342.9 KLO16785.1 - 0.00011 22.9 0.0 0.00048 20.8 0.0 1.8 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4611 PF15387.6 KLO16786.1 - 0.0058 16.8 2.9 0.019 15.2 2.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) NOA36 PF06524.12 KLO16786.1 - 0.01 15.2 3.8 0.016 14.5 3.8 1.3 1 0 0 1 1 1 0 NOA36 protein AIM3 PF17096.5 KLO16786.1 - 0.21 12.6 2.2 0.44 11.5 2.2 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 RXT2_N PF08595.11 KLO16786.1 - 0.27 11.2 3.2 0.46 10.5 3.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 KLO16786.1 - 0.54 9.9 3.3 0.96 9.1 3.3 1.4 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 KLO16786.1 - 2.9 5.9 7.3 2.6 6.0 6.2 1.4 2 0 0 2 2 2 0 DNA polymerase phi CENP-B_dimeris PF09026.10 KLO16786.1 - 4.7 7.7 11.4 10 6.6 11.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AAA_23 PF13476.6 KLO16787.1 - 7.4e-15 56.0 64.2 7.4e-15 56.0 64.2 8.1 2 2 2 4 4 2 1 AAA domain AAA_21 PF13304.6 KLO16787.1 - 4.7e-11 43.0 12.5 4.3e-06 26.8 0.6 4.2 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KLO16787.1 - 1e-09 38.2 0.1 1e-09 38.2 0.1 2.6 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KLO16787.1 - 5.4e-09 36.2 60.5 1.4e-08 34.9 8.2 5.6 1 1 1 3 3 2 1 AAA ATPase domain AAA_13 PF13166.6 KLO16787.1 - 2.4e-06 26.5 108.0 0.0044 15.7 0.0 7.2 3 1 2 6 6 4 4 AAA domain SbcCD_C PF13558.6 KLO16787.1 - 5.4e-06 26.6 0.0 2.1e-05 24.7 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Methyltransf_17 PF12692.7 KLO16787.1 - 0.00058 19.9 0.5 0.91 9.5 0.1 3.1 3 0 0 3 3 3 2 S-adenosyl-L-methionine methyltransferase AAA_29 PF13555.6 KLO16787.1 - 0.00065 19.4 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain IFT57 PF10498.9 KLO16787.1 - 0.0014 17.7 94.8 0.012 14.6 10.4 6.9 4 1 2 6 6 6 3 Intra-flagellar transport protein 57 DUF3584 PF12128.8 KLO16787.1 - 0.008 13.8 121.0 0.028 11.9 24.7 6.6 3 1 3 6 6 6 5 Protein of unknown function (DUF3584) Roc PF08477.13 KLO16787.1 - 0.03 14.5 0.0 0.11 12.7 0.0 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KLO16787.1 - 0.22 11.9 0.0 0.22 11.9 0.0 4.8 5 3 0 5 5 3 0 AAA ATPase domain GTP_EFTU PF00009.27 KLO16787.1 - 0.26 10.8 3.8 0.36 10.3 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KLO16787.1 - 0.93 9.8 0.0 0.93 9.8 0.0 3.4 4 0 0 4 4 3 0 AAA domain ECH_1 PF00378.20 KLO16788.1 - 8.8e-81 270.9 0.3 1.2e-80 270.5 0.3 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KLO16788.1 - 5.8e-35 121.4 1.7 3.6e-34 118.8 1.7 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KLO16788.1 - 0.0034 17.4 0.3 0.072 13.0 0.1 2.3 2 0 0 2 2 2 1 Peptidase family S49 AMP-binding PF00501.28 KLO16789.1 - 1.5e-75 254.4 0.0 2.4e-75 253.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme DER1 PF04511.15 KLO16790.1 - 3.4e-47 160.8 8.7 4e-47 160.6 8.7 1.0 1 0 0 1 1 1 1 Der1-like family DUF4083 PF13314.6 KLO16790.1 - 4.5 7.3 4.5 20 5.2 0.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Tam41_Mmp37 PF09139.11 KLO16791.1 - 2e-108 362.7 0.0 2.5e-108 362.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial EB1_binding PF05937.11 KLO16791.1 - 0.11 13.1 10.4 0.19 12.3 10.4 1.3 1 0 0 1 1 1 0 EB-1 Binding Domain adh_short PF00106.25 KLO16792.1 - 1.3e-45 155.3 0.0 1.6e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO16792.1 - 1.9e-37 129.1 0.0 2.3e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO16792.1 - 3.7e-09 36.8 0.0 7.7e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KLO16792.1 - 0.00019 20.9 0.0 0.00024 20.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KLO16792.1 - 0.002 17.3 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KLO16792.1 - 0.0082 15.6 0.1 0.024 14.1 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KLO16792.1 - 0.039 13.5 0.0 0.38 10.3 0.1 2.0 2 0 0 2 2 2 0 NmrA-like family SET PF00856.28 KLO16793.1 - 2.6e-11 44.2 0.0 8.6e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.18 KLO16794.1 - 0.001 19.1 7.6 0.0017 18.4 7.6 1.3 1 0 0 1 1 1 1 MYND finger NDK PF00334.19 KLO16795.1 - 2.6e-17 63.1 0.0 4.3e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Syntaxin PF00804.25 KLO16795.1 - 0.095 12.4 1.5 1.7 8.3 0.0 2.6 3 0 0 3 3 3 0 Syntaxin FXR_C1 PF16096.5 KLO16797.1 - 0.3 11.3 3.5 1.7 8.9 0.2 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 DPBB_1 PF03330.18 KLO16799.1 - 9.2e-07 29.1 0.1 1.6e-06 28.3 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KLO16799.1 - 0.00019 21.3 0.4 0.00028 20.7 0.4 1.3 1 1 0 1 1 1 1 Barwin family Peptidase_M3 PF01432.20 KLO16802.1 - 6.6e-129 431.1 0.0 8.7e-129 430.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KLO16802.1 - 0.047 13.3 0.3 0.084 12.5 0.3 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Alg6_Alg8 PF03155.15 KLO16804.1 - 4.1e-139 464.7 17.6 5.4e-139 464.3 17.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family 4HBT PF03061.22 KLO16805.1 - 1.7e-14 53.9 0.1 2.5e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KLO16805.1 - 0.048 13.8 0.0 0.075 13.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) Pkinase PF00069.25 KLO16806.1 - 1.8e-72 243.9 0.0 3.8e-72 242.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16806.1 - 3.4e-51 174.0 0.0 1.5e-50 171.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO16806.1 - 0.00045 19.1 0.0 0.00087 18.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO16806.1 - 0.0069 15.7 0.0 0.038 13.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RICTOR_N PF14664.6 KLO16806.1 - 0.012 14.6 8.3 0.5 9.3 3.9 2.7 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term DUF5578 PF17741.1 KLO16806.1 - 0.059 12.8 0.1 0.18 11.2 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5578) Ric8 PF10165.9 KLO16806.1 - 0.076 12.0 0.7 7.3 5.5 0.2 2.3 1 1 0 2 2 2 0 Guanine nucleotide exchange factor synembryn RTTN_N PF14726.6 KLO16806.1 - 0.086 13.7 2.0 2.7 8.9 0.0 3.3 2 1 1 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning CDC14 PF08045.11 KLO16806.1 - 0.22 10.6 0.8 0.76 8.8 0.1 2.1 2 0 0 2 2 2 0 Cell division control protein 14, SIN component Kelch_4 PF13418.6 KLO16807.1 - 0.056 13.5 0.2 0.35 10.9 0.1 2.3 2 1 0 2 2 2 0 Galactose oxidase, central domain Phage_int_SAM_4 PF13495.6 KLO16810.1 - 0.01 16.3 0.0 0.028 14.9 0.0 1.8 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 KLO16810.1 - 0.013 15.8 0.1 0.035 14.4 0.1 1.7 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain CENP-F_leu_zip PF10473.9 KLO16811.1 - 0.2 11.7 2.7 0.41 10.7 2.7 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5446 PF17522.2 KLO16811.1 - 0.26 11.5 1.5 0.58 10.4 1.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5446) Pkinase_fungal PF17667.1 KLO16812.1 - 4e-41 141.1 0.0 7e-36 123.9 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase Thioredoxin_3 PF13192.6 KLO16812.1 - 0.15 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain ZapB PF06005.12 KLO16813.1 - 0.0059 17.0 3.5 0.011 16.2 3.5 1.4 1 0 0 1 1 1 1 Cell division protein ZapB GIDA PF01134.22 KLO16813.1 - 0.093 11.8 0.3 0.12 11.4 0.3 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A AAA_lid_9 PF17871.1 KLO16813.1 - 0.13 12.2 5.1 0.26 11.2 4.1 2.1 1 1 1 2 2 2 0 AAA lid domain DUF4890 PF16231.5 KLO16813.1 - 0.34 11.4 5.4 0.42 11.1 4.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4890) UPF0242 PF06785.11 KLO16813.1 - 0.41 10.7 5.2 0.31 11.1 4.2 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CDC48_2 PF02933.17 KLO16814.1 - 5.2e-07 29.4 0.0 6.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Plavaka PF18759.1 KLO16815.1 - 2.4e-70 237.3 0.0 3.5e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase aGPT-Pplase1 PF18723.1 KLO16816.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Phage_integrase PF00589.22 KLO16817.1 - 3.3e-06 27.0 0.0 4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family PhoPQ_related PF10142.9 KLO16818.1 - 0.065 11.9 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein MFS_1 PF07690.16 KLO16819.1 - 8e-39 133.5 40.5 8e-39 133.5 40.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KLO16819.1 - 7e-16 57.8 15.9 1.3e-15 56.9 15.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KLO16819.1 - 7.5e-16 58.0 16.6 1.3e-15 57.2 5.7 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter Acetyltransf_3 PF13302.7 KLO16820.1 - 0.00038 21.1 0.0 0.00053 20.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_S10 PF00338.22 KLO16825.1 - 3.5e-24 84.9 0.0 8.8e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e LamB_YcsF PF03746.16 KLO16829.1 - 7.4e-80 268.1 0.1 8.4e-80 267.9 0.1 1.0 1 0 0 1 1 1 1 LamB/YcsF family Hydrophobin PF01185.18 KLO16830.1 - 4e-24 85.0 11.2 4.5e-24 84.9 11.2 1.0 1 0 0 1 1 1 1 Fungal hydrophobin Diacid_rec PF05651.13 KLO16830.1 - 0.026 14.2 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 Putative sugar diacid recognition Glyco_hydro_79C PF16862.5 KLO16831.1 - 1.4e-11 45.2 0.1 4.4e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Peptidase_M23_N PF18421.1 KLO16831.1 - 0.17 11.8 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M23 N-terminal domain EnY2 PF10163.9 KLO16832.1 - 6.4e-21 74.5 0.1 7.1e-21 74.4 0.1 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Vma12 PF11712.8 KLO16834.1 - 1.5 8.9 4.3 0.73 9.9 1.0 2.0 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Phage_holin_Dp1 PF16938.5 KLO16835.1 - 0.023 14.9 0.1 0.07 13.3 0.1 1.9 1 0 0 1 1 1 0 Putative phage holin Dp-1 Fungus-induced PF10917.8 KLO16836.1 - 0.13 12.6 0.4 0.55 10.6 0.4 2.2 1 0 0 1 1 1 0 Fungus-induced protein F-box PF00646.33 KLO16837.1 - 0.052 13.5 0.0 59 3.7 0.0 3.6 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KLO16837.1 - 0.053 13.4 2.0 0.15 12.0 0.2 2.8 2 1 1 3 3 3 0 F-box-like CPSase_L_D2 PF02786.17 KLO16838.1 - 9e-115 381.5 0.2 8.4e-83 277.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KLO16838.1 - 2.1e-50 169.8 0.0 7.1e-50 168.1 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 KLO16838.1 - 8e-47 159.0 0.0 1.7e-46 157.9 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 KLO16838.1 - 2.1e-43 148.3 0.0 9.1e-43 146.2 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 KLO16838.1 - 6.9e-41 139.4 0.3 1.6e-40 138.3 0.3 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KLO16838.1 - 1.1e-30 106.8 0.1 3.2e-30 105.3 0.0 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KLO16838.1 - 2.5e-18 66.0 0.0 1.7e-17 63.4 0.0 2.6 3 0 0 3 3 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KLO16838.1 - 6.3e-18 65.1 0.1 2.1e-09 37.2 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KLO16838.1 - 2e-15 56.8 0.0 3.4e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KLO16838.1 - 2.5e-10 40.2 0.0 6.5e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KLO16838.1 - 2.7e-05 24.0 0.1 0.0028 17.4 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 KLO16838.1 - 4.8e-05 23.5 0.1 0.088 12.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KLO16838.1 - 0.0042 16.9 0.1 2.1 8.1 0.0 4.1 4 0 0 4 4 4 1 DJ-1/PfpI family zf-MYND PF01753.18 KLO16839.1 - 3e-11 43.2 12.9 4.6e-11 42.6 12.9 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO16839.1 - 0.0046 17.0 7.1 0.008 16.3 7.1 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-NADH-PPase PF09297.11 KLO16839.1 - 0.28 10.9 5.2 0.47 10.2 0.2 2.4 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-HIT PF04438.16 KLO16839.1 - 0.77 9.7 7.6 1.3 8.9 7.6 1.3 1 0 0 1 1 1 0 HIT zinc finger p450 PF00067.22 KLO16841.1 - 1.4e-70 238.4 0.1 3.4e-70 237.1 0.1 1.5 1 1 0 1 1 1 1 Cytochrome P450 GyrB_insert PF18053.1 KLO16841.1 - 0.021 14.7 0.0 0.063 13.2 0.0 1.7 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain Tubulin PF00091.25 KLO16842.1 - 6.6e-69 232.1 0.0 1.7e-68 230.7 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KLO16842.1 - 5.5e-42 142.9 0.2 9.4e-42 142.2 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KLO16842.1 - 3.8e-06 27.2 0.0 1.1e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KLO16842.1 - 0.00046 19.5 0.0 0.017 14.3 0.0 2.2 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KLO16842.1 - 0.026 14.2 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain TrmK PF04816.12 KLO16842.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase dsrm PF00035.26 KLO16843.1 - 6.5e-09 36.4 0.0 6e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif Arm-DNA-bind_3 PF13356.6 KLO16843.1 - 0.078 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Arm DNA-binding domain DivIC PF04977.15 KLO16843.1 - 0.17 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Septum formation initiator Pkinase_Tyr PF07714.17 KLO16844.1 - 4.2e-32 111.5 0.0 5.5e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO16844.1 - 1e-29 103.8 0.0 1.4e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO16844.1 - 0.0097 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO16844.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 KLO16844.1 - 0.16 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.25 KLO16845.1 - 1.7e-33 116.1 0.0 2.9e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16845.1 - 3.2e-33 115.1 0.0 5e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO16845.1 - 0.0092 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KLO16845.1 - 0.032 13.3 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KLO16845.1 - 0.035 13.4 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KLO16845.1 - 0.099 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase WaaY PF06176.11 KLO16845.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH_6_hur PF04655.14 KLO16845.1 - 0.16 11.3 0.0 0.43 9.9 0.0 1.6 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase adh_short PF00106.25 KLO16846.1 - 8.3e-45 152.6 0.0 1.1e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO16846.1 - 8.6e-45 153.1 0.1 1e-44 152.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO16846.1 - 1.4e-10 41.4 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO16846.1 - 0.0012 18.4 0.1 0.007 15.9 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KLO16846.1 - 0.035 13.5 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KLO16846.1 - 0.041 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KLO16846.1 - 0.08 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain zf-H2C2_2 PF13465.6 KLO16847.1 - 3.9e-09 36.5 3.7 4.3e-07 30.1 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KLO16847.1 - 2.9e-08 33.7 7.2 2.6e-06 27.5 0.3 3.9 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO16847.1 - 5.7e-06 26.7 6.1 0.0031 18.2 0.3 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 KLO16847.1 - 3.4e-05 24.4 9.5 0.048 14.3 1.8 3.3 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-Di19 PF05605.12 KLO16847.1 - 0.00033 20.9 1.8 0.019 15.2 0.4 2.4 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KLO16847.1 - 0.082 12.9 1.6 0.18 11.8 0.0 2.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KLO16847.1 - 0.19 12.1 0.0 0.51 10.7 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KLO16847.1 - 0.22 12.0 1.5 1.4 9.4 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KLO16847.1 - 0.25 11.5 0.1 5.9 7.0 0.1 2.2 1 1 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 KLO16847.1 - 0.62 9.9 3.2 4.4 7.1 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain TPR_14 PF13428.6 KLO16848.1 - 1.5e-10 40.9 19.0 0.4 11.6 0.5 8.6 6 3 3 9 9 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KLO16848.1 - 2.1e-09 36.8 17.5 0.27 11.4 0.1 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KLO16848.1 - 3.7e-09 36.0 1.0 0.21 11.5 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KLO16848.1 - 1.9e-08 33.9 0.7 0.099 12.3 0.0 5.2 4 1 1 5 5 5 2 TPR repeat TPR_8 PF13181.6 KLO16848.1 - 1.1e-07 31.5 1.1 0.11 12.8 0.0 5.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KLO16848.1 - 1.1e-07 32.2 11.6 0.77 10.3 1.2 6.6 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KLO16848.1 - 1e-06 29.2 11.1 2.4 8.9 0.1 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KLO16848.1 - 6.6e-06 26.2 0.2 0.55 10.7 0.0 5.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KLO16848.1 - 0.012 15.9 13.1 0.54 10.6 0.2 6.4 5 2 1 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 KLO16848.1 - 0.05 13.7 0.1 0.05 13.7 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO16848.1 - 0.062 13.5 11.0 1.2 9.4 0.7 5.2 7 0 0 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 PRIMA1 PF16101.5 KLO16848.1 - 0.35 10.9 2.3 1 9.4 2.3 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TPR_4 PF07721.14 KLO16848.1 - 0.38 11.5 12.9 2 9.3 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat SprA-related PF12118.8 KLO16848.1 - 0.91 8.6 9.7 1.7 7.7 9.7 1.3 1 0 0 1 1 1 0 SprA-related family TPR_7 PF13176.6 KLO16848.1 - 0.97 9.6 4.3 53 4.2 0.0 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat Alginate_lyase PF05426.12 KLO16850.1 - 1.7e-52 178.7 0.5 2.2e-52 178.3 0.5 1.1 1 0 0 1 1 1 1 Alginate lyase TAFII28 PF04719.14 KLO16851.1 - 4.8e-34 116.3 0.1 6e-34 116.0 0.1 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 KLO16851.1 - 0.0056 16.9 0.0 0.0083 16.4 0.0 1.3 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-X PF09415.10 KLO16851.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Ly49 PF08391.10 KLO16853.1 - 0.12 12.7 1.2 0.22 11.9 0.4 1.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF3433 PF11915.8 KLO16854.1 - 1.1e-18 67.5 2.1 1.1e-18 67.5 2.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) Hce2 PF14856.6 KLO16855.1 - 0.0087 16.3 1.6 0.016 15.5 1.6 1.4 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor FmrO PF07091.11 KLO16856.1 - 0.037 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Borrelia_lipo_1 PF05714.11 KLO16857.1 - 0.017 14.9 0.6 0.034 13.9 0.6 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein DNA_pol_phi PF04931.13 KLO16857.1 - 3.5 5.6 7.6 5.3 5.0 7.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi O-FucT PF10250.9 KLO16858.1 - 3.3e-11 43.5 0.0 5.5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase zf-CSL PF05207.13 KLO16859.1 - 1.8e-22 78.8 0.9 5.2e-22 77.3 0.9 1.8 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KLO16859.1 - 0.0035 17.4 0.8 0.0064 16.6 0.8 1.4 1 0 0 1 1 1 1 Zinc ribbon domain RNA_pol_3_Rpc31 PF11705.8 KLO16859.1 - 0.023 14.9 11.3 0.027 14.7 11.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 KLO16859.1 - 0.096 12.1 10.8 0.086 12.3 10.8 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 KLO16859.1 - 0.11 11.9 10.7 0.13 11.6 10.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 KLO16859.1 - 0.13 11.6 9.6 0.14 11.5 9.6 1.1 1 0 0 1 1 1 0 BUD22 Terminase_GpA PF05876.12 KLO16859.1 - 0.13 10.8 1.0 0.22 10.0 1.0 1.4 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) CDC45 PF02724.14 KLO16859.1 - 0.32 9.2 9.9 0.35 9.1 9.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 KLO16859.1 - 0.47 10.3 11.3 0.56 10.1 11.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 KLO16859.1 - 0.5 8.5 14.6 0.51 8.5 14.6 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KLO16859.1 - 0.53 9.8 10.8 0.6 9.7 10.8 1.1 1 0 0 1 1 1 0 PPP4R2 Paf1 PF03985.13 KLO16859.1 - 0.93 8.4 10.7 1.4 7.8 10.7 1.2 1 0 0 1 1 1 0 Paf1 NPR3 PF03666.13 KLO16859.1 - 2.9 6.6 4.8 4 6.1 4.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 KLO16859.1 - 7.3 4.6 26.6 8.9 4.3 26.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 KLO16859.1 - 8 4.9 14.0 9.1 4.7 14.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF21 PF01595.20 KLO16860.1 - 5.5e-28 97.8 0.2 8.5e-28 97.2 0.2 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain Proteasome PF00227.26 KLO16861.1 - 9e-28 97.1 0.0 1.1e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit p450 PF00067.22 KLO16864.1 - 1.6e-52 178.8 1.2 1.4e-51 175.7 1.2 1.9 1 1 0 1 1 1 1 Cytochrome P450 Kdo PF06293.14 KLO16865.1 - 2e-11 43.7 0.0 1.7e-10 40.6 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO16865.1 - 7.2e-07 29.4 0.0 4.1e-06 26.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KLO16865.1 - 0.00021 20.7 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KLO16865.1 - 0.00025 20.7 0.0 0.089 12.4 0.0 2.2 1 1 1 2 2 2 2 RIO1 family EcKinase PF02958.20 KLO16865.1 - 0.00035 20.0 0.0 0.00087 18.7 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.17 KLO16865.1 - 0.047 13.0 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase UPF0172 PF03665.13 KLO16866.1 - 1.6e-47 162.1 0.0 1.8e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 KLO16866.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Hce2 PF14856.6 KLO16867.1 - 0.0056 16.9 3.4 0.012 15.9 3.4 1.5 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor GFO_IDH_MocA PF01408.22 KLO16868.1 - 5.2e-20 72.5 0.0 8.5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.16 KLO16868.1 - 0.014 16.1 0.0 0.054 14.2 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.24 KLO16868.1 - 0.067 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain LBR_tudor PF09465.10 KLO16868.1 - 0.12 12.2 0.5 0.95 9.3 0.0 2.3 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Carn_acyltransf PF00755.20 KLO16869.1 - 4.9e-205 682.6 0.0 5.7e-205 682.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ASXH PF13919.6 KLO16870.1 - 1.5e-22 80.1 1.8 7.9e-22 77.8 1.8 2.1 1 1 0 1 1 1 1 Asx homology domain Presenilin PF01080.17 KLO16870.1 - 0.91 8.2 9.3 0.68 8.6 0.3 2.1 2 0 0 2 2 2 0 Presenilin Redoxin PF08534.10 KLO16871.1 - 1.4e-27 96.2 0.1 1.7e-27 95.9 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KLO16871.1 - 5.5e-10 39.2 0.0 6.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KLO16871.1 - 0.031 14.6 0.0 0.047 14.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like RusA PF05866.11 KLO16872.1 - 0.031 14.8 0.2 0.046 14.3 0.2 1.2 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA zf-C2H2_aberr PF17017.5 KLO16873.1 - 0.42 10.8 13.0 0.74 9.9 0.3 3.0 4 0 0 4 4 4 0 Aberrant zinc-finger GFO_IDH_MocA PF01408.22 KLO16878.1 - 1.2e-18 68.0 0.0 1.9e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.16 KLO16878.1 - 0.0039 17.9 0.0 0.0092 16.7 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase GFO_IDH_MocA_C PF02894.17 KLO16878.1 - 0.025 14.6 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain NIBRIN_BRCT_II PF16508.5 KLO16880.1 - 0.0016 18.8 0.0 0.0036 17.6 0.0 1.7 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KLO16880.1 - 0.0023 18.3 0.0 0.0051 17.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 KLO16880.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain CYYR1 PF10873.8 KLO16880.1 - 6.2 7.3 5.6 10 6.6 0.1 2.6 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 SKG6 PF08693.10 KLO16881.1 - 1.1e-05 24.7 0.4 1.1e-05 24.7 0.4 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KLO16881.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Lactamase_B_2 PF12706.7 KLO16882.1 - 6.6e-34 117.2 0.0 1e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KLO16882.1 - 2.8e-12 46.9 0.0 1.5e-11 44.4 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KLO16882.1 - 0.0063 16.5 0.2 0.054 13.5 0.1 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily zf-4CXXC_R1 PF10497.9 KLO16884.1 - 1.1e-10 41.5 13.7 2.4e-10 40.5 13.7 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 MMR_HSR1 PF01926.23 KLO16885.1 - 3.4e-18 65.8 0.0 1.2e-14 54.4 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO16885.1 - 7.6e-08 32.4 0.1 1.2e-06 28.5 0.1 2.3 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KLO16885.1 - 1.1e-06 28.3 0.0 4.9e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KLO16885.1 - 9.6e-05 22.0 0.0 0.01 15.4 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KLO16885.1 - 0.001 19.1 0.3 0.29 11.2 0.1 2.7 2 1 1 3 3 3 1 Dynamin family AAA_16 PF13191.6 KLO16885.1 - 0.0017 18.8 0.5 0.17 12.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 KLO16885.1 - 0.013 15.7 0.1 4 7.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KLO16885.1 - 0.036 13.4 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 AIG1 family MeaB PF03308.16 KLO16885.1 - 0.071 12.1 0.1 0.17 10.8 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KLO16885.1 - 0.076 12.6 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KLO16885.1 - 0.14 12.7 0.1 0.44 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Glyco_hydro_16 PF00722.21 KLO16886.1 - 6.9e-16 58.2 0.1 2.1e-15 56.6 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 SPR1 PF15356.6 KLO16886.1 - 0.17 12.4 2.0 15 6.1 0.1 2.6 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 Glyco_trans_2_3 PF13632.6 KLO16887.1 - 3.3e-56 190.4 0.3 3.3e-56 190.4 0.3 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KLO16887.1 - 3.8e-06 27.0 0.2 8.6e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KLO16887.1 - 0.0062 16.4 0.0 0.048 13.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KLO16887.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 F-box-like PF12937.7 KLO16888.1 - 4.7e-06 26.4 0.0 1.9e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 F-box-like MCU PF04678.13 KLO16889.1 - 2.5e-27 96.1 0.5 3.5e-27 95.6 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial calcium uniporter DUF4268 PF14088.6 KLO16889.1 - 0.078 12.9 2.1 0.14 12.0 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) p450 PF00067.22 KLO16890.1 - 4.5e-07 29.0 0.0 5.1e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Colicin_V PF02674.16 KLO16890.1 - 0.08 12.9 0.0 0.097 12.6 0.0 1.1 1 0 0 1 1 1 0 Colicin V production protein p450 PF00067.22 KLO16891.1 - 1.9e-47 162.1 0.0 8.1e-47 160.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KLO16893.1 - 9.9e-10 38.4 6.1 1.2e-09 38.1 6.1 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bax1-I PF01027.20 KLO16894.1 - 1.5e-43 149.1 19.0 1.7e-43 148.9 19.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MDM31_MDM32 PF08118.11 KLO16895.1 - 4.2e-205 682.4 0.0 4.8e-205 682.2 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins CMAS PF02353.20 KLO16896.1 - 2.1e-36 125.6 0.1 2.7e-36 125.3 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KLO16896.1 - 5e-15 55.6 0.0 9.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO16896.1 - 1.5e-13 51.3 0.0 3.4e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO16896.1 - 3.6e-11 43.5 0.0 1e-10 42.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO16896.1 - 8.9e-11 41.9 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO16896.1 - 2.3e-09 37.9 0.0 6.5e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO16896.1 - 1.3e-08 34.6 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KLO16896.1 - 7.4e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 KLO16896.1 - 4.4e-05 23.2 0.0 0.00018 21.1 0.0 2.0 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 KLO16896.1 - 0.0007 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 KLO16896.1 - 0.001 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.15 KLO16896.1 - 0.0012 18.2 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G DUF938 PF06080.12 KLO16896.1 - 0.0083 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.20 KLO16896.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KLO16896.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KLO16896.1 - 0.058 12.4 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase FtsJ PF01728.19 KLO16896.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MmgE_PrpD PF03972.14 KLO16897.1 - 3.9e-158 526.6 0.0 4.4e-158 526.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family GFA PF04828.14 KLO16898.1 - 1.5e-22 79.8 0.3 1.9e-22 79.4 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme GFA PF04828.14 KLO16899.1 - 4.2e-19 68.7 2.0 5.5e-19 68.3 2.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NinF PF05810.12 KLO16899.1 - 0.05 13.5 0.0 0.05 13.5 0.0 1.8 2 0 0 2 2 2 0 NinF protein Metallothio_2 PF01439.18 KLO16900.1 - 4.4 8.3 9.0 1.2 10.1 5.5 1.9 2 0 0 2 2 2 0 Metallothionein Slu7 PF11708.8 KLO16901.1 - 7e-108 360.4 11.2 7e-108 360.4 11.2 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor DUF1771 PF08590.10 KLO16902.1 - 0.00077 19.8 5.6 0.0012 19.1 5.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) RNase_H2-Ydr279 PF09468.10 KLO16903.1 - 4.8e-18 65.8 0.1 9.4e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KLO16903.1 - 5.8e-10 39.3 0.0 1.7e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain IF-2B PF01008.17 KLO16904.1 - 1.5e-63 214.7 0.0 1.7e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family AAA_28 PF13521.6 KLO16904.1 - 0.025 14.8 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3421 PF11901.8 KLO16905.1 - 2.1e-05 24.5 0.0 5e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3421) DUF3421 PF11901.8 KLO16906.1 - 8.7e-06 25.7 0.0 6.3e-05 22.9 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3421) CMAS PF02353.20 KLO16907.1 - 6.6e-25 87.9 0.1 1.2e-24 87.0 0.1 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KLO16907.1 - 3.9e-09 37.1 0.0 8.3e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO16907.1 - 1.2e-07 31.7 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO16907.1 - 7.8e-07 28.8 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KLO16907.1 - 2.8e-06 27.2 0.0 9.3e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KLO16907.1 - 3.6e-06 26.6 0.0 6.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 KLO16907.1 - 3.7e-06 27.5 0.0 8.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO16907.1 - 8.5e-05 23.2 0.0 0.00033 21.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KLO16907.1 - 0.00082 18.5 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TehB PF03848.14 KLO16907.1 - 0.026 13.9 0.0 0.059 12.8 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KLO16907.1 - 0.031 14.3 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KLO16907.1 - 0.033 14.0 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GidB PF02527.15 KLO16907.1 - 0.04 13.2 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G FtsJ PF01728.19 KLO16907.1 - 0.042 13.9 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KLO16907.1 - 0.048 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KLO16907.1 - 0.082 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 KLO16907.1 - 0.098 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 KLO16907.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain LON_substr_bdg PF02190.16 KLO16907.1 - 0.15 12.0 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain F-box-like PF12937.7 KLO16910.1 - 3.9e-06 26.7 0.2 1.7e-05 24.6 0.2 2.2 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO16911.1 - 1.6e-05 24.7 0.3 4.8e-05 23.2 0.3 1.9 1 0 0 1 1 1 1 F-box-like Spidroin_N PF16763.5 KLO16911.1 - 0.19 11.8 0.1 0.59 10.2 0.1 1.9 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term F-box-like PF12937.7 KLO16912.1 - 1.3e-07 31.4 0.9 6.6e-07 29.1 0.1 2.7 4 0 0 4 4 4 1 F-box-like F-box-like_2 PF13013.6 KLO16912.1 - 0.0085 16.0 0.3 0.072 13.1 0.0 2.4 2 0 0 2 2 2 1 F-box-like domain LRR_4 PF12799.7 KLO16912.1 - 4.2 7.9 5.8 14 6.3 0.1 4.3 4 1 2 6 6 5 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 KLO16914.1 - 2.2e-34 119.0 0.0 3.1e-21 75.9 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16914.1 - 2.5e-17 63.0 0.0 5.6e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 KLO16915.1 - 8.4e-06 25.6 0.9 2e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 F-box-like SUB1_ProdP9 PF18213.1 KLO16915.1 - 0.013 15.4 0.0 0.6 10.0 0.0 2.8 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 F-box PF00646.33 KLO16915.1 - 0.11 12.4 1.1 7.8 6.5 0.2 3.0 2 0 0 2 2 2 0 F-box domain p450 PF00067.22 KLO16916.1 - 1.5e-68 231.7 0.0 1.8e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AATase PF07247.12 KLO16917.1 - 3.8e-24 85.1 0.0 1.9e-23 82.8 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 KLO16917.1 - 0.0046 15.7 0.0 0.75 8.4 0.0 2.1 2 0 0 2 2 2 2 Condensation domain U3_assoc_6 PF08640.11 KLO16918.1 - 8.3e-30 102.7 0.1 1.7e-28 98.5 0.2 2.6 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KLO16918.1 - 0.00012 22.6 0.3 2 9.4 0.1 4.3 1 1 2 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KLO16918.1 - 0.00021 20.5 2.0 0.0022 17.2 0.0 3.2 3 1 0 3 3 3 1 NRDE-2, necessary for RNA interference XkdW PF09636.10 KLO16918.1 - 0.088 12.9 0.2 3.6 7.7 0.1 2.9 2 0 0 2 2 2 0 XkdW protein DUF1572 PF07609.11 KLO16918.1 - 0.13 12.1 0.2 0.27 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) O-FucT PF10250.9 KLO16919.1 - 2.4e-05 24.2 0.0 0.0023 17.7 0.0 2.1 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Glyco_hyd_101C PF17451.2 KLO16919.1 - 0.16 12.3 0.2 0.31 11.3 0.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain Aldedh PF00171.22 KLO16920.1 - 6.9e-79 265.5 0.0 8.6e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ACT_7 PF13840.6 KLO16920.1 - 0.0058 16.4 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 ACT domain DUF1455 PF07306.11 KLO16921.1 - 0.023 14.7 1.0 0.056 13.4 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) Cwf_Cwc_15 PF04889.12 KLO16923.1 - 0.13 12.0 5.5 0.18 11.5 5.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 KLO16923.1 - 0.15 11.7 6.6 0.23 11.0 6.6 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KLO16923.1 - 1.7 6.8 8.7 2.2 6.4 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 KLO16923.1 - 3.9 6.5 9.1 6 5.9 9.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein MFS_1 PF07690.16 KLO16924.1 - 1.7e-17 63.4 32.9 1.7e-17 63.4 32.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM100 PF16311.5 KLO16924.1 - 0.12 12.0 0.0 16 5.1 0.0 2.9 2 0 0 2 2 2 0 Transmembrane protein 100 Got1 PF04178.12 KLO16925.1 - 7e-19 68.3 13.8 8.8e-19 68.0 13.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Aldo_ket_red PF00248.21 KLO16931.1 - 8e-53 179.5 0.0 9e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KLO16932.1 - 1.3e-33 116.5 0.0 1.9e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KLO16933.1 - 1.9e-50 171.8 0.0 2.1e-50 171.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_108 PF05838.12 KLO16933.1 - 0.064 13.7 1.9 5.8 7.5 0.0 3.0 2 1 1 3 3 3 0 Glycosyl hydrolase 108 HSP70 PF00012.20 KLO16941.1 - 2.8e-153 511.3 0.1 2.8e-153 511.3 0.1 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KLO16941.1 - 7.9e-10 38.1 0.3 2.4e-09 36.5 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 KLO16941.1 - 0.2 11.7 1.1 0.98 9.5 0.0 2.6 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain zinc_ribbon_16 PF17034.5 KLO16942.1 - 1.5e-16 60.8 7.7 4.5e-16 59.2 7.7 1.9 1 0 0 1 1 1 1 Zinc-ribbon like family ANAPC4_WD40 PF12894.7 KLO16942.1 - 0.012 15.9 0.0 0.32 11.3 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Zn_ribbon_17 PF17120.5 KLO16942.1 - 2.9 7.6 14.2 0.014 15.0 3.8 2.4 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 KLO16943.1 - 1.8e-15 56.9 28.5 3.2e-09 36.9 16.6 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KLO16943.1 - 9.6e-05 22.2 8.3 9.6e-05 22.2 8.3 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO16943.1 - 0.0026 17.5 8.3 0.0026 17.5 8.3 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.6 KLO16943.1 - 0.071 12.9 0.1 3 7.7 0.0 2.8 2 0 0 2 2 2 0 UBA-like domain zf-RING_4 PF14570.6 KLO16943.1 - 1.2 9.0 21.6 3.7 7.4 7.4 3.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain UBA2_C PF16195.5 KLO16943.1 - 4.5 8.0 8.5 0.85 10.3 1.9 2.6 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus tRNA-synt_2 PF00152.20 KLO16944.1 - 7.7e-77 258.4 0.0 1e-76 258.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KLO16944.1 - 2.6e-11 43.3 0.1 1.5e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KLO16944.1 - 3.4e-08 33.3 0.0 0.00037 20.1 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Glyco_tranf_2_3 PF13641.6 KLO16945.1 - 5.1e-30 105.1 0.0 7.5e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KLO16945.1 - 1.5e-11 44.4 0.0 2.3e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KLO16945.1 - 6.1e-07 29.1 0.1 4e-06 26.4 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KLO16945.1 - 0.001 19.0 8.0 0.0025 17.8 8.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Use1 PF09753.9 KLO16946.1 - 6.7e-20 71.9 0.0 1.3e-19 70.9 0.0 1.6 2 0 0 2 2 2 1 Membrane fusion protein Use1 DASH_Dad4 PF08650.10 KLO16948.1 - 7.7e-27 93.1 0.2 8.2e-27 93.0 0.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DUF3683 PF12447.8 KLO16948.1 - 0.0037 17.4 0.7 0.0045 17.1 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3683) DASH_Dad1 PF08649.10 KLO16948.1 - 0.007 16.5 0.1 0.0085 16.3 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 RPW8 PF05659.11 KLO16948.1 - 0.017 14.8 0.1 0.02 14.6 0.1 1.0 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 OSTMP1 PF09777.9 KLO16948.1 - 0.037 13.4 0.0 0.04 13.3 0.0 1.0 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF3837 PF12939.7 KLO16948.1 - 0.093 13.1 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) GATase_5 PF13507.6 KLO16949.1 - 3e-100 334.6 0.0 4.5e-100 334.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KLO16949.1 - 1.2e-41 142.4 0.0 7.9e-28 97.6 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KLO16949.1 - 4.5e-31 107.2 0.0 7.8e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KLO16949.1 - 7.8e-22 77.6 0.0 1.7e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 KLO16949.1 - 0.048 14.3 0.2 0.69 10.6 0.0 2.8 3 0 0 3 3 3 0 AIR synthase related protein, N-terminal domain Chitin_synth_1 PF01644.17 KLO16951.1 - 2.8e-76 255.0 0.0 4.2e-76 254.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KLO16951.1 - 1.1e-26 92.6 0.6 3.8e-26 90.8 0.1 2.3 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KLO16951.1 - 4.8e-26 91.5 0.9 4.6e-20 71.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KLO16951.1 - 1.2e-09 38.4 3.6 7.5e-09 35.8 3.6 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Oxidored_q4 PF00507.19 KLO16951.1 - 4.5 7.5 11.6 2.2 8.5 3.5 2.6 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Pkinase_Tyr PF07714.17 KLO16952.1 - 8.7e-34 117.0 0.0 1.1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO16952.1 - 4.3e-31 108.3 0.0 5.4e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain UDPGT PF00201.18 KLO16953.1 - 2.9e-17 62.7 0.1 4.4e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase BAG PF02179.16 KLO16954.1 - 1.1e-14 54.7 0.0 1.6e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KLO16954.1 - 1.6e-09 37.4 0.1 3.8e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 KLO16954.1 - 0.0022 18.4 0.0 0.014 15.8 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain DUF4810 PF16068.5 KLO16954.1 - 0.12 13.0 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) Pkinase PF00069.25 KLO16955.1 - 7.4e-57 192.7 0.0 9.1e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO16955.1 - 1.1e-37 129.7 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO16955.1 - 5.3e-06 25.9 0.0 8.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO16955.1 - 0.0074 15.1 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KLO16955.1 - 0.017 14.1 0.0 0.039 12.9 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KLO16955.1 - 0.028 14.3 0.0 0.12 12.3 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KLO16955.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Exo_endo_phos PF03372.23 KLO16956.1 - 1.2e-06 28.3 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Asparaginase_2 PF01112.18 KLO16957.1 - 3.5e-59 200.3 1.6 4.9e-59 199.9 1.6 1.1 1 0 0 1 1 1 1 Asparaginase tRNA-synt_1 PF00133.22 KLO16958.1 - 5.9e-205 682.0 0.1 1.3e-204 680.9 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KLO16958.1 - 2.5e-26 92.5 0.5 8.2e-26 90.8 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KLO16958.1 - 2.2e-14 53.0 0.6 0.00026 19.8 0.0 4.0 4 0 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KLO16958.1 - 0.00079 18.9 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain EFG_C PF00679.24 KLO16958.1 - 0.15 12.1 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 Elongation factor G C-terminus FAD_binding_3 PF01494.19 KLO16959.1 - 3.4e-21 75.9 0.0 1.1e-20 74.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KLO16959.1 - 0.0022 17.1 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 KLO16959.1 - 0.004 17.3 0.1 0.013 15.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO16959.1 - 0.0088 15.3 0.4 0.2 10.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KLO16959.1 - 0.009 14.9 1.0 0.054 12.3 0.1 2.4 3 0 0 3 3 3 1 Tryptophan halogenase DAO PF01266.24 KLO16959.1 - 0.04 13.5 0.1 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase tRNA-synt_1 PF00133.22 KLO16960.1 - 1.1e-214 714.1 0.0 2.1e-214 713.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KLO16960.1 - 7.6e-24 84.4 0.2 3.1e-23 82.4 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KLO16960.1 - 1.3e-15 57.1 1.1 0.00029 19.7 0.1 4.2 3 1 1 4 4 4 4 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KLO16960.1 - 0.00099 18.5 0.0 0.0042 16.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain RBFA PF02033.18 KLO16960.1 - 0.049 14.1 0.1 2.3 8.7 0.0 2.9 3 0 0 3 3 3 0 Ribosome-binding factor A DEAD PF00270.29 KLO16961.1 - 3.8e-38 131.0 0.0 7.7e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KLO16961.1 - 7.3e-18 64.5 0.4 1.3e-17 63.7 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KLO16961.1 - 5e-17 62.2 0.0 5.1e-16 59.0 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO16961.1 - 0.00011 22.2 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EXS PF03124.14 KLO16962.1 - 1.6e-97 326.8 9.7 1.9e-97 326.6 9.7 1.1 1 0 0 1 1 1 1 EXS family Anticodon_1 PF08264.13 KLO16962.1 - 0.082 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA zf-C2H2_jaz PF12171.8 KLO16963.1 - 5.1e-05 23.4 0.0 9.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KLO16963.1 - 0.00012 22.3 0.1 0.00024 21.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 KLO16963.1 - 0.0022 18.0 0.1 0.0043 17.1 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger SNRNP27 PF08648.12 KLO16963.1 - 0.0036 17.3 0.9 0.0036 17.3 0.9 2.4 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins Orbi_VP6 PF01516.16 KLO16963.1 - 0.0041 16.7 3.2 0.0041 16.7 3.2 1.8 2 0 0 2 2 2 1 Orbivirus helicase VP6 DUF4660 PF15559.6 KLO16963.1 - 0.012 15.9 1.7 0.012 15.9 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) zf-C2H2 PF00096.26 KLO16963.1 - 0.28 11.7 1.6 0.46 11.0 0.7 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Atg14 PF10186.9 KLO16963.1 - 5.8 5.9 17.9 1.1 8.3 1.7 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2462 PF09495.10 KLO16963.1 - 6.9 7.5 18.3 0.39 11.5 6.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) Pro_isomerase PF00160.21 KLO16964.1 - 6e-48 163.1 0.2 8.9e-48 162.5 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DPBB_1 PF03330.18 KLO16965.1 - 8.9e-05 22.7 0.1 0.00016 21.9 0.1 1.5 1 0 0 1 1 1 1 Lytic transglycolase RseC_MucC PF04246.12 KLO16966.1 - 0.17 11.8 0.9 0.82 9.6 0.7 1.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Bromodomain PF00439.25 KLO16967.1 - 1.5e-23 82.7 0.5 1.5e-23 82.7 0.5 1.8 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 KLO16967.1 - 1.1e-06 28.9 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KLO16967.1 - 1.8e-05 24.7 0.0 3.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO16967.1 - 0.00019 21.8 0.2 0.00036 20.9 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain 2-Hacid_dh_C PF02826.19 KLO16968.1 - 9.3e-46 155.4 0.0 1.3e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KLO16968.1 - 6.7e-19 67.9 0.0 8.9e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KLO16968.1 - 2.1e-05 24.8 0.0 5.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 KLO16968.1 - 0.045 14.2 0.1 5.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding RNA_polI_A14 PF08203.11 KLO16969.1 - 0.097 13.4 0.0 0.15 12.8 0.0 1.2 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 eIF-3_zeta PF05091.12 KLO16971.1 - 0.2 10.6 4.1 0.29 10.1 4.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1180 PF06679.12 KLO16972.1 - 0.19 12.1 0.1 0.44 11.0 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) LAG1-DNAbind PF09271.11 KLO16974.1 - 1.6e-50 171.7 0.1 2.5e-50 171.0 0.1 1.3 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 KLO16974.1 - 2.9e-19 69.8 0.0 3.3e-18 66.4 0.0 2.5 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain Sperm_Ag_HE2 PF05324.13 KLO16975.1 - 0.043 14.3 0.1 0.08 13.4 0.1 1.4 1 0 0 1 1 1 0 Sperm antigen HE2 ABC_tran PF00005.27 KLO16981.1 - 6e-23 81.9 0.0 8.3e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KLO16981.1 - 4.7e-08 33.2 0.0 0.00082 19.3 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KLO16981.1 - 4.3e-05 23.1 0.0 0.091 12.2 0.8 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KLO16981.1 - 0.00071 19.4 0.0 0.00099 18.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 KLO16981.1 - 0.0046 17.3 0.0 0.026 14.9 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KLO16981.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KLO16981.1 - 0.017 14.8 0.0 0.055 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KLO16981.1 - 0.026 14.8 0.0 0.071 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KLO16981.1 - 0.064 13.7 0.3 0.12 12.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain MTS_N PF08468.11 KLO16981.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal AP_endonuc_2 PF01261.24 KLO16982.1 - 1.1e-26 93.7 0.0 1.4e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel zinc_ribbon_10 PF10058.9 KLO16983.1 - 1e-20 73.2 0.5 1.8e-20 72.4 0.5 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein ARS2 PF04959.13 KLO16983.1 - 0.0084 16.5 1.2 0.018 15.4 1.2 1.5 1 0 0 1 1 1 1 Arsenite-resistance protein 2 SMN PF06003.12 KLO16983.1 - 0.027 13.7 0.1 0.027 13.7 0.1 1.8 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) WD40 PF00400.32 KLO16984.1 - 3.1e-60 198.7 13.7 5.4e-09 36.5 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO16984.1 - 7.2e-23 80.7 1.2 0.00022 21.4 0.0 6.2 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO16984.1 - 2.3e-08 34.1 2.8 5.5e-05 23.1 0.3 3.6 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KLO16984.1 - 1.5e-07 31.0 0.1 3.9e-05 23.1 0.0 2.7 1 1 2 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 KLO16984.1 - 2.8e-07 29.8 0.2 0.011 14.7 0.0 3.2 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KLO16984.1 - 5.2e-07 28.7 7.9 0.16 10.6 0.1 5.3 1 1 5 6 6 6 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KLO16984.1 - 0.00025 20.1 0.4 0.16 10.8 0.0 3.2 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KLO16984.1 - 0.0012 17.3 0.0 0.01 14.2 0.0 2.1 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KLO16984.1 - 0.025 13.9 0.4 2.9 7.2 0.1 2.7 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.11 KLO16984.1 - 0.057 12.5 0.0 0.36 9.9 0.0 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Utp8 PF10395.9 KLO16984.1 - 0.21 10.0 0.0 0.6 8.5 0.0 1.6 1 1 1 2 2 2 0 Utp8 family CSN8_PSD8_EIF3K PF10075.9 KLO16985.1 - 7.6e-24 84.3 0.0 1.1e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Aa_trans PF01490.18 KLO16986.1 - 9.8e-55 185.9 19.2 1.2e-54 185.6 19.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KLO16986.1 - 0.00015 20.9 11.3 0.00038 19.6 11.3 1.8 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF3185 PF11381.8 KLO16986.1 - 0.23 11.5 4.4 2 8.5 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF373 PF04123.13 KLO16986.1 - 1.5 8.2 10.4 0.15 11.5 4.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF373) WAC_Acf1_DNA_bd PF10537.9 KLO16987.1 - 7.5e-36 122.7 1.1 3e-35 120.8 1.1 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KLO16987.1 - 9.1e-32 109.5 0.0 9.1e-32 109.5 0.0 3.2 3 2 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KLO16987.1 - 1.8e-12 47.4 0.1 4.7e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KLO16987.1 - 5.2e-07 29.0 0.0 1.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 CENP-H PF05837.12 KLO16987.1 - 0.021 15.2 0.8 0.021 15.2 0.8 4.3 3 1 1 4 4 4 0 Centromere protein H (CENP-H) DDHD PF02862.17 KLO16987.1 - 1.7 8.7 5.5 15 5.6 0.8 2.4 2 0 0 2 2 2 0 DDHD domain DUF3287 PF11690.8 KLO16987.1 - 2.8 7.7 6.4 4 7.2 3.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) RdRP PF05183.12 KLO16989.1 - 1.2e-171 572.3 0.0 1.5e-171 572.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.12 KLO16990.1 - 1.1e-169 565.8 0.0 1.4e-169 565.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sec7 PF01369.20 KLO16991.1 - 6.4e-32 110.7 0.0 9.8e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KLO16991.1 - 1.2e-09 38.6 0.0 2.8e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KLO16991.1 - 1.2e-09 38.6 0.0 2.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 PH domain Pescadillo_N PF06732.11 KLO16992.1 - 2.1e-122 408.0 0.0 2.1e-122 408.0 0.0 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KLO16992.1 - 3.6e-10 40.1 0.0 1.2e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KLO16992.1 - 0.0013 19.0 0.0 0.0037 17.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KLO16992.1 - 0.0061 16.8 0.0 0.02 15.1 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain LSM PF01423.22 KLO16993.1 - 2.5e-17 62.3 0.5 3.8e-17 61.7 0.5 1.3 1 0 0 1 1 1 1 LSM domain Propep_M14 PF02244.16 KLO16993.1 - 0.019 15.3 0.8 0.025 14.9 0.8 1.2 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Hfq PF17209.3 KLO16993.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Hfq protein GFO_IDH_MocA PF01408.22 KLO16994.1 - 2.8e-11 44.3 0.1 1.3e-10 42.2 0.1 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KLO16994.1 - 0.016 15.2 0.1 0.052 13.6 0.1 2.0 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain ILEI PF15711.5 KLO16994.1 - 0.11 13.0 0.0 2.9 8.4 0.0 2.8 3 0 0 3 3 3 0 Interleukin-like EMT inducer Sacchrp_dh_NADP PF03435.18 KLO16994.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF4645 PF15488.6 KLO16995.1 - 7.9 5.8 9.9 8.5 5.7 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) Cyclin_N PF00134.23 KLO16996.1 - 2.7e-36 124.1 0.6 2.7e-36 124.1 0.6 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KLO16996.1 - 2e-09 37.6 0.2 4.7e-09 36.4 0.2 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF5349 PF17298.2 KLO16996.1 - 0.089 12.5 4.7 0.13 12.0 4.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) UPF0240 PF06784.11 KLO16998.1 - 0.017 15.2 1.5 3.2 7.8 0.1 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) DUF2489 PF10675.9 KLO16998.1 - 4 7.4 8.1 0.13 12.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Complex1_LYR PF05347.15 KLO16999.1 - 1.4e-17 63.5 0.1 1.6e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KLO16999.1 - 0.0093 16.5 0.1 0.011 16.3 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Rad21_Rec8_N PF04825.13 KLO17000.1 - 2.7e-24 85.5 0.0 5.1e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KLO17000.1 - 9.8e-11 40.8 0.0 2.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Ntox15 PF15604.6 KLO17000.1 - 0.058 13.5 2.1 0.16 12.1 0.4 2.1 2 0 0 2 2 2 0 Novel toxin 15 SUIM_assoc PF16619.5 KLO17000.1 - 0.23 11.6 1.3 0.65 10.1 1.3 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 NUDIX PF00293.28 KLO17001.1 - 6.7e-27 94.1 0.0 9.1e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4281 PF14108.6 KLO17001.1 - 0.04 14.3 0.0 0.066 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) Ribosomal_S17_N PF16205.5 KLO17002.1 - 1.1e-31 108.9 1.3 2e-31 108.2 1.3 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KLO17002.1 - 2.4e-28 98.0 0.9 2.4e-28 98.0 0.9 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 Metallophos PF00149.28 KLO17003.1 - 1.5e-36 126.9 0.0 5.1e-36 125.1 0.0 1.8 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KLO17003.1 - 3.2e-16 59.5 0.0 5.8e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain WD40 PF00400.32 KLO17004.1 - 3.8e-11 43.4 5.1 1.7e-05 25.4 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat MPC PF03650.13 KLO17006.1 - 5.1e-36 123.2 0.2 6.1e-36 122.9 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DNA_ligase_A_M PF01068.21 KLO17007.1 - 3.9e-63 212.8 0.1 7.1e-63 211.9 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KLO17007.1 - 2.6e-44 151.6 1.8 4.7e-44 150.8 0.5 2.1 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KLO17007.1 - 9.9e-25 87.0 0.0 2.6e-24 85.7 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KLO17007.1 - 1e-05 25.9 0.1 2.1e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 KLO17007.1 - 0.013 15.5 0.1 5.6 7.1 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain Presenilin PF01080.17 KLO17007.1 - 2.9 6.6 3.8 4.3 6.0 3.8 1.3 1 0 0 1 1 1 0 Presenilin SET PF00856.28 KLO17008.1 - 2.6e-22 80.0 3.0 2.4e-21 76.9 0.2 2.5 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 KLO17008.1 - 1e-13 51.9 5.5 1e-13 51.9 5.5 2.6 2 1 0 2 2 2 1 Pre-SET motif Chromo PF00385.24 KLO17008.1 - 0.00055 19.8 5.5 0.0012 18.7 5.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1804 PF08822.11 KLO17008.1 - 0.8 9.7 2.7 2.8 7.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) EamA PF00892.20 KLO17009.1 - 4e-06 27.0 27.1 0.00022 21.4 1.9 3.4 4 0 0 4 4 4 2 EamA-like transporter family DUF5134 PF17197.4 KLO17009.1 - 0.049 13.5 0.3 0.12 12.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) Ribosomal_L36 PF00444.18 KLO17010.1 - 1.8e-18 66.5 9.8 2.7e-18 65.9 9.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 DHFR_1 PF00186.19 KLO17011.1 - 3.4e-29 101.6 0.0 1.6e-25 89.7 0.0 2.6 2 1 0 2 2 2 2 Dihydrofolate reductase RTA1 PF04479.13 KLO17012.1 - 2.6e-65 219.9 0.3 3.4e-65 219.5 0.3 1.1 1 0 0 1 1 1 1 RTA1 like protein RTA1 PF04479.13 KLO17013.1 - 1.6e-59 201.0 2.6 2.2e-59 200.5 2.6 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3487 PF11990.8 KLO17013.1 - 0.2 11.6 1.2 4.9 7.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) RTA1 PF04479.13 KLO17014.1 - 3.7e-61 206.4 8.9 5.8e-61 205.7 8.9 1.3 1 0 0 1 1 1 1 RTA1 like protein Isochorismatase PF00857.20 KLO17015.1 - 2.7e-26 92.8 0.0 4.3e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family OppC_N PF12911.7 KLO17016.1 - 0.0061 16.5 0.9 0.013 15.5 0.9 1.4 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C Galactosyl_T PF01762.21 KLO17017.1 - 4.9e-08 33.0 0.1 0.00035 20.5 0.0 2.6 2 1 0 2 2 2 2 Galactosyltransferase GST_N_3 PF13417.6 KLO17018.1 - 6e-06 26.6 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO17018.1 - 9.3e-06 25.6 0.0 3.4e-05 23.8 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KLO17018.1 - 6.4e-05 23.2 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO17018.1 - 0.0039 17.4 0.0 0.21 11.8 0.0 2.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO17018.1 - 0.035 14.3 0.0 0.2 11.8 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain p450 PF00067.22 KLO17020.1 - 4.3e-64 217.0 0.0 5.5e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SGS PF05002.15 KLO17022.1 - 3.2e-34 116.9 2.1 6.1e-34 116.0 2.1 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KLO17022.1 - 2e-09 38.3 0.0 3.1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 CS domain OppC_N PF12911.7 KLO17023.1 - 0.027 14.4 0.2 0.066 13.2 0.2 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PMP1_2 PF08114.11 KLO17023.1 - 0.28 10.9 2.2 0.57 10.0 2.2 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Plasmodium_Vir PF05795.11 KLO17023.1 - 5.7 6.3 7.2 46 3.3 7.1 2.1 1 1 0 1 1 1 0 Plasmodium vivax Vir protein SKG6 PF08693.10 KLO17023.1 - 8.8 5.8 8.0 0.32 10.4 1.3 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Ras PF00071.22 KLO17024.1 - 9.9e-55 184.5 0.0 1.2e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO17024.1 - 1.7e-32 112.2 0.0 2.4e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO17024.1 - 2.1e-12 46.8 0.0 2.8e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KLO17024.1 - 1.9e-05 24.3 0.0 0.00083 18.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KLO17024.1 - 0.00012 22.1 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KLO17024.1 - 0.00075 18.9 0.0 0.00092 18.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KLO17024.1 - 0.0033 17.0 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 KLO17024.1 - 0.0079 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KLO17024.1 - 0.0079 16.5 0.1 0.019 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO17024.1 - 0.014 15.8 0.2 0.045 14.1 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KLO17024.1 - 0.016 15.1 0.0 2 8.3 0.0 2.2 1 1 1 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 KLO17024.1 - 0.027 14.3 0.0 1.2 8.8 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KLO17024.1 - 0.036 14.0 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 KLO17024.1 - 0.064 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Septin PF00735.18 KLO17024.1 - 0.085 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Septin DUF2075 PF09848.9 KLO17024.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KLO17024.1 - 0.2 11.0 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 KaiC D-ser_dehydrat PF14031.6 KLO17025.1 - 2e-25 89.3 0.1 4.2e-24 85.0 0.1 2.9 2 1 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KLO17025.1 - 3.4e-13 49.7 0.0 4.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Abhydrolase_3 PF07859.13 KLO17026.1 - 1.2e-60 204.9 0.0 1.7e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KLO17026.1 - 1.6e-08 33.9 0.1 3.7e-08 32.7 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KLO17026.1 - 0.22 10.4 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase 4HBT_3 PF13622.6 KLO17027.1 - 7.8e-54 183.5 0.0 8.9e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KLO17027.1 - 1.2e-22 80.2 0.0 1.1e-17 64.1 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase DS PF01916.17 KLO17027.1 - 0.026 13.8 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase RRM_1 PF00076.22 KLO17028.1 - 1.9e-42 142.9 0.1 1e-19 70.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KLO17028.1 - 2e-13 51.2 1.9 1.6e-11 45.2 1.9 2.5 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 KLO17028.1 - 2.5e-08 33.9 0.3 0.00091 19.2 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 KLO17028.1 - 0.0009 19.1 0.0 1.2 9.0 0.0 2.8 2 1 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KLO17028.1 - 0.0058 16.2 0.0 1.3 8.6 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KLO17028.1 - 0.012 15.6 0.0 2.9 8.0 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KLO17028.1 - 0.11 12.6 0.1 46 4.2 0.0 3.1 3 0 0 3 3 3 0 Limkain b1 FimA PF16970.5 KLO17028.1 - 0.19 11.9 0.4 17 5.6 0.0 2.4 2 0 0 2 2 2 0 Type-1 fimbrial protein, A IlvN PF07991.12 KLO17029.1 - 1.8e-49 167.5 0.0 2.5e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KLO17029.1 - 8.5e-24 84.5 0.2 1.2e-23 84.0 0.2 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KLO17029.1 - 9.1e-10 39.0 0.0 1.9e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KLO17029.1 - 6.4e-06 26.4 0.0 1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KLO17029.1 - 0.00076 18.9 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KLO17029.1 - 0.04 14.0 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NTS_2 PF15448.6 KLO17029.1 - 0.051 14.0 0.8 0.12 12.8 0.8 1.6 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein NAD_Gly3P_dh_N PF01210.23 KLO17029.1 - 0.11 12.4 0.0 1.3 9.0 0.0 2.2 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short_C2 PF13561.6 KLO17030.1 - 1.7e-58 198.0 0.1 2e-58 197.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO17030.1 - 5.2e-45 153.3 0.1 7e-45 152.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO17030.1 - 2.7e-10 40.4 0.2 4.3e-10 39.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Cupin_2 PF07883.11 KLO17031.1 - 2.3e-06 27.2 0.0 4.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain GATase_4 PF13230.6 KLO17032.1 - 1.1e-20 73.7 0.0 2.6e-20 72.5 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KLO17032.1 - 3.4e-10 40.3 0.0 6.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain PGM_PMM_I PF02878.16 KLO17033.1 - 1.4e-14 54.0 0.5 2.1e-07 30.7 0.0 3.0 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KLO17033.1 - 8.4e-13 48.3 0.4 2e-12 47.1 0.4 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KLO17033.1 - 0.00035 21.1 0.0 0.0031 18.1 0.0 2.6 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF1793 PF08760.11 KLO17033.1 - 0.042 14.3 0.0 0.55 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1793) PGM_PMM_III PF02880.16 KLO17033.1 - 0.14 12.4 0.1 0.39 10.9 0.1 1.9 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SNAP PF14938.6 KLO17034.1 - 9.3e-93 310.7 15.5 1.1e-92 310.5 15.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KLO17034.1 - 5.2e-09 36.3 10.1 4.1e-05 23.8 1.9 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KLO17034.1 - 0.00055 19.8 6.8 0.011 15.7 0.1 4.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 KLO17034.1 - 0.014 15.6 12.9 0.46 10.8 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TetR_C_18 PF17923.1 KLO17034.1 - 0.058 13.9 0.8 0.23 12.0 0.2 2.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_1 PF00515.28 KLO17034.1 - 0.38 10.6 13.1 0.56 10.1 0.2 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KLO17034.1 - 1.6 9.0 16.5 0.84 9.9 0.2 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KLO17034.1 - 4.3 7.1 10.8 0.78 9.5 0.3 3.9 5 1 0 5 5 5 0 TPR repeat TPR_6 PF13174.6 KLO17034.1 - 4.9 8.0 14.0 2 9.3 0.3 5.2 5 1 2 7 7 7 0 Tetratricopeptide repeat RRP36 PF06102.12 KLO17037.1 - 4e-40 137.5 23.1 4e-40 137.5 23.1 2.1 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 Prominin PF05478.11 KLO17037.1 - 0.87 7.5 3.5 1.2 7.0 3.5 1.2 1 0 0 1 1 1 0 Prominin CorA PF01544.18 KLO17038.1 - 3.6e-21 75.7 2.4 1.8e-11 43.9 0.3 3.1 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF3040 PF11239.8 KLO17038.1 - 3.5 8.0 5.9 0.48 10.7 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Pex16 PF08610.10 KLO17040.1 - 7.5e-107 357.2 0.4 8.6e-107 357.0 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) ICE2 PF08426.10 KLO17041.1 - 6.8e-28 97.9 32.5 1.2e-17 64.1 19.2 2.8 1 1 1 2 2 2 2 ICE2 LMWPc PF01451.21 KLO17042.1 - 1.8e-41 141.8 0.0 2.1e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pox_MCEL PF03291.16 KLO17042.1 - 0.045 12.9 0.1 0.056 12.6 0.1 1.1 1 0 0 1 1 1 0 mRNA capping enzyme SH3BGR PF04908.15 KLO17043.1 - 1.2e-07 31.8 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein PhetRS_B1 PF18262.1 KLO17043.1 - 0.18 12.0 4.4 0.23 11.7 0.5 2.7 2 1 1 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain adh_short PF00106.25 KLO17044.1 - 3.8e-43 147.2 0.0 5.8e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO17044.1 - 1.5e-42 145.7 0.1 2.3e-42 145.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO17044.1 - 2.8e-08 33.9 0.0 5.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO17044.1 - 0.005 16.3 0.1 0.085 12.3 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KLO17044.1 - 0.018 14.3 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 KLO17044.1 - 0.053 12.9 0.0 0.12 11.7 0.0 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF1611 PF07755.11 KLO17044.1 - 0.14 11.4 0.2 0.57 9.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain PhyH PF05721.13 KLO17045.1 - 0.0002 21.7 0.0 0.00071 19.9 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2-Hacid_dh_C PF02826.19 KLO17046.1 - 1.8e-49 167.5 0.0 3.7e-49 166.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KLO17046.1 - 2.2e-31 108.3 0.0 3.4e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KLO17046.1 - 0.0027 17.9 0.0 0.006 16.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase His_biosynth PF00977.21 KLO17047.1 - 3.4e-43 147.8 0.0 5e-42 143.9 0.0 2.5 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KLO17047.1 - 1e-17 64.6 0.0 1.6e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KLO17047.1 - 1.7e-07 31.0 0.0 3.2e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 KLO17047.1 - 1e-06 28.7 0.0 0.00022 21.1 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 KLO17047.1 - 0.093 12.5 0.7 1.9 8.2 0.0 2.7 3 0 0 3 3 3 0 Peptidase C26 Pal1 PF08316.11 KLO17048.1 - 3.2e-16 60.3 0.6 1.2e-15 58.5 0.6 2.1 1 0 0 1 1 1 1 Pal1 cell morphology protein FA_desaturase PF00487.24 KLO17049.1 - 9.4e-25 87.9 25.1 1.4e-24 87.3 25.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KLO17049.1 - 4.3e-09 36.4 0.0 8.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HMG14_17 PF01101.18 KLO17051.1 - 0.038 15.0 6.7 0.061 14.3 6.7 1.3 1 0 0 1 1 1 0 HMG14 and HMG17 Meth_synt_2 PF01717.18 KLO17052.1 - 4.8e-12 45.8 0.0 5.2e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KLO17052.1 - 0.00057 19.5 0.0 0.055 13.0 0.0 2.5 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Meth_synt_2 PF01717.18 KLO17053.1 - 1.1e-14 54.5 0.0 1.1e-09 38.0 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KLO17053.1 - 5.3e-05 22.9 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Ribosomal_L13e PF01294.18 KLO17054.1 - 1.9e-78 262.4 3.3 2.9e-78 261.8 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L4 PF00573.22 KLO17055.1 - 2.6e-55 187.1 0.0 3.4e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.19 KLO17056.1 - 8.8e-31 106.9 1.3 1e-30 106.7 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRCT_2 PF16589.5 KLO17058.1 - 5.3e-15 55.6 0.0 4.7e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain TraT PF05818.12 KLO17058.1 - 0.16 11.7 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Mito_carr PF00153.27 KLO17059.1 - 4.8e-65 215.5 6.6 7.7e-24 83.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3089 PF11288.8 KLO17059.1 - 0.05 13.1 0.1 3.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) PINIT PF14324.6 KLO17060.1 - 2.5e-37 128.4 1.5 4.9e-37 127.5 1.5 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KLO17060.1 - 7.5e-18 64.0 7.8 1.3e-17 63.2 7.8 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KLO17060.1 - 8.6e-08 31.9 1.8 1.7e-07 30.9 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KLO17060.1 - 0.00063 19.4 0.7 0.0043 16.8 0.0 2.4 2 0 0 2 2 2 1 SAP domain Moulting_cycle PF04870.16 KLO17060.1 - 0.25 10.6 0.4 0.42 9.8 0.0 1.5 2 0 0 2 2 2 0 Moulting cycle CS PF04969.16 KLO17061.1 - 5.7e-19 68.9 0.4 5.7e-19 68.9 0.4 1.7 2 0 0 2 2 2 1 CS domain ResIII PF04851.15 KLO17062.1 - 1.6e-22 80.3 0.0 2.8e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KLO17062.1 - 9.3e-16 58.1 0.0 1.8e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO17062.1 - 1.4e-14 54.3 0.0 1.5e-13 51.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KLO17062.1 - 1.7e-05 23.7 0.0 2.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.9 KLO17062.1 - 0.00012 21.5 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KLO17062.1 - 0.00039 20.7 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 KLO17062.1 - 0.00039 20.1 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 KLO17062.1 - 0.0013 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase cobW PF02492.19 KLO17062.1 - 0.0051 16.4 0.0 0.0093 15.6 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DEAD_2 PF06733.15 KLO17062.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_11 PF13086.6 KLO17062.1 - 0.029 14.2 0.1 7.2 6.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 KLO17062.1 - 0.04 13.3 0.0 0.096 12.1 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein AAA_30 PF13604.6 KLO17062.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KLO17062.1 - 0.084 13.4 0.1 3.5 8.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter T2SSE PF00437.20 KLO17062.1 - 0.09 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Indigoidine_A PF04227.12 KLO17063.1 - 1e-118 396.0 0.0 1.6e-118 395.3 0.0 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KLO17063.1 - 6.1e-14 52.0 0.9 1.4e-07 31.1 0.2 3.1 2 1 1 3 3 3 2 pfkB family carbohydrate kinase MoaE PF02391.17 KLO17064.1 - 1.3e-39 135.0 0.1 1.6e-39 134.7 0.1 1.1 1 0 0 1 1 1 1 MoaE protein Serine_protease PF18405.1 KLO17064.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Gammaproteobacterial serine protease Beta_helix PF13229.6 KLO17065.1 - 0.0022 17.9 2.9 0.01 15.7 1.2 2.4 1 1 1 2 2 2 1 Right handed beta helix region Axin_b-cat_bind PF08833.10 KLO17065.1 - 0.0073 16.4 9.6 34 4.7 0.1 5.0 4 1 1 5 5 5 2 Axin beta-catenin binding domain Tropomodulin PF03250.14 KLO17065.1 - 0.012 15.6 0.8 2.2 8.3 0.0 2.9 1 1 2 3 3 3 0 Tropomodulin KAAG1 PF15354.6 KLO17065.1 - 0.98 10.0 13.4 13 6.4 0.3 4.5 3 1 2 5 5 5 0 Kidney-associated antigen 1 NUC153 PF08159.12 KLO17066.1 - 3.5e-14 52.3 15.1 7.6e-14 51.2 0.3 4.3 3 1 1 4 4 4 3 NUC153 domain Tim17 PF02466.19 KLO17067.1 - 1.6e-07 31.7 11.0 9.8e-07 29.1 10.2 2.4 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Aldedh PF00171.22 KLO17068.1 - 2e-131 438.7 0.1 2.6e-131 438.3 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KLO17068.1 - 0.098 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) GCIP PF13324.6 KLO17069.1 - 0.012 15.2 1.7 0.021 14.5 1.7 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RE_MjaI PF09568.10 KLO17069.1 - 0.19 11.5 1.3 3.8 7.3 0.5 2.7 2 0 0 2 2 2 0 MjaI restriction endonuclease CENP-B_dimeris PF09026.10 KLO17069.1 - 1.4 9.4 12.0 3.4 8.1 12.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KLO17069.1 - 7.4 4.5 10.6 13 3.8 10.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi TRAPPC-Trs85 PF12739.7 KLO17070.1 - 4.4e-37 128.0 0.0 5.7e-36 124.4 0.0 2.1 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 KLO17070.1 - 0.13 9.6 0.0 0.22 8.8 0.0 1.3 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit WW PF00397.26 KLO17071.1 - 0.035 14.2 1.1 0.035 14.2 1.1 2.3 2 0 0 2 2 2 0 WW domain MRNIP PF15749.5 KLO17072.1 - 0.063 14.0 2.1 0.085 13.6 0.1 2.1 2 0 0 2 2 2 0 MRN-interacting protein zf-BED PF02892.15 KLO17072.1 - 0.11 12.6 1.1 0.28 11.2 1.1 1.7 1 1 0 1 1 1 0 BED zinc finger LCCL PF03815.19 KLO17073.1 - 1.5e-14 53.9 0.0 2.7e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 LCCL domain YbjM PF11045.8 KLO17073.1 - 0.019 15.1 0.4 0.055 13.6 0.4 1.8 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae TraL PF07178.11 KLO17073.1 - 2.6 8.6 6.7 0.17 12.3 0.3 2.5 3 0 0 3 3 3 0 TraL protein Seipin PF06775.14 KLO17075.1 - 3.4e-21 76.3 0.1 1.3e-20 74.4 0.1 1.8 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) His_Phos_1 PF00300.22 KLO17076.1 - 5.3e-38 130.7 0.0 6.6e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pep3_Vps18 PF05131.14 KLO17077.1 - 1.4e-48 164.5 0.0 3e-48 163.4 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KLO17077.1 - 7.2e-08 32.4 7.7 4.8e-06 26.5 0.1 3.7 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 KLO17077.1 - 7.3e-05 23.2 0.0 0.00019 21.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 KLO17077.1 - 0.0024 17.7 2.0 0.0024 17.7 2.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO17077.1 - 0.0049 16.8 1.3 0.0049 16.8 1.3 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KLO17077.1 - 0.013 15.9 3.2 0.014 15.7 1.1 2.1 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 KLO17077.1 - 0.024 14.6 1.0 0.058 13.4 1.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KLO17077.1 - 0.032 13.9 1.0 0.071 12.7 1.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KLO17077.1 - 0.14 11.9 6.4 0.33 10.7 6.4 1.7 1 0 0 1 1 1 0 RING-like zinc finger Zf_RING PF16744.5 KLO17077.1 - 0.18 12.0 0.2 0.46 10.6 0.2 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger zf-rbx1 PF12678.7 KLO17077.1 - 6.5 7.1 5.9 1.2 9.4 1.2 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain Cgr1 PF03879.14 KLO17078.1 - 3.2e-30 104.7 29.2 3.7e-30 104.5 29.2 1.0 1 0 0 1 1 1 1 Cgr1 family Atg14 PF10186.9 KLO17078.1 - 7 5.6 14.4 7.9 5.5 14.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec39 PF08314.11 KLO17080.1 - 1.1e-93 315.1 0.0 2.2e-93 314.1 0.0 1.4 1 1 0 1 1 1 1 Secretory pathway protein Sec39 UreD PF01774.17 KLO17081.1 - 2.9e-68 230.0 0.1 3.4e-68 229.8 0.1 1.0 1 0 0 1 1 1 1 UreD urease accessory protein MscS_porin PF12795.7 KLO17082.1 - 0.00013 21.6 20.1 0.00013 21.6 20.1 6.1 1 1 3 5 5 5 1 Mechanosensitive ion channel porin domain Filament PF00038.21 KLO17082.1 - 0.00031 20.5 105.4 0.0047 16.6 41.8 4.5 1 1 3 4 4 4 2 Intermediate filament protein PI3K_P85_iSH2 PF16454.5 KLO17082.1 - 0.00036 20.2 9.2 0.00036 20.2 9.2 6.3 2 1 5 7 7 7 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF3584 PF12128.8 KLO17082.1 - 0.0016 16.1 33.9 0.0016 16.1 33.9 4.7 1 1 4 5 5 5 3 Protein of unknown function (DUF3584) ATG16 PF08614.11 KLO17082.1 - 0.01 16.1 11.2 0.01 16.1 11.2 8.0 2 1 6 8 8 8 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KLO17082.1 - 0.095 12.7 114.9 0.23 11.5 21.0 8.6 1 1 6 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KLO17082.1 - 0.64 10.1 70.5 0.032 14.3 5.8 8.1 2 1 8 10 10 10 0 Protein of unknown function (DUF1664) DUF1192 PF06698.11 KLO17082.1 - 0.97 9.5 0.0 0.97 9.5 0.0 9.9 7 2 3 10 10 10 0 Protein of unknown function (DUF1192) Spc7 PF08317.11 KLO17082.1 - 1.5 7.6 126.0 0.09 11.6 23.1 6.9 2 1 5 7 7 7 0 Spc7 kinetochore protein Fez1 PF06818.15 KLO17082.1 - 3.7 7.9 101.4 0.34 11.3 21.9 6.7 1 1 5 6 6 6 0 Fez1 Mito_carr PF00153.27 KLO17083.1 - 7.2e-33 112.4 6.6 6.1e-16 58.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.26 KLO17086.1 - 4.4e-12 45.7 15.3 0.00016 21.9 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO17086.1 - 1.1e-08 35.2 12.9 0.005 17.6 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KLO17086.1 - 2.2e-07 31.0 14.4 0.00021 21.6 0.4 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KLO17086.1 - 5.9e-06 26.1 3.0 0.003 17.5 0.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KLO17086.1 - 0.00021 21.6 6.0 0.03 14.7 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KLO17086.1 - 0.00054 20.2 6.6 0.059 13.7 0.0 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KLO17086.1 - 0.0064 17.1 9.1 0.6 10.8 2.7 3.5 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 KLO17086.1 - 0.018 15.0 2.3 0.029 14.3 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 KLO17086.1 - 0.022 15.2 5.7 0.55 10.7 0.5 2.4 1 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 KLO17086.1 - 0.027 14.8 3.6 0.1 12.9 2.2 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-TRAF PF02176.18 KLO17086.1 - 0.2 12.4 7.8 0.17 12.6 2.6 2.7 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 KLO17086.1 - 0.23 11.6 3.0 4.1 7.5 0.0 2.9 1 1 2 3 3 3 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 KLO17086.1 - 0.37 10.6 4.7 1.1 9.0 0.2 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type TPR_12 PF13424.6 KLO17087.1 - 4.5e-30 103.8 23.5 1.3e-07 31.8 1.3 7.4 6 1 1 7 7 7 5 Tetratricopeptide repeat SNAP PF14938.6 KLO17087.1 - 4.8e-10 39.3 12.8 0.0019 17.7 0.5 3.4 2 1 1 3 3 3 3 Soluble NSF attachment protein, SNAP AAA_16 PF13191.6 KLO17087.1 - 3.1e-09 37.4 1.7 4.1e-08 33.8 0.2 3.5 4 1 0 4 4 4 1 AAA ATPase domain TPR_10 PF13374.6 KLO17087.1 - 1.3e-06 28.1 15.5 0.015 15.2 0.0 6.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO17087.1 - 1.3e-06 28.0 12.8 0.057 13.5 0.6 8.1 8 0 0 8 8 7 1 Tetratricopeptide repeat AAA_22 PF13401.6 KLO17087.1 - 4.3e-05 23.8 0.0 0.00022 21.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KLO17087.1 - 9.2e-05 21.7 0.0 0.009 15.2 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain TPR_1 PF00515.28 KLO17087.1 - 0.0002 21.0 6.5 0.39 10.6 0.6 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat NACHT PF05729.12 KLO17087.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KLO17087.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2225 PF09986.9 KLO17087.1 - 0.049 13.4 0.9 5.7 6.6 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) RsgA_GTPase PF03193.16 KLO17087.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 KLO17087.1 - 0.12 12.9 0.0 0.43 11.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter TPR_21 PF09976.9 KLO17087.1 - 0.2 11.4 1.4 1.5 8.5 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain AAA_24 PF13479.6 KLO17087.1 - 0.22 11.2 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_16 PF13432.6 KLO17087.1 - 1.1 10.0 9.5 14 6.4 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DSS1_SEM1 PF05160.13 KLO17088.1 - 4.4e-23 81.1 6.7 6.4e-23 80.6 6.7 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Sugar_tr PF00083.24 KLO17089.1 - 4.7e-32 111.4 32.3 1.6e-17 63.5 9.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KLO17089.1 - 5.2e-19 68.4 45.1 8.3e-14 51.3 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NACHT PF05729.12 KLO17090.1 - 2.8e-05 24.1 2.1 0.00093 19.2 1.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KLO17090.1 - 0.00064 20.1 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KLO17090.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CbiA PF01656.23 KLO17090.1 - 0.19 11.8 0.1 0.41 10.7 0.1 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 KLO17091.1 - 9.8e-08 32.1 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO17091.1 - 0.00059 20.3 0.1 0.021 15.2 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KLO17091.1 - 0.06 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF443 PF04276.12 KLO17093.1 - 0.00053 19.9 0.8 0.41 10.4 0.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF443) NACHT PF05729.12 KLO17094.1 - 1.8e-06 27.9 0.0 1.1e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO17094.1 - 6.7e-05 23.3 0.0 0.00029 21.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KLO17094.1 - 0.00012 22.5 0.0 0.00029 21.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 KLO17094.1 - 0.0015 17.9 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain NB-ARC PF00931.22 KLO17094.1 - 0.082 12.1 0.2 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.14 KLO17094.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain F-box-like PF12937.7 KLO17096.1 - 3e-06 27.0 2.1 3e-06 27.0 2.1 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO17097.1 - 2.6e-05 24.0 0.9 0.098 12.6 0.1 2.6 2 0 0 2 2 2 2 F-box-like LRR_8 PF13855.6 KLO17097.1 - 0.027 14.2 0.1 23 4.8 0.0 3.7 4 0 0 4 4 4 0 Leucine rich repeat Methyltransf_25 PF13649.6 KLO17098.1 - 0.00022 21.9 0.1 0.0006 20.5 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO17098.1 - 0.015 15.9 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Aldo_ket_red PF00248.21 KLO17099.1 - 2.5e-47 161.5 0.0 2.3e-46 158.4 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.13 KLO17100.1 - 5.8e-11 42.4 0.0 8.7e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO17100.1 - 3.1e-10 40.2 0.0 5.4e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KLO17100.1 - 5.7e-08 32.5 0.0 2.4e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO17100.1 - 1.6e-07 30.6 0.0 1.8e-06 27.2 0.0 2.1 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KLO17100.1 - 3.5e-05 24.0 0.0 5.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KLO17100.1 - 0.0046 16.2 0.0 0.016 14.4 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KLO17100.1 - 0.018 14.2 0.0 0.068 12.3 0.0 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KLO17100.1 - 0.12 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KLO17100.1 - 0.17 12.0 0.4 1.2 9.2 0.0 2.5 2 1 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KLO17101.1 - 3.4e-08 33.6 0.2 5.8e-08 32.8 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KLO17101.1 - 3.5e-08 33.2 0.0 0.00028 20.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KLO17101.1 - 2.2e-06 27.4 0.1 3.3e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KLO17101.1 - 1.4e-05 24.3 0.0 3.1e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KLO17101.1 - 0.001 18.3 0.0 0.0022 17.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 KLO17101.1 - 0.0023 18.2 0.0 0.0057 16.9 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KLO17101.1 - 0.028 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.23 KLO17101.1 - 0.22 11.6 1.3 2.3 8.3 0.1 2.6 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain WD40 PF00400.32 KLO17102.1 - 2e-16 60.1 1.3 0.00032 21.4 0.2 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO17102.1 - 1.1e-08 35.2 0.3 0.00025 21.3 0.1 5.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO17102.1 - 0.018 15.0 0.0 0.57 10.0 0.0 2.8 2 2 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KLO17102.1 - 0.039 12.9 0.0 7.6 5.4 0.0 2.5 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FA_hydroxylase PF04116.13 KLO17103.1 - 1e-21 77.7 31.6 1.6e-21 77.1 27.1 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TatC PF00902.18 KLO17103.1 - 1.3 8.8 14.3 1.7 8.4 4.9 2.3 1 1 1 2 2 2 0 Sec-independent protein translocase protein (TatC) DUF1295 PF06966.12 KLO17104.1 - 1.5e-46 158.8 0.1 1.9e-46 158.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KLO17104.1 - 8.7e-05 22.5 0.8 0.0002 21.3 0.1 1.8 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KLO17104.1 - 0.0077 16.6 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KLO17104.1 - 0.012 16.0 0.1 0.042 14.3 0.1 2.0 1 1 0 1 1 1 0 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KLO17104.1 - 0.045 12.5 0.3 0.18 10.5 0.3 2.0 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family F-box-like PF12937.7 KLO17105.1 - 6.9e-06 25.9 0.1 2.1e-05 24.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO17105.1 - 1.6 9.2 11.2 1.6 9.3 0.4 5.1 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO17106.1 - 2.5e-06 27.3 0.1 7.2e-06 25.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO17106.1 - 0.016 15.7 9.2 1 9.9 0.3 5.0 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) Complex1_LYR PF05347.15 KLO17107.1 - 1.3e-13 50.8 1.5 1.5e-13 50.6 0.1 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KLO17107.1 - 3e-05 24.7 0.5 4.1e-05 24.3 0.5 1.3 1 1 0 1 1 1 1 Complex1_LYR-like RhoGAP PF00620.27 KLO17108.1 - 2.6e-39 134.5 0.0 5.9e-39 133.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 KLO17108.1 - 5.5e-12 46.2 0.0 2e-08 34.7 0.0 3.5 3 0 0 3 3 3 2 RasGEF domain PH_9 PF15410.6 KLO17108.1 - 1.2e-05 25.7 0.0 3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KLO17108.1 - 0.00014 22.3 0.0 0.0076 16.7 0.0 2.6 2 0 0 2 2 2 1 PH domain RasGEF_N PF00618.20 KLO17108.1 - 0.00019 21.6 0.4 0.005 17.0 0.1 3.4 2 1 0 2 2 2 1 RasGEF N-terminal motif Glyco_transf_22 PF03901.17 KLO17109.1 - 1.4e-32 113.5 20.0 1.9e-32 113.1 20.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ala_racemase_N PF01168.20 KLO17110.1 - 6.9e-18 65.1 0.0 1.1e-07 31.7 0.0 3.0 2 1 0 2 2 2 2 Alanine racemase, N-terminal domain UPF0014 PF03649.13 KLO17111.1 - 3.3e-69 232.9 18.2 4.3e-69 232.6 18.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) OATP PF03137.20 KLO17111.1 - 0.065 11.5 0.7 0.15 10.3 0.7 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 KLO17113.1 - 3.1e-44 151.3 0.0 5.7e-30 104.6 0.0 4.1 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KLO17113.1 - 1e-25 90.5 0.1 2e-20 73.2 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO17113.1 - 0.00061 18.7 0.0 0.0015 17.4 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO17113.1 - 0.0073 16.3 0.1 0.03 14.2 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO17113.1 - 0.052 12.8 0.0 3 7.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 KLO17113.1 - 0.14 11.8 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 RIO1 family SPRY PF00622.28 KLO17114.1 - 1.3e-06 28.5 0.0 2.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Lebercilin PF15619.6 KLO17115.1 - 0.067 12.8 32.5 0.021 14.5 26.9 2.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease YabA PF06156.13 KLO17115.1 - 0.29 11.8 19.3 0.11 13.1 9.0 3.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 KLO17115.1 - 0.47 9.8 24.0 2.9 7.1 23.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Propep_M14 PF02244.16 KLO17115.1 - 0.62 10.5 3.9 0.9 10.0 0.5 3.0 3 0 0 3 3 3 0 Carboxypeptidase activation peptide DMPK_coil PF08826.10 KLO17115.1 - 2.6 8.2 22.5 3.8 7.7 4.6 3.7 3 0 0 3 3 3 0 DMPK coiled coil domain like Nup54 PF13874.6 KLO17115.1 - 7.7 6.6 30.3 3.2 7.9 11.9 3.8 3 1 1 4 4 4 0 Nucleoporin complex subunit 54 SPG4 PF17325.2 KLO17116.1 - 0.01 16.9 0.0 0.021 15.9 0.0 1.4 1 0 0 1 1 1 0 Stationary phase protein 4 zf-MYND PF01753.18 KLO17117.1 - 1.9e-08 34.3 8.7 4.1e-08 33.2 8.7 1.6 1 0 0 1 1 1 1 MYND finger zf-RING_7 PF02591.15 KLO17117.1 - 3.5 7.9 5.9 6.6 7.0 0.1 2.9 2 0 0 2 2 2 0 C4-type zinc ribbon domain F-box-like PF12937.7 KLO17118.1 - 0.00046 20.0 0.0 0.041 13.8 0.0 2.6 2 0 0 2 2 2 2 F-box-like LRR_8 PF13855.6 KLO17118.1 - 0.033 14.0 0.3 0.51 10.1 0.0 3.0 3 0 0 3 3 3 0 Leucine rich repeat PrpF PF04303.13 KLO17119.1 - 1.1e-71 241.8 0.0 1.4e-71 241.4 0.0 1.1 1 0 0 1 1 1 1 PrpF protein Pkinase PF00069.25 KLO17120.1 - 1.3e-65 221.4 0.0 2e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO17120.1 - 1.6e-37 129.2 0.0 2.2e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO17120.1 - 4.2e-08 32.8 0.0 5.9e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO17120.1 - 8.2e-05 21.5 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO17120.1 - 0.0014 18.0 0.2 0.004 16.5 0.2 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO17120.1 - 0.0036 17.2 0.4 0.0061 16.5 0.4 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KLO17120.1 - 0.091 12.4 0.2 7.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PKD_channel PF08016.12 KLO17121.1 - 0.00098 17.9 1.2 0.00098 17.9 1.2 3.2 3 1 0 3 3 3 2 Polycystin cation channel CDC27 PF09507.10 KLO17123.1 - 1.7e-26 93.6 52.3 4.3e-26 92.3 52.3 1.6 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 DEAD PF00270.29 KLO17125.1 - 2.4e-39 134.9 0.0 6.5e-39 133.5 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO17125.1 - 8.9e-25 87.2 0.1 1.9e-23 82.9 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO17125.1 - 4.4e-08 33.3 0.0 9.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KLO17125.1 - 0.035 14.1 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.6 KLO17125.1 - 0.24 11.7 0.6 3.8 7.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain Myb_DNA-binding PF00249.31 KLO17126.1 - 0.0056 16.9 0.2 0.013 15.7 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain YscJ_FliF_C PF08345.11 KLO17126.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.4 3 0 0 3 3 3 0 Flagellar M-ring protein C-terminal Actin PF00022.19 KLO17127.1 - 6.4e-86 288.5 0.0 2.5e-84 283.3 0.0 2.0 1 1 0 1 1 1 1 Actin zf-MYND PF01753.18 KLO17128.1 - 3.5e-10 39.8 16.0 7.1e-10 38.8 16.0 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO17128.1 - 0.074 13.2 8.2 0.18 11.9 8.2 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Imm52 PF15579.6 KLO17128.1 - 0.086 12.7 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 52 Ecl1 PF12855.7 KLO17128.1 - 0.61 11.2 3.3 0.35 12.0 1.0 1.6 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins APG17 PF04108.12 KLO17130.1 - 6.7e-69 232.9 4.3 8e-69 232.7 4.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF1664 PF07889.12 KLO17130.1 - 0.3 11.1 4.8 2.1 8.4 0.1 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Rx_N PF18052.1 KLO17130.1 - 1.1 9.6 5.2 7.6 6.9 0.2 3.4 1 1 2 3 3 3 0 Rx N-terminal domain CENP-F_leu_zip PF10473.9 KLO17130.1 - 1.1 9.2 7.9 0.26 11.3 3.4 2.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 KLO17130.1 - 1.4 9.2 9.9 0.51 10.6 0.2 3.7 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF4763 PF15960.5 KLO17130.1 - 1.7 7.9 8.6 0.39 10.0 2.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4763) DUF508 PF04370.12 KLO17132.1 - 3.6 7.3 7.3 5.5 6.7 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) IMUP PF15761.5 KLO17132.1 - 6.1 7.6 9.1 8.9 7.1 9.1 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein DASH_Ask1 PF08655.10 KLO17134.1 - 7.4e-25 86.6 0.3 1.5e-24 85.6 0.3 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 Rad9 PF04139.13 KLO17135.1 - 7.3e-46 156.7 0.1 9.9e-46 156.2 0.1 1.2 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KLO17135.1 - 0.0013 17.9 0.2 0.015 14.4 0.1 2.1 2 0 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 DNA_pol3_delta2 PF13177.6 KLO17136.1 - 2.3e-13 50.3 0.1 5.3e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KLO17136.1 - 2.9e-05 24.5 1.2 9.6e-05 22.8 1.2 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KLO17136.1 - 3.2e-05 23.8 2.1 5.2e-05 23.1 2.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KLO17136.1 - 9.1e-05 22.8 0.5 0.00032 21.0 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 KLO17136.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KLO17136.1 - 0.01 16.2 0.1 0.029 14.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_assoc_2 PF16193.5 KLO17136.1 - 0.019 15.3 0.0 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_22 PF13401.6 KLO17136.1 - 0.062 13.6 1.6 1.3 9.3 0.9 2.8 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KLO17136.1 - 0.1 12.4 0.3 6.5 6.5 0.0 2.7 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain WD40 PF00400.32 KLO17137.1 - 2.5e-07 31.2 13.5 0.78 10.7 0.3 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO17137.1 - 0.0099 16.2 0.2 3.5 8.0 0.0 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain But2 PF09792.9 KLO17139.1 - 5.4e-05 23.6 0.0 8.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.8 KLO17140.1 - 2.6e-17 63.3 1.4 2.6e-17 63.3 1.4 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF3328) DUF1422 PF07226.11 KLO17140.1 - 0.027 14.5 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) DUF3328 PF11807.8 KLO17141.1 - 3.6e-13 49.8 2.0 4.7e-13 49.4 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) Glyco_hydro_115 PF15979.5 KLO17142.1 - 2.2e-133 444.9 0.4 3.9e-133 444.1 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KLO17142.1 - 9.4e-48 162.3 0.0 1.9e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Glyco_hydro_67N PF03648.14 KLO17142.1 - 0.0096 16.2 0.0 0.062 13.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 N-terminus DUF4662 PF15578.6 KLO17142.1 - 0.2 11.4 0.1 41 3.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4662) GGACT PF06094.12 KLO17143.1 - 2.3e-06 28.2 0.0 6.5e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like ECH_1 PF00378.20 KLO17144.1 - 4.7e-21 75.2 0.0 6.5e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KLO17144.1 - 2.8e-09 36.9 0.0 3.6e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Response_reg PF00072.24 KLO17145.1 - 3.9e-18 65.6 0.0 3.6e-17 62.5 0.0 2.5 2 1 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KLO17145.1 - 5.4e-17 62.3 0.2 1.2e-16 61.2 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KLO17145.1 - 4.1e-14 52.3 0.1 9.8e-14 51.2 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Cytochrom_B561 PF03188.16 KLO17146.1 - 5.8e-10 39.4 8.5 5.8e-10 39.4 8.5 2.3 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 MFS_2 PF13347.6 KLO17146.1 - 0.021 13.4 7.9 0.038 12.5 7.9 1.3 1 0 0 1 1 1 0 MFS/sugar transport protein NPDC1 PF06809.11 KLO17146.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) PilX_N PF14341.6 KLO17146.1 - 0.26 11.3 3.2 5.6 7.0 0.1 2.5 2 0 0 2 2 2 0 PilX N-terminal DUF4271 PF14093.6 KLO17146.1 - 2.4 8.0 5.9 1.5 8.7 2.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) CTU2 PF10288.9 KLO17147.1 - 4.6e-18 65.5 1.2 8.4e-18 64.6 0.0 2.0 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 PRK PF00485.18 KLO17148.1 - 1e-50 172.2 0.0 1.6e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KLO17148.1 - 8.5e-47 159.3 0.0 2.8e-44 151.1 0.0 2.3 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.6 KLO17148.1 - 6.2e-05 23.5 0.0 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KLO17148.1 - 0.00042 20.5 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KLO17148.1 - 0.002 17.5 0.0 0.0043 16.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin CoaE PF01121.20 KLO17148.1 - 0.025 14.3 0.0 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_17 PF13207.6 KLO17148.1 - 0.096 13.1 0.0 20 5.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain Cyclin_N PF00134.23 KLO17149.1 - 7.9e-44 148.5 0.1 3.3e-42 143.2 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KLO17149.1 - 2e-26 92.4 0.0 3.5e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain DNTTIP1_dimer PF18192.1 KLO17149.1 - 0.022 15.1 0.1 0.056 13.8 0.1 1.7 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain BRI3BP PF14965.6 KLO17149.1 - 0.057 12.9 0.1 0.087 12.3 0.1 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 p450 PF00067.22 KLO17150.1 - 8.2e-63 212.7 0.0 3.5e-62 210.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 KLO17151.1 - 1.6e-17 63.7 15.8 2.2e-17 63.2 15.8 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-C3HC PF07967.13 KLO17152.1 - 5.7e-27 94.4 0.2 4.5e-23 81.8 0.1 2.5 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KLO17152.1 - 2.5e-13 50.0 5.8 2.2e-10 40.6 0.1 3.3 3 0 0 3 3 3 2 Rsm1-like BIR PF00653.21 KLO17152.1 - 0.019 15.6 0.1 5.3 7.8 0.0 2.6 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain P53_C PF11619.8 KLO17152.1 - 0.064 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain DM PF00751.18 KLO17152.1 - 0.41 10.6 3.5 18 5.3 0.1 2.6 2 0 0 2 2 2 0 DM DNA binding domain DUF2370 PF10176.9 KLO17153.1 - 1.4e-70 237.4 0.0 3.1e-70 236.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF4064 PF13273.6 KLO17153.1 - 0.11 12.7 1.8 0.17 12.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) TMEM252 PF15664.5 KLO17153.1 - 0.23 11.2 0.9 3.7 7.3 0.2 2.5 2 0 0 2 2 2 0 Transmembrane protein 252 family Methyltransf_23 PF13489.6 KLO17154.1 - 1.9e-06 27.8 0.0 4.4e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO17154.1 - 0.00021 22.0 0.0 0.001 19.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KLO17154.1 - 0.0065 16.1 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 KLO17154.1 - 0.0096 16.6 0.0 1.3 9.8 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO17154.1 - 0.02 15.5 0.0 2.1 9.1 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KLO17154.1 - 0.022 14.7 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KLO17154.1 - 0.051 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ATP_synt_H PF05493.13 KLO17155.1 - 5.8e-19 68.3 6.6 6.7e-19 68.1 6.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit H HisKA_7TM PF16927.5 KLO17155.1 - 0.0052 16.8 2.7 0.0061 16.6 2.7 1.0 1 0 0 1 1 1 1 N-terminal 7TM region of histidine kinase DUF4131 PF13567.6 KLO17155.1 - 1.5 8.5 6.0 1.7 8.3 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Phage_holin_3_6 PF07332.11 KLO17155.1 - 2.5 8.1 7.1 2.9 8.0 7.1 1.0 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4307 PF14155.6 KLO17155.1 - 3.7 7.4 4.5 1.2 9.0 1.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) HLH PF00010.26 KLO17156.1 - 1.7e-05 24.7 0.0 6.5e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain NUDIX PF00293.28 KLO17157.1 - 1.1e-13 51.3 0.2 1.5e-13 50.9 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain Zip PF02535.22 KLO17158.1 - 5.5e-48 163.9 11.8 4.1e-45 154.4 11.8 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Carot_N PF09150.10 KLO17158.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal HD PF01966.22 KLO17159.1 - 0.00035 20.8 0.2 0.0015 18.7 0.2 2.0 1 1 0 1 1 1 1 HD domain Epimerase PF01370.21 KLO17162.1 - 5.7e-19 68.5 0.2 2.9e-18 66.2 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO17162.1 - 1.4e-12 47.2 1.1 2.6e-12 46.3 0.2 1.9 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KLO17162.1 - 2.4e-11 43.9 0.0 3.2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KLO17162.1 - 3e-10 39.7 0.0 0.00016 20.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 KLO17162.1 - 2.6e-08 33.7 0.0 1.3e-07 31.4 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KLO17162.1 - 3.4e-05 23.1 0.5 7.9e-05 21.9 0.5 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KLO17162.1 - 0.00014 21.4 0.1 0.00075 19.0 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Glyco_transf_20 PF00982.21 KLO17163.1 - 6.1e-184 612.1 0.0 1.4e-141 472.4 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 KLO17163.1 - 0.00051 20.5 0.1 0.001 19.5 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KLO17163.1 - 0.017 14.7 0.7 3 7.3 0.1 2.6 2 1 0 2 2 2 0 Glycosyl transferases group 1 Epimerase PF01370.21 KLO17164.1 - 1.1e-17 64.3 0.0 4.5e-16 59.0 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO17164.1 - 4.1e-11 42.4 0.0 1.3e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KLO17164.1 - 5.7e-10 39.4 0.0 1e-09 38.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KLO17164.1 - 9.3e-08 31.5 0.0 9.2e-06 25.0 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 KLO17164.1 - 2.4e-05 24.0 0.0 3.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KLO17164.1 - 4e-05 23.2 0.1 0.0015 18.0 0.1 2.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KLO17164.1 - 0.00011 21.7 0.0 0.0048 16.4 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KLO17164.1 - 0.00075 18.7 0.0 0.04 13.0 0.0 2.3 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 KLO17164.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus COesterase PF00135.28 KLO17165.1 - 6.9e-90 302.4 2.2 1e-88 298.5 2.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO17165.1 - 8e-10 38.9 1.3 9.4e-09 35.4 1.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fuseless PF15993.5 KLO17166.1 - 0.082 12.1 0.5 0.13 11.4 0.5 1.2 1 0 0 1 1 1 0 Fuseless An_peroxidase PF03098.15 KLO17167.1 - 1.5e-24 86.5 0.0 1.5e-18 66.7 0.0 3.5 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KLO17167.1 - 1.5e-07 30.6 0.0 1.4e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Cytochrome P450 Pkinase_Tyr PF07714.17 KLO17168.1 - 1.8e-37 129.0 0.0 2.5e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO17168.1 - 3.2e-37 128.4 0.0 4.4e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO17168.1 - 6.6e-05 22.4 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TMF_TATA_bd PF12325.8 KLO17169.1 - 0.067 13.4 1.7 6.3 7.0 0.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HR1 PF02185.16 KLO17169.1 - 0.26 11.4 2.6 16 5.7 0.7 2.7 2 1 1 3 3 3 0 Hr1 repeat BRO1 PF03097.18 KLO17172.1 - 3.8e-104 348.6 0.1 3.8e-104 348.6 0.1 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KLO17172.1 - 3.8e-73 246.4 7.0 7.9e-73 245.3 7.0 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV ThiD2 PF17792.1 KLO17172.1 - 0.042 14.3 2.1 0.1 13.1 0.5 2.5 2 0 0 2 2 2 0 ThiD2 family RAP80_UIM PF18282.1 KLO17172.1 - 0.15 11.8 3.8 4.4 7.1 0.2 2.8 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif Xpo1 PF08389.12 KLO17173.1 - 1.3e-21 77.2 1.0 3.1e-19 69.5 0.0 4.2 4 1 0 4 4 4 1 Exportin 1-like protein HEAT_EZ PF13513.6 KLO17173.1 - 0.0015 19.0 3.9 0.4 11.2 0.1 4.2 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.22 KLO17173.1 - 0.0056 16.8 0.7 0.059 13.6 0.0 3.1 2 0 0 2 2 2 1 HEAT repeat Cullin PF00888.22 KLO17174.1 - 1.9e-204 680.9 0.0 2.3e-204 680.5 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KLO17174.1 - 1.5e-27 95.4 4.3 1.5e-27 95.4 2.1 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 KLO17174.1 - 0.073 13.4 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 Penicillinase repressor SecA_SW PF07516.13 KLO17174.1 - 0.084 12.9 0.8 0.75 9.8 0.0 2.4 2 0 0 2 2 2 0 SecA Wing and Scaffold domain BCDHK_Adom3 PF10436.9 KLO17175.1 - 1.5e-38 132.2 0.0 2.1e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KLO17175.1 - 4.7e-09 36.7 0.0 3.6e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KLO17175.1 - 0.00014 21.7 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ATP-synt_ab PF00006.25 KLO17176.1 - 6.4e-109 362.6 0.0 8.8e-109 362.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KLO17176.1 - 2.2e-43 147.0 0.0 4.4e-43 146.0 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KLO17176.1 - 4.8e-14 52.6 3.6 1.4e-13 51.2 3.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DnaJ_C PF01556.18 KLO17178.1 - 6e-30 104.3 0.0 1e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KLO17178.1 - 6.2e-25 87.1 1.1 9.9e-25 86.4 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KLO17178.1 - 4.8e-14 52.5 16.3 8.9e-14 51.6 16.3 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KLO17178.1 - 8.8e-05 22.4 8.8 0.027 14.4 1.4 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KLO17178.1 - 0.00062 19.8 4.9 0.12 12.4 1.0 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KLO17178.1 - 0.66 9.6 5.6 0.34 10.5 0.3 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 KLO17178.1 - 2 8.8 11.4 1.4 9.3 0.3 3.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 KLO17178.1 - 3.3 7.8 9.9 29 4.8 10.1 2.1 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 KLO17178.1 - 4.4 7.6 11.0 16 5.9 0.0 4.1 3 1 1 4 4 4 0 zinc-ribbon NRDD PF13597.6 KLO17178.1 - 5 5.8 8.4 0.1 11.4 1.5 1.7 2 1 0 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase adh_short PF00106.25 KLO17179.1 - 1.7e-22 79.9 0.0 5.7e-22 78.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO17179.1 - 2.8e-13 50.0 0.0 5.1e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO17179.1 - 1.4e-11 44.6 0.3 2.3e-11 43.9 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO17179.1 - 8.3e-05 22.2 0.1 0.00025 20.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MoCF_biosynth PF00994.24 KLO17179.1 - 0.0028 17.3 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Probable molybdopterin binding domain THF_DHG_CYH_C PF02882.19 KLO17179.1 - 0.036 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RasGAP PF00616.19 KLO17180.1 - 1.8e-57 194.4 0.0 5.2e-57 192.9 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KLO17180.1 - 1.1e-35 122.8 1.0 1.1e-35 122.8 1.0 2.1 2 0 0 2 2 2 1 RasGAP C-terminus Connexin50 PF03509.14 KLO17180.1 - 0.13 13.1 0.0 0.76 10.6 0.1 2.3 2 0 0 2 2 2 0 Gap junction alpha-8 protein (Cx50) Herpes_UL14 PF03580.14 KLO17180.1 - 2.7 8.2 6.6 0.94 9.7 2.4 2.3 2 0 0 2 2 2 0 Herpesvirus UL14-like protein Asp PF00026.23 KLO17181.1 - 4.8e-42 144.5 0.0 6.7e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO17181.1 - 8.6e-09 35.9 1.4 1.9e-07 31.5 1.5 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KLO17181.1 - 0.0061 17.2 0.2 0.12 13.0 0.2 2.9 1 1 0 1 1 1 1 Aspartyl protease ParB PF08775.10 KLO17183.1 - 0.14 12.6 0.7 0.33 11.4 0.7 1.6 1 0 0 1 1 1 0 ParB family F-box-like PF12937.7 KLO17184.1 - 6.4e-06 26.0 0.2 2.2e-05 24.3 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO17184.1 - 0.019 14.8 0.0 0.056 13.3 0.0 1.8 1 0 0 1 1 1 0 F-box domain Fungal_trans PF04082.18 KLO17186.1 - 7.8e-11 41.5 0.4 1.5e-10 40.6 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO17186.1 - 2.6e-08 33.8 6.9 5.7e-08 32.8 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tat PF00539.18 KLO17186.1 - 0.9 9.7 7.6 0.39 10.9 3.6 2.2 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) Cellulase PF00150.18 KLO17187.1 - 1.4e-13 50.9 0.5 1.4e-13 50.9 0.5 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) WW PF00397.26 KLO17188.1 - 0.11 12.6 0.8 0.23 11.6 0.8 1.6 1 0 0 1 1 1 0 WW domain ADH_N_2 PF16884.5 KLO17194.1 - 2.3e-22 78.9 0.0 4.9e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KLO17194.1 - 7.3e-21 74.5 0.1 1.3e-20 73.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO17194.1 - 1.5e-09 39.0 0.0 3.8e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase LsmAD PF06741.13 KLO17196.1 - 2.2e-27 95.4 3.7 4.5e-27 94.4 3.7 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 KLO17196.1 - 1e-05 25.5 0.0 2.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 KLO17196.1 - 0.056 13.2 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 LSM domain LSM14 PF12701.7 KLO17196.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Scd6-like Sm domain ADH_N_2 PF16884.5 KLO17197.1 - 3.5e-27 94.4 0.0 7e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KLO17197.1 - 3.1e-20 72.5 0.1 5.1e-20 71.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO17197.1 - 4.8e-09 37.4 0.0 8.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MIP PF00230.20 KLO17199.1 - 4.6e-34 118.1 7.8 6.8e-34 117.5 7.8 1.2 1 0 0 1 1 1 1 Major intrinsic protein Plavaka PF18759.1 KLO17200.1 - 4.5e-111 371.2 0.0 5.9e-111 370.8 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase SMC_hinge PF06470.13 KLO17202.1 - 6.2e-23 81.3 0.0 1.7e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 KLO17202.1 - 0.00025 20.5 0.0 0.00025 20.5 0.0 3.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain Yqai PF09466.10 KLO17202.1 - 0.18 12.2 0.6 1.4 9.3 0.6 2.4 2 0 0 2 2 2 0 Hypothetical protein Yqai Mad3_BUB1_I PF08311.12 KLO17203.1 - 2.5e-28 98.5 0.6 5.5e-28 97.4 0.6 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KLO17203.1 - 1.3e-14 54.2 0.0 7.5e-14 51.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO17203.1 - 1.3e-06 27.9 0.0 2.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 KLO17203.1 - 0.0024 18.0 0.1 0.0047 17.0 0.1 1.4 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Phage_lambda_P PF06992.11 KLO17203.1 - 0.0085 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Replication protein P DUF713 PF05218.14 KLO17203.1 - 0.16 11.6 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF713) CENP-H PF05837.12 KLO17204.1 - 0.00047 20.5 8.0 0.00047 20.5 8.0 4.5 1 1 2 3 3 2 1 Centromere protein H (CENP-H) GAS PF13851.6 KLO17204.1 - 0.0026 17.2 8.3 0.0026 17.2 8.3 3.7 1 1 2 3 3 2 1 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 KLO17204.1 - 0.0045 17.0 7.1 0.0045 17.0 7.1 5.1 2 1 2 5 5 5 1 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 KLO17204.1 - 0.0048 15.8 18.7 0.0048 15.8 18.7 3.1 1 1 2 3 3 3 1 Spc7 kinetochore protein BST2 PF16716.5 KLO17204.1 - 0.016 15.8 6.9 0.016 15.8 6.9 5.6 2 2 4 6 6 5 0 Bone marrow stromal antigen 2 Gly_radical PF01228.21 KLO17204.1 - 0.09 13.3 0.6 0.42 11.2 0.3 2.4 1 1 0 1 1 1 0 Glycine radical CENP-F_leu_zip PF10473.9 KLO17204.1 - 0.1 12.7 60.2 0.17 11.9 22.3 4.7 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.20 KLO17204.1 - 0.15 11.4 55.6 0.085 12.2 28.0 4.0 1 1 1 2 2 2 0 Tropomyosin Titin_Ig-rpts PF06582.12 KLO17204.1 - 0.17 11.9 0.4 0.17 11.9 0.4 3.1 3 0 0 3 3 2 0 Titin repeat FlaC_arch PF05377.11 KLO17204.1 - 0.42 11.0 0.1 0.42 11.0 0.1 6.1 3 1 2 7 7 7 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.7 KLO17204.1 - 0.54 10.4 58.8 1.1 9.4 14.3 3.5 1 1 2 3 3 3 0 Tropomyosin like DUF1664 PF07889.12 KLO17204.1 - 0.61 10.1 27.5 0.85 9.7 0.5 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KLO17204.1 - 0.86 9.6 13.9 0.26 11.3 3.0 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nup54 PF13874.6 KLO17204.1 - 0.92 9.6 40.9 0.026 14.6 8.9 3.5 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 DUF3037 PF11236.8 KLO17204.1 - 1.4 9.4 17.3 0.49 10.8 1.6 3.9 2 1 3 5 5 5 0 Protein of unknown function (DUF3037) Flagellin_N PF00669.20 KLO17204.1 - 1.9 8.6 20.1 0.2 11.7 6.5 3.9 2 2 2 4 4 4 0 Bacterial flagellin N-terminal helical region CALCOCO1 PF07888.11 KLO17204.1 - 5.1 5.9 57.4 4.3 6.1 20.7 3.3 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like ERM PF00769.19 KLO17204.1 - 9.3 6.0 56.1 0.91 9.3 36.2 2.5 2 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF3138 PF11336.8 KLO17204.1 - 9.5 4.7 6.1 14 4.1 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Alpha-amylase PF00128.24 KLO17207.1 - 6e-23 81.9 0.0 4.7e-22 79.0 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KLO17207.1 - 9.2e-08 30.8 0.2 0.001 17.3 0.1 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 KLO17207.1 - 0.12 12.6 0.0 0.36 11.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) Sugar_tr PF00083.24 KLO17208.1 - 5.6e-83 279.3 17.8 6.7e-83 279.0 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO17208.1 - 9.3e-24 84.0 31.7 2.8e-21 75.8 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4952 PF16310.5 KLO17209.1 - 0.028 14.6 0.6 8 6.8 0.1 2.2 1 1 1 2 2 2 0 Domian of unknown function (DUF4952) DUF4141 PF13605.6 KLO17210.1 - 0.026 13.8 0.3 0.089 12.0 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) Glycophorin_A PF01102.18 KLO17210.1 - 3.5 7.9 6.5 8.2 6.7 6.5 1.7 1 1 0 1 1 1 0 Glycophorin A SOG2 PF10428.9 KLO17210.1 - 6.5 5.8 10.0 7.2 5.7 10.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Exo_endo_phos PF03372.23 KLO17211.1 - 0.037 13.5 0.2 0.07 12.6 0.2 1.5 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RhoGEF PF00621.20 KLO17212.1 - 8.6e-32 110.8 0.1 1.4e-31 110.1 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 KLO17212.1 - 1.7e-30 106.6 0.0 2.4e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KLO17212.1 - 2.2e-08 34.3 0.2 2.4e-07 30.9 0.1 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KLO17212.1 - 0.00039 20.9 0.0 0.0012 19.3 0.0 1.9 1 1 0 1 1 1 1 PH domain SinI PF08671.10 KLO17212.1 - 0.067 13.0 0.5 0.14 12.0 0.5 1.5 1 0 0 1 1 1 0 Anti-repressor SinI PH_16 PF17838.1 KLO17212.1 - 0.072 12.9 0.2 9.1 6.2 0.0 2.3 2 0 0 2 2 2 0 PH domain MFS_1 PF07690.16 KLO17213.1 - 8e-18 64.5 27.8 1.1e-16 60.7 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KLO17213.1 - 1.1e-09 38.2 0.8 2.7e-09 36.9 0.8 1.6 1 0 0 1 1 1 1 Nodulin-like DEAD PF00270.29 KLO17214.1 - 1.5e-45 155.1 0.0 6.8e-45 153.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO17214.1 - 1.8e-28 99.1 1.1 9.7e-28 96.7 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO17214.1 - 0.00036 20.6 0.1 0.0016 18.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HEM4 PF02602.15 KLO17214.1 - 0.05 12.9 0.3 0.082 12.2 0.3 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Acetyltransf_3 PF13302.7 KLO17215.1 - 1.5e-13 51.6 0.0 1.1e-11 45.6 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain SAF PF08666.12 KLO17215.1 - 0.16 12.6 0.1 0.7 10.6 0.0 2.0 2 0 0 2 2 2 0 SAF domain Thioredoxin PF00085.20 KLO17216.1 - 5.2e-56 187.0 0.3 2.5e-27 94.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KLO17216.1 - 5.2e-24 85.0 0.9 5.2e-24 85.0 0.9 2.6 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KLO17216.1 - 1.5e-18 67.2 0.3 2.2e-09 37.7 0.1 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KLO17216.1 - 9e-17 61.3 0.0 9.5e-09 35.0 0.0 2.4 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KLO17216.1 - 1.3e-10 41.3 0.1 0.00014 22.0 0.1 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KLO17216.1 - 1.5e-10 41.2 0.1 0.01 16.2 0.0 4.4 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_6 PF13848.6 KLO17216.1 - 3.1e-10 40.3 1.1 0.0065 16.4 0.1 4.2 3 1 1 4 4 4 2 Thioredoxin-like domain AhpC-TSA PF00578.21 KLO17216.1 - 8.9e-10 38.6 2.3 0.00014 21.7 0.0 3.8 4 0 0 4 4 4 2 AhpC/TSA family TraF PF13728.6 KLO17216.1 - 2e-08 34.4 1.5 0.0065 16.3 0.1 2.7 3 0 0 3 3 3 2 F plasmid transfer operon protein ERp29_N PF07912.13 KLO17216.1 - 5.5e-07 29.8 3.2 0.011 15.9 0.0 2.6 3 0 0 3 3 3 2 ERp29, N-terminal domain Redoxin PF08534.10 KLO17216.1 - 8.8e-07 28.7 0.7 0.0071 16.1 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 KLO17216.1 - 0.00027 20.7 2.5 0.054 13.3 0.0 3.0 3 1 1 4 4 4 2 Thioredoxin HyaE PF07449.11 KLO17216.1 - 0.0011 18.9 0.0 0.066 13.2 0.0 2.7 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 KLO17216.1 - 0.0059 16.8 2.7 0.33 11.2 0.2 3.0 2 2 0 2 2 2 1 Glutaredoxin Thioredoxin_5 PF13743.6 KLO17216.1 - 0.094 12.4 5.7 0.82 9.3 0.0 4.0 3 3 3 6 6 6 0 Thioredoxin T4_Rnl2_C PF18043.1 KLO17216.1 - 0.3 11.3 4.5 0.19 11.9 2.4 1.8 2 0 0 2 2 1 0 T4 RNA ligase 2 C-terminal Thioredoxin_4 PF13462.6 KLO17216.1 - 0.31 11.2 10.9 6.9 6.8 0.1 4.2 3 2 2 5 5 5 0 Thioredoxin WD40 PF00400.32 KLO17217.1 - 1.2e-34 117.7 16.4 2.1e-09 37.8 0.1 8.3 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO17217.1 - 1.4e-12 47.8 0.0 1.5e-06 28.4 0.0 4.8 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO17217.1 - 9.7e-05 21.5 0.1 0.0033 16.5 0.0 2.6 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KLO17217.1 - 0.057 12.7 0.0 1.1 8.6 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain WD40_3 PF15911.5 KLO17217.1 - 0.072 13.1 0.0 39 4.4 0.0 3.6 3 1 1 4 4 4 0 WD domain, G-beta repeat WDCP PF15390.6 KLO17217.1 - 0.21 10.0 0.0 0.32 9.3 0.0 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Acetyltransf_3 PF13302.7 KLO17218.1 - 7.9e-12 46.0 0.0 1.1e-11 45.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RNase_HII PF01351.18 KLO17219.1 - 2.4e-48 164.6 0.0 3.3e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII MpPF26 PF07666.11 KLO17221.1 - 0.11 12.6 2.5 0.9 9.7 0.2 2.2 2 1 0 2 2 2 0 M penetrans paralogue family 26 SART-1 PF03343.13 KLO17222.1 - 4e-165 550.9 69.0 4e-165 550.9 69.0 1.9 2 0 0 2 2 2 2 SART-1 family DUF155 PF02582.14 KLO17223.1 - 1.3e-44 152.4 0.0 1.9e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Tricorn_C1 PF14684.6 KLO17223.1 - 0.19 11.8 0.1 4.3 7.5 0.1 2.2 2 0 0 2 2 2 0 Tricorn protease C1 domain TPR_19 PF14559.6 KLO17224.1 - 6.2e-11 42.6 4.5 7e-06 26.5 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KLO17224.1 - 7.1e-10 39.4 0.4 0.04 14.6 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KLO17224.1 - 6.3e-06 26.2 0.1 0.11 13.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO17224.1 - 1.7e-05 24.9 1.2 0.037 14.3 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KLO17224.1 - 2.7e-05 23.9 3.7 3 8.2 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KLO17224.1 - 0.00012 22.6 2.3 5.6 8.1 0.0 5.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KLO17224.1 - 0.00015 21.4 3.9 11 6.1 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KLO17224.1 - 0.00016 21.9 3.3 0.11 12.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KLO17224.1 - 0.00024 21.6 0.3 0.4 11.1 0.0 2.4 2 0 0 2 2 2 2 Alkyl sulfatase dimerisation TPR_6 PF13174.6 KLO17224.1 - 0.0033 18.0 2.9 0.68 10.7 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KLO17224.1 - 0.0051 16.9 1.9 11 6.6 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KLO17224.1 - 0.0099 16.0 0.6 0.7 10.1 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KLO17224.1 - 0.025 14.7 0.3 2.6 8.2 0.0 3.4 3 1 1 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_22 PF18833.1 KLO17224.1 - 0.052 13.7 0.5 0.85 9.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KLO17224.1 - 0.26 10.6 4.3 1.4 8.3 0.1 3.3 4 0 0 4 4 4 0 Coatomer epsilon subunit AUX_IAA PF02309.16 KLO17225.1 - 0.063 13.1 0.2 0.094 12.6 0.2 1.2 1 0 0 1 1 1 0 AUX/IAA family Svf1_C PF17187.4 KLO17226.1 - 1.7e-46 158.1 0.0 2.2e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KLO17226.1 - 1.3e-40 139.1 0.0 1.8e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain FmdA_AmdA PF03069.15 KLO17227.1 - 3.9e-163 542.6 0.0 4.5e-163 542.4 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Arrestin_N PF00339.29 KLO17228.1 - 1.1e-05 25.5 0.0 3.6e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KLO17228.1 - 0.018 15.5 0.0 0.4 11.1 0.0 2.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain KH_6 PF15985.5 KLO17228.1 - 0.032 14.6 0.2 0.062 13.7 0.2 1.5 1 0 0 1 1 1 0 KH domain CreD PF06123.12 KLO17230.1 - 0.029 13.2 0.6 0.029 13.2 0.6 1.4 2 0 0 2 2 2 0 Inner membrane protein CreD Aconitase PF00330.20 KLO17231.1 - 5.8e-111 371.7 0.1 7.5e-110 368.1 0.1 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KLO17231.1 - 1.6e-20 73.8 0.0 4.8e-20 72.2 0.0 1.8 1 1 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KLO17231.1 - 0.054 12.2 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) TauD PF02668.16 KLO17232.1 - 5e-38 131.4 0.1 7.9e-38 130.8 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KLO17232.1 - 8.3e-16 58.4 0.2 1.6e-15 57.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KLO17232.1 - 4.9e-05 22.6 0.1 0.012 14.8 0.0 2.1 2 0 0 2 2 2 2 CsiD DUF3914 PF13053.6 KLO17232.1 - 0.12 12.7 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) RabGAP-TBC PF00566.18 KLO17233.1 - 1.4e-51 175.3 0.0 7.1e-51 172.9 0.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain COX6B PF02297.17 KLO17234.1 - 5.5e-22 77.8 2.1 7.6e-22 77.3 2.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Sugar_tr PF00083.24 KLO17236.1 - 7e-52 176.8 20.7 9.7e-52 176.3 20.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO17236.1 - 4.8e-20 71.8 23.9 4.8e-20 71.8 23.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DPBB_1 PF03330.18 KLO17238.1 - 8.3e-05 22.8 0.0 9.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Lytic transglycolase DUF1748 PF08520.10 KLO17240.1 - 1.8e-24 85.4 0.0 2e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Enolase_C PF00113.22 KLO17242.1 - 1.8e-142 473.9 0.1 2.5e-142 473.4 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KLO17242.1 - 3.7e-58 195.3 0.1 6.9e-58 194.5 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KLO17242.1 - 2e-07 30.8 0.0 5.3e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KLO17242.1 - 0.0021 17.3 0.4 0.0041 16.3 0.4 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus IlvN PF07991.12 KLO17243.1 - 9.5e-47 158.6 0.0 1.8e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KLO17243.1 - 1.3e-39 135.8 0.0 2.1e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 KLO17243.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Abhydrolase_6 PF12697.7 KLO17244.1 - 1.3e-26 94.6 0.4 1.8e-26 94.1 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO17244.1 - 3.3e-07 30.2 0.0 3.6e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO17244.1 - 1.4e-05 24.5 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KLO17244.1 - 0.027 14.6 0.0 0.17 11.9 0.0 2.2 2 1 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 KLO17244.1 - 0.047 13.4 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein AAA PF00004.29 KLO17245.1 - 3.9e-93 308.8 0.0 2e-46 157.7 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KLO17245.1 - 3.5e-20 71.5 0.1 5.2e-09 35.8 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KLO17245.1 - 5.7e-15 55.4 0.0 1.6e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KLO17245.1 - 2.4e-14 54.1 0.5 0.00048 20.5 0.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KLO17245.1 - 2.3e-13 50.6 0.0 0.0033 17.7 0.0 5.7 3 2 1 4 4 4 2 AAA domain AAA_5 PF07728.14 KLO17245.1 - 1.6e-10 41.1 0.3 0.001 19.0 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KLO17245.1 - 2.9e-09 37.3 0.0 0.0011 19.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KLO17245.1 - 5e-09 36.5 0.0 0.00061 20.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KLO17245.1 - 7.9e-09 35.2 0.0 0.00028 20.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KLO17245.1 - 2.1e-08 34.3 0.0 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KLO17245.1 - 3.1e-07 30.7 0.0 0.047 14.1 0.0 2.8 2 1 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 KLO17245.1 - 5.6e-07 29.2 0.1 0.034 13.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KLO17245.1 - 2.8e-06 27.2 0.0 0.094 12.4 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 KLO17245.1 - 4.2e-06 26.8 0.2 0.1 12.5 0.0 3.5 3 1 0 3 3 2 2 NACHT domain AAA_3 PF07726.11 KLO17245.1 - 5.3e-06 26.3 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KLO17245.1 - 7.1e-06 26.6 0.0 0.08 13.5 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_28 PF13521.6 KLO17245.1 - 7.1e-06 26.4 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KLO17245.1 - 2.5e-05 24.1 0.0 0.4 10.4 0.0 3.8 4 1 0 4 4 3 2 Sigma-54 interaction domain TsaE PF02367.17 KLO17245.1 - 2.6e-05 24.2 0.0 0.23 11.5 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KLO17245.1 - 3.3e-05 23.5 0.0 0.17 11.4 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 KLO17245.1 - 3.7e-05 23.1 0.0 0.21 10.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Sigma54_activ_2 PF14532.6 KLO17245.1 - 4.3e-05 23.6 0.0 2.3 8.4 0.0 3.4 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_18 PF13238.6 KLO17245.1 - 4.4e-05 24.0 0.0 0.32 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KLO17245.1 - 0.00011 21.8 3.0 3.8 7.0 0.1 4.2 2 2 1 4 4 4 0 AAA domain Cytidylate_kin2 PF13189.6 KLO17245.1 - 0.00014 22.1 0.0 0.015 15.4 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family ATPase PF06745.13 KLO17245.1 - 0.00018 21.0 0.1 2.4 7.5 0.0 3.1 2 1 0 3 3 3 2 KaiC AAA_17 PF13207.6 KLO17245.1 - 0.00019 21.8 0.0 0.18 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KLO17245.1 - 0.00033 19.9 0.0 0.83 8.8 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ATPase_2 PF01637.18 KLO17245.1 - 0.00035 20.6 0.0 2.6 7.9 0.0 3.1 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KLO17245.1 - 0.00043 20.1 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 KLO17245.1 - 0.00064 19.7 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_11 PF13086.6 KLO17245.1 - 0.00099 19.0 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 KLO17245.1 - 0.0012 18.0 0.0 0.052 12.7 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 KLO17245.1 - 0.0014 17.8 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KLO17245.1 - 0.0037 17.0 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KLO17245.1 - 0.0042 16.6 0.0 2.9 7.3 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Bac_DnaA PF00308.18 KLO17245.1 - 0.0056 16.5 0.0 4.7 7.0 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein AFG1_ATPase PF03969.16 KLO17245.1 - 0.0067 15.4 0.0 2.9 6.7 0.0 2.5 2 0 0 2 2 2 1 AFG1-like ATPase CPT PF07931.12 KLO17245.1 - 0.0082 16.0 0.0 0.64 9.8 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.9 KLO17245.1 - 0.013 14.8 0.0 0.77 8.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SKI PF01202.22 KLO17245.1 - 0.019 15.1 0.0 6.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_19 PF13245.6 KLO17245.1 - 0.028 14.7 0.5 11 6.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KLO17245.1 - 0.028 14.3 0.1 9.1 6.2 0.0 2.7 3 0 0 3 3 2 0 NTPase SRPRB PF09439.10 KLO17245.1 - 0.047 13.1 0.0 9.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KLO17245.1 - 0.054 13.2 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 KLO17245.1 - 0.081 12.3 0.0 25 4.2 0.0 3.3 2 1 0 3 3 3 0 Bacterial TniB protein Vps4_C PF09336.10 KLO17245.1 - 0.12 12.4 0.1 12 6.0 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain MMR_HSR1 PF01926.23 KLO17245.1 - 0.13 12.4 0.0 5.2 7.2 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Serinc PF03348.15 KLO17246.1 - 1.2e-160 535.1 7.2 1.4e-160 534.9 7.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Mntp PF02659.15 KLO17246.1 - 2.6 7.8 10.8 0.54 10.0 0.7 3.3 3 0 0 3 3 3 0 Putative manganese efflux pump Rad51 PF08423.11 KLO17247.1 - 6.5e-14 51.8 0.0 9.4e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KLO17247.1 - 0.00053 19.6 0.1 0.0012 18.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain Gti1_Pac2 PF09729.9 KLO17252.1 - 4.3e-49 167.1 1.3 2.5e-38 132.0 0.3 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family Tfb2 PF03849.14 KLO17254.1 - 3.3e-123 411.2 0.0 5e-123 410.6 0.0 1.3 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KLO17254.1 - 1.1e-26 93.1 0.2 2.4e-26 91.9 0.2 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KLO17254.1 - 0.00098 19.3 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GRIP PF01465.20 KLO17254.1 - 0.019 14.9 1.9 0.07 13.0 1.8 2.0 2 0 0 2 2 2 0 GRIP domain Ank_5 PF13857.6 KLO17255.1 - 8.3e-16 57.8 0.4 3.3e-12 46.4 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KLO17255.1 - 2.8e-13 50.2 0.5 1.5e-12 47.9 0.5 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KLO17255.1 - 2.4e-11 42.8 0.7 2.9e-06 27.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KLO17255.1 - 2.3e-10 40.4 1.8 6.5e-08 32.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KLO17255.1 - 3.1e-10 40.4 0.2 0.00031 21.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KLO17256.1 - 4.9e-15 55.4 0.0 2.8e-07 30.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KLO17256.1 - 5.4e-11 42.4 0.2 0.005 17.2 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KLO17256.1 - 1.5e-10 41.4 0.1 2.7e-05 24.6 0.0 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KLO17256.1 - 1.7e-10 41.3 0.0 2.5e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KLO17256.1 - 1.3e-09 37.5 0.0 0.0021 18.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Glyoxalase_6 PF18029.1 KLO17256.1 - 0.051 14.4 0.2 0.065 14.0 0.2 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain She9_MDM33 PF05546.11 KLO17257.1 - 7.1e-72 241.4 7.2 1.1e-71 240.8 7.2 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family DUF1110 PF06533.12 KLO17257.1 - 0.026 14.5 2.8 0.051 13.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1110) Uso1_p115_C PF04871.13 KLO17257.1 - 0.028 14.8 2.1 0.028 14.8 2.1 2.4 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region EVC2_like PF12297.8 KLO17257.1 - 0.11 11.2 7.6 0.16 10.6 7.6 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein FAD_binding_1 PF00667.20 KLO17258.1 - 6.5e-54 182.8 0.0 3.6e-53 180.4 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KLO17258.1 - 5.7e-32 110.9 0.5 9.3e-32 110.2 0.5 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KLO17258.1 - 9.8e-23 80.9 0.0 5.1e-22 78.6 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DASH_Dad1 PF08649.10 KLO17259.1 - 5.1e-21 74.6 0.2 6.3e-21 74.3 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Pkinase PF00069.25 KLO17260.1 - 2.2e-62 210.8 0.0 4.3e-62 209.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO17260.1 - 6.2e-35 120.7 0.0 1.2e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KLO17260.1 - 8e-22 77.1 11.9 6.1e-13 48.7 1.9 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KLO17260.1 - 9.5e-20 70.2 28.8 1.5e-11 44.0 10.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KLO17260.1 - 1.8e-10 41.3 0.8 1.8e-10 41.3 0.8 3.0 3 0 0 3 3 3 1 Protein kinase C terminal domain C2 PF00168.30 KLO17260.1 - 6.5e-09 36.0 0.1 1.2e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 C2 domain Peptidase_M6 PF05547.11 KLO17260.1 - 0.072 11.4 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 FTA2 PF13095.6 KLO17260.1 - 0.094 12.3 0.2 1.7 8.2 0.1 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 C1_2 PF03107.16 KLO17260.1 - 5.9 7.3 23.0 2.6 8.4 8.2 2.5 2 0 0 2 2 2 0 C1 domain Endosulfine PF04667.17 KLO17262.1 - 9.1e-25 86.6 1.4 1.5e-24 85.9 0.2 1.8 1 1 1 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF1176 PF06674.11 KLO17262.1 - 0.22 10.9 0.9 0.25 10.7 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) DEAD PF00270.29 KLO17264.1 - 3.2e-06 27.0 0.3 3.5e-06 26.9 0.3 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KLO17264.1 - 0.015 14.8 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain MspA PF09203.11 KLO17264.1 - 0.027 14.3 0.1 0.027 14.3 0.1 1.0 1 0 0 1 1 1 0 MspA Tir_receptor_C PF07489.11 KLO17264.1 - 0.028 14.4 0.1 0.03 14.3 0.1 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Kinesin PF00225.23 KLO17264.1 - 0.052 12.5 0.0 0.053 12.4 0.0 1.0 1 0 0 1 1 1 0 Kinesin motor domain DNA_pol_E_B PF04042.16 KLO17265.1 - 5.9e-28 97.7 1.5 8.4e-28 97.2 1.5 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 KLO17265.1 - 2.3e-09 37.6 0.0 1.8e-05 24.8 0.0 2.5 2 1 1 3 3 3 2 DNA polymerase alpha subunit B N-terminal GCP_C_terminal PF04130.13 KLO17265.1 - 0.17 11.4 0.1 0.34 10.3 0.1 1.4 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal RasGEF PF00617.19 KLO17266.1 - 1.1e-56 191.9 0.2 2e-56 191.0 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KLO17266.1 - 1e-21 77.1 0.1 3.6e-21 75.4 0.1 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KLO17266.1 - 2.8e-14 52.4 0.1 6.6e-14 51.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KLO17266.1 - 3e-11 42.8 0.0 6.3e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KLO17266.1 - 3.3e-11 42.9 0.1 7.8e-11 41.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KLO17266.1 - 2.4e-07 30.7 2.3 0.004 17.2 0.8 2.6 2 0 0 2 2 2 2 WW domain GTP_EFTU PF00009.27 KLO17267.1 - 6.1e-54 182.5 0.0 1e-53 181.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KLO17267.1 - 1.6e-15 56.9 0.0 4.7e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KLO17267.1 - 1.3e-08 35.1 0.0 3.4e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KLO17267.1 - 2.6e-06 27.4 0.0 6.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KLO17267.1 - 7.5e-05 22.5 0.0 0.0014 18.3 0.0 2.8 3 0 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KLO17267.1 - 0.001 19.1 0.0 0.0027 17.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KLO17267.1 - 0.058 12.5 0.0 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit cobW PF02492.19 KLO17268.1 - 3.5e-45 153.8 0.2 4.6e-45 153.4 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KLO17268.1 - 7.1e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 KLO17268.1 - 9.7e-05 22.0 0.2 0.028 14.0 0.1 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KLO17268.1 - 0.00051 19.1 0.2 0.32 9.9 0.0 3.0 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KLO17268.1 - 0.016 15.1 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 KLO17268.1 - 0.031 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KLO17268.1 - 0.032 14.5 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KLO17268.1 - 0.035 14.5 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KLO17268.1 - 0.039 14.0 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 KLO17268.1 - 0.04 13.4 0.1 4.1 6.8 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_29 PF13555.6 KLO17268.1 - 0.054 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KLO17268.1 - 0.1 13.1 0.0 0.34 11.5 0.1 1.9 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KLO17268.1 - 0.12 12.9 0.1 0.38 11.2 0.0 1.8 2 0 0 2 2 2 0 ABC transporter MobB PF03205.14 KLO17268.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 KLO17268.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KLO17268.1 - 0.18 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DSPc PF00782.20 KLO17269.1 - 3.7e-26 91.5 0.0 4.7e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KLO17269.1 - 0.0015 18.8 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain UAA PF08449.11 KLO17270.1 - 2.1e-39 135.5 11.5 5e-39 134.3 9.0 2.0 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.20 KLO17270.1 - 7.8e-11 42.3 19.7 2.3e-07 31.1 6.7 3.9 4 1 0 4 4 4 2 EamA-like transporter family TPT PF03151.16 KLO17270.1 - 0.00062 19.2 1.8 0.37 10.1 0.3 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 KLO17270.1 - 0.00099 18.4 3.3 0.067 12.3 0.3 2.4 2 0 0 2 2 2 2 Nucleotide-sugar transporter CRT-like PF08627.10 KLO17270.1 - 0.0038 16.2 5.4 0.24 10.3 0.5 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 KLO17270.1 - 0.1 12.6 2.6 2.1 8.4 0.3 2.7 2 0 0 2 2 2 0 Putative transmembrane family 234 NTP_transf_9 PF04248.12 KLO17271.1 - 5.4e-33 112.7 3.1 5.9e-33 112.6 3.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) IBR PF01485.21 KLO17272.1 - 1.4e-06 28.4 6.1 1.4e-06 28.4 6.1 3.9 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KLO17272.1 - 7e-06 26.3 8.5 7e-06 26.3 8.5 4.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KLO17272.1 - 5.4e-05 23.0 7.8 5.4e-05 23.0 7.8 4.7 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO17272.1 - 0.0015 18.4 8.0 0.0015 18.4 8.0 4.2 2 1 1 3 3 3 1 zinc-RING finger domain HALZ PF02183.18 KLO17272.1 - 0.005 17.0 2.9 0.016 15.4 1.6 2.2 2 0 0 2 2 2 1 Homeobox associated leucine zipper zf-RING_UBOX PF13445.6 KLO17272.1 - 0.016 15.2 6.7 0.016 15.2 6.7 3.8 3 1 0 3 3 3 0 RING-type zinc-finger zinc_ribbon_9 PF14369.6 KLO17272.1 - 0.13 12.5 21.6 0.28 11.5 2.7 4.9 4 1 0 4 4 4 0 zinc-ribbon zf-RING_11 PF17123.5 KLO17272.1 - 0.33 10.7 6.7 1.4 8.7 6.7 2.2 1 0 0 1 1 1 0 RING-like zinc finger Mito_carr PF00153.27 KLO17273.1 - 1.2e-72 239.9 0.2 1.1e-25 89.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4448 PF14610.6 KLO17274.1 - 0.0021 17.9 0.0 0.0067 16.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) MAP17 PF15807.5 KLO17274.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Retrotran_gag_2 PF14223.6 KLO17275.1 - 1.3e-08 34.6 0.0 1.4e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type CwfJ_C_2 PF04676.14 KLO17276.1 - 6.4e-35 120.0 0.0 2e-34 118.4 0.0 1.9 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KLO17276.1 - 8.1e-31 106.4 0.2 1.2e-30 105.9 0.2 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 HpcH_HpaI PF03328.14 KLO17277.1 - 9.8e-44 149.1 0.0 1.3e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KLO17277.1 - 8.8e-12 44.8 0.2 5.9e-06 25.7 0.0 2.2 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold E1_4HB PF16191.5 KLO17277.1 - 0.057 13.6 0.0 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle Get5_bdg PF16843.5 KLO17277.1 - 0.18 11.3 0.0 16 5.1 0.0 2.5 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein Rsa3 PF14615.6 KLO17278.1 - 2.7e-17 62.1 0.1 3.8e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 PNISR PF15996.5 KLO17278.1 - 0.23 11.7 8.0 0.35 11.1 8.0 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Macoilin PF09726.9 KLO17278.1 - 0.48 8.9 12.9 0.64 8.5 12.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF755 PF05501.11 KLO17278.1 - 2 8.7 33.0 3 8.2 12.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Spore_coat_CotO PF14153.6 KLO17278.1 - 3.4 7.6 8.0 5.3 6.9 8.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO SPX PF03105.19 KLO17278.1 - 4.1 7.2 21.1 4.9 7.0 21.1 1.2 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 KLO17278.1 - 4.2 6.0 9.2 4.2 6.0 9.2 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 KLO17278.1 - 4.3 4.3 15.6 5.5 4.0 15.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peroxin-3 PF04882.12 KLO17278.1 - 9.3 5.1 12.4 11 4.9 12.4 1.2 1 0 0 1 1 1 0 Peroxin-3 Helicase_C PF00271.31 KLO17279.1 - 7e-10 39.2 0.0 1e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peptidase_C97 PF05903.14 KLO17281.1 - 5.1e-42 143.3 0.0 8.4e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 KLO17281.1 - 1.2e-34 119.8 2.0 1.9e-34 119.2 2.0 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 KLO17281.1 - 1.3e-13 50.8 0.0 2.8e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KLO17281.1 - 0.00012 22.4 0.1 0.0018 18.7 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KLO17281.1 - 0.0021 17.5 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KLO17281.1 - 0.014 15.1 0.1 0.094 12.4 0.1 2.0 2 0 0 2 2 2 0 Redoxin AhpC-TSA PF00578.21 KLO17281.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family DSBA PF01323.20 KLO17281.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Ribosom_S12_S23 PF00164.25 KLO17282.1 - 9.2e-36 121.9 1.7 1.2e-35 121.6 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PH_4 PF15404.6 KLO17283.1 - 2.4e-19 69.8 1.9 3.3e-12 46.6 0.0 3.2 2 1 1 3 3 3 2 Pleckstrin homology domain AOX PF01786.17 KLO17284.1 - 1.9e-97 325.1 0.1 3e-97 324.4 0.1 1.3 1 0 0 1 1 1 1 Alternative oxidase Peptidase_S66C PF17676.1 KLO17284.1 - 0.11 13.0 0.1 0.44 11.1 0.0 2.1 2 0 0 2 2 2 0 LD-carboxypeptidase C-terminal domain Zn_clus PF00172.18 KLO17285.1 - 0.00029 20.9 12.1 0.00071 19.6 12.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carn_acyltransf PF00755.20 KLO17286.1 - 1.7e-190 634.5 0.0 2e-190 634.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase YqgC PF17430.2 KLO17287.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized YqgC-like Cut12 PF11500.8 KLO17289.1 - 0.19 11.7 1.7 0.41 10.6 1.7 1.5 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Nop25 PF09805.9 KLO17289.1 - 0.85 10.1 3.6 0.8 10.2 0.1 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Methyltransf_31 PF13847.6 KLO17290.1 - 4.2e-17 62.3 0.0 7.6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO17290.1 - 1.1e-15 58.0 0.0 3.5e-14 53.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO17290.1 - 3.4e-15 56.5 0.1 6.5e-14 52.4 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO17290.1 - 1.2e-11 44.7 0.0 2.9e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KLO17290.1 - 3.2e-11 43.4 0.0 5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KLO17290.1 - 6.9e-11 42.8 0.0 1.1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO17290.1 - 2.7e-10 40.0 0.0 2.1e-09 37.1 0.0 2.2 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KLO17290.1 - 5.7e-08 32.5 0.0 1.3e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KLO17290.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 KLO17290.1 - 1.2e-05 24.5 0.0 1.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) GCD14 PF08704.10 KLO17290.1 - 2.3e-05 24.2 0.0 3.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_32 PF13679.6 KLO17290.1 - 3.2e-05 24.0 0.0 8.7e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 KLO17290.1 - 0.00031 20.1 0.0 0.00043 19.6 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_7 PF03492.15 KLO17290.1 - 0.0024 17.1 0.0 5.9 6.0 0.0 3.1 3 0 0 3 3 3 1 SAM dependent carboxyl methyltransferase DOT1 PF08123.13 KLO17290.1 - 0.0043 16.6 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltr_RsmB-F PF01189.17 KLO17290.1 - 0.007 16.0 0.0 0.015 14.9 0.0 1.5 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 KLO17290.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KLO17290.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.12 KLO17290.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ADH_zinc_N PF00107.26 KLO17290.1 - 0.024 14.6 0.1 0.059 13.3 0.1 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase FtsJ PF01728.19 KLO17290.1 - 0.034 14.2 0.2 0.44 10.6 0.1 2.4 2 1 0 2 2 2 0 FtsJ-like methyltransferase FliG_C PF01706.16 KLO17290.1 - 0.039 14.1 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 FliG C-terminal domain DREV PF05219.12 KLO17290.1 - 0.045 12.8 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 DREV methyltransferase Fibrillarin PF01269.17 KLO17290.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin Methyltransf_4 PF02390.17 KLO17290.1 - 0.13 11.7 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase Pkinase PF00069.25 KLO17291.1 - 1.4e-09 37.7 0.0 5.6e-07 29.2 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO17291.1 - 0.0025 17.1 0.0 0.0053 16.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO17292.1 - 2.2e-27 96.1 0.0 1e-26 93.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO17292.1 - 2e-22 79.8 0.0 3.8e-22 78.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Dus PF01207.17 KLO17293.1 - 2.6e-55 187.7 0.0 4.5e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Torus PF16131.5 KLO17293.1 - 0.0011 19.7 2.1 0.13 13.0 0.1 2.4 2 0 0 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 KLO17293.1 - 0.0021 17.8 5.0 0.13 12.1 0.1 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Herpes_U44 PF04533.13 KLO17293.1 - 0.09 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Herpes virus U44 protein zf-CCCH PF00642.24 KLO17293.1 - 0.12 12.3 6.7 0.36 10.8 2.3 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KLO17293.1 - 0.95 9.6 6.3 17 5.7 0.2 2.6 2 0 0 2 2 2 0 Zinc finger domain Peptidase_M20 PF01546.28 KLO17294.1 - 3.3e-25 89.0 0.0 5.7e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KLO17294.1 - 4.7e-11 43.1 12.3 2.1e-05 25.2 0.2 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.14 KLO17294.1 - 6.5e-10 38.9 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain PepSY_2 PF13670.6 KLO17294.1 - 0.2 11.6 0.3 5.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain HA2 PF04408.23 KLO17295.1 - 7.5e-22 77.7 0.0 1.5e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KLO17295.1 - 3.3e-16 59.6 0.0 7e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KLO17295.1 - 2.7e-06 27.6 0.0 6.8e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KLO17295.1 - 4.4e-05 23.3 0.0 0.00021 21.1 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ABC_tran PF00005.27 KLO17295.1 - 0.00095 19.7 0.6 0.84 10.1 0.1 3.2 3 0 0 3 3 3 2 ABC transporter AAA_22 PF13401.6 KLO17295.1 - 0.0033 17.7 0.1 0.011 16.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KLO17295.1 - 0.12 11.5 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KLO17295.1 - 0.16 11.8 0.1 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase PF06745.13 KLO17295.1 - 0.17 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 KaiC RPAP3_C PF13877.6 KLO17296.1 - 6.1e-17 61.9 0.1 1.4e-16 60.8 0.0 1.6 2 0 0 2 2 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 KLO17296.1 - 6.7e-15 54.2 4.2 4.5e-05 23.1 0.2 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KLO17296.1 - 6e-14 51.0 3.3 3.2e-05 23.7 0.4 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KLO17296.1 - 5.9e-08 32.3 2.0 0.0023 17.6 0.2 2.4 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 KLO17296.1 - 8.5e-07 29.3 0.6 0.071 14.0 0.5 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KLO17296.1 - 2.1e-06 28.1 4.9 0.0086 16.6 0.3 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KLO17296.1 - 3.1e-06 27.0 1.7 0.0085 16.2 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KLO17296.1 - 6e-06 26.8 1.3 0.001 19.7 0.8 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KLO17296.1 - 1.1e-05 25.4 1.2 4.4e-05 23.5 0.2 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KLO17296.1 - 0.00011 22.4 2.0 0.025 14.9 1.3 2.8 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KLO17296.1 - 0.012 16.2 3.0 0.11 13.1 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KLO17296.1 - 0.027 14.5 0.3 3.6 7.8 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KLO17296.1 - 0.081 13.0 3.1 1.6 8.8 0.2 2.7 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 KLO17296.1 - 0.13 12.7 0.3 49 4.6 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KLO17296.1 - 1.2 9.1 3.1 11 6.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat HrpF PF06266.12 KLO17297.1 - 0.15 12.4 0.1 0.24 11.7 0.1 1.3 1 0 0 1 1 1 0 HrpF protein Dynein_heavy PF03028.15 KLO17298.1 - 0.12 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain DUF3245 PF11595.8 KLO17298.1 - 1.7 9.1 4.8 25 5.3 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) TPK_B1_binding PF04265.14 KLO17301.1 - 0.049 13.3 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain THOC7 PF05615.13 KLO17302.1 - 0.15 12.4 0.4 0.47 10.7 0.0 2.0 2 1 0 2 2 2 0 Tho complex subunit 7 THOC7 PF05615.13 KLO17303.1 - 0.077 13.3 0.0 0.085 13.1 0.0 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 DUF4203 PF13886.6 KLO17304.1 - 9.3e-09 35.2 13.6 2e-08 34.2 13.0 1.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4203) TFIIF_alpha PF05793.12 KLO17304.1 - 0.0056 15.3 2.2 0.0078 14.9 2.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2070 PF09843.9 KLO17304.1 - 6.4 4.9 9.0 9.5 4.4 9.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF373 PF04123.13 KLO17305.1 - 2.4 7.5 4.2 4.6 6.6 3.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) TMEM100 PF16311.5 KLO17305.1 - 2.7 7.6 4.8 0.5 10.0 0.5 1.9 2 0 0 2 2 2 0 Transmembrane protein 100 zf-Nse PF11789.8 KLO17306.1 - 1.9e-14 53.2 0.0 3.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KLO17306.1 - 0.0041 16.8 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Zn_ribbon_17 PF17120.5 KLO17306.1 - 0.0085 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KLO17306.1 - 0.049 13.5 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KLO17306.1 - 0.34 10.2 8.6 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger Presenilin PF01080.17 KLO17306.1 - 7.1 5.3 7.4 9.9 4.8 7.4 1.2 1 0 0 1 1 1 0 Presenilin GFA PF04828.14 KLO17307.1 - 3.9e-07 30.3 0.4 3.9e-07 30.3 0.4 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme p450 PF00067.22 KLO17308.1 - 1.3e-54 185.7 0.0 4.3e-54 184.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 ATP_bind_1 PF03029.17 KLO17310.1 - 0.054 13.3 0.1 0.059 13.1 0.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Homeobox_KN PF05920.11 KLO17311.1 - 6.7e-17 61.1 0.0 9.3e-17 60.7 0.0 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KLO17311.1 - 2.1e-05 24.3 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KLO17311.1 - 0.013 14.9 0.5 0.028 13.9 0.1 1.7 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez MGDG_synth PF06925.11 KLO17311.1 - 0.034 14.2 0.0 0.034 14.2 0.0 1.0 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase HTH_29 PF13551.6 KLO17311.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix LRR_4 PF12799.7 KLO17318.1 - 1.1e-25 89.2 36.9 6e-05 23.3 0.9 8.4 8 1 1 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KLO17318.1 - 2.1e-24 85.0 36.9 3.3e-07 30.0 2.5 5.7 5 0 0 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 KLO17318.1 - 8.3e-11 41.7 13.1 0.0038 16.8 0.1 5.5 4 1 1 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 KLO17318.1 - 0.97 10.2 28.4 8.6 7.3 0.2 8.9 8 2 0 8 8 8 0 Leucine Rich Repeat cobW PF02492.19 KLO17319.1 - 2.3e-31 108.8 0.0 2.8e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KLO17319.1 - 6.8e-05 22.0 0.5 0.0011 18.0 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KLO17319.1 - 0.012 15.7 0.0 0.027 14.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KLO17319.1 - 0.078 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KLO17319.1 - 0.078 13.5 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KLO17319.1 - 0.12 12.9 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.13 KLO17319.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 KLO17319.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KLO17319.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Imm51 PF15595.6 KLO17320.1 - 0.22 11.5 0.0 0.49 10.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 51 uDENN PF03456.18 KLO17321.1 - 1.2 9.9 5.2 0.22 12.3 0.9 2.0 2 0 0 2 2 2 0 uDENN domain TFIIA PF03153.13 KLO17321.1 - 3 7.7 12.8 3.5 7.5 12.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PBP PF01161.20 KLO17322.1 - 2.9e-13 50.3 0.0 4.6e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF4276 PF14103.6 KLO17322.1 - 0.042 14.1 0.0 0.23 11.6 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4276) PAC4 PF16093.5 KLO17322.1 - 0.047 13.9 0.0 0.18 12.0 0.0 2.1 1 1 0 1 1 1 0 Proteasome assembly chaperone 4 PBP PF01161.20 KLO17324.1 - 2.1e-10 41.0 0.1 3.4e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein KELK PF15796.5 KLO17328.1 - 0.015 15.7 0.9 0.015 15.7 0.9 4.5 3 2 2 5 5 5 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Oscp1 PF10188.9 KLO17328.1 - 0.053 13.6 0.3 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 Organic solute transport protein 1 DUF4611 PF15387.6 KLO17328.1 - 0.46 10.7 17.7 5.1 7.4 10.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 KLO17328.1 - 1.3 8.3 18.7 2.4 7.4 18.7 1.3 1 0 0 1 1 1 0 NOA36 protein BCDHK_Adom3 PF10436.9 KLO17328.1 - 1.7 8.5 5.3 1.6 8.6 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase 2OG-FeII_Oxy PF03171.20 KLO17329.1 - 0.064 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4218 PF13960.6 KLO17330.1 - 6.2e-06 25.8 0.0 1.3e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4218) LRR_10 PF18805.1 KLO17330.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat YibE_F PF07907.11 KLO17336.1 - 0.068 12.7 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 YibE/F-like protein Zn_clus PF00172.18 KLO17339.1 - 0.0098 16.0 11.4 0.018 15.1 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO17340.1 - 0.13 12.4 13.0 0.2 11.8 13.0 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Retrotran_gag_2 PF14223.6 KLO17341.1 - 3.4e-07 30.0 0.0 4.4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KLO17341.1 - 5e-05 23.2 0.6 7.9e-05 22.6 0.6 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 KLO17341.1 - 0.00022 20.9 1.0 0.00036 20.2 1.0 1.2 1 0 0 1 1 1 1 C2H2 zinc-finger PLAC8 PF04749.17 KLO17342.1 - 0.68 11.0 26.6 1.8 9.6 26.6 1.7 1 1 0 1 1 1 0 PLAC8 family DUF202 PF02656.15 KLO17343.1 - 1.6e-16 60.5 3.8 1.6e-16 60.5 3.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) IncE PF17627.2 KLO17343.1 - 0.077 13.0 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Inclusion membrane protein E CLLAC PF15675.5 KLO17343.1 - 1.5 8.5 8.9 3.5 7.2 8.9 1.6 1 0 0 1 1 1 0 CLLAC-motif containing domain DUF3357 PF11837.8 KLO17343.1 - 8.1 7.0 0.0 8.1 7.0 0.0 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF3357) YbgT_YccB PF08173.11 KLO17343.1 - 8.4 6.6 5.4 71 3.7 5.4 2.3 1 1 0 1 1 1 0 Membrane bound YbgT-like protein Hydrophobin PF01185.18 KLO17346.1 - 1e-14 54.9 4.2 1.2e-14 54.6 4.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CRAL_TRIO PF00650.20 KLO17347.1 - 1.1e-27 96.7 0.0 1.6e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KLO17347.1 - 3.2e-09 36.8 0.1 6.2e-08 32.7 0.0 2.6 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Abhydrolase_6 PF12697.7 KLO17348.1 - 4.3e-17 63.5 2.2 6e-17 63.0 2.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO17348.1 - 0.0069 15.7 0.5 0.014 14.6 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 RRM_1 PF00076.22 KLO17349.1 - 5e-07 29.4 0.0 1.2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KLO17349.1 - 2.4e-06 27.4 0.0 5.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KLO17349.1 - 5e-05 23.3 0.0 0.00015 21.8 0.0 1.8 1 0 0 1 1 1 1 RNA binding motif RRM_occluded PF16842.5 KLO17349.1 - 0.0079 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif DUF908 PF06012.12 KLO17349.1 - 0.06 12.7 0.6 0.077 12.4 0.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Mucin PF01456.17 KLO17349.1 - 0.47 10.4 7.7 0.83 9.6 7.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Hus1 PF04005.12 KLO17351.1 - 1.3e-70 237.8 0.0 1.5e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Rad1 PF02144.16 KLO17351.1 - 0.00048 19.3 0.1 0.0018 17.4 0.0 1.8 2 0 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Isochorismatase PF00857.20 KLO17352.1 - 7.8e-13 49.0 0.0 1.1e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Glutaredoxin PF00462.24 KLO17355.1 - 3.4e-19 68.8 0.0 3.1e-16 59.3 0.0 2.7 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 KLO17355.1 - 1.2e-12 47.8 0.0 2.3e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KLO17355.1 - 2.5e-05 24.5 0.0 0.003 17.9 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.6 KLO17355.1 - 0.00013 21.9 0.0 0.00041 20.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin domain HyaE PF07449.11 KLO17355.1 - 0.00024 21.0 0.0 0.0032 17.4 0.0 2.4 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KLO17355.1 - 0.0035 17.2 0.2 0.014 15.2 0.0 1.9 2 1 1 3 3 3 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KLO17355.1 - 0.0049 17.3 0.0 0.027 14.9 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain DUF1631 PF07793.11 KLO17355.1 - 0.031 12.7 0.4 0.04 12.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Ku PF02735.16 KLO17356.1 - 1.9e-36 125.7 0.0 8.5e-36 123.6 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KLO17356.1 - 1.5e-21 77.2 0.0 2.3e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KLO17356.1 - 1.3e-13 51.4 0.1 3.4e-13 50.1 0.1 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KLO17356.1 - 2.7e-08 33.4 0.1 4.9e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.6 KLO17356.1 - 0.024 15.3 0.0 0.077 13.6 0.0 1.9 1 0 0 1 1 1 0 von Willebrand factor type A domain HeH PF12949.7 KLO17356.1 - 0.27 11.0 0.9 0.79 9.5 0.1 2.2 2 1 0 2 2 2 0 HeH/LEM domain Cupin_1 PF00190.22 KLO17357.1 - 6.3e-39 133.0 0.0 8.9e-20 70.8 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KLO17357.1 - 2.6e-26 91.1 0.3 4e-12 45.7 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KLO17357.1 - 4e-06 26.4 0.1 0.14 11.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KLO17357.1 - 7.5e-06 25.9 0.2 0.0033 17.3 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KLO17357.1 - 0.00088 19.2 0.0 0.0047 16.8 0.0 1.9 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase GPI PF06560.11 KLO17357.1 - 0.047 13.0 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) DUF1971 PF09313.11 KLO17357.1 - 0.083 12.9 0.0 0.67 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) Cupin_1 PF00190.22 KLO17358.1 - 2.5e-38 131.0 0.1 8.2e-18 64.5 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KLO17358.1 - 7e-26 89.8 0.4 7.7e-12 44.8 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KLO17358.1 - 2.3e-07 30.4 0.1 0.0062 16.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KLO17358.1 - 0.00014 21.8 0.3 0.028 14.3 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KLO17358.1 - 0.00068 19.5 0.0 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_4 PF08007.12 KLO17358.1 - 0.074 12.5 0.1 3 7.2 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein UCH PF00443.29 KLO17359.1 - 4.3e-53 180.4 1.6 5.7e-53 180.0 1.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KLO17359.1 - 2.2e-22 80.1 7.7 6.9e-22 78.5 7.7 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KLO17359.1 - 9.5e-12 45.1 8.3 9.5e-12 45.1 8.3 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein NOC3p PF07540.11 KLO17359.1 - 0.095 13.2 0.5 0.22 12.0 0.5 1.5 1 0 0 1 1 1 0 Nucleolar complex-associated protein SCP2 PF02036.17 KLO17360.1 - 9e-27 93.5 1.7 1.1e-26 93.2 1.7 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KLO17360.1 - 8.2e-06 26.1 0.9 1.1e-05 25.7 0.9 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Big_6 PF17936.1 KLO17360.1 - 0.012 15.8 0.2 0.027 14.7 0.2 1.6 1 1 1 2 2 2 0 Bacterial Ig domain DUF3287 PF11690.8 KLO17360.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Dynamin_N PF00350.23 KLO17361.1 - 3.4e-43 147.6 0.0 6.9e-43 146.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KLO17361.1 - 7.4e-14 51.6 0.0 1.8e-13 50.4 0.0 1.7 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KLO17361.1 - 5.9e-05 23.1 0.0 0.0002 21.4 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KLO17361.1 - 0.028 14.2 0.0 0.076 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KLO17361.1 - 0.071 13.6 0.0 0.34 11.4 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 KLO17361.1 - 0.098 13.1 0.4 26 5.2 0.0 3.1 3 1 0 3 3 3 0 AAA domain Roc PF08477.13 KLO17361.1 - 0.11 12.7 0.1 0.89 9.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RTP PF02334.16 KLO17361.1 - 0.13 12.9 0.4 0.34 11.6 0.1 1.8 2 0 0 2 2 2 0 Replication terminator protein AAA_15 PF13175.6 KLO17361.1 - 0.15 11.7 0.1 0.15 11.7 0.1 2.3 3 0 0 3 3 3 0 AAA ATPase domain PTPA PF03095.15 KLO17362.1 - 3.6e-94 315.6 0.0 4.3e-94 315.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF2517 PF10725.9 KLO17363.1 - 0.051 13.3 0.2 0.093 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) Orn_Arg_deC_N PF02784.16 KLO17364.1 - 8e-76 254.7 0.0 1e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KLO17364.1 - 1.4e-16 60.5 0.0 1.6e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain B12-binding PF02310.19 KLO17364.1 - 0.02 14.9 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain KilA-N PF04383.13 KLO17365.1 - 0.00086 19.1 0.1 0.34 10.8 0.0 2.2 2 0 0 2 2 2 2 KilA-N domain Na_sulph_symp PF00939.19 KLO17367.1 - 1.9e-27 96.4 19.6 3.9e-27 95.4 19.6 1.6 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 KLO17367.1 - 7.5e-24 85.4 8.0 1.2e-14 55.1 1.1 2.5 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 KLO17367.1 - 2.8e-19 69.4 16.4 2.8e-19 69.4 16.4 2.0 2 1 1 3 3 3 2 Citrate transporter SAM_2 PF07647.17 KLO17368.1 - 0.058 13.5 0.1 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) UPF0086 PF01868.16 KLO17369.1 - 8.2e-32 109.0 0.0 3.4e-31 107.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function UPF0086 DUF4553 PF15090.6 KLO17369.1 - 0.038 13.0 3.1 0.056 12.4 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) ADH_zinc_N PF00107.26 KLO17370.1 - 2e-17 63.4 0.1 5.1e-17 62.1 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO17370.1 - 2.1e-17 63.0 0.5 4.8e-17 61.8 0.5 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DHDPS PF00701.22 KLO17371.1 - 2.1e-37 128.4 0.0 2.6e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Med22 PF06179.12 KLO17372.1 - 2.6e-20 72.6 0.7 3.7e-20 72.1 0.7 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PMC2NT PF08066.12 KLO17372.1 - 0.043 14.5 2.0 2 9.2 1.3 2.2 1 1 1 2 2 2 0 PMC2NT (NUC016) domain SIMPL PF04402.14 KLO17372.1 - 0.93 9.9 5.0 1.5 9.3 5.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Ribosomal_S13 PF00416.22 KLO17373.1 - 1.8e-53 180.3 2.6 2.1e-53 180.1 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 KLO17373.1 - 0.0068 16.8 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2746) FbpA PF05833.11 KLO17373.1 - 0.019 13.7 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KLO17373.1 - 0.063 13.5 0.2 0.17 12.1 0.1 1.9 2 1 0 2 2 2 0 Helix-hairpin-helix motif BET PF17035.5 KLO17373.1 - 0.091 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation ADH_N PF08240.12 KLO17374.1 - 4.5e-23 81.2 7.7 8.4e-23 80.3 7.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO17374.1 - 1.7e-14 53.9 0.1 3.3e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KLO17374.1 - 3e-05 23.5 0.2 6.9e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KLO17374.1 - 0.00046 19.6 0.0 0.0009 18.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain zf-CCCH PF00642.24 KLO17375.1 - 6.4e-19 67.4 24.3 2.4e-05 24.1 0.6 4.5 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KLO17375.1 - 4.6e-13 48.7 29.2 1.2e-06 28.3 2.1 4.8 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 KLO17375.1 - 8.2e-08 32.9 16.9 0.00035 21.2 0.2 4.3 1 1 3 4 4 4 3 Torus domain zf-CCCH_4 PF18044.1 KLO17375.1 - 2.9e-05 23.7 0.4 2.9e-05 23.7 0.4 4.5 4 0 0 4 4 4 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KLO17375.1 - 5.4e-05 23.5 26.3 0.0039 17.6 0.2 5.1 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-CCHC PF00098.23 KLO17375.1 - 0.00059 19.8 3.5 0.0023 17.9 3.5 2.1 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KLO17375.1 - 0.0096 15.9 0.1 0.026 14.5 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle F-box_5 PF18511.1 KLO17375.1 - 0.011 15.2 0.3 0.02 14.5 0.3 1.3 1 0 0 1 1 1 0 F-box zf-CCHC_2 PF13696.6 KLO17375.1 - 0.029 14.2 2.6 0.14 12.0 2.6 2.3 1 0 0 1 1 1 0 Zinc knuckle TMEM247 PF15444.6 KLO17376.1 - 3.1 7.8 4.3 2.3 8.2 3.2 1.3 1 1 0 1 1 1 0 Transmembrane protein 247 Thg1 PF04446.12 KLO17377.1 - 1.1e-47 161.1 0.0 1.8e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KLO17377.1 - 2.4e-44 150.4 0.2 3.3e-44 149.9 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain COPIIcoated_ERV PF07970.12 KLO17378.1 - 1.7e-37 129.5 0.2 2.4e-37 128.9 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KLO17378.1 - 2.8e-21 75.6 0.0 5e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-C3HC4 PF00097.25 KLO17379.1 - 1e-08 34.9 4.7 1.9e-08 34.0 4.7 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO17379.1 - 1.1e-07 31.6 11.5 5e-07 29.5 11.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO17379.1 - 4.6e-07 29.7 6.6 1.1e-06 28.6 5.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KLO17379.1 - 3.2e-06 26.9 7.2 7.9e-05 22.4 4.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO17379.1 - 3.9e-06 26.7 9.4 9.7e-06 25.5 9.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KLO17379.1 - 7.1e-06 26.3 10.4 1.3e-05 25.4 10.4 1.4 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KLO17379.1 - 3.9e-05 23.4 10.1 0.00046 20.0 10.1 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KLO17379.1 - 0.0036 17.4 9.4 0.009 16.1 4.6 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF1644 PF07800.12 KLO17379.1 - 0.068 13.2 7.9 0.72 9.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) Pellino PF04710.14 KLO17379.1 - 0.6 8.7 1.8 0.83 8.3 1.8 1.2 1 0 0 1 1 1 0 Pellino zf-RING_10 PF16685.5 KLO17379.1 - 2.8 8.2 9.9 45 4.3 9.9 2.1 1 1 0 1 1 1 0 zinc RING finger of MSL2 Maf PF02545.14 KLO17380.1 - 5.5e-44 149.9 0.0 6.4e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein MutS_I PF01624.20 KLO17380.1 - 0.059 13.6 0.0 3.2 8.0 0.0 2.3 2 0 0 2 2 2 0 MutS domain I DnaJ PF00226.31 KLO17381.1 - 5e-20 71.4 2.2 8.7e-20 70.6 0.3 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 KLO17381.1 - 1.6e-13 49.8 0.1 0.00036 20.2 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KLO17381.1 - 2e-12 46.2 11.5 0.035 14.2 0.1 7.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KLO17381.1 - 8.6e-12 45.5 16.1 2.3e-06 28.2 0.1 6.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KLO17381.1 - 1.9e-10 41.1 8.0 0.041 14.4 0.0 6.3 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KLO17381.1 - 6.5e-09 36.0 4.0 0.0071 16.6 0.1 5.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KLO17381.1 - 6.1e-08 32.8 9.7 7.6 7.4 0.0 7.1 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 KLO17381.1 - 4.1e-07 30.0 12.7 0.26 11.5 0.1 5.6 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KLO17381.1 - 4.9e-06 26.1 4.7 0.00014 21.5 0.7 3.9 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 KLO17381.1 - 4.9e-05 23.2 7.3 0.098 12.9 0.1 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KLO17381.1 - 0.00026 21.5 14.0 0.81 10.7 0.0 6.4 6 2 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KLO17381.1 - 0.00029 21.0 0.3 0.062 13.7 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KLO17381.1 - 0.00044 20.1 4.8 0.66 10.1 0.0 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat ANAPC5 PF12862.7 KLO17381.1 - 0.00097 19.2 5.4 1.1 9.4 0.0 4.9 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 5 ANAPC3 PF12895.7 KLO17381.1 - 0.021 15.0 10.4 0.73 10.1 0.1 5.3 4 3 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 KLO17381.1 - 0.036 14.5 0.0 0.036 14.5 0.0 3.6 3 1 0 3 3 3 0 Bacterial transcriptional activator domain Phage_lysozyme2 PF18013.1 KLO17381.1 - 0.16 12.0 0.1 0.16 12.0 0.1 2.3 3 0 0 3 3 3 0 Phage tail lysozyme TIP49 PF06068.13 KLO17382.1 - 2.2e-157 523.8 0.1 2.6e-157 523.5 0.1 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KLO17382.1 - 4.7e-20 71.5 0.0 1.1e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KLO17382.1 - 1.4e-09 38.5 0.1 3.8e-06 27.3 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KLO17382.1 - 3.6e-09 36.5 0.0 1.8e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KLO17382.1 - 1.2e-05 25.6 0.1 0.2 12.0 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KLO17382.1 - 5.3e-05 23.2 0.1 0.034 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KLO17382.1 - 0.00019 21.9 0.1 0.0015 18.9 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KLO17382.1 - 0.0018 17.9 0.0 0.0045 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KLO17382.1 - 0.002 18.3 0.0 0.28 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KLO17382.1 - 0.0031 17.8 0.1 0.0092 16.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO17382.1 - 0.0057 17.0 1.2 0.12 12.7 1.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KLO17382.1 - 0.0071 16.9 0.0 0.067 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 KLO17382.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 KLO17382.1 - 0.017 14.4 0.2 0.1 11.8 0.1 2.0 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 KLO17382.1 - 0.033 13.9 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KLO17382.1 - 0.041 13.6 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KLO17382.1 - 0.055 12.8 0.1 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KLO17382.1 - 0.072 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KLO17382.1 - 0.14 12.2 0.0 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.17 KLO17382.1 - 0.18 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MBOAT PF03062.19 KLO17383.1 - 2e-46 159.0 24.1 3.1e-46 158.3 24.1 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Aminotran_1_2 PF00155.21 KLO17384.1 - 2.9e-35 122.1 0.0 4.2e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II PutA_N PF18083.1 KLO17384.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Proline utilization A N-terminal domain RNase_P_Rpp14 PF01900.19 KLO17385.1 - 1.9e-28 98.7 0.0 2.4e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family SPA PF08616.10 KLO17387.1 - 1.5e-05 24.9 0.1 2.9e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis BORG_CEP PF14957.6 KLO17387.1 - 0.006 17.7 0.0 0.012 16.8 0.0 1.4 1 0 0 1 1 1 1 Cdc42 effector CK_II_beta PF01214.18 KLO17388.1 - 1.3e-79 266.2 0.0 1.6e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF4139 PF13598.6 KLO17389.1 - 3.5e-35 121.6 0.0 1.3e-34 119.7 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KLO17389.1 - 1.5e-13 51.0 1.3 1.5e-12 47.7 1.3 2.5 1 1 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.6 KLO17389.1 - 0.001 19.8 24.2 0.001 19.8 24.2 2.9 2 1 1 3 3 3 2 Nucleoporin FG repeat region Rabaptin PF03528.15 KLO17389.1 - 0.051 12.3 0.3 0.075 11.7 0.3 1.1 1 0 0 1 1 1 0 Rabaptin FAD_binding_1 PF00667.20 KLO17390.1 - 2.3e-38 132.0 0.0 3.2e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KLO17390.1 - 1e-27 97.1 0.0 1.9e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KLO17390.1 - 4.7e-09 36.9 0.0 1.5e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain HTH_43 PF09904.9 KLO17390.1 - 0.11 12.5 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix Peptidase_M48 PF01435.18 KLO17391.1 - 1.6e-19 70.4 0.0 7.1e-19 68.4 0.0 2.0 2 1 0 2 2 2 1 Peptidase family M48 AA_permease_2 PF13520.6 KLO17392.1 - 1.2e-67 228.7 35.5 1.5e-67 228.3 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KLO17392.1 - 1.8e-17 63.1 33.7 2.5e-17 62.7 33.7 1.1 1 0 0 1 1 1 1 Amino acid permease AGTRAP PF06396.11 KLO17392.1 - 9.7 6.0 10.9 0.42 10.4 2.3 2.6 3 0 0 3 3 3 0 Angiotensin II, type I receptor-associated protein (AGTRAP) 3D PF06725.11 KLO17393.1 - 0.023 14.9 0.7 12 6.2 0.1 2.9 2 0 0 2 2 2 0 3D domain CoA_transf_3 PF02515.17 KLO17395.1 - 1.9e-59 201.7 0.0 2.8e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Polysacc_deac_1 PF01522.21 KLO17396.1 - 6.1e-28 97.2 0.0 1.3e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase COX5B PF01215.19 KLO17397.1 - 1.1e-44 151.2 0.0 1.4e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C2H2_3 PF13878.6 KLO17397.1 - 0.0009 19.0 0.3 0.0018 18.1 0.3 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO PMI_typeI PF01238.21 KLO17398.1 - 2e-111 372.8 0.0 2.3e-111 372.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KLO17398.1 - 7.1e-05 22.4 0.2 0.12 12.1 0.1 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KLO17398.1 - 0.038 13.9 0.0 4.8 7.1 0.0 2.7 3 0 0 3 3 3 0 AraC-like ligand binding domain Cupin_6 PF12852.7 KLO17398.1 - 0.14 11.9 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Cupin UPF0061 PF02696.14 KLO17399.1 - 2.2e-101 340.0 0.0 6.8e-101 338.3 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Transglut_i_TM PF14400.6 KLO17400.1 - 0.00023 21.3 1.2 0.00026 21.1 0.3 1.6 2 1 0 2 2 2 1 Inactive transglutaminase fused to 7 transmembrane helices Chorion_2 PF03964.15 KLO17400.1 - 0.046 14.6 0.4 0.046 14.6 0.4 1.9 1 1 1 2 2 2 0 Chorion family 2 LAMTOR5 PF16672.5 KLO17400.1 - 0.094 12.7 1.0 0.22 11.5 0.1 1.9 2 1 0 2 2 2 0 Ragulator complex protein LAMTOR5 NADH-u_ox-rdase PF10785.9 KLO17401.1 - 0.5 11.1 4.0 0.7 10.6 0.3 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit AMP-binding PF00501.28 KLO17402.1 - 1.5e-75 254.4 0.0 1.9e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KLO17402.1 - 7e-06 26.9 0.0 5.6e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain UPF0242 PF06785.11 KLO17403.1 - 0.0016 18.6 2.6 0.0018 18.4 0.2 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 KLO17403.1 - 0.0028 17.8 2.6 0.0097 16.1 2.6 2.0 1 0 0 1 1 1 1 Haemolysin XhlA Tup_N PF08581.10 KLO17403.1 - 0.022 15.0 7.7 0.022 15.0 7.7 2.6 2 1 1 3 3 2 0 Tup N-terminal DUF724 PF05266.14 KLO17403.1 - 0.07 13.0 6.0 0.19 11.5 6.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 KLO17403.1 - 0.08 10.8 3.1 0.096 10.6 3.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIN_8 PF18476.1 KLO17403.1 - 0.51 10.1 7.7 1.4 8.8 7.7 1.7 1 0 0 1 1 1 0 PIN like domain Csm1_N PF18504.1 KLO17403.1 - 0.63 10.4 14.2 0.19 12.1 2.8 3.7 3 1 1 4 4 3 0 Csm1 N-terminal domain DUF1192 PF06698.11 KLO17403.1 - 0.69 10.0 11.2 1.7 8.7 1.5 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF1192) HeLo PF14479.6 KLO17403.1 - 0.78 9.5 7.4 0.07 13.0 2.1 2.0 2 0 0 2 2 2 0 Prion-inhibition and propagation TPR_MLP1_2 PF07926.12 KLO17403.1 - 0.8 9.8 12.6 1.2 9.3 10.2 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Peptidase_S46 PF10459.9 KLO17403.1 - 0.88 8.1 11.2 0.08 11.6 6.7 1.5 2 0 0 2 2 2 0 Peptidase S46 DUF4407 PF14362.6 KLO17403.1 - 1.1 8.6 7.0 2.1 7.6 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Filament PF00038.21 KLO17403.1 - 1.5 8.3 17.2 18 4.8 14.8 2.8 2 1 0 2 2 2 0 Intermediate filament protein PKcGMP_CC PF16808.5 KLO17403.1 - 2.1 8.3 7.7 0.37 10.7 0.4 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BLOC1_2 PF10046.9 KLO17403.1 - 3 8.2 7.8 0.48 10.8 1.1 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 KLO17403.1 - 3.8 6.0 6.1 1.1 7.8 3.2 1.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A TMPIT PF07851.13 KLO17403.1 - 5.1 6.2 4.9 9.4 5.4 4.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 KLO17403.1 - 5.8 6.8 8.1 5 7.0 2.7 3.2 2 1 1 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.8 KLO17403.1 - 5.8 7.0 12.5 35 4.5 0.2 3.8 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Bac_luciferase PF00296.20 KLO17403.1 - 6.9 6.0 7.3 1 8.7 3.1 1.7 2 0 0 2 2 2 0 Luciferase-like monooxygenase dCache_2 PF08269.11 KLO17403.1 - 9.8 5.2 7.9 16 4.6 6.3 1.9 2 0 0 2 2 2 0 Cache domain Metallophos PF00149.28 KLO17405.1 - 1.8e-35 123.3 0.4 2.9e-35 122.6 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KLO17405.1 - 0.003 18.0 0.1 0.0065 16.9 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain cwf21 PF08312.12 KLO17405.1 - 4.8 7.4 5.0 1.3 9.3 1.8 1.7 2 0 0 2 2 2 0 cwf21 domain Cpn60_TCP1 PF00118.24 KLO17406.1 - 2.4e-154 514.6 1.3 2.7e-154 514.5 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Swi5 PF07061.11 KLO17407.1 - 0.48 10.6 3.3 1.8 8.7 3.3 2.0 1 0 0 1 1 1 0 Swi5 Sad1_UNC PF07738.13 KLO17409.1 - 1e-24 87.0 0.0 7.6e-12 45.4 0.0 2.6 1 1 0 2 2 2 2 Sad1 / UNC-like C-terminal CBX7_C PF17218.3 KLO17409.1 - 0.06 13.1 0.4 0.13 12.0 0.4 1.5 1 0 0 1 1 1 0 CBX family C-terminal motif Abhydrolase_1 PF00561.20 KLO17410.1 - 1.7e-37 129.5 0.0 2.5e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO17410.1 - 1.7e-11 43.8 0.0 5.4e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KLO17410.1 - 4.9e-11 43.7 0.0 6.5e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KLO17410.1 - 0.00076 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 KLO17410.1 - 0.0025 17.3 0.0 0.97 8.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KLO17410.1 - 0.0063 16.1 0.1 0.012 15.2 0.1 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.14 KLO17410.1 - 0.011 14.4 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family HECT PF00632.25 KLO17411.1 - 2.3e-95 319.6 0.0 2.9e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KLO17411.1 - 1.5e-37 127.3 19.7 2.7e-13 49.7 5.1 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KLO17411.1 - 9.6e-22 77.2 0.3 2.7e-21 75.8 0.2 1.9 1 1 0 1 1 1 1 C2 domain RRM_1 PF00076.22 KLO17412.1 - 1.2e-13 50.6 0.0 2.4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4692 PF15763.5 KLO17412.1 - 0.072 13.6 0.4 0.2 12.1 0.4 1.7 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Nup35_RRM_2 PF14605.6 KLO17412.1 - 0.074 13.1 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KLO17412.1 - 0.14 12.4 1.6 0.34 11.1 0.0 2.4 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter SNAPc19 PF15497.6 KLO17412.1 - 0.25 11.8 4.2 0.3 11.6 1.3 2.2 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 CRAL_TRIO PF00650.20 KLO17413.1 - 1.9e-27 95.9 0.0 3.1e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KLO17413.1 - 1.9e-17 63.1 0.2 3.5e-17 62.3 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KLO17413.1 - 0.00071 19.7 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MFS_1 PF07690.16 KLO17415.1 - 3.9e-26 91.8 73.5 4.9e-22 78.3 44.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3980 PF13140.6 KLO17415.1 - 0.058 13.8 2.8 0.21 12.0 2.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3980) AAA PF00004.29 KLO17416.1 - 1.6e-41 141.8 0.0 2.7e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KLO17416.1 - 1.5e-11 44.1 0.1 2.9e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KLO17416.1 - 1.3e-09 37.7 0.4 2.5e-09 36.8 0.4 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KLO17416.1 - 2.1e-06 27.9 0.1 5.8e-06 26.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KLO17416.1 - 3.1e-05 23.3 0.0 5.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KLO17416.1 - 4.6e-05 23.7 0.2 0.03 14.6 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 KLO17416.1 - 0.0003 21.2 0.2 0.0091 16.4 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KLO17416.1 - 0.00041 20.4 0.2 0.0027 17.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KLO17416.1 - 0.0006 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 KLO17416.1 - 0.002 17.5 0.4 0.15 11.4 0.1 2.8 2 1 1 3 3 3 1 KaiC AAA_3 PF07726.11 KLO17416.1 - 0.0055 16.6 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 KLO17416.1 - 0.006 16.2 0.3 0.022 14.4 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 KLO17416.1 - 0.0073 16.9 0.1 0.023 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KLO17416.1 - 0.0073 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KLO17416.1 - 0.017 15.2 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KLO17416.1 - 0.034 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KLO17416.1 - 0.045 13.0 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 KLO17416.1 - 0.056 13.4 0.1 0.8 9.6 0.1 2.5 2 1 1 3 3 3 0 NACHT domain AAA_28 PF13521.6 KLO17416.1 - 0.067 13.4 0.1 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KLO17416.1 - 0.11 12.3 0.3 0.35 10.6 0.2 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KLO17416.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KLO17416.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KLO17416.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KLO17416.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KLO17416.1 - 0.32 10.6 0.9 4.6 6.8 0.2 2.5 1 1 1 2 2 2 0 AAA domain Med26 PF08711.11 KLO17417.1 - 9.7e-09 35.1 0.0 9.7e-09 35.1 0.0 2.8 4 0 0 4 4 4 1 TFIIS helical bundle-like domain GIT1_C PF12205.8 KLO17417.1 - 0.069 13.3 0.1 0.2 11.8 0.1 1.8 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Mito_carr PF00153.27 KLO17420.1 - 3.1e-57 190.5 4.1 7e-22 77.2 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_16 PF10294.9 KLO17421.1 - 8.4e-23 81.0 0.0 6.1e-18 65.2 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Arrestin_N PF00339.29 KLO17422.1 - 2.6e-06 27.5 0.0 1.4e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.29 KLO17423.1 - 6.5e-10 39.2 0.0 4.5e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KLO17423.1 - 0.0081 16.6 0.0 0.023 15.1 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain TNFR_16_TM PF18422.1 KLO17424.1 - 0.077 13.0 1.3 0.13 12.3 1.3 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Arrestin_N PF00339.29 KLO17425.1 - 1.6e-07 31.5 0.0 6.9e-05 22.9 0.0 3.2 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KLO17425.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Arrestin_N terminal like Arrestin_N PF00339.29 KLO17426.1 - 2.3e-09 37.5 0.1 7e-06 26.2 0.0 2.8 2 2 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain G-alpha PF00503.20 KLO17427.1 - 5.6e-121 404.0 0.0 6.4e-121 403.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO17427.1 - 4.8e-13 48.9 0.0 1.1e-09 38.1 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KLO17427.1 - 0.00092 19.4 0.0 2.2 8.5 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KLO17427.1 - 0.0012 18.5 0.1 0.14 11.7 0.0 2.7 3 0 0 3 3 3 1 Ras family AAA_24 PF13479.6 KLO17427.1 - 0.0062 16.3 0.1 0.77 9.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain TniB PF05621.11 KLO17427.1 - 0.027 13.9 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein Gtr1_RagA PF04670.12 KLO17427.1 - 0.13 11.6 0.3 2.3 7.5 0.0 2.6 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KLO17427.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pro_isomerase PF00160.21 KLO17428.1 - 1.4e-46 158.7 0.0 1.6e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sld7_N PF18636.1 KLO17428.1 - 0.062 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain F_actin_cap_B PF01115.17 KLO17429.1 - 9.2e-105 349.5 0.0 1.1e-104 349.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Arrestin_N PF00339.29 KLO17430.1 - 1.1e-09 38.5 0.7 1.4e-08 34.9 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Gtr1_RagA PF04670.12 KLO17431.1 - 9.3e-39 133.1 0.0 1.4e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KLO17431.1 - 1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KLO17431.1 - 3.2e-05 23.5 0.0 5.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KLO17431.1 - 0.00013 22.2 0.0 0.00042 20.5 0.0 1.9 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KLO17431.1 - 0.0086 16.1 0.0 0.019 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain Ndc1_Nup PF09531.10 KLO17431.1 - 0.049 12.3 5.7 0.073 11.8 5.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ras PF00071.22 KLO17431.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Ras family TFIIA PF03153.13 KLO17431.1 - 1.3 8.9 7.4 0.45 10.5 4.6 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 KLO17431.1 - 9.6 6.0 14.8 3.7 7.4 12.0 1.7 2 0 0 2 2 2 0 SPX domain VTC PF09359.10 KLO17432.1 - 4.3e-101 337.9 0.2 5e-100 334.4 0.0 2.4 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 KLO17432.1 - 6.2e-14 52.7 33.9 7.4e-07 29.4 0.3 4.4 2 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 KLO17432.1 - 8.1e-11 42.2 1.0 1.8e-10 41.1 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Phage_Arf PF17585.2 KLO17432.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Accessory recombination function protein Herpes_UL25 PF01499.16 KLO17432.1 - 0.32 9.5 4.6 0.14 10.6 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus UL25 family DBR1 PF05011.13 KLO17432.1 - 0.45 10.9 5.1 0.82 10.1 0.0 3.5 4 0 0 4 4 4 0 Lariat debranching enzyme, C-terminal domain FliE PF02049.18 KLO17432.1 - 3.2 7.9 9.1 0.57 10.4 0.2 2.8 3 0 0 3 3 3 0 Flagellar hook-basal body complex protein FliE VSP PF03302.13 KLO17433.1 - 2.5e-08 33.2 14.2 3.4e-08 32.8 14.2 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Apt1 PF10351.9 KLO17433.1 - 0.067 12.0 9.2 0.088 11.6 9.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mucin15 PF15672.5 KLO17433.1 - 0.13 11.7 25.9 0.2 11.1 25.9 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 SPX PF03105.19 KLO17433.1 - 0.23 11.3 8.7 0.29 11.0 8.7 1.3 1 0 0 1 1 1 0 SPX domain DUF4551 PF15087.6 KLO17433.1 - 0.85 8.4 6.1 1.1 8.0 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CPSF100_C PF13299.6 KLO17433.1 - 1.7 8.8 3.7 2.6 8.2 3.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Utp14 PF04615.13 KLO17433.1 - 5.6 5.4 6.4 7.4 5.0 6.4 1.0 1 0 0 1 1 1 0 Utp14 protein Plasmodium_Vir PF05795.11 KLO17433.1 - 7.4 5.9 6.7 12 5.1 6.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF5521 PF17659.1 KLO17433.1 - 7.9 4.2 11.6 11 3.8 11.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DUF863 PF05904.11 KLO17433.1 - 9.7 4.5 17.4 13 4.1 17.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) PTPlike_phytase PF14566.6 KLO17434.1 - 1.3e-136 451.0 0.0 8.4e-46 155.9 0.0 3.6 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase PF00102.27 KLO17434.1 - 9.3e-05 22.1 0.0 0.13 11.8 0.0 3.3 3 0 0 3 3 3 1 Protein-tyrosine phosphatase DSPc PF00782.20 KLO17434.1 - 0.00021 21.1 0.0 0.63 9.9 0.0 3.7 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain SPATA24 PF15175.6 KLO17434.1 - 0.13 12.1 0.4 0.36 10.7 0.2 1.8 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 THUMP PF02926.17 KLO17435.1 - 2.7e-08 34.0 0.8 7.3e-08 32.6 0.1 1.9 2 0 0 2 2 2 1 THUMP domain Cwf_Cwc_15 PF04889.12 KLO17435.1 - 0.018 14.8 1.1 0.025 14.3 1.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyco_trans_1_3 PF13528.6 KLO17436.1 - 0.0021 17.4 0.0 0.0053 16.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 1 Ldh_1_N PF00056.23 KLO17436.1 - 0.018 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain p450 PF00067.22 KLO17437.1 - 6.5e-59 199.9 0.0 7.7e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GCP_C_terminal PF04130.13 KLO17438.1 - 2.4e-50 171.8 0.1 4.3e-50 170.9 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal RicinB_lectin_2 PF14200.6 KLO17439.1 - 0.05 14.3 0.2 0.93 10.3 0.1 2.4 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like p450 PF00067.22 KLO17440.1 - 4.3e-62 210.4 0.0 5.6e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO17442.1 - 7.8e-66 222.7 0.0 9.7e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DSPc PF00782.20 KLO17443.1 - 1.5e-23 83.0 0.0 6.6e-21 74.5 0.0 3.0 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KLO17443.1 - 0.031 13.8 0.1 0.057 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KLO17443.1 - 0.052 13.8 0.0 0.86 9.9 0.0 2.3 2 0 0 2 2 2 0 Rit1 DUSP-like domain Lar_restr_allev PF14354.6 KLO17443.1 - 0.19 12.2 0.4 0.54 10.7 0.2 1.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar ABC2_membrane PF01061.24 KLO17444.1 - 8.8e-33 113.5 19.4 8.8e-33 113.5 19.4 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KLO17444.1 - 2.6e-25 89.5 0.1 6.7e-25 88.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KLO17444.1 - 0.00014 21.8 0.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KLO17444.1 - 0.013 15.4 0.2 0.04 13.8 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase ABC2_membrane_3 PF12698.7 KLO17444.1 - 0.015 14.4 22.3 0.0092 15.1 19.7 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein AAA_16 PF13191.6 KLO17444.1 - 0.042 14.2 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KLO17444.1 - 0.065 13.0 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KLO17444.1 - 0.2 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain hEGF PF12661.7 KLO17444.1 - 9.4 7.0 21.8 6.1 7.6 8.9 4.2 3 0 0 3 3 3 0 Human growth factor-like EGF Epimerase PF01370.21 KLO17445.1 - 4.3e-22 78.8 0.0 5.4e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO17445.1 - 4.6e-12 46.0 0.0 3.3e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KLO17445.1 - 5.6e-12 45.9 0.0 7e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KLO17445.1 - 1.2e-09 37.6 0.0 1.5e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KLO17445.1 - 5e-06 26.8 0.0 7.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 KLO17445.1 - 1.7e-05 24.4 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KLO17445.1 - 0.00014 21.2 0.0 0.0011 18.2 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KLO17445.1 - 0.00015 21.4 0.0 0.0002 21.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KLO17445.1 - 0.0011 18.1 0.0 0.0028 16.8 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short_C2 PF13561.6 KLO17445.1 - 0.0055 16.3 0.1 0.0091 15.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DapB_N PF01113.20 KLO17445.1 - 0.029 14.5 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KLO17445.1 - 0.032 14.5 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LRR_4 PF12799.7 KLO17447.1 - 0.061 13.8 4.2 11 6.7 0.1 3.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO17448.1 - 7.9e-08 32.1 1.5 2.2e-07 30.6 1.5 1.9 1 0 0 1 1 1 1 F-box-like RC-P840_PscD PF10657.9 KLO17448.1 - 0.0069 16.5 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Photosystem P840 reaction centre protein PscD F-box PF00646.33 KLO17448.1 - 0.026 14.4 3.6 0.71 9.8 3.6 3.0 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KLO17449.1 - 1.8e-06 27.7 0.5 1.3e-05 25.0 0.3 2.6 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO17450.1 - 0.00065 19.5 0.1 0.0017 18.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO17450.1 - 0.067 13.6 8.2 51 4.5 0.2 5.2 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO17451.1 - 9.8e-06 25.4 0.2 4e-05 23.4 0.2 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO17452.1 - 0.00017 21.4 1.6 0.00035 20.4 0.4 2.2 2 0 0 2 2 2 1 F-box-like zf-RVT PF13966.6 KLO17453.1 - 6.3e-05 23.6 0.2 0.00014 22.5 0.2 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 KLO17453.1 - 0.0034 17.6 0.1 0.0059 16.8 0.1 1.3 1 0 0 1 1 1 1 RNase H zf-CCHC_6 PF15288.6 KLO17455.1 - 0.0028 17.4 0.6 0.0088 15.9 0.6 1.8 1 0 0 1 1 1 1 Zinc knuckle CcmH PF03918.14 KLO17455.1 - 0.0096 15.2 1.1 0.94 8.8 0.2 3.3 3 0 0 3 3 3 1 Cytochrome C biogenesis protein Peptidase_M29 PF02073.15 KLO17455.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Copper-fist PF00649.18 KLO17455.1 - 6 6.4 9.2 0.35 10.4 2.7 2.3 1 1 2 3 3 3 0 Copper fist DNA binding domain F-box-like PF12937.7 KLO17457.1 - 0.00018 21.3 0.1 0.00047 20.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO17458.1 - 7.7e-05 22.5 0.4 0.00028 20.7 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO17458.1 - 0.63 10.0 6.0 0.25 11.3 2.5 2.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO17459.1 - 8e-05 22.5 0.4 0.00019 21.2 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO17460.1 - 0.0028 17.5 2.0 0.0028 17.5 2.0 2.9 3 1 0 3 3 3 1 F-box-like F-box-like PF12937.7 KLO17464.1 - 4.7e-06 26.4 6.4 1.2e-05 25.1 6.4 1.7 1 1 0 1 1 1 1 F-box-like PRY PF13765.6 KLO17464.1 - 0.12 12.1 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 SPRY-associated domain F-box-like PF12937.7 KLO17465.1 - 0.00028 20.7 3.6 0.00042 20.1 0.4 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO17467.1 - 0.02 14.8 7.0 0.16 11.9 7.0 2.5 1 1 0 1 1 1 0 F-box-like PMT PF02366.18 KLO17468.1 - 6.3e-81 271.6 13.9 6.3e-81 271.6 13.9 1.8 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KLO17468.1 - 8.5e-66 221.3 11.6 8.5e-66 221.3 11.6 2.2 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KLO17468.1 - 3e-39 134.8 1.1 4.4e-39 134.3 0.5 1.6 2 0 0 2 2 2 1 MIR domain DUF1240 PF06836.12 KLO17468.1 - 0.064 13.8 0.1 3.8 8.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) Mito_carr PF00153.27 KLO17469.1 - 2.7e-54 181.1 0.5 3.7e-20 71.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.24 KLO17470.1 - 5.3e-44 150.0 3.0 7.5e-44 149.6 3.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KLO17470.1 - 1.6e-29 102.9 0.9 2.6e-28 98.9 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KLO17470.1 - 2.7e-22 79.5 1.6 4.4e-22 78.8 1.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KLO17470.1 - 7.3e-21 74.2 0.0 1.6e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 KLO17470.1 - 0.024 15.2 0.0 0.057 14.0 0.0 1.8 1 1 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal BTB PF00651.31 KLO17471.1 - 0.0061 16.8 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Arf PF00025.21 KLO17472.1 - 6.7e-68 227.6 0.1 7.6e-68 227.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KLO17472.1 - 1.3e-13 50.9 0.7 2.4e-08 33.5 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KLO17472.1 - 3.6e-10 39.6 0.0 4.5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KLO17472.1 - 4e-10 39.9 0.0 6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KLO17472.1 - 1.1e-09 38.1 0.0 1.4e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KLO17472.1 - 2.2e-09 37.0 0.0 3e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KLO17472.1 - 1.5e-07 31.5 0.0 2.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KLO17472.1 - 0.00031 20.3 0.0 0.0037 16.8 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KLO17472.1 - 0.029 13.9 0.1 0.52 9.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KLO17472.1 - 0.042 13.9 0.1 0.1 12.6 0.1 1.6 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 KLO17472.1 - 0.044 13.7 0.1 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 KLO17472.1 - 0.069 13.4 0.0 0.18 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KLO17472.1 - 0.077 12.5 0.3 0.16 11.5 0.3 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 KLO17472.1 - 0.14 12.7 0.0 0.23 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KLO17473.1 - 6.5e-33 113.9 0.0 4.7e-32 111.1 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KLO17473.1 - 6.3e-18 64.8 0.3 6e-17 61.7 0.0 2.5 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KLO17473.1 - 1.3e-13 51.1 6.4 6e-10 39.4 0.1 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KLO17473.1 - 6.1e-08 32.7 1.6 2.7e-07 30.7 0.0 3.0 4 0 0 4 4 4 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KLO17473.1 - 1.2e-05 25.1 2.2 1.4e-05 24.9 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Cwf_Cwc_15 PF04889.12 KLO17473.1 - 0.00083 19.2 16.0 0.00083 19.2 16.0 5.5 2 1 2 5 5 5 1 Cwf15/Cwc15 cell cycle control protein Roc PF08477.13 KLO17473.1 - 0.016 15.4 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase eIF2A PF08662.11 KLO17476.1 - 0.063 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KLO17476.1 - 0.13 13.1 0.0 17 6.5 0.0 2.9 2 1 0 2 2 2 0 WD domain, G-beta repeat dUTPase PF00692.19 KLO17480.1 - 8.3e-43 145.2 0.0 9.6e-43 145.0 0.0 1.0 1 0 0 1 1 1 1 dUTPase Nif11 PF07862.11 KLO17482.1 - 0.066 13.5 0.4 2.5 8.5 0.0 2.7 2 0 0 2 2 2 0 Nif11 domain AC_N PF16214.5 KLO17482.1 - 0.095 11.8 0.3 0.14 11.3 0.3 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF730 PF05325.11 KLO17482.1 - 0.17 11.9 0.1 0.4 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF730) p450 PF00067.22 KLO17485.1 - 4.3e-57 193.9 0.0 6.3e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Spt4 PF06093.13 KLO17486.1 - 1.7e-29 101.7 0.4 2.1e-29 101.4 0.4 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DUF411 PF04214.13 KLO17486.1 - 0.14 12.1 0.2 21 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF TAFII55_N PF04658.13 KLO17487.1 - 5.2e-58 195.3 0.9 5.2e-58 195.3 0.9 2.0 2 1 0 2 2 2 1 TAFII55 protein conserved region BUD22 PF09073.10 KLO17487.1 - 1.8e-05 24.3 14.0 1.8e-05 24.3 14.0 2.4 1 1 1 3 3 3 1 BUD22 D123 PF07065.14 KLO17487.1 - 3 6.9 9.1 5.6 6.0 9.1 1.6 1 1 0 1 1 1 0 D123 Cpn60_TCP1 PF00118.24 KLO17488.1 - 3e-144 481.3 11.1 3.4e-144 481.1 11.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KLO17488.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat UPRTase PF14681.6 KLO17489.1 - 1.3e-76 256.7 0.0 1.6e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KLO17489.1 - 1.4e-05 24.7 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Cyclin_N PF00134.23 KLO17490.1 - 1.4e-10 41.0 0.9 5.7e-09 35.8 0.2 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KLO17490.1 - 0.00022 21.3 0.6 0.0056 16.8 0.1 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 KLO17490.1 - 0.017 15.2 0.8 0.95 9.6 0.1 2.7 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 KLO17490.1 - 0.092 13.1 0.2 0.45 10.9 0.1 2.4 2 1 0 2 2 2 0 Cyclin C-terminal domain p450 PF00067.22 KLO17491.1 - 5.6e-54 183.6 0.0 8.3e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glycos_trans_3N PF02885.17 KLO17491.1 - 0.17 11.8 0.1 0.43 10.5 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Peptidase_S28 PF05577.12 KLO17492.1 - 1.5e-47 162.4 3.0 3.7e-47 161.1 3.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KLO17492.1 - 1.8e-05 24.4 0.0 8.8e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KLO17492.1 - 8.9e-05 21.9 0.0 0.00034 19.9 0.0 1.8 1 1 0 2 2 2 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 KLO17492.1 - 0.0015 17.8 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 KLO17492.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO17492.1 - 0.076 13.6 0.0 0.17 12.5 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 KLO17492.1 - 0.088 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KLO17492.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold S36_mt PF10937.8 KLO17493.1 - 9.5e-10 40.1 5.4 1.9e-07 32.7 5.4 2.0 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial ODV-E18 PF10717.9 KLO17493.1 - 0.2 11.6 0.1 0.26 11.2 0.1 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Proteasome PF00227.26 KLO17494.1 - 3.3e-46 157.2 0.0 7.8e-46 156.0 0.0 1.5 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KLO17494.1 - 6.9e-15 54.4 0.6 1.9e-14 53.0 0.3 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Tho1_MOS11_C PF18592.1 KLO17494.1 - 0.0073 16.1 0.5 0.015 15.1 0.3 1.6 1 1 0 1 1 1 1 Tho1/MOS11 C-terminal domain 7TMR-HDED PF07697.11 KLO17494.1 - 0.075 13.1 0.1 0.099 12.8 0.1 1.1 1 0 0 1 1 1 0 7TM-HD extracellular RNA_pol_Rpb1_1 PF04997.12 KLO17495.1 - 4e-86 289.2 0.0 6.2e-86 288.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KLO17495.1 - 2e-84 283.2 0.3 3e-84 282.6 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KLO17495.1 - 2.5e-73 245.8 0.0 4.4e-73 245.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KLO17495.1 - 2.7e-39 134.6 0.0 8.1e-39 133.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KLO17495.1 - 1e-31 109.1 0.0 2.5e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 IRF PF00605.17 KLO17495.1 - 0.018 15.3 0.1 0.039 14.2 0.1 1.5 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor Viral_Beta_CD PF04530.12 KLO17496.1 - 0.016 15.5 0.4 0.044 14.1 0.2 1.8 1 1 0 1 1 1 0 Viral Beta C/D like family G_glu_transpept PF01019.21 KLO17497.1 - 5.3e-165 550.0 0.0 6.1e-165 549.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase UPF0242 PF06785.11 KLO17498.1 - 0.014 15.5 11.7 0.032 14.3 11.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 KLO17498.1 - 0.034 14.7 17.2 0.067 13.7 17.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Fmp27_WPPW PF10359.9 KLO17498.1 - 0.065 12.1 8.8 0.088 11.7 8.8 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Exonuc_VII_L PF02601.15 KLO17498.1 - 0.13 11.9 5.2 0.15 11.6 5.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM184 PF15665.5 KLO17498.1 - 0.18 11.6 14.0 0.3 10.8 14.0 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_Mu_Gam PF07352.12 KLO17498.1 - 0.27 11.1 8.4 0.52 10.2 8.4 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein GIT_CC PF16559.5 KLO17498.1 - 0.29 11.0 5.8 0.88 9.5 3.3 2.5 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 KLO17498.1 - 0.36 11.0 9.0 0.81 9.9 9.0 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 YabA PF06156.13 KLO17498.1 - 0.58 10.8 11.9 0.28 11.8 5.0 2.4 1 1 1 2 2 2 0 Initiation control protein YabA AATF-Che1 PF13339.6 KLO17498.1 - 0.89 10.2 15.2 0.097 13.4 9.7 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Mto2_bdg PF12808.7 KLO17498.1 - 0.96 9.8 12.9 0.84 10.0 2.7 2.8 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region V_ATPase_I PF01496.19 KLO17498.1 - 1 7.2 8.1 1.3 6.9 8.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Jnk-SapK_ap_N PF09744.9 KLO17498.1 - 1.2 9.3 15.5 2.7 8.2 15.5 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Tho2 PF11262.8 KLO17498.1 - 1.3 8.2 11.2 1.6 7.8 9.2 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 LMBR1 PF04791.16 KLO17498.1 - 1.5 7.6 4.2 1.8 7.4 4.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DBINO PF13892.6 KLO17498.1 - 1.6 9.1 16.1 0.24 11.8 12.1 1.8 2 0 0 2 2 1 0 DNA-binding domain Fez1 PF06818.15 KLO17498.1 - 1.9 8.9 19.8 2.5 8.5 3.0 2.4 1 1 1 2 2 2 0 Fez1 DUF763 PF05559.11 KLO17498.1 - 1.9 7.6 5.9 0.77 8.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF763) LCD1 PF09798.9 KLO17498.1 - 4.9 5.6 8.5 6.1 5.2 8.5 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF5595 PF18077.1 KLO17498.1 - 5.4 7.2 7.8 18 5.5 3.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) GDI PF00996.18 KLO17500.1 - 4.6e-43 147.3 0.0 6.1e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Med13_C PF06333.12 KLO17501.1 - 6.5e-29 101.2 4.5 6.5e-29 101.2 4.5 3.0 2 1 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KLO17501.1 - 2.1e-26 93.1 0.6 4.4e-26 92.0 0.6 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KLO17501.1 - 5.6e-05 23.1 0.1 0.00021 21.2 0.0 1.9 2 1 0 3 3 3 1 MID domain of medPIWI MerR PF00376.23 KLO17501.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein DUF2433 PF10360.9 KLO17502.1 - 1.6e-44 150.9 0.0 3.1e-44 150.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 KLO17502.1 - 0.0013 18.6 0.1 0.0025 17.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 KLO17502.1 - 0.034 14.6 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase DUF2478 PF10649.9 KLO17502.1 - 0.11 12.1 0.1 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) Spem1 PF15670.5 KLO17503.1 - 5.1 6.6 10.0 5.9 6.4 10.0 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 RRM_1 PF00076.22 KLO17504.1 - 3.3e-45 151.8 0.0 2.1e-23 81.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KLO17504.1 - 1.7e-07 31.2 0.0 0.0014 18.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KLO17504.1 - 0.00016 21.6 0.0 0.44 10.6 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KLO17504.1 - 0.00047 19.8 0.0 0.00083 19.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KLO17504.1 - 0.013 15.3 0.0 0.38 10.6 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KLO17504.1 - 0.078 13.0 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif DUF898 PF05987.13 KLO17505.1 - 0.088 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Kinesin_assoc PF16183.5 KLO17506.1 - 0.014 15.5 0.8 0.014 15.5 0.8 1.9 2 1 0 2 2 2 0 Kinesin-associated SIKE PF05769.11 KLO17506.1 - 0.018 15.0 6.5 0.043 13.8 0.7 2.4 2 0 0 2 2 2 0 SIKE family Tektin PF03148.14 KLO17506.1 - 0.027 13.2 7.4 0.021 13.6 2.7 2.1 2 0 0 2 2 2 0 Tektin family Lebercilin PF15619.6 KLO17506.1 - 0.034 13.8 12.0 0.083 12.5 6.8 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TMCO5 PF14992.6 KLO17506.1 - 0.047 13.3 2.4 0.069 12.7 2.4 1.3 1 0 0 1 1 1 0 TMCO5 family SlyX PF04102.12 KLO17506.1 - 0.079 13.6 15.0 0.52 11.0 1.3 4.3 2 1 2 4 4 4 0 SlyX ABC_tran_CTD PF16326.5 KLO17506.1 - 0.081 13.2 7.5 1.2 9.5 2.2 3.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain Fez1 PF06818.15 KLO17506.1 - 0.084 13.3 5.9 0.15 12.5 5.9 1.4 1 0 0 1 1 1 0 Fez1 DUF641 PF04859.12 KLO17506.1 - 0.088 13.2 5.6 1.7 9.0 0.7 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Vir_act_alpha_C PF10400.9 KLO17506.1 - 0.2 12.4 4.6 0.41 11.4 0.1 2.6 2 1 0 2 2 2 0 Virulence activator alpha C-term Transcrip_act PF04949.13 KLO17506.1 - 0.35 10.7 6.5 0.63 9.9 0.1 2.8 2 1 1 3 3 3 0 Transcriptional activator FlaC_arch PF05377.11 KLO17506.1 - 0.5 10.8 5.7 1.2 9.6 0.2 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 KLO17506.1 - 0.52 10.3 9.6 9.6 6.3 0.2 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 KLO17506.1 - 0.7 9.9 11.0 1 9.3 4.5 2.7 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 KLO17506.1 - 0.7 9.7 4.5 1.1 9.1 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.9 KLO17506.1 - 0.72 10.1 11.2 8.8 6.5 0.1 2.6 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 OmpH PF03938.14 KLO17506.1 - 0.73 10.2 6.4 1.5 9.1 0.8 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 KLO17506.1 - 0.74 10.0 5.4 1.8 8.8 1.8 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Rho_Binding PF08912.11 KLO17506.1 - 0.93 10.4 6.8 5.4 7.9 0.1 3.0 3 0 0 3 3 2 0 Rho Binding Cep57_MT_bd PF06657.13 KLO17506.1 - 0.98 9.9 8.7 5.8 7.4 0.1 3.2 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Prefoldin PF02996.17 KLO17506.1 - 1 9.3 5.0 4.4 7.3 0.3 2.7 3 0 0 3 3 2 0 Prefoldin subunit GAS PF13851.6 KLO17506.1 - 1.2 8.5 11.6 3.7 6.9 0.4 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 KLO17506.1 - 1.4 9.4 6.0 2.9 8.4 1.6 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 UPF0242 PF06785.11 KLO17506.1 - 1.7 8.7 14.0 3.3 7.8 6.2 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 KLO17506.1 - 2.6 7.9 13.4 0.87 9.4 0.4 3.4 3 1 1 4 4 4 0 Septum formation initiator CENP-Q PF13094.6 KLO17506.1 - 3.8 7.7 15.0 0.92 9.7 10.8 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Swi5 PF07061.11 KLO17506.1 - 3.9 7.6 7.0 3.7 7.7 0.1 2.7 2 0 0 2 2 2 0 Swi5 Cep57_CLD_2 PF14197.6 KLO17506.1 - 4 7.6 14.1 9.4 6.4 3.3 3.4 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 KLO17506.1 - 5.3 5.8 14.3 7.3 5.4 8.5 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein GvpL_GvpF PF06386.11 KLO17506.1 - 6.3 6.7 8.2 4.4 7.2 4.7 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF ACCA PF03255.14 KLO17506.1 - 9.5 6.1 6.9 13 5.6 4.0 2.4 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PSD5 PF07637.11 KLO17507.1 - 0.1 13.0 0.7 2.1 8.7 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1595) Cass2 PF14526.6 KLO17507.1 - 0.16 12.1 0.1 0.23 11.6 0.1 1.2 1 0 0 1 1 1 0 Integron-associated effector binding protein Actin PF00022.19 KLO17508.1 - 1.3e-146 488.3 0.0 4.6e-146 486.6 0.0 1.7 1 1 0 1 1 1 1 Actin GerD PF17898.1 KLO17508.1 - 0.052 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Spore germination GerD central core domain CGI-121 PF08617.10 KLO17509.1 - 1.2e-51 175.1 2.0 1.3e-51 174.9 2.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Thioredoxin PF00085.20 KLO17510.1 - 1.9e-53 178.8 0.1 2.3e-26 91.7 0.0 3.5 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KLO17510.1 - 1.4e-17 64.2 0.0 3.8e-09 36.7 0.0 3.9 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KLO17510.1 - 3.3e-06 27.5 0.1 0.32 11.5 0.0 3.5 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KLO17510.1 - 4.7e-05 23.6 0.0 3.7 7.9 0.0 3.9 3 1 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 KLO17510.1 - 4.8e-05 22.9 0.0 0.056 12.8 0.0 3.3 2 2 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KLO17510.1 - 0.0056 16.7 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.6 KLO17510.1 - 0.066 13.4 2.1 0.13 12.4 0.2 2.3 2 1 0 2 2 2 0 Thioredoxin Terminase_GpA PF05876.12 KLO17510.1 - 0.28 9.7 3.1 0.16 10.5 0.2 1.8 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) PPR_2 PF13041.6 KLO17511.1 - 4.1e-49 164.6 14.3 2.1e-13 50.3 0.1 14.4 10 3 7 17 17 17 10 PPR repeat family PPR PF01535.20 KLO17511.1 - 4.6e-40 133.1 11.4 4.6e-06 26.5 0.0 14.6 16 1 0 16 16 16 7 PPR repeat PPR_3 PF13812.6 KLO17511.1 - 4.3e-34 116.4 0.9 1.1e-08 35.0 0.0 10.3 8 2 2 10 10 10 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 KLO17511.1 - 2.5e-27 94.3 1.2 3.8e-05 23.3 0.0 11.8 13 0 0 13 13 13 5 PPR repeat PPR_long PF17177.4 KLO17511.1 - 1.3e-19 70.4 3.4 1.2e-11 44.4 0.1 5.0 4 2 1 6 6 6 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KLO17511.1 - 7.9e-05 23.2 12.0 14 6.8 0.0 9.8 12 1 0 12 12 12 1 Tetratricopeptide repeat RPM2 PF08579.11 KLO17511.1 - 0.11 12.9 0.4 9.9 6.6 0.0 3.9 4 0 0 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) Med10 PF09748.9 KLO17512.1 - 4.7e-22 78.2 0.1 7.1e-22 77.6 0.1 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIN_4 PF13638.6 KLO17512.1 - 0.0059 16.9 0.0 0.0075 16.6 0.0 1.2 1 0 0 1 1 1 1 PIN domain KIAA1430 PF13879.6 KLO17512.1 - 0.039 14.7 0.5 0.056 14.2 0.5 1.3 1 0 0 1 1 1 0 KIAA1430 homologue Oxidored_FMN PF00724.20 KLO17513.1 - 3.6e-90 302.7 0.0 4.1e-90 302.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FA_desaturase PF00487.24 KLO17514.1 - 1.8e-17 64.0 26.3 3.7e-17 63.0 26.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KLO17514.1 - 3e-13 49.7 0.0 5.3e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Chitin_synth_2 PF03142.15 KLO17514.1 - 0.099 11.2 0.1 0.15 10.7 0.1 1.1 1 0 0 1 1 1 0 Chitin synthase CMAS PF02353.20 KLO17515.1 - 4.2e-57 193.5 0.0 5.6e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KLO17515.1 - 1.1e-09 38.8 0.0 3.2e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO17515.1 - 2.7e-07 31.2 0.0 5.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO17515.1 - 2.4e-05 24.3 0.0 3.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO17515.1 - 0.0016 18.2 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain SAC3 PF12209.8 KLO17515.1 - 0.0075 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Leucine permease transcriptional regulator helical domain Methyltransf_12 PF08242.12 KLO17515.1 - 0.017 15.9 0.0 0.037 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KLO17515.1 - 0.033 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.14 KLO17515.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.13 KLO17515.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_24 PF13578.6 KLO17515.1 - 0.13 13.3 0.1 2 9.5 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain Ank_2 PF12796.7 KLO17516.1 - 1.9e-17 63.6 0.0 8.7e-09 35.8 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KLO17516.1 - 4.7e-15 55.3 0.3 6.1e-06 26.5 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KLO17516.1 - 5.4e-15 55.6 0.0 4.1e-09 36.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KLO17516.1 - 1.5e-12 47.5 0.0 0.0001 22.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KLO17516.1 - 1.6e-10 40.3 0.2 0.0079 16.6 0.0 4.5 5 1 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.13 KLO17516.1 - 0.0038 17.1 0.1 0.09 12.6 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain KxDL PF10241.9 KLO17516.1 - 0.01 16.1 1.2 0.027 14.7 1.2 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein Acyl-CoA_dh_C PF12806.7 KLO17516.1 - 0.098 12.8 1.0 1.3 9.2 0.0 2.6 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like TMF_TATA_bd PF12325.8 KLO17516.1 - 0.55 10.5 9.2 1.7 8.9 5.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DSPn PF14671.6 KLO17517.1 - 7.9e-42 143.0 0.0 3.5e-40 137.7 0.0 2.5 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KLO17517.1 - 2.6e-14 53.1 0.0 4.8e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KLO17517.1 - 5.8e-05 22.8 0.0 0.00015 21.5 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KLO17517.1 - 0.0005 20.2 0.0 0.00095 19.3 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KLO17517.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family URO-D PF01208.17 KLO17518.1 - 2.3e-131 438.1 0.0 2.6e-131 437.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) COMPASS-Shg1 PF05205.12 KLO17519.1 - 5.3e-10 39.9 0.0 8.7e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 FAD_binding_3 PF01494.19 KLO17521.1 - 1.4e-66 225.1 0.0 1.9e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KLO17521.1 - 0.00052 19.7 0.5 0.089 12.4 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO17521.1 - 0.0011 18.3 0.2 0.0034 16.7 0.1 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KLO17521.1 - 0.02 15.3 0.0 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding PGA_cap PF09587.10 KLO17521.1 - 0.049 13.1 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap TrkA_N PF02254.18 KLO17521.1 - 0.067 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 KLO17521.1 - 0.095 13.3 0.0 9 7.0 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KLO17521.1 - 0.11 12.2 0.1 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Kinesin PF00225.23 KLO17522.1 - 1.2e-107 359.7 0.0 2.7e-107 358.6 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.8 KLO17522.1 - 4.3e-44 150.9 0.1 1.4e-43 149.2 0.1 2.0 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KLO17522.1 - 7.9e-40 136.9 6.6 5.4e-31 108.1 2.8 3.0 1 1 1 2 2 2 2 Kinesin-associated Microtub_bd PF16796.5 KLO17522.1 - 2.1e-20 73.2 0.0 5.9e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 KLO17522.1 - 7.3e-11 42.5 0.0 2.1e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 PH domain FHA PF00498.26 KLO17522.1 - 2.1e-05 24.8 0.0 8.9e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 KLO17522.1 - 0.00065 20.1 2.6 0.0017 18.8 0.1 3.1 4 0 0 4 4 3 1 Kinesin protein 1B PilJ PF13675.6 KLO17522.1 - 0.013 15.5 5.1 0.04 13.9 0.4 3.5 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term LMBR1 PF04791.16 KLO17522.1 - 0.18 10.7 4.1 5.6 5.7 1.9 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein EPOP PF15223.6 KLO17522.1 - 0.35 10.2 6.4 0.72 9.2 6.4 1.5 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein UPF0242 PF06785.11 KLO17522.1 - 0.41 10.7 19.3 1.5 8.9 8.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 KLO17522.1 - 4 7.6 18.1 0.98 9.6 4.5 2.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FAD_binding_3 PF01494.19 KLO17523.1 - 1.9e-41 142.5 0.4 1.3e-32 113.5 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain Acyl-CoA_dh_1 PF00441.24 KLO17523.1 - 2e-30 106.0 2.3 2.3e-30 105.8 0.9 1.9 2 0 0 2 2 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KLO17523.1 - 9.1e-15 54.7 0.5 2.5e-14 53.2 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KLO17523.1 - 1.3e-11 45.2 0.0 2.5e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 KLO17523.1 - 1.3e-11 44.4 0.0 3.5e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_2 PF07992.14 KLO17523.1 - 9.3e-05 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO17523.1 - 0.0015 17.8 0.0 0.0036 16.6 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Acyl-CoA_dh_2 PF08028.11 KLO17523.1 - 0.0021 18.4 0.2 0.0048 17.2 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DAO PF01266.24 KLO17523.1 - 0.0041 16.7 0.1 0.032 13.8 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KLO17523.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KLO17523.1 - 0.077 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KLO17523.1 - 0.092 13.0 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KLO17523.1 - 0.11 11.1 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein TetR_C_6 PF13977.6 KLO17523.1 - 0.13 12.5 0.2 29 4.9 0.1 2.6 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Orf78 PF06024.12 KLO17524.1 - 0.087 13.1 0.1 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) DUF1180 PF06679.12 KLO17524.1 - 7.7 6.9 11.7 0.54 10.7 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Mucin-like PF16058.5 KLO17525.1 - 0.011 15.8 3.2 0.014 15.5 3.2 1.1 1 0 0 1 1 1 0 Mucin-like Orf78 PF06024.12 KLO17528.1 - 0.14 12.4 0.1 1 9.7 0.0 2.1 2 0 0 2 2 2 0 Orf78 (ac78) DUF1180 PF06679.12 KLO17528.1 - 0.41 11.0 7.0 0.53 10.7 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TMEM154 PF15102.6 KLO17528.1 - 0.53 10.2 2.7 0.99 9.3 0.2 2.3 3 0 0 3 3 3 0 TMEM154 protein family GET2 PF08690.10 KLO17530.1 - 3.9e-08 33.3 0.0 8.3e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 GET complex subunit GET2 L51_S25_CI-B8 PF05047.16 KLO17531.1 - 8.8e-06 25.6 0.1 5e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MRP_L53 PF10780.9 KLO17531.1 - 0.014 15.5 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 YL1 PF05764.13 KLO17532.1 - 1.4e-32 113.7 24.5 1.8e-32 113.4 24.5 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 KLO17532.1 - 5.5e-11 42.0 0.1 9.2e-11 41.3 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF2207 PF09972.9 KLO17533.1 - 0.097 11.4 1.6 0.47 9.1 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) NicO PF03824.16 KLO17533.1 - 0.14 11.5 1.8 0.51 9.6 0.0 2.2 2 0 0 2 2 2 0 High-affinity nickel-transport protein DUF4181 PF13789.6 KLO17533.1 - 0.21 11.8 0.0 0.21 11.8 0.0 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4181) DUF2956 PF11169.8 KLO17533.1 - 1.7 8.8 7.4 14 5.9 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) adh_short PF00106.25 KLO17534.1 - 2.2e-32 112.1 0.0 1.6e-31 109.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO17534.1 - 1.5e-24 86.9 0.0 1.2e-15 57.7 0.0 2.9 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO17534.1 - 0.0012 18.7 0.2 0.0022 18.0 0.2 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KLO17534.1 - 0.072 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MutS_V PF00488.21 KLO17535.1 - 3.1e-56 190.4 0.1 5.8e-56 189.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KLO17535.1 - 1.8e-32 113.1 2.3 1.8e-32 113.1 2.3 2.3 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KLO17535.1 - 7.2e-07 29.5 0.2 2.4e-06 27.8 0.2 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KLO17535.1 - 0.0049 17.1 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 MutS domain II Amidase PF01425.21 KLO17536.1 - 3.6e-104 349.2 0.0 4.2e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 Amidase DAO PF01266.24 KLO17537.1 - 9.5e-34 117.5 0.6 2.2e-33 116.3 0.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KLO17537.1 - 0.00019 20.7 0.0 0.00039 19.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KLO17537.1 - 0.00036 20.7 0.0 0.00098 19.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO17537.1 - 0.00038 19.8 0.0 0.00053 19.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KLO17537.1 - 0.024 14.6 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KLO17537.1 - 0.025 13.8 0.5 0.039 13.2 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 KLO17537.1 - 0.038 13.1 0.1 0.056 12.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KLO17537.1 - 0.086 11.9 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.6 KLO17537.1 - 0.089 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4889 PF16230.5 KLO17539.1 - 0.034 14.4 0.1 0.089 13.0 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4889) SH3_1 PF00018.28 KLO17539.1 - 0.051 13.2 0.1 0.096 12.3 0.1 1.4 1 0 0 1 1 1 0 SH3 domain zf-UBR PF02207.20 KLO17541.1 - 9e-16 57.8 21.0 9e-16 57.8 21.0 3.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KLO17541.1 - 4.6e-11 42.4 0.0 1.6e-10 40.6 0.0 2.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS tRNA_U5-meth_tr PF05958.11 KLO17542.1 - 4.4e-18 65.4 0.0 5.2e-17 61.9 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KLO17542.1 - 6.2e-06 25.9 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KLO17542.1 - 1.7e-05 25.4 0.0 3.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO17542.1 - 0.00054 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KLO17542.1 - 0.0012 18.6 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KLO17542.1 - 0.0042 17.7 0.0 0.011 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO17542.1 - 0.0047 16.5 0.0 0.0074 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KLO17542.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KLO17542.1 - 0.041 13.7 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1072 PF06380.11 KLO17543.1 - 0.42 10.5 4.4 0.31 10.9 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) DUF4402 PF14352.6 KLO17548.1 - 0.34 11.6 9.4 1.2 9.8 3.2 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4402) Chs7 PF12271.8 KLO17549.1 - 4.5e-117 390.5 25.8 5.2e-117 390.3 25.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 KLO17549.1 - 0.13 12.5 3.9 0.31 11.3 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Glyco_transf_25 PF01755.17 KLO17550.1 - 0.00063 19.7 0.8 0.035 14.0 0.8 2.8 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) V-SNARE_C PF12352.8 KLO17552.1 - 0.076 13.3 0.7 0.15 12.3 0.7 1.4 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Cyclin PF08613.11 KLO17553.1 - 2e-17 64.0 0.2 5.1e-17 62.7 0.2 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KLO17553.1 - 3e-09 36.7 0.1 4.7e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SPO22 PF08631.10 KLO17555.1 - 5.7e-56 190.0 19.5 3.5e-54 184.1 6.7 3.5 3 0 0 3 3 3 3 Meiosis protein SPO22/ZIP4 like ANAPC3 PF12895.7 KLO17555.1 - 0.0071 16.6 0.9 0.0071 16.6 0.9 3.4 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KLO17555.1 - 0.028 14.5 3.0 0.98 9.6 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KLO17555.1 - 0.046 13.9 2.7 13 6.2 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KLO17555.1 - 0.079 13.3 7.8 15 6.0 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat EH_Signature PF15611.6 KLO17555.1 - 0.11 11.8 3.9 0.17 11.3 2.7 1.8 2 0 0 2 2 2 0 EH_Signature domain Miga PF10265.9 KLO17555.1 - 0.26 10.2 4.4 0.54 9.2 4.4 1.4 1 0 0 1 1 1 0 Mitoguardin TPR_6 PF13174.6 KLO17555.1 - 1.4 9.8 5.5 13 6.7 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 KLO17556.1 - 2.8e-08 34.0 0.0 0.0063 16.8 0.0 4.4 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KLO17556.1 - 3.2e-08 34.1 0.7 9.6 7.3 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF2415 PF10313.9 KLO17556.1 - 0.011 15.6 0.0 0.19 11.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) Coatomer_WDAD PF04053.14 KLO17556.1 - 0.13 11.2 0.0 0.61 9.1 0.0 1.8 2 0 0 2 2 2 0 Coatomer WD associated region G-alpha PF00503.20 KLO17557.1 - 1.1e-104 350.4 0.1 1.4e-104 350.0 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO17557.1 - 2.2e-11 43.5 2.1 7.6e-07 28.8 0.7 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KLO17557.1 - 0.0072 15.7 1.8 1.5 8.1 0.8 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region SNF2_N PF00176.23 KLO17557.1 - 0.011 14.5 0.1 0.018 13.7 0.1 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_29 PF13555.6 KLO17557.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KLO17557.1 - 0.03 14.4 0.0 4.9 7.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 KLO17557.1 - 0.035 14.3 0.7 0.91 9.8 0.0 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KLO17557.1 - 0.13 12.1 0.1 2.8 7.8 0.0 2.5 2 1 0 2 2 2 0 RsgA GTPase SCO1-SenC PF02630.14 KLO17565.1 - 0.13 12.2 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 SCO1/SenC DUF3712 PF12505.8 KLO17572.1 - 0.12 12.6 0.6 0.18 12.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3712) Med21 PF11221.8 KLO17573.1 - 3.2e-28 98.8 9.5 4.4e-28 98.3 9.5 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med30 PF11315.8 KLO17573.1 - 0.27 11.4 5.0 0.2 11.9 1.5 2.1 1 1 1 2 2 2 0 Mediator complex subunit 30 ZapB PF06005.12 KLO17573.1 - 0.27 11.7 6.5 2.7 8.5 0.1 2.5 2 0 0 2 2 2 0 Cell division protein ZapB IFP_35_N PF07334.13 KLO17573.1 - 0.29 11.2 3.8 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus BST2 PF16716.5 KLO17573.1 - 0.32 11.6 4.1 1.4 9.6 0.9 2.4 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 YjbH PF06082.11 KLO17573.1 - 0.7 8.6 2.7 0.73 8.6 2.7 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Cullin PF00888.22 KLO17574.1 - 3.9e-127 425.4 7.6 6.3e-127 424.8 7.6 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KLO17574.1 - 8.5e-24 83.4 2.7 8.5e-24 83.4 2.7 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain Ada_Zn_binding PF02805.16 KLO17574.1 - 0.078 13.0 0.2 0.55 10.3 0.1 2.2 2 0 0 2 2 2 0 Metal binding domain of Ada DcuC PF03606.15 KLO17574.1 - 0.21 10.0 0.1 0.32 9.4 0.1 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Ank_4 PF13637.6 KLO17575.1 - 2.3e-15 56.7 0.7 2.7e-08 34.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KLO17575.1 - 1.8e-12 46.2 0.5 0.00012 22.2 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KLO17575.1 - 5.3e-12 46.2 0.0 2.2e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KLO17575.1 - 9.8e-10 38.4 2.1 1.4e-05 25.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KLO17575.1 - 2e-08 34.3 1.3 0.00074 19.8 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) AAA PF00004.29 KLO17576.1 - 9.5e-18 64.9 0.0 3.5e-16 59.8 0.0 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KLO17576.1 - 3.7e-06 26.3 0.0 1.5e-05 24.3 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF815) BCS1_N PF08740.11 KLO17576.1 - 6e-05 23.1 0.2 6e-05 23.1 0.2 2.0 2 0 0 2 2 2 1 BCS1 N terminal AAA_16 PF13191.6 KLO17576.1 - 0.0002 21.8 0.5 0.0031 17.9 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 KLO17576.1 - 0.00056 19.8 1.7 0.51 10.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KLO17576.1 - 0.00068 19.6 0.2 0.0018 18.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KLO17576.1 - 0.0039 17.5 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF4746 PF15928.5 KLO17576.1 - 0.019 14.4 10.2 0.033 13.6 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AAA_3 PF07726.11 KLO17576.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KLO17576.1 - 0.026 14.1 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_6 PF12774.7 KLO17576.1 - 0.026 13.5 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 KLO17576.1 - 0.033 14.6 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KLO17576.1 - 0.039 14.5 0.7 0.43 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KLO17576.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KLO17576.1 - 0.12 11.7 2.6 0.23 10.8 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.6 KLO17576.1 - 0.17 12.3 5.4 6.9 7.1 3.8 2.4 2 0 0 2 2 2 0 AAA domain Ribosomal_S2 PF00318.20 KLO17576.1 - 2 7.6 4.3 9.7 5.3 3.7 2.0 2 0 0 2 2 2 0 Ribosomal protein S2 RPN2_C PF18004.1 KLO17576.1 - 5.1 7.0 18.4 16 5.4 0.0 2.5 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Rtf2 PF04641.12 KLO17577.1 - 6.3e-77 258.5 4.4 7.8e-77 258.2 4.4 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-UDP PF14569.6 KLO17577.1 - 0.0061 16.7 1.2 0.013 15.6 0.3 2.1 1 1 1 2 2 2 1 Zinc-binding RING-finger zf-NOSIP PF15906.5 KLO17577.1 - 0.012 15.7 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 KLO17577.1 - 0.02 14.7 0.1 0.47 10.3 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit MRP-S31 PF15433.6 KLO17577.1 - 0.22 11.1 8.3 0.34 10.5 8.3 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 PRTP PF01366.18 KLO17577.1 - 0.75 7.8 3.9 1.1 7.3 3.9 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein FYDLN_acid PF09538.10 KLO17577.1 - 8.4 7.1 10.6 42 4.9 10.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) PS_Dcarbxylase PF02666.15 KLO17578.1 - 4.2e-74 248.4 0.0 1.5e-71 240.1 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase SPX PF03105.19 KLO17578.1 - 2.2 8.1 6.6 3.2 7.6 6.6 1.2 1 0 0 1 1 1 0 SPX domain ChaC PF04752.12 KLO17579.1 - 8.2e-56 188.9 0.0 9.3e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 KLO17579.1 - 0.00079 20.0 0.1 0.0013 19.3 0.1 1.4 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like SKA2 PF16740.5 KLO17583.1 - 0.00039 20.2 0.6 0.065 13.0 0.2 2.5 2 0 0 2 2 2 2 Spindle and kinetochore-associated protein 2 Urotensin_II PF02083.15 KLO17583.1 - 0.25 11.1 2.7 0.47 10.2 2.7 1.4 1 0 0 1 1 1 0 Urotensin II DUF3752 PF12572.8 KLO17585.1 - 4.5e-39 134.4 5.7 4.5e-39 134.4 5.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Cas_Csy4 PF09618.10 KLO17585.1 - 0.07 13.3 1.7 0.11 12.7 1.7 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Nucleo_P87 PF07267.11 KLO17585.1 - 1.8 7.3 6.8 4.8 5.9 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 U1snRNP70_N PF12220.8 KLO17585.1 - 4 8.2 6.3 27 5.5 4.7 2.5 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Vps35 PF03635.17 KLO17589.1 - 0 1017.2 1.7 0 1017.0 1.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribonuc_L-PSP PF01042.21 KLO17589.1 - 0.037 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Endoribonuclease L-PSP UbiA PF01040.18 KLO17590.1 - 6.3e-27 94.5 5.2 6.3e-27 94.5 5.2 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family DUF21 PF01595.20 KLO17591.1 - 4e-32 111.3 0.0 7.2e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KLO17591.1 - 7.3e-06 26.3 0.5 0.28 11.6 0.0 3.3 3 0 0 3 3 3 2 CBS domain Polysacc_synt_3 PF13440.6 KLO17591.1 - 0.029 13.6 1.5 0.054 12.7 1.5 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.22 KLO17594.1 - 6.1e-73 246.1 0.0 6.9e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 KLO17595.1 - 1.3e-27 96.7 9.3 1.7e-27 96.3 9.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family CFEM PF05730.11 KLO17597.1 - 3.4e-09 36.7 13.1 5.2e-09 36.1 13.1 1.3 1 0 0 1 1 1 1 CFEM domain zf-MYND PF01753.18 KLO17598.1 - 1.4e-07 31.5 11.2 1.4e-07 31.5 11.2 2.3 3 0 0 3 3 3 1 MYND finger zf-RRPl_C4 PF17026.5 KLO17598.1 - 0.11 12.7 2.5 0.23 11.6 2.5 1.6 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF4704 PF15787.5 KLO17598.1 - 0.13 11.5 0.1 0.56 9.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) Rhodanese_C PF12368.8 KLO17598.1 - 0.26 11.7 3.5 0.62 10.5 3.5 1.6 1 0 0 1 1 1 0 Rhodanase C-terminal A2L_zn_ribbon PF08792.10 KLO17598.1 - 3.7 7.4 4.8 0.45 10.3 0.3 1.8 2 0 0 2 2 2 0 A2L zinc ribbon domain E7 PF00527.18 KLO17602.1 - 0.14 12.4 0.2 0.33 11.2 0.1 1.6 1 1 0 1 1 1 0 E7 protein, Early protein EcKinase PF02958.20 KLO17603.1 - 0.037 13.3 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase VHS PF00790.19 KLO17605.1 - 4.5e-44 149.7 0.4 3.5e-42 143.6 0.0 2.6 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KLO17605.1 - 9.7e-17 60.9 7.1 1.7e-16 60.1 7.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KLO17605.1 - 6.1e-05 22.7 13.6 0.0033 17.2 3.7 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KLO17605.1 - 0.0016 18.6 3.9 0.0034 17.6 3.9 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger GAT PF03127.14 KLO17605.1 - 0.0073 16.6 0.5 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 GAT domain DZR PF12773.7 KLO17605.1 - 0.054 13.5 7.7 0.73 9.9 3.9 2.4 1 1 1 2 2 2 0 Double zinc ribbon ADK_lid PF05191.14 KLO17605.1 - 0.2 11.7 2.2 0.79 9.8 2.2 2.1 1 0 0 1 1 1 0 Adenylate kinase, active site lid C1_1 PF00130.22 KLO17605.1 - 0.41 10.6 5.3 0.25 11.2 2.1 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 KLO17605.1 - 0.48 10.6 6.3 0.17 12.1 3.1 1.9 2 0 0 2 2 2 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 KLO17605.1 - 5.4 7.1 7.5 20 5.3 7.5 1.8 1 1 0 1 1 1 0 zinc-ribbons zf-MYND PF01753.18 KLO17608.1 - 3.4e-08 33.4 11.9 5.5e-08 32.8 11.9 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO17608.1 - 4.8 7.4 6.8 22 5.2 6.8 2.1 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ATP11 PF06644.11 KLO17609.1 - 3.6e-74 250.0 0.0 4.1e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein tRNA-synt_1c PF00749.21 KLO17610.1 - 4e-82 275.6 0.0 5.5e-82 275.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain TRAPP PF04051.16 KLO17612.1 - 1.8e-36 125.1 0.0 2.5e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component UPF0564 PF10595.9 KLO17612.1 - 0.028 13.5 2.3 0.039 13.0 2.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 zf-ANAPC11 PF12861.7 KLO17613.1 - 1.4e-39 134.0 9.7 1.7e-39 133.7 9.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KLO17613.1 - 1.8e-21 76.2 13.4 2.7e-21 75.6 13.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KLO17613.1 - 0.0012 19.1 17.8 0.018 15.4 17.8 2.4 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KLO17613.1 - 0.098 12.7 11.0 0.28 11.2 11.0 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KLO17613.1 - 0.14 12.1 14.7 0.59 10.1 14.7 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KLO17613.1 - 0.39 10.6 5.6 0.66 9.8 5.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 KLO17613.1 - 0.92 9.2 15.6 6.6 6.4 15.6 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KLO17613.1 - 2.4 8.2 15.0 42 4.2 15.9 2.6 1 1 1 2 2 2 0 zinc-RING finger domain PSP1 PF04468.12 KLO17614.1 - 2.1e-33 114.5 3.2 4.2e-33 113.5 3.2 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region TFIIA PF03153.13 KLO17614.1 - 1.9 8.4 21.9 0.022 14.8 8.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TMA7 PF09072.10 KLO17614.1 - 3.7 8.5 5.5 2.4 9.1 2.1 2.3 2 0 0 2 2 2 0 Translation machinery associated TMA7 Rgp1 PF08737.10 KLO17615.1 - 2.8e-55 188.2 0.1 6.2e-55 187.1 0.1 1.6 1 1 0 1 1 1 1 Rgp1 Arrestin_C PF02752.22 KLO17615.1 - 6.5e-08 33.1 0.2 0.072 13.5 0.0 4.3 3 1 1 4 4 4 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KLO17615.1 - 0.022 14.8 0.0 18 5.4 0.0 3.3 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 KLO17615.1 - 0.21 11.1 0.0 12 5.3 0.0 2.5 2 0 0 2 2 2 0 SpoOM protein zf-MYND PF01753.18 KLO17616.1 - 6.3e-09 35.8 9.9 1.2e-08 34.9 9.9 1.5 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 KLO17616.1 - 3 8.3 6.3 6.4 7.2 6.3 1.5 1 0 0 1 1 1 0 Rhodanase C-terminal zf-Mss51 PF13824.6 KLO17616.1 - 8 6.7 7.2 1.9e+02 2.3 0.1 2.6 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO17617.1 - 5.2e-09 36.0 9.1 8.3e-09 35.4 9.1 1.3 1 0 0 1 1 1 1 MYND finger A2L_zn_ribbon PF08792.10 KLO17617.1 - 0.15 11.8 2.0 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-HIT PF04438.16 KLO17617.1 - 1.5 8.7 7.5 3.5 7.6 7.5 1.6 1 1 0 1 1 1 0 HIT zinc finger zf-Mss51 PF13824.6 KLO17617.1 - 4.6 7.4 5.3 27 5.0 5.3 2.1 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO17618.1 - 3e-09 36.8 11.1 4.9e-09 36.1 11.1 1.4 1 0 0 1 1 1 1 MYND finger PCI PF01399.27 KLO17619.1 - 1.7e-05 25.3 1.8 3.1e-05 24.4 0.3 2.0 2 0 0 2 2 2 1 PCI domain TIP120 PF08623.10 KLO17620.1 - 3.9e-55 186.2 4.1 3e-54 183.3 0.5 3.9 4 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KLO17620.1 - 7.6e-13 48.7 20.1 0.015 15.6 0.4 8.7 8 2 1 9 9 8 3 HEAT repeats HEAT_EZ PF13513.6 KLO17620.1 - 1.5e-09 38.1 33.2 0.041 14.4 0.1 11.7 12 2 1 13 13 11 2 HEAT-like repeat HEAT PF02985.22 KLO17620.1 - 6.6e-09 35.3 33.9 0.031 14.5 0.0 12.3 14 0 0 14 14 12 3 HEAT repeat Adaptin_N PF01602.20 KLO17620.1 - 9.7e-09 34.3 10.6 2.2e-05 23.2 0.1 5.0 5 2 0 5 5 5 2 Adaptin N terminal region Cnd1 PF12717.7 KLO17620.1 - 6.2e-08 32.8 6.1 0.067 13.2 0.0 6.5 6 2 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 KLO17620.1 - 1.6e-07 31.2 0.4 0.14 12.1 0.0 5.3 4 1 0 4 4 4 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 KLO17620.1 - 9.3e-07 29.4 1.8 26 5.5 0.0 7.2 7 1 1 8 8 8 0 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 KLO17620.1 - 1.2e-05 25.0 0.9 4.4 6.7 0.0 5.4 5 0 0 5 5 5 1 Tti2 family TAF6_C PF07571.13 KLO17620.1 - 3.9e-05 23.9 0.1 0.9 9.9 0.0 4.3 3 1 0 3 3 3 2 TAF6 C-terminal HEAT repeat domain DUF4042 PF13251.6 KLO17620.1 - 0.00051 19.8 6.9 5.7 6.6 0.0 6.6 7 2 1 8 8 8 1 Domain of unknown function (DUF4042) Proteasom_PSMB PF10508.9 KLO17620.1 - 0.0054 15.3 0.8 0.032 12.8 0.1 2.5 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit RTP1_C1 PF10363.9 KLO17620.1 - 0.0058 16.8 6.1 0.15 12.2 0.2 4.9 6 0 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_N PF14500.6 KLO17620.1 - 0.0078 15.8 3.7 9.6 5.7 0.0 5.5 5 2 0 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II DRIM PF07539.12 KLO17620.1 - 0.024 13.0 4.0 5.4 5.2 1.3 4.2 3 2 1 4 4 4 0 Down-regulated in metastasis Cnd3 PF12719.7 KLO17620.1 - 0.031 13.5 2.3 2.9 7.0 0.1 4.1 5 0 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain TFCD_C PF12612.8 KLO17620.1 - 0.044 13.6 1.4 20 4.9 0.4 4.5 4 1 0 4 4 4 0 Tubulin folding cofactor D C terminal V-ATPase_H_C PF11698.8 KLO17620.1 - 0.063 13.4 0.6 4 7.6 0.5 3.8 4 0 0 4 4 3 0 V-ATPase subunit H MMS19_C PF12460.8 KLO17620.1 - 3.3 6.7 24.1 2 7.5 0.2 5.6 4 2 0 4 4 4 0 RNAPII transcription regulator C-terminal PBP1_TM PF14812.6 KLO17620.1 - 5.8 7.4 8.8 64 4.0 8.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pro_dh PF01619.18 KLO17621.1 - 2e-52 178.6 0.0 3.5e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 Proline dehydrogenase AAA_16 PF13191.6 KLO17622.1 - 0.00048 20.5 0.0 0.00069 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Acetyltransf_1 PF00583.25 KLO17623.1 - 1.2e-07 31.9 0.0 2.3e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KLO17623.1 - 7.4e-06 26.7 0.0 2.1e-05 25.2 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO17623.1 - 0.00017 21.5 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 KLO17623.1 - 0.054 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_4 PF13420.7 KLO17623.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-CCCH_2 PF14608.6 KLO17624.1 - 2.3e-11 43.7 28.6 7e-05 23.2 2.8 4.5 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger OHA PF14418.6 KLO17624.1 - 0.039 13.8 0.1 0.085 12.7 0.1 1.5 1 0 0 1 1 1 0 OST-HTH Associated domain zf-C3H1 PF10650.9 KLO17624.1 - 3.3 7.5 8.5 20 5.1 0.3 3.8 3 0 0 3 3 3 0 Putative zinc-finger domain ISK_Channel PF02060.15 KLO17625.1 - 0.46 10.2 2.9 0.63 9.8 0.4 2.2 2 0 0 2 2 2 0 Slow voltage-gated potassium channel DTHCT PF08070.11 KLO17625.1 - 1.5 9.5 18.7 0.18 12.6 10.3 2.4 2 0 0 2 2 2 0 DTHCT (NUC029) region BRF1 PF07741.13 KLO17625.1 - 8.2 6.8 23.6 6.4 7.2 9.6 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain AA_permease_2 PF13520.6 KLO17626.1 - 1.4e-70 238.3 39.3 1.7e-70 238.0 39.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3688 PF12461.8 KLO17626.1 - 0.14 10.5 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3688) PI3K_P85_iSH2 PF16454.5 KLO17627.1 - 0.0081 15.8 1.8 0.017 14.7 1.8 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Fib_alpha PF08702.10 KLO17627.1 - 0.033 14.4 0.4 0.077 13.2 0.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family F-box-like PF12937.7 KLO17627.1 - 0.04 13.8 0.3 0.088 12.7 0.3 1.6 1 0 0 1 1 1 0 F-box-like FTH PF01827.27 KLO17628.1 - 0.0034 17.2 0.3 0.0081 16.0 0.3 1.6 1 0 0 1 1 1 1 FTH domain F-box-like PF12937.7 KLO17629.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like CPSase_L_D2 PF02786.17 KLO17630.1 - 9.1e-108 358.6 0.0 6.5e-82 274.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KLO17630.1 - 1.9e-39 134.8 0.1 4.3e-39 133.6 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KLO17630.1 - 1.8e-17 63.4 0.0 2e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KLO17630.1 - 6e-12 45.4 0.0 3.6e-05 23.5 0.0 3.5 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 KLO17630.1 - 7.6e-12 45.2 0.0 5.1e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 KLO17630.1 - 2.1e-07 30.6 0.0 0.0049 16.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 KLO17630.1 - 1.2e-05 25.4 0.0 0.012 15.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 KLO17630.1 - 7.8e-05 22.3 0.0 0.056 13.0 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.19 KLO17630.1 - 0.084 12.6 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Sdh_cyt PF01127.22 KLO17631.1 - 2.2e-25 89.0 1.5 2.8e-25 88.7 1.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Lyase_aromatic PF00221.19 KLO17632.1 - 3.7e-145 484.2 0.8 4.8e-145 483.8 0.8 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Fcf1 PF04900.12 KLO17633.1 - 1.7e-38 131.0 1.0 3.3e-38 130.0 1.0 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KLO17633.1 - 1.5e-10 41.4 0.2 8.6e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 PIN like domain DAO PF01266.24 KLO17635.1 - 1.7e-35 123.2 0.0 2.2e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KLO17635.1 - 2.1e-05 24.5 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KLO17635.1 - 0.00014 21.3 0.0 0.00026 20.4 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KLO17635.1 - 0.00015 21.1 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KLO17635.1 - 0.012 14.8 0.0 0.081 12.0 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KLO17635.1 - 0.012 14.7 0.2 0.026 13.6 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A SNAD3 PF18749.1 KLO17635.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 Pyr_redox_3 PF13738.6 KLO17635.1 - 0.13 11.5 0.0 7.3 5.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KLO17637.1 - 1.3e-19 70.7 0.0 2e-19 70.1 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KLO17637.1 - 2.3e-08 34.0 3.4 0.0017 18.0 1.5 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KLO17637.1 - 3.4e-07 29.9 5.9 0.00047 19.6 0.2 3.9 3 1 1 4 4 4 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KLO17637.1 - 2.3e-05 23.8 1.6 0.00066 19.0 1.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO17637.1 - 4.5e-05 23.6 0.1 0.00011 22.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KLO17637.1 - 0.0011 18.1 0.4 0.0019 17.3 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KLO17637.1 - 0.0074 15.4 0.1 0.29 10.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KLO17637.1 - 0.0086 15.5 1.4 0.044 13.1 1.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KLO17637.1 - 0.013 14.2 0.2 0.75 8.4 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KLO17637.1 - 0.023 13.8 0.3 0.65 9.0 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KLO17637.1 - 0.026 13.8 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KLO17637.1 - 0.17 10.7 3.1 1.1 8.0 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.27 KLO17637.1 - 0.48 11.0 1.9 2.7 8.6 1.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DSPc PF00782.20 KLO17639.1 - 7.4e-05 22.6 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KLO17639.1 - 0.037 14.0 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KLO17639.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 KLO17639.1 - 0.19 11.3 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Cyclin_N PF00134.23 KLO17640.1 - 6.3e-42 142.3 0.5 5.9e-41 139.2 0.6 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KLO17640.1 - 7.6e-26 90.5 0.4 4.3e-24 84.9 0.0 2.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain tRNA-synt_1 PF00133.22 KLO17641.1 - 1.9e-148 495.4 0.0 2.5e-148 495.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KLO17641.1 - 9.8e-24 84.0 0.1 1.8e-23 83.2 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KLO17641.1 - 1.8e-21 76.3 0.0 6.6e-14 51.5 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KLO17641.1 - 0.0012 18.3 0.0 0.4 10.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 KLO17641.1 - 0.075 12.9 4.0 0.037 13.9 1.1 1.9 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS tRNA-synt_1b PF00579.25 KLO17641.1 - 0.081 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) MAD PF05557.13 KLO17642.1 - 0.0073 14.7 22.3 0.012 14.1 22.3 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein ADIP PF11559.8 KLO17642.1 - 0.1 12.7 26.9 0.059 13.5 12.3 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1690 PF07956.11 KLO17642.1 - 0.25 11.8 23.7 0.25 11.7 10.7 2.3 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) NPV_P10 PF05531.12 KLO17642.1 - 1.9 9.0 6.5 52 4.4 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 KLO17642.1 - 2.5 8.9 12.2 3.7 8.3 3.0 2.7 2 1 1 3 3 3 0 Occludin homology domain Spc7 PF08317.11 KLO17642.1 - 3.5 6.4 28.1 0.67 8.8 18.9 2.6 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 KLO17642.1 - 3.7 7.6 8.5 3.2 7.8 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Asp-B-Hydro_N PF05279.11 KLO17642.1 - 8.4 6.4 13.5 13 5.8 13.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FAD_binding_4 PF01565.23 KLO17643.1 - 6.7e-18 64.8 0.7 4.1e-17 62.2 1.1 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KLO17643.1 - 3.5e-10 39.8 0.1 6.1e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 KLO17644.1 - 8.8e-65 219.2 0.0 1.1e-64 219.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO17645.1 - 3.1e-60 204.2 0.0 3.7e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO17646.1 - 3.2e-61 207.5 0.0 4.1e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KLO17647.1 - 1.1e-17 64.1 1.2 3.2e-17 62.6 1.2 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KLO17647.1 - 5e-09 36.1 0.0 9.6e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like ProRS-C_1 PF09180.11 KLO17648.1 - 1.3e-27 95.8 1.1 3.2e-27 94.5 1.1 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KLO17648.1 - 5.8e-19 68.7 0.0 1.1e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KLO17648.1 - 2.7e-15 56.3 0.0 8.6e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA_edit PF04073.15 KLO17648.1 - 3.2e-07 30.5 0.0 7.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Zn-ribbon_8 PF09723.10 KLO17648.1 - 0.19 11.9 0.1 0.47 10.6 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain ADH_N PF08240.12 KLO17649.1 - 4.6e-33 113.3 1.8 9.1e-33 112.4 1.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO17649.1 - 1.2e-16 60.9 0.0 2.4e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KLO17649.1 - 8.3e-11 41.8 0.0 1.4e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KLO17649.1 - 1.4e-07 32.6 0.0 2.5e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KLO17649.1 - 1.4e-05 24.5 0.1 1.7e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 KLO17649.1 - 0.025 14.8 0.0 0.077 13.3 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ADH_N_2 PF16884.5 KLO17649.1 - 0.033 14.1 0.0 0.073 13.0 0.0 1.6 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase Shikimate_DH PF01488.20 KLO17649.1 - 0.054 13.6 0.2 0.12 12.5 0.2 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_24 PF13578.6 KLO17649.1 - 0.1 13.7 0.0 0.19 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.19 KLO17650.1 - 2e-26 92.6 0.0 3.3e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KLO17650.1 - 9.5e-12 44.6 0.0 1.1e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 KLO17650.1 - 4.9e-10 39.3 0.0 1.7e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO17650.1 - 2.6e-05 23.8 0.0 4.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KLO17650.1 - 4e-05 22.9 0.0 7.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KLO17650.1 - 0.00015 21.7 0.0 0.00046 20.2 0.0 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KLO17650.1 - 0.00071 19.5 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KLO17650.1 - 0.042 13.0 0.0 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain Oleosin PF01277.17 KLO17650.1 - 0.13 12.1 0.0 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Oleosin SURF4 PF02077.15 KLO17651.1 - 5e-94 314.8 7.6 5.7e-94 314.6 7.6 1.0 1 0 0 1 1 1 1 SURF4 family Halogen_Hydrol PF10112.9 KLO17651.1 - 1.8 8.6 10.7 2.9 7.9 0.4 2.8 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TrbE PF11100.8 KLO17651.1 - 1.9 8.8 7.0 0.17 12.1 1.8 2.0 2 0 0 2 2 2 0 Conjugal transfer protein TrbE Cyt-b5 PF00173.28 KLO17652.1 - 3.5e-20 71.9 0.3 1e-19 70.5 0.3 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KLO17652.1 - 1.5e-12 48.0 15.3 1.5e-12 48.0 15.3 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Fungal_trans PF04082.18 KLO17653.1 - 3.4e-36 124.7 0.0 4.9e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO17653.1 - 1.4e-07 31.5 11.2 2.6e-07 30.6 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KLO17654.1 - 2.9e-09 36.7 1.4 2.4e-08 33.7 0.3 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO17654.1 - 0.012 15.4 0.2 0.12 12.3 0.0 2.8 3 1 0 3 3 3 0 F-box domain HLH PF00010.26 KLO17655.1 - 5e-12 45.6 0.0 2.2e-11 43.5 0.1 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RXT2_N PF08595.11 KLO17655.1 - 0.0097 16.0 5.0 2.3 8.2 0.5 3.2 3 0 0 3 3 3 2 RXT2-like, N-terminal YL1 PF05764.13 KLO17655.1 - 0.022 14.9 0.2 0.022 14.9 0.2 3.0 4 0 0 4 4 4 0 YL1 nuclear protein Sigma70_ner PF04546.13 KLO17655.1 - 2.6 7.9 7.3 1.3 8.9 2.3 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region AT_hook PF02178.19 KLO17655.1 - 4.4 7.5 8.4 20 5.5 8.4 2.2 1 0 0 1 1 1 0 AT hook motif LANC_like PF05147.13 KLO17656.1 - 9.5e-07 27.7 0.0 3.7e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein BTB PF00651.31 KLO17657.1 - 0.0034 17.6 0.0 0.016 15.5 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-primase PF09329.11 KLO17657.1 - 0.062 13.1 0.2 0.17 11.7 0.2 1.7 1 0 0 1 1 1 0 Primase zinc finger Myb_DNA-bind_3 PF12776.7 KLO17660.1 - 2e-13 51.1 0.7 4.4e-13 50.0 0.7 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KLO17660.1 - 3.5e-05 24.1 2.4 7.6e-05 23.0 2.4 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KLO17660.1 - 0.069 13.5 1.1 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like NUC153 PF08159.12 KLO17661.1 - 3.5e-13 49.1 1.0 1.1e-12 47.5 1.0 1.9 1 0 0 1 1 1 1 NUC153 domain Tocopherol_cycl PF14249.6 KLO17662.1 - 2.6e-05 23.5 0.3 0.0045 16.2 0.1 2.4 2 0 0 2 2 2 2 Tocopherol cyclase RRF PF01765.19 KLO17663.1 - 2.9e-26 92.4 0.2 4e-26 91.9 0.2 1.2 1 0 0 1 1 1 1 Ribosome recycling factor WD40 PF00400.32 KLO17665.1 - 9e-45 149.8 24.6 3.4e-09 37.2 0.2 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO17665.1 - 8.2e-17 61.3 1.1 1e-05 25.7 0.0 5.6 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO17665.1 - 0.0035 16.4 0.1 6.9 5.5 0.0 3.6 3 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VCBS PF13517.6 KLO17665.1 - 0.015 15.8 2.5 0.31 11.7 0.0 3.8 5 0 0 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella lci PF12197.8 KLO17665.1 - 0.069 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein APH PF01636.23 KLO17666.1 - 2.7e-09 37.3 0.1 2.7e-08 34.1 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family UPF0147 PF03685.13 KLO17666.1 - 0.0093 16.0 0.7 0.21 11.7 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0147) SNF2_N PF00176.23 KLO17670.1 - 1.5e-62 211.4 3.9 2.4e-62 210.7 3.9 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO17670.1 - 2.9e-12 46.9 0.1 1.2e-11 44.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KLO17670.1 - 9.4e-09 35.0 8.7 2e-08 33.9 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO17670.1 - 3.3e-08 33.4 3.8 1e-07 31.8 3.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KLO17670.1 - 9.1e-08 32.3 6.4 2.2e-07 31.1 6.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KLO17670.1 - 9.8e-08 31.8 6.3 2.1e-07 30.7 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO17670.1 - 1.2e-07 31.5 5.2 2.5e-07 30.6 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KLO17670.1 - 2.1e-07 30.7 4.9 2.1e-07 30.7 4.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KLO17670.1 - 1.4e-05 25.2 1.0 3.9e-05 23.7 1.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 KLO17670.1 - 0.00056 19.7 8.4 0.0034 17.2 8.4 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KLO17670.1 - 0.00077 19.6 6.2 0.0019 18.3 6.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KLO17670.1 - 0.021 14.6 5.0 0.056 13.2 5.0 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-4CXXC_R1 PF10497.9 KLO17670.1 - 0.51 10.6 3.5 1.5 9.1 3.5 1.8 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Tmpp129 PF10272.9 KLO17670.1 - 1.7 7.8 4.6 2.8 7.1 4.6 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor p450 PF00067.22 KLO17671.1 - 1.9e-66 224.7 0.0 2.5e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rsa3 PF14615.6 KLO17671.1 - 0.098 12.2 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Ribosome-assembly protein 3 FAD_binding_3 PF01494.19 KLO17673.1 - 6.4e-16 58.5 0.0 8.8e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KLO17673.1 - 2.9e-06 27.4 0.1 9.1e-06 25.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO17673.1 - 4.1e-05 23.3 0.7 0.0012 18.5 0.4 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO17673.1 - 8.8e-05 21.8 0.1 0.00021 20.5 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO17673.1 - 0.00034 19.9 0.8 0.0063 15.8 0.1 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO17673.1 - 0.0014 19.1 0.2 0.0034 17.9 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KLO17673.1 - 0.0022 17.4 1.0 0.095 12.0 0.0 3.1 3 1 1 4 4 4 1 Flavin containing amine oxidoreductase RNase_H PF00075.24 KLO17673.1 - 0.026 14.7 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 RNase H Pyr_redox_3 PF13738.6 KLO17673.1 - 0.041 13.1 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO17673.1 - 0.15 10.7 0.0 0.65 8.6 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KLO17673.1 - 0.21 10.8 0.2 0.51 9.5 0.2 1.5 1 1 0 1 1 1 0 Thi4 family UbiA PF01040.18 KLO17674.1 - 4.4e-23 81.9 8.4 5.4e-23 81.6 7.9 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family ATP1G1_PLM_MAT8 PF02038.16 KLO17674.1 - 0.021 14.2 0.2 0.094 12.2 0.1 2.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Ndc1_Nup PF09531.10 KLO17675.1 - 0.12 11.1 4.3 0.17 10.5 4.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup p450 PF00067.22 KLO17676.1 - 7.3e-68 229.4 0.0 1.1e-67 228.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO17677.1 - 4.9e-70 236.6 0.0 5.6e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO17678.1 - 8.6e-20 70.9 0.0 9.6e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO17679.1 - 2.7e-36 125.3 0.0 3.6e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rer1 PF03248.13 KLO17680.1 - 3.2e-74 248.3 0.9 3.6e-74 248.2 0.9 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 KLO17680.1 - 0.032 13.9 4.5 0.063 12.9 4.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Steroid_dh PF02544.16 KLO17681.1 - 9.9e-28 97.0 8.0 1.2e-17 64.3 1.4 2.9 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KLO17681.1 - 3.5e-05 23.4 0.1 5.9e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) WD40 PF00400.32 KLO17682.1 - 1.6e-21 76.2 10.8 2.5e-06 28.1 0.4 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO17682.1 - 3.7e-07 30.3 0.0 0.00093 19.5 0.0 4.3 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO17682.1 - 0.0066 16.3 0.0 0.091 12.6 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.6 KLO17683.1 - 0.0034 17.8 0.0 0.0078 16.6 0.0 1.7 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KLO17683.1 - 0.078 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KLO17683.1 - 0.13 12.4 0.0 0.47 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KLO17683.1 - 0.17 11.9 0.0 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MIF4G PF02854.19 KLO17685.1 - 1.7e-34 119.3 0.1 1.9e-34 119.2 0.1 1.0 1 0 0 1 1 1 1 MIF4G domain DUF4763 PF15960.5 KLO17685.1 - 0.12 11.6 0.1 8.5 5.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) MIF4G PF02854.19 KLO17686.1 - 3.4e-32 111.8 8.1 5.2e-32 111.2 8.1 1.2 1 0 0 1 1 1 1 MIF4G domain WGG PF10273.9 KLO17686.1 - 0.0027 18.4 0.3 1.7 9.3 0.0 3.2 3 1 0 3 3 3 2 Pre-rRNA-processing protein TSR2 MIF4G PF02854.19 KLO17687.1 - 5.5e-29 101.3 0.0 6.4e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 MIF4G domain MOZART1 PF12554.8 KLO17687.1 - 0.09 12.6 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated MIF4G PF02854.19 KLO17689.1 - 9.7e-48 162.6 3.1 3.6e-47 160.7 2.4 2.2 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.8 KLO17689.1 - 3.7e-18 65.5 0.0 1.1e-17 64.0 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 KLO17689.1 - 1.4e-09 38.0 0.6 1.4e-08 34.7 0.0 2.6 3 0 0 3 3 3 1 MA3 domain Peptidase_C14 PF00656.22 KLO17690.1 - 4.2e-40 138.3 0.0 5.4e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KLO17690.1 - 0.09 12.7 0.1 0.43 10.5 0.1 1.9 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain Abhydrolase_1 PF00561.20 KLO17691.1 - 1.3e-22 80.7 0.1 5.7e-22 78.6 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KLO17691.1 - 2.6e-21 75.0 0.1 5.1e-21 74.0 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KLO17691.1 - 1.7e-05 24.2 0.0 0.0085 15.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KLO17691.1 - 0.0021 17.8 0.0 0.28 10.8 0.0 2.6 3 0 0 3 3 3 2 Serine hydrolase (FSH1) ADC PF06314.11 KLO17692.1 - 0.059 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) ADC PF06314.11 KLO17693.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) Methyltransf_25 PF13649.6 KLO17695.1 - 6.6e-12 46.0 0.0 2.1e-11 44.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO17695.1 - 3.5e-11 43.2 0.0 4.9e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO17695.1 - 1.4e-09 38.5 0.0 3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO17695.1 - 7.5e-09 35.3 0.0 9.1e-08 31.7 0.0 2.5 3 1 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KLO17695.1 - 9.9e-09 35.2 0.0 5e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO17695.1 - 6.1e-07 30.1 0.0 2.7e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KLO17695.1 - 0.00061 19.9 0.0 0.0008 19.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase TPMT PF05724.11 KLO17695.1 - 0.00073 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Glyco_hydro_61 PF03443.14 KLO17697.1 - 1.4e-54 185.1 0.8 2.3e-54 184.5 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KLO17697.1 - 1.2e-11 44.3 6.4 1.2e-11 44.3 6.4 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KLO17697.1 - 0.084 13.1 0.2 0.084 13.1 0.2 2.2 2 0 0 2 2 2 0 Toxin 7 Herpes_pp85 PF04637.12 KLO17698.1 - 0.039 12.4 9.6 0.19 10.1 7.6 2.0 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) IMUP PF15761.5 KLO17698.1 - 1.2 9.9 10.4 2.9 8.6 10.4 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 KLO17698.1 - 2.8 7.5 19.8 0.15 11.6 14.6 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SLATT_fungal PF18142.1 KLO17700.1 - 2.8e-39 133.8 0.1 3.6e-39 133.4 0.1 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Npa1 PF11707.8 KLO17700.1 - 0.0084 15.5 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Nbl1_Borealin_N PF10444.9 KLO17700.1 - 0.077 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal SLATT_fungal PF18142.1 KLO17701.1 - 9.7e-39 132.1 0.0 1.1e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Zw10 PF06248.13 KLO17701.1 - 0.17 10.4 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF883 PF05957.13 KLO17701.1 - 3.1 8.5 5.6 21 5.8 0.0 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) F-box PF00646.33 KLO17702.1 - 1.5e-09 37.5 0.7 3.1e-09 36.5 0.7 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO17702.1 - 5.2e-07 29.4 0.8 1.5e-06 28.0 0.8 1.7 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KLO17703.1 - 8.4e-35 120.3 29.3 8.4e-35 120.3 29.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TPR_1 PF00515.28 KLO17704.1 - 6.2e-14 51.1 1.9 3.7e-05 23.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat PB1 PF00564.24 KLO17704.1 - 6.2e-14 51.7 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_2 PF07719.17 KLO17704.1 - 3.7e-11 42.2 8.0 0.0025 17.8 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KLO17704.1 - 3.8e-09 36.7 4.2 1.1e-05 25.6 0.4 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KLO17704.1 - 4.7e-08 32.6 2.3 0.00064 19.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KLO17704.1 - 0.00024 21.5 5.3 16 6.4 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KLO17704.1 - 0.00095 18.8 3.2 0.0039 16.8 0.1 3.5 4 1 1 5 5 5 1 TPR repeat TPR_7 PF13176.6 KLO17704.1 - 0.0018 18.1 3.7 0.025 14.6 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KLO17704.1 - 0.024 15.2 1.0 22 6.0 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KLO17704.1 - 0.069 14.0 7.7 3.3 8.8 0.1 4.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KLO17704.1 - 0.12 13.0 0.5 0.12 13.0 0.5 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KLO17704.1 - 0.2 11.6 7.8 0.69 9.9 0.0 4.4 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KLO17704.1 - 0.21 12.1 4.4 1.1 9.8 0.4 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KLO17705.1 - 1.6e-08 34.0 0.0 2.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO17705.1 - 8.2e-07 29.1 8.5 1.3e-06 28.4 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyridoxal_deC PF00282.19 KLO17707.1 - 1.8e-18 66.4 0.0 1.9e-08 33.4 0.0 3.1 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain HSP70 PF00012.20 KLO17708.1 - 3.7e-263 874.2 16.0 4.3e-263 874.0 16.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KLO17708.1 - 2.9e-15 55.9 4.0 2.8e-13 49.4 2.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein DUF1722 PF08349.11 KLO17708.1 - 0.14 12.4 0.3 2.8 8.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) FtsA PF14450.6 KLO17708.1 - 0.24 11.8 10.9 3.3 8.2 0.1 4.2 3 3 0 3 3 3 0 Cell division protein FtsA APH PF01636.23 KLO17709.1 - 2.1e-36 126.1 0.0 2.8e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KLO17709.1 - 2.4e-05 24.0 0.0 0.00022 20.9 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 KLO17709.1 - 8e-05 22.1 0.0 0.00017 21.0 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase Arrestin_C PF02752.22 KLO17712.1 - 2.1e-15 57.3 0.0 2.2e-13 50.8 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KLO17712.1 - 1.1e-12 48.2 0.1 4.6e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KLO17712.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like Pkinase PF00069.25 KLO17715.1 - 2.1e-37 128.9 0.0 4.2e-37 128.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO17715.1 - 5.2e-31 107.9 0.0 7.2e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO17715.1 - 3.7e-05 23.2 0.0 7e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like IMS PF00817.20 KLO17715.1 - 0.18 11.8 0.0 0.9 9.5 0.0 2.1 1 1 0 1 1 1 0 impB/mucB/samB family BP28CT PF08146.12 KLO17716.1 - 1.2e-26 93.5 1.3 4.1e-26 91.7 0.4 2.6 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KLO17716.1 - 8.2e-10 39.1 1.8 8.2e-10 39.1 1.8 5.5 5 1 1 6 6 6 1 U3 small nucleolar RNA-associated protein 10 Gal-3-0_sulfotr PF06990.11 KLO17716.1 - 0.0042 16.0 0.1 0.0086 15.0 0.1 1.4 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase HEAT PF02985.22 KLO17716.1 - 0.015 15.5 0.3 0.015 15.5 0.3 5.4 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 KLO17716.1 - 0.017 15.6 0.2 0.017 15.6 0.2 3.9 3 0 0 3 3 3 0 HEAT-like repeat CLASP_N PF12348.8 KLO17716.1 - 0.017 14.7 1.3 1.8 8.1 0.0 3.6 3 0 0 3 3 3 0 CLASP N terminal SesA PF17107.5 KLO17716.1 - 0.017 15.3 1.0 9.2 6.5 0.0 3.4 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HEAT_2 PF13646.6 KLO17716.1 - 0.16 12.4 9.0 6 7.3 0.0 6.5 6 1 3 9 9 9 0 HEAT repeats DUF3385 PF11865.8 KLO17716.1 - 1.2 9.1 3.3 13 5.7 0.2 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) DUF1365 PF07103.11 KLO17717.1 - 1.5e-67 227.8 0.0 2.5e-67 227.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) F-box-like PF12937.7 KLO17718.1 - 2.6e-07 30.4 0.1 4.6e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO17718.1 - 7.2e-05 22.6 0.1 0.00012 21.9 0.1 1.3 1 0 0 1 1 1 1 F-box domain PPR_2 PF13041.6 KLO17719.1 - 1.6e-06 28.2 0.0 0.028 14.6 0.0 4.5 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 KLO17719.1 - 2.5e-05 24.2 0.0 0.2 11.8 0.0 3.4 3 0 0 3 3 3 2 Pentatricopeptide repeat domain DUF3368 PF11848.8 KLO17719.1 - 0.085 12.7 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) DUF4357 PF14267.6 KLO17719.1 - 0.14 12.2 0.6 0.3 11.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) PP28 PF10252.9 KLO17720.1 - 3e-05 24.4 6.4 3e-05 24.4 6.4 3.0 1 1 1 2 2 2 1 Casein kinase substrate phosphoprotein PP28 Red1 PF07964.11 KLO17720.1 - 0.25 9.5 7.3 0.29 9.3 7.3 1.1 1 0 0 1 1 1 0 Rec10 / Red1 LAP1C PF05609.12 KLO17720.1 - 0.77 8.8 14.3 0.93 8.5 14.3 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 KLO17720.1 - 3.5 6.9 28.3 4.3 6.6 28.3 1.1 1 0 0 1 1 1 0 BUD22 Complex1_LYR PF05347.15 KLO17721.1 - 2.2e-09 37.2 0.6 3.7e-09 36.5 0.6 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KLO17721.1 - 0.0056 17.4 0.0 0.0082 16.9 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RRM_1 PF00076.22 KLO17722.1 - 9.5e-14 51.0 0.0 1.3e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KLO17722.1 - 0.0067 16.4 0.0 0.0099 15.9 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Apt1 PF10351.9 KLO17722.1 - 4.7 6.0 6.8 5.2 5.8 6.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain eIF2_C PF09173.11 KLO17723.1 - 1e-29 102.6 0.1 2.3e-29 101.4 0.1 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KLO17723.1 - 8.3e-22 77.7 2.1 9e-21 74.3 2.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KLO17723.1 - 3.2e-10 40.3 0.0 8.8e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1_Xtn PF16897.5 KLO17723.1 - 0.0014 18.6 1.3 0.0027 17.7 0.2 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 KLO17723.1 - 0.0016 18.4 0.6 0.042 13.7 0.2 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KLO17723.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RINGv PF12906.7 KLO17725.1 - 4.1e-05 23.6 8.2 7e-05 22.9 8.2 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KLO17725.1 - 7.2e-05 22.9 4.0 0.00012 22.2 4.0 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain PHD_4 PF16866.5 KLO17725.1 - 0.05 13.7 6.9 0.096 12.8 6.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KLO17725.1 - 0.16 12.4 7.2 0.28 11.5 7.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-primase PF09329.11 KLO17726.1 - 1.4e-12 47.2 2.9 2.7e-12 46.3 2.9 1.5 1 0 0 1 1 1 1 Primase zinc finger Ish1 PF10281.9 KLO17727.1 - 3.6e-57 190.3 40.1 5.2e-12 45.9 0.2 8.0 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 KLO17727.1 - 4.5e-06 26.3 11.1 0.0081 15.9 0.0 7.0 8 0 0 8 8 8 2 HeH/LEM domain SAP PF02037.27 KLO17727.1 - 0.00012 21.8 0.0 9.6 6.1 0.0 5.0 5 0 0 5 5 5 1 SAP domain LEM PF03020.15 KLO17727.1 - 0.0025 17.4 0.0 11 5.7 0.0 4.6 6 0 0 6 6 6 1 LEM domain ABATE PF07336.11 KLO17727.1 - 0.048 14.3 1.3 11 6.7 0.1 4.3 6 1 1 7 7 6 0 Putative stress-induced transcription regulator GntR PF00392.21 KLO17727.1 - 0.11 12.2 0.5 0.42 10.3 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Slx4 PF09494.10 KLO17727.1 - 0.21 11.5 1.8 11 6.0 0.0 4.0 3 1 2 5 5 5 0 Slx4 endonuclease SAM_2 PF07647.17 KLO17727.1 - 0.69 10.1 9.4 12 6.1 0.2 5.0 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) ABC2_membrane_3 PF12698.7 KLO17727.1 - 0.74 8.9 7.5 0.84 8.7 5.2 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein ArAE_2_N PF10337.9 KLO17727.1 - 0.77 8.7 3.6 0.39 9.7 0.3 2.0 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal GYF PF02213.16 KLO17727.1 - 5.2 6.8 8.2 1.1 9.0 1.2 3.0 3 0 0 3 3 3 0 GYF domain ANAPC4_WD40 PF12894.7 KLO17730.1 - 0.0016 18.7 0.3 0.16 12.3 0.0 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KLO17730.1 - 0.006 17.4 0.1 13 6.8 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat RsbRD_N PF14361.6 KLO17731.1 - 0.11 13.2 0.2 6 7.6 0.0 2.9 1 1 2 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain ADH_zinc_N PF00107.26 KLO17732.1 - 1.4e-26 93.0 0.1 2.4e-26 92.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO17732.1 - 4.8e-17 63.3 0.0 7.6e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO17732.1 - 2.9e-11 43.2 0.2 8.3e-11 41.7 0.2 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF4589 PF15252.6 KLO17732.1 - 0.038 14.0 0.0 0.051 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) TrkA_N PF02254.18 KLO17732.1 - 0.044 14.0 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Ldh_1_C PF02866.18 KLO17733.1 - 1.1e-45 155.6 0.2 1.4e-45 155.2 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KLO17733.1 - 3.8e-44 150.2 0.1 5.5e-44 149.7 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KLO17733.1 - 0.025 13.9 0.3 0.41 9.9 0.0 2.7 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 KLO17733.1 - 0.035 13.1 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Lon_C PF05362.13 KLO17734.1 - 6.2e-63 212.1 1.6 7.9e-63 211.7 0.8 1.6 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KLO17734.1 - 7.7e-22 78.1 0.0 1.6e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KLO17734.1 - 1.9e-10 40.9 0.0 4.9e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LON_substr_bdg PF02190.16 KLO17734.1 - 3.5e-10 40.1 0.0 7.3e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 KLO17734.1 - 8e-06 25.7 0.0 2.2e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KLO17734.1 - 0.00011 22.6 1.6 0.0013 19.1 0.0 3.1 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KLO17734.1 - 0.00017 21.8 0.4 0.075 13.3 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KLO17734.1 - 0.00055 20.1 0.0 0.0026 17.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KLO17734.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KLO17734.1 - 0.011 15.5 0.0 0.046 13.5 0.0 2.0 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KLO17734.1 - 0.015 15.0 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KLO17734.1 - 0.02 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KLO17734.1 - 0.025 15.1 0.0 0.22 12.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KLO17734.1 - 0.053 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KLO17734.1 - 0.054 12.7 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KLO17734.1 - 0.095 12.1 0.1 0.73 9.2 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KLO17734.1 - 0.13 12.6 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KLO17734.1 - 0.17 11.8 0.1 1.2 9.0 0.0 2.3 3 0 0 3 3 3 0 NACHT domain AAA_7 PF12775.7 KLO17734.1 - 0.17 11.4 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KLO17734.1 - 2.5 8.5 0.0 2.5 8.5 0.0 2.7 2 1 0 2 2 1 0 AAA domain MFS_1 PF07690.16 KLO17736.1 - 1.7e-23 83.1 29.3 1.5e-12 47.1 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4407 PF14362.6 KLO17736.1 - 1.6 8.0 5.7 3.8 6.8 5.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 KLO17737.1 - 0.21 10.2 64.3 0.53 8.9 15.0 3.3 1 1 1 3 3 3 0 AAA domain NPV_P10 PF05531.12 KLO17737.1 - 1.1 9.7 28.2 8.7 6.9 3.8 6.8 5 3 0 5 5 5 0 Nucleopolyhedrovirus P10 protein MbeD_MobD PF04899.12 KLO17737.1 - 7.6 6.7 13.6 0.59 10.3 3.4 3.6 3 1 0 3 3 3 0 MbeD/MobD like CTP_transf_like PF01467.26 KLO17738.1 - 1.5e-24 86.8 0.0 2.4e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like SapA PF02199.15 KLO17738.1 - 0.035 14.4 0.5 0.063 13.6 0.5 1.4 1 0 0 1 1 1 0 Saposin A-type domain TFA2_Winged_2 PF18121.1 KLO17739.1 - 2.7e-21 75.0 0.0 6.6e-21 73.8 0.0 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KLO17739.1 - 6.9e-13 48.7 0.1 3.7e-12 46.4 0.1 2.1 2 0 0 2 2 2 1 TFIIE beta subunit core domain Pan3_PK PF18101.1 KLO17740.1 - 6.1e-62 207.7 0.0 1e-61 206.9 0.0 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KLO17740.1 - 0.0085 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_S7 PF00177.21 KLO17740.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e PAP_assoc PF03828.19 KLO17741.1 - 1.5e-17 63.5 0.3 5.5e-17 61.7 0.2 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KLO17741.1 - 5.4e-06 26.6 0.0 1.6e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KLO17741.1 - 0.033 14.3 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF3563 PF12086.8 KLO17741.1 - 0.071 12.8 0.1 0.22 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) LSM PF01423.22 KLO17742.1 - 6e-19 67.5 0.0 8.3e-19 67.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KLO17742.1 - 0.059 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain HEAT_EZ PF13513.6 KLO17743.1 - 2.4e-15 56.6 8.9 2e-11 44.1 0.0 7.5 7 1 1 8 8 8 1 HEAT-like repeat HEAT PF02985.22 KLO17743.1 - 3e-13 48.8 13.3 0.0031 17.6 0.0 9.2 11 0 0 11 11 11 3 HEAT repeat IBN_N PF03810.19 KLO17743.1 - 2.5e-09 36.9 0.7 1.3e-07 31.5 0.2 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KLO17743.1 - 8.7e-09 35.7 4.3 0.07 13.5 0.0 7.0 3 3 2 6 6 6 3 HEAT repeats Arm PF00514.23 KLO17743.1 - 7.6e-07 29.0 7.3 0.11 12.6 0.0 7.1 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 KLO17743.1 - 0.00036 20.5 3.9 0.47 10.4 0.3 4.9 4 2 0 5 5 5 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 KLO17743.1 - 0.0011 18.6 0.3 0.16 11.5 0.2 4.1 3 2 1 4 4 4 1 CLASP N terminal V1R PF03402.14 KLO17743.1 - 0.081 12.5 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Vomeronasal organ pheromone receptor family, V1R TIP120 PF08623.10 KLO17743.1 - 1.9 8.2 4.2 2.3 8.0 0.1 3.2 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) Amidohydro_3 PF07969.11 KLO17744.1 - 5.9e-90 303.0 0.0 7.1e-90 302.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KLO17744.1 - 2.4e-11 43.6 0.0 4.2e-08 32.9 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family DSPc PF00782.20 KLO17745.1 - 5.9e-24 84.4 0.0 1e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KLO17745.1 - 0.00041 20.8 0.0 0.0013 19.2 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 KLO17745.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase eIF-5a PF01287.20 KLO17747.1 - 7e-27 93.3 0.7 1e-26 92.8 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KLO17747.1 - 0.049 13.7 0.1 0.077 13.0 0.1 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain CUE PF02845.16 KLO17748.1 - 1.6e-10 40.4 0.0 3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 KLO17748.1 - 1.8e-06 27.9 0.5 7.9e-06 25.9 0.5 2.1 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 SRAP PF02586.14 KLO17749.1 - 5.2e-69 232.1 0.1 7e-69 231.7 0.1 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Bromo_TP PF07524.13 KLO17750.1 - 5.3e-09 36.0 0.2 1.9e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 Bromodomain associated CENP-T_C PF15511.6 KLO17750.1 - 0.048 13.8 0.1 0.59 10.3 0.0 2.3 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T histone fold APC1_C PF18122.1 KLO17751.1 - 1.2e-34 119.6 0.1 2.4e-34 118.7 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 KLO17751.1 - 2.2e-06 28.3 0.1 0.0012 19.4 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KLO17751.1 - 0.00048 20.4 12.1 0.3 11.6 0.0 5.2 5 0 0 5 5 5 2 Proteasome/cyclosome repeat DUF5127 PF17168.4 KLO17752.1 - 5.1e-67 226.0 4.5 5.1e-67 226.0 4.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO17752.1 - 2e-52 177.4 2.5 2e-52 177.4 2.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO17752.1 - 5.9e-45 153.7 0.4 1.6e-44 152.2 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO17752.1 - 0.00062 19.3 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) MatE PF01554.18 KLO17753.1 - 1.5e-36 125.4 14.6 1.8e-21 76.5 7.4 3.1 2 1 0 2 2 2 2 MatE UPF0242 PF06785.11 KLO17753.1 - 0.0034 17.5 0.0 0.0076 16.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Arginase PF00491.21 KLO17754.1 - 7.9e-87 291.3 0.0 1e-86 290.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KLO17754.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain AA_permease_2 PF13520.6 KLO17755.1 - 3.5e-59 200.8 53.8 4.1e-59 200.5 53.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KLO17755.1 - 1.2e-20 73.6 46.2 1.7e-20 73.1 46.2 1.1 1 0 0 1 1 1 1 Amino acid permease Glucodextran_B PF09136.10 KLO17755.1 - 0.21 12.0 3.2 2 8.9 0.4 3.0 2 0 0 2 2 2 0 Glucodextranase, domain B LRR_4 PF12799.7 KLO17757.1 - 0.0095 16.3 4.2 2.2 8.8 0.1 3.8 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KLO17757.1 - 0.025 14.3 2.8 0.22 11.3 0.1 3.3 3 1 1 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 KLO17757.1 - 0.18 12.5 2.5 4.7 8.1 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich Repeat DHHC PF01529.20 KLO17758.1 - 1.2e-31 109.6 9.2 1.2e-31 109.6 9.2 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Colicin_V PF02674.16 KLO17758.1 - 0.44 10.5 5.7 1 9.3 1.7 2.2 2 0 0 2 2 2 0 Colicin V production protein Aminotran_3 PF00202.21 KLO17759.1 - 1.8e-119 399.1 0.0 2.1e-119 398.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KLO17759.1 - 0.008 15.5 0.0 0.033 13.5 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase dCMP_cyt_deam_1 PF00383.23 KLO17760.1 - 2.3e-11 43.5 0.4 3.2e-08 33.4 0.1 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KLO17760.1 - 0.00057 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 MafB19-like deaminase DUF612 PF04747.12 KLO17760.1 - 0.0099 15.0 0.2 0.014 14.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF612 MPP6 PF10175.9 KLO17761.1 - 3e-08 34.2 0.8 3e-08 34.2 0.8 2.0 3 1 0 3 3 3 1 M-phase phosphoprotein 6 zf-MYND PF01753.18 KLO17762.1 - 1.5e-10 41.0 11.7 1.5e-10 41.0 11.7 2.7 3 0 0 3 3 3 1 MYND finger zf-Sec23_Sec24 PF04810.15 KLO17762.1 - 0.033 14.2 1.0 0.033 14.2 1.0 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-Mss51 PF13824.6 KLO17762.1 - 2.8 8.1 9.3 0.89 9.7 4.9 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO17763.1 - 2.1e-10 40.5 14.3 2.1e-10 40.5 14.3 2.3 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 KLO17763.1 - 4.5 7.4 10.2 0.54 10.4 5.9 1.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO17771.1 - 1.1e-10 41.4 12.2 1.1e-10 41.4 12.2 2.3 3 0 0 3 3 3 1 MYND finger Baculo_PEP_C PF04513.12 KLO17772.1 - 0.0036 17.4 0.3 0.0085 16.1 0.2 1.7 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KLO17772.1 - 0.23 10.3 3.2 0.33 9.8 3.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1640 PF07798.11 KLO17772.1 - 5.1 7.1 5.8 3.7 7.6 2.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1640) LIM PF00412.22 KLO17775.1 - 2e-24 85.5 24.5 6.5e-13 48.7 7.7 2.2 2 0 0 2 2 2 2 LIM domain zf-dskA_traR PF01258.17 KLO17775.1 - 0.0077 16.2 0.5 0.0077 16.2 0.5 4.4 5 0 0 5 5 5 1 Prokaryotic dksA/traR C4-type zinc finger zf-RRN7 PF11781.8 KLO17775.1 - 0.0093 15.6 0.7 0.0093 15.6 0.7 3.8 5 0 0 5 5 5 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-RING_14 PF17978.1 KLO17775.1 - 0.64 10.5 5.8 3.8 8.0 1.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 KLO17775.1 - 3.2 7.9 21.5 0.51 10.5 2.6 4.3 5 0 0 5 5 5 0 Zinc ribbon domain Lar_restr_allev PF14354.6 KLO17775.1 - 6 7.3 18.0 1.1 9.7 2.1 3.2 2 2 1 3 3 3 0 Restriction alleviation protein Lar zf-RanBP PF00641.18 KLO17776.1 - 0.0087 15.4 6.6 0.024 13.9 3.7 2.4 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others EF1G PF00647.19 KLO17779.1 - 9.1e-42 141.5 0.1 2.5e-41 140.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 KLO17779.1 - 8.7e-13 48.4 0.1 3.7e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO17779.1 - 4.2e-11 42.7 0.0 1.1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KLO17779.1 - 3.2e-10 40.1 0.0 3.2e-10 40.1 0.0 2.4 2 1 0 2 2 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO17779.1 - 2.5e-08 34.0 0.2 1.1e-07 31.9 0.0 2.2 2 0 0 2 2 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KLO17779.1 - 2e-06 27.5 0.6 8.4e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KLO17779.1 - 1.1e-05 25.8 0.0 2.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO17779.1 - 0.0049 17.1 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DAD PF02109.16 KLO17779.1 - 0.076 13.3 0.7 3.5 8.0 0.1 2.9 2 1 1 3 3 3 0 DAD family SpoVR PF04293.13 KLO17779.1 - 0.12 11.1 0.9 0.2 10.3 0.9 1.3 1 0 0 1 1 1 0 SpoVR like protein Pox_Ag35 PF03286.14 KLO17779.1 - 0.9 9.3 8.2 1.5 8.6 8.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 KLO17779.1 - 1.1 8.9 3.8 1.8 8.2 3.8 1.3 1 0 0 1 1 1 0 FAM176 family Bac_rhamnosid6H PF17389.2 KLO17780.1 - 8.3e-17 61.4 0.0 1.3e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KLO17780.1 - 1.1e-06 28.4 0.1 2e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KLO17780.1 - 0.00077 18.4 0.3 0.0012 17.8 0.3 1.1 1 0 0 1 1 1 1 Trehalase ABA_GPCR PF12430.8 KLO17781.1 - 3.6e-35 121.4 4.5 3.6e-35 121.4 4.5 1.8 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KLO17781.1 - 5.7e-08 32.7 0.1 1.6e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal 2OG-FeII_Oxy_2 PF13532.6 KLO17782.1 - 2.9e-12 47.2 0.0 1.1e-10 42.0 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cullin_binding PF03556.15 KLO17784.1 - 1.3e-29 103.1 0.4 2.6e-29 102.1 0.4 1.5 1 0 0 1 1 1 1 Cullin binding MARVEL PF01284.23 KLO17786.1 - 0.00095 19.2 2.1 0.12 12.4 0.0 2.0 1 1 1 2 2 2 2 Membrane-associating domain MARVEL PF01284.23 KLO17788.1 - 0.0014 18.6 8.2 0.0022 18.0 8.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain ECF_trnsprt PF12822.7 KLO17788.1 - 0.0073 16.4 3.4 0.0073 16.4 3.4 1.4 1 1 0 1 1 1 1 ECF transporter, substrate-specific component SKN1 PF03935.15 KLO17789.1 - 6.1e-193 641.8 5.0 6.9e-193 641.6 5.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) TLD PF07534.16 KLO17790.1 - 9.6e-29 100.4 0.0 1.4e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 TLD Hexokinase_2 PF03727.16 KLO17791.1 - 2.7e-83 279.1 0.0 3.9e-83 278.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KLO17791.1 - 2.3e-66 223.5 0.0 3.4e-66 222.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase MFS_1 PF07690.16 KLO17792.1 - 8.2e-30 103.9 30.4 1.3e-29 103.3 30.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_92 PF07971.12 KLO17793.1 - 2.4e-105 353.1 0.3 2.2e-79 267.5 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KLO17793.1 - 9.7e-47 159.9 1.1 2.2e-46 158.7 1.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain WD40 PF00400.32 KLO17794.1 - 1.4e-21 76.3 20.0 1.6e-05 25.6 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 KLO17794.1 - 3.5e-15 56.3 0.0 8.6e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 KLO17794.1 - 2e-06 28.0 0.1 0.6 10.4 0.0 4.2 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KLO17794.1 - 0.0019 18.2 0.0 1.5 8.9 0.0 2.6 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KLO17794.1 - 0.027 13.2 1.5 0.31 9.6 0.1 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DHQS PF01959.16 KLO17794.1 - 0.23 10.3 0.0 0.34 9.8 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase II Aldo_ket_red PF00248.21 KLO17795.1 - 1.3e-64 218.3 0.0 1.4e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_ABA_S PF18066.1 KLO17795.1 - 0.15 12.8 0.0 0.35 11.6 0.0 1.6 1 0 0 1 1 1 0 Phage ABA sandwich domain Melibiase_2 PF16499.5 KLO17796.1 - 1.9e-50 171.6 1.9 3.2e-50 170.9 1.9 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KLO17796.1 - 3.1e-15 56.0 0.1 9.4e-14 51.3 0.0 2.4 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KLO17796.1 - 0.019 13.9 0.0 0.036 13.0 0.0 1.4 1 0 0 1 1 1 0 Melibiase Melibiase_2 PF16499.5 KLO17797.1 - 5.6e-57 193.1 2.5 9e-57 192.4 2.5 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KLO17797.1 - 2.7e-14 53.0 0.2 4.5e-13 49.1 0.1 2.3 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KLO17797.1 - 0.00034 19.7 0.1 0.00056 19.0 0.1 1.2 1 0 0 1 1 1 1 Melibiase Ribosomal_L14 PF00238.19 KLO17798.1 - 1.7e-47 160.5 0.4 1.9e-47 160.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e BTB PF00651.31 KLO17799.1 - 0.00012 22.3 0.0 0.00032 20.9 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain SDA1 PF05285.12 KLO17799.1 - 0.0057 16.1 5.7 0.0057 16.1 5.7 2.2 2 0 0 2 2 2 1 SDA1 Ndc1_Nup PF09531.10 KLO17799.1 - 0.19 10.4 7.4 0.3 9.7 7.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 KLO17799.1 - 0.49 10.3 17.7 1.2 9.0 13.1 2.1 2 0 0 2 2 2 0 SPX domain Macoilin PF09726.9 KLO17799.1 - 0.97 7.9 6.2 1.4 7.4 6.2 1.2 1 0 0 1 1 1 0 Macoilin family Sec10 PF07393.11 KLO17799.1 - 1.7 7.0 5.4 2.3 6.5 5.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Apt1 PF10351.9 KLO17799.1 - 9.5 4.9 11.8 0.24 10.2 4.6 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain RskA PF10099.9 KLO17800.1 - 0.063 13.6 0.0 0.12 12.6 0.0 1.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA ICMT PF04140.14 KLO17801.1 - 6.4e-12 45.7 0.0 1.6e-11 44.5 0.0 1.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KLO17801.1 - 4.8e-07 30.1 0.1 9.9e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KLO17801.1 - 3.6e-05 22.7 0.0 9.3e-05 21.4 0.0 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ABC2_membrane_2 PF12679.7 KLO17801.1 - 0.064 12.5 0.1 0.074 12.3 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DIL PF01843.19 KLO17801.1 - 0.19 12.0 0.0 0.29 11.4 0.0 1.2 1 0 0 1 1 1 0 DIL domain ICMT PF04140.14 KLO17802.1 - 2.3e-12 47.2 1.4 5.4e-12 46.0 0.1 2.3 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KLO17802.1 - 8.9e-08 32.5 1.6 3.9e-07 30.4 0.2 2.4 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KLO17802.1 - 7.1e-07 28.3 0.4 1.2e-06 27.6 0.4 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 KLO17803.1 - 4.1e-11 43.2 0.8 6e-11 42.6 0.0 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KLO17803.1 - 1.3e-07 31.9 0.8 3.4e-07 30.6 0.2 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KLO17803.1 - 0.00012 21.0 0.0 0.0008 18.3 0.0 2.0 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Sod_Fe_C PF02777.18 KLO17804.1 - 2.5e-33 114.3 0.1 4.9e-33 113.3 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KLO17804.1 - 4.7e-32 110.3 3.9 5.6e-32 110.1 2.6 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AAA PF00004.29 KLO17805.1 - 3.4e-12 46.9 0.0 1.2e-11 45.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KLO17805.1 - 0.0056 17.1 0.2 0.029 14.7 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO17805.1 - 0.077 13.3 2.2 2.1 8.6 0.0 3.4 3 1 1 4 4 4 0 AAA domain MeaB PF03308.16 KLO17805.1 - 0.19 10.7 0.0 0.34 9.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Sigma70_ner PF04546.13 KLO17805.1 - 1.6 8.6 8.8 3.7 7.4 8.8 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region p450 PF00067.22 KLO17806.1 - 1.1e-73 248.6 0.0 1.4e-73 248.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Plavaka PF18759.1 KLO17808.1 - 9.8e-111 370.1 0.3 9.8e-111 370.1 0.3 1.6 2 0 0 2 2 2 1 Plavaka transposase Sgf11 PF08209.11 KLO17808.1 - 0.25 10.9 4.9 0.75 9.4 4.9 1.8 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) CID_GANP PF16766.5 KLO17809.1 - 0.018 15.2 0.4 0.039 14.2 0.4 1.5 1 0 0 1 1 1 0 Binding region of GANP to ENY2 YhzD PF14120.6 KLO17809.1 - 0.092 12.9 0.5 0.24 11.5 0.5 1.8 1 0 0 1 1 1 0 YhzD-like protein SOG2 PF10428.9 KLO17809.1 - 2.1 7.5 12.2 2.9 7.0 12.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein FAM195 PF14799.6 KLO17810.1 - 0.086 13.2 0.1 5 7.5 0.0 2.1 1 1 1 2 2 2 0 FAM195 family DUF3328 PF11807.8 KLO17813.1 - 8.2e-14 51.9 0.8 1.1e-12 48.2 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) FtsK_4TM PF13491.6 KLO17814.1 - 3 7.5 10.9 0.081 12.6 1.0 2.3 1 1 1 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE FtsK_4TM PF13491.6 KLO17815.1 - 2.4 7.8 12.6 0.041 13.6 1.8 2.2 1 1 1 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE DUF3328 PF11807.8 KLO17816.1 - 1.4e-07 31.6 0.2 1e-06 28.7 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) p450 PF00067.22 KLO17820.1 - 2.3e-63 214.6 0.0 2.6e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.21 KLO17822.1 - 1.2e-66 224.9 0.0 1.4e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RTA1 PF04479.13 KLO17823.1 - 5e-52 176.5 9.5 5e-52 176.5 9.5 1.3 2 0 0 2 2 2 1 RTA1 like protein SRTM1 PF15872.5 KLO17823.1 - 0.29 11.3 1.0 0.42 10.8 0.1 1.7 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 DUF2208 PF09973.9 KLO17823.1 - 0.33 10.6 5.0 0.48 10.0 4.4 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2208) Phage_holin_3_6 PF07332.11 KLO17823.1 - 0.66 10.0 7.8 4.8 7.2 1.7 2.7 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RTA1 PF04479.13 KLO17824.1 - 1.2e-48 165.5 8.6 1.2e-48 165.5 8.6 1.7 2 0 0 2 2 2 1 RTA1 like protein DUF2070 PF09843.9 KLO17824.1 - 0.14 10.4 7.4 0.22 9.8 7.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4381 PF14316.6 KLO17824.1 - 1 9.6 2.5 21 5.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) MHYT PF03707.16 KLO17824.1 - 1.7 8.9 6.2 14 5.9 0.1 3.2 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat DUF202 PF02656.15 KLO17824.1 - 1.8 9.1 9.8 0.92 10.0 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Ferritin_2 PF13668.6 KLO17825.1 - 1e-38 132.6 0.2 2e-38 131.7 0.2 1.4 1 0 0 1 1 1 1 Ferritin-like domain RTA1 PF04479.13 KLO17830.1 - 9.6e-45 152.7 13.1 9.6e-45 152.7 13.1 1.4 1 1 0 1 1 1 1 RTA1 like protein p450 PF00067.22 KLO17831.1 - 9.6e-68 229.0 0.0 1.2e-67 228.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_15 PF01793.16 KLO17832.1 - 5.8e-22 78.4 7.1 7.4e-22 78.0 7.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NmrA PF05368.13 KLO17833.1 - 1.8e-33 116.0 0.0 2.4e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO17833.1 - 1.1e-16 61.3 0.0 2.1e-16 60.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KLO17833.1 - 3e-05 24.3 0.0 8.8e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KLO17833.1 - 6e-05 22.6 0.0 0.00087 18.8 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO17833.1 - 0.0025 16.9 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KLO17833.1 - 0.0059 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KLO17833.1 - 0.01 16.2 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KLO17834.1 - 5e-32 111.3 0.0 7.3e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO17834.1 - 1.2e-15 57.8 0.0 4.7e-15 56.0 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KLO17834.1 - 9.6e-05 22.4 0.1 0.00016 21.6 0.1 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KLO17834.1 - 0.00062 20.0 0.1 0.0025 18.1 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KLO17834.1 - 0.0034 17.5 0.0 0.0064 16.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KLO17834.1 - 0.0046 17.5 0.0 0.024 15.2 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KLO17834.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KLO17834.1 - 0.018 15.5 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KLO17834.1 - 0.019 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.6 KLO17834.1 - 0.025 15.0 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Ferritin_2 PF13668.6 KLO17835.1 - 3.5e-40 137.4 0.8 6.4e-40 136.5 0.5 1.6 2 0 0 2 2 2 1 Ferritin-like domain Peptidase_C54 PF03416.19 KLO17837.1 - 6.2e-101 337.4 0.0 8.5e-101 337.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 AMP-binding PF00501.28 KLO17840.1 - 2.5e-42 145.0 0.0 3.5e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KLO17840.1 - 5.2e-06 26.3 0.0 9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus TFX_C PF14601.6 KLO17840.1 - 0.18 11.8 0.1 0.38 10.8 0.1 1.5 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term Acetyltransf_3 PF13302.7 KLO17841.1 - 8.6e-24 84.8 0.0 1.1e-23 84.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KLO17841.1 - 3.7e-08 33.2 0.2 2e-07 30.8 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO17841.1 - 3.2e-05 23.8 0.0 0.00019 21.3 0.0 2.0 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KLO17841.1 - 7.3e-05 23.0 0.0 0.0005 20.3 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KLO17841.1 - 0.013 15.9 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KLO17841.1 - 0.038 13.6 0.0 0.14 11.7 0.0 2.0 2 1 0 2 2 2 0 GNAT acetyltransferase Acetyltransf_10 PF13673.7 KLO17841.1 - 0.057 13.4 0.5 2.4 8.1 0.0 2.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KLO17841.1 - 0.057 13.5 0.1 0.17 12.0 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ras PF00071.22 KLO17842.1 - 8.5e-38 129.5 0.0 1.2e-36 125.7 0.0 2.0 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KLO17842.1 - 7e-31 106.9 0.0 1.1e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO17842.1 - 1.6e-10 40.7 0.0 3.9e-10 39.5 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KLO17842.1 - 0.00042 19.8 0.0 0.00064 19.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KLO17842.1 - 0.0028 17.7 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KLO17842.1 - 0.0032 17.0 0.0 0.018 14.6 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain HEPN_SAV_6107 PF18726.1 KLO17842.1 - 0.071 13.6 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 SAV_6107-like HEPN PduV-EutP PF10662.9 KLO17842.1 - 0.11 12.3 0.0 0.46 10.2 0.0 2.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KLO17842.1 - 0.28 10.9 0.6 0.53 10.0 0.2 1.6 2 0 0 2 2 2 0 AAA domain ArAE_2 PF10334.9 KLO17843.1 - 8.1e-53 179.6 0.0 1.3e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 KLO17843.1 - 4.8e-39 134.7 6.0 2e-37 129.3 3.5 3.5 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KLO17843.1 - 2.3e-08 34.2 16.1 2.3e-08 34.2 16.1 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 KLO17843.1 - 0.7 8.7 10.2 1.4 7.7 10.2 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter FMO-like PF00743.19 KLO17844.1 - 1.6e-17 63.2 0.1 8.4e-16 57.5 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KLO17844.1 - 4.8e-17 62.2 0.0 9e-15 54.7 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KLO17844.1 - 1.5e-12 47.4 0.0 4.2e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KLO17844.1 - 6.4e-09 35.4 0.0 7.9e-06 25.2 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KLO17844.1 - 3.4e-05 24.3 0.0 0.24 12.0 0.0 3.9 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO17844.1 - 0.00029 21.0 0.4 0.009 16.2 0.0 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KLO17844.1 - 0.00033 20.0 0.1 0.0045 16.3 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KLO17844.1 - 0.00087 18.7 0.0 0.18 11.2 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KLO17844.1 - 0.0016 17.6 0.2 0.062 12.4 0.1 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 KLO17844.1 - 0.0054 16.6 0.2 0.68 9.8 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KLO17844.1 - 0.018 13.7 0.0 0.075 11.7 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KLO17844.1 - 0.021 14.4 0.1 0.69 9.4 0.0 2.8 3 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO17844.1 - 0.04 13.0 0.1 0.18 10.9 0.2 1.9 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KLO17844.1 - 0.059 12.6 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KLO17844.1 - 0.082 11.9 0.0 0.99 8.4 0.1 2.6 4 0 0 4 4 4 0 Lycopene cyclase protein SnoaL_2 PF12680.7 KLO17844.1 - 0.085 13.5 0.0 0.22 12.2 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain Acetyltransf_8 PF13523.6 KLO17845.1 - 1.9e-35 121.6 0.6 3.3e-35 120.9 0.6 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KLO17845.1 - 0.00067 20.4 0.1 0.0017 19.0 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UPF0016 PF01169.19 KLO17846.1 - 4.2e-42 142.3 22.1 2.7e-22 78.9 8.8 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 KLO17846.1 - 0.00017 21.4 6.1 0.0017 18.1 0.1 2.3 2 0 0 2 2 2 2 Putative manganese efflux pump TerC PF03741.16 KLO17846.1 - 0.016 14.9 4.7 0.036 13.7 0.1 2.4 2 0 0 2 2 2 0 Integral membrane protein TerC family YIEGIA PF14045.6 KLO17846.1 - 0.067 12.0 0.1 0.15 10.9 0.1 1.5 1 0 0 1 1 1 0 YIEGIA protein DUF3995 PF13160.6 KLO17846.1 - 0.85 10.0 10.3 0.48 10.8 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) G3P_acyltransf PF02660.15 KLO17846.1 - 4.5 7.3 13.9 0.23 11.5 4.0 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase Lactamase_B PF00753.27 KLO17847.1 - 1.5e-07 31.6 0.0 2.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KLO17847.1 - 2.8e-07 30.3 0.4 7.5e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KLO17847.1 - 0.1 12.3 0.1 0.36 10.5 0.1 2.0 1 1 0 1 1 1 0 tRNase Z endonuclease ArAE_2 PF10334.9 KLO17848.1 - 1.8e-54 185.0 0.0 4e-54 183.9 0.0 1.6 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 KLO17848.1 - 6.7e-46 157.3 5.2 8.8e-45 153.6 2.3 3.1 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KLO17848.1 - 1.3e-09 38.2 9.1 1.3e-09 38.2 9.1 3.4 3 0 0 3 3 3 1 Fusaric acid resistance protein-like Gate PF07670.14 KLO17848.1 - 0.0089 16.3 1.1 0.028 14.7 0.0 2.3 2 1 0 2 2 2 1 Nucleoside recognition V-SNARE PF05008.15 KLO17852.1 - 1.7e-21 76.3 3.5 1.7e-21 76.3 3.5 2.3 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KLO17852.1 - 8.6e-16 58.0 4.6 8.6e-16 58.0 4.6 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KLO17852.1 - 0.035 14.0 0.6 0.087 12.7 0.1 1.9 2 0 0 2 2 2 0 Sec20 Exonuc_VII_L PF02601.15 KLO17852.1 - 0.047 13.2 8.4 0.26 10.8 8.4 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit RmuC PF02646.16 KLO17852.1 - 0.19 10.9 5.0 0.27 10.3 0.2 2.2 2 0 0 2 2 2 0 RmuC family DUF241 PF03087.14 KLO17852.1 - 0.27 11.1 5.9 0.082 12.7 0.9 2.0 1 1 1 2 2 2 0 Arabidopsis protein of unknown function CC2-LZ PF16516.5 KLO17852.1 - 0.67 10.4 7.2 1 9.8 1.2 2.9 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF883 PF05957.13 KLO17852.1 - 0.7 10.5 11.9 1.7 9.3 0.6 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) NPBW PF15180.6 KLO17852.1 - 0.71 9.7 4.7 17 5.3 0.0 3.1 2 1 1 3 3 3 0 Neuropeptides B and W COG2 PF06148.11 KLO17852.1 - 0.91 9.6 5.4 18 5.4 2.0 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Filament PF00038.21 KLO17852.1 - 1.1 8.7 11.1 0.43 10.1 4.6 2.2 2 1 0 2 2 2 0 Intermediate filament protein YkyA PF10368.9 KLO17852.1 - 1.5 8.4 7.4 1.3 8.6 3.7 2.1 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Prominin PF05478.11 KLO17852.1 - 1.7 6.5 3.3 8.9 4.1 3.3 1.9 1 1 0 1 1 1 0 Prominin SNARE PF05739.19 KLO17852.1 - 2.5 8.2 9.1 2.9 7.9 2.7 3.0 2 1 0 2 2 2 0 SNARE domain YqjK PF13997.6 KLO17852.1 - 3.8 7.8 6.6 0.46 10.8 0.8 2.4 2 1 1 3 3 2 0 YqjK-like protein Plasmid_RAQPRD PF09686.10 KLO17852.1 - 4.7 7.5 8.9 13 6.1 0.1 2.8 3 0 0 3 3 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Prefoldin_2 PF01920.20 KLO17853.1 - 1.1e-19 70.4 11.0 1.3e-19 70.1 11.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit SOGA PF11365.8 KLO17853.1 - 0.0007 20.7 3.5 0.0024 19.0 3.5 1.8 1 1 0 1 1 1 1 Protein SOGA FPP PF05911.11 KLO17853.1 - 0.0031 15.8 6.3 0.0035 15.6 6.3 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Alb1 PF09135.11 KLO17853.1 - 0.021 15.7 4.0 0.039 14.8 3.7 1.6 1 1 0 1 1 1 0 Alb1 DUF4372 PF14294.6 KLO17853.1 - 0.06 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) DUF4349 PF14257.6 KLO17853.1 - 0.082 12.3 4.6 0.26 10.7 4.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Tmpp129 PF10272.9 KLO17853.1 - 0.12 11.6 0.8 0.19 11.0 0.5 1.4 1 1 0 1 1 1 0 Putative transmembrane protein precursor APG6_N PF17675.1 KLO17853.1 - 0.3 11.6 6.3 2.6 8.6 1.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 KLO17853.1 - 0.44 10.6 7.9 0.79 9.8 7.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DMPK_coil PF08826.10 KLO17853.1 - 0.55 10.4 7.5 1.6 8.9 0.9 2.5 2 1 0 2 2 2 0 DMPK coiled coil domain like Rx_N PF18052.1 KLO17853.1 - 0.67 10.3 4.5 0.38 11.1 0.6 2.0 1 1 1 2 2 2 0 Rx N-terminal domain ADIP PF11559.8 KLO17853.1 - 0.86 9.7 9.6 4.2 7.4 0.8 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 KLO17853.1 - 1.4 9.4 6.7 0.35 11.3 0.9 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) YkyA PF10368.9 KLO17853.1 - 1.7 8.3 11.6 6.5 6.4 8.9 2.1 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein DHR10 PF18595.1 KLO17853.1 - 2.4 8.3 11.7 22 5.1 11.7 2.0 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain XhlA PF10779.9 KLO17853.1 - 2.6 8.3 7.4 13 6.1 1.0 2.4 2 1 0 2 2 2 0 Haemolysin XhlA DUF16 PF01519.16 KLO17853.1 - 5 7.7 10.4 0.89 10.1 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Ribosomal_S17 PF00366.20 KLO17854.1 - 9.8e-20 70.4 0.7 1.2e-19 70.1 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Vac_Fusion PF02346.16 KLO17854.1 - 0.029 14.0 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 Ribosomal_L37e PF01907.19 KLO17859.1 - 0.0077 16.4 0.9 0.0077 16.4 0.9 2.0 3 0 0 3 3 3 1 Ribosomal protein L37e Fasciclin PF02469.22 KLO17860.1 - 1.9e-34 118.7 9.0 8e-23 81.1 1.4 2.2 2 0 0 2 2 2 2 Fasciclin domain Mpv17_PMP22 PF04117.12 KLO17863.1 - 5.2e-22 77.8 0.6 1.2e-21 76.7 0.6 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Fasciclin PF02469.22 KLO17864.1 - 6.6e-32 110.4 0.1 2.3e-23 82.8 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain CBP_BcsR PF10945.8 KLO17868.1 - 0.035 13.6 0.0 0.4 10.2 0.0 2.5 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsR PmrD PF11183.8 KLO17879.1 - 0.025 14.7 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD Helicase_RecD PF05127.14 KLO17882.1 - 0.069 13.0 0.0 0.71 9.7 0.0 2.1 2 0 0 2 2 2 0 Helicase Gpr1_Fun34_YaaH PF01184.19 KLO17883.1 - 2.1e-79 265.9 18.3 2.7e-79 265.6 18.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF4181 PF13789.6 KLO17883.1 - 0.22 11.8 3.6 0.11 12.8 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DUF2070 PF09843.9 KLO17883.1 - 0.23 9.7 8.3 0.27 9.5 8.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DdrB PF12747.7 KLO17884.1 - 0.088 12.6 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 DdrB-like protein XhlA PF10779.9 KLO17890.1 - 0.0063 16.7 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Haemolysin XhlA FmiP_Thoc5 PF09766.9 KLO17890.1 - 0.045 13.0 0.0 0.054 12.8 0.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 FOXP-CC PF16159.5 KLO17890.1 - 0.11 13.2 0.5 0.28 11.8 0.5 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain Vac_Fusion PF02346.16 KLO17890.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 HGTP_anticodon PF03129.20 KLO17893.1 - 8.9e-21 73.9 0.0 2.5e-20 72.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KLO17893.1 - 2.5e-09 37.4 0.0 5.7e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TAL_FSA PF00923.19 KLO17894.1 - 1.1e-93 313.7 0.0 1.2e-93 313.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Glyco_hydro_12 PF01670.16 KLO17895.1 - 1.2e-35 123.5 10.7 1.4e-35 123.2 10.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Ribosomal_L24e PF01246.20 KLO17896.1 - 2.1e-29 101.6 0.1 2.1e-29 101.6 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Synaptobrevin PF00957.21 KLO17897.1 - 1.4e-24 85.7 0.9 1.8e-24 85.4 0.9 1.1 1 0 0 1 1 1 1 Synaptobrevin Prominin PF05478.11 KLO17897.1 - 0.026 12.5 0.0 0.033 12.2 0.0 1.0 1 0 0 1 1 1 0 Prominin DUF515 PF04415.12 KLO17897.1 - 0.053 11.9 1.2 0.068 11.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF3899 PF13038.6 KLO17897.1 - 0.055 14.0 0.1 0.079 13.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) SKG6 PF08693.10 KLO17898.1 - 0.00011 21.5 0.7 0.00026 20.3 0.7 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KLO17898.1 - 0.00057 20.0 0.3 0.0017 18.5 0.1 2.0 2 0 0 2 2 2 1 Podoplanin SprB PF13573.6 KLO17898.1 - 0.0044 16.8 0.2 0.0044 16.8 0.2 2.1 2 0 0 2 2 2 1 SprB repeat CoatB PF10389.9 KLO17898.1 - 0.046 13.6 1.7 0.069 13.0 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage coat protein B Herpes_gE PF02480.16 KLO17898.1 - 0.054 12.2 0.0 0.093 11.5 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM51 PF15345.6 KLO17898.1 - 0.067 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 VPDSG-CTERM PF18205.1 KLO17898.1 - 2 8.3 6.8 3.4 7.6 5.7 2.1 1 1 1 2 2 2 0 VPDSG-CTERM motif MAP65_ASE1 PF03999.12 KLO17899.1 - 4.1e-69 233.9 14.3 2.4e-67 228.0 5.3 2.7 2 1 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) TSC22 PF01166.18 KLO17899.1 - 0.19 12.1 5.2 0.22 11.9 0.3 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family Carbpep_Y_N PF05388.11 KLO17899.1 - 0.28 11.7 4.0 0.44 11.1 1.3 2.6 2 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide Exonuc_VII_L PF02601.15 KLO17899.1 - 0.3 10.6 6.6 0.48 10.0 0.3 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit SF-assemblin PF06705.11 KLO17899.1 - 0.34 10.2 6.9 0.18 11.2 1.7 2.8 3 0 0 3 3 3 0 SF-assemblin/beta giardin Mvb12 PF09452.10 KLO17899.1 - 0.37 11.2 3.2 3.9 8.0 0.1 3.2 3 0 0 3 3 3 0 ESCRT-I subunit Mvb12 SAM_KSR1 PF13543.6 KLO17899.1 - 0.56 10.4 5.1 17 5.6 1.0 3.2 2 1 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Terminase_4 PF05119.12 KLO17899.1 - 1.7 9.1 5.6 54 4.3 0.1 4.3 4 1 1 5 5 5 0 Phage terminase, small subunit FliJ PF02050.16 KLO17899.1 - 2.9 8.1 10.2 0.21 11.8 0.7 2.9 2 1 0 2 2 2 0 Flagellar FliJ protein Pkinase PF00069.25 KLO17900.1 - 2e-72 243.7 0.0 3.1e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO17900.1 - 4.9e-39 134.2 0.0 7.1e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO17900.1 - 1.5e-09 37.6 0.0 2.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO17900.1 - 0.021 14.2 0.2 0.041 13.2 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KLO17900.1 - 0.1 11.5 0.0 0.33 9.8 0.0 1.8 1 0 0 1 1 1 0 Haspin like kinase domain DUF1744 PF08490.12 KLO17901.1 - 1.5e-131 438.7 0.0 2.2e-131 438.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KLO17901.1 - 4e-59 200.4 0.0 6.8e-59 199.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KLO17901.1 - 2.6e-12 46.2 0.6 2.4e-06 26.5 0.0 3.8 3 1 0 3 3 3 3 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KLO17901.1 - 1.3e-07 31.5 0.5 1.2e-06 28.4 0.3 2.5 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KLO17901.1 - 0.00016 21.7 0.0 0.00061 19.8 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily ArsC PF03960.15 KLO17901.1 - 0.012 15.7 0.1 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 ArsC family Skp1_POZ PF03931.15 KLO17902.1 - 1.6e-05 24.9 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Pkinase_Tyr PF07714.17 KLO17904.1 - 5e-39 134.1 0.0 6.9e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO17904.1 - 3.3e-34 118.4 0.0 4.2e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KLO17904.1 - 9.3e-05 21.4 0.0 0.00013 20.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO17904.1 - 0.0034 16.7 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO17904.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KLO17904.1 - 0.099 12.5 0.0 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family WH1 PF00568.23 KLO17905.1 - 8.6e-24 83.6 0.0 1.2e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 KLO17905.1 - 8.6e-08 32.4 0.1 2.1e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 KLO17905.1 - 0.00067 19.4 0.0 0.0019 18.0 0.0 1.8 1 0 0 1 1 1 1 WH2 motif Glyco_hydro_11 PF00457.17 KLO17906.1 - 2.3e-79 265.2 15.8 2.9e-79 264.8 15.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 KLO17906.1 - 1.9e-11 43.7 8.6 6e-11 42.1 8.6 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain CarboxypepD_reg PF13620.6 KLO17906.1 - 0.1 12.9 6.0 0.98 9.7 0.3 2.6 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain CENP-T_C PF15511.6 KLO17907.1 - 4.9e-07 29.9 0.0 5.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KLO17907.1 - 3.4e-05 23.9 0.1 4.8e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KLO17907.1 - 0.0002 21.6 0.0 0.00026 21.3 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KLO17907.1 - 0.00085 19.6 0.1 0.0016 18.7 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KLO17907.1 - 0.00094 19.5 0.2 0.0011 19.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KLO17907.1 - 0.058 13.5 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KLO17907.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KLO17908.1 - 2.1e-49 167.2 3.5 2.4e-49 167.1 3.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KLO17908.1 - 2e-05 24.6 0.1 3.6e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KLO17908.1 - 4.7e-05 23.7 0.0 7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KLO17908.1 - 0.00052 20.6 2.4 0.00068 20.2 2.4 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KLO17908.1 - 0.0033 17.7 0.1 0.0059 16.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone F-box-like PF12937.7 KLO17909.1 - 1.4e-07 31.3 1.2 1.4e-07 31.3 1.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO17909.1 - 0.0014 18.4 0.4 0.0014 18.4 0.4 2.5 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KLO17909.1 - 0.03 14.2 0.1 0.03 14.2 0.1 2.1 2 0 0 2 2 2 0 F-box YkuI_C PF10388.9 KLO17909.1 - 0.23 11.2 0.1 0.41 10.4 0.1 1.3 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain RhoGAP PF00620.27 KLO17910.1 - 6.3e-47 159.2 0.0 1.2e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KLO17910.1 - 7.6e-14 51.8 1.4 1.3e-13 51.0 0.1 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PCRF PF03462.18 KLO17910.1 - 0.0055 16.6 1.7 0.011 15.6 1.7 1.5 1 0 0 1 1 1 1 PCRF domain DUF745 PF05335.13 KLO17910.1 - 0.015 15.1 5.0 0.031 14.0 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) SKA2 PF16740.5 KLO17910.1 - 0.084 12.7 2.6 0.29 10.9 2.6 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Exonuc_VII_L PF02601.15 KLO17910.1 - 0.11 12.0 2.2 0.21 11.1 2.2 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.11 KLO17910.1 - 0.26 11.6 0.7 0.81 10.0 0.7 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 KLO17910.1 - 0.59 10.2 5.0 1.2 9.2 5.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FAM184 PF15665.5 KLO17910.1 - 1.4 8.7 12.8 0.73 9.6 10.4 1.8 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DivIC PF04977.15 KLO17910.1 - 2.1 8.1 6.2 2.6 7.9 4.5 2.0 2 0 0 2 2 2 0 Septum formation initiator Nucleopor_Nup85 PF07575.13 KLO17911.1 - 4.6e-59 200.5 0.0 1.9e-38 132.4 0.0 2.0 2 0 0 2 2 2 2 Nup85 Nucleoporin Opi1 PF08618.10 KLO17912.1 - 1e-110 370.9 9.6 1.7e-83 281.2 2.9 3.4 3 1 1 4 4 4 2 Transcription factor Opi1 REF PF05755.12 KLO17912.1 - 0.15 11.9 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) GATA PF00320.27 KLO17913.1 - 8.5e-30 102.1 15.7 3.7e-15 55.2 5.1 2.7 2 0 0 2 2 2 2 GATA zinc finger Auto_anti-p27 PF06677.12 KLO17913.1 - 0.00068 19.7 4.7 0.28 11.4 0.5 2.6 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.12 KLO17913.1 - 0.00086 18.8 7.3 0.087 12.3 0.7 2.9 3 0 0 3 3 3 2 TFIIB zinc-binding ArfGap PF01412.18 KLO17913.1 - 0.0019 18.2 3.9 0.8 9.8 0.2 2.7 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf GREB1 PF15782.5 KLO17913.1 - 0.17 9.0 0.7 0.31 8.1 0.7 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zn-ribbon_8 PF09723.10 KLO17913.1 - 0.24 11.5 2.3 4.6 7.4 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-RRN7 PF11781.8 KLO17913.1 - 0.46 10.2 5.8 0.59 9.9 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 APG17 PF04108.12 KLO17914.1 - 0.055 12.6 4.6 0.51 9.4 0.7 2.2 2 0 0 2 2 2 0 Autophagy protein Apg17 Lipase_2 PF01674.18 KLO17914.1 - 0.082 12.4 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 Lipase (class 2) DUF2884 PF11101.8 KLO17914.1 - 0.72 9.3 6.0 12 5.3 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DHR10 PF18595.1 KLO17914.1 - 7.1 6.7 12.9 0.6 10.2 1.0 2.8 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Methyltransf_16 PF10294.9 KLO17915.1 - 1.8e-27 96.2 0.0 2.7e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KLO17915.1 - 0.0062 16.4 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO17915.1 - 0.054 14.3 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Rhomboid PF01694.22 KLO17916.1 - 3.3e-18 66.1 9.1 3.3e-18 66.1 9.1 2.0 2 1 0 2 2 2 1 Rhomboid family Methyltransf_16 PF10294.9 KLO17917.1 - 7.1e-16 58.4 0.0 3.1e-14 53.1 0.0 2.3 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KLO17917.1 - 0.0043 16.9 0.0 0.0053 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KLO17917.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Asp PF00026.23 KLO17919.1 - 3.8e-73 246.6 1.7 4.6e-73 246.4 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO17919.1 - 5.3e-12 46.3 1.6 6.9e-06 26.4 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KLO17919.1 - 0.04 13.7 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Histone PF00125.24 KLO17920.1 - 2.1e-49 167.2 3.5 2.4e-49 167.1 3.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KLO17920.1 - 2e-05 24.6 0.1 3.6e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KLO17920.1 - 4.7e-05 23.7 0.0 7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KLO17920.1 - 0.00052 20.6 2.4 0.00068 20.2 2.4 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KLO17920.1 - 0.0033 17.7 0.1 0.0059 16.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KLO17921.1 - 4.9e-07 29.9 0.0 5.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KLO17921.1 - 3.4e-05 23.9 0.1 4.8e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KLO17921.1 - 0.0002 21.6 0.0 0.00026 21.3 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KLO17921.1 - 0.00085 19.6 0.1 0.0016 18.7 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KLO17921.1 - 0.00094 19.5 0.2 0.0011 19.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KLO17921.1 - 0.058 13.5 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KLO17921.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated p450 PF00067.22 KLO17922.1 - 4.7e-57 193.8 0.0 6.2e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Egh16-like PF11327.8 KLO17923.1 - 4.6e-53 180.4 12.7 5.2e-53 180.2 12.7 1.0 1 0 0 1 1 1 1 Egh16-like virulence factor I-set PF07679.16 KLO17923.1 - 0.042 13.9 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain DUF2015 PF09435.10 KLO17925.1 - 1.1e-35 121.9 0.0 1.3e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Smr PF01713.21 KLO17926.1 - 2.6e-07 30.9 0.0 7.5e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 KLO17926.1 - 0.00025 21.3 4.2 0.00053 20.3 4.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Virul_fac_BrkB PF03631.15 KLO17927.1 - 0.00029 20.5 0.6 0.00042 20.0 0.6 1.2 1 0 0 1 1 1 1 Virulence factor BrkB DUF2207 PF09972.9 KLO17927.1 - 0.0011 17.8 0.2 0.0014 17.5 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Bacillus_HBL PF05791.11 KLO17927.1 - 0.075 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) E1-E2_ATPase PF00122.20 KLO17927.1 - 0.092 12.3 0.7 0.14 11.7 0.7 1.2 1 0 0 1 1 1 0 E1-E2 ATPase baeRF_family11 PF18855.1 KLO17927.1 - 0.17 12.2 0.0 16 5.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 11 DUF4229 PF14012.6 KLO17927.1 - 1.1 9.4 4.4 2.9 8.0 4.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF98 PF01947.16 KLO17928.1 - 0.0015 18.5 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 p-hydroxybenzoic acid synthase Gar1 PF04410.14 KLO17928.1 - 0.098 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region zf-C2HC5 PF06221.13 KLO17929.1 - 5.1e-15 55.2 6.9 7.4e-15 54.7 6.9 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type BLOC1S3 PF15753.5 KLO17930.1 - 0.086 13.0 0.4 5.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 GhoS PF11080.8 KLO17931.1 - 0.18 11.8 0.1 1.9 8.6 0.1 2.1 1 1 0 1 1 1 0 Endoribonuclease GhoS adh_short_C2 PF13561.6 KLO17932.1 - 1.8e-50 171.7 0.0 2.3e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO17932.1 - 8.1e-38 129.8 0.0 1e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO17932.1 - 2.4e-08 34.1 0.0 3.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KLO17932.1 - 0.016 14.6 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KLO17932.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RhoGAP PF00620.27 KLO17933.1 - 3.3e-43 147.1 0.0 5.8e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KLO17933.1 - 7.7e-16 58.5 0.0 1.8e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 PH domain PX PF00787.24 KLO17933.1 - 7.8e-08 32.3 0.0 1.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 PX domain PH_8 PF15409.6 KLO17933.1 - 0.0063 16.8 0.0 0.023 15.0 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain SDH_alpha PF03313.15 KLO17934.1 - 2.1e-101 339.0 0.4 2.6e-101 338.7 0.4 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 KLO17934.1 - 3.5e-58 196.4 0.0 6.4e-58 195.5 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain Ras PF00071.22 KLO17935.1 - 4.8e-51 172.6 0.0 6.1e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO17935.1 - 5.2e-20 71.9 0.0 7.4e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO17935.1 - 1.9e-06 27.4 0.0 2.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KLO17935.1 - 0.014 15.3 0.0 3.2 7.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KLO17935.1 - 0.024 14.0 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KLO17935.1 - 0.024 14.1 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KLO17935.1 - 0.026 14.6 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase HPS3_Mid PF14762.6 KLO17935.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region Sugar_tr PF00083.24 KLO17936.1 - 4.7e-126 421.3 24.2 5.5e-126 421.1 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO17936.1 - 1e-21 77.3 44.9 6.4e-20 71.4 28.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 KLO17938.1 - 0.00026 20.8 4.6 0.0013 18.6 4.6 2.3 1 1 0 1 1 1 1 F-box-like DEAD PF00270.29 KLO17940.1 - 5.7e-42 143.4 0.0 2.2e-41 141.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO17940.1 - 9.1e-27 93.6 0.3 1.3e-25 89.9 0.0 2.8 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO17940.1 - 4.1e-07 30.2 0.2 7.7e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2608 PF11019.8 KLO17940.1 - 0.08 12.4 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Clathrin PF00637.20 KLO17941.1 - 3.3e-206 675.5 36.4 6.5e-33 113.6 0.2 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KLO17941.1 - 3.5e-32 109.1 0.2 4.8e-07 29.8 0.0 6.8 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin_H_link PF13838.6 KLO17941.1 - 5.2e-30 103.2 1.2 1.6e-29 101.6 0.1 2.6 3 0 0 3 3 3 1 Clathrin-H-link Clathrin-link PF09268.10 KLO17941.1 - 1.8e-11 43.2 2.1 2.6e-11 42.7 0.0 2.5 3 0 0 3 3 3 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KLO17941.1 - 0.0002 20.6 5.3 1.2 8.1 0.1 4.7 4 0 0 4 4 4 2 Coatomer WD associated region TPR_1 PF00515.28 KLO17941.1 - 0.0072 16.1 0.8 50 3.9 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KLO17941.1 - 0.022 14.8 3.4 31 4.9 0.2 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KLO17941.1 - 0.032 14.4 5.9 67 4.0 0.2 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 KLO17941.1 - 0.032 14.5 1.1 78 3.9 0.0 5.5 6 0 0 6 6 6 0 PPR repeat Acetyltransf_15 PF17013.5 KLO17941.1 - 0.035 13.6 0.2 0.18 11.2 0.0 2.3 2 0 0 2 2 2 0 Putative acetyl-transferase Vps39_1 PF10366.9 KLO17941.1 - 0.12 12.7 10.8 3.6 7.9 0.1 6.3 6 2 2 8 8 8 0 Vacuolar sorting protein 39 domain 1 TPR_14 PF13428.6 KLO17941.1 - 0.19 12.6 10.0 1.6e+02 3.5 0.1 7.6 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 KLO17941.1 - 3.1 8.2 11.7 7.7 7.0 0.0 6.1 8 0 0 8 8 6 0 Tetratricopeptide repeat PQ-loop PF04193.14 KLO17942.1 - 3.4e-16 58.8 11.4 1.2e-12 47.4 2.6 2.8 3 0 0 3 3 3 2 PQ loop repeat ubiquitin PF00240.23 KLO17943.1 - 2.1e-33 113.9 0.5 4.3e-33 112.9 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KLO17943.1 - 5.3e-25 87.3 1.9 5.3e-25 87.3 1.9 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KLO17943.1 - 2e-15 56.4 0.5 4.3e-15 55.3 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KLO17943.1 - 2.8e-05 24.5 0.6 0.0002 21.7 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KLO17943.1 - 0.0051 16.9 0.5 0.012 15.7 0.5 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KLO17943.1 - 0.0059 16.5 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KLO17943.1 - 0.0081 16.5 0.6 0.017 15.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 KLO17943.1 - 0.0082 16.7 0.6 0.011 16.2 0.6 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.21 KLO17943.1 - 0.011 15.9 0.4 0.018 15.2 0.4 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 KLO17943.1 - 0.021 14.9 1.0 6 7.0 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 KLO17943.1 - 0.059 13.2 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Rep_fac_C PF08542.11 KLO17944.1 - 2.4e-18 66.3 0.0 1.3e-17 64.0 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 KLO17944.1 - 7.5e-18 65.2 0.0 1.2e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KLO17944.1 - 7.9e-15 55.0 0.0 1.2e-10 41.4 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KLO17944.1 - 1.2e-09 38.4 0.0 4.3e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain DUF815 PF05673.13 KLO17944.1 - 2.7e-06 26.7 0.0 4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 KLO17944.1 - 2.9e-06 27.1 0.0 1.2e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KLO17944.1 - 9.7e-06 25.5 0.1 0.00017 21.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KLO17944.1 - 1.5e-05 25.1 0.2 5e-05 23.3 0.1 1.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO17944.1 - 3.2e-05 24.4 0.0 7.3e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 KLO17944.1 - 3.2e-05 24.2 0.0 0.00012 22.4 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain ResIII PF04851.15 KLO17944.1 - 0.00013 22.0 0.0 0.011 15.8 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 KLO17944.1 - 0.00014 21.6 0.0 0.00024 20.9 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KLO17944.1 - 0.00017 21.9 0.1 0.04 14.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 KLO17944.1 - 0.00018 21.3 0.0 0.00088 19.1 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KLO17944.1 - 0.00019 21.7 0.8 0.061 13.6 0.5 2.9 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 KLO17944.1 - 0.0003 20.6 0.4 0.0012 18.6 0.6 1.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_5 PF07728.14 KLO17944.1 - 0.00033 20.7 0.1 0.0034 17.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KLO17944.1 - 0.0004 20.2 0.0 0.00074 19.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KLO17944.1 - 0.00084 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KLO17944.1 - 0.0029 17.1 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 KLO17944.1 - 0.0036 16.7 0.1 0.11 11.9 0.1 2.2 1 1 1 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 KLO17944.1 - 0.0095 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KLO17944.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KLO17944.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KLO17944.1 - 0.028 13.5 0.0 0.067 12.2 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Methyltransf_31 PF13847.6 KLO17944.1 - 0.03 14.1 0.1 0.076 12.8 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain MCM PF00493.23 KLO17944.1 - 0.044 12.9 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_28 PF13521.6 KLO17944.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.23 KLO17944.1 - 0.068 11.9 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Mg_chelatase PF01078.21 KLO17944.1 - 0.073 12.4 0.0 0.39 10.1 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 KLO17944.1 - 0.075 12.2 0.1 1.8 7.7 0.1 2.1 1 1 1 2 2 2 0 PIF1-like helicase AAA_25 PF13481.6 KLO17944.1 - 0.13 11.8 0.0 0.81 9.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain Zw10 PF06248.13 KLO17945.1 - 3.1e-27 95.4 2.8 3.5e-24 85.3 0.4 2.8 3 1 0 3 3 3 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 KLO17945.1 - 6.8e-08 32.5 0.3 4.8e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal DUF4363 PF14276.6 KLO17945.1 - 0.05 13.7 1.2 0.18 11.9 1.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Sigma54_activ_2 PF14532.6 KLO17945.1 - 0.12 12.4 2.6 2.9 8.0 0.0 4.0 5 0 0 5 5 5 0 Sigma-54 interaction domain Exonuc_VII_L PF02601.15 KLO17945.1 - 0.24 10.9 6.4 0.22 11.0 4.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Cep57_CLD_2 PF14197.6 KLO17945.1 - 0.3 11.2 1.8 3.3 7.8 0.9 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.12 KLO17945.1 - 0.47 10.5 4.5 0.41 10.7 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TPR_19 PF14559.6 KLO17946.1 - 2.5e-05 24.7 3.7 0.019 15.4 0.8 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KLO17946.1 - 0.006 17.2 3.5 4.9 7.9 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO17946.1 - 0.014 15.5 0.0 8.9 6.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 KLO17946.1 - 0.023 13.9 0.8 0.15 11.2 0.7 2.1 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KLO17946.1 - 0.05 14.4 2.2 11 7.1 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO17946.1 - 0.087 13.1 0.0 11 6.3 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KLO17946.1 - 0.19 11.9 0.2 32 4.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MBOAT PF03062.19 KLO17947.1 - 3.8e-39 135.0 19.7 3.9e-38 131.7 11.4 2.9 2 2 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KLO17947.1 - 0.0031 17.7 4.2 0.004 17.4 1.7 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Fumarate_red_D PF02313.17 KLO17947.1 - 1.5 9.0 11.5 0.037 14.1 2.9 2.4 3 0 0 3 3 3 0 Fumarate reductase subunit D RED_N PF07808.13 KLO17948.1 - 5.8e-14 52.2 10.0 5.8e-14 52.2 10.0 3.3 3 1 1 4 4 4 1 RED-like protein N-terminal region MMgT PF10270.9 KLO17949.1 - 1.9e-15 57.0 0.0 2.3e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter DUF1624 PF07786.12 KLO17949.1 - 0.09 12.3 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Gyro_capsid PF04162.12 KLO17951.1 - 0.079 11.4 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) TRAUB PF08164.12 KLO17952.1 - 1.8e-27 95.6 1.3 1.1e-26 93.1 0.0 2.8 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KLO17952.1 - 3.5e-21 76.4 0.1 3.5e-21 76.4 0.1 2.5 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor DUF1676 PF07898.13 KLO17952.1 - 7 6.7 6.4 11 6.1 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Peptidase_A17 PF05380.13 KLO17953.1 - 0.076 13.0 0.8 0.13 12.2 0.8 1.3 1 0 0 1 1 1 0 Pao retrotransposon peptidase NIR_SIR PF01077.22 KLO17954.1 - 2.6e-50 170.0 0.0 1.6e-46 157.7 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KLO17954.1 - 4.5e-30 103.3 0.1 9.6e-16 57.4 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KLO17954.1 - 1.8e-26 93.0 0.0 3.5e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 KLO17954.1 - 0.0019 18.0 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_5 PF12724.7 KLO17954.1 - 0.0049 17.1 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin domain DUF4515 PF14988.6 KLO17955.1 - 0.011 15.6 0.0 0.013 15.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) LOH1CR12 PF10158.9 KLO17955.1 - 0.071 13.1 0.0 0.08 13.0 0.0 1.1 1 0 0 1 1 1 0 Tumour suppressor protein adh_short_C2 PF13561.6 KLO17956.1 - 5e-42 144.1 0.6 2.4e-39 135.3 0.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO17956.1 - 1.1e-39 135.9 2.3 7.2e-39 133.3 2.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO17956.1 - 2.6e-08 34.0 0.2 1.3e-07 31.7 0.2 1.9 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KLO17956.1 - 0.0053 16.2 0.1 0.0096 15.4 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KLO17956.1 - 0.015 14.8 0.1 0.045 13.2 0.1 1.8 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 KLO17956.1 - 0.054 14.1 0.2 0.13 12.8 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Clr2_transil PF16761.5 KLO17957.1 - 2.5e-25 89.1 0.6 4.4e-25 88.3 0.6 1.4 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KLO17957.1 - 5.6e-11 43.4 0.0 2.8e-10 41.1 0.0 2.3 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 KAR9 PF08580.10 KLO17958.1 - 1.6e-22 79.9 40.9 1.6e-22 79.9 40.9 3.5 2 1 1 3 3 3 1 Yeast cortical protein KAR9 GAS2 PF02187.17 KLO17958.1 - 3.7e-05 23.7 0.0 9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain YgaB PF14182.6 KLO17958.1 - 0.063 13.7 0.4 16 6.0 0.0 2.6 2 0 0 2 2 2 0 YgaB-like protein DUF1515 PF07439.11 KLO17958.1 - 0.37 10.8 2.1 0.47 10.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) PX PF00787.24 KLO17960.1 - 3.5e-20 72.1 0.0 8.5e-20 70.8 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KLO17960.1 - 1.5e-06 27.9 2.8 0.0038 16.8 0.3 2.2 2 0 0 2 2 2 2 Vps5 C terminal like AAA_33 PF13671.6 KLO17961.1 - 3.6e-11 43.4 0.1 0.00026 21.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 KLO17961.1 - 6.5e-05 23.5 0.0 0.0001 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.11 KLO17961.1 - 0.0015 18.6 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_16 PF13191.6 KLO17961.1 - 0.0025 18.2 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KLO17961.1 - 0.032 13.7 0.0 0.22 11.0 0.1 1.9 1 1 1 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KLO17961.1 - 0.043 13.1 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 KLO17961.1 - 0.051 13.5 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 KLO17961.1 - 0.053 13.8 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KLO17961.1 - 0.062 13.1 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase ATP_bind_1 PF03029.17 KLO17961.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 KLO17961.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PmoA PF14100.6 KLO17961.1 - 0.14 11.6 0.0 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 Methane oxygenase PmoA Mg_chelatase PF01078.21 KLO17961.1 - 0.18 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 KLO17961.1 - 0.25 10.5 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit TPR_11 PF13414.6 KLO17962.1 - 1.5e-16 59.8 2.2 3.2e-06 26.7 0.0 4.6 2 2 3 5 5 5 4 TPR repeat TPR_1 PF00515.28 KLO17962.1 - 3.2e-15 55.2 0.2 1.1e-06 28.2 0.0 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO17962.1 - 1.4e-14 53.0 1.1 2.8e-06 27.0 0.0 5.3 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KLO17962.1 - 2.2e-12 47.4 0.5 0.00063 20.3 0.1 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KLO17962.1 - 1.6e-11 44.0 1.8 0.0006 20.4 0.0 4.4 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KLO17962.1 - 4.2e-11 42.4 0.1 0.036 14.4 0.0 3.9 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KLO17962.1 - 1.8e-10 41.2 0.6 0.00043 20.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KLO17962.1 - 4.3e-09 36.5 2.0 0.0067 16.7 0.0 3.6 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KLO17962.1 - 4.8e-08 32.6 0.3 0.05 13.8 0.0 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KLO17962.1 - 1.2e-05 25.0 3.9 0.35 11.0 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KLO17962.1 - 1.2e-05 24.6 0.0 1.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KLO17962.1 - 2.3e-05 24.8 0.2 0.022 15.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KLO17962.1 - 4.8e-05 23.1 5.7 0.34 10.9 0.0 3.9 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KLO17962.1 - 0.00026 21.1 0.1 0.13 12.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 KLO17962.1 - 0.00028 21.2 1.0 0.25 12.1 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO17962.1 - 0.0014 18.8 0.1 0.11 12.7 0.0 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KLO17962.1 - 0.004 17.5 0.2 0.14 12.5 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 KLO17962.1 - 0.0058 16.7 0.5 1.5 8.9 0.1 3.2 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain BTAD PF03704.17 KLO17962.1 - 0.0059 17.1 0.7 0.36 11.3 0.1 2.7 1 1 1 2 2 2 1 Bacterial transcriptional activator domain DUF3856 PF12968.7 KLO17962.1 - 0.0091 16.1 0.3 2.1 8.4 0.0 2.6 1 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 KLO17962.1 - 0.038 14.1 0.0 0.074 13.1 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Fis1_TPR_C PF14853.6 KLO17962.1 - 0.046 13.8 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Velvet PF11754.8 KLO17963.1 - 4.8e-31 108.6 2.1 1.2e-19 71.3 0.0 2.8 2 1 1 3 3 3 2 Velvet factor Cytochrom_C1 PF02167.15 KLO17964.1 - 6e-98 326.9 0.0 7.4e-98 326.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KLO17964.1 - 0.0013 19.0 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KLO17964.1 - 0.01 17.0 0.2 0.036 15.2 0.1 2.0 2 1 0 2 2 2 0 Cytochrome c SAC3_GANP PF03399.16 KLO17965.1 - 4.7e-25 88.6 8.1 1.8e-23 83.4 8.1 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KLO17965.1 - 3e-10 40.2 0.6 7.7e-10 38.9 0.6 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Myco_haema PF05692.12 KLO17965.1 - 0.0077 15.2 0.1 0.012 14.6 0.1 1.3 1 0 0 1 1 1 1 Mycoplasma haemagglutinin COX5A PF02284.16 KLO17965.1 - 0.054 13.5 0.1 1.6 8.8 0.0 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase subunit Va tRNA_int_endo PF01974.17 KLO17966.1 - 5.5e-18 64.8 0.3 2.1e-17 63.0 0.3 1.9 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KLO17966.1 - 0.00019 21.1 0.1 0.037 13.7 0.1 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain WD40 PF00400.32 KLO17967.1 - 4e-12 46.5 9.8 0.046 14.6 0.5 7.5 7 1 0 7 7 7 4 WD domain, G-beta repeat Com_YlbF PF06133.11 KLO17967.1 - 2.2 8.9 13.4 16 6.1 10.2 2.2 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Aminotran_5 PF00266.19 KLO17968.1 - 4.9e-30 104.7 0.0 6.8e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KLO17968.1 - 0.0045 15.6 0.1 0.008 14.7 0.1 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.19 KLO17968.1 - 0.014 15.5 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain NAPRTase_N PF17767.1 KLO17968.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Amidase PF01425.21 KLO17969.1 - 4.8e-103 345.5 0.0 6.8e-103 345.0 0.0 1.2 1 0 0 1 1 1 1 Amidase RRM_1 PF00076.22 KLO17970.1 - 2.5e-32 110.5 2.1 6.5e-16 57.9 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KLO17970.1 - 1.1e-07 31.6 0.0 0.079 12.8 0.0 3.6 3 0 0 3 3 3 3 Occluded RNA-recognition motif RRM_7 PF16367.5 KLO17970.1 - 0.00013 22.0 0.0 0.058 13.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif RRM_9 PF18444.1 KLO17970.1 - 0.099 12.5 0.0 4.9 7.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif TcpA PF05946.12 KLO17970.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA NIR_SIR PF01077.22 KLO17971.1 - 4.3e-51 172.6 0.1 7.6e-46 155.5 0.0 2.7 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KLO17971.1 - 2e-31 107.7 0.0 7.7e-17 60.9 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KLO17971.1 - 1.4e-27 96.7 0.1 2.9e-27 95.6 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KLO17971.1 - 0.00057 20.1 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain POR_N PF01855.19 KLO17971.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Peripla_BP_6 PF13458.6 KLO17971.1 - 0.052 13.2 0.2 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding protein MTCP1 PF08991.10 KLO17972.1 - 1.5e-06 28.3 1.6 2e-06 27.9 1.6 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KLO17972.1 - 0.00021 21.3 4.8 0.00032 20.8 4.8 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 KLO17972.1 - 0.00023 21.4 3.9 0.00042 20.5 3.9 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Pkinase PF00069.25 KLO17973.1 - 1.3e-71 241.0 0.0 1.8e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO17973.1 - 1.9e-30 106.0 0.0 6.9e-30 104.2 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 KLO17973.1 - 0.013 15.5 0.2 0.028 14.3 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KLO17973.1 - 0.014 14.4 0.1 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 KLO17973.1 - 0.063 12.6 0.2 0.41 9.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Acetyltransf_2 PF00797.17 KLO17974.1 - 6.4e-20 72.0 0.0 1.3e-18 67.7 0.0 2.0 1 1 0 1 1 1 1 N-acetyltransferase DUF3035 PF11233.8 KLO17974.1 - 0.23 11.8 0.7 0.52 10.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) DUF4896 PF16237.5 KLO17975.1 - 3.1 7.7 7.3 1.9 8.4 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4896) zf-RanBP PF00641.18 KLO17977.1 - 1.2e-11 43.7 25.6 0.00027 20.2 2.0 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 KLO17977.1 - 0.0028 17.0 19.7 0.48 9.9 2.2 4.1 3 1 0 3 3 3 3 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 KLO17977.1 - 0.0054 16.7 8.7 0.98 9.5 0.0 3.8 4 0 0 4 4 4 2 Sec23/Sec24 zinc finger NADH-u_ox-rdase PF10785.9 KLO17978.1 - 1.5e-32 112.1 0.6 2.1e-32 111.7 0.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KLO17978.1 - 7.2e-13 48.3 0.0 1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF2530 PF10745.9 KLO17978.1 - 0.081 13.2 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) DnaJ PF00226.31 KLO17979.1 - 9.4e-18 64.1 0.4 2.3e-17 62.9 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain DUF913 PF06025.12 KLO17979.1 - 2.5 7.0 5.7 0.24 10.4 0.7 1.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF913) DnaJ PF00226.31 KLO17980.1 - 1.4e-21 76.3 1.2 2.7e-21 75.4 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4124 PF13511.6 KLO17980.1 - 1.5 9.2 5.4 5.4 7.4 5.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4124) WD40 PF00400.32 KLO17981.1 - 5.5e-06 27.0 7.9 0.079 13.9 0.5 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO17981.1 - 0.0011 19.2 0.1 0.056 13.8 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1192 PF06698.11 KLO17981.1 - 0.11 12.6 0.2 0.33 11.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Fungal_trans PF04082.18 KLO17982.1 - 9.4e-16 57.6 0.0 1.9e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO17982.1 - 2.7e-05 24.2 10.0 5.5e-05 23.2 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 KLO17982.1 - 0.013 15.5 0.0 0.24 11.5 0.0 3.2 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Matrilin_ccoil PF10393.9 KLO17982.1 - 0.061 13.2 0.5 0.12 12.2 0.5 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Glyco_transf_88 PF16849.5 KLO17982.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 88 SH3_1 PF00018.28 KLO17983.1 - 9.2e-18 63.6 2.6 5e-08 32.4 0.2 2.9 2 1 0 2 2 2 2 SH3 domain SAM_2 PF07647.17 KLO17983.1 - 1.5e-14 53.8 0.0 3.1e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KLO17983.1 - 2.1e-13 49.9 1.7 7.4e-06 25.7 0.2 2.7 2 0 0 2 2 2 2 Variant SH3 domain SAM_1 PF00536.30 KLO17983.1 - 3.1e-13 49.9 0.0 6.9e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KLO17983.1 - 9.9e-09 35.7 0.0 1.8e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_2 PF07653.17 KLO17983.1 - 1.5e-07 31.0 0.3 0.00015 21.4 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 KLO17983.1 - 0.026 14.8 3.2 0.54 10.6 0.4 2.7 2 0 0 2 2 2 0 Bacterial SH3 domain KIAA1430 PF13879.6 KLO17983.1 - 0.27 12.0 2.6 0.52 11.1 0.2 2.5 2 1 0 2 2 2 0 KIAA1430 homologue Dus PF01207.17 KLO17984.1 - 7.5e-73 245.3 0.0 8.4e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 KLO17984.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.17 KLO17984.1 - 0.0012 18.7 0.8 0.021 14.6 0.0 2.4 2 1 1 3 3 3 1 SOR/SNZ family NMO PF03060.15 KLO17984.1 - 0.003 17.0 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase G3P_antiterm PF04309.12 KLO17984.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 KLO17984.1 - 0.19 11.1 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Shisa PF13908.6 KLO17985.1 - 1.1 9.4 5.7 2.1 8.6 5.7 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Abhydrolase_4 PF08386.10 KLO17986.1 - 5.1e-18 65.1 0.0 9e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KLO17986.1 - 1.8e-15 57.3 0.0 4.6e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO17986.1 - 0.0007 20.3 0.0 0.0072 16.9 0.0 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO17987.1 - 3.4e-16 59.7 0.0 1e-13 51.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KLO17987.1 - 1e-15 57.7 0.0 2.2e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein PITH PF06201.13 KLO17988.1 - 2.1e-36 125.4 0.3 2.5e-36 125.2 0.3 1.1 1 0 0 1 1 1 1 PITH domain RTC4 PF14474.6 KLO17991.1 - 3.7e-25 88.4 0.0 4.5e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 RTC4-like domain PTS_2-RNA PF01885.16 KLO17992.1 - 3.4e-65 219.5 0.1 4.4e-65 219.1 0.1 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family zf-RING_UBOX PF13445.6 KLO17993.1 - 4.5e-09 36.2 2.3 1.1e-08 34.9 2.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KLO17993.1 - 1.7e-08 34.2 1.5 1.7e-08 34.2 1.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO17993.1 - 3.4e-07 30.0 2.7 9e-07 28.7 2.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO17993.1 - 1.1e-06 28.5 5.2 2.9e-06 27.1 5.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KLO17993.1 - 2.1e-06 27.8 1.7 2.1e-06 27.8 1.7 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KLO17993.1 - 5.5e-06 26.1 9.2 3.8e-05 23.5 9.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO17993.1 - 7.7e-05 23.0 10.8 0.00043 20.6 10.8 2.2 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KLO17993.1 - 8.7e-05 22.3 2.6 8.7e-05 22.3 2.6 2.6 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KLO17993.1 - 0.00079 19.3 0.2 0.0019 18.0 0.2 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KLO17993.1 - 0.0019 18.3 2.5 0.004 17.3 2.5 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 KLO17993.1 - 0.0075 15.9 0.5 0.019 14.6 0.5 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF16 PF01519.16 KLO17993.1 - 0.072 13.6 2.3 0.17 12.4 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Pox_A_type_inc PF04508.12 KLO17993.1 - 0.73 9.8 8.4 0.56 10.1 5.4 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat MPS2 PF17060.5 KLO17993.1 - 0.79 8.9 3.4 1.2 8.3 3.4 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 FAM76 PF16046.5 KLO17993.1 - 1.3 8.3 10.4 2.1 7.7 10.4 1.3 1 0 0 1 1 1 0 FAM76 protein zf-rbx1 PF12678.7 KLO17993.1 - 3.2 8.1 7.4 11 6.4 7.4 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain RINGv PF12906.7 KLO17994.1 - 1.2e-15 57.4 7.2 2e-15 56.6 7.2 1.4 1 0 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 KLO17994.1 - 0.013 15.5 5.2 0.024 14.7 5.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KLO17994.1 - 0.068 13.5 9.1 0.11 12.8 9.1 1.4 1 0 0 1 1 1 0 Ring finger domain CDC45 PF02724.14 KLO17994.1 - 0.18 10.1 0.3 0.27 9.5 0.3 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-RING-like PF08746.11 KLO17994.1 - 3.1 8.2 5.0 5.8 7.3 5.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-rbx1 PF12678.7 KLO17994.1 - 8.2 6.8 7.5 14 6.1 7.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain Arginosuc_synth PF00764.19 KLO17995.1 - 7.8e-158 525.8 0.0 9.4e-158 525.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KLO17995.1 - 0.00013 21.5 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KLO17995.1 - 0.0034 16.2 0.0 0.0053 15.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase GluRS_N PF18466.1 KLO17995.1 - 0.21 12.0 0.2 0.86 10.1 0.2 2.1 1 1 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain PriC PF07445.12 KLO17996.1 - 0.0098 15.8 3.2 0.026 14.5 3.2 1.7 1 0 0 1 1 1 1 Primosomal replication protein priC FAM110_C PF14160.6 KLO17996.1 - 0.045 14.8 1.3 0.38 11.8 0.2 3.2 2 1 0 2 2 2 0 Centrosome-associated C terminus UBA_2 PF08587.11 KLO17996.1 - 0.088 12.9 0.3 0.33 11.1 0.3 2.1 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Pro-kuma_activ PF09286.11 KLO17997.1 - 7.1e-36 123.6 0.0 4e-35 121.2 0.1 2.1 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KLO17997.1 - 1.2e-05 24.8 1.0 2.4e-05 23.8 1.0 1.4 1 0 0 1 1 1 1 Subtilase family zf-TFIIIC PF12660.7 KLO17998.1 - 1.6e-22 79.4 0.1 5.1e-22 77.7 0.1 1.9 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 KLO17998.1 - 1.2e-18 67.7 4.2 1.2e-18 67.7 4.2 2.0 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term ANAPC4_WD40 PF12894.7 KLO17998.1 - 0.0012 19.1 0.1 0.034 14.4 0.1 3.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-ribbon_3 PF13248.6 KLO17998.1 - 2.6 7.6 5.2 38 3.9 0.1 3.0 2 0 0 2 2 2 0 zinc-ribbon domain RNA_pol_3_Rpc31 PF11705.8 KLO17999.1 - 0.00044 20.6 6.1 0.00052 20.3 6.1 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 KLO17999.1 - 0.028 14.1 11.0 0.038 13.7 11.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 KLO17999.1 - 1.7 8.1 13.6 2.4 7.7 13.6 1.1 1 0 0 1 1 1 0 PPP4R2 DUF2457 PF10446.9 KLO17999.1 - 2.2 7.3 18.9 3.2 6.8 18.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.13 KLO17999.1 - 2.8 7.7 9.6 3.9 7.3 9.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 KLO17999.1 - 4.4 5.3 20.4 5.6 4.9 20.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 KLO17999.1 - 6.7 5.1 9.1 6.9 5.1 9.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 KLO17999.1 - 8 4.5 15.4 9.2 4.3 15.4 1.0 1 0 0 1 1 1 0 Nop14-like family ECR1_N PF14382.6 KLO18000.1 - 1.5e-15 56.7 0.2 3.2e-15 55.6 0.2 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KLO18000.1 - 2.4e-13 50.2 0.0 4.8e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-MYND PF01753.18 KLO18001.1 - 1.3e-05 25.2 18.9 1.3e-05 25.2 18.9 2.3 3 0 0 3 3 3 1 MYND finger MRP-L20 PF12824.7 KLO18001.1 - 0.026 14.7 0.9 0.047 13.9 0.9 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 RRM_1 PF00076.22 KLO18002.1 - 1.4e-14 53.6 0.1 3e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KLO18002.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KLO18002.1 - 0.032 14.3 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Chromo_shadow PF01393.19 KLO18003.1 - 1.4e-12 47.5 1.0 3e-11 43.2 0.1 2.5 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 KLO18003.1 - 3.8e-09 36.3 1.3 3.8e-09 36.3 1.3 2.4 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain ABC2_membrane_3 PF12698.7 KLO18003.1 - 0.27 10.3 0.0 0.46 9.5 0.0 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein zf-MYND PF01753.18 KLO18004.1 - 1.3e-08 34.8 13.4 2.2e-08 34.0 13.4 1.4 1 0 0 1 1 1 1 MYND finger NusA_N PF08529.11 KLO18004.1 - 0.15 12.5 0.0 80 3.6 0.0 3.4 3 0 0 3 3 3 0 NusA N-terminal domain zf-HIT PF04438.16 KLO18004.1 - 2.7 8.0 6.8 7 6.6 6.8 1.8 1 0 0 1 1 1 0 HIT zinc finger zf-C2H2 PF00096.26 KLO18005.1 - 0.00013 22.2 1.9 0.00021 21.6 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO18005.1 - 0.00043 20.9 2.2 0.00068 20.3 2.2 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.12 KLO18005.1 - 0.0061 16.8 0.6 0.0084 16.4 0.6 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KLO18005.1 - 0.044 14.1 0.0 0.061 13.6 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KLO18005.1 - 0.064 12.9 0.2 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain OrsD PF12013.8 KLO18005.1 - 0.14 12.6 0.3 0.22 11.9 0.3 1.3 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Iso_dh PF00180.20 KLO18006.1 - 8.9e-79 265.1 0.0 1e-78 265.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.16 KLO18008.1 - 8.8e-40 136.7 49.0 1.3e-38 132.8 48.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily BatA PF07584.11 KLO18008.1 - 0.0069 16.7 0.1 1.9 8.9 0.0 3.5 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal Phage_holin_2_1 PF04971.12 KLO18008.1 - 0.089 12.8 0.4 0.089 12.8 0.4 2.9 2 0 0 2 2 2 0 Bacteriophage P21 holin S DUF3087 PF11286.8 KLO18008.1 - 0.45 10.0 5.1 0.33 10.4 1.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) DUF3377 PF11857.8 KLO18008.1 - 1 9.3 2.7 2.9 7.9 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) MFS_4 PF06779.14 KLO18008.1 - 1.1 8.5 29.6 0.45 9.7 11.1 3.1 1 1 2 3 3 3 0 Uncharacterised MFS-type transporter YbfB DUF680 PF05079.12 KLO18008.1 - 5.4 7.8 6.4 0.78 10.5 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF680) GST_N_3 PF13417.6 KLO18009.1 - 3.7e-07 30.5 0.0 7.7e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO18009.1 - 2e-06 28.0 0.0 3.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KLO18009.1 - 0.0038 17.4 0.0 0.0077 16.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KLO18009.1 - 0.0074 16.3 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KLO18009.1 - 0.0094 16.1 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Piwi PF02171.17 KLO18011.1 - 4.2e-90 302.0 0.0 5.7e-90 301.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KLO18011.1 - 2.2e-27 96.4 0.0 4e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KLO18011.1 - 2e-17 62.6 0.0 6.8e-17 60.9 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoMid PF16487.5 KLO18011.1 - 3.9e-14 52.7 0.0 1.3e-13 51.0 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 KLO18011.1 - 3.4e-11 43.3 0.0 1.5e-10 41.3 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 KLO18011.1 - 5e-11 42.6 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Histidinol_dh PF00815.20 KLO18012.1 - 5.5e-166 552.6 2.3 7.5e-166 552.2 2.3 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KLO18012.1 - 1.9e-23 82.1 0.2 4.2e-23 80.9 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KLO18012.1 - 1.7e-13 50.8 0.2 6.1e-13 49.0 0.2 2.0 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Transket_pyr PF02779.24 KLO18013.1 - 2.4e-47 160.9 0.0 6.7e-47 159.5 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KLO18013.1 - 4.8e-41 139.5 0.1 9.4e-41 138.6 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KLO18013.1 - 0.0089 16.3 0.1 0.023 15.0 0.0 1.7 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II adh_short PF00106.25 KLO18014.1 - 2e-42 144.9 0.0 2.5e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO18014.1 - 1.7e-33 116.1 0.0 2.2e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO18014.1 - 1.7e-12 47.6 0.3 6.4e-12 45.7 0.3 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO18014.1 - 0.0002 20.9 0.1 0.002 17.7 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KLO18014.1 - 0.0026 17.5 0.2 0.0055 16.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 KLO18014.1 - 0.057 12.7 0.1 0.5 9.7 0.1 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 KLO18014.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CDC45 PF02724.14 KLO18016.1 - 0.0033 15.8 3.1 0.0033 15.8 3.1 1.7 2 0 0 2 2 2 1 CDC45-like protein zf-RRN7 PF11781.8 KLO18016.1 - 0.017 14.8 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Apt1 PF10351.9 KLO18016.1 - 0.051 12.4 1.9 0.11 11.3 1.9 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAPS PF04499.15 KLO18016.1 - 0.24 10.2 1.8 0.38 9.5 1.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 KLO18016.1 - 0.35 9.8 1.8 0.77 8.7 1.8 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.7 KLO18016.1 - 2.1 6.4 5.3 3.4 5.7 5.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.12 KLO18016.1 - 4.7 5.3 15.7 0.023 12.9 6.3 1.7 2 0 0 2 2 2 0 Nop14-like family GST_N_3 PF13417.6 KLO18017.1 - 3.9e-11 43.2 0.0 7.7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO18017.1 - 2.5e-08 34.1 0.0 5.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO18017.1 - 0.00021 21.2 0.4 0.0007 19.6 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO18017.1 - 0.003 17.7 0.1 0.0056 16.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KLO18017.1 - 0.005 17.0 0.1 0.01 16.0 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KLO18017.1 - 0.0092 16.3 0.0 0.074 13.4 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KLO18018.1 - 4.2e-11 43.1 0.0 9.7e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO18018.1 - 5.3e-10 39.5 0.0 1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO18018.1 - 4.4e-05 23.4 0.0 9.9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KLO18018.1 - 0.00074 19.8 0.0 0.004 17.5 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO18018.1 - 0.0022 18.2 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO18018.1 - 0.0024 18.0 0.0 0.0039 17.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KLO18018.1 - 0.0073 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Raptor_N PF14538.6 KLO18019.1 - 3.1e-62 208.9 0.1 6.2e-62 207.9 0.1 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 KLO18019.1 - 1.5e-09 37.3 0.9 8.2e-05 22.5 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat WD40 PF00400.32 KLO18019.1 - 4.6e-08 33.6 8.2 0.053 14.4 0.5 6.7 7 0 0 7 7 7 2 WD domain, G-beta repeat HEAT_2 PF13646.6 KLO18019.1 - 0.0031 17.9 0.0 0.031 14.7 0.0 2.7 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 KLO18019.1 - 0.0044 17.5 2.0 0.01 16.3 0.0 2.7 3 0 0 3 3 3 1 HEAT-like repeat ANAPC4_WD40 PF12894.7 KLO18019.1 - 0.021 15.1 0.0 7.4 6.9 0.0 3.7 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 KLO18019.1 - 0.024 14.7 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF4680 PF15730.5 KLO18019.1 - 4.8 7.5 5.3 1.2 9.5 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) HALZ PF02183.18 KLO18020.1 - 0.0061 16.8 0.6 0.0061 16.8 0.6 6.0 7 0 0 7 7 7 2 Homeobox associated leucine zipper AGH PF17558.2 KLO18020.1 - 0.24 11.6 1.5 1.4 9.1 1.5 2.3 1 0 0 1 1 1 0 Androgenic gland hormone ATG16 PF08614.11 KLO18020.1 - 1.6 8.9 105.1 0.24 11.6 4.2 7.6 3 1 3 6 6 6 0 Autophagy protein 16 (ATG16) Spt5_N PF11942.8 KLO18021.1 - 0.0054 17.7 0.1 0.0087 17.0 0.1 1.4 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal FAM199X PF15814.5 KLO18021.1 - 0.18 10.8 2.8 0.24 10.4 2.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X DUF4551 PF15087.6 KLO18021.1 - 0.58 8.9 3.1 0.63 8.8 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CK_II_beta PF01214.18 KLO18022.1 - 5.8e-75 251.1 0.0 7.5e-75 250.7 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit YL1 PF05764.13 KLO18022.1 - 0.00013 22.2 3.6 0.00017 21.8 3.6 1.1 1 0 0 1 1 1 1 YL1 nuclear protein BUD22 PF09073.10 KLO18022.1 - 0.034 13.5 10.7 0.047 13.0 10.7 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 KLO18022.1 - 0.14 11.7 4.3 0.2 11.3 4.3 1.3 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 KLO18022.1 - 0.17 11.3 10.5 0.24 10.8 10.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KLO18022.1 - 0.19 10.0 7.4 0.24 9.6 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KLO18022.1 - 0.23 9.7 10.2 0.29 9.3 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 KLO18022.1 - 0.57 9.1 9.9 0.8 8.6 9.9 1.1 1 0 0 1 1 1 0 Paf1 Ribosomal_L36e PF01158.18 KLO18023.1 - 5.7e-40 135.5 5.2 6.3e-40 135.3 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 4HB_MCP_1 PF12729.7 KLO18023.1 - 0.008 15.7 0.0 0.0096 15.5 0.0 1.1 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction Med30 PF11315.8 KLO18023.1 - 0.076 13.2 0.8 0.11 12.7 0.7 1.3 1 1 0 1 1 1 0 Mediator complex subunit 30 Hydantoinase_A PF01968.18 KLO18024.1 - 1.4e-95 319.9 0.0 2.3e-95 319.2 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KLO18024.1 - 4.9e-58 195.8 0.0 3.1e-55 186.6 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF1673 PF07895.11 KLO18025.1 - 0.38 10.4 2.2 0.54 9.9 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) SNARE_assoc PF09335.11 KLO18026.1 - 9.7e-18 64.8 1.6 9.7e-18 64.8 1.6 2.1 2 1 0 2 2 2 1 SNARE associated Golgi protein Mito_carr PF00153.27 KLO18028.1 - 3.8e-63 209.4 4.3 3.4e-24 84.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KLO18028.1 - 0.00051 20.4 0.0 0.034 14.6 0.0 3.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KLO18028.1 - 0.0011 18.4 0.0 0.039 13.5 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KLO18028.1 - 0.0026 17.6 0.0 0.025 14.5 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KLO18028.1 - 0.015 14.8 0.6 0.084 12.4 0.2 2.3 2 0 0 2 2 2 0 EF hand MFS_1 PF07690.16 KLO18029.1 - 9.9e-38 129.9 27.6 1.3e-37 129.5 27.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HIP1_clath_bdg PF16515.5 KLO18030.1 - 0.041 14.5 5.2 0.15 12.7 5.2 1.9 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ran-binding PF05508.11 KLO18030.1 - 0.096 11.6 2.4 0.12 11.3 2.4 1.1 1 0 0 1 1 1 0 RanGTP-binding protein CENP-H PF05837.12 KLO18030.1 - 0.2 12.1 5.7 0.13 12.7 3.8 1.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 KLO18030.1 - 1 9.4 6.2 0.64 10.1 4.6 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ribosomal_L6e PF01159.19 KLO18031.1 - 8.9e-39 132.5 0.3 1.6e-38 131.6 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e CRCB PF02537.15 KLO18033.1 - 5.5e-32 109.9 19.0 8.4e-19 67.7 7.2 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) RskA PF10099.9 KLO18034.1 - 0.016 15.5 0.5 0.021 15.1 0.5 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TRP PF06011.12 KLO18034.1 - 0.062 12.0 0.0 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel 60KD_IMP PF02096.20 KLO18035.1 - 2.3e-12 47.1 0.0 3.8e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 60Kd inner membrane protein DNA_pol_E_B PF04042.16 KLO18036.1 - 7.8e-39 133.2 0.2 1.2e-38 132.6 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KLO18036.1 - 0.0027 17.8 0.6 0.0097 16.0 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase delta subunit OB-fold domain HAD_2 PF13419.6 KLO18037.1 - 5.5e-11 42.9 0.0 9.8e-11 42.1 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KLO18037.1 - 1.6e-10 41.7 0.0 1.3e-09 38.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 KLO18037.1 - 0.00041 19.9 0.0 0.86 9.0 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF2608) Acid_PPase PF12689.7 KLO18037.1 - 0.00047 20.0 0.0 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 Acid Phosphatase Hydrolase_like PF13242.6 KLO18037.1 - 0.00053 20.0 0.0 0.0014 18.6 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like TOM20_plant PF06552.12 KLO18037.1 - 0.044 13.5 0.0 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 MFS_1 PF07690.16 KLO18038.1 - 6.8e-51 173.2 42.0 4.4e-50 170.6 40.9 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KLO18038.1 - 5.8e-22 77.9 13.7 6.7e-22 77.6 13.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KLO18038.1 - 9.1e-08 31.4 26.7 3.4e-06 26.2 26.7 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3611 PF12263.8 KLO18038.1 - 0.023 14.6 2.0 0.023 14.6 2.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) HAD_2 PF13419.6 KLO18039.1 - 7.8e-10 39.1 0.0 1.4e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KLO18039.1 - 1.3e-08 35.4 0.0 1.4e-07 32.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_S80 PF07230.11 KLO18039.1 - 0.064 11.5 0.0 0.092 11.0 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) DUF2608 PF11019.8 KLO18039.1 - 0.073 12.6 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) UPF0183 PF03676.14 KLO18040.1 - 4.9e-52 177.5 0.0 1e-51 176.5 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) Apt1 PF10351.9 KLO18041.1 - 9.2 5.0 11.1 12 4.6 11.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Apt1 PF10351.9 KLO18042.1 - 4.5e-84 283.0 2.5 8e-84 282.2 2.5 1.4 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KLO18042.1 - 3.6e-55 187.7 0.0 5.9e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KLO18042.1 - 2.2e-36 125.3 0.0 4.5e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KLO18042.1 - 2.5e-27 95.7 0.0 9.7e-27 93.8 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KLO18042.1 - 2.8e-18 66.5 0.0 1.1e-17 64.7 0.0 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.9 KLO18042.1 - 1e-05 23.9 5.7 0.0079 14.3 3.7 3.0 2 1 0 2 2 2 2 Mitochondrial protein from FMP27 DUF5452 PF17533.2 KLO18042.1 - 0.15 12.1 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5452) NAD_binding_10 PF13460.6 KLO18043.1 - 5.8e-09 36.1 0.4 8.4e-09 35.6 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KLO18043.1 - 5e-05 22.9 0.0 6.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KLO18043.1 - 0.00021 21.7 0.2 0.00077 19.9 0.2 2.0 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KLO18043.1 - 0.026 14.8 0.1 0.05 13.9 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KLO18043.1 - 0.057 12.6 0.3 9.1 5.4 0.0 2.2 1 1 0 2 2 2 0 Male sterility protein NAD_binding_10 PF13460.6 KLO18044.1 - 8.6e-07 29.0 0.1 1.2e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KLO18044.1 - 0.025 14.0 0.1 0.036 13.5 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HAD_2 PF13419.6 KLO18045.1 - 5.5e-18 65.7 0.0 9.4e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KLO18045.1 - 2.6e-12 47.5 0.0 1.7e-06 28.5 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO18045.1 - 4.5e-06 26.6 0.0 9.8e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 KLO18045.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Tubulin PF00091.25 KLO18046.1 - 3.1e-66 223.3 0.0 4.1e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KLO18046.1 - 3.9e-48 162.8 0.0 5.9e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KLO18046.1 - 0.00031 20.5 0.0 0.00059 19.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.25 KLO18046.1 - 0.031 14.1 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_3 PF07859.13 KLO18047.1 - 6.2e-39 134.0 0.1 3.2e-30 105.6 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO18047.1 - 8.2e-10 38.1 0.0 2.2e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 KLO18047.1 - 0.032 14.1 0.0 0.099 12.4 0.0 1.8 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DSPc PF00782.20 KLO18048.1 - 1.4e-30 105.8 0.0 1.6e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KLO18048.1 - 0.00071 19.2 0.0 0.00098 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KLO18048.1 - 0.0019 18.5 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Meth_synt_2 PF01717.18 KLO18049.1 - 9.5e-152 504.9 0.0 4.9e-148 492.7 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KLO18049.1 - 1.4e-118 396.0 0.0 5.9e-113 377.5 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain DUF2985 PF11204.8 KLO18050.1 - 1.8e-29 101.7 2.1 4.2e-29 100.5 2.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) OAD_gamma PF04277.13 KLO18050.1 - 2.5 8.7 5.1 6.9 7.3 1.7 2.7 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Sec15 PF04091.12 KLO18051.1 - 7.4e-93 311.4 3.8 1.7e-92 310.2 3.8 1.6 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 KLO18051.1 - 1.3e-06 28.6 1.0 1.3e-06 28.6 1.0 3.9 3 1 0 4 4 4 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 KLO18051.1 - 3.1e-06 27.1 8.6 2.5e-05 24.2 1.0 3.7 4 0 0 4 4 4 2 Sec8 exocyst complex component specific domain Vps51 PF08700.11 KLO18051.1 - 2.7e-05 24.2 0.9 0.0002 21.4 0.2 2.8 1 1 1 2 2 2 1 Vps51/Vps67 MnmE_helical PF12631.7 KLO18051.1 - 0.0065 16.7 15.6 4.7 7.3 2.7 4.2 4 0 0 4 4 4 2 MnmE helical domain Ku_PK_bind PF08785.11 KLO18051.1 - 0.024 14.8 6.8 9.2 6.4 0.0 5.2 4 2 1 5 5 5 0 Ku C terminal domain like JHD PF17811.1 KLO18051.1 - 0.059 13.9 0.4 0.69 10.5 0.0 2.7 2 0 0 2 2 2 0 Jumonji helical domain COG2 PF06148.11 KLO18051.1 - 0.078 13.1 12.3 0.17 12.0 3.1 4.1 4 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 KLO18051.1 - 0.89 10.1 5.5 1.3 9.6 1.2 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PCRF PF03462.18 KLO18051.1 - 0.9 9.4 6.8 4.2 7.2 0.1 3.1 2 1 1 3 3 3 0 PCRF domain DUF1664 PF07889.12 KLO18051.1 - 2.1 8.4 6.1 5.7 7.0 1.6 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Arf PF00025.21 KLO18052.1 - 6.6e-70 234.1 0.0 7.5e-70 233.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KLO18052.1 - 4.2e-14 52.4 0.0 5.3e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KLO18052.1 - 9.7e-14 51.6 0.0 1.4e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KLO18052.1 - 4e-13 49.3 0.0 4.4e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KLO18052.1 - 7.1e-11 41.9 0.6 7.5e-08 31.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KLO18052.1 - 3e-08 33.3 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KLO18052.1 - 2.1e-05 24.6 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KLO18052.1 - 0.029 13.7 0.1 0.042 13.1 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase TPM_phosphatase PF04536.14 KLO18052.1 - 0.12 12.6 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 TPM domain Lactamase_B_6 PF16661.5 KLO18053.1 - 1.2e-46 158.6 0.0 4.5e-46 156.7 0.0 2.0 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KLO18053.1 - 4.2e-26 92.1 12.0 1.1e-25 90.8 0.0 4.5 4 1 0 4 4 4 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KLO18053.1 - 1.6e-18 67.0 0.0 3.6e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KLO18053.1 - 0.00042 20.2 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain PPV_E1_N PF00524.18 KLO18053.1 - 4.3 7.8 8.7 7.9 6.9 7.4 2.1 1 1 1 2 2 2 0 E1 Protein, N terminal domain Arf PF00025.21 KLO18054.1 - 5.1e-78 260.5 0.2 6e-78 260.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KLO18054.1 - 2.9e-14 53.3 0.0 4.1e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KLO18054.1 - 4.3e-13 49.1 0.0 5.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KLO18054.1 - 1.7e-12 47.2 1.7 1.9e-08 33.8 0.2 2.6 1 1 2 3 3 3 2 G-protein alpha subunit Ras PF00071.22 KLO18054.1 - 1.8e-12 47.2 0.0 1.9e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KLO18054.1 - 4.8e-11 42.5 0.0 5.9e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KLO18054.1 - 4.4e-06 26.7 0.0 7.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KLO18054.1 - 0.0069 15.7 0.2 0.029 13.7 0.1 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase tRNA-synt_1c PF00749.21 KLO18055.1 - 1.1e-96 323.4 0.0 3.5e-96 321.8 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 KLO18055.1 - 1.9e-41 141.7 0.1 3.3e-41 141.0 0.1 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 KLO18055.1 - 5.9e-28 97.9 0.0 1.3e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KLO18055.1 - 6.8e-06 26.9 1.2 3.3e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Glyco_hydro_79C PF16862.5 KLO18056.1 - 6.4e-10 39.9 0.0 2e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain AAA PF00004.29 KLO18057.1 - 1.7e-20 73.7 0.0 3e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KLO18057.1 - 0.13 12.6 0.0 1.9 8.8 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KLO18057.1 - 0.27 11.5 0.4 4 7.7 0.0 2.4 1 1 0 2 2 2 0 AAA domain MAS20 PF02064.15 KLO18058.1 - 1.7e-31 109.0 0.3 5.2e-31 107.4 0.3 1.8 1 0 0 1 1 1 1 MAS20 protein import receptor SET PF00856.28 KLO18058.1 - 8.2e-12 45.8 0.0 4.5e-11 43.4 0.0 2.3 1 1 1 2 2 2 2 SET domain zf-MYND PF01753.18 KLO18058.1 - 0.00031 20.8 0.6 0.00031 20.8 0.6 1.7 2 0 0 2 2 2 1 MYND finger COX14 PF14880.6 KLO18058.1 - 0.0028 17.5 0.0 0.0069 16.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Nucleolin_bd PF16725.5 KLO18058.1 - 0.18 11.5 4.8 0.71 9.6 2.1 2.7 2 0 0 2 2 2 0 Nucleolin binding domain GST_N_3 PF13417.6 KLO18059.1 - 1.1e-08 35.3 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO18059.1 - 0.0016 18.6 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO18059.1 - 0.066 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KLO18059.1 - 0.1 12.9 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glyco_hydro_125 PF06824.11 KLO18061.1 - 8.1e-151 502.6 0.0 9.3e-151 502.4 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) SeleniumBinding PF11524.8 KLO18061.1 - 0.1 13.1 0.1 0.34 11.4 0.0 1.9 2 0 0 2 2 2 0 Selenium binding protein Exo_endo_phos PF03372.23 KLO18062.1 - 4.2e-08 33.0 0.1 5.9e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Zn_ribbon_17 PF17120.5 KLO18063.1 - 1.9e-08 33.8 8.1 2e-08 33.7 1.3 2.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KLO18063.1 - 6.2e-05 23.7 12.7 0.012 16.4 1.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat Zf_RING PF16744.5 KLO18063.1 - 0.023 14.8 1.3 0.023 14.8 1.3 1.9 1 1 1 2 2 2 0 KIAA1045 RING finger PHD_4 PF16866.5 KLO18063.1 - 3.9 7.7 6.3 0.81 9.8 2.2 2.0 2 0 0 2 2 2 0 PHD-finger Acetyltransf_10 PF13673.7 KLO18064.1 - 1.8e-08 34.4 0.0 2.6e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO18064.1 - 2.9e-08 34.0 0.0 4.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO18064.1 - 4.3e-07 30.2 0.0 5.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KLO18064.1 - 4.5e-06 26.7 0.0 6.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO18064.1 - 7.4e-05 22.6 0.0 0.00024 21.0 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein AMP-binding_C PF13193.6 KLO18064.1 - 0.042 14.8 0.0 4.1 8.4 0.0 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain SIP1 PF04938.12 KLO18065.1 - 3.6e-32 111.8 0.2 4.9e-32 111.4 0.2 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) TetR_C_23 PF17931.1 KLO18065.1 - 0.04 14.1 0.1 0.53 10.4 0.1 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3245 PF11595.8 KLO18066.1 - 7.2e-09 36.3 10.2 7.2e-09 36.3 10.2 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF3245) EAP30 PF04157.16 KLO18068.1 - 4.6e-65 219.2 0.0 5.3e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DBD_Tnp_Mut PF03108.15 KLO18068.1 - 0.17 11.9 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 MuDR family transposase BRF1 PF07741.13 KLO18069.1 - 0.078 13.3 0.0 0.09 13.1 0.0 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain MBF2 PF15868.5 KLO18070.1 - 0.17 12.5 0.0 0.43 11.1 0.0 1.7 1 0 0 1 1 1 0 Transcription activator MBF2 Pkinase PF00069.25 KLO18071.1 - 9.4e-71 238.3 0.0 2e-70 237.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO18071.1 - 7.1e-32 110.7 0.0 2e-30 105.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO18071.1 - 0.00017 21.0 2.3 0.4 10.0 0.4 3.7 3 1 0 3 3 3 2 Kinase-like RIO1 PF01163.22 KLO18071.1 - 0.00097 18.8 0.3 0.00097 18.8 0.3 1.6 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 KLO18071.1 - 0.01 14.6 0.2 0.021 13.6 0.0 1.8 2 1 0 2 2 2 0 Fungal protein kinase Mg_trans_NIPA PF05653.14 KLO18072.1 - 2e-58 197.9 10.6 1.2e-53 182.1 7.1 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KLO18072.1 - 0.00022 21.4 1.7 0.00022 21.4 1.7 3.5 3 1 1 4 4 4 1 EamA-like transporter family VMA21 PF09446.10 KLO18072.1 - 0.045 13.9 0.8 0.16 12.1 0.8 2.0 1 0 0 1 1 1 0 VMA21-like domain WD40 PF00400.32 KLO18073.1 - 2.9e-12 46.9 0.3 0.00044 21.0 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO18073.1 - 4.8e-06 26.8 0.0 0.0045 17.3 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 KLO18073.1 - 0.0046 17.2 0.2 0.35 11.2 0.0 3.4 3 1 1 4 4 4 1 Kelch motif TFIID-31kDa PF02291.15 KLO18074.1 - 3.1e-32 111.2 0.0 3.4e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KLO18074.1 - 1.2e-05 25.4 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KLO18074.1 - 8.4e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 KLO18074.1 - 0.00024 21.4 0.0 0.00032 21.0 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein FMN_red PF03358.15 KLO18074.1 - 0.028 14.1 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Histone PF00125.24 KLO18074.1 - 0.031 14.7 0.0 0.038 14.4 0.0 1.1 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF2415 PF10313.9 KLO18074.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Actin PF00022.19 KLO18076.1 - 6.2e-24 84.3 0.0 8.6e-10 37.8 0.1 3.4 3 0 0 3 3 3 3 Actin Actin_micro PF17003.5 KLO18076.1 - 2.8e-14 53.1 0.0 4.9e-07 29.3 0.1 2.2 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 KLO18076.1 - 0.00047 19.1 0.0 0.0028 16.5 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein LSM PF01423.22 KLO18077.1 - 1.6e-19 69.4 0.0 1.8e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KLO18077.1 - 0.12 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain MDM10 PF12519.8 KLO18079.1 - 2.4e-92 310.3 0.2 4e-81 273.3 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Pkr1 PF08636.10 KLO18080.1 - 2e-16 59.9 7.7 2.6e-16 59.5 7.7 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FUSC PF04632.12 KLO18080.1 - 0.048 12.2 0.9 0.064 11.8 0.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Gemini_mov PF01708.16 KLO18080.1 - 0.19 11.5 2.5 0.13 12.0 1.2 1.5 1 1 1 2 2 2 0 Geminivirus putative movement protein Sld5 PF05916.11 KLO18081.1 - 4.2e-06 27.2 0.0 5.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Tau95 PF09734.9 KLO18083.1 - 2.9e-40 138.3 0.3 6.5e-40 137.2 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KLO18083.1 - 5.8e-26 91.2 0.0 6.7e-25 87.7 0.0 2.4 2 0 0 2 2 2 1 Tau95 Triple barrel domain Ribosomal_L29e PF01779.17 KLO18084.1 - 1.7e-20 73.0 12.6 2.3e-20 72.6 12.6 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Aconitase PF00330.20 KLO18085.1 - 2.1e-161 538.0 0.0 2.6e-161 537.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KLO18085.1 - 1.9e-36 125.3 0.0 3.2e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain ORC6 PF05460.13 KLO18086.1 - 0.29 10.3 6.1 0.46 9.7 6.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) GTP_EFTU PF00009.27 KLO18087.1 - 5.8e-52 176.1 0.0 1e-51 175.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KLO18087.1 - 4.4e-13 49.1 0.0 2.6e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus EFG_II PF14492.6 KLO18087.1 - 5.6e-12 45.6 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KLO18087.1 - 4.8e-07 30.1 0.0 9.5e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KLO18087.1 - 0.00011 22.3 0.0 0.00028 20.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KLO18087.1 - 0.16 11.4 0.0 0.38 10.2 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ICMT PF04140.14 KLO18088.1 - 8e-27 93.5 1.1 1.6e-26 92.6 1.1 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KLO18088.1 - 9.3e-12 45.3 0.6 9.3e-12 45.3 0.6 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase Suc_Fer-like PF06999.12 KLO18089.1 - 2.8e-24 86.1 0.0 3.3e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like OMPdecase PF00215.24 KLO18091.1 - 2.9e-71 239.6 0.0 3.7e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TruD PF01142.18 KLO18092.1 - 1.1e-76 258.3 0.0 2e-73 247.6 0.0 2.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) MFS_1 PF07690.16 KLO18093.1 - 2.2e-31 109.1 22.3 2e-29 102.6 16.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KLO18093.1 - 0.0089 15.0 0.1 0.021 13.8 0.1 1.7 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM DUF3918 PF13056.6 KLO18093.1 - 0.042 13.5 0.9 0.077 12.6 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Gly_transf_sug PF04488.15 KLO18094.1 - 8.7e-22 77.6 0.2 1.6e-21 76.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KLO18094.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 KLO18094.1 - 0.16 11.2 0.7 0.56 9.4 0.3 1.8 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain PIN_4 PF13638.6 KLO18095.1 - 6.6e-23 81.4 0.0 1.4e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 PIN domain PIN_12 PF16289.5 KLO18095.1 - 0.0041 17.6 0.0 0.012 16.1 0.0 1.9 1 1 0 1 1 1 1 PIN domain DOG1 PF14144.6 KLO18095.1 - 0.027 14.7 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Seed dormancy control GST_N_3 PF13417.6 KLO18097.1 - 3.4e-12 46.6 0.0 6e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO18097.1 - 4e-10 39.8 0.0 7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KLO18097.1 - 0.00027 21.2 0.0 0.00086 19.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KLO18097.1 - 0.00031 20.7 0.0 0.00089 19.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO18097.1 - 0.005 17.0 0.0 0.03 14.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KLO18097.1 - 0.046 14.0 0.0 0.087 13.1 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KLO18097.1 - 0.053 14.3 0.0 0.13 13.0 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain MBD PF01429.19 KLO18097.1 - 0.054 13.2 0.0 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Methyl-CpG binding domain GST_C PF00043.25 KLO18097.1 - 0.085 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 KLO18099.1 - 3.4e-43 147.9 32.0 4.4e-40 137.7 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KLO18099.1 - 0.63 10.3 2.9 1.1 9.5 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) DUF962 PF06127.11 KLO18099.1 - 0.93 9.6 7.2 1.1 9.3 2.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF962) RRM_1 PF00076.22 KLO18100.1 - 1.9e-19 69.2 0.5 1.4e-08 34.5 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KLO18100.1 - 0.0017 17.9 0.0 0.0056 16.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BSP_II PF05432.11 KLO18100.1 - 0.0024 17.6 1.0 0.0032 17.2 1.0 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) RRM_occluded PF16842.5 KLO18100.1 - 0.016 15.0 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif Tim54 PF11711.8 KLO18100.1 - 0.033 13.0 0.3 0.047 12.5 0.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RRN3 PF05327.11 KLO18100.1 - 0.14 10.7 0.3 0.14 10.7 0.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SET_assoc PF11767.8 KLO18100.1 - 0.17 11.5 0.0 0.71 9.6 0.0 1.9 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated DNA_pol_phi PF04931.13 KLO18100.1 - 2.2 6.3 5.6 3 5.8 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAM_LAG1_CLN8 PF03798.16 KLO18101.1 - 1.9e-46 158.3 21.5 1.9e-46 158.3 21.5 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KLO18101.1 - 1.3e-06 27.9 0.1 4.2e-06 26.3 0.1 1.9 1 0 0 1 1 1 1 TRAM1-like protein DSPc PF00782.20 KLO18102.1 - 1.3e-35 122.2 0.4 1.5e-20 73.4 0.4 3.4 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain DSPn PF14671.6 KLO18102.1 - 1.1e-05 25.9 1.0 0.05 14.1 0.0 2.4 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half Y_phosphatase PF00102.27 KLO18102.1 - 3.2e-05 23.6 0.3 0.0016 18.1 0.2 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KLO18102.1 - 0.031 14.0 0.6 0.4 10.3 0.1 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) HsbA PF12296.8 KLO18103.1 - 0.00078 19.9 6.1 0.019 15.4 2.1 2.8 2 0 0 2 2 2 2 Hydrophobic surface binding protein A HCMV_UL139 PF12507.8 KLO18103.1 - 0.031 14.7 1.4 0.031 14.7 1.4 3.4 3 1 1 4 4 4 0 Human Cytomegalovirus UL139 protein CorA PF01544.18 KLO18103.1 - 1.4 8.2 11.7 0.27 10.5 6.7 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF4407 PF14362.6 KLO18103.1 - 1.5 8.1 49.3 1.2 8.5 8.2 4.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) RFX_DNA_binding PF02257.15 KLO18104.1 - 7.2e-28 97.0 0.1 1.3e-27 96.2 0.1 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain Metallophos PF00149.28 KLO18105.1 - 4.2e-08 33.9 1.0 7.4e-08 33.1 1.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-ribbon_3 PF13248.6 KLO18107.1 - 0.039 13.4 1.4 0.13 11.7 1.4 2.0 1 0 0 1 1 1 0 zinc-ribbon domain Retrotrans_gag PF03732.17 KLO18112.1 - 0.023 15.0 0.0 0.058 13.7 0.0 1.7 1 1 0 1 1 1 0 Retrotransposon gag protein zf-C4 PF00105.18 KLO18113.1 - 3.3 8.2 7.1 0.57 10.7 1.7 2.1 2 0 0 2 2 2 0 Zinc finger, C4 type (two domains) CotH PF08757.11 KLO18118.1 - 0.0019 17.8 0.8 0.0019 17.8 0.8 1.4 2 0 0 2 2 2 1 CotH kinase protein DDE_1 PF03184.19 KLO18119.1 - 9e-19 67.8 0.0 1.3e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3656 PF12392.8 KLO18119.1 - 0.068 13.8 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Collagenase Jnk-SapK_ap_N PF09744.9 KLO18120.1 - 1.3 9.2 6.1 1.6 9.0 0.1 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 F-box-like PF12937.7 KLO18122.1 - 0.0072 16.2 0.1 0.019 14.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like CENP-H PF05837.12 KLO18126.1 - 0.067 13.6 3.7 1.7 9.1 0.1 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) UFD1 PF03152.14 KLO18126.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Glutaredoxin2_C PF04399.13 KLO18126.1 - 0.08 12.8 0.7 0.36 10.7 0.7 2.0 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain Lebercilin PF15619.6 KLO18126.1 - 0.15 11.7 7.0 0.25 11.0 7.0 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease F-box-like PF12937.7 KLO18127.1 - 0.06 13.3 0.2 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 KLO18128.1 - 0.0078 16.1 0.1 0.025 14.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO18131.1 - 2.4e-05 24.1 0.2 2.4e-05 24.1 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO18131.1 - 0.58 10.1 3.6 14 5.7 1.8 3.6 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO18132.1 - 1.6e-08 34.3 3.7 9.9e-07 28.6 0.7 2.7 2 0 0 2 2 2 2 F-box-like F-box-like PF12937.7 KLO18133.1 - 2.3e-07 30.6 1.0 2.3e-07 30.6 1.0 2.1 2 0 0 2 2 2 1 F-box-like zf-MYND PF01753.18 KLO18134.1 - 1.2e-08 34.9 10.0 1.2e-08 34.9 10.0 2.0 2 0 0 2 2 2 1 MYND finger Rhodanese_C PF12368.8 KLO18134.1 - 0.02 15.3 4.8 0.066 13.6 4.8 1.9 1 0 0 1 1 1 0 Rhodanase C-terminal F-box-like PF12937.7 KLO18136.1 - 1.8e-05 24.5 1.4 1.8e-05 24.5 1.4 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO18136.1 - 0.05 13.5 1.3 0.8 9.7 1.3 3.0 1 1 0 1 1 1 0 F-box domain DUF3557 PF12078.8 KLO18136.1 - 0.16 11.9 0.1 0.39 10.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) FTH PF01827.27 KLO18136.1 - 0.19 11.5 0.4 1 9.2 0.1 2.0 2 0 0 2 2 2 0 FTH domain F-box-like PF12937.7 KLO18137.1 - 2.7e-10 40.0 1.8 9e-10 38.3 1.8 2.0 1 0 0 1 1 1 1 F-box-like Plavaka PF18759.1 KLO18138.1 - 7.9e-30 104.2 0.0 1.4e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Pkinase PF00069.25 KLO18140.1 - 2.6e-39 135.2 0.0 1e-38 133.3 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO18140.1 - 3.1e-22 79.1 0.0 2.5e-21 76.1 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KLO18140.1 - 0.00014 21.3 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO18140.1 - 0.068 13.1 0.0 8.7 6.2 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO18140.1 - 0.094 12.0 0.0 0.78 9.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Prenyltrans PF00432.21 KLO18141.1 - 1.6e-31 107.7 12.1 1.7e-06 27.7 0.3 6.1 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KLO18141.1 - 0.0065 15.6 0.0 0.71 8.9 0.0 2.3 2 0 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain Nup84_Nup100 PF04121.13 KLO18142.1 - 2.7e-160 534.9 1.8 3.2e-160 534.7 1.8 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Pkinase PF00069.25 KLO18143.1 - 6.7e-27 94.5 0.0 1e-26 93.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO18143.1 - 5.6e-15 55.3 0.0 8.7e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO18143.1 - 0.00016 20.6 0.0 0.00028 19.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KLO18143.1 - 0.0036 17.3 0.2 0.0072 16.3 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3557 PF12078.8 KLO18145.1 - 0.046 13.7 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) F-box-like PF12937.7 KLO18147.1 - 0.0025 17.7 0.0 0.0087 15.9 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO18147.1 - 6.6 6.7 7.2 5.4 7.0 0.3 3.2 2 1 0 2 2 2 0 F-box domain zf-MYND PF01753.18 KLO18148.1 - 2.1e-09 37.3 14.5 3.4e-09 36.6 14.5 1.4 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 KLO18148.1 - 0.095 13.1 6.7 0.21 12.0 6.7 1.6 1 0 0 1 1 1 0 Rhodanase C-terminal PolC_DP2 PF03833.13 KLO18148.1 - 0.47 8.3 5.1 0.7 7.7 4.2 1.6 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.12 KLO18149.1 - 0.027 14.4 1.7 0.12 12.4 0.5 2.1 2 0 0 2 2 2 0 zinc-ribbons zf-P11 PF03854.14 KLO18149.1 - 0.1 12.2 0.5 0.1 12.2 0.5 2.0 2 0 0 2 2 2 0 P-11 zinc finger Actino_peptide PF14408.6 KLO18149.1 - 0.15 12.2 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes zf-ribbon_3 PF13248.6 KLO18149.1 - 2.2 7.8 6.0 31 4.1 6.1 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Phage_int_SAM_2 PF12834.7 KLO18150.1 - 0.13 13.0 0.1 0.21 12.3 0.1 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal TBCC_N PF16752.5 KLO18151.1 - 0.0055 17.1 1.1 0.017 15.5 0.5 2.0 1 1 1 2 2 2 1 Tubulin-specific chaperone C N-terminal domain ABC_tran_CTD PF16326.5 KLO18151.1 - 0.017 15.4 0.3 0.043 14.1 0.3 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain RNase_E_G PF10150.9 KLO18151.1 - 0.039 13.4 0.7 0.056 12.9 0.7 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family MerR-DNA-bind PF09278.11 KLO18151.1 - 0.061 13.9 1.5 2.1 8.9 0.5 2.5 2 0 0 2 2 2 0 MerR, DNA binding RdRP_3 PF00998.23 KLO18151.1 - 0.078 11.7 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase IKBKB_SDD PF18397.1 KLO18151.1 - 0.1 11.9 0.2 0.14 11.4 0.2 1.1 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain zf-RanBP PF00641.18 KLO18151.1 - 0.23 10.8 0.9 0.64 9.4 0.1 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Baculo_PEP_C PF04513.12 KLO18151.1 - 0.24 11.4 4.1 0.65 10.0 3.8 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Hsk3 PF08227.11 KLO18151.1 - 0.27 11.6 1.8 0.77 10.2 0.4 2.2 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DASH_Dad3 PF08656.10 KLO18151.1 - 0.83 9.8 3.5 8.7 6.5 2.6 2.6 1 1 0 1 1 1 0 DASH complex subunit Dad3 F-box-like PF12937.7 KLO18152.1 - 2.8e-08 33.5 0.3 5.7e-08 32.5 0.3 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO18152.1 - 0.083 13.4 0.4 12 6.4 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO18153.1 - 2.2e-05 24.2 0.3 2.2e-05 24.2 0.3 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO18153.1 - 0.0086 15.9 7.5 8.3 6.4 0.0 5.2 4 2 1 5 5 5 3 F-box domain zf-MYND PF01753.18 KLO18154.1 - 1.2e-08 34.9 13.8 2.6e-08 33.8 13.8 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO18154.1 - 1.9 8.7 7.5 4.5 7.4 7.5 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 F-box-like PF12937.7 KLO18155.1 - 0.00082 19.2 0.3 0.0044 16.9 0.3 2.4 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO18155.1 - 0.025 15.0 6.3 16 6.1 0.1 4.2 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Rod-binding PF10135.9 KLO18156.1 - 0.14 12.7 0.2 0.25 12.0 0.2 1.4 1 0 0 1 1 1 0 Rod binding protein SNase PF00565.17 KLO18158.1 - 1.1e-16 61.2 0.0 1.5e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue PHD PF00628.29 KLO18160.1 - 0.0028 17.5 11.9 0.0063 16.4 11.9 1.6 1 0 0 1 1 1 1 PHD-finger DUF1077 PF06417.12 KLO18161.1 - 8.2e-47 158.1 0.4 9.8e-47 157.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) F-box-like PF12937.7 KLO18162.1 - 7.7e-06 25.7 2.4 8e-06 25.7 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO18163.1 - 3.1e-08 33.4 0.4 9.3e-08 31.9 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO18163.1 - 0.17 11.8 0.7 1.9 8.4 0.7 2.8 1 1 0 1 1 1 0 F-box domain Mu-like_Com PF10122.9 KLO18164.1 - 0.016 14.6 1.0 1.1 8.7 0.0 3.0 3 0 0 3 3 3 0 Mu-like prophage protein Com F-box-like PF12937.7 KLO18164.1 - 0.031 14.2 0.1 0.1 12.5 0.1 2.0 1 1 0 1 1 1 0 F-box-like F-box-like PF12937.7 KLO18166.1 - 0.06 13.2 0.4 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 KLO18167.1 - 0.038 13.9 0.2 2.2 8.2 0.0 2.7 2 0 0 2 2 2 0 F-box-like CBM_21 PF03370.13 KLO18168.1 - 9.6e-28 96.6 0.0 1.7e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KLO18168.1 - 3.4e-08 33.9 0.0 8.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) zf-MYND PF01753.18 KLO18170.1 - 6.3e-10 39.0 10.6 1.3e-09 37.9 10.6 1.6 1 0 0 1 1 1 1 MYND finger Zn_ribbon_SprT PF17283.2 KLO18170.1 - 0.72 9.8 12.2 0.12 12.3 7.8 1.9 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF5447 PF17525.2 KLO18170.1 - 2.2 8.8 7.0 4.5 7.8 5.0 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5447) zf-MYND PF01753.18 KLO18171.1 - 3.3e-10 39.9 11.3 7.9e-10 38.7 11.3 1.7 1 0 0 1 1 1 1 MYND finger DUF3119 PF11317.8 KLO18171.1 - 0.0064 16.8 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) Peptidase_C28 PF05408.11 KLO18171.1 - 0.028 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase TAF6_C PF07571.13 KLO18171.1 - 0.074 13.4 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain zf-C6H2 PF15801.5 KLO18171.1 - 0.3 11.4 4.1 1 9.7 4.1 1.9 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KLO18171.1 - 0.66 10.1 2.5 1.8 8.7 2.5 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO18172.1 - 1e-06 28.7 19.6 2.2e-06 27.7 19.6 1.6 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 KLO18172.1 - 0.16 13.1 1.9 0.31 12.2 1.9 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KLO18173.1 - 3.9e-11 42.8 11.3 8e-11 41.8 11.3 1.6 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 KLO18173.1 - 0.08 14.1 0.3 0.17 13.0 0.3 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Rhodanese_C PF12368.8 KLO18173.1 - 0.32 11.4 4.7 1.2 9.6 4.7 1.9 1 0 0 1 1 1 0 Rhodanase C-terminal zf-C6H2 PF15801.5 KLO18173.1 - 0.41 11.0 5.2 0.59 10.5 3.0 2.3 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KLO18173.1 - 1.4 9.1 4.4 4.8 7.4 4.4 2.0 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO18174.1 - 8.2e-08 32.2 11.1 8.2e-08 32.2 11.1 2.9 3 0 0 3 3 3 2 MYND finger TMEM125 PF15109.6 KLO18174.1 - 0.033 14.5 0.0 0.13 12.6 0.0 2.0 1 0 0 1 1 1 0 TMEM125 protein family zf-MYND PF01753.18 KLO18175.1 - 5.2e-09 36.1 14.8 1.2e-08 34.8 14.8 1.7 1 0 0 1 1 1 1 MYND finger UQ_con PF00179.26 KLO18176.1 - 3.3e-08 33.3 0.0 7.4e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 KLO18177.1 - 2.7e-39 135.1 0.0 4.6e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO18177.1 - 6.1e-37 127.3 0.0 9.1e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO18177.1 - 0.00034 20.0 0.0 0.00065 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KLO18177.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO18177.1 - 0.027 14.1 0.1 0.26 10.9 0.0 2.3 3 0 0 3 3 3 0 RIO1 family APH PF01636.23 KLO18177.1 - 0.041 13.8 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-MYND PF01753.18 KLO18178.1 - 1.8e-08 34.3 15.9 1.8e-08 34.3 15.9 1.9 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KLO18178.1 - 7.1 7.0 12.3 16 5.9 12.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KLO18179.1 - 4.4e-10 39.5 9.5 4.4e-10 39.5 9.5 1.9 2 0 0 2 2 2 1 MYND finger Rhodanese_C PF12368.8 KLO18179.1 - 0.085 13.2 5.6 0.24 11.8 5.6 1.7 1 0 0 1 1 1 0 Rhodanase C-terminal zf-MYND PF01753.18 KLO18180.1 - 1.8e-08 34.3 14.9 3.2e-08 33.5 14.9 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KLO18180.1 - 1.3 9.2 6.7 3 8.0 6.7 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KLO18181.1 - 7.9e-08 32.3 11.3 1.4e-07 31.5 11.3 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KLO18181.1 - 0.41 10.5 3.4 0.75 9.7 3.4 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-Mss51 PF13824.6 KLO18181.1 - 1.9 8.6 6.6 3.9 7.6 6.6 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ADH_N PF08240.12 KLO18182.1 - 6.9e-25 87.0 4.1 1.3e-24 86.1 4.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO18182.1 - 1.5e-13 50.8 0.0 2.6e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KLO18182.1 - 2.5e-05 23.7 0.1 4.2e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KLO18182.1 - 0.00014 21.3 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F-box-like PF12937.7 KLO18185.1 - 3.6e-05 23.6 4.1 0.00011 22.0 0.1 3.5 3 1 1 4 4 4 1 F-box-like LRR_4 PF12799.7 KLO18185.1 - 0.1 13.1 6.1 2.7 8.6 0.0 4.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO18186.1 - 4.5e-14 52.1 0.2 9.8e-05 22.2 0.0 4.2 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 KLO18186.1 - 1.1 9.2 7.1 9.5 6.2 0.0 4.5 6 0 0 6 6 6 0 F-box domain F-box-like PF12937.7 KLO18187.1 - 0.00016 21.5 0.0 0.00053 19.8 0.0 2.0 1 0 0 1 1 1 1 F-box-like DUF587 PF04532.12 KLO18187.1 - 0.02 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF587) F-box-like PF12937.7 KLO18188.1 - 1.3e-06 28.2 0.0 3.7e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like Fanconi_A_N PF15865.5 KLO18188.1 - 0.03 13.7 0.2 0.047 13.1 0.2 1.2 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus F-box-like PF12937.7 KLO18189.1 - 2.5e-05 24.1 0.1 7.7e-05 22.5 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO18190.1 - 2.3e-06 27.4 0.1 8.4e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO18192.1 - 1.5e-06 28.0 1.8 2.5e-06 27.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO18194.1 - 2.4e-07 30.5 0.8 5.5e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO18195.1 - 5.2e-06 26.3 0.6 1.1e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO18196.1 - 1.8e-07 31.0 0.2 1e-05 25.3 0.0 2.9 2 0 0 2 2 2 1 F-box-like DFF-C PF09033.10 KLO18196.1 - 0.042 13.8 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain F-box-like PF12937.7 KLO18197.1 - 2.6e-06 27.2 0.5 2.6e-06 27.2 0.5 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO18197.1 - 0.1 12.5 1.0 0.73 9.8 0.2 2.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO18199.1 - 1.8e-07 30.9 0.1 5.7e-07 29.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KLO18199.1 - 0.034 14.6 5.4 6.7 7.3 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO18200.1 - 2.4e-06 27.4 0.1 6.4e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like BORCS8 PF10167.9 KLO18200.1 - 0.18 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 F-box-like PF12937.7 KLO18201.1 - 9.5e-08 31.8 0.1 2.8e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO18202.1 - 0.00053 19.8 1.1 0.0015 18.4 0.4 2.2 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.25 KLO18203.1 - 1.4e-57 195.1 0.0 7.1e-31 107.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO18203.1 - 9e-56 189.0 0.0 5.5e-27 94.7 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KLO18203.1 - 1.8e-05 24.2 0.0 0.14 11.5 0.0 2.5 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KLO18203.1 - 4.2e-05 23.2 0.1 0.054 13.1 0.0 2.4 2 0 0 2 2 2 2 RIO1 family Pkinase_fungal PF17667.1 KLO18203.1 - 0.00057 18.8 0.0 0.31 9.8 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 KLO18203.1 - 0.0055 16.7 0.0 0.48 10.3 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Lentiviral_Tat PF02998.14 KLO18203.1 - 0.091 12.8 0.6 13 5.9 0.0 2.6 2 0 0 2 2 2 0 Lentiviral Tat protein ABC1 PF03109.16 KLO18203.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Pyr_redox_3 PF13738.6 KLO18204.1 - 3.5e-21 75.8 0.0 7.7e-18 64.8 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KLO18204.1 - 8e-20 70.7 0.0 1.9e-18 66.2 0.1 2.6 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KLO18204.1 - 1.9e-15 56.9 0.0 7.9e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KLO18204.1 - 1e-11 44.6 0.0 1e-07 31.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KLO18204.1 - 1.5e-07 31.9 0.8 0.022 15.3 0.3 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KLO18204.1 - 0.00044 19.6 0.1 0.016 14.5 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KLO18204.1 - 0.0011 18.4 0.1 0.045 13.1 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KLO18204.1 - 0.0025 18.0 0.0 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KLO18204.1 - 0.0076 15.3 0.8 1 8.4 0.1 3.4 4 0 0 4 4 4 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KLO18204.1 - 0.015 14.4 0.3 0.058 12.5 0.6 1.8 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 KLO18204.1 - 0.017 15.0 0.2 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KLO18204.1 - 0.022 13.5 0.1 0.042 12.6 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KLO18204.1 - 0.034 13.2 0.6 0.1 11.6 0.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KLO18204.1 - 0.041 13.1 0.1 0.4 9.9 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 KLO18204.1 - 0.042 13.9 0.1 4 7.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SnoaL_2 PF12680.7 KLO18204.1 - 0.065 13.9 0.0 0.22 12.2 0.0 1.9 1 0 0 1 1 1 0 SnoaL-like domain DAO PF01266.24 KLO18204.1 - 0.076 12.6 1.0 2.3 7.7 0.4 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase NTF2 PF02136.20 KLO18204.1 - 0.12 13.0 0.0 0.47 11.0 0.0 2.0 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain TrkA_N PF02254.18 KLO18204.1 - 0.19 12.0 0.7 0.51 10.6 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain FMO-like PF00743.19 KLO18206.1 - 7.1e-17 61.0 0.0 2.6e-16 59.2 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KLO18206.1 - 3.4e-14 52.8 0.0 5.4e-10 39.0 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KLO18206.1 - 1e-08 34.8 0.0 3.9e-05 23.0 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KLO18206.1 - 9.9e-05 21.6 0.0 0.49 9.5 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KLO18206.1 - 0.0002 21.8 0.1 0.017 15.6 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KLO18206.1 - 0.0014 17.8 0.1 0.97 8.4 0.1 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KLO18206.1 - 0.0024 17.2 0.0 0.0081 15.5 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KLO18206.1 - 0.0069 16.6 0.0 0.033 14.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO18206.1 - 0.017 14.7 0.1 0.83 9.2 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KLO18206.1 - 0.02 14.0 0.5 0.16 11.1 0.3 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KLO18206.1 - 0.035 12.8 0.1 0.066 11.9 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 KLO18206.1 - 0.044 13.1 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KLO18206.1 - 0.046 12.8 0.1 0.13 11.3 0.4 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KLO18206.1 - 0.11 12.5 0.2 12 5.9 0.2 3.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding SnoaL_2 PF12680.7 KLO18206.1 - 0.13 12.9 0.1 0.41 11.3 0.1 1.9 1 0 0 1 1 1 0 SnoaL-like domain F-box-like PF12937.7 KLO18207.1 - 2.2e-05 24.3 0.0 6.2e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO18208.1 - 0.00011 22.0 0.4 0.00049 19.9 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO18213.1 - 2.4e-07 30.5 1.9 1.9e-06 27.6 0.5 2.9 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KLO18213.1 - 0.13 12.2 0.7 21 5.1 0.1 3.0 2 0 0 2 2 2 0 F-box domain p450 PF00067.22 KLO18216.1 - 5.6e-61 206.7 0.0 7.6e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sarcoglycan_1 PF04790.13 KLO18217.1 - 0.38 10.1 0.1 0.38 10.1 0.1 1.9 2 0 0 2 2 2 0 Sarcoglycan complex subunit protein CoA_binding_3 PF13727.6 KLO18217.1 - 1.7 8.6 7.5 0.12 12.4 2.1 1.9 2 0 0 2 2 2 0 CoA-binding domain DUF3328 PF11807.8 KLO18218.1 - 2.8e-14 53.4 0.2 3.7e-14 53.0 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PsbN PF02468.15 KLO18218.1 - 0.04 13.8 0.4 0.1 12.5 0.4 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) DUF3328 PF11807.8 KLO18219.1 - 4.4e-16 59.3 0.1 5.5e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PHA-1 PF06542.11 KLO18221.1 - 0.059 12.2 0.4 0.07 12.0 0.4 1.0 1 0 0 1 1 1 0 Regulator protein PHA-1 DUF3328 PF11807.8 KLO18222.1 - 7.2e-15 55.4 0.0 2e-14 53.9 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) F-box-like PF12937.7 KLO18223.1 - 5.3e-07 29.4 1.2 1.5e-05 24.8 0.4 3.1 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO18224.1 - 0.021 14.7 3.3 0.05 13.5 1.5 2.7 2 1 0 2 2 2 0 F-box-like vATP-synt_E PF01991.18 KLO18226.1 - 1.8e-60 203.8 11.6 2e-60 203.6 11.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Afaf PF15339.6 KLO18226.1 - 0.0075 16.0 3.4 0.0086 15.8 2.7 1.4 2 0 0 2 2 2 1 Acrosome formation-associated factor Helicase_RecD PF05127.14 KLO18226.1 - 0.23 11.3 2.3 0.17 11.7 0.4 1.7 1 1 1 2 2 2 0 Helicase GLTP PF08718.11 KLO18226.1 - 0.6 10.4 4.6 1.1 9.5 4.5 1.5 1 1 0 1 1 1 0 Glycolipid transfer protein (GLTP) ubiquitin PF00240.23 KLO18227.1 - 3.1e-17 62.1 0.1 4.9e-17 61.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KLO18227.1 - 5.1e-11 42.3 0.3 5.1e-11 42.3 0.3 2.3 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.8 KLO18227.1 - 2.9e-08 33.4 0.1 4.7e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KLO18227.1 - 8.1e-05 23.1 0.0 0.00018 22.0 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain RPN13_C PF16550.5 KLO18227.1 - 0.053 13.7 4.5 0.11 12.7 3.3 2.0 1 1 1 2 2 2 0 UCH-binding domain Rad60-SLD_2 PF13881.6 KLO18227.1 - 0.054 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KLO18227.1 - 0.075 13.1 0.9 2.9 8.0 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-like domain GerD PF17898.1 KLO18227.1 - 1.6 8.7 9.5 19 5.2 9.5 2.2 1 1 0 1 1 1 0 Spore germination GerD central core domain Mss4 PF04421.13 KLO18228.1 - 7.1e-15 54.9 0.0 1.7e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Mss4 protein Acetyltransf_1 PF00583.25 KLO18228.1 - 9.3e-09 35.5 0.0 1.7e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KLO18228.1 - 5.6e-06 26.7 0.0 1.2e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO18228.1 - 2.2e-05 24.4 0.0 8.4e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KLO18228.1 - 0.00012 22.2 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KLO18228.1 - 0.008 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase FAM153 PF15722.5 KLO18228.1 - 0.063 13.6 0.1 0.18 12.2 0.1 1.7 1 0 0 1 1 1 0 FAM153 family FR47 PF08445.10 KLO18228.1 - 0.073 13.1 0.0 0.35 10.9 0.0 2.1 2 1 0 2 2 2 0 FR47-like protein DUF5641 PF18701.1 KLO18228.1 - 0.21 11.8 0.0 0.41 10.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5641) Glyco_hydro_16 PF00722.21 KLO18229.1 - 0.00064 19.2 0.0 0.0013 18.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Phage_holin_7_1 PF16081.5 KLO18229.1 - 0.16 12.2 0.1 0.23 11.6 0.1 1.2 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family RCC1 PF00415.18 KLO18230.1 - 4.3e-19 68.9 1.4 0.00069 20.2 0.4 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KLO18230.1 - 6.9e-17 61.7 0.0 2.8e-08 34.0 0.0 3.4 2 2 1 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 KLO18230.1 - 4.2e-08 33.6 0.7 2.1e-07 31.3 0.3 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 KLO18230.1 - 1e-07 31.6 0.0 1e-07 31.6 0.0 4.1 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 KLO18230.1 - 1.1e-07 32.3 0.0 2.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KLO18230.1 - 0.00025 21.3 0.2 0.57 10.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KLO18230.1 - 0.00098 19.4 0.3 0.018 15.4 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KLO18230.1 - 0.0015 18.9 0.6 0.057 13.9 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat EKLF_TAD1 PF16832.5 KLO18230.1 - 0.052 13.4 4.1 0.13 12.1 4.1 1.7 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Ras PF00071.22 KLO18231.1 - 8.5e-34 116.5 0.1 1e-33 116.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO18231.1 - 2.3e-25 89.1 0.0 3.8e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO18231.1 - 8.5e-08 31.8 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KLO18231.1 - 1.2e-06 28.1 0.2 1.5e-06 27.7 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KLO18231.1 - 0.014 14.3 0.2 3.3 6.4 0.0 2.3 2 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 KLO18231.1 - 0.032 13.4 1.2 0.16 11.1 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 KLO18231.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 KLO18231.1 - 0.18 11.2 0.0 2.7 7.4 0.0 2.4 2 1 0 2 2 2 0 Bacterial TniB protein CD24 PF14984.6 KLO18231.1 - 0.4 10.9 11.2 0.76 10.0 11.2 1.5 1 0 0 1 1 1 0 CD24 protein Aldo_ket_red PF00248.21 KLO18232.1 - 2.9e-48 164.6 0.0 1.4e-39 136.0 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family F-box-like PF12937.7 KLO18233.1 - 0.00028 20.7 0.6 0.00071 19.4 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO18233.1 - 0.00062 19.6 1.3 0.00062 19.6 1.3 2.2 2 0 0 2 2 2 1 F-box domain Zn_clus PF00172.18 KLO18236.1 - 5.2e-08 32.9 11.3 9.6e-08 32.0 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KLO18236.1 - 5.6e-05 22.3 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Copper-fist PF00649.18 KLO18236.1 - 5.9 6.5 9.0 0.064 12.8 0.7 2.0 2 0 0 2 2 2 0 Copper fist DNA binding domain Tfb5 PF06331.12 KLO18237.1 - 6.8e-22 77.2 1.3 7.3e-22 77.1 1.3 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Rib_5-P_isom_A PF06026.14 KLO18238.1 - 2.5e-59 199.7 0.0 3.1e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KLO18238.1 - 0.096 12.6 0.0 7.9 6.4 0.0 2.1 1 1 1 2 2 2 0 DeoR C terminal sensor domain Peptidase_M50 PF02163.22 KLO18240.1 - 3.9e-06 26.3 0.1 5.6e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M50 HNH_2 PF13391.6 KLO18241.1 - 1.1e-08 35.1 0.1 3e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease Peptidase_M50 PF02163.22 KLO18242.1 - 9.3e-06 25.1 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M50 NPR3 PF03666.13 KLO18243.1 - 2.7e-90 303.4 0.0 4.7e-69 233.4 0.0 2.5 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 HTH_28 PF13518.6 KLO18243.1 - 0.0031 17.6 0.1 0.0092 16.1 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Glyco_hydro_18 PF00704.28 KLO18244.1 - 7e-16 58.8 0.5 1.3e-15 58.0 0.5 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KLO18245.1 - 9.8e-72 242.3 7.6 1.3e-71 241.9 7.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KLO18245.1 - 0.00087 19.7 10.7 0.0015 19.0 6.8 3.0 2 0 0 2 2 2 1 Carbohydrate binding domain PknH_C PF14032.6 KLO18245.1 - 0.67 9.8 6.6 6.7 6.5 0.2 2.5 1 1 1 2 2 2 0 PknH-like extracellular domain rRNA_proc-arch PF13234.6 KLO18246.1 - 6.6e-87 291.9 1.0 8e-87 291.6 0.0 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KLO18246.1 - 6.2e-55 185.3 2.1 1.8e-54 183.8 2.1 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KLO18246.1 - 4.2e-18 65.7 0.7 2.6e-17 63.2 0.1 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO18246.1 - 2.6e-07 31.0 0.0 1.2e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO18246.1 - 0.00022 21.3 0.0 0.00065 19.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KLO18246.1 - 0.0032 16.6 0.0 0.024 13.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 KLO18246.1 - 0.027 14.7 0.0 0.1 12.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KLO18246.1 - 0.046 13.2 0.0 0.68 9.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Pkinase PF00069.25 KLO18247.1 - 2.2e-72 243.6 0.0 2.8e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO18247.1 - 8.6e-35 120.3 0.0 1.2e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KLO18247.1 - 9.5e-13 48.6 1.2 2.1e-12 47.5 1.2 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KLO18247.1 - 5.3e-06 25.6 0.0 7.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KLO18247.1 - 0.0011 18.3 0.0 0.0028 17.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 KLO18247.1 - 0.0071 16.6 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain FTA2 PF13095.6 KLO18247.1 - 0.073 12.7 0.0 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 GATase PF00117.28 KLO18248.1 - 2.7e-10 40.4 0.0 2.1e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I GCP_N_terminal PF17681.1 KLO18249.1 - 3.5e-61 207.5 0.0 6.5e-61 206.6 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KLO18249.1 - 1.1e-47 163.0 0.2 2.6e-46 158.5 0.0 2.1 2 0 0 2 2 2 2 Gamma tubulin complex component C-terminal F-box PF00646.33 KLO18251.1 - 1.5e-05 24.8 0.1 5.6e-05 22.9 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO18251.1 - 2.9e-05 23.8 0.1 7.6e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like S4 PF01479.25 KLO18252.1 - 1.2e-10 40.9 0.0 2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KLO18252.1 - 0.0068 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 S4 domain SNARE PF05739.19 KLO18253.1 - 0.014 15.4 3.8 0.041 13.9 3.8 1.8 1 1 0 1 1 1 0 SNARE domain CcmD PF04995.14 KLO18253.1 - 0.73 10.0 2.2 1.7 8.8 2.2 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Paf67 PF10255.9 KLO18254.1 - 2.7e-162 540.4 0.0 3.5e-162 540.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 GLTSCR1 PF15249.6 KLO18254.1 - 0.016 15.7 0.1 5.9 7.4 0.0 3.4 3 0 0 3 3 3 0 Conserved region of unknown function on GLTSCR protein PAP_assoc PF03828.19 KLO18255.1 - 1e-06 28.8 0.0 5.9e-05 23.2 0.0 3.6 4 0 0 4 4 4 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KLO18255.1 - 4.5e-05 23.7 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.11 KLO18255.1 - 0.0011 19.2 0.0 0.61 10.4 0.0 2.6 2 0 0 2 2 2 2 tRNA nucleotidyltransferase, second domain Nrap_D2 PF17403.2 KLO18255.1 - 0.0028 17.4 0.0 0.01 15.6 0.0 1.9 3 0 0 3 3 3 1 Nrap protein PAP/OAS-like domain GATase PF00117.28 KLO18257.1 - 3.1e-09 36.9 0.0 1.3e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I HTS PF04204.16 KLO18257.1 - 0.07 12.1 0.0 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Homoserine O-succinyltransferase Peptidase_C26 PF07722.13 KLO18257.1 - 0.096 12.4 0.4 0.44 10.3 0.2 2.3 2 1 0 2 2 2 0 Peptidase C26 Glyco_hydro_16 PF00722.21 KLO18258.1 - 0.075 12.5 0.0 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 KLO18259.1 - 0.017 14.6 0.0 0.044 13.3 0.0 1.7 1 1 0 2 2 2 0 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 KLO18260.1 - 0.021 14.3 0.1 0.072 12.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 16 SPT_ssu-like PF11779.8 KLO18261.1 - 1.9e-14 53.0 6.5 2.7e-14 52.5 6.5 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Ferlin_C PF16165.5 KLO18261.1 - 0.0011 18.9 1.7 0.017 15.1 1.0 2.1 2 0 0 2 2 2 1 Ferlin C-terminus DUF4481 PF14800.6 KLO18261.1 - 0.13 11.7 2.9 0.18 11.3 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) DUF2127 PF09900.9 KLO18261.1 - 0.2 11.9 4.4 0.26 11.5 4.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) Methyltransf_11 PF08241.12 KLO18265.1 - 8.3e-18 64.8 0.0 1.6e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO18265.1 - 4e-15 56.3 0.0 8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO18265.1 - 2.7e-08 34.5 0.0 7.2e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO18265.1 - 6.5e-08 32.5 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO18265.1 - 0.00015 21.2 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KLO18265.1 - 0.00038 20.3 0.0 0.00061 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Glyco_hydro_18 PF00704.28 KLO18266.1 - 2.1e-15 57.3 1.2 4e-15 56.3 1.2 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DctP PF03480.13 KLO18266.1 - 0.034 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 GCN5L1 PF06320.13 KLO18267.1 - 0.052 13.7 1.0 0.12 12.5 1.0 1.7 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) PilN PF05137.13 KLO18270.1 - 0.16 12.1 0.6 0.89 9.7 0.1 2.4 2 1 0 2 2 2 0 Fimbrial assembly protein (PilN) Actin PF00022.19 KLO18272.1 - 5.2e-94 315.1 0.0 3.1e-93 312.6 0.0 1.8 1 1 0 1 1 1 1 Actin PilM_2 PF11104.8 KLO18272.1 - 0.00038 19.6 0.0 0.089 11.8 0.0 2.1 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; MreB_Mbl PF06723.13 KLO18272.1 - 0.0005 19.0 0.0 0.73 8.6 0.0 2.7 3 0 0 3 3 3 2 MreB/Mbl protein AAA_18 PF13238.6 KLO18273.1 - 0.00065 20.2 0.0 0.0012 19.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KLO18273.1 - 0.0083 16.3 0.0 0.047 13.8 0.0 2.0 1 1 0 1 1 1 1 Shikimate kinase DUF4715 PF15835.5 KLO18273.1 - 0.049 13.7 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) AGOG PF09171.10 KLO18273.1 - 0.13 11.5 0.1 0.28 10.5 0.0 1.5 2 0 0 2 2 2 0 N-glycosylase/DNA lyase STAT_alpha PF01017.20 KLO18274.1 - 0.04 13.8 2.3 3.1 7.7 0.2 2.7 2 1 1 3 3 3 0 STAT protein, all-alpha domain Glyco_transf_49 PF13896.6 KLO18276.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan Tri3 PF07428.11 KLO18277.1 - 0.1 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 NACHT PF05729.12 KLO18278.1 - 4.2e-08 33.3 0.0 1.6e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO18278.1 - 6.2e-05 23.4 0.1 0.00026 21.4 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain HTH_Mga PF08280.11 KLO18278.1 - 0.26 11.3 1.3 10 6.2 0.0 2.5 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Glyco_hydro_16 PF00722.21 KLO18280.1 - 0.068 12.6 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 16 Myosin_head PF00063.21 KLO18281.1 - 2.7e-256 852.1 0.1 1.2e-255 850.0 0.0 2.2 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KLO18281.1 - 6.1e-11 40.9 273.1 2.6e-06 25.6 127.2 4.6 2 2 2 4 4 4 3 Myosin tail Myosin_N PF02736.19 KLO18281.1 - 1.6e-07 31.1 7.4 3.6e-07 29.9 7.4 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.21 KLO18281.1 - 0.0015 18.2 34.2 0.0015 18.2 34.2 10.8 3 2 5 9 9 9 5 Intermediate filament protein AAA_22 PF13401.6 KLO18281.1 - 0.26 11.5 0.0 0.26 11.5 0.0 4.8 5 1 0 5 5 5 0 AAA domain Chromo PF00385.24 KLO18284.1 - 0.00077 19.3 4.6 0.0008 19.3 2.6 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain FAD_binding_3 PF01494.19 KLO18285.1 - 0.0048 16.2 0.1 0.0092 15.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Peptidase_M14 PF00246.24 KLO18288.1 - 4.6e-63 213.7 0.0 5.6e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase ATG13 PF10033.9 KLO18289.1 - 4.6e-42 144.4 0.0 8.5e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 ADH_N PF08240.12 KLO18290.1 - 5.8e-30 103.4 0.3 5.8e-30 103.4 0.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO18290.1 - 5.9e-13 48.9 0.0 1.5e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KLO18290.1 - 3.4e-11 43.0 0.0 5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KLO18290.1 - 1.9e-05 25.7 0.0 3.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KLO18290.1 - 0.00013 21.4 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ADH_N_assoc PF13823.6 KLO18290.1 - 0.00027 20.8 0.1 0.00065 19.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Pyr_redox_2 PF07992.14 KLO18290.1 - 0.023 14.0 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KLO18290.1 - 0.13 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KLO18290.1 - 0.13 12.5 0.1 0.39 11.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KLO18290.1 - 0.17 12.5 0.0 0.42 11.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HAD_2 PF13419.6 KLO18293.1 - 1.6e-08 34.9 0.3 2e-07 31.3 0.3 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KLO18293.1 - 0.00053 20.3 0.0 0.0017 18.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO18293.1 - 0.0033 17.4 0.0 0.0058 16.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Ribosomal_L38e PF01781.18 KLO18295.1 - 4.9e-16 58.6 2.9 5.6e-16 58.4 2.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DSBA PF01323.20 KLO18296.1 - 2.2e-34 118.9 0.2 2.5e-34 118.7 0.2 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KLO18296.1 - 0.0014 18.8 0.1 0.037 14.2 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin DUF1525 PF07511.11 KLO18296.1 - 0.0018 18.4 0.1 0.0035 17.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1525) Thioredoxin_3 PF13192.6 KLO18296.1 - 0.0019 18.2 0.1 0.12 12.4 0.1 2.3 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.6 KLO18296.1 - 0.27 11.7 1.7 2.7 8.5 1.7 2.6 1 1 0 1 1 1 0 Thioredoxin-like domain GFA PF04828.14 KLO18297.1 - 5.7e-10 39.4 0.3 8.5e-10 38.8 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Sgf11 PF08209.11 KLO18297.1 - 0.22 11.1 7.4 1 9.0 2.1 2.9 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) CBM_20 PF00686.19 KLO18298.1 - 2.9e-32 110.4 0.4 6.2e-32 109.4 0.4 1.6 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase_C PF02806.18 KLO18298.1 - 1.1e-13 51.4 0.3 3.7e-13 49.8 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KLO18298.1 - 2e-09 37.5 0.0 1.9e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, catalytic domain RRM_1 PF00076.22 KLO18300.1 - 2.5e-56 187.4 0.0 4.2e-15 55.3 0.0 5.9 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KLO18300.1 - 1.7e-05 24.9 0.0 0.36 11.0 0.0 3.8 4 0 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KLO18300.1 - 0.045 13.8 0.0 22 5.1 0.0 3.4 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KLO18300.1 - 0.077 12.8 0.0 3.3 7.5 0.0 3.1 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_8 PF11835.8 KLO18300.1 - 0.21 11.8 0.0 8.1 6.7 0.0 3.2 3 0 0 3 3 3 0 RRM-like domain MFS_1 PF07690.16 KLO18301.1 - 1.1e-22 80.4 43.7 4.4e-19 68.6 29.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 KLO18301.1 - 1.5 8.3 4.4 1.7 8.1 0.2 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family ABC2_membrane PF01061.24 KLO18303.1 - 2.1e-67 226.6 50.3 1e-37 129.6 13.9 3.1 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KLO18303.1 - 4e-38 131.0 0.0 9.4e-19 68.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KLO18303.1 - 1.7e-34 117.6 3.6 2.9e-27 94.4 0.2 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KLO18303.1 - 2.1e-07 31.4 0.1 5.6e-07 30.1 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_22 PF13401.6 KLO18303.1 - 2.6e-07 31.0 0.1 0.0093 16.2 0.2 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KLO18303.1 - 9.1e-07 29.4 0.3 0.01 16.2 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KLO18303.1 - 1.7e-06 28.1 0.2 0.00011 22.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KLO18303.1 - 0.00032 20.4 0.5 0.24 11.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KLO18303.1 - 0.00073 19.6 0.2 0.48 10.5 0.2 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KLO18303.1 - 0.0008 19.3 3.7 0.68 9.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KLO18303.1 - 0.0019 17.8 0.1 0.079 12.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KLO18303.1 - 0.0033 16.6 36.1 0.045 12.9 16.7 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein NACHT PF05729.12 KLO18303.1 - 0.011 15.7 0.5 1.8 8.5 0.3 2.6 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 KLO18303.1 - 0.011 15.9 0.0 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KLO18303.1 - 0.013 16.0 0.0 7.5 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KLO18303.1 - 0.015 15.0 2.8 0.47 10.2 0.3 2.7 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KLO18303.1 - 0.016 15.0 0.0 7.1 6.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KLO18303.1 - 0.025 14.8 0.1 2.6 8.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KLO18303.1 - 0.043 13.1 0.0 7.4 5.7 0.0 2.2 2 0 0 2 2 2 0 Septin AAA PF00004.29 KLO18303.1 - 0.062 13.7 0.0 24 5.3 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 KLO18303.1 - 0.073 12.5 0.0 1.1 8.7 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KLO18303.1 - 0.15 12.3 0.0 8.6 6.7 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 KLO18303.1 - 0.22 11.1 2.7 3.8 7.1 0.7 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KLO18303.1 - 0.43 11.1 1.1 0.63 10.5 0.1 1.7 2 0 0 2 2 1 0 AAA domain FeoB_N PF02421.18 KLO18303.1 - 0.51 9.8 1.5 6.3 6.3 0.2 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B Ribonuclease PF00545.20 KLO18305.1 - 5.9e-06 26.9 0.0 8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 ribonuclease FAD_binding_3 PF01494.19 KLO18306.1 - 1.5e-14 54.0 0.0 2.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO18306.1 - 0.00021 20.6 0.2 0.033 13.4 0.3 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO18306.1 - 0.00027 21.1 0.2 0.00056 20.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KLO18306.1 - 0.0029 16.7 0.7 0.005 16.0 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KLO18306.1 - 0.0043 16.4 0.2 0.0043 16.4 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KLO18306.1 - 0.017 14.7 0.8 6.5 6.2 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KLO18306.1 - 0.05 14.2 0.1 0.16 12.5 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO18306.1 - 0.056 12.7 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO18306.1 - 0.078 11.7 0.1 0.17 10.5 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.24 KLO18306.1 - 0.19 10.9 2.1 0.82 8.9 0.1 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase DUF2127 PF09900.9 KLO18307.1 - 0.0076 16.5 0.6 0.039 14.2 0.5 2.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2127) Pkinase_Tyr PF07714.17 KLO18308.1 - 1.1e-42 146.2 0.0 1.7e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO18308.1 - 1.2e-39 136.2 0.0 1.8e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KLO18308.1 - 0.00015 20.7 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO18308.1 - 0.037 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KLO18308.1 - 0.074 12.6 0.0 0.75 9.4 0.0 2.0 2 0 0 2 2 2 0 RIO1 family ATG13 PF10033.9 KLO18309.1 - 2.1e-18 66.9 0.0 2.8e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 13 Abhydrolase_2 PF02230.16 KLO18310.1 - 9.4e-59 198.8 0.0 5.1e-58 196.4 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KLO18310.1 - 0.00027 20.3 0.3 0.55 9.4 0.1 3.4 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KLO18310.1 - 0.0021 18.7 0.0 0.0025 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KLO18310.1 - 0.0027 17.4 0.0 0.0055 16.4 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KLO18310.1 - 0.039 13.6 0.2 0.15 11.7 0.2 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KLO18310.1 - 0.061 12.9 0.0 0.069 12.8 0.0 1.3 1 1 0 1 1 1 0 Putative esterase Trp_halogenase PF04820.14 KLO18311.1 - 2.4e-30 105.8 0.4 4.4e-16 58.8 0.4 2.3 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KLO18311.1 - 2.5e-15 56.6 0.2 1.1e-14 54.5 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KLO18311.1 - 4.7e-07 29.5 0.0 7.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO18311.1 - 7.6e-05 22.1 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO18311.1 - 0.00012 21.8 0.4 0.41 10.2 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO18311.1 - 0.00023 21.4 0.1 0.00076 19.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KLO18311.1 - 0.0024 17.0 0.0 0.0048 16.0 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KLO18311.1 - 0.019 14.1 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KLO18311.1 - 0.019 13.7 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 KLO18311.1 - 0.04 13.1 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family EBP PF05241.12 KLO18312.1 - 0.39 10.2 14.2 0.69 9.4 14.2 1.5 1 1 0 1 1 1 0 Emopamil binding protein NUC173 PF08161.12 KLO18313.1 - 0.056 13.1 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 NUC173 domain Phosducin PF02114.16 KLO18317.1 - 5.3e-11 42.0 0.0 1.4e-05 24.2 0.0 2.3 2 1 0 2 2 2 2 Phosducin adh_short_C2 PF13561.6 KLO18318.1 - 2.1e-58 197.7 0.2 2.8e-58 197.2 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO18318.1 - 3.4e-52 176.8 0.2 4.4e-52 176.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO18318.1 - 3.9e-12 46.5 0.5 5.6e-12 45.9 0.5 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KLO18318.1 - 0.0068 15.5 0.7 0.012 14.6 0.7 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 KLO18318.1 - 0.013 15.4 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_pol_Rpb2_3 PF04565.16 KLO18320.1 - 0.045 13.9 0.3 0.13 12.4 0.2 1.9 2 1 0 2 2 2 0 RNA polymerase Rpb2, domain 3 GPI-anchored PF10342.9 KLO18321.1 - 8.5e-08 32.9 0.4 8.5e-08 32.9 0.4 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family vATP-synt_E PF01991.18 KLO18323.1 - 0.2 11.1 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Fungal_trans PF04082.18 KLO18324.1 - 1.2e-08 34.4 0.1 1.9e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO18324.1 - 5.8e-06 26.3 11.1 1.1e-05 25.4 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TSC22 PF01166.18 KLO18324.1 - 0.016 15.5 0.5 0.21 11.9 0.3 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family RHD3 PF05879.12 KLO18325.1 - 6.4e-247 821.4 6.1 8.2e-247 821.1 6.1 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KLO18325.1 - 2.3e-06 27.1 0.2 6.6e-06 25.6 0.2 1.8 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 KLO18325.1 - 1.3e-05 25.3 0.0 3.4e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KLO18325.1 - 4.1e-05 23.7 0.0 9.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 KLO18325.1 - 0.0042 17.3 0.0 0.016 15.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AMP-binding PF00501.28 KLO18326.1 - 1.3e-67 228.3 0.0 2.2e-67 227.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ECH_1 PF00378.20 KLO18326.1 - 4.8e-43 147.3 0.0 6.5e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KLO18326.1 - 7.3e-23 81.6 0.1 1.6e-22 80.5 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase AMP-binding_C PF13193.6 KLO18326.1 - 9.6e-14 52.1 0.0 1.9e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KLO18327.1 - 1e-24 87.0 0.0 1.7e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO18327.1 - 2.5e-06 27.5 7.5 2.5e-06 27.5 7.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KLO18327.1 - 0.0029 16.5 0.0 0.0051 15.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain R3H PF01424.22 KLO18329.1 - 7.7e-10 38.6 0.0 2.1e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KLO18329.1 - 1.6e-06 27.9 0.8 4.9e-06 26.3 0.8 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KLO18329.1 - 0.00084 19.4 1.4 0.0019 18.3 0.1 2.4 2 0 0 2 2 2 1 G-patch domain FA_hydroxylase PF04116.13 KLO18330.1 - 5.3e-25 88.3 16.8 7.6e-24 84.6 10.4 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily HSP20 PF00011.21 KLO18331.1 - 0.002 18.2 0.0 0.034 14.3 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KLO18331.1 - 0.0073 15.8 0.0 0.014 14.9 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Nkap_C PF06047.11 KLO18332.1 - 1.3e-41 140.8 3.0 1.3e-41 140.8 3.0 2.9 2 1 1 3 3 3 1 NF-kappa-B-activating protein C-terminal domain FKBP_C PF00254.28 KLO18333.1 - 4.3e-33 113.5 0.0 5.3e-33 113.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ribosomal_L39 PF00832.20 KLO18334.1 - 4e-22 77.6 8.4 4.6e-22 77.4 8.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein FAT PF02259.23 KLO18336.1 - 3e-112 375.3 11.5 7.1e-112 374.0 11.5 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KLO18336.1 - 1.1e-67 228.5 0.0 3.4e-67 226.9 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KLO18336.1 - 1.1e-55 187.9 1.7 4e-49 166.6 0.2 6.1 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KLO18336.1 - 8.3e-41 138.4 1.3 8.3e-41 138.4 1.3 4.1 4 0 0 4 4 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 KLO18336.1 - 7.6e-16 58.3 17.9 0.02 15.3 0.1 10.1 9 1 3 12 12 10 5 HEAT repeats FATC PF02260.20 KLO18336.1 - 2.3e-15 56.1 0.6 8.8e-15 54.2 0.6 2.1 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KLO18336.1 - 6.1e-11 41.6 14.2 0.49 10.8 0.1 11.4 13 0 0 13 13 9 2 HEAT repeat TPR_19 PF14559.6 KLO18336.1 - 6.9e-06 26.5 0.1 0.11 13.0 0.1 3.6 3 0 0 3 3 2 2 Tetratricopeptide repeat CLASP_N PF12348.8 KLO18336.1 - 7.8e-05 22.3 4.1 3.9 7.0 0.0 5.6 4 1 0 4 4 4 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 KLO18336.1 - 0.00018 22.0 1.9 1.6 9.4 0.0 6.4 5 1 2 7 7 7 1 Vacuolar 14 Fab1-binding region UME PF08064.13 KLO18336.1 - 0.00021 21.2 12.3 0.15 12.0 0.2 6.4 6 0 0 6 6 5 1 UME (NUC010) domain HEAT_EZ PF13513.6 KLO18336.1 - 0.0016 18.9 10.2 0.5 10.9 0.2 7.5 9 0 0 9 9 6 1 HEAT-like repeat ANAPC3 PF12895.7 KLO18336.1 - 0.002 18.3 0.2 0.53 10.5 0.0 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KLO18336.1 - 0.0044 16.9 6.5 0.52 10.5 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KLO18336.1 - 0.0077 16.9 0.2 2.1 9.1 0.0 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat Cnd1 PF12717.7 KLO18336.1 - 0.03 14.4 11.3 0.14 12.2 0.1 5.7 6 1 0 7 7 6 0 non-SMC mitotic condensation complex subunit 1 TPR_14 PF13428.6 KLO18336.1 - 0.045 14.6 1.5 4.3 8.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KLO18336.1 - 0.073 13.2 4.9 0.62 10.3 0.2 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TilS PF09179.11 KLO18336.1 - 0.091 13.3 0.7 0.48 11.0 0.7 2.4 1 0 0 1 1 1 0 TilS substrate binding domain TPR_1 PF00515.28 KLO18336.1 - 0.12 12.2 0.3 0.97 9.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TAFH PF07531.14 KLO18336.1 - 0.68 10.1 2.4 21 5.3 0.1 3.7 3 0 0 3 3 3 0 NHR1 homology to TAF TPR_6 PF13174.6 KLO18336.1 - 1.6 9.5 4.9 1.8 9.4 0.1 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat CHD5 PF04420.14 KLO18337.1 - 1.4e-57 194.0 0.5 1.6e-57 193.8 0.5 1.1 1 0 0 1 1 1 1 CHD5-like protein Malate_synthase PF01274.22 KLO18338.1 - 5.7e-195 648.5 0.0 7.5e-195 648.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase OsmC PF02566.19 KLO18339.1 - 8e-14 51.9 0.0 1.1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein Glycophorin_A PF01102.18 KLO18340.1 - 0.041 14.1 4.2 0.035 14.3 2.8 1.6 1 1 1 2 2 2 0 Glycophorin A DNA_pol_viral_N PF00242.17 KLO18340.1 - 3.6 7.0 9.7 3.7 6.9 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain AF-4 PF05110.13 KLO18340.1 - 5.2 5.0 8.7 5.4 5.0 8.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Zn_clus PF00172.18 KLO18341.1 - 0.0073 16.4 10.5 0.013 15.6 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAT PF02259.23 KLO18342.1 - 2.6e-98 329.5 8.6 6.3e-98 328.2 8.6 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KLO18342.1 - 2.1e-67 227.6 0.0 5.5e-67 226.2 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KLO18342.1 - 1.7e-42 145.1 12.6 1.2e-40 139.0 0.2 5.6 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KLO18342.1 - 3.3e-28 98.0 0.2 3.3e-28 98.0 0.2 2.5 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 KLO18342.1 - 2.3e-17 62.5 0.5 6.2e-17 61.1 0.5 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KLO18342.1 - 1.9e-15 57.0 4.6 2.3e-05 24.7 0.1 8.3 8 1 1 9 9 9 3 HEAT repeats HEAT PF02985.22 KLO18342.1 - 1.1e-10 40.8 9.1 1.3 9.4 0.1 8.4 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.6 KLO18342.1 - 1.2e-05 25.7 11.8 0.11 13.0 0.4 8.7 11 0 0 11 11 9 1 HEAT-like repeat UME PF08064.13 KLO18342.1 - 3.5e-05 23.7 5.7 0.0052 16.7 0.0 5.7 4 2 1 5 5 5 2 UME (NUC010) domain TPR_19 PF14559.6 KLO18342.1 - 9e-05 22.9 0.0 0.067 13.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Cohesin_HEAT PF12765.7 KLO18342.1 - 0.064 13.6 0.8 9.8 6.6 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Nipped-B_C PF12830.7 KLO18342.1 - 0.079 12.9 0.0 2.5 8.0 0.0 3.0 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Telomere_reg-2 PF10193.9 KLO18342.1 - 0.099 13.1 6.0 4.3 7.8 0.1 4.4 4 0 0 4 4 3 0 Telomere length regulation protein TPR_7 PF13176.6 KLO18342.1 - 0.42 10.7 7.5 1.1e+02 3.1 0.1 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MMS19_C PF12460.8 KLO18342.1 - 0.69 9.0 6.0 19 4.2 0.9 4.3 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal Fungal_trans PF04082.18 KLO18343.1 - 1.1e-07 31.1 0.1 2e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO18343.1 - 1.4e-07 31.5 11.4 2.3e-07 30.8 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain W2 PF02020.18 KLO18344.1 - 1.9e-18 66.3 0.7 1.5e-17 63.5 1.0 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon HD_3 PF13023.6 KLO18344.1 - 0.016 15.2 0.1 0.032 14.2 0.1 1.5 1 0 0 1 1 1 0 HD domain zf-C2H2_aberr PF17017.5 KLO18344.1 - 0.061 13.5 0.4 0.12 12.5 0.4 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger Aldo_ket_red PF00248.21 KLO18345.1 - 3.6e-51 174.1 0.0 3.1e-35 121.8 0.0 2.5 2 1 1 3 3 3 2 Aldo/keto reductase family Mnd1 PF03962.15 KLO18345.1 - 2.4e-15 56.6 0.9 5.6e-15 55.4 0.2 2.0 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 KLO18345.1 - 2e-11 43.8 0.0 6.6e-11 42.1 0.0 2.0 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Spc7 PF08317.11 KLO18345.1 - 0.00043 19.3 1.3 0.00062 18.7 1.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4600 PF15372.6 KLO18345.1 - 0.0037 17.7 0.3 0.0064 16.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) Glyco_hydro_28 PF00295.17 KLO18346.1 - 1.3e-61 208.4 20.9 1.6e-61 208.2 20.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ASH PF15780.5 KLO18346.1 - 0.069 13.4 1.2 14 5.9 0.1 3.1 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin BRCT_2 PF16589.5 KLO18347.1 - 3.6e-06 27.3 0.0 7.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KLO18347.1 - 0.0046 17.3 0.0 0.008 16.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rap1-DNA-bind PF09197.10 KLO18347.1 - 0.014 16.0 2.6 2.9 8.5 0.4 3.3 3 0 0 3 3 3 0 Rap1, DNA-binding PIF1 PF05970.14 KLO18351.1 - 9e-14 51.4 0.0 9.6e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KLO18351.1 - 1.6e-07 31.3 0.0 1.8e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO18351.1 - 0.00014 22.2 0.0 0.0003 21.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KLO18351.1 - 0.0011 18.2 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KLO18351.1 - 0.0045 17.4 0.0 0.0046 17.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO18351.1 - 0.012 15.9 0.1 0.018 15.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KLO18351.1 - 0.13 11.6 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KLO18351.1 - 0.16 11.8 0.1 0.19 11.6 0.1 1.4 1 1 0 1 1 1 0 NACHT domain UvrD_C_2 PF13538.6 KLO18352.1 - 0.0095 15.7 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PH_10 PF15411.6 KLO18354.1 - 3.5e-39 133.8 0.0 7.6e-39 132.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KLO18354.1 - 1.2e-33 116.9 0.2 2.1e-33 116.1 0.2 1.5 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 KLO18354.1 - 1.9e-15 56.8 0.2 3.7e-15 56.0 0.2 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 KLO18354.1 - 1e-14 54.2 0.0 2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 PB1 domain PhyH PF05721.13 KLO18355.1 - 6.6e-46 157.2 0.0 8.1e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) GA PF01468.17 KLO18355.1 - 0.015 15.5 0.1 0.031 14.5 0.1 1.4 1 0 0 1 1 1 0 GA module LAGLIDADG_3 PF14528.6 KLO18355.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 LAGLIDADG-like domain HK PF02110.15 KLO18356.1 - 6e-73 245.3 4.4 1.2e-71 241.0 4.4 2.1 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KLO18356.1 - 5.6e-56 188.7 1.2 2.6e-55 186.6 0.1 2.6 3 0 0 3 3 3 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 KLO18356.1 - 0.023 14.1 1.4 2.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Carbohydrate kinase Mcl1_mid PF12341.8 KLO18359.1 - 1.5e-93 313.4 0.0 6.6e-93 311.3 0.0 2.0 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KLO18359.1 - 1.2e-13 51.3 13.7 7e-08 33.0 0.4 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO18359.1 - 1.3e-10 41.4 0.2 0.0093 16.2 0.0 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RrnaAD PF00398.20 KLO18360.1 - 1.2e-24 86.8 0.0 1.9e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF726 PF05277.12 KLO18362.1 - 1.7e-85 286.9 3.5 2.3e-85 286.5 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cutinase PF01083.22 KLO18362.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF747 PF05346.11 KLO18363.1 - 1.2e-109 366.6 5.9 1.7e-109 366.2 5.9 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family KIF1B PF12423.8 KLO18364.1 - 0.13 12.7 2.2 0.17 12.3 0.6 1.9 2 0 0 2 2 2 0 Kinesin protein 1B CPSF73-100_C PF11718.8 KLO18365.1 - 1.7e-65 220.6 0.0 2.7e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KLO18365.1 - 6.8e-30 103.6 0.0 1.6e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KLO18365.1 - 2.8e-18 66.7 1.0 5.3e-18 65.7 1.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KLO18365.1 - 2.3e-17 63.0 0.1 8e-17 61.3 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KLO18365.1 - 3.2e-16 59.0 0.1 6.7e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KLO18365.1 - 4.9e-07 29.5 1.6 6.4e-06 25.8 0.6 2.7 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KLO18365.1 - 5.7e-06 26.3 0.1 3.8e-05 23.6 0.1 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_61 PF03443.14 KLO18366.1 - 7.7e-46 156.6 0.0 1e-45 156.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_zinc_N PF00107.26 KLO18367.1 - 1.8e-20 73.2 0.9 3.4e-20 72.3 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KLO18367.1 - 1.6e-13 50.5 0.0 2.8e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KLO18367.1 - 1.3e-07 32.7 0.0 2.6e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CRC_subunit PF08624.10 KLO18369.1 - 8.2e-42 142.9 0.0 1.3e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF5320 PF17253.2 KLO18369.1 - 3 9.0 18.0 0.38 11.9 10.5 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5320) TatD_DNase PF01026.21 KLO18370.1 - 3.7e-42 144.5 0.0 4.7e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase PH_9 PF15410.6 KLO18371.1 - 4.4e-28 98.0 0.0 7.8e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 KLO18371.1 - 6e-28 97.8 0.0 1.8e-27 96.2 0.0 1.7 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 KLO18371.1 - 0.00022 21.7 0.0 0.00079 19.9 0.0 1.9 1 0 0 1 1 1 1 PH domain GATA PF00320.27 KLO18372.1 - 8.1e-18 63.7 3.3 1.5e-17 62.9 3.3 1.5 1 0 0 1 1 1 1 GATA zinc finger Git3 PF11710.8 KLO18373.1 - 1.6e-05 24.8 6.5 3e-05 23.9 6.5 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KLO18373.1 - 0.00028 20.3 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Gastrin PF00918.17 KLO18373.1 - 0.0095 16.9 0.6 0.019 15.9 0.2 1.7 2 0 0 2 2 2 1 Gastrin/cholecystokinin family Peptidase_A22B PF04258.13 KLO18374.1 - 2.7e-72 243.7 8.6 3.7e-72 243.2 8.6 1.0 1 0 0 1 1 1 1 Signal peptide peptidase Dynamitin PF04912.14 KLO18375.1 - 5.4e-62 210.3 2.4 6.9e-62 210.0 2.4 1.1 1 0 0 1 1 1 1 Dynamitin ABC_tran_CTD PF16326.5 KLO18375.1 - 0.27 11.5 1.6 2.5 8.4 0.1 3.2 3 1 0 3 3 3 0 ABC transporter C-terminal domain Pheromone PF08015.11 KLO18375.1 - 0.35 11.9 0.0 0.35 11.9 0.0 3.7 3 2 0 4 4 4 0 Fungal mating-type pheromone Baculo_PEP_C PF04513.12 KLO18375.1 - 0.6 10.1 4.6 18 5.4 0.1 3.3 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 KLO18375.1 - 0.99 9.6 6.7 16 5.6 0.0 3.9 4 1 0 4 4 4 0 Tropomyosin like CLZ PF16526.5 KLO18375.1 - 1.7 9.1 9.2 2 8.8 0.3 4.1 4 1 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FRG2 PF15315.6 KLO18375.1 - 8.1 6.6 12.7 0.07 13.3 3.0 2.3 3 0 0 3 3 3 0 Facioscapulohumeral muscular dystrophy candidate 2 Asparaginase_2 PF01112.18 KLO18376.1 - 3.9e-72 242.9 0.0 7.3e-71 238.7 0.0 2.3 1 1 0 1 1 1 1 Asparaginase G_glu_transpept PF01019.21 KLO18376.1 - 0.0045 15.8 0.1 0.12 11.1 0.3 2.2 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase Mannosyl_trans2 PF04188.13 KLO18377.1 - 1.1e-58 199.7 24.0 1.3e-58 199.4 24.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) XPG_I PF00867.18 KLO18378.1 - 2.9e-19 69.2 0.0 6.6e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 KLO18378.1 - 3.4e-17 63.3 0.0 5.9e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 KLO18378.1 - 2.2e-06 28.0 0.0 8.1e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 XPG N-terminal domain Pex24p PF06398.11 KLO18379.1 - 1.3e-25 90.2 9.2 1.3e-25 90.2 9.2 3.0 2 1 0 2 2 2 1 Integral peroxisomal membrane peroxin DUF4407 PF14362.6 KLO18379.1 - 0.15 11.4 1.6 0.33 10.3 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Q_salvage PF10343.9 KLO18380.1 - 2e-14 53.8 0.0 3.7e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family YqeY PF09424.10 KLO18381.1 - 2e-26 92.8 1.2 2.7e-26 92.4 1.2 1.2 1 0 0 1 1 1 1 Yqey-like protein zf-rbx1 PF12678.7 KLO18382.1 - 1.1e-10 41.6 6.2 4.4e-10 39.7 6.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KLO18382.1 - 1.9e-09 37.7 7.6 6.8e-09 35.9 3.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KLO18382.1 - 3.8e-08 33.1 1.2 9.2e-08 31.8 1.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO18382.1 - 1.6e-06 27.9 3.8 1.6e-06 27.9 3.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO18382.1 - 5e-05 23.1 4.7 0.0006 19.6 1.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO18382.1 - 0.00011 22.2 6.6 0.00064 19.7 6.6 2.2 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KLO18382.1 - 0.00063 19.6 0.6 0.00063 19.6 0.6 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KLO18382.1 - 0.00066 19.3 0.8 0.0014 18.2 0.8 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KLO18382.1 - 0.00072 19.6 1.4 0.0016 18.4 0.6 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KLO18382.1 - 0.0048 16.8 5.6 0.038 13.9 5.9 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 KLO18382.1 - 0.0054 16.5 0.4 0.0054 16.5 0.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 KLO18382.1 - 0.011 15.9 1.3 0.021 15.0 1.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KLO18382.1 - 0.18 12.0 0.2 0.45 10.7 0.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KLO18382.1 - 0.43 10.9 2.5 0.8 10.1 2.5 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KLO18382.1 - 3.8 7.4 5.1 1.1 9.1 1.7 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Amidohydro_3 PF07969.11 KLO18383.1 - 6.9e-85 286.3 0.6 8.5e-85 286.0 0.6 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KLO18383.1 - 7.5e-15 55.1 0.0 1.7e-14 53.9 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase family SNF2_N PF00176.23 KLO18384.1 - 3.4e-55 187.2 0.0 5.6e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO18384.1 - 5e-14 52.6 0.0 9.1e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO18384.1 - 7.7e-12 45.5 0.0 4.3e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KLO18384.1 - 4.2e-08 33.1 0.0 8.8e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KLO18384.1 - 0.0008 18.7 0.6 0.0015 17.7 0.1 1.6 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF2439 PF10382.9 KLO18384.1 - 0.14 12.5 0.2 13 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) Na_H_Exchanger PF00999.21 KLO18385.1 - 3.9e-61 207.0 25.8 4.6e-61 206.7 25.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family LapA_dom PF06305.11 KLO18385.1 - 0.034 13.9 1.1 0.034 13.9 1.1 3.7 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain YrhC PF14143.6 KLO18385.1 - 0.9 9.7 10.7 1.8 8.7 0.2 4.1 4 0 0 4 4 4 0 YrhC-like protein Na_H_Exchanger PF00999.21 KLO18386.1 - 2.3e-56 191.3 26.9 2.6e-56 191.0 26.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DIM PF08194.12 KLO18388.1 - 0.0027 17.9 0.0 0.0082 16.3 0.0 1.9 1 0 0 1 1 1 1 DIM protein EB PF01683.18 KLO18388.1 - 0.36 11.2 37.6 3.8 7.9 0.2 4.5 4 1 0 4 4 4 0 EB module Dickkopf_N PF04706.12 KLO18388.1 - 0.99 9.9 30.0 0.09 13.3 6.6 4.2 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region EGF_2 PF07974.13 KLO18389.1 - 0.47 10.9 17.6 0.68 10.4 2.0 3.6 3 0 0 3 3 3 0 EGF-like domain Laminin_EGF PF00053.24 KLO18389.1 - 5.8 7.1 19.1 0.6 10.3 0.7 3.6 3 0 0 3 3 3 0 Laminin EGF domain DUF1279 PF06916.13 KLO18391.1 - 1.4e-16 60.8 0.2 2.4e-16 60.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) VF530 PF09905.9 KLO18391.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA-binding protein VF530 RPEL PF02755.15 KLO18392.1 - 2.4e-15 55.7 5.4 1.7e-07 30.7 3.1 2.3 2 0 0 2 2 2 2 RPEL repeat DDE_Tnp_IS66 PF03050.14 KLO18392.1 - 0.049 13.1 0.8 0.053 13.0 0.8 1.1 1 0 0 1 1 1 0 Transposase IS66 family AbiEii PF08843.11 KLO18393.1 - 0.012 15.6 0.1 0.02 14.9 0.1 1.7 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Trp_DMAT PF11991.8 KLO18393.1 - 0.026 14.0 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase Dioxygenase_C PF00775.21 KLO18394.1 - 2.1e-43 147.9 0.0 3e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KLO18394.1 - 1.2e-25 89.1 0.0 1.9e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Rax2 PF12768.7 KLO18396.1 - 1.2e-45 155.7 9.2 7.1e-44 149.8 3.9 4.7 5 0 0 5 5 5 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 KLO18396.1 - 1.9e-11 43.4 0.1 4.3e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KLO18396.1 - 2.5e-09 36.9 0.7 6.4e-09 35.5 0.2 2.0 2 0 0 2 2 2 1 Variant SH3 domain Reg_prop PF07494.11 KLO18396.1 - 0.0097 16.0 1.0 0.25 11.7 0.0 3.9 3 0 0 3 3 3 1 Two component regulator propeller DUF5122 PF17164.4 KLO18396.1 - 0.09 13.1 0.0 0.09 13.1 0.0 9.0 8 1 1 9 9 9 0 Domain of unknown function (DUF5122) beta-propeller Tmemb_9 PF05434.11 KLO18396.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 TMEM9 Kelch_2 PF07646.15 KLO18396.1 - 5.7 7.1 5.9 96 3.2 0.0 4.9 5 0 0 5 5 5 0 Kelch motif zf-C2H2_2 PF12756.7 KLO18397.1 - 3.1e-36 123.7 9.5 2.1e-30 105.1 0.3 3.2 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KLO18397.1 - 1.3e-10 41.3 14.3 1.3e-08 34.9 1.9 3.6 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KLO18397.1 - 5.1e-07 29.9 2.6 5.1e-07 29.9 2.6 2.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KLO18397.1 - 0.00044 20.9 12.1 0.79 10.7 0.3 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger DUF4674 PF15719.5 KLO18397.1 - 0.017 15.2 0.8 0.043 13.8 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) zf-C2H2_6 PF13912.6 KLO18397.1 - 2.9 8.0 8.8 17 5.5 0.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger Vps53_N PF04100.12 KLO18398.1 - 1.2e-87 294.4 1.8 1.2e-87 294.4 1.8 1.6 2 0 0 2 2 2 1 Vps53-like, N-terminal VPS53_C PF16854.5 KLO18398.1 - 9.1e-06 25.7 5.7 0.00019 21.4 0.0 3.8 2 2 1 4 4 4 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps54_N PF10475.9 KLO18398.1 - 0.0016 17.8 6.6 0.0038 16.5 6.6 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KLO18398.1 - 0.0081 16.0 2.4 0.014 15.2 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Spc7 PF08317.11 KLO18398.1 - 0.014 14.3 12.0 0.031 13.2 12.0 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF812 PF05667.11 KLO18398.1 - 0.025 13.5 10.1 0.047 12.6 10.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SidE PF12252.8 KLO18398.1 - 0.14 9.7 11.2 0.079 10.5 0.2 2.1 2 0 0 2 2 2 0 Dot/Icm substrate protein DUF1664 PF07889.12 KLO18398.1 - 0.17 12.0 7.3 0.5 10.4 6.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Myb_DNA-bind_3 PF12776.7 KLO18398.1 - 0.23 12.5 1.1 2.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain NBD94 PF16830.5 KLO18398.1 - 0.35 11.3 9.5 0.19 12.1 4.7 2.5 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH DUF3450 PF11932.8 KLO18398.1 - 0.38 10.0 10.5 0.75 9.0 10.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Sec5 PF15469.6 KLO18398.1 - 0.69 9.7 8.3 0.38 10.5 5.7 1.9 2 0 0 2 2 2 0 Exocyst complex component Sec5 CorA PF01544.18 KLO18398.1 - 1 8.6 7.1 2.6 7.3 7.1 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 KLO18398.1 - 1.3 9.1 10.7 1.5 8.8 7.7 2.8 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 KLO18398.1 - 9.9 6.3 11.1 40 4.3 3.0 3.6 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 VSP PF03302.13 KLO18399.1 - 0.1 11.4 0.1 0.1 11.4 0.1 1.5 2 0 0 2 2 2 0 Giardia variant-specific surface protein Rax2 PF12768.7 KLO18399.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 KLO18399.1 - 0.16 11.4 0.6 0.34 10.4 0.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MtrF PF09472.10 KLO18399.1 - 0.41 10.1 1.2 0.98 8.9 1.2 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) AAA_5 PF07728.14 KLO18401.1 - 0.0035 17.4 0.1 0.055 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KLO18401.1 - 0.013 15.3 0.8 0.037 13.9 0.8 1.8 1 0 0 1 1 1 0 AAA lid domain Rpr2 PF04032.16 KLO18402.1 - 3.5e-20 72.1 0.3 9.3e-20 70.7 0.3 1.8 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_S5 PF00333.20 KLO18403.1 - 1.3e-28 98.8 0.6 1.3e-28 98.8 0.6 2.5 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KLO18403.1 - 3.8e-24 83.9 0.1 6e-24 83.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Abhydrolase_3 PF07859.13 KLO18404.1 - 7.2e-15 55.4 0.0 5.7e-14 52.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KLO18404.1 - 4.9e-09 35.6 0.0 4.2e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KLO18404.1 - 1.9e-05 23.7 0.0 2.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KLO18404.1 - 8.3e-05 22.1 0.0 0.01 15.3 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KLO18404.1 - 0.0099 15.2 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KLO18404.1 - 0.02 15.5 0.3 0.039 14.6 0.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1749 PF08538.10 KLO18404.1 - 0.16 11.1 0.0 1.5 7.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) ubiquitin PF00240.23 KLO18405.1 - 1.6e-15 56.6 1.1 1.1e-12 47.5 0.3 2.4 2 1 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 KLO18405.1 - 0.00012 21.8 0.2 0.00024 20.8 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KLO18405.1 - 0.0022 18.3 0.1 0.0046 17.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 KLO18405.1 - 0.018 15.5 0.1 0.045 14.2 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 KLO18405.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain RRN3 PF05327.11 KLO18405.1 - 6.4 5.2 8.1 8.3 4.8 8.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ODC_AZ PF02100.17 KLO18406.1 - 8.8e-13 48.2 0.0 1.2e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DUF1771 PF08590.10 KLO18407.1 - 6.4e-19 68.1 3.2 6.4e-19 68.1 3.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KLO18407.1 - 1.4e-11 44.6 0.2 3e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 Smr domain DnaJ PF00226.31 KLO18408.1 - 2.6e-09 37.1 0.1 3.9e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Phage-tail_3 PF13550.6 KLO18408.1 - 0.044 13.6 0.2 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Putative phage tail protein Amidohydro_2 PF04909.14 KLO18410.1 - 0.0084 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase PAD_N PF08526.10 KLO18410.1 - 0.053 13.9 0.1 0.096 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) N-terminal domain Cir_N PF10197.9 KLO18411.1 - 8.8e-06 25.8 0.3 8.8e-06 25.8 0.3 3.9 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Med25_VWA PF11265.8 KLO18412.1 - 5.4e-06 26.4 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Med25 PF11232.8 KLO18412.1 - 0.0021 18.1 0.2 0.0052 16.8 0.2 1.7 1 0 0 1 1 1 1 Mediator complex subunit 25 PTOV activation and synapsin 2 Lip_prot_lig_C PF10437.9 KLO18412.1 - 0.036 14.0 0.0 0.79 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Lactamase_B PF00753.27 KLO18414.1 - 6.9e-13 49.1 0.4 1.3e-12 48.2 0.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KLO18414.1 - 3.3e-06 26.8 0.0 5.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KLO18414.1 - 0.0086 15.5 0.2 0.016 14.7 0.0 1.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Presenilin PF01080.17 KLO18415.1 - 0.0091 14.8 3.2 0.014 14.2 3.2 1.3 1 0 0 1 1 1 1 Presenilin SPX PF03105.19 KLO18415.1 - 0.028 14.3 13.0 0.032 14.2 13.0 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 KLO18415.1 - 0.79 8.2 22.9 1.3 7.5 22.9 1.3 1 0 0 1 1 1 0 Macoilin family MAP65_ASE1 PF03999.12 KLO18415.1 - 1.6 7.4 14.3 1.8 7.2 14.3 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) E1-E2_ATPase PF00122.20 KLO18416.1 - 2.2e-30 105.5 0.3 7.3e-30 103.8 0.3 1.9 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 KLO18416.1 - 2.1e-23 82.8 0.4 4.3e-23 81.8 0.4 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 KLO18416.1 - 3.6e-18 66.6 0.0 1.7e-08 35.1 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KLO18416.1 - 8.7e-07 28.8 6.1 2.9e-06 27.1 6.1 1.9 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KLO18416.1 - 1.8e-06 27.9 0.0 3.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KLO18416.1 - 0.0095 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus V-SNARE_C PF12352.8 KLO18417.1 - 5.4e-16 58.6 1.5 7.1e-16 58.2 0.4 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KLO18417.1 - 1.4e-07 31.3 0.3 4.1e-07 29.8 0.0 1.9 2 1 0 2 2 2 1 Sec20 Med3 PF11593.8 KLO18417.1 - 0.013 14.7 0.4 0.017 14.4 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Plasmid_RAQPRD PF09686.10 KLO18417.1 - 0.023 14.9 2.6 0.065 13.4 1.5 2.3 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) PSI_PsaF PF02507.15 KLO18417.1 - 0.23 11.3 0.4 0.37 10.6 0.4 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III FliD_N PF02465.18 KLO18417.1 - 0.44 11.3 3.8 0.89 10.3 3.1 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus FAM72 PF14976.6 KLO18418.1 - 4.8e-17 62.5 1.8 2e-06 28.0 0.0 3.1 3 0 0 3 3 3 3 FAM72 protein Yippee-Mis18 PF03226.14 KLO18418.1 - 0.016 15.4 4.3 0.043 14.0 4.3 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nop25 PF09805.9 KLO18419.1 - 1.1e-16 61.6 19.0 1.1e-16 61.6 19.0 2.7 2 2 0 2 2 2 1 Nucleolar protein 12 (25kDa) Creatinase_N PF01321.18 KLO18419.1 - 0.033 14.8 0.1 0.098 13.3 0.1 1.9 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain MIF4G PF02854.19 KLO18421.1 - 1e-47 162.6 1.1 9.5e-29 100.5 0.0 4.0 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 KLO18421.1 - 9.8e-29 100.8 3.3 9.8e-29 100.8 3.3 3.5 3 1 0 3 3 3 1 Up-frameshift suppressor 2 MOR2-PAG1_C PF14225.6 KLO18421.1 - 0.075 12.9 1.1 1.5 8.7 0.1 2.8 3 0 0 3 3 3 0 Cell morphogenesis C-terminal DUF2408 PF10303.9 KLO18421.1 - 3.4 8.2 10.5 1 10.0 1.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Macoilin PF09726.9 KLO18422.1 - 0.087 11.4 15.2 0.13 10.8 15.2 1.1 1 0 0 1 1 1 0 Macoilin family FapA PF03961.13 KLO18422.1 - 0.088 11.4 3.4 0.14 10.7 3.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 KLO18422.1 - 0.38 8.6 7.4 0.71 7.7 7.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 KLO18422.1 - 0.64 10.2 23.2 0.24 11.6 16.4 2.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 KLO18422.1 - 4.8 4.6 18.1 7.6 3.9 18.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Glyco_transf_49 PF13896.6 KLO18423.1 - 0.00092 18.7 2.8 0.0018 17.7 0.2 2.1 1 1 1 2 2 2 1 Glycosyl-transferase for dystroglycan PhoLip_ATPase_C PF16212.5 KLO18423.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal p450 PF00067.22 KLO18424.1 - 1e-60 205.8 0.1 3.1e-60 204.2 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 Fe-ADH PF00465.19 KLO18425.1 - 4.7e-80 269.1 0.5 5.4e-80 268.9 0.5 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KLO18425.1 - 3.6e-15 56.3 0.1 4.7e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase UPF0261 PF06792.11 KLO18425.1 - 0.037 13.0 1.5 0.043 12.8 0.4 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0261) Peripla_BP_4 PF13407.6 KLO18425.1 - 0.051 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain DUF1967 PF09269.11 KLO18425.1 - 1.2 9.1 2.4 1.6 8.7 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) ADH_zinc_N PF00107.26 KLO18426.1 - 5.3e-33 113.8 0.2 7.4e-33 113.3 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KLO18426.1 - 1.3e-14 55.3 0.0 3.3e-14 54.1 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO18426.1 - 2.2e-07 30.7 0.0 1.6e-06 27.9 0.0 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KLO18426.1 - 0.0071 15.8 0.2 0.01 15.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 KLO18426.1 - 0.052 12.8 0.6 0.079 12.2 0.6 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KLO18426.1 - 0.055 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain RabGAP-TBC PF00566.18 KLO18427.1 - 8.4e-55 185.7 1.8 1.8e-54 184.7 0.6 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF641 PF04859.12 KLO18427.1 - 0.035 14.4 0.8 0.066 13.5 0.8 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.11 KLO18427.1 - 0.09 12.6 4.9 0.086 12.6 1.2 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 NACHT PF05729.12 KLO18429.1 - 2.9e-07 30.5 0.0 7e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO18429.1 - 7.7e-05 23.1 0.0 0.00026 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 KLO18429.1 - 0.004 17.0 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ABC_tran PF00005.27 KLO18429.1 - 0.0095 16.4 0.0 0.17 12.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 KLO18429.1 - 0.021 15.1 0.0 0.068 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain Torsin PF06309.11 KLO18429.1 - 0.046 13.8 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Torsin Rad17 PF03215.15 KLO18429.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 KLO18429.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KLO18429.1 - 0.084 13.4 0.0 0.28 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain RRM_2 PF04059.12 KLO18431.1 - 7.7e-31 106.2 0.4 9.7e-31 105.9 0.4 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KLO18431.1 - 0.0095 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ARS2 PF04959.13 KLO18431.1 - 0.3 11.4 3.6 0.48 10.8 3.6 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 STE3 PF02076.15 KLO18433.1 - 1.3e-59 201.8 14.6 1.5e-59 201.6 14.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor GidB PF02527.15 KLO18433.1 - 0.0031 16.9 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Aldo_ket_red PF00248.21 KLO18440.1 - 4.8e-65 219.7 0.0 6.5e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf_UBZ PF18439.1 KLO18441.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Tet_JBP PF12851.7 KLO18442.1 - 0.016 14.6 0.1 0.037 13.4 0.1 1.6 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily MULE PF10551.9 KLO18444.1 - 7.4e-10 39.1 0.0 3.2e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 KLO18444.1 - 0.026 14.2 1.0 0.059 13.1 1.0 1.6 1 0 0 1 1 1 0 SWIM zinc finger DUF724 PF05266.14 KLO18444.1 - 0.24 11.2 1.4 0.55 10.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Cauli_VI PF01693.16 KLO18445.1 - 0.1 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Caulimovirus viroplasmin MULE PF10551.9 KLO18447.1 - 5.2e-12 46.0 0.0 9.9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF5641 PF18701.1 KLO18448.1 - 0.1 12.7 3.6 0.23 11.6 3.6 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5641) NDUFB10 PF10249.9 KLO18452.1 - 0.061 13.8 1.6 0.2 12.2 0.3 2.0 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 CK2S PF15011.6 KLO18452.1 - 5 7.0 13.5 0.73 9.7 6.1 2.5 1 1 2 3 3 3 0 Casein Kinase 2 substrate STAG PF08514.11 KLO18457.1 - 0.13 12.2 0.9 0.23 11.4 0.9 1.4 1 0 0 1 1 1 0 STAG domain FAM220 PF15487.6 KLO18464.1 - 0.13 11.8 0.2 0.18 11.4 0.2 1.2 1 0 0 1 1 1 0 FAM220 family Antimicrobial11 PF08106.11 KLO18467.1 - 0.48 10.5 3.4 1.1 9.4 0.7 2.5 2 0 0 2 2 2 0 Formaecin family YrvL PF14184.6 KLO18476.1 - 0.032 14.3 0.1 0.066 13.3 0.0 1.5 2 0 0 2 2 2 0 Regulatory protein YrvL Jnk-SapK_ap_N PF09744.9 KLO18481.1 - 0.012 15.8 0.2 0.013 15.7 0.2 1.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 XkdW PF09636.10 KLO18481.1 - 0.028 14.5 0.5 0.033 14.3 0.5 1.2 1 0 0 1 1 1 0 XkdW protein HJURP_C PF12347.8 KLO18481.1 - 0.12 12.4 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat FUN14 PF04930.15 KLO18481.1 - 0.25 11.8 0.0 0.31 11.5 0.0 1.1 1 0 0 1 1 1 0 FUN14 family Zn_clus PF00172.18 KLO18484.1 - 8.9 6.5 14.6 17 5.7 14.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4407 PF14362.6 KLO18488.1 - 2 7.7 6.9 1.7 7.9 3.8 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Aldo_ket_red PF00248.21 KLO18489.1 - 1.2e-66 224.9 0.0 1.4e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Imm1 PF14430.6 KLO18489.1 - 0.075 13.7 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Immunity protein Imm1 F-box-like PF12937.7 KLO18493.1 - 0.00014 21.7 0.9 0.0016 18.3 0.1 3.2 4 1 1 5 5 5 1 F-box-like F-box-like PF12937.7 KLO18494.1 - 0.00063 19.6 0.1 0.0019 18.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like DUF3557 PF12078.8 KLO18494.1 - 0.0008 19.4 0.3 0.013 15.4 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3557) LRR_9 PF14580.6 KLO18494.1 - 0.035 13.6 0.3 0.11 11.9 0.1 1.9 2 0 0 2 2 2 0 Leucine-rich repeat F-box-like PF12937.7 KLO18495.1 - 8.8e-05 22.3 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like HTH_3 PF01381.22 KLO18495.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix LRR_4 PF12799.7 KLO18496.1 - 0.01 16.2 1.6 6.4 7.3 0.0 3.7 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO18496.1 - 0.031 14.2 0.2 0.082 12.8 0.2 1.8 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.6 KLO18496.1 - 0.05 13.4 1.0 8 6.3 0.2 3.0 2 0 0 2 2 2 0 Leucine rich repeat Methyltransf_25 PF13649.6 KLO18497.1 - 0.00014 22.5 0.1 0.0026 18.4 0.1 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO18497.1 - 0.012 16.3 0.0 0.034 14.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KLO18497.1 - 0.1 13.4 0.0 6 7.7 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.7 KLO18498.1 - 6.5e-05 22.7 0.3 0.00035 20.4 0.0 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KLO18498.1 - 7.6 7.1 6.9 13 6.4 0.6 4.1 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO18499.1 - 4.5e-08 32.8 0.0 1.3e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO18500.1 - 7.6e-09 35.3 0.5 6.7e-08 32.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO18501.1 - 2.2e-07 30.7 0.5 2.3e-06 27.4 0.2 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO18501.1 - 0.044 13.7 0.8 0.26 11.2 0.8 2.4 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.7 KLO18501.1 - 0.17 12.3 1.2 11 6.7 0.0 3.3 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO18502.1 - 3.7e-08 33.1 0.1 1.1e-07 31.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO18506.1 - 0.017 15.0 1.7 0.51 10.3 0.1 2.9 2 0 0 2 2 2 0 F-box-like ISP3_C PF18045.1 KLO18508.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 ISP3 C-terminal UvrD_C_2 PF13538.6 KLO18509.1 - 0.0029 17.4 0.1 0.016 15.0 0.1 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Myb_DNA-bind_6 PF13921.6 KLO18509.1 - 0.037 14.3 0.3 0.064 13.5 0.3 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain F-box PF00646.33 KLO18512.1 - 3.1e-05 23.7 1.7 0.00085 19.1 0.1 2.9 2 0 0 2 2 2 1 F-box domain Speriolin_C PF15059.6 KLO18512.1 - 0.026 14.7 0.1 0.084 13.0 0.0 1.9 1 1 0 1 1 1 0 Speriolin C-terminus F-box_4 PF15966.5 KLO18512.1 - 0.033 14.1 0.6 0.24 11.3 0.1 2.5 2 0 0 2 2 2 0 F-box F-box-like PF12937.7 KLO18512.1 - 0.12 12.3 0.4 11 6.0 0.1 2.8 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KLO18513.1 - 0.00021 21.1 0.8 0.00057 19.7 0.1 2.2 2 0 0 2 2 2 1 F-box domain PI3K_P85_iSH2 PF16454.5 KLO18513.1 - 0.14 11.8 0.3 0.3 10.7 0.3 1.5 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ArfGap PF01412.18 KLO18515.1 - 0.0049 16.9 1.9 0.043 13.9 0.3 2.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf F-box PF00646.33 KLO18515.1 - 0.013 15.4 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 F-box domain DSBA PF01323.20 KLO18516.1 - 1.6e-22 80.2 0.0 2e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain F-box PF00646.33 KLO18517.1 - 2.2e-06 27.4 0.1 4e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO18517.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 F-box-like zf-MYST PF17772.1 KLO18518.1 - 0.031 13.9 0.3 0.094 12.3 0.3 1.8 1 0 0 1 1 1 0 MYST family zinc finger domain F-box PF00646.33 KLO18519.1 - 8.3e-05 22.4 0.4 0.00021 21.1 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box PF00646.33 KLO18520.1 - 6.3e-06 25.9 0.1 2.5e-05 24.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KLO18520.1 - 0.045 13.6 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 F-box DUF4096 PF13340.6 KLO18520.1 - 0.76 10.0 2.8 19 5.5 0.0 3.5 4 0 0 4 4 4 0 Putative transposase of IS4/5 family (DUF4096) zf-C4_ClpX PF06689.13 KLO18521.1 - 0.0027 17.6 0.8 0.0064 16.4 0.8 1.7 1 0 0 1 1 1 1 ClpX C4-type zinc finger F-box PF00646.33 KLO18521.1 - 0.0059 16.5 0.1 0.042 13.8 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KLO18521.1 - 0.074 13.0 0.1 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 F-box-like Latarcin PF10279.9 KLO18521.1 - 2 8.9 4.8 0.39 11.1 0.2 2.3 3 1 0 3 3 3 0 Latarcin precursor ERAP1_C PF11838.8 KLO18524.1 - 6.2e-70 236.2 0.1 9.5e-70 235.6 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KLO18524.1 - 3e-69 232.9 0.3 6.1e-69 231.9 0.3 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KLO18524.1 - 1.3e-47 162.4 0.0 3e-47 161.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain MFS_1 PF07690.16 KLO18525.1 - 6.5e-33 114.1 31.7 8.3e-33 113.8 31.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KLO18525.1 - 3.5e-05 23.3 2.9 3.5e-05 23.3 2.9 2.6 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Peptidase_M20 PF01546.28 KLO18526.1 - 1.2e-09 38.2 0.3 2.3e-09 37.3 0.3 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KLO18526.1 - 2.6e-08 33.7 0.0 7.7e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain HECT PF00632.25 KLO18527.1 - 3.7e-94 315.7 0.0 4.5e-94 315.4 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KLO18527.1 - 5.4e-35 119.2 13.7 5.5e-13 48.8 1.3 3.5 3 0 0 3 3 3 3 WW domain DUF2654 PF10849.8 KLO18527.1 - 0.53 10.5 1.3 26 5.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) Sfi1 PF08457.10 KLO18528.1 - 3e-32 111.9 114.0 2.1e-14 53.0 38.1 4.2 1 1 3 4 4 4 4 Sfi1 spindle body protein CLTH PF10607.9 KLO18529.1 - 2e-20 73.2 0.0 4.4e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KLO18529.1 - 1.5e-06 28.2 0.7 2.8e-06 27.2 0.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KLO18529.1 - 0.00067 19.1 1.4 0.00074 19.0 0.1 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KLO18529.1 - 0.0031 17.8 1.3 0.0057 17.0 1.3 1.5 1 0 0 1 1 1 1 Ring finger domain Tropomyosin PF00261.20 KLO18529.1 - 0.015 14.7 0.4 0.024 14.0 0.4 1.3 1 0 0 1 1 1 0 Tropomyosin DHR10 PF18595.1 KLO18529.1 - 0.028 14.5 0.9 0.053 13.6 0.9 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain zf-C3HC4 PF00097.25 KLO18529.1 - 0.03 14.2 2.0 0.056 13.3 2.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KLO18529.1 - 0.039 13.8 2.6 0.085 12.7 2.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KLO18529.1 - 0.044 14.0 1.9 0.096 12.9 1.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KLO18529.1 - 0.056 13.4 1.3 0.12 12.4 1.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain NleF_casp_inhib PF16809.5 KLO18529.1 - 0.14 12.1 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 NleF caspase inhibitor zf-C3HC4_2 PF13923.6 KLO18529.1 - 0.69 9.8 3.1 1.3 8.9 3.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase_fungal PF17667.1 KLO18530.1 - 5e-51 173.7 0.1 4.5e-50 170.6 0.1 2.1 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KLO18530.1 - 7.8e-09 35.3 0.2 3.8e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KLO18530.1 - 0.011 15.1 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rpp20 PF12328.8 KLO18532.1 - 9.8e-07 28.8 0.0 1.6e-05 24.9 0.0 2.0 1 1 1 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KLO18532.1 - 0.00095 18.9 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Alba Biotin_lipoyl PF00364.22 KLO18533.1 - 2.2e-18 65.9 0.7 4.4e-18 64.9 0.7 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KLO18533.1 - 1.8e-07 31.4 0.0 4.7e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KLO18533.1 - 0.16 11.8 0.0 2.8 7.8 0.0 2.8 3 0 0 3 3 3 0 Biotin-lipoyl like Sterol-sensing PF12349.8 KLO18534.1 - 2.6e-36 124.8 6.3 6.5e-36 123.5 6.3 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KLO18534.1 - 2.3e-12 45.9 0.0 3.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Patched family Rad1 PF02144.16 KLO18535.1 - 8.7e-76 254.6 0.0 9.9e-76 254.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_N PF00705.18 KLO18535.1 - 0.0016 18.2 0.0 0.62 9.8 0.0 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, N-terminal domain Lysine_decarbox PF03641.14 KLO18536.1 - 3.1e-34 117.9 0.0 4.2e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KLO18536.1 - 1.5e-08 34.4 0.1 2.6e-08 33.6 0.1 1.4 1 1 0 1 1 1 1 SLOG cluster4 family Peptidase_M41 PF01434.18 KLO18537.1 - 2e-55 187.6 2.0 3.8e-55 186.7 2.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KLO18537.1 - 1.3e-41 142.1 0.1 3.3e-41 140.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KLO18537.1 - 5e-10 39.0 0.0 1.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KLO18537.1 - 0.00012 22.5 2.3 0.017 15.5 0.2 3.3 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 KLO18537.1 - 0.00049 19.4 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KLO18537.1 - 0.00061 19.6 0.0 0.0025 17.6 0.0 2.1 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KLO18537.1 - 0.00086 19.6 0.8 0.02 15.2 0.8 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KLO18537.1 - 0.0019 18.2 0.1 0.0076 16.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KLO18537.1 - 0.0041 17.3 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KLO18537.1 - 0.005 17.0 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KLO18537.1 - 0.0096 15.1 0.0 0.027 13.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 KLO18537.1 - 0.013 15.4 0.1 0.22 11.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 KLO18537.1 - 0.018 15.3 0.0 0.049 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KLO18537.1 - 0.022 15.3 0.0 0.058 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KLO18537.1 - 0.038 13.4 0.5 0.038 13.4 0.5 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KLO18537.1 - 0.054 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KLO18537.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 KLO18537.1 - 0.064 12.8 4.0 1.2 8.7 0.6 2.8 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KLO18537.1 - 0.12 11.6 5.0 0.065 12.5 0.5 2.9 4 1 0 4 4 4 0 Zeta toxin ATPase PF06745.13 KLO18537.1 - 0.14 11.5 0.6 0.47 9.8 0.5 1.8 1 1 0 1 1 1 0 KaiC AAA_19 PF13245.6 KLO18537.1 - 0.41 11.0 3.2 2.8 8.2 0.5 2.6 2 0 0 2 2 2 0 AAA domain Peptidase_M50B PF13398.6 KLO18537.1 - 0.52 9.9 3.7 0.19 11.3 0.1 1.9 2 0 0 2 2 2 0 Peptidase M50B-like SpoIIE PF07228.12 KLO18538.1 - 6.2e-12 45.8 0.0 9.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KLO18538.1 - 0.0011 18.6 0.1 0.0024 17.5 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C DNA_pol3_gamma3 PF12169.8 KLO18538.1 - 0.044 13.7 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III WHIM1 PF15612.6 KLO18538.1 - 0.21 11.2 0.1 0.41 10.3 0.1 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Peptidase_M49 PF03571.15 KLO18539.1 - 6.4e-226 751.0 0.0 7.5e-226 750.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 LIM PF00412.22 KLO18540.1 - 1.1e-14 54.4 27.3 1.1e-10 41.5 11.1 4.3 5 1 0 5 5 5 2 LIM domain Glyoxal_oxid_N PF07250.11 KLO18541.1 - 3e-33 115.0 0.1 3.4e-32 111.5 0.0 2.4 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KLO18541.1 - 4.7e-24 84.5 0.2 8.7e-24 83.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Lipoprotein_15 PF03640.15 KLO18541.1 - 0.068 12.7 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Secreted repeat of unknown function KH_1 PF00013.29 KLO18542.1 - 0.0065 16.3 0.5 0.015 15.1 0.5 1.6 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 KLO18542.1 - 0.016 15.3 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Krr1 KH1 domain DUF3835 PF12927.7 KLO18543.1 - 0.00038 21.2 0.0 0.00038 21.2 0.0 4.4 3 2 1 4 4 4 2 Domain of unknown function (DUF3835) SLY PF12485.8 KLO18543.1 - 2.5 8.8 14.2 0.048 14.4 6.5 2.1 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein Fungal_trans PF04082.18 KLO18544.1 - 9.6e-23 80.6 0.0 5.4e-22 78.1 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain SUIM_assoc PF16619.5 KLO18544.1 - 0.0082 16.2 0.9 0.0082 16.2 0.9 2.5 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Bac_export_2 PF01312.19 KLO18545.1 - 0.16 11.2 6.3 0.092 11.9 4.3 1.6 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family DHHC PF01529.20 KLO18546.1 - 1.2e-33 116.0 9.0 2.1e-33 115.3 9.0 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase UQ_con PF00179.26 KLO18547.1 - 1e-47 161.3 0.0 1.2e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KLO18547.1 - 0.00036 20.2 0.0 0.00044 20.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KLO18547.1 - 0.019 15.2 0.2 0.032 14.5 0.2 1.5 1 1 0 1 1 1 0 RWD domain CDH-cyt PF16010.5 KLO18548.1 - 5.2e-54 182.7 1.4 8.2e-54 182.1 1.4 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase CBM_1 PF00734.18 KLO18548.1 - 1.9e-10 40.5 15.6 3.1e-10 39.8 13.4 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain DOMON PF03351.17 KLO18548.1 - 0.0038 17.5 0.3 0.008 16.4 0.3 1.5 1 0 0 1 1 1 1 DOMON domain Glucan_synthase PF02364.15 KLO18549.1 - 0 1298.1 0.0 0 1297.6 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KLO18549.1 - 9.5e-39 132.7 0.5 2.7e-38 131.2 0.5 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Proteasome PF00227.26 KLO18550.1 - 9.5e-49 165.5 0.1 1.1e-48 165.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit SnoaL_2 PF12680.7 KLO18551.1 - 0.074 13.7 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain ComX PF05952.12 KLO18551.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacillus competence pheromone ComX adh_short_C2 PF13561.6 KLO18552.1 - 1.4e-56 191.7 0.0 1.8e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO18552.1 - 8.5e-41 139.6 0.4 1e-40 139.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO18552.1 - 2.9e-14 53.4 0.2 4.3e-14 52.8 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO18552.1 - 0.067 12.6 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2OG-FeII_Oxy_2 PF13532.6 KLO18553.1 - 2.1e-34 119.4 0.0 7.3e-33 114.4 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Tox-GHH PF15636.6 KLO18553.1 - 0.12 12.4 0.4 0.29 11.1 0.4 1.6 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Cmc1 PF08583.10 KLO18554.1 - 1.1e-11 44.6 3.7 1.3e-11 44.3 3.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_14kD PF02271.16 KLO18555.1 - 1.2e-39 134.3 2.4 1.4e-39 134.1 2.4 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit NDK PF00334.19 KLO18556.1 - 3.7e-55 185.6 0.0 4.3e-55 185.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 KLO18556.1 - 0.015 15.8 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Cytochrom_B561 PF03188.16 KLO18557.1 - 8.8e-12 45.3 2.7 8.8e-12 45.3 2.7 2.1 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 KLO18557.1 - 1e-10 41.6 3.2 1.2e-09 38.1 3.2 2.3 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KLO18557.1 - 5.6e-06 26.6 0.1 1.1e-05 25.7 0.1 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 KLO18557.1 - 0.0026 17.5 5.6 0.21 11.4 5.3 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF2427) DUF2306 PF10067.9 KLO18557.1 - 0.0095 16.1 0.9 0.03 14.5 0.9 1.9 1 1 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF4079 PF13301.6 KLO18557.1 - 0.1 12.8 1.3 3.9 7.6 2.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF420 PF04238.12 KLO18557.1 - 2.3 8.5 11.1 0.38 11.0 4.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF420) LETM1 PF07766.13 KLO18558.1 - 6.1e-104 347.1 1.0 6.1e-104 347.1 1.0 2.1 2 0 0 2 2 2 1 LETM1-like protein EF-hand_8 PF13833.6 KLO18558.1 - 0.00078 19.2 0.1 0.0045 16.8 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 KLO18558.1 - 0.002 18.6 9.3 0.016 15.7 0.0 4.8 5 1 0 5 5 5 1 EF-hand domain pair EF-hand_1 PF00036.32 KLO18558.1 - 0.0025 17.2 0.0 0.19 11.4 0.0 3.2 3 0 0 3 3 3 1 EF hand SAP PF02037.27 KLO18558.1 - 0.0044 16.7 0.0 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 SAP domain EF-hand_6 PF13405.6 KLO18558.1 - 0.0049 16.7 0.1 9.2 6.5 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KLO18558.1 - 0.024 14.1 0.0 0.8 9.3 0.0 2.6 2 0 0 2 2 2 0 EF hand ALMT PF11744.8 KLO18558.1 - 1.4 7.7 12.2 0.67 8.7 8.4 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter Gpr1_Fun34_YaaH PF01184.19 KLO18559.1 - 2.1e-32 112.4 20.5 2.6e-32 112.1 20.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family PIN_4 PF13638.6 KLO18560.1 - 4.5e-22 78.7 0.2 9.9e-22 77.6 0.2 1.6 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.9 KLO18560.1 - 7.6e-07 28.9 0.0 1.3e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain Robl_LC7 PF03259.17 KLO18560.1 - 0.016 14.9 0.7 0.74 9.6 0.1 2.7 2 0 0 2 2 2 0 Roadblock/LC7 domain PTCB-BRCT PF12738.7 KLO18561.1 - 6.1e-32 109.4 0.7 1.9e-10 40.6 0.1 3.9 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KLO18561.1 - 1e-24 86.7 0.2 2.7e-08 34.1 0.0 4.1 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KLO18561.1 - 4.1e-14 52.8 0.4 0.00034 21.0 0.0 4.5 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KLO18561.1 - 8.7e-06 25.9 2.5 0.11 12.8 0.2 3.1 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KLO18561.1 - 0.0009 19.3 1.8 0.25 11.4 0.0 3.7 5 0 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain Ribosomal_L30 PF00327.20 KLO18562.1 - 1.8e-10 40.5 0.0 2.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e PHC2_SAM_assoc PF16616.5 KLO18562.1 - 1.1 10.2 10.4 0.043 14.6 4.8 1.6 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Transcrip_reg PF01709.20 KLO18563.1 - 9.3e-64 215.1 0.0 1.1e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator WD40 PF00400.32 KLO18564.1 - 1.6e-22 79.4 16.6 6.9e-10 39.4 0.0 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO18564.1 - 2e-06 28.0 0.1 0.01 16.1 0.0 3.9 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO18564.1 - 0.011 14.7 0.1 0.099 11.6 0.0 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ATPase_2 PF01637.18 KLO18565.1 - 3.8e-13 49.9 0.0 3.5e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KLO18565.1 - 2.1e-06 28.2 0.2 1.7e-05 25.3 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO18565.1 - 0.0013 19.1 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KLO18565.1 - 0.005 17.3 0.0 2.4 8.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KLO18565.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 KLO18565.1 - 0.13 12.5 0.0 0.93 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain 4HBT PF03061.22 KLO18566.1 - 1.3e-11 44.7 0.0 2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KLO18566.1 - 0.00015 22.2 0.0 0.00018 21.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KLO18566.1 - 0.00034 20.0 0.7 0.00085 18.7 0.8 1.5 2 0 0 2 2 2 1 Acyl-ACP thioesterase E1_4HB PF16191.5 KLO18566.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Acyltransferase PF01553.21 KLO18568.1 - 2e-11 43.7 0.0 8.4e-05 22.2 0.0 2.6 3 0 0 3 3 3 2 Acyltransferase zf-C2H2_3 PF13878.6 KLO18569.1 - 0.18 11.7 0.7 0.45 10.4 0.7 1.8 1 1 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Peptidase_M24 PF00557.24 KLO18570.1 - 2.5e-52 177.6 0.0 3.2e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KLO18570.1 - 2.7e-16 59.6 10.0 5.1e-16 58.7 10.0 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KLO18570.1 - 0.48 10.6 5.1 0.99 9.6 5.1 1.5 1 0 0 1 1 1 0 MYND finger NYN PF01936.18 KLO18571.1 - 2.3e-26 93.0 0.0 4.7e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 NYN domain Peptidase_M24 PF00557.24 KLO18572.1 - 2.8e-50 170.9 0.1 3.6e-50 170.6 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KLO18572.1 - 2.7e-19 69.2 8.3 4.7e-19 68.4 8.3 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KLO18572.1 - 0.00053 20.0 3.4 0.0011 19.0 3.4 1.5 1 0 0 1 1 1 1 MYND finger FGase PF05013.12 KLO18572.1 - 0.15 12.2 0.0 0.46 10.7 0.0 1.8 2 0 0 2 2 2 0 N-formylglutamate amidohydrolase F-box-like PF12937.7 KLO18573.1 - 2.6e-08 33.6 1.7 7e-08 32.3 0.0 2.4 2 0 0 2 2 2 1 F-box-like NYN PF01936.18 KLO18574.1 - 3.7e-25 89.1 0.0 4.4e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 NYN domain Peptidase_S37 PF05576.11 KLO18574.1 - 0.085 11.5 0.0 0.097 11.3 0.0 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 Sulfate_transp PF00916.20 KLO18575.1 - 1.9e-117 392.3 12.9 2.3e-117 392.0 12.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KLO18575.1 - 5e-11 42.3 0.0 1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KLO18575.1 - 0.033 14.5 0.1 0.079 13.3 0.1 1.6 1 0 0 1 1 1 0 STAS domain MFS_MOT1 PF16983.5 KLO18575.1 - 0.22 11.9 14.5 0.068 13.6 3.4 2.9 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily Peptidase_M1 PF01433.20 KLO18576.1 - 1.9e-64 217.2 1.8 3.2e-64 216.5 1.8 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KLO18576.1 - 1.7e-55 188.8 0.0 3e-55 188.0 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KLO18576.1 - 1.2e-44 152.8 0.0 2.8e-44 151.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain NAC PF01849.18 KLO18577.1 - 2.9e-20 72.0 0.0 5.4e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 NAC domain Glyco_tran_28_C PF04101.16 KLO18578.1 - 1.5e-27 96.6 0.0 1.7e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain CLASP_N PF12348.8 KLO18579.1 - 9.1e-28 97.4 0.0 6.8e-10 38.9 0.1 6.0 6 0 0 6 6 6 4 CLASP N terminal HEAT PF02985.22 KLO18579.1 - 2.4e-13 49.1 16.8 0.019 15.2 0.1 11.8 12 0 0 12 12 12 2 HEAT repeat Cnd1 PF12717.7 KLO18579.1 - 7.4e-11 42.4 0.2 0.37 10.8 0.0 7.2 7 1 0 7 7 7 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KLO18579.1 - 1.5e-09 38.1 20.1 1.9 8.9 0.0 10.4 7 4 5 12 12 12 4 HEAT repeats TAN PF11640.8 KLO18579.1 - 0.00096 19.3 1.5 3.1 7.9 0.0 4.7 4 0 0 4 4 4 1 Telomere-length maintenance and DNA damage repair Adaptin_N PF01602.20 KLO18579.1 - 0.0013 17.4 0.1 2.2 6.7 0.0 4.4 5 0 0 5 5 5 1 Adaptin N terminal region MMS19_N PF14500.6 KLO18579.1 - 0.0032 17.1 1.4 3.8 7.0 0.0 4.9 4 1 1 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II Nipped-B_C PF12830.7 KLO18579.1 - 0.011 15.7 0.0 17 5.3 0.0 3.6 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KLO18579.1 - 0.029 14.7 5.3 2.3 8.6 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DCB PF16213.5 KLO18579.1 - 0.039 13.6 0.0 18 5.0 0.0 3.7 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 HEAT_EZ PF13513.6 KLO18579.1 - 0.34 11.5 9.5 43 4.8 0.0 7.1 6 1 1 7 7 7 0 HEAT-like repeat IF-2B PF01008.17 KLO18581.1 - 5.2e-57 193.2 0.0 6.1e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cyclin_N PF00134.23 KLO18582.1 - 3.6e-16 59.1 0.1 5e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KLO18582.1 - 1.4e-06 28.2 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor TFIIB repeat GARP PF16731.5 KLO18582.1 - 0.0038 16.9 1.2 0.0057 16.4 1.2 1.3 1 0 0 1 1 1 1 Glutamic acid/alanine-rich protein of Trypanosoma GDNF PF02351.16 KLO18582.1 - 0.074 14.0 0.5 0.11 13.4 0.5 1.3 1 0 0 1 1 1 0 GDNF/GAS1 domain RWD PF05773.22 KLO18583.1 - 4.3e-20 72.1 1.0 1e-19 71.0 1.0 1.6 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KLO18583.1 - 5e-06 26.9 17.0 7.2e-06 26.4 13.9 2.8 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 Spc7_C2 PF15577.6 KLO18583.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Spc7_C2 Ribosomal_S21 PF01165.20 KLO18584.1 - 1.7e-13 50.0 4.2 1.7e-13 50.0 4.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S21 DUF4211 PF13926.6 KLO18584.1 - 0.015 15.4 0.2 0.015 15.4 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) Rab3-GTPase_cat PF13890.6 KLO18586.1 - 0.1 12.2 0.0 2 8.0 0.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein catalytic subunit Abhydrolase_1 PF00561.20 KLO18587.1 - 2.1e-08 34.1 0.0 6.6e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO18587.1 - 0.00061 19.1 0.0 0.016 14.4 0.0 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 SET PF00856.28 KLO18588.1 - 1.9e-05 25.1 0.0 5.9e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 SET domain Arm PF00514.23 KLO18589.1 - 4.5e-10 39.2 18.3 0.00041 20.3 0.2 7.8 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KLO18589.1 - 1.7e-08 34.0 28.2 0.0096 16.1 0.1 10.0 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.6 KLO18589.1 - 1.8e-06 28.3 10.0 0.19 12.3 0.0 7.0 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 KLO18589.1 - 6.6e-06 26.4 17.0 0.52 10.7 0.0 7.8 5 3 1 6 6 6 1 HEAT repeats V-ATPase_H_C PF11698.8 KLO18589.1 - 9.2e-06 25.8 6.2 0.95 9.6 0.1 4.2 4 1 0 4 4 4 3 V-ATPase subunit H DUF3361 PF11841.8 KLO18589.1 - 1.9e-05 24.6 4.0 5.5e-05 23.1 0.9 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3361) PUL PF08324.11 KLO18589.1 - 6.1e-05 22.4 1.3 0.19 11.0 0.3 3.0 2 1 1 3 3 3 2 PUL domain V-ATPase_H_N PF03224.14 KLO18589.1 - 0.0016 17.8 1.6 0.0057 16.0 0.1 2.4 2 1 1 3 3 3 1 V-ATPase subunit H RasGEF_N_2 PF14663.6 KLO18589.1 - 0.012 16.0 0.2 0.28 11.6 0.1 3.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KLO18589.1 - 0.017 15.4 0.1 3.2 8.1 0.0 3.4 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 IFRD PF05004.13 KLO18589.1 - 0.017 14.2 9.4 0.021 13.9 2.2 3.5 3 2 1 4 4 4 0 Interferon-related developmental regulator (IFRD) IBN_N PF03810.19 KLO18589.1 - 0.019 14.9 7.7 5 7.1 0.1 5.0 5 2 1 6 6 6 0 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KLO18589.1 - 0.022 15.3 1.7 3.4 8.3 0.1 3.6 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region CoaE PF01121.20 KLO18590.1 - 2.3e-65 219.6 0.0 2.7e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KLO18590.1 - 0.00041 20.9 0.3 0.0042 17.6 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KLO18590.1 - 0.0028 17.9 0.0 0.0062 16.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KLO18590.1 - 0.015 15.4 0.3 0.14 12.3 0.3 2.4 1 1 0 1 1 1 0 AAA domain HSF_DNA-bind PF00447.17 KLO18591.1 - 1.7e-34 118.3 1.0 2.9e-34 117.6 1.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 KLO18591.1 - 0.086 13.3 0.1 0.25 11.8 0.1 1.8 1 0 0 1 1 1 0 Ets-domain Arrestin_C PF02752.22 KLO18592.1 - 2.6e-10 40.9 0.0 1.7e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KLO18592.1 - 4e-05 23.4 0.0 0.0009 19.0 0.0 2.2 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 KLO18592.1 - 0.0027 17.8 0.0 0.029 14.4 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF382 PF04037.13 KLO18594.1 - 6.2e-60 200.9 0.5 6.2e-60 200.9 0.5 2.5 3 1 1 4 4 4 1 Domain of unknown function (DUF382) PSP PF04046.16 KLO18594.1 - 2.4e-17 62.5 4.3 4.9e-17 61.5 4.3 1.6 1 0 0 1 1 1 1 PSP FAM83 PF07894.12 KLO18594.1 - 0.14 11.7 0.1 0.14 11.7 0.1 1.7 2 0 0 2 2 2 0 FAM83 A-H MitMem_reg PF13012.6 KLO18596.1 - 9.8e-36 122.6 0.5 1.5e-35 122.0 0.5 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KLO18596.1 - 2.1e-30 105.1 0.0 4.5e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Connexin PF00029.19 KLO18596.1 - 0.087 12.6 0.3 0.13 12.0 0.3 1.2 1 0 0 1 1 1 0 Connexin CNH PF00780.22 KLO18597.1 - 1.6e-24 87.0 0.0 2.5e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KLO18597.1 - 3.2e-08 34.0 0.1 4.7e-05 23.7 0.0 2.8 3 0 0 3 3 3 2 RhoGEF domain PH_5 PF15405.6 KLO18597.1 - 0.036 14.2 0.0 0.53 10.4 0.0 2.4 1 1 1 2 2 2 0 Pleckstrin homology domain Pkinase_Tyr PF07714.17 KLO18597.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein tyrosine kinase PMT PF02366.18 KLO18599.1 - 3e-80 269.3 16.7 3e-80 269.3 16.7 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KLO18599.1 - 6.2e-61 205.5 18.1 6.2e-61 205.5 18.1 1.9 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KLO18599.1 - 1.3e-28 100.2 0.3 2e-28 99.5 0.3 1.2 1 0 0 1 1 1 1 MIR domain Pkr1 PF08636.10 KLO18599.1 - 1.4 9.1 7.8 1.2 9.3 1.5 3.0 2 0 0 2 2 2 0 ER protein Pkr1 Fibrillarin PF01269.17 KLO18600.1 - 3.6e-104 346.8 0.0 4.3e-104 346.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KLO18600.1 - 0.00012 21.8 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 KLO18600.1 - 0.043 13.5 0.0 0.093 12.4 0.0 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KLO18600.1 - 0.16 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase DnaJ PF00226.31 KLO18601.1 - 4.7e-21 74.7 1.4 4.7e-21 74.7 1.4 2.7 3 0 0 3 3 3 1 DnaJ domain Ribosomal_S21e PF01249.18 KLO18605.1 - 8.9e-36 121.9 0.0 1e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e adh_short PF00106.25 KLO18606.1 - 1.2e-55 188.0 1.3 1.5e-55 187.7 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO18606.1 - 4.3e-36 124.6 0.6 5.3e-36 124.3 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO18606.1 - 4.1e-16 59.4 0.3 5e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO18606.1 - 3.4e-05 23.4 0.5 6.6e-05 22.5 0.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KLO18606.1 - 0.00046 19.4 0.2 0.00063 19.0 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KLO18606.1 - 0.0008 18.9 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KLO18606.1 - 0.0038 17.1 0.7 0.0049 16.8 0.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KLO18606.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KLO18606.1 - 0.021 14.1 0.1 0.056 12.8 0.1 1.7 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KLO18606.1 - 0.035 14.0 0.8 0.045 13.6 0.2 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KLO18606.1 - 0.1 12.2 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 KLO18606.1 - 0.14 11.7 1.2 0.21 11.1 1.2 1.3 1 0 0 1 1 1 0 NmrA-like family Antimicrobial10 PF08105.11 KLO18608.1 - 3.9 7.6 6.1 28 4.9 0.1 2.8 2 1 0 2 2 2 0 Metchnikowin family adh_short_C2 PF13561.6 KLO18612.1 - 4.7e-23 82.0 0.0 6.6e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO18612.1 - 5e-17 62.0 0.0 8.4e-17 61.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.25 KLO18614.1 - 3.1e-22 79.0 0.0 4.5e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO18614.1 - 1.2e-11 44.7 0.0 1.5e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO18614.1 - 0.00083 19.3 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO18614.1 - 0.13 11.7 0.0 14 5.0 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 KLO18615.1 - 3.9e-91 305.8 0.0 5.1e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KLO18615.1 - 9.9e-12 45.7 0.7 2.2e-11 44.5 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KLO18616.1 - 1e-88 297.8 0.0 1.3e-88 297.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KLO18616.1 - 7.3e-12 46.1 0.3 1.6e-11 45.0 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_transf_22 PF03901.17 KLO18617.1 - 4.9e-95 319.2 26.8 6.1e-95 318.9 26.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Amidohydro_1 PF01979.20 KLO18618.1 - 4.8e-68 230.0 0.0 8.8e-68 229.1 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KLO18618.1 - 6.3e-13 49.0 0.0 4e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Lipase_3 PF01764.25 KLO18619.1 - 2.1e-07 30.9 0.0 2.4e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KLO18619.1 - 0.0015 19.2 0.1 0.0024 18.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 KLO18619.1 - 0.014 15.4 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 KLO18619.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO18619.1 - 0.032 13.5 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KLO18619.1 - 0.083 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase PF00151.19 KLO18619.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipase MARVEL PF01284.23 KLO18620.1 - 0.001 19.1 6.7 0.013 15.5 3.6 2.2 2 0 0 2 2 2 2 Membrane-associating domain HgmA PF04209.13 KLO18621.1 - 0.004 15.9 0.0 0.0058 15.4 0.0 1.2 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase CTP_transf_like PF01467.26 KLO18622.1 - 3e-08 34.0 0.0 6.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KLO18622.1 - 0.04 13.8 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase mRNA_cap_enzyme PF01331.19 KLO18624.1 - 4.2e-52 176.8 0.1 5.6e-52 176.4 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KLO18624.1 - 8.2e-31 106.8 0.0 1.4e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KLO18624.1 - 3.3e-08 33.4 0.0 0.00069 19.3 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KLO18624.1 - 0.00037 20.9 0.0 0.0007 19.9 0.0 1.5 2 0 0 2 2 2 1 RNA ligase GSG-1 PF07803.11 KLO18624.1 - 0.19 11.7 0.1 0.34 10.9 0.1 1.3 1 0 0 1 1 1 0 GSG1-like protein CAP_N PF01213.19 KLO18624.1 - 0.4 10.1 4.4 0.57 9.6 4.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Skp1 PF01466.19 KLO18625.1 - 2.9e-28 97.7 0.8 5.9e-28 96.7 0.8 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KLO18625.1 - 3.1e-27 94.5 1.8 4e-27 94.2 0.2 2.0 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain BTB PF00651.31 KLO18625.1 - 0.0052 17.0 0.0 0.13 12.5 0.0 2.2 1 1 0 1 1 1 1 BTB/POZ domain CTP_transf_like PF01467.26 KLO18625.1 - 0.1 12.8 1.5 1 9.6 0.1 2.0 1 1 1 2 2 2 0 Cytidylyltransferase-like Ribosomal_L27 PF01016.19 KLO18626.1 - 7.8e-35 118.8 1.0 1.1e-34 118.3 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein DUF5568 PF17724.1 KLO18626.1 - 0.079 12.8 0.3 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5568) DEAD PF00270.29 KLO18627.1 - 5.9e-40 136.9 0.0 1e-39 136.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KLO18627.1 - 8.6e-23 80.3 0.8 1.5e-22 79.5 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KLO18627.1 - 3.8e-21 75.5 0.0 9.1e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO18627.1 - 8.7e-07 29.1 0.4 4e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KLO18627.1 - 0.041 14.2 0.3 0.36 11.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain DUF3074 PF11274.8 KLO18628.1 - 5.3e-42 143.9 0.2 8e-42 143.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) AAA PF00004.29 KLO18629.1 - 2.3e-44 151.0 0.1 7.3e-44 149.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KLO18629.1 - 2.3e-09 37.0 0.2 1.9e-08 34.1 0.0 2.5 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KLO18629.1 - 6.7e-09 35.9 0.1 1.9e-08 34.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KLO18629.1 - 5.7e-08 33.3 0.8 2.4e-05 24.8 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KLO18629.1 - 1e-07 32.2 0.1 3.4e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KLO18629.1 - 5.7e-06 25.7 0.0 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KLO18629.1 - 0.00011 22.8 0.1 0.0022 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KLO18629.1 - 0.00015 21.5 0.0 0.00035 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 KLO18629.1 - 0.00026 21.0 0.1 0.0014 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KLO18629.1 - 0.00043 20.6 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KLO18629.1 - 0.00055 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KLO18629.1 - 0.0007 19.6 0.0 0.0072 16.3 0.0 2.3 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KLO18629.1 - 0.00085 19.3 0.0 0.008 16.1 0.0 2.5 3 0 0 3 3 2 1 NTPase TIP49 PF06068.13 KLO18629.1 - 0.00087 18.6 0.0 0.0018 17.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 KLO18629.1 - 0.00089 19.6 0.0 0.0052 17.2 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 KLO18629.1 - 0.001 19.4 5.5 0.012 15.9 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_7 PF12775.7 KLO18629.1 - 0.0027 17.3 0.1 0.02 14.4 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 KLO18629.1 - 0.0032 17.2 0.3 0.0086 15.8 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KLO18629.1 - 0.0078 16.4 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KLO18629.1 - 0.0084 15.5 0.1 0.019 14.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KLO18629.1 - 0.0085 15.5 0.0 0.59 9.5 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 KLO18629.1 - 0.0093 15.7 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KLO18629.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KLO18629.1 - 0.011 15.7 0.1 0.078 12.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KLO18629.1 - 0.011 15.3 0.4 0.048 13.2 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 KLO18629.1 - 0.024 14.3 0.1 0.056 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KLO18629.1 - 0.027 14.4 2.1 0.49 10.3 0.1 3.1 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KLO18629.1 - 0.033 14.0 0.3 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KLO18629.1 - 0.043 14.1 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 KLO18629.1 - 0.066 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase Bac_DnaA PF00308.18 KLO18629.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.27 KLO18629.1 - 0.081 13.4 0.1 0.82 10.2 0.0 2.5 3 0 0 3 3 2 0 ABC transporter Sigma54_activat PF00158.26 KLO18629.1 - 0.095 12.4 0.2 1.2 8.8 0.0 2.6 3 1 0 3 3 2 0 Sigma-54 interaction domain ATPase PF06745.13 KLO18629.1 - 0.1 12.0 1.0 0.48 9.7 0.0 2.4 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.17 KLO18629.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DnaB_C PF03796.15 KLO18629.1 - 0.16 11.2 2.1 6.3 6.1 0.4 2.8 2 1 1 3 3 3 0 DnaB-like helicase C terminal domain AAA_23 PF13476.6 KLO18629.1 - 1.7 9.1 5.3 5 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Gln-synt_C PF00120.24 KLO18630.1 - 8.3e-75 251.9 0.0 3.8e-74 249.8 0.0 1.8 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain P5CR_dimer PF14748.6 KLO18631.1 - 2.8e-38 130.3 2.5 6.1e-38 129.2 2.5 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KLO18631.1 - 7.4e-11 42.5 0.0 8.7e-08 32.6 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Peptidase_M16_M PF16187.5 KLO18632.1 - 4e-54 183.8 4.9 4.2e-33 114.9 0.2 3.3 2 1 1 3 3 3 3 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KLO18632.1 - 4.7e-37 127.3 0.2 2.1e-36 125.1 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KLO18632.1 - 3.7e-20 72.7 0.2 5.6e-11 42.8 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Methyltransf_25 PF13649.6 KLO18633.1 - 1.7e-08 35.1 0.0 3.9e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO18633.1 - 2.7e-08 34.3 0.0 5.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO18633.1 - 0.00048 20.0 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO18633.1 - 0.0015 18.3 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO18633.1 - 0.046 14.5 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Hydrophobin PF01185.18 KLO18635.1 - 1.8e-07 31.7 4.0 2.6e-07 31.2 4.0 1.3 1 0 0 1 1 1 1 Fungal hydrophobin TRAF_BIRC3_bd PF16673.5 KLO18638.1 - 2.4 8.0 9.2 0.13 12.1 1.9 2.7 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain HOOK PF05622.12 KLO18638.1 - 3.1 5.8 39.9 18 3.3 39.4 2.0 1 1 0 1 1 1 0 HOOK protein HSP90 PF00183.18 KLO18639.1 - 8e-232 770.7 31.9 9.9e-232 770.4 31.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KLO18639.1 - 5e-15 56.0 0.0 1e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KLO18639.1 - 3.3e-09 36.7 0.1 3.3e-09 36.7 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 KLO18639.1 - 0.12 12.3 0.2 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN Peptidase_C37 PF05416.12 KLO18639.1 - 1.7 7.0 9.1 1.8 7.0 0.1 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Aminotran_5 PF00266.19 KLO18641.1 - 1.5e-29 103.1 0.0 1e-28 100.4 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Peptidase_C48 PF02902.19 KLO18644.1 - 0.0015 18.4 0.2 0.0047 16.8 0.0 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain CD99L2 PF12301.8 KLO18644.1 - 0.71 10.2 10.1 0.17 12.2 0.2 3.2 4 0 0 4 4 4 0 CD99 antigen like protein 2 GIDA PF01134.22 KLO18646.1 - 1.2e-147 492.1 0.0 1.6e-147 491.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KLO18646.1 - 5.5e-65 219.5 0.0 8.5e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 KLO18646.1 - 3.1e-05 23.4 1.5 0.00053 19.3 0.9 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KLO18646.1 - 8.3e-05 22.1 0.1 0.0002 20.9 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO18646.1 - 0.0037 16.4 0.9 0.0037 16.4 0.9 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KLO18646.1 - 0.0039 16.0 1.8 0.15 10.8 0.2 2.8 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 KLO18646.1 - 0.045 14.3 0.1 0.13 12.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KLO18646.1 - 0.059 12.7 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Coatomer_WDAD PF04053.14 KLO18647.1 - 0.0022 17.1 0.0 0.0054 15.8 0.0 1.6 1 1 0 1 1 1 1 Coatomer WD associated region PD40 PF07676.12 KLO18647.1 - 0.0092 15.9 0.1 9.4 6.3 0.1 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Glyco_hydro_3_C PF01915.22 KLO18648.1 - 8e-41 140.2 0.0 1.3e-40 139.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KLO18648.1 - 6.8e-40 137.4 0.0 9.6e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KLO18648.1 - 3.2e-22 78.4 0.1 5.6e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain PEMT PF04191.13 KLO18649.1 - 1.4e-51 173.3 14.6 3.2e-30 104.7 1.6 3.0 3 0 0 3 3 3 2 Phospholipid methyltransferase PID PF00640.23 KLO18649.1 - 0.0056 16.7 0.2 0.25 11.4 0.0 2.3 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) HECW_N PF16562.5 KLO18649.1 - 0.031 14.1 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Ins_allergen_rp PF06757.13 KLO18649.1 - 0.054 13.5 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification ApoLp-III PF07464.11 KLO18649.1 - 0.12 12.5 0.6 0.23 11.5 0.6 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) MAGI_u5 PF16666.5 KLO18649.1 - 1.8 8.7 3.7 0.76 9.9 0.3 2.1 2 0 0 2 2 2 0 Unstructured region on MAGI FUN14 PF04930.15 KLO18650.1 - 3.8e-19 68.9 1.5 4.5e-19 68.7 0.6 1.5 2 0 0 2 2 2 1 FUN14 family Nucleoporin2 PF04096.14 KLO18652.1 - 5.3e-45 153.2 0.0 9.3e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KLO18652.1 - 1e-17 64.7 304.6 8.6e-08 32.9 37.6 11.5 3 3 6 9 9 9 5 Nucleoporin FG repeat region Fes1 PF08609.10 KLO18653.1 - 4.2e-24 85.3 2.3 1.3e-23 83.6 0.4 2.5 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 SIL1 PF16782.5 KLO18653.1 - 0.00011 21.6 0.0 0.00014 21.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 HEAT PF02985.22 KLO18653.1 - 0.00052 20.0 0.1 1.5 9.3 0.0 3.4 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 KLO18653.1 - 0.0011 19.3 0.9 0.26 11.7 0.0 3.1 2 1 1 3 3 3 2 HEAT repeats Adaptin_N PF01602.20 KLO18653.1 - 0.0036 15.9 0.1 0.7 8.4 0.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 KLO18653.1 - 0.083 13.4 0.4 24 5.5 0.1 3.3 1 1 1 2 2 2 0 HEAT-like repeat DUF3566 PF12089.8 KLO18654.1 - 0.043 14.2 0.1 34 4.8 0.0 3.3 3 0 0 3 3 3 0 Transmembrane domain of unknown function (DUF3566) LETM1 PF07766.13 KLO18654.1 - 0.24 10.7 3.3 0.23 10.8 2.2 1.4 1 1 0 1 1 1 0 LETM1-like protein Peroxidase_2 PF01328.17 KLO18655.1 - 4.4e-52 177.3 0.0 5.9e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 ODV-E18 PF10717.9 KLO18656.1 - 0.098 12.5 0.1 0.098 12.5 0.1 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 NiFe_hyd_3_EhaA PF17367.2 KLO18656.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.6 3 0 0 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A MaoC_dehydratas PF01575.19 KLO18657.1 - 7.6e-27 93.3 0.0 1.2e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain NAD_binding_4 PF07993.12 KLO18658.1 - 1.2e-26 93.4 0.0 2.1e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KLO18658.1 - 1.3e-26 93.2 0.0 8e-25 87.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.21 KLO18658.1 - 3.5e-08 33.2 0.0 9.8e-08 31.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KLO18658.1 - 8.6e-07 29.2 0.2 2.3e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KLO18658.1 - 0.00048 19.2 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KLO18658.1 - 0.05 13.5 0.5 4.7 7.1 0.3 3.3 3 1 0 3 3 3 0 KR domain HTH_28 PF13518.6 KLO18659.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Isy1 PF06246.12 KLO18660.1 - 2.6e-93 312.3 1.2 4.3e-93 311.6 1.2 1.3 1 1 0 1 1 1 1 Isy1-like splicing family ADPrib_exo_Tox PF03496.14 KLO18660.1 - 0.068 12.5 0.2 0.098 12.0 0.2 1.3 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme Questin_oxidase PF14027.6 KLO18661.1 - 3.6e-85 286.5 0.0 4.3e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Pyr_redox_2 PF07992.14 KLO18662.1 - 7.3e-64 215.8 6.5 1e-63 215.4 6.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KLO18662.1 - 8.4e-42 141.9 3.6 1.6e-41 141.0 0.1 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KLO18662.1 - 5.4e-20 71.7 8.4 7.1e-18 64.9 1.8 3.5 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KLO18662.1 - 3.5e-11 43.1 11.2 2.5e-10 40.3 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 KLO18662.1 - 3e-09 36.4 9.7 3e-08 33.2 3.9 2.9 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KLO18662.1 - 1.7e-08 34.5 6.0 7.4e-05 22.9 0.8 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KLO18662.1 - 2.6e-08 33.5 7.7 1.4e-05 24.5 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO18662.1 - 1.7e-07 30.3 13.8 0.00014 20.7 0.6 4.1 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 KLO18662.1 - 8e-07 28.5 1.3 8e-07 28.5 1.3 3.7 3 1 0 4 4 4 2 FAD binding domain AlaDh_PNT_C PF01262.21 KLO18662.1 - 7.2e-06 25.4 0.7 0.018 14.4 0.2 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KLO18662.1 - 1.4e-05 24.4 1.2 0.0016 17.6 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KLO18662.1 - 0.00034 20.3 14.9 1.2 8.6 0.1 4.2 3 1 1 4 4 4 3 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KLO18662.1 - 0.0028 17.0 11.3 0.032 13.5 0.5 3.4 3 1 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 KLO18662.1 - 0.0049 16.1 0.1 0.0049 16.1 0.1 2.5 2 1 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KLO18662.1 - 0.014 14.4 2.3 0.36 9.8 0.0 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein Mqo PF06039.15 KLO18662.1 - 0.11 11.0 3.5 0.22 10.1 0.2 2.2 1 1 1 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Aldedh PF00171.22 KLO18663.1 - 1e-79 268.2 0.0 1.2e-79 268.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.18 KLO18663.1 - 0.00075 20.4 0.1 0.047 14.6 0.0 3.0 3 0 0 3 3 3 1 Fic/DOC family DUF3808 PF10300.9 KLO18664.1 - 1.4e-79 268.1 0.0 2.3e-79 267.4 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 KLO18664.1 - 0.0025 17.8 7.8 0.2 11.8 0.1 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KLO18664.1 - 0.0067 16.7 1.2 12 6.2 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Cyclin_C PF02984.19 KLO18664.1 - 0.12 12.4 0.0 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 Cyclin, C-terminal domain TPR_1 PF00515.28 KLO18664.1 - 0.56 10.1 7.6 6.5 6.7 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 KLO18665.1 - 0.00045 20.4 0.8 0.14 12.4 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Glyco_hydro_38N PF01074.22 KLO18666.1 - 7e-80 268.5 0.3 1e-79 267.9 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KLO18666.1 - 1.6e-51 175.4 0.0 2.5e-51 174.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KLO18666.1 - 2.4e-27 94.9 0.0 5.9e-27 93.6 0.0 1.7 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KLO18666.1 - 2e-08 34.2 0.0 4.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DUF3808 PF10300.9 KLO18667.1 - 1.8e-68 231.4 0.0 2.7e-68 230.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_MalT PF17874.1 KLO18667.1 - 0.15 11.4 3.5 0.61 9.4 0.0 2.6 3 0 0 3 3 3 0 MalT-like TPR region TPR_8 PF13181.6 KLO18667.1 - 0.87 10.0 3.9 13 6.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KLO18667.1 - 5.3 7.4 7.8 3.7 7.9 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat p450 PF00067.22 KLO18668.1 - 1.1e-33 116.7 0.0 1.5e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KLO18669.1 - 1.5e-19 70.4 0.0 1.5e-18 67.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO18669.1 - 7.5e-07 28.7 0.1 8.2e-05 22.0 0.1 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO18669.1 - 0.15 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase HAUS6_N PF14661.6 KLO18670.1 - 0.071 12.7 0.7 0.16 11.5 0.7 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus HOOK PF05622.12 KLO18670.1 - 0.15 10.2 1.8 0.23 9.6 1.8 1.1 1 0 0 1 1 1 0 HOOK protein Syntaxin-6_N PF09177.11 KLO18670.1 - 1.5 9.4 5.4 2.4 8.8 1.6 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal FAM184 PF15665.5 KLO18670.1 - 7.3 6.3 8.7 0.25 11.1 2.7 1.6 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B RPN6_N PF18055.1 KLO18671.1 - 1e-44 151.6 1.9 1.9e-44 150.8 0.8 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KLO18671.1 - 4.1e-16 59.4 0.7 1.2e-15 57.9 0.1 2.1 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KLO18671.1 - 1.1e-10 41.0 0.3 2.4e-10 40.0 0.3 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 KLO18671.1 - 0.035 13.7 0.3 0.035 13.7 0.3 1.8 2 0 0 2 2 2 0 DDRGK domain Peptidase_S28 PF05577.12 KLO18671.1 - 0.13 11.0 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Methyltransf_22 PF13383.6 KLO18672.1 - 2.2e-20 73.3 0.0 3.1e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KLO18672.1 - 1.3e-05 25.3 0.0 2.1e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain HLH PF00010.26 KLO18673.1 - 9.5e-14 51.1 0.2 9.5e-14 51.1 0.2 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3450 PF11932.8 KLO18673.1 - 0.054 12.8 2.8 0.032 13.6 0.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) BST2 PF16716.5 KLO18673.1 - 0.11 13.1 1.5 0.2 12.2 1.5 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 YabA PF06156.13 KLO18673.1 - 0.11 13.1 2.3 0.29 11.8 0.5 2.2 2 1 1 3 3 3 0 Initiation control protein YabA Na_H_Exchanger PF00999.21 KLO18674.1 - 1.1e-73 248.2 36.9 1.4e-73 247.9 36.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tim17 PF02466.19 KLO18674.1 - 0.022 15.1 0.3 13 6.2 0.0 2.7 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Methyltransf_23 PF13489.6 KLO18675.1 - 2e-14 53.8 0.0 3.2e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO18675.1 - 7.1e-13 48.6 0.0 9.2e-12 45.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO18675.1 - 9.4e-13 48.6 0.0 4.3e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO18675.1 - 3.6e-11 43.6 0.1 4.9e-10 40.0 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO18675.1 - 1.7e-09 38.3 0.1 1.2e-08 35.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KLO18675.1 - 2.2e-05 24.1 0.0 0.0045 16.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KLO18675.1 - 3.2e-05 23.5 0.0 0.00037 20.0 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KLO18675.1 - 0.00066 19.8 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase GidB PF02527.15 KLO18675.1 - 0.0011 18.4 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.6 KLO18675.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KLO18675.1 - 0.087 12.2 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KLO18675.1 - 0.13 11.6 0.0 12 5.2 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 KLO18675.1 - 0.15 11.8 0.0 2 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_8 PF05148.15 KLO18675.1 - 0.2 11.5 0.0 0.65 9.8 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase F-box-like PF12937.7 KLO18676.1 - 0.0064 16.4 0.1 0.026 14.4 0.1 2.1 1 0 0 1 1 1 1 F-box-like ECH_1 PF00378.20 KLO18676.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase TPR_2 PF07719.17 KLO18677.1 - 2.3e-17 61.6 19.1 0.0025 17.8 0.2 11.3 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 KLO18677.1 - 7.7e-16 58.4 10.5 0.00089 19.7 0.1 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KLO18677.1 - 4.9e-14 51.3 2.9 0.88 9.9 0.1 10.8 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_1 PF00515.28 KLO18677.1 - 1.1e-12 47.2 12.9 5.9e-05 22.7 0.2 9.9 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_11 PF13414.6 KLO18677.1 - 1.4e-11 43.8 1.1 0.0032 17.1 0.1 7.4 9 0 0 9 9 9 2 TPR repeat TPR_14 PF13428.6 KLO18677.1 - 2.8e-10 40.1 18.1 0.87 10.6 0.1 11.2 9 2 3 12 12 11 2 Tetratricopeptide repeat TPR_7 PF13176.6 KLO18677.1 - 1.3e-09 37.4 11.3 0.79 9.9 0.1 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 KLO18677.1 - 1e-08 35.0 2.9 5.7 7.6 0.0 8.5 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 KLO18677.1 - 6.2e-08 32.8 22.1 0.36 11.2 0.2 10.7 11 2 1 12 12 11 2 Tetratricopeptide repeat TPR_16 PF13432.6 KLO18677.1 - 8.2e-06 26.4 17.6 0.02 15.5 0.4 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KLO18677.1 - 3.5e-05 24.3 0.5 0.13 12.7 0.1 3.8 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation BTAD PF03704.17 KLO18677.1 - 0.00028 21.3 4.0 0.24 11.8 0.0 3.6 3 0 0 3 3 3 2 Bacterial transcriptional activator domain TPR_6 PF13174.6 KLO18677.1 - 0.00083 19.8 19.7 5.7 7.8 0.0 9.2 11 0 0 11 11 8 1 Tetratricopeptide repeat TPR_20 PF14561.6 KLO18677.1 - 0.011 16.1 4.3 0.066 13.5 0.6 4.2 6 0 0 6 6 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO18677.1 - 0.02 15.1 5.3 22 5.4 0.0 5.7 5 1 1 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 KLO18677.1 - 0.19 11.1 7.0 1.9 7.8 0.1 3.6 4 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 KLO18677.1 - 0.83 9.8 14.5 2.7 8.2 0.1 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 KLO18677.1 - 1.8 8.5 17.7 4.8 7.2 0.1 7.1 9 0 0 9 9 9 0 Tetratricopeptide repeat MFS_1 PF07690.16 KLO18678.1 - 2.9e-38 131.7 29.3 2.9e-38 131.7 29.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KLO18679.1 - 3e-40 138.2 27.5 3e-40 138.2 27.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO18679.1 - 4e-09 35.9 6.0 4e-09 35.9 6.0 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter PapG_C PF03628.13 KLO18681.1 - 0.076 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 PapG chaperone-binding domain Aldo_ket_red PF00248.21 KLO18682.1 - 1.3e-40 139.4 0.0 1.5e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Shikimate_DH PF01488.20 KLO18683.1 - 0.14 12.3 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ctr PF04145.15 KLO18684.1 - 5.9e-29 101.6 0.0 6.9e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.19 KLO18685.1 - 1.1e-19 70.8 7.7 1.1e-19 70.8 7.7 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KLO18685.1 - 3.4e-10 40.3 0.0 1.6e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KLO18685.1 - 1.3e-09 38.1 0.0 2.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain VGCC_beta4Aa_N PF12052.8 KLO18686.1 - 2.8 8.1 6.2 0.21 11.7 1.3 1.7 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal p450 PF00067.22 KLO18687.1 - 3.6e-74 250.2 0.0 4.9e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO18689.1 - 2.6e-73 247.4 0.0 3.6e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HIG_1_N PF04588.13 KLO18689.1 - 0.086 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Hypoxia induced protein conserved region PAM2 PF07145.15 KLO18689.1 - 0.44 10.4 4.1 3 7.7 0.1 3.0 3 0 0 3 3 3 0 Ataxin-2 C-terminal region p450 PF00067.22 KLO18690.1 - 3.5e-59 200.8 0.0 2.7e-58 197.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Elicitin PF00964.17 KLO18691.1 - 0.051 13.7 4.1 0.21 11.7 4.1 2.1 1 0 0 1 1 1 0 Elicitin Alpha-amylase PF00128.24 KLO18692.1 - 3.4e-59 201.1 0.4 5.9e-59 200.3 0.4 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KLO18692.1 - 1.9e-11 44.1 0.1 4.4e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) PLA2_B PF01735.18 KLO18693.1 - 8.8e-100 334.4 0.9 1.4e-99 333.7 0.9 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain SNF2_N PF00176.23 KLO18694.1 - 3.2e-63 213.6 0.1 4.4e-63 213.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO18694.1 - 4.1e-15 56.1 0.0 1e-14 54.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KLO18694.1 - 5.6e-07 29.3 4.4 1.2e-06 28.3 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO18694.1 - 6e-07 29.7 5.7 2e-06 28.0 5.7 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KLO18694.1 - 8.5e-06 25.6 6.0 8.5e-06 25.6 6.0 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KLO18694.1 - 1.1e-05 25.3 1.6 1.1e-05 25.3 1.6 2.3 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KLO18694.1 - 1.3e-05 25.0 4.5 1.3e-05 25.0 4.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KLO18694.1 - 4.8e-05 23.1 6.6 0.00026 20.8 6.6 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KLO18694.1 - 5.2e-05 23.3 0.1 0.00076 19.5 0.1 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 KLO18694.1 - 0.00012 22.1 5.6 0.00029 20.9 5.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KLO18694.1 - 0.00012 21.8 2.0 0.00035 20.3 2.1 1.9 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 KLO18694.1 - 0.003 17.4 1.5 0.42 10.5 0.1 3.3 2 0 0 2 2 2 1 Rad50 zinc hook motif AGOG PF09171.10 KLO18694.1 - 0.0084 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 N-glycosylase/DNA lyase zf-rbx1 PF12678.7 KLO18694.1 - 0.02 15.1 3.8 0.051 13.9 3.8 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain DEAD_2 PF06733.15 KLO18694.1 - 0.063 12.9 0.5 0.76 9.4 0.0 2.3 2 0 0 2 2 2 0 DEAD_2 SWI2_SNF2 PF18766.1 KLO18694.1 - 0.078 12.6 0.1 8.2 6.0 0.0 2.6 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Prok-RING_4 PF14447.6 KLO18694.1 - 0.19 11.6 10.1 0.089 12.7 6.0 2.5 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KLO18694.1 - 0.38 10.8 1.4 0.85 9.7 1.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.21 KLO18694.1 - 0.39 10.9 6.2 2.3 8.4 6.2 2.3 1 1 0 1 1 1 0 FYVE zinc finger Prok-RING_1 PF14446.6 KLO18694.1 - 6.4 6.8 9.2 6.6 6.8 1.7 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 SAP PF02037.27 KLO18695.1 - 0.00032 20.4 0.3 0.00053 19.7 0.3 1.4 1 0 0 1 1 1 1 SAP domain HTH_10 PF04967.12 KLO18695.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain LcrG PF07216.12 KLO18695.1 - 0.16 11.9 0.2 0.39 10.7 0.2 1.6 1 1 0 1 1 1 0 LcrG protein DUF4965 PF16335.5 KLO18697.1 - 2.5e-45 154.2 2.3 4.7e-45 153.3 2.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO18697.1 - 5.8e-38 131.0 0.3 5.8e-38 131.0 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 KLO18697.1 - 4.7e-09 36.4 0.0 1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF2273 PF10031.9 KLO18698.1 - 0.0049 16.8 2.8 0.0081 16.1 2.8 1.3 1 0 0 1 1 1 1 Small integral membrane protein (DUF2273) ANXA2R PF15721.5 KLO18698.1 - 0.083 13.4 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Annexin-2 receptor PTP_tm PF18861.1 KLO18698.1 - 0.17 11.8 0.2 0.24 11.4 0.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4965 PF16335.5 KLO18699.1 - 6e-46 156.3 1.1 1.1e-45 155.4 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KLO18699.1 - 1.1e-41 143.1 1.4 1.4e-39 136.3 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KLO18699.1 - 4.2e-36 124.9 1.9 5e-36 124.7 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KLO18699.1 - 0.0019 17.7 0.0 0.0093 15.5 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KLO18699.1 - 0.016 14.7 0.3 0.027 14.0 0.3 1.3 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF4912 PF16258.5 KLO18700.1 - 0.035 14.3 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4912) DUF5127 PF17168.4 KLO18701.1 - 2.1e-49 168.4 0.3 3.6e-49 167.6 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KLO18701.1 - 7.5e-44 149.4 3.3 1.3e-43 148.7 1.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KLO18701.1 - 3.3e-41 141.5 0.2 8.3e-41 140.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Glyco_hydr_116N PF12215.8 KLO18701.1 - 0.004 16.7 0.2 0.0079 15.7 0.2 1.5 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF4964 PF16334.5 KLO18701.1 - 0.014 14.9 0.0 0.047 13.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) RRM_1 PF00076.22 KLO18703.1 - 9.4e-32 108.7 0.5 1.1e-15 57.2 0.0 2.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KLO18703.1 - 6.7e-12 45.4 0.3 4.5e-07 29.9 0.0 3.5 2 2 1 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KLO18703.1 - 0.0054 16.7 0.0 4.8 7.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KLO18703.1 - 0.12 12.4 0.0 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif VHS PF00790.19 KLO18704.1 - 9.4e-09 35.3 0.2 2e-08 34.2 0.2 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KLO18704.1 - 8.2e-08 32.5 0.0 0.0032 17.7 0.0 2.5 2 0 0 2 2 2 2 GAT domain FLILHELTA PF10306.9 KLO18705.1 - 5.3e-10 39.6 0.0 1.1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KLO18705.1 - 0.003 18.1 0.0 0.0055 17.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) WD40 PF00400.32 KLO18706.1 - 6.4e-05 23.6 7.9 0.0081 17.0 0.2 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box-like PF12937.7 KLO18706.1 - 0.0015 18.4 0.1 0.0038 17.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO18706.1 - 0.0019 18.0 0.2 0.0064 16.3 0.0 1.9 2 0 0 2 2 2 1 F-box domain UIM PF02809.20 KLO18706.1 - 0.0029 17.4 6.8 0.0035 17.1 5.0 2.2 2 0 0 2 2 2 1 Ubiquitin interaction motif P16-Arc PF04699.14 KLO18707.1 - 9.2e-54 182.0 0.0 1e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 KLO18707.1 - 0.059 13.7 0.0 0.088 13.1 0.0 1.2 1 0 0 1 1 1 0 Dip2/Utp12 Family PH PF00169.29 KLO18709.1 - 6.9e-06 26.5 0.0 9.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 KLO18710.1 - 2.7e-39 135.0 0.0 3.1e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO18710.1 - 1.9e-36 125.8 0.0 2.3e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KLO18710.1 - 0.0016 17.3 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO18710.1 - 0.039 13.3 0.0 0.069 12.5 0.0 1.4 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 KLO18710.1 - 0.041 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SWIB PF02201.18 KLO18711.1 - 5.9e-21 74.1 0.3 1.4e-20 73.0 0.3 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain BAR PF03114.18 KLO18712.1 - 6.2e-38 130.8 2.4 1e-37 130.1 2.4 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KLO18712.1 - 5e-14 51.6 0.1 1e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KLO18712.1 - 4.1e-13 49.0 0.1 9.2e-13 47.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KLO18712.1 - 8e-11 41.5 0.0 1.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MAT1 PF06391.13 KLO18712.1 - 0.041 13.7 2.5 0.11 12.3 2.5 1.7 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 TF_Zn_Ribbon PF08271.12 KLO18712.1 - 0.33 10.5 4.3 0.64 9.6 4.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DUF678 PF05077.12 KLO18713.1 - 0.081 13.1 1.4 0.16 12.2 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Sporozoite_P67 PF05642.11 KLO18714.1 - 0.32 9.0 15.5 0.38 8.8 15.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ecl1 PF12855.7 KLO18714.1 - 8.8 7.5 16.9 12 7.1 16.9 1.1 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Glyco_hydro_3_C PF01915.22 KLO18715.1 - 5.6e-51 173.4 0.0 1.9e-50 171.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KLO18715.1 - 3.9e-37 128.3 0.1 6.6e-37 127.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KLO18715.1 - 1.9e-20 72.7 0.1 4.4e-20 71.6 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain CholecysA-Rec_N PF09193.10 KLO18715.1 - 0.24 11.4 0.3 0.86 9.7 0.1 2.1 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal DIOX_N PF14226.6 KLO18717.1 - 1.3e-14 55.0 0.0 2.3e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO18717.1 - 4.4e-13 49.6 0.0 1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA_2 PF07724.14 KLO18718.1 - 8.2e-48 162.7 0.0 5.2e-45 153.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KLO18718.1 - 2.2e-32 111.1 3.4 2.7e-32 110.8 0.1 2.4 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KLO18718.1 - 9.1e-21 73.7 0.2 3.1e-20 72.0 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KLO18718.1 - 2.4e-18 66.8 0.1 4.4e-09 36.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KLO18718.1 - 1.3e-16 60.8 0.0 3.8e-10 39.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KLO18718.1 - 4.8e-09 36.8 7.6 6e-05 23.5 0.1 4.1 3 2 2 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 KLO18718.1 - 9.6e-09 35.6 0.2 0.0058 16.9 0.0 3.8 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 KLO18718.1 - 7.7e-07 29.0 0.0 3e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 KLO18718.1 - 5.8e-06 26.9 0.0 0.19 12.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KLO18718.1 - 1.9e-05 25.2 0.6 0.016 15.7 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_7 PF12775.7 KLO18718.1 - 2.2e-05 24.1 0.0 0.053 13.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KLO18718.1 - 2.7e-05 24.0 0.2 0.22 11.2 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KLO18718.1 - 3.3e-05 23.4 0.1 0.44 9.9 0.0 3.1 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KLO18718.1 - 5e-05 23.3 0.9 0.15 11.9 0.0 3.9 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea RuvB_N PF05496.12 KLO18718.1 - 6.8e-05 22.7 0.2 0.86 9.3 0.2 3.2 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KLO18718.1 - 7.3e-05 22.6 0.0 0.045 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KLO18718.1 - 0.00022 21.3 0.0 0.48 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 KLO18718.1 - 0.00042 20.5 0.0 0.43 10.8 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KLO18718.1 - 0.00052 20.0 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KLO18718.1 - 0.00076 19.8 3.3 0.41 10.9 0.0 3.7 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KLO18718.1 - 0.001 19.4 0.0 2.9 8.3 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 KLO18718.1 - 0.0027 17.4 0.3 0.61 9.8 0.0 3.7 2 1 1 3 3 3 1 AAA domain AAA_29 PF13555.6 KLO18718.1 - 0.0082 15.9 0.0 4.9 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 KLO18718.1 - 0.011 15.7 0.0 0.87 9.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 KLO18718.1 - 0.014 15.4 0.0 8 6.3 0.0 3.5 3 0 0 3 3 3 0 NTPase AAA_19 PF13245.6 KLO18718.1 - 0.016 15.6 0.2 0.35 11.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 KLO18718.1 - 0.02 14.9 0.0 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 KLO18718.1 - 0.021 14.6 0.0 7.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_33 PF13671.6 KLO18718.1 - 0.023 14.9 0.0 5 7.3 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KLO18718.1 - 0.025 14.4 0.4 6.6 6.4 0.0 2.9 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 KLO18718.1 - 0.028 14.0 0.0 3.1 7.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KLO18718.1 - 0.037 14.5 7.3 0.67 10.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 KLO18718.1 - 0.097 12.4 0.0 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KLO18718.1 - 0.11 12.3 0.0 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DNA_pol3_delta2 PF13177.6 KLO18718.1 - 0.11 12.3 0.0 0.89 9.3 0.0 2.3 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_11 PF13086.6 KLO18718.1 - 0.66 9.7 5.0 2 8.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KLO18718.1 - 0.68 9.5 4.8 1.8 8.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain Atg14 PF10186.9 KLO18718.1 - 3.6 6.6 5.1 5.8 5.9 5.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2062 PF09835.9 KLO18719.1 - 0.0095 15.8 0.3 0.02 14.8 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2062) Podoplanin PF05808.11 KLO18719.1 - 0.034 14.2 7.0 0.059 13.5 7.0 1.3 1 0 0 1 1 1 0 Podoplanin Amnionless PF14828.6 KLO18719.1 - 0.053 12.3 0.4 0.077 11.8 0.1 1.4 2 0 0 2 2 2 0 Amnionless Protocadherin PF08374.11 KLO18720.1 - 0.035 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Protocadherin tRNA-synt_2_TM PF16995.5 KLO18721.1 - 0.032 13.9 0.2 0.055 13.2 0.2 1.3 1 0 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase Gram_pos_anchor PF00746.21 KLO18721.1 - 1.5 8.9 8.1 8.3 6.5 0.1 3.1 3 0 0 3 3 3 0 LPXTG cell wall anchor motif RAP1 PF07218.11 KLO18721.1 - 4.9 5.3 6.5 6.3 5.0 6.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CE2_N PF17996.1 KLO18722.1 - 0.0058 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal adh_short PF00106.25 KLO18723.1 - 5.6e-28 97.7 0.0 6.3e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO18723.1 - 2e-22 79.9 0.0 2.3e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO18723.1 - 1e-10 41.8 0.1 2.6e-10 40.5 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO18723.1 - 1.1e-06 28.3 0.1 4.4e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO18723.1 - 0.00038 19.9 0.1 0.0012 18.3 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KLO18723.1 - 0.0004 20.3 0.0 0.00068 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KLO18723.1 - 0.00042 19.5 0.0 0.00057 19.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KLO18723.1 - 0.0025 17.4 0.1 0.0033 17.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_7 PF13241.6 KLO18723.1 - 0.029 14.8 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF1776 PF08643.10 KLO18723.1 - 0.055 12.8 0.1 0.32 10.3 0.0 1.8 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) YjeF_N PF03853.15 KLO18723.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 2 0 0 2 2 2 0 YjeF-related protein N-terminus Polysacc_synt_2 PF02719.15 KLO18723.1 - 0.094 11.8 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PEMT PF04191.13 KLO18724.1 - 8.9e-32 109.7 4.0 8.9e-32 109.7 4.0 1.7 2 1 0 2 2 2 1 Phospholipid methyltransferase ABC1 PF03109.16 KLO18725.1 - 1.1e-25 90.1 0.0 1.9e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KLO18725.1 - 0.096 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KLO18726.1 - 5.4e-46 157.0 0.0 2.4e-45 154.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KLO18726.1 - 3e-36 125.1 0.0 4.8e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PH_10 PF15411.6 KLO18726.1 - 3.8e-07 30.4 0.0 7.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KLO18726.1 - 8e-07 29.5 0.1 1.5e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain APH PF01636.23 KLO18726.1 - 0.00084 19.3 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family CDC24 PF06395.11 KLO18726.1 - 0.007 16.6 0.0 0.042 14.1 0.0 2.3 1 1 0 1 1 1 1 CDC24 Calponin Pkinase_fungal PF17667.1 KLO18726.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KLO18726.1 - 0.048 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KLO18726.1 - 0.051 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family DIOX_N PF14226.6 KLO18728.1 - 1.5e-15 58.0 0.0 2.6e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO18728.1 - 9.6e-13 48.5 0.0 1.9e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KLO18729.1 - 1.3e-16 60.9 0.0 2.7e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KLO18729.1 - 6.7e-15 55.9 0.0 1.6e-14 54.6 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal UQ_con PF00179.26 KLO18730.1 - 5.5e-38 129.8 0.0 8.7e-38 129.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KLO18730.1 - 0.21 11.3 0.0 0.4 10.4 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B RRM_1 PF00076.22 KLO18731.1 - 8.4e-19 67.2 0.0 1.5e-09 37.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMA PF00403.26 KLO18731.1 - 0.14 12.6 0.0 22 5.6 0.0 2.6 2 0 0 2 2 2 0 Heavy-metal-associated domain PaaX PF07848.12 KLO18732.1 - 0.23 11.7 0.1 0.23 11.7 0.1 1.8 2 0 0 2 2 2 0 PaaX-like protein Glyco_transf_20 PF00982.21 KLO18734.1 - 3.1e-152 507.6 0.0 4.3e-152 507.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KLO18734.1 - 2.8e-21 75.7 0.0 4.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Metallophos PF00149.28 KLO18735.1 - 8.6e-36 124.4 0.0 1.2e-35 123.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KLO18735.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 KLO18735.1 - 0.0033 17.8 0.1 0.0077 16.7 0.1 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain EMC1_C PF07774.13 KLO18736.1 - 9.9e-73 244.3 0.1 1.8e-72 243.5 0.1 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KLO18736.1 - 2.6e-12 46.8 1.0 5.1e-08 32.8 0.1 3.4 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 KLO18736.1 - 3.2e-05 23.6 3.9 0.16 11.9 0.1 4.2 4 0 0 4 4 4 2 PQQ enzyme repeat Glyco_hydro_18 PF00704.28 KLO18737.1 - 1e-59 202.8 1.8 1.2e-59 202.6 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL10 PF02638.15 KLO18737.1 - 0.046 12.8 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 Pkinase PF00069.25 KLO18738.1 - 5.3e-38 130.9 0.0 1.4e-27 96.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO18738.1 - 1.6e-13 50.6 0.0 1e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KLO18738.1 - 0.00083 18.8 0.0 0.28 10.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KLO18738.1 - 0.62 9.9 2.0 0.59 10.0 0.1 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family ApoO PF09769.9 KLO18740.1 - 1.6e-27 96.0 0.2 3.6e-27 94.9 0.0 1.7 2 0 0 2 2 2 1 Apolipoprotein O UCH PF00443.29 KLO18742.1 - 5.2e-42 144.1 0.0 6.4e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KLO18742.1 - 5e-11 42.8 0.2 7.2e-05 22.5 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KLO18742.1 - 1.2e-07 31.3 0.0 3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Bap31 PF05529.12 KLO18743.1 - 1.8e-42 144.4 4.4 2.6e-42 143.9 4.4 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KLO18743.1 - 4.9e-13 48.9 6.2 4.9e-13 48.9 6.2 1.5 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain PI3K_P85_iSH2 PF16454.5 KLO18743.1 - 0.0014 18.3 1.6 0.0014 18.3 1.6 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ASF1_hist_chap PF04729.13 KLO18744.1 - 5.9e-61 204.9 0.0 7.7e-61 204.5 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone FoP_duplication PF13865.6 KLO18744.1 - 0.1 13.2 0.2 4 8.1 0.1 2.2 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Arrestin_N PF00339.29 KLO18745.1 - 3.9e-05 23.7 0.0 0.017 15.2 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain BAG PF02179.16 KLO18746.1 - 7.5e-08 32.7 0.2 3e-07 30.8 0.2 2.0 1 0 0 1 1 1 1 BAG domain IQ PF00612.27 KLO18746.1 - 0.0031 17.2 0.1 0.011 15.4 0.1 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF1151 PF06625.11 KLO18746.1 - 3.1 7.8 9.8 8.8 6.3 9.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) DUF1746 PF08508.10 KLO18749.1 - 0.087 13.2 1.6 0.14 12.5 0.3 1.9 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) PLA2_B PF01735.18 KLO18750.1 - 1.5e-98 330.4 0.2 2.1e-98 329.9 0.2 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 KLO18750.1 - 0.041 14.0 4.9 0.09 12.9 4.9 1.8 1 1 0 1 1 1 0 Patatin-like phospholipase Gp_dh_C PF02800.20 KLO18751.1 - 9.4e-69 230.0 0.0 1.4e-68 229.5 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KLO18751.1 - 4.1e-38 129.8 0.2 8.2e-38 128.8 0.2 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KLO18751.1 - 0.011 15.8 0.9 0.041 14.0 0.2 2.4 2 1 1 3 3 3 0 Dihydrodipicolinate reductase, N-terminus RasGEF PF00617.19 KLO18752.1 - 2.1e-30 106.2 0.0 4.4e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KLO18752.1 - 6.2e-09 36.1 1.1 1.8e-08 34.5 1.1 1.9 1 1 0 1 1 1 1 RasGEF N-terminal motif AA_permease_2 PF13520.6 KLO18753.1 - 3.9e-54 184.1 40.5 4.7e-54 183.8 40.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3446 PF11928.8 KLO18753.1 - 0.07 13.4 2.7 1.3 9.4 0.0 2.8 2 0 0 2 2 2 0 Early growth response N-terminal domain PPR_2 PF13041.6 KLO18754.1 - 4.6e-11 42.7 0.1 0.00067 19.8 0.0 6.9 6 3 2 8 8 8 2 PPR repeat family PPR PF01535.20 KLO18754.1 - 3.9e-09 36.1 3.4 3.6 8.1 0.0 7.9 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.7 KLO18754.1 - 0.0001 21.9 0.1 0.076 12.7 0.0 4.5 7 0 0 7 7 7 1 PPR repeat PPR_3 PF13812.6 KLO18754.1 - 0.00015 21.8 0.0 0.4 10.8 0.0 4.6 5 0 0 5 5 5 1 Pentatricopeptide repeat domain TPR_14 PF13428.6 KLO18754.1 - 0.024 15.5 1.3 1.9 9.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat CAS_CSE1 PF03378.15 KLO18755.1 - 4.2e-116 388.1 1.3 8.5e-116 387.0 0.6 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KLO18755.1 - 1.1e-96 323.9 0.0 2.2e-96 322.9 0.0 1.6 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KLO18755.1 - 2.7e-09 36.8 0.0 3.2e-08 33.4 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KLO18755.1 - 1.2e-08 35.1 0.1 1.9e-05 24.7 0.0 4.5 5 0 0 5 5 5 1 Exportin 1-like protein HEAT PF02985.22 KLO18755.1 - 0.25 11.7 2.3 2.5 8.6 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat IQ PF00612.27 KLO18756.1 - 0.001 18.7 0.4 0.003 17.2 0.4 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Gyro_capsid PF04162.12 KLO18756.1 - 2.2 6.7 5.1 4.3 5.7 5.1 1.4 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) VPS28 PF03997.12 KLO18757.1 - 1.9e-70 236.4 0.0 2.2e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein HSP70 PF00012.20 KLO18758.1 - 2e-66 224.5 10.2 1.3e-63 215.2 0.1 3.5 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KLO18758.1 - 0.0003 19.7 0.0 0.00063 18.6 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein MID_MedPIWI PF18296.1 KLO18758.1 - 8.4 6.1 8.0 6.6 6.4 4.3 2.3 2 0 0 2 2 2 0 MID domain of medPIWI Membr_traf_MHD PF10540.9 KLO18759.1 - 1.5e-24 86.8 0.5 6.4e-11 42.6 0.0 2.9 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KLO18759.1 - 2.9e-10 40.4 0.0 7.7e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain NAPRTase PF04095.16 KLO18759.1 - 0.15 11.7 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Phtf-FEM1B_bdg PF12129.8 KLO18760.1 - 0.033 14.0 0.0 1.8 8.4 0.0 2.2 1 1 1 2 2 2 0 Male germ-cell putative homeodomain transcription factor SRI PF08236.11 KLO18762.1 - 6.2e-19 68.0 8.6 6.2e-19 68.0 8.6 2.8 1 1 1 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KLO18762.1 - 7.2e-17 62.3 0.2 7.2e-17 62.3 0.2 3.6 2 2 0 2 2 2 1 SET domain AWS PF17907.1 KLO18762.1 - 4.4e-12 45.8 8.6 4.4e-12 45.8 8.6 2.0 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 KLO18762.1 - 0.006 16.6 0.2 0.006 16.6 0.2 4.5 5 0 0 5 5 5 1 TFIIS helical bundle-like domain DUF2868 PF11067.8 KLO18762.1 - 0.098 12.1 4.4 0.25 10.8 4.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) F-box-like PF12937.7 KLO18763.1 - 0.056 13.3 0.1 0.2 11.5 0.1 2.0 1 1 0 1 1 1 0 F-box-like RNA_pol_I_A49 PF06870.12 KLO18764.1 - 1.9e-107 359.5 3.3 2.2e-107 359.3 3.3 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Polyketide_cyc2 PF10604.9 KLO18765.1 - 6.5e-09 36.2 0.1 7.3e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KLO18765.1 - 4.8e-06 26.8 0.1 5.8e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport G-alpha PF00503.20 KLO18768.1 - 3.1e-111 372.0 0.0 3.8e-111 371.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO18768.1 - 1.9e-09 37.2 0.0 7.3e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Zeta_toxin PF06414.12 KLO18768.1 - 0.0033 16.7 0.1 0.05 12.9 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin TniB PF05621.11 KLO18768.1 - 0.0051 16.2 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 KLO18768.1 - 0.011 15.9 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KLO18768.1 - 0.044 13.5 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KLO18768.1 - 0.1 12.3 0.1 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KLO18768.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRRM_C PF15230.6 KLO18770.1 - 5.8e-05 23.6 5.0 5.8e-05 23.6 5.0 2.0 2 1 0 2 2 2 1 Serine/arginine repetitive matrix protein C-terminus DUF3421 PF11901.8 KLO18774.1 - 0.027 14.5 0.1 0.066 13.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3421) MltA PF03562.17 KLO18775.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 MltA specific insert domain APH PF01636.23 KLO18778.1 - 4.1e-14 53.1 0.1 5.3e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KLO18778.1 - 0.021 14.0 0.0 0.079 12.1 0.0 1.8 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.20 KLO18778.1 - 0.16 11.2 0.0 0.39 10.0 0.0 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase DPM2 PF07297.12 KLO18780.1 - 8.3e-26 90.1 0.6 9.4e-26 89.9 0.6 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KLO18780.1 - 3.6e-05 23.7 0.4 3.8e-05 23.6 0.4 1.1 1 0 0 1 1 1 1 PIG-P ApbA PF02558.16 KLO18780.1 - 0.019 14.6 0.1 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RF-1 PF00472.20 KLO18782.1 - 1.6e-23 82.8 1.2 3.7e-23 81.7 1.2 1.6 1 0 0 1 1 1 1 RF-1 domain Pox_MCEL PF03291.16 KLO18784.1 - 6.1e-80 268.8 0.0 1.1e-79 268.0 0.0 1.3 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KLO18784.1 - 3e-07 31.0 0.0 9.5e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO18784.1 - 1.7e-05 24.8 0.0 2.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO18784.1 - 5e-05 23.9 0.2 0.00024 21.7 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO18784.1 - 0.00023 21.9 0.0 0.0055 17.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KLO18784.1 - 0.0012 18.1 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.6 KLO18784.1 - 0.0086 15.9 0.0 0.068 13.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain DUF4211 PF13926.6 KLO18785.1 - 4.9e-31 107.7 0.1 1.4e-30 106.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) PMAIP1 PF15150.6 KLO18785.1 - 0.24 11.3 2.2 13 5.7 0.1 2.9 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced Pkinase_fungal PF17667.1 KLO18786.1 - 2.8e-91 306.3 3.4 2.8e-91 306.3 3.4 2.4 3 1 0 3 3 3 1 Fungal protein kinase Pkinase PF00069.25 KLO18786.1 - 2.9e-07 30.1 0.1 2.9e-07 30.1 0.1 2.4 3 0 0 3 3 3 1 Protein kinase domain Kdo PF06293.14 KLO18786.1 - 2.6e-05 23.7 0.6 7.2e-05 22.2 0.3 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KLO18786.1 - 0.011 15.1 0.2 0.032 13.5 0.1 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase DUF745 PF05335.13 KLO18786.1 - 0.17 11.6 2.9 0.35 10.6 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) PhoD PF09423.10 KLO18787.1 - 6e-07 28.8 0.1 0.016 14.3 0.0 2.4 3 0 0 3 3 3 2 PhoD-like phosphatase Haem_degrading PF03928.14 KLO18787.1 - 0.028 14.5 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Haem-degrading SPRY PF00622.28 KLO18788.1 - 7.3e-10 39.0 0.2 3.7e-06 27.1 0.0 3.1 2 1 1 3 3 3 2 SPRY domain UQ_con PF00179.26 KLO18789.1 - 1.6e-27 95.8 0.0 1.9e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KLO18789.1 - 0.0016 18.3 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 UEV domain BRE PF06113.12 KLO18789.1 - 0.0052 15.7 0.1 0.006 15.5 0.1 1.1 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) RWD PF05773.22 KLO18789.1 - 0.039 14.2 0.0 0.076 13.3 0.0 1.6 1 1 0 1 1 1 0 RWD domain Spo0A_C PF08769.11 KLO18789.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal UQ_con PF00179.26 KLO18790.1 - 1.1e-33 115.8 0.0 1.3e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KLO18790.1 - 0.026 14.8 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 RWD domain BTB PF00651.31 KLO18793.1 - 0.0064 16.7 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Nt_Gln_amidase PF09764.9 KLO18794.1 - 3.1e-55 186.6 0.0 3.5e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase TF_Zn_Ribbon PF08271.12 KLO18795.1 - 0.027 14.0 1.5 0.06 12.9 1.5 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Glycos_transf_1 PF00534.20 KLO18796.1 - 8.2e-19 67.8 0.0 1.8e-18 66.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KLO18796.1 - 5.9e-12 46.2 0.0 1.9e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KLO18796.1 - 7.8e-05 23.0 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 OTCace PF00185.24 KLO18798.1 - 7e-45 152.9 0.0 9.8e-45 152.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KLO18798.1 - 2.7e-43 147.5 0.0 4.2e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CAP_N PF01213.19 KLO18799.1 - 1.1e-99 334.0 0.4 1.4e-99 333.6 0.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KLO18799.1 - 2.8e-60 202.5 3.9 3.8e-60 202.0 3.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Mito_fiss_reg PF05308.11 KLO18799.1 - 0.00084 19.5 6.6 0.21 11.6 0.2 2.3 2 0 0 2 2 2 2 Mitochondrial fission regulator TBCC PF07986.12 KLO18799.1 - 0.13 12.0 5.7 0.13 12.0 3.7 1.8 1 1 1 2 2 2 0 Tubulin binding cofactor C PRIMA1 PF16101.5 KLO18799.1 - 6.6 6.8 21.3 5.5 7.1 7.9 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DNA_pol_phi PF04931.13 KLO18800.1 - 6.7e-212 705.7 15.2 6.7e-212 705.7 15.2 2.7 3 0 0 3 3 3 1 DNA polymerase phi YjeF_N PF03853.15 KLO18800.1 - 0.14 12.1 0.0 0.47 10.3 0.0 1.9 1 0 0 1 1 1 0 YjeF-related protein N-terminus MutS_V PF00488.21 KLO18801.1 - 1.2e-69 234.1 1.0 2.4e-69 233.1 0.5 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KLO18801.1 - 1.1e-33 117.1 0.3 1.1e-33 117.1 0.3 2.2 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KLO18801.1 - 2.2e-27 95.5 0.0 5.1e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KLO18801.1 - 1.5e-09 38.2 0.1 6.4e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KLO18801.1 - 1.5e-07 31.7 0.1 1.6e-06 28.4 0.0 2.8 3 0 0 3 3 3 1 MutS family domain IV ATP12 PF07542.11 KLO18802.1 - 2.2e-43 147.4 0.2 4.2e-43 146.5 0.0 1.5 2 0 0 2 2 2 1 ATP12 chaperone protein Glyco_hydro_cc PF11790.8 KLO18803.1 - 0.0011 18.6 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Linker_histone PF00538.19 KLO18805.1 - 4.5e-21 75.0 0.1 4.5e-21 75.0 0.1 2.3 2 0 0 2 2 2 1 linker histone H1 and H5 family AMP-binding PF00501.28 KLO18806.1 - 2.2e-13 49.6 0.0 4.6e-13 48.5 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme MTD PF01993.18 KLO18806.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Linker_histone PF00538.19 KLO18807.1 - 2e-23 82.5 0.0 2e-23 82.5 0.0 2.3 3 1 0 3 3 3 1 linker histone H1 and H5 family EthD PF07110.11 KLO18807.1 - 0.096 13.8 1.6 0.28 12.4 0.0 2.5 2 1 0 2 2 2 0 EthD domain 2OG-FeII_Oxy_3 PF13640.6 KLO18808.1 - 1.7e-08 35.2 0.1 3.6e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YusW PF14039.6 KLO18808.1 - 0.094 13.2 0.2 0.25 11.9 0.2 1.7 1 0 0 1 1 1 0 YusW-like protein 2OG-FeII_Oxy_3 PF13640.6 KLO18809.1 - 3e-14 53.7 0.4 3.1e-08 34.4 0.0 2.9 3 0 0 3 3 3 2 2OG-Fe(II) oxygenase superfamily HEAT_2 PF13646.6 KLO18809.1 - 0.0051 17.2 0.0 1 9.8 0.0 3.2 2 0 0 2 2 2 1 HEAT repeats 2OG-FeII_Oxy_3 PF13640.6 KLO18810.1 - 1.4e-08 35.5 0.0 2.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Carot_N PF09150.10 KLO18811.1 - 0.038 13.9 0.3 0.089 12.7 0.3 1.6 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal p450 PF00067.22 KLO18812.1 - 1.3e-59 202.1 0.0 1.6e-59 201.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PsbM PF05151.12 KLO18812.1 - 0.23 11.3 0.9 0.82 9.5 0.9 1.9 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) Sarcoglycan_1 PF04790.13 KLO18813.1 - 0.12 11.7 6.3 0.18 11.1 0.0 2.9 3 0 0 3 3 3 0 Sarcoglycan complex subunit protein FAD_binding_2 PF00890.24 KLO18815.1 - 1.9e-126 422.5 3.0 2.4e-126 422.2 3.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KLO18815.1 - 1.5e-43 147.8 0.3 2.4e-43 147.2 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KLO18815.1 - 5.8e-06 25.7 1.8 0.00057 19.2 0.8 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO18815.1 - 8.9e-06 25.1 0.2 0.0038 16.5 0.0 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KLO18815.1 - 1.1e-05 24.7 2.1 0.0058 15.8 2.6 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KLO18815.1 - 0.0015 17.8 0.3 0.0029 16.9 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KLO18815.1 - 0.03 13.4 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KLO18815.1 - 0.048 12.4 1.4 0.18 10.5 0.7 2.2 4 0 0 4 4 4 0 HI0933-like protein DAO PF01266.24 KLO18815.1 - 0.14 11.7 1.6 0.42 10.1 1.5 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KLO18815.1 - 0.64 9.2 5.0 2.1 7.5 1.9 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RabGAP-TBC PF00566.18 KLO18816.1 - 3.1e-30 105.5 0.2 8.9e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain UCH_1 PF13423.6 KLO18817.1 - 4.7e-76 256.4 0.0 6.2e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KLO18817.1 - 5.3e-16 59.6 0.0 8.4e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 KLO18817.1 - 2.4e-05 23.9 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FeS_assembly_P PF01883.19 KLO18818.1 - 1.2e-12 47.8 0.0 2.3e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein FolB PF02152.18 KLO18818.1 - 0.062 13.9 0.0 3.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Dihydroneopterin aldolase Cullin_binding PF03556.15 KLO18819.1 - 2.1e-25 89.5 0.0 3.6e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Cullin binding DUF3408 PF11888.8 KLO18819.1 - 0.81 9.8 3.5 2.1 8.5 3.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) HTH_18 PF12833.7 KLO18820.1 - 0.026 14.8 2.8 0.078 13.3 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain WD40 PF00400.32 KLO18821.1 - 7.4e-71 232.3 33.7 3.4e-11 43.5 0.3 14.1 14 0 0 14 14 14 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO18821.1 - 1.2e-30 105.6 0.0 0.0022 18.3 0.0 10.0 3 2 7 11 11 10 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO18821.1 - 2.2e-17 63.0 0.5 0.078 11.9 0.0 8.4 3 3 4 8 8 8 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KLO18821.1 - 2.3e-09 36.9 2.6 0.96 9.5 0.0 8.3 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat NACHT PF05729.12 KLO18821.1 - 8.2e-09 35.6 0.0 1.9e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.11 KLO18821.1 - 4.8e-08 33.1 0.0 0.0033 17.3 0.0 3.8 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.6 KLO18821.1 - 6.9e-06 26.5 0.0 2.4e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain WD40_like PF17005.5 KLO18821.1 - 9.6e-06 25.1 0.0 0.11 11.8 0.0 3.5 4 1 0 4 4 4 2 WD40-like domain AAA PF00004.29 KLO18821.1 - 7.1e-05 23.2 0.0 0.00048 20.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KLO18821.1 - 0.00012 21.4 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Nup160 PF11715.8 KLO18821.1 - 0.00013 20.8 0.3 0.43 9.1 0.2 3.5 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KLO18821.1 - 0.00022 20.6 1.4 3.9 6.7 0.0 4.5 3 1 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal AAA_22 PF13401.6 KLO18821.1 - 0.00029 21.1 0.0 0.00081 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KLO18821.1 - 0.00063 19.0 0.0 0.0016 17.7 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 KLO18821.1 - 0.012 15.8 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain VID27 PF08553.10 KLO18821.1 - 0.014 14.5 0.5 1.4 7.9 0.1 3.3 4 0 0 4 4 4 0 VID27 C-terminal WD40-like domain Viral_helicase1 PF01443.18 KLO18821.1 - 0.017 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 KLO18821.1 - 0.018 14.3 0.9 0.28 10.4 0.2 2.3 1 1 0 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.20 KLO18821.1 - 0.043 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.27 KLO18821.1 - 0.049 14.2 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 KLO18821.1 - 0.061 13.7 0.0 0.27 11.6 0.0 2.2 2 0 0 2 2 1 0 RNA helicase cobW PF02492.19 KLO18821.1 - 0.071 12.7 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 KLO18821.1 - 0.077 13.0 0.1 1.4 8.9 0.0 2.8 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.6 KLO18821.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KLO18821.1 - 0.15 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 KLO18821.1 - 0.15 12.1 0.0 0.97 9.5 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase ResIII PF04851.15 KLO18821.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_C2 PF00648.21 KLO18822.1 - 1.5e-68 231.0 0.9 9.4e-68 228.4 0.9 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease ZZ PF00569.17 KLO18823.1 - 1.2e-13 50.7 5.8 2.1e-13 49.8 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UBR PF02207.20 KLO18823.1 - 0.024 14.8 3.3 0.045 13.9 3.3 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) MSA-2c PF12238.8 KLO18823.1 - 9.9 6.1 7.4 16 5.4 7.4 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c RdRP PF05183.12 KLO18824.1 - 2.2e-116 389.8 0.0 2.9e-116 389.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase G-patch PF01585.23 KLO18825.1 - 4.3e-05 23.3 3.4 0.00013 21.8 3.4 1.9 1 0 0 1 1 1 1 G-patch domain MRP-L27 PF09809.9 KLO18826.1 - 5.8e-07 29.3 0.1 7.8e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Ribo_biogen_C PF04034.13 KLO18827.1 - 1.5e-51 173.4 0.1 2e-51 173.0 0.1 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KLO18827.1 - 3.4e-14 52.4 0.1 5.6e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI FoP_duplication PF13865.6 KLO18827.1 - 8 7.1 9.1 4.8 7.8 3.8 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Cupin_8 PF13621.6 KLO18828.1 - 1.5e-31 110.1 0.1 2e-31 109.6 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KLO18828.1 - 7e-08 32.3 0.1 9.4e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KLO18828.1 - 0.00023 21.6 0.1 0.058 13.8 0.0 2.9 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KLO18828.1 - 0.01 15.6 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Cupin_1 PF00190.22 KLO18828.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 Cupin DUF3535 PF12054.8 KLO18829.1 - 4.2e-98 329.5 0.0 8e-96 321.9 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KLO18829.1 - 4.9e-68 229.4 0.0 1e-67 228.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO18829.1 - 5.6e-17 62.1 0.0 1.3e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KLO18829.1 - 1.5e-11 43.5 10.6 1.7 9.1 0.0 9.6 8 0 0 8 8 8 3 HEAT repeat TAF6_C PF07571.13 KLO18829.1 - 0.00091 19.5 0.1 0.11 12.8 0.0 3.9 4 0 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 KLO18829.1 - 0.0025 18.4 0.0 4.3 8.0 0.0 3.0 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KLO18829.1 - 0.0026 18.2 14.3 18 6.0 0.0 8.5 9 1 0 9 9 9 0 HEAT-like repeat DUF3385 PF11865.8 KLO18829.1 - 0.0053 16.7 0.2 0.02 14.8 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 KLO18829.1 - 0.017 15.5 5.9 40 4.7 0.0 6.0 7 1 0 7 7 7 0 HEAT repeats ERCC3_RAD25_C PF16203.5 KLO18829.1 - 0.078 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Amnionless PF14828.6 KLO18830.1 - 0.00075 18.5 0.1 0.00092 18.2 0.1 1.3 1 0 0 1 1 1 1 Amnionless DUF2141 PF09912.9 KLO18830.1 - 0.0067 16.3 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2141) DUF456 PF04306.13 KLO18830.1 - 0.022 15.0 0.8 0.044 14.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF4064 PF13273.6 KLO18830.1 - 0.059 13.6 1.5 0.18 12.1 1.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Glycophorin_A PF01102.18 KLO18830.1 - 0.069 13.4 0.0 0.069 13.4 0.0 2.6 2 1 0 2 2 2 0 Glycophorin A DUF2407_C PF13373.6 KLO18830.1 - 0.087 13.0 0.0 0.37 11.0 0.0 1.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain Gly-zipper_OmpA PF13436.6 KLO18830.1 - 1.3 8.9 4.5 2.6 7.9 4.5 1.5 1 0 0 1 1 1 0 Glycine-zipper domain Peptidase_M76 PF09768.9 KLO18831.1 - 0.14 11.9 2.8 1.1 9.0 1.5 2.3 2 0 0 2 2 2 0 Peptidase M76 family RsfS PF02410.15 KLO18833.1 - 1.4e-05 25.4 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation SHR3_chaperone PF08229.11 KLO18834.1 - 1.2e-38 132.0 0.0 1.7e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.6 KLO18834.1 - 0.11 13.0 1.0 0.64 10.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) EI24 PF07264.11 KLO18835.1 - 2.8e-34 118.9 11.6 4.5e-34 118.2 11.6 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) tRNA_int_endo PF01974.17 KLO18836.1 - 1.5e-14 53.8 0.0 2.9e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain RAP1 PF07218.11 KLO18836.1 - 0.037 12.3 2.5 0.046 12.0 2.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Lipase_GDSL_2 PF13472.6 KLO18837.1 - 6.8e-29 101.5 0.0 1.1e-28 100.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KLO18837.1 - 7.3e-16 58.7 0.0 1.1e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rhodanese PF00581.20 KLO18838.1 - 1.6e-12 47.9 0.0 3.5e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Helicase_C PF00271.31 KLO18839.1 - 1.1e-14 54.7 0.8 6.2e-14 52.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO18839.1 - 9.6e-11 41.8 0.0 2.1e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KLO18839.1 - 0.00066 20.3 1.0 0.0019 18.9 1.0 1.8 1 0 0 1 1 1 1 RecQ zinc-binding 2Fe-2S_thioredx PF01257.19 KLO18840.1 - 1.8e-58 196.5 0.0 2.2e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Bestrophin PF01062.21 KLO18841.1 - 9.2e-41 140.2 0.0 6.7e-40 137.3 0.0 1.9 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel GCIP PF13324.6 KLO18842.1 - 1.5e-37 129.6 1.2 2.3e-37 129.1 1.2 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting ER PF01133.17 KLO18842.1 - 0.038 14.0 0.0 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 Enhancer of rudimentary DEAD_2 PF06733.15 KLO18845.1 - 2.7e-49 167.1 0.0 5.5e-49 166.2 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KLO18845.1 - 9.4e-49 165.7 7.9 1.6e-44 151.9 0.7 2.9 3 0 0 3 3 3 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KLO18845.1 - 5.1e-44 150.4 0.0 1e-43 149.4 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KLO18845.1 - 5.4e-05 23.3 0.1 0.0029 17.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KLO18845.1 - 0.01 15.6 0.2 0.59 9.9 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase Exog_C PF18026.1 KLO18845.1 - 0.092 12.8 0.5 1.3 9.1 0.1 2.6 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain FBA_3 PF08268.12 KLO18845.1 - 0.13 12.2 0.2 0.42 10.6 0.1 1.8 2 0 0 2 2 2 0 F-box associated domain E1_dh PF00676.20 KLO18846.1 - 4.4e-116 387.0 0.0 5.3e-116 386.8 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KLO18846.1 - 5.6e-05 22.5 0.0 0.00012 21.4 0.0 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KLO18846.1 - 0.0036 17.1 2.2 0.0072 16.1 0.6 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4873 PF16170.5 KLO18846.1 - 0.089 13.0 0.1 0.27 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4873) DUF1713 PF08213.11 KLO18847.1 - 8.8e-09 35.1 22.4 1.2e-08 34.7 22.4 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Ribosomal_L21p PF00829.21 KLO18847.1 - 0.1 12.8 0.6 0.19 12.0 0.6 1.3 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein BLM10_mid PF16507.5 KLO18849.1 - 2.4e-107 359.8 8.3 2e-104 350.1 8.3 2.7 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KLO18849.1 - 1.6e-22 79.2 0.1 1.1e-21 76.5 0.1 2.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KLO18849.1 - 0.016 15.4 0.0 16 6.1 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat BLM10_N PF16547.5 KLO18849.1 - 0.021 15.1 0.0 0.063 13.6 0.0 1.8 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal HEAT_2 PF13646.6 KLO18849.1 - 0.021 15.2 0.0 9.3 6.7 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats KDZ PF18758.1 KLO18850.1 - 3.5e-53 180.5 0.1 6.4e-53 179.6 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KLO18850.1 - 8.1e-33 112.8 0.1 1.8e-32 111.7 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF2213 PF09979.9 KLO18850.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) CxC1 PF18802.1 KLO18850.1 - 0.065 13.4 0.0 0.36 11.0 0.0 2.3 2 0 0 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases DUF4484 PF14831.6 KLO18854.1 - 0.08 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) TPR_2 PF07719.17 KLO18855.1 - 0.65 10.2 3.3 32 5.0 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Cellulase PF00150.18 KLO18856.1 - 3.1e-15 56.4 0.5 3.1e-15 56.4 0.5 2.3 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KLO18856.1 - 1e-05 25.3 0.0 0.029 14.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 KLO18856.1 - 0.02 14.0 0.1 0.039 13.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KLO18856.1 - 0.14 11.5 3.7 0.75 9.1 0.1 2.4 3 0 0 3 3 3 0 Beta-galactosidase PUF PF00806.19 KLO18862.1 - 3.9e-19 67.2 0.0 0.00011 21.6 0.1 6.2 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat COG6 PF06419.11 KLO18863.1 - 3.3e-156 521.1 0.1 4.4e-156 520.7 0.1 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 T3SSipB PF16535.5 KLO18863.1 - 0.0063 17.0 1.6 0.065 13.7 0.5 2.6 2 0 0 2 2 2 1 Type III cell invasion protein SipB Laminin_II PF06009.12 KLO18863.1 - 0.0082 16.2 1.9 0.019 15.0 0.2 2.5 3 0 0 3 3 3 1 Laminin Domain II Jnk-SapK_ap_N PF09744.9 KLO18863.1 - 0.011 16.0 2.2 0.035 14.3 2.2 1.9 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 MscS_porin PF12795.7 KLO18863.1 - 0.015 14.8 1.5 0.047 13.2 1.5 1.8 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Dor1 PF04124.12 KLO18863.1 - 0.042 12.5 0.6 0.15 10.7 0.2 2.0 2 0 0 2 2 2 0 Dor1-like family DUF1664 PF07889.12 KLO18863.1 - 0.048 13.7 0.5 0.16 12.0 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KLO18863.1 - 0.052 14.0 0.3 0.96 10.0 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 KLO18863.1 - 0.68 10.3 4.8 0.43 11.0 1.6 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Aldolase_II PF00596.21 KLO18864.1 - 2.1e-44 151.7 0.0 2.7e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1645 PF07816.11 KLO18867.1 - 5.6 7.5 11.9 2.8 8.5 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) MIF PF01187.18 KLO18868.1 - 5.9e-13 49.1 0.0 6.7e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 KLO18868.1 - 0.036 14.0 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Tautomerase enzyme MIF PF01187.18 KLO18869.1 - 1.6e-16 60.6 0.0 1.8e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MIF PF01187.18 KLO18870.1 - 2.2e-21 76.3 0.0 2.5e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 KLO18870.1 - 1.7e-05 24.6 0.1 0.1 12.5 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme Proton_antipo_N PF00662.20 KLO18871.1 - 1 9.5 5.7 4.4 7.4 0.1 3.1 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DSPc PF00782.20 KLO18872.1 - 1e-28 99.8 0.0 1.2e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KLO18872.1 - 0.00018 21.2 0.1 0.00023 20.8 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KLO18872.1 - 0.0073 16.6 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain CDKN3 PF05706.12 KLO18872.1 - 0.068 12.8 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Pro-kuma_activ PF09286.11 KLO18874.1 - 2.1e-36 125.4 0.0 3.5e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KLO18874.1 - 0.00025 20.4 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family eRF1_2 PF03464.15 KLO18875.1 - 8.4e-47 158.8 0.0 1.6e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KLO18875.1 - 9.8e-39 132.3 0.1 1.9e-38 131.4 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KLO18875.1 - 2.2e-19 69.7 0.0 4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KLO18875.1 - 6.3e-09 36.2 0.1 9.9e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KLO18875.1 - 6e-08 33.0 0.0 9.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 MFS_1 PF07690.16 KLO18876.1 - 1.5e-38 132.6 64.8 1.6e-38 132.5 59.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KLO18876.1 - 2.5e-16 59.3 11.2 2.5e-16 59.3 11.2 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 KLO18876.1 - 0.15 12.6 2.9 0.54 10.8 2.9 2.0 1 0 0 1 1 1 0 Phage holin family 2 OATP PF03137.20 KLO18876.1 - 5.7 5.1 17.6 0.06 11.6 4.3 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Plus-3 PF03126.18 KLO18877.1 - 2.1e-27 95.8 0.0 1.7e-26 92.9 0.0 2.4 2 0 0 2 2 2 1 Plus-3 domain RNA_pol_Rpc34 PF05158.12 KLO18878.1 - 6.7e-76 255.8 5.3 2.1e-75 254.2 5.3 1.7 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit Presenilin PF01080.17 KLO18878.1 - 0.015 14.1 5.7 0.021 13.6 5.7 1.2 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 KLO18878.1 - 0.19 10.5 4.5 0.3 9.9 4.5 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4604 PF15377.6 KLO18878.1 - 0.24 11.8 20.6 0.49 10.8 20.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RPA_C PF08784.11 KLO18878.1 - 0.24 12.1 1.4 0.42 11.3 0.1 2.2 2 0 0 2 2 2 0 Replication protein A C terminal DUF3504 PF12012.8 KLO18878.1 - 0.37 10.7 0.0 0.37 10.7 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3504) CCDC53 PF10152.9 KLO18878.1 - 0.89 10.0 6.8 2 8.8 6.8 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Zip PF02535.22 KLO18878.1 - 2.9 7.0 5.4 4.8 6.3 5.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 KLO18878.1 - 3.9 7.2 11.0 7.5 6.3 11.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 KLO18878.1 - 4.1 6.7 10.6 6.4 6.1 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Vfa1 PF08432.10 KLO18878.1 - 6.7 7.0 16.2 15 5.8 16.2 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BPL_N PF09825.9 KLO18879.1 - 3.7e-108 362.0 0.0 4.5e-108 361.7 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KLO18879.1 - 7e-25 87.4 0.0 1.4e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KLO18879.1 - 0.0022 17.9 0.0 0.0083 16.0 0.0 2.0 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain GATase_3 PF07685.14 KLO18879.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain AAA_11 PF13086.6 KLO18880.1 - 1e-65 222.2 0.8 1.9e-65 221.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KLO18880.1 - 7.4e-59 198.7 0.0 1.3e-58 197.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KLO18880.1 - 1.1e-10 41.7 0.5 0.015 15.1 0.0 3.8 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KLO18880.1 - 2.1e-10 40.6 0.0 5.3e-07 29.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KLO18880.1 - 1.5e-07 31.9 0.0 8.7e-07 29.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KLO18880.1 - 5.9e-06 25.8 0.6 0.13 11.4 0.0 3.6 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KLO18880.1 - 7e-05 22.9 0.0 0.0012 18.9 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 KLO18880.1 - 0.00088 19.1 0.0 0.0033 17.2 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DEAD PF00270.29 KLO18880.1 - 0.0026 17.5 0.2 0.059 13.1 0.2 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 KLO18880.1 - 0.0054 16.2 0.0 0.8 9.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.6 KLO18880.1 - 0.01 15.5 0.0 0.96 9.1 0.0 3.0 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.6 KLO18880.1 - 0.011 16.0 0.5 0.1 12.9 0.5 2.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KLO18880.1 - 0.017 15.5 0.1 0.044 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KLO18880.1 - 0.024 15.1 2.0 0.31 11.5 0.2 3.1 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 KLO18880.1 - 0.025 14.4 0.1 3.2 7.6 0.0 3.3 3 0 0 3 3 3 0 Helicase UvrD-helicase PF00580.21 KLO18880.1 - 0.041 13.4 0.1 0.19 11.2 0.1 2.1 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KLO18880.1 - 0.049 13.0 0.2 1.4 8.2 0.1 2.4 1 1 0 2 2 2 0 UvrD-like helicase C-terminal domain zf-primase PF09329.11 KLO18881.1 - 0.081 12.8 0.6 0.15 11.9 0.6 1.4 1 0 0 1 1 1 0 Primase zinc finger DNA_pol_B_thumb PF14791.6 KLO18882.1 - 1.2e-19 70.2 0.0 2.5e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KLO18882.1 - 2.7e-15 56.6 0.0 4.9e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KLO18882.1 - 4e-12 46.3 0.0 1.1e-10 41.7 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KLO18882.1 - 9.8e-08 31.7 0.0 2.3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 KLO18882.1 - 0.00029 21.4 0.0 0.012 16.2 0.0 3.1 3 0 0 3 3 3 1 Helix-hairpin-helix domain Cdd1 PF11731.8 KLO18882.1 - 0.0012 19.0 0.0 0.006 16.8 0.0 2.1 2 0 0 2 2 2 1 Pathogenicity locus HHH PF00633.23 KLO18882.1 - 0.024 14.5 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif IMS_HHH PF11798.8 KLO18882.1 - 0.13 12.6 0.0 2 8.9 0.0 2.5 2 0 0 2 2 2 0 IMS family HHH motif TRAP_alpha PF03896.16 KLO18883.1 - 0.039 13.2 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit InaF-motif PF15018.6 KLO18884.1 - 0.0028 17.5 14.2 0.018 14.9 0.2 4.0 3 0 0 3 3 3 2 TRP-interacting helix DUF2738 PF10927.8 KLO18884.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Helitron_like_N PF14214.6 KLO18886.1 - 2.9e-19 70.0 0.0 3.8e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus CobA_CobO_BtuR PF02572.15 KLO18887.1 - 0.017 15.4 0.0 0.02 15.2 0.0 1.2 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP LRR_4 PF12799.7 KLO18888.1 - 2e-05 24.8 0.9 0.0032 17.9 0.0 3.7 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) CxC2 PF18803.1 KLO18890.1 - 5.5e-05 23.3 0.0 0.00015 21.9 0.0 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KLO18894.1 - 2.4e-17 63.0 0.0 3.3e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases ox_reductase_C PF08635.10 KLO18898.1 - 1.1e-55 187.2 0.1 1.8e-55 186.5 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 KLO18898.1 - 2.6e-12 47.6 0.0 4.8e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Arabinose_trans PF04602.12 KLO18898.1 - 0.012 14.5 0.2 0.018 13.9 0.2 1.2 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein HEAT_2 PF13646.6 KLO18899.1 - 1.2e-06 28.8 9.4 0.4 11.1 0.1 7.4 5 2 2 7 7 7 2 HEAT repeats HEAT_EZ PF13513.6 KLO18899.1 - 0.00031 21.2 18.9 0.029 14.9 0.2 8.0 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.22 KLO18899.1 - 0.00045 20.2 23.8 0.21 11.9 0.0 9.8 12 0 0 12 12 12 3 HEAT repeat Adaptin_N PF01602.20 KLO18899.1 - 0.02 13.5 0.8 0.39 9.2 0.0 3.4 3 1 1 4 4 4 0 Adaptin N terminal region Arm PF00514.23 KLO18899.1 - 0.022 14.8 2.8 0.3 11.2 0.4 4.1 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat F_actin_bind PF08919.10 KLO18899.1 - 0.03 14.4 0.0 6.8 6.8 0.0 4.0 3 0 0 3 3 3 0 F-actin binding Sld5 PF05916.11 KLO18901.1 - 0.0032 17.9 0.0 0.0052 17.2 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Zn_clus PF00172.18 KLO18902.1 - 2.8e-05 24.1 9.3 5.1e-05 23.3 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF104 PF01954.16 KLO18902.1 - 0.18 12.3 0.1 0.32 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF104 Glyco_hydro_1 PF00232.18 KLO18904.1 - 8.4e-155 515.6 0.5 1.1e-154 515.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 GFO_IDH_MocA PF01408.22 KLO18905.1 - 3.7e-14 53.6 0.0 7.2e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KLO18905.1 - 0.00036 20.5 0.0 0.00065 19.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Peroxin-3 PF04882.12 KLO18906.1 - 6.3e-120 401.3 0.8 7.6e-120 401.1 0.8 1.1 1 0 0 1 1 1 1 Peroxin-3 PH_6 PF15406.6 KLO18906.1 - 0.086 13.1 0.2 0.16 12.2 0.2 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain AAA_5 PF07728.14 KLO18907.1 - 1.5e-60 203.2 0.0 1.2e-28 99.9 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) GNVR PF13807.6 KLO18907.1 - 0.0021 17.9 0.0 0.0058 16.5 0.0 1.7 1 0 0 1 1 1 1 G-rich domain on putative tyrosine kinase vWA-TerF-like PF10138.9 KLO18907.1 - 0.0038 17.4 0.1 0.0078 16.3 0.1 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus AAA_16 PF13191.6 KLO18907.1 - 0.012 16.0 0.8 15 5.9 0.0 4.1 3 1 1 4 4 4 0 AAA ATPase domain AAA_lid_7 PF17867.1 KLO18907.1 - 0.14 12.3 0.0 4.1 7.7 0.0 2.7 2 0 0 2 2 2 0 Midasin AAA lid domain Sds3 PF08598.11 KLO18908.1 - 6.6e-19 68.8 8.9 3.3e-18 66.5 5.8 2.4 2 0 0 2 2 2 1 Sds3-like Nop14 PF04147.12 KLO18908.1 - 2.4 6.3 25.3 6.7 4.8 25.3 1.7 1 0 0 1 1 1 0 Nop14-like family Far-17a_AIG1 PF04750.14 KLO18909.1 - 6.1e-25 87.7 3.9 7.7e-25 87.4 3.9 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Vps26 PF03643.15 KLO18910.1 - 3.8e-129 429.5 3.6 4.3e-129 429.4 3.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 p450 PF00067.22 KLO18912.1 - 1.8e-58 198.4 0.0 2.8e-57 194.5 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_A22B PF04258.13 KLO18913.1 - 0.089 12.3 0.1 0.089 12.3 0.1 2.5 2 0 0 2 2 2 0 Signal peptide peptidase DUF1761 PF08570.10 KLO18913.1 - 2.4 8.5 9.7 0.13 12.5 1.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1761) Zn_clus PF00172.18 KLO18917.1 - 0.00027 21.0 8.0 0.0004 20.4 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLA2_B PF01735.18 KLO18918.1 - 2.5e-80 270.3 13.6 2.8e-76 256.9 13.6 3.2 1 1 0 1 1 1 1 Lysophospholipase catalytic domain AMP-binding PF00501.28 KLO18919.1 - 3.1e-30 105.1 0.0 1.7e-29 102.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Iron_traffic PF04362.14 KLO18920.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Ribosomal_L7Ae PF01248.26 KLO18921.1 - 1.3e-21 76.2 0.3 2.6e-21 75.2 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family GTP-bdg_N PF13167.6 KLO18921.1 - 0.11 13.1 0.0 0.43 11.3 0.1 1.9 2 0 0 2 2 2 0 GTP-binding GTPase N-terminal Methyltransf_16 PF10294.9 KLO18922.1 - 7.7e-20 71.3 0.0 9.6e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 KLO18922.1 - 0.0005 19.4 0.0 0.00071 18.9 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PrmA PF06325.13 KLO18922.1 - 0.06 12.7 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) zinc_ribbon_9 PF14369.6 KLO18923.1 - 0.079 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon PI-PLC-X PF00388.19 KLO18924.1 - 8.6e-52 174.6 0.0 1.7e-51 173.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KLO18924.1 - 2.5e-42 143.8 0.3 7e-42 142.4 0.3 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KLO18924.1 - 1.3e-11 44.7 0.0 9.1e-10 38.8 0.0 2.6 1 1 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 KLO18924.1 - 5.6e-06 26.7 3.4 0.0001 22.7 1.5 3.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KLO18924.1 - 0.0037 16.7 0.1 0.012 15.1 0.1 2.0 1 0 0 1 1 1 1 EF hand EF-hand_like PF09279.11 KLO18924.1 - 0.018 15.5 0.9 0.071 13.6 0.2 2.4 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.6 KLO18924.1 - 0.062 13.2 1.0 3.1 7.7 0.4 3.2 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 KLO18924.1 - 0.12 12.4 1.7 1 9.4 0.0 3.2 4 0 0 4 4 4 0 EF-hand domain PLA2_B PF01735.18 KLO18926.1 - 2.8e-71 240.4 12.9 9.9e-69 232.0 12.9 3.1 1 1 0 1 1 1 1 Lysophospholipase catalytic domain CDP-OH_P_transf PF01066.21 KLO18926.1 - 0.03 15.1 0.0 0.13 13.1 0.0 2.1 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase IBR PF01485.21 KLO18926.1 - 1 9.6 3.3 0.49 10.7 1.1 1.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Spt5-NGN PF03439.13 KLO18930.1 - 4.6e-23 80.9 0.0 9.3e-23 79.9 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KLO18930.1 - 1.5e-16 61.2 11.1 1.5e-16 61.2 11.1 3.6 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KLO18930.1 - 2.4e-10 40.0 18.8 0.00016 21.5 0.1 6.9 7 0 0 7 7 7 4 KOW motif CTD PF12815.7 KLO18930.1 - 0.00019 21.9 16.6 0.00019 21.9 16.6 4.0 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF3912 PF13051.6 KLO18930.1 - 0.031 14.5 0.1 0.1 12.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) Cellulase PF00150.18 KLO18932.1 - 2e-08 34.0 0.0 6.5e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 KLO18933.1 - 7.8e-09 35.4 0.3 1.4e-07 31.2 0.3 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Env-gp36 PF09590.10 KLO18933.1 - 0.11 10.9 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein AAA_16 PF13191.6 KLO18934.1 - 0.045 14.1 0.3 0.12 12.8 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 KLO18934.1 - 0.047 13.1 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Pkinase PF00069.25 KLO18937.1 - 1.6e-74 250.6 0.0 2.6e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO18937.1 - 3.5e-32 111.7 0.0 6.2e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO18937.1 - 1e-06 28.3 0.0 1.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO18937.1 - 2.7e-05 23.2 0.0 7.2e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO18937.1 - 0.0013 18.1 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO18937.1 - 0.022 14.7 0.0 0.13 12.2 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KLO18937.1 - 0.062 12.8 0.3 0.25 10.9 0.0 2.1 2 1 1 3 3 3 0 PhoP regulatory network protein YrbL AviRa PF11599.8 KLO18937.1 - 0.1 12.1 0.2 0.18 11.2 0.2 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa ER-remodelling PF14755.6 KLO18937.1 - 3.5 7.9 8.3 0.44 10.8 3.9 1.7 2 0 0 2 2 2 0 Intracellular membrane remodeller DUF2013 PF09431.10 KLO18938.1 - 9.9e-55 184.5 1.8 9.9e-55 184.5 1.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) RYDR_ITPR PF01365.21 KLO18938.1 - 0.063 12.7 0.7 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 RIH domain SDP_N PF12278.8 KLO18938.1 - 7.4 6.7 9.1 26 5.0 9.1 1.9 1 0 0 1 1 1 0 Sex determination protein N terminal ATP-synt PF00231.19 KLO18939.1 - 1.9e-82 277.2 1.5 2.2e-82 276.9 1.5 1.0 1 0 0 1 1 1 1 ATP synthase NAD_Gly3P_dh_C PF07479.14 KLO18939.1 - 0.068 13.4 0.3 0.3 11.4 0.0 2.3 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus eIF-5_eIF-2B PF01873.17 KLO18940.1 - 3.1e-37 127.0 0.4 5.7e-37 126.2 0.4 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Arc_trans_TRASH PF08394.10 KLO18940.1 - 0.13 12.7 0.7 0.13 12.7 0.7 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain Cna_B PF05738.13 KLO18940.1 - 0.16 12.5 1.7 0.46 11.1 0.6 2.1 1 1 1 2 2 2 0 Cna protein B-type domain WD40 PF00400.32 KLO18941.1 - 1.9e-25 88.6 0.7 0.00015 22.5 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO18941.1 - 1e-13 51.4 0.0 1.8e-05 24.9 0.0 4.9 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO18941.1 - 7.8e-05 22.6 0.0 0.15 11.9 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KLO18941.1 - 0.043 13.8 2.3 18 5.4 0.0 5.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat UPF0029 PF01205.19 KLO18942.1 - 2.6e-24 85.6 0.1 5.2e-24 84.6 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 PHM7_cyt PF14703.6 KLO18942.1 - 0.068 13.4 1.4 3.9 7.7 0.1 2.4 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Nup54 PF13874.6 KLO18943.1 - 7.6e-37 126.5 1.6 7.6e-37 126.5 1.6 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KLO18943.1 - 1.6e-10 41.7 94.1 0.00074 20.3 18.6 5.0 1 1 2 3 3 3 3 Nucleoporin FG repeat region Nup54_C PF18437.1 KLO18943.1 - 0.006 16.5 4.0 0.006 16.5 4.0 2.4 2 0 0 2 2 2 1 Nup54 C-terminal interacting domain Sec2p PF06428.11 KLO18943.1 - 0.097 12.7 2.6 0.74 9.8 0.2 2.8 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p Mustang PF15682.5 KLO18943.1 - 0.15 12.1 1.4 14 5.8 0.2 3.1 2 0 0 2 2 2 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 FUSC PF04632.12 KLO18943.1 - 0.85 8.1 4.3 1.4 7.4 4.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family SlyX PF04102.12 KLO18943.1 - 1.7 9.3 17.5 13 6.4 0.6 4.4 3 1 1 4 4 4 0 SlyX ABC_tran PF00005.27 KLO18944.1 - 1.9e-47 161.2 0.8 8.1e-28 97.6 0.0 3.3 3 1 1 4 4 3 2 ABC transporter ABC_membrane PF00664.23 KLO18944.1 - 1.6e-35 123.1 22.5 7.8e-18 65.1 3.2 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KLO18944.1 - 3.5e-12 46.3 0.0 0.0005 19.6 0.0 3.6 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KLO18944.1 - 6.5e-07 29.5 3.4 0.19 11.5 0.1 4.4 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KLO18944.1 - 3.4e-06 27.5 0.1 0.16 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KLO18944.1 - 1.8e-05 25.3 8.7 0.00083 19.9 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 KLO18944.1 - 0.00021 20.9 0.1 0.48 10.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KLO18944.1 - 0.00026 20.1 0.0 0.48 9.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 KLO18944.1 - 0.00061 19.3 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KLO18944.1 - 0.0014 18.7 0.1 0.28 11.3 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KLO18944.1 - 0.0015 18.1 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KLO18944.1 - 0.0017 18.1 0.8 1.2 8.8 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 KLO18944.1 - 0.0031 17.8 0.2 5.2 7.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KLO18944.1 - 0.0051 16.6 0.0 0.14 11.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KLO18944.1 - 0.0051 16.7 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KLO18944.1 - 0.0062 17.1 0.1 2.2 8.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 KLO18944.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 KLO18944.1 - 0.016 15.2 0.0 12 5.8 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 KLO18944.1 - 0.016 15.2 0.6 8 6.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KLO18944.1 - 0.024 13.8 1.0 3 7.0 0.0 3.0 2 1 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 KLO18944.1 - 0.026 14.9 0.0 4.9 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KLO18944.1 - 0.041 13.2 0.1 9.1 5.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KLO18944.1 - 0.05 12.9 0.0 11 5.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 KLO18944.1 - 0.056 13.5 0.2 0.72 9.9 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 KLO18944.1 - 0.058 13.1 2.9 14 5.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 KLO18944.1 - 0.078 13.4 4.1 0.22 11.9 0.2 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KLO18944.1 - 0.13 12.1 1.3 1.7 8.4 0.4 2.8 2 1 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 KLO18944.1 - 0.13 11.1 0.0 0.31 9.8 0.0 1.6 1 0 0 1 1 1 0 Adenovirus IVa2 protein TrwB_AAD_bind PF10412.9 KLO18944.1 - 0.13 11.2 0.3 2 7.2 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 KLO18945.1 - 1.2e-47 161.8 0.2 7.4e-29 101.0 0.1 3.1 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 KLO18945.1 - 2.8e-32 112.5 23.1 1.3e-17 64.3 7.2 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KLO18945.1 - 8.5e-13 48.2 4.5 0.0066 15.9 0.2 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KLO18945.1 - 2e-07 31.1 6.8 0.022 14.6 0.3 4.4 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KLO18945.1 - 4.1e-06 26.0 0.0 0.069 12.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KLO18945.1 - 2e-05 24.2 0.6 0.3 10.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KLO18945.1 - 3e-05 24.5 0.2 0.35 11.2 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KLO18945.1 - 0.00015 21.6 0.3 1 9.1 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KLO18945.1 - 0.00015 21.7 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KLO18945.1 - 0.00019 21.5 1.0 0.042 13.9 0.2 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KLO18945.1 - 0.00022 20.9 0.0 0.89 9.1 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 KLO18945.1 - 0.00037 20.1 0.1 0.49 9.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 KLO18945.1 - 0.00042 20.9 0.0 0.00042 20.9 0.0 3.3 4 0 0 4 4 2 2 AAA domain ResIII PF04851.15 KLO18945.1 - 0.0013 18.7 0.1 1.8 8.6 0.0 3.0 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit AAA_15 PF13175.6 KLO18945.1 - 0.0015 18.3 2.6 0.022 14.5 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 KLO18945.1 - 0.0016 19.0 0.1 5 7.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KLO18945.1 - 0.002 17.9 3.3 0.8 9.4 0.0 3.4 4 0 0 4 4 4 2 AAA domain DUF87 PF01935.17 KLO18945.1 - 0.0038 17.4 0.8 0.15 12.2 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KLO18945.1 - 0.0042 17.3 0.3 7.6 6.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KLO18945.1 - 0.0048 16.3 0.0 0.69 9.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 KLO18945.1 - 0.0056 15.6 0.9 0.58 9.0 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 KLO18945.1 - 0.0086 16.1 0.7 11 6.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KLO18945.1 - 0.01 15.0 0.1 0.74 8.9 0.0 2.9 2 1 0 2 2 2 0 NB-ARC domain MeaB PF03308.16 KLO18945.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Pox_A32 PF04665.12 KLO18945.1 - 0.026 14.0 0.6 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.12 KLO18945.1 - 0.032 13.5 0.1 9.5 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DEAD PF00270.29 KLO18945.1 - 0.061 13.1 0.1 8 6.2 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase TsaE PF02367.17 KLO18945.1 - 0.061 13.3 0.1 17 5.4 0.0 3.2 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Adeno_IVa2 PF02456.15 KLO18945.1 - 0.082 11.7 0.1 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF2075 PF09848.9 KLO18945.1 - 0.089 12.0 0.9 12 5.0 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KLO18945.1 - 0.11 13.0 0.1 25 5.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase DUF5337 PF17272.2 KLO18945.1 - 0.15 11.9 2.8 0.27 11.1 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5337) AAA_33 PF13671.6 KLO18945.1 - 0.21 11.8 1.3 14 5.8 0.1 2.9 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 KLO18945.1 - 0.3 11.5 3.4 2.8 8.4 0.1 3.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KLO18945.1 - 0.39 10.3 2.7 0.93 9.0 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KLO18945.1 - 4.3 7.4 5.5 13 5.8 0.0 3.4 4 0 0 4 4 3 0 Dynamin family Abhydrolase_1 PF00561.20 KLO18946.1 - 6.1e-23 81.8 0.0 2.4e-21 76.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO18946.1 - 2.9e-10 41.1 0.0 3.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO18946.1 - 3.5e-10 39.5 0.0 3.6e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KLO18946.1 - 0.00091 18.9 0.0 0.0027 17.3 0.0 1.7 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 KLO18946.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Palm_thioest PF02089.15 KLO18946.1 - 0.16 11.8 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF1057 PF06342.12 KLO18946.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) AA_kinase PF00696.28 KLO18946.1 - 0.22 11.1 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Amino acid kinase family Abhydrolase_1 PF00561.20 KLO18947.1 - 2.9e-21 76.3 0.2 1.7e-20 73.8 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO18947.1 - 1.4e-13 52.0 0.7 1.9e-13 51.5 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO18947.1 - 5.5e-08 32.4 0.0 1.1e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KLO18947.1 - 0.00034 20.8 0.0 0.00051 20.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF915 PF06028.11 KLO18947.1 - 0.032 13.6 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S15 PF02129.18 KLO18947.1 - 0.061 12.9 0.1 0.52 9.9 0.1 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 KLO18947.1 - 0.18 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KLO18947.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF3328 PF11807.8 KLO18948.1 - 9.3e-20 71.3 1.0 2.1e-19 70.2 1.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Prefoldin PF02996.17 KLO18949.1 - 6.8e-29 100.2 1.7 8e-29 100.0 1.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KLO18949.1 - 0.0021 18.0 4.0 0.024 14.6 0.3 2.2 2 0 0 2 2 2 1 Prefoldin subunit Baculo_PEP_C PF04513.12 KLO18949.1 - 0.0031 17.6 1.5 0.24 11.5 0.1 2.1 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus EspB PF05802.11 KLO18949.1 - 0.022 14.8 0.6 0.022 14.8 0.6 1.9 2 0 0 2 2 2 0 Enterobacterial EspB protein COG2 PF06148.11 KLO18949.1 - 0.04 14.0 1.6 1.3 9.1 0.2 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PHM7_cyt PF14703.6 KLO18949.1 - 0.043 14.1 1.8 0.08 13.2 1.8 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF1664 PF07889.12 KLO18949.1 - 0.047 13.7 5.0 0.86 9.6 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) UPF0449 PF15136.6 KLO18949.1 - 0.086 13.3 3.4 6.6 7.3 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF4743 PF15916.5 KLO18950.1 - 3.1e-11 43.3 0.0 6.4e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KLO18950.1 - 1.3e-08 35.0 0.1 3.4e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain DUF3640 PF12342.8 KLO18950.1 - 0.07 12.9 0.1 0.07 12.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) ABC_tran PF00005.27 KLO18951.1 - 9.3e-44 149.3 0.1 1.8e-27 96.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KLO18951.1 - 7.8e-37 127.4 28.7 2.1e-19 70.2 13.1 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KLO18951.1 - 2.4e-12 46.8 1.2 8.3e-05 22.1 0.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KLO18951.1 - 1.8e-07 31.7 1.2 0.028 14.8 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KLO18951.1 - 3.4e-07 30.4 3.7 0.28 10.9 0.1 4.4 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KLO18951.1 - 7.5e-07 29.9 8.1 0.00078 20.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 KLO18951.1 - 1.6e-06 27.4 0.0 0.0063 15.6 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KLO18951.1 - 2.1e-06 27.4 0.5 0.097 12.4 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KLO18951.1 - 4.4e-05 23.3 0.2 0.15 11.8 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.6 KLO18951.1 - 8.9e-05 22.1 0.3 0.077 12.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KLO18951.1 - 0.00047 20.2 0.0 0.017 15.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KLO18951.1 - 0.00051 20.3 0.0 4.9 7.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KLO18951.1 - 0.001 19.6 0.0 0.67 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KLO18951.1 - 0.0011 19.1 1.0 0.031 14.4 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_7 PF12775.7 KLO18951.1 - 0.0017 17.9 0.1 2 7.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region NTPase_1 PF03266.15 KLO18951.1 - 0.002 18.0 2.1 0.28 11.1 0.1 3.4 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.9 KLO18951.1 - 0.0031 16.8 0.0 0.5 9.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KLO18951.1 - 0.0037 17.1 0.0 3.4 7.4 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KLO18951.1 - 0.0043 16.8 4.6 2.8 7.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KLO18951.1 - 0.0046 16.3 0.1 2.3 7.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family ResIII PF04851.15 KLO18951.1 - 0.0057 16.7 0.0 3.6 7.6 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 KLO18951.1 - 0.0068 16.3 0.0 0.49 10.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase TrwB_AAD_bind PF10412.9 KLO18951.1 - 0.0072 15.3 0.0 0.42 9.5 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 KLO18951.1 - 0.018 14.7 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KLO18951.1 - 0.019 15.1 0.0 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KLO18951.1 - 0.021 14.1 0.1 7.1 5.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.12 KLO18951.1 - 0.022 14.2 0.4 6.5 6.1 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein TIP49 PF06068.13 KLO18951.1 - 0.022 14.0 0.0 6.5 5.9 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain AAA PF00004.29 KLO18951.1 - 0.024 15.1 0.2 2.2 8.7 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KLO18951.1 - 0.032 14.2 0.3 1.8 8.4 0.0 3.3 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KLO18951.1 - 0.037 14.4 0.0 8.3 6.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 KLO18951.1 - 0.037 13.9 0.4 6.1 6.7 0.1 3.0 3 0 0 3 3 3 0 Adenylylsulphate kinase NB-ARC PF00931.22 KLO18951.1 - 0.039 13.2 0.1 2.7 7.1 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 KLO18951.1 - 0.042 13.9 0.9 12 5.8 0.0 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KLO18951.1 - 0.044 13.8 0.0 4.4 7.3 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 KLO18951.1 - 0.19 11.4 0.2 0.53 9.9 0.0 1.7 2 0 0 2 2 1 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 KLO18951.1 - 0.2 11.2 0.8 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KLO18951.1 - 0.25 11.7 0.9 10 6.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC_ATPase PF09818.9 KLO18951.1 - 0.51 9.1 3.0 0.8 8.4 0.1 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AIM5 PF17050.5 KLO18952.1 - 0.00053 20.7 0.1 0.00073 20.3 0.1 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Peptidase_S10 PF00450.22 KLO18953.1 - 1.1e-190 634.5 0.0 4.6e-99 332.7 0.0 3.0 3 0 0 3 3 3 3 Serine carboxypeptidase Dioxygenase_C PF00775.21 KLO18953.1 - 0.11 11.9 0.0 4.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Dioxygenase Pox_A9 PF04835.12 KLO18953.1 - 0.18 12.0 0.0 34 4.7 0.0 2.4 2 0 0 2 2 2 0 A9 protein conserved region YadA_head PF05658.14 KLO18953.1 - 0.7 10.4 3.3 32 5.0 0.2 2.8 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin BRO1 PF03097.18 KLO18954.1 - 1.1e-120 403.0 0.4 2.4e-120 401.9 0.3 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KLO18954.1 - 1e-55 189.1 6.4 1.6e-55 188.5 6.4 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV SRP68 PF16969.5 KLO18954.1 - 0.00081 18.5 0.1 0.0019 17.3 0.1 1.5 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Usp PF00582.26 KLO18955.1 - 2e-15 57.5 0.0 2.5e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Terminase_GpA PF05876.12 KLO18955.1 - 0.26 9.8 0.0 0.36 9.3 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) WW PF00397.26 KLO18956.1 - 5.9e-09 35.9 4.2 1.3e-08 34.8 4.2 1.6 1 0 0 1 1 1 1 WW domain CinA PF02464.17 KLO18957.1 - 5.9e-37 126.6 0.4 7.1e-37 126.4 0.4 1.0 1 0 0 1 1 1 1 Competence-damaged protein F-box-like PF12937.7 KLO18958.1 - 5.8e-10 38.9 2.8 7.2e-08 32.2 0.2 3.7 3 0 0 3 3 3 2 F-box-like F-box-like PF12937.7 KLO18959.1 - 1.4e-09 37.7 0.1 7.3e-08 32.2 0.1 2.9 2 0 0 2 2 2 1 F-box-like FHA PF00498.26 KLO18960.1 - 9.2e-05 22.7 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KLO18960.1 - 0.0069 16.7 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain ABC_tran PF00005.27 KLO18961.1 - 5.7e-44 149.9 0.1 6.4e-26 91.5 0.2 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KLO18961.1 - 3.5e-38 131.8 32.9 7.2e-20 71.8 1.6 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KLO18961.1 - 1.7e-11 44.0 8.9 0.008 15.6 0.0 4.3 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KLO18961.1 - 7.1e-07 29.3 5.1 0.014 15.2 0.0 4.4 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KLO18961.1 - 2.5e-06 28.0 0.3 0.12 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KLO18961.1 - 5.4e-06 27.0 6.2 0.00018 22.0 0.0 3.9 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.23 KLO18961.1 - 0.00023 21.2 0.2 0.089 12.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KLO18961.1 - 0.00034 20.3 0.5 0.15 11.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 KLO18961.1 - 0.00065 18.8 0.1 0.1 11.6 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein ResIII PF04851.15 KLO18961.1 - 0.0032 17.5 0.4 2 8.4 0.0 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KLO18961.1 - 0.0034 17.2 1.9 3.5 7.3 0.0 3.9 4 0 0 4 4 4 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KLO18961.1 - 0.0044 16.9 0.0 2.9 7.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 KLO18961.1 - 0.0061 16.1 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KLO18961.1 - 0.0068 16.9 0.0 5.9 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KLO18961.1 - 0.013 14.8 0.8 0.69 9.2 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_25 PF13481.6 KLO18961.1 - 0.015 14.9 0.1 7.8 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KLO18961.1 - 0.017 14.1 0.2 1.9 7.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 KLO18961.1 - 0.02 14.7 1.1 4.4 7.0 0.0 3.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase Dynamin_N PF00350.23 KLO18961.1 - 0.023 14.8 1.6 10 6.2 0.0 3.3 4 0 0 4 4 3 0 Dynamin family AAA_22 PF13401.6 KLO18961.1 - 0.024 14.9 0.8 6.7 7.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain Adeno_IVa2 PF02456.15 KLO18961.1 - 0.046 12.5 0.1 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein Zeta_toxin PF06414.12 KLO18961.1 - 0.071 12.4 0.0 8.8 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 KLO18961.1 - 0.087 12.9 4.8 1.4 9.0 0.5 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_15 PF13175.6 KLO18961.1 - 0.088 12.5 0.0 0.088 12.5 0.0 2.9 4 0 0 4 4 4 0 AAA ATPase domain AAA_5 PF07728.14 KLO18961.1 - 0.097 12.7 0.5 13 5.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_26 PF13500.6 KLO18961.1 - 0.12 12.2 0.2 9.6 6.0 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KLO18961.1 - 0.15 12.4 1.7 3.8 7.9 0.1 3.7 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KLO18961.1 - 0.39 10.4 7.9 1.5 8.5 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_11 PF13086.6 KLO18961.1 - 4.1 7.1 6.1 5.9 6.6 0.0 3.5 5 0 0 5 5 4 0 AAA domain Holin_9 PF16936.5 KLO18965.1 - 1.7 8.8 6.0 4.2 7.6 5.6 2.0 1 1 0 1 1 1 0 Putative holin DDE_1 PF03184.19 KLO18966.1 - 1.2e-07 31.6 0.1 5.1e-07 29.5 0.1 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Bestrophin PF01062.21 KLO18968.1 - 8.7e-36 123.8 0.0 2.9e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Phage_holin_3_1 PF05106.12 KLO18968.1 - 0.096 13.1 0.6 0.19 12.2 0.6 1.4 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) DUF952 PF06108.12 KLO18969.1 - 2.2e-21 75.7 0.0 3.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Pkinase_Tyr PF07714.17 KLO18970.1 - 1.8e-30 106.1 0.0 2e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO18970.1 - 1.9e-27 96.3 0.0 2.3e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO18970.1 - 0.0006 19.2 0.0 0.00089 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO18970.1 - 0.054 12.3 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RNA_POL_M_15KD PF02150.16 KLO18971.1 - 5.3e-12 45.4 1.4 5.3e-12 45.4 1.4 3.8 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 KLO18971.1 - 2.9e-11 43.0 0.8 2.9e-11 43.0 0.8 2.8 2 1 0 2 2 1 1 Transcription factor S-II (TFIIS) zf_UBZ PF18439.1 KLO18971.1 - 0.0012 18.4 3.9 4.4 7.0 0.1 3.5 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger RecR PF02132.15 KLO18971.1 - 0.007 15.9 6.9 0.023 14.2 0.5 3.1 3 0 0 3 3 3 1 RecR protein IBR PF01485.21 KLO18971.1 - 0.013 15.7 4.1 0.69 10.2 0.2 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain GFA PF04828.14 KLO18971.1 - 0.019 15.3 3.9 1.2 9.5 0.1 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.6 KLO18971.1 - 0.019 15.3 0.4 0.019 15.3 0.4 2.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar eIF-5_eIF-2B PF01873.17 KLO18971.1 - 0.061 13.2 4.9 0.47 10.3 0.3 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 C1_1 PF00130.22 KLO18971.1 - 0.093 12.6 0.5 0.093 12.6 0.5 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 KLO18971.1 - 0.098 12.7 8.7 2.2 8.4 1.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KLO18971.1 - 0.17 12.0 8.9 3.2 7.9 0.0 3.5 4 0 0 4 4 4 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KLO18971.1 - 0.29 11.1 6.6 1 9.4 1.0 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 KLO18971.1 - 0.32 10.5 9.6 0.2 11.2 2.5 3.3 3 1 0 3 3 3 0 TFIIB zinc-binding zf-RRN7 PF11781.8 KLO18971.1 - 0.34 10.6 0.1 0.34 10.6 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-ribbon_3 PF13248.6 KLO18971.1 - 0.79 9.2 11.9 1.2 8.6 0.9 3.8 4 0 0 4 4 4 0 zinc-ribbon domain DpnI PF06044.12 KLO18971.1 - 0.81 9.3 5.1 7.5 6.1 0.2 2.1 2 0 0 2 2 2 0 Dam-replacing family Elf1 PF05129.13 KLO18971.1 - 0.87 9.7 8.3 11 6.1 0.7 2.7 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Rpr2 PF04032.16 KLO18971.1 - 1 9.7 5.2 8.8 6.7 5.4 2.3 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2072 PF09845.9 KLO18971.1 - 1 9.6 3.8 22 5.3 0.0 2.9 3 0 0 3 3 3 0 Zn-ribbon containing protein DUF1610 PF07754.11 KLO18971.1 - 1.2 9.2 13.2 1.7 8.6 1.5 3.4 4 0 0 4 4 3 0 Domain of unknown function (DUF1610) zinc_ribbon_2 PF13240.6 KLO18971.1 - 1.6 8.5 9.5 4.3 7.2 0.5 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KLO18971.1 - 2 8.4 8.9 5.2 7.1 2.0 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 KLO18971.1 - 2.3 8.2 14.5 2.2 8.3 3.2 3.7 2 2 0 2 2 2 0 Nudix N-terminal zf-AN1 PF01428.16 KLO18971.1 - 3.1 8.1 10.3 7.7 6.8 0.3 3.6 3 1 0 3 3 3 0 AN1-like Zinc finger zinc_ribbon_9 PF14369.6 KLO18971.1 - 3.1 8.2 11.2 6.9 7.0 0.6 3.1 3 0 0 3 3 3 0 zinc-ribbon zf-ACC PF17848.1 KLO18971.1 - 3.9 7.6 11.7 21 5.3 0.2 3.9 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2_4 PF13894.6 KLO18971.1 - 5.3 8.1 11.2 10 7.3 0.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger G-alpha PF00503.20 KLO18972.1 - 3.7e-99 332.3 0.0 4.3e-99 332.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KLO18972.1 - 6.9e-15 54.9 0.3 6.9e-10 38.6 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KLO18972.1 - 0.0023 18.1 0.1 2.1 8.6 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KLO18972.1 - 0.013 14.8 0.2 0.88 8.9 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TniB PF05621.11 KLO18972.1 - 0.034 13.5 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 KLO18972.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family Glucan_synthase PF02364.15 KLO18974.1 - 0 1310.8 0.0 0 1310.4 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KLO18974.1 - 2.5e-40 137.8 1.3 6.9e-40 136.4 1.3 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 AA_permease_2 PF13520.6 KLO18976.1 - 9.2e-57 192.8 53.0 1.1e-56 192.5 53.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KLO18976.1 - 5.3e-21 74.8 48.0 7.3e-21 74.3 48.0 1.1 1 0 0 1 1 1 1 Amino acid permease Amidase PF01425.21 KLO18977.1 - 9.9e-80 268.7 0.0 9.4e-78 262.2 0.0 2.0 1 1 0 1 1 1 1 Amidase AAA PF00004.29 KLO18978.1 - 6.3e-12 46.1 0.0 7.5e-11 42.6 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KLO18978.1 - 0.045 13.8 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KLO18978.1 - 0.045 14.1 0.2 0.24 11.8 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KLO18978.1 - 0.1 12.9 1.6 1.6 9.0 0.0 3.0 2 1 1 3 3 3 0 AAA domain MeaB PF03308.16 KLO18978.1 - 0.16 10.9 0.1 0.28 10.1 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB F-box-like PF12937.7 KLO18979.1 - 6.8e-12 45.1 0.2 5.8e-11 42.1 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KLO18979.1 - 3 7.8 11.1 0.32 10.9 4.4 2.9 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KLO18980.1 - 2.7e-08 33.6 0.1 8.2e-08 32.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO18980.1 - 0.13 12.2 1.8 1.9 8.5 0.5 3.0 2 1 1 3 3 3 0 F-box domain Pro_isomerase PF00160.21 KLO18981.1 - 2.1e-46 158.1 0.0 3.1e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KLO18981.1 - 8.1e-06 25.6 0.7 0.039 14.1 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KLO18981.1 - 0.00056 19.6 0.2 0.11 12.4 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat HemY_N PF07219.13 KLO18981.1 - 0.63 10.3 2.2 3.4 7.9 0.9 2.1 1 1 1 2 2 2 0 HemY protein N-terminus TPR_6 PF13174.6 KLO18981.1 - 0.91 10.3 2.7 4 8.3 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF588 PF04535.12 KLO18982.1 - 0.0027 17.5 1.3 0.0027 17.5 1.3 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF588) DUF4064 PF13273.6 KLO18982.1 - 0.021 15.1 0.2 0.021 15.1 0.2 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF4064) HemY_N PF07219.13 KLO18982.1 - 0.074 13.2 0.1 26 5.1 0.1 3.1 3 0 0 3 3 3 0 HemY protein N-terminus DUF1516 PF07457.11 KLO18982.1 - 2.1 8.6 9.1 8.2 6.7 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1516) zf-NOSIP PF15906.5 KLO18983.1 - 3.8e-11 43.0 1.4 3.8e-11 43.0 1.4 1.8 2 0 0 2 2 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 KLO18983.1 - 1.5e-09 37.6 16.5 9.2e-06 25.4 7.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO18983.1 - 2.9e-07 30.3 19.5 5.7e-07 29.4 7.0 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KLO18983.1 - 4.8e-07 30.0 17.0 0.0002 21.6 8.0 2.4 2 0 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 KLO18983.1 - 9.1e-07 28.8 16.6 0.0006 19.8 1.6 2.4 2 0 0 2 2 2 2 RING-type zinc-finger Rtf2 PF04641.12 KLO18983.1 - 3.4e-06 26.6 12.9 6e-05 22.5 0.9 2.7 3 0 0 3 3 3 2 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 KLO18983.1 - 7.9e-06 25.6 19.9 0.0015 18.3 9.4 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO18983.1 - 1.9e-05 24.4 18.7 0.017 15.0 2.6 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO18983.1 - 0.00013 21.7 21.3 0.021 14.7 11.0 3.3 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 KLO18983.1 - 0.0054 16.6 6.2 0.0054 16.6 6.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KLO18983.1 - 0.11 12.4 9.5 1 9.3 0.3 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KLO18983.1 - 0.17 12.0 17.5 0.27 11.4 1.6 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KLO18983.1 - 0.41 11.0 10.3 0.14 12.4 3.4 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KLO18983.1 - 0.76 10.0 17.3 0.38 10.9 7.8 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 KLO18983.1 - 1.4 8.9 15.1 4.8 7.3 2.6 2.6 2 1 0 2 2 2 0 zinc-ribbons FYVE PF01363.21 KLO18983.1 - 3.6 7.8 13.6 1.5 9.0 3.8 2.9 2 1 0 2 2 2 0 FYVE zinc finger DZR PF12773.7 KLO18983.1 - 6.2 6.9 16.3 8.9 6.4 6.7 3.0 2 1 0 2 2 2 0 Double zinc ribbon F-box-like PF12937.7 KLO18984.1 - 1e-08 35.0 0.1 2.2e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO18985.1 - 3e-07 30.2 0.2 3e-07 30.2 0.2 2.8 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KLO18985.1 - 0.036 14.5 1.2 33 5.1 0.0 4.5 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) TB2_DP1_HVA22 PF03134.19 KLO18986.1 - 1.4e-26 92.2 2.6 2.4e-26 91.4 2.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TB2_DP1_HVA22 PF03134.19 KLO18987.1 - 9.9e-28 95.9 5.5 1.5e-27 95.3 5.5 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family BAH PF01426.18 KLO18988.1 - 3e-07 30.3 0.0 5.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KLO18988.1 - 0.0078 16.1 10.0 0.013 15.4 4.1 2.7 3 0 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.6 KLO18988.1 - 0.017 15.0 1.9 0.017 15.0 1.9 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KLO18988.1 - 0.13 12.6 6.4 2.2 8.7 3.0 2.6 2 0 0 2 2 2 0 Ring finger domain Zf_RING PF16744.5 KLO18988.1 - 0.18 11.9 3.7 0.098 12.8 0.7 2.1 3 0 0 3 3 3 0 KIAA1045 RING finger zinc_ribbon_9 PF14369.6 KLO18988.1 - 1.5 9.2 6.1 1.6 9.1 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon C1_1 PF00130.22 KLO18988.1 - 6.5 6.7 7.8 0.56 10.1 2.3 2.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MCM PF00493.23 KLO18989.1 - 3e-104 347.0 0.3 4.7e-104 346.4 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KLO18989.1 - 9.1e-38 128.9 0.1 1.8e-37 128.0 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KLO18989.1 - 6e-30 103.7 4.8 1.3e-29 102.5 4.8 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KLO18989.1 - 2.5e-24 85.5 3.0 5.1e-24 84.5 1.0 2.4 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KLO18989.1 - 7.2e-22 77.9 2.2 1.9e-21 76.6 2.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KLO18989.1 - 1.3e-07 31.2 0.0 1e-06 28.3 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KLO18989.1 - 0.00075 19.4 0.0 0.0033 17.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KLO18989.1 - 0.0027 17.4 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KLO18989.1 - 0.023 14.7 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) preATP-grasp_3 PF18301.1 KLO18990.1 - 0.088 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 pre ATP-grasp 3 domain DUF2397 PF09660.10 KLO18990.1 - 0.097 11.6 0.2 0.1 11.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) RelB_leu_zip PF16180.5 KLO18990.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 RelB leucine zipper Thaumatin PF00314.17 KLO18991.1 - 2.1e-72 243.2 7.9 2.4e-72 243.0 7.9 1.0 1 0 0 1 1 1 1 Thaumatin family ThiF PF00899.21 KLO18992.1 - 2.3e-42 145.1 0.0 3.4e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KLO18992.1 - 0.00012 22.4 0.4 0.0014 18.9 0.4 2.5 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KLO18992.1 - 0.0027 18.1 0.1 0.0078 16.6 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.24 KLO18992.1 - 0.013 15.1 0.9 0.034 13.7 0.7 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KLO18992.1 - 0.017 14.4 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KLO18992.1 - 0.017 14.3 0.1 0.028 13.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 KLO18992.1 - 0.033 13.8 0.1 0.073 12.6 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ELFV_dehydrog PF00208.21 KLO18992.1 - 0.048 13.4 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.18 KLO18992.1 - 0.096 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 KLO18993.1 - 1.4e-50 172.4 0.0 1.9e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Comm PF15957.5 KLO18993.1 - 0.16 12.3 1.0 17 5.8 0.3 2.4 2 0 0 2 2 2 0 Commissureless ABC_tran PF00005.27 KLO18997.1 - 3.5e-47 160.4 0.0 1.3e-28 100.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KLO18997.1 - 2.9e-43 148.5 25.2 4e-25 89.0 8.3 3.3 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KLO18997.1 - 2.7e-07 30.3 0.0 6.5e-05 22.5 0.0 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KLO18997.1 - 2.1e-05 23.7 0.1 0.23 10.5 0.1 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 KLO18997.1 - 3.2e-05 23.6 0.1 0.031 13.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KLO18997.1 - 0.00024 21.0 2.9 1.2 8.9 0.0 4.1 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KLO18997.1 - 0.00045 19.9 0.2 0.38 10.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KLO18997.1 - 0.0048 17.3 0.0 6.3 7.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KLO18997.1 - 0.011 16.3 1.8 2.5 8.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KLO18997.1 - 0.011 15.9 0.1 0.031 14.4 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain NACHT PF05729.12 KLO18997.1 - 0.022 14.7 1.5 5.3 6.9 0.0 3.4 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.6 KLO18997.1 - 0.056 13.7 0.2 41 4.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain AglB_L1 PF18079.1 KLO18997.1 - 0.097 13.0 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 Archaeal glycosylation protein B long peripheral domain AAA_7 PF12775.7 KLO18997.1 - 0.13 11.8 0.1 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KLO18997.1 - 0.14 12.0 0.1 17 5.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Pkinase PF00069.25 KLO18998.1 - 5.3e-49 167.0 0.0 1.8e-34 119.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO18998.1 - 3.1e-48 164.3 0.0 5.9e-38 130.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KLO18998.1 - 0.011 15.7 0.5 0.037 13.9 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO18998.1 - 0.014 14.7 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KLO18998.1 - 0.027 13.8 0.1 0.07 12.5 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 KLO18999.1 - 5.6e-54 178.9 23.0 8.8e-09 35.9 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO18999.1 - 8.7e-19 67.6 2.1 0.0018 18.5 0.1 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO18999.1 - 3.1e-10 40.3 0.3 0.00083 19.3 0.2 3.8 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KLO18999.1 - 2.1e-09 36.6 7.3 3.3e-05 22.8 0.3 4.2 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KLO18999.1 - 6.1e-06 25.4 7.1 0.073 12.0 0.0 4.7 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KLO18999.1 - 5.5e-05 21.9 0.1 0.00031 19.4 0.0 2.1 2 1 0 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.5 KLO18999.1 - 0.00011 21.6 2.0 0.014 14.8 0.2 3.0 3 1 0 3 3 3 1 WD40-like domain PALB2_WD40 PF16756.5 KLO18999.1 - 0.0017 17.4 2.8 2.8 6.8 0.1 3.8 1 1 3 4 4 4 2 Partner and localizer of BRCA2 WD40 domain CDtoxinA PF03498.14 KLO18999.1 - 0.0018 17.9 1.6 0.054 13.1 0.5 2.8 1 1 2 3 3 3 1 Cytolethal distending toxin A/C domain DUF1513 PF07433.11 KLO18999.1 - 0.0053 15.9 1.6 0.98 8.4 0.0 3.7 1 1 1 3 3 3 1 Protein of unknown function (DUF1513) Pectate_lyase22 PF14583.6 KLO18999.1 - 0.019 13.6 0.0 0.054 12.2 0.0 1.6 2 0 0 2 2 2 0 Oligogalacturonate lyase IKI3 PF04762.12 KLO18999.1 - 0.063 11.3 0.0 8 4.3 0.0 2.6 3 0 0 3 3 3 0 IKI3 family DUF5114 PF17141.4 KLO18999.1 - 2.2 8.9 4.2 55 4.4 0.0 3.3 2 1 1 3 3 2 0 Domain of unknown function (DUF5114) Pkinase_Tyr PF07714.17 KLO19000.1 - 3.1e-47 161.1 0.0 4.2e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO19000.1 - 9.3e-42 143.2 0.0 1.3e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO19000.1 - 1.5e-05 24.5 0.0 2.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO19000.1 - 0.0014 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase zf-C2H2_4 PF13894.6 KLO19000.1 - 0.0075 17.0 2.6 0.0075 17.0 2.6 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KLO19000.1 - 0.02 14.7 2.4 0.066 13.0 2.4 1.9 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-RING_7 PF02591.15 KLO19000.1 - 0.085 13.1 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 C4-type zinc ribbon domain DUF4379 PF14311.6 KLO19000.1 - 0.1 13.0 3.4 0.14 12.5 1.0 2.2 2 0 0 2 2 2 0 Probable Zinc-ribbon domain DUF411 PF04214.13 KLO19000.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF zf-C2HC_2 PF13913.6 KLO19000.1 - 1 9.3 11.1 0.15 12.0 1.5 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C4pol PF14260.6 KLO19000.1 - 2.1 8.9 5.6 20 5.8 0.0 2.8 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta zf-C2H2 PF00096.26 KLO19000.1 - 6.4 7.4 16.3 0.5 10.9 2.9 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Glyco_hydro_92 PF07971.12 KLO19001.1 - 3.2e-128 428.5 1.6 4e-128 428.2 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KLO19001.1 - 4.5e-52 177.3 4.7 6.6e-52 176.8 4.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Acetyltransf_1 PF00583.25 KLO19001.1 - 0.071 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Pkinase PF00069.25 KLO19003.1 - 7.2e-27 94.4 0.0 9e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19003.1 - 3.6e-23 82.2 0.0 4.5e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO19003.1 - 6.5e-06 25.2 0.0 8.3e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KLO19003.1 - 0.00026 20.6 0.0 0.00077 19.1 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KLO19003.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO19003.1 - 0.029 14.3 0.0 0.18 11.7 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO19003.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KLO19004.1 - 1.8e-62 211.4 0.2 2.6e-62 210.9 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO19004.1 - 0.03 13.7 0.2 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cullin_Nedd8 PF10557.9 KLO19004.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Cullin protein neddylation domain Thioredoxin_3 PF13192.6 KLO19004.1 - 0.17 12.0 0.1 0.41 10.7 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin domain Pkinase_fungal PF17667.1 KLO19005.1 - 1.6e-83 280.8 0.0 2.1e-83 280.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Merozoite_SPAM PF07133.11 KLO19005.1 - 0.00023 21.2 22.4 0.00044 20.3 22.4 1.4 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) Mpp10 PF04006.12 KLO19005.1 - 0.001 17.6 10.5 0.0018 16.8 10.5 1.4 1 0 0 1 1 1 1 Mpp10 protein Kdo PF06293.14 KLO19005.1 - 0.0024 17.2 0.6 1.3 8.3 0.1 3.0 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family SDA1 PF05285.12 KLO19005.1 - 0.012 15.1 14.2 0.024 14.1 14.2 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KLO19005.1 - 0.025 12.8 16.4 0.037 12.2 16.4 1.2 1 0 0 1 1 1 0 Nop14-like family Thioredoxin_3 PF13192.6 KLO19005.1 - 0.035 14.2 0.2 0.15 12.1 0.1 2.0 2 0 0 2 2 2 0 Thioredoxin domain Pkinase PF00069.25 KLO19005.1 - 0.037 13.4 0.1 0.096 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein kinase domain CDC45 PF02724.14 KLO19005.1 - 0.12 10.7 11.5 0.21 9.9 11.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 KLO19005.1 - 0.19 10.6 2.0 0.37 9.7 2.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) HEPN_AbiU2 PF18734.1 KLO19005.1 - 0.39 10.2 0.0 0.39 10.2 0.0 2.7 4 0 0 4 4 4 0 AbiU2 RR_TM4-6 PF06459.12 KLO19005.1 - 0.4 10.5 11.0 0.026 14.4 5.9 1.6 2 0 0 2 2 1 0 Ryanodine Receptor TM 4-6 Plasmodium_Vir PF05795.11 KLO19005.1 - 0.69 9.3 4.2 1.6 8.1 4.2 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4820 PF16091.5 KLO19005.1 - 1.4 8.2 3.9 2.7 7.3 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CobT PF06213.12 KLO19005.1 - 1.5 8.1 22.0 2.8 7.3 22.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CPSF100_C PF13299.6 KLO19005.1 - 2.8 8.1 9.6 0.31 11.2 4.7 1.8 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal Myc_N PF01056.18 KLO19005.1 - 3.8 7.3 8.9 7.5 6.3 8.9 1.5 1 0 0 1 1 1 0 Myc amino-terminal region SpoIIP PF07454.11 KLO19005.1 - 4 6.8 8.4 8.2 5.8 8.4 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIIF_alpha PF05793.12 KLO19005.1 - 6.8 5.2 21.5 10 4.6 21.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FGGY_N PF00370.21 KLO19006.1 - 3.1e-62 210.3 0.1 3.2e-60 203.8 0.1 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KLO19006.1 - 7.5e-62 208.6 0.9 1.1e-61 208.0 0.9 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF5444 PF17519.2 KLO19006.1 - 0.28 11.2 1.0 1.7 8.7 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5444) Glyco_hydro_47 PF01532.20 KLO19007.1 - 5.9e-133 444.1 0.0 6.9e-133 443.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2909 PF11137.8 KLO19007.1 - 0.14 12.1 0.5 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) zf-MYND PF01753.18 KLO19008.1 - 4.4e-08 33.1 9.3 4.4e-08 33.1 9.3 2.1 2 0 0 2 2 2 1 MYND finger UPF0242 PF06785.11 KLO19009.1 - 0.0078 16.3 0.4 0.012 15.8 0.4 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus FPP PF05911.11 KLO19009.1 - 0.011 13.9 9.1 0.015 13.5 9.1 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Laminin_II PF06009.12 KLO19009.1 - 0.019 15.0 6.0 0.025 14.6 5.0 1.7 1 1 0 1 1 1 0 Laminin Domain II EzrA PF06160.12 KLO19009.1 - 0.034 12.4 10.7 0.45 8.6 11.6 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF16 PF01519.16 KLO19009.1 - 0.036 14.6 2.6 0.073 13.6 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.9 KLO19009.1 - 0.067 13.2 18.0 0.2 11.7 7.1 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 KLO19009.1 - 0.088 13.0 13.2 0.13 12.4 13.2 1.2 1 0 0 1 1 1 0 Tropomyosin like HAUS-augmin3 PF14932.6 KLO19009.1 - 0.26 10.8 11.3 0.41 10.2 11.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 APG6_N PF17675.1 KLO19009.1 - 0.28 11.7 19.5 1.2 9.7 12.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 KLO19009.1 - 0.3 11.1 5.4 1.6 8.8 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ERM PF00769.19 KLO19009.1 - 0.32 10.8 13.0 0.5 10.2 13.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Spc7 PF08317.11 KLO19009.1 - 0.38 9.6 11.6 0.71 8.7 11.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 KLO19009.1 - 0.38 10.9 14.5 0.96 9.6 14.5 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) MPS2 PF17060.5 KLO19009.1 - 0.48 9.6 4.1 0.73 9.0 4.1 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF842 PF05811.13 KLO19009.1 - 0.56 9.9 4.4 1.9 8.2 0.4 2.2 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) PI3K_P85_iSH2 PF16454.5 KLO19009.1 - 0.61 9.7 10.8 2.4 7.7 10.8 1.8 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Exonuc_VII_L PF02601.15 KLO19009.1 - 0.76 9.3 6.5 1.1 8.7 6.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-H PF05837.12 KLO19009.1 - 1.2 9.6 15.5 4.5 7.7 2.6 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DMPK_coil PF08826.10 KLO19009.1 - 1.4 9.1 10.2 0.26 11.4 3.8 2.8 2 1 1 3 3 3 0 DMPK coiled coil domain like YabA PF06156.13 KLO19009.1 - 2.3 8.9 8.9 2.4 8.9 3.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Fez1 PF06818.15 KLO19009.1 - 2.4 8.6 9.3 3.7 8.0 9.3 1.2 1 0 0 1 1 1 0 Fez1 GAS PF13851.6 KLO19009.1 - 3.1 7.1 14.8 7.5 5.8 14.6 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 KLO19009.1 - 4 7.7 8.5 7 6.9 0.5 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 PRKG1_interact PF15898.5 KLO19009.1 - 6.9 7.6 11.5 1.3 9.9 5.1 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF2408 PF10303.9 KLO19010.1 - 1.1e-60 204.1 6.8 9.1e-43 146.1 0.1 4.5 4 2 0 4 4 4 4 Protein of unknown function (DUF2408) DUF5414 PF17435.2 KLO19010.1 - 0.2 11.3 1.3 0.44 10.2 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5414) DUF1664 PF07889.12 KLO19010.1 - 0.64 10.1 7.2 0.36 10.9 0.2 3.5 5 1 0 5 5 5 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 KLO19011.1 - 7.6e-45 152.6 27.2 9e-45 152.3 27.2 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KLO19011.1 - 1.7e-10 40.7 26.4 2.3e-06 27.2 14.6 2.6 1 1 1 2 2 2 2 Tropomyosin BRE1 PF08647.11 KLO19011.1 - 2.2e-05 24.4 22.9 0.00042 20.3 5.2 2.2 2 0 0 2 2 2 2 BRE1 E3 ubiquitin ligase GAS PF13851.6 KLO19011.1 - 0.00042 19.7 23.5 0.0046 16.3 9.3 2.3 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DHR10 PF18595.1 KLO19011.1 - 0.0015 18.6 26.9 0.12 12.5 11.8 2.3 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain HrpB7 PF09486.10 KLO19011.1 - 0.0015 18.9 15.4 0.01 16.2 3.8 2.5 1 1 1 2 2 2 2 Bacterial type III secretion protein (HrpB7) DUF3450 PF11932.8 KLO19011.1 - 0.0027 17.1 20.1 0.0059 15.9 8.3 2.0 1 1 0 2 2 2 2 Protein of unknown function (DUF3450) ERM PF00769.19 KLO19011.1 - 0.003 17.4 26.0 0.16 11.7 11.2 2.0 1 1 1 2 2 2 2 Ezrin/radixin/moesin family MscS_porin PF12795.7 KLO19011.1 - 0.0092 15.6 19.3 0.19 11.2 17.0 2.1 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain Alanine_zipper PF11839.8 KLO19011.1 - 0.012 15.9 9.5 1.1 9.6 0.7 3.4 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein Cep57_CLD_2 PF14197.6 KLO19011.1 - 0.013 15.6 25.7 0.44 10.7 5.8 3.2 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Fez1 PF06818.15 KLO19011.1 - 0.014 15.8 21.8 0.048 14.1 19.1 2.0 1 1 1 2 2 2 0 Fez1 WEMBL PF05701.11 KLO19011.1 - 0.015 14.0 22.5 0.016 13.9 22.5 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.9 KLO19011.1 - 0.015 15.3 4.9 0.015 15.3 4.9 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YscO PF07321.12 KLO19011.1 - 0.017 15.1 9.8 0.017 15.1 9.8 2.8 1 1 1 2 2 2 0 Type III secretion protein YscO ADIP PF11559.8 KLO19011.1 - 0.017 15.2 23.9 0.022 14.8 10.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 KLO19011.1 - 0.026 14.8 16.7 0.041 14.2 3.4 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Jnk-SapK_ap_N PF09744.9 KLO19011.1 - 0.027 14.7 25.6 0.024 14.9 13.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HMMR_N PF15905.5 KLO19011.1 - 0.03 13.8 22.2 0.039 13.4 22.2 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Tup_N PF08581.10 KLO19011.1 - 0.03 14.6 2.2 0.03 14.6 2.2 2.9 1 1 2 3 3 3 0 Tup N-terminal DUF1664 PF07889.12 KLO19011.1 - 0.041 13.9 11.2 0.14 12.2 3.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KLO19011.1 - 0.071 12.0 26.2 0.75 8.6 13.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Spectrin PF00435.21 KLO19011.1 - 0.083 13.4 18.5 0.51 10.8 8.0 2.8 1 1 1 2 2 2 0 Spectrin repeat TMF_TATA_bd PF12325.8 KLO19011.1 - 0.084 13.1 20.3 0.88 9.8 11.3 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 KLO19011.1 - 0.084 12.9 14.1 1.8 8.6 5.9 2.6 1 1 1 2 2 2 0 Laminin Domain II Med21 PF11221.8 KLO19011.1 - 0.1 12.9 16.7 5.3 7.3 16.7 2.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex OmpH PF03938.14 KLO19011.1 - 0.11 12.9 22.3 0.57 10.5 6.2 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) HIP1_clath_bdg PF16515.5 KLO19011.1 - 0.11 13.1 24.9 1.3 9.7 9.4 2.9 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 KLO19011.1 - 0.12 11.7 18.0 0.15 11.4 18.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 KLO19011.1 - 0.13 12.5 26.9 0.52 10.5 12.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Uso1_p115_C PF04871.13 KLO19011.1 - 0.13 12.6 28.8 0.088 13.2 12.6 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 KLO19011.1 - 0.17 12.0 29.0 0.9 9.6 6.8 3.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 KLO19011.1 - 0.18 12.2 13.3 6.4 7.3 0.9 4.7 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 KLO19011.1 - 0.19 11.6 25.0 0.091 12.6 10.6 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH T3SSipB PF16535.5 KLO19011.1 - 0.2 12.2 19.2 2.9 8.4 8.3 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB Sec34 PF04136.15 KLO19011.1 - 0.22 11.4 10.8 0.037 13.9 2.8 2.2 1 1 1 2 2 2 0 Sec34-like family She9_MDM33 PF05546.11 KLO19011.1 - 0.32 10.8 13.1 1.2 8.9 2.9 2.9 1 1 2 3 3 3 0 She9 / Mdm33 family DUF4200 PF13863.6 KLO19011.1 - 0.35 11.3 25.9 1.4 9.3 11.3 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.10 KLO19011.1 - 0.39 10.9 11.2 2.9 8.1 3.1 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Flagellin_C PF00700.21 KLO19011.1 - 0.41 11.1 3.4 7.7 7.0 0.1 3.0 1 1 1 3 3 3 0 Bacterial flagellin C-terminal helical region DUF919 PF06034.11 KLO19011.1 - 0.48 10.3 6.9 0.24 11.3 0.3 3.0 3 0 0 3 3 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) CLZ PF16526.5 KLO19011.1 - 0.5 10.8 19.8 3.8 7.9 7.7 3.6 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 KLO19011.1 - 0.58 10.8 13.5 0.42 11.3 1.7 3.3 1 1 2 3 3 3 0 SlyX KLRAQ PF10205.9 KLO19011.1 - 0.62 10.3 15.5 0.71 10.1 4.6 2.9 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DASH_Spc19 PF08287.11 KLO19011.1 - 0.62 9.9 20.4 0.26 11.2 15.4 2.2 1 1 1 2 2 2 0 Spc19 APG6_N PF17675.1 KLO19011.1 - 0.78 10.3 34.7 0.12 12.9 19.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region PspA_IM30 PF04012.12 KLO19011.1 - 0.9 9.1 24.1 10 5.6 23.9 2.2 1 1 0 1 1 1 0 PspA/IM30 family COG2 PF06148.11 KLO19011.1 - 1 9.4 11.5 1.4 9.0 1.3 2.6 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.15 KLO19011.1 - 1.1 8.7 13.9 1.7 8.2 13.9 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Csm1_N PF18504.1 KLO19011.1 - 1.2 9.6 18.1 1.7 9.0 4.9 3.8 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF3584 PF12128.8 KLO19011.1 - 1.2 6.6 23.8 6.2 4.2 23.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF745 PF05335.13 KLO19011.1 - 1.3 8.7 17.6 2.8 7.6 17.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Macoilin PF09726.9 KLO19011.1 - 1.4 7.4 19.2 2.2 6.7 7.3 2.0 1 1 1 2 2 2 0 Macoilin family DUF724 PF05266.14 KLO19011.1 - 1.5 8.6 20.9 2.4 8.0 6.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ApoO PF09769.9 KLO19011.1 - 1.7 8.6 5.1 32 4.5 0.8 3.0 1 1 2 3 3 3 0 Apolipoprotein O AAA_13 PF13166.6 KLO19011.1 - 1.8 7.1 20.2 5.1 5.6 20.2 1.7 1 1 0 1 1 1 0 AAA domain XhlA PF10779.9 KLO19011.1 - 2.6 8.3 22.7 1.1 9.5 2.6 4.0 1 1 3 4 4 4 0 Haemolysin XhlA UBA_e1_thiolCys PF10585.9 KLO19011.1 - 2.7 7.8 11.6 3.8 7.4 10.6 1.6 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site DUF16 PF01519.16 KLO19011.1 - 3 8.4 15.1 13 6.3 6.1 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 UPF0242 PF06785.11 KLO19011.1 - 3.1 7.9 24.6 1.5 8.9 12.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CCDC-167 PF15188.6 KLO19011.1 - 4.2 7.8 19.9 1 9.7 1.8 3.2 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 DUF812 PF05667.11 KLO19011.1 - 4.8 5.9 22.0 12 4.6 22.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TMPIT PF07851.13 KLO19011.1 - 5.5 6.1 15.7 5 6.3 7.4 2.0 1 1 1 2 2 2 0 TMPIT-like protein CREPT PF16566.5 KLO19011.1 - 6.2 7.0 14.8 2.3 8.4 5.0 2.5 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour KELK PF15796.5 KLO19011.1 - 8.2 7.0 23.6 1.3 9.5 1.3 3.7 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GvpK PF05121.12 KLO19011.1 - 8.4 6.5 11.5 0.31 11.1 1.6 2.9 2 1 0 2 2 2 0 Gas vesicle protein K Prefoldin_2 PF01920.20 KLO19011.1 - 8.9 6.3 23.7 5.3 7.1 5.1 3.8 1 1 0 2 2 2 0 Prefoldin subunit SelR PF01641.18 KLO19012.1 - 4.6e-49 165.5 0.1 5.3e-49 165.3 0.1 1.0 1 0 0 1 1 1 1 SelR domain ADD_ATRX PF17981.1 KLO19012.1 - 0.0024 17.7 0.1 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 Cysteine Rich ADD domain Tnp_zf-ribbon_2 PF13842.6 KLO19012.1 - 0.019 15.7 0.2 9.2 7.2 0.0 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon RIG-I_C-RD PF11648.8 KLO19012.1 - 0.14 12.4 0.0 1.4 9.2 0.0 2.0 2 0 0 2 2 2 0 C-terminal domain of RIG-I DZR PF12773.7 KLO19012.1 - 0.28 11.2 4.6 3.3 7.8 4.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon Tim44 PF04280.15 KLO19014.1 - 3e-35 121.5 0.5 6.3e-35 120.4 0.5 1.6 1 0 0 1 1 1 1 Tim44-like domain HTH_12 PF08461.10 KLO19014.1 - 0.08 12.9 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain CENP-O PF09496.10 KLO19014.1 - 0.31 11.0 3.9 0.21 11.5 1.7 1.8 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component DUF3813 PF12758.7 KLO19014.1 - 2.9 8.3 10.0 9.9 6.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) DUF2203 PF09969.9 KLO19014.1 - 9.4 7.0 7.2 2.7 8.7 2.4 2.3 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cyto_heme_lyase PF01265.17 KLO19015.1 - 2e-74 250.8 3.5 6.9e-73 245.8 3.5 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DNA_ligase_A_C PF04679.15 KLO19018.1 - 0.0079 16.8 0.1 0.032 14.8 0.1 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region CactinC_cactus PF09732.9 KLO19018.1 - 0.049 13.6 0.1 0.071 13.1 0.1 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein CPSase_L_D3 PF02787.19 KLO19018.1 - 0.1 13.0 0.1 0.68 10.3 0.0 2.0 1 1 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATG19_autophagy PF12744.7 KLO19022.1 - 0.03 13.5 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding DDE_3 PF13358.6 KLO19023.1 - 6.8e-08 32.4 0.0 7.2e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease AT_hook PF02178.19 KLO19024.1 - 0.067 13.1 3.4 0.39 10.8 3.4 2.5 1 0 0 1 1 1 0 AT hook motif IZUMO PF15005.6 KLO19025.1 - 0.039 14.5 0.4 0.082 13.4 0.4 1.5 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated UAA PF08449.11 KLO19029.1 - 2.2e-09 36.9 15.9 2.8e-09 36.6 15.9 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KLO19029.1 - 0.00062 19.9 7.7 0.00062 19.9 7.7 2.2 2 0 0 2 2 2 1 EamA-like transporter family CPSase_L_D2 PF02786.17 KLO19030.1 - 4.7e-80 268.1 0.1 1.7e-79 266.2 0.2 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KLO19030.1 - 1e-69 234.3 0.0 1.8e-69 233.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KLO19030.1 - 7.5e-41 139.1 0.1 1.6e-40 138.1 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KLO19030.1 - 4.8e-31 107.1 0.0 1.8e-30 105.2 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KLO19030.1 - 2.3e-29 102.8 0.0 5.5e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KLO19030.1 - 4.5e-17 61.7 5.1 4.5e-17 61.7 5.1 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KLO19030.1 - 4.8e-14 51.9 5.5 1.6e-07 31.1 0.4 2.9 2 0 0 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KLO19030.1 - 2.6e-10 40.2 0.0 5.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KLO19030.1 - 4e-07 29.8 0.2 1e-06 28.4 0.2 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KLO19030.1 - 1.4e-06 27.7 1.2 0.0014 17.9 0.2 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 KLO19030.1 - 3.3e-06 27.3 0.0 7.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KLO19030.1 - 5.7e-05 23.8 3.8 0.084 13.6 0.3 3.1 3 0 0 3 3 2 2 HlyD family secretion protein ATP-grasp_4 PF13535.6 KLO19030.1 - 0.00078 19.1 0.1 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain NQRA PF05896.11 KLO19030.1 - 0.0039 16.7 0.7 0.0093 15.4 0.7 1.6 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GARS_A PF01071.19 KLO19030.1 - 0.0093 15.7 0.5 0.02 14.6 0.0 1.8 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.9 KLO19030.1 - 0.014 15.4 3.0 1.2 9.1 2.9 3.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 KLO19030.1 - 0.015 15.3 3.4 0.045 13.7 2.3 2.4 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 KLO19030.1 - 0.08 12.7 2.0 0.74 9.6 0.6 3.0 2 1 1 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 KLO19030.1 - 0.088 13.0 2.0 0.22 11.8 0.4 2.6 2 0 0 2 2 1 0 Peptidase family M23 GCV_H PF01597.19 KLO19030.1 - 0.16 11.8 4.7 0.36 10.7 1.0 2.7 1 1 1 2 2 2 0 Glycine cleavage H-protein PNPase PF03726.14 KLO19030.1 - 0.21 12.1 0.8 0.62 10.6 0.2 2.2 2 0 0 2 2 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain YqfD PF06898.11 KLO19030.1 - 4.8 5.9 6.7 2 7.1 3.0 1.9 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD Biotin_lipoyl PF00364.22 KLO19031.1 - 4.5e-10 39.2 8.3 1.1e-09 37.9 8.3 1.6 1 1 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KLO19031.1 - 2e-06 27.5 10.7 0.00038 20.2 1.7 2.1 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 KLO19031.1 - 3.8e-06 27.5 5.3 0.0027 18.4 0.4 2.0 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 KLO19031.1 - 3.1e-05 23.3 3.0 0.0071 15.6 0.2 2.0 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 KLO19031.1 - 0.0036 17.2 8.6 0.052 13.5 8.6 2.0 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 KLO19031.1 - 0.024 14.1 3.9 0.039 13.4 0.8 1.9 1 1 1 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Peptidase_M23 PF01551.22 KLO19031.1 - 0.029 14.6 6.1 0.066 13.4 6.1 1.6 1 1 0 1 1 1 0 Peptidase family M23 ProQ_C PF17516.2 KLO19031.1 - 0.93 9.0 9.6 0.13 11.7 1.3 2.8 2 1 1 3 3 3 0 ProQ C-terminal domain Biotin_lipoyl PF00364.22 KLO19032.1 - 4.9e-06 26.3 4.1 0.0016 18.2 0.7 2.7 2 1 0 2 2 2 2 Biotin-requiring enzyme HlyD_D23 PF16576.5 KLO19032.1 - 0.00047 19.4 4.2 2.3 7.4 0.3 3.0 1 1 2 3 3 3 3 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 KLO19032.1 - 6.4 6.7 12.7 0.44 10.4 0.6 3.6 3 2 0 3 3 3 0 Biotin-lipoyl like NMO PF03060.15 KLO19033.1 - 3.4e-34 118.7 3.9 6.1e-29 101.5 0.7 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KLO19033.1 - 1.8e-08 33.8 0.1 0.0019 17.3 0.0 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KLO19033.1 - 6.7e-06 25.4 3.3 4e-05 22.8 0.8 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KLO19033.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KLO19033.1 - 0.05 13.1 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein LSM PF01423.22 KLO19034.1 - 1.1e-16 60.3 0.0 1.4e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain Enkurin PF13864.6 KLO19042.1 - 0.018 15.5 1.1 0.032 14.7 1.1 1.3 1 0 0 1 1 1 0 Calmodulin-binding zf-C4 PF00105.18 KLO19043.1 - 0.18 12.3 4.3 0.15 12.5 0.8 2.5 3 0 0 3 3 3 0 Zinc finger, C4 type (two domains) GlgS PF08971.11 KLO19045.1 - 0.056 13.5 1.6 0.13 12.3 0.3 2.2 2 0 0 2 2 2 0 Glycogen synthesis protein SET PF00856.28 KLO19047.1 - 0.31 11.4 1.2 0.97 9.8 0.6 2.3 2 1 0 2 2 2 0 SET domain SHR3_chaperone PF08229.11 KLO19048.1 - 2.1e-46 157.3 0.1 2.3e-46 157.2 0.1 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 F-box-like PF12937.7 KLO19049.1 - 0.032 14.1 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 F-box-like F-box_5 PF18511.1 KLO19049.1 - 0.23 11.1 0.8 1.1 8.8 0.2 2.4 2 0 0 2 2 2 0 F-box TPR_2 PF07719.17 KLO19051.1 - 1.2e-08 34.4 0.2 0.0014 18.6 0.0 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KLO19051.1 - 4.7e-08 32.5 0.6 0.0027 17.4 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KLO19051.1 - 7.8e-08 31.9 0.1 0.0033 17.1 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 KLO19051.1 - 1.8e-06 28.1 0.2 0.076 13.3 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KLO19051.1 - 3.3e-06 27.4 0.1 0.0027 18.4 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KLO19051.1 - 0.00022 21.6 0.2 0.023 15.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KLO19051.1 - 0.00023 21.1 1.7 0.49 10.8 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KLO19051.1 - 0.00099 19.7 0.1 0.047 14.3 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KLO19051.1 - 0.0015 18.4 0.1 0.51 10.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KLO19051.1 - 0.013 15.6 0.1 0.035 14.2 0.1 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KLO19051.1 - 0.03 15.0 0.2 13 6.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 KLO19051.1 - 0.071 13.2 0.1 3 7.9 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 KLO19051.1 - 0.093 12.6 1.8 5.6 7.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KLO19051.1 - 0.14 12.2 0.1 0.39 10.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KLO19051.1 - 0.18 11.9 0.2 0.58 10.3 0.0 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat NmrA PF05368.13 KLO19053.1 - 6.5e-27 94.6 0.0 8.7e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO19053.1 - 3.3e-09 36.9 0.0 5.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KLO19053.1 - 0.002 17.2 0.0 0.0029 16.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KLO19053.1 - 0.0043 17.1 0.0 0.0089 16.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 KLO19053.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KLO19053.1 - 0.2 10.9 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 KLO19054.1 - 1.5e-30 106.5 0.0 2e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO19054.1 - 3.7e-10 40.0 0.0 7.2e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KLO19054.1 - 1.6e-05 25.1 0.1 0.00022 21.5 0.1 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 KLO19054.1 - 0.0012 19.5 0.8 0.84 10.3 0.0 2.4 1 1 1 2 2 2 2 Homoserine dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KLO19054.1 - 0.0014 17.7 0.1 0.0021 17.1 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KLO19054.1 - 0.0021 18.1 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KLO19054.1 - 0.0037 17.5 0.1 0.0059 16.9 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KLO19054.1 - 0.005 17.4 0.6 0.019 15.6 0.4 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KLO19054.1 - 0.042 13.1 0.2 0.077 12.3 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 KLO19054.1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NmrA PF05368.13 KLO19055.1 - 3.3e-25 89.0 0.0 7.4e-25 87.9 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KLO19055.1 - 9.8e-10 38.6 0.0 1.7e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KLO19055.1 - 1.3e-05 25.5 0.0 0.0024 18.1 0.0 2.2 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 KLO19055.1 - 0.0039 16.7 0.1 0.0058 16.1 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 3Beta_HSD PF01073.19 KLO19055.1 - 0.0099 14.9 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family SBP_bac_8 PF13416.6 KLO19055.1 - 0.059 13.2 0.1 6.4 6.5 0.0 2.3 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein AlaDh_PNT_C PF01262.21 KLO19055.1 - 0.075 12.3 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RVT_1 PF00078.27 KLO19057.1 - 1.1e-08 34.9 0.0 3.7e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bromo_TP PF07524.13 KLO19057.1 - 0.31 11.1 1.2 2 8.5 0.0 2.7 3 0 0 3 3 3 0 Bromodomain associated DUF2183 PF09949.9 KLO19059.1 - 1.3e-26 92.8 0.0 4.4e-26 91.1 0.0 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KLO19059.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) SLC35F PF06027.12 KLO19060.1 - 1e-101 340.4 15.1 1.2e-101 340.2 15.1 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KLO19060.1 - 1.2e-08 34.3 0.7 1.9e-08 33.7 0.7 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KLO19060.1 - 0.013 15.7 2.3 0.013 15.7 2.3 3.1 2 1 1 3 3 3 0 EamA-like transporter family Deltameth_res PF16020.5 KLO19060.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.5 3 0 0 3 3 3 0 Deltamethrin resistance DUF543 PF04418.12 KLO19060.1 - 0.3 11.1 1.2 1.6 8.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Wzy_C PF04932.15 KLO19060.1 - 2.7 7.6 9.7 5.8e+02 0.0 9.7 3.0 1 1 0 1 1 1 0 O-Antigen ligase DUF5518 PF17647.1 KLO19060.1 - 6.4 7.0 16.6 0.031 14.4 5.6 2.7 3 1 0 3 3 3 0 Family of unknown function (DUF5518) DUF3487 PF11990.8 KLO19060.1 - 7.2 6.5 6.5 4.9 7.1 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3487) Ribosomal_S19 PF00203.21 KLO19061.1 - 3.5e-32 110.1 0.1 6.1e-32 109.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 KLO19062.1 - 1.7e-25 89.4 17.4 1.9e-25 89.2 17.4 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 KLO19062.1 - 0.068 11.6 2.7 0.08 11.4 2.7 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein EF-hand_14 PF17959.1 KLO19062.1 - 0.13 12.6 0.2 0.26 11.7 0.0 1.5 2 0 0 2 2 2 0 EF-hand domain ParA PF10609.9 KLO19064.1 - 1e-93 313.3 0.0 1.2e-93 313.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KLO19064.1 - 8.1e-08 32.4 0.0 2.6e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KLO19064.1 - 0.00031 20.7 0.1 0.0042 17.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KLO19064.1 - 0.00033 19.9 0.2 0.0023 17.2 0.1 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KLO19064.1 - 0.004 16.6 0.0 5.1 6.4 0.0 3.0 2 2 1 3 3 3 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 KLO19064.1 - 0.0082 16.0 0.0 0.032 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 KLO19064.1 - 0.013 15.0 0.0 0.078 12.5 0.0 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 KLO19064.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KLO19064.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 KLO19064.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RhoGAP PF00620.27 KLO19065.1 - 6.5e-38 129.9 0.1 1.6e-37 128.7 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KLO19065.1 - 8.5e-24 83.5 38.0 9.9e-11 41.7 8.6 4.7 5 0 0 5 5 5 4 LIM domain KAP PF05804.12 KLO19065.1 - 0.034 12.3 0.2 0.051 11.7 0.2 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Ribosomal_60s PF00428.19 KLO19066.1 - 4.4e-07 30.4 17.0 7.6e-05 23.2 17.0 2.9 1 1 0 1 1 1 1 60s Acidic ribosomal protein Fungal_trans PF04082.18 KLO19067.1 - 1.6e-12 47.1 0.1 3.7e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO19067.1 - 1.2e-09 38.1 9.4 2.1e-09 37.4 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Uds1 PF15456.6 KLO19067.1 - 0.26 11.4 2.2 0.36 11.0 0.2 2.1 3 0 0 3 3 3 0 Up-regulated During Septation Pkinase PF00069.25 KLO19068.1 - 5.9e-65 219.2 0.0 7.9e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19068.1 - 2.2e-33 115.6 0.0 3.1e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KLO19068.1 - 0.00095 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KLO19068.1 - 0.02 14.8 0.5 0.059 13.3 0.1 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KLO19068.1 - 0.058 12.7 0.1 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Symplekin_C PF12295.8 KLO19069.1 - 5e-64 215.8 0.8 1.7e-63 214.1 0.8 2.0 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 KLO19069.1 - 9.6e-54 182.4 0.0 2.3e-53 181.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HEAT PF02985.22 KLO19069.1 - 0.036 14.3 0.0 0.67 10.4 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 KLO19069.1 - 0.62 10.6 2.3 20 5.8 0.1 4.3 5 0 0 5 5 5 0 HEAT-like repeat V-ATPase_G PF03179.15 KLO19070.1 - 2.9e-32 111.3 16.1 3.5e-32 111.1 16.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit RdRP_3 PF00998.23 KLO19070.1 - 0.048 12.4 4.2 0.057 12.1 4.2 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase ATP-synt_B PF00430.18 KLO19070.1 - 0.26 11.4 14.4 0.086 12.9 11.1 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Phasin PF05597.11 KLO19070.1 - 0.48 10.4 11.3 1.8 8.6 2.0 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) V-ATPase_G_2 PF16999.5 KLO19070.1 - 0.89 10.0 12.6 9.5 6.7 1.0 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF4407 PF14362.6 KLO19070.1 - 2.7 7.3 9.0 3 7.1 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Voltage_CLC PF00654.20 KLO19071.1 - 9.8e-85 284.9 24.4 9.8e-85 284.9 24.4 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KLO19071.1 - 1.9e-09 37.8 0.5 0.00029 21.2 0.0 3.1 3 0 0 3 3 3 2 CBS domain MMS19_C PF12460.8 KLO19073.1 - 1.5e-94 317.5 7.1 1.2e-92 311.2 0.5 3.6 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KLO19073.1 - 1.5e-88 296.8 0.1 9.5e-87 290.9 0.0 3.1 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 KLO19073.1 - 6.4e-06 26.6 2.5 0.048 14.2 0.1 5.3 6 0 0 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 KLO19073.1 - 0.0026 18.1 3.9 5.9 7.4 0.1 5.0 4 0 0 4 4 4 1 HEAT repeats Acyl-CoA_dh_C PF12806.7 KLO19073.1 - 0.016 15.3 0.2 0.27 11.4 0.1 2.6 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Methyltransf_28 PF02636.17 KLO19074.1 - 1.4e-37 129.7 0.0 2.1e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 KLO19074.1 - 5e-05 22.5 0.0 7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 KLO19074.1 - 0.0055 17.4 0.0 0.016 16.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO19074.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KLO19074.1 - 0.023 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain NepR PF18557.1 KLO19074.1 - 0.34 10.6 2.0 4.7 6.9 0.2 3.0 3 0 0 3 3 3 0 Anti-sigma factor NepR Kei1 PF08552.11 KLO19075.1 - 7e-50 169.6 4.8 1.3e-49 168.7 4.8 1.4 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 p450 PF00067.22 KLO19076.1 - 1.2e-61 208.9 0.0 1.4e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3083 PF11281.8 KLO19076.1 - 0.12 11.7 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) DUF2920 PF11144.8 KLO19076.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Methyltransf_2 PF00891.18 KLO19077.1 - 3.6e-22 78.7 0.0 8.2e-21 74.3 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KLO19077.1 - 0.00032 20.7 0.0 0.00079 19.4 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.12 KLO19077.1 - 0.00042 21.0 0.0 0.00082 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO19077.1 - 0.011 16.4 0.0 0.027 15.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KLO19077.1 - 0.027 14.0 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KLO19077.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 KLO19078.1 - 1.9e-53 181.4 0.4 2.2e-53 181.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO19078.1 - 1.4e-51 174.7 1.7 1.7e-51 174.4 1.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO19078.1 - 5.7e-09 36.1 0.6 1.1e-08 35.2 0.6 1.5 1 1 0 1 1 1 1 KR domain Glyco_hydro_99 PF16317.5 KLO19079.1 - 0.01 15.0 0.2 0.015 14.4 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 99 NmrA PF05368.13 KLO19080.1 - 5.5e-31 107.9 0.0 7.4e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO19080.1 - 1.2e-15 57.8 0.0 2.4e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KLO19080.1 - 3.8e-06 26.1 0.0 5.3e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KLO19080.1 - 0.00012 22.3 0.0 0.00088 19.5 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 KLO19080.1 - 0.00043 20.9 0.2 0.28 11.8 0.1 2.3 1 1 0 2 2 2 2 Homoserine dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KLO19080.1 - 0.00082 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KLO19080.1 - 0.0015 18.1 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KLO19080.1 - 0.002 18.4 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Glu_dehyd_C PF16912.5 KLO19080.1 - 0.0027 17.2 0.1 0.0041 16.6 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KLO19080.1 - 0.0028 17.0 0.1 0.005 16.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 KLO19080.1 - 0.0041 17.9 0.0 0.0068 17.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF2095 PF09868.9 KLO19080.1 - 0.043 13.8 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) Ldh_1_N PF00056.23 KLO19080.1 - 0.11 12.6 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_99 PF16317.5 KLO19082.1 - 0.0018 17.5 0.1 0.0024 17.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 FMO-like PF00743.19 KLO19083.1 - 2.2e-21 75.9 0.0 1.8e-19 69.6 0.0 2.8 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KLO19083.1 - 1.3e-19 70.6 0.0 4.2e-15 55.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KLO19083.1 - 5.5e-13 48.8 0.3 1.2e-11 44.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KLO19083.1 - 2.1e-10 40.8 0.0 0.018 15.0 0.1 3.3 3 0 0 3 3 3 3 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KLO19083.1 - 5.4e-09 35.7 0.0 7.8e-06 25.3 0.2 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO19083.1 - 3.6e-08 33.4 0.5 0.057 13.0 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO19083.1 - 2.1e-07 31.1 0.1 3.2e-06 27.3 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KLO19083.1 - 1.5e-06 27.2 0.7 0.0076 15.0 0.4 3.0 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.27 KLO19083.1 - 8.8e-05 23.0 0.5 0.2 12.2 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KLO19083.1 - 0.00014 21.1 0.4 0.03 13.4 0.6 2.3 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KLO19083.1 - 0.00044 19.6 0.0 0.06 12.6 0.1 2.7 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KLO19083.1 - 0.00066 19.0 0.3 0.0012 18.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Mqo PF06039.15 KLO19083.1 - 0.00086 18.0 0.0 0.0014 17.3 0.0 1.3 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 KLO19083.1 - 0.0017 17.7 0.3 0.0046 16.2 0.1 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 KLO19083.1 - 0.0029 18.0 0.0 3.4 8.2 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding Shikimate_DH PF01488.20 KLO19083.1 - 0.016 15.3 0.4 0.59 10.2 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KLO19083.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KLO19083.1 - 0.041 13.2 0.0 0.7 9.2 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KLO19083.1 - 0.15 11.1 4.1 4 6.4 0.6 2.9 4 0 0 4 4 4 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KLO19083.1 - 0.17 11.1 1.6 2.2 7.5 0.3 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KLO19083.1 - 0.2 10.6 0.1 1.7 7.6 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 KLO19083.1 - 0.4 10.3 1.9 0.34 10.6 0.4 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KLO19083.1 - 0.7 9.7 2.6 1 9.2 0.3 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KLO19083.1 - 0.89 10.2 2.8 5.4 7.7 0.3 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PQ-loop PF04193.14 KLO19084.1 - 4.6e-30 103.2 7.8 7.4e-18 64.1 0.2 2.8 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KLO19084.1 - 0.0037 18.1 1.9 1.5 9.6 0.1 2.7 2 1 0 2 2 2 2 ER lumen protein retaining receptor MtN3_slv PF03083.16 KLO19084.1 - 0.066 13.3 0.7 0.066 13.3 0.7 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange BatA PF07584.11 KLO19084.1 - 0.21 12.0 2.7 25 5.3 0.0 3.1 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal CcmD PF04995.14 KLO19084.1 - 9.1 6.5 7.7 0.43 10.7 1.0 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) TPT PF03151.16 KLO19085.1 - 4.9e-55 186.9 19.7 5.7e-55 186.7 19.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KLO19085.1 - 3.8e-12 46.5 26.6 4e-07 30.3 8.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KLO19085.1 - 1.4e-10 40.9 18.4 1.6e-10 40.7 18.4 1.1 1 0 0 1 1 1 1 UAA transporter family Rsm1 PF08600.10 KLO19085.1 - 0.03 14.5 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 Rsm1-like ABC_tran PF00005.27 KLO19086.1 - 4.3e-21 75.9 0.0 8.8e-21 74.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KLO19086.1 - 4e-06 26.4 2.2 0.016 14.6 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KLO19086.1 - 0.00023 21.0 0.1 0.00038 20.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KLO19086.1 - 0.00046 20.1 0.2 0.0086 15.9 0.1 2.4 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KLO19086.1 - 0.0018 18.0 0.1 0.0035 17.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KLO19086.1 - 0.0023 18.4 0.2 0.0065 17.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KLO19086.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 KLO19086.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KLO19086.1 - 0.028 14.7 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KLO19086.1 - 0.074 13.4 0.1 0.18 12.2 0.1 1.9 1 1 1 2 2 2 0 AAA ATPase domain KH_2 PF07650.17 KLO19086.1 - 0.075 12.9 0.1 0.47 10.3 0.0 2.3 3 0 0 3 3 3 0 KH domain Zeta_toxin PF06414.12 KLO19086.1 - 0.091 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KLO19086.1 - 0.12 11.7 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KLO19087.1 - 1.6e-20 74.0 0.0 3e-20 73.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KLO19087.1 - 1.2e-06 28.2 0.2 0.0042 16.5 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KLO19087.1 - 0.00066 19.6 0.0 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KLO19087.1 - 0.0008 19.2 0.0 0.0014 18.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KLO19087.1 - 0.0041 16.8 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KLO19087.1 - 0.013 15.2 0.0 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KLO19087.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KLO19087.1 - 0.055 13.7 0.1 0.29 11.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KLO19087.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KLO19087.1 - 0.12 12.9 0.1 0.29 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KLO19087.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain SCA7 PF08313.12 KLO19088.1 - 1.6e-27 95.2 0.1 1.6e-27 95.2 0.1 2.2 2 0 0 2 2 2 1 SCA7, zinc-binding domain IF4E PF01652.18 KLO19089.1 - 9.8e-53 178.2 0.1 1.2e-52 177.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1917 PF08939.10 KLO19089.1 - 0.09 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) Erv26 PF04148.13 KLO19089.1 - 0.18 11.6 0.2 0.29 10.9 0.2 1.2 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 Tmemb_14 PF03647.13 KLO19090.1 - 5e-20 72.0 7.4 5.8e-20 71.8 7.4 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF3188 PF11384.8 KLO19090.1 - 4.2 7.2 6.7 3.4 7.4 1.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3188) SIR2 PF02146.17 KLO19092.1 - 2.2e-60 203.6 0.0 3.3e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KLO19092.1 - 6e-07 29.4 1.2 6.4e-05 22.8 0.5 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KLO19092.1 - 0.018 14.7 0.1 0.64 9.7 0.1 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Acetyltransf_10 PF13673.7 KLO19093.1 - 4.4e-07 29.9 0.0 6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO19093.1 - 1.1e-06 28.9 0.0 1.5e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KLO19093.1 - 8e-05 23.0 0.0 0.00013 22.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO19093.1 - 0.0055 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein RVT_1 PF00078.27 KLO19096.1 - 4.5e-06 26.3 0.0 8.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TP_methylase PF00590.20 KLO19097.1 - 1.3e-41 142.9 1.6 2.2e-41 142.1 1.6 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KLO19097.1 - 5.2e-13 49.3 0.1 1.7e-12 47.6 0.1 2.0 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KLO19097.1 - 2.3e-09 36.8 0.1 2.7e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KLO19097.1 - 3.7e-09 35.9 0.0 7.6e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Hydrolase_4 PF12146.8 KLO19099.1 - 1.9e-10 40.4 0.0 2.5e-09 36.8 0.0 2.3 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KLO19099.1 - 3.4e-08 33.4 0.9 2.2e-07 30.8 0.1 2.7 2 2 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO19099.1 - 1.1e-05 26.2 0.2 3.2e-05 24.7 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KLO19099.1 - 0.0035 17.3 0.0 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal ABC_tran PF00005.27 KLO19100.1 - 6.5e-22 78.5 0.0 1.1e-21 77.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KLO19100.1 - 2.9e-06 27.3 0.4 0.0034 17.3 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KLO19100.1 - 2.9e-05 23.6 0.2 0.15 11.4 0.8 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KLO19100.1 - 0.00014 21.8 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO19100.1 - 0.031 14.6 0.0 0.099 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KLO19100.1 - 0.033 14.7 0.1 0.1 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KLO19100.1 - 0.037 13.8 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KLO19100.1 - 0.056 13.8 0.1 0.2 12.0 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KLO19100.1 - 0.07 12.9 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KLO19100.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase EspB_PE PF18625.1 KLO19100.1 - 0.15 12.6 0.1 4.1 7.9 0.0 2.4 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain ABC_tran PF00005.27 KLO19102.1 - 2.4e-21 76.7 0.0 4.8e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KLO19102.1 - 7.9e-07 29.2 0.3 0.0029 17.5 0.0 3.2 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KLO19102.1 - 9.7e-05 21.9 0.1 0.15 11.5 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KLO19102.1 - 0.00056 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO19102.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KLO19102.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KLO19102.1 - 0.096 13.2 0.1 0.26 11.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KLO19102.1 - 0.1 13.0 0.0 0.3 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain DUF4350 PF14258.6 KLO19102.1 - 0.14 12.6 0.0 0.86 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) RsgA_GTPase PF03193.16 KLO19102.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 KLO19102.1 - 0.16 11.7 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ribosomal_L5_C PF00673.21 KLO19103.1 - 1e-21 76.9 0.0 1.6e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KLO19103.1 - 5.1e-20 71.6 0.6 1.3e-19 70.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 KLO19103.1 - 0.027 14.2 0.5 0.053 13.2 0.5 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain DAGAT PF03982.13 KLO19104.1 - 1.7e-97 325.9 0.0 1.9e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF2121 PF09894.9 KLO19105.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) Rxt3 PF08642.10 KLO19106.1 - 0.0013 19.5 0.8 0.22 12.3 0.0 3.6 3 0 0 3 3 3 2 Histone deacetylation protein Rxt3 DUF1640 PF07798.11 KLO19107.1 - 7.2e-60 202.0 12.3 8.6e-60 201.8 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Rep_2 PF01719.17 KLO19107.1 - 0.04 13.7 0.1 0.07 12.9 0.1 1.5 1 0 0 1 1 1 0 Plasmid replication protein Docking PF08990.11 KLO19107.1 - 0.044 13.4 0.7 0.17 11.5 0.7 2.1 1 0 0 1 1 1 0 Erythronolide synthase docking DDE_Tnp_IS1 PF03400.13 KLO19107.1 - 0.66 10.3 3.2 6.2 7.2 0.1 2.8 1 1 3 4 4 4 0 IS1 transposase CCDC23 PF15674.5 KLO19107.1 - 0.94 9.5 5.1 0.36 10.9 0.2 2.5 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 23 Fib_alpha PF08702.10 KLO19107.1 - 6 7.0 10.7 0.5 10.5 2.4 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ran_BP1 PF00638.18 KLO19108.1 - 1.6e-16 60.7 0.0 2.9e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain ESCRT-II PF05871.12 KLO19109.1 - 4.4e-33 114.5 0.0 5.2e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit ABC_tran PF00005.27 KLO19110.1 - 6.8e-23 81.7 0.0 1.1e-22 81.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KLO19110.1 - 3.2e-07 30.5 1.1 0.0036 17.2 0.2 2.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KLO19110.1 - 2.6e-06 27.0 0.3 0.068 12.6 0.6 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KLO19110.1 - 0.0016 18.2 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KLO19110.1 - 0.011 16.0 0.0 0.042 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KLO19110.1 - 0.014 15.1 0.1 0.03 14.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KLO19110.1 - 0.016 15.7 0.1 0.032 14.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KLO19110.1 - 0.029 14.8 0.0 0.097 13.1 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 KLO19110.1 - 0.061 12.5 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.6 KLO19110.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KLO19110.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 KLO19110.1 - 0.19 11.0 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin F-box-like PF12937.7 KLO19111.1 - 5.4e-07 29.4 1.1 3.7e-06 26.7 1.1 2.4 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO19112.1 - 6.2e-07 29.2 1.9 6.2e-07 29.2 1.9 2.5 2 1 0 2 2 2 1 F-box-like DWNN PF08783.11 KLO19113.1 - 2.2e-29 101.5 0.5 4.4e-29 100.6 0.5 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KLO19113.1 - 1.7e-10 40.5 6.5 1.7e-10 40.5 6.5 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 KLO19113.1 - 4.2e-06 26.6 1.7 1.2e-05 25.2 1.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KLO19113.1 - 0.00027 20.8 0.4 0.00068 19.5 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KLO19113.1 - 0.0027 17.4 0.7 0.0027 17.4 0.7 2.0 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-C3HC4_2 PF13923.6 KLO19113.1 - 0.0034 17.2 8.3 0.0034 17.2 8.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO19113.1 - 0.032 14.3 6.3 0.068 13.2 6.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Fib_alpha PF08702.10 KLO19113.1 - 0.09 13.0 3.3 0.2 11.8 3.3 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family zf-C3HC4_4 PF15227.6 KLO19113.1 - 0.17 12.1 8.8 0.4 10.9 8.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KLO19113.1 - 0.21 11.4 4.8 0.43 10.4 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain BLOC1S3 PF15753.5 KLO19113.1 - 0.22 11.7 5.3 0.52 10.4 5.3 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Ku_C PF03730.14 KLO19113.1 - 0.28 11.9 9.3 3.4 8.4 0.2 3.4 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm zf-C3HC4_3 PF13920.6 KLO19113.1 - 0.39 10.6 11.6 0.027 14.3 5.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4428 PF14471.6 KLO19113.1 - 0.49 10.4 4.9 0.5 10.3 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C3HC4 PF00097.25 KLO19113.1 - 0.75 9.7 9.0 1.6 8.7 9.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO19113.1 - 1.6 9.1 13.1 0.037 14.4 6.6 1.7 2 0 0 2 2 1 0 Ring finger domain BST2 PF16716.5 KLO19113.1 - 2.1 9.0 11.0 0.38 11.4 6.8 1.9 2 0 0 2 2 1 0 Bone marrow stromal antigen 2 zf_UBZ PF18439.1 KLO19113.1 - 4.1 7.1 9.1 0.99 9.1 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf_C2H2_10 PF18414.1 KLO19113.1 - 6.6 6.4 6.6 0.4 10.3 0.9 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger HATPase_c PF02518.26 KLO19114.1 - 2.9e-22 79.3 0.0 2e-21 76.6 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KLO19114.1 - 1.5e-17 63.8 0.1 2.1e-09 37.5 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 KLO19114.1 - 4e-07 30.0 0.2 1.2e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KLO19114.1 - 0.015 15.1 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ISN1 PF06437.11 KLO19114.1 - 0.09 11.7 0.1 0.14 11.0 0.1 1.1 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase DUF3810 PF12725.7 KLO19114.1 - 0.33 10.3 3.7 0.5 9.7 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Ribosomal_L28e PF01778.17 KLO19115.1 - 1.6e-38 131.9 2.0 1.6e-38 131.9 2.0 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KLO19115.1 - 3.4e-28 98.2 12.3 3.4e-28 98.2 12.3 2.9 1 1 2 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.10 KLO19115.1 - 0.0014 18.1 16.1 0.0017 17.8 16.1 1.1 1 0 0 1 1 1 1 BUD22 F-box-like PF12937.7 KLO19117.1 - 4.3e-08 32.9 0.4 4.3e-08 32.9 0.4 2.4 2 1 0 2 2 2 1 F-box-like Ribosomal_L28 PF00830.19 KLO19117.1 - 0.067 13.4 0.0 4.8 7.5 0.0 2.6 2 0 0 2 2 2 0 Ribosomal L28 family ArgJ PF01960.18 KLO19118.1 - 1.5e-137 458.3 0.9 1.8e-137 458.1 0.9 1.0 1 0 0 1 1 1 1 ArgJ family MetallophosN PF16371.5 KLO19118.1 - 0.075 13.3 0.5 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase PNK3P PF08645.11 KLO19121.1 - 7.4e-44 149.3 0.1 1.1e-43 148.7 0.1 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KLO19121.1 - 3.3e-10 40.3 0.0 1.4e-07 31.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain LNS2 PF08235.13 KLO19121.1 - 0.00023 20.7 0.0 0.00037 20.1 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) SRPRB PF09439.10 KLO19121.1 - 0.087 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit E1-E2_ATPase PF00122.20 KLO19122.1 - 2.1 7.8 4.3 0.98 8.9 0.9 2.2 2 0 0 2 2 2 0 E1-E2 ATPase Ribosomal_L35Ae PF01247.18 KLO19123.1 - 1.2e-44 150.4 0.3 1.3e-44 150.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KLO19123.1 - 0.0005 20.2 0.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Abhydrolase_3 PF07859.13 KLO19124.1 - 3.9e-16 59.6 0.0 7.9e-16 58.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KLO19124.1 - 0.00012 21.7 0.0 0.13 11.7 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KLO19124.1 - 0.00058 18.9 0.0 0.0009 18.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KLO19124.1 - 0.00079 18.8 0.0 0.0028 17.0 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 zf-RING_2 PF13639.6 KLO19125.1 - 1.4e-09 38.1 3.7 1.3e-08 35.0 0.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KLO19125.1 - 1.3e-08 34.9 2.6 1.4e-08 34.9 0.4 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KLO19125.1 - 4.4e-07 29.6 5.7 1e-06 28.4 1.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KLO19125.1 - 3.2e-06 26.8 1.4 0.0056 16.4 0.1 2.4 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 KLO19125.1 - 5e-05 23.1 3.9 6.7e-05 22.7 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO19125.1 - 8.6e-05 22.4 0.4 0.00022 21.1 0.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KLO19125.1 - 0.00019 21.2 0.8 0.00019 21.2 0.8 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KLO19125.1 - 0.00021 21.1 2.7 0.00024 20.9 0.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KLO19125.1 - 0.0025 17.8 0.2 0.0063 16.5 0.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KLO19125.1 - 0.0026 17.3 0.6 0.0055 16.3 0.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KLO19125.1 - 0.012 15.6 0.8 0.012 15.6 0.8 2.4 2 0 0 2 2 2 0 RING-type zinc-finger PQ-loop PF04193.14 KLO19125.1 - 0.016 14.9 0.8 0.046 13.5 0.8 1.7 1 0 0 1 1 1 0 PQ loop repeat zf-RING_4 PF14570.6 KLO19125.1 - 0.14 12.0 1.0 0.32 10.8 1.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KLO19125.1 - 1.2 9.4 4.0 1.7 8.9 1.9 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 KLO19125.1 - 9.1 6.5 8.3 0.35 11.0 2.3 1.7 2 0 0 2 2 1 0 RING-variant domain Nnf1 PF03980.14 KLO19126.1 - 3.5e-13 49.9 0.7 7.2e-13 48.9 0.7 1.5 1 0 0 1 1 1 1 Nnf1 APG6_N PF17675.1 KLO19126.1 - 0.00043 20.8 3.5 0.00067 20.2 3.5 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region CASP_C PF08172.12 KLO19126.1 - 0.00063 19.2 0.9 0.00091 18.6 0.9 1.3 1 0 0 1 1 1 1 CASP C terminal ATG16 PF08614.11 KLO19126.1 - 0.0024 18.2 3.6 0.0036 17.5 3.6 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc24 PF08286.11 KLO19126.1 - 0.0072 16.5 0.6 0.011 15.9 0.6 1.3 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 Jnk-SapK_ap_N PF09744.9 KLO19126.1 - 0.0093 16.2 1.8 0.0093 16.2 1.8 1.7 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 Herpes_BLRF2 PF05812.12 KLO19126.1 - 0.035 14.2 4.9 0.044 13.9 4.1 1.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein UPF0242 PF06785.11 KLO19126.1 - 0.047 13.8 1.6 0.059 13.5 1.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KLO19126.1 - 0.063 12.6 0.9 0.074 12.4 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KLO19126.1 - 0.22 10.6 3.7 0.26 10.3 3.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 KLO19126.1 - 0.23 11.9 9.5 0.67 10.4 8.9 2.0 1 1 1 2 2 2 0 Cell division protein ZapB IL32 PF15225.6 KLO19126.1 - 1.3 9.4 4.4 5.1 7.5 4.4 2.0 1 1 0 1 1 1 0 Interleukin 32 DivIC PF04977.15 KLO19126.1 - 9.7 6.0 9.0 1.4 8.7 4.4 1.9 2 0 0 2 2 2 0 Septum formation initiator zf-C2H2_jaz PF12171.8 KLO19127.1 - 1.4e-10 41.2 1.6 2.1e-10 40.6 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KLO19127.1 - 0.00013 22.2 1.0 0.00027 21.2 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KLO19127.1 - 0.021 15.2 0.2 0.021 15.2 0.2 1.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) IQ PF00612.27 KLO19127.1 - 0.14 12.1 0.6 0.14 12.1 0.6 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif zf-C2H2_4 PF13894.6 KLO19127.1 - 0.21 12.5 0.3 0.21 12.5 0.3 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Pirin PF02678.16 KLO19128.1 - 2.7e-27 94.9 1.7 4.3e-27 94.2 1.7 1.2 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KLO19128.1 - 9.8e-06 25.2 1.0 0.00095 18.8 0.9 2.3 2 0 0 2 2 2 2 Cupin domain Pirin_C_2 PF17954.1 KLO19128.1 - 0.0024 18.0 0.1 0.053 13.7 0.0 3.1 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain UQ_con PF00179.26 KLO19129.1 - 1.1e-17 64.0 0.0 1.3e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KLO19129.1 - 0.036 14.3 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain VHS PF00790.19 KLO19130.1 - 1.9e-26 92.6 1.3 3.1e-26 91.9 1.3 1.3 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KLO19130.1 - 6.7e-17 60.8 0.1 1.2e-16 60.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KLO19130.1 - 7.1e-15 54.6 0.1 1.4e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KLO19130.1 - 3.2e-13 49.1 0.1 6.7e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KLO19130.1 - 1.6e-11 44.4 2.1 1.3e-10 41.4 0.7 2.6 2 0 0 2 2 2 1 GAT domain Anoctamin PF04547.12 KLO19131.1 - 1.1e-103 347.5 2.0 1.4e-103 347.1 2.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel WD40 PF00400.32 KLO19136.1 - 3.3e-60 198.6 30.8 1.3e-09 38.5 0.1 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19136.1 - 3.8e-21 75.2 1.5 0.0039 17.4 0.0 6.1 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KLO19136.1 - 1.8e-09 38.0 0.1 4e-09 36.9 0.1 1.6 1 1 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KLO19136.1 - 2.7e-08 32.9 2.1 0.00038 19.2 0.0 3.7 3 1 2 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KLO19136.1 - 1.5e-05 24.1 0.1 0.75 8.7 0.0 4.1 5 0 0 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KLO19136.1 - 0.0012 17.7 0.0 2.1 7.0 0.0 3.3 4 0 0 4 4 4 2 Nup133 N terminal like GspH PF12019.8 KLO19136.1 - 0.021 15.3 2.0 0.031 14.7 0.5 2.1 2 0 0 2 2 2 0 Type II transport protein GspH IKI3 PF04762.12 KLO19136.1 - 0.047 11.7 0.1 0.072 11.1 0.1 1.2 1 0 0 1 1 1 0 IKI3 family RAB3GAP2_N PF14655.6 KLO19136.1 - 0.2 10.9 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Frtz PF11768.8 KLO19136.1 - 0.25 9.6 0.0 3.5 5.8 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz HOIP-UBA PF16678.5 KLO19138.1 - 0.023 14.7 0.1 0.031 14.3 0.1 1.3 1 1 0 1 1 1 0 HOIP UBA domain pair Mit_ribos_Mrp51 PF11709.8 KLO19139.1 - 1.8e-08 34.4 2.8 8.4e-07 28.9 2.8 2.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ferritin PF00210.24 KLO19139.1 - 0.039 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain Nuc_sug_transp PF04142.15 KLO19140.1 - 1.4e-93 313.5 9.9 4.4e-93 311.9 9.9 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KLO19140.1 - 0.0008 19.6 5.0 0.0008 19.6 5.0 3.3 3 1 0 3 3 3 1 EamA-like transporter family UAA PF08449.11 KLO19140.1 - 0.0019 17.5 12.7 0.011 15.0 12.7 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 KLO19140.1 - 0.021 14.2 0.9 0.021 14.2 0.9 2.8 3 1 0 3 3 3 0 Triose-phosphate Transporter family FAM53 PF15242.6 KLO19140.1 - 0.23 11.2 9.3 0.5 10.1 9.3 1.4 1 0 0 1 1 1 0 Family of FAM53 DUF4231 PF14015.6 KLO19140.1 - 8.1 7.0 8.3 0.67 10.4 1.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) MMM1 PF10296.9 KLO19141.1 - 1.4e-12 47.3 0.0 1.1e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Radical_SAM_C PF16199.5 KLO19142.1 - 1e-29 102.3 0.0 2e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KLO19142.1 - 2.2e-17 64.0 0.1 7.5e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KLO19142.1 - 1.4e-09 38.2 0.2 3e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KLO19142.1 - 6.1e-06 26.2 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KLO19142.1 - 0.0066 16.9 0.1 0.019 15.4 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF515 PF04415.12 KLO19143.1 - 0.058 11.8 9.0 0.12 10.7 9.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Rep_fac-A_C PF08646.10 KLO19144.1 - 4.6e-51 172.4 3.5 3.5e-49 166.3 3.2 2.7 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KLO19144.1 - 1.3e-34 118.0 0.0 2.5e-33 113.9 0.0 2.6 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 KLO19144.1 - 1.7e-22 79.3 0.6 4.1e-22 78.1 0.6 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KLO19144.1 - 1.5e-13 50.5 0.0 1.9e-11 43.8 0.0 2.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KLO19144.1 - 1.9e-06 27.8 2.5 0.71 9.5 0.1 3.4 3 1 0 3 3 3 3 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 KLO19144.1 - 1.2e-05 25.5 0.1 0.00038 20.7 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF223 DUF4539 PF15072.6 KLO19144.1 - 0.0005 20.1 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) DUF5521 PF17659.1 KLO19144.1 - 0.0083 14.0 0.1 0.75 7.6 0.0 2.8 2 1 0 2 2 2 1 Family of unknown function (DUF5521) PLATZ PF04640.14 KLO19144.1 - 0.092 13.4 1.0 0.24 12.1 0.3 2.1 2 0 0 2 2 2 0 PLATZ transcription factor Peptidase_M16_M PF16187.5 KLO19145.1 - 1.2e-85 287.2 0.1 8.9e-85 284.4 0.0 2.1 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KLO19145.1 - 1.6e-37 128.8 0.2 6.1e-36 123.6 0.2 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KLO19145.1 - 3.1e-26 92.5 0.0 4.5e-12 46.3 0.0 3.2 4 0 0 4 4 4 2 Peptidase M16 inactive domain Spectrin_like PF18373.1 KLO19145.1 - 0.14 12.3 0.5 5.8 7.1 0.1 2.7 2 0 0 2 2 2 0 Spectrin like domain NIF PF03031.18 KLO19146.1 - 7.7e-21 74.5 0.0 1.4e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 KLO19146.1 - 5.2e-08 32.5 0.0 9.5e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF1681 PF07933.14 KLO19147.1 - 2.6e-54 182.9 0.0 3.1e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Rab_eff_C PF04698.12 KLO19147.1 - 0.066 11.5 0.0 0.071 11.4 0.0 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus DUF4628 PF15429.6 KLO19147.1 - 0.3 10.7 2.8 0.5 10.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) Glyco_hydro_6 PF01341.17 KLO19148.1 - 2.2e-105 352.8 1.6 2.9e-105 352.4 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KLO19148.1 - 2.2e-14 53.1 8.3 2.2e-14 53.1 8.3 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Aminotran_5 PF00266.19 KLO19149.1 - 1.3e-92 310.6 0.0 1.6e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KLO19149.1 - 1.4e-07 31.1 0.0 1.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KLO19149.1 - 1.1e-05 25.0 0.1 7.7e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KLO19149.1 - 0.0029 16.4 0.0 0.0045 15.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 KLO19149.1 - 0.0087 14.6 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.19 KLO19149.1 - 0.099 12.7 0.0 5.8 7.0 0.0 2.5 2 0 0 2 2 2 0 B12 binding domain Fungal_trans PF04082.18 KLO19150.1 - 1.4e-07 30.9 0.0 2.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO19150.1 - 4.8e-06 26.6 13.6 1.6e-05 24.9 13.6 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Matrilin_ccoil PF10393.9 KLO19150.1 - 0.02 14.8 0.1 0.049 13.5 0.1 1.7 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin RRM_1 PF00076.22 KLO19151.1 - 1.8e-28 98.2 0.1 8.8e-18 63.9 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KLO19151.1 - 5.1e-05 23.3 0.1 0.47 10.6 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 RRM_5 PF13893.6 KLO19151.1 - 0.0015 18.1 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KLO19151.1 - 0.055 13.5 0.0 4.6 7.4 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 KLO19151.1 - 0.087 12.8 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 KLO19151.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated CAP_GLY PF01302.25 KLO19152.1 - 7.7e-19 67.5 0.2 1.4e-18 66.7 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KLO19152.1 - 2.7e-13 49.9 7.0 0.00082 19.7 0.2 5.6 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KLO19152.1 - 1e-08 34.9 0.2 1.5e-06 27.8 0.0 2.5 1 1 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 KLO19152.1 - 6.8e-08 32.2 7.6 0.0065 16.2 0.3 5.3 2 1 4 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 KLO19152.1 - 0.0022 18.3 6.9 12 6.9 0.1 6.2 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 KLO19152.1 - 0.004 17.1 1.5 41 4.6 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich repeat AP_endonuc_2_N PF07582.12 KLO19152.1 - 0.11 12.2 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 AP endonuclease family 2 C terminus ECH_2 PF16113.5 KLO19153.1 - 9.2e-112 373.8 0.0 1.4e-111 373.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KLO19153.1 - 1.3e-25 90.1 0.0 1.1e-24 87.1 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase FliG_N PF14842.6 KLO19153.1 - 0.012 16.1 0.1 0.22 12.1 0.0 2.2 2 0 0 2 2 2 0 FliG N-terminal domain DUF2497 PF10691.9 KLO19153.1 - 0.23 11.9 1.8 0.98 9.9 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2497) IDO PF01231.18 KLO19154.1 - 7.7e-125 417.1 0.0 9e-125 416.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CKS PF01111.19 KLO19155.1 - 2.1e-35 120.8 0.2 2.9e-35 120.3 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Pkinase PF00069.25 KLO19156.1 - 4.4e-45 154.1 0.0 5.5e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19156.1 - 7.9e-27 94.2 0.0 1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO19156.1 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO19156.1 - 0.018 15.0 0.4 0.056 13.3 0.4 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KLO19156.1 - 0.14 11.8 0.1 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 RIO1 family NUDIX PF00293.28 KLO19157.1 - 1.1e-11 44.9 0.0 1.4e-10 41.4 0.0 2.2 1 1 0 1 1 1 1 NUDIX domain eIF-3c_N PF05470.12 KLO19158.1 - 1.2e-167 558.8 29.5 8.8e-167 556.0 29.5 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KLO19158.1 - 1.9e-13 50.8 0.0 2.6e-12 47.1 0.0 2.9 3 0 0 3 3 3 1 PCI domain CENP-B_dimeris PF09026.10 KLO19158.1 - 0.058 13.8 8.3 0.19 12.1 8.3 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ABC_membrane PF00664.23 KLO19159.1 - 2.3e-76 257.1 32.3 3.3e-40 138.5 8.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KLO19159.1 - 4.6e-64 215.0 0.0 4.5e-32 111.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KLO19159.1 - 2.5e-17 63.1 0.1 8.2e-07 28.7 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KLO19159.1 - 6.9e-13 49.1 0.1 0.0025 17.7 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KLO19159.1 - 7.3e-09 36.2 0.4 0.00046 20.6 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KLO19159.1 - 1.1e-08 35.0 0.1 1.2 8.8 0.1 4.4 4 0 0 4 4 4 3 IstB-like ATP binding protein ABC_ATPase PF09818.9 KLO19159.1 - 1.6e-08 33.8 0.1 0.0047 15.8 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 KLO19159.1 - 5.3e-08 33.2 0.1 0.031 14.6 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KLO19159.1 - 8.3e-08 31.9 0.1 0.014 15.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KLO19159.1 - 7.8e-06 25.9 0.0 0.014 15.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KLO19159.1 - 1.1e-05 25.3 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KLO19159.1 - 1.5e-05 25.2 0.3 0.23 11.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KLO19159.1 - 4.1e-05 23.4 3.1 0.17 11.6 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KLO19159.1 - 5.1e-05 23.8 0.0 0.33 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KLO19159.1 - 8.4e-05 21.9 0.0 0.42 9.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.14 KLO19159.1 - 9.4e-05 22.4 0.2 0.55 10.2 0.0 3.4 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KLO19159.1 - 0.00028 20.9 0.0 1.3 9.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 KLO19159.1 - 0.0006 20.4 0.0 0.085 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KLO19159.1 - 0.00066 19.3 0.7 1.8 8.1 0.0 3.9 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.15 KLO19159.1 - 0.00091 19.2 0.0 0.67 9.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain DUF87 PF01935.17 KLO19159.1 - 0.0011 19.1 0.4 0.38 10.8 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 KLO19159.1 - 0.0014 19.0 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase G-alpha PF00503.20 KLO19159.1 - 0.0014 17.8 0.0 0.33 10.1 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit PRK PF00485.18 KLO19159.1 - 0.0016 18.3 0.0 0.4 10.4 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 KLO19159.1 - 0.0024 18.1 3.7 0.65 10.2 0.2 3.1 2 2 1 3 3 2 1 AAA domain AAA_19 PF13245.6 KLO19159.1 - 0.0032 17.8 0.1 4.7 7.5 0.1 3.0 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 KLO19159.1 - 0.0064 16.1 0.1 1.7 8.2 0.0 2.9 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA PF00004.29 KLO19159.1 - 0.011 16.1 0.0 15 6.0 0.0 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 KLO19159.1 - 0.021 15.0 0.0 5.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain CoaE PF01121.20 KLO19159.1 - 0.023 14.4 0.4 3.7 7.2 0.0 2.9 3 0 0 3 3 3 0 Dephospho-CoA kinase DUF2075 PF09848.9 KLO19159.1 - 0.024 13.9 0.2 9.3 5.4 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KLO19159.1 - 0.024 14.2 0.1 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 KLO19159.1 - 0.026 14.4 0.2 8.3 6.3 0.1 2.7 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 KLO19159.1 - 0.039 13.1 0.0 1.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TniB PF05621.11 KLO19159.1 - 0.041 13.3 0.1 8 5.8 0.0 3.7 4 0 0 4 4 4 0 Bacterial TniB protein APS_kinase PF01583.20 KLO19159.1 - 0.044 13.7 1.0 3 7.7 0.0 3.2 4 0 0 4 4 3 0 Adenylylsulphate kinase Mg_chelatase PF01078.21 KLO19159.1 - 0.044 13.2 0.0 12 5.3 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 KLO19159.1 - 0.051 13.8 4.4 13 6.1 0.3 4.2 4 2 0 4 4 2 0 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.6 KLO19159.1 - 0.052 12.6 0.1 4.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_17 PF13207.6 KLO19159.1 - 0.06 13.8 1.1 7.2 7.0 0.2 2.8 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KLO19159.1 - 0.061 13.2 0.1 21 5.0 0.0 2.9 2 1 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 KLO19159.1 - 0.071 12.8 0.0 12 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KLO19159.1 - 0.077 12.8 0.2 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.18 KLO19159.1 - 0.083 12.6 0.0 7.8 6.2 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KLO19159.1 - 0.084 12.0 0.0 15 4.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 KLO19159.1 - 0.09 12.1 0.1 16 4.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase PF06745.13 KLO19159.1 - 0.1 11.9 0.9 3.1 7.1 0.1 2.9 3 0 0 3 3 3 0 KaiC CbiA PF01656.23 KLO19159.1 - 0.11 12.6 0.1 3.6 7.6 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KLO19159.1 - 0.17 12.0 0.1 5.7 7.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dyp_perox PF04261.12 KLO19160.1 - 4.7e-08 32.4 0.0 1.4e-06 27.5 0.0 2.6 2 1 0 2 2 2 2 Dyp-type peroxidase family COesterase PF00135.28 KLO19162.1 - 6.6e-64 216.6 0.0 9.1e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KLO19162.1 - 9.8e-10 38.6 0.0 2.4e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Epimerase PF01370.21 KLO19163.1 - 7.4e-22 78.0 0.6 1.5e-20 73.7 0.6 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO19163.1 - 7.5e-13 48.1 0.0 1.3e-11 44.1 0.0 2.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KLO19163.1 - 4.3e-12 46.3 2.6 4.4e-12 46.3 1.6 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KLO19163.1 - 1.1e-10 41.2 0.0 8.1e-06 25.2 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 KLO19163.1 - 1.2e-08 34.8 0.8 2.8e-07 30.3 0.9 2.1 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KLO19163.1 - 3.3e-06 26.4 0.2 8e-06 25.2 0.2 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KLO19163.1 - 9.6e-06 25.2 0.3 3.4e-05 23.4 0.3 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KLO19163.1 - 0.006 16.1 0.1 0.041 13.3 0.3 2.2 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KLO19163.1 - 0.052 12.6 0.5 0.29 10.2 0.0 2.3 3 1 0 3 3 3 0 RmlD substrate binding domain Epimerase PF01370.21 KLO19164.1 - 3.1e-23 82.5 0.4 7.3e-23 81.3 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KLO19164.1 - 1e-12 48.3 2.3 1.1e-12 48.2 0.8 1.8 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KLO19164.1 - 1.3e-12 47.3 0.3 2e-11 43.5 0.1 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KLO19164.1 - 1.7e-10 40.5 0.1 3.2e-07 29.8 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 KLO19164.1 - 1.9e-08 34.2 0.6 3.2e-08 33.4 0.6 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KLO19164.1 - 8.8e-08 31.6 0.1 1.9e-06 27.2 0.2 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KLO19164.1 - 1e-06 28.4 0.3 1.2e-05 24.9 0.3 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KLO19164.1 - 0.0015 17.7 1.2 0.006 15.7 1.2 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KLO19164.1 - 0.0072 15.8 1.0 0.052 13.0 0.6 2.5 3 1 0 3 3 3 1 short chain dehydrogenase SRP40_C PF05022.12 KLO19165.1 - 4.3e-28 98.0 2.3 4.3e-28 98.0 2.3 2.8 3 0 0 3 3 3 1 SRP40, C-terminal domain DMRL_synthase PF00885.19 KLO19166.1 - 4.2e-57 191.9 0.1 5.2e-57 191.6 0.1 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF2108 PF09881.9 KLO19166.1 - 0.13 12.3 0.2 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2108) DUF1349 PF07081.11 KLO19166.1 - 0.17 11.6 0.0 18 5.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1349) Ank_4 PF13637.6 KLO19167.1 - 7.9e-11 42.3 1.0 2e-05 25.1 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KLO19167.1 - 1e-09 38.4 0.4 8.2e-09 35.6 0.2 2.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KLO19167.1 - 1.1e-09 38.8 0.0 1.5e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KLO19167.1 - 3.4e-08 33.1 0.0 0.00011 22.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KLO19167.1 - 1e-07 32.1 0.2 0.00025 21.4 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat ATP_bind_3 PF01171.20 KLO19168.1 - 3.9e-45 153.8 0.0 5.6e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 PP-loop family FAD_binding_3 PF01494.19 KLO19170.1 - 2.2e-19 69.9 0.1 5.6e-19 68.6 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KLO19170.1 - 0.0012 19.0 0.1 0.0037 17.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KLO19170.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KLO19170.1 - 0.14 11.4 0.0 0.37 10.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KLO19171.1 - 2.8e-46 158.3 0.0 9e-46 156.6 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO19171.1 - 6.6e-29 101.3 0.0 1.1e-28 100.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KLO19171.1 - 0.047 13.9 0.0 0.68 10.2 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GATA PF00320.27 KLO19172.1 - 5.8 6.6 7.7 0.46 10.1 2.3 2.2 2 1 0 2 2 2 0 GATA zinc finger BTB PF00651.31 KLO19173.1 - 0.019 15.2 0.0 0.21 11.8 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain SDA1 PF05285.12 KLO19173.1 - 1.2 8.5 11.0 1.4 8.2 11.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KLO19173.1 - 7.4 4.6 11.1 9.2 4.3 11.1 1.0 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.32 KLO19174.1 - 1.5e-57 190.2 13.0 6.1e-09 36.4 0.0 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19174.1 - 1.2e-16 60.7 1.2 1.9e-06 28.0 0.1 5.2 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KLO19174.1 - 1.2e-05 24.2 10.1 0.6 8.7 0.2 6.1 5 2 2 7 7 7 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KLO19174.1 - 0.15 11.0 0.7 4.7 6.1 0.0 3.2 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein YTH PF04146.15 KLO19175.1 - 2.5e-39 134.9 1.1 8.5e-39 133.2 0.1 2.3 2 0 0 2 2 2 1 YT521-B-like domain MFS_1 PF07690.16 KLO19176.1 - 3e-20 72.5 31.3 4e-20 72.1 31.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KLO19177.1 - 1.5e-22 80.1 35.8 1.9e-22 79.7 35.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ilm1 PF10311.9 KLO19179.1 - 0.0056 16.3 0.5 0.0091 15.7 0.5 1.4 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 MFS_1 PF07690.16 KLO19180.1 - 2e-54 184.9 41.2 3.4e-54 184.1 41.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KLO19180.1 - 1.6e-16 59.8 16.1 2.2e-16 59.4 16.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KLO19180.1 - 1.1e-14 54.1 12.5 1.1e-14 54.1 12.5 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 KLO19180.1 - 4.2e-08 32.2 19.6 5.1e-07 28.6 3.4 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein B12D PF06522.11 KLO19180.1 - 0.19 11.6 0.2 0.75 9.6 0.2 2.1 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit OATP PF03137.20 KLO19180.1 - 7.5 4.7 10.4 1.7 6.9 1.1 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1948 PF09185.10 KLO19181.1 - 0.15 11.9 0.1 0.24 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) GMC_oxred_N PF00732.19 KLO19184.1 - 1e-67 228.6 0.0 1.3e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO19184.1 - 3.1e-33 115.3 0.0 5.2e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KLO19184.1 - 0.00041 19.7 0.2 0.0037 16.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO19184.1 - 0.00044 19.6 0.0 0.06 12.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO19184.1 - 0.0011 19.1 0.1 0.0025 18.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KLO19184.1 - 0.0018 17.6 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KLO19184.1 - 0.0047 16.0 0.1 0.0095 15.0 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KLO19184.1 - 0.0058 16.2 0.2 0.035 13.7 0.4 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KLO19184.1 - 0.015 15.8 0.3 0.71 10.5 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HHH PF00633.23 KLO19184.1 - 0.068 13.1 1.0 3.1 7.9 0.0 3.3 3 0 0 3 3 3 0 Helix-hairpin-helix motif TrkA_N PF02254.18 KLO19184.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.24 KLO19184.1 - 0.23 10.5 0.1 0.37 9.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain GMC_oxred_N PF00732.19 KLO19185.1 - 7.4e-65 219.2 0.0 9.5e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO19185.1 - 5.3e-34 117.8 0.0 8.3e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KLO19185.1 - 4.9e-05 22.6 1.6 0.1 11.7 0.6 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KLO19185.1 - 0.00017 21.7 0.9 0.0013 18.9 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KLO19185.1 - 0.0013 17.8 0.1 0.002 17.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KLO19185.1 - 0.0027 17.0 0.2 0.0043 16.3 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KLO19185.1 - 0.013 14.8 0.1 0.041 13.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO19185.1 - 0.046 13.3 0.1 0.15 11.6 0.0 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KLO19185.1 - 0.053 12.2 0.3 0.15 10.7 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 KLO19185.1 - 0.068 12.4 0.1 0.8 8.9 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3029 PF11230.8 KLO19186.1 - 0.1 10.9 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) DASH_Dad3 PF08656.10 KLO19188.1 - 2.7e-22 78.6 0.0 3.3e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 K-box PF01486.17 KLO19188.1 - 0.039 14.1 0.1 0.05 13.8 0.1 1.1 1 0 0 1 1 1 0 K-box region GMC_oxred_N PF00732.19 KLO19189.1 - 2.1e-66 224.3 0.0 2.7e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO19189.1 - 4.3e-33 114.8 0.0 7.1e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KLO19189.1 - 0.00011 21.4 0.5 0.055 12.5 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KLO19189.1 - 0.0004 20.5 0.2 0.0013 18.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KLO19189.1 - 0.0006 19.0 0.1 0.00093 18.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KLO19189.1 - 0.00062 19.1 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KLO19189.1 - 0.0019 17.9 0.7 0.012 15.2 0.4 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO19189.1 - 0.0021 17.4 0.4 0.058 12.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO19189.1 - 0.0025 17.1 0.3 0.2 10.9 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO19189.1 - 0.19 10.4 0.4 0.72 8.5 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein GMC_oxred_N PF00732.19 KLO19190.1 - 2.8e-62 210.8 0.0 4.9e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO19190.1 - 6.9e-34 117.4 0.0 1.3e-33 116.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KLO19190.1 - 2.2e-05 24.6 0.2 4.9e-05 23.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KLO19190.1 - 6.1e-05 22.2 0.1 0.00011 21.4 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KLO19190.1 - 0.00026 20.3 0.2 0.00055 19.2 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KLO19190.1 - 0.00074 18.7 0.6 0.0032 16.6 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KLO19190.1 - 0.0021 17.4 0.7 0.11 11.7 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO19190.1 - 0.0035 16.6 0.1 0.0062 15.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KLO19190.1 - 0.0043 16.7 0.9 0.0043 16.7 0.9 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KLO19190.1 - 0.011 14.5 0.1 0.019 13.7 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KLO19190.1 - 0.034 13.2 0.4 6.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 KLO19190.1 - 0.11 12.7 0.1 0.28 11.4 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 KLO19190.1 - 0.16 11.2 0.5 0.83 8.8 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KLO19190.1 - 0.31 9.9 1.5 0.5 9.2 0.2 2.0 3 0 0 3 3 3 0 Tryptophan halogenase MFS_1 PF07690.16 KLO19191.1 - 2.2e-22 79.5 33.2 3.5e-22 78.8 33.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PHO4 PF01384.20 KLO19192.1 - 0.039 13.0 4.2 0.1 11.7 4.2 1.6 1 1 0 1 1 1 0 Phosphate transporter family NAD_binding_4 PF07993.12 KLO19193.1 - 1.8e-30 106.0 0.0 4.2e-30 104.8 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 KLO19193.1 - 1.2e-28 99.9 0.0 9.1e-26 90.4 0.0 3.2 3 0 0 3 3 3 2 AMP-binding enzyme Epimerase PF01370.21 KLO19193.1 - 5.3e-09 35.9 0.0 9.5e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO19193.1 - 0.013 14.5 0.0 0.03 13.3 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KLO19193.1 - 0.025 14.5 0.2 0.23 11.4 0.0 2.5 3 0 0 3 3 3 0 KR domain Semialdhyde_dh PF01118.24 KLO19193.1 - 0.034 14.6 0.0 0.16 12.4 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Dimerisation PF08100.11 KLO19193.1 - 0.057 13.4 0.1 0.18 11.8 0.1 2.0 1 0 0 1 1 1 0 Dimerisation domain PP-binding PF00550.25 KLO19193.1 - 0.087 13.2 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KLO19193.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase GMC_oxred_N PF00732.19 KLO19194.1 - 3e-59 200.8 0.0 5.4e-59 200.0 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO19194.1 - 2.8e-33 115.4 0.0 5e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KLO19194.1 - 4e-05 22.8 0.2 6.6e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KLO19194.1 - 6.4e-05 23.1 0.5 0.00021 21.5 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KLO19194.1 - 0.00011 21.6 0.2 0.02 14.2 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KLO19194.1 - 0.00023 20.9 1.7 0.00051 19.7 1.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO19194.1 - 0.00036 19.7 0.2 0.00061 19.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO19194.1 - 0.00085 18.6 0.1 0.0019 17.5 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO19194.1 - 0.0017 17.6 0.1 0.0028 16.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KLO19194.1 - 0.011 14.5 0.2 0.041 12.6 0.1 1.9 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 KLO19194.1 - 0.13 12.2 0.3 0.28 11.2 0.3 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 KLO19194.1 - 0.19 10.7 0.2 7.4 5.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A GMC_oxred_N PF00732.19 KLO19195.1 - 7.5e-55 186.4 0.0 1e-54 185.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KLO19195.1 - 1.4e-31 109.9 0.0 2.7e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KLO19195.1 - 8.6e-07 28.5 0.0 9.8e-06 25.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KLO19195.1 - 3.4e-05 23.1 0.1 5.1e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KLO19195.1 - 4e-05 23.4 0.6 0.00011 21.9 0.6 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO19195.1 - 0.00017 20.8 0.1 0.00037 19.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KLO19195.1 - 0.0003 20.1 0.1 0.00053 19.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KLO19195.1 - 0.00032 20.9 0.4 0.00067 19.8 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KLO19195.1 - 0.0005 19.4 0.1 0.12 11.6 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO19195.1 - 0.0015 17.3 0.0 0.0029 16.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KLO19195.1 - 0.0025 18.3 0.4 0.74 10.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KLO19195.1 - 0.0068 15.8 0.6 0.015 14.6 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KLO19195.1 - 0.048 13.7 0.2 0.085 12.8 0.2 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KLO19195.1 - 0.061 12.2 0.2 0.088 11.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 KLO19195.1 - 0.068 12.2 0.4 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Rtt106 PF08512.12 KLO19195.1 - 0.19 12.1 0.2 0.69 10.4 0.1 1.8 2 0 0 2 2 2 0 Histone chaperone Rttp106-like WD40 PF00400.32 KLO19196.1 - 5.7e-13 49.1 16.1 0.0003 21.5 0.2 6.7 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19196.1 - 2.1e-10 40.8 0.2 0.00075 19.8 0.0 4.1 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 KLO19196.1 - 0.00039 19.3 0.5 0.034 12.9 0.1 2.9 2 1 0 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 KLO19196.1 - 0.014 15.2 0.1 0.69 9.8 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KLO19196.1 - 4 7.5 5.9 8.2 6.5 0.2 3.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat zf-MYND PF01753.18 KLO19197.1 - 7.7e-10 38.7 9.7 2.4e-09 37.1 9.7 1.9 1 0 0 1 1 1 1 MYND finger FAA_hydrolase PF01557.18 KLO19198.1 - 3.7e-58 196.7 0.0 4.5e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 KLO19198.1 - 0.13 12.1 0.6 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 KH domain SAPS PF04499.15 KLO19199.1 - 1.2e-93 314.5 0.0 1.4e-93 314.3 0.0 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Adap_comp_sub PF00928.21 KLO19200.1 - 8.2e-86 287.6 0.0 1.1e-85 287.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KLO19200.1 - 1.8e-06 27.9 1.7 3.8e-06 26.9 1.7 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain VP7 PF00434.18 KLO19200.1 - 0.031 13.4 0.1 0.065 12.4 0.1 1.5 1 0 0 1 1 1 0 Glycoprotein VP7 DUF5618 PF18498.1 KLO19200.1 - 0.078 13.2 0.2 0.25 11.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) DUF11 PF01345.18 KLO19200.1 - 0.21 11.9 2.9 0.25 11.6 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF11 Lipase_GDSL PF00657.22 KLO19201.1 - 1.4e-06 28.4 0.1 1.6e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KLO19201.1 - 3.9e-06 27.4 0.1 5.5e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF572 PF04502.13 KLO19202.1 - 2.7e-83 280.4 9.2 3e-83 280.2 9.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 KLO19202.1 - 0.019 14.9 0.8 0.73 9.8 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif FinO_N PF12602.8 KLO19202.1 - 0.054 13.8 1.6 0.19 12.1 1.6 2.1 1 1 0 1 1 1 0 Fertility inhibition protein N terminal PI3_PI4_kinase PF00454.27 KLO19203.1 - 3.9e-34 118.6 0.0 8.5e-32 110.9 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KLO19203.1 - 1.1e-19 70.6 0.0 3.1e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) RMI1_C PF16099.5 KLO19203.1 - 0.097 12.5 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold DUF4135 PF13575.6 KLO19203.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) RdRP PF05183.12 KLO19204.1 - 2.3e-160 535.1 0.0 2.8e-160 534.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sybindin PF04099.12 KLO19205.1 - 2.1e-38 131.5 0.0 2.3e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KLO19205.1 - 4e-09 36.7 0.0 4.2e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Collagen_mid PF15984.5 KLO19205.1 - 0.041 13.6 0.3 0.056 13.2 0.3 1.1 1 0 0 1 1 1 0 Bacterial collagen, middle region Peptidase_M28 PF04389.17 KLO19206.1 - 6.2e-37 127.2 1.2 2.2e-36 125.4 0.2 2.2 2 1 0 2 2 2 1 Peptidase family M28 DUF1415 PF07209.12 KLO19207.1 - 0.035 13.8 0.2 0.076 12.8 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1415) DivIVA PF05103.13 KLO19207.1 - 0.8 9.8 8.3 0.095 12.8 2.3 2.1 2 1 0 2 2 2 0 DivIVA protein Com_YlbF PF06133.11 KLO19207.1 - 2.2 8.9 10.8 2.5 8.7 6.0 2.7 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA OmpH PF03938.14 KLO19207.1 - 4.2 7.7 12.6 1.1 9.5 6.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Methyltransf_32 PF13679.6 KLO19208.1 - 5.9e-25 88.1 0.1 1.2e-24 87.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO19208.1 - 0.00019 21.2 0.0 0.00043 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO19208.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MerR-DNA-bind PF09278.11 KLO19208.1 - 0.019 15.5 0.1 0.05 14.2 0.1 1.7 1 0 0 1 1 1 0 MerR, DNA binding TRM13 PF05206.14 KLO19208.1 - 0.029 13.9 0.3 9.8 5.6 0.1 3.0 3 1 0 3 3 3 0 Methyltransferase TRM13 Methyltransf_25 PF13649.6 KLO19208.1 - 0.084 13.6 0.0 0.24 12.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KLO19208.1 - 0.14 12.9 0.3 0.42 11.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain NAD_binding_10 PF13460.6 KLO19209.1 - 3.5e-31 108.5 0.0 4.2e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KLO19209.1 - 0.00016 21.3 0.1 0.00029 20.5 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Ldh_1_N PF00056.23 KLO19209.1 - 0.0042 17.2 0.2 0.0066 16.5 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 KLO19209.1 - 0.0073 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KLO19209.1 - 0.042 14.3 0.1 0.066 13.7 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KLO19209.1 - 0.17 11.9 0.1 0.7 9.9 0.1 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DapB_N PF01113.20 KLO19209.1 - 0.19 11.9 0.2 0.44 10.7 0.1 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TPP_enzyme_N PF02776.18 KLO19210.1 - 2.8e-55 186.6 0.2 2.6e-54 183.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KLO19210.1 - 1.4e-47 161.3 0.4 8.3e-46 155.5 0.3 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KLO19210.1 - 1.9e-38 131.3 0.4 4.5e-38 130.1 0.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CRR7 PF12095.8 KLO19211.1 - 0.014 15.8 0.3 2.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 His_Phos_1 PF00300.22 KLO19212.1 - 7.6e-37 126.9 0.4 3.3e-36 124.8 0.4 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LysR_substrate PF03466.20 KLO19212.1 - 0.0066 15.8 0.1 0.012 14.9 0.1 1.4 2 0 0 2 2 2 1 LysR substrate binding domain CBF PF03914.17 KLO19213.1 - 1.1e-44 152.5 0.0 1.1e-44 152.5 0.0 3.8 3 1 0 3 3 3 1 CBF/Mak21 family BUD22 PF09073.10 KLO19213.1 - 0.0012 18.3 72.6 0.054 12.8 26.3 3.5 3 0 0 3 3 3 3 BUD22 Cnd1 PF12717.7 KLO19213.1 - 0.0035 17.4 0.1 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KLO19213.1 - 0.0051 15.4 0.1 0.038 12.6 0.0 2.0 2 0 0 2 2 2 1 Adaptin N terminal region PUL PF08324.11 KLO19214.1 - 2.4e-42 145.1 0.0 3.2e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KLO19214.1 - 2.8e-42 143.5 0.1 5.4e-42 142.6 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KLO19214.1 - 9e-31 105.5 14.6 1.8e-06 28.5 0.1 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 KLO19214.1 - 0.00018 21.5 0.0 0.27 11.3 0.0 3.0 1 1 3 4 4 4 3 Ciliary BBSome complex subunit 2, middle region HORMA PF02301.18 KLO19215.1 - 1.3e-63 214.4 0.5 3e-63 213.2 0.0 1.8 2 0 0 2 2 2 1 HORMA domain PHD PF00628.29 KLO19215.1 - 8e-08 32.1 7.4 1.3e-07 31.3 7.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 KLO19215.1 - 0.0065 16.1 0.1 0.019 14.6 0.1 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 KLO19215.1 - 0.11 12.4 2.6 0.24 11.4 2.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PigN PF04987.14 KLO19216.1 - 1.7e-123 412.9 23.9 2.2e-123 412.5 23.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KLO19216.1 - 4e-09 36.5 0.8 8.2e-07 28.9 0.8 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KLO19216.1 - 2.1e-06 27.4 0.2 2.9e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KLO19216.1 - 0.0028 17.1 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Avian_gp85 PF03708.14 KLO19216.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Avian retrovirus envelope protein, gp85 Na_Ca_ex PF01699.24 KLO19217.1 - 1.9e-40 138.2 35.0 6.7e-23 81.3 16.3 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Methyltransf_25 PF13649.6 KLO19218.1 - 4.5e-07 30.5 0.0 0.002 18.8 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KLO19218.1 - 0.026 15.1 0.0 1.6 9.4 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KLO19218.1 - 0.09 13.5 0.0 0.39 11.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain GIY-YIG PF01541.24 KLO19219.1 - 0.00085 19.6 2.9 38 4.7 0.6 6.2 1 1 2 3 3 3 0 GIY-YIG catalytic domain T4bSS_IcmS PF12608.8 KLO19219.1 - 0.006 16.9 0.0 13 6.2 0.0 3.9 1 1 1 2 2 2 2 Type IVb secretion, IcmS, effector-recruitment DUF4309 PF14172.6 KLO19219.1 - 0.0076 16.3 18.9 14 5.7 0.4 6.9 1 1 3 4 4 4 3 Domain of unknown function (DUF4309) HigB_toxin PF09907.9 KLO19219.1 - 0.023 14.9 16.5 27 5.1 0.1 6.0 1 1 4 6 6 6 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 3D PF06725.11 KLO19219.1 - 4.2 7.6 13.7 1.1e+02 3.1 0.1 6.4 1 1 9 10 10 10 0 3D domain Gtr1_RagA PF04670.12 KLO19220.1 - 1.5e-87 292.8 0.0 1.9e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KLO19220.1 - 1.2e-08 35.2 0.0 2.7e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KLO19220.1 - 3e-08 33.4 0.0 5.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KLO19220.1 - 9.3e-07 28.5 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KLO19220.1 - 4.7e-06 26.7 0.0 9.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KLO19220.1 - 0.018 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RuvB_N PF05496.12 KLO19220.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 KLO19220.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KLO19220.1 - 0.085 12.6 0.1 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KLO19220.1 - 0.29 10.3 2.3 9.5 5.3 0.4 2.6 2 1 0 3 3 3 0 G-protein alpha subunit zf-CCHC_2 PF13696.6 KLO19221.1 - 2.9e-27 94.1 12.0 1.4e-10 40.7 0.9 3.5 3 0 0 3 3 3 3 Zinc knuckle CwfJ_C_1 PF04677.15 KLO19221.1 - 3.1e-26 91.6 0.0 5.3e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KLO19221.1 - 2.4e-15 57.2 0.0 5.9e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 KLO19221.1 - 2.3e-09 36.9 6.4 0.0013 18.7 0.1 3.7 3 0 0 3 3 3 2 Zinc knuckle Metallophos PF00149.28 KLO19221.1 - 0.03 14.8 0.0 0.056 13.9 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase zinc-ribbons_6 PF07191.12 KLO19221.1 - 0.92 9.5 10.5 13 5.9 3.7 3.1 1 1 1 2 2 2 0 zinc-ribbons Zn_ribbon_SprT PF17283.2 KLO19221.1 - 2.9 7.9 7.6 28 4.7 0.3 3.2 2 1 1 3 3 3 0 SprT-like zinc ribbon domain TRAF6_Z2 PF18048.1 KLO19221.1 - 3.4 7.8 5.7 58 3.9 0.1 3.3 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Aminotran_1_2 PF00155.21 KLO19222.1 - 8.6e-32 110.7 0.0 1e-31 110.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Arginase PF00491.21 KLO19223.1 - 4e-79 266.0 0.2 4.7e-79 265.8 0.2 1.0 1 0 0 1 1 1 1 Arginase family DHBP_synthase PF00926.19 KLO19224.1 - 7.1e-85 283.4 0.1 8.2e-85 283.2 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Zn_clus PF00172.18 KLO19225.1 - 1.2e-06 28.5 13.1 1.9e-06 27.9 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 KLO19226.1 - 1.6e-43 148.5 0.2 3.2e-43 147.5 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KLO19226.1 - 1.5e-36 125.5 0.0 2.8e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KLO19226.1 - 1.1e-25 89.7 0.0 2e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KLO19226.1 - 3.4e-16 59.7 0.0 6.5e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KLO19226.1 - 0.0036 17.0 0.1 0.014 15.1 0.1 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal F-box-like PF12937.7 KLO19227.1 - 0.11 12.4 1.8 0.32 10.9 1.8 1.9 1 0 0 1 1 1 0 F-box-like Ins_P5_2-kin PF06090.12 KLO19228.1 - 1e-73 248.7 0.0 1.2e-73 248.5 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase YdiH PF15930.5 KLO19228.1 - 0.12 12.6 0.0 0.73 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function Kinesin PF00225.23 KLO19229.1 - 7.7e-98 327.5 8.6 2.3e-55 187.9 0.0 3.6 4 0 0 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 KLO19229.1 - 3.9e-21 75.6 0.0 1.9e-20 73.3 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding Fib_alpha PF08702.10 KLO19229.1 - 0.0038 17.4 2.9 0.0038 17.4 2.9 12.1 8 5 3 12 12 12 4 Fibrinogen alpha/beta chain family adh_short_C2 PF13561.6 KLO19230.1 - 6.4e-61 205.9 0.2 7.6e-61 205.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO19230.1 - 1.3e-48 165.1 0.1 2.8e-48 164.0 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KLO19230.1 - 7.2e-16 58.6 0.1 1.2e-15 57.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KLO19230.1 - 7.3e-07 28.6 0.0 9.1e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KLO19230.1 - 2.4e-06 27.2 0.0 3.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ThiF PF00899.21 KLO19230.1 - 0.024 14.0 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 ThiF family GDP_Man_Dehyd PF16363.5 KLO19230.1 - 0.14 11.5 0.0 6.4 6.1 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ATP12 PF07542.11 KLO19230.1 - 0.15 12.1 0.1 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 ATP12 chaperone protein Abhydrolase_1 PF00561.20 KLO19231.1 - 5.1e-13 49.3 0.0 9.2e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO19231.1 - 3.2e-11 44.2 0.0 3.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO19231.1 - 9.1e-09 34.9 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KLO19231.1 - 7.1e-07 28.5 0.0 1e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 KLO19231.1 - 4.7e-05 22.4 0.0 7.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Methyltransf_25 PF13649.6 KLO19232.1 - 3.4e-07 30.9 0.0 0.00034 21.3 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain DUF5612 PF18462.1 KLO19233.1 - 0.0066 16.2 0.3 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5612) MerB PF03243.15 KLO19233.1 - 0.13 12.4 0.1 0.48 10.6 0.0 1.9 3 0 0 3 3 3 0 Alkylmercury lyase GATA PF00320.27 KLO19234.1 - 8.5e-13 47.7 6.7 1.9e-12 46.5 6.7 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 KLO19234.1 - 0.00013 21.9 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KLO19234.1 - 0.018 15.3 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.7 KLO19234.1 - 0.039 14.2 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 PAS domain TOH_N PF12549.8 KLO19234.1 - 0.23 11.3 2.3 1.2 9.1 2.3 2.3 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal p450 PF00067.22 KLO19235.1 - 3.2e-74 250.4 0.0 4e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Psb28 PF03912.14 KLO19235.1 - 0.19 12.0 0.1 0.37 11.1 0.1 1.4 1 0 0 1 1 1 0 Psb28 protein p450 PF00067.22 KLO19236.1 - 8.1e-75 252.3 0.0 1.1e-74 251.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 tRNA_Me_trans PF03054.16 KLO19237.1 - 8.4e-101 337.3 0.0 9.4e-101 337.1 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase UPF1_Zn_bind PF09416.10 KLO19238.1 - 6.7e-69 230.7 2.1 6.7e-69 230.7 2.1 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KLO19238.1 - 2.5e-58 197.0 0.0 4.6e-58 196.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KLO19238.1 - 1e-36 127.1 9.0 2.3e-20 73.5 0.7 3.0 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KLO19238.1 - 3e-35 120.3 0.0 7.3e-35 119.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KLO19238.1 - 2.7e-13 50.1 2.0 3.9e-12 46.3 2.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO19238.1 - 2.6e-10 40.8 1.6 1.2e-09 38.7 1.6 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KLO19238.1 - 2.9e-08 33.4 0.1 9.2e-07 28.4 0.0 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KLO19238.1 - 5.6e-06 26.5 0.1 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KLO19238.1 - 8.1e-05 22.6 0.5 0.00023 21.1 0.5 1.8 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 KLO19238.1 - 0.00023 21.0 0.2 0.18 11.5 0.0 3.5 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KLO19238.1 - 0.0026 17.3 0.4 0.0076 15.8 0.4 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_10 PF12846.7 KLO19238.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PIF1 PF05970.14 KLO19238.1 - 0.013 14.7 0.1 0.92 8.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase SRP54 PF00448.22 KLO19238.1 - 0.014 15.0 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DEAD PF00270.29 KLO19238.1 - 0.024 14.4 0.2 0.047 13.4 0.2 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase ATPase PF06745.13 KLO19238.1 - 0.029 13.7 0.2 0.15 11.4 0.0 2.1 2 1 0 2 2 2 0 KaiC AAA_22 PF13401.6 KLO19238.1 - 0.041 14.2 0.2 0.16 12.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KLO19238.1 - 0.044 13.2 0.1 0.089 12.2 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 KLO19238.1 - 0.095 13.1 0.2 0.28 11.6 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KLO19238.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HSP20 PF00011.21 KLO19239.1 - 2.3e-16 59.8 0.1 7.1e-16 58.2 0.1 1.7 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KLO19239.1 - 1.5e-13 50.1 0.0 2.8e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 KLO19239.1 - 0.013 15.5 0.1 5.4 7.2 0.0 2.3 2 0 0 2 2 2 0 FKBP26_C-terminal DUF4140 PF13600.6 KLO19239.1 - 0.024 15.0 0.1 4.6 7.7 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) GvpH PF05455.11 KLO19239.1 - 0.026 14.6 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 GvpH Abhydrolase_6 PF12697.7 KLO19240.1 - 2.1e-13 51.4 0.2 3.7e-13 50.6 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.22 KLO19241.1 - 7.2e-73 245.9 0.0 9.4e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KLO19242.1 - 4.5e-22 78.5 82.8 2.4e-16 59.6 49.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CENP-C_C PF11699.8 KLO19245.1 - 1.8e-25 89.0 0.2 3.1e-25 88.2 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KLO19245.1 - 3.2e-05 23.6 0.0 9.4e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KLO19245.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain CDC45 PF02724.14 KLO19245.1 - 6.4 4.9 6.0 12 4.0 6.0 1.3 1 0 0 1 1 1 0 CDC45-like protein HSP20 PF00011.21 KLO19246.1 - 2.3e-15 56.6 0.1 3.3e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KLO19246.1 - 6.3e-13 48.1 0.1 2.1e-12 46.4 0.1 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 KLO19246.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 GvpH FKBP26_C PF18046.1 KLO19246.1 - 0.14 12.3 0.0 8.3 6.6 0.0 2.3 2 0 0 2 2 2 0 FKBP26_C-terminal SKIP_SNW PF02731.15 KLO19247.1 - 3.8e-72 241.2 1.2 3.8e-72 241.2 1.2 2.7 3 0 0 3 3 3 1 SKIP/SNW domain BTB PF00651.31 KLO19249.1 - 1.3e-05 25.4 1.5 2.8e-05 24.3 0.3 2.1 2 1 0 2 2 2 1 BTB/POZ domain DUF4611 PF15387.6 KLO19249.1 - 0.21 11.8 0.0 0.49 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2015 PF09435.10 KLO19250.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) Zn_clus PF00172.18 KLO19251.1 - 0.035 14.2 7.3 0.068 13.3 7.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO19252.1 - 0.27 11.4 9.9 0.5 10.5 9.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP20 PF00011.21 KLO19254.1 - 7.2e-16 58.2 0.1 5.2e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KLO19254.1 - 1.2e-12 47.1 0.1 4.2e-12 45.4 0.1 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 KLO19254.1 - 0.047 13.8 0.0 8.1 6.6 0.0 2.3 2 0 0 2 2 2 0 FKBP26_C-terminal DUF4140 PF13600.6 KLO19254.1 - 0.1 13.0 0.2 5.3 7.5 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Zn_clus PF00172.18 KLO19255.1 - 0.0051 16.9 13.9 0.0093 16.1 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO19256.1 - 0.94 9.7 14.5 0.2 11.8 9.5 2.0 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Tuberin PF03542.16 KLO19259.1 - 0.078 12.1 0.3 0.11 11.6 0.3 1.1 1 0 0 1 1 1 0 Tuberin PAP_assoc PF03828.19 KLO19261.1 - 1.6e-18 66.6 0.3 5.4e-18 65.0 0.1 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KLO19261.1 - 7.8e-09 35.7 0.0 1.8e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.6 KLO19261.1 - 0.0036 17.5 0.0 0.013 15.6 0.0 2.0 1 0 0 1 1 1 1 DNA polymerase beta palm TAP42 PF04177.12 KLO19262.1 - 2.9e-81 273.1 3.5 3.4e-81 272.9 3.5 1.0 1 0 0 1 1 1 1 TAP42-like family Ras PF00071.22 KLO19263.1 - 2.8e-56 189.6 0.2 3.6e-56 189.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO19263.1 - 1.8e-35 121.7 0.1 2.7e-35 121.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO19263.1 - 2e-14 53.4 0.2 2.5e-14 53.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KLO19263.1 - 9.8e-07 28.4 0.2 1.6e-06 27.7 0.2 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KLO19263.1 - 2.2e-05 24.1 0.4 0.00021 20.9 0.2 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KLO19263.1 - 2.6e-05 24.3 0.0 5.3e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KLO19263.1 - 0.00011 21.7 0.2 0.00014 21.3 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KLO19263.1 - 0.0002 21.3 0.2 0.34 10.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KLO19263.1 - 0.019 14.5 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KLO19263.1 - 0.034 13.9 1.1 0.26 11.0 1.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KLO19263.1 - 0.057 12.9 0.3 1.9 8.0 0.3 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B MTHFR PF02219.17 KLO19264.1 - 4.3e-105 351.1 0.0 5.8e-105 350.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase WD40 PF00400.32 KLO19265.1 - 6.3e-10 39.5 11.7 0.0088 16.9 0.2 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19265.1 - 1.4e-09 38.1 0.0 0.0014 18.9 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KLO19265.1 - 0.029 14.3 0.4 3.8 7.6 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Transket_pyr PF02779.24 KLO19266.1 - 2.5e-39 134.8 0.1 3.5e-39 134.3 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KLO19266.1 - 3.7e-29 101.1 0.0 1.8e-28 98.9 0.0 2.1 2 1 0 2 2 2 1 Transketolase, C-terminal domain POT1PC PF16686.5 KLO19268.1 - 2.3e-11 43.8 0.6 0.0035 17.2 0.0 3.7 3 0 0 3 3 3 3 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KLO19268.1 - 9.1e-05 22.3 0.0 0.00026 20.9 0.0 1.8 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 KLO19268.1 - 0.065 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Replication protein A OB domain P_proprotein PF01483.20 KLO19269.1 - 1.4e-27 95.5 0.4 2.7e-27 94.6 0.4 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8 PF00082.22 KLO19269.1 - 2.9e-27 95.7 2.1 6.1e-27 94.6 2.1 1.5 1 1 0 1 1 1 1 Subtilase family MCM PF00493.23 KLO19270.1 - 8.4e-107 355.4 0.0 5.5e-106 352.7 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KLO19270.1 - 2.2e-29 101.8 0.4 3.9e-29 101.0 0.4 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KLO19270.1 - 5.6e-20 71.5 1.4 5.6e-20 71.5 1.4 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KLO19270.1 - 4.4e-19 69.0 4.0 9e-19 68.0 3.2 2.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 KLO19270.1 - 6e-08 32.8 0.4 7.3e-07 29.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KLO19270.1 - 9.2e-08 31.7 0.1 1.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 KLO19270.1 - 0.0043 17.7 3.0 0.013 16.1 0.1 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 KLO19270.1 - 0.005 16.7 0.0 0.018 14.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KLO19270.1 - 0.037 13.9 1.8 0.065 13.1 0.1 2.3 2 0 0 2 2 2 0 AAA lid domain AAA PF00004.29 KLO19270.1 - 0.076 13.4 1.2 1.1 9.7 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KLO19270.1 - 0.089 12.5 0.1 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 KLO19270.1 - 0.14 12.5 1.4 3 8.2 0.0 3.2 3 1 0 4 4 4 0 AAA ATPase domain DNA_methylase PF00145.17 KLO19271.1 - 4.1e-52 177.6 0.0 1.5e-51 175.7 0.0 1.9 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KLO19271.1 - 3.2e-14 52.8 0.0 5.5e-11 42.4 0.0 2.8 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 KLO19271.1 - 4.8e-11 42.9 0.0 9.1e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Cons_hypoth95 PF03602.15 KLO19271.1 - 0.15 11.7 0.1 0.58 9.8 0.0 2.1 2 1 0 2 2 2 0 Conserved hypothetical protein 95 HMGL-like PF00682.19 KLO19272.1 - 1e-75 254.7 0.0 1.5e-75 254.2 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KLO19272.1 - 1.3e-45 154.6 0.2 2.5e-23 82.5 0.0 2.6 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain Thiamine_BP PF01910.17 KLO19273.1 - 1.5e-26 92.1 0.0 1.8e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Ykof PF07615.11 KLO19273.1 - 0.0012 19.2 0.0 0.0017 18.8 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family DUF2102 PF09875.9 KLO19273.1 - 0.096 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) VRR_NUC PF08774.11 KLO19274.1 - 1e-21 77.0 0.0 3.5e-21 75.3 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain PBP_N PF17093.5 KLO19274.1 - 1.5 9.0 4.3 40 4.5 0.1 2.8 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus bVLRF1 PF18826.1 KLO19275.1 - 8.3e-65 217.2 0.0 1.3e-64 216.5 0.0 1.3 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Head-tail_con PF12236.8 KLO19275.1 - 0.07 11.6 0.1 0.22 9.9 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage head to tail connecting protein PMM PF03332.13 KLO19276.1 - 2.3e-107 357.8 1.3 2.7e-107 357.5 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.13 KLO19276.1 - 0.022 14.3 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 KLO19276.1 - 0.034 13.9 0.0 0.31 10.7 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAS-barrel PF09378.10 KLO19276.1 - 0.06 13.5 0.1 0.72 10.1 0.0 2.2 1 1 1 2 2 2 0 HAS barrel domain zf-C2H2_4 PF13894.6 KLO19277.1 - 0.0057 17.4 12.0 3.6 8.7 1.9 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger Myb_DNA-bind_7 PF15963.5 KLO19277.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Myb DNA-binding like zf-C2H2_aberr PF17017.5 KLO19277.1 - 0.13 12.4 3.6 1.1 9.4 0.2 2.2 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2 PF00096.26 KLO19277.1 - 0.17 12.4 13.4 0.37 11.3 0.5 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type Zap1_zf2 PF18217.1 KLO19277.1 - 0.89 9.6 8.2 0.083 12.9 1.7 2.4 2 0 0 2 2 2 0 Zap1 zinc finger 2 NUDIX PF00293.28 KLO19278.1 - 6.6e-11 42.4 0.0 1e-10 41.8 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain Vma12 PF11712.8 KLO19279.1 - 1.2e-08 35.2 0.6 1.2e-08 35.2 0.6 2.0 2 1 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Atx10homo_assoc PF09759.9 KLO19280.1 - 5.2e-26 90.6 0.3 2.7e-24 85.1 0.0 2.8 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain Leo1 PF04004.13 KLO19281.1 - 8e-46 155.9 0.1 8e-46 155.9 0.1 2.3 3 0 0 3 3 3 1 Leo1-like protein Mpp10 PF04006.12 KLO19281.1 - 0.36 9.2 41.4 0.081 11.4 16.5 2.1 2 0 0 2 2 2 0 Mpp10 protein DUF4160 PF13711.6 KLO19283.1 - 0.11 12.9 0.0 3.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) Cnd2 PF05786.14 KLO19285.1 - 3.2e-190 634.6 10.7 3.2e-190 634.6 10.7 1.6 2 0 0 2 2 2 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KLO19285.1 - 0.098 12.9 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal SQHop_cyclase_N PF13249.6 KLO19286.1 - 1.5e-50 171.9 0.1 4.1e-38 131.1 0.0 3.6 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KLO19286.1 - 2.1e-46 158.5 2.3 7.1e-46 156.8 0.6 2.3 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KLO19286.1 - 5.7e-32 109.1 9.9 3.7e-09 36.2 0.1 6.2 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KLO19286.1 - 2e-08 33.6 0.4 0.0023 17.0 0.2 4.0 3 1 2 5 5 5 2 A-macroglobulin TED domain Pec_lyase PF09492.10 KLO19286.1 - 0.016 14.6 0.1 10 5.4 0.0 3.5 3 1 1 4 4 4 0 Pectic acid lyase AAA PF00004.29 KLO19287.1 - 1.8e-97 322.9 0.0 1.4e-47 161.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KLO19287.1 - 1.3e-24 85.7 4.4 2.4e-11 43.3 0.4 2.8 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KLO19287.1 - 4e-20 71.8 0.6 1.1e-19 70.3 0.6 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KLO19287.1 - 2.2e-14 53.5 0.0 1.3e-05 25.0 0.0 3.6 4 1 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KLO19287.1 - 7.1e-14 52.3 0.0 1.6e-07 31.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KLO19287.1 - 7.1e-12 45.7 0.0 5.3e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 KLO19287.1 - 1.5e-11 43.9 0.0 3.1e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 KLO19287.1 - 4e-11 43.1 0.3 3.7e-05 23.7 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KLO19287.1 - 2.8e-10 40.8 0.0 0.00063 20.2 0.0 4.1 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 KLO19287.1 - 2.5e-09 36.8 0.4 0.0015 17.8 0.0 3.0 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_22 PF13401.6 KLO19287.1 - 2.6e-09 37.5 0.4 0.043 14.1 0.0 4.5 3 2 1 4 4 3 2 AAA domain IstB_IS21 PF01695.17 KLO19287.1 - 3.8e-07 30.0 0.0 0.024 14.4 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KLO19287.1 - 4.1e-07 29.6 0.3 0.028 13.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KLO19287.1 - 5.2e-07 30.3 0.0 0.02 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KLO19287.1 - 7e-07 28.8 0.1 0.19 11.0 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_14 PF13173.6 KLO19287.1 - 8.7e-07 29.0 0.0 0.019 15.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KLO19287.1 - 1.3e-06 28.7 0.0 0.019 15.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 KLO19287.1 - 5.4e-06 26.0 0.0 0.019 14.5 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KLO19287.1 - 1.1e-05 24.7 0.1 0.01 15.0 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 KLO19287.1 - 1.4e-05 25.7 0.0 0.14 12.7 0.0 3.8 3 1 0 3 3 2 1 ABC transporter Vps4_C PF09336.10 KLO19287.1 - 1.8e-05 24.7 0.1 0.00039 20.4 0.0 3.0 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_28 PF13521.6 KLO19287.1 - 2e-05 24.9 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KLO19287.1 - 2.2e-05 24.2 0.0 0.38 10.4 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 KLO19287.1 - 2.7e-05 23.8 2.0 1.3 8.6 0.1 3.7 2 2 1 3 3 3 2 AAA domain AAA_24 PF13479.6 KLO19287.1 - 2.9e-05 23.9 0.0 0.43 10.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain Bac_DnaA PF00308.18 KLO19287.1 - 8.5e-05 22.5 0.0 0.37 10.6 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein PhoH PF02562.16 KLO19287.1 - 0.00011 21.8 0.3 0.47 9.9 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein DUF815 PF05673.13 KLO19287.1 - 0.0002 20.6 0.0 0.045 12.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.6 KLO19287.1 - 0.00025 21.5 0.0 0.74 10.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KLO19287.1 - 0.00031 20.7 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KLO19287.1 - 0.00034 20.5 0.0 0.92 9.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KLO19287.1 - 0.00034 20.6 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KLO19287.1 - 0.00039 20.2 0.0 0.27 10.9 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KLO19287.1 - 0.00083 18.7 0.0 0.47 9.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 KLO19287.1 - 0.00086 19.2 0.0 1.4 8.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KLO19287.1 - 0.0024 17.6 0.9 2.1 8.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 KLO19287.1 - 0.0031 17.8 1.8 3.7 7.9 0.0 3.9 4 1 0 5 5 3 1 AAA domain Zeta_toxin PF06414.12 KLO19287.1 - 0.0035 16.6 0.0 2.4 7.4 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin ATPase_2 PF01637.18 KLO19287.1 - 0.0042 17.0 0.1 4.5 7.1 0.0 3.1 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KLO19287.1 - 0.0047 16.9 0.2 1.1 9.2 0.0 3.0 3 1 0 3 3 2 1 NACHT domain Sigma54_activ_2 PF14532.6 KLO19287.1 - 0.0057 16.8 0.0 6.4 6.9 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 KLO19287.1 - 0.0069 15.6 0.0 0.64 9.2 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain UFD1 PF03152.14 KLO19287.1 - 0.0092 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 NTPase_1 PF03266.15 KLO19287.1 - 0.021 14.8 0.4 4 7.3 0.0 3.4 3 0 0 3 3 3 0 NTPase T2SSE PF00437.20 KLO19287.1 - 0.023 13.8 0.0 0.81 8.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.16 KLO19287.1 - 0.045 13.1 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin PF02224.18 KLO19287.1 - 0.055 13.2 0.0 8.1 6.1 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Amidase PF01425.21 KLO19288.1 - 9.5e-108 361.0 0.8 1.6e-107 360.3 0.8 1.3 1 1 0 1 1 1 1 Amidase SbsC_C PF18058.1 KLO19288.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 SbsC C-terminal domain BRAP2 PF07576.12 KLO19289.1 - 1.6e-29 102.0 0.1 3e-29 101.1 0.1 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KLO19289.1 - 2.2e-20 72.7 3.1 6.9e-20 71.1 3.2 1.8 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KLO19289.1 - 1.1e-08 35.2 9.3 1.1e-08 35.2 9.3 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KLO19289.1 - 1.9e-06 27.6 9.3 4.5e-06 26.4 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KLO19289.1 - 4.1e-06 26.4 3.6 1.2e-05 24.9 3.6 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KLO19289.1 - 9.7e-06 25.8 5.8 2.7e-05 24.4 5.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KLO19289.1 - 4.4e-05 23.4 5.9 4.4e-05 23.4 5.9 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KLO19289.1 - 5.1e-05 23.1 7.1 0.00013 21.8 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO19289.1 - 0.00046 20.0 6.4 0.00046 20.0 6.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KLO19289.1 - 0.0021 18.0 6.6 0.0021 18.0 6.6 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KLO19289.1 - 0.0063 16.5 3.6 0.016 15.3 3.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KLO19289.1 - 0.019 14.7 6.2 0.052 13.3 6.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KLO19289.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3685 PF12452.8 KLO19289.1 - 0.36 10.5 2.7 0.61 9.8 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) DUF2968 PF11180.8 KLO19289.1 - 0.43 10.2 17.1 0.2 11.3 6.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) zf-C3HC4_4 PF15227.6 KLO19289.1 - 0.49 10.6 6.1 2.2 8.5 6.2 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING UPF0242 PF06785.11 KLO19289.1 - 0.91 9.6 28.0 1.5 8.9 7.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc42p PF11544.8 KLO19289.1 - 0.95 9.5 14.7 0.46 10.5 0.8 3.2 1 1 2 3 3 3 0 Spindle pole body component Spc42p AAA_13 PF13166.6 KLO19289.1 - 1.2 7.7 17.2 1.8 7.1 17.2 1.1 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 KLO19289.1 - 1.2 8.6 8.9 2.1 7.8 8.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TerY_C PF15616.6 KLO19289.1 - 3.6 7.7 13.6 2.9 8.0 3.8 2.6 1 1 1 2 2 2 0 TerY-C metal binding domain DUF4407 PF14362.6 KLO19289.1 - 4.7 6.5 11.8 7.3 5.9 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Laminin_II PF06009.12 KLO19289.1 - 6.1 6.9 14.0 5.4 7.0 10.1 2.2 1 1 1 2 2 2 0 Laminin Domain II Lipoprotein_20 PF13942.6 KLO19289.1 - 8.8 6.2 18.4 2 8.3 3.0 2.8 1 1 2 3 3 3 0 YfhG lipoprotein Actin PF00022.19 KLO19290.1 - 5.4e-34 117.5 0.0 3e-33 115.0 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KLO19290.1 - 7.8e-06 24.9 0.0 1.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein WD40 PF00400.32 KLO19291.1 - 2.5e-23 81.9 6.7 1.2e-05 26.0 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19291.1 - 1.4e-05 25.3 0.2 0.056 13.8 0.0 3.6 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1604 PF07713.13 KLO19292.1 - 1.2e-39 134.0 2.2 3.7e-39 132.4 1.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KLO19292.1 - 0.00015 21.5 0.1 0.00015 21.5 0.1 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KLO19292.1 - 0.016 15.3 0.3 0.21 11.7 0.3 3.0 1 1 0 1 1 1 0 G-patch domain AA_permease PF00324.21 KLO19293.1 - 1.5e-120 403.1 33.1 1.7e-120 402.9 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KLO19293.1 - 1e-33 116.9 38.1 1.2e-33 116.6 38.1 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_12 PF08242.12 KLO19294.1 - 2.2e-12 47.6 0.0 5.7e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO19294.1 - 3.8e-12 46.7 0.0 8.4e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KLO19294.1 - 5.7e-10 39.3 0.0 9.6e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO19294.1 - 2.8e-09 37.5 0.0 6.9e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO19294.1 - 8.5e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KLO19294.1 - 0.00068 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NNMT_PNMT_TEMT PF01234.17 KLO19294.1 - 0.0052 16.0 0.0 0.096 11.9 0.0 2.0 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family MTS PF05175.14 KLO19294.1 - 0.0064 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KLO19294.1 - 0.0076 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KLO19294.1 - 0.15 13.1 0.0 0.29 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RhoGEF PF00621.20 KLO19295.1 - 2.9e-64 216.6 0.7 1.7e-31 109.9 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.22 KLO19295.1 - 1.3e-61 208.6 0.0 2.6e-61 207.6 0.0 1.5 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KLO19295.1 - 3.9e-16 59.4 0.0 9.2e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KLO19295.1 - 0.0016 18.4 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_16 PF17838.1 KLO19295.1 - 0.024 14.5 0.1 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 PH domain PH PF00169.29 KLO19295.1 - 0.036 14.6 0.0 0.24 11.9 0.0 2.5 2 1 0 2 2 2 0 PH domain Bud13 PF09736.9 KLO19296.1 - 1.3e-54 184.6 8.1 1.3e-54 184.6 8.1 2.3 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex PROL5-SMR PF15621.6 KLO19296.1 - 0.18 12.3 2.6 15 6.2 0.8 2.3 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Pkinase_Tyr PF07714.17 KLO19297.1 - 3e-09 36.5 0.0 9e-09 35.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO19297.1 - 3e-07 30.1 0.0 8.8e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KLO19298.1 - 2.9e-48 160.8 21.0 3.1e-07 31.0 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 KLO19298.1 - 4.7e-43 147.3 0.0 7.3e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO19298.1 - 3.8e-42 144.5 0.0 5.8e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ANAPC4_WD40 PF12894.7 KLO19298.1 - 4.5e-16 58.9 0.3 0.0069 16.7 0.0 6.0 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO19298.1 - 3e-06 26.4 0.5 1.5 7.7 0.0 6.0 2 2 5 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KLO19298.1 - 8.1e-06 25.4 0.0 1.5 8.1 0.0 4.3 5 1 1 6 6 6 3 WD40-like domain PD40 PF07676.12 KLO19298.1 - 0.00098 19.0 0.0 8.8 6.4 0.0 4.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KLO19298.1 - 0.011 14.4 0.3 0.11 11.1 0.0 2.6 4 1 0 4 4 4 0 Nucleoporin Nup120/160 Kinase-like PF14531.6 KLO19298.1 - 0.015 14.6 0.0 0.088 12.1 0.0 1.9 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KLO19298.1 - 0.023 13.5 0.1 0.034 12.9 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Nucleoporin_N PF08801.11 KLO19298.1 - 0.034 12.9 0.0 0.13 11.0 0.0 1.9 2 1 0 2 2 2 0 Nup133 N terminal like RIO1 PF01163.22 KLO19298.1 - 0.047 13.3 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 KLO19299.1 - 6.8e-55 181.8 25.9 1.1e-08 35.6 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19299.1 - 6e-24 84.2 0.3 0.00025 21.3 0.0 6.5 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO19299.1 - 2.6e-12 46.3 0.7 0.1 11.5 0.0 6.1 1 1 5 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KLO19299.1 - 1.8e-08 34.1 0.0 0.3 10.4 0.0 4.7 5 0 0 5 5 5 3 WD40-like domain PD40 PF07676.12 KLO19299.1 - 6e-08 32.4 0.1 4.6 7.3 0.0 6.1 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KLO19299.1 - 4.5e-06 25.4 0.4 0.001 17.7 0.0 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 KLO19299.1 - 7.2e-06 24.9 0.4 0.57 8.8 0.0 4.4 2 2 2 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KLO19299.1 - 0.00031 20.2 0.9 8.5 5.6 0.0 4.5 1 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Peptidase_S9_N PF02897.15 KLO19299.1 - 0.00035 19.5 0.1 0.23 10.2 0.1 2.7 1 1 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF5122 PF17164.4 KLO19299.1 - 0.032 14.5 3.4 85 3.6 0.0 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF5122) beta-propeller Frtz PF11768.8 KLO19299.1 - 0.032 12.5 0.0 1.2 7.3 0.0 2.8 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Reg_prop PF07494.11 KLO19299.1 - 0.034 14.4 0.4 10 6.8 0.0 4.3 4 0 0 4 4 3 0 Two component regulator propeller VID27 PF08553.10 KLO19299.1 - 0.066 12.3 0.0 12 4.9 0.0 3.0 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain Proteasome_A_N PF10584.9 KLO19299.1 - 0.22 11.2 2.6 30 4.4 0.0 4.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Chalcone PF02431.15 KLO19301.1 - 0.04 13.3 0.0 0.077 12.4 0.0 1.4 2 0 0 2 2 2 0 Chalcone-flavanone isomerase MASE5 PF17178.4 KLO19302.1 - 0.0091 15.8 1.0 0.021 14.6 0.2 1.8 2 0 0 2 2 2 1 Membrane-associated sensor KleE PF17394.2 KLO19302.1 - 0.18 12.1 1.2 19 5.5 0.4 2.5 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein NUDIX PF00293.28 KLO19303.1 - 2.9e-15 56.5 1.4 7e-14 52.0 0.0 2.6 1 1 2 3 3 3 2 NUDIX domain Pox_A_type_inc PF04508.12 KLO19304.1 - 5.3e-05 22.9 5.1 0.17 11.8 0.1 3.8 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat LPP PF04728.13 KLO19304.1 - 0.035 14.5 2.3 0.035 14.5 2.3 3.9 4 1 0 4 4 4 0 Lipoprotein leucine-zipper PG_binding_1 PF01471.18 KLO19304.1 - 0.086 13.1 0.1 0.72 10.1 0.0 2.4 2 0 0 2 2 2 0 Putative peptidoglycan binding domain TSC22 PF01166.18 KLO19304.1 - 0.17 12.2 0.3 0.17 12.2 0.3 6.5 4 3 3 7 7 7 0 TSC-22/dip/bun family Syntaxin_2 PF14523.6 KLO19304.1 - 1.2 9.5 18.3 1.9 8.9 3.4 3.4 3 0 0 3 3 3 0 Syntaxin-like protein KASH_CCD PF14662.6 KLO19304.1 - 1.8 8.4 30.8 0.048 13.5 2.1 3.7 2 2 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH DUF3782 PF12644.7 KLO19304.1 - 2.6 8.3 12.3 6.8 6.9 0.2 3.6 2 2 0 4 4 4 0 Protein of unknown function (DUF3782) FlaC_arch PF05377.11 KLO19304.1 - 3.1 8.2 13.6 3.5 8.1 0.7 4.6 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 KLO19304.1 - 4 7.6 19.0 5.7 7.1 4.3 4.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 KLO19304.1 - 5.2 7.4 23.6 1.9 8.8 3.4 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 KLO19304.1 - 8.4 6.4 9.5 10 6.2 0.7 3.1 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RmlD_sub_bind PF04321.17 KLO19305.1 - 9.5e-56 189.0 0.0 1.2e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KLO19305.1 - 1.7e-25 89.9 0.0 3.3e-25 88.9 0.0 1.4 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO19305.1 - 1.6e-09 37.7 0.0 9.1e-09 35.1 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KLO19305.1 - 5.5e-06 25.7 0.0 0.00023 20.4 0.0 2.8 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KLO19305.1 - 0.00074 18.8 0.0 0.015 14.5 0.0 2.7 1 1 0 2 2 2 1 Male sterility protein NmrA PF05368.13 KLO19305.1 - 0.0028 17.2 0.1 0.017 14.7 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family DapB_N PF01113.20 KLO19305.1 - 0.016 15.3 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KLO19305.1 - 0.095 12.1 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF155 PF02582.14 KLO19308.1 - 7.2e-48 163.0 0.0 1.2e-47 162.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LSM PF01423.22 KLO19309.1 - 2e-16 59.5 0.1 2.5e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain CT_A_B PF02626.15 KLO19311.1 - 3.3e-68 230.2 0.0 5.8e-68 229.4 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KLO19311.1 - 3e-58 196.8 0.0 6.2e-58 195.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 KLO19311.1 - 1.6e-34 119.4 0.0 3.8e-34 118.2 0.0 1.6 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 KLO19311.1 - 3.7e-34 117.6 0.0 8.4e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KLO19311.1 - 1.1e-26 93.0 0.0 3.7e-26 91.3 0.0 1.9 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KLO19311.1 - 3e-08 33.4 0.0 6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 KLO19311.1 - 1.9e-07 30.8 2.8 6e-07 29.2 2.8 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme RimK PF08443.11 KLO19311.1 - 0.067 12.8 0.0 0.78 9.3 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATP-grasp PF02222.22 KLO19311.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.19 KLO19311.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DASH_Dam1 PF08653.10 KLO19312.1 - 2.5e-20 72.0 0.8 3.7e-20 71.5 0.2 1.6 2 0 0 2 2 2 1 DASH complex subunit Dam1 Aldo_ket_red PF00248.21 KLO19313.1 - 1.6e-77 260.6 0.0 1.9e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ELYS PF13934.6 KLO19314.1 - 1.8e-43 149.1 0.3 2.5e-43 148.6 0.3 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly Pkinase PF00069.25 KLO19316.1 - 7e-36 123.9 0.0 8.5e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19316.1 - 1.1e-19 70.8 0.0 1.4e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KLO19316.1 - 0.0022 17.4 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KLO19316.1 - 0.039 13.6 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KLO19316.1 - 0.079 12.9 0.2 0.18 11.7 0.2 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO19316.1 - 0.082 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4900 PF16241.5 KLO19318.1 - 0.13 12.6 0.2 0.24 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4900) NDUFA12 PF05071.16 KLO19319.1 - 0.00031 21.5 2.2 0.00069 20.4 2.2 1.8 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Cnl2_NKP2 PF09447.10 KLO19319.1 - 0.087 13.0 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Cnl2/NKP2 family protein GH-E PF14410.6 KLO19319.1 - 0.1 13.0 0.6 2.4 8.6 0.0 2.7 3 0 0 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues PPR PF01535.20 KLO19320.1 - 3.1e-06 27.1 0.0 0.0016 18.5 0.0 2.9 2 0 0 2 2 2 2 PPR repeat PPR_2 PF13041.6 KLO19320.1 - 0.004 17.3 0.0 0.0098 16.1 0.0 1.7 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.6 KLO19320.1 - 0.1 12.7 0.1 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Pentatricopeptide repeat domain SWIRM PF04433.17 KLO19321.1 - 6.6e-32 109.7 0.0 1.6e-31 108.5 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KLO19321.1 - 3.9e-22 78.0 12.1 7.4e-22 77.1 12.1 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KLO19321.1 - 6.4e-11 42.3 0.0 1.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KLO19321.1 - 3.4e-08 33.2 2.6 5.8e-08 32.4 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 KLO19321.1 - 1.9e-07 31.3 0.1 3.7e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KLO19321.1 - 0.089 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 REC1 PF18501.1 KLO19321.1 - 0.15 11.9 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Alpha helical recognition lobe domain Atg14 PF10186.9 KLO19321.1 - 0.82 8.7 3.6 1.5 7.9 3.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MFS_1 PF07690.16 KLO19322.1 - 7.8e-28 97.4 26.4 8.2e-28 97.3 25.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Hva1_TUDOR PF11160.8 KLO19323.1 - 3.3e-16 59.2 0.9 3.3e-16 59.2 0.9 2.7 3 0 0 3 3 3 1 Hypervirulence associated proteins TUDOR domain SPA PF08616.10 KLO19324.1 - 2e-33 114.8 0.0 3.7e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 KLO19324.1 - 4.6e-21 75.7 0.1 1.4e-16 61.1 0.0 2.6 2 0 0 2 2 2 2 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 KLO19324.1 - 0.00011 21.1 0.0 0.012 14.3 0.0 3.0 2 1 1 3 3 3 1 Transport protein Avl9 Peptidase_C14 PF00656.22 KLO19325.1 - 5.1e-34 118.3 0.0 7.2e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain RNA_pol_A_CTD PF03118.15 KLO19325.1 - 0.0044 16.7 0.1 0.0084 15.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain Peptidase_C14 PF00656.22 KLO19326.1 - 5.7e-25 88.7 0.1 7.4e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Caspase domain Helicase_C PF00271.31 KLO19328.1 - 9e-16 58.2 0.0 8.1e-15 55.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KLO19328.1 - 3.1e-11 43.3 0.0 1.2e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KLO19328.1 - 2e-06 27.9 0.0 2.4e-05 24.4 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 KLO19328.1 - 0.013 16.2 0.3 0.013 16.2 0.3 2.1 2 0 0 2 2 2 0 RecQ zinc-binding Rrn6 PF10214.9 KLO19328.1 - 0.074 11.6 3.1 0.11 11.0 3.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor eIF3_N PF09440.10 KLO19328.1 - 0.77 10.2 4.7 2.5 8.6 4.7 1.8 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain SecA_DEAD PF07517.14 KLO19328.1 - 0.85 8.9 0.0 0.85 8.9 0.0 2.4 2 1 0 2 2 2 0 SecA DEAD-like domain 5_nucleotid PF05761.14 KLO19328.1 - 8.8 5.1 7.1 15 4.4 7.1 1.3 1 0 0 1 1 1 0 5' nucleotidase family RIO1 PF01163.22 KLO19329.1 - 0.00013 21.7 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KLO19329.1 - 0.00044 19.7 0.1 0.0015 17.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 KLO19329.1 - 0.00068 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.25 KLO19329.1 - 0.00093 18.6 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KLO19329.1 - 0.0061 16.5 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family F-box-like PF12937.7 KLO19330.1 - 7.2e-08 32.2 5.3 1.1e-07 31.6 1.7 2.3 2 0 0 2 2 2 1 F-box-like T2SSJ PF11612.8 KLO19330.1 - 0.057 13.6 0.4 0.099 12.9 0.4 1.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein J MAPEG PF01124.18 KLO19331.1 - 2.7e-16 59.6 0.5 3.1e-16 59.4 0.5 1.1 1 0 0 1 1 1 1 MAPEG family Cnd3 PF12719.7 KLO19332.1 - 1.3e-80 270.8 7.7 2.3e-80 269.9 5.3 2.4 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KLO19332.1 - 0.00038 20.5 3.5 1.8 9.1 0.1 5.6 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 KLO19332.1 - 0.0068 16.8 4.2 0.62 10.5 1.1 4.3 3 1 2 5 5 5 2 HEAT repeats FMN_red PF03358.15 KLO19332.1 - 0.059 13.1 0.1 2.5 7.8 0.0 2.8 2 0 0 2 2 2 0 NADPH-dependent FMN reductase HEAT_EZ PF13513.6 KLO19332.1 - 0.081 13.5 1.6 17 6.1 0.0 4.0 3 1 0 3 3 3 0 HEAT-like repeat Cnd3 PF12719.7 KLO19333.1 - 4.1e-88 295.4 10.1 2.1e-86 289.8 4.0 2.8 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KLO19333.1 - 6.3e-12 44.7 5.2 0.026 14.8 0.1 6.1 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 KLO19333.1 - 1.3e-09 38.4 5.6 9.1e-06 26.0 1.3 4.3 3 1 0 3 3 3 2 HEAT repeats Adaptin_N PF01602.20 KLO19333.1 - 3.6e-06 25.8 1.2 2.8e-05 22.9 0.2 2.6 3 0 0 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.7 KLO19333.1 - 0.002 18.2 14.5 0.019 15.0 1.8 5.2 4 2 1 6 6 5 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KLO19333.1 - 0.0056 17.3 5.0 0.85 10.3 0.1 5.0 5 1 1 6 6 4 1 Vacuolar 14 Fab1-binding region SIL1 PF16782.5 KLO19333.1 - 0.011 15.0 4.4 0.026 13.7 0.4 2.6 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 APC_rep PF18797.1 KLO19333.1 - 0.025 15.5 0.9 0.098 13.6 0.9 2.1 1 0 0 1 1 1 0 Adenomatous polyposis coli (APC) repeat HEAT_EZ PF13513.6 KLO19333.1 - 0.026 15.0 3.1 5.9 7.5 0.0 4.8 3 1 2 5 5 5 0 HEAT-like repeat DUF2368 PF10166.9 KLO19333.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Muted PF14942.6 KLO19333.1 - 0.18 12.1 3.5 0.23 11.8 1.1 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Cohesin_HEAT PF12765.7 KLO19333.1 - 0.49 10.8 11.6 0.46 10.8 0.4 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion SPT6_acidic PF14632.6 KLO19333.1 - 0.65 10.6 9.3 0.15 12.7 4.5 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 DED PF01335.21 KLO19333.1 - 7.6 6.9 9.9 0.77 10.1 1.2 3.2 2 1 0 2 2 2 0 Death effector domain Pkinase PF00069.25 KLO19334.1 - 7.3e-73 245.2 0.0 1e-72 244.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19334.1 - 5.1e-45 153.8 0.0 7.8e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KLO19334.1 - 8.3e-39 131.6 0.3 6.7e-19 67.9 0.0 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KLO19334.1 - 1.1e-09 38.0 0.0 1.7e-08 34.2 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KLO19334.1 - 0.033 13.6 0.2 0.085 12.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KLO19334.1 - 0.048 12.6 0.1 0.1 11.5 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KLO19334.1 - 0.41 10.5 2.9 0.77 9.6 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-RING_2 PF13639.6 KLO19335.1 - 3.5e-10 40.1 13.0 6.9e-10 39.1 13.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KLO19335.1 - 8.6e-08 31.9 12.5 1.6e-07 31.0 12.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KLO19335.1 - 2.9e-06 26.9 8.8 5.6e-06 26.0 8.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KLO19335.1 - 8.3e-06 25.6 11.4 1.6e-05 24.7 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KLO19335.1 - 1.4e-05 25.3 13.3 7.7e-05 22.9 13.3 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KLO19335.1 - 4.3e-05 23.4 10.8 7.4e-05 22.6 10.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KLO19335.1 - 0.00013 21.8 9.8 0.00022 21.0 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KLO19335.1 - 0.0011 18.9 8.1 0.0029 17.6 8.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KLO19335.1 - 0.029 14.2 10.4 0.054 13.4 10.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KLO19335.1 - 0.035 13.7 10.3 0.077 12.6 10.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KLO19335.1 - 0.24 11.4 7.5 0.65 10.1 7.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Arf PF00025.21 KLO19336.1 - 2.7e-43 147.4 0.0 3.4e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KLO19336.1 - 1.6e-18 66.8 0.0 2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO19336.1 - 3.4e-14 53.1 0.0 5e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KLO19336.1 - 1.9e-08 34.0 0.0 2.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KLO19336.1 - 2e-07 30.6 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KLO19336.1 - 7e-06 25.4 1.9 8.7e-05 21.8 0.3 2.7 1 1 2 3 3 3 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KLO19336.1 - 3.7e-05 23.8 0.0 5.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KLO19336.1 - 0.012 15.1 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KLO19336.1 - 0.018 15.1 0.4 0.74 9.8 0.7 2.2 1 1 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 KLO19336.1 - 0.1 12.4 0.1 7.5 6.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CBS PF00571.28 KLO19339.1 - 4.3e-08 33.5 0.1 2.5 8.6 0.0 4.7 4 0 0 4 4 4 4 CBS domain Vps39_2 PF10367.9 KLO19340.1 - 1.1e-09 38.8 0.0 2.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KLO19340.1 - 7.7e-07 29.4 0.1 5.6e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 KLO19340.1 - 1.8e-06 27.8 0.0 2e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KLO19340.1 - 0.002 18.0 0.0 0.077 12.9 0.0 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_16 PF13432.6 KLO19340.1 - 0.32 11.7 1.5 1.2 9.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Perilipin PF03036.16 KLO19341.1 - 6.5e-08 32.0 10.9 2.8e-06 26.6 0.1 2.8 2 1 0 2 2 2 2 Perilipin family Apolipoprotein PF01442.18 KLO19341.1 - 0.018 14.9 4.5 0.038 13.9 3.7 1.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KLO19341.1 - 0.17 11.9 3.7 5.2 7.1 1.8 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.32 KLO19343.1 - 6.3e-17 61.7 4.2 0.0001 23.0 0.0 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19343.1 - 1.3e-11 44.6 0.0 0.0073 16.6 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KLO19343.1 - 0.0032 17.9 0.1 28 5.4 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain eIF2A PF08662.11 KLO19343.1 - 0.028 14.3 0.1 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KLO19343.1 - 0.038 12.9 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_3 PF15911.5 KLO19343.1 - 0.091 12.8 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat CNH PF00780.22 KLO19343.1 - 0.21 11.1 0.0 1.4 8.4 0.0 2.0 1 1 0 1 1 1 0 CNH domain Cnd1 PF12717.7 KLO19344.1 - 5.7e-58 195.5 2.9 4.7e-52 176.3 0.8 3.2 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 KLO19344.1 - 1.5e-54 184.3 0.0 1.5e-54 184.3 0.0 4.3 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 KLO19344.1 - 5e-07 30.0 0.0 0.28 11.6 0.0 4.8 4 1 1 5 5 5 3 HEAT repeats ENTH PF01417.20 KLO19344.1 - 4.3e-05 23.5 6.0 0.15 12.1 0.1 4.5 4 0 0 4 4 4 2 ENTH domain RTP1_C1 PF10363.9 KLO19344.1 - 6.2e-05 23.2 2.8 0.82 9.9 0.1 4.1 2 1 1 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KLO19344.1 - 0.00021 21.2 0.5 21 5.7 0.0 5.6 5 0 0 5 5 5 0 HEAT repeat Adaptin_N PF01602.20 KLO19344.1 - 0.0033 16.0 14.0 0.13 10.8 0.7 4.1 3 2 1 4 4 4 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 KLO19344.1 - 0.02 14.2 2.6 0.64 9.3 0.3 2.8 3 0 0 3 3 3 0 V-ATPase subunit H DUF1186 PF06685.11 KLO19344.1 - 0.034 13.5 1.8 0.056 12.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1186) HEAT_EZ PF13513.6 KLO19344.1 - 0.091 13.3 0.6 2.4e+02 2.4 0.0 5.4 6 0 0 6 6 6 0 HEAT-like repeat YtzH PF14165.6 KLO19344.1 - 0.18 12.2 1.4 0.88 10.0 0.2 2.8 2 1 1 3 3 3 0 YtzH-like protein PIP5K PF01504.18 KLO19345.1 - 1.8e-93 312.8 0.0 3.3e-93 311.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_S26 PF10502.9 KLO19345.1 - 0.15 11.8 0.0 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 Glyco_transf_24 PF18404.1 KLO19346.1 - 3.5e-143 475.9 3.1 5.1e-143 475.3 3.1 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KLO19346.1 - 5.2e-65 219.9 0.1 3.2e-64 217.3 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KLO19346.1 - 3.2e-49 167.4 0.1 6e-49 166.5 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KLO19346.1 - 2.8e-41 140.0 0.0 5.6e-41 139.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KLO19346.1 - 2.3e-38 131.2 5.1 5.2e-38 130.0 1.9 3.0 3 1 1 4 4 4 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KLO19346.1 - 3.3e-36 125.2 0.7 3.6e-33 115.3 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KLO19346.1 - 2.2e-05 24.1 0.1 4.2e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 E1-E2_ATPase PF00122.20 KLO19347.1 - 1.1e-46 158.6 0.0 1.1e-46 158.6 0.0 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KLO19347.1 - 1.4e-16 61.5 5.0 7.8e-16 59.0 5.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KLO19347.1 - 4.8e-13 48.6 0.0 1.1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KLO19347.1 - 5.1e-05 23.1 0.0 0.00052 19.8 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KLO19347.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Endotoxin_N PF03945.14 KLO19347.1 - 0.035 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain DUF2666 PF10869.8 KLO19347.1 - 0.073 13.3 0.3 0.23 11.7 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) GIDA_assoc PF13932.6 KLO19349.1 - 0.021 15.0 0.1 0.026 14.7 0.1 1.1 1 0 0 1 1 1 0 GidA associated domain Pkinase PF00069.25 KLO19350.1 - 1.9e-05 24.2 0.0 4.3e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19350.1 - 0.033 13.5 0.0 0.064 12.5 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Peptidase_C50 PF03568.17 KLO19352.1 - 3.6e-137 457.7 0.0 1.1e-136 456.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.6 KLO19352.1 - 3.4e-07 30.5 7.6 0.31 11.3 0.0 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO19352.1 - 0.0011 18.4 0.1 0.0011 18.4 0.1 3.5 4 0 0 4 4 4 1 MalT-like TPR region TPR_16 PF13432.6 KLO19352.1 - 0.0018 18.9 11.1 0.019 15.6 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KLO19352.1 - 0.0022 18.0 17.1 13 6.2 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat CHAT PF12770.7 KLO19352.1 - 0.0055 16.2 0.0 0.069 12.6 0.0 2.4 1 1 0 1 1 1 1 CHAT domain TPR_11 PF13414.6 KLO19352.1 - 0.015 14.9 4.6 0.43 10.3 0.1 4.6 5 0 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 KLO19352.1 - 0.075 13.3 11.0 14 6.2 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 KLO19352.1 - 0.13 12.2 10.4 14 5.7 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KLO19352.1 - 0.36 11.8 5.2 10 7.2 0.1 5.7 7 1 1 8 8 8 0 Tetratricopeptide repeat adh_short PF00106.25 KLO19353.1 - 5.8e-26 91.2 0.0 7.5e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO19353.1 - 4.8e-20 72.1 0.0 5.7e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KLO19353.1 - 3.2e-05 23.9 0.0 4.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KLO19353.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO19353.1 - 0.01 15.3 0.0 0.048 13.1 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Op_neuropeptide PF08035.11 KLO19353.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Opioids neuropeptide HECT_2 PF09814.9 KLO19354.1 - 9e-44 149.8 0.0 1.8e-43 148.9 0.0 1.5 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding P120R PF08062.11 KLO19354.1 - 0.17 12.3 1.5 0.5 10.8 1.5 1.8 1 0 0 1 1 1 0 P120R (NUC006) repeat DUF932 PF06067.11 KLO19354.1 - 0.21 11.3 0.7 0.42 10.3 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF932) UBM PF14377.6 KLO19354.1 - 9.8 5.8 10.8 5 6.7 0.4 4.3 4 1 0 4 4 4 0 Ubiquitin binding region GRAB PF10375.9 KLO19355.1 - 2.5e-07 30.3 1.9 5.8e-07 29.2 1.9 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GRIP PF01465.20 KLO19355.1 - 0.0032 17.4 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 GRIP domain BRE1 PF08647.11 KLO19355.1 - 0.018 15.1 4.5 0.018 15.1 4.5 3.8 1 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase GIT_CC PF16559.5 KLO19355.1 - 0.029 14.2 3.2 0.029 14.2 3.2 3.4 4 1 1 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor ANTAR PF03861.14 KLO19355.1 - 0.059 13.2 5.5 2.2 8.2 0.1 3.7 3 0 0 3 3 3 0 ANTAR domain LPP PF04728.13 KLO19355.1 - 0.4 11.1 5.9 0.29 11.5 3.0 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 KLO19355.1 - 5.5 7.0 43.0 0.031 14.3 25.2 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MCD_N PF17408.2 KLO19355.1 - 5.9 7.1 10.6 0.47 10.6 3.6 2.6 2 1 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain DUF667 PF05018.13 KLO19356.1 - 3e-29 102.1 0.1 5.1e-16 58.9 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF667) WD40 PF00400.32 KLO19357.1 - 3.1e-11 43.6 4.9 0.00079 20.2 0.1 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19357.1 - 7.3e-07 29.4 0.2 0.24 11.7 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KLO19357.1 - 0.024 14.4 0.1 0.25 11.1 0.1 2.2 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Endotoxin_N PF03945.14 KLO19357.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Orthopox_F14 PF06076.12 KLO19357.1 - 0.13 12.5 1.8 0.22 11.8 0.5 2.0 2 0 0 2 2 2 0 Orthopoxvirus F14 protein FlgN PF05130.12 KLO19357.1 - 0.39 11.2 2.2 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 FlgN protein Amidase PF01425.21 KLO19358.1 - 3.4e-104 349.3 0.0 4e-104 349.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 KLO19359.1 - 6.4e-103 345.1 0.0 7.7e-103 344.8 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF3439 PF11921.8 KLO19359.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) WD40 PF00400.32 KLO19360.1 - 9.3e-11 42.1 1.2 0.0003 21.5 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19360.1 - 2.2e-05 24.7 0.0 2 8.7 0.0 4.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KLO19360.1 - 0.012 15.5 0.1 19 5.0 0.0 4.0 2 2 3 5 5 5 0 Eukaryotic translation initiation factor eIF2A Dor1 PF04124.12 KLO19360.1 - 0.05 12.3 0.2 0.21 10.2 0.0 1.9 2 0 0 2 2 2 0 Dor1-like family Iso_dh PF00180.20 KLO19361.1 - 2e-83 280.4 0.0 2.4e-83 280.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WD40 PF00400.32 KLO19364.1 - 5.7e-10 39.6 5.7 1.9e-05 25.3 0.0 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19364.1 - 5.2e-05 23.5 0.1 0.2 12.0 0.0 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KLO19364.1 - 0.063 11.3 0.1 2.4 6.1 0.0 2.6 3 0 0 3 3 3 0 IKI3 family Ge1_WD40 PF16529.5 KLO19364.1 - 0.099 11.6 0.0 0.22 10.4 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ABC_tran PF00005.27 KLO19365.1 - 2.8e-49 167.2 0.0 1.6e-29 103.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KLO19365.1 - 1.2e-42 146.5 30.8 1.1e-23 84.3 10.7 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KLO19365.1 - 6.3e-09 35.6 0.0 0.0014 18.1 1.0 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KLO19365.1 - 0.00039 20.0 0.1 0.13 11.8 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KLO19365.1 - 0.00076 19.8 0.6 3.2 8.0 0.2 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KLO19365.1 - 0.0026 17.5 1.1 0.42 10.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KLO19365.1 - 0.0054 16.5 0.2 0.039 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO19365.1 - 0.0066 16.8 0.1 0.47 10.8 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KLO19365.1 - 0.016 15.3 0.1 0.042 14.0 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain ATPase PF06745.13 KLO19365.1 - 0.024 14.0 0.0 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.6 KLO19365.1 - 0.033 14.7 0.2 11 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KLO19365.1 - 0.035 13.1 0.0 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 KLO19365.1 - 0.13 12.0 0.0 26 4.5 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein Pox_A32 PF04665.12 KLO19365.1 - 0.17 11.4 1.2 8.3 5.8 0.2 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein NB-ARC PF00931.22 KLO19365.1 - 0.46 9.6 1.9 2.5 7.2 0.2 2.9 3 1 0 3 3 3 0 NB-ARC domain cobW PF02492.19 KLO19365.1 - 0.7 9.5 2.4 1.2 8.7 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KLO19366.1 - 9.5e-46 155.7 0.0 4.5e-27 95.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KLO19366.1 - 1.3e-43 149.6 21.8 3.8e-27 95.7 3.6 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KLO19366.1 - 4.7e-09 36.0 0.1 0.0024 17.3 0.0 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KLO19366.1 - 0.00015 20.9 0.1 0.43 9.6 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 KLO19366.1 - 0.00023 20.8 0.1 0.079 12.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KLO19366.1 - 0.0014 18.7 2.1 0.064 13.3 0.1 2.8 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_22 PF13401.6 KLO19366.1 - 0.0058 16.9 3.0 2.1 8.7 0.2 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KLO19366.1 - 0.0065 16.2 1.2 2.2 8.1 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KLO19366.1 - 0.034 13.5 0.0 6.4 6.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KLO19366.1 - 0.039 14.3 0.4 3.1 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.9 KLO19366.1 - 0.075 12.3 0.3 0.94 8.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KLO19366.1 - 0.08 12.3 0.5 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.6 KLO19366.1 - 0.12 12.8 0.4 11 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KLO19366.1 - 0.14 11.6 2.0 1.6 8.1 0.3 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein NB-ARC PF00931.22 KLO19366.1 - 0.16 11.1 0.2 5.8 6.0 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain DEAD PF00270.29 KLO19366.1 - 0.21 11.3 0.3 8.6 6.1 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase NACHT PF05729.12 KLO19366.1 - 0.23 11.4 1.3 12 5.8 0.2 2.4 2 0 0 2 2 2 0 NACHT domain Methyltransf_16 PF10294.9 KLO19367.1 - 8.3e-10 38.7 0.0 1.7e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase PDEase_I PF00233.19 KLO19373.1 - 7.5e-60 202.6 0.2 1.3e-59 201.8 0.2 1.4 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TENA_THI-4 PF03070.16 KLO19374.1 - 9.5e-13 48.4 0.1 4.7e-12 46.2 0.1 1.8 1 1 0 1 1 1 1 TENA/THI-4/PQQC family HCO3_cotransp PF00955.21 KLO19375.1 - 9.2e-68 229.3 7.1 2.5e-36 125.6 3.9 3.0 2 1 1 3 3 3 3 HCO3- transporter family Sulfate_transp PF00916.20 KLO19375.1 - 0.0005 18.9 1.5 0.0005 18.9 1.5 1.6 1 1 0 1 1 1 1 Sulfate permease family MutS_V PF00488.21 KLO19376.1 - 1.3e-65 221.0 0.1 2.6e-65 220.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KLO19376.1 - 2.6e-38 132.2 0.8 5.9e-38 131.0 0.2 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KLO19376.1 - 8.1e-32 109.8 0.1 1.7e-31 108.8 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KLO19376.1 - 1.1e-10 41.9 0.0 4e-10 40.1 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KLO19376.1 - 0.00044 20.5 0.0 0.0014 19.0 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV DUF2203 PF09969.9 KLO19376.1 - 0.16 12.7 0.1 25 5.6 0.0 3.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Formyl_trans_N PF00551.19 KLO19377.1 - 5.5e-23 81.6 0.0 9.7e-23 80.8 0.0 1.4 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KLO19377.1 - 4.5e-08 33.2 0.0 8.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Asp PF00026.23 KLO19378.1 - 1.2e-33 116.9 5.3 7.9e-25 87.9 5.2 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KLO19378.1 - 3.2e-09 37.3 2.5 7.8e-08 32.8 2.5 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KLO19378.1 - 0.0088 16.7 0.2 1.9 9.2 0.0 3.0 2 1 0 2 2 2 1 Aspartyl protease ERM PF00769.19 KLO19379.1 - 0.034 14.0 18.9 0.062 13.1 18.9 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3584 PF12128.8 KLO19379.1 - 0.083 10.4 17.1 0.14 9.6 17.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Leu_zip PF15294.6 KLO19379.1 - 0.8 9.2 7.5 0.85 9.1 6.5 1.4 1 1 0 1 1 1 0 Leucine zipper HIP1_clath_bdg PF16515.5 KLO19379.1 - 2.8 8.6 13.4 2.8 8.6 4.2 3.4 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF148 PF02520.17 KLO19379.1 - 3.8 7.7 9.5 1.7 8.8 2.9 2.6 1 1 1 2 2 2 0 Domain of unknown function DUF148 Fib_alpha PF08702.10 KLO19379.1 - 6.3 7.0 4.6 18 5.5 1.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DNA_primase_S PF01896.19 KLO19383.1 - 1e-54 185.3 0.1 1.4e-54 184.9 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit Rad51 PF08423.11 KLO19384.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Rad51 HHH_5 PF14520.6 KLO19384.1 - 0.15 12.7 0.0 0.46 11.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain ATPase PF06745.13 KLO19384.1 - 0.21 10.9 0.1 12 5.1 0.3 2.1 1 1 1 2 2 2 0 KaiC 5-FTHF_cyc-lig PF01812.20 KLO19385.1 - 8.6e-40 136.6 0.0 1.1e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LtuA PF17446.2 KLO19386.1 - 0.061 13.7 0.9 0.1 13.0 0.9 1.4 1 0 0 1 1 1 0 Late transcription unit A YSIRK_signal PF04650.17 KLO19386.1 - 0.17 11.7 1.3 0.41 10.6 1.3 1.7 1 0 0 1 1 1 0 YSIRK type signal peptide Tagatose_6_P_K PF08013.11 KLO19389.1 - 0.087 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase zf-C2H2 PF00096.26 KLO19390.1 - 2.1e-09 37.3 6.4 0.00022 21.5 0.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KLO19390.1 - 2.4e-07 30.9 6.7 0.0001 22.6 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KLO19390.1 - 2.6e-07 30.9 5.1 0.002 18.8 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KLO19390.1 - 5.7e-06 26.5 0.9 0.0056 17.0 0.0 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KLO19390.1 - 2.6e-05 24.4 0.2 0.017 15.4 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KLO19390.1 - 0.0036 17.3 1.3 0.014 15.4 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 KLO19390.1 - 4.3 7.9 6.4 1.2 9.6 0.8 3.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain PIG-P PF08510.12 KLO19391.1 - 3.2e-35 120.7 6.0 3.9e-35 120.4 6.0 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KLO19391.1 - 3.6 8.0 12.5 23 5.4 12.4 2.2 1 1 1 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Nrap_D3 PF17404.2 KLO19392.1 - 0.16 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Nrap protein domain 3 YibE_F PF07907.11 KLO19393.1 - 0.0094 15.5 0.4 0.0094 15.5 0.4 1.8 2 0 0 2 2 2 1 YibE/F-like protein DUF4231 PF14015.6 KLO19393.1 - 2.6 8.5 8.9 7.6 7.1 2.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) DUF4064 PF13273.6 KLO19393.1 - 4 7.8 8.1 22 5.4 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Nop14 PF04147.12 KLO19394.1 - 0.038 12.2 0.2 0.049 11.9 0.2 1.1 1 0 0 1 1 1 0 Nop14-like family ICMT PF04140.14 KLO19395.1 - 3.8e-10 40.0 1.1 1e-09 38.7 0.2 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KLO19395.1 - 4.5e-08 32.3 0.0 9.3e-08 31.2 0.0 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 KLO19395.1 - 5.9e-07 29.8 4.8 4.7e-06 26.9 0.6 2.9 3 0 0 3 3 3 1 Phospholipid methyltransferase HAD_2 PF13419.6 KLO19396.1 - 6.5e-14 52.4 0.0 1.6e-13 51.1 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KLO19396.1 - 1.5e-07 31.9 0.0 2.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO19396.1 - 0.00042 20.3 0.0 0.00098 19.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KLO19396.1 - 0.0011 19.4 0.0 0.0016 18.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase EXS PF03124.14 KLO19397.1 - 1.9e-62 211.5 17.0 2.2e-62 211.3 17.0 1.0 1 0 0 1 1 1 1 EXS family XTBD PF11952.8 KLO19397.1 - 0.096 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD Vps16_C PF04840.12 KLO19398.1 - 1.5e-85 287.1 0.1 1.9e-85 286.7 0.1 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 KLO19398.1 - 3e-82 276.6 0.0 4.9e-82 275.9 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region RIB43A PF05914.12 KLO19398.1 - 0.0019 17.0 1.4 0.003 16.4 1.4 1.1 1 0 0 1 1 1 1 RIB43A Arrestin_N PF00339.29 KLO19399.1 - 0.053 13.6 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain FANCI_S4 PF14678.6 KLO19401.1 - 0.0031 16.7 0.0 0.007 15.5 0.0 1.5 1 0 0 1 1 1 1 FANCI solenoid 4 Peptidase_C48 PF02902.19 KLO19401.1 - 0.033 14.0 0.5 0.081 12.8 0.4 1.7 1 1 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain DUF2076 PF09849.9 KLO19402.1 - 7.9e-06 26.1 13.9 1.1e-05 25.6 13.9 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KLO19402.1 - 1.3e-05 25.2 0.4 2e-05 24.6 0.4 1.3 1 0 0 1 1 1 1 CHCH domain CCDC53 PF10152.9 KLO19402.1 - 4 7.8 11.1 7.6 6.9 0.1 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TPR_12 PF13424.6 KLO19403.1 - 0.014 15.6 1.5 0.26 11.6 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KLO19403.1 - 0.043 13.9 0.2 0.14 12.2 0.2 1.9 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KLO19403.1 - 0.067 14.0 1.5 17 6.5 0.8 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KLO19403.1 - 0.087 12.9 0.6 21 5.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KLO19404.1 - 3.2e-05 24.1 1.6 0.051 13.9 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KLO19404.1 - 0.00061 19.7 1.6 1.7 8.9 0.4 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KLO19404.1 - 0.002 18.0 0.1 0.33 11.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO19404.1 - 0.065 12.6 2.1 0.63 9.4 0.0 2.7 2 1 0 2 2 2 0 MalT-like TPR region TPR_14 PF13428.6 KLO19404.1 - 0.091 13.6 3.9 1.5 9.9 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1206 PF06724.11 KLO19404.1 - 0.23 11.6 0.7 3 8.0 0.3 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) TPR_8 PF13181.6 KLO19404.1 - 0.26 11.6 1.6 43 4.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KLO19404.1 - 2.5 8.1 5.1 20 5.2 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KLO19404.1 - 2.5 8.1 9.1 0.71 9.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec62 PF03839.16 KLO19405.1 - 1.3e-53 181.7 6.2 1e-52 178.8 6.2 1.9 1 1 0 1 1 1 1 Translocation protein Sec62 DUF3413 PF11893.8 KLO19405.1 - 0.15 11.2 6.7 0.23 10.6 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) RNA_pol_N PF01194.17 KLO19406.1 - 9.2e-31 105.9 0.1 1.1e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit NMD3 PF04981.13 KLO19407.1 - 5.2e-81 271.7 0.8 7.4e-81 271.2 0.8 1.2 1 0 0 1 1 1 1 NMD3 family NinF PF05810.12 KLO19407.1 - 0.058 13.3 0.7 0.058 13.3 0.7 2.5 3 1 1 4 4 4 0 NinF protein DZR PF12773.7 KLO19407.1 - 0.34 11.0 7.4 14 5.8 7.4 2.6 1 1 0 1 1 1 0 Double zinc ribbon DUF4191 PF13829.6 KLO19408.1 - 2.1 7.6 3.3 9.1 5.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Malic_M PF03949.15 KLO19410.1 - 6.4e-94 314.0 0.0 8.1e-94 313.7 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KLO19410.1 - 3e-62 209.7 0.0 4.4e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Poxvirus_B22R_C PF13168.6 KLO19410.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal EphA2_TM PF14575.6 KLO19412.1 - 0.038 14.9 0.0 0.084 13.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gram_pos_anchor PF00746.21 KLO19412.1 - 0.19 11.7 0.5 0.44 10.5 0.5 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif CD34_antigen PF06365.12 KLO19412.1 - 0.2 11.2 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Amnionless PF14828.6 KLO19412.1 - 0.22 10.3 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless RabGAP-TBC PF00566.18 KLO19413.1 - 8.4e-19 68.1 0.0 1.2e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HbrB PF08539.11 KLO19414.1 - 1.7e-33 116.0 0.0 2e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 HbrB-like Sec7 PF01369.20 KLO19415.1 - 4.7e-27 94.9 0.0 6.9e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Erf4 PF10256.9 KLO19416.1 - 0.0024 18.0 0.0 0.0062 16.6 0.0 1.7 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Erf4 PF10256.9 KLO19417.1 - 0.004 17.3 0.0 0.0087 16.2 0.0 1.6 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3712 PF12505.8 KLO19419.1 - 2.1e-109 360.8 70.2 9.1e-26 90.6 3.1 9.4 11 0 0 11 11 11 6 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KLO19419.1 - 2.4e-09 37.6 13.8 0.14 12.7 0.0 9.5 9 0 0 9 9 9 4 Late embryogenesis abundant protein Acyltransferase PF01553.21 KLO19420.1 - 5.3e-12 45.5 0.0 8.3e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ctr PF04145.15 KLO19421.1 - 0.0035 18.0 0.4 0.01 16.5 0.0 1.9 1 1 1 2 2 2 1 Ctr copper transporter family DUF1129 PF06570.11 KLO19421.1 - 0.023 14.2 4.1 0.11 12.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) DUF4834 PF16118.5 KLO19421.1 - 1.1 10.2 0.0 1.1 10.2 0.0 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Phage_holin_3_6 PF07332.11 KLO19421.1 - 5.6 7.0 8.8 0.45 10.6 0.3 2.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1129 PF06570.11 KLO19422.1 - 0.013 15.0 1.2 0.97 8.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4834 PF16118.5 KLO19422.1 - 0.25 12.3 0.8 0.47 11.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF1218 PF06749.12 KLO19422.1 - 1.1 9.8 9.2 9.8 6.8 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) DUF4064 PF13273.6 KLO19424.1 - 0.36 11.1 4.8 3 8.1 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) NUC173 PF08161.12 KLO19425.1 - 1.6e-54 184.7 0.0 2.3e-51 174.4 0.0 3.4 4 0 0 4 4 4 2 NUC173 domain MMS19_C PF12460.8 KLO19425.1 - 0.0044 16.2 15.9 0.024 13.8 1.9 3.9 2 2 1 3 3 3 2 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 KLO19425.1 - 0.0052 17.1 0.6 0.48 10.9 0.0 3.7 3 0 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 KLO19425.1 - 0.037 14.1 0.1 0.73 9.9 0.0 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KLO19425.1 - 0.04 14.2 0.4 3.3 8.2 0.2 3.7 3 0 0 3 3 3 0 HEAT repeat Acyltransferase PF01553.21 KLO19426.1 - 1.2e-13 50.9 0.0 2.9e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 Acyltransferase NdhL PF10716.9 KLO19426.1 - 0.055 13.4 6.7 1.1 9.3 0.7 2.5 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit PKcGMP_CC PF16808.5 KLO19426.1 - 1 9.3 3.0 0.41 10.5 0.4 1.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Helicase_C PF00271.31 KLO19427.1 - 2.2e-23 82.7 0.0 6.8e-23 81.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KLO19427.1 - 1.3e-18 67.0 4.5 3.6e-18 65.6 4.5 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain DEAD PF00270.29 KLO19427.1 - 4.9e-16 59.0 0.3 1.9e-14 53.8 0.0 2.8 2 1 1 3 3 3 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KLO19427.1 - 0.017 14.3 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase IMS PF00817.20 KLO19428.1 - 8.6e-40 136.2 0.0 1.6e-39 135.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KLO19428.1 - 2.4e-12 47.6 0.0 6.3e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KLO19428.1 - 8.3e-08 32.1 0.0 2.1e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif UBZ_FAAP20 PF15750.5 KLO19428.1 - 0.034 14.1 0.2 0.099 12.6 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger Choline_transpo PF04515.12 KLO19429.1 - 1.8e-62 211.5 15.2 1.8e-62 211.5 15.2 2.2 2 1 0 2 2 2 1 Plasma-membrane choline transporter TMEMspv1-c74-12 PF11044.8 KLO19429.1 - 1.5 8.8 10.3 1.2 9.1 2.6 2.9 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Glyco_hydro_16 PF00722.21 KLO19430.1 - 2.6e-17 62.8 0.1 1.5e-16 60.4 0.1 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Ssl1 PF04056.14 KLO19431.1 - 7.9e-70 234.6 0.0 1.2e-69 234.0 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KLO19431.1 - 1e-14 54.5 12.8 1e-14 54.5 12.8 2.9 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.6 KLO19431.1 - 9e-14 52.0 0.0 1.8e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 KLO19431.1 - 0.0038 16.8 2.9 2.8 7.4 0.0 2.4 2 1 0 2 2 2 2 Transcription factor Tfb4 VWA PF00092.28 KLO19431.1 - 0.0045 17.3 0.0 0.0069 16.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.21 KLO19431.1 - 2.9 8.2 19.7 0.058 13.6 10.3 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_15 PF17032.5 KLO19431.1 - 7 7.5 16.8 0.19 12.5 8.4 2.5 2 1 0 2 2 2 0 zinc-ribbon family SAM_decarbox PF01536.16 KLO19432.1 - 4.8e-117 390.9 0.0 3e-116 388.3 0.0 1.9 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase PP2C PF00481.21 KLO19433.1 - 6.1e-20 71.9 0.0 3.5e-18 66.2 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KLO19433.1 - 5.9e-06 26.1 0.0 1.2e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C T6SS_TssG PF06996.11 KLO19433.1 - 0.1 11.8 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion, TssG zf-U1 PF06220.12 KLO19434.1 - 8.6e-10 38.2 1.0 1.5e-09 37.5 1.0 1.4 1 0 0 1 1 1 1 U1 zinc finger CTP_transf_1 PF01148.20 KLO19435.1 - 4.4e-74 249.6 18.9 6.1e-74 249.1 18.9 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosom_S12_S23 PF00164.25 KLO19436.1 - 2e-46 156.3 0.2 2.6e-46 155.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosom_S12_S23 PF00164.25 KLO19437.1 - 1.1e-47 160.4 0.4 1.4e-47 160.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Abhydrolase_1 PF00561.20 KLO19438.1 - 8.2e-21 74.8 0.5 1.5e-20 74.0 0.5 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO19438.1 - 1.1e-06 29.4 0.1 1.4e-06 29.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO19438.1 - 0.0031 16.8 0.0 0.0079 15.5 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KLO19438.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 KLO19439.1 - 1.2e-13 51.3 0.1 3.2e-13 49.9 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold EMP70 PF02990.16 KLO19440.1 - 1e-192 641.5 0.1 1.6e-192 640.9 0.1 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 TMEM40 PF15817.5 KLO19440.1 - 0.87 9.4 3.9 3.1 7.6 3.9 1.9 1 0 0 1 1 1 0 Transmembrane protein 40 family tRNA-synt_1b PF00579.25 KLO19441.1 - 1.5e-75 254.3 0.0 2.1e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KLO19441.1 - 0.041 13.7 0.0 0.14 12.0 0.0 1.8 1 1 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 KLO19441.1 - 0.045 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 S4 domain TGT PF01702.18 KLO19442.1 - 3.7e-131 437.4 0.0 4.9e-131 437.0 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Glyco_hydro_70 PF02324.16 KLO19442.1 - 0.13 10.4 0.0 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 RCC1 PF00415.18 KLO19443.1 - 3.2e-23 82.1 3.7 6.4e-10 39.5 0.1 7.5 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KLO19443.1 - 2.6e-09 36.7 10.9 0.0047 16.7 0.4 5.6 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.32 KLO19444.1 - 9.4e-102 330.1 46.3 3.4e-10 40.3 0.1 15.7 16 0 0 16 16 16 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19444.1 - 3e-40 136.4 0.0 0.00023 21.4 0.0 12.4 1 1 9 12 12 12 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO19444.1 - 2.7e-16 59.4 3.7 0.02 13.9 0.0 10.6 3 2 7 12 12 12 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KLO19444.1 - 3.6e-12 46.6 0.0 0.31 10.9 0.1 5.7 2 2 3 6 6 6 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KLO19444.1 - 7.1e-11 41.8 4.8 0.57 10.2 0.0 9.7 10 0 0 10 10 10 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KLO19444.1 - 6.2e-08 32.3 0.0 0.073 12.4 0.0 5.6 6 1 0 6 6 6 2 WD40-like domain Cytochrom_D1 PF02239.16 KLO19444.1 - 1.1e-05 24.1 0.2 0.39 9.2 0.0 3.6 4 0 0 4 4 4 2 Cytochrome D1 heme domain AAA_16 PF13191.6 KLO19444.1 - 4.5e-05 23.9 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Nbas_N PF15492.6 KLO19444.1 - 0.0017 17.8 11.7 4.2 6.6 0.0 8.3 7 2 4 12 12 12 1 Neuroblastoma-amplified sequence, N terminal nos_propeller PF18764.1 KLO19444.1 - 0.0035 17.2 1.9 6.2 6.8 0.0 5.3 5 1 1 6 6 6 1 Nitrous oxide reductase propeller repeat Nup160 PF11715.8 KLO19444.1 - 0.004 15.9 2.6 7 5.2 0.0 5.8 6 1 1 7 7 7 1 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 KLO19444.1 - 0.071 12.8 14.1 7.1 6.4 0.0 8.3 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature Mg_chelatase PF01078.21 KLO19444.1 - 0.088 12.2 0.4 0.18 11.2 0.4 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KLO19444.1 - 0.12 12.1 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KLO19444.1 - 0.14 12.6 0.0 0.65 10.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KLO19444.1 - 0.18 11.7 0.2 0.3 11.0 0.2 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.6 KLO19444.1 - 0.2 11.5 0.6 0.77 9.5 0.2 2.3 2 0 0 2 2 1 0 P-loop containing region of AAA domain NHL PF01436.21 KLO19444.1 - 0.44 10.7 1.3 41 4.5 0.2 4.2 3 0 0 3 3 3 0 NHL repeat DASH_Duo1 PF08651.10 KLO19445.1 - 6.4e-19 67.5 0.1 9.5e-19 66.9 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 MAP7 PF05672.11 KLO19445.1 - 0.014 15.1 24.9 0.014 15.1 24.9 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family DUF4637 PF15470.6 KLO19445.1 - 2.6 7.8 22.6 0.54 10.0 5.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) ATG27 PF09451.10 KLO19446.1 - 3.3e-65 220.6 0.0 4.4e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KLO19446.1 - 0.0047 16.1 0.0 0.008 15.3 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Josephin PF02099.17 KLO19447.1 - 2.6e-49 167.4 0.3 4.5e-49 166.7 0.3 1.3 1 0 0 1 1 1 1 Josephin UIM PF02809.20 KLO19447.1 - 0.00035 20.3 11.4 0.00058 19.6 3.7 5.1 5 0 0 5 5 5 2 Ubiquitin interaction motif 3-PAP PF12578.8 KLO19447.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Myotubularin-associated protein Pyrid_ox_like PF16242.5 KLO19448.1 - 3e-32 111.3 0.0 4.8e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KLO19448.1 - 7.3e-10 38.9 0.0 1.7e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase PP2C PF00481.21 KLO19449.1 - 1.9e-23 83.5 0.0 1.8e-19 70.4 0.0 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KLO19449.1 - 6.4e-07 29.2 0.2 1.6e-05 24.6 0.1 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 KLO19449.1 - 0.072 13.0 0.7 0.15 12.0 0.1 1.9 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) bPH_2 PF03703.14 KLO19451.1 - 0.12 12.6 0.1 0.84 9.9 0.0 2.3 1 1 1 2 2 2 0 Bacterial PH domain DUF3918 PF13056.6 KLO19453.1 - 6.3 6.5 6.7 2.7 7.7 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) SWIM PF04434.17 KLO19454.1 - 3.5e-07 29.7 0.1 6.2e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger Cecropin PF00272.19 KLO19454.1 - 0.17 11.6 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Cecropin family RCC1 PF00415.18 KLO19455.1 - 2e-36 124.4 2.4 2.6e-11 43.9 0.0 5.3 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KLO19455.1 - 4.8e-16 58.1 9.6 6.3e-06 25.8 0.6 4.2 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 KLO19455.1 - 1e-11 44.5 3.6 1.9e-11 43.7 3.6 1.5 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 KLO19455.1 - 0.0056 17.0 0.6 0.0056 17.0 0.6 2.4 3 0 0 3 3 3 1 C1 domain C1_1 PF00130.22 KLO19455.1 - 0.13 12.1 0.2 0.35 10.8 0.2 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.7 KLO19455.1 - 5.2 7.4 6.6 1.5 9.1 3.2 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain Peptidase_S10 PF00450.22 KLO19457.1 - 3.1e-91 306.9 5.8 3.9e-91 306.5 5.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MCM PF00493.23 KLO19458.1 - 1.2e-100 335.2 0.1 1.8e-100 334.6 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KLO19458.1 - 4.9e-39 133.1 0.1 8.6e-39 132.3 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KLO19458.1 - 4.7e-26 91.0 0.2 3.9e-25 88.1 0.1 2.6 2 0 0 2 2 2 1 MCM AAA-lid domain MCM2_N PF12619.8 KLO19458.1 - 5.8e-13 49.4 13.5 5.8e-13 49.4 13.5 2.7 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 KLO19458.1 - 1.1e-08 35.5 0.1 4.7e-08 33.6 0.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KLO19458.1 - 7.8e-08 31.9 0.0 2.7e-06 26.9 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KLO19458.1 - 1e-05 25.5 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KLO19458.1 - 6.4e-05 22.8 0.1 0.0032 17.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KLO19458.1 - 0.0023 17.7 0.1 0.022 14.4 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.7 KLO19458.1 - 0.034 14.8 0.6 0.092 13.4 0.6 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain GatB_Yqey PF02637.18 KLO19458.1 - 0.091 12.6 0.4 4 7.3 0.2 2.8 2 1 0 2 2 2 0 GatB domain iPGM_N PF06415.13 KLO19458.1 - 0.23 10.9 2.6 0.5 9.8 2.6 1.5 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) zf-TFIIB PF13453.6 KLO19458.1 - 0.48 9.8 1.7 0.93 8.9 1.7 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger UPF0020 PF01170.18 KLO19459.1 - 2.3e-09 37.2 0.0 0.0013 18.4 0.0 2.5 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KLO19459.1 - 4.9e-06 26.4 0.0 0.09 12.5 0.0 2.3 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 KLO19459.1 - 0.016 14.5 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 N-6 DNA Methylase NDUF_B12 PF08122.12 KLO19460.1 - 5.7e-22 77.5 0.9 6.8e-22 77.3 0.9 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family ESSS PF10183.9 KLO19460.1 - 9.8 6.5 7.3 14 6.0 2.4 2.4 1 1 2 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Topoisom_I PF01028.20 KLO19461.1 - 5.6e-101 336.6 7.0 1.6e-100 335.1 7.0 1.9 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KLO19461.1 - 7.3e-95 316.5 0.2 7.3e-95 316.5 0.2 4.0 4 1 1 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KLO19461.1 - 2e-36 123.8 0.3 2e-36 123.8 0.3 2.4 2 0 0 2 2 2 1 C-terminal topoisomerase domain Macoilin PF09726.9 KLO19461.1 - 0.81 8.2 39.4 0.038 12.6 11.1 2.6 2 1 0 2 2 2 0 Macoilin family CD34_antigen PF06365.12 KLO19462.1 - 0.0087 15.7 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF2207 PF09972.9 KLO19464.1 - 0.0006 18.7 0.0 0.00075 18.4 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Stevor PF17410.2 KLO19464.1 - 0.0038 16.8 0.2 0.006 16.2 0.2 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Glycophorin_A PF01102.18 KLO19464.1 - 0.016 15.4 0.3 0.016 15.4 0.3 1.7 2 0 0 2 2 2 0 Glycophorin A Amnionless PF14828.6 KLO19464.1 - 0.017 14.0 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless MGC-24 PF05283.11 KLO19464.1 - 1.5 9.3 14.6 0.057 13.9 7.3 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CE2_N PF17996.1 KLO19465.1 - 3.6e-05 23.7 0.0 8.7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Amnionless PF14828.6 KLO19465.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Amnionless Hamartin PF04388.12 KLO19465.1 - 0.39 9.3 3.6 0.44 9.2 3.6 1.2 1 0 0 1 1 1 0 Hamartin protein Adeno_E3_CR2 PF02439.15 KLO19466.1 - 0.07 12.9 0.9 0.13 12.0 0.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CYYR1 PF10873.8 KLO19466.1 - 0.082 13.4 0.2 0.16 12.4 0.2 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Glyco_hydro_28 PF00295.17 KLO19467.1 - 5.2e-41 140.8 0.4 7.5e-41 140.2 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.13 KLO19467.1 - 0.018 14.3 1.6 0.027 13.7 1.6 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) PEPCK_ATP PF01293.20 KLO19468.1 - 4e-216 718.1 0.0 4.8e-216 717.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KLO19468.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PP2C PF00481.21 KLO19471.1 - 1e-64 218.7 0.2 8.6e-52 176.3 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C AbrB-like PF14250.6 KLO19471.1 - 0.2 11.8 0.1 0.74 9.9 0.0 1.9 2 0 0 2 2 2 0 AbrB-like transcriptional regulator DUF3967 PF13152.6 KLO19471.1 - 0.34 10.7 0.8 6.1 6.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3967) Scs3p PF10261.9 KLO19472.1 - 1.1e-42 146.3 4.2 9.1e-34 117.1 0.0 2.5 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 KLO19472.1 - 0.0022 17.7 0.6 0.0022 17.7 0.6 2.2 2 0 0 2 2 2 1 PAP2 superfamily zf-MYND PF01753.18 KLO19473.1 - 4.3e-08 33.1 13.6 4.3e-08 33.1 13.6 3.1 3 1 1 4 4 4 2 MYND finger zf-MYND PF01753.18 KLO19474.1 - 1.3e-07 31.6 17.6 1.1e-06 28.6 16.8 2.3 1 1 1 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KLO19474.1 - 0.0088 16.3 7.2 0.019 15.3 7.2 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding OrfB_Zn_ribbon PF07282.11 KLO19474.1 - 0.031 14.2 2.5 0.031 14.2 2.5 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-HIT PF04438.16 KLO19474.1 - 2.1 8.3 8.1 5.7 6.9 4.1 2.4 2 0 0 2 2 2 0 HIT zinc finger Med14 PF08638.11 KLO19475.1 - 1.5e-63 213.6 0.3 2.9e-63 212.7 0.3 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 CbiG_mid PF11761.8 KLO19475.1 - 0.073 13.2 0.0 4.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Cobalamin biosynthesis central region HEAT PF02985.22 KLO19476.1 - 4.5e-08 32.7 0.0 0.22 11.9 0.0 4.7 4 0 0 4 4 4 3 HEAT repeat Pkinase PF00069.25 KLO19476.1 - 9.8e-08 31.7 0.0 4.3e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 KLO19476.1 - 8.1e-05 22.7 0.0 0.0074 16.3 0.0 2.4 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 KLO19476.1 - 0.00013 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 KLO19476.1 - 0.00057 20.3 0.0 0.88 10.1 0.0 3.0 2 0 0 2 2 2 2 HEAT-like repeat Kinase-like PF14531.6 KLO19476.1 - 0.022 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-MYND PF01753.18 KLO19478.1 - 1.5e-09 37.8 7.3 1.5e-09 37.8 7.3 3.6 4 0 0 4 4 4 2 MYND finger zf-Mss51 PF13824.6 KLO19478.1 - 0.53 10.4 9.2 0.13 12.4 1.8 2.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Aa_trans PF01490.18 KLO19479.1 - 4.3e-73 246.4 28.8 5.2e-73 246.1 28.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KLO19479.1 - 0.0039 16.3 21.6 0.017 14.2 21.5 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family GHMP_kinases_N PF00288.26 KLO19480.1 - 9e-14 51.5 3.3 2.1e-13 50.3 3.3 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KLO19480.1 - 1.2e-08 35.2 0.0 3.9e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal aGPT-Pplase1 PF18723.1 KLO19482.1 - 1.6e-89 300.1 0.0 2.2e-89 299.6 0.0 1.1 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Chromo PF00385.24 KLO19482.1 - 4.7e-10 39.2 0.0 1.1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Oxidored_q6 PF01058.22 KLO19483.1 - 2.2e-22 79.3 0.1 3.3e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HhH-GPD PF00730.25 KLO19484.1 - 6.8e-11 42.6 0.0 2.8e-10 40.6 0.0 2.1 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PLA2_B PF01735.18 KLO19485.1 - 2.6e-35 121.8 0.0 5.1e-22 77.9 0.0 2.2 2 0 0 2 2 2 2 Lysophospholipase catalytic domain F-box-like PF12937.7 KLO19488.1 - 1.4e-09 37.7 0.4 4.3e-09 36.1 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO19488.1 - 2.4e-08 33.6 0.9 5.2e-08 32.6 0.2 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KLO19488.1 - 0.00012 21.9 0.0 0.00033 20.5 0.0 1.7 1 0 0 1 1 1 1 F-box DASH_Dad2 PF08654.10 KLO19489.1 - 1.8e-07 31.5 0.0 4.1e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 DASH complex subunit Dad2 LPD34 PF18852.1 KLO19489.1 - 0.064 12.8 0.3 0.16 11.5 0.1 1.8 2 1 0 2 2 2 0 Large polyvalent protein associated domain 34 Mac PF12464.8 KLO19490.1 - 1.4e-12 47.7 0.6 3e-12 46.6 0.6 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 KLO19490.1 - 1.7e-09 37.0 8.4 1.7e-09 37.0 8.4 2.8 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KLO19490.1 - 4.2e-05 23.2 6.7 4.2e-05 23.2 6.7 2.7 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase MMS1_N PF10433.9 KLO19491.1 - 6e-154 513.3 0.0 8.7e-154 512.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KLO19491.1 - 2.1e-95 319.8 0.0 7.7e-95 317.9 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region DUF5031 PF16434.5 KLO19491.1 - 0.17 11.0 0.0 0.6 9.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5031) DDRGK PF09756.9 KLO19492.1 - 0.0061 16.2 5.4 0.0091 15.6 5.4 1.3 1 0 0 1 1 1 1 DDRGK domain ABC_membrane PF00664.23 KLO19493.1 - 6.6e-61 206.4 31.6 1.1e-34 120.4 12.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KLO19493.1 - 3e-49 167.1 0.0 7.4e-28 97.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KLO19493.1 - 5.6e-09 35.8 0.2 0.019 14.4 0.0 4.0 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KLO19493.1 - 1.7e-07 31.3 0.2 0.006 16.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KLO19493.1 - 6.8e-07 29.4 0.4 0.043 13.6 0.0 3.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KLO19493.1 - 6.6e-06 26.6 1.2 0.017 15.5 0.1 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KLO19493.1 - 1.1e-05 25.1 0.0 0.073 12.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KLO19493.1 - 7.9e-05 23.2 0.0 0.11 13.0 0.0 3.3 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KLO19493.1 - 0.0005 20.0 0.1 0.76 9.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KLO19493.1 - 0.0005 20.3 0.7 0.86 9.9 0.0 3.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KLO19493.1 - 0.0015 17.9 0.3 0.73 9.1 0.1 2.8 3 0 0 3 3 3 1 Zeta toxin FtsK_SpoIIIE PF01580.18 KLO19493.1 - 0.0018 17.7 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Dynamin_N PF00350.23 KLO19493.1 - 0.0034 17.5 7.4 0.13 12.3 0.9 3.0 3 0 0 3 3 3 2 Dynamin family AAA_15 PF13175.6 KLO19493.1 - 0.01 15.6 0.0 2.3 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 KLO19493.1 - 0.011 15.4 0.5 6.4 6.4 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KLO19493.1 - 0.015 14.9 0.1 0.3 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KLO19493.1 - 0.034 14.3 0.9 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 KLO19493.1 - 0.037 13.2 0.6 9.7 5.3 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain TrwB_AAD_bind PF10412.9 KLO19493.1 - 0.041 12.8 0.1 2.7 6.8 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 KLO19493.1 - 0.064 13.2 0.8 9.6 6.1 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 KLO19493.1 - 0.082 13.1 0.2 5.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KLO19493.1 - 0.087 12.3 0.0 14 5.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KLO19493.1 - 0.2 10.8 1.8 2.2 7.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) cobW PF02492.19 KLO19493.1 - 0.22 11.1 0.5 17 4.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP72 PF08492.12 KLO19493.1 - 6.3 7.3 8.8 12 6.4 0.7 2.5 2 0 0 2 2 2 0 SRP72 RNA-binding domain ABC_membrane PF00664.23 KLO19494.1 - 2.9e-56 191.1 34.0 3.7e-32 112.1 15.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KLO19494.1 - 7.1e-50 169.1 0.0 5.8e-28 98.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KLO19494.1 - 4.5e-09 36.1 0.3 0.0093 15.4 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KLO19494.1 - 2.7e-08 33.9 0.8 0.0047 17.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KLO19494.1 - 1.6e-07 31.5 0.1 0.042 13.6 0.0 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KLO19494.1 - 3.7e-06 26.6 0.0 0.071 12.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KLO19494.1 - 5.5e-06 26.9 2.1 0.01 16.2 0.1 3.5 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KLO19494.1 - 1.9e-05 24.7 1.5 0.088 12.7 0.1 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_23 PF13476.6 KLO19494.1 - 7.8e-05 23.3 5.5 0.11 13.0 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 KLO19494.1 - 0.00022 21.5 0.7 0.85 9.9 0.1 3.3 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KLO19494.1 - 0.0011 18.3 0.0 0.71 9.1 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.23 KLO19494.1 - 0.0022 18.0 7.3 0.13 12.3 0.0 3.6 4 0 0 4 4 4 2 Dynamin family FtsK_SpoIIIE PF01580.18 KLO19494.1 - 0.0064 15.9 1.6 2.9 7.2 0.0 2.7 3 0 0 3 3 2 2 FtsK/SpoIIIE family NACHT PF05729.12 KLO19494.1 - 0.007 16.3 1.6 0.82 9.6 0.0 2.7 3 0 0 3 3 2 1 NACHT domain NB-ARC PF00931.22 KLO19494.1 - 0.0078 15.4 0.2 2.2 7.4 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain AAA_25 PF13481.6 KLO19494.1 - 0.0083 15.7 0.0 0.16 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KLO19494.1 - 0.014 15.6 0.2 5.2 7.3 0.1 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KLO19494.1 - 0.034 13.9 0.8 5.1 6.8 0.1 2.6 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 KLO19494.1 - 0.044 13.8 0.0 8.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KLO19494.1 - 0.059 12.5 0.6 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 KLO19494.1 - 0.066 12.8 0.4 7.8 6.0 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KLO19494.1 - 0.075 12.5 0.0 13 5.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KLO19494.1 - 0.088 13.1 0.1 6.8 7.0 0.1 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TrwB_AAD_bind PF10412.9 KLO19494.1 - 0.12 11.3 0.3 12 4.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PduV-EutP PF10662.9 KLO19494.1 - 0.12 12.1 0.9 26 4.5 0.1 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CDC45 PF02724.14 KLO19494.1 - 0.39 8.9 6.4 0.8 7.9 0.0 2.2 2 0 0 2 2 2 0 CDC45-like protein AAA_15 PF13175.6 KLO19494.1 - 0.42 10.3 6.9 5.5 6.6 0.0 3.5 4 0 0 4 4 4 0 AAA ATPase domain DUF87 PF01935.17 KLO19494.1 - 0.8 9.8 7.9 1.1 9.2 0.1 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain DUF2052 PF09747.9 KLO19494.1 - 4.7 7.3 11.0 14 5.7 1.1 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Tim54 PF11711.8 KLO19494.1 - 5 5.8 7.1 11 4.7 0.1 3.1 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 Cation_efflux PF01545.21 KLO19495.1 - 2e-09 37.5 10.7 3.8e-09 36.6 10.7 1.4 1 1 0 1 1 1 1 Cation efflux family zf-MYND PF01753.18 KLO19496.1 - 1.1e-05 25.4 10.4 2.5e-05 24.2 10.4 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KLO19497.1 - 4.1e-05 23.6 11.7 0.00011 22.2 11.7 1.8 1 0 0 1 1 1 1 MYND finger VanZ PF04892.12 KLO19498.1 - 1e-06 29.4 0.2 1.8e-06 28.6 0.2 1.4 1 0 0 1 1 1 1 VanZ like family TcpE PF12648.7 KLO19498.1 - 0.17 12.4 7.2 0.062 13.8 1.7 2.1 1 1 0 2 2 2 0 TcpE family GtrA PF04138.14 KLO19498.1 - 0.98 9.7 0.0 0.98 9.7 0.0 2.2 1 1 0 2 2 2 0 GtrA-like protein LapA_dom PF06305.11 KLO19498.1 - 5.6 6.9 8.6 0.34 10.8 0.2 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain zf-HC2 PF13490.6 KLO19499.1 - 0.48 10.7 1.6 21 5.5 0.1 3.3 3 0 0 3 3 3 0 Putative zinc-finger IPPT PF01715.17 KLO19500.1 - 1.5e-57 195.1 0.0 8.9e-57 192.5 0.0 2.0 1 1 0 1 1 1 1 IPP transferase AAA_18 PF13238.6 KLO19500.1 - 2e-05 25.2 0.0 0.033 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 KLO19500.1 - 0.007 15.8 0.4 0.03 13.8 0.0 2.0 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KLO19500.1 - 0.026 14.7 0.1 9.6 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain ComS PF17584.2 KLO19501.1 - 0.59 9.7 2.9 0.73 9.4 0.2 2.4 2 0 0 2 2 2 0 Bacillus competence protein S Tim17 PF02466.19 KLO19502.1 - 1.8e-30 105.6 5.8 2.4e-30 105.2 5.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family BTB PF00651.31 KLO19503.1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain TPK_B1_binding PF04265.14 KLO19504.1 - 0.031 14.0 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain Form_Nir_trans PF01226.17 KLO19506.1 - 1e-72 244.3 15.4 1.2e-72 244.1 15.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF1453 PF07301.11 KLO19506.1 - 7.1 6.6 8.0 1.5 8.8 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) PI3_PI4_kinase PF00454.27 KLO19507.1 - 1.1e-37 130.2 0.0 3e-37 128.8 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RRM_1 PF00076.22 KLO19508.1 - 2.3e-10 40.2 0.0 0.00018 21.2 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KLO19508.1 - 0.0064 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Efg1 PF10153.9 KLO19508.1 - 0.31 11.4 0.1 0.31 11.4 0.1 2.3 3 0 0 3 3 3 0 rRNA-processing protein Efg1 KorB_C PF06613.11 KLO19508.1 - 0.34 10.9 1.6 0.47 10.5 0.2 1.9 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain Pkinase PF00069.25 KLO19509.1 - 2.3e-45 155.0 0.0 2e-33 115.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19509.1 - 4.8e-17 62.1 0.0 3.6e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KLO19509.1 - 2.9e-05 23.5 0.0 0.00026 20.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KLO19509.1 - 0.056 13.4 0.5 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Glyco_transf_90 PF05686.12 KLO19511.1 - 2.6e-21 76.0 0.9 4.9e-21 75.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 90 Pkinase_Tyr PF07714.17 KLO19512.1 - 8.4e-16 58.0 0.0 5.1e-15 55.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO19512.1 - 1.5e-14 54.0 0.0 2.3e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Hydrophobin PF01185.18 KLO19514.1 - 1.3e-14 54.5 5.0 1.6e-14 54.3 5.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KLO19516.1 - 5.6e-16 58.9 5.9 6.8e-16 58.7 5.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF5473 PF17567.2 KLO19516.1 - 0.35 11.2 2.5 0.38 11.0 0.2 1.8 1 1 0 2 2 2 0 Family of unknown function (DUF5473) Hydrophobin PF01185.18 KLO19517.1 - 5.3e-16 59.0 4.6 6.4e-16 58.7 4.6 1.0 1 0 0 1 1 1 1 Fungal hydrophobin PepSY_2 PF13670.6 KLO19517.1 - 0.05 13.6 1.2 0.076 13.0 1.2 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Ecm33 PF12454.8 KLO19517.1 - 3.5 7.9 7.6 0.18 12.0 1.7 2.0 2 1 0 2 2 2 0 GPI-anchored cell wall organization protein Hydrophobin PF01185.18 KLO19518.1 - 3.9e-14 53.0 4.8 5e-14 52.7 4.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin RNase_P_pop3 PF08228.11 KLO19519.1 - 5.7e-16 59.0 0.3 2.4e-10 40.7 0.0 3.0 2 1 0 2 2 2 2 RNase P subunit Pop3 PAC2 PF09754.9 KLO19520.1 - 2.1e-24 86.7 0.0 2.6e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 PAC2 family Herpes_MCP PF03122.14 KLO19520.1 - 0.17 9.3 0.0 0.22 9.0 0.0 1.0 1 0 0 1 1 1 0 Herpes virus major capsid protein GMAP PF06540.11 KLO19522.1 - 0.047 13.8 0.0 0.27 11.3 0.0 2.2 2 0 0 2 2 2 0 Galanin message associated peptide (GMAP) PRP8_domainIV PF12134.8 KLO19522.1 - 0.18 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 PRP8 domain IV core SLAC1 PF03595.17 KLO19523.1 - 4.6e-71 239.7 54.5 5.2e-71 239.5 54.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF707 PF05212.12 KLO19524.1 - 0.012 14.8 0.2 0.015 14.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF707) TfoX_N PF04993.13 KLO19524.1 - 0.061 13.5 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 TfoX N-terminal domain NACHT PF05729.12 KLO19527.1 - 8.5e-21 74.6 0.1 7.7e-08 32.4 0.0 4.6 3 2 0 3 3 3 3 NACHT domain AAA_22 PF13401.6 KLO19527.1 - 1.6e-13 51.1 0.0 0.00035 20.8 0.0 4.4 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.6 KLO19527.1 - 4.7e-13 49.9 0.0 0.0021 18.4 0.0 3.9 3 0 0 3 3 3 3 AAA ATPase domain RNA_helicase PF00910.22 KLO19527.1 - 1.1e-08 35.4 0.0 0.22 12.0 0.0 4.1 3 1 0 3 3 3 2 RNA helicase AAA PF00004.29 KLO19527.1 - 9.5e-08 32.5 0.0 0.098 13.1 0.0 4.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KLO19527.1 - 1e-07 31.4 0.0 0.011 15.0 0.0 4.0 4 0 0 4 4 4 2 NB-ARC domain ATPase_2 PF01637.18 KLO19527.1 - 5.4e-07 29.8 0.0 0.029 14.3 0.0 3.9 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea ATPase PF06745.13 KLO19527.1 - 1.2e-06 28.0 0.0 0.028 13.7 0.0 3.7 3 0 0 3 3 3 1 KaiC APS_kinase PF01583.20 KLO19527.1 - 2.5e-06 27.5 0.3 0.26 11.2 0.0 4.0 4 0 0 4 4 3 2 Adenylylsulphate kinase DUF2075 PF09848.9 KLO19527.1 - 2.9e-06 26.8 0.0 0.064 12.5 0.0 3.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KLO19527.1 - 9.3e-06 26.0 0.0 1.8 8.9 0.0 4.1 4 0 0 4 4 3 2 AAA domain Zeta_toxin PF06414.12 KLO19527.1 - 1.4e-05 24.5 0.0 2 7.6 0.0 3.5 3 0 0 3 3 3 2 Zeta toxin cobW PF02492.19 KLO19527.1 - 2.7e-05 23.8 0.6 2.2 7.8 0.0 3.8 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KLO19527.1 - 8.6e-05 22.5 0.0 2.2 8.2 0.0 3.5 3 0 0 3 3 3 1 NTPase AAA_18 PF13238.6 KLO19527.1 - 0.0001 22.8 0.0 5.9 7.5 0.0 4.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KLO19527.1 - 0.0002 21.1 0.1 6.7 6.4 0.0 4.2 4 0 0 4 4 4 0 AAA domain Viral_helicase1 PF01443.18 KLO19527.1 - 0.00024 20.9 0.0 0.82 9.4 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KLO19527.1 - 0.00073 19.4 0.0 14 5.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 KLO19527.1 - 0.00089 18.4 0.1 0.8 8.7 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.17 KLO19527.1 - 0.0012 18.6 0.1 1.8 8.3 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_33 PF13671.6 KLO19527.1 - 0.0016 18.6 0.1 40 4.3 0.0 4.1 4 0 0 4 4 4 0 AAA domain ResIII PF04851.15 KLO19527.1 - 0.0027 17.7 0.0 7.8 6.5 0.0 3.7 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit DnaB_C PF03796.15 KLO19527.1 - 0.0027 17.1 0.0 7.3 5.8 0.0 3.4 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 KLO19527.1 - 0.0038 17.3 0.0 27 4.8 0.0 4.4 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 KLO19527.1 - 0.004 17.1 0.0 17 5.4 0.0 3.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KLO19527.1 - 0.0078 16.0 0.0 7.3 6.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 KLO19527.1 - 0.0091 15.5 0.0 5.4 6.4 0.0 2.7 3 0 0 3 3 2 0 PhoH-like protein AAA_25 PF13481.6 KLO19527.1 - 0.013 15.1 2.4 4.7 6.7 0.1 3.5 3 1 0 3 3 2 0 AAA domain PIF1 PF05970.14 KLO19527.1 - 0.015 14.5 0.0 11 5.1 0.0 3.2 3 0 0 3 3 3 0 PIF1-like helicase GvpD PF07088.11 KLO19527.1 - 0.036 12.7 0.0 12 4.4 0.0 3.1 3 0 0 3 3 3 0 GvpD gas vesicle protein TIP49 PF06068.13 KLO19527.1 - 0.046 12.9 0.0 22 4.1 0.0 3.1 3 0 0 3 3 3 0 TIP49 P-loop domain AAA_7 PF12775.7 KLO19527.1 - 0.059 12.9 0.0 12 5.3 0.0 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KLO19527.1 - 0.062 13.0 0.0 11 5.7 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KLO19527.1 - 0.067 12.6 0.0 10 5.5 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI MeaB PF03308.16 KLO19527.1 - 0.1 11.5 0.0 4.2 6.3 0.0 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 KLO19527.1 - 0.24 10.6 5.8 1 8.5 0.1 4.1 5 1 0 5 5 5 0 KAP family P-loop domain AAA_28 PF13521.6 KLO19527.1 - 0.31 11.3 2.7 6 7.1 0.1 3.0 3 0 0 3 3 2 0 AAA domain F-box_4 PF15966.5 KLO19528.1 - 0.0026 17.6 0.1 0.0052 16.6 0.1 1.5 1 0 0 1 1 1 1 F-box TACC_C PF05010.14 KLO19528.1 - 0.025 14.4 2.5 0.041 13.7 2.5 1.4 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2207 PF09972.9 KLO19528.1 - 0.03 13.1 0.3 0.046 12.5 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LETM1 PF07766.13 KLO19529.1 - 2.4e-25 89.4 0.8 4.2e-12 46.0 0.0 2.1 1 1 1 2 2 2 2 LETM1-like protein DUF4887 PF16228.5 KLO19532.1 - 8.7 6.5 12.1 1 9.5 4.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) TPR_2 PF07719.17 KLO19533.1 - 5.8e-38 125.9 23.2 0.00033 20.6 0.2 18.3 19 0 0 19 19 18 6 Tetratricopeptide repeat TPR_8 PF13181.6 KLO19533.1 - 9.5e-30 100.3 24.8 0.0016 18.5 0.3 17.8 20 0 0 20 20 18 6 Tetratricopeptide repeat TPR_14 PF13428.6 KLO19533.1 - 3e-28 96.1 38.8 0.011 16.5 0.2 19.2 12 5 7 19 19 19 6 Tetratricopeptide repeat TPR_16 PF13432.6 KLO19533.1 - 9.6e-28 96.6 36.9 2e-07 31.6 0.4 11.4 12 1 2 14 14 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 KLO19533.1 - 4.4e-27 92.8 21.7 0.0075 16.0 0.0 14.0 16 0 0 16 16 13 6 Tetratricopeptide repeat TPR_12 PF13424.6 KLO19533.1 - 1.2e-26 92.8 35.9 4.6e-06 26.8 0.2 12.3 9 3 5 14 14 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 KLO19533.1 - 6e-24 84.3 35.7 4.1e-05 24.0 0.1 13.1 8 3 6 15 15 15 5 Tetratricopeptide repeat TPR_17 PF13431.6 KLO19533.1 - 1.9e-19 68.6 19.1 3.8e-05 23.8 0.3 13.4 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_11 PF13414.6 KLO19533.1 - 3.3e-14 52.3 26.9 0.00035 20.2 0.2 12.7 14 1 1 15 15 14 4 TPR repeat TPR_9 PF13371.6 KLO19533.1 - 2.1e-12 47.0 21.3 0.004 17.3 0.0 9.9 8 3 3 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.6 KLO19533.1 - 3.5e-12 45.4 16.8 0.03 14.4 0.0 12.0 13 0 0 13 13 11 1 Tetratricopeptide repeat TPR_6 PF13174.6 KLO19533.1 - 3e-09 36.9 21.3 0.84 10.4 0.0 14.5 17 0 0 17 17 14 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KLO19533.1 - 7e-09 35.8 10.9 0.00098 19.3 0.0 8.3 5 3 4 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KLO19533.1 - 3.4e-07 30.0 18.9 0.13 11.6 10.1 6.0 5 1 1 6 6 6 2 MalT-like TPR region DUF3808 PF10300.9 KLO19533.1 - 4.1e-05 22.5 0.3 0.15 10.8 0.1 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3808) PknG_TPR PF16918.5 KLO19533.1 - 0.00094 18.0 3.3 0.0033 16.2 0.1 3.3 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat DUF3856 PF12968.7 KLO19533.1 - 0.0024 18.0 1.9 3.2 7.8 0.1 4.6 4 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_21 PF09976.9 KLO19533.1 - 0.0029 17.3 22.8 0.0047 16.7 0.4 6.0 5 2 0 6 6 6 1 Tetratricopeptide repeat-like domain HrpB1_HrpK PF09613.10 KLO19533.1 - 0.0033 17.1 4.4 6.2 6.5 0.0 5.1 4 1 1 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) Fis1_TPR_C PF14853.6 KLO19533.1 - 0.0041 17.2 0.1 24 5.1 0.0 5.0 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat SPO22 PF08631.10 KLO19533.1 - 0.0082 15.7 0.4 0.064 12.7 0.1 2.8 1 1 1 2 2 2 1 Meiosis protein SPO22/ZIP4 like Clathrin PF00637.20 KLO19533.1 - 0.021 14.7 0.9 9.8 6.0 0.0 3.9 4 0 0 4 4 3 0 Region in Clathrin and VPS TPR_20 PF14561.6 KLO19533.1 - 0.022 15.1 16.8 0.4 11.0 0.2 7.0 7 1 1 8 8 5 0 Tetratricopeptide repeat BTAD PF03704.17 KLO19533.1 - 0.03 14.7 18.2 1.2 9.6 0.2 7.0 5 3 2 7 7 6 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 KLO19533.1 - 0.043 13.7 21.6 2.5 8.1 0.1 8.5 10 0 0 10 10 8 0 Tetratricopeptide repeat RPN7 PF10602.9 KLO19533.1 - 0.055 13.2 9.1 13 5.4 0.0 5.4 6 0 0 6 6 6 0 26S proteasome subunit RPN7 ChAPs PF09295.10 KLO19533.1 - 0.19 10.7 3.0 17 4.3 0.0 3.9 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) FAT PF02259.23 KLO19533.1 - 0.89 8.7 5.4 21 4.2 0.0 4.4 4 0 0 4 4 4 0 FAT domain SNAP PF14938.6 KLO19533.1 - 2.5 7.4 17.2 0.31 10.4 0.3 5.5 5 2 1 6 6 6 0 Soluble NSF attachment protein, SNAP F-box PF00646.33 KLO19534.1 - 7.4e-06 25.7 0.5 1.8e-05 24.5 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO19534.1 - 0.00073 19.4 0.4 0.0018 18.1 0.4 1.6 1 0 0 1 1 1 1 F-box-like YvbH_ext PF11724.8 KLO19534.1 - 0.0012 19.1 0.0 0.0038 17.5 0.0 1.8 1 0 0 1 1 1 1 YvbH-like oligomerisation region F-box_4 PF15966.5 KLO19534.1 - 0.063 13.2 0.4 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 F-box DUF3094 PF11293.8 KLO19534.1 - 0.16 11.7 0.2 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Lipase_GDSL_2 PF13472.6 KLO19535.1 - 1.2e-16 61.7 0.8 1.7e-16 61.1 0.8 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KLO19535.1 - 0.00016 21.7 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DSPc PF00782.20 KLO19537.1 - 0.00013 21.8 0.1 0.00028 20.7 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KLO19537.1 - 0.0056 16.4 0.1 0.0098 15.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 KLO19537.1 - 0.026 14.6 0.0 0.072 13.2 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF442 PF04273.13 KLO19537.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Y_phosphatase PF00102.27 KLO19537.1 - 0.14 11.7 0.4 0.34 10.5 0.4 1.7 1 1 0 1 1 1 0 Protein-tyrosine phosphatase Serinc PF03348.15 KLO19537.1 - 0.2 10.6 0.1 0.3 10.0 0.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TAP42 PF04177.12 KLO19537.1 - 0.25 10.4 0.3 0.48 9.5 0.3 1.4 1 0 0 1 1 1 0 TAP42-like family Y_phosphatase3 PF13350.6 KLO19537.1 - 0.38 10.7 0.8 0.59 10.0 0.1 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family Chitin_synth_2 PF03142.15 KLO19538.1 - 2.1e-253 841.7 0.0 2.7e-253 841.4 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KLO19538.1 - 8.6e-15 55.2 4.3 8.6e-15 55.2 4.3 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KLO19538.1 - 2.4e-14 53.8 0.0 1.1e-13 51.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KLO19538.1 - 0.00062 19.3 0.1 0.067 12.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KLO19538.1 - 0.027 14.3 0.0 0.42 10.4 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 FtsX PF02687.21 KLO19538.1 - 9.7 6.7 13.1 4.7 7.7 0.0 3.4 3 0 0 3 3 3 0 FtsX-like permease family F-box PF00646.33 KLO19539.1 - 3.2e-05 23.7 0.2 6.5e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO19539.1 - 0.0012 18.7 0.1 0.0022 17.8 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KLO19539.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 F-box F-box PF00646.33 KLO19540.1 - 0.0011 18.8 0.4 0.0027 17.5 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO19540.1 - 0.023 14.6 0.4 0.058 13.3 0.4 1.7 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 KLO19540.1 - 0.047 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 KLO19541.1 - 0.029 14.3 1.3 0.25 11.3 1.3 2.4 1 1 0 1 1 1 0 F-box-like MFS_1 PF07690.16 KLO19543.1 - 7.5e-51 173.1 44.3 1.4e-50 172.2 43.3 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KLO19543.1 - 2.4e-19 69.2 20.5 3.1e-19 68.8 20.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KLO19543.1 - 1.6e-10 40.5 11.4 1.6e-10 40.5 11.4 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter HlyIII PF03006.20 KLO19543.1 - 9.2e-05 22.3 5.7 0.00019 21.2 0.2 2.6 1 1 0 2 2 2 1 Haemolysin-III related DUF3185 PF11381.8 KLO19543.1 - 0.0064 16.5 3.5 0.0064 16.5 3.5 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3185) DUF3043 PF11241.8 KLO19543.1 - 0.14 12.1 0.0 0.51 10.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF3522 PF12036.8 KLO19543.1 - 0.8 10.0 7.3 0.23 11.7 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) Ten1_2 PF15490.6 KLO19544.1 - 1.6e-05 24.6 0.0 1.9e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Ten1 PF12658.7 KLO19544.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.6 1 1 0 1 1 1 0 Telomere capping, CST complex subunit zf-MYND PF01753.18 KLO19545.1 - 1.2e-10 41.3 14.2 1.2e-10 41.3 14.2 1.9 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 KLO19545.1 - 0.54 10.4 7.4 1.5 9.0 7.4 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 F-box-like PF12937.7 KLO19546.1 - 0.035 14.0 0.8 0.12 12.2 0.8 2.1 1 1 0 1 1 1 0 F-box-like F-box PF00646.33 KLO19547.1 - 9.3e-05 22.2 1.0 0.00026 20.8 0.4 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KLO19547.1 - 0.0036 17.2 0.2 0.011 15.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO19548.1 - 0.00057 19.7 0.2 0.0012 18.6 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO19548.1 - 0.0013 18.5 0.2 0.0028 17.5 0.2 1.5 1 0 0 1 1 1 1 F-box-like YL1 PF05764.13 KLO19548.1 - 0.0021 18.2 7.3 0.0038 17.4 7.3 1.4 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 KLO19548.1 - 0.4 8.9 11.5 0.55 8.5 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DivIC PF04977.15 KLO19550.1 - 0.09 12.6 1.0 11 5.9 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator TSC22 PF01166.18 KLO19550.1 - 0.3 11.4 1.7 6.6 7.1 0.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family TPR_MLP1_2 PF07926.12 KLO19550.1 - 0.74 9.9 4.3 1.4 9.0 4.3 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.15 KLO19550.1 - 4.6 7.4 5.8 32 4.7 0.9 2.5 2 0 0 2 2 2 0 Basic region leucine zipper F-box PF00646.33 KLO19551.1 - 2.4e-06 27.2 1.6 4.2e-06 26.5 0.3 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KLO19551.1 - 0.00037 20.3 1.2 0.00078 19.3 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KLO19551.1 - 0.0066 16.3 1.1 0.024 14.5 0.1 2.3 2 0 0 2 2 2 1 F-box SWI-SNF_Ssr4 PF08549.10 KLO19551.1 - 0.8 8.3 4.8 1.1 7.9 4.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) CDC45 PF02724.14 KLO19551.1 - 1.2 7.3 5.4 2.1 6.5 5.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C1_2 PF03051.15 KLO19552.1 - 6.5e-150 499.7 0.2 7.5e-150 499.5 0.2 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KLO19552.1 - 1.6e-07 31.6 0.0 0.0074 16.4 0.0 2.5 2 0 0 2 2 2 2 Papain family cysteine protease zf-C4_ClpX PF06689.13 KLO19553.1 - 0.042 13.7 0.1 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger Gelsolin PF00626.22 KLO19554.1 - 0.0016 18.3 0.2 0.0073 16.2 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat Med27 PF11571.8 KLO19555.1 - 2.5e-13 50.2 0.1 4.9e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Mediator complex subunit 27 RasGAP PF00616.19 KLO19555.1 - 0.024 14.3 4.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase DUF5308 PF17233.2 KLO19555.1 - 0.28 11.4 5.1 9.5 6.4 0.0 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5308) DUF4552 PF15089.6 KLO19556.1 - 1.3 8.0 3.8 1.7 7.6 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) DOCK_N PF16172.5 KLO19558.1 - 1.7e-117 392.5 0.0 3.1e-117 391.7 0.0 1.5 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KLO19558.1 - 6.6e-76 256.1 0.1 2.1e-75 254.4 0.1 1.7 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KLO19558.1 - 1.6e-50 171.7 0.0 1.8e-49 168.2 0.0 2.7 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins WD40 PF00400.32 KLO19559.1 - 4e-29 100.2 9.1 3.9e-07 30.6 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19559.1 - 1e-08 35.4 0.3 0.027 14.8 0.0 4.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 KLO19559.1 - 0.00071 19.1 1.6 0.0023 17.5 0.5 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF5046) WD40_like PF17005.5 KLO19559.1 - 0.0016 17.9 0.0 0.31 10.3 0.0 2.7 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 KLO19559.1 - 0.002 16.8 1.4 2.2 6.8 0.1 3.7 3 1 2 5 5 5 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KLO19559.1 - 0.0021 17.7 1.4 0.0059 16.2 0.7 2.0 1 1 1 2 2 2 1 PQQ-like domain BBS2_Mid PF14783.6 KLO19559.1 - 0.011 15.8 0.1 11 6.1 0.0 4.4 4 2 2 6 6 6 0 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 KLO19559.1 - 0.038 13.9 0.1 20 5.4 0.0 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat LSM PF01423.22 KLO19560.1 - 1.9e-15 56.3 0.3 2.4e-15 56.0 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KLO19560.1 - 0.019 15.1 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Peptidase_C1_2 PF03051.15 KLO19561.1 - 1.2e-156 522.0 0.1 1.4e-156 521.7 0.1 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KLO19561.1 - 1.1e-07 32.1 0.0 0.0027 17.8 0.0 2.6 2 0 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.13 KLO19561.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family Macoilin PF09726.9 KLO19563.1 - 8.2e-05 21.4 7.7 8.8e-05 21.3 7.7 1.1 1 0 0 1 1 1 1 Macoilin family ATG16 PF08614.11 KLO19563.1 - 0.00018 21.8 6.1 0.00026 21.3 6.1 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ADIP PF11559.8 KLO19563.1 - 0.0043 17.1 6.6 0.0086 16.2 6.6 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Cep57_CLD PF14073.6 KLO19563.1 - 0.005 16.9 6.0 0.0088 16.1 6.0 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 Golgin_A5 PF09787.9 KLO19563.1 - 0.035 13.6 8.0 0.055 12.9 8.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 KLO19563.1 - 0.088 11.7 6.7 0.12 11.3 6.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 KLO19563.1 - 1 9.1 9.2 2.2 8.1 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMPIT PF07851.13 KLO19563.1 - 2.1 7.5 4.5 2.8 7.1 4.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.25 KLO19564.1 - 4.8e-66 222.8 0.0 9.1e-66 221.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19564.1 - 3.2e-38 131.5 0.0 3.4e-37 128.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO19564.1 - 0.00023 21.2 3.3 0.21 11.5 0.0 3.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO19564.1 - 0.0016 17.8 0.0 0.0037 16.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Gp58 PF07902.11 KLO19564.1 - 0.051 11.9 2.1 0.083 11.2 2.1 1.2 1 0 0 1 1 1 0 gp58-like protein Prominin PF05478.11 KLO19564.1 - 5.8 4.7 5.7 8.2 4.2 5.7 1.2 1 0 0 1 1 1 0 Prominin Tom6 PF17112.5 KLO19566.1 - 0.13 11.8 0.9 0.96 9.0 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal F-box PF00646.33 KLO19567.1 - 5.3e-05 23.0 0.3 0.00015 21.5 0.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO19567.1 - 0.0049 16.7 0.2 0.012 15.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like zinc_ribbon_6 PF14599.6 KLO19567.1 - 0.08 13.0 0.4 1.8 8.6 0.3 2.6 2 0 0 2 2 2 0 Zinc-ribbon DUF4934 PF16288.5 KLO19567.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) Ribosomal_S7 PF00177.21 KLO19568.1 - 3.8e-37 127.2 4.9 4.6e-37 126.9 4.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Hemopexin PF00045.19 KLO19569.1 - 0.0011 18.8 1.6 4.1 7.4 0.0 4.1 4 0 0 4 4 4 2 Hemopexin Mononeg_mRNAcap PF14318.6 KLO19570.1 - 0.0056 16.0 0.3 0.012 14.8 0.2 1.6 1 1 1 2 2 2 1 Mononegavirales mRNA-capping region V PS_pyruv_trans PF04230.13 KLO19570.1 - 0.049 13.5 0.1 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide pyruvyl transferase DUF1764 PF08576.10 KLO19570.1 - 0.097 13.6 0.1 0.28 12.1 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) T2SSG PF08334.11 KLO19578.1 - 0.089 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Zn_clus PF00172.18 KLO19579.1 - 0.00022 21.3 7.3 0.00043 20.3 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_6 PF13405.6 KLO19581.1 - 8.1e-11 40.9 0.2 5.9e-05 22.7 0.0 2.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KLO19581.1 - 2.6e-10 39.1 0.7 0.00021 20.6 0.1 3.4 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KLO19581.1 - 4.5e-10 39.8 0.0 3.2e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KLO19581.1 - 1.1e-07 32.0 0.0 0.027 14.8 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KLO19581.1 - 6.2e-05 22.8 0.2 0.088 12.7 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KLO19581.1 - 0.0035 16.8 0.0 0.56 9.8 0.0 2.7 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.13 KLO19581.1 - 0.015 15.3 0.2 9.4 6.4 0.1 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) Muted PF14942.6 KLO19581.1 - 0.031 14.6 0.1 0.04 14.2 0.1 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Glyco_hydro_3_C PF01915.22 KLO19583.1 - 2e-66 223.9 0.1 3.1e-66 223.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KLO19583.1 - 1.2e-38 133.3 0.0 2e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KLO19583.1 - 5.4e-21 74.5 0.1 1.1e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KLO19583.1 - 2e-11 43.9 0.0 4.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 PA14 domain tRNA-synt_1b PF00579.25 KLO19585.1 - 4.8e-23 81.9 0.0 1.1e-22 80.7 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) PRTase_2 PF15609.6 KLO19586.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase eRF1_2 PF03464.15 KLO19587.1 - 5.7e-42 143.2 0.0 1e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KLO19587.1 - 7.3e-36 123.1 0.1 1.4e-35 122.1 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KLO19587.1 - 1.6e-10 41.1 0.0 2.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KLO19587.1 - 4.8e-08 33.4 0.0 8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KLO19587.1 - 0.0016 18.7 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 p450 PF00067.22 KLO19588.1 - 4.7e-64 216.8 0.0 6.2e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KLO19588.1 - 9.7e-25 87.4 0.0 1.8e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KLO19588.1 - 1.4e-20 74.0 0.0 2.6e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KLO19588.1 - 2.5e-09 37.7 0.0 6.2e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.11 KLO19588.1 - 0.073 13.3 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 NrdI Flavodoxin like Halo_GVPC PF05465.13 KLO19589.1 - 0.0067 16.7 0.5 0.015 15.5 0.0 1.9 2 1 0 2 2 2 1 Halobacterial gas vesicle protein C (GVPC) repeat DUF1359 PF07097.11 KLO19589.1 - 0.062 13.5 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) Robl_LC7 PF03259.17 KLO19589.1 - 0.16 11.7 0.0 0.21 11.4 0.0 1.4 1 1 0 1 1 1 0 Roadblock/LC7 domain H_PPase PF03030.16 KLO19591.1 - 1.7 7.2 7.7 0.23 10.0 2.3 1.9 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase Orf78 PF06024.12 KLO19591.1 - 2.6 8.4 6.6 2.8 8.3 0.0 3.6 3 1 1 4 4 4 0 Orf78 (ac78) Shugoshin_N PF07558.11 KLO19592.1 - 3.1e-09 36.5 1.6 8.1e-09 35.2 1.6 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KLO19592.1 - 2.2e-08 33.7 6.1 1.1e-07 31.5 6.1 2.3 1 0 0 1 1 1 1 Shugoshin C terminus GIT_CC PF16559.5 KLO19592.1 - 0.022 14.6 1.8 0.061 13.2 1.8 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1087 PF06465.13 KLO19592.1 - 0.046 13.8 0.9 0.31 11.1 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) SnAC PF14619.6 KLO19592.1 - 1.4 9.6 0.0 1.4 9.6 0.0 4.2 4 0 0 4 4 4 0 Snf2-ATP coupling, chromatin remodelling complex KASH_CCD PF14662.6 KLO19592.1 - 2 8.2 12.2 0.067 13.0 6.1 1.5 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 KLO19592.1 - 3.2 8.4 9.7 0.16 12.6 2.8 2.1 2 0 0 2 2 2 0 Initiation control protein YabA C2 PF00168.30 KLO19594.1 - 1.2e-13 51.2 0.0 2.1e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF454 PF04304.13 KLO19595.1 - 0.2 11.7 0.2 0.35 10.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF454) DBR1 PF05011.13 KLO19596.1 - 2.4e-42 144.7 0.0 3.6e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KLO19596.1 - 1.9e-09 38.3 0.6 2.9e-09 37.7 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KLO19596.1 - 0.044 14.0 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain KcnmB2_inactiv PF09303.10 KLO19596.1 - 0.15 11.9 0.1 0.45 10.4 0.1 1.8 1 0 0 1 1 1 0 KCNMB2, ball and chain domain WW PF00397.26 KLO19598.1 - 0.00018 21.5 2.3 0.0006 19.9 2.3 2.0 1 0 0 1 1 1 1 WW domain PTS_2-RNA PF01885.16 KLO19598.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 2 0 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Caa3_CtaG PF09678.10 KLO19598.1 - 0.29 10.5 5.0 0.048 13.1 0.4 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF1634 PF07843.11 KLO19598.1 - 1 9.4 4.4 0.53 10.4 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1634) DUF202 PF02656.15 KLO19598.1 - 4.9 7.7 6.7 0.81 10.2 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF2207 PF09972.9 KLO19598.1 - 6.1 5.5 6.4 5.2 5.7 5.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) LRR_4 PF12799.7 KLO19599.1 - 0.0023 18.3 15.0 1.9 9.0 0.0 5.4 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KLO19599.1 - 0.091 13.4 11.3 1.1 10.1 0.5 5.0 5 1 0 5 5 5 0 Leucine Rich Repeat XRCC4 PF06632.12 KLO19599.1 - 0.3 9.9 6.1 0.53 9.1 5.6 1.5 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 CDC45 PF02724.14 KLO19599.1 - 0.67 8.2 2.2 0.94 7.7 1.6 1.5 2 0 0 2 2 2 0 CDC45-like protein TFIIF_alpha PF05793.12 KLO19599.1 - 1.4 7.4 14.0 2.1 6.9 14.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LRR_6 PF13516.6 KLO19599.1 - 1.7 8.9 19.9 0.19 11.9 0.9 6.2 8 0 0 8 8 8 0 Leucine Rich repeat HATPase_c PF02518.26 KLO19600.1 - 2.7e-51 172.8 0.0 3.3e-24 85.5 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KLO19600.1 - 3.9e-48 162.3 0.6 2.5e-25 88.8 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 KLO19600.1 - 1.8e-17 63.1 1.3 2.7e-10 40.2 0.0 3.2 2 1 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KLO19600.1 - 1.1e-05 25.6 0.1 0.026 14.8 0.0 3.2 3 0 0 3 3 3 2 PAS fold HATPase_c_3 PF13589.6 KLO19600.1 - 9.3e-05 22.3 0.1 0.009 15.8 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 KLO19600.1 - 0.00045 20.4 0.0 0.12 12.6 0.0 3.8 3 0 0 3 3 3 1 PAS domain HATPase_c_5 PF14501.6 KLO19600.1 - 0.00051 19.9 0.0 0.34 10.9 0.0 2.5 2 0 0 2 2 2 2 GHKL domain PAS_8 PF13188.7 KLO19600.1 - 0.00074 19.5 0.0 0.1 12.6 0.0 3.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KLO19600.1 - 0.0084 16.1 0.0 0.067 13.2 0.0 2.5 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.6 KLO19600.1 - 0.012 15.9 0.0 0.18 12.1 0.0 2.6 2 0 0 2 2 2 0 GAF domain PAS_3 PF08447.12 KLO19600.1 - 0.074 13.3 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 PAS fold BRCT_2 PF16589.5 KLO19601.1 - 1.5e-10 41.3 0.0 3.5e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Kv2channel PF03521.14 KLO19601.1 - 0.3 10.4 5.8 0.13 11.6 1.2 2.0 1 1 1 2 2 2 0 Kv2 voltage-gated K+ channel MFS_1 PF07690.16 KLO19602.1 - 1.2e-40 139.5 43.5 5.5e-40 137.4 41.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO19602.1 - 8.7e-09 34.7 23.9 2.2e-08 33.4 9.8 3.1 1 1 1 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KLO19602.1 - 4.8e-08 31.9 11.9 2e-07 29.8 10.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4231 PF14015.6 KLO19602.1 - 2.7 8.5 8.5 3 8.3 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Cyclase PF04199.13 KLO19603.1 - 2.1e-14 53.9 0.1 3.4e-14 53.3 0.1 1.5 1 1 0 1 1 1 1 Putative cyclase Pkinase PF00069.25 KLO19604.1 - 1.6e-47 162.1 0.0 2.6e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19604.1 - 2.9e-24 85.7 0.0 5.3e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KLO19604.1 - 0.0067 15.5 0.1 0.0099 14.9 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KLO19604.1 - 0.44 10.1 7.3 0.33 10.5 0.4 3.4 2 2 0 3 3 3 0 RIO1 family BRCT_2 PF16589.5 KLO19605.1 - 1.1e-06 28.9 0.0 2.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KLO19605.1 - 0.0032 17.8 0.0 0.0067 16.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Myb_DNA-bind_2 PF08914.11 KLO19605.1 - 0.011 15.9 1.6 0.048 13.8 1.6 2.1 1 1 0 1 1 1 0 Rap1 Myb domain LIG3_BRCT PF16759.5 KLO19605.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain NIBRIN_BRCT_II PF16508.5 KLO19605.1 - 0.19 12.1 0.6 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein HSP70 PF00012.20 KLO19606.1 - 0.0017 16.7 0.4 0.0041 15.4 0.1 1.7 2 0 0 2 2 2 1 Hsp70 protein Peptidase_M23 PF01551.22 KLO19606.1 - 0.044 14.0 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 Sas10_Utp3 PF04000.15 KLO19608.1 - 3.4e-11 43.6 0.1 8.4e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family CEND1 PF15677.5 KLO19608.1 - 0.11 13.1 0.1 0.3 11.6 0.1 1.7 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 RNA_pol_Rbc25 PF08292.12 KLO19609.1 - 0.0071 16.6 0.2 0.011 15.9 0.1 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 DUF5427 PF10310.9 KLO19609.1 - 1.1 8.1 9.3 1.5 7.7 9.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4554 PF15091.6 KLO19609.1 - 1.2 7.9 5.2 1.6 7.5 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) zf-AN1 PF01428.16 KLO19609.1 - 3.4 7.9 7.3 14 5.9 1.3 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger zf-primase PF09329.11 KLO19611.1 - 0.0047 16.7 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 Primase zinc finger DUF4497 PF14924.6 KLO19611.1 - 0.089 13.3 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) Lactamase_B_2 PF12706.7 KLO19612.1 - 1.1e-30 106.6 0.1 1.5e-30 106.3 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KLO19612.1 - 3.2e-10 40.1 0.0 7.3e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KLO19612.1 - 0.59 10.1 4.3 1.1 9.3 1.5 2.7 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily DUF5082 PF16888.5 KLO19613.1 - 0.006 16.9 3.2 0.015 15.5 3.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) SPX PF03105.19 KLO19613.1 - 0.01 15.8 0.4 0.016 15.2 0.4 1.3 1 0 0 1 1 1 0 SPX domain Baculo_PEP_C PF04513.12 KLO19613.1 - 0.066 13.3 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 KLO19613.1 - 0.29 10.7 6.5 0.23 11.0 5.1 1.5 2 0 0 2 2 2 0 Intermediate filament protein UPF0242 PF06785.11 KLO19613.1 - 1.3 9.1 3.7 5.1 7.2 3.6 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4200 PF13863.6 KLO19613.1 - 1.6 9.1 7.0 3.4 8.1 1.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HAUS6_N PF14661.6 KLO19613.1 - 1.6 8.2 4.0 2.2 7.8 1.9 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.15 KLO19613.1 - 3.2 7.6 7.9 2.7 7.8 0.3 3.2 2 1 0 3 3 3 0 Septum formation initiator CCDC-167 PF15188.6 KLO19613.1 - 3.8 7.9 6.3 0.74 10.2 1.9 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 adh_short_C2 PF13561.6 KLO19614.1 - 1.8e-46 158.6 0.7 3.2e-46 157.8 0.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO19614.1 - 1.5e-43 148.5 0.9 4.5e-43 147.0 0.9 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO19614.1 - 2.8e-06 27.4 0.1 4.2e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO19614.1 - 0.0056 16.2 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KLO19614.1 - 0.041 13.2 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KLO19614.1 - 0.05 13.5 1.7 0.065 13.1 0.4 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KLO19614.1 - 0.083 12.9 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Dak1 PF02733.17 KLO19614.1 - 0.097 11.6 1.3 1 8.2 0.3 2.6 3 0 0 3 3 3 0 Dak1 domain AdoHcyase_NAD PF00670.21 KLO19614.1 - 0.13 12.4 0.4 0.26 11.3 0.4 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MRP-S33 PF08293.11 KLO19615.1 - 1e-29 102.6 0.1 1.4e-29 102.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 SUV3_C PF12513.8 KLO19616.1 - 2.4e-14 53.0 0.1 6.1e-14 51.7 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KLO19616.1 - 1.2e-10 41.7 0.0 2.9e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KLO19616.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 Zn_clus PF00172.18 KLO19617.1 - 0.0019 18.3 12.3 0.0029 17.7 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KLO19618.1 - 0.0014 18.7 7.3 0.0023 18.0 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KLO19619.1 - 2.1e-23 83.1 0.1 2.6e-22 79.5 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO19619.1 - 2e-11 44.1 0.5 2.7e-09 37.2 0.2 2.7 1 1 1 2 2 2 1 NAD(P)H-binding KR PF08659.10 KLO19619.1 - 2.8e-05 24.1 0.0 4.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO19619.1 - 0.00014 21.4 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO19619.1 - 0.0048 15.9 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KLO19619.1 - 0.061 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KLO19619.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 KLO19619.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glycos_transf_1 PF00534.20 KLO19624.1 - 4.6e-24 84.9 0.0 2.7e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KLO19624.1 - 3.5e-20 72.7 0.2 5.5e-20 72.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KLO19624.1 - 1.4e-10 41.7 0.0 1.3e-09 38.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KLO19624.1 - 1.1e-08 35.7 0.0 2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KLO19624.1 - 0.0083 16.5 0.0 0.027 14.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Pribosyltran_N PF13793.6 KLO19626.1 - 2.2e-47 159.8 0.2 8.1e-47 158.0 0.1 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KLO19626.1 - 1.3e-34 119.9 0.9 5.2e-30 104.8 0.3 2.7 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KLO19626.1 - 2.5e-18 66.1 0.2 9.1e-17 61.0 0.1 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KLO19626.1 - 3.3e-06 26.7 0.0 7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KLO19626.1 - 0.11 12.0 0.1 0.27 10.7 0.1 1.6 2 0 0 2 2 2 0 Phosphoribosyl transferase Hist_deacetyl PF00850.19 KLO19627.1 - 4.3e-81 272.8 0.0 5.3e-81 272.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF5320 PF17253.2 KLO19627.1 - 0.68 11.0 17.3 1.1 10.3 5.7 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5320) MgtE PF01769.16 KLO19628.1 - 1.8e-39 134.9 22.2 1.5e-22 80.2 7.5 3.3 1 1 2 3 3 3 2 Divalent cation transporter Ada3 PF10198.9 KLO19629.1 - 4.7e-28 98.0 0.0 4.7e-28 98.0 0.0 2.6 3 1 0 3 3 3 1 Histone acetyltransferases subunit 3 Herpes_UL25 PF01499.16 KLO19629.1 - 0.031 12.8 0.3 0.031 12.8 0.3 1.5 2 0 0 2 2 2 0 Herpesvirus UL25 family F-box-like PF12937.7 KLO19630.1 - 0.0037 17.1 0.0 0.0087 15.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like DIOX_N PF14226.6 KLO19631.1 - 3.5e-20 72.9 0.1 8.3e-20 71.7 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO19631.1 - 3.3e-13 50.0 0.0 8.1e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amino_oxidase PF01593.24 KLO19632.1 - 1.2e-48 166.6 0.0 7.5e-35 121.1 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KLO19632.1 - 4.1e-11 42.9 0.0 1.3e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KLO19632.1 - 0.14 12.8 0.1 0.37 11.4 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KLO19632.1 - 0.16 11.2 0.5 0.24 10.6 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain VWA PF00092.28 KLO19633.1 - 1.8e-06 28.3 0.0 3.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KLO19633.1 - 0.00012 22.6 0.0 0.00029 21.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.8 KLO19633.1 - 0.00023 21.1 0.0 0.00049 20.0 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Integrin_beta PF00362.18 KLO19633.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Integrin beta chain VWA domain VWA PF00092.28 KLO19635.1 - 1.4e-08 35.2 0.4 2.5e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KLO19635.1 - 1.4e-05 25.6 0.1 4.9e-05 23.9 0.1 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.8 KLO19635.1 - 1.8e-05 24.7 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Integrin_beta PF00362.18 KLO19635.1 - 0.0003 20.6 0.1 0.0093 15.6 0.1 2.2 1 1 0 1 1 1 1 Integrin beta chain VWA domain Dyp_perox PF04261.12 KLO19635.1 - 0.14 11.1 0.0 2.1 7.3 0.0 2.4 3 0 0 3 3 3 0 Dyp-type peroxidase family RNA_polI_A34 PF08208.11 KLO19636.1 - 9.5e-23 81.4 1.5 9.5e-23 81.4 1.5 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 AP3D1 PF06375.11 KLO19636.1 - 1.8 8.8 15.4 0.71 10.1 4.8 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Rtf2 PF04641.12 KLO19636.1 - 6.9 5.9 14.7 0.054 12.9 0.7 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger HhH-GPD PF00730.25 KLO19637.1 - 1.2e-19 70.7 0.0 2.5e-19 69.7 0.0 1.5 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KLO19637.1 - 6.7e-08 32.0 0.0 2e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KLO19637.1 - 0.0044 17.6 0.2 0.87 10.2 0.0 2.6 2 1 0 2 2 2 1 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 KLO19637.1 - 0.18 12.2 2.2 0.37 11.2 2.2 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Phos_pyr_kin PF08543.12 KLO19638.1 - 4.2e-82 275.2 0.5 9.8e-81 270.7 0.5 2.1 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KLO19638.1 - 5.3e-44 150.5 0.2 7.3e-44 150.1 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KLO19638.1 - 0.003 16.9 0.0 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 pfkB family carbohydrate kinase HK PF02110.15 KLO19638.1 - 0.0048 16.3 0.1 3 7.1 0.0 2.5 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family tRNA-synt_1b PF00579.25 KLO19639.1 - 3e-72 243.4 0.0 3.7e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Mak10 PF04112.13 KLO19640.1 - 5.9e-52 175.6 0.0 1.2e-51 174.6 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Zn_clus PF00172.18 KLO19641.1 - 0.0015 18.6 9.7 0.0028 17.8 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain STI1 PF17830.1 KLO19642.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 STI1 domain DUF5053 PF16476.5 KLO19643.1 - 0.2 11.3 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) FG-GAP PF01839.23 KLO19645.1 - 0.2 11.8 1.7 0.72 10.0 0.4 2.2 2 0 0 2 2 2 0 FG-GAP repeat Peptidase_M50B PF13398.6 KLO19646.1 - 2.8e-57 193.6 18.6 2.8e-57 193.6 18.6 1.3 2 0 0 2 2 2 1 Peptidase M50B-like TMEM171 PF15471.6 KLO19646.1 - 0.3 10.0 2.1 0.51 9.3 2.1 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 zf-C2H2 PF00096.26 KLO19647.1 - 2.2e-12 46.7 14.6 0.00045 20.5 1.2 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KLO19647.1 - 2.6e-08 33.9 13.3 3.8e-05 23.9 0.4 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KLO19647.1 - 6.3e-08 32.8 13.4 0.014 16.2 0.8 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KLO19647.1 - 9.6e-05 22.3 7.6 0.007 16.3 0.1 3.3 3 1 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KLO19647.1 - 0.0025 18.4 8.2 0.12 13.0 3.6 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-met PF12874.7 KLO19647.1 - 0.0031 17.9 6.1 2.3 8.7 0.4 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KLO19647.1 - 0.0039 17.4 2.5 0.014 15.7 2.4 1.7 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-TRAF PF02176.18 KLO19647.1 - 0.018 15.8 2.4 0.018 15.8 2.4 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 KLO19647.1 - 0.023 14.8 3.4 1 9.5 0.1 2.8 1 1 2 3 3 3 0 Aberrant zinc-finger Furin-like_2 PF15913.5 KLO19647.1 - 0.12 12.6 4.6 0.41 10.8 1.6 2.1 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich zf-C2H2_jaz PF12171.8 KLO19647.1 - 0.47 10.8 8.7 16 5.9 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KLO19647.1 - 1.2 8.9 6.8 4 7.3 0.1 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type FIIND PF13553.6 KLO19649.1 - 0.013 14.9 0.2 0.022 14.2 0.2 1.2 1 0 0 1 1 1 0 Function to find TMEM171 PF15471.6 KLO19650.1 - 0.01 14.8 1.6 0.024 13.6 1.2 1.7 1 1 1 2 2 2 0 Transmembrane protein family 171 OppC_N PF12911.7 KLO19652.1 - 0.029 14.3 1.9 0.066 13.2 1.9 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C TMEM51 PF15345.6 KLO19652.1 - 0.069 13.0 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 UCH PF00443.29 KLO19657.1 - 1.5e-42 145.9 0.0 2.7e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KLO19657.1 - 2.9e-27 94.8 11.7 1.3e-21 76.7 1.8 2.8 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KLO19657.1 - 5.5e-24 83.7 3.8 6.1e-23 80.3 0.7 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 KLO19657.1 - 2.1e-23 81.8 1.3 3.4e-11 42.8 0.5 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KLO19657.1 - 3.4e-16 59.7 0.1 1.4e-14 54.5 0.0 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-C2HE PF16278.5 KLO19657.1 - 0.01 16.3 0.3 1.4 9.5 0.1 3.3 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger Brix PF04427.18 KLO19658.1 - 1.5e-40 139.4 0.2 2.2e-40 138.9 0.2 1.2 1 0 0 1 1 1 1 Brix domain NOA36 PF06524.12 KLO19658.1 - 0.73 9.1 5.9 0.98 8.7 5.9 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KLO19658.1 - 6.1 6.5 5.8 13 5.4 5.8 1.6 1 0 0 1 1 1 0 FAM176 family F-box-like PF12937.7 KLO19659.1 - 0.0023 17.8 0.0 0.0054 16.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like zf-C2H2 PF00096.26 KLO19661.1 - 4.1e-07 30.1 10.5 0.00021 21.6 1.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO19661.1 - 0.00072 20.2 10.4 0.16 12.9 2.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KLO19661.1 - 0.0032 17.8 3.5 0.0032 17.8 3.5 2.4 3 0 0 3 3 3 1 Zinc-finger double domain DUF3844 PF12955.7 KLO19661.1 - 0.11 12.6 0.7 0.2 11.8 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) zf-H2C2_5 PF13909.6 KLO19661.1 - 2 8.3 5.4 4.6 7.1 1.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Hat1_N PF10394.9 KLO19663.1 - 5.6e-55 186.0 0.4 1.1e-54 185.0 0.4 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KLO19663.1 - 0.00034 20.8 0.0 0.00073 19.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KLO19663.1 - 0.0012 19.5 0.3 0.029 15.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KLO19663.1 - 0.0048 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 KLO19663.1 - 0.043 13.5 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 MOZ/SAS family Ribonuclease_3 PF00636.26 KLO19664.1 - 1.9e-42 144.1 0.0 1.4e-20 73.8 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KLO19664.1 - 2.7e-24 85.7 0.1 8.1e-14 51.9 0.0 4.2 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KLO19664.1 - 1e-17 64.0 0.0 2.1e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KLO19664.1 - 1.5e-16 60.7 0.0 4.1e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO19664.1 - 2.5e-15 56.9 0.0 5.3e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KLO19664.1 - 3.7e-13 49.6 0.0 1.1e-12 48.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Phosducin PF02114.16 KLO19665.1 - 2.5e-09 36.5 0.0 4e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Phosducin NADH-G_4Fe-4S_3 PF10588.9 KLO19667.1 - 0.051 13.1 2.9 5.5 6.6 0.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF4554 PF15091.6 KLO19668.1 - 1.2 7.9 6.2 1.4 7.8 6.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) LMBR1 PF04791.16 KLO19668.1 - 1.7 7.5 4.0 1.9 7.3 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Band_3_cyto PF07565.13 KLO19668.1 - 2 8.1 8.4 2.5 7.8 8.4 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.17 KLO19668.1 - 4.2 6.0 6.5 4.7 5.9 6.5 1.0 1 0 0 1 1 1 0 Presenilin DUF3774 PF12609.8 KLO19668.1 - 6.1 7.9 8.5 13 6.9 8.5 1.7 1 1 0 1 1 1 0 Wound-induced protein Porin_4 PF13609.6 KLO19669.1 - 0.0058 16.4 0.3 0.059 13.1 0.1 2.1 2 0 0 2 2 2 1 Gram-negative porin ShlB PF03865.13 KLO19669.1 - 0.013 15.0 1.6 1.1 8.7 0.1 2.4 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Lipoprotein_6 PF01441.19 KLO19669.1 - 0.16 12.0 6.8 0.33 10.9 6.8 1.5 1 0 0 1 1 1 0 Lipoprotein CENP-F_leu_zip PF10473.9 KLO19669.1 - 0.16 12.0 12.8 0.49 10.4 12.8 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fil_haemagg_2 PF13332.6 KLO19669.1 - 0.68 10.0 11.3 4.8 7.3 3.6 2.8 2 0 0 2 2 2 0 Hemagglutinin repeat HMMR_N PF15905.5 KLO19669.1 - 1 8.8 16.2 0.072 12.6 10.4 1.9 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Exonuc_VII_L PF02601.15 KLO19669.1 - 1 8.9 14.4 0.16 11.6 6.8 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit GED PF02212.18 KLO19669.1 - 2.1 8.5 5.9 5.8 7.1 3.0 2.6 2 0 0 2 2 2 0 Dynamin GTPase effector domain zf-C4H2 PF10146.9 KLO19669.1 - 4.1 7.6 10.5 0.31 11.3 1.0 2.8 3 0 0 3 3 3 0 Zinc finger-containing protein GAS PF13851.6 KLO19669.1 - 4.6 6.5 17.6 1.4 8.2 13.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spectrin PF00435.21 KLO19669.1 - 6.4 7.3 15.1 0.4 11.2 3.0 3.6 2 1 0 3 3 3 0 Spectrin repeat DHHC PF01529.20 KLO19671.1 - 2.1e-30 105.6 11.0 2.1e-30 105.6 11.0 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase MARVEL PF01284.23 KLO19671.1 - 0.75 9.8 11.9 0.68 10.0 1.1 2.5 2 0 0 2 2 2 0 Membrane-associating domain LRR_4 PF12799.7 KLO19672.1 - 8 7.0 5.8 59 4.3 0.0 4.4 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) OPA3 PF07047.12 KLO19673.1 - 1e-43 148.1 0.0 1.3e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) betaPIX_CC PF16523.5 KLO19673.1 - 0.0098 15.7 0.5 0.02 14.7 0.5 1.5 1 0 0 1 1 1 1 betaPIX coiled coil BLOC1_2 PF10046.9 KLO19673.1 - 0.015 15.6 0.5 0.038 14.3 0.2 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.6 KLO19673.1 - 0.063 13.3 0.3 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 FlxA-like protein Cytochrom_NNT PF03264.14 KLO19673.1 - 0.16 11.7 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region MbeD_MobD PF04899.12 KLO19673.1 - 0.17 12.0 0.4 0.17 12.0 0.4 1.9 2 0 0 2 2 2 0 MbeD/MobD like SlyX PF04102.12 KLO19673.1 - 6.7 7.4 6.2 2.1 9.0 0.2 2.8 3 1 1 4 4 4 0 SlyX Cellulase PF00150.18 KLO19675.1 - 2.5e-12 46.8 0.0 5e-08 32.7 0.1 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 KLO19675.1 - 1.4e-10 41.5 0.1 2.5e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 KLO19675.1 - 0.083 12.5 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Glyco_hydro_14 PF01373.17 KLO19675.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 IPK PF03770.16 KLO19676.1 - 1.2e-42 146.1 0.0 1.6e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase GP67 PF17634.2 KLO19676.1 - 0.0069 16.8 9.7 0.017 15.6 9.7 1.6 1 0 0 1 1 1 1 Gene product 67 Phage_Gp23 PF10669.9 KLO19676.1 - 0.094 13.1 1.5 0.17 12.3 1.5 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) NOA36 PF06524.12 KLO19676.1 - 0.17 11.2 10.7 0.29 10.4 10.7 1.3 1 0 0 1 1 1 0 NOA36 protein RNase_H2_suC PF08615.11 KLO19676.1 - 0.29 11.3 1.9 1.7 8.8 1.5 2.1 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FAM176 PF14851.6 KLO19676.1 - 0.62 9.7 7.0 0.076 12.7 2.4 1.8 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 KLO19676.1 - 1.1 7.3 9.3 1.5 6.8 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KLO19676.1 - 2.1 7.4 12.5 4.3 6.4 12.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) S-antigen PF05756.11 KLO19676.1 - 2.5 8.5 5.5 6.6 7.2 5.5 1.7 1 0 0 1 1 1 0 S-antigen protein PBP1_TM PF14812.6 KLO19676.1 - 3 8.3 10.2 0.4 11.1 5.9 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 KLO19676.1 - 4.3 7.4 10.2 0.086 12.9 2.2 2.1 3 0 0 3 3 3 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 KLO19676.1 - 6.6 6.4 13.5 0.18 11.5 7.0 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Zn_clus PF00172.18 KLO19677.1 - 1.8e-05 24.8 12.9 2.4e-05 24.4 12.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_3 PF01764.25 KLO19678.1 - 5.8e-07 29.5 0.0 4.1e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 KLO19678.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) CNPase PF05881.12 KLO19678.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Dynactin_p22 PF07426.11 KLO19679.1 - 1.4e-16 60.8 0.0 2.1e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 DUF4600 PF15372.6 KLO19679.1 - 0.012 16.0 0.2 0.074 13.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) FapA PF03961.13 KLO19679.1 - 0.05 12.2 0.0 0.064 11.9 0.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A SesA PF17107.5 KLO19679.1 - 0.055 13.7 0.2 0.13 12.5 0.2 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Laminin_I PF06008.14 KLO19679.1 - 0.057 13.1 1.0 1.3 8.7 2.2 2.2 2 1 0 2 2 2 0 Laminin Domain I ALIX_LYPXL_bnd PF13949.6 KLO19679.1 - 0.066 12.5 1.8 0.32 10.2 1.2 2.0 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV GAT PF03127.14 KLO19679.1 - 0.096 13.0 0.5 1.9 8.8 0.0 2.8 3 1 0 3 3 3 0 GAT domain Lebercilin PF15619.6 KLO19679.1 - 0.13 11.9 4.2 0.52 9.9 3.5 2.1 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Sec20 PF03908.13 KLO19679.1 - 0.18 11.7 0.1 1.5 8.8 0.1 2.1 2 0 0 2 2 2 0 Sec20 RCDG1 PF15725.5 KLO19679.1 - 0.33 11.4 4.2 0.34 11.3 2.6 1.8 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein eIF2A PF08662.11 KLO19680.1 - 7.5e-70 234.8 0.0 9.8e-69 231.1 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KLO19680.1 - 7.9e-05 22.9 0.0 18 5.7 0.0 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KLO19680.1 - 0.0043 17.9 0.1 0.85 10.6 0.0 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Proteasome_A_N PF10584.9 KLO19680.1 - 0.025 14.2 6.4 2.9 7.7 0.2 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 KLO19680.1 - 0.03 14.3 1.6 7.6 6.6 0.1 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 KLO19680.1 - 0.044 12.8 0.0 0.51 9.3 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region CDV3 PF15359.6 KLO19680.1 - 0.5 10.9 2.1 1.3 9.5 2.1 1.7 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Zn_clus PF00172.18 KLO19681.1 - 0.0099 16.0 8.4 0.0099 16.0 8.4 2.1 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_4 PF12799.7 KLO19682.1 - 0.041 14.3 0.5 0.041 14.3 0.5 3.5 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KLO19683.1 - 3.5e-07 30.0 1.5 1.3e-06 28.2 1.5 2.1 1 1 0 1 1 1 1 F-box-like TA_inhibitor PF17574.2 KLO19683.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) Myb_DNA-bind_2 PF08914.11 KLO19684.1 - 4.5e-12 46.0 2.6 1.7e-11 44.1 2.6 2.0 1 0 0 1 1 1 1 Rap1 Myb domain Rap1_C PF11626.8 KLO19684.1 - 0.038 14.1 1.9 0.12 12.5 0.0 2.6 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain adh_short_C2 PF13561.6 KLO19685.1 - 1.2e-56 191.9 0.0 1.7e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO19685.1 - 8e-47 159.2 0.2 1e-46 158.9 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO19685.1 - 1.1e-11 44.9 0.1 1.5e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO19685.1 - 7.6e-05 22.3 0.0 0.0002 20.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KLO19686.1 - 1e-59 201.9 0.0 1.3e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO19686.1 - 1.6e-52 177.8 0.0 1.9e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KLO19686.1 - 6.5e-15 55.5 0.1 8.3e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO19686.1 - 0.00023 20.7 0.1 0.00036 20.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KLO19686.1 - 0.017 15.7 0.5 0.035 14.7 0.5 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3280 PF11684.8 KLO19686.1 - 0.061 13.7 0.2 0.096 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) THF_DHG_CYH_C PF02882.19 KLO19686.1 - 0.092 12.1 0.2 0.21 10.9 0.1 1.6 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 KLO19686.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ALC PF17527.2 KLO19687.1 - 0.058 13.0 0.3 0.071 12.8 0.3 1.1 1 0 0 1 1 1 0 Phage ALC protein HSP70 PF00012.20 KLO19688.1 - 1.6e-57 195.0 6.9 3.1e-40 138.0 0.2 3.2 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KLO19688.1 - 5.7e-06 25.4 0.0 2e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 MreB/Mbl protein DprA_WH PF17782.1 KLO19688.1 - 0.0086 16.2 1.0 0.69 10.1 0.0 3.3 2 1 0 2 2 2 1 DprA winged helix domain F-box-like PF12937.7 KLO19689.1 - 0.00016 21.5 0.1 0.00075 19.3 0.1 2.2 1 1 0 1 1 1 1 F-box-like PLDc_2 PF13091.6 KLO19690.1 - 4.3e-23 81.7 0.0 1.2e-15 57.6 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KLO19690.1 - 0.00012 22.0 0.5 0.074 13.3 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif GPI-anchored PF10342.9 KLO19691.1 - 0.085 13.6 0.0 0.12 13.2 0.0 1.3 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 KLO19692.1 - 0.03 15.1 0.0 0.072 13.9 0.0 1.6 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1418 PF07214.12 KLO19692.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) DUF202 PF02656.15 KLO19692.1 - 0.055 13.9 0.1 2.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) TMEM51 PF15345.6 KLO19692.1 - 0.061 13.1 0.6 0.39 10.5 0.0 2.4 3 0 0 3 3 3 0 Transmembrane protein 51 LapA_dom PF06305.11 KLO19692.1 - 0.097 12.5 0.6 0.19 11.6 0.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4328 PF14219.6 KLO19692.1 - 0.13 11.8 0.4 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) MotA_ExbB PF01618.16 KLO19693.1 - 0.022 14.5 0.1 0.039 13.7 0.1 1.4 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family DUF5305 PF17231.2 KLO19694.1 - 0.24 10.8 4.0 0.31 10.4 3.5 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5305) GPI-anchored PF10342.9 KLO19695.1 - 8.1e-05 23.3 0.5 8.1e-05 23.3 0.5 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Claudin_2 PF13903.6 KLO19695.1 - 0.92 9.2 3.5 1.8 8.3 0.4 2.5 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Cytadhesin_P30 PF07271.11 KLO19696.1 - 0.013 15.1 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Herpes_gE PF02480.16 KLO19696.1 - 0.03 13.1 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4366 PF14283.6 KLO19696.1 - 0.04 14.0 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2755 PF10954.8 KLO19696.1 - 0.066 13.1 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) Halogen_Hydrol PF10112.9 KLO19696.1 - 0.078 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein MHC2-interact PF09307.10 KLO19696.1 - 0.089 12.8 0.2 0.27 11.2 0.0 1.8 1 1 2 3 3 3 0 CLIP, MHC2 interacting Amnionless PF14828.6 KLO19696.1 - 0.17 10.7 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 Amnionless SKG6 PF08693.10 KLO19696.1 - 0.37 10.2 3.1 0.96 8.9 3.1 1.8 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 KLO19696.1 - 4.9 7.2 5.8 17 5.5 5.8 1.9 1 1 0 1 1 1 0 LPXTG cell wall anchor motif TMEM51 PF15345.6 KLO19697.1 - 0.0031 17.4 0.1 0.0049 16.7 0.1 1.4 1 1 0 1 1 1 1 Transmembrane protein 51 EphA2_TM PF14575.6 KLO19697.1 - 0.0037 18.1 0.0 0.0053 17.6 0.0 1.4 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain PalH PF08733.10 KLO19697.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 TMEM154 PF15102.6 KLO19698.1 - 0.001 19.0 0.4 0.001 19.0 0.4 2.1 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 KLO19698.1 - 0.0084 17.0 0.0 0.018 15.9 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF5305 PF17231.2 KLO19698.1 - 0.0098 15.3 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Baculo_11_kDa PF06143.11 KLO19698.1 - 0.01 15.4 0.2 0.027 14.1 0.2 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family TMEM51 PF15345.6 KLO19698.1 - 0.024 14.5 0.5 0.069 13.0 0.0 1.8 1 1 1 2 2 2 0 Transmembrane protein 51 Adeno_E3_CR2 PF02439.15 KLO19698.1 - 0.11 12.3 2.3 0.19 11.5 2.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1180 PF06679.12 KLO19698.1 - 3.2 8.1 9.2 12 6.3 9.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 KLO19699.1 - 0.059 14.3 0.0 0.098 13.6 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Nitrate_red_gam PF02665.14 KLO19699.1 - 0.075 12.6 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF4328 PF14219.6 KLO19699.1 - 0.097 12.2 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF4381 PF14316.6 KLO19700.1 - 0.023 14.9 1.7 0.049 13.9 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMEM190 PF15431.6 KLO19700.1 - 0.028 14.5 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 190 LPG_synthase_TM PF03706.13 KLO19700.1 - 0.053 13.1 0.2 0.08 12.5 0.2 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Keratin_B2 PF01500.17 KLO19700.1 - 0.41 10.6 3.4 0.62 10.0 3.4 1.2 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein SKG6 PF08693.10 KLO19700.1 - 1.5 8.3 5.1 3 7.3 5.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 KLO19702.1 - 0.02 14.8 0.3 0.02 14.8 0.3 2.3 1 1 0 2 2 2 0 TMEM154 protein family OPA3 PF07047.12 KLO19702.1 - 0.062 13.1 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Saf_2TM PF18303.1 KLO19702.1 - 0.068 12.8 0.2 0.16 11.5 0.1 1.6 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain RCR PF12273.8 KLO19702.1 - 0.23 12.1 1.4 0.56 10.9 0.5 2.1 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Macoilin PF09726.9 KLO19702.1 - 0.49 8.9 2.5 0.62 8.6 2.5 1.1 1 0 0 1 1 1 0 Macoilin family DLIC PF05783.11 KLO19702.1 - 1.4 7.7 8.6 1.8 7.3 8.6 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF2730 PF10805.8 KLO19703.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) TMEM154 PF15102.6 KLO19703.1 - 0.072 13.0 4.3 0.17 11.8 4.3 1.7 1 1 0 1 1 1 0 TMEM154 protein family DUF3405 PF11885.8 KLO19704.1 - 0.043 12.4 0.0 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Med13_C PF06333.12 KLO19706.1 - 7.9 5.6 15.2 14 4.8 15.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain F-box-like PF12937.7 KLO19707.1 - 6.3e-07 29.2 2.0 1.8e-06 27.8 2.0 1.9 1 0 0 1 1 1 1 F-box-like PRIMA1 PF16101.5 KLO19708.1 - 0.0094 16.0 1.5 2.4 8.2 0.5 2.5 2 0 0 2 2 2 2 Proline-rich membrane anchor 1 LRRC37AB_C PF14914.6 KLO19708.1 - 0.17 11.8 0.0 0.43 10.5 0.0 1.6 1 1 1 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain SWI-SNF_Ssr4 PF08549.10 KLO19708.1 - 2.5 6.6 7.2 3.4 6.2 7.2 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Alpha_GJ PF03229.13 KLO19708.1 - 9.1 6.9 15.3 0.11 13.1 2.1 2.5 1 1 1 2 2 2 0 Alphavirus glycoprotein J GREB1 PF15782.5 KLO19709.1 - 4.7 4.2 7.5 5.9 3.9 7.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Cnn_1N PF07989.11 KLO19711.1 - 5.5e-24 84.1 9.6 5.5e-24 84.1 9.6 13.3 6 2 5 13 13 13 4 Centrosomin N-terminal motif 1 HalX PF08663.10 KLO19711.1 - 0.0022 18.3 7.0 0.0022 18.3 7.0 15.0 8 5 8 17 17 17 2 HalX domain ADIP PF11559.8 KLO19711.1 - 0.024 14.7 0.7 0.024 14.7 0.7 11.4 2 2 10 12 12 12 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 KLO19711.1 - 3.7 6.9 159.4 0.027 13.8 12.0 9.6 3 2 7 10 10 10 0 Growth-arrest specific micro-tubule binding MFS_1 PF07690.16 KLO19712.1 - 2e-38 132.2 29.4 2e-38 132.2 29.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily WD40 PF00400.32 KLO19716.1 - 2.9e-23 81.7 16.1 6.2e-07 30.0 2.4 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat NACHT PF05729.12 KLO19716.1 - 4.6e-14 52.7 0.0 1.1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KLO19716.1 - 7.8e-07 29.6 0.0 2.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ANAPC4_WD40 PF12894.7 KLO19716.1 - 6.1e-06 26.4 0.1 0.45 10.9 0.1 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2075 PF09848.9 KLO19716.1 - 0.0025 17.1 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KLO19716.1 - 0.0031 16.8 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KLO19716.1 - 0.0046 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KLO19716.1 - 0.0053 16.0 0.0 0.0092 15.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KLO19716.1 - 0.11 13.0 0.1 0.38 11.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KLO19716.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KLO19716.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KLO19716.1 - 0.14 12.7 0.0 8.5 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KLO19716.1 - 0.18 12.1 0.0 0.47 10.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 KLO19718.1 - 3.4e-27 94.1 24.5 1.8e-08 34.9 0.9 8.7 8 0 0 8 8 7 5 WD domain, G-beta repeat NACHT PF05729.12 KLO19718.1 - 4.7e-19 68.9 0.0 7.1e-08 32.5 0.0 3.4 2 2 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO19718.1 - 1.9e-13 51.2 0.1 4.1e-07 30.6 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain ANAPC4_WD40 PF12894.7 KLO19718.1 - 6.5e-10 39.2 0.3 0.016 15.5 0.1 5.5 4 1 2 6 6 5 2 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 KLO19718.1 - 5.6e-09 36.5 0.0 0.0021 18.5 0.0 4.2 4 2 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KLO19718.1 - 8.5e-07 28.4 0.0 0.012 14.8 0.0 2.7 3 0 0 3 3 3 2 NB-ARC domain Zeta_toxin PF06414.12 KLO19718.1 - 1.1e-06 28.1 0.0 0.051 12.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF2075 PF09848.9 KLO19718.1 - 4.4e-06 26.2 0.0 0.074 12.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 KLO19718.1 - 6.2e-06 26.2 0.1 0.074 12.9 0.0 2.7 2 0 0 2 2 2 2 Adenylylsulphate kinase KAP_NTPase PF07693.14 KLO19718.1 - 9.4e-06 25.1 1.4 0.16 11.2 0.1 4.0 4 0 0 4 4 4 2 KAP family P-loop domain AAA_22 PF13401.6 KLO19718.1 - 2.7e-05 24.5 0.0 0.18 12.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KLO19718.1 - 6e-05 23.4 0.0 0.43 11.0 0.0 3.0 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 KLO19718.1 - 0.00016 21.7 0.0 0.33 10.8 0.0 2.6 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KLO19718.1 - 0.00037 20.9 0.1 1.5 9.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain DnaB_C PF03796.15 KLO19718.1 - 0.0053 16.1 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 KLO19718.1 - 0.0073 15.9 0.5 2.2 7.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 KLO19718.1 - 0.01 15.0 0.0 0.74 9.0 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain DUF1186 PF06685.11 KLO19718.1 - 0.011 15.1 1.3 0.045 13.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1186) Viral_helicase1 PF01443.18 KLO19718.1 - 0.012 15.3 0.0 4.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KLO19718.1 - 0.014 15.3 0.0 7.4 6.4 0.0 2.8 3 0 0 3 3 2 0 NTPase PD40 PF07676.12 KLO19718.1 - 0.019 14.9 1.5 20 5.3 0.1 4.8 5 0 0 5 5 4 0 WD40-like Beta Propeller Repeat AAA_18 PF13238.6 KLO19718.1 - 0.023 15.2 0.0 12 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KLO19718.1 - 0.034 13.5 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KLO19718.1 - 0.037 13.7 0.0 9.1 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KLO19718.1 - 0.042 13.9 0.0 8.8 6.3 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KLO19718.1 - 0.065 13.2 0.0 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 KLO19718.1 - 0.071 13.3 0.5 18 5.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KLO19718.1 - 0.075 12.7 0.1 17 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KLO19718.1 - 0.11 13.0 0.4 12 6.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain Parvo_NS1 PF01057.17 KLO19718.1 - 0.12 11.4 0.0 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 cobW PF02492.19 KLO19718.1 - 0.14 11.8 0.1 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PIF1 PF05970.14 KLO19718.1 - 0.17 11.0 0.0 3 6.9 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Proteasome_A_N PF10584.9 KLO19718.1 - 0.91 9.3 3.9 52 3.6 0.0 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature WD40 PF00400.32 KLO19719.1 - 2.4e-33 113.6 37.4 3.1e-08 34.2 0.0 9.4 10 0 0 10 10 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19719.1 - 2.1e-14 53.6 2.9 0.00032 21.0 0.0 7.5 5 2 1 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KLO19719.1 - 1.8e-05 24.7 0.0 0.00015 21.7 0.0 2.3 1 1 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KLO19719.1 - 8e-05 21.7 0.1 0.84 8.5 0.0 4.2 3 2 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KLO19719.1 - 0.0039 17.6 0.0 0.03 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KLO19719.1 - 0.029 14.8 0.0 0.18 12.2 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KLO19719.1 - 0.047 12.8 0.0 0.093 11.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KLO19719.1 - 0.054 12.7 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain WD40_like PF17005.5 KLO19719.1 - 0.084 12.2 0.1 8 5.7 0.0 3.4 4 0 0 4 4 4 0 WD40-like domain RNA_helicase PF00910.22 KLO19719.1 - 0.096 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Torsin PF06309.11 KLO19719.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Torsin PD40 PF07676.12 KLO19719.1 - 1.2 9.1 7.5 8.1 6.5 0.0 5.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Pkinase PF00069.25 KLO19720.1 - 3.9e-42 144.5 0.0 1.2e-21 77.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19720.1 - 1.2e-14 54.2 0.0 1.7e-09 37.4 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase PrmA PF06325.13 KLO19720.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pyr_redox_2 PF07992.14 KLO19722.1 - 3.3e-63 213.6 1.9 5.4e-63 213.0 1.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KLO19722.1 - 2.1e-32 111.7 0.1 4e-32 110.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KLO19722.1 - 1.7e-21 76.6 5.3 6.3e-18 65.1 0.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KLO19722.1 - 1.6e-19 70.3 3.8 7.3e-19 68.1 3.8 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KLO19722.1 - 2.6e-12 46.2 3.3 5.7e-06 25.3 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 KLO19722.1 - 3.3e-11 43.2 0.6 1.4e-10 41.2 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO19722.1 - 5.9e-08 32.2 0.4 6.8e-06 25.4 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.6 KLO19722.1 - 1.8e-07 30.6 0.6 3.2e-07 29.8 0.0 1.7 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KLO19722.1 - 6.1e-06 26.4 0.8 6.1e-06 26.4 0.8 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KLO19722.1 - 1.6e-05 24.2 1.9 7.3e-05 22.0 0.4 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KLO19722.1 - 0.0003 20.1 0.1 0.00061 19.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KLO19722.1 - 0.0013 18.1 0.6 0.22 10.8 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KLO19722.1 - 0.0018 18.0 9.0 0.0028 17.3 0.5 2.7 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KLO19722.1 - 0.0066 15.7 5.8 0.33 10.2 0.2 2.7 2 1 1 3 3 3 2 FAD binding domain 3HCDH_N PF02737.18 KLO19722.1 - 0.0081 16.1 2.9 0.2 11.6 0.1 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KLO19722.1 - 0.012 16.0 0.2 3.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KLO19722.1 - 0.013 14.5 0.3 0.049 12.7 0.0 1.9 2 1 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KLO19722.1 - 0.14 11.5 0.7 2.6 7.4 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KLO19722.1 - 0.16 11.9 0.1 0.16 11.9 0.1 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KLO19722.1 - 0.3 10.3 2.8 5.1 6.3 0.1 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase WD40 PF00400.32 KLO19723.1 - 1.9e-23 82.3 7.8 7.6e-05 23.4 0.0 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO19723.1 - 8.3e-14 51.7 0.0 0.086 13.2 0.0 6.3 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KLO19723.1 - 1.1e-08 35.1 0.1 1.1e-07 31.9 0.0 2.7 2 1 0 2 2 2 1 NACHT domain Ge1_WD40 PF16529.5 KLO19723.1 - 0.0021 17.1 0.3 4 6.3 0.0 3.9 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Calcipressin PF04847.12 KLO19727.1 - 3.6e-29 101.8 0.1 2.1e-27 96.0 0.1 2.2 1 1 0 1 1 1 1 Calcipressin MA3 PF02847.17 KLO19730.1 - 1.3e-26 92.8 0.5 2.7e-26 91.8 0.5 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 KLO19730.1 - 2.1e-13 50.4 2.8 8.8e-13 48.4 0.1 2.4 2 1 0 2 2 2 1 MIF4G domain ArfA PF03889.13 KLO19731.1 - 0.07 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A DUF4191 PF13829.6 KLO19732.1 - 0.97 8.7 2.3 1.6 8.1 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Mtc PF03820.17 KLO19736.1 - 0.077 12.0 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Tricarboxylate carrier DUF4199 PF13858.6 KLO19738.1 - 0.27 11.6 5.1 0.52 10.7 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) NOA36 PF06524.12 KLO19742.1 - 1.6 8.0 10.5 0.066 12.5 3.9 1.9 2 0 0 2 2 2 0 NOA36 protein CENP-B_dimeris PF09026.10 KLO19742.1 - 2.6 8.5 13.1 8.2 6.9 13.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Syntaphilin PF15290.6 KLO19745.1 - 0.057 13.1 2.7 0.054 13.1 1.8 1.3 1 1 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Sirohm_synth_C PF14823.6 KLO19746.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal NACHT PF05729.12 KLO19747.1 - 4.1e-18 65.8 0.8 4.3e-13 49.5 0.0 3.4 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO19747.1 - 4.4e-10 40.2 0.2 0.00029 21.3 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KLO19747.1 - 3.9e-07 30.4 0.0 3.4e-05 24.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KLO19747.1 - 2.9e-05 24.5 0.0 0.00041 20.8 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KLO19747.1 - 0.004 16.4 0.1 0.13 11.4 0.0 2.9 2 1 0 2 2 2 1 NB-ARC domain Parvo_NS1 PF01057.17 KLO19747.1 - 0.0052 15.9 1.2 1.8 7.6 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 KLO19747.1 - 0.0093 16.5 0.0 0.25 11.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KLO19747.1 - 0.014 15.8 0.3 1.1 9.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.14 KLO19747.1 - 0.035 13.4 0.0 2.1 7.5 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.6 KLO19747.1 - 0.072 12.8 0.2 0.35 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KLO19747.1 - 0.1 12.5 3.0 0.51 10.2 0.4 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase RAD51_interact PF15696.5 KLO19747.1 - 0.15 12.1 0.1 4.6 7.4 0.0 2.5 2 0 0 2 2 2 0 RAD51 interacting motif NACHT PF05729.12 KLO19749.1 - 1e-16 61.3 0.1 2.8e-11 43.6 0.0 3.3 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KLO19749.1 - 1.8e-10 41.5 2.0 0.00032 21.1 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KLO19749.1 - 7.7e-09 35.9 0.0 1.4e-05 25.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 KLO19749.1 - 4.6e-06 25.9 0.0 0.0028 16.8 0.0 2.5 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KLO19749.1 - 0.00022 20.5 0.0 0.026 13.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 KLO19749.1 - 0.00063 19.7 0.0 0.017 15.1 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Torsin PF06309.11 KLO19749.1 - 0.00095 19.3 0.0 0.94 9.6 0.0 2.9 2 0 0 2 2 2 2 Torsin APS_kinase PF01583.20 KLO19749.1 - 0.0013 18.6 0.2 1.1 9.2 0.1 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase RNA_helicase PF00910.22 KLO19749.1 - 0.0025 18.2 0.1 0.21 12.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 KLO19749.1 - 0.0028 17.6 0.0 0.0098 15.8 0.0 1.9 2 0 0 2 2 1 1 Rad17 P-loop domain AAA PF00004.29 KLO19749.1 - 0.0075 16.7 0.0 0.077 13.4 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KLO19749.1 - 0.039 13.4 0.0 0.46 9.9 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 KLO19749.1 - 0.04 13.6 0.0 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain TGT PF01702.18 KLO19749.1 - 0.06 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase AAA_33 PF13671.6 KLO19749.1 - 0.11 12.7 0.2 2.4 8.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain PSS PF03034.15 KLO19749.1 - 0.16 11.7 1.1 4.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Phosphatidyl serine synthase AAA_PrkA PF08298.11 KLO19749.1 - 0.19 10.6 0.0 0.69 8.8 0.0 1.8 2 0 0 2 2 2 0 PrkA AAA domain Abhydrolase_6 PF12697.7 KLO19751.1 - 2.1e-11 44.8 0.0 3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO19751.1 - 0.0037 16.5 0.0 0.0072 15.6 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Hydrophobin PF01185.18 KLO19752.1 - 5.8e-19 68.5 9.7 8e-19 68.1 9.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF3440 PF11922.8 KLO19754.1 - 0.027 14.2 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) DUF2436 PF10365.9 KLO19754.1 - 0.2 11.4 0.2 2 8.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2436) DUF4651 PF15513.6 KLO19758.1 - 0.092 12.6 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) His_Phos_2 PF00328.22 KLO19760.1 - 5.4e-85 286.0 0.0 7.3e-85 285.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KLO19760.1 - 1.7e-37 127.5 0.0 4.6e-37 126.0 0.0 1.8 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KLO19760.1 - 0.0015 18.2 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain YhdX PF17444.2 KLO19760.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized YhdX-like GCP_N_terminal PF17681.1 KLO19761.1 - 2.7e-97 326.1 0.0 6.9e-97 324.8 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KLO19761.1 - 7.2e-89 298.3 0.7 1.5e-88 297.3 0.3 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Mob1_phocein PF03637.17 KLO19762.1 - 1.5e-77 259.4 0.0 1.7e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family UPF0220 PF05255.11 KLO19763.1 - 8.2e-53 178.4 0.0 9.6e-53 178.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) GTP_EFTU PF00009.27 KLO19765.1 - 5.3e-42 143.6 0.0 1e-41 142.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KLO19765.1 - 5.6e-33 113.6 0.1 2e-32 111.8 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KLO19765.1 - 1.8e-10 41.1 1.1 4.7e-10 39.7 1.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KLO19765.1 - 0.0054 16.8 0.1 0.049 13.7 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ndc1_Nup PF09531.10 KLO19765.1 - 2.7 6.6 3.2 3.5 6.2 3.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SH3_9 PF14604.6 KLO19766.1 - 2.7e-40 136.0 9.5 6.7e-14 51.5 0.2 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.28 KLO19766.1 - 3.9e-40 135.2 7.4 2.5e-14 52.6 0.1 4.3 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 KLO19766.1 - 1.8e-29 101.3 0.0 3.6e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 KLO19766.1 - 2.3e-25 88.0 0.2 3.1e-07 30.0 0.0 4.7 4 0 0 4 4 4 4 Variant SH3 domain SH3_10 PF17902.1 KLO19766.1 - 9.7e-08 32.0 0.1 9.4e-05 22.4 0.0 3.6 2 1 1 3 3 3 1 SH3 domain SH3_3 PF08239.11 KLO19766.1 - 1.1e-07 32.0 5.8 0.0014 18.8 0.2 3.5 3 0 0 3 3 3 2 Bacterial SH3 domain SAM_4 PF18017.1 KLO19766.1 - 0.0046 16.9 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KLO19766.1 - 0.016 15.6 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) hSH3 PF14603.6 KLO19766.1 - 0.046 14.2 0.0 7 7.2 0.0 2.5 2 0 0 2 2 2 0 Helically-extended SH3 domain SH3_16 PF18348.1 KLO19766.1 - 2.6 7.9 4.1 13 5.6 0.1 3.1 3 0 0 3 3 3 0 Bacterial dipeptidyl-peptidase Sh3 domain DUF4778 PF16008.5 KLO19766.1 - 5.4 7.0 15.2 11 6.0 15.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Sec7 PF01369.20 KLO19767.1 - 8.7e-72 240.6 0.4 2.6e-71 239.1 0.4 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KLO19767.1 - 2.1e-46 157.7 3.6 2.1e-46 157.7 3.6 3.5 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KLO19767.1 - 1e-33 115.0 15.2 1.2e-33 114.8 0.3 6.0 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 KLO19767.1 - 2.7e-22 79.3 4.8 6.5e-20 71.5 0.6 4.3 4 0 0 4 4 4 2 Dimerisation and cyclophilin-binding domain of Mon2 DUF1539 PF07560.11 KLO19767.1 - 0.074 13.1 0.1 29 4.7 0.0 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) DS PF01916.17 KLO19768.1 - 5e-138 459.2 0.0 5.8e-138 459.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Sedlin_N PF04628.13 KLO19769.1 - 3.5e-17 62.8 0.0 4.1e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region NUDIX PF00293.28 KLO19770.1 - 7.2e-09 35.8 0.0 9.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain FA_desaturase PF00487.24 KLO19771.1 - 0.12 12.2 0.4 0.25 11.1 0.4 1.5 1 0 0 1 1 1 0 Fatty acid desaturase DUF3176 PF11374.8 KLO19771.1 - 1 9.6 5.9 0.14 12.3 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Nop PF01798.18 KLO19772.1 - 1.8e-85 286.1 0.1 3.4e-85 285.2 0.1 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KLO19772.1 - 6.3e-19 68.1 0.3 6.3e-19 68.1 0.3 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain adh_short PF00106.25 KLO19773.1 - 1.1e-08 34.8 0.1 0.00074 19.0 0.0 3.8 2 1 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 KLO19773.1 - 0.049 13.1 0.1 3.5 7.0 0.0 2.7 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Helitron_like_N PF14214.6 KLO19773.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus KR PF08659.10 KLO19773.1 - 0.096 12.6 0.5 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 KR domain adh_short_C2 PF13561.6 KLO19773.1 - 0.1 12.1 0.0 1.3 8.5 0.0 2.4 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Peptidase_M20 PF01546.28 KLO19774.1 - 2e-30 106.1 0.0 2.6e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KLO19774.1 - 0.00041 20.2 0.0 0.00071 19.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KLO19774.1 - 0.0023 17.6 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Shisa PF13908.6 KLO19775.1 - 0.025 14.9 0.0 0.28 11.4 0.0 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator CAP59_mtransfer PF11735.8 KLO19775.1 - 0.067 12.9 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Herpes_US9 PF06072.11 KLO19775.1 - 0.34 10.8 4.2 0.77 9.7 0.0 2.4 2 1 0 2 2 2 0 Alphaherpesvirus tegument protein US9 GFO_IDH_MocA PF01408.22 KLO19776.1 - 4e-20 72.8 0.6 6.4e-20 72.2 0.6 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KLO19776.1 - 0.0012 18.8 0.0 0.0042 17.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain MukB PF04310.12 KLO19776.1 - 0.0025 17.6 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 MukB N-terminal TrkA_N PF02254.18 KLO19776.1 - 0.049 13.9 0.1 0.088 13.1 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Sclerostin PF05463.11 KLO19776.1 - 0.059 13.1 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Sclerostin (SOST) HTH_20 PF12840.7 KLO19776.1 - 0.19 11.8 0.0 15 5.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain TFR_dimer PF04253.15 KLO19777.1 - 1.9e-20 73.1 0.4 5.9e-19 68.3 0.0 2.7 3 0 0 3 3 3 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KLO19777.1 - 3.2e-17 62.9 0.0 2.1e-16 60.2 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KLO19777.1 - 1.3e-12 47.5 0.2 3.4e-12 46.2 0.1 1.8 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 KLO19777.1 - 0.0049 16.4 0.2 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 Nicastrin Peptidase_M20 PF01546.28 KLO19777.1 - 0.033 13.9 0.0 0.088 12.5 0.0 1.9 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Mis14 PF08641.12 KLO19778.1 - 3.6e-08 33.8 9.3 3.6e-08 33.8 9.3 1.8 2 0 0 2 2 2 1 Kinetochore protein Mis14 like Iron_traffic PF04362.14 KLO19778.1 - 0.017 14.8 0.4 0.042 13.5 0.4 1.6 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking L_lactis_ph-MCP PF06673.11 KLO19778.1 - 0.029 13.4 1.1 0.041 12.9 1.1 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein DNTTIP1_dimer PF18192.1 KLO19778.1 - 0.28 11.6 3.3 0.82 10.1 0.1 2.9 3 1 1 4 4 4 0 DNTTIP1 dimerisation domain Microtub_bind PF13931.6 KLO19778.1 - 3.3 8.1 8.0 3 8.2 2.2 2.3 1 1 1 2 2 2 0 Kinesin-associated microtubule-binding F-box-like PF12937.7 KLO19779.1 - 7.7e-06 25.7 0.0 7.7e-06 25.7 0.0 2.6 3 0 0 3 3 3 1 F-box-like CDT1_C PF16679.5 KLO19780.1 - 3.9e-13 49.6 1.2 1.1e-12 48.2 0.2 2.3 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain ABC_tran_CTD PF16326.5 KLO19780.1 - 0.024 14.9 0.2 8.5 6.7 0.0 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain RCC1 PF00415.18 KLO19781.1 - 9.5e-68 224.7 6.9 2.4e-09 37.7 0.3 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KLO19781.1 - 7.5e-32 108.5 39.6 3.6e-06 26.6 0.4 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat MliC PF09864.9 KLO19781.1 - 0.0062 16.4 0.2 0.023 14.6 0.1 2.0 2 0 0 2 2 2 1 Membrane-bound lysozyme-inhibitor of c-type lysozyme DIOX_N PF14226.6 KLO19782.1 - 2.6e-26 92.7 0.1 4.4e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO19782.1 - 8.5e-17 61.5 0.0 1.5e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Alpha_kinase PF02816.18 KLO19783.1 - 5.4e-25 88.6 0.0 8.4e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family GPI-anchored PF10342.9 KLO19788.1 - 3.4e-09 37.4 1.4 3.4e-09 37.4 1.4 1.5 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PGAP1 PF07819.13 KLO19789.1 - 3.5e-56 190.5 0.0 4.8e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KLO19789.1 - 0.00013 22.6 0.0 0.00033 21.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO19789.1 - 0.0038 16.9 0.1 0.0086 15.8 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KLO19789.1 - 0.0051 16.1 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KLO19789.1 - 0.037 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 KLO19789.1 - 0.04 13.7 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KLO19789.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Snf7 PF03357.21 KLO19790.1 - 2.5e-44 150.9 15.5 3e-44 150.7 15.5 1.1 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KLO19790.1 - 0.00044 20.7 2.6 1.6 9.3 1.3 3.3 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 KLO19790.1 - 0.00077 17.1 11.1 0.00096 16.8 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Leu_zip PF15294.6 KLO19790.1 - 0.007 15.9 7.1 0.0091 15.5 7.1 1.3 1 0 0 1 1 1 1 Leucine zipper DUF3723 PF12520.8 KLO19790.1 - 0.011 14.5 3.3 0.012 14.4 2.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3723) DUF5344 PF17279.2 KLO19790.1 - 0.012 16.2 9.9 0.052 14.1 4.0 3.1 1 1 1 2 2 2 0 Family of unknown function (DUF5344) FlxA PF14282.6 KLO19790.1 - 0.013 15.5 11.4 0.013 15.5 11.4 2.3 1 1 1 2 2 2 0 FlxA-like protein PspA_IM30 PF04012.12 KLO19790.1 - 0.02 14.5 14.2 0.02 14.4 12.6 1.7 2 0 0 2 2 2 0 PspA/IM30 family NuA4 PF09340.10 KLO19790.1 - 0.023 14.6 3.3 0.044 13.7 1.7 2.3 1 1 1 2 2 2 0 Histone acetyltransferase subunit NuA4 Prominin PF05478.11 KLO19790.1 - 0.051 11.5 4.0 0.058 11.4 4.0 1.1 1 0 0 1 1 1 0 Prominin RE_Bsp6I PF09504.10 KLO19790.1 - 0.054 13.1 0.1 0.089 12.4 0.1 1.4 1 0 0 1 1 1 0 Bsp6I restriction endonuclease RPW8 PF05659.11 KLO19790.1 - 0.064 12.9 6.6 0.062 13.0 4.1 2.1 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FapA PF03961.13 KLO19790.1 - 0.081 11.5 9.2 0.028 13.0 5.1 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 KLO19790.1 - 0.081 13.1 5.6 0.74 10.0 4.7 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3091 PF11291.8 KLO19790.1 - 0.091 12.9 3.5 0.12 12.5 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3091) Prefoldin_2 PF01920.20 KLO19790.1 - 0.11 12.5 11.4 19 5.3 9.8 3.1 2 1 1 3 3 3 0 Prefoldin subunit Vps5 PF09325.10 KLO19790.1 - 0.16 11.5 9.7 0.21 11.1 8.8 1.6 1 1 0 1 1 1 0 Vps5 C terminal like FlaC_arch PF05377.11 KLO19790.1 - 0.23 11.9 5.9 4.7 7.7 0.0 3.6 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Metalloenzyme PF01676.18 KLO19790.1 - 0.39 10.0 1.6 0.92 8.8 1.5 1.8 1 1 0 1 1 1 0 Metalloenzyme superfamily GPS2_interact PF15784.5 KLO19790.1 - 0.45 11.0 5.2 0.23 11.9 2.0 2.2 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain bZIP_1 PF00170.21 KLO19790.1 - 0.62 10.2 8.4 6.3 7.0 0.0 3.2 2 1 0 2 2 2 0 bZIP transcription factor VPS11_C PF12451.8 KLO19790.1 - 1.3 9.3 0.1 1.3 9.3 0.1 2.8 2 1 1 3 3 3 0 Vacuolar protein sorting protein 11 C terminal YlqD PF11068.8 KLO19790.1 - 1.3 9.4 13.1 0.46 10.9 5.1 2.3 1 1 1 2 2 2 0 YlqD protein Uso1_p115_C PF04871.13 KLO19790.1 - 2 8.8 16.7 4.3 7.7 14.3 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Prefoldin PF02996.17 KLO19790.1 - 4.1 7.3 16.3 1.8 8.5 0.1 3.7 3 1 0 4 4 4 0 Prefoldin subunit APG6_N PF17675.1 KLO19790.1 - 5 7.6 17.7 6.9 7.2 6.1 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1644 PF07800.12 KLO19791.1 - 0.021 14.9 2.6 0.096 12.7 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) FOXP-CC PF16159.5 KLO19791.1 - 0.7 10.6 11.5 1.1 9.9 2.3 3.1 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-TRAF PF02176.18 KLO19791.1 - 1.5 9.5 8.0 8.8 7.1 1.5 2.6 3 0 0 3 3 3 0 TRAF-type zinc finger F-box-like PF12937.7 KLO19792.1 - 8.2e-09 35.2 0.0 3.9e-08 33.1 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO19792.1 - 0.024 14.5 0.8 5.3 7.0 0.2 3.0 2 0 0 2 2 2 0 F-box domain CTNNBL PF08216.11 KLO19793.1 - 8e-34 115.9 0.0 1.6e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KLO19793.1 - 0.034 14.2 0.1 2 8.6 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PPP1R26_N PF15740.5 KLO19793.1 - 0.058 12.0 0.9 0.078 11.6 0.9 1.2 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 26 N-terminus Amidohydro_2 PF04909.14 KLO19795.1 - 6.6e-24 85.2 0.0 1.1e-23 84.5 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KLO19795.1 - 0.0032 16.9 0.0 0.0088 15.4 0.0 1.7 2 1 0 2 2 2 1 TatD related DNase QRPTase_C PF01729.19 KLO19796.1 - 3.9e-50 169.9 0.1 5.2e-50 169.5 0.1 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KLO19796.1 - 1.3e-19 70.0 0.0 3.3e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain GMC_oxred_C PF05199.13 KLO19799.1 - 1e-14 55.3 0.0 2.3e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KLO19799.1 - 0.00021 20.8 0.0 0.0012 18.3 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase CAT_RBD PF03123.15 KLO19799.1 - 0.15 12.0 5.2 2.6 8.1 0.3 3.0 3 0 0 3 3 3 0 CAT RNA binding domain RRM_1 PF00076.22 KLO19800.1 - 4.6e-16 58.4 0.0 7.2e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Plasmodium_Vir PF05795.11 KLO19802.1 - 0.22 10.9 1.6 0.33 10.3 0.0 2.0 3 0 0 3 3 3 0 Plasmodium vivax Vir protein DUF1727 PF08353.10 KLO19804.1 - 0.094 12.6 0.1 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1727) Ifi-6-16 PF06140.13 KLO19805.1 - 9.1e-07 28.7 15.8 1.5e-06 28.1 15.8 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family Chloroplast_duf PF14476.6 KLO19805.1 - 0.026 13.5 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Petal formation-expressed Pkinase PF00069.25 KLO19806.1 - 7.7e-37 127.1 0.0 1.2e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19806.1 - 1.2e-36 126.3 0.0 1.7e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO19806.1 - 0.00028 20.9 0.0 0.0012 18.9 0.0 2.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO19806.1 - 0.00034 20.3 0.1 0.00081 19.0 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KLO19806.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OB_Dis3 PF17849.1 KLO19806.1 - 0.061 13.3 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Dis3-like cold-shock domain 2 (CSD2) Pkinase_Tyr PF07714.17 KLO19808.1 - 1.1e-35 123.2 0.0 1.5e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO19808.1 - 1.3e-30 106.7 0.0 1.8e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO19808.1 - 0.03 13.6 0.1 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 KLO19810.1 - 2.6e-42 144.9 0.0 3.6e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO19810.1 - 9.1e-40 136.7 0.0 1.2e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KLO19810.1 - 7.4e-07 28.8 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KLO19810.1 - 0.0064 15.3 0.0 0.0073 15.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTR1 PF03239.14 KLO19811.1 - 3.8e-59 200.4 3.9 4.8e-59 200.0 3.9 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3180 PF11377.8 KLO19811.1 - 0.038 14.1 1.2 0.038 14.1 1.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) DUF2852 PF11014.8 KLO19811.1 - 0.13 12.5 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Cation_efflux PF01545.21 KLO19811.1 - 8.9 6.0 16.8 0.33 10.6 1.4 3.2 3 0 0 3 3 3 0 Cation efflux family Ribosomal_L5e PF17144.4 KLO19812.1 - 8.2e-83 276.3 0.4 1.6e-82 275.4 0.4 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KLO19812.1 - 2.1e-35 121.5 6.3 2.1e-35 121.5 6.3 2.1 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 KLO19812.1 - 0.086 13.1 0.4 6.9 7.0 0.0 2.6 2 1 0 2 2 2 0 Threonine synthase N terminus MtrA PF04208.14 KLO19812.1 - 0.088 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A SAM_KSR1 PF13543.6 KLO19813.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 DEAD PF00270.29 KLO19814.1 - 8.5e-53 178.7 0.0 2.1e-51 174.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO19814.1 - 1.6e-26 92.8 0.0 6.2e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO19814.1 - 0.00034 20.7 0.0 0.0017 18.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Leu_zip PF15294.6 KLO19814.1 - 0.051 13.1 1.1 0.12 11.8 1.1 1.6 1 0 0 1 1 1 0 Leucine zipper CP12 PF02672.15 KLO19814.1 - 0.074 13.8 1.3 0.47 11.2 1.3 2.4 1 0 0 1 1 1 0 CP12 domain MFS_1 PF07690.16 KLO19815.1 - 3.2e-45 154.6 38.1 3.2e-45 154.6 38.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO19815.1 - 8.1e-11 41.4 22.9 1.2e-10 40.8 22.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 KLO19815.1 - 0.00049 18.6 8.8 0.00079 17.9 8.8 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Wzz PF02706.15 KLO19815.1 - 1.4 9.2 6.2 37 4.7 0.2 3.6 3 0 0 3 3 3 0 Chain length determinant protein MFS_4 PF06779.14 KLO19815.1 - 8.3 5.6 23.8 0.0099 15.2 7.1 3.0 3 0 0 3 3 3 0 Uncharacterised MFS-type transporter YbfB Nsp1_C PF05064.13 KLO19816.1 - 4e-30 104.0 0.3 2.1e-29 101.7 0.2 2.0 2 1 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KLO19816.1 - 1.8e-15 57.6 119.0 1.3e-05 25.9 41.7 5.7 1 1 4 5 5 5 5 Nucleoporin FG repeat region DUF3584 PF12128.8 KLO19816.1 - 0.003 15.2 2.0 0.0039 14.8 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 KLO19816.1 - 0.003 18.0 1.8 2.4 8.7 0.0 3.1 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.6 KLO19816.1 - 0.024 14.8 5.6 0.15 12.3 5.6 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Gene66 PF02053.15 KLO19816.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Gene 66 (IR5) protein Laminin_II PF06009.12 KLO19816.1 - 0.23 11.5 3.7 0.54 10.3 0.2 2.6 2 1 0 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.12 KLO19816.1 - 0.31 11.1 3.5 0.24 11.4 0.4 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HIP1_clath_bdg PF16515.5 KLO19816.1 - 0.39 11.4 3.9 6.5 7.4 0.4 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 KLO19816.1 - 1.9 8.6 4.3 0.67 10.0 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CorA PF01544.18 KLO19816.1 - 2.4 7.4 6.2 9.9 5.4 0.7 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Syntaxin-6_N PF09177.11 KLO19816.1 - 3 8.5 6.7 8.1 7.1 0.5 2.5 1 1 0 2 2 2 0 Syntaxin 6, N-terminal NAD_binding_6 PF08030.12 KLO19817.1 - 7.8e-19 68.3 0.0 1.3e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KLO19817.1 - 1.3e-15 57.4 0.0 2.3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KLO19817.1 - 2.5e-15 56.7 10.2 6.8e-15 55.3 10.2 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Aminotran_1_2 PF00155.21 KLO19818.1 - 5.7e-63 213.3 0.0 6.5e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KLO19818.1 - 0.00069 18.3 0.0 0.0019 16.8 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KLO19818.1 - 0.0012 17.8 0.0 0.08 11.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KLO19818.1 - 0.0061 15.9 0.0 0.0097 15.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KLO19818.1 - 0.025 13.9 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Sec63 PF02889.16 KLO19819.1 - 8.8e-72 241.3 0.0 1.5e-71 240.6 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KLO19819.1 - 2.3e-33 115.4 0.2 8.6e-27 94.0 0.4 4.3 4 1 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KLO19819.1 - 2.5e-11 43.9 0.0 7.2e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KLO19819.1 - 6.3e-07 29.7 0.1 0.0029 17.9 0.1 3.5 3 1 0 3 3 3 2 AAA domain Helicase_C PF00271.31 KLO19819.1 - 1.8e-06 28.2 0.0 2.8e-05 24.4 0.0 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain IstB_IS21 PF01695.17 KLO19819.1 - 0.0036 17.1 0.1 4.9 6.9 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_16 PF13191.6 KLO19819.1 - 0.0074 16.7 0.7 9.5 6.6 0.0 3.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 KLO19819.1 - 0.01 15.7 0.1 0.054 13.3 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 KLO19819.1 - 0.021 15.1 0.3 0.35 11.2 0.2 2.7 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KLO19819.1 - 0.036 13.8 0.0 0.4 10.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KLO19819.1 - 0.045 13.5 0.0 0.49 10.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KLO19819.1 - 0.067 13.7 2.4 0.84 10.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain EMC3_TMCO1 PF01956.16 KLO19820.1 - 4.3e-52 176.3 0.0 5.4e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like EF-hand_1 PF00036.32 KLO19821.1 - 1.4e-21 74.4 12.2 7.6e-07 28.2 0.1 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KLO19821.1 - 1.6e-20 73.3 8.2 2.7e-14 53.3 0.3 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KLO19821.1 - 5.8e-16 57.0 8.0 3e-05 23.6 0.9 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_4 PF12763.7 KLO19821.1 - 1.2e-08 34.8 9.1 0.0063 16.4 0.1 4.2 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 KLO19821.1 - 2.3e-07 30.5 13.1 0.00046 20.0 3.7 4.2 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KLO19821.1 - 1.1e-06 27.8 13.0 0.082 12.4 0.0 4.9 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.9 KLO19821.1 - 0.053 13.8 4.4 11 6.4 0.5 3.3 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region WD40 PF00400.32 KLO19823.1 - 0.0096 16.8 0.8 1.3 10.0 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF1513 PF07433.11 KLO19823.1 - 0.0098 15.0 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1513) ANAPC4_WD40 PF12894.7 KLO19823.1 - 0.013 15.8 0.0 1.2 9.5 0.0 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF5082 PF16888.5 KLO19824.1 - 0.018 15.3 0.2 0.065 13.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) F-box-like PF12937.7 KLO19825.1 - 0.0029 17.5 0.3 0.24 11.3 0.0 2.7 2 0 0 2 2 2 2 F-box-like TerB_N PF13208.6 KLO19825.1 - 0.14 11.9 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 TerB N-terminal domain ATE_C PF04377.15 KLO19826.1 - 8.7e-46 155.9 0.7 1.4e-45 155.2 0.7 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KLO19826.1 - 1.1e-27 96.2 4.4 2e-27 95.4 4.4 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DUF1129 PF06570.11 KLO19827.1 - 0.51 9.8 8.9 0.038 13.5 4.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) ODV-E18 PF10717.9 KLO19827.1 - 2.4 8.1 7.5 4.3 7.3 0.1 2.5 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF3021 PF11457.8 KLO19827.1 - 6.9 7.0 21.0 0.96 9.8 13.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) EF-hand_7 PF13499.6 KLO19828.1 - 1.5e-14 54.2 0.2 2.9e-08 34.0 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KLO19828.1 - 7.7e-14 50.1 2.6 1e-05 24.7 0.4 3.8 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KLO19828.1 - 4.6e-11 41.7 0.2 8.8e-05 22.1 0.1 3.8 4 1 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KLO19828.1 - 3.9e-10 38.8 1.5 2e-06 27.0 0.3 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KLO19828.1 - 2.5e-06 27.2 3.3 9.4e-05 22.2 0.1 3.2 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_4 PF12763.7 KLO19828.1 - 0.0013 18.7 0.3 0.093 12.7 0.0 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KLO19828.1 - 0.0038 17.5 0.1 0.95 9.8 0.1 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KLO19828.1 - 0.18 12.2 0.1 7.8 6.9 0.1 2.2 1 1 1 2 2 2 0 EF-hand domain ATE_C PF04377.15 KLO19830.1 - 2.5e-40 138.2 3.9 4.3e-40 137.4 3.9 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KLO19830.1 - 3.8e-24 84.9 4.0 7e-24 84.0 4.0 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Sugar_tr PF00083.24 KLO19831.1 - 3.9e-109 365.5 23.8 4.9e-109 365.2 23.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO19831.1 - 9.1e-22 77.4 39.9 1.2e-16 60.6 11.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KLO19831.1 - 1.8e-05 23.5 7.4 0.00018 20.2 2.2 3.2 4 0 0 4 4 4 2 MFS/sugar transport protein NYN PF01936.18 KLO19832.1 - 3.6e-17 63.2 0.0 9.9e-17 61.8 0.0 1.7 2 0 0 2 2 2 1 NYN domain IstB_IS21_ATP PF08483.11 KLO19832.1 - 0.00042 20.1 1.1 0.64 10.0 0.1 3.0 3 0 0 3 3 3 2 IstB-like ATP binding N-terminal Peptidase_S24 PF00717.23 KLO19833.1 - 9.2e-09 35.1 0.1 2.5e-08 33.8 0.1 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KLO19833.1 - 0.13 12.1 0.0 11 5.8 0.0 2.6 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 KCH PF16944.5 KLO19834.1 - 1.7e-91 306.5 15.1 2.1e-91 306.2 15.1 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF3810 PF12725.7 KLO19834.1 - 0.0099 15.3 2.4 0.023 14.0 2.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3810) DUF2593 PF10767.9 KLO19834.1 - 0.28 11.3 3.9 0.52 10.4 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2593) FAM163 PF15069.6 KLO19834.1 - 3 8.3 6.8 10 6.6 6.5 2.0 1 1 0 1 1 1 0 FAM163 family Nup88 PF10168.9 KLO19835.1 - 1.1e-29 102.9 0.0 6.5e-16 57.3 0.6 2.1 2 0 0 2 2 2 2 Nuclear pore component Nup54 PF13874.6 KLO19835.1 - 0.00042 20.4 7.6 0.00062 19.9 6.3 1.9 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 T7SS_ESX_EspC PF10824.8 KLO19835.1 - 0.028 14.9 0.0 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Bap31_Bap29_C PF18035.1 KLO19835.1 - 0.11 12.5 5.1 0.033 14.2 1.7 1.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Flg_bbr_C PF06429.13 KLO19835.1 - 0.17 12.0 0.1 0.92 9.7 0.0 2.1 2 0 0 2 2 2 0 Flagellar basal body rod FlgEFG protein C-terminal Proteasome PF00227.26 KLO19836.1 - 1.1e-45 155.5 0.0 1.3e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KLO19836.1 - 4.9e-13 48.5 0.1 9.5e-13 47.6 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribosomal_L27A PF00828.19 KLO19838.1 - 2.2e-34 118.9 0.2 3.4e-34 118.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SUR7 PF06687.12 KLO19839.1 - 5.7e-11 42.4 14.8 2.7e-09 37.0 14.8 2.1 1 1 0 1 1 1 1 SUR7/PalI family F-box-like PF12937.7 KLO19840.1 - 3.6e-08 33.2 0.9 3.6e-08 33.2 0.9 1.9 2 0 0 2 2 2 1 F-box-like PI31_Prot_C PF08577.11 KLO19841.1 - 8.5e-15 55.7 3.5 8.5e-15 55.7 3.5 3.3 3 1 0 3 3 3 1 PI31 proteasome regulator PI31_Prot_N PF11566.8 KLO19842.1 - 2.6e-33 115.1 0.0 4.3e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KLO19842.1 - 3.3e-14 53.8 16.1 3.3e-14 53.8 16.1 2.6 2 0 0 2 2 2 1 PI31 proteasome regulator Nop25 PF09805.9 KLO19843.1 - 1 9.8 9.1 0.1 13.1 2.7 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Ank_5 PF13857.6 KLO19844.1 - 3.3e-26 91.0 0.0 1.9e-09 37.6 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KLO19844.1 - 6.2e-25 87.2 0.5 5.9e-13 49.1 0.0 3.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KLO19844.1 - 3.3e-22 78.9 0.0 4e-14 53.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KLO19844.1 - 8.2e-20 68.8 0.0 8.5e-05 22.7 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat FYVE PF01363.21 KLO19844.1 - 3.6e-19 68.7 9.1 3.6e-19 68.7 9.1 2.5 3 0 0 3 3 2 1 FYVE zinc finger Ank PF00023.30 KLO19844.1 - 3.8e-15 55.6 0.4 0.0017 18.7 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat zf-RING_2 PF13639.6 KLO19844.1 - 3.8e-08 33.5 3.8 3.8e-08 33.5 3.8 3.9 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 KLO19844.1 - 1.9e-05 24.4 3.4 1.9e-05 24.4 3.4 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KLO19844.1 - 0.0028 17.9 4.0 0.0028 17.9 4.0 2.5 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KLO19844.1 - 0.004 16.9 4.7 0.004 16.9 4.7 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KLO19844.1 - 0.016 15.2 3.0 0.016 15.2 3.0 3.1 3 0 0 3 3 3 0 RING-type zinc-finger FYVE_2 PF02318.16 KLO19844.1 - 0.14 12.4 9.6 0.026 14.7 2.7 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger Inhibitor_I53 PF11714.8 KLO19844.1 - 0.18 12.0 0.4 0.46 10.7 0.4 1.6 1 0 0 1 1 1 0 Thrombin inhibitor Madanin HypA PF01155.19 KLO19844.1 - 0.35 10.9 4.7 1.3 9.1 1.4 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KLO19844.1 - 3.7 7.7 9.5 19 5.5 0.0 3.3 2 1 0 2 2 2 0 Zinc ribbon domain TrbL PF04610.14 KLO19845.1 - 4.2 7.1 8.2 0.61 9.8 0.7 2.4 2 1 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein BTB PF00651.31 KLO19846.1 - 3.5e-06 27.2 0.0 5.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PAP1 PF08601.10 KLO19846.1 - 2.9 7.5 4.7 4.5 6.9 4.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Methyltransf_25 PF13649.6 KLO19847.1 - 0.00057 20.5 0.0 0.031 15.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain BTB PF00651.31 KLO19848.1 - 3.3e-08 33.7 0.0 5.8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PRP38 PF03371.15 KLO19849.1 - 2.3e-62 210.0 1.0 2.8e-62 209.7 1.0 1.1 1 0 0 1 1 1 1 PRP38 family Ribonuc_red_sm PF00268.21 KLO19851.1 - 2.2e-123 411.2 1.2 2.7e-123 410.9 1.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 KLO19851.1 - 0.13 13.1 0.0 0.35 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) VMA21 PF09446.10 KLO19852.1 - 1.1e-10 41.5 7.5 1.8e-10 40.8 7.5 1.3 1 0 0 1 1 1 1 VMA21-like domain Phage_Orf51 PF06194.11 KLO19852.1 - 0.073 13.1 0.1 0.42 10.7 0.1 1.9 1 1 1 2 2 2 0 Phage Conserved Open Reading Frame 51 Alg6_Alg8 PF03155.15 KLO19853.1 - 1.6e-164 548.4 31.1 6.7e-163 543.1 31.1 2.0 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family MMR_HSR1_Xtn PF16897.5 KLO19854.1 - 1.6e-39 134.1 0.4 9.7e-39 131.7 0.4 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KLO19854.1 - 6.1e-23 80.6 0.1 1.1e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KLO19854.1 - 8.6e-21 74.2 0.0 2e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KLO19854.1 - 6e-09 35.6 0.2 1.7e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KLO19854.1 - 0.0087 15.1 0.5 0.031 13.3 0.1 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KLO19854.1 - 0.023 14.8 0.5 9.3 6.3 0.0 2.5 1 1 1 2 2 2 0 Dynamin family Pkinase PF00069.25 KLO19855.1 - 3.9e-39 134.6 0.0 1e-38 133.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19855.1 - 1.7e-38 132.4 0.0 7.8e-38 130.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO19855.1 - 1.1e-05 24.4 0.0 1.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO19855.1 - 0.00075 18.9 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KLO19855.1 - 0.0015 18.2 0.0 0.02 14.5 0.0 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KLO19855.1 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Proteasome PF00227.26 KLO19857.1 - 2.3e-46 157.7 0.2 2.6e-46 157.5 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit CSN8_PSD8_EIF3K PF10075.9 KLO19858.1 - 2.2e-26 92.6 0.1 3.2e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KLO19858.1 - 0.0031 17.0 0.0 0.0039 16.6 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family ECH_1 PF00378.20 KLO19859.1 - 1.8e-58 197.8 0.0 2.2e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KLO19859.1 - 6.4e-31 108.1 0.1 5e-28 98.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Sec10 PF07393.11 KLO19860.1 - 5.9e-225 748.9 7.7 7.2e-225 748.6 7.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Peptidase_S46 PF10459.9 KLO19860.1 - 0.0021 16.8 1.0 0.0021 16.8 1.0 2.0 2 0 0 2 2 2 1 Peptidase S46 COG2 PF06148.11 KLO19860.1 - 0.15 12.2 1.8 0.98 9.5 0.1 3.1 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RIX1 PF08167.12 KLO19861.1 - 2.4e-38 131.8 3.4 2.4e-38 131.8 3.4 2.0 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis RNA_pol_I_TF PF04090.12 KLO19862.1 - 3.4e-12 46.3 0.9 1.3e-08 34.6 0.1 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor TAF1_subA PF14929.6 KLO19862.1 - 0.016 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A Lipoprotein_20 PF13942.6 KLO19862.1 - 0.034 14.0 0.1 0.32 10.9 0.1 2.0 1 1 1 2 2 2 0 YfhG lipoprotein DUF5102 PF17104.5 KLO19863.1 - 1.2e-61 209.3 0.3 1.6e-61 208.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) FEZ PF07763.13 KLO19863.1 - 0.21 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 FEZ-like protein RNA_pol_Rpb1_5 PF04998.17 KLO19865.1 - 5.3e-88 294.9 0.0 1.1e-87 293.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KLO19865.1 - 2.7e-60 203.4 0.1 5.8e-60 202.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KLO19865.1 - 2.3e-34 118.6 0.0 6.8e-34 117.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KLO19865.1 - 6.2e-29 101.3 3.6 4.4e-22 78.8 0.1 3.8 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KLO19865.1 - 4e-23 81.4 0.0 1.2e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF4465 PF14717.6 KLO19865.1 - 0.16 12.3 0.0 0.39 11.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4465) F-box_5 PF18511.1 KLO19867.1 - 0.24 11.0 1.7 0.45 10.1 1.7 1.4 1 0 0 1 1 1 0 F-box MoeA_C PF03454.15 KLO19868.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) RRM_1 PF00076.22 KLO19869.1 - 1.6e-17 63.1 0.1 2.5e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KLO19869.1 - 3.6e-07 29.8 0.0 4.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 KLO19870.1 - 1.7e-42 145.2 0.2 3e-42 144.3 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO19870.1 - 6.5e-32 110.2 0.1 2.4e-31 108.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO19870.1 - 7.4e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KLO19870.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO19870.1 - 0.0021 18.4 1.2 0.075 13.4 0.4 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KLO19870.1 - 0.02 15.1 0.3 0.062 13.6 0.3 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KLO19870.1 - 0.068 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 KLO19870.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.25 KLO19870.1 - 0.14 11.4 0.1 0.34 10.2 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) DUF3449 PF11931.8 KLO19871.1 - 3e-73 245.5 0.3 3e-73 245.5 0.3 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KLO19871.1 - 2.5e-24 85.6 1.4 6e-24 84.4 1.4 1.7 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KLO19871.1 - 2.3e-11 43.4 1.5 4.8e-11 42.3 1.5 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KLO19871.1 - 2e-07 31.1 8.6 4.7e-07 30.0 2.9 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KLO19871.1 - 2.1e-07 31.0 1.4 2.1e-07 31.0 1.4 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KLO19871.1 - 0.00089 19.6 1.7 0.037 14.4 0.1 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 KLO19871.1 - 0.027 14.6 3.6 1.1 9.4 0.1 2.8 2 0 0 2 2 2 0 DBF zinc finger Matrilin_ccoil PF10393.9 KLO19871.1 - 0.11 12.3 0.6 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin zf-C2H2_4 PF13894.6 KLO19871.1 - 0.22 12.4 3.8 12 7.1 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DUF834 PF05754.14 KLO19871.1 - 0.26 11.3 3.6 0.1 12.6 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF834) Laps PF10169.9 KLO19871.1 - 6.3 7.4 14.0 0.45 11.1 0.2 3.9 5 0 0 5 5 5 0 Learning-associated protein Syja_N PF02383.18 KLO19872.1 - 5.8e-70 236.1 0.0 8.4e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain IMUP PF15761.5 KLO19872.1 - 0.16 12.7 0.1 0.32 11.7 0.1 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein F-box-like PF12937.7 KLO19873.1 - 0.064 13.2 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 F-box-like Abhydrolase_1 PF00561.20 KLO19874.1 - 3e-43 148.3 0.0 6.9e-43 147.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KLO19874.1 - 0.00024 20.8 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 KLO19874.1 - 0.0054 17.4 3.1 0.01 16.4 3.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO19874.1 - 0.091 12.0 0.1 2.8 7.1 0.1 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Snf7 PF03357.21 KLO19876.1 - 9.9e-08 31.8 18.2 1.4e-07 31.2 18.2 1.3 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 KLO19876.1 - 1.2e-05 25.3 6.3 1.8e-05 24.7 6.3 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway SlyX PF04102.12 KLO19876.1 - 0.027 15.1 12.9 0.3 11.7 1.6 3.9 3 2 1 4 4 4 0 SlyX HAP PF03866.13 KLO19876.1 - 0.029 14.4 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Hydrophobic abundant protein (HAP) DMSP_lyase PF16867.5 KLO19876.1 - 0.31 10.7 1.2 0.41 10.3 0.1 1.7 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase APC_N_CC PF16689.5 KLO19876.1 - 0.62 10.2 7.6 0.55 10.3 0.2 3.5 4 0 0 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain Erv26 PF04148.13 KLO19877.1 - 6e-65 218.9 6.1 7.9e-65 218.5 6.1 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF2909 PF11137.8 KLO19877.1 - 0.023 14.6 2.4 0.047 13.6 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) MnhB PF04039.13 KLO19877.1 - 0.073 13.4 3.3 1.2 9.4 1.3 2.2 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter BTB PF00651.31 KLO19879.1 - 0.018 15.2 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain 3A PF00803.18 KLO19880.1 - 0.063 12.6 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family CaMBD PF02888.16 KLO19882.1 - 0.19 11.9 0.4 5.5 7.3 0.0 2.9 4 0 0 4 4 4 0 Calmodulin binding domain Bac_luciferase PF00296.20 KLO19884.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Luciferase-like monooxygenase CorA PF01544.18 KLO19888.1 - 1.5e-45 155.7 0.1 2.1e-45 155.3 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 KLO19888.1 - 0.014 15.4 0.8 0.028 14.5 0.2 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PLU-1 PF08429.11 KLO19889.1 - 8.3e-55 186.3 6.6 2.1e-53 181.7 6.6 2.2 1 1 0 1 1 1 1 PLU-1-like protein JmjC PF02373.22 KLO19889.1 - 1.1e-40 138.6 0.5 2.9e-40 137.3 0.2 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 KLO19889.1 - 3.4e-16 59.7 0.0 1.8e-15 57.4 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KLO19889.1 - 8.7e-16 57.6 0.2 2e-15 56.4 0.2 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 KLO19889.1 - 5.9e-15 54.9 39.7 9.5e-13 47.8 3.7 4.5 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.16 KLO19889.1 - 4.2e-14 52.7 10.0 4.2e-14 52.7 10.0 2.8 2 0 0 2 2 2 1 C5HC2 zinc finger PHD_2 PF13831.6 KLO19889.1 - 2.9 7.5 28.1 1.8 8.2 0.6 3.8 4 0 0 4 4 4 0 PHD-finger Uds1 PF15456.6 KLO19890.1 - 3.2e-30 105.0 10.1 3.2e-30 105.0 10.1 5.3 3 2 2 5 5 5 1 Up-regulated During Septation KxDL PF10241.9 KLO19890.1 - 0.0065 16.7 3.2 0.0065 16.7 3.2 5.9 4 2 3 7 7 7 1 Uncharacterized conserved protein V-SNARE PF05008.15 KLO19890.1 - 0.023 15.1 0.5 0.023 15.1 0.5 6.7 4 3 3 8 8 8 0 Vesicle transport v-SNARE protein N-terminus DUF2163 PF09931.9 KLO19890.1 - 0.77 9.9 6.3 0.1 12.8 1.4 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2163) DNA_pol3_beta_2 PF02767.16 KLO19893.1 - 0.028 14.6 0.0 0.073 13.3 0.0 1.6 1 1 0 1 1 1 0 DNA polymerase III beta subunit, central domain VIR_N PF15912.5 KLO19894.1 - 1.7e-08 34.4 0.3 5.6e-08 32.7 0.3 1.8 1 1 0 1 1 1 1 Virilizer, N-terminal ORMDL PF04061.14 KLO19895.1 - 9.5e-48 161.5 1.2 1.3e-47 161.0 1.2 1.2 1 0 0 1 1 1 1 ORMDL family THF_DHG_CYH PF00763.23 KLO19896.1 - 9e-23 80.8 0.0 1.5e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KLO19896.1 - 1.3e-18 66.8 0.2 1.8e-08 33.8 0.0 2.8 2 2 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain OCD_Mu_crystall PF02423.15 KLO19896.1 - 0.0037 16.3 0.1 0.0055 15.7 0.1 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KLO19896.1 - 0.049 13.7 0.1 0.38 10.8 0.0 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase IPP-2 PF04979.14 KLO19897.1 - 3.7e-11 43.9 1.3 7.6e-11 42.9 1.3 1.5 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) RGM_C PF06534.13 KLO19897.1 - 0.075 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus AAA PF00004.29 KLO19898.1 - 8e-58 194.6 0.0 3.6e-40 137.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO19898.1 - 3.2e-11 43.7 0.3 0.00031 21.0 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KLO19898.1 - 8.4e-11 42.5 0.4 0.00031 21.2 0.2 3.3 2 1 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 KLO19898.1 - 5.1e-10 39.7 0.0 4.1e-06 27.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KLO19898.1 - 7.1e-09 35.8 0.1 0.0011 19.0 0.0 3.4 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KLO19898.1 - 4.7e-08 32.9 0.1 0.014 15.2 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KLO19898.1 - 9.9e-08 31.7 0.0 3.9e-07 29.8 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain Sigma54_activat PF00158.26 KLO19898.1 - 2.4e-07 30.6 0.1 0.024 14.3 0.0 3.6 3 0 0 3 3 3 2 Sigma-54 interaction domain TIP49 PF06068.13 KLO19898.1 - 2.5e-07 30.2 0.0 0.0057 15.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 KLO19898.1 - 2.9e-07 30.7 0.0 0.0086 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 KLO19898.1 - 6.9e-07 29.0 0.7 1.6e-05 24.6 0.1 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_24 PF13479.6 KLO19898.1 - 1.7e-06 27.9 0.1 0.028 14.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KLO19898.1 - 2.1e-06 28.0 0.0 0.064 13.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KLO19898.1 - 2.9e-06 27.9 0.0 0.029 14.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 KLO19898.1 - 3e-06 27.2 0.0 0.088 12.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KLO19898.1 - 3.7e-06 27.5 0.1 0.071 13.6 0.1 3.0 3 0 0 3 3 3 2 ABC transporter Mg_chelatase PF01078.21 KLO19898.1 - 6e-06 25.8 0.4 0.0071 15.8 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KLO19898.1 - 1.6e-05 24.7 0.1 0.11 12.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KLO19898.1 - 3.5e-05 23.4 0.1 0.033 13.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 KLO19898.1 - 3.6e-05 23.8 2.4 0.034 14.0 0.0 3.4 4 0 0 4 4 4 1 NACHT domain ATPase_2 PF01637.18 KLO19898.1 - 4.7e-05 23.4 0.2 3 7.7 0.0 4.1 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KLO19898.1 - 6.9e-05 22.9 0.0 0.39 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KLO19898.1 - 7.2e-05 22.2 0.4 0.003 16.9 0.1 2.4 2 0 0 2 2 2 1 KaiC AAA_30 PF13604.6 KLO19898.1 - 8.3e-05 22.4 0.0 0.46 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KLO19898.1 - 0.00029 20.5 2.5 2 7.9 0.0 4.2 4 0 0 4 4 4 1 AAA domain NB-ARC PF00931.22 KLO19898.1 - 0.00039 19.7 0.1 0.32 10.2 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_28 PF13521.6 KLO19898.1 - 0.00064 20.0 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 KLO19898.1 - 0.00095 18.3 0.0 0.85 8.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.16 KLO19898.1 - 0.0014 18.1 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 KLO19898.1 - 0.0015 18.4 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KLO19898.1 - 0.0073 16.1 0.0 0.48 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KLO19898.1 - 0.0077 15.3 0.0 3.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein CPT PF07931.12 KLO19898.1 - 0.0093 15.8 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 KLO19898.1 - 0.01 15.8 0.0 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TniB PF05621.11 KLO19898.1 - 0.012 15.0 0.0 9.1 5.6 0.0 3.0 2 1 0 2 2 2 0 Bacterial TniB protein Cytidylate_kin PF02224.18 KLO19898.1 - 0.014 15.1 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_19 PF13245.6 KLO19898.1 - 0.016 15.6 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KLO19898.1 - 0.016 14.9 0.2 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KLO19898.1 - 0.032 13.5 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 KLO19898.1 - 0.034 14.6 0.0 6.1 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KLO19898.1 - 0.035 13.3 0.1 4.2 6.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KLO19898.1 - 0.055 13.4 0.0 15 5.4 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain DUF2075 PF09848.9 KLO19898.1 - 0.063 12.5 0.0 3.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 KLO19898.1 - 0.066 12.4 0.0 24 4.0 0.0 3.1 3 0 0 3 3 3 0 KAP family P-loop domain IPT PF01745.16 KLO19898.1 - 0.079 12.3 0.1 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Sigma54_activ_2 PF14532.6 KLO19898.1 - 0.085 13.0 0.0 22 5.2 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 KLO19898.1 - 0.097 13.2 0.1 3.3 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 KLO19898.1 - 0.11 11.6 0.1 12 5.0 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2009 PF09418.10 KLO19899.1 - 2e-211 703.0 0.0 2.3e-211 702.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 KLO19899.1 - 1.9e-06 27.9 6.3 3.5e-06 27.1 6.3 1.5 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 KLO19899.1 - 0.00016 21.9 5.4 0.00039 20.6 5.4 1.6 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 KLO19899.1 - 0.3 11.3 4.8 0.78 10.0 4.8 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 KLO19899.1 - 0.34 10.8 5.4 0.69 9.8 5.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) STIMATE PF12400.8 KLO19900.1 - 8.7e-37 126.5 4.7 1.3e-36 125.9 4.7 1.3 1 0 0 1 1 1 1 STIMATE family Sec62 PF03839.16 KLO19900.1 - 0.0079 15.7 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Translocation protein Sec62 DUF1610 PF07754.11 KLO19902.1 - 0.051 13.6 2.8 1.3 9.1 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) XAF1_C PF18608.1 KLO19902.1 - 0.56 9.8 2.7 0.68 9.5 0.2 2.2 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain dsrm PF00035.26 KLO19903.1 - 3.1e-10 40.6 0.0 5.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribosomal_S5 PF00333.20 KLO19903.1 - 0.01 15.8 0.3 0.015 15.2 0.3 1.2 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain DUF3933 PF13069.6 KLO19903.1 - 0.048 13.5 1.1 0.091 12.6 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3933) PCI PF01399.27 KLO19907.1 - 6.4e-14 52.3 0.2 1.8e-13 50.9 0.1 1.8 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 KLO19907.1 - 1.4e-09 37.5 1.1 2.9e-09 36.5 1.1 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Pro-kuma_activ PF09286.11 KLO19908.1 - 8.2e-38 129.9 0.1 1.9e-37 128.7 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KLO19908.1 - 0.016 14.5 0.1 0.039 13.2 0.1 1.6 1 0 0 1 1 1 0 Subtilase family Pro-kuma_activ PF09286.11 KLO19909.1 - 5.9e-38 130.4 0.0 1.6e-37 129.0 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Hep_59 PF07052.11 KLO19910.1 - 4.4e-29 101.4 1.8 4.4e-29 101.4 1.8 2.3 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 CPP1-like PF11833.8 KLO19910.1 - 1 9.0 2.8 1.3 8.7 1.5 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like APOBEC4 PF18775.1 KLO19911.1 - 0.12 12.5 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 APOBEC4 AMPK1_CBM PF16561.5 KLO19913.1 - 0.13 12.4 0.0 0.47 10.7 0.0 2.0 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase DLIC PF05783.11 KLO19915.1 - 4.8e-46 157.6 9.0 1.8e-36 126.0 0.0 4.0 2 2 2 4 4 4 3 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 KLO19915.1 - 0.0021 18.5 0.1 0.016 15.6 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain Roc PF08477.13 KLO19915.1 - 0.003 17.7 0.0 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KLO19915.1 - 0.011 15.3 0.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 KLO19915.1 - 0.071 13.4 0.1 0.24 11.6 0.0 1.9 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KLO19915.1 - 0.075 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KLO19915.1 - 0.1 13.1 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KLO19915.1 - 0.11 12.3 0.1 0.22 11.3 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KLO19915.1 - 0.12 12.6 0.0 0.75 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KLO19915.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TIP41 PF04176.13 KLO19916.1 - 1.6e-62 210.1 0.0 1.9e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family RRM_1 PF00076.22 KLO19917.1 - 0.00035 20.3 0.0 0.00076 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KLO19917.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_1 PF00076.22 KLO19918.1 - 0.18 11.7 0.2 11 6.0 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Casein PF00363.18 KLO19920.1 - 0.0037 17.6 0.2 0.0047 17.3 0.2 1.2 1 0 0 1 1 1 1 Casein F-box-like PF12937.7 KLO19922.1 - 2.8e-05 23.9 4.7 0.0001 22.1 2.5 2.7 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 KLO19923.1 - 6.7e-06 25.9 0.9 7.4e-05 22.6 0.1 2.5 2 0 0 2 2 2 1 F-box-like Tetraspanin PF00335.20 KLO19924.1 - 0.43 10.3 2.0 0.41 10.3 0.2 1.7 2 0 0 2 2 2 0 Tetraspanin family MPDZ_u10 PF16667.5 KLO19924.1 - 0.45 11.4 3.3 1.4 9.8 3.3 1.9 1 0 0 1 1 1 0 Unstructured region 10 on multiple PDZ protein Abhydrolase_1 PF00561.20 KLO19926.1 - 1.8e-28 99.9 0.3 9.6e-23 81.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO19926.1 - 2.6e-16 60.9 0.1 4.5e-16 60.1 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO19926.1 - 2.5e-10 40.0 0.0 2.5e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KLO19926.1 - 1.6e-07 30.3 0.0 3.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 KLO19926.1 - 0.0012 18.9 0.0 0.0021 18.2 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.18 KLO19926.1 - 0.0035 16.9 0.0 4.8 6.7 0.0 3.0 2 1 0 2 2 2 2 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 KLO19926.1 - 0.12 10.9 0.0 0.38 9.2 0.0 1.7 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Btz PF09405.10 KLO19927.1 - 2.8e-08 34.1 7.6 2.8e-08 34.1 7.6 2.4 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding TFIIB PF00382.19 KLO19928.1 - 3.8e-34 116.6 0.1 2.7e-21 75.4 0.1 2.9 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KLO19928.1 - 1.7e-12 46.6 1.2 2.7e-12 46.0 1.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Guanylin PF02058.15 KLO19928.1 - 3.7e-05 24.1 0.6 0.14 12.6 0.0 3.0 2 1 1 3 3 3 3 Guanylin precursor RB_B PF01857.20 KLO19928.1 - 0.008 16.2 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 KLO19928.1 - 0.028 14.1 0.2 0.048 13.4 0.2 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Cyclin_C PF02984.19 KLO19928.1 - 0.035 14.2 0.0 0.76 9.9 0.1 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain DUF5029 PF16432.5 KLO19928.1 - 0.037 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5029) Sigma70_r4 PF04545.16 KLO19928.1 - 0.053 13.1 0.0 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_28 PF13518.6 KLO19928.1 - 0.18 11.9 0.5 25 5.1 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain zf-ribbon_3 PF13248.6 KLO19928.1 - 0.52 9.8 2.8 0.78 9.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RRS1 PF04939.12 KLO19929.1 - 1.7e-58 197.1 8.0 3.1e-58 196.2 8.0 1.4 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Pigment_DH PF06324.11 KLO19929.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) SMK-1 PF04802.15 KLO19930.1 - 1.6e-78 263.0 0.6 2.7e-78 262.2 0.6 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 PBP1_TM PF14812.6 KLO19930.1 - 0.053 13.9 4.5 0.97 9.9 0.1 3.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VID27_N PF17748.1 KLO19930.1 - 0.1 12.5 0.3 13 5.6 0.0 2.7 2 0 0 2 2 2 0 VID27 N-terminal region YozE_SAM_like PF06855.12 KLO19930.1 - 0.1 12.8 0.1 13 6.0 0.0 2.6 2 0 0 2 2 2 0 YozE SAM-like fold CENP-B_dimeris PF09026.10 KLO19930.1 - 0.33 11.4 0.1 0.33 11.4 0.1 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Abhydrolase_2 PF02230.16 KLO19931.1 - 5e-57 193.2 0.0 3.8e-56 190.3 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KLO19931.1 - 0.00015 21.1 0.2 0.59 9.3 0.1 3.2 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KLO19931.1 - 0.0011 19.6 0.0 0.0029 18.2 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KLO19931.1 - 0.0043 16.7 0.4 2.9 7.5 0.1 3.0 2 1 1 3 3 3 1 alpha/beta hydrolase fold FSH1 PF03959.13 KLO19931.1 - 0.005 16.5 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 KLO19931.1 - 0.023 14.4 0.0 0.028 14.1 0.0 1.3 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KLO19931.1 - 0.054 13.4 0.0 0.094 12.6 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KLO19931.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) tRNA_m1G_MT PF01746.21 KLO19932.1 - 5.5e-29 101.3 0.3 1.1e-28 100.3 0.3 1.5 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase NARP1 PF12569.8 KLO19932.1 - 0.057 12.3 10.9 0.098 11.5 10.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RPN2_C PF18004.1 KLO19932.1 - 9.9 6.1 15.0 3.3 7.6 11.3 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Methyltransf_23 PF13489.6 KLO19933.1 - 3.4e-14 53.0 0.0 4.8e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO19933.1 - 2.5e-10 41.0 0.0 5.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO19933.1 - 6.1e-10 39.6 0.0 1.1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO19933.1 - 9.4e-09 35.9 0.0 1.7e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO19933.1 - 9.4e-06 25.5 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KLO19933.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KLO19933.1 - 0.0054 15.9 0.0 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 KLO19933.1 - 0.088 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KLO19933.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase zf-C2H2 PF00096.26 KLO19934.1 - 5.6 7.6 12.7 1.4 9.5 1.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 KLO19934.1 - 6.9 7.4 10.2 55 4.5 7.3 3.2 2 1 0 2 2 2 0 FOXP coiled-coil domain CxC6 PF18721.1 KLO19934.1 - 7.9 6.8 6.9 5.6 7.3 3.3 2.2 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases RNA_pol_Rpb2_6 PF00562.28 KLO19936.1 - 1.1e-110 370.4 0.0 1.9e-110 369.6 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KLO19936.1 - 4.9e-30 104.6 0.0 8.2e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KLO19936.1 - 2.1e-28 98.3 0.0 4.6e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 KLO19936.1 - 3.7e-23 81.3 0.0 9.8e-23 79.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KLO19936.1 - 5.6e-20 71.8 0.0 1e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KLO19936.1 - 5.8e-19 68.3 0.1 3.9e-15 56.0 0.3 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 UCH PF00443.29 KLO19937.1 - 5.3e-50 170.3 0.1 7.8e-50 169.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KLO19937.1 - 1.5e-20 74.1 0.0 5.3e-20 72.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-H2C2_2 PF13465.6 KLO19938.1 - 7.6e-13 48.3 24.6 2.1e-08 34.2 0.6 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 KLO19938.1 - 1.3e-07 31.7 29.5 0.00014 22.1 0.3 4.9 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO19938.1 - 2.1e-07 31.2 22.2 0.21 12.5 0.4 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KLO19938.1 - 0.0023 18.1 6.4 0.2 11.8 0.3 2.2 1 1 1 2 2 2 2 Aberrant zinc-finger FOXP-CC PF16159.5 KLO19938.1 - 0.029 15.0 3.9 0.5 11.0 0.1 2.6 2 1 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KLO19938.1 - 0.032 14.0 0.2 0.032 14.0 0.2 4.7 6 0 0 6 6 5 0 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 KLO19938.1 - 0.038 14.7 1.3 0.038 14.7 1.3 2.3 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 KLO19938.1 - 0.066 13.5 7.6 0.031 14.6 4.2 2.3 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-B_box PF00643.24 KLO19938.1 - 0.32 11.2 6.2 0.14 12.3 2.6 2.2 2 0 0 2 2 2 0 B-box zinc finger zf-C2HC_2 PF13913.6 KLO19938.1 - 2.2 8.3 7.4 3.5 7.6 0.1 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type C1_4 PF07975.12 KLO19938.1 - 3.6 7.9 12.5 1.7 8.9 4.5 3.1 1 1 2 3 3 3 0 TFIIH C1-like domain zf-met PF12874.7 KLO19938.1 - 4.6 7.8 20.2 0.58 10.6 0.8 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type F-box PF00646.33 KLO19939.1 - 1.9e-05 24.4 2.1 1.9e-05 24.4 2.1 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KLO19939.1 - 0.00021 21.1 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KLO19939.1 - 0.00076 19.3 0.5 0.0024 17.7 0.5 1.9 1 0 0 1 1 1 1 F-box-like LNS2 PF08235.13 KLO19940.1 - 6.9e-101 336.4 0.0 9.1e-101 336.1 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KLO19940.1 - 9.3e-37 125.1 0.0 2.3e-36 123.9 0.0 1.7 2 0 0 2 2 2 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KLO19940.1 - 1e-14 54.5 0.0 1.9e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Acid_phosphat_B PF03767.14 KLO19940.1 - 0.078 12.5 0.1 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF4666 PF15697.5 KLO19940.1 - 0.48 11.1 5.0 3.7 8.3 1.4 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4666) DUF3827 PF12877.7 KLO19940.1 - 7 4.9 6.0 13 4.0 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) PP2C PF00481.21 KLO19941.1 - 1.3e-24 87.3 0.0 4.5e-23 82.2 0.0 2.7 2 1 0 2 2 2 1 Protein phosphatase 2C Na_H_Exchanger PF00999.21 KLO19943.1 - 1.6e-53 181.9 50.8 2.3e-53 181.3 50.8 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family His_biosynth PF00977.21 KLO19944.1 - 2.3e-35 122.1 0.0 3.1e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein TB2_DP1_HVA22 PF03134.19 KLO19945.1 - 6.1e-09 35.7 0.3 1.3e-08 34.7 0.2 1.6 1 1 0 1 1 1 1 TB2/DP1, HVA22 family Fe-ADH PF00465.19 KLO19947.1 - 1.8e-89 300.1 0.0 2.4e-89 299.7 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KLO19947.1 - 6.7e-11 42.4 0.0 4.3e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Acetyltransf_8 PF13523.6 KLO19948.1 - 2.8e-32 111.4 0.7 4.1e-32 110.9 0.7 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KLO19948.1 - 0.008 16.8 0.1 0.016 15.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain F-box-like PF12937.7 KLO19949.1 - 0.00015 21.5 0.1 0.00037 20.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO19950.1 - 4.6e-06 26.4 0.8 2.9e-05 23.9 0.2 2.7 2 0 0 2 2 2 1 F-box-like Polysacc_deac_1 PF01522.21 KLO19951.1 - 1.4e-24 86.4 0.1 1.1e-23 83.5 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase Collagen_bind PF05737.12 KLO19951.1 - 1.5 9.0 6.5 0.54 10.4 3.4 1.8 3 0 0 3 3 3 0 Collagen binding domain F-box-like PF12937.7 KLO19953.1 - 0.00026 20.8 0.4 0.00026 20.8 0.4 2.1 2 0 0 2 2 2 1 F-box-like LSM PF01423.22 KLO19954.1 - 5.7e-13 48.4 0.0 7.3e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain PhnA PF03831.14 KLO19954.1 - 0.013 15.3 0.1 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 PhnA domain Hfq PF17209.3 KLO19954.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Hfq protein DUF810 PF05664.11 KLO19955.1 - 0.11 11.0 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Plant family of unknown function (DUF810) Ribophorin_I PF04597.14 KLO19956.1 - 4.7e-132 441.3 0.6 5.3e-132 441.1 0.6 1.0 1 0 0 1 1 1 1 Ribophorin I DUF378 PF04070.12 KLO19957.1 - 0.037 13.9 0.5 0.056 13.3 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF378) PPR_2 PF13041.6 KLO19958.1 - 4.8e-14 52.3 10.7 9.7e-10 38.5 0.3 5.5 6 0 0 6 6 6 2 PPR repeat family PPR PF01535.20 KLO19958.1 - 4.2e-09 36.0 9.7 0.43 10.9 0.0 7.4 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 KLO19958.1 - 4.9e-09 36.1 0.1 2.2e-06 27.6 0.1 3.7 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 KLO19958.1 - 0.0008 19.1 5.1 0.37 10.5 0.0 5.2 6 0 0 6 6 6 1 PPR repeat PPR_long PF17177.4 KLO19958.1 - 0.035 13.5 0.7 1.4 8.3 0.0 3.3 3 1 1 4 4 4 0 Pentacotripeptide-repeat region of PRORP Asp PF00026.23 KLO19959.1 - 4.5e-32 111.7 0.4 1.2e-26 93.9 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Protocadherin PF08374.11 KLO19959.1 - 0.00086 19.3 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Protocadherin Asp_protease_2 PF13650.6 KLO19959.1 - 0.0027 18.3 0.1 0.67 10.6 0.0 3.2 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.6 KLO19959.1 - 0.0094 16.2 1.0 1.6 9.0 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal ECSCR PF15820.5 KLO19959.1 - 0.082 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Adeno_E3_CR2 PF02439.15 KLO19959.1 - 0.23 11.2 2.1 0.49 10.2 2.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 F-box-like PF12937.7 KLO19960.1 - 2e-05 24.4 0.4 0.00012 21.9 0.4 2.2 1 1 0 1 1 1 1 F-box-like Minor_capsid_3 PF12691.7 KLO19960.1 - 0.037 14.4 0.0 0.081 13.3 0.0 1.5 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage LRR_4 PF12799.7 KLO19960.1 - 0.24 11.9 10.2 1 9.9 0.1 4.9 1 1 5 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KLO19960.1 - 0.4 11.4 2.9 2.2e+02 3.1 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat F-box-like PF12937.7 KLO19961.1 - 0.00037 20.3 0.3 0.0011 18.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KLO19962.1 - 1.1e-05 25.3 0.2 3.9e-05 23.5 0.2 2.1 1 1 0 1 1 1 1 F-box-like DNA_pol_B_3 PF08408.10 KLO19962.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase family B viral insert F-box-like PF12937.7 KLO19963.1 - 0.00037 20.3 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like peroxidase PF00141.23 KLO19965.1 - 1.2e-27 97.1 0.0 2.4e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KLO19965.1 - 2.4e-27 94.6 2.2 5.9e-27 93.4 2.2 1.7 1 0 0 1 1 1 1 Fungal peroxidase extension region Pkinase PF00069.25 KLO19966.1 - 1.7e-67 227.5 0.0 2.4e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19966.1 - 1.7e-43 148.8 0.0 2.5e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO19966.1 - 6.6e-06 25.2 0.3 1.4e-05 24.1 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KLO19966.1 - 0.0039 17.2 0.0 0.54 10.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO19966.1 - 0.024 14.0 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like zf-C2H2 PF00096.26 KLO19967.1 - 1.8e-08 34.4 6.3 0.00062 20.1 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KLO19967.1 - 0.00018 21.8 0.7 0.00018 21.8 0.7 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KLO19967.1 - 0.0025 18.5 8.4 0.22 12.5 0.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KLO19967.1 - 0.0052 16.5 0.6 0.33 10.8 0.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-MYST PF17772.1 KLO19967.1 - 0.17 11.5 0.6 0.37 10.4 0.3 1.7 1 1 0 1 1 1 0 MYST family zinc finger domain zf-C2H2_jaz PF12171.8 KLO19967.1 - 0.45 10.9 1.3 4 7.8 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TFIIF_alpha PF05793.12 KLO19969.1 - 9.1e-13 47.6 71.2 1.5e-08 33.7 50.7 5.2 2 2 2 4 4 4 3 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 KLO19969.1 - 1.7 6.8 25.1 2.7 6.1 25.1 1.2 1 0 0 1 1 1 0 Nop14-like family Peroxidase_ext PF11895.8 KLO19970.1 - 2.6e-27 94.5 2.1 6.3e-27 93.3 2.1 1.7 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 KLO19970.1 - 3.5e-17 62.9 0.1 8.2e-17 61.7 0.0 1.6 2 0 0 2 2 2 1 Peroxidase Ysc84 PF04366.12 KLO19971.1 - 2.9e-37 127.3 0.1 4.3e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KLO19971.1 - 1.2e-15 56.8 0.1 2.9e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KLO19971.1 - 5e-13 48.7 0.0 1.1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KLO19971.1 - 6.4e-11 41.8 0.1 2.4e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain PIF1 PF05970.14 KLO19972.1 - 1.8e-57 195.2 0.3 6.7e-55 186.7 0.3 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KLO19972.1 - 1.1e-17 64.4 0.0 4.1e-17 62.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KLO19972.1 - 1.7e-07 31.7 0.0 8.8e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 KLO19972.1 - 8.3e-07 27.3 0.2 0.00092 17.3 0.0 2.2 2 0 0 2 2 2 2 Helicase AAA_16 PF13191.6 KLO19972.1 - 3.9e-05 24.1 0.3 0.0001 22.7 0.3 1.6 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 KLO19972.1 - 5.5e-05 22.9 0.1 0.00013 21.7 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain SH3_13 PF18335.1 KLO19972.1 - 0.00037 20.3 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain AAA_22 PF13401.6 KLO19972.1 - 0.0041 17.4 0.1 0.017 15.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KLO19972.1 - 0.0044 16.8 0.6 0.43 10.3 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KLO19972.1 - 0.019 14.5 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KLO19972.1 - 0.021 14.2 0.1 0.04 13.3 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KLO19972.1 - 0.022 14.2 0.0 0.086 12.3 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 KLO19972.1 - 0.037 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KLO19972.1 - 0.042 13.9 0.8 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KLO19972.1 - 0.056 13.3 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 KLO19972.1 - 0.065 13.2 0.2 0.42 10.6 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KLO19972.1 - 0.072 13.6 0.2 0.16 12.4 0.2 1.7 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KLO19972.1 - 0.073 13.0 0.2 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KLO19972.1 - 0.085 12.8 0.6 0.31 10.9 0.2 2.2 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 KLO19972.1 - 0.094 12.5 0.1 3.9 7.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KLO19972.1 - 0.095 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KLO19972.1 - 0.1 11.8 0.0 0.63 9.2 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 KLO19972.1 - 0.21 10.8 2.4 0.46 9.7 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RhoGAP PF00620.27 KLO19973.1 - 1.2e-36 125.8 0.0 3e-36 124.5 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KLO19973.1 - 2.2e-09 37.5 1.7 2.2e-09 37.5 1.7 2.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain TEX12 PF15219.6 KLO19973.1 - 0.0089 16.3 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 Testis-expressed 12 DUF5344 PF17279.2 KLO19973.1 - 0.035 14.7 0.2 13 6.4 0.1 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5344) MRP-63 PF14978.6 KLO19973.1 - 0.14 12.8 1.5 46 4.7 0.1 3.4 3 0 0 3 3 3 0 Mitochondrial ribosome protein 63 ABC_membrane PF00664.23 KLO19974.1 - 6.4e-49 167.0 26.7 5.5e-27 95.1 2.5 4.7 4 1 1 5 5 5 3 ABC transporter transmembrane region ABC_tran PF00005.27 KLO19974.1 - 2.4e-44 151.2 0.0 1e-25 90.8 0.0 3.4 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KLO19974.1 - 1.1e-11 44.6 0.0 0.00059 19.3 0.0 4.1 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KLO19974.1 - 5.9e-06 26.8 0.2 0.083 13.3 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KLO19974.1 - 3.8e-05 24.3 2.3 0.00074 20.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KLO19974.1 - 4.2e-05 23.2 0.7 0.064 13.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KLO19974.1 - 4.6e-05 23.4 5.2 0.0077 16.1 0.4 4.2 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KLO19974.1 - 0.00023 20.8 0.0 0.35 10.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 KLO19974.1 - 0.0006 20.0 0.1 0.097 12.8 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 KLO19974.1 - 0.00065 18.8 0.0 0.056 12.5 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KLO19974.1 - 0.00078 19.5 0.3 0.64 10.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KLO19974.1 - 0.0012 18.6 0.1 0.021 14.5 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KLO19974.1 - 0.0032 17.4 0.2 2.2 8.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 KLO19974.1 - 0.0045 16.4 0.1 2.2 7.6 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family IstB_IS21 PF01695.17 KLO19974.1 - 0.0047 16.7 0.1 4.8 6.9 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 KLO19974.1 - 0.0051 17.1 0.4 2.8 8.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KLO19974.1 - 0.0052 16.3 0.0 2.5 7.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region aGPT-Pplase1 PF18723.1 KLO19974.1 - 0.0059 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 AAA_5 PF07728.14 KLO19974.1 - 0.011 15.7 0.1 8.4 6.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 KLO19974.1 - 0.048 13.7 1.5 3.4 7.7 0.1 2.6 2 0 0 2 2 2 0 Dynamin family Adeno_IVa2 PF02456.15 KLO19974.1 - 0.053 12.3 1.1 0.45 9.3 0.0 2.4 3 0 0 3 3 3 0 Adenovirus IVa2 protein ATPase_2 PF01637.18 KLO19974.1 - 0.066 13.1 0.0 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 KLO19974.1 - 0.082 12.3 1.1 8.9 5.7 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_11 PF13086.6 KLO19974.1 - 0.096 12.5 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KLO19974.1 - 0.098 13.1 0.4 2.7 8.4 0.0 3.2 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KLO19974.1 - 0.098 13.2 0.0 15 6.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KLO19974.1 - 0.26 11.7 0.9 39 4.7 0.0 3.1 3 0 0 3 3 2 0 RNA helicase cobW PF02492.19 KLO19974.1 - 0.87 9.1 2.6 2.7 7.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RRM_1 PF00076.22 KLO19975.1 - 1e-14 54.1 0.1 1.5e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KLO19975.1 - 7.5e-08 32.1 1.8 1.3e-07 31.3 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KLO19975.1 - 0.00082 19.3 0.5 0.0019 18.1 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KLO19975.1 - 0.0021 17.7 1.2 0.0076 15.9 1.2 2.0 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KLO19975.1 - 0.17 11.6 1.8 0.18 11.5 0.2 1.8 2 0 0 2 2 2 0 Zinc knuckle RRM_7 PF16367.5 KLO19975.1 - 0.2 11.8 0.0 0.48 10.6 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif zf-CCHC_6 PF15288.6 KLO19975.1 - 0.36 10.7 5.2 0.96 9.3 5.2 1.7 1 0 0 1 1 1 0 Zinc knuckle Glyco_hydro_72 PF03198.14 KLO19976.1 - 1.3e-88 297.3 0.2 2e-88 296.7 0.0 1.3 2 0 0 2 2 2 1 Glucanosyltransferase X8 PF07983.13 KLO19976.1 - 1.3e-19 70.7 0.6 3.4e-19 69.3 0.6 1.8 1 0 0 1 1 1 1 X8 domain Herpes_capsid PF06112.11 KLO19976.1 - 0.0089 16.1 10.6 0.0089 16.1 10.6 2.8 2 1 1 3 3 3 1 Gammaherpesvirus capsid protein SUR7 PF06687.12 KLO19977.1 - 4.3e-16 59.2 3.8 4.3e-16 59.2 3.8 2.1 1 1 1 2 2 2 2 SUR7/PalI family Claudin_2 PF13903.6 KLO19977.1 - 0.0043 16.8 2.6 0.0043 16.8 2.6 1.7 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Glyco_transf_28 PF03033.20 KLO19978.1 - 1.2e-31 109.6 0.0 3.5e-31 108.1 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 KLO19978.1 - 2.2e-25 88.8 3.1 1.7e-15 56.9 0.2 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.29 KLO19978.1 - 5.6e-14 52.5 0.7 1.5e-12 47.9 0.5 2.6 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 KLO19978.1 - 8.5e-07 28.1 0.0 2.6e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 KLO19978.1 - 5.1e-05 23.7 3.7 0.014 15.8 3.7 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KLO19978.1 - 8.4e-05 22.8 0.2 0.00021 21.5 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KLO19978.1 - 0.0014 18.7 0.2 0.003 17.6 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 KLO19978.1 - 0.0018 18.5 0.0 0.0056 16.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KLO19978.1 - 0.053 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_13 PF16652.5 KLO19978.1 - 0.089 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain DIOX_N PF14226.6 KLO19979.1 - 1.7e-08 35.2 0.0 4.1e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO19979.1 - 0.0033 17.9 0.0 0.015 15.8 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KLO19980.1 - 1.5e-63 214.7 0.0 3e-63 213.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19980.1 - 2e-34 119.1 0.1 3.3e-26 92.1 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KLO19980.1 - 0.00016 21.7 1.2 0.00056 19.9 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO19980.1 - 0.00023 20.6 0.4 0.0036 16.7 0.1 2.4 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KLO19980.1 - 0.0076 15.3 0.2 0.024 13.7 0.0 1.8 2 0 0 2 2 2 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KLO19980.1 - 0.018 13.8 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KLO19980.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 adh_short PF00106.25 KLO19981.1 - 2.2e-25 89.3 0.1 2.9e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO19981.1 - 8.7e-24 84.4 0.0 1e-23 84.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO19981.1 - 3.4e-06 27.1 0.1 4.7e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO19981.1 - 9.5e-05 22.0 0.0 0.00023 20.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KLO19981.1 - 0.0051 16.7 0.1 0.0093 15.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KLO19981.1 - 0.14 11.6 0.2 4.6 6.5 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase MMR_HSR1_Xtn PF16897.5 KLO19982.1 - 8.8e-41 138.2 1.7 2e-40 137.1 1.7 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KLO19982.1 - 3.6e-21 75.0 0.0 6e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KLO19982.1 - 4.1e-19 68.7 0.0 1e-18 67.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KLO19982.1 - 2.8e-10 39.9 0.0 5.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KLO19982.1 - 0.00033 20.8 0.1 0.12 12.4 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Lactamase_B_2 PF12706.7 KLO19983.1 - 3.1e-23 82.4 0.0 2.1e-21 76.4 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KLO19983.1 - 0.00013 22.0 0.1 0.0003 20.9 0.1 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 KLO19983.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KLO19983.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain PRELI PF04707.14 KLO19984.1 - 2e-32 112.2 0.0 2.6e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family RIC1 PF07064.13 KLO19985.1 - 2.7e-92 308.8 1.3 3.8e-92 308.2 1.3 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 KLO19985.1 - 0.0011 19.3 0.2 0.51 10.7 0.0 4.2 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain FAM176 PF14851.6 KLO19986.1 - 0.0011 18.6 3.8 0.079 12.6 4.8 2.6 2 0 0 2 2 2 1 FAM176 family Myc_N PF01056.18 KLO19986.1 - 0.0042 17.0 5.4 0.0042 17.0 5.4 1.6 2 0 0 2 2 2 1 Myc amino-terminal region Cwf_Cwc_15 PF04889.12 KLO19986.1 - 0.0052 16.5 10.6 0.0092 15.7 10.6 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 KLO19986.1 - 0.011 15.6 4.0 0.017 15.0 4.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.6 KLO19986.1 - 0.019 15.3 12.5 0.041 14.3 12.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KLO19986.1 - 0.027 13.8 10.7 0.04 13.2 10.7 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.19 KLO19986.1 - 0.032 14.8 3.5 0.067 13.8 3.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein RXT2_N PF08595.11 KLO19986.1 - 0.041 13.9 6.1 0.067 13.2 6.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal TFB6 PF17110.5 KLO19986.1 - 0.097 12.4 7.1 0.17 11.6 7.1 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PPP4R2 PF09184.11 KLO19986.1 - 0.39 10.3 13.9 0.7 9.4 13.9 1.3 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KLO19986.1 - 0.58 8.3 8.1 0.77 7.9 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family FYDLN_acid PF09538.10 KLO19986.1 - 0.64 10.7 14.6 1.2 9.9 14.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Med13_C PF06333.12 KLO19986.1 - 0.79 8.9 10.6 1.4 8.1 10.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DNA_pol_phi PF04931.13 KLO19986.1 - 0.92 7.5 13.1 1.3 7.0 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi ORC6 PF05460.13 KLO19986.1 - 2.9 7.1 10.7 4.6 6.4 10.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CENP-B_dimeris PF09026.10 KLO19986.1 - 3.3 8.1 17.8 7.4 7.0 17.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RPN2_C PF18004.1 KLO19986.1 - 6.1 6.7 8.9 12 5.8 8.9 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4820 PF16091.5 KLO19986.1 - 7 5.9 5.9 12 5.2 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TLP-20 PF06088.11 KLO19986.1 - 8.2 6.3 8.3 16 5.4 8.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) B-block_TFIIIC PF04182.12 KLO19987.1 - 1.9e-10 40.7 0.4 3.1e-09 36.9 0.1 3.2 4 0 0 4 4 4 1 B-block binding subunit of TFIIIC UBN_AB PF14075.6 KLO19987.1 - 0.012 15.3 0.4 0.012 15.3 0.4 2.8 2 0 0 2 2 2 0 Ubinuclein conserved middle domain RPA_C PF08784.11 KLO19987.1 - 0.023 15.4 0.1 28 5.4 0.0 4.1 4 0 0 4 4 4 0 Replication protein A C terminal DUF3562 PF12085.8 KLO19987.1 - 0.095 12.3 0.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) Ntox47 PF15540.6 KLO19987.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial toxin 47 MADF_DNA_bdg PF10545.9 KLO19987.1 - 0.6 10.5 4.2 23 5.4 1.2 2.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Cnn_1N PF07989.11 KLO19987.1 - 1.2 9.4 5.9 0.13 12.4 0.2 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 PRELI PF04707.14 KLO19988.1 - 1e-45 155.3 0.0 1.2e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family DEAD PF00270.29 KLO19989.1 - 1.8e-37 128.8 0.0 3.3e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO19989.1 - 1.3e-25 89.9 0.0 5.6e-25 87.8 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO19989.1 - 3.9e-07 30.2 0.0 6.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KLO19989.1 - 0.048 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KLO19989.1 - 0.074 13.3 1.0 0.36 11.1 1.0 2.0 1 1 0 1 1 1 0 AAA domain Glyco_hydro_43 PF04616.14 KLO19990.1 - 8e-19 68.0 4.1 1.4e-18 67.2 4.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_35 PF16990.5 KLO19990.1 - 0.059 13.6 9.2 0.024 14.9 4.6 2.5 3 0 0 3 3 3 0 Carbohydrate binding module (family 35) RicinB_lectin_2 PF14200.6 KLO19990.1 - 2.7 8.8 7.5 1.1 10.0 0.4 3.2 2 2 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like DEAD PF00270.29 KLO19991.1 - 1.7e-36 125.7 0.1 2.7e-36 125.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO19991.1 - 1.2e-26 93.2 0.0 6.4e-25 87.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO19991.1 - 5.3e-09 36.3 0.0 9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HATPase_c PF02518.26 KLO19992.1 - 3.9e-29 101.4 0.3 9.2e-29 100.2 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KLO19992.1 - 5.9e-19 68.3 0.0 1.6e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain AAA_16 PF13191.6 KLO19992.1 - 4.2e-14 53.3 2.8 2e-12 47.8 1.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain HisKA PF00512.25 KLO19992.1 - 2.8e-13 49.7 0.0 1.4e-12 47.4 0.0 2.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KLO19992.1 - 2.7e-09 37.8 0.1 9.1e-09 36.0 0.1 2.0 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KLO19992.1 - 4.2e-09 36.2 0.0 8.4e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO19992.1 - 2.6e-06 26.9 0.0 7.2e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.6 KLO19992.1 - 0.00064 19.6 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Guanylate_kin PF00625.21 KLO19992.1 - 0.03 14.0 0.8 0.74 9.5 0.4 2.5 2 0 0 2 2 2 0 Guanylate kinase AAA_30 PF13604.6 KLO19992.1 - 0.095 12.4 0.3 0.28 10.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KLO19992.1 - 0.16 11.8 0.6 24 4.8 0.2 2.8 2 0 0 2 2 2 0 NACHT domain Yae1_N PF09811.9 KLO19994.1 - 0.0058 16.3 0.7 0.013 15.2 0.7 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal E1_dh PF00676.20 KLO19994.1 - 0.008 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component NTP_transferase PF00483.23 KLO19995.1 - 1.6e-41 142.5 0.0 4.1e-41 141.2 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KLO19995.1 - 2.5e-07 31.2 0.1 6.9e-07 29.8 0.1 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 KLO19995.1 - 3.4e-05 23.8 0.1 5.9e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase CCDC92 PF14916.6 KLO19995.1 - 0.11 12.2 0.3 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Las1 PF04031.13 KLO19996.1 - 1.2e-49 168.3 0.1 2.9e-49 167.1 0.1 1.6 1 0 0 1 1 1 1 Las1-like DnaB_bind PF10410.9 KLO19996.1 - 0.012 15.8 0.1 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase RTA1 PF04479.13 KLO19997.1 - 2.3e-05 24.1 6.1 3.3e-05 23.6 4.5 2.0 1 1 1 2 2 2 1 RTA1 like protein UL41A PF17591.2 KLO19997.1 - 0.27 11.4 1.6 0.57 10.3 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus UL41A CsbD PF05532.12 KLO19999.1 - 2.7e-13 49.6 14.0 1.4e-07 31.3 3.3 2.1 1 1 1 2 2 2 2 CsbD-like Pkinase PF00069.25 KLO20000.1 - 5.5e-05 22.7 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO20000.1 - 0.067 12.5 0.0 0.18 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein tyrosine kinase p450 PF00067.22 KLO20001.1 - 1.6e-53 182.2 0.0 1.9e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO20002.1 - 6.7e-46 157.0 0.0 7.9e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KLO20003.1 - 3.8e-08 33.0 0.0 8.9e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO20003.1 - 0.051 12.8 0.0 0.15 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein tyrosine kinase Flavoprotein PF02441.19 KLO20006.1 - 3.7e-51 173.0 0.0 4.2e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein DUF498 PF04430.14 KLO20006.1 - 0.065 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) SusD_RagB PF07980.11 KLO20007.1 - 0.0029 17.2 3.7 0.0042 16.7 2.5 1.8 2 0 0 2 2 2 1 SusD family CBM_19 PF03427.13 KLO20007.1 - 0.0034 17.3 3.7 0.0034 17.3 3.7 3.7 2 1 1 4 4 4 1 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 KLO20007.1 - 0.32 11.2 3.0 0.37 11.0 1.5 1.9 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Macoilin PF09726.9 KLO20007.1 - 5.8 5.3 9.3 6.5 5.2 9.3 1.1 1 0 0 1 1 1 0 Macoilin family HAD_2 PF13419.6 KLO20008.1 - 2.6e-22 79.8 0.0 3.4e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KLO20008.1 - 6.4e-12 46.2 0.0 5.2e-05 23.6 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO20008.1 - 1.4e-08 34.6 0.1 2.6e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KLO20008.1 - 0.036 14.5 0.6 0.055 13.9 0.3 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KLO20010.1 - 2.4e-31 109.1 0.0 3.5e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO20010.1 - 1.9e-20 73.2 0.0 2.6e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO20010.1 - 0.038 13.9 1.2 0.22 11.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO20010.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MOZ_SAS PF01853.18 KLO20011.1 - 4.3e-63 212.2 0.1 2.3e-59 200.1 0.1 2.2 2 0 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 KLO20011.1 - 3.7e-19 68.1 3.0 1.1e-09 37.8 0.3 2.6 2 0 0 2 2 2 2 MYST family zinc finger domain Pkinase PF00069.25 KLO20012.1 - 2.8e-55 187.5 0.0 3.9e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO20012.1 - 3e-25 89.0 0.1 5.1e-25 88.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO20012.1 - 1.7e-06 27.6 0.0 3.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO20012.1 - 0.028 14.4 0.0 2.1 8.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L19e PF01280.20 KLO20014.1 - 4e-61 205.3 9.3 4e-61 205.3 9.3 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e S4 PF01479.25 KLO20014.1 - 0.0032 17.1 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 S4 domain AAA PF00004.29 KLO20015.1 - 3.1e-42 144.1 0.0 5.4e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KLO20015.1 - 2.9e-28 97.6 0.4 8.4e-28 96.2 0.3 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KLO20015.1 - 1.8e-22 79.2 6.8 4.6e-22 77.8 6.8 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KLO20015.1 - 2.9e-07 30.2 0.1 1.8e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 KLO20015.1 - 1.4e-05 25.4 0.1 0.02 15.2 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 KLO20015.1 - 1.6e-05 25.4 0.2 0.0018 18.7 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KLO20015.1 - 3.4e-05 23.6 0.0 5.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KLO20015.1 - 3.8e-05 23.7 0.0 0.00014 21.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KLO20015.1 - 5.9e-05 22.9 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KLO20015.1 - 0.00012 21.4 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 KLO20015.1 - 0.00016 21.0 0.0 0.00088 18.5 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KLO20015.1 - 0.00016 21.7 0.0 0.00054 20.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KLO20015.1 - 0.00022 21.6 0.0 0.0084 16.5 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_18 PF13238.6 KLO20015.1 - 0.00049 20.6 0.0 0.0016 19.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KLO20015.1 - 0.00088 19.4 0.0 0.0042 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KLO20015.1 - 0.00096 19.3 0.2 0.005 17.0 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KLO20015.1 - 0.0027 17.5 0.0 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF4407 PF14362.6 KLO20015.1 - 0.004 16.5 1.8 0.0061 15.9 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) AAA_17 PF13207.6 KLO20015.1 - 0.0042 17.5 0.1 0.032 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KLO20015.1 - 0.0086 15.7 0.1 0.74 9.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 KLO20015.1 - 0.0086 15.6 0.3 0.11 12.0 0.0 2.6 2 1 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KLO20015.1 - 0.041 13.3 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KLO20015.1 - 0.046 13.1 0.5 7.4 5.8 0.0 2.9 2 1 1 3 3 3 0 KaiC Bac_DnaA PF00308.18 KLO20015.1 - 0.059 13.2 0.0 0.31 10.8 0.0 2.2 2 1 0 2 2 1 0 Bacterial dnaA protein Parvo_NS1 PF01057.17 KLO20015.1 - 0.061 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KLO20015.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 KLO20015.1 - 0.068 13.1 0.9 1.9 8.3 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Tma16 PF11176.8 KLO20015.1 - 0.088 12.7 0.8 0.31 10.9 0.6 1.9 2 0 0 2 2 2 0 Translation machinery-associated protein 16 NACHT PF05729.12 KLO20015.1 - 0.1 12.5 0.0 0.7 9.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Cut12 PF11500.8 KLO20015.1 - 0.11 12.5 3.0 0.2 11.6 3.0 1.4 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Torsin PF06309.11 KLO20015.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.26 KLO20015.1 - 0.15 11.8 0.0 0.41 10.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Abhydrolase_1 PF00561.20 KLO20016.1 - 1.9e-47 162.1 0.0 2.4e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KLO20016.1 - 0.51 10.9 10.8 1.1 9.8 10.8 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DHC_N1 PF08385.12 KLO20017.1 - 5.1e-130 434.8 10.0 2.6e-128 429.1 5.5 2.3 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 DUF848 PF05852.11 KLO20017.1 - 0.022 14.8 0.2 0.86 9.7 0.1 2.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Pro_3_hydrox_C PF05373.11 KLO20017.1 - 0.2 11.8 1.0 2.3 8.3 0.2 3.0 3 0 0 3 3 3 0 L-proline 3-hydroxylase, C-terminal adh_short PF00106.25 KLO20018.1 - 1.4e-28 99.7 0.1 4.6e-28 98.0 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO20018.1 - 1.3e-18 67.4 0.3 4.4e-11 42.8 0.3 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO20018.1 - 1.6e-08 34.6 3.1 2.3e-08 34.2 0.8 1.9 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 KLO20018.1 - 0.088 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KLO20018.1 - 0.091 12.2 0.0 8.2 5.8 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family EspB PF05802.11 KLO20019.1 - 0.08 12.9 11.1 0.096 12.7 11.1 1.0 1 0 0 1 1 1 0 Enterobacterial EspB protein zf-MYND PF01753.18 KLO20020.1 - 3.3e-07 30.3 14.9 6.4e-07 29.4 14.9 1.5 1 0 0 1 1 1 1 MYND finger Caerin_1 PF07440.12 KLO20020.1 - 0.15 12.1 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Caerin 1 protein DLH PF01738.18 KLO20021.1 - 1.5e-12 47.6 0.0 1.9e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family F-box-like PF12937.7 KLO20022.1 - 0.00011 22.0 0.9 0.00024 20.9 0.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO20022.1 - 0.14 12.0 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 F-box domain Prenylcys_lyase PF07156.14 KLO20023.1 - 8.8e-73 245.5 0.0 1.2e-72 245.1 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 KLO20023.1 - 7.3e-10 38.7 0.0 9.8e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KLO20023.1 - 1.9e-09 37.6 0.0 4.7e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KLO20023.1 - 6.6e-05 22.7 2.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KLO20023.1 - 0.018 14.3 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KLO20023.1 - 0.12 12.3 0.0 0.96 9.4 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ammonium_transp PF00909.21 KLO20024.1 - 9.2e-119 396.7 17.8 1.1e-118 396.5 17.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family NAD_binding_8 PF13450.6 KLO20024.1 - 0.1 12.8 0.0 0.36 11.1 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Tim17 PF02466.19 KLO20024.1 - 7.5 7.0 8.6 6 7.3 3.4 3.1 1 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family CTP_transf_like PF01467.26 KLO20025.1 - 4.2e-24 85.4 0.0 7.7e-19 68.3 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like RAWUL PF16207.5 KLO20026.1 - 0.087 13.5 0.1 0.15 12.8 0.1 1.5 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like SAPI PF16560.5 KLO20026.1 - 0.12 11.9 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Putative mobile pathogenicity island Proteasome PF00227.26 KLO20027.1 - 1e-37 129.5 0.0 1.2e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SKG6 PF08693.10 KLO20028.1 - 0.0088 15.4 1.6 0.022 14.1 1.6 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KLO20028.1 - 0.093 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.6 KLO20028.1 - 3.7 7.5 12.3 58 3.6 12.3 2.5 1 1 0 1 1 1 0 TMEM154 protein family DUF155 PF02582.14 KLO20029.1 - 2.5e-54 184.1 0.5 6.5e-54 182.7 0.2 1.8 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 BUD22 PF09073.10 KLO20029.1 - 4.4 6.5 8.8 0.16 11.2 3.0 1.5 2 0 0 2 2 2 0 BUD22 GHMP_kinases_N PF00288.26 KLO20031.1 - 2.4e-10 40.5 0.9 4.6e-10 39.6 0.9 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KLO20031.1 - 0.011 16.0 0.0 0.031 14.6 0.0 1.8 1 0 0 1 1 1 0 GHMP kinases C terminal Romo1 PF10247.9 KLO20033.1 - 2e-24 85.7 11.4 2.8e-24 85.3 11.4 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Pex2_Pex12 PF04757.14 KLO20034.1 - 1.2e-25 90.4 2.7 2e-25 89.7 2.7 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KLO20034.1 - 3.3e-10 39.7 5.1 4.6e-10 39.2 5.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO20034.1 - 1.2e-08 34.7 7.0 1.8e-08 34.1 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO20034.1 - 1.3e-08 35.0 8.8 2e-08 34.4 8.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KLO20034.1 - 3.9e-08 33.0 7.0 6.2e-08 32.4 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KLO20034.1 - 2.5e-07 30.4 6.1 4e-07 29.8 6.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KLO20034.1 - 1.2e-06 28.4 6.6 1.8e-06 27.8 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KLO20034.1 - 2.1e-06 27.6 3.0 2.3e-06 27.5 1.5 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KLO20034.1 - 3e-06 27.4 5.2 5.5e-06 26.6 5.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KLO20034.1 - 8.9e-05 22.6 7.6 0.00016 21.7 7.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KLO20034.1 - 0.0053 16.8 1.5 0.0091 16.0 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KLO20034.1 - 0.01 16.0 4.6 0.018 15.2 4.6 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KLO20034.1 - 0.11 12.3 5.9 0.22 11.4 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TerY_C PF15616.6 KLO20034.1 - 0.16 12.1 2.6 0.3 11.2 2.6 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-Nse PF11789.8 KLO20034.1 - 0.29 11.0 1.4 0.47 10.3 1.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.21 KLO20034.1 - 2.1 8.6 7.8 2.4 8.5 6.7 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain AAA_6 PF12774.7 KLO20035.1 - 2.5e-127 424.4 0.0 3.2e-126 420.7 0.0 2.9 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KLO20035.1 - 9.5e-114 380.6 7.7 9.5e-114 380.6 7.7 3.5 4 1 1 5 5 2 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KLO20035.1 - 7.5e-74 247.6 0.5 7.5e-74 247.6 0.5 4.1 4 1 0 5 5 5 1 ATP-binding dynein motor region AAA_8 PF12780.7 KLO20035.1 - 1.2e-68 231.2 0.0 3.4e-68 229.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KLO20035.1 - 4.1e-49 167.5 0.0 4.1e-49 167.5 0.0 2.1 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KLO20035.1 - 8.3e-46 155.8 0.0 2.6e-38 131.3 0.0 5.4 5 0 0 5 5 5 2 P-loop containing dynein motor region MT PF12777.7 KLO20035.1 - 2e-42 145.5 5.7 3.6e-42 144.6 5.7 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KLO20035.1 - 7.9e-37 126.6 0.0 1.7e-36 125.5 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KLO20035.1 - 6.5e-29 100.4 0.0 7.1e-28 97.1 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KLO20035.1 - 3.5e-28 98.3 0.0 1.4e-12 47.8 0.0 6.1 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KLO20035.1 - 1.7e-16 60.4 0.3 3.6e-15 56.2 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KLO20035.1 - 1.8e-14 54.3 0.0 0.0015 19.0 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KLO20035.1 - 1.6e-13 51.1 0.1 0.0043 17.3 0.0 5.5 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 KLO20035.1 - 1e-11 45.1 0.0 0.024 14.8 0.0 5.0 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.6 KLO20035.1 - 7.5e-10 39.4 0.0 0.61 10.5 0.0 6.1 5 0 0 5 5 5 2 AAA ATPase domain AAA_18 PF13238.6 KLO20035.1 - 2e-08 34.9 0.0 0.057 14.0 0.0 5.4 4 0 0 4 4 4 2 AAA domain Mg_chelatase PF01078.21 KLO20035.1 - 2.9e-06 26.8 1.1 0.66 9.3 0.0 4.4 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 KLO20035.1 - 8.2e-06 25.1 0.0 0.02 14.0 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_19 PF13245.6 KLO20035.1 - 1.4e-05 25.4 0.8 0.31 11.4 0.0 4.7 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.18 KLO20035.1 - 2.1e-05 24.0 0.0 0.097 12.0 0.0 3.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_30 PF13604.6 KLO20035.1 - 3.7e-05 23.5 0.7 3.8 7.2 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_lid_1 PF17857.1 KLO20035.1 - 7e-05 23.0 0.6 0.00043 20.4 0.0 2.8 2 0 0 2 2 1 1 AAA+ lid domain IstB_IS21 PF01695.17 KLO20035.1 - 0.00025 20.8 0.8 0.79 9.4 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_14 PF13173.6 KLO20035.1 - 0.00051 20.1 0.0 2.6 8.1 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KLO20035.1 - 0.0015 18.2 0.0 0.71 9.7 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KLO20035.1 - 0.0032 17.2 0.3 23 4.6 0.0 4.5 4 0 0 4 4 4 0 AAA domain CheR_N PF03705.15 KLO20035.1 - 0.0065 16.2 0.6 0.91 9.3 1.2 3.0 2 0 0 2 2 2 1 CheR methyltransferase, all-alpha domain Rad17 PF03215.15 KLO20035.1 - 0.0072 16.3 0.0 24 4.8 0.0 4.4 4 0 0 4 4 4 0 Rad17 P-loop domain RNA_helicase PF00910.22 KLO20035.1 - 0.0078 16.6 0.0 26 5.3 0.0 4.4 4 0 0 4 4 4 0 RNA helicase AAA_11 PF13086.6 KLO20035.1 - 0.0084 15.9 10.6 1.3 8.7 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 KLO20035.1 - 0.012 15.1 0.0 0.65 9.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 KLO20035.1 - 0.02 14.7 0.0 10 5.8 0.0 3.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 KLO20035.1 - 0.022 14.7 0.1 15 5.6 0.0 4.0 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KLO20035.1 - 0.057 13.2 0.0 2.9 7.6 0.0 3.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain DUF3087 PF11286.8 KLO20035.1 - 0.1 12.1 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) ABC_tran PF00005.27 KLO20035.1 - 0.11 13.0 7.2 12 6.4 0.0 4.8 5 0 0 5 5 3 0 ABC transporter SRP54 PF00448.22 KLO20035.1 - 0.18 11.4 2.3 42 3.7 0.1 3.9 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain NACHT PF05729.12 KLO20035.1 - 1.4 8.9 5.2 39 4.1 0.1 4.9 6 0 0 6 6 3 0 NACHT domain DUF4407 PF14362.6 KLO20035.1 - 1.7 8.0 17.0 2.6 7.3 9.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.11 KLO20035.1 - 2.7 7.8 25.0 0.53 10.1 10.6 4.0 4 0 0 4 4 3 0 Phage minor structural protein GP20 Med9 PF07544.13 KLO20036.1 - 4.1e-07 30.0 0.7 7e-07 29.3 0.7 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 ECM11 PF15463.6 KLO20036.1 - 0.083 13.5 0.6 0.17 12.5 0.6 1.7 1 1 0 1 1 1 0 Extracellular mutant protein 11 PrpR_N PF06506.11 KLO20036.1 - 0.092 12.3 0.2 0.22 11.1 0.0 1.7 2 1 0 2 2 2 0 Propionate catabolism activator GST_N PF02798.20 KLO20037.1 - 8.5e-22 77.3 0.0 1.6e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KLO20037.1 - 6.3e-18 65.0 0.0 9.7e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO20037.1 - 1.6e-12 47.6 0.0 2.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KLO20037.1 - 1.6e-11 44.3 0.0 2.9e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KLO20037.1 - 1.4e-07 31.7 0.0 2.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KLO20037.1 - 0.0024 17.9 0.0 0.0068 16.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aldose_epim PF01263.20 KLO20038.1 - 9e-32 110.6 0.0 1e-31 110.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RINT1_TIP1 PF04437.13 KLO20039.1 - 3.7e-93 313.1 0.0 4.3e-92 309.6 0.0 2.2 2 0 0 2 2 2 1 RINT-1 / TIP-1 family DUF4200 PF13863.6 KLO20039.1 - 0.027 14.9 3.8 0.084 13.3 3.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Pro_CA PF00484.19 KLO20040.1 - 7.8e-15 55.5 0.2 1.7e-14 54.4 0.2 1.5 1 1 0 1 1 1 1 Carbonic anhydrase NT5C PF06941.12 KLO20041.1 - 1.1e-11 45.0 0.3 2.8e-11 43.6 0.3 1.7 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.6 KLO20041.1 - 0.13 12.3 0.1 0.27 11.3 0.1 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase NT5C PF06941.12 KLO20042.1 - 1.8e-09 37.8 2.6 1.1e-08 35.2 0.2 2.5 3 0 0 3 3 3 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD PF12710.7 KLO20042.1 - 0.0019 18.6 0.0 0.0028 18.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KLO20042.1 - 0.0098 16.0 0.0 0.044 13.9 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KLO20042.1 - 0.029 14.6 0.1 0.33 11.2 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KLO20042.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF3445 PF11927.8 KLO20043.1 - 6.9e-62 209.0 0.0 8.7e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ABC_membrane_2 PF06472.15 KLO20044.1 - 4.3e-83 278.8 0.7 6.8e-83 278.2 0.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KLO20044.1 - 6.1e-17 62.4 0.0 1.5e-16 61.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KLO20044.1 - 0.00013 21.8 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KLO20044.1 - 0.003 18.1 0.1 0.012 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KLO20044.1 - 0.044 13.7 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain SMC_N PF02463.19 KLO20044.1 - 0.044 13.2 0.1 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KLO20044.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KLO20044.1 - 0.084 12.6 0.2 0.55 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KLO20044.1 - 0.13 11.8 0.0 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region PolyA_pol PF01743.20 KLO20045.1 - 2.1e-25 89.6 0.0 3.4e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KLO20045.1 - 6.8e-09 35.4 0.0 1.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KLO20045.1 - 0.026 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Abhydrolase_2 PF02230.16 KLO20046.1 - 1.3e-32 113.4 0.0 1.5e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 KLO20046.1 - 0.086 12.4 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family COX6A PF02046.15 KLO20047.1 - 1.5e-27 96.3 0.2 1.8e-27 96.1 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa F-box PF00646.33 KLO20048.1 - 0.041 13.8 0.7 1.3 9.0 0.1 3.2 3 0 0 3 3 3 0 F-box domain PGP_phosphatase PF09419.10 KLO20050.1 - 1.4e-41 141.9 0.0 1.8e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KLO20050.1 - 0.034 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like DAO PF01266.24 KLO20051.1 - 5.7e-36 124.8 0.2 7.3e-36 124.5 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 KLO20051.1 - 0.00044 19.9 0.0 0.0019 17.8 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KLO20051.1 - 0.003 18.1 0.0 0.031 14.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KLO20051.1 - 0.0061 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KLO20051.1 - 0.0087 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Sacchrp_dh_NADP PF03435.18 KLO20051.1 - 0.0099 16.1 0.0 0.05 13.9 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KLO20051.1 - 0.023 15.2 0.0 0.052 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KLO20051.1 - 0.029 14.4 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KLO20051.1 - 0.041 14.1 0.1 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 KLO20051.1 - 0.054 12.7 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KLO20051.1 - 0.12 11.8 0.0 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus ATP-synt_Z PF16594.5 KLO20051.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated RRM_1 PF00076.22 KLO20052.1 - 6e-26 90.1 0.0 2e-13 50.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KLO20052.1 - 6.1e-13 48.5 0.0 1.1e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KLO20052.1 - 1.1e-05 25.2 0.0 9.2e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KLO20052.1 - 0.011 15.8 0.0 0.09 12.9 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 LysM PF01476.20 KLO20053.1 - 4.3e-13 49.1 0.0 6.7e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 LysM domain Imm27 PF15590.6 KLO20053.1 - 0.49 10.2 2.6 4.5 7.1 0.3 2.5 1 1 1 2 2 2 0 Immunity protein 27 MARVEL PF01284.23 KLO20054.1 - 2.9e-05 24.1 17.3 3.6e-05 23.8 17.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain Nop14 PF04147.12 KLO20055.1 - 0.00066 18.1 0.4 0.00066 18.1 0.4 1.5 2 0 0 2 2 2 1 Nop14-like family WYL_3 PF18488.1 KLO20055.1 - 0.059 13.8 0.1 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 WYL domain TatD_DNase PF01026.21 KLO20056.1 - 1.8e-24 86.5 0.0 2.3e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Met_10 PF02475.16 KLO20057.1 - 7.8e-63 211.8 0.0 2.1e-62 210.5 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein MethyltransfD12 PF02086.15 KLO20057.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.16 KLO20057.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase tRNA_U5-meth_tr PF05958.11 KLO20057.1 - 0.014 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KLO20057.1 - 0.073 12.6 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 KLO20057.1 - 0.094 13.4 0.0 0.24 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Mito_carr PF00153.27 KLO20058.1 - 3.4e-71 235.2 1.1 1.3e-23 82.7 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KLO20058.1 - 8.5e-17 59.4 6.4 1.9e-05 23.8 0.1 6.2 6 0 0 6 6 6 2 EF hand EF-hand_7 PF13499.6 KLO20058.1 - 6.8e-16 58.5 7.2 1e-06 29.1 0.1 5.4 3 3 2 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 KLO20058.1 - 2.3e-15 55.1 7.9 5.6e-06 25.9 0.2 5.8 7 0 0 7 7 7 2 EF-hand domain EF-hand_8 PF13833.6 KLO20058.1 - 9.2e-11 41.4 2.0 0.0014 18.5 0.0 5.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KLO20058.1 - 1.3e-07 30.8 8.3 0.00062 19.1 0.3 4.1 4 0 0 4 4 4 2 EF hand Caleosin PF05042.13 KLO20058.1 - 0.081 12.8 0.1 0.99 9.3 0.0 2.6 3 0 0 3 3 3 0 Caleosin related protein DUF953 PF06110.11 KLO20060.1 - 1.5e-10 40.8 0.0 1.8e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Amidase PF01425.21 KLO20061.1 - 2.8e-102 343.0 0.0 4.6e-102 342.3 0.0 1.3 1 1 0 1 1 1 1 Amidase Acetyltransf_10 PF13673.7 KLO20062.1 - 1.1e-09 38.3 0.0 2.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KLO20062.1 - 1.1e-08 35.0 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KLO20062.1 - 5e-07 30.0 0.0 8.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KLO20062.1 - 5.6e-07 29.8 0.0 9.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KLO20062.1 - 2.3e-06 27.7 0.0 5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KLO20062.1 - 0.0061 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KLO20062.1 - 0.035 14.2 0.1 0.07 13.3 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MoaC PF01967.21 KLO20063.1 - 3.4e-46 156.7 0.2 6.8e-46 155.7 0.2 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KLO20063.1 - 4e-38 130.2 0.0 8.2e-38 129.2 0.0 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KLO20063.1 - 2.8e-27 96.1 0.1 4.6e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KLO20063.1 - 8.4e-07 29.3 0.0 2.3e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KLO20063.1 - 0.0016 18.6 0.0 0.0046 17.1 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain DCAF15_WD40 PF14939.6 KLO20064.1 - 0.041 13.5 0.0 0.051 13.2 0.0 1.1 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat NIPSNAP PF07978.13 KLO20066.1 - 1.7e-33 114.9 0.7 3e-27 94.8 0.1 2.2 2 0 0 2 2 2 2 NIPSNAP Forkhead PF00250.18 KLO20067.1 - 2.2e-19 69.5 0.0 2.4e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain WD40 PF00400.32 KLO20068.1 - 6.5e-59 194.5 20.4 4.3e-06 27.3 0.0 11.4 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.11 KLO20068.1 - 8.1e-45 152.2 0.0 1.3e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KLO20068.1 - 2.2e-12 47.1 1.5 0.8 10.0 0.0 7.9 6 1 2 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KLO20068.1 - 7e-06 25.6 2.9 0.00055 19.4 0.0 4.0 5 0 0 5 5 5 1 WD40-like domain Nup160 PF11715.8 KLO20068.1 - 1.4e-05 24.0 14.1 0.58 8.7 0.5 6.3 3 3 2 7 7 7 4 Nucleoporin Nup120/160 MMS1_N PF10433.9 KLO20068.1 - 0.011 14.5 2.7 0.71 8.4 0.0 3.4 3 1 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PALB2_WD40 PF16756.5 KLO20068.1 - 0.044 12.7 0.4 0.15 11.0 0.2 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Peptidase_M24 PF00557.24 KLO20070.1 - 3.6e-45 154.2 0.0 4.5e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Coilin_N PF15862.5 KLO20070.1 - 0.043 13.6 3.7 2.2 8.1 0.0 2.9 2 1 1 3 3 3 0 Coilin N-terminus YL1 PF05764.13 KLO20070.1 - 0.24 11.5 5.9 0.36 10.9 5.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PGA2 PF07543.12 KLO20070.1 - 4.8 7.2 12.5 2.3 8.2 3.9 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Abhydrolase_3 PF07859.13 KLO20071.1 - 7.6e-47 159.9 0.0 1.3e-46 159.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KLO20071.1 - 3.9e-19 68.7 0.0 5.7e-18 64.9 0.0 2.0 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KLO20071.1 - 0.0007 18.6 0.0 0.47 9.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 KLO20071.1 - 0.02 14.4 0.0 0.065 12.7 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KLO20071.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Exo_endo_phos PF03372.23 KLO20072.1 - 8.5e-16 58.2 0.0 1.2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTF2 PF02136.20 KLO20073.1 - 1e-14 55.1 0.0 2.4e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KLO20073.1 - 3.1e-06 27.2 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DBP10CT PF08147.12 KLO20078.1 - 0.011 15.9 1.5 0.13 12.5 0.4 2.2 1 1 1 2 2 2 0 DBP10CT (NUC160) domain U62_UL91 PF17442.2 KLO20081.1 - 0.094 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins DUF2481 PF10654.9 KLO20081.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) Agglutinin_C PF18021.1 KLO20083.1 - 0.0073 16.8 0.0 1.3 9.6 0.0 2.4 1 1 1 2 2 2 2 Agglutinin C-terminal CENP-T_C PF15511.6 KLO20087.1 - 1.2e-06 28.6 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KLO20087.1 - 2e-05 24.6 0.1 2.9e-05 24.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KLO20087.1 - 0.00017 21.9 0.0 0.00021 21.6 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KLO20087.1 - 0.0015 18.8 0.1 0.0027 17.9 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KLO20087.1 - 0.0034 17.7 0.2 0.0039 17.6 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KLO20087.1 - 0.049 13.7 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KLO20087.1 - 0.057 13.4 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated RibD_C PF01872.17 KLO20088.1 - 4.9e-38 131.0 0.1 5.8e-38 130.7 0.1 1.1 1 0 0 1 1 1 1 RibD C-terminal domain N_BRCA1_IG PF16158.5 KLO20089.1 - 2.8e-76 252.7 0.0 6.1e-28 97.5 0.0 4.0 3 0 0 3 3 3 3 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KLO20089.1 - 5.3e-35 119.0 43.1 1.7e-09 37.3 6.1 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KLO20089.1 - 1.6e-07 31.6 40.8 0.0012 19.2 2.9 4.8 5 0 0 5 5 5 4 C1 domain RhoGEF PF00621.20 KLO20090.1 - 7.6e-13 49.1 0.0 7.7e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 RhoGEF domain Peptidase_S80 PF07230.11 KLO20090.1 - 0.19 10.0 0.0 0.29 9.4 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) PUF PF00806.19 KLO20091.1 - 5.4e-29 98.2 0.4 2.7e-08 33.1 0.1 6.0 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat DUF900 PF05990.12 KLO20091.1 - 0.031 13.8 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) CPL PF08144.11 KLO20091.1 - 0.13 12.6 0.0 5.3 7.4 0.0 3.0 3 0 0 3 3 3 0 CPL (NUC119) domain Glyco_hydro_28 PF00295.17 KLO20092.1 - 1.1e-44 152.8 1.5 1.1e-44 152.8 1.5 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 CBM_4_9 PF02018.17 KLO20092.1 - 0.018 15.3 0.3 0.54 10.5 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate binding domain NmrA PF05368.13 KLO20093.1 - 3.7e-17 62.7 0.0 5.4e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KLO20093.1 - 3.9e-17 62.7 0.0 5.4e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KLO20093.1 - 0.006 16.1 0.0 0.019 14.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO20093.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Chorismate_bind PF00425.18 KLO20094.1 - 4.7e-68 229.5 0.0 7.3e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KLO20094.1 - 1.2e-29 103.5 0.0 1.9e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KLO20094.1 - 2.8e-15 56.8 0.0 1.3e-14 54.6 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KLO20094.1 - 4.1e-06 26.7 0.3 8.9e-06 25.6 0.3 1.5 1 0 0 1 1 1 1 Peptidase C26 Transthyretin PF00576.21 KLO20095.1 - 8.1e-36 123.1 0.0 9.9e-36 122.8 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family UQ_con PF00179.26 KLO20096.1 - 2.6e-38 130.8 0.2 3.4e-38 130.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KLO20096.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KLO20096.1 - 0.37 11.1 1.5 0.59 10.4 1.2 1.7 1 1 0 1 1 1 0 RWD domain DIOX_N PF14226.6 KLO20097.1 - 5.5e-05 23.9 0.0 9.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KLO20097.1 - 6e-05 23.5 0.0 0.0001 22.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AA_permease_2 PF13520.6 KLO20098.1 - 4.9e-56 190.4 41.7 6.6e-56 189.9 41.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KLO20098.1 - 1.2e-19 70.3 33.0 1.2e-19 70.3 33.0 1.5 2 0 0 2 2 2 1 Amino acid permease DUF5056 PF16479.5 KLO20098.1 - 0.24 11.6 1.4 25 5.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) DUF4234 PF14018.6 KLO20098.1 - 0.56 10.4 3.5 50 4.1 0.4 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) Nop52 PF05997.12 KLO20099.1 - 2.5e-73 246.4 0.0 3.5e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.6 KLO20099.1 - 7.2e-06 25.8 0.0 3.3e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II TAN PF11640.8 KLO20099.1 - 0.022 14.9 0.0 0.049 13.8 0.0 1.6 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair ATP11 PF06644.11 KLO20099.1 - 0.037 13.8 0.8 0.064 13.0 0.1 1.6 2 0 0 2 2 2 0 ATP11 protein DUF2235 PF09994.9 KLO20100.1 - 3.2e-88 295.8 0.0 4.1e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KLO20100.1 - 0.021 14.8 0.1 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Palm_thioest PF02089.15 KLO20100.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ribosomal_L28e PF01778.17 KLO20101.1 - 8.2e-29 100.7 0.3 1.1e-28 100.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family DAP PF15228.6 KLO20102.1 - 0.0074 17.4 9.7 0.018 16.2 9.7 1.7 1 1 0 1 1 1 1 Death-associated protein O-FucT PF10250.9 KLO20103.1 - 1.8e-05 24.6 0.0 2.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase O-FucT PF10250.9 KLO20104.1 - 6.7e-12 45.7 0.0 4e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase DUF5010 PF16402.5 KLO20104.1 - 0.002 17.1 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5010) RhoGEF PF00621.20 KLO20105.1 - 1.4e-36 126.5 0.0 1.9e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 KLO20105.1 - 3.7e-17 62.2 10.3 6.2e-17 61.5 10.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KLO20105.1 - 9.6e-06 26.1 0.1 5.3e-05 23.7 0.1 2.2 1 1 0 1 1 1 1 PH domain GPP34 PF05719.11 KLO20105.1 - 0.046 13.8 0.9 10 6.1 0.0 3.4 3 1 0 3 3 3 0 Golgi phosphoprotein 3 (GPP34) FYVE_2 PF02318.16 KLO20105.1 - 3.3 8.0 7.0 6.5 7.0 7.0 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Lgl_C PF08596.10 KLO20106.1 - 1.9e-38 132.2 0.0 4.8e-38 130.9 0.0 1.7 1 1 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 KLO20106.1 - 0.074 13.4 0.0 88 3.5 0.0 4.9 6 0 0 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KLO20106.1 - 0.14 11.8 0.0 2.7 7.7 0.0 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split DUF1115 PF06544.12 KLO20107.1 - 6.5e-08 32.8 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Acylphosphatase PF00708.18 KLO20107.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Acylphosphatase DUF2358 PF10184.9 KLO20108.1 - 0.0009 19.5 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) RRM_1 PF00076.22 KLO20109.1 - 2.1e-17 62.7 0.0 2.8e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KLO20109.1 - 0.00052 19.6 0.0 0.0007 19.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KLO20109.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 O-FucT PF10250.9 KLO20110.1 - 1.2e-09 38.3 0.0 2.3e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase COX5A PF02284.16 KLO20111.1 - 2.6e-42 143.0 0.1 3.2e-42 142.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Nramp PF01566.18 KLO20112.1 - 3e-86 289.6 20.8 5.3e-51 173.7 5.3 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Utp14 PF04615.13 KLO20113.1 - 1.1e-189 632.7 64.5 1.1e-189 632.7 64.5 2.8 1 1 1 2 2 2 1 Utp14 protein Amidohydro_3 PF07969.11 KLO20114.1 - 1.7e-12 47.6 0.4 1.9e-05 24.3 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KLO20114.1 - 3.1e-12 46.5 0.2 2e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.12 KLO20114.1 - 5e-08 32.7 0.0 0.0035 17.2 0.0 4.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Adap_comp_sub PF00928.21 KLO20115.1 - 1.6e-20 73.6 0.0 2.2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KLO20115.1 - 2.2e-06 27.6 0.1 4.2e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2457 PF10446.9 KLO20115.1 - 0.11 11.7 1.4 0.14 11.3 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) F-box-like PF12937.7 KLO20116.1 - 0.00024 20.9 0.1 0.00068 19.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO20116.1 - 0.00037 20.3 0.0 0.00097 19.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain Amidohydro_1 PF01979.20 KLO20117.1 - 2.3e-20 73.2 0.3 6.4e-17 61.9 0.0 3.6 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KLO20117.1 - 6e-10 39.2 0.8 1.6e-05 24.6 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Hira PF07569.11 KLO20118.1 - 3.4e-54 183.9 0.1 9.4e-54 182.5 0.1 1.8 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 KLO20118.1 - 6.2e-30 102.8 22.7 3.4e-06 27.7 0.2 10.0 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO20118.1 - 7.8e-13 48.6 1.3 0.27 11.5 0.0 7.7 4 3 3 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 KLO20118.1 - 0.0052 16.2 0.1 0.01 15.2 0.1 1.4 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region SAGA-Tad1 PF12767.7 KLO20122.1 - 0.6 9.8 8.1 0.76 9.5 5.6 2.0 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit AATF-Che1 PF13339.6 KLO20122.1 - 1.1 10.0 12.7 0.42 11.3 3.7 2.7 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor XRN_M PF17846.1 KLO20122.1 - 4 6.3 8.8 26 3.6 0.0 2.1 1 1 1 2 2 2 0 Xrn1 helical domain FMO-like PF00743.19 KLO20123.1 - 7.3e-41 140.2 0.0 8.5e-30 103.7 0.0 2.5 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KLO20123.1 - 3.2e-08 33.2 0.1 7.5e-05 22.1 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KLO20123.1 - 1.9e-07 30.6 0.0 5.3e-06 25.9 0.0 2.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KLO20123.1 - 2.9e-07 30.0 0.1 5.1e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KLO20123.1 - 4.1e-06 26.9 2.0 0.0002 21.4 0.3 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KLO20123.1 - 0.0013 18.9 0.6 0.0044 17.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KLO20123.1 - 0.067 12.4 0.0 0.9 8.7 0.0 2.1 2 0 0 2 2 2 0 Thi4 family NGP1NT PF08153.12 KLO20124.1 - 4.7e-51 172.3 0.0 9.6e-51 171.3 0.0 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KLO20124.1 - 1.7e-17 63.5 0.3 6e-14 52.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KLO20124.1 - 3.8e-05 23.3 0.4 0.00022 20.8 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KLO20124.1 - 8.9e-05 22.4 0.0 0.00026 20.9 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KLO20124.1 - 0.0003 20.4 0.0 0.034 13.7 0.0 2.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain BUD22 PF09073.10 KLO20124.1 - 0.00058 19.3 10.3 0.0011 18.5 10.3 1.4 1 0 0 1 1 1 1 BUD22 Arf PF00025.21 KLO20124.1 - 0.039 13.4 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 KLO20124.1 - 0.08 13.0 1.0 7.4 6.6 0.1 3.4 2 1 1 3 3 3 0 Dynamin family IBN_N PF03810.19 KLO20126.1 - 1.1e-08 34.8 0.3 3.6e-05 23.6 0.0 4.1 4 1 1 5 5 5 1 Importin-beta N-terminal domain HEAT PF02985.22 KLO20126.1 - 0.0017 18.5 6.7 0.035 14.4 0.1 5.7 7 0 0 7 7 7 1 HEAT repeat Adaptin_N PF01602.20 KLO20126.1 - 0.0045 15.6 0.8 0.03 12.9 0.2 2.4 2 1 0 2 2 2 1 Adaptin N terminal region Xpo1 PF08389.12 KLO20126.1 - 0.0064 16.6 0.2 0.25 11.4 0.1 3.7 2 2 0 2 2 2 1 Exportin 1-like protein ParcG PF10274.9 KLO20126.1 - 0.014 15.5 1.3 7.4 6.6 0.1 2.9 3 0 0 3 3 3 0 Parkin co-regulated protein CAS_CSE1 PF03378.15 KLO20126.1 - 0.024 13.1 3.4 0.028 12.9 0.0 2.7 4 0 0 4 4 4 0 CAS/CSE protein, C-terminus DUF3385 PF11865.8 KLO20126.1 - 0.035 14.0 1.0 0.4 10.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) API5 PF05918.11 KLO20126.1 - 0.044 12.6 0.0 0.1 11.4 0.0 1.6 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Cse1 PF08506.10 KLO20126.1 - 0.11 11.4 0.0 0.24 10.2 0.0 1.7 1 0 0 1 1 1 0 Cse1 HEAT_EZ PF13513.6 KLO20126.1 - 0.15 12.6 9.6 42 4.8 0.0 6.5 6 2 1 7 7 7 0 HEAT-like repeat F-box-like PF12937.7 KLO20127.1 - 0.00014 21.6 0.9 0.00032 20.5 0.9 1.6 1 0 0 1 1 1 1 F-box-like Dor1 PF04124.12 KLO20129.1 - 7.9e-63 212.2 5.3 1e-62 211.8 5.3 1.1 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 KLO20129.1 - 2.2e-05 24.4 0.0 6.5e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Inositol_P PF00459.25 KLO20130.1 - 7.6e-63 212.6 0.0 9.1e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Proteasome PF00227.26 KLO20131.1 - 7.3e-58 195.2 0.1 9.3e-58 194.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KLO20131.1 - 7e-14 51.2 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribonuc_L-PSP PF01042.21 KLO20132.1 - 9.3e-39 132.2 0.2 1e-38 132.0 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP RPN1_RPN2_N PF17781.1 KLO20132.1 - 0.016 14.7 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain Mt_ATP-synt_D PF05873.12 KLO20132.1 - 0.046 13.6 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) UCH PF00443.29 KLO20134.1 - 3.8e-41 141.3 0.0 2.1e-40 138.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KLO20134.1 - 4.5e-22 77.7 0.4 1.7e-16 59.9 0.0 2.7 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.6 KLO20134.1 - 1.3e-05 25.0 9.8 0.00026 20.7 9.8 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FPP PF05911.11 KLO20134.1 - 0.014 13.6 1.0 0.022 13.0 1.0 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF2802 PF10975.8 KLO20134.1 - 0.052 13.7 0.2 1 9.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Bcr-Abl_Oligo PF09036.10 KLO20134.1 - 0.063 13.3 0.6 7.4 6.7 0.3 2.8 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain APG6_N PF17675.1 KLO20134.1 - 0.35 11.4 4.9 1.4 9.4 4.9 2.1 1 0 0 1 1 1 0 Apg6 coiled-coil region BST2 PF16716.5 KLO20134.1 - 2.3 8.9 4.9 7.6 7.2 4.9 2.0 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 p450 PF00067.22 KLO20136.1 - 9.8e-76 255.3 0.0 1.3e-75 254.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO20137.1 - 2.2e-73 247.6 0.0 3.3e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_15 PF01793.16 KLO20138.1 - 1.3e-116 389.5 10.5 1.4e-116 389.3 10.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF5106 PF17127.4 KLO20138.1 - 0.11 12.8 0.6 0.19 12.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) RseC_MucC PF04246.12 KLO20140.1 - 3.5 7.6 7.7 0.48 10.4 0.8 2.8 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC zf-CCHC PF00098.23 KLO20141.1 - 0.00035 20.5 1.1 0.00035 20.5 1.1 2.0 3 0 0 3 3 3 1 Zinc knuckle SRP-alpha_N PF04086.13 KLO20141.1 - 0.063 13.2 4.8 0.12 12.3 4.8 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 KLO20141.1 - 0.42 8.9 8.6 0.59 8.3 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Phage_int_SAM_3 PF14659.6 KLO20142.1 - 0.091 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 KLO20142.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.6 1 1 0 1 1 1 0 Phage integrase family F-box PF00646.33 KLO20143.1 - 0.023 14.6 0.2 0.054 13.4 0.2 1.7 1 0 0 1 1 1 0 F-box domain DUF3090 PF11290.8 KLO20143.1 - 0.12 12.1 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) Ribosomal_S15 PF00312.22 KLO20144.1 - 1.9e-22 79.2 0.2 1.9e-22 79.2 0.2 2.0 3 0 0 3 3 3 1 Ribosomal protein S15 SpoVIF PF14069.6 KLO20144.1 - 0.087 12.6 0.6 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Stage VI sporulation protein F HOIP-UBA PF16678.5 KLO20144.1 - 0.31 11.1 2.9 1.2 9.1 0.0 2.7 2 1 0 3 3 3 0 HOIP UBA domain pair UCH PF00443.29 KLO20145.1 - 9.4e-57 192.4 0.0 1.4e-56 191.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KLO20145.1 - 2.3e-31 109.6 0.1 3e-23 82.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KLO20145.1 - 0.059 12.8 2.5 0.24 10.8 1.4 2.4 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase MOSC PF03473.17 KLO20146.1 - 2e-26 92.6 0.0 3.3e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KLO20146.1 - 1.2e-17 63.9 0.0 1.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Rotamase PF00639.21 KLO20147.1 - 1.1e-20 74.4 0.0 1.4e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KLO20147.1 - 1.9e-20 73.5 0.0 2.5e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KLO20147.1 - 3.3e-09 36.7 2.1 1.1e-08 35.0 0.8 2.1 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KLO20147.1 - 0.00078 20.3 0.0 0.0012 19.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Sel1 PF08238.12 KLO20148.1 - 2e-44 149.0 29.6 1.6e-08 34.9 0.2 8.1 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 KLO20148.1 - 0.18 12.5 5.8 19 6.2 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.17 KLO20149.1 - 1.1e-77 260.4 0.0 1.8e-77 259.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KLO20149.1 - 1.6e-46 157.4 0.3 9.4e-46 154.9 0.0 2.4 3 0 0 3 3 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KLO20149.1 - 7.3e-34 116.1 0.0 1.4e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KLO20149.1 - 1.2e-14 53.8 1.9 3.3e-14 52.5 1.9 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KLO20149.1 - 2e-13 50.4 0.0 4.3e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KLO20149.1 - 7.3e-10 38.7 0.0 5.2e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KLO20149.1 - 3.3e-05 23.6 0.2 0.0093 15.8 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KLO20149.1 - 5.2e-05 23.3 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KLO20149.1 - 0.00011 22.8 0.7 0.37 11.5 0.0 2.5 2 0 0 2 2 2 2 HlyD family secretion protein RimK PF08443.11 KLO20149.1 - 0.00033 20.3 0.0 0.001 18.7 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.19 KLO20149.1 - 0.0039 17.0 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_D23 PF16576.5 KLO20149.1 - 0.03 13.5 0.7 0.95 8.6 0.0 2.2 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Ntox43 PF15537.6 KLO20149.1 - 0.054 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial toxin 43 ATP-grasp_4 PF13535.6 KLO20149.1 - 0.12 12.0 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain DUF768 PF05589.11 KLO20149.1 - 0.21 11.6 0.3 5.7 7.0 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF768) GDP_Man_Dehyd PF16363.5 KLO20150.1 - 4.2e-41 141.4 0.0 5.1e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KLO20150.1 - 3.5e-38 131.4 0.0 4.3e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO20150.1 - 6.6e-10 38.5 0.0 2e-09 36.9 0.0 1.8 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KLO20150.1 - 2.9e-08 33.2 0.0 4.4e-07 29.3 0.0 2.4 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KLO20150.1 - 5.2e-07 29.1 0.0 2.7e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KLO20150.1 - 3.1e-06 26.5 0.0 1.3e-05 24.5 0.0 1.9 2 1 0 2 2 2 1 Male sterility protein KR PF08659.10 KLO20150.1 - 4.6e-06 26.7 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KLO20150.1 - 0.023 14.2 0.0 0.33 10.4 0.0 2.2 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 KLO20150.1 - 0.098 12.5 0.0 1.5 8.7 0.0 2.1 1 1 0 1 1 1 0 NAD(P)H-binding 4HBT PF03061.22 KLO20151.1 - 8.9e-13 48.4 0.5 4.2e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily 4HBT_3 PF13622.6 KLO20151.1 - 3.2e-06 27.6 2.2 0.012 15.9 0.2 2.1 2 0 0 2 2 2 2 Thioesterase-like superfamily PheRS_DBD3 PF18553.1 KLO20151.1 - 0.015 15.6 0.1 0.034 14.4 0.1 1.6 1 0 0 1 1 1 0 PheRS DNA binding domain 3 Big_3_5 PF16640.5 KLO20152.1 - 0.065 13.4 7.0 0.45 10.7 0.9 3.8 2 1 1 3 3 3 0 Bacterial Ig-like domain (group 3) efThoc1 PF11957.8 KLO20154.1 - 2.8e-100 336.3 6.2 2.5e-95 320.0 3.9 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Nucleo_P87 PF07267.11 KLO20154.1 - 0.098 11.5 4.1 0.12 11.2 2.8 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pkinase PF00069.25 KLO20155.1 - 8.6e-65 218.7 0.0 1.1e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO20155.1 - 1.7e-30 106.2 0.0 2.4e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KLO20155.1 - 2.7e-06 26.6 0.0 6.4e-06 25.3 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KLO20155.1 - 8e-05 22.1 0.1 0.00023 20.6 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO20155.1 - 0.00013 22.0 0.3 0.00051 20.0 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO20155.1 - 0.003 16.9 0.0 0.0043 16.4 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KLO20155.1 - 0.066 12.2 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 KLO20155.1 - 0.076 12.6 0.0 0.17 11.5 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Cortexin PF11057.8 KLO20156.1 - 0.11 12.4 0.6 0.21 11.4 0.6 1.5 1 0 0 1 1 1 0 Cortexin of kidney UPF0731 PF14982.6 KLO20156.1 - 0.15 12.2 0.4 0.55 10.5 0.1 2.0 2 0 0 2 2 2 0 UPF0731 family DUF4083 PF13314.6 KLO20156.1 - 1.8 8.6 8.7 0.12 12.4 2.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4083) Peroxidase_2 PF01328.17 KLO20157.1 - 1.1e-44 153.2 0.0 3.3e-44 151.7 0.0 1.6 1 1 0 1 1 1 1 Peroxidase, family 2 Exo84_C PF16528.5 KLO20158.1 - 6.1e-41 140.5 2.0 6.1e-41 140.5 2.0 1.8 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KLO20158.1 - 8.2e-17 61.1 0.9 2.6e-16 59.5 0.9 1.9 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 KLO20158.1 - 8.5e-06 25.9 0.6 2e-05 24.7 0.6 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 L27_2 PF09045.10 KLO20158.1 - 0.00032 20.6 0.1 0.35 10.8 0.0 2.7 2 0 0 2 2 2 2 L27_2 BLACT_WH PF17778.1 KLO20159.1 - 5.5e-18 64.7 0.3 1.5e-17 63.3 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KLO20159.1 - 5e-17 62.6 1.1 5.3e-09 36.4 0.1 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KLO20159.1 - 2.4e-05 24.0 0.9 7.3e-05 22.4 0.9 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Stork_head PF10264.9 KLO20159.1 - 0.026 14.7 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain DNA_methylase PF00145.17 KLO20160.1 - 2.9e-35 122.2 0.0 1.8e-33 116.3 0.0 2.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KLO20160.1 - 2.6e-18 66.1 0.0 2e-12 47.0 0.0 2.7 2 0 0 2 2 2 2 BAH domain Met_10 PF02475.16 KLO20160.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Dus PF01207.17 KLO20161.1 - 1.4e-52 178.7 0.0 2.7e-52 177.8 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) ADH_zinc_N PF00107.26 KLO20162.1 - 7.9e-11 42.1 0.4 1.6e-10 41.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KLO20162.1 - 1.8e-06 27.8 0.0 3.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KLO20162.1 - 0.012 16.7 0.0 0.02 15.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase PF00069.25 KLO20163.1 - 1.7e-67 227.6 0.0 2e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO20163.1 - 1.1e-31 110.1 0.0 1.4e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KLO20163.1 - 2e-05 23.7 0.0 2.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KLO20163.1 - 0.00075 18.9 0.1 0.0019 17.6 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KLO20163.1 - 0.00076 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KLO20163.1 - 0.0015 18.0 0.0 0.036 13.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 KLO20163.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KLO20163.1 - 0.027 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Abhydrolase_3 PF07859.13 KLO20164.1 - 2.4e-35 122.3 0.0 3.1e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KLO20164.1 - 5.9e-07 29.2 0.0 2.5e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KLO20164.1 - 3.1e-06 26.8 0.0 5.7e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KLO20164.1 - 0.0072 16.9 0.7 0.13 12.9 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KLO20164.1 - 0.0085 15.7 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 KLO20164.1 - 0.032 14.0 0.1 0.067 13.0 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KLO20164.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Amidohydro_1 PF01979.20 KLO20165.1 - 2.2e-11 43.7 0.0 5.3e-08 32.6 0.0 3.2 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.11 KLO20165.1 - 5.3e-11 42.7 0.3 0.00012 21.7 0.0 3.6 4 0 0 4 4 4 2 Amidohydrolase family DUF2235 PF09994.9 KLO20166.1 - 3.6e-92 308.8 0.1 4.7e-92 308.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) E1_DerP2_DerF2 PF02221.15 KLO20167.1 - 1e-27 97.2 0.8 1.2e-27 97.0 0.8 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 KLO20167.1 - 5.5e-05 23.5 0.1 9.9e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 ML-like domain DUF2271 PF10029.9 KLO20167.1 - 0.045 13.4 0.1 0.54 9.9 0.0 2.0 1 1 1 2 2 2 0 Predicted periplasmic protein (DUF2271) DUF1091 PF06477.13 KLO20167.1 - 0.065 13.7 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) Enolase_C PF00113.22 KLO20167.1 - 0.086 12.1 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain Tetraspanin PF00335.20 KLO20168.1 - 0.1 12.3 10.9 0.1 12.3 10.0 1.4 1 1 0 1 1 1 0 Tetraspanin family Glyco_hydro_88 PF07470.13 KLO20169.1 - 6.8e-32 110.9 0.0 8.1e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Cellulase PF00150.18 KLO20170.1 - 1.2e-22 80.6 0.4 1.6e-22 80.3 0.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KLO20170.1 - 0.00084 19.1 0.5 0.0027 17.4 0.3 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 KLO20170.1 - 0.045 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase DUF2158 PF09926.9 KLO20170.1 - 0.091 12.5 0.3 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) EF-hand_7 PF13499.6 KLO20171.1 - 5.7e-21 74.8 9.1 5.3e-12 46.0 3.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KLO20171.1 - 1.4e-19 68.1 13.3 9e-08 31.1 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KLO20171.1 - 8.5e-16 56.5 12.0 4.6e-07 29.3 0.3 4.7 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KLO20171.1 - 1.1e-14 54.0 12.7 1.9e-08 34.0 1.4 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KLO20171.1 - 2.1e-05 24.4 4.8 0.0057 16.6 0.2 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KLO20171.1 - 4.1e-05 23.8 1.1 0.014 15.7 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KLO20171.1 - 0.0005 19.4 3.9 0.0039 16.6 0.8 3.5 4 1 1 5 5 5 2 EF hand SPARC_Ca_bdg PF10591.9 KLO20171.1 - 0.005 17.1 3.1 0.16 12.3 0.5 2.4 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region UBA_2 PF08587.11 KLO20171.1 - 0.049 13.8 0.0 18 5.6 0.0 2.6 2 1 0 2 2 2 0 Ubiquitin associated domain (UBA) PhetRS_B1 PF18262.1 KLO20171.1 - 0.085 13.1 0.9 0.23 11.7 0.9 1.8 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain TauD PF02668.16 KLO20172.1 - 9.3e-49 166.6 0.1 1.2e-48 166.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CorA PF01544.18 KLO20173.1 - 3.7e-31 108.5 5.2 8.3e-30 104.1 3.5 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 KLO20173.1 - 0.00028 19.8 0.2 0.00042 19.2 0.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF5360 PF17314.2 KLO20173.1 - 0.0066 16.5 1.5 0.011 15.8 1.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5360) MGAT2 PF05060.14 KLO20173.1 - 0.073 12.1 0.8 0.1 11.6 0.1 1.5 2 0 0 2 2 2 0 N-acetylglucosaminyltransferase II (MGAT2) CorA PF01544.18 KLO20174.1 - 4e-31 108.4 4.6 7.6e-29 100.9 2.8 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF5360 PF17314.2 KLO20174.1 - 0.018 15.1 1.3 0.032 14.3 1.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5360) CorA PF01544.18 KLO20175.1 - 8e-33 114.0 0.4 1.7e-28 99.8 0.2 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF5360 PF17314.2 KLO20175.1 - 0.023 14.8 2.7 0.039 14.0 2.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5360) p450 PF00067.22 KLO20176.1 - 8.6e-70 235.8 0.0 1.1e-69 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KLO20177.1 - 2.8e-64 217.6 0.0 6.9e-57 193.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 DUF2156 PF09924.9 KLO20178.1 - 6.6e-23 81.2 0.0 7.5e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Cellulase PF00150.18 KLO20179.1 - 1e-13 51.4 0.0 2.1e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1515 PF07439.11 KLO20180.1 - 0.45 10.6 2.4 0.87 9.6 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Hydin_ADK PF17213.3 KLO20180.1 - 2.2 8.5 6.7 15 5.8 0.5 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Glyco_transf_17 PF04724.13 KLO20181.1 - 5.1e-88 295.5 0.0 7e-88 295.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 Lum_binding PF00677.17 KLO20182.1 - 7.2e-43 144.5 0.5 6.7e-21 74.1 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain Polyketide_cyc2 PF10604.9 KLO20182.1 - 0.008 16.5 2.2 0.087 13.1 0.2 2.2 1 1 1 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport CRAL_TRIO PF00650.20 KLO20184.1 - 7.5e-37 126.5 0.0 1e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KLO20184.1 - 8.6e-06 25.8 0.6 1.6e-05 25.0 0.6 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KLO20184.1 - 0.003 17.7 0.0 0.0055 16.9 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain polyprenyl_synt PF00348.17 KLO20185.1 - 2.1e-60 204.0 0.0 6.4e-55 186.0 0.0 2.0 2 0 0 2 2 2 2 Polyprenyl synthetase polyprenyl_synt PF00348.17 KLO20186.1 - 2.4e-58 197.2 0.0 5.3e-53 179.7 0.0 2.0 2 0 0 2 2 2 2 Polyprenyl synthetase RasGEF PF00617.19 KLO20188.1 - 3.3e-43 147.9 0.1 5.4e-43 147.2 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KLO20188.1 - 5.8e-18 65.1 0.0 1.2e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KLO20188.1 - 2.6e-13 49.3 0.2 6.7e-13 48.0 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KLO20188.1 - 7e-10 38.4 0.0 5.6e-09 35.5 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain SH3_9 PF14604.6 KLO20188.1 - 7.8e-07 28.9 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ras PF00071.22 KLO20189.1 - 2.4e-55 186.5 0.3 2.8e-55 186.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO20189.1 - 3.7e-35 120.7 0.1 5.2e-35 120.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO20189.1 - 1.9e-14 53.5 0.0 2.2e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KLO20189.1 - 2.3e-06 27.1 0.0 2.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KLO20189.1 - 8.7e-06 25.8 0.0 1.6e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KLO20189.1 - 1.1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KLO20189.1 - 0.00017 21.5 0.1 0.21 11.5 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KLO20189.1 - 0.0087 16.5 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 KLO20189.1 - 0.021 14.0 0.3 0.23 10.6 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.15 KLO20189.1 - 0.052 13.5 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 NTPase Septin PF00735.18 KLO20189.1 - 0.11 11.8 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 KLO20189.1 - 0.17 12.2 0.0 1.9 8.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain RRM_1 PF00076.22 KLO20190.1 - 9.8e-12 44.5 0.1 4.6e-10 39.2 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bromodomain PF00439.25 KLO20191.1 - 5.9e-58 192.9 0.2 1.5e-20 73.0 0.1 3.5 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.20 KLO20191.1 - 3.5e-08 33.3 0.0 6.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KLO20191.1 - 0.013 15.7 0.1 0.037 14.2 0.0 1.7 2 0 0 2 2 2 0 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 KLO20191.1 - 0.15 12.5 0.9 2 8.8 0.0 3.1 4 0 0 4 4 4 0 HEAT repeats Methyltransf_23 PF13489.6 KLO20192.1 - 6e-09 35.9 0.0 1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO20192.1 - 6.2e-09 36.4 0.0 1.3e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KLO20192.1 - 1.5e-06 28.7 0.0 2.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO20192.1 - 1.8e-05 25.4 0.0 3.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KLO20192.1 - 0.00016 21.2 0.0 0.00027 20.5 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 KLO20192.1 - 0.00049 19.9 0.0 0.0049 16.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KLO20192.1 - 0.00087 18.6 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 KLO20192.1 - 0.0083 16.2 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KLO20192.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KLO20192.1 - 0.039 13.3 0.0 0.081 12.2 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KLO20192.1 - 0.044 13.2 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3246 PF11596.8 KLO20192.1 - 0.069 12.6 1.8 0.1 12.0 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Ist1 PF03398.14 KLO20193.1 - 1.5e-56 190.8 0.0 1.8e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway VASt PF16016.5 KLO20194.1 - 1.4e-38 132.7 0.1 3.1e-38 131.6 0.1 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KLO20194.1 - 1.1e-22 80.0 0.0 2.5e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Thioredoxin PF00085.20 KLO20195.1 - 1.9e-28 98.5 0.0 2.2e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KLO20195.1 - 1.1e-06 29.0 0.0 2.8e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KLO20195.1 - 2.1e-05 24.4 0.0 2.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KLO20195.1 - 6.1e-05 22.5 0.0 6.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KLO20195.1 - 0.00085 19.1 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KLO20195.1 - 0.0012 18.6 0.1 0.011 15.5 0.1 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_8 PF13905.6 KLO20195.1 - 0.0021 18.4 0.0 0.011 16.0 0.0 2.0 1 1 2 3 3 3 1 Thioredoxin-like Glutaredoxin PF00462.24 KLO20195.1 - 0.0056 16.9 0.0 0.012 15.8 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin Pyridox_oxase_2 PF12766.7 KLO20196.1 - 4.9e-26 91.3 0.0 7.8e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KLO20196.1 - 5.4e-06 26.5 0.0 9.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.25 KLO20198.1 - 4.5e-61 206.5 0.0 1.6e-60 204.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO20198.1 - 5.9e-27 94.6 0.0 3.6e-15 55.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KLO20198.1 - 2.5e-05 24.9 6.4 0.00022 21.8 4.8 3.6 2 0 0 2 2 2 1 Protein kinase C terminal domain PX PF00787.24 KLO20198.1 - 0.0013 18.7 0.1 0.029 14.3 0.0 3.0 3 0 0 3 3 3 1 PX domain FTA2 PF13095.6 KLO20198.1 - 0.0014 18.3 0.1 0.19 11.3 0.1 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KLO20198.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KLO20198.1 - 0.013 14.8 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KLO20198.1 - 0.018 15.0 0.6 3.8 7.4 0.1 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Fungal_trans PF04082.18 KLO20200.1 - 0.093 11.7 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain PPR_2 PF13041.6 KLO20201.1 - 1e-36 124.9 8.7 3.2e-11 43.3 0.1 8.2 6 3 4 10 10 10 7 PPR repeat family PPR_3 PF13812.6 KLO20201.1 - 2.3e-30 104.4 0.1 9.8e-12 44.8 0.0 6.8 5 2 1 7 7 7 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 KLO20201.1 - 1.1e-15 57.0 3.8 0.39 10.5 0.0 7.5 8 0 0 8 8 8 6 PPR repeat PPR PF01535.20 KLO20201.1 - 1.5e-14 53.1 17.9 0.0012 19.0 0.0 9.7 12 0 0 12 12 12 4 PPR repeat PPR_long PF17177.4 KLO20201.1 - 5.3e-14 52.1 0.5 1.2e-06 28.1 0.3 4.3 1 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP DASH_Dad3 PF08656.10 KLO20201.1 - 0.025 14.7 0.1 0.07 13.2 0.1 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 GCSF PF16647.5 KLO20201.1 - 0.036 13.9 0.0 9.2 6.1 0.0 2.8 3 0 0 3 3 3 0 Granulocyte colony-stimulating factor Band_7 PF01145.25 KLO20202.1 - 2.3e-24 86.4 0.0 4.2e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KLO20202.1 - 0.044 13.5 0.0 0.095 12.4 0.0 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family GhoS PF11080.8 KLO20202.1 - 0.11 12.5 0.1 0.3 11.1 0.1 1.8 1 0 0 1 1 1 0 Endoribonuclease GhoS GRIP PF01465.20 KLO20203.1 - 7.4e-16 57.8 1.5 2.3e-15 56.2 1.5 1.9 1 0 0 1 1 1 1 GRIP domain Filament PF00038.21 KLO20203.1 - 1.5 8.3 86.7 0.012 15.3 11.3 5.0 1 1 3 4 4 4 0 Intermediate filament protein Fez1 PF06818.15 KLO20203.1 - 3.9 7.9 92.3 2.1 8.8 32.1 5.0 2 2 2 4 4 4 0 Fez1 GTP_EFTU PF00009.27 KLO20204.1 - 4.5e-58 196.0 0.4 8.3e-58 195.1 0.4 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KLO20204.1 - 6e-27 94.2 0.0 1.2e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KLO20204.1 - 9.4e-19 67.6 1.8 2.6e-18 66.2 1.8 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KLO20204.1 - 2.6e-05 24.3 0.1 4.5e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO20204.1 - 0.0024 17.8 0.1 0.0057 16.6 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KLO20204.1 - 0.0025 17.4 1.0 0.0035 17.0 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KLO20204.1 - 0.012 15.3 0.4 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KLO20204.1 - 0.081 12.3 0.2 0.33 10.3 0.2 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Pex14_N PF04695.13 KLO20205.1 - 2.9e-18 67.0 5.8 2.9e-18 67.0 5.8 3.2 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IFT57 PF10498.9 KLO20205.1 - 0.00067 18.7 1.4 0.0012 17.9 1.4 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF3584 PF12128.8 KLO20205.1 - 0.024 12.2 9.0 0.032 11.8 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MCPsignal PF00015.21 KLO20205.1 - 0.028 14.2 7.1 0.093 12.5 7.1 1.8 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.12 KLO20205.1 - 0.039 14.4 5.9 0.14 12.6 0.3 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 KLO20205.1 - 0.044 13.8 8.6 0.088 12.8 8.6 1.4 1 0 0 1 1 1 0 Laminin Domain II Med9 PF07544.13 KLO20205.1 - 0.051 13.7 9.4 0.66 10.1 7.7 2.7 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 BORCS8 PF10167.9 KLO20205.1 - 0.06 13.3 3.0 0.13 12.2 3.0 1.6 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 Golgin_A5 PF09787.9 KLO20205.1 - 0.11 11.9 7.7 0.17 11.3 7.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 AAA_13 PF13166.6 KLO20205.1 - 0.12 11.0 4.8 0.16 10.5 4.8 1.1 1 0 0 1 1 1 0 AAA domain Baculo_p24 PF05073.12 KLO20205.1 - 0.14 12.0 0.9 0.25 11.1 0.9 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein DUF948 PF06103.11 KLO20205.1 - 0.17 12.2 1.1 2.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HOIP-UBA PF16678.5 KLO20205.1 - 0.23 11.5 5.2 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 HOIP UBA domain pair LMBR1 PF04791.16 KLO20205.1 - 0.28 10.0 0.1 0.36 9.7 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 KLO20205.1 - 0.29 10.4 3.0 0.42 9.8 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Tektin PF03148.14 KLO20205.1 - 0.35 9.6 12.2 1.3 7.7 12.2 1.7 1 1 0 1 1 1 0 Tektin family Phlebovirus_NSM PF07246.11 KLO20205.1 - 0.46 9.8 4.5 0.66 9.3 4.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M LXG PF04740.12 KLO20205.1 - 0.51 10.0 7.2 1.1 8.9 7.2 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily RasGAP_C PF03836.15 KLO20205.1 - 0.59 10.3 5.0 11 6.2 0.2 2.3 1 1 1 2 2 2 0 RasGAP C-terminus DUF1664 PF07889.12 KLO20205.1 - 0.93 9.5 9.1 0.65 10.0 6.7 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) DUF4164 PF13747.6 KLO20205.1 - 1 9.7 16.3 0.52 10.6 3.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) FapA PF03961.13 KLO20205.1 - 1 7.9 6.6 1.7 7.2 6.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 KLO20205.1 - 1.1 8.1 14.4 1.2 8.0 12.4 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein ING PF12998.7 KLO20205.1 - 2.1 9.0 6.9 1 10.0 2.6 2.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding UPF0242 PF06785.11 KLO20205.1 - 3.6 7.7 7.2 6.1 6.9 7.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HisKA_3 PF07730.13 KLO20205.1 - 7.4 7.2 7.9 20 5.8 0.5 3.1 1 1 1 2 2 2 0 Histidine kinase GCV_H PF01597.19 KLO20206.1 - 2.6e-42 143.5 0.2 3e-42 143.4 0.2 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KLO20206.1 - 0.00026 20.9 0.2 0.00042 20.2 0.2 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KLO20206.1 - 0.0005 19.8 0.2 0.0008 19.2 0.2 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme ESSS PF10183.9 KLO20207.1 - 1e-12 48.2 0.9 1.3e-12 47.8 0.8 1.3 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fructosamin_kin PF03881.14 KLO20209.1 - 4.3e-59 200.1 0.0 5e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KLO20209.1 - 2.1e-05 24.6 0.0 4.1e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO20210.1 - 7.3e-49 165.9 0.0 1.1e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KLO20210.1 - 2.3e-33 114.3 0.2 5.8e-33 113.0 0.1 1.8 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KLO20210.1 - 1.3e-10 41.6 0.2 0.00011 22.2 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KLO20210.1 - 1.4e-07 31.1 0.0 0.013 14.9 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family SMN PF06003.12 KLO20210.1 - 0.013 14.8 0.3 0.02 14.2 0.3 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) TUDOR PF00567.24 KLO20211.1 - 8.3e-06 25.8 0.0 3.1e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Tudor domain Relaxase PF03432.14 KLO20211.1 - 0.0032 17.1 3.2 0.0032 17.1 3.2 1.7 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain RicinB_lectin_2 PF14200.6 KLO20212.1 - 1.4e-07 32.1 0.7 0.003 18.3 0.0 2.7 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_25 PF01183.20 KLO20213.1 - 9e-46 156.3 0.1 1.1e-45 155.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Sel1 PF08238.12 KLO20214.1 - 1.6e-13 50.9 14.5 0.0005 20.7 0.2 6.3 6 0 0 6 6 6 4 Sel1 repeat TPR_2 PF07719.17 KLO20214.1 - 0.025 14.7 0.1 0.025 14.7 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KLO20214.1 - 0.26 11.6 1.1 6.3 7.3 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Nrap PF03813.14 KLO20216.1 - 0.18 11.8 0.0 0.19 11.8 0.0 1.1 1 0 0 1 1 1 0 Nrap protein domain 1 BTB PF00651.31 KLO20218.1 - 5.6e-05 23.3 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF2684 PF10885.8 KLO20218.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) IF4E PF01652.18 KLO20219.1 - 7.9e-51 172.0 0.0 9.9e-51 171.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TetR_C_21 PF17926.1 KLO20219.1 - 0.16 12.1 0.1 0.4 10.8 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Pil1 PF13805.6 KLO20220.1 - 1e-48 166.2 0.4 1.6e-48 165.5 0.4 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 FlxA PF14282.6 KLO20220.1 - 4.8 7.2 14.7 1.4 9.0 1.3 3.8 3 1 1 4 4 4 0 FlxA-like protein Mito_carr PF00153.27 KLO20221.1 - 1.4e-61 204.5 1.1 2.8e-19 68.8 0.5 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KLO20221.1 - 0.38 9.9 0.0 0.38 9.9 0.0 2.0 3 0 0 3 3 3 0 Gammaproteobacterial serine protease GYF PF02213.16 KLO20222.1 - 1.9e-14 53.1 0.2 4.2e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 GYF domain UreF PF01730.16 KLO20223.1 - 6.7e-28 97.9 0.1 1.2e-27 97.1 0.1 1.4 1 0 0 1 1 1 1 UreF Utp11 PF03998.13 KLO20224.1 - 9.4e-73 245.1 18.5 1.1e-72 244.9 18.5 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KLO20224.1 - 0.022 14.1 0.1 0.041 13.2 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 NPFF PF15085.6 KLO20224.1 - 0.1 12.9 2.7 0.28 11.6 2.7 1.7 1 0 0 1 1 1 0 Neuropeptide FF Glyco_hydro_16 PF00722.21 KLO20225.1 - 3.5e-07 29.9 0.1 2.8e-06 26.9 0.0 2.3 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 Arm PF00514.23 KLO20226.1 - 2.1e-70 230.8 30.3 1e-12 47.6 0.1 12.2 12 1 1 13 13 13 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KLO20226.1 - 1.3e-18 67.1 7.1 0.00092 19.7 0.3 8.0 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 KLO20226.1 - 1.4e-17 63.8 7.4 0.015 15.7 0.0 7.3 4 3 2 7 7 7 4 HEAT repeats HEAT PF02985.22 KLO20226.1 - 2.9e-14 51.9 10.9 0.49 10.8 0.0 9.4 9 0 0 9 9 9 4 HEAT repeat Arm_2 PF04826.13 KLO20226.1 - 8.6e-12 45.0 7.9 2.9e-08 33.5 2.1 2.3 1 1 1 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 KLO20226.1 - 3.5e-10 39.1 6.3 3.6e-07 29.1 0.1 2.9 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 KLO20226.1 - 3.1e-08 33.3 7.3 0.029 13.7 0.1 4.5 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.12 KLO20226.1 - 3.4e-08 32.1 2.5 4.9e-08 31.6 2.5 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Cnd1 PF12717.7 KLO20226.1 - 2e-05 24.7 8.5 0.0087 16.1 0.3 4.9 2 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KLO20226.1 - 0.00017 21.6 5.0 2.1 8.2 0.0 4.1 1 1 3 4 4 4 2 Domain of unknown function (DUF3361) HEAT_PBS PF03130.16 KLO20226.1 - 0.00073 20.0 5.9 59 4.8 0.1 7.4 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 KLO20226.1 - 0.0076 16.4 3.6 38 4.4 0.0 4.7 1 1 5 6 6 6 0 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 KLO20226.1 - 0.058 14.0 0.0 4.3 8.0 0.0 3.1 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 KLO20226.1 - 0.092 12.7 5.3 4.4 7.3 0.1 3.9 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 KLO20226.1 - 0.24 11.6 2.1 59 3.9 0.0 3.8 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 KLO20226.1 - 0.86 9.7 3.1 5 7.2 0.1 3.4 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain DKCLD PF08068.12 KLO20227.1 - 2e-33 114.2 0.1 2.1e-32 111.0 0.3 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KLO20227.1 - 9.1e-24 84.5 0.2 2.9e-16 60.2 0.1 3.5 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KLO20227.1 - 2.8e-22 78.6 1.1 5.8e-22 77.6 1.1 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KLO20227.1 - 1.1e-21 76.6 1.1 2.3e-21 75.5 1.1 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KLO20227.1 - 0.0071 16.6 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain Nucleo_P87 PF07267.11 KLO20227.1 - 4.6 6.0 12.8 6.3 5.5 12.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ribosomal_L22e PF01776.17 KLO20228.1 - 1.5e-43 147.6 0.1 1.8e-43 147.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family HA2 PF04408.23 KLO20229.1 - 3.9e-17 62.5 0.0 7.3e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KLO20229.1 - 3e-11 43.5 0.0 6.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KLO20230.1 - 3e-06 27.1 0.1 1.9e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KLO20230.1 - 5.3e-05 23.5 0.3 0.00059 20.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KLO20230.1 - 0.002 18.6 0.1 0.1 13.1 0.1 2.7 2 0 0 2 2 2 1 ABC transporter AAA_19 PF13245.6 KLO20230.1 - 0.022 15.1 0.0 0.054 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KLO20230.1 - 0.042 13.2 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 KLO20230.1 - 0.09 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 KLO20231.1 - 4e-66 223.1 0.8 7e-66 222.3 0.8 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KLO20231.1 - 3e-50 170.1 18.4 7.8e-50 168.7 18.4 1.8 1 0 0 1 1 1 1 DNA-binding domain Helicase_C PF00271.31 KLO20231.1 - 1.2e-16 61.1 0.0 2.7e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO20231.1 - 1.5e-07 31.6 0.0 3.9e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KLO20231.1 - 1.8e-05 24.0 1.3 6.1e-05 22.3 0.0 2.5 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Lyase_1 PF00206.20 KLO20232.1 - 3.1e-120 401.3 0.0 4.1e-120 400.9 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KLO20232.1 - 6.7e-19 68.0 0.0 1.4e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus PEX11 PF05648.14 KLO20233.1 - 1e-54 185.4 0.3 1.1e-54 185.2 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Thoc2 PF11732.8 KLO20233.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Cmc1 PF08583.10 KLO20234.1 - 5.1e-12 45.6 2.3 6e-12 45.4 2.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KLO20234.1 - 0.037 14.2 2.2 4.4 7.6 0.1 2.1 2 0 0 2 2 2 0 CHCH domain LIAS_N PF16881.5 KLO20235.1 - 1e-26 93.4 0.0 2.4e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KLO20235.1 - 1.6e-12 48.1 0.0 2.8e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Glyco_transf_8 PF01501.20 KLO20236.1 - 1.5e-19 70.6 0.1 2e-19 70.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KLO20236.1 - 0.0038 16.7 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Nucleotid_trans PF03407.16 KLO20236.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase ssDNA-exonuc_C PF10141.9 KLO20236.1 - 0.13 11.9 0.1 0.92 9.1 0.0 2.0 2 0 0 2 2 2 0 Single-strand DNA-specific exonuclease, C terminal domain Peptidase_M22 PF00814.25 KLO20237.1 - 1.7e-85 287.0 0.0 2e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KLO20237.1 - 0.043 13.5 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus EXOSC1 PF10447.9 KLO20238.1 - 9.3e-18 64.8 1.7 2.4e-12 47.4 0.2 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KLO20238.1 - 0.0019 18.0 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region 2-oxoacid_dh PF00198.23 KLO20239.1 - 1e-79 267.3 0.0 1.3e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KLO20239.1 - 2.3e-20 72.2 2.0 4.8e-20 71.2 1.2 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KLO20239.1 - 6.7e-16 58.4 0.2 1.7e-15 57.1 0.2 1.7 1 0 0 1 1 1 1 e3 binding domain Peptidase_S51 PF03575.17 KLO20239.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 Dr_adhesin PF12393.8 KLO20239.1 - 0.31 11.4 2.0 7.8 7.0 0.2 2.8 2 0 0 2 2 2 0 Dr family adhesin Peptidase_S21 PF00716.17 KLO20239.1 - 1.1 8.9 7.2 2.4 7.8 7.2 1.5 1 1 0 1 1 1 0 Assemblin (Peptidase family S21) Epimerase PF01370.21 KLO20240.1 - 4e-19 69.0 0.0 5.7e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KLO20240.1 - 1.7e-12 46.9 0.0 2.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KLO20240.1 - 1.6e-10 40.6 0.0 1.2e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KLO20240.1 - 5.8e-10 39.4 0.1 1.3e-09 38.2 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KLO20240.1 - 1.3e-06 28.0 0.1 3.6e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KLO20240.1 - 0.0025 17.3 0.1 0.0096 15.4 0.0 2.1 2 1 1 3 3 3 1 short chain dehydrogenase NmrA PF05368.13 KLO20240.1 - 0.0043 16.6 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.6 KLO20240.1 - 0.084 12.4 0.0 0.28 10.7 0.0 1.9 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Es2 PF09751.9 KLO20242.1 - 2.4e-86 291.2 9.8 3.1e-86 290.8 9.8 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 Nefa_Nip30_N PF10187.9 KLO20243.1 - 1.8e-26 92.5 10.1 1.8e-26 92.5 10.1 1.9 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 KLO20243.1 - 0.087 12.4 11.7 0.098 12.3 11.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rad51 PF08423.11 KLO20245.1 - 0.00029 20.2 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 Rad51 AAA_11 PF13086.6 KLO20245.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RecA PF00154.21 KLO20245.1 - 0.25 10.8 0.0 0.41 10.1 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein SLX9 PF15341.6 KLO20246.1 - 6.7e-20 71.8 6.7 9.6e-20 71.3 6.7 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 WD40_alt PF14077.6 KLO20247.1 - 0.12 12.3 1.6 4.4 7.2 0.0 3.3 3 0 0 3 3 3 0 Alternative WD40 repeat motif EamA PF00892.20 KLO20248.1 - 4.4e-14 52.8 29.3 2.2e-08 34.3 3.4 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 KLO20248.1 - 6.4e-10 39.0 10.7 1.9e-06 27.6 4.6 3.1 2 1 0 3 3 3 3 Solute carrier family 35 TPT PF03151.16 KLO20248.1 - 0.00076 18.9 9.4 0.0089 15.4 1.0 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF3955 PF13127.6 KLO20248.1 - 0.013 15.4 1.0 0.013 15.4 1.0 4.3 5 1 0 5 5 5 0 Protein of unknown function (DUF3955) Pho86 PF11124.8 KLO20248.1 - 6.3 6.2 6.9 1.5 8.2 0.8 2.1 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 TauD PF02668.16 KLO20249.1 - 7.1e-46 157.2 0.0 9.3e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KLO20249.1 - 6.2e-08 33.2 0.0 1.5e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KLO20249.1 - 0.0029 16.8 0.0 0.016 14.4 0.0 1.9 2 0 0 2 2 2 1 CsiD AMP-binding PF00501.28 KLO20250.1 - 2e-23 82.7 0.0 5.6e-21 74.6 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme GH3 PF03321.13 KLO20250.1 - 0.014 14.3 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter PPR_2 PF13041.6 KLO20252.1 - 1.8e-18 66.4 0.0 0.00013 22.1 0.0 6.9 7 1 0 7 7 7 3 PPR repeat family PPR_3 PF13812.6 KLO20252.1 - 1.7e-16 60.0 0.2 0.094 12.8 0.0 6.9 7 0 0 7 7 7 5 Pentatricopeptide repeat domain PPR PF01535.20 KLO20252.1 - 5.1e-11 42.0 0.0 7.7e-05 22.7 0.0 5.8 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.7 KLO20252.1 - 7.1e-07 28.8 0.0 0.017 14.8 0.0 4.5 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 KLO20252.1 - 5.8e-06 25.8 2.9 0.095 12.0 0.0 4.4 4 1 1 5 5 5 1 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KLO20252.1 - 0.016 16.0 5.7 0.13 13.1 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO20252.1 - 0.017 14.5 2.3 0.052 12.9 2.3 1.8 1 0 0 1 1 1 0 MalT-like TPR region Hap4_Hap_bind PF10297.9 KLO20253.1 - 7.6e-09 35.4 3.6 1.7e-08 34.3 3.6 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KLO20253.1 - 4.4e-07 29.9 20.9 0.0014 18.7 6.8 2.6 1 1 1 2 2 2 2 bZIP transcription factor NUDE_C PF04880.13 KLO20253.1 - 0.00078 20.0 7.6 0.00078 20.0 7.6 4.1 4 1 0 4 4 4 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 KLO20253.1 - 0.0097 16.3 9.9 0.021 15.2 9.9 1.5 1 0 0 1 1 1 1 Cell division protein ZapB HAUS-augmin3 PF14932.6 KLO20253.1 - 0.024 14.2 7.0 0.037 13.6 7.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 bZIP_2 PF07716.15 KLO20253.1 - 0.027 14.5 19.4 1 9.5 7.4 2.6 1 1 1 2 2 2 0 Basic region leucine zipper Myc-LZ PF02344.15 KLO20253.1 - 0.23 11.6 6.3 0.46 10.6 6.3 1.5 1 0 0 1 1 1 0 Myc leucine zipper domain DUF5320 PF17253.2 KLO20253.1 - 0.37 11.9 1.9 1.2 10.3 1.9 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5320) YabA PF06156.13 KLO20253.1 - 0.49 11.1 4.9 0.95 10.1 4.9 1.4 1 0 0 1 1 1 0 Initiation control protein YabA HALZ PF02183.18 KLO20253.1 - 1.6 9.0 9.7 0.11 12.8 4.4 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper eIF2A PF08662.11 KLO20254.1 - 3.2e-38 131.6 0.0 4.2e-21 75.7 0.0 4.0 3 2 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KLO20254.1 - 2.4e-07 30.4 0.0 6.8e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 KLO20254.1 - 0.00027 21.1 0.3 35 4.8 0.0 5.8 6 1 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KLO20254.1 - 0.00094 20.0 0.1 0.6 11.1 0.1 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Sugar_tr PF00083.24 KLO20255.1 - 5.6e-46 157.3 26.7 3.8e-43 148.0 26.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO20255.1 - 2.1e-16 59.8 39.0 9.6e-10 37.9 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KLO20255.1 - 0.00045 18.9 19.7 0.089 11.3 7.7 3.2 3 0 0 3 3 3 3 MFS/sugar transport protein YbjN PF10722.9 KLO20255.1 - 0.092 12.8 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator SLS PF14611.6 KLO20256.1 - 5e-16 59.2 0.1 1.1e-15 58.1 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Spb1_C PF07780.12 KLO20257.1 - 5.9e-79 264.6 21.7 5.9e-79 264.6 21.7 3.1 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KLO20257.1 - 5e-55 186.3 0.1 1.3e-54 185.0 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KLO20257.1 - 1.9e-49 167.7 4.5 1.9e-49 167.7 4.5 4.8 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) UPF0181 PF03701.14 KLO20257.1 - 0.0008 19.0 0.7 0.18 11.5 0.2 2.7 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0181) PAXNEB PF05625.11 KLO20258.1 - 2.4e-52 178.3 0.0 3.8e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein ATPase PF06745.13 KLO20258.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC Exo_endo_phos PF03372.23 KLO20260.1 - 4.6e-23 81.9 0.0 1.1e-22 80.7 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGEF PF00621.20 KLO20261.1 - 2.9e-20 73.3 0.0 4.3e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain HMG_box_2 PF09011.10 KLO20261.1 - 0.14 12.7 0.3 0.29 11.7 0.3 1.4 1 0 0 1 1 1 0 HMG-box domain ACP PF06857.11 KLO20261.1 - 0.18 12.0 0.1 0.41 10.9 0.1 1.6 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) Peptidase_M16_C PF05193.21 KLO20262.1 - 4.1e-11 43.2 0.0 5.5e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KLO20262.1 - 9.9e-11 41.8 0.1 4.7e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KLO20262.1 - 1.9 7.5 3.9 10 5.2 2.1 2.3 2 0 0 2 2 2 0 Peptidase M16C associated NUFIP1 PF10453.9 KLO20263.1 - 7.1e-18 64.2 0.2 1.3e-17 63.4 0.2 1.5 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF1644 PF07800.12 KLO20263.1 - 0.0092 16.1 1.5 0.011 15.9 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1644) Ribosomal_L13 PF00572.18 KLO20264.1 - 1e-12 48.4 0.1 9.7e-11 42.0 0.0 2.7 2 1 0 2 2 2 1 Ribosomal protein L13 Chlorosome_CsmC PF11098.8 KLO20264.1 - 0.18 11.8 0.0 2.3 8.2 0.0 2.0 2 0 0 2 2 2 0 Chlorosome envelope protein C RasGEF PF00617.19 KLO20265.1 - 9.4e-30 104.1 0.1 1.8e-29 103.2 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KLO20265.1 - 4.2e-11 43.0 0.0 1.2e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Viral_helicase1 PF01443.18 KLO20265.1 - 0.0099 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 KLO20265.1 - 0.015 15.2 0.1 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KLO20265.1 - 0.041 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KLO20265.1 - 0.042 14.2 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 KLO20265.1 - 0.16 11.3 0.1 0.32 10.3 0.0 1.5 2 0 0 2 2 2 0 Septin SurE PF01975.17 KLO20266.1 - 2.2e-49 167.9 0.0 4.6e-49 166.8 0.0 1.5 2 0 0 2 2 2 1 Survival protein SurE SSP160 PF06933.11 KLO20266.1 - 1.9 6.6 4.4 2.7 6.1 4.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CTV_P6 PF06706.11 KLO20269.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.3 3 0 0 3 3 3 0 Citrus tristeza virus 6-kDa protein DUF2518 PF10726.9 KLO20269.1 - 0.18 11.5 3.7 0.18 11.5 1.5 2.2 3 0 0 3 3 3 0 Protein of function (DUF2518) Actin PF00022.19 KLO20271.1 - 2.3e-124 415.1 0.0 1.2e-123 412.7 0.0 1.8 1 1 0 1 1 1 1 Actin Ribosomal_L15e PF00827.17 KLO20272.1 - 1.1e-90 302.5 10.4 1.3e-90 302.3 10.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_S24e PF01282.19 KLO20274.1 - 3.8e-33 113.3 0.0 3.8e-33 113.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S24e GPI2 PF06432.11 KLO20275.1 - 8.3e-87 291.2 14.2 9.4e-87 291.0 14.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Cyt_c_ox_IV PF12270.8 KLO20275.1 - 5.5 7.1 8.5 0.23 11.6 0.9 2.5 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV bZIP_1 PF00170.21 KLO20276.1 - 5.3e-06 26.4 4.0 1.3e-05 25.2 4.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor APG6_N PF17675.1 KLO20276.1 - 0.0011 19.5 3.3 0.0019 18.7 3.3 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region SlyX PF04102.12 KLO20276.1 - 0.0018 18.8 0.1 0.0018 18.8 0.1 2.1 2 0 0 2 2 1 1 SlyX Cast PF10174.9 KLO20276.1 - 0.0051 15.1 1.9 0.0074 14.6 1.9 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone TolA_bind_tri PF16331.5 KLO20276.1 - 0.0065 16.5 1.4 0.014 15.5 1.4 1.4 1 0 0 1 1 1 1 TolA binding protein trimerisation DUF148 PF02520.17 KLO20276.1 - 0.0065 16.6 0.4 0.011 15.9 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF148 Cnn_1N PF07989.11 KLO20276.1 - 0.017 15.2 0.6 0.034 14.3 0.6 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Rootletin PF15035.6 KLO20276.1 - 0.028 14.4 5.2 0.048 13.7 5.2 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion bZIP_2 PF07716.15 KLO20276.1 - 0.053 13.6 0.7 0.053 13.6 0.7 2.9 2 1 1 3 3 2 0 Basic region leucine zipper TPR_MLP1_2 PF07926.12 KLO20276.1 - 0.079 13.0 3.6 0.14 12.2 3.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein IKBKB_SDD PF18397.1 KLO20276.1 - 0.12 11.7 0.9 0.2 10.9 0.9 1.3 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain Cortex-I_coil PF09304.10 KLO20276.1 - 0.13 12.5 1.0 0.25 11.6 1.0 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil BST2 PF16716.5 KLO20276.1 - 0.13 12.9 3.2 0.24 12.0 3.2 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 TMF_TATA_bd PF12325.8 KLO20276.1 - 0.17 12.1 2.5 0.31 11.3 2.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 KLO20276.1 - 0.18 12.0 1.0 0.32 11.2 0.8 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family betaPIX_CC PF16523.5 KLO20276.1 - 0.18 11.6 0.3 0.31 10.9 0.3 1.3 1 0 0 1 1 1 0 betaPIX coiled coil YabA PF06156.13 KLO20276.1 - 0.25 12.0 0.9 0.46 11.2 0.9 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF812 PF05667.11 KLO20276.1 - 0.3 9.9 4.2 0.41 9.5 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ZapB PF06005.12 KLO20276.1 - 0.41 11.1 2.6 0.81 10.2 2.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapB ATG16 PF08614.11 KLO20276.1 - 2.3 8.4 15.0 0.09 13.0 8.2 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ANAPC4 PF12896.7 KLO20277.1 - 4.5e-38 130.8 0.0 8.7e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KLO20277.1 - 3.5e-05 24.0 0.0 7.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KLO20277.1 - 0.23 9.4 0.0 0.3 9.0 0.0 1.1 1 0 0 1 1 1 0 IKI3 family DEAD PF00270.29 KLO20278.1 - 8e-49 165.8 0.0 2.5e-48 164.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO20278.1 - 6.8e-28 97.2 0.0 9e-27 93.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain BUD22 PF09073.10 KLO20278.1 - 0.41 9.9 56.4 0.35 10.1 27.0 2.2 2 0 0 2 2 2 0 BUD22 DltD PF04914.12 KLO20278.1 - 6 6.2 9.6 3.8 6.8 7.7 1.6 1 1 0 1 1 1 0 DltD protein Phage_holin_Dp1 PF16938.5 KLO20279.1 - 0.055 13.7 0.4 0.055 13.7 0.4 1.9 2 0 0 2 2 2 0 Putative phage holin Dp-1 DPBB_1 PF03330.18 KLO20281.1 - 0.015 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Lytic transglycolase DEC-1_N PF04625.13 KLO20281.1 - 4.5 6.2 10.3 5.9 5.8 10.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SAD_SRA PF02182.17 KLO20282.1 - 1.7e-49 167.5 0.0 3.3e-49 166.6 0.0 1.5 1 0 0 1 1 1 1 SAD/SRA domain FAM176 PF14851.6 KLO20282.1 - 2.6 7.7 6.2 16 5.1 0.3 2.4 2 0 0 2 2 2 0 FAM176 family Mpp10 PF04006.12 KLO20284.1 - 2.2e-114 383.1 65.6 1.3e-113 380.6 65.4 2.1 1 1 1 2 2 2 1 Mpp10 protein Spt20 PF12090.8 KLO20284.1 - 0.4 10.2 0.0 0.4 10.2 0.0 2.7 3 0 0 3 3 3 0 Spt20 family Lyase_8 PF02278.18 KLO20285.1 - 3.2e-61 207.1 1.2 5.6e-61 206.3 1.0 1.6 1 1 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 KLO20285.1 - 1.4e-20 73.5 0.0 2.3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 KLO20285.1 - 0.00046 20.6 0.0 0.0013 19.1 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain DUF4501 PF14946.6 KLO20286.1 - 6.4 6.8 5.7 0.26 11.3 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) zf_UBZ PF18439.1 KLO20287.1 - 0.0047 16.5 0.2 0.0047 16.5 0.2 5.1 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 KLO20287.1 - 0.044 14.2 0.7 0.044 14.2 0.7 7.1 6 1 1 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO20287.1 - 0.099 13.5 45.8 3 8.9 5.1 7.3 7 0 0 7 7 7 0 C2H2-type zinc finger Ribosomal_S3_C PF00189.20 KLO20288.1 - 5.9e-25 87.6 0.1 5.5e-24 84.5 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KLO20288.1 - 1.1e-10 41.2 0.0 1.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 KH domain Amidase PF01425.21 KLO20289.1 - 3.3e-108 362.6 0.0 3.8e-108 362.3 0.0 1.0 1 0 0 1 1 1 1 Amidase Lipase3_N PF03893.16 KLO20290.1 - 0.085 12.9 0.3 0.19 11.8 0.3 1.6 1 0 0 1 1 1 0 Lipase 3 N-terminal region SprB PF13573.6 KLO20291.1 - 0.042 13.6 11.0 0.65 9.8 2.2 2.8 2 0 0 2 2 2 0 SprB repeat FAD_binding_4 PF01565.23 KLO20291.1 - 0.064 13.0 4.0 2.5 7.8 0.1 3.3 2 1 1 3 3 3 0 FAD binding domain Thiolase_N PF00108.23 KLO20292.1 - 6.7e-62 209.2 0.0 1.1e-61 208.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KLO20292.1 - 9.7e-42 141.5 0.9 2e-41 140.5 0.2 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KLO20292.1 - 0.058 13.0 0.2 0.23 11.0 0.1 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KLO20292.1 - 0.093 12.6 0.8 20 5.1 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glycolytic PF00274.19 KLO20293.1 - 2.3e-75 253.5 0.0 2.9e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Nexin_C PF08628.12 KLO20293.1 - 0.00085 19.9 0.0 0.0015 19.1 0.0 1.4 1 0 0 1 1 1 1 Sorting nexin C terminal Pectinesterase PF01095.19 KLO20294.1 - 2.1e-34 118.6 2.8 2.7e-34 118.3 2.8 1.1 1 0 0 1 1 1 1 Pectinesterase Ribosomal_L32p PF01783.23 KLO20295.1 - 1.2e-17 63.9 4.8 1.5e-17 63.6 4.8 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.6 KLO20295.1 - 0.0029 17.5 0.8 0.0046 16.9 0.8 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 GcpE PF04551.14 KLO20295.1 - 0.059 12.4 0.1 0.063 12.3 0.1 1.0 1 0 0 1 1 1 0 GcpE protein zf-ribbon_3 PF13248.6 KLO20295.1 - 0.65 9.5 5.6 1.4 8.5 5.6 1.6 1 1 0 1 1 1 0 zinc-ribbon domain ETC_C1_NDUFA5 PF04716.14 KLO20296.1 - 1.1e-24 86.1 0.1 1.7e-24 85.4 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region DSX_dimer PF08828.10 KLO20296.1 - 0.0057 16.3 0.2 0.01 15.5 0.2 1.4 1 0 0 1 1 1 1 Doublesex dimerisation domain APH PF01636.23 KLO20296.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family HABP4_PAI-RBP1 PF04774.15 KLO20297.1 - 7.1e-10 39.8 13.4 7.1e-10 39.8 13.4 3.5 2 2 1 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 KLO20297.1 - 0.023 15.6 2.7 0.023 15.6 2.7 4.9 4 2 0 4 4 4 0 Stm1 HALZ PF02183.18 KLO20299.1 - 0.012 15.8 1.0 5.2 7.4 0.1 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3419 PF11899.8 KLO20300.1 - 7.2e-135 450.1 0.0 1.1e-134 449.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KLO20300.1 - 1.5e-08 34.7 0.0 9.4e-07 28.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KLO20300.1 - 2.3e-06 28.2 0.0 5.3e-05 23.8 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KLO20300.1 - 0.00056 19.3 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KLO20300.1 - 0.0011 19.7 0.0 0.023 15.5 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_4 PF02390.17 KLO20300.1 - 0.0027 17.2 0.0 0.02 14.4 0.0 2.2 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_31 PF13847.6 KLO20300.1 - 0.22 11.3 0.0 0.52 10.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain KTI12 PF08433.10 KLO20303.1 - 3.8e-77 259.4 0.0 4.1e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KLO20303.1 - 2.1e-08 34.4 0.0 3.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Pam16 PF03656.13 KLO20304.1 - 3.5e-18 65.8 1.3 1.7e-17 63.6 1.3 1.9 1 1 0 1 1 1 1 Pam16 ATP-synt_C PF00137.21 KLO20305.1 - 7.7e-24 83.8 32.3 3.5e-15 56.1 11.0 2.5 3 0 0 3 3 3 2 ATP synthase subunit C HRG PF16954.5 KLO20305.1 - 0.06 13.8 0.4 0.06 13.8 0.4 3.6 5 0 0 5 5 5 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene G0-G1_switch_2 PF15103.6 KLO20305.1 - 0.082 13.3 0.5 1.2 9.6 0.1 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 Yippee-Mis18 PF03226.14 KLO20306.1 - 1.2e-13 51.2 0.1 1.4e-13 51.0 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SNF2_N PF00176.23 KLO20308.1 - 1.3e-61 208.3 0.5 2e-61 207.6 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 KLO20308.1 - 4.9e-24 84.6 0.1 1.7e-23 82.8 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Chromo PF00385.24 KLO20308.1 - 2.3e-20 72.2 2.0 4.2e-15 55.4 0.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KLO20308.1 - 1.8e-19 70.1 0.0 4.2e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KLO20308.1 - 4.2e-07 30.1 0.0 1.6e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 KLO20308.1 - 1.1e-06 29.0 1.0 1.1e-06 29.0 1.0 3.8 4 1 0 4 4 4 1 Chromodomain helicase DNA-binding domain 1 CDH1_2_SANT_HL1 PF18375.1 KLO20308.1 - 0.0042 17.7 2.5 0.011 16.4 0.2 2.9 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 CHDCT2 PF08074.11 KLO20308.1 - 0.011 16.0 0.2 0.25 11.5 0.0 3.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain DUF805 PF05656.14 KLO20309.1 - 0.034 14.5 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF805) LptF_LptG PF03739.14 KLO20309.1 - 0.053 12.4 0.1 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG zf-SNAP50_C PF12251.8 KLO20310.1 - 4.4e-31 108.1 0.0 7.2e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal TFIIA PF03153.13 KLO20313.1 - 2 8.4 12.4 5.5 6.9 12.4 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fib_alpha PF08702.10 KLO20314.1 - 0.013 15.7 5.8 0.013 15.7 5.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 KLO20314.1 - 0.052 14.0 1.5 13 6.4 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF812 PF05667.11 KLO20314.1 - 0.097 11.5 19.2 0.15 10.9 19.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TFIIA PF03153.13 KLO20314.1 - 0.17 11.9 21.4 0.3 11.0 21.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NIF PF03031.18 KLO20315.1 - 1.4e-54 184.1 0.1 1.6e-54 183.9 0.1 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KLO20315.1 - 0.0027 18.1 0.1 0.034 14.5 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase ATP-sulfurylase PF01747.17 KLO20316.1 - 4.3e-86 287.8 0.1 6e-86 287.3 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KLO20316.1 - 6.1e-55 185.2 0.0 1.1e-54 184.4 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 KLO20316.1 - 5.6e-52 175.8 0.0 8.2e-52 175.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase RPA43_OB PF17875.1 KLO20317.1 - 5.7e-26 91.6 0.0 5.7e-26 91.6 0.0 3.8 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KLO20317.1 - 2.1e-07 31.2 0.0 3.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 UPF0560 PF10577.9 KLO20317.1 - 0.025 13.1 0.0 0.025 13.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 DUF4629 PF15442.6 KLO20317.1 - 0.39 10.9 31.7 0.072 13.3 19.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) Tim54 PF11711.8 KLO20317.1 - 1.1 7.9 16.4 4.9 5.8 13.1 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.17 KLO20317.1 - 1.8 8.7 8.2 13 5.8 6.6 2.2 2 0 0 2 2 2 0 DDHD domain Herpes_DNAp_acc PF04929.12 KLO20317.1 - 7.7 5.4 10.7 14 4.5 10.7 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Arf PF00025.21 KLO20318.1 - 5.3e-37 126.9 0.0 1e-36 126.0 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KLO20318.1 - 1.6e-10 40.7 0.0 2.9e-05 23.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KLO20318.1 - 3e-07 30.7 0.0 6.9e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KLO20318.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KLO20318.1 - 0.00041 19.8 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KLO20318.1 - 0.00067 19.1 0.0 0.00095 18.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KLO20318.1 - 0.002 18.2 0.0 0.0049 16.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KLO20318.1 - 0.0055 16.3 0.0 0.036 13.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KLO20318.1 - 0.0089 16.3 0.0 0.027 14.7 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KLO20318.1 - 0.023 14.4 0.1 0.05 13.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KLO20318.1 - 0.055 14.0 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.17 KLO20318.1 - 0.057 13.1 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 Thymidylate kinase Octopine_DH PF02317.17 KLO20318.1 - 0.06 13.4 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain SRP54 PF00448.22 KLO20318.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DLIC PF05783.11 KLO20318.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_29 PF13555.6 KLO20318.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KLO20318.1 - 0.14 12.6 0.3 0.97 9.8 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KLO20318.1 - 0.14 12.6 0.1 0.24 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 KLO20319.1 - 1.8e-37 128.7 0.0 3.1e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO20319.1 - 9.3e-32 110.4 0.1 1.3e-31 109.9 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO20319.1 - 6.4e-08 32.7 0.4 2e-06 27.9 0.4 2.1 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 KLO20319.1 - 0.67 10.0 2.8 1.2 9.2 1.6 2.0 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Voltage_CLC PF00654.20 KLO20320.1 - 8.4e-91 304.8 34.3 8.4e-91 304.8 34.3 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KLO20320.1 - 4e-11 43.2 0.2 1.5e-05 25.4 0.0 3.3 4 0 0 4 4 4 2 CBS domain F-box-like PF12937.7 KLO20321.1 - 0.0017 18.2 1.1 0.0039 17.0 0.0 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KLO20321.1 - 0.0017 18.2 0.1 0.011 15.5 0.0 2.4 2 0 0 2 2 2 1 F-box domain PIG-U PF06728.13 KLO20322.1 - 2.4e-99 333.0 23.7 2.7e-99 332.8 23.7 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Hydrophobin PF01185.18 KLO20323.1 - 3.3e-17 62.9 8.6 4e-17 62.6 8.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Lipase PF00151.19 KLO20323.1 - 0.062 12.6 0.0 0.071 12.4 0.0 1.0 1 0 0 1 1 1 0 Lipase Hydrophobin PF01185.18 KLO20324.1 - 4.3e-20 72.1 9.5 5e-20 71.9 9.5 1.0 1 0 0 1 1 1 1 Fungal hydrophobin CPSase_sm_chain PF00988.22 KLO20325.1 - 2.8e-44 150.0 0.0 4.4e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KLO20325.1 - 2.4e-35 122.0 0.0 3.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KLO20325.1 - 2.1e-07 30.9 0.1 8.8e-06 25.6 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 bMG10 PF17973.1 KLO20325.1 - 0.046 13.9 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain DJ-1_PfpI PF01965.24 KLO20325.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family zf-LYAR PF08790.11 KLO20327.1 - 2.2e-14 53.0 0.4 4.1e-14 52.2 0.4 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger FtsH_ext PF06480.15 KLO20328.1 - 0.065 13.6 0.5 0.14 12.5 0.5 1.6 1 0 0 1 1 1 0 FtsH Extracellular Autophagy_N PF03986.13 KLO20329.1 - 1.8e-41 141.3 0.2 4.7e-41 139.9 0.0 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KLO20329.1 - 1.5e-15 57.5 0.2 2.9e-15 56.6 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KLO20329.1 - 1.9e-12 46.4 2.6 4e-12 45.4 2.6 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal SNARE_assoc PF09335.11 KLO20331.1 - 0.0034 17.8 0.0 0.0034 17.8 0.0 1.0 1 0 0 1 1 1 1 SNARE associated Golgi protein NADH_B2 PF14813.6 KLO20331.1 - 0.018 14.8 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Fungal_trans PF04082.18 KLO20332.1 - 1.6e-12 47.1 0.1 3e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KLO20332.1 - 4.2e-05 23.6 9.6 9.4e-05 22.5 9.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_63 PF03200.16 KLO20333.1 - 3e-07 29.6 8.6 1.9e-05 23.6 1.7 3.9 3 1 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain adh_short PF00106.25 KLO20334.1 - 4.5e-29 101.3 0.0 5.7e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO20334.1 - 1.6e-14 54.1 0.0 2.3e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KLO20334.1 - 8.2e-08 32.4 0.1 1.5e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 KLO20334.1 - 0.00056 20.3 0.0 0.0012 19.3 0.0 1.5 1 1 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KLO20334.1 - 0.0039 16.5 0.0 0.0082 15.5 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PALP PF00291.25 KLO20334.1 - 0.0045 16.4 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 3HCDH_N PF02737.18 KLO20334.1 - 0.0092 15.9 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HAUS-augmin3 PF14932.6 KLO20334.1 - 0.018 14.6 0.4 0.027 14.1 0.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ADH_zinc_N PF00107.26 KLO20334.1 - 0.047 13.7 0.2 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 KLO20334.1 - 0.083 13.0 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Helicase_RecD PF05127.14 KLO20334.1 - 0.1 12.4 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Helicase F420_oxidored PF03807.17 KLO20334.1 - 0.12 13.0 0.3 0.34 11.5 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 KLO20334.1 - 0.12 11.6 0.2 0.32 10.2 0.3 1.6 2 0 0 2 2 2 0 FAD binding domain NUDE_C PF04880.13 KLO20335.1 - 4.4 7.8 12.2 6 7.3 12.2 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PX PF00787.24 KLO20336.1 - 1.8e-15 56.9 0.0 2.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 PX domain Smr PF01713.21 KLO20337.1 - 1e-09 38.6 0.5 2.8e-09 37.2 0.5 1.8 1 0 0 1 1 1 1 Smr domain RCC1 PF00415.18 KLO20338.1 - 6.6e-63 209.2 13.0 5.5e-11 42.9 0.0 8.2 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KLO20338.1 - 3e-37 125.7 37.5 1.1e-08 34.6 0.1 7.5 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 KLO20338.1 - 0.012 15.4 0.0 3.9 7.2 0.0 3.2 3 0 0 3 3 3 0 TUP1-like enhancer of split SUKH-3 PF14433.6 KLO20338.1 - 0.095 13.2 0.6 29 5.1 0.0 4.2 5 0 0 5 5 5 0 SUKH-3 immunity protein GAPT PF11770.8 KLO20339.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Glyco_hydro_92 PF07971.12 KLO20341.1 - 1.7e-119 399.8 0.3 2.1e-119 399.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KLO20341.1 - 1.1e-50 172.8 0.0 2e-50 172.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Pept_tRNA_hydro PF01195.19 KLO20342.1 - 1.4e-24 87.0 0.0 1.7e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DPM3 PF08285.11 KLO20343.1 - 2.5e-32 110.9 0.1 2.8e-32 110.8 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HlyIII PF03006.20 KLO20344.1 - 1.3e-36 126.4 18.9 1.8e-36 126.0 18.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related Rubredoxin PF00301.20 KLO20345.1 - 0.019 15.0 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Rubredoxin Nudc_N PF14050.6 KLO20347.1 - 0.0052 16.7 0.0 0.0098 15.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. FAM212 PF15342.6 KLO20347.1 - 0.027 14.3 0.1 0.069 13.0 0.1 1.7 1 0 0 1 1 1 0 FAM212 family Rubredoxin PF00301.20 KLO20347.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Rubredoxin Nudc_N PF14050.6 KLO20349.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. Ribosomal_S8e PF01201.22 KLO20350.1 - 1.7e-56 190.2 0.6 2.2e-56 189.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e CagY_I PF14585.6 KLO20350.1 - 0.1 12.7 0.2 0.16 12.1 0.2 1.3 1 0 0 1 1 1 0 CagY type 1 repeat Glyco_transf_90 PF05686.12 KLO20351.1 - 2.7e-19 69.4 0.2 2.7e-19 69.4 0.2 2.0 3 0 0 3 3 3 1 Glycosyl transferase family 90 dCMP_cyt_deam_1 PF00383.23 KLO20352.1 - 2.2e-18 66.0 1.6 2.8e-18 65.6 1.6 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KLO20352.1 - 1.5e-11 44.6 3.6 2.7e-10 40.6 0.6 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.6 KLO20352.1 - 0.0023 18.0 0.1 0.0034 17.5 0.1 1.2 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase LmjF365940-deam PF14421.6 KLO20352.1 - 0.027 14.1 4.3 0.04 13.5 0.2 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases UDPGP PF01704.18 KLO20353.1 - 2.6e-198 658.8 1.5 3e-198 658.5 1.5 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Metallophos PF00149.28 KLO20354.1 - 3.2e-14 53.9 0.0 4e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KLO20354.1 - 0.0069 16.6 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BSD PF03909.17 KLO20355.1 - 1.5e-10 40.9 0.2 4.3e-10 39.4 0.2 1.9 1 0 0 1 1 1 1 BSD domain DUF883 PF05957.13 KLO20355.1 - 0.011 16.4 0.5 0.25 12.0 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) KfrA_N PF11740.8 KLO20355.1 - 0.012 16.3 2.1 0.035 14.8 1.0 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term COMMD1_N PF17221.3 KLO20355.1 - 0.11 12.8 0.3 0.88 9.9 0.0 2.4 2 0 0 2 2 2 0 COMMD1 N-terminal domain Amidohydro_1 PF01979.20 KLO20356.1 - 1.7e-49 169.0 0.0 2.7e-49 168.3 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KLO20356.1 - 6.6e-07 29.1 0.0 0.00034 20.2 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family UDPGP PF01704.18 KLO20357.1 - 2e-198 659.2 0.1 2.2e-198 659.0 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PAP_central PF04928.17 KLO20357.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Poly(A) polymerase central domain SET PF00856.28 KLO20358.1 - 6.1e-12 46.3 0.0 1.1e-11 45.4 0.0 1.5 1 1 0 1 1 1 1 SET domain adh_short_C2 PF13561.6 KLO20361.1 - 4.9e-49 167.0 0.1 1.6e-26 93.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KLO20361.1 - 2.1e-35 121.9 0.1 5.2e-23 81.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KLO20361.1 - 4e-08 33.4 0.0 1e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 KR domain Methyltransf_25 PF13649.6 KLO20361.1 - 0.052 14.2 0.0 0.14 12.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Cpn60_TCP1 PF00118.24 KLO20363.1 - 1.4e-161 538.5 0.3 1.7e-161 538.2 0.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FKBP_C PF00254.28 KLO20364.1 - 1.9e-28 98.6 0.0 4.5e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KLO20364.1 - 2.1e-21 76.5 0.0 2.1e-21 76.5 0.0 2.4 2 1 0 2 2 2 1 Nucleoplasmin-like domain Presenilin PF01080.17 KLO20364.1 - 0.43 9.3 8.4 0.54 9.0 8.4 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 KLO20364.1 - 6.6 4.8 32.9 11 4.1 32.9 1.4 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 KLO20364.1 - 9.4 4.2 8.5 12 3.9 8.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ARPC4 PF05856.12 KLO20365.1 - 4.4e-77 257.4 5.0 4.9e-77 257.2 5.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) TPR_12 PF13424.6 KLO20366.1 - 9.2e-10 38.7 10.9 7.9e-06 26.1 1.8 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-MYND PF01753.18 KLO20366.1 - 2.3e-09 37.2 17.2 5.4e-09 36.0 17.2 1.7 1 1 0 1 1 1 1 MYND finger TPR_10 PF13374.6 KLO20366.1 - 3e-05 23.7 9.0 0.00047 19.9 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KLO20366.1 - 0.0021 18.5 5.6 0.0042 17.6 1.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KLO20366.1 - 0.003 17.3 0.1 0.0091 15.8 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KLO20366.1 - 0.0039 17.9 7.3 0.026 15.3 0.2 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KLO20366.1 - 0.0039 16.6 0.9 0.0046 16.4 0.9 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 KLO20366.1 - 0.0049 17.0 0.2 0.031 14.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KLO20366.1 - 0.0084 16.1 3.3 0.35 11.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KLO20366.1 - 0.016 15.3 0.2 0.016 15.3 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KLO20366.1 - 0.035 13.8 0.7 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 TPR repeat TPR_21 PF09976.9 KLO20366.1 - 0.038 13.7 1.0 0.038 13.7 1.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 KLO20366.1 - 0.09 13.4 11.2 0.12 13.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KLO20366.1 - 1.2 9.9 9.7 0.076 13.7 1.9 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat SNF2_N PF00176.23 KLO20367.1 - 1.8e-68 230.9 0.0 1.8e-68 230.9 0.0 1.8 3 0 0 3 3 3 1 SNF2 family N-terminal domain HIRAN PF08797.11 KLO20367.1 - 8.6e-22 76.9 0.0 2.2e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.18 KLO20367.1 - 2.3e-14 54.0 0.1 9.8e-14 52.0 0.0 2.2 2 0 0 2 2 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.31 KLO20367.1 - 1.7e-13 50.9 0.0 4.6e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KLO20367.1 - 7.4e-08 32.1 6.6 1.6e-07 31.1 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KLO20367.1 - 9e-08 32.3 0.0 2.1e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KLO20367.1 - 2.8e-07 30.3 7.2 5.5e-07 29.4 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KLO20367.1 - 7.6e-07 28.9 4.6 1.4e-06 28.1 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KLO20367.1 - 5.5e-06 26.6 6.5 1.1e-05 25.6 6.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KLO20367.1 - 6.5e-06 26.0 4.0 1.3e-05 25.0 4.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KLO20367.1 - 1.4e-05 25.0 9.7 3.1e-05 23.9 9.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KLO20367.1 - 0.0011 19.2 4.5 0.0068 16.7 4.5 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain DEAD PF00270.29 KLO20367.1 - 0.0018 18.1 0.1 0.0057 16.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.6 KLO20367.1 - 0.0024 18.0 8.0 0.005 17.0 8.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KLO20367.1 - 0.0072 16.2 5.2 0.023 14.6 5.4 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KLO20367.1 - 0.22 11.4 2.2 0.59 10.0 2.2 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 KLO20367.1 - 1.7 8.5 7.7 4.2 7.2 7.7 1.7 1 0 0 1 1 1 0 RING-like zinc finger HMG_box PF00505.19 KLO20368.1 - 4.5e-13 49.4 2.7 4.5e-13 49.4 2.7 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO20368.1 - 4.2e-05 24.1 1.2 4.2e-05 24.1 1.2 2.1 2 0 0 2 2 2 1 HMG-box domain Ctr PF04145.15 KLO20369.1 - 2.9e-37 128.6 0.1 3.4e-37 128.3 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF3421 PF11901.8 KLO20370.1 - 2.1e-30 105.1 0.1 3.8e-24 84.9 0.0 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) RPA_interact_C PF14768.6 KLO20372.1 - 0.00039 20.9 0.3 0.00077 20.0 0.2 1.5 2 0 0 2 2 2 1 Replication protein A interacting C-terminal Apq12 PF12716.7 KLO20373.1 - 0.0091 15.9 1.7 0.0091 15.9 1.7 1.6 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis MPC PF03650.13 KLO20374.1 - 1.2e-39 134.8 1.0 1.4e-39 134.6 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Palm_thioest PF02089.15 KLO20375.1 - 1.2e-82 277.4 0.0 1.4e-82 277.2 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KLO20375.1 - 0.034 13.8 0.2 0.08 12.6 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Sugar_tr PF00083.24 KLO20378.1 - 4.7e-95 319.1 20.5 5.6e-95 318.8 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KLO20378.1 - 1.5e-18 66.9 25.9 1.5e-18 66.9 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase_Tyr PF07714.17 KLO20379.1 - 4.9e-23 81.7 0.0 5.5e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO20379.1 - 1.4e-22 80.3 0.0 1.8e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KLO20379.1 - 0.00032 19.6 0.1 0.00032 19.6 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO20379.1 - 0.00032 20.1 0.0 0.00047 19.6 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KLO20379.1 - 0.00051 20.0 0.0 0.0006 19.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KLO20379.1 - 0.034 13.8 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KLO20379.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.3 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase ALS_ss_C PF10369.9 KLO20380.1 - 8.7e-19 67.5 0.1 2.6e-17 62.8 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KLO20380.1 - 1.6e-13 50.2 0.1 3.6e-13 49.0 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KLO20380.1 - 6.4e-07 29.1 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 ACT domain Pkinase PF00069.25 KLO20381.1 - 1e-60 205.4 0.0 1.3e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO20381.1 - 4e-30 104.9 0.0 5.7e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO20381.1 - 9e-09 35.0 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KLO20381.1 - 0.01 15.7 0.6 0.03 14.2 0.2 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KLO20381.1 - 0.042 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KLO20381.1 - 0.091 12.4 0.1 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF373 PF04123.13 KLO20382.1 - 0.32 10.4 2.4 0.41 10.0 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) UPF0182 PF03699.13 KLO20383.1 - 4.1 5.4 11.8 0.25 9.4 1.3 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0182) COG5 PF10392.9 KLO20384.1 - 4.2e-24 85.2 1.9 1.6e-23 83.4 1.9 2.0 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Cas9-BH PF16593.5 KLO20384.1 - 0.0073 16.0 0.8 0.023 14.4 0.8 1.9 1 0 0 1 1 1 1 Bridge helix of CRISPR-associated endonuclease Cas9 Snapin_Pallidin PF14712.6 KLO20384.1 - 0.11 12.9 1.7 0.2 12.1 0.3 2.2 2 0 0 2 2 2 0 Snapin/Pallidin COG2 PF06148.11 KLO20384.1 - 0.48 10.5 2.3 9.1 6.4 1.8 3.4 2 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 KLO20384.1 - 4.3 7.9 6.9 2.8 8.5 0.4 3.8 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF3759 PF12585.8 KLO20385.1 - 0.00016 21.6 0.3 0.0003 20.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) WD40 PF00400.32 KLO20386.1 - 1.9e-09 38.0 1.5 0.0074 17.1 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO20386.1 - 2.8e-07 30.7 0.0 0.083 13.2 0.0 4.3 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Syncollin PF15138.6 KLO20386.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Syncollin DUF3792 PF12670.7 KLO20387.1 - 8.8 6.5 16.3 1.4 9.1 7.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) MFS_1 PF07690.16 KLO20388.1 - 1.1e-30 106.8 32.6 1.1e-30 106.8 32.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5368 PF17336.2 KLO20388.1 - 0.16 12.1 2.4 0.32 11.2 0.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5368) DUF2070 PF09843.9 KLO20388.1 - 1.7 6.8 6.9 3.4 5.9 6.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FAD_binding_3 PF01494.19 KLO20389.1 - 4.7e-20 72.1 0.0 1.1e-19 70.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KLO20389.1 - 0.0018 17.9 0.4 1.7 8.2 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KLO20389.1 - 0.0044 17.2 0.6 0.011 16.0 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KLO20389.1 - 0.08 12.2 1.1 0.2 10.8 0.7 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KLO20389.1 - 0.099 13.2 0.3 0.36 11.4 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KLO20389.1 - 0.16 12.0 0.0 2.1 8.3 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding DOT1 PF08123.13 KLO20391.1 - 3.4e-59 199.8 0.0 4.7e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 KLO20391.1 - 0.013 16.1 0.0 0.027 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KLO20391.1 - 0.023 15.4 0.0 0.053 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_2 PF03446.15 KLO20392.1 - 1.3e-22 80.7 0.0 2.5e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KLO20392.1 - 1.7e-11 44.4 0.0 3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 KLO20392.1 - 1.4e-06 28.4 0.0 3.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KLO20392.1 - 0.0003 21.3 0.0 0.00078 20.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Actin PF00022.19 KLO20393.1 - 4e-40 137.7 0.0 1.7e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 Actin RED_C PF07807.11 KLO20393.1 - 0.017 15.6 0.0 0.017 15.6 0.0 3.7 3 1 1 4 4 4 0 RED-like protein C-terminal region CRT10 PF08728.10 KLO20393.1 - 1.5 6.9 6.2 0.22 9.7 1.3 1.7 1 1 1 2 2 2 0 CRT10 Noggin PF05806.12 KLO20393.1 - 1.9 8.3 5.5 5.2 6.9 5.5 1.7 1 0 0 1 1 1 0 Noggin Ras PF00071.22 KLO20394.1 - 6.2e-63 211.2 0.0 7.3e-63 211.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO20394.1 - 1.3e-34 119.0 0.1 2.1e-34 118.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO20394.1 - 3.2e-13 49.5 0.0 3.9e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KLO20394.1 - 2.5e-05 23.9 0.2 5.6e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KLO20394.1 - 2.9e-05 23.6 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KLO20394.1 - 8.5e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO20394.1 - 0.0015 18.4 0.1 0.26 11.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KLO20394.1 - 0.018 15.4 0.0 0.033 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KLO20394.1 - 0.021 14.4 0.0 0.32 10.5 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 KLO20394.1 - 0.039 13.7 0.1 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.23 KLO20394.1 - 0.04 13.0 0.0 0.28 10.3 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain SRPRB PF09439.10 KLO20394.1 - 0.046 13.1 0.0 0.06 12.8 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MreB_Mbl PF06723.13 KLO20394.1 - 0.057 12.2 0.1 0.08 11.7 0.1 1.1 1 0 0 1 1 1 0 MreB/Mbl protein Septin PF00735.18 KLO20394.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Septin NACHT PF05729.12 KLO20394.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KLO20394.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter UvrD_C PF13361.6 KLO20395.1 - 7.7e-10 38.7 0.0 5.4e-08 32.6 0.0 3.1 3 1 1 4 4 4 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KLO20395.1 - 2.3e-07 30.7 0.3 2.3e-07 30.7 0.3 3.7 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KLO20395.1 - 9.5e-07 28.6 0.0 0.0068 16.2 0.2 2.9 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KLO20395.1 - 1.7e-06 28.4 0.0 3.8e-05 24.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KLO20395.1 - 0.00012 22.3 0.2 0.7 10.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain SNAP PF14938.6 KLO20395.1 - 0.00047 19.7 3.8 0.0012 18.3 3.8 1.6 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP AAA_30 PF13604.6 KLO20395.1 - 0.0015 18.3 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KLO20395.1 - 0.011 16.2 0.5 0.043 14.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_12 PF13087.6 KLO20395.1 - 0.013 15.1 0.0 0.049 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 KLO20395.1 - 0.015 15.4 12.7 0.41 10.9 0.0 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KLO20395.1 - 0.036 13.9 7.1 5.4 7.0 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ResIII PF04851.15 KLO20395.1 - 0.053 13.5 1.6 0.16 12.0 0.0 2.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit TPR_16 PF13432.6 KLO20395.1 - 8.7 7.1 10.3 1.2e+02 3.4 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.27 KLO20396.1 - 2e-26 93.1 0.0 1e-25 90.9 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KLO20396.1 - 1e-10 41.9 1.4 2.3e-07 30.9 0.7 2.8 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KLO20396.1 - 8.2e-07 28.7 0.0 0.02 14.3 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KLO20396.1 - 1.7e-05 24.7 0.0 0.0068 16.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KLO20396.1 - 0.0045 17.3 0.0 0.089 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KLO20396.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KLO20396.1 - 0.0062 16.3 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KLO20396.1 - 0.0097 16.3 0.2 0.034 14.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KLO20396.1 - 0.017 15.6 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KLO20396.1 - 0.018 15.0 0.0 0.21 11.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 KLO20396.1 - 0.086 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KLO20396.1 - 0.089 13.0 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 KLO20396.1 - 0.12 11.5 0.0 0.76 8.9 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.6 KLO20396.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Nic96 PF04097.14 KLO20397.1 - 1.4e-147 492.8 0.0 2e-147 492.3 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 TPR_4 PF07721.14 KLO20397.1 - 0.096 13.4 8.3 23 6.0 2.7 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KLO20397.1 - 0.85 9.9 3.8 50 4.4 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Cullin PF00888.22 KLO20398.1 - 0.012 14.3 0.0 0.017 13.7 0.0 1.1 1 0 0 1 1 1 0 Cullin family Mpv17_PMP22 PF04117.12 KLO20399.1 - 1.7e-22 79.4 0.1 2.5e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Coilin_N PF15862.5 KLO20400.1 - 1.4e-05 24.9 5.6 1.4e-05 24.9 5.6 3.3 4 1 0 4 4 4 1 Coilin N-terminus AF-4 PF05110.13 KLO20400.1 - 0.00018 19.8 39.5 0.00023 19.5 39.5 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein REV PF00424.18 KLO20400.1 - 0.035 14.1 1.3 0.09 12.8 0.4 2.3 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DUF4692 PF15763.5 KLO20400.1 - 4.3 7.8 14.5 16 5.9 14.5 2.0 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DnaJ PF00226.31 KLO20402.1 - 5.4e-14 52.1 0.2 1.5e-13 50.7 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KLO20402.1 - 2.1e-13 50.0 0.0 1.3e-12 47.4 0.0 2.3 1 1 0 1 1 1 1 Sec63 Brl domain HAUS4 PF14735.6 KLO20402.1 - 0.025 14.3 0.1 7.8 6.1 0.0 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 SLATT_3 PF18184.1 KLO20402.1 - 0.093 12.9 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 PUF PF00806.19 KLO20403.1 - 6.5e-56 183.0 14.1 1.5e-07 30.7 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Atg14 PF10186.9 KLO20404.1 - 2.3e-14 53.2 0.0 5.8e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KLO20404.1 - 3.1e-06 26.3 0.8 0.0011 17.9 0.4 3.4 3 1 0 3 3 3 2 Vacuolar protein sorting 38 ExoD PF06055.12 KLO20404.1 - 0.0091 15.4 2.1 0.015 14.7 2.1 1.3 1 0 0 1 1 1 1 Exopolysaccharide synthesis, ExoD Spectrin PF00435.21 KLO20404.1 - 0.047 14.2 3.0 0.091 13.3 3.0 1.5 1 0 0 1 1 1 0 Spectrin repeat APG6 PF04111.12 KLO20404.1 - 0.2 11.6 0.0 0.34 10.9 0.0 1.2 1 0 0 1 1 1 0 Apg6 BARA domain UPF0242 PF06785.11 KLO20404.1 - 0.2 11.8 2.4 0.34 11.0 2.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Med2 PF11214.8 KLO20405.1 - 0.0036 17.4 0.7 0.0062 16.7 0.7 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 Sipho_Gp37 PF14594.6 KLO20405.1 - 0.054 12.5 2.3 0.089 11.8 2.1 1.4 1 1 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein SprT-like PF10263.9 KLO20406.1 - 5.1e-31 106.9 0.7 1e-30 105.9 0.7 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KLO20406.1 - 5.8e-06 26.1 1.6 1.6e-05 24.7 1.6 1.8 1 0 0 1 1 1 1 SprT-like zinc ribbon domain p450 PF00067.22 KLO20407.1 - 1.8e-58 198.5 0.0 5e-58 197.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Acatn PF13000.7 KLO20408.1 - 5.1e-145 484.1 23.0 1.6e-71 241.5 16.5 3.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Rhodanese PF00581.20 KLO20410.1 - 9e-15 55.1 0.0 6.2e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain V-ATPase_C PF03223.15 KLO20411.1 - 1.5e-124 416.2 1.5 1.7e-124 416.0 1.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C SHE3 PF17078.5 KLO20411.1 - 0.03 14.0 0.3 0.069 12.9 0.3 1.6 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 KH_1 PF00013.29 KLO20412.1 - 1.8e-42 143.0 1.5 1.5e-08 34.3 0.0 7.4 7 0 0 7 7 7 7 KH domain IBR PF01485.21 KLO20413.1 - 3e-18 65.8 39.4 7.6e-13 48.5 5.2 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 KLO20413.1 - 7.3e-12 45.6 0.0 1.5e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_UBOX PF13445.6 KLO20413.1 - 4.7e-06 26.5 9.7 4.7e-06 26.5 9.7 3.8 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KLO20413.1 - 7e-05 23.1 12.1 7e-05 23.1 12.1 4.8 4 1 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 KLO20413.1 - 7.5e-05 22.6 11.3 7.5e-05 22.6 11.3 4.5 3 3 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KLO20413.1 - 0.00041 20.1 8.7 0.00041 20.1 8.7 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KLO20413.1 - 0.001 18.9 8.6 0.001 18.9 8.6 4.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Elf1 PF05129.13 KLO20413.1 - 0.0095 16.0 1.2 0.0095 16.0 1.2 3.3 3 1 0 3 3 3 1 Transcription elongation factor Elf1 like zf-RING_11 PF17123.5 KLO20413.1 - 0.02 14.6 8.8 0.02 14.6 8.8 2.1 2 0 0 2 2 2 0 RING-like zinc finger FYVE PF01363.21 KLO20413.1 - 6.9 6.9 31.9 1.6 8.9 6.6 3.5 3 0 0 3 3 3 0 FYVE zinc finger Urb2 PF10441.9 KLO20414.1 - 1.1e-48 166.0 0.2 4e-48 164.1 0.0 2.2 2 0 0 2 2 2 1 Urb2/Npa2 family FANCI_S2 PF14676.6 KLO20414.1 - 0.052 13.8 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 FANCI solenoid 2 SRP54_N PF02881.19 KLO20414.1 - 0.078 13.2 0.0 9.4 6.5 0.0 3.0 1 1 1 2 2 2 0 SRP54-type protein, helical bundle domain TRAPP PF04051.16 KLO20415.1 - 9.9e-39 132.4 0.0 1.2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DHO_dh PF01180.21 KLO20416.1 - 3.9e-14 52.6 0.0 6.8e-14 51.8 0.0 1.3 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase HMG_box PF00505.19 KLO20417.1 - 8e-13 48.6 0.1 1.5e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KLO20417.1 - 0.00036 21.1 0.0 0.00066 20.2 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain PHC2_SAM_assoc PF16616.5 KLO20417.1 - 0.3 11.9 11.5 0.4 11.5 1.0 2.3 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 PARP PF00644.20 KLO20418.1 - 1.9e-57 194.0 0.8 3e-57 193.4 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KLO20418.1 - 7e-41 139.5 0.0 1.3e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KLO20418.1 - 5.4e-22 77.7 2.0 1.4e-21 76.3 0.7 2.3 2 0 0 2 2 2 1 WGR domain DTHCT PF08070.11 KLO20418.1 - 0.021 15.5 14.2 0.021 15.5 14.2 2.0 2 0 0 2 2 2 0 DTHCT (NUC029) region Spt5_N PF11942.8 KLO20418.1 - 8 7.5 13.5 0.3 12.1 3.3 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal MFAP1 PF06991.11 KLO20419.1 - 3.2e-69 233.1 29.2 3.2e-69 233.1 29.2 3.2 3 1 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing zf-CCHC PF00098.23 KLO20419.1 - 0.23 11.6 1.3 0.51 10.5 1.3 1.6 1 1 0 1 1 1 0 Zinc knuckle UMP1 PF05348.11 KLO20420.1 - 1.8e-33 115.2 0.8 2.3e-33 114.9 0.8 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 NAD_binding_8 PF13450.6 KLO20421.1 - 2.8e-14 53.1 0.0 7e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KLO20421.1 - 4.2e-06 26.3 0.0 4.3e-05 23.0 0.0 2.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KLO20421.1 - 0.00018 21.5 0.0 0.00097 19.2 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KLO20421.1 - 0.00051 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KLO20421.1 - 0.0045 16.1 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KLO20421.1 - 0.011 15.0 0.0 0.044 13.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO20421.1 - 0.021 14.1 0.1 0.048 12.9 0.0 1.6 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 KLO20421.1 - 0.093 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain CRM1_repeat PF18777.1 KLO20422.1 - 0.24 11.0 0.2 21 4.7 0.3 2.4 2 0 0 2 2 2 0 Chromosome region maintenance or exportin repeat DHFR_2 PF06442.11 KLO20423.1 - 0.12 12.3 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 R67 dihydrofolate reductase zf-MYND PF01753.18 KLO20425.1 - 0.043 13.9 4.3 0.092 12.9 4.3 1.5 1 0 0 1 1 1 0 MYND finger SF3a60_bindingd PF12108.8 KLO20425.1 - 0.051 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Myb_DNA-binding PF00249.31 KLO20426.1 - 2.2e-39 133.4 6.8 1.1e-13 51.1 0.1 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KLO20426.1 - 9.6e-35 118.6 0.4 2.5e-13 50.1 0.2 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain zf-C2H2_aberr PF17017.5 KLO20426.1 - 9e-06 25.9 2.8 0.18 11.9 0.5 3.1 2 1 1 3 3 3 2 Aberrant zinc-finger SANT_DAMP1_like PF16282.5 KLO20426.1 - 0.00022 21.3 0.3 0.36 11.1 0.1 2.5 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 KLO20426.1 - 0.0043 17.1 0.0 9.6 6.3 0.0 3.4 2 1 0 3 3 3 2 SLIDE zf-C2H2_4 PF13894.6 KLO20426.1 - 0.07 14.0 8.3 37 5.5 2.0 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.15 KLO20426.1 - 0.59 10.2 6.5 0.45 10.6 1.6 2.8 3 0 0 3 3 3 0 BED zinc finger zf-C2H2 PF00096.26 KLO20426.1 - 1.1 9.9 11.6 0.24 11.9 4.5 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Baculo_PEP_C PF04513.12 KLO20427.1 - 2.6 8.1 4.7 3 7.9 3.7 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KLO20427.1 - 4.6 6.0 15.4 10 4.9 15.4 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc7 PF08317.11 KLO20428.1 - 1e-86 290.7 12.3 1.5e-86 290.1 12.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KLO20428.1 - 2.5e-05 24.3 0.0 5.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Spc7_C2 DUF4315 PF14193.6 KLO20428.1 - 0.023 14.7 5.5 0.52 10.4 3.7 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4315) Atg14 PF10186.9 KLO20428.1 - 0.11 11.5 3.0 0.22 10.6 3.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 KLO20428.1 - 0.2 11.8 1.6 0.63 10.2 1.6 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KLO20428.1 - 0.4 10.7 10.3 0.81 9.8 10.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 KLO20428.1 - 3.7 7.6 14.1 10 6.2 14.1 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BTB PF00651.31 KLO20430.1 - 0.014 15.7 0.0 0.053 13.8 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain DNA_pol_B_thumb PF14791.6 KLO20430.1 - 0.088 13.0 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta thumb Kinesin PF00225.23 KLO20433.1 - 1.4e-85 287.2 0.0 5.9e-85 285.1 0.0 2.0 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KLO20433.1 - 2.2e-17 63.4 0.0 7.6e-14 51.9 0.0 3.2 3 0 0 3 3 3 2 Microtubule binding TetR_C_11 PF16859.5 KLO20433.1 - 0.06 13.7 0.3 0.17 12.2 0.3 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Beta_elim_lyase PF01212.21 KLO20434.1 - 2.6e-69 233.7 0.0 3.5e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase zf-met2 PF12907.7 KLO20435.1 - 2.3e-11 43.6 1.1 3.1e-11 43.2 1.1 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KLO20435.1 - 5.8e-06 27.1 8.6 1.1e-05 26.1 8.6 1.5 1 0 0 1 1 1 1 4F5 protein family zf-Tim10_DDP PF02953.15 KLO20436.1 - 1.3e-21 76.0 0.4 1.6e-21 75.7 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger WD40 PF00400.32 KLO20437.1 - 5.3e-10 39.7 23.3 0.0051 17.6 0.2 9.3 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO20437.1 - 1.3e-08 35.0 0.0 0.021 15.1 0.0 6.0 7 0 0 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO20437.1 - 0.0086 15.1 0.3 5.3 5.9 0.0 3.9 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BAT PF15915.5 KLO20437.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 GAF and HTH_10 associated domain Prothymosin PF03247.14 KLO20437.1 - 0.95 10.0 10.7 0.026 15.0 3.7 1.9 2 0 0 2 2 2 0 Prothymosin/parathymosin family DNA_pol_phi PF04931.13 KLO20437.1 - 1.6 6.8 4.4 2.5 6.1 4.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Dopey_N PF04118.14 KLO20438.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Dopey, N-terminal Ion_trans_2 PF07885.16 KLO20439.1 - 5.6e-25 87.1 31.7 4.7e-13 48.9 8.9 2.9 3 0 0 3 3 3 2 Ion channel Lig_chan PF00060.26 KLO20439.1 - 0.043 13.7 4.8 0.73 9.7 0.1 2.7 1 1 0 2 2 2 0 Ligand-gated ion channel Ribosomal_S14 PF00253.21 KLO20440.1 - 4.4e-12 45.6 2.6 4.7e-12 45.5 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e OPT PF03169.15 KLO20441.1 - 4.1e-183 610.4 60.0 4.7e-183 610.2 60.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TauD PF02668.16 KLO20442.1 - 2.6e-52 178.3 0.3 3.4e-52 177.9 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Prp19 PF08606.11 KLO20443.1 - 1.8e-32 111.1 2.0 4.1e-32 110.0 2.0 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 KLO20443.1 - 4e-08 33.8 0.8 0.027 15.4 0.0 5.4 4 1 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO20443.1 - 5.1e-07 29.9 0.0 0.0014 18.9 0.0 4.3 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 KLO20443.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Frtz PF11768.8 KLO20443.1 - 0.0049 15.3 0.0 0.0077 14.6 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF4763 PF15960.5 KLO20443.1 - 0.042 13.2 0.3 0.075 12.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) zf-NOSIP PF15906.5 KLO20443.1 - 0.18 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein SGTA_dimer PF16546.5 KLO20444.1 - 3.5e-25 87.6 1.2 4e-25 87.4 0.1 1.7 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KLO20444.1 - 7.5e-14 50.9 1.1 2.9e-06 26.8 0.4 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KLO20444.1 - 1e-13 50.7 2.6 5.2e-10 38.8 1.6 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 KLO20444.1 - 7.1e-09 35.1 0.2 0.00041 20.2 0.1 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KLO20444.1 - 1.2e-08 34.7 0.1 0.00037 20.7 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KLO20444.1 - 1.9e-06 27.6 0.0 0.066 13.5 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KLO20444.1 - 9.4e-05 23.0 0.1 0.00017 22.1 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KLO20444.1 - 0.0018 18.5 0.2 0.0061 16.8 0.2 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KLO20444.1 - 0.036 13.9 0.8 4.7 7.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat FAM101 PF15068.6 KLO20444.1 - 0.061 13.3 0.1 0.082 12.8 0.1 1.2 1 0 0 1 1 1 0 FAM101 family TPR_14 PF13428.6 KLO20444.1 - 0.087 13.7 0.0 0.44 11.5 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3285 PF11688.8 KLO20445.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3285) C2 PF00168.30 KLO20446.1 - 2.3e-93 307.3 0.5 2.4e-18 66.3 0.0 5.4 5 0 0 5 5 5 5 C2 domain GST_N PF02798.20 KLO20447.1 - 8.4e-07 29.2 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KLO20447.1 - 0.00052 20.4 0.0 0.00089 19.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KLO20447.1 - 0.0077 16.5 0.0 0.034 14.5 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Mito_carr PF00153.27 KLO20448.1 - 4.9e-16 58.4 0.1 0.012 15.5 0.0 4.9 4 1 0 4 4 4 4 Mitochondrial carrier protein FUSC-like PF12805.7 KLO20449.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Ribosomal_L2_C PF03947.18 KLO20449.1 - 0.21 11.8 0.0 0.32 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain RNase_H PF00075.24 KLO20451.1 - 0.067 13.4 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 RNase H Aminotran_5 PF00266.19 KLO20452.1 - 3.6e-41 141.4 0.0 5.7e-41 140.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KLO20452.1 - 0.14 10.7 0.2 0.36 9.3 0.0 1.7 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme CCB1 PF12046.8 KLO20454.1 - 0.0092 15.3 1.7 0.35 10.2 0.3 2.9 2 1 0 2 2 2 1 Cofactor assembly of complex C subunit B DUF2742 PF10888.8 KLO20454.1 - 0.066 13.5 2.0 4.1 7.7 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2742) BLF1 PF17752.1 KLO20454.1 - 0.31 10.3 2.8 12 5.1 0.1 3.2 1 1 2 3 3 3 0 Burkholderia lethal factor 1 QCR10 PF09796.9 KLO20454.1 - 0.55 10.3 7.5 23 5.1 0.0 5.2 2 2 5 7 7 7 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) WD40 PF00400.32 KLO20456.1 - 9.8e-33 111.7 13.3 5.4e-07 30.2 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO20456.1 - 8e-11 42.1 0.0 0.035 14.4 0.0 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KLO20456.1 - 0.0046 15.5 0.0 1.5 7.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Raftlin PF15250.6 KLO20456.1 - 0.011 14.5 0.4 0.017 13.9 0.4 1.1 1 0 0 1 1 1 0 Raftlin PQQ_2 PF13360.6 KLO20456.1 - 0.05 13.2 0.0 3.1 7.3 0.0 2.6 2 1 1 3 3 3 0 PQQ-like domain PD40 PF07676.12 KLO20456.1 - 0.1 12.6 0.5 6 6.9 0.2 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat zf-HC5HC2H_2 PF13832.6 KLO20457.1 - 9.3e-33 112.7 14.0 1.1e-31 109.3 8.7 3.1 3 0 0 3 3 3 1 PHD-zinc-finger like domain EPL1 PF10513.9 KLO20457.1 - 1.1e-24 87.7 0.3 4.2e-24 85.7 0.3 2.1 1 0 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KLO20457.1 - 4.8e-24 84.4 6.1 4.8e-24 84.4 6.1 2.8 2 1 0 2 2 2 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KLO20457.1 - 3.4e-19 68.7 0.3 7.4e-19 67.6 0.3 1.6 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 KLO20457.1 - 9.9e-15 53.8 3.0 9.9e-15 53.8 3.0 3.1 3 0 0 3 3 3 2 PHD-finger PWWP PF00855.17 KLO20457.1 - 1.7e-13 50.8 1.9 3.9e-13 49.6 0.4 2.3 2 0 0 2 2 2 1 PWWP domain PHD PF00628.29 KLO20457.1 - 1.4e-10 40.9 5.5 1.4e-10 40.9 5.5 3.1 3 1 0 3 3 3 1 PHD-finger zf-PHD-like PF15446.6 KLO20457.1 - 0.0041 16.8 0.7 0.0041 16.8 0.7 2.3 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KLO20457.1 - 0.02 14.8 0.5 0.02 14.8 0.5 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KLO20457.1 - 5.8 7.3 20.8 1.2 9.5 2.5 3.2 3 0 0 3 3 3 0 C1 domain NUDIX PF00293.28 KLO20458.1 - 6.8e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain MCM PF00493.23 KLO20460.1 - 3.1e-104 346.9 0.0 6.1e-104 346.0 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KLO20460.1 - 7.3e-35 119.6 0.0 1.6e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KLO20460.1 - 5.6e-29 100.4 1.3 1.3e-28 99.3 1.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KLO20460.1 - 3.3e-14 53.3 0.1 2.5e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KLO20460.1 - 8.9e-07 28.5 0.0 0.00025 20.5 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KLO20460.1 - 0.0001 22.3 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KLO20460.1 - 0.001 18.9 0.2 0.0047 16.8 0.1 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 KLO20460.1 - 0.031 14.9 1.5 0.22 12.2 0.3 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 KLO20460.1 - 0.037 14.4 0.3 0.098 13.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MitMem_reg PF13012.6 KLO20461.1 - 5.9e-25 87.9 0.0 9.3e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KLO20461.1 - 1.1e-15 57.6 0.0 2.1e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SelK_SelG PF10961.8 KLO20461.1 - 0.34 11.6 3.2 0.16 12.6 1.0 1.6 2 0 0 2 2 2 0 Selenoprotein SelK_SelG DUF4149 PF13664.6 KLO20462.1 - 2.3e-24 85.6 3.4 2.3e-24 85.6 3.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) LapA_dom PF06305.11 KLO20462.1 - 0.33 10.8 0.0 0.33 10.8 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain LRR_9 PF14580.6 KLO20463.1 - 1.7e-61 206.7 0.1 2.6e-61 206.2 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KLO20463.1 - 2.9e-08 33.9 15.4 2.8e-05 24.4 5.3 3.4 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KLO20463.1 - 8.5e-08 31.8 2.7 3.2e-07 30.0 2.8 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 KLO20463.1 - 0.046 13.8 4.8 33 4.9 0.3 5.0 6 0 0 6 6 6 0 Leucine Rich repeat OAD_gamma PF04277.13 KLO20463.1 - 0.31 11.7 2.1 0.57 10.8 2.1 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain LRR_1 PF00560.33 KLO20463.1 - 0.66 10.7 3.0 1.3e+02 3.8 0.1 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat Syja_N PF02383.18 KLO20464.1 - 9.2e-79 265.0 0.0 1.1e-78 264.7 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain POTRA_2 PF08479.11 KLO20464.1 - 0.068 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type Pkinase PF00069.25 KLO20465.1 - 8.5e-41 140.1 0.0 2.2e-20 73.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KLO20465.1 - 9.1e-10 38.3 0.0 3.4e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO20465.1 - 0.0011 17.9 0.2 0.0038 16.1 0.2 1.9 1 1 0 1 1 1 1 Fungal protein kinase RNase_H PF00075.24 KLO20466.1 - 0.0037 17.4 0.0 0.0065 16.7 0.0 1.4 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KLO20466.1 - 0.0049 16.7 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like Polysacc_deac_1 PF01522.21 KLO20467.1 - 5.9e-28 97.2 0.0 1.6e-27 95.9 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase NAP PF00956.18 KLO20470.1 - 3.5e-25 88.7 10.1 2.1e-24 86.1 10.1 2.2 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) YL1 PF05764.13 KLO20470.1 - 3.3 7.7 10.2 0.15 12.1 3.1 2.0 2 0 0 2 2 2 0 YL1 nuclear protein GDPD PF03009.17 KLO20471.1 - 9.3e-36 123.9 0.0 1.5e-35 123.2 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KLO20471.1 - 5.1e-07 29.9 0.8 1.6e-05 25.2 0.4 2.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Rieske PF00355.26 KLO20472.1 - 2.8e-11 43.2 0.0 4.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KLO20472.1 - 4.8e-10 39.8 1.3 1.2e-09 38.5 1.3 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Pkinase PF00069.25 KLO20473.1 - 1.7e-49 168.6 0.0 3.5e-49 167.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO20473.1 - 2.8e-37 128.4 0.0 4.5e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KLO20473.1 - 1.3e-07 30.8 0.0 2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KLO20473.1 - 0.03 13.6 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KLO20473.1 - 0.096 12.6 0.1 0.3 11.0 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family CHCH PF06747.13 KLO20475.1 - 0.00012 22.1 1.5 0.00055 20.0 1.3 2.0 1 1 1 2 2 2 2 CHCH domain Pet191_N PF10203.9 KLO20475.1 - 0.0078 16.5 2.7 0.032 14.5 2.6 1.8 1 1 1 2 2 2 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 KLO20475.1 - 0.0079 16.2 2.5 0.011 15.7 2.5 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 KLO20475.1 - 0.044 14.2 2.0 1.2 9.5 0.3 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KLO20475.1 - 0.2 11.7 2.5 1.6 8.8 0.4 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like bZIP_2 PF07716.15 KLO20476.1 - 1.5e-10 40.9 8.1 3.8e-09 36.5 8.2 2.2 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KLO20476.1 - 7.3e-05 22.8 6.6 0.00016 21.7 6.6 1.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KLO20476.1 - 0.0023 18.4 1.4 0.0039 17.7 1.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor V_ATPase_I PF01496.19 KLO20476.1 - 0.36 8.7 0.4 0.43 8.4 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPL4 PF05021.15 KLO20477.1 - 9.7e-106 353.6 0.0 1.5e-105 353.0 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KLO20477.1 - 3.6e-63 212.0 0.1 7.4e-63 211.0 0.1 1.6 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KLO20477.1 - 0.00022 21.6 0.0 0.00055 20.4 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 DZR PF12773.7 KLO20477.1 - 6.7 6.8 11.2 0.11 12.5 2.1 2.6 3 0 0 3 3 3 0 Double zinc ribbon ATP-synt_F PF01990.17 KLO20478.1 - 9.6e-34 115.6 0.2 1.1e-33 115.3 0.2 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PIN_8 PF18476.1 KLO20478.1 - 0.025 14.4 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 PIN like domain DXP_synthase_N PF13292.6 KLO20478.1 - 0.067 12.4 0.0 0.068 12.4 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase PhaG_MnhG_YufB PF03334.14 KLO20479.1 - 0.0056 16.9 0.3 0.018 15.2 0.3 2.0 1 1 0 1 1 1 1 Na+/H+ antiporter subunit TBPIP PF07106.13 KLO20480.1 - 3.7e-18 65.2 1.4 3.2e-17 62.2 0.2 2.3 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain bZIP_1 PF00170.21 KLO20480.1 - 0.00093 19.3 2.0 0.00093 19.3 2.0 1.9 2 0 0 2 2 2 1 bZIP transcription factor Penicillinase_R PF03965.16 KLO20480.1 - 0.0093 16.3 0.9 0.018 15.4 0.4 1.8 2 0 0 2 2 2 1 Penicillinase repressor BRCT PF00533.26 KLO20480.1 - 0.013 15.9 0.1 0.86 10.0 0.1 2.9 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain TrmB PF01978.19 KLO20480.1 - 0.018 14.9 0.8 0.42 10.5 0.0 3.1 3 1 1 4 4 4 0 Sugar-specific transcriptional regulator TrmB TMCO5 PF14992.6 KLO20480.1 - 0.028 14.0 3.3 0.04 13.5 3.3 1.3 1 0 0 1 1 1 0 TMCO5 family Seadorna_VP6 PF07407.11 KLO20480.1 - 0.061 12.3 0.4 0.08 11.9 0.4 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein CENP-H PF05837.12 KLO20480.1 - 0.68 10.4 7.6 0.3 11.5 4.6 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.12 KLO20480.1 - 2.4 8.6 8.2 16 6.0 8.3 2.1 1 1 1 2 2 2 0 Cell division protein ZapB TIM21 PF08294.11 KLO20481.1 - 1.5e-20 73.6 0.0 5.4e-19 68.5 0.0 2.2 2 0 0 2 2 2 2 TIM21 Histone PF00125.24 KLO20482.1 - 1.1e-49 168.2 3.4 1.2e-49 168.0 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KLO20482.1 - 2.6e-05 24.5 0.1 4.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KLO20482.1 - 4.6e-05 23.5 0.1 8.5e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KLO20482.1 - 0.0012 19.0 1.4 0.0015 18.8 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KLO20482.1 - 0.0025 18.4 1.9 0.0033 18.0 1.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 KLO20482.1 - 0.087 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KLO20482.1 - 0.1 12.6 0.3 0.18 11.9 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Catalase PF00199.19 KLO20483.1 - 3.6e-169 562.9 0.0 4.4e-169 562.6 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KLO20483.1 - 1.2e-18 67.1 0.1 2.3e-18 66.1 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KLO20483.1 - 5.2e-12 45.6 0.0 9.8e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KLO20483.1 - 1e-07 31.9 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family zf-C2H2 PF00096.26 KLO20487.1 - 5.3e-09 36.0 21.5 2.6e-06 27.6 2.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO20487.1 - 7e-06 26.4 16.5 0.0011 19.6 1.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KLO20487.1 - 0.019 14.7 0.7 0.019 14.7 0.7 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type zf_ZIC PF18366.1 KLO20487.1 - 0.07 13.2 4.5 6.6 6.9 1.9 2.5 2 0 0 2 2 2 0 Zic proteins zinc finger domain Zn_ribbon_SprT PF17283.2 KLO20487.1 - 0.16 11.9 6.5 0.67 9.9 3.0 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Rpr2 PF04032.16 KLO20487.1 - 0.23 11.7 7.0 4.3 7.7 1.2 2.5 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_6 PF13912.6 KLO20487.1 - 0.24 11.4 7.3 0.22 11.6 2.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KLO20487.1 - 0.69 10.3 9.0 4.6 7.6 1.3 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KLO20487.1 - 0.96 10.1 5.4 4 8.2 1.1 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain HAD_2 PF13419.6 KLO20488.1 - 1.2e-17 64.5 0.0 4.5e-14 52.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KLO20488.1 - 4.2e-11 43.5 0.3 8.4e-09 36.0 0.3 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KLO20488.1 - 3.2e-05 24.4 0.0 4.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KLO20488.1 - 0.0001 22.3 0.0 0.027 14.6 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KLO20488.1 - 0.085 12.9 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 HAD-hyrolase-like EspF PF04806.12 KLO20488.1 - 0.14 12.6 6.0 1.4 9.3 0.2 2.9 4 0 0 4 4 4 0 EspF protein repeat SGT1 PF07093.11 KLO20489.1 - 3e-100 336.4 3.8 3.6e-65 220.5 0.4 3.4 4 0 0 4 4 4 3 SGT1 protein Clat_adaptor_s PF01217.20 KLO20490.1 - 2.2e-43 147.6 0.2 4.4e-43 146.6 0.2 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Med6 PF04934.14 KLO20491.1 - 1.4e-41 141.4 0.1 2.2e-41 140.8 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Nramp PF01566.18 KLO20492.1 - 1.2e-88 297.5 19.3 1.1e-50 172.6 4.3 2.1 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Chalcone_2 PF16035.5 KLO20493.1 - 1.6e-31 109.7 0.1 1.8e-19 70.4 0.0 2.2 1 1 1 2 2 2 2 Chalcone isomerase like GRA6 PF05084.13 KLO20493.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Granule antigen protein (GRA6) BLM10_mid PF16507.5 KLO20494.1 - 9.3e-184 611.9 0.0 1.3e-183 611.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KLO20494.1 - 1.1e-31 108.5 0.0 5.4e-31 106.4 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KLO20494.1 - 0.00093 19.3 0.5 0.049 13.9 0.1 4.0 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KLO20494.1 - 0.003 17.9 0.5 0.24 11.8 0.0 4.2 5 0 0 5 5 5 1 HEAT repeats TAF6_C PF07571.13 KLO20494.1 - 0.026 14.8 0.4 15 5.9 0.0 3.7 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain zf-CCCH PF00642.24 KLO20496.1 - 2.3e-17 62.5 13.5 2.4e-09 36.9 2.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KLO20496.1 - 2e-08 33.8 11.4 1.5e-05 24.6 1.0 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KLO20496.1 - 7.9e-08 32.1 12.8 2.4e-05 24.2 3.0 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 KLO20496.1 - 0.028 14.9 0.7 0.028 14.9 0.7 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KLO20496.1 - 2.5 8.8 8.3 1.6 9.5 1.9 2.5 1 1 1 2 2 2 0 Torus domain Choline_kinase PF01633.20 KLO20497.1 - 3e-52 177.3 0.0 4e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KLO20497.1 - 1.4e-10 41.5 0.1 2.4e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KLO20497.1 - 0.029 13.7 0.1 0.047 13.0 0.1 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase MFS_1 PF07690.16 KLO20499.1 - 9e-32 110.4 50.0 7.8e-31 107.3 50.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DnaJ_C PF01556.18 KLO20500.1 - 3.4e-37 127.8 0.0 5.9e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KLO20500.1 - 8.1e-24 83.5 3.4 1.2e-23 83.0 3.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KLO20500.1 - 2.1e-10 40.8 17.9 4e-10 39.9 17.9 1.5 1 0 0 1 1 1 1 DnaJ central domain SET PF00856.28 KLO20501.1 - 4.1e-05 24.0 0.0 0.0014 19.0 0.0 2.2 1 1 0 1 1 1 1 SET domain Pkinase PF00069.25 KLO20502.1 - 1.2e-63 214.9 0.2 1.5e-63 214.7 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO20502.1 - 2.6e-18 66.3 0.0 3.9e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KLO20502.1 - 4.4e-07 30.1 0.0 1.9e-05 24.7 0.3 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KLO20502.1 - 0.0087 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KLO20502.1 - 0.023 14.0 0.2 0.042 13.2 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KLO20502.1 - 0.055 13.0 0.1 0.055 13.0 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kinase-like PF14531.6 KLO20502.1 - 0.062 12.6 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Glyco_hydro_18 PF00704.28 KLO20503.1 - 2.6e-24 86.5 0.4 1.7e-23 83.8 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KLO20503.1 - 0.63 10.7 8.8 0.11 13.1 2.7 3.2 2 0 0 2 2 2 0 Carbohydrate binding domain DIE2_ALG10 PF04922.12 KLO20504.1 - 7.5e-128 427.2 5.2 9e-128 426.9 5.2 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family MTS PF05175.14 KLO20505.1 - 8e-06 25.5 0.0 0.00038 20.1 0.0 2.0 2 0 0 2 2 2 2 Methyltransferase small domain DNA_pol_A_exo1 PF01612.20 KLO20506.1 - 6.4e-09 35.8 0.0 0.00031 20.5 0.0 2.4 2 1 0 2 2 2 2 3'-5' exonuclease Pkinase_fungal PF17667.1 KLO20510.1 - 8.6e-88 294.8 5.8 1.9e-87 293.7 0.1 2.9 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 KLO20510.1 - 4.3e-08 32.8 0.0 1.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KLO20510.1 - 0.0013 18.1 0.0 0.0034 16.8 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KLO20510.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase AHJR-like PF18743.1 KLO20510.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 REase_AHJR-like RIO1 PF01163.22 KLO20510.1 - 0.13 11.9 0.0 0.71 9.4 0.0 2.2 2 0 0 2 2 2 0 RIO1 family BLM10_mid PF16507.5 KLO20513.1 - 5.1e-188 626.0 0.0 7.9e-188 625.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KLO20513.1 - 2e-30 104.5 0.1 9e-30 102.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KLO20513.1 - 4.8e-08 32.6 2.8 0.29 11.5 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KLO20513.1 - 6.6e-05 23.2 1.4 0.03 14.7 0.0 4.5 5 0 0 5 5 5 1 HEAT repeats Arm PF00514.23 KLO20513.1 - 0.001 19.0 0.5 0.27 11.3 0.1 3.9 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KLO20513.1 - 0.023 15.0 0.0 0.43 10.9 0.0 2.9 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain BLM10_N PF16547.5 KLO20513.1 - 0.032 14.5 0.0 0.093 13.0 0.0 1.8 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal CLASP_N PF12348.8 KLO20513.1 - 0.039 13.5 0.5 0.31 10.6 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal Cse1 PF08506.10 KLO20513.1 - 0.12 11.1 0.0 0.28 10.0 0.0 1.5 1 0 0 1 1 1 0 Cse1 MyTH4 PF00784.17 KLO20513.1 - 0.13 12.8 0.4 3.7 8.1 0.0 3.3 4 0 0 4 4 3 0 MyTH4 domain Vac14_Fab1_bd PF12755.7 KLO20513.1 - 0.16 12.6 0.8 9.1 7.0 0.0 3.8 5 0 0 5 5 3 0 Vacuolar 14 Fab1-binding region QVR PF17064.5 KLO20513.1 - 0.21 11.9 0.3 0.8 10.0 0.3 2.0 1 0 0 1 1 1 0 Sleepless protein RNase_T PF00929.24 KLO20515.1 - 1.7e-07 31.9 0.0 2.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Exonuclease BATS PF06968.13 KLO20516.1 - 1.7e-21 76.1 0.3 5.5e-21 74.5 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KLO20516.1 - 2.7e-17 63.7 0.1 4e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_S27e PF01667.17 KLO20517.1 - 5e-27 93.4 2.9 6.1e-27 93.1 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Mu-like_Com PF10122.9 KLO20517.1 - 0.028 13.9 0.6 4.5 6.8 0.1 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com zinc_ribbon_4 PF13717.6 KLO20517.1 - 0.067 13.1 2.6 1 9.3 2.6 2.3 1 1 0 1 1 1 0 zinc-ribbon domain XPA_C PF05181.12 KLO20518.1 - 1.3e-25 89.1 2.3 2.2e-25 88.3 2.3 1.4 1 0 0 1 1 1 1 XPA protein C-terminus zf-AD PF07776.15 KLO20518.1 - 0.009 16.2 0.8 4.5 7.6 1.0 2.6 2 0 0 2 2 2 2 Zinc-finger associated domain (zf-AD) RF3_C PF16658.5 KLO20518.1 - 0.016 15.0 0.5 0.046 13.5 0.1 1.9 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain FYVE PF01363.21 KLO20518.1 - 0.13 12.4 3.4 0.5 10.5 3.4 2.0 1 1 0 1 1 1 0 FYVE zinc finger XPA_N PF01286.18 KLO20518.1 - 0.21 11.7 6.0 0.68 10.0 2.2 2.6 2 0 0 2 2 2 0 XPA protein N-terminal zf-piccolo PF05715.13 KLO20518.1 - 3.7 7.8 7.4 14 6.0 0.1 3.0 3 0 0 3 3 3 0 Piccolo Zn-finger Hist_deacetyl PF00850.19 KLO20519.1 - 1.1e-83 281.3 0.0 1.6e-83 280.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DinB_2 PF12867.7 KLO20520.1 - 6.5e-06 26.7 0.0 8.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 DinB superfamily DUF3130 PF11328.8 KLO20520.1 - 0.15 12.3 0.0 2 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 BTG PF07742.12 KLO20521.1 - 1.2e-17 63.9 0.0 2.3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 BTG family DUF442 PF04273.13 KLO20521.1 - 0.081 13.0 0.3 0.21 11.7 0.3 1.7 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Translin PF01997.16 KLO20522.1 - 1.3e-62 211.5 0.0 1.5e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Translin family DcpS_C PF11969.8 KLO20523.1 - 0.00019 21.9 0.1 0.0014 19.1 0.0 2.0 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DUF3875 PF12991.7 KLO20523.1 - 0.0066 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3875) DUF5427 PF10310.9 KLO20524.1 - 1.4e-58 199.0 0.5 9.8e-54 183.0 0.0 2.4 1 1 1 2 2 2 2 Family of unknown function (DUF5427) DUF4719 PF15843.5 KLO20524.1 - 0.17 12.0 2.8 0.35 10.9 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) BCAS2 PF05700.11 KLO20525.1 - 2.3e-68 229.9 12.7 2.6e-68 229.8 12.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) VIR_N PF15912.5 KLO20525.1 - 0.005 16.5 2.2 0.0064 16.1 2.2 1.2 1 0 0 1 1 1 1 Virilizer, N-terminal Mesd PF10185.9 KLO20525.1 - 0.012 15.5 0.5 0.02 14.9 0.5 1.7 1 1 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor ZapB PF06005.12 KLO20525.1 - 0.084 13.3 1.0 0.084 13.3 1.0 4.2 1 1 2 3 3 3 0 Cell division protein ZapB SKA2 PF16740.5 KLO20525.1 - 1.6 8.6 8.7 0.35 10.7 3.6 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Syntaxin-6_N PF09177.11 KLO20525.1 - 2.8 8.5 8.1 9.1 6.9 6.2 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Complex1_30kDa PF00329.19 KLO20526.1 - 7.8e-44 149.2 0.0 1.1e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit ATP-grasp_2 PF08442.10 KLO20528.1 - 7.6e-72 241.1 0.4 1.2e-71 240.4 0.1 1.4 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KLO20528.1 - 1.7e-24 86.4 0.5 3e-24 85.6 0.5 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KLO20528.1 - 2.2e-10 40.4 0.8 8.2e-10 38.5 0.1 2.1 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KLO20528.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Chromo PF00385.24 KLO20529.1 - 1.2e-06 28.3 0.7 2.8e-06 27.1 0.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_C48 PF02902.19 KLO20530.1 - 1.1e-38 133.3 0.2 1.9e-38 132.5 0.2 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 KLO20530.1 - 0.047 12.4 0.4 0.073 11.8 0.4 1.3 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase Use1 PF09753.9 KLO20531.1 - 0.0076 16.0 0.0 0.0087 15.8 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.13 KLO20531.1 - 0.017 15.0 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Sec20 SNARE PF05739.19 KLO20531.1 - 0.33 11.0 2.8 0.51 10.4 2.8 1.3 1 0 0 1 1 1 0 SNARE domain RNB PF00773.19 KLO20532.1 - 1.1e-49 169.5 0.0 4.3e-49 167.6 0.0 1.9 2 0 0 2 2 2 1 RNB domain MtrD PF04207.12 KLO20533.1 - 0.0097 15.6 2.2 0.0097 15.6 2.2 1.8 2 0 0 2 2 2 1 Tetrahydromethanopterin S-methyltransferase, subunit D COX2_TM PF02790.15 KLO20533.1 - 0.29 11.3 10.2 0.18 12.0 0.7 3.1 2 2 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Spo7 PF03907.13 KLO20533.1 - 2.2 7.7 5.5 1 8.8 2.4 1.9 2 0 0 2 2 2 0 Spo7-like protein Oxidored_q2 PF00420.24 KLO20533.1 - 6.8 6.4 13.1 0.066 12.8 0.5 2.7 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PTH2 PF01981.16 KLO20534.1 - 6.8e-45 152.1 0.0 8.7e-45 151.8 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 MeaB PF03308.16 KLO20534.1 - 0.12 11.4 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2573 PF10835.8 KLO20534.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) MFS_1 PF07690.16 KLO20535.1 - 6.4e-16 58.2 41.4 2e-14 53.3 20.6 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Tim17 PF02466.19 KLO20536.1 - 2.9e-05 24.4 0.4 7e-05 23.2 0.2 1.7 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family BTB PF00651.31 KLO20537.1 - 0.05 13.8 0.0 0.18 12.0 0.0 1.9 1 1 1 2 2 2 0 BTB/POZ domain Sgf11 PF08209.11 KLO20538.1 - 9.8e-11 41.0 0.3 9.8e-11 41.0 0.3 1.7 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) BTB PF00651.31 KLO20539.1 - 3e-11 43.5 0.0 2.1e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain Yippee-Mis18 PF03226.14 KLO20542.1 - 6.1e-15 55.3 0.1 6.7e-15 55.2 0.1 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AlcCBM31 PF11606.8 KLO20542.1 - 0.013 15.7 0.1 0.73 10.0 0.0 2.1 1 1 1 2 2 2 0 Family 31 carbohydrate binding protein GFA PF04828.14 KLO20542.1 - 0.04 14.3 0.6 0.78 10.1 0.8 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.16 KLO20543.1 - 1.4e-22 80.1 28.6 5.6e-22 78.1 25.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L1 PF00687.21 KLO20544.1 - 1e-47 162.5 1.4 1.2e-47 162.3 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ras PF00071.22 KLO20548.1 - 3.8e-51 172.9 0.0 4.3e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO20548.1 - 6.1e-18 65.2 0.0 9.7e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO20548.1 - 3.6e-05 23.3 0.0 4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KLO20548.1 - 5.7e-05 22.7 0.0 0.00019 21.0 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KLO20548.1 - 0.0001 22.3 0.1 0.0055 16.6 0.0 2.1 1 1 1 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KLO20548.1 - 0.0047 16.5 0.1 0.12 11.9 0.1 2.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KLO20548.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 KLO20548.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KLO20548.1 - 0.15 12.5 0.9 0.63 10.4 0.9 2.0 1 1 0 1 1 1 0 AAA ATPase domain CBS PF00571.28 KLO20549.1 - 8.6e-35 119.0 8.2 1.1e-09 38.6 0.0 5.0 6 0 0 6 6 6 4 CBS domain PB1 PF00564.24 KLO20549.1 - 1.7e-07 31.1 0.0 2.4e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 PB1 domain GAF PF01590.26 KLO20549.1 - 2.7e-05 24.8 0.5 0.72 10.5 0.0 4.0 4 0 0 4 4 4 2 GAF domain PfkB PF00294.24 KLO20550.1 - 2.1e-08 33.9 0.0 3.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KLO20550.1 - 0.025 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase UPF0121 PF03661.13 KLO20551.1 - 1.3e-39 136.1 2.3 1.5e-39 135.8 2.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) PTH2 PF01981.16 KLO20552.1 - 3.1e-38 130.7 1.3 4.1e-38 130.3 0.8 1.4 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 DEAD PF00270.29 KLO20553.1 - 1.1e-45 155.6 0.0 1.9e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KLO20553.1 - 1.8e-24 86.2 0.0 1.7e-23 83.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KLO20553.1 - 5.2e-17 61.8 0.4 9.4e-17 61.0 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) PBP1_TM PF14812.6 KLO20553.1 - 0.02 15.3 9.0 0.066 13.6 9.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ResIII PF04851.15 KLO20553.1 - 0.024 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Trypan_PARP PF05887.11 KLO20553.1 - 0.12 12.4 0.5 0.2 11.6 0.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PhoH PF02562.16 KLO20553.1 - 0.42 10.0 2.4 0.68 9.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein MCM PF00493.23 KLO20554.1 - 1.9e-96 321.5 0.1 2.9e-96 320.9 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KLO20554.1 - 1.2e-35 122.1 0.0 2e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KLO20554.1 - 5.2e-22 78.1 0.9 9.4e-22 77.2 0.9 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KLO20554.1 - 8e-09 36.0 0.0 2.8e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KLO20554.1 - 1.2e-07 31.3 0.1 1.7e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KLO20554.1 - 0.0018 18.2 0.0 0.0075 16.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KLO20554.1 - 0.0076 16.0 0.1 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 KLO20554.1 - 0.02 14.9 0.2 0.13 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF3512 PF12024.8 KLO20555.1 - 0.028 13.9 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) L51_S25_CI-B8 PF05047.16 KLO20556.1 - 4e-08 33.1 0.1 7.5e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RPN2_C PF18004.1 KLO20560.1 - 1.3e-42 145.4 12.2 5.2e-41 140.2 11.4 2.8 2 1 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KLO20560.1 - 3.1e-38 128.3 17.9 9.3e-08 32.1 0.0 8.7 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KLO20560.1 - 2e-18 66.5 4.3 3.8e-14 52.8 0.1 4.5 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.22 KLO20560.1 - 0.00026 21.0 1.4 3.7 8.1 0.1 4.5 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.23 KLO20560.1 - 0.01 15.9 1.9 5.9 7.1 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KLO20560.1 - 0.16 12.5 9.3 5.3 7.6 0.0 5.2 4 1 2 6 6 6 0 HEAT-like repeat TPR_19 PF14559.6 KLO20560.1 - 0.24 12.0 2.2 4.7 7.8 0.3 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Cupredoxin_1 PF13473.6 KLO20561.1 - 2.8e-06 27.4 0.0 0.0055 16.8 0.0 2.8 3 0 0 3 3 3 2 Cupredoxin-like domain Cu_bind_like PF02298.17 KLO20561.1 - 2.7e-05 24.1 0.5 0.11 12.5 0.2 2.9 2 1 0 2 2 2 2 Plastocyanin-like domain AIP3 PF03915.13 KLO20563.1 - 0.011 14.8 0.3 0.02 14.0 0.3 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 Fib_alpha PF08702.10 KLO20563.1 - 1.7 8.8 4.1 0.65 10.2 0.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family LIM PF00412.22 KLO20564.1 - 3e-13 49.8 25.4 6.5e-06 26.3 1.7 5.5 5 1 0 5 5 5 4 LIM domain zf-RING_11 PF17123.5 KLO20564.1 - 0.47 10.3 7.1 0.72 9.6 1.3 3.2 3 0 0 3 3 3 0 RING-like zinc finger DnaJ PF00226.31 KLO20566.1 - 3.7e-19 68.6 2.6 5.8e-19 68.0 2.6 1.3 1 0 0 1 1 1 1 DnaJ domain AMP-binding PF00501.28 KLO20569.1 - 7.6e-82 275.2 1.0 8.9e-82 274.9 1.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KLO20569.1 - 7.5e-18 65.3 0.0 2e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GYF PF02213.16 KLO20570.1 - 3.9e-15 55.2 0.1 8.3e-15 54.2 0.1 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KLO20570.1 - 0.064 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 GYF domain 2 Cyclin_C_2 PF16899.5 KLO20571.1 - 1.8e-16 60.4 0.4 1.9e-13 50.7 0.0 3.1 3 0 0 3 3 3 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KLO20571.1 - 2.8e-09 36.8 0.0 4.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KLO20571.1 - 0.0047 16.9 0.0 0.032 14.3 0.0 2.1 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Sde2_N_Ubi PF13019.6 KLO20571.1 - 1.3 8.9 4.2 3.1 7.6 4.2 1.7 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain AAA_18 PF13238.6 KLO20573.1 - 8.5e-31 107.2 0.2 1.8e-30 106.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KLO20573.1 - 2.8e-09 37.5 0.1 1.3e-08 35.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 KLO20573.1 - 3.6e-07 30.4 0.3 0.00012 22.3 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase SKI PF01202.22 KLO20573.1 - 6.6e-07 29.6 0.0 8.9e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA PF00004.29 KLO20573.1 - 0.0002 21.8 0.1 0.00072 20.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KLO20573.1 - 0.00043 20.6 0.5 0.0013 19.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KLO20573.1 - 0.00052 20.2 0.5 0.033 14.4 0.1 2.3 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KLO20573.1 - 0.0013 19.0 0.0 0.0066 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KLO20573.1 - 0.0022 18.4 0.1 0.015 15.7 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain dNK PF01712.19 KLO20573.1 - 0.0036 17.2 1.4 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase NTPase_1 PF03266.15 KLO20573.1 - 0.0036 17.2 0.2 0.028 14.3 0.0 2.1 2 0 0 2 2 2 1 NTPase Thymidylate_kin PF02223.17 KLO20573.1 - 0.0045 16.7 0.8 1.9 8.1 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase KTI12 PF08433.10 KLO20573.1 - 0.0076 15.7 0.1 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ATPase PF06745.13 KLO20573.1 - 0.019 14.4 0.4 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 KLO20573.1 - 0.021 14.1 0.2 0.05 12.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DUF218 PF02698.17 KLO20573.1 - 0.027 14.5 0.2 0.19 11.8 0.1 2.0 2 0 0 2 2 2 0 DUF218 domain ABC_tran PF00005.27 KLO20573.1 - 0.028 14.9 0.2 0.054 14.0 0.2 1.7 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 KLO20573.1 - 0.036 14.5 0.0 0.079 13.4 0.0 1.6 2 0 0 2 2 1 0 RNA helicase AAA_29 PF13555.6 KLO20573.1 - 0.037 13.8 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KLO20573.1 - 0.049 12.7 0.3 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_11 PF13086.6 KLO20573.1 - 0.051 13.3 0.4 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KLO20573.1 - 0.059 13.1 0.7 0.18 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KLO20573.1 - 0.066 13.1 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Sigma54_activat PF00158.26 KLO20573.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 KLO20573.1 - 0.084 13.0 0.1 0.95 9.6 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family Hydin_ADK PF17213.3 KLO20573.1 - 0.09 13.0 0.5 0.16 12.2 0.1 1.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Sigma54_activ_2 PF14532.6 KLO20573.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.12 KLO20573.1 - 0.14 11.9 0.2 0.36 10.6 0.1 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KLO20573.1 - 2 8.7 3.9 0.63 10.4 0.7 1.8 2 1 0 2 2 2 0 AAA domain UPF0182 PF03699.13 KLO20574.1 - 6.9 4.7 7.1 9.3 4.2 7.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Ras PF00071.22 KLO20575.1 - 1.8e-55 187.0 0.0 2.2e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KLO20575.1 - 1e-33 116.1 0.0 1.6e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KLO20575.1 - 6.4e-15 55.0 0.0 5.5e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KLO20575.1 - 4.5e-06 26.4 0.0 5.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KLO20575.1 - 0.00015 21.2 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KLO20575.1 - 0.00018 22.0 0.4 0.00031 21.2 0.4 1.5 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KLO20575.1 - 0.00022 21.3 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO20575.1 - 0.084 12.8 0.2 9.4 6.1 0.0 2.9 2 1 0 2 2 2 0 RsgA GTPase PH_6 PF15406.6 KLO20575.1 - 0.15 12.4 0.3 0.32 11.3 0.1 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain Sin_N PF04801.13 KLO20576.1 - 2.2e-32 112.8 0.0 2.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region ARID PF01388.21 KLO20577.1 - 1.2e-14 54.7 0.0 1.2e-13 51.6 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 KLO20577.1 - 0.076 12.3 0.0 0.41 9.9 0.0 2.0 1 1 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa Rcd1 PF04078.13 KLO20577.1 - 0.21 10.9 0.0 0.43 9.8 0.0 1.4 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like FAD-oxidase_C PF02913.19 KLO20579.1 - 8.3e-52 176.3 0.0 1e-51 176.0 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KLO20579.1 - 3.8e-34 117.4 0.5 6e-34 116.8 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Myb_DNA-bind_2 PF08914.11 KLO20580.1 - 2.7e-10 40.3 0.5 7.1e-10 38.9 0.5 1.8 1 0 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 KLO20580.1 - 1.2e-09 38.4 0.0 3.3e-06 27.4 0.0 2.4 1 1 1 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KLO20580.1 - 0.24 12.0 3.4 1.1 9.9 2.2 2.3 1 1 1 2 2 2 0 Rap1, DNA-binding Pkinase PF00069.25 KLO20581.1 - 1.1e-66 224.9 0.0 1.3e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO20581.1 - 8.4e-26 90.8 0.0 1.2e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO20581.1 - 5.5e-06 25.9 0.1 0.0003 20.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KLO20581.1 - 0.0031 17.1 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family ABM PF03992.16 KLO20582.1 - 7.2e-12 45.3 0.0 9.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.6 KLO20582.1 - 0.066 13.6 0.0 0.073 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) ABM PF03992.16 KLO20583.1 - 5.5e-11 42.4 0.0 6.8e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.16 KLO20584.1 - 1.6e-09 37.7 0.0 2.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.16 KLO20585.1 - 1.2e-07 31.8 0.0 1.5e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.16 KLO20586.1 - 1.5e-07 31.4 0.0 2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.16 KLO20587.1 - 4.2e-09 36.4 0.0 5.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Cu_bind_like PF02298.17 KLO20588.1 - 0.00061 19.8 0.1 1.8 8.6 0.0 2.7 2 0 0 2 2 2 2 Plastocyanin-like domain DUF2207 PF09972.9 KLO20588.1 - 0.057 12.2 0.1 0.11 11.2 0.0 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) HCNGP PF07818.13 KLO20589.1 - 8.6e-32 109.7 0.1 1.2e-31 109.2 0.1 1.2 1 0 0 1 1 1 1 HCNGP-like protein Thioredoxin PF00085.20 KLO20590.1 - 8.7e-27 93.1 0.0 1.1e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KLO20590.1 - 5.7e-06 26.3 0.0 8.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KLO20590.1 - 2.6e-05 24.0 0.0 3.3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KLO20590.1 - 3.1e-05 24.4 0.1 0.00044 20.7 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KLO20590.1 - 3.1e-05 24.2 0.0 5.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KLO20590.1 - 0.017 14.9 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Redoxin OST3_OST6 PF04756.13 KLO20590.1 - 0.043 13.2 0.0 0.054 12.8 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Exo70 PF03081.15 KLO20590.1 - 0.21 10.6 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit TraF PF13728.6 KLO20590.1 - 0.21 11.3 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein RabGAP-TBC PF00566.18 KLO20592.1 - 1.7e-31 109.6 0.0 2.7e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KLO20592.1 - 0.0063 14.8 1.0 0.0063 14.8 1.0 1.7 2 0 0 2 2 2 1 SBE2, cell-wall formation GCP_C_terminal PF04130.13 KLO20593.1 - 1.2e-31 110.4 0.0 2.1e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KLO20593.1 - 2.8e-24 86.3 0.0 1.7e-22 80.5 0.0 2.2 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal Pyrophosphatase PF00719.19 KLO20594.1 - 9.4e-59 197.8 0.3 1.2e-58 197.4 0.3 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Pyocin_S PF06958.12 KLO20595.1 - 0.046 14.2 1.4 17 6.0 0.1 3.8 2 1 0 3 3 3 0 S-type Pyocin PAP_assoc PF03828.19 KLO20596.1 - 9.4e-07 29.0 0.0 2.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KLO20596.1 - 2e-06 28.0 0.0 4.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KLO20596.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase zf-C2H2 PF00096.26 KLO20597.1 - 3.1e-08 33.6 7.8 0.00097 19.5 3.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KLO20597.1 - 5.4e-06 26.8 5.5 0.0038 17.9 2.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KLO20597.1 - 0.024 14.9 2.0 0.073 13.4 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KLO20597.1 - 0.08 13.0 1.6 0.43 10.6 0.8 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KLO20597.1 - 0.1 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 KLO20597.1 - 0.24 11.9 8.7 0.5 10.9 0.8 3.4 3 0 0 3 3 3 0 Zinc-finger double domain PfkB PF00294.24 KLO20598.1 - 5.9e-68 229.4 0.8 6.8e-68 229.2 0.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KLO20598.1 - 0.0066 15.8 0.0 0.015 14.7 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Fer2_3 PF13085.6 KLO20598.1 - 0.2 11.7 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain RdRP PF05183.12 KLO20599.1 - 9.3e-105 351.5 0.0 1.2e-104 351.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RCC1 PF00415.18 KLO20600.1 - 2e-28 98.8 4.4 7.3e-09 36.1 0.2 6.8 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KLO20600.1 - 6.1e-09 35.4 17.0 0.022 14.6 0.0 6.6 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Swi5 PF07061.11 KLO20601.1 - 6.5e-18 64.6 1.4 8.6e-18 64.2 1.4 1.2 1 0 0 1 1 1 1 Swi5 BST2 PF16716.5 KLO20601.1 - 0.003 18.1 2.1 0.0042 17.6 0.7 1.7 1 1 0 2 2 2 1 Bone marrow stromal antigen 2 M16C_assoc PF08367.11 KLO20601.1 - 0.012 14.7 2.1 0.018 14.2 2.1 1.1 1 0 0 1 1 1 0 Peptidase M16C associated Lzipper-MIP1 PF14389.6 KLO20601.1 - 0.026 14.8 1.2 0.049 13.9 1.2 1.6 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF1912 PF08930.10 KLO20601.1 - 0.083 13.1 0.2 0.12 12.5 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1912) TMPIT PF07851.13 KLO20601.1 - 0.11 11.7 0.8 0.12 11.6 0.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein bZIP_2 PF07716.15 KLO20601.1 - 0.11 12.5 1.3 0.2 11.8 0.4 1.8 2 0 0 2 2 2 0 Basic region leucine zipper SIKE PF05769.11 KLO20602.1 - 4.3e-09 36.6 17.3 5.9e-07 29.6 11.0 2.4 1 1 0 2 2 2 2 SIKE family Atx10homo_assoc PF09759.9 KLO20602.1 - 0.031 14.3 1.4 0.074 13.1 0.1 2.2 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain YabA PF06156.13 KLO20602.1 - 0.11 13.1 9.8 1 10.1 1.6 3.5 3 0 0 3 3 3 0 Initiation control protein YabA Cnn_1N PF07989.11 KLO20602.1 - 0.15 12.3 10.8 1.2 9.3 7.8 3.1 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KLO20602.1 - 0.22 11.9 8.6 1.2 9.5 0.2 3.6 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Atg14 PF10186.9 KLO20602.1 - 0.24 10.5 7.9 0.51 9.4 7.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TACC_C PF05010.14 KLO20602.1 - 0.98 9.2 11.5 0.26 11.0 5.7 2.6 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DivIC PF04977.15 KLO20602.1 - 1.8 8.4 21.6 0.61 9.9 0.3 3.7 4 0 0 4 4 4 0 Septum formation initiator ABC_tran PF00005.27 KLO20603.1 - 8.5e-50 168.8 0.0 5e-24 85.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KLO20603.1 - 3.5e-24 85.5 37.3 2.1e-13 50.1 20.5 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KLO20603.1 - 3.6e-20 73.0 0.3 1.6e-06 28.1 0.0 4.5 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KLO20603.1 - 1e-06 29.4 0.0 0.0019 18.9 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) SMC_N PF02463.19 KLO20603.1 - 5.3e-06 26.0 1.1 0.039 13.4 0.1 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KLO20603.1 - 6.9e-06 26.7 0.7 0.067 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KLO20603.1 - 5.4e-05 23.2 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KLO20603.1 - 0.00077 19.2 1.1 0.17 11.7 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KLO20603.1 - 0.0008 19.2 0.0 3.7 7.1 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_27 PF13514.6 KLO20603.1 - 0.0013 18.4 0.2 0.28 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane PF01061.24 KLO20603.1 - 0.0064 15.9 40.8 0.071 12.5 15.0 3.8 3 1 0 3 3 3 2 ABC-2 type transporter AAA_30 PF13604.6 KLO20603.1 - 0.014 15.1 0.5 10 5.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KLO20603.1 - 0.02 15.2 0.2 14 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 KLO20603.1 - 0.033 13.8 0.4 4.1 7.0 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 KLO20603.1 - 0.046 13.7 0.1 7.6 6.4 0.0 2.8 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_16 PF13191.6 KLO20603.1 - 0.052 13.9 0.2 8.3 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Glutaredoxin PF00462.24 KLO20604.1 - 1e-09 38.4 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF3328 PF11807.8 KLO20604.1 - 0.19 11.5 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) BRO1 PF03097.18 KLO20605.1 - 2.5e-23 82.5 0.0 3.4e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain Vps5 PF09325.10 KLO20605.1 - 0.0032 17.1 0.1 0.0078 15.8 0.1 1.6 1 0 0 1 1 1 1 Vps5 C terminal like Nup96 PF12110.8 KLO20607.1 - 1.2e-78 264.2 0.0 1.9e-78 263.5 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Homeodomain PF00046.29 KLO20608.1 - 1.3e-17 63.3 2.8 2.4e-17 62.5 2.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KLO20608.1 - 3.2e-05 23.7 0.0 8.2e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain BrkDBD PF09607.10 KLO20608.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Brinker DNA-binding domain Tudor_FRX1 PF18336.1 KLO20608.1 - 0.17 11.8 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain Methyltransf_16 PF10294.9 KLO20609.1 - 3.7e-16 59.3 0.0 6.3e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KLO20609.1 - 6.3e-05 23.6 0.1 0.00023 21.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KLO20609.1 - 0.00049 20.8 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KLO20609.1 - 0.008 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KLO20609.1 - 0.012 15.1 0.1 0.052 12.9 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KLO20609.1 - 0.04 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KLO20609.1 - 0.18 11.3 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain zf-MYND PF01753.18 KLO20610.1 - 6.1e-07 29.4 17.7 1.6e-06 28.1 17.7 1.8 1 1 0 1 1 1 1 MYND finger Shisa PF13908.6 KLO20610.1 - 2.8 8.2 10.1 4.8 7.4 10.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator BNIP2 PF12496.8 KLO20611.1 - 0.11 13.0 0.7 0.12 12.8 0.7 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 TIP49 PF06068.13 KLO20612.1 - 6.3e-156 519.0 0.4 8.9e-156 518.5 0.4 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KLO20612.1 - 6.1e-23 80.7 0.4 4.5e-22 77.9 0.6 2.3 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KLO20612.1 - 8.9e-09 35.9 2.5 3.3e-06 27.6 0.0 3.2 3 2 1 4 4 4 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KLO20612.1 - 5.5e-07 29.5 0.1 0.00089 19.0 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KLO20612.1 - 2.2e-05 24.9 0.1 0.0001 22.7 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 KLO20612.1 - 0.0002 20.8 0.5 0.00037 19.9 0.5 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.14 KLO20612.1 - 0.00065 19.7 1.4 1 9.3 0.1 3.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KLO20612.1 - 0.0038 16.8 0.2 0.011 15.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KLO20612.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KLO20612.1 - 0.0072 16.6 0.1 0.7 10.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KLO20612.1 - 0.0087 15.5 1.5 0.74 9.2 0.2 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ERAP1_C PF11838.8 KLO20612.1 - 0.011 15.3 0.0 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 ERAP1-like C-terminal domain AAA_19 PF13245.6 KLO20612.1 - 0.016 15.5 6.1 0.09 13.1 0.7 3.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KLO20612.1 - 0.037 14.2 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KLO20612.1 - 0.048 13.9 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KLO20612.1 - 0.051 13.1 0.2 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Ribosomal_L2_C PF03947.18 KLO20613.1 - 1.1e-53 180.8 1.4 1.8e-53 180.1 0.6 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KLO20613.1 - 2.3e-23 82.0 0.4 4.8e-23 80.9 0.4 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF4611 PF15387.6 KLO20614.1 - 0.03 14.5 2.1 0.033 14.4 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Ku_C PF03730.14 KLO20614.1 - 0.088 13.5 0.6 0.11 13.2 0.6 1.2 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Baculo_PEP_C PF04513.12 KLO20615.1 - 0.0011 19.0 13.9 0.058 13.4 7.2 2.6 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KLO20615.1 - 0.0076 16.5 0.5 0.1 12.8 0.0 2.5 1 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) COG5 PF10392.9 KLO20615.1 - 0.021 15.0 0.2 0.084 13.0 0.1 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Ribosomal_L21e PF01157.18 KLO20617.1 - 4.3e-46 154.9 4.5 6.2e-46 154.4 4.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_replicase_B PF03431.13 KLO20617.1 - 0.0092 14.5 0.3 0.011 14.3 0.3 1.0 1 0 0 1 1 1 1 RNA replicase, beta-chain S4 PF01479.25 KLO20618.1 - 8.8e-11 41.4 1.7 8.8e-11 41.4 1.7 2.7 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KLO20618.1 - 1.7e-06 28.8 0.2 3.6e-06 27.8 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Dynactin PF12455.8 KLO20619.1 - 2.8e-90 302.5 5.3 2.8e-90 302.5 5.3 3.2 4 1 1 5 5 5 2 Dynein associated protein CAP_GLY PF01302.25 KLO20619.1 - 9.4e-23 80.0 0.6 3.7e-22 78.1 0.3 2.0 2 0 0 2 2 2 1 CAP-Gly domain Hist_deacetyl PF00850.19 KLO20620.1 - 1.8e-68 231.3 0.0 2.4e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain C2 PF00168.30 KLO20621.1 - 2.7e-24 85.4 0.0 7.8e-15 55.0 0.0 2.7 2 0 0 2 2 2 2 C2 domain V-SNARE_C PF12352.8 KLO20622.1 - 3.2e-16 59.3 2.7 3.2e-16 59.3 2.7 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KLO20622.1 - 0.0047 16.8 0.2 0.027 14.4 0.0 2.3 3 1 0 3 3 3 1 Sec20 TipAS PF07739.13 KLO20622.1 - 0.012 16.2 0.1 0.05 14.2 0.0 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain CK2S PF15011.6 KLO20622.1 - 0.018 14.9 2.1 0.085 12.7 0.3 2.6 2 1 1 3 3 3 0 Casein Kinase 2 substrate DUF4407 PF14362.6 KLO20622.1 - 0.028 13.8 1.4 0.043 13.2 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) End3 PF12761.7 KLO20622.1 - 0.041 14.1 2.7 0.059 13.5 1.3 1.9 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Med30 PF11315.8 KLO20622.1 - 0.042 14.1 1.1 0.34 11.1 0.0 2.3 2 1 0 2 2 2 0 Mediator complex subunit 30 DUF1664 PF07889.12 KLO20622.1 - 0.052 13.6 0.5 1.4 8.9 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CCDC-167 PF15188.6 KLO20622.1 - 0.083 13.2 1.7 6.5 7.2 0.6 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 PMC2NT PF08066.12 KLO20622.1 - 0.7 10.6 4.5 1.3 9.7 0.2 2.7 2 1 1 3 3 3 0 PMC2NT (NUC016) domain CorA PF01544.18 KLO20622.1 - 7.1 5.8 8.1 2.2 7.5 0.3 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF726 PF05277.12 KLO20625.1 - 3.3e-123 411.0 2.4 4.6e-123 410.5 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.20 KLO20625.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold SRP14 PF02290.15 KLO20626.1 - 3.5e-24 85.0 1.7 5e-24 84.5 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Ank_2 PF12796.7 KLO20627.1 - 2.4e-13 50.5 0.1 8.7e-11 42.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KLO20627.1 - 3.6e-13 48.4 0.1 6.4e-05 23.1 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KLO20627.1 - 1.8e-12 47.1 0.1 3.5e-05 24.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KLO20627.1 - 7e-12 45.6 0.2 7.7e-06 26.4 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KLO20627.1 - 1.1e-11 44.7 0.3 1.7e-05 25.0 0.2 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) tRNA-synt_His PF13393.6 KLO20628.1 - 1.5e-37 129.5 0.0 4.2e-34 118.2 0.0 2.3 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KLO20628.1 - 1.1e-08 35.1 0.1 2.9e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain ADH_N PF08240.12 KLO20631.1 - 3.1e-29 101.0 0.2 3.1e-29 101.0 0.2 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KLO20631.1 - 1.7e-11 44.2 0.5 5.3e-09 36.1 0.5 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KLO20631.1 - 0.00011 21.7 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain QRPTase_C PF01729.19 KLO20631.1 - 0.0066 16.2 0.0 0.015 15.1 0.0 1.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain Sacchrp_dh_NADP PF03435.18 KLO20631.1 - 0.032 14.5 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_31 PF13847.6 KLO20631.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L17 PF01196.19 KLO20633.1 - 7.1e-35 119.8 0.0 8.4e-35 119.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L17 PP-binding PF00550.25 KLO20634.1 - 7.3e-15 55.1 0.6 1.3e-14 54.3 0.6 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KLO20634.1 - 1.7e-06 28.2 0.1 2.1e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier hnRNP_Q_AcD PF18360.1 KLO20634.1 - 0.036 14.0 0.0 0.096 12.7 0.0 1.7 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain SGL PF08450.12 KLO20635.1 - 2e-68 230.7 0.0 2.3e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KLO20635.1 - 0.0021 18.2 0.0 0.0082 16.3 0.0 1.9 2 0 0 2 2 2 1 Arylesterase PQQ_2 PF13360.6 KLO20635.1 - 0.012 15.2 0.0 0.031 13.9 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain DUF4221 PF13970.6 KLO20635.1 - 0.13 11.8 0.0 11 5.5 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4221) NHL PF01436.21 KLO20635.1 - 0.16 12.1 0.3 14 5.9 0.0 3.0 3 0 0 3 3 3 0 NHL repeat Aminotran_1_2 PF00155.21 KLO20637.1 - 9.9e-91 304.6 0.0 1.1e-90 304.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_2 PF00152.20 KLO20638.1 - 2.1e-74 250.4 0.1 3.2e-74 249.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KLO20638.1 - 6.5e-05 22.8 0.1 0.00012 22.0 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FtsH_ext PF06480.15 KLO20638.1 - 0.0068 16.7 0.0 0.02 15.2 0.0 1.8 1 1 0 1 1 1 1 FtsH Extracellular tRNA-synt_2d PF01409.20 KLO20638.1 - 0.065 12.7 2.6 2.2 7.7 0.0 2.9 4 0 0 4 4 4 0 tRNA synthetases class II core domain (F) APC_u15 PF16636.5 KLO20638.1 - 8.9 6.8 14.9 0.68 10.4 3.6 2.6 1 1 1 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 Sortilin-Vps10 PF15902.5 KLO20639.1 - 1.1e-12 47.5 10.9 0.00022 20.1 0.0 6.0 4 2 1 5 5 5 4 Sortilin, neurotensin receptor 3, CBM_1 PF00734.18 KLO20639.1 - 1.7e-12 47.0 8.7 4.8e-12 45.6 8.7 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.20 KLO20639.1 - 1.6e-07 30.3 31.5 0.18 11.9 0.3 9.1 8 0 0 8 8 8 6 BNR/Asp-box repeat LRR_4 PF12799.7 KLO20640.1 - 2.9e-09 37.1 18.4 0.00064 20.1 0.1 7.4 6 2 3 9 9 9 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KLO20640.1 - 0.00065 19.6 17.6 5.2 7.4 0.0 8.3 9 0 0 9 9 9 3 Leucine Rich repeat LRR_8 PF13855.6 KLO20640.1 - 0.0008 19.1 14.3 0.028 14.2 0.4 5.8 4 3 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 KLO20640.1 - 0.073 13.7 11.0 78 4.4 0.0 7.2 8 0 0 8 8 8 0 Leucine Rich Repeat GGN PF15685.5 KLO20640.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Gametogenetin Vps51 PF08700.11 KLO20641.1 - 1.1e-10 41.4 1.0 3.9e-10 39.7 1.0 1.9 1 0 0 1 1 1 1 Vps51/Vps67 RE_XcyI PF09571.10 KLO20641.1 - 0.085 12.1 0.2 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 XcyI restriction endonuclease DUF4430 PF14478.6 KLO20642.1 - 0.0036 17.9 0.0 0.0067 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) CarboxypepD_reg PF13620.6 KLO20642.1 - 0.12 12.6 1.3 0.67 10.3 0.5 2.5 2 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain DUF1751 PF08551.10 KLO20643.1 - 6.2e-25 87.7 6.1 1.3e-24 86.6 6.1 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DUF1754 PF08555.10 KLO20644.1 - 1.9e-12 47.8 15.1 1.9e-12 47.8 15.1 1.5 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF5539 PF17693.1 KLO20644.1 - 0.023 14.3 0.2 0.025 14.2 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5539) DUF4407 PF14362.6 KLO20644.1 - 0.3 10.4 4.7 0.38 10.1 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Menin PF05053.13 KLO20644.1 - 1.5 7.1 8.9 1.7 6.9 8.9 1.0 1 0 0 1 1 1 0 Menin DUF3818 PF12825.7 KLO20644.1 - 1.6 7.7 5.1 2 7.3 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) FAM60A PF15396.6 KLO20644.1 - 1.7 8.6 11.0 2.1 8.3 11.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A UPF0560 PF10577.9 KLO20644.1 - 1.7 7.0 8.8 1.9 6.9 8.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 LRIF1 PF15741.5 KLO20644.1 - 3.8 5.9 14.2 4.6 5.6 14.2 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Macoilin PF09726.9 KLO20644.1 - 6.7 5.1 12.4 7.4 5.0 12.4 1.0 1 0 0 1 1 1 0 Macoilin family WSD PF15613.6 KLO20645.1 - 0.00061 20.2 0.2 0.0019 18.6 0.1 2.0 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF1192 PF06698.11 KLO20645.1 - 4.8 7.3 5.8 20 5.3 3.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Peptidase_M3 PF01432.20 KLO20646.1 - 5.1e-125 418.3 0.0 6.8e-125 417.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 KLO20646.1 - 0.13 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Effector protein Homeobox_KN PF05920.11 KLO20647.1 - 3.5e-12 46.0 0.1 7.7e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Mating_N PF12731.7 KLO20647.1 - 2.7e-06 27.4 1.1 6.8e-06 26.1 1.1 1.7 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeodomain PF00046.29 KLO20647.1 - 0.0022 17.8 0.0 0.0058 16.5 0.0 1.7 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 KLO20648.1 - 4.8e-15 55.1 2.7 1.4e-14 53.7 2.7 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KLO20648.1 - 2.1e-07 30.7 1.0 4.8e-07 29.6 1.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Phostensin_N PF13916.6 KLO20648.1 - 0.1 12.9 0.2 0.71 10.2 0.0 2.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Homez PF11569.8 KLO20648.1 - 0.12 11.9 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF2737 PF10930.8 KLO20648.1 - 0.14 11.8 0.1 0.33 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) HOCHOB PF17943.1 KLO20648.1 - 0.26 12.0 1.3 0.42 11.3 0.1 1.9 3 0 0 3 3 3 0 Homeobox-cysteine loop-homeobox Homeobox_KN PF05920.11 KLO20649.1 - 1.4e-14 53.6 0.1 3.8e-14 52.3 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KLO20649.1 - 2.2e-06 27.4 0.0 7.5e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 Homeodomain Mating_N PF12731.7 KLO20649.1 - 0.0091 16.1 0.2 0.03 14.4 0.2 1.8 1 0 0 1 1 1 1 Mating-type protein beta 1 Miga PF10265.9 KLO20649.1 - 2.6 6.9 6.1 1.2 8.0 3.7 1.7 2 0 0 2 2 2 0 Mitoguardin Homeodomain PF00046.29 KLO20650.1 - 1.2e-13 50.6 0.5 2.8e-13 49.5 0.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KLO20650.1 - 5.3e-09 35.8 1.8 7.9e-09 35.3 0.3 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 KLO20650.1 - 0.00042 19.7 0.0 0.00077 18.9 0.0 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Glyco_transf_8 PF01501.20 KLO20651.1 - 3.7e-20 72.6 1.1 1.1e-19 71.0 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KLO20651.1 - 0.1 12.0 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative MFS_1 PF07690.16 KLO20652.1 - 6.4e-43 147.0 34.0 1.1e-40 139.7 19.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KLO20652.1 - 2.2e-09 36.7 6.0 2.2e-09 36.7 6.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KLO20652.1 - 6.2e-05 22.0 3.0 0.14 11.0 0.0 2.5 1 1 1 2 2 2 2 MFS_1 like family TRI12 PF06609.13 KLO20652.1 - 8.1e-05 21.2 7.7 0.00013 20.6 7.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CPP1-like PF11833.8 KLO20652.1 - 0.11 12.2 4.3 0.34 10.6 4.3 1.8 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Apolipoprotein PF01442.18 KLO20654.1 - 1.9e-13 50.7 16.5 7.1e-12 45.6 8.7 2.1 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF5324 PF17258.2 KLO20654.1 - 2.1e-05 24.3 25.2 8.5e-05 22.3 11.0 3.0 1 1 1 2 2 2 2 Family of unknown function (DUF5324) MT0933_antitox PF14013.6 KLO20654.1 - 0.0036 17.6 19.1 3.7 7.9 1.1 5.3 3 1 1 4 4 4 3 MT0933-like antitoxin protein ISG65-75 PF11727.8 KLO20654.1 - 0.0041 16.4 5.5 0.0041 16.4 5.5 2.6 1 1 1 2 2 2 1 Invariant surface glycoprotein DUF883 PF05957.13 KLO20654.1 - 0.057 14.0 19.2 3 8.5 4.6 4.3 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Activator-TraM PF11657.8 KLO20654.1 - 0.12 12.2 9.7 0.26 11.1 1.7 3.1 2 1 1 3 3 3 0 Transcriptional activator TraM SNase PF00565.17 KLO20654.1 - 0.18 12.3 4.9 7.5 7.1 0.9 3.7 1 1 2 3 3 3 0 Staphylococcal nuclease homologue Phasin_2 PF09361.10 KLO20654.1 - 0.21 11.9 21.8 0.17 12.1 1.2 4.3 3 2 2 5 5 5 0 Phasin protein PhaP_Bmeg PF09602.10 KLO20654.1 - 0.36 10.7 2.7 0.68 9.9 0.2 2.4 1 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) YtxH PF12732.7 KLO20654.1 - 1.9 9.1 22.2 1.8e+04 -11.3 22.2 4.6 1 1 0 1 1 0 0 YtxH-like protein HSP9_HSP12 PF04119.12 KLO20654.1 - 2 8.8 17.0 0.58 10.6 0.2 4.7 2 2 1 4 4 4 0 Heat shock protein 9/12 dCache_2 PF08269.11 KLO20654.1 - 2.1 7.4 5.8 0.82 8.8 0.7 2.2 2 0 0 2 2 2 0 Cache domain Ku_C PF03730.14 KLO20654.1 - 7.9 7.2 10.9 3.3 8.5 0.3 3.2 2 2 1 3 3 3 0 Ku70/Ku80 C-terminal arm ABC1 PF03109.16 KLO20655.1 - 5.9e-21 74.8 0.0 9.1e-13 48.4 0.0 2.4 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 KLO20655.1 - 0.056 13.4 0.1 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family PX PF00787.24 KLO20658.1 - 7.9e-23 80.6 0.2 1.7e-22 79.5 0.2 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KLO20658.1 - 1.4e-06 28.0 4.3 3.5e-05 23.5 1.7 2.3 2 1 0 2 2 2 2 Vps5 C terminal like PCRF PF03462.18 KLO20658.1 - 0.033 14.0 1.6 0.077 12.8 1.6 1.6 1 0 0 1 1 1 0 PCRF domain PEP-utilisers_N PF05524.13 KLO20658.1 - 0.052 13.7 0.3 0.13 12.4 0.3 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal RNA_pol_Rpb2_6 PF00562.28 KLO20659.1 - 3.9e-126 421.3 0.1 5.3e-126 420.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KLO20659.1 - 1.4e-67 227.1 0.0 2e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KLO20659.1 - 1.4e-47 161.8 0.1 4.2e-47 160.2 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KLO20659.1 - 7.7e-33 112.8 0.1 1.8e-32 111.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KLO20659.1 - 2.7e-26 91.6 2.3 1e-25 89.8 2.3 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KLO20659.1 - 8.2e-26 90.0 0.1 2e-25 88.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KLO20659.1 - 3.6e-23 81.9 0.2 1.2e-22 80.2 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Lung_7-TM_R PF06814.13 KLO20660.1 - 2e-56 191.4 17.5 2.4e-56 191.1 17.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4234 PF14018.6 KLO20660.1 - 2 8.6 7.1 1.6 8.9 3.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) BLACT_WH PF17778.1 KLO20664.1 - 0.08 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain tRNA-synt_2b PF00587.25 KLO20667.1 - 2e-25 89.8 0.0 2.9e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KLO20667.1 - 1.2e-07 31.9 0.1 1.9e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TSC22 PF01166.18 KLO20667.1 - 0.041 14.2 0.1 0.078 13.3 0.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Trimer_CC PF08954.11 KLO20667.1 - 0.078 12.5 1.3 0.11 12.1 0.2 1.8 2 0 0 2 2 2 0 Trimerisation motif Rep_fac_C PF08542.11 KLO20668.1 - 8e-26 90.3 0.0 1.9e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KLO20668.1 - 1.4e-12 47.7 0.1 3.2e-10 40.0 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 KLO20668.1 - 9.8e-12 45.4 0.1 1.9e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KLO20668.1 - 3.5e-07 30.8 0.0 6.3e-05 23.4 0.0 2.9 1 1 2 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KLO20668.1 - 7.9e-07 29.2 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KLO20668.1 - 2.4e-06 27.9 0.0 0.0009 19.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KLO20668.1 - 3.5e-05 23.6 0.0 8.6e-05 22.3 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KLO20668.1 - 3.5e-05 23.7 0.0 7.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KLO20668.1 - 0.00014 21.7 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.13 KLO20668.1 - 0.00097 19.0 0.1 0.0016 18.2 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KLO20668.1 - 0.0012 18.3 0.0 0.016 14.6 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KLO20668.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain MeaB PF03308.16 KLO20668.1 - 0.0024 16.9 0.0 0.0057 15.7 0.0 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KLO20668.1 - 0.0046 16.7 0.0 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KLO20668.1 - 0.006 16.5 0.1 0.02 14.8 0.1 1.8 1 1 1 2 2 2 1 NTPase AAA_assoc_2 PF16193.5 KLO20668.1 - 0.0078 16.5 0.1 0.033 14.5 0.0 2.2 2 1 0 2 2 1 1 AAA C-terminal domain AAA_11 PF13086.6 KLO20668.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KLO20668.1 - 0.025 14.9 0.1 0.17 12.3 0.1 2.4 2 1 0 2 2 2 0 RNA helicase TniB PF05621.11 KLO20668.1 - 0.03 13.7 0.0 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 KLO20668.1 - 0.037 14.3 0.3 0.14 12.5 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KLO20668.1 - 0.039 14.0 0.0 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KLO20668.1 - 0.076 12.7 0.1 0.19 11.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KLO20668.1 - 0.094 12.3 0.1 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain YflT PF11181.8 KLO20668.1 - 0.11 13.0 0.0 0.32 11.5 0.0 1.7 2 0 0 2 2 1 0 Heat induced stress protein YflT DEAD PF00270.29 KLO20668.1 - 0.13 12.0 0.1 1.2 8.9 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.6 KLO20668.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KLO20668.1 - 0.15 12.6 0.1 0.4 11.2 0.1 1.7 1 1 0 1 1 1 0 ABC transporter KTI12 PF08433.10 KLO20668.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 VHS PF00790.19 KLO20669.1 - 1.4e-26 93.0 0.1 4.4e-26 91.4 0.0 1.8 2 1 0 2 2 2 1 VHS domain GAT PF03127.14 KLO20669.1 - 1.3e-06 28.6 2.4 4.2e-06 27.0 2.0 2.2 2 0 0 2 2 2 1 GAT domain ALMT PF11744.8 KLO20669.1 - 3.1 6.5 5.7 4.6 6.0 5.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter MDM10 PF12519.8 KLO20669.1 - 9.2 5.0 8.0 13 4.5 8.0 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 ParA PF10609.9 KLO20670.1 - 2.8e-61 207.1 0.0 3.4e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase RRM_1 PF00076.22 KLO20673.1 - 3e-15 55.8 0.0 5.2e-07 29.4 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KLO20673.1 - 0.024 14.8 0.1 3.5 7.8 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif BRAP2 PF07576.12 KLO20673.1 - 0.046 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 RNA_pol_Rpb6 PF01192.22 KLO20674.1 - 1.4e-15 56.9 0.1 2.3e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Ribonuclease_T2 PF00445.18 KLO20675.1 - 2.1e-36 125.9 0.0 2.8e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Myb_DNA-bind_7 PF15963.5 KLO20678.1 - 7.7e-20 70.6 0.1 2.7e-19 68.8 0.1 2.0 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KLO20678.1 - 1e-07 32.1 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KLO20678.1 - 0.0027 17.9 0.0 0.0058 16.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2701 PF10857.8 KLO20679.1 - 0.16 12.0 0.3 0.48 10.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) SURF1 PF02104.15 KLO20680.1 - 4.1e-42 144.4 0.0 5e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 SURF1 family ANTH PF07651.16 KLO20681.1 - 4.3e-74 249.0 1.5 1.3e-72 244.1 0.0 3.0 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 KLO20681.1 - 9.1e-55 185.1 11.7 9.1e-55 185.1 11.7 5.4 4 1 1 6 6 6 1 I/LWEQ domain ENTH PF01417.20 KLO20681.1 - 0.0036 17.4 0.1 0.059 13.4 0.0 3.0 2 0 0 2 2 2 1 ENTH domain FAA_hydro_N_2 PF18288.1 KLO20681.1 - 0.17 12.4 1.8 1.2 9.7 1.2 2.9 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 EthD PF07110.11 KLO20683.1 - 1e-08 36.2 0.6 0.0025 18.9 0.1 2.4 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.6 KLO20683.1 - 6.1e-07 29.8 0.1 0.0078 16.7 0.1 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4286) Mvb12 PF09452.10 KLO20683.1 - 0.054 13.9 0.5 1 9.8 0.0 2.7 3 0 0 3 3 3 0 ESCRT-I subunit Mvb12 Ion_trans PF00520.31 KLO20684.1 - 7.6e-05 22.0 4.6 0.00011 21.6 4.6 1.1 1 0 0 1 1 1 1 Ion transport protein SHP PF03579.13 KLO20684.1 - 0.24 11.4 1.7 0.64 10.0 0.1 2.3 2 1 1 3 3 3 0 Small hydrophobic protein CWC25 PF12542.8 KLO20685.1 - 2.3e-23 83.0 0.1 2.3e-23 83.0 0.1 3.9 2 2 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 KLO20685.1 - 2.9e-14 53.0 12.6 2.9e-14 53.0 12.6 5.4 5 1 1 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF1754 PF08555.10 KLO20685.1 - 2.7 8.9 32.7 0.037 14.8 17.8 3.1 2 1 1 3 3 3 0 Eukaryotic family of unknown function (DUF1754) Oxidored_FMN PF00724.20 KLO20688.1 - 1.7e-54 185.4 0.0 2.3e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family p450 PF00067.22 KLO20689.1 - 1.9e-80 270.9 0.0 1.7e-79 267.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.19 KLO20690.1 - 1.1e-17 64.0 0.0 4.4e-09 35.7 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KLO20690.1 - 2e-15 57.0 0.0 4.9e-15 55.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KLO20690.1 - 3.2e-12 46.7 0.0 5.3e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KLO20690.1 - 1.5e-10 40.7 0.0 7.9e-09 35.0 0.0 2.7 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KLO20690.1 - 1.1e-06 28.4 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KLO20690.1 - 4.4e-05 23.7 0.1 0.00015 22.0 0.0 2.0 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KLO20690.1 - 0.00021 20.5 0.0 0.016 14.4 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KLO20690.1 - 0.0026 17.2 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KLO20690.1 - 0.021 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.20 KLO20690.1 - 0.038 14.0 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3591 PF12157.8 KLO20695.1 - 1.4e-188 627.0 1.5 2.6e-188 626.2 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 KLO20695.1 - 7.6e-05 22.5 3.1 0.00017 21.4 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle TFIIF_beta PF02270.15 KLO20695.1 - 0.0019 18.3 0.1 0.0041 17.2 0.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain BCA_ABC_TP_C PF12399.8 KLO20695.1 - 0.11 12.4 1.5 0.25 11.3 1.5 1.6 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter zf-CCHC PF00098.23 KLO20695.1 - 0.4 10.8 3.4 0.71 10.1 3.4 1.4 1 0 0 1 1 1 0 Zinc knuckle PCIF1_WW PF12237.8 KLO20696.1 - 0.1 12.2 0.3 0.23 11.1 0.3 1.5 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain DUF2630 PF10944.8 KLO20696.1 - 0.11 12.9 0.5 0.28 11.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) PAP2 PF01569.21 KLO20698.1 - 1.1e-14 54.3 4.5 1.1e-14 54.3 4.5 1.5 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 KLO20698.1 - 0.00027 21.1 0.2 0.0029 17.7 0.0 2.1 2 0 0 2 2 2 1 Divergent PAP2 family UbiA PF01040.18 KLO20698.1 - 0.11 11.7 6.1 0.21 10.8 2.5 2.2 2 0 0 2 2 2 0 UbiA prenyltransferase family PgaD PF13994.6 KLO20698.1 - 6.3 6.9 6.8 0.47 10.5 0.6 2.1 2 1 0 2 2 2 0 PgaD-like protein Rhodanese PF00581.20 KLO20699.1 - 1.2e-06 29.0 0.0 2.3e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain SIR2 PF02146.17 KLO20700.1 - 4.4e-33 114.7 0.0 2.7e-32 112.1 0.0 2.1 1 1 0 1 1 1 1 Sir2 family Asparaginase PF00710.20 KLO20700.1 - 0.045 13.3 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 Asparaginase, N-terminal EF-hand_6 PF13405.6 KLO20701.1 - 7.6e-13 47.3 0.9 1.8e-05 24.3 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KLO20701.1 - 1.2e-11 43.2 6.8 1.1e-05 24.6 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KLO20701.1 - 2e-11 44.2 6.3 7.5e-09 35.9 0.9 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KLO20701.1 - 1.1e-07 31.0 2.4 0.0023 17.3 0.6 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KLO20701.1 - 0.0011 18.7 8.4 0.0095 15.8 0.1 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 KLO20701.1 - 0.014 15.7 0.0 3.7 8.0 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain LRR_6 PF13516.6 KLO20702.1 - 2.2e-05 24.1 14.5 1.7 8.9 0.0 6.7 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 KLO20702.1 - 0.008 16.6 10.3 21 5.7 2.9 6.0 6 1 1 7 7 7 2 Leucine Rich repeats (2 copies) TFIIA PF03153.13 KLO20702.1 - 1 9.3 11.4 1.4 8.8 11.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_1 PF00560.33 KLO20702.1 - 2.9 8.8 6.9 2.1e+02 3.2 1.4 5.5 6 1 0 6 6 6 0 Leucine Rich Repeat NOA36 PF06524.12 KLO20702.1 - 3.1 7.0 11.8 4.5 6.5 11.8 1.2 1 0 0 1 1 1 0 NOA36 protein PBP PF01161.20 KLO20704.1 - 6e-15 55.7 0.3 1.2e-14 54.7 0.3 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein F-box-like PF12937.7 KLO20705.1 - 4.4e-05 23.3 1.2 0.0001 22.1 1.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KLO20705.1 - 0.0074 16.1 0.5 0.023 14.6 0.5 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KLO20706.1 - 0.00087 19.1 0.0 0.0026 17.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like FNIP PF05725.12 KLO20706.1 - 0.72 10.1 6.4 1.4 9.1 0.4 4.0 5 0 0 5 5 5 0 FNIP Repeat zf-C2H2 PF00096.26 KLO20708.1 - 1.6e-07 31.4 21.1 0.00031 21.0 2.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KLO20708.1 - 2.7e-06 27.5 0.5 0.00077 19.7 0.6 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KLO20708.1 - 0.0013 19.1 7.7 0.0025 18.2 0.7 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KLO20708.1 - 0.0016 18.8 3.9 0.0016 18.8 3.9 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KLO20708.1 - 0.0047 17.7 1.8 0.0047 17.7 1.8 3.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KLO20708.1 - 0.0098 15.9 1.0 0.0098 15.9 1.0 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger DUF2526 PF10735.9 KLO20708.1 - 0.093 12.9 0.2 0.37 11.0 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) FOXP-CC PF16159.5 KLO20708.1 - 0.38 11.4 16.4 0.091 13.4 0.8 3.3 1 1 2 3 3 3 0 FOXP coiled-coil domain Methyltransf_25 PF13649.6 KLO20709.1 - 0.0023 18.6 0.0 1.4 9.6 0.0 2.5 3 0 0 3 3 3 2 Methyltransferase domain QLQ PF08880.11 KLO20709.1 - 0.16 11.8 0.2 1.7 8.5 0.1 2.4 2 0 0 2 2 2 0 QLQ Methyltransf_25 PF13649.6 KLO20710.1 - 0.014 16.1 0.0 1.4 9.7 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 KLO20711.1 - 1.2e-47 161.9 0.1 1.6e-47 161.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KLO20711.1 - 1.7e-31 109.6 0.0 2.1e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KLO20711.1 - 1.6e-08 34.3 0.0 3.2e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KLO20711.1 - 2.4e-05 24.3 0.1 4.8e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KLO20711.1 - 8.5e-05 22.1 0.0 0.00017 21.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KLO20711.1 - 0.041 13.3 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PA28_beta PF02252.18 KLO20712.1 - 1.1e-55 187.3 1.5 2e-55 186.5 1.5 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 KLO20712.1 - 5.8e-08 32.7 0.5 1.2e-07 31.6 0.5 1.5 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit FAM180 PF15173.6 KLO20712.1 - 0.011 15.8 0.0 0.066 13.2 0.0 2.3 3 0 0 3 3 3 0 FAM180 family CAF1C_H4-bd PF12265.8 KLO20713.1 - 5.9e-16 58.5 0.3 1.1e-14 54.4 0.0 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KLO20713.1 - 5.6e-15 55.5 11.1 2.8e-05 24.8 0.1 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat NOA36 PF06524.12 KLO20713.1 - 2.6 7.3 4.7 4.1 6.6 4.7 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KLO20713.1 - 7.4 7.0 10.8 0.22 11.9 4.3 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MAPEG PF01124.18 KLO20714.1 - 3.7e-22 78.6 0.2 4.4e-22 78.4 0.2 1.0 1 0 0 1 1 1 1 MAPEG family MAPEG PF01124.18 KLO20715.1 - 1.1e-20 73.8 1.1 1.2e-20 73.7 1.1 1.0 1 0 0 1 1 1 1 MAPEG family UL73_N PF12522.8 KLO20716.1 - 2.1 8.2 16.4 1.6 8.6 2.9 3.4 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal GARS_A PF01071.19 KLO20720.1 - 3.6e-80 268.3 0.0 6.6e-80 267.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KLO20720.1 - 6.5e-37 127.1 0.0 2.8e-36 125.0 0.0 2.1 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KLO20720.1 - 1.6e-33 115.3 0.1 4.8e-33 113.8 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KLO20720.1 - 2.1e-28 98.4 2.0 5.1e-28 97.2 2.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KLO20720.1 - 2.4e-14 53.7 1.5 2.4e-13 50.5 1.6 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 KLO20720.1 - 1.2e-06 28.2 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KLO20720.1 - 0.034 14.2 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain zf-CCCH_4 PF18044.1 KLO20721.1 - 1e-07 31.6 17.1 0.00059 19.6 3.2 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Ank_5 PF13857.6 KLO20721.1 - 1.4e-06 28.5 0.0 5.6e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KLO20721.1 - 2.4e-06 28.0 0.0 4.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KLO20721.1 - 1.1e-05 25.9 0.0 2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Torus PF16131.5 KLO20721.1 - 2.8e-05 24.7 0.7 0.00053 20.7 0.1 2.4 2 0 0 2 2 2 1 Torus domain Ank_3 PF13606.6 KLO20721.1 - 4.1e-05 23.6 0.1 0.0026 18.1 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat zf-CCCH_2 PF14608.6 KLO20721.1 - 0.0001 22.6 10.0 0.0001 22.6 10.0 2.5 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 KLO20721.1 - 0.00035 20.5 4.2 0.00035 20.5 4.2 3.0 4 0 0 4 4 4 2 Zinc finger domain Ank PF00023.30 KLO20721.1 - 0.0033 17.8 0.1 0.01 16.2 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH PF00642.24 KLO20721.1 - 0.012 15.5 13.8 0.11 12.4 2.4 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NAD_Gly3P_dh_C PF07479.14 KLO20722.1 - 1.3e-46 158.4 0.3 2e-46 157.8 0.3 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KLO20722.1 - 6.2e-34 117.2 0.0 1.4e-33 116.1 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KLO20722.1 - 7.9e-07 28.8 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KLO20722.1 - 2e-06 28.3 0.0 9.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KLO20722.1 - 0.0037 17.4 0.0 0.01 16.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KLO20722.1 - 0.085 12.9 0.0 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SNARE PF05739.19 KLO20723.1 - 2.1e-13 50.0 0.1 4.5e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KLO20723.1 - 2.4e-06 26.6 0.0 5.8e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KLO20723.1 - 4e-05 23.4 10.4 0.00017 21.3 0.7 2.6 2 1 1 3 3 3 2 Syntaxin Syntaxin-18_N PF10496.9 KLO20723.1 - 0.00087 19.5 0.4 0.0059 16.8 0.1 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SlyX PF04102.12 KLO20723.1 - 0.047 14.3 8.0 0.38 11.4 0.8 3.2 2 1 0 2 2 2 0 SlyX FlaC_arch PF05377.11 KLO20723.1 - 0.13 12.7 1.8 2.2 8.7 0.1 3.0 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 KLO20723.1 - 0.13 12.5 0.3 0.13 12.5 0.3 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 KLO20723.1 - 2.6 8.6 10.5 0.23 12.0 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 KLO20723.1 - 2.9 8.4 9.7 0.8 10.2 0.9 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PRKG1_interact PF15898.5 KLO20723.1 - 5.1 8.1 7.1 1.2 10.1 1.8 2.4 3 0 0 3 3 2 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 KLO20723.1 - 5.2 7.1 8.2 4.4 7.3 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 KLO20723.1 - 7.7 7.1 8.4 1.1 9.8 0.2 2.8 3 1 0 3 3 3 0 Spectrin repeat RRM_1 PF00076.22 KLO20724.1 - 5e-10 39.1 0.0 9.6e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PcfK PF14058.6 KLO20724.1 - 4.8 7.5 12.3 1.3 9.3 5.9 2.4 2 0 0 2 2 2 0 PcfK-like protein Pal1 PF08316.11 KLO20725.1 - 0.99 10.2 0.0 0.99 10.2 0.0 4.3 4 1 0 4 4 4 0 Pal1 cell morphology protein AMP-binding PF00501.28 KLO20729.1 - 1.2e-88 297.6 0.0 1.5e-88 297.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KLO20729.1 - 1.2e-13 51.8 1.2 2.6e-13 50.8 0.3 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Med7 PF05983.11 KLO20730.1 - 3.4e-50 170.8 0.4 4.3e-50 170.5 0.4 1.1 1 0 0 1 1 1 1 MED7 protein HAUS6_N PF14661.6 KLO20730.1 - 0.038 13.6 1.3 0.05 13.2 0.3 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus P34-Arc PF04045.14 KLO20731.1 - 6.5e-109 363.2 0.0 7.9e-109 363.0 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Tweety PF04906.13 KLO20731.1 - 0.021 13.5 0.0 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 Tweety PCI PF01399.27 KLO20732.1 - 5.3e-17 62.3 0.0 3.3e-16 59.7 0.0 2.3 3 1 0 3 3 3 1 PCI domain RPN5_C PF18098.1 KLO20732.1 - 4.6e-05 23.4 1.7 6.9e-05 22.9 0.7 1.9 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain TPR_20 PF14561.6 KLO20732.1 - 0.36 11.2 2.3 3.4 8.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Drc1-Sld2 PF11719.8 KLO20733.1 - 3.9e-15 56.4 11.8 3.9e-15 56.4 11.8 2.4 1 1 1 3 3 3 1 DNA replication and checkpoint protein CPSF100_C PF13299.6 KLO20733.1 - 0.27 11.4 6.4 0.15 12.2 0.3 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal LRR_4 PF12799.7 KLO20734.1 - 0.088 13.3 2.4 5 7.7 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 KLO20736.1 - 9.8e-50 169.4 0.0 1.4e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KLO20736.1 - 3.1e-30 105.3 0.0 3.9e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KLO20736.1 - 0.0042 16.5 0.0 0.0079 15.5 0.0 1.4 2 0 0 2 2 2 1 Kinase-like FHA PF00498.26 KLO20736.1 - 0.025 14.9 0.1 0.071 13.5 0.1 1.8 1 1 0 1 1 1 0 FHA domain ANAPC10 PF03256.16 KLO20736.1 - 0.091 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Esterase PF00756.20 KLO20737.1 - 4.3e-40 137.9 0.0 5.2e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KLO20737.1 - 0.00098 18.1 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KLO20737.1 - 0.0023 17.4 0.2 0.0034 16.9 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KLO20737.1 - 0.047 13.0 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KLO20738.1 - 2.1e-08 34.2 1.0 2.5e-08 33.9 0.1 1.6 2 0 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 KLO20738.1 - 8.6e-06 25.8 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KLO20738.1 - 0.00041 20.1 0.1 0.0024 17.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KLO20738.1 - 0.00098 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KLO20738.1 - 0.0041 17.7 0.0 0.0041 17.7 0.0 2.5 1 1 0 2 2 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KLO20738.1 - 0.0044 16.5 0.1 0.01 15.4 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF915 PF06028.11 KLO20738.1 - 0.0085 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 KLO20738.1 - 0.028 13.6 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 KLO20738.1 - 0.047 13.0 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PPV_E2_C PF00511.17 KLO20738.1 - 0.087 13.0 0.6 0.26 11.5 0.6 1.8 1 0 0 1 1 1 0 E2 (early) protein, C terminal UPF0227 PF05728.12 KLO20738.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Kelch_5 PF13854.6 KLO20739.1 - 1.8e-34 117.2 4.2 1.8e-07 31.0 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KLO20739.1 - 7.5e-33 112.2 20.2 1.5e-11 44.3 0.0 7.2 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KLO20739.1 - 5.8e-31 106.3 7.3 1.1e-09 38.2 0.1 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KLO20739.1 - 1.7e-24 85.3 11.0 2.5e-07 30.7 0.2 6.4 3 2 3 6 6 6 4 Kelch motif Kelch_1 PF01344.25 KLO20739.1 - 1.2e-23 82.4 10.1 9.8e-09 34.7 0.2 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KLO20739.1 - 2.1e-21 75.0 12.0 5.3e-08 32.5 0.4 6.5 6 1 0 6 6 6 4 Kelch motif DUF1668 PF07893.13 KLO20739.1 - 0.021 14.2 0.1 0.047 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) RAG2 PF03089.14 KLO20739.1 - 0.023 13.7 0.6 1.5 7.7 0.0 3.3 1 1 0 3 3 3 0 Recombination activating protein 2 Kelch_4 PF13418.6 KLO20740.1 - 7.9e-31 105.8 13.4 9.1e-09 35.2 1.5 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KLO20740.1 - 1.5e-29 101.6 12.3 3.1e-07 30.5 0.2 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KLO20740.1 - 1.6e-28 98.0 5.3 1.4e-09 37.4 1.4 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KLO20740.1 - 1.7e-28 98.1 8.7 2.7e-06 27.2 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KLO20740.1 - 1.5e-23 82.2 11.3 1.8e-09 37.5 1.2 6.4 4 2 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KLO20740.1 - 7.2e-22 76.5 8.4 1.9e-07 30.8 0.7 6.5 6 0 0 6 6 6 5 Kelch motif S1 PF00575.23 KLO20741.1 - 8.5e-49 163.8 30.7 1.3e-10 41.5 0.5 10.1 9 0 0 9 9 9 8 S1 RNA binding domain TPR_19 PF14559.6 KLO20741.1 - 7e-05 23.3 0.0 0.71 10.4 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat Suf PF05843.14 KLO20741.1 - 0.00012 22.1 0.5 0.00012 22.1 0.5 5.0 2 1 3 5 5 5 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 KLO20741.1 - 0.0013 17.9 11.8 0.023 13.8 4.8 3.1 2 1 1 3 3 3 2 NRDE-2, necessary for RNA interference PCB_OB PF17092.5 KLO20741.1 - 0.0082 16.9 2.5 12 6.7 0.1 5.6 6 0 0 6 6 6 1 Penicillin-binding protein OB-like domain S1_2 PF13509.6 KLO20741.1 - 0.03 14.4 0.9 19 5.4 0.0 4.8 5 1 0 5 5 5 0 S1 domain TPR_12 PF13424.6 KLO20741.1 - 0.033 14.5 0.4 1.3 9.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KLO20741.1 - 0.038 14.8 0.0 1.1e+02 4.1 0.0 4.6 3 2 2 5 5 5 0 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 KLO20741.1 - 0.05 13.5 0.7 3 7.9 0.0 4.2 5 0 0 5 5 5 0 RNase II-type exonuclease C-terminal S1 domain SF3A2 PF16835.5 KLO20742.1 - 2.2e-36 124.1 0.1 3.2e-36 123.6 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KLO20742.1 - 2e-06 28.0 0.7 2e-06 28.0 0.7 2.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KLO20742.1 - 0.043 13.8 0.1 0.063 13.2 0.1 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein MMR_HSR1 PF01926.23 KLO20743.1 - 1.6e-17 63.6 0.1 9.7e-15 54.7 0.0 2.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KLO20743.1 - 3.7e-06 26.9 0.1 0.0017 18.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KLO20743.1 - 6.4e-06 25.8 0.1 4.3e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 KLO20743.1 - 0.0003 20.2 0.1 0.0011 18.3 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 KLO20743.1 - 0.021 14.9 0.1 0.061 13.4 0.1 1.8 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.6 KLO20743.1 - 0.17 12.3 0.9 8.2 6.8 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain Cellulase PF00150.18 KLO20744.1 - 4.8e-44 150.9 0.0 6e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TOBE_3 PF12857.7 KLO20744.1 - 0.12 12.4 0.0 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 TOBE-like domain CBM_1 PF00734.18 KLO20744.1 - 0.31 11.1 2.5 0.84 9.6 2.5 1.7 1 0 0 1 1 1 0 Fungal cellulose binding domain Complex1_LYR PF05347.15 KLO20745.1 - 4.2e-05 23.5 4.5 0.00015 21.7 4.2 2.1 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Sec8_exocyst PF04048.14 KLO20746.1 - 1.9e-34 118.6 1.2 3.4e-34 117.8 0.5 1.8 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KLO20746.1 - 8.7e-06 25.2 0.4 2.1e-05 23.9 0.4 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex LIDHydrolase PF10230.9 KLO20747.1 - 4.4e-41 141.2 0.0 5.3e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KLO20747.1 - 9.1e-05 23.2 0.2 0.00012 22.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KLO20747.1 - 0.00014 21.3 0.0 0.00017 20.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KLO20747.1 - 0.066 13.1 0.1 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase DUF900 PF05990.12 KLO20747.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Pkinase_Tyr PF07714.17 KLO20748.1 - 1.3e-50 172.1 0.0 3.3e-50 170.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KLO20748.1 - 1.3e-39 136.2 0.0 2.3e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Fve PF09259.11 KLO20748.1 - 3.3e-25 88.4 0.0 8.8e-25 87.0 0.0 1.7 2 0 0 2 2 2 1 Fungal immunomodulatory protein Fve RIO1 PF01163.22 KLO20748.1 - 3.1e-05 23.7 0.0 6.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family BfiI_DBD PF18243.1 KLO20748.1 - 0.0013 18.3 0.1 0.0031 17.1 0.1 1.6 1 0 0 1 1 1 1 Metal-independent restriction enzyme BfiI DNA binding domain LMBR1 PF04791.16 KLO20748.1 - 0.13 11.1 1.3 0.19 10.6 1.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF5621 PF18532.1 KLO20748.1 - 0.25 11.2 1.6 0.44 10.5 0.7 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF5621) HTH_24 PF13412.6 KLO20748.1 - 0.51 10.0 2.0 2.2 7.9 0.1 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding DUF2203 PF09969.9 KLO20748.1 - 0.7 10.6 3.5 3.9 8.2 0.7 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) SNF2_N PF00176.23 KLO20749.1 - 1.6e-72 244.2 0.0 4.5e-72 242.7 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO20749.1 - 2.5e-13 50.3 0.0 6.7e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KLO20749.1 - 0.00082 19.3 5.9 0.0019 18.1 5.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KLO20749.1 - 0.53 10.2 7.0 1.3 8.9 7.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KLO20749.1 - 4.9 6.4 8.2 3.4 7.0 5.0 2.2 1 1 1 2 2 2 0 Rtf2 RING-finger dsrm PF00035.26 KLO20751.1 - 2.5e-10 40.9 0.3 4.6e-10 40.1 0.3 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KLO20751.1 - 7.6e-09 35.8 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KLO20751.1 - 0.00015 22.3 0.0 0.00033 21.2 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain SNF2_N PF00176.23 KLO20752.1 - 7.7e-56 189.3 1.4 1.2e-55 188.7 1.4 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KLO20752.1 - 1.7e-19 70.2 0.1 6.5e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KLO20752.1 - 1.1e-16 60.9 0.5 2.4e-16 59.7 0.5 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 KLO20752.1 - 8.8e-07 28.7 1.3 0.0044 16.9 0.0 3.6 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain zf-PHD-like PF15446.6 KLO20752.1 - 1.1e-05 25.1 12.8 0.0006 19.5 0.3 3.1 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain ResIII PF04851.15 KLO20752.1 - 0.00018 21.6 0.7 0.003 17.6 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KLO20752.1 - 0.043 13.0 0.1 0.1 11.8 0.1 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Enkurin PF13864.6 KLO20752.1 - 0.33 11.4 7.1 0.096 13.1 1.1 2.9 2 0 0 2 2 2 0 Calmodulin-binding PHD_4 PF16866.5 KLO20752.1 - 4.7 7.4 13.4 1.3 9.1 0.9 3.8 3 0 0 3 3 3 0 PHD-finger Zn_clus PF00172.18 KLO20753.1 - 1.1e-07 31.8 11.1 2.1e-07 31.0 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KLO20753.1 - 0.00018 20.6 0.1 0.00058 19.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain ABC_membrane PF00664.23 KLO20754.1 - 1.5e-72 244.5 28.1 1.5e-38 133.0 12.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KLO20754.1 - 2.7e-55 186.6 0.0 5.9e-31 107.8 0.1 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 KLO20754.1 - 3.3e-06 27.6 0.1 0.1 13.0 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KLO20754.1 - 3.9e-06 26.4 5.8 0.0048 16.4 1.3 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KLO20754.1 - 9.2e-06 25.7 1.0 0.074 13.1 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KLO20754.1 - 7.2e-05 22.4 1.2 0.15 11.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KLO20754.1 - 0.0001 22.2 3.0 0.056 13.3 0.1 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_21 PF13304.6 KLO20754.1 - 0.00025 21.0 2.1 0.24 11.2 0.1 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KLO20754.1 - 0.00028 20.7 0.0 0.29 10.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain Roc PF08477.13 KLO20754.1 - 0.0043 17.3 0.4 2 8.7 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KLO20754.1 - 0.0052 17.3 0.3 1.1 9.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KLO20754.1 - 0.0095 15.7 2.4 20 4.9 0.2 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KLO20754.1 - 0.0098 16.0 3.7 0.73 9.9 0.4 2.5 2 0 0 2 2 2 1 Dynamin family AAA_7 PF12775.7 KLO20754.1 - 0.012 15.2 0.4 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KLO20754.1 - 0.022 14.3 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KLO20754.1 - 0.029 13.6 0.5 2.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 KLO20754.1 - 0.074 13.4 0.2 22 5.5 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_22 PF13401.6 KLO20754.1 - 0.091 13.0 3.4 15 5.9 0.1 3.2 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 KLO20754.1 - 0.12 12.4 0.8 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KLO20754.1 - 0.15 11.8 0.9 19 5.0 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein NACHT PF05729.12 KLO20754.1 - 0.16 11.9 1.3 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 KLO20754.1 - 0.23 12.0 0.6 30 5.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 KLO20754.1 - 0.36 10.4 1.9 1.7 8.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KLO20754.1 - 0.48 10.1 3.7 19 4.9 0.1 2.9 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KLO20754.1 - 1.3 9.1 4.0 0.91 9.6 0.3 2.5 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_33 PF13671.6 KLO20754.1 - 1.9 8.7 3.6 2 8.5 0.2 2.6 3 0 0 3 3 2 0 AAA domain Amidase PF01425.21 KLO20755.1 - 2.9e-89 300.1 0.0 3.6e-89 299.8 0.0 1.1 1 0 0 1 1 1 1 Amidase TB2_DP1_HVA22 PF03134.19 KLO20756.1 - 3.8e-23 81.2 6.2 6.2e-23 80.5 6.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GtrA PF04138.14 KLO20756.1 - 0.0029 17.8 3.5 0.004 17.4 3.5 1.4 1 1 0 1 1 1 1 GtrA-like protein DUF2052 PF09747.9 KLO20757.1 - 4.8e-06 26.9 21.6 7.5e-06 26.2 18.5 2.1 1 1 1 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Sec3_C PF09763.9 KLO20758.1 - 5.6e-171 570.4 2.1 8.6e-171 569.8 2.1 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KLO20758.1 - 9.8e-20 70.5 0.0 2.1e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 KLO20758.1 - 0.0014 17.5 2.3 0.0025 16.6 2.3 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family Rab5-bind PF09311.11 KLO20758.1 - 0.0096 15.4 5.1 0.024 14.0 5.1 1.6 1 0 0 1 1 1 1 Rabaptin-like protein SNAPc_SNAP43 PF09808.9 KLO20759.1 - 0.00067 19.6 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 His_Phos_2 PF00328.22 KLO20760.1 - 2.8e-25 89.5 0.0 5.3e-16 59.0 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) SE PF08491.10 KLO20761.1 - 5.1e-90 301.3 0.0 6.7e-90 300.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KLO20761.1 - 1.7e-09 37.7 0.0 0.0019 17.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KLO20761.1 - 6.1e-09 35.6 0.3 1.5e-07 31.0 0.3 2.5 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KLO20761.1 - 2.1e-05 23.8 3.5 0.016 14.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KLO20761.1 - 0.00012 21.5 0.1 0.00019 20.8 0.1 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KLO20761.1 - 0.00025 20.3 0.8 0.067 12.3 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Trp_halogenase PF04820.14 KLO20761.1 - 0.0019 17.2 0.6 0.34 9.7 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KLO20761.1 - 0.0038 17.4 0.0 0.0096 16.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KLO20761.1 - 0.0067 15.5 0.6 0.1 11.7 1.6 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein GMC_oxred_N PF00732.19 KLO20761.1 - 0.023 14.1 0.4 0.43 9.9 0.1 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox PF00070.27 KLO20761.1 - 0.082 13.5 0.2 0.55 10.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KLO20761.1 - 0.12 11.6 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KLO20761.1 - 0.12 12.4 0.2 0.6 10.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KLO20761.1 - 0.18 11.1 0.3 15 4.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ima1_N PF09779.9 KLO20762.1 - 1.3e-29 103.8 1.5 6.5e-29 101.5 1.5 2.0 1 1 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.7 KLO20762.1 - 0.33 11.0 4.9 1.6 8.8 1.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon Endomucin PF07010.12 KLO20763.1 - 0.0045 17.0 45.5 0.0055 16.7 45.5 1.1 1 0 0 1 1 1 1 Endomucin LAP1C PF05609.12 KLO20763.1 - 0.008 15.3 14.0 0.011 14.9 14.0 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) PgaD PF13994.6 KLO20763.1 - 0.099 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 PgaD-like protein Hid1 PF12722.7 KLO20763.1 - 0.18 9.9 11.7 0.23 9.6 11.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RIFIN PF02009.16 KLO20763.1 - 0.91 9.4 11.3 1.4 8.7 11.3 1.2 1 0 0 1 1 1 0 Rifin DUF4366 PF14283.6 KLO20763.1 - 3.9 7.5 11.9 1.3e+02 2.5 11.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) GREB1 PF15782.5 KLO20763.1 - 4.9 4.1 23.4 6.3 3.8 23.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NPR3 PF03666.13 KLO20763.1 - 5.1 5.8 13.7 8.6 5.0 13.7 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GCOM2 PF15328.6 KLO20763.1 - 5.1 7.4 18.8 6.8 7.0 18.8 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 CytochromB561_N PF09786.9 KLO20763.1 - 6.1 5.7 27.2 8.1 5.3 27.2 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Hepar_II_III PF07940.13 KLO20764.1 - 2.1e-07 30.8 0.5 3.6e-07 30.0 0.5 1.3 1 0 0 1 1 1 1 Heparinase II/III-like protein DUF4962 PF16332.5 KLO20764.1 - 7.9e-05 21.3 2.8 0.00013 20.6 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4962) TatD_DNase PF01026.21 KLO20765.1 - 1.5e-52 178.5 0.0 2e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Thiolase_N PF00108.23 KLO20766.1 - 1.1e-69 234.7 0.2 2.8e-69 233.4 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KLO20766.1 - 2e-46 156.6 0.6 3.8e-46 155.7 0.6 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 KLO20766.1 - 0.00013 22.0 0.0 0.00032 20.8 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KLO20766.1 - 0.0002 21.2 2.6 0.011 15.5 0.1 3.1 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KLO20766.1 - 0.001 18.7 2.0 0.0029 17.2 0.4 2.5 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Glyco_transf_21 PF13506.6 KLO20767.1 - 1.3e-26 93.1 0.3 1.3e-19 70.4 0.3 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KLO20767.1 - 2.7e-12 47.1 0.0 3.8e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KLO20767.1 - 0.0044 16.8 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 p450 PF00067.22 KLO20769.1 - 6.4e-65 219.7 0.2 1.4e-41 142.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 NCBP3 PF10309.9 KLO20770.1 - 1.7e-08 34.2 0.0 2.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KLO20770.1 - 3.5e-05 23.7 0.0 6.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RNA binding domain MMM1 PF10296.9 KLO20772.1 - 2.4e-09 36.7 0.0 5.7e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Adaptin_binding PF10199.9 KLO20773.1 - 0.051 14.2 0.1 0.37 11.4 0.0 2.6 2 2 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 WD40 PF00400.32 KLO20775.1 - 2.6e-38 129.3 20.8 5.4e-06 27.0 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KLO20775.1 - 9.5e-15 54.7 0.0 0.016 15.5 0.1 5.3 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KLO20775.1 - 0.00054 19.0 0.5 0.4 9.6 0.1 3.5 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KLO20775.1 - 0.0016 17.8 0.1 0.13 11.6 0.1 2.9 2 1 1 3 3 3 1 WD40-like domain eIF2A PF08662.11 KLO20775.1 - 0.0042 17.0 0.0 0.82 9.5 0.0 2.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A dsrm PF00035.26 KLO20777.1 - 3.9e-07 30.7 0.0 4.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.26 KLO20779.1 - 1.6e-11 44.7 0.0 1.8e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KLO20779.1 - 0.083 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Rsm22 PF09243.10 KLO20780.1 - 7.1e-43 146.9 0.0 2.7e-42 144.9 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 DUF2040 PF09745.9 KLO20780.1 - 0.69 10.0 6.5 0.74 9.9 0.7 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 55 (DUF2040) UCH PF00443.29 KLO20781.1 - 2.4e-24 86.3 0.0 3.4e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KLO20781.1 - 2.2e-10 40.7 0.1 4.2e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein MRP-L28 PF09812.9 KLO20782.1 - 4.2e-09 36.7 4.5 5.9e-07 29.8 1.3 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L28 PCI PF01399.27 KLO20783.1 - 8.8e-21 74.4 0.4 2.8e-20 72.8 0.4 1.9 1 0 0 1 1 1 1 PCI domain DUF5517 PF17639.2 KLO20783.1 - 0.046 14.0 1.5 0.14 12.5 0.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5517) MEIOC PF15189.6 KLO20783.1 - 0.27 10.8 2.5 0.69 9.5 0.1 2.3 2 0 0 2 2 2 0 Meiosis-specific coiled-coil domain-containing protein MEIOC PIP5K PF01504.18 KLO20784.1 - 1.3e-43 149.3 0.0 2.3e-35 122.1 0.1 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KLO20784.1 - 1.4e-29 103.1 0.0 2e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KLO20784.1 - 3.1e-18 65.7 8.3 3.1e-18 65.7 8.3 2.1 2 0 0 2 2 2 1 FYVE zinc finger NS3 PF17530.2 KLO20784.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Non-structural protein NS3 LTV PF04180.14 KLO20785.1 - 2.6e-90 303.9 29.8 8.7e-84 282.5 19.7 2.1 2 0 0 2 2 2 2 Low temperature viability protein F-box-like PF12937.7 KLO20790.1 - 0.0025 17.7 1.1 0.0075 16.1 0.2 2.2 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.13 KLO20790.1 - 0.2 12.4 0.6 2.2 9.1 0.1 2.7 2 0 0 2 2 2 0 Leucine Rich Repeat # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Schizopora_paradoxa-Schpa1/GCA_001020605.1_Schpa1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Schizopora_paradoxa-Schpa1/GCA_001020605.1_Schpa1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Schizopora_paradoxa-Schpa1/GCA_001020605.1_Schpa1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Schizopora_paradoxa-Schpa1/GCA_001020605.1_Schpa1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 06:23:30 2019 # [ok]